Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5205
• Symbol: ATP8B1
• Description: ATPase phospholipid transporting 8B1

DataSource: http://genomecrispr.dkfz.de/#!/results/ATP8B1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
57701246	57701269	18	+	26472758	Jiyoye	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.564321778226883	[251]	[280]	4	hSpCas9	negative selection	12795
57652566	57652589	18	-	26472758	Jiyoye	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	0.7383812899812467	[92]	[116]	5	hSpCas9	negative selection	12796
57661334	57661357	18	-	26472758	Jiyoye	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	0.4550039065964885	[88]	[91]	3	hSpCas9	negative selection	12797
57731697	57731720	18	-	26472758	Jiyoye	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.6457477298977556	[227]	[268]	5	hSpCas9	negative selection	12798
57697628	57697651	18	+	26472758	Jiyoye	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.5750170684476965	[153]	[172]	4	hSpCas9	negative selection	12799
57685089	57685112	18	+	26472758	Jiyoye	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.7850598823672513	[176]	[229]	5	hSpCas9	negative selection	12800
57684048	57684071	18	-	26472758	Jiyoye	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	-0.7744314249840742	[92]	[40]	-5	hSpCas9	negative selection	12801
57671470	57671493	18	-	26472758	Jiyoye	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	1.8578367905154383	[44]	[122]	8	hSpCas9	negative selection	12802
57662571	57662594	18	-	26472758	Jiyoye	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	0.8546343584770946	[65]	[89]	6	hSpCas9	negative selection	12803
57662505	57662528	18	+	26472758	Jiyoye	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	-1.096715508567965	[172]	[60]	-6	hSpCas9	negative selection	12804
57701246	57701269	18	+	26472758	KBM7	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.9966122672985702	[957,956]	[1126,701]	9	hSpCas9	negative selection	203913
57652566	57652589	18	-	26472758	KBM7	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	-0.32885669973011844	[515,517]	[146,236]	-3	hSpCas9	negative selection	203914
57661334	57661357	18	-	26472758	KBM7	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	-0.8290467539209065	[393,227]	[99,62]	-6	hSpCas9	negative selection	203915
57731697	57731720	18	-	26472758	KBM7	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.773731325296533	[881,793]	[525,804]	8	hSpCas9	negative selection	203916
57697628	57697651	18	+	26472758	KBM7	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.555667057548221	[533,442]	[410,268]	6	hSpCas9	negative selection	203917
57685089	57685112	18	+	26472758	KBM7	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.734238210324769	[1102,800]	[751,721]	7	hSpCas9	negative selection	203918
57684048	57684071	18	-	26472758	KBM7	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	-0.41899642690118766	[389,273]	[72,152]	-4	hSpCas9	negative selection	203919
57671470	57671493	18	-	26472758	KBM7	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	0.07763581313662073	[564,377]	[204,252]	0	hSpCas9	negative selection	203920
57662571	57662594	18	-	26472758	KBM7	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	0.8565953769026905	[212,170]	[191,135]	8	hSpCas9	negative selection	203921
57662505	57662528	18	+	26472758	KBM7	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	0.04509040181340329	[257,174]	[84,119]	0	hSpCas9	negative selection	203922
57701246	57701269	18	+	26472758	Raji	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.9801745153305035	[390]	[178]	8	hSpCas9	negative selection	395031
57652566	57652589	18	-	26472758	Raji	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	-0.6223504895615308	[198]	[29]	-5	hSpCas9	negative selection	395032
57661334	57661357	18	-	26472758	Raji	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	2.0766867381506833	[94]	[92]	9	hSpCas9	negative selection	395033
57731697	57731720	18	-	26472758	Raji	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.7315166333754335	[435]	[167]	6	hSpCas9	negative selection	395034
57697628	57697651	18	+	26472758	Raji	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.15521206046421443	[177]	[45]	1	hSpCas9	negative selection	395035
57685089	57685112	18	+	26472758	Raji	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.3046158828116473	[470]	[134]	3	hSpCas9	negative selection	395036
57684048	57684071	18	-	26472758	Raji	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	0.3673516381596097	[156]	[46]	3	hSpCas9	negative selection	395037
57671470	57671493	18	-	26472758	Raji	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	1.1073835353735997	[159]	[79]	8	hSpCas9	negative selection	395038
57662571	57662594	18	-	26472758	Raji	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	-0.22559974802275873	[130]	[25]	-2	hSpCas9	negative selection	395039
57662505	57662528	18	+	26472758	Raji	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	0.6923460360947556	[143]	[53]	6	hSpCas9	negative selection	395040
57701246	57701269	18	+	26472758	K562	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.5531329200010622	[1030]	[1276]	4	hSpCas9	negative selection	586149
57652566	57652589	18	-	26472758	K562	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	0.5772876853644644	[288]	[363]	5	hSpCas9	negative selection	586150
57661334	57661357	18	-	26472758	K562	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	0.981384321832653	[221]	[369]	8	hSpCas9	negative selection	586151
57731697	57731720	18	-	26472758	K562	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.7145922493210077	[814]	[1128]	6	hSpCas9	negative selection	586152
57697628	57697651	18	+	26472758	K562	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.5261896960818265	[356]	[433]	4	hSpCas9	negative selection	586153
57685089	57685112	18	+	26472758	K562	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.674563119335499	[664]	[895]	5	hSpCas9	negative selection	586154
57684048	57684071	18	-	26472758	K562	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	1.1576139001291743	[273]	[515]	8	hSpCas9	negative selection	586155
57671470	57671493	18	-	26472758	K562	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	0.6802897303624562	[274]	[371]	5	hSpCas9	negative selection	586156
57662571	57662594	18	-	26472758	K562	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	-0.7073261037263321	[146]	[75]	-4	hSpCas9	negative selection	586157
57662505	57662528	18	+	26472758	K562	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	0.41434372910875933	[207]	[233]	3	hSpCas9	negative selection	586158
57688503	57688526	18	-	26627737	DLD1	viability	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.6108621097890239	[590]	[268,353,233]	6	hSpCas9	negative selection	801777
57691864	57691887	18	+	26627737	DLD1	viability	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.24993101642692522	[297]	[99,157,80]	2	hSpCas9	negative selection	801778
57695188	57695211	18	-	26627737	DLD1	viability	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-0.31673255948957185	[349]	[97,105,63]	-3	hSpCas9	negative selection	801779
57701244	57701267	18	+	26627737	DLD1	viability	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.6037154765053399	[603]	[339,287,239]	6	hSpCas9	negative selection	801780
57704554	57704577	18	+	26627737	DLD1	viability	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	0.7490678701851423	[156]	[43,68,126]	7	hSpCas9	negative selection	801781
57731626	57731649	18	-	26627737	DLD1	viability	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.6278305329011907	[827]	[382,477,349]	6	hSpCas9	negative selection	801782
57688503	57688526	18	-	26627737	GBM cells	viability after 5 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.4838763756068417	[429]	[304,339]	7	hSpCas9	negative selection	884092
57691864	57691887	18	+	26627737	GBM cells	viability after 5 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.06318915426234167	[198]	[102,119]	1	hSpCas9	negative selection	884093
57695188	57695211	18	-	26627737	GBM cells	viability after 5 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-0.06424935693394307	[115]	[60,57]	-1	hSpCas9	negative selection	884094
57701244	57701267	18	+	26627737	GBM cells	viability after 5 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	-0.0034228658961708014	[513]	[258,290]	0	hSpCas9	negative selection	884095
57704554	57704577	18	+	26627737	GBM cells	viability after 5 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	-0.24918476410344848	[245]	[123,97]	-4	hSpCas9	negative selection	884096
57731626	57731649	18	-	26627737	GBM cells	viability after 5 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.25597397287811585	[786]	[493,513]	4	hSpCas9	negative selection	884097
57688503	57688526	18	-	26627737	GBM cells	viability after 13 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.4682821590415812	[429]	[351,298]	6	hSpCas9	negative selection	966407
57691864	57691887	18	+	26627737	GBM cells	viability after 13 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.03453260834945915	[198]	[114,106]	0	hSpCas9	negative selection	966408
57695188	57695211	18	-	26627737	GBM cells	viability after 13 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	0.14519849393889972	[115]	[30,100]	1	hSpCas9	negative selection	966409
57701244	57701267	18	+	26627737	GBM cells	viability after 13 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.03924011922318127	[513]	[333,247]	0	hSpCas9	negative selection	966410
57704554	57704577	18	+	26627737	GBM cells	viability after 13 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	-0.1149675453828809	[245]	[141,107]	-1	hSpCas9	negative selection	966411
57731626	57731649	18	-	26627737	GBM cells	viability after 13 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.345303962172685	[786]	[606,489]	4	hSpCas9	negative selection	966412
57688503	57688526	18	-	26627737	GBM cells	viability after 21 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	1.1612049544933898	[429]	[546,499]	9	hSpCas9	negative selection	1048722
57691864	57691887	18	+	26627737	GBM cells	viability after 21 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.13613463087196362	[198]	[134,103]	1	hSpCas9	negative selection	1048723
57695188	57695211	18	-	26627737	GBM cells	viability after 21 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	0.8076866082887686	[115]	[102,116]	7	hSpCas9	negative selection	1048724
57701244	57701267	18	+	26627737	GBM cells	viability after 21 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.1797584960518115	[513]	[320,311]	2	hSpCas9	negative selection	1048725
57704554	57704577	18	+	26627737	GBM cells	viability after 21 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	0.7934870665148783	[245]	[239,223]	7	hSpCas9	negative selection	1048726
57731626	57731649	18	-	26627737	GBM cells	viability after 21 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.3419258917054222	[786]	[543,539]	3	hSpCas9	negative selection	1048727
57688503	57688526	18	-	26627737	RPE1	viability after 9 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	1.0106266761748413	[1224]	[618,970]	6	hSpCas9	negative selection	1131037
57691864	57691887	18	+	26627737	RPE1	viability after 9 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.025854029064675932	[696]	[267,162]	0	hSpCas9	negative selection	1131038
57695188	57695211	18	-	26627737	RPE1	viability after 9 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-0.4216931629837253	[275]	[67,59]	-3	hSpCas9	negative selection	1131039
57701244	57701267	18	+	26627737	RPE1	viability after 9 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	-0.02675419750279584	[2337]	[473,1033]	0	hSpCas9	negative selection	1131040
57704554	57704577	18	+	26627737	RPE1	viability after 9 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	-0.026345357541654124	[653]	[221,173]	0	hSpCas9	negative selection	1131041
57731626	57731649	18	-	26627737	RPE1	viability after 9 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.5888944942450394	[2561]	[1253,1144]	4	hSpCas9	negative selection	1131042
57688503	57688526	18	-	26627737	RPE1	viability after 12 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.602669993919446	[1224]	[457,543]	4	hSpCas9	negative selection	1213352
57691864	57691887	18	+	26627737	RPE1	viability after 12 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.6137036891983078	[696]	[338,230]	4	hSpCas9	negative selection	1213353
57695188	57695211	18	-	26627737	RPE1	viability after 12 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-0.3780774446060253	[275]	[41,72]	-3	hSpCas9	negative selection	1213354
57701244	57701267	18	+	26627737	RPE1	viability after 12 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	-0.09142500190908809	[2337]	[387,802]	0	hSpCas9	negative selection	1213355
57704554	57704577	18	+	26627737	RPE1	viability after 12 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	-0.2129094705412155	[653]	[154,147]	-1	hSpCas9	negative selection	1213356
57731626	57731649	18	-	26627737	RPE1	viability after 12 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.5839243864536225	[2561]	[920,1148]	4	hSpCas9	negative selection	1213357
57688503	57688526	18	-	26627737	RPE1	viability after 15 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.6458015341122305	[1224]	[475,605]	4	hSpCas9	negative selection	1295667
57691864	57691887	18	+	26627737	RPE1	viability after 15 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.31603401230583056	[696]	[444,52]	2	hSpCas9	negative selection	1295668
57695188	57695211	18	-	26627737	RPE1	viability after 15 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-2.1886005574246123	[275]	[9,23]	-8	hSpCas9	negative selection	1295669
57701244	57701267	18	+	26627737	RPE1	viability after 15 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	-0.10076569422024972	[2337]	[236,982]	0	hSpCas9	negative selection	1295670
57704554	57704577	18	+	26627737	RPE1	viability after 15 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	0.2048126413345111	[653]	[256,170]	1	hSpCas9	negative selection	1295671
57731626	57731649	18	-	26627737	RPE1	viability after 15 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.5177124249733653	[2561]	[1341,743]	3	hSpCas9	negative selection	1295672
57688503	57688526	18	-	26627737	RPE1	viability after 18 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.601746556674899	[1224]	[477,526]	4	hSpCas9	negative selection	1377982
57691864	57691887	18	+	26627737	RPE1	viability after 18 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.5993995486758679	[696]	[371,191]	4	hSpCas9	negative selection	1377983
57695188	57695211	18	-	26627737	RPE1	viability after 18 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-0.5681787410466879	[275]	[27,73]	-4	hSpCas9	negative selection	1377984
57701244	57701267	18	+	26627737	RPE1	viability after 18 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.41479866077128325	[2337]	[640,1054]	2	hSpCas9	negative selection	1377985
57704554	57704577	18	+	26627737	RPE1	viability after 18 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	-0.541623530624193	[653]	[113,128]	-3	hSpCas9	negative selection	1377986
57731626	57731649	18	-	26627737	RPE1	viability after 18 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.6384888442057579	[2561]	[1230,910]	4	hSpCas9	negative selection	1377987
57688503	57688526	18	-	26627737	HeLa	viability after 8 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.5359116261251619	[464]	[343,294,254]	5	hSpCas9	negative selection	1460297
57691864	57691887	18	+	26627737	HeLa	viability after 8 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.04826533166267949	[337]	[206,222,45]	0	hSpCas9	negative selection	1460298
57695188	57695211	18	-	26627737	HeLa	viability after 8 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	0.10579541118562497	[199]	[70,22,175]	1	hSpCas9	negative selection	1460299
57701244	57701267	18	+	26627737	HeLa	viability after 8 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.39640450293964147	[866]	[530,376,582]	3	hSpCas9	negative selection	1460300
57704554	57704577	18	+	26627737	HeLa	viability after 8 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	-0.6567662858527168	[414]	[175,93,88]	-6	hSpCas9	negative selection	1460301
57731626	57731649	18	-	26627737	HeLa	viability after 8 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.4526314272725427	[1019]	[683,679,483]	4	hSpCas9	negative selection	1460302
57688503	57688526	18	-	26627737	HeLa	viability after 12 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	1.138341324475309	[464]	[428,443,393]	7	hSpCas9	negative selection	1542612
57691864	57691887	18	+	26627737	HeLa	viability after 12 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	-0.5713337436847934	[337]	[111,117,49]	-5	hSpCas9	negative selection	1542613
57695188	57695211	18	-	26627737	HeLa	viability after 12 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-0.013060751984967589	[199]	[3,123,110]	0	hSpCas9	negative selection	1542614
57701244	57701267	18	+	26627737	HeLa	viability after 12 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	-0.1830999885364537	[866]	[390,220,346]	-2	hSpCas9	negative selection	1542615
57704554	57704577	18	+	26627737	HeLa	viability after 12 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	-0.5959047611144684	[414]	[87,100,151]	-5	hSpCas9	negative selection	1542616
57731626	57731649	18	-	26627737	HeLa	viability after 12 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	-0.057770169265765725	[1019]	[432,449,327]	0	hSpCas9	negative selection	1542617
57688503	57688526	18	-	26627737	HeLa	viability after 15 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.3099087029446458	[464]	[224,257,219]	2	hSpCas9	negative selection	1624927
57691864	57691887	18	+	26627737	HeLa	viability after 15 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	-0.8231418565182831	[337]	[128,57,42]	-6	hSpCas9	negative selection	1624928
57695188	57695211	18	-	26627737	HeLa	viability after 15 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	0.41434028135176004	[199]	[75,176,69]	3	hSpCas9	negative selection	1624929
57701244	57701267	18	+	26627737	HeLa	viability after 15 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.24265274540223292	[866]	[534,386,321]	2	hSpCas9	negative selection	1624930
57704554	57704577	18	+	26627737	HeLa	viability after 15 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	0.06280232526059172	[414]	[170,247,104]	0	hSpCas9	negative selection	1624931
57731626	57731649	18	-	26627737	HeLa	viability after 15 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.35573566927991496	[1019]	[533,468,595]	3	hSpCas9	negative selection	1624932
57688503	57688526	18	-	26627737	HeLa	viability after 18 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.3551099079167974	[464]	[161,217,219]	3	hSpCas9	negative selection	1707242
57691864	57691887	18	+	26627737	HeLa	viability after 18 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	-0.8892454246843517	[337]	[78,48,42]	-7	hSpCas9	negative selection	1707243
57695188	57695211	18	-	26627737	HeLa	viability after 18 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	0.454501066883345	[199]	[50,153,69]	4	hSpCas9	negative selection	1707244
57701244	57701267	18	+	26627737	HeLa	viability after 18 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.30023164262793833	[866]	[397,312,321]	2	hSpCas9	negative selection	1707245
57704554	57704577	18	+	26627737	HeLa	viability after 18 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	0.0483739577523231	[414]	[105,211,104]	0	hSpCas9	negative selection	1707246
57731626	57731649	18	-	26627737	HeLa	viability after 18 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.3693890536833444	[1019]	[361,395,595]	3	hSpCas9	negative selection	1707247
57688503	57688526	18	-	26627737	HCT116	viability after 6 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.3553595134652128	[704]	[86,171]	2	hSpCas9	negative selection	1789557
57691864	57691887	18	+	26627737	HCT116	viability after 6 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	-0.057935825958945975	[288]	[42,43]	0	hSpCas9	negative selection	1789558
57695188	57695211	18	-	26627737	HCT116	viability after 6 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	1.7006462543645695	[255]	[37,181]	8	hSpCas9	negative selection	1789559
57701244	57701267	18	+	26627737	HCT116	viability after 6 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.952810011377385	[1461]	[625,344]	5	hSpCas9	negative selection	1789560
57704554	57704577	18	+	26627737	HCT116	viability after 6 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	0.8690534496275301	[228]	[77,58]	5	hSpCas9	negative selection	1789561
57731626	57731649	18	-	26627737	HCT116	viability after 6 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	-0.16184733327826262	[2246]	[298,324]	-1	hSpCas9	negative selection	1789562
57688503	57688526	18	-	26627737	HCT116	viability after 8 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	-0.02798039387201423	[463]	[221,296,232]	0	hSpCas9	negative selection	1871872
57691864	57691887	18	+	26627737	HCT116	viability after 8 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.5629452721983114	[174]	[202,128,96]	5	hSpCas9	negative selection	1871873
57695188	57695211	18	-	26627737	HCT116	viability after 8 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-0.46069288984483114	[213]	[165,48,43]	-5	hSpCas9	negative selection	1871874
57701244	57701267	18	+	26627737	HCT116	viability after 8 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.7060341410018632	[471]	[314,375,577]	6	hSpCas9	negative selection	1871875
57704554	57704577	18	+	26627737	HCT116	viability after 8 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	0.7582381646756393	[155]	[119,109,204]	7	hSpCas9	negative selection	1871876
57731626	57731649	18	-	26627737	HCT116	viability after 8 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.8105294618931423	[441]	[448,416,415]	7	hSpCas9	negative selection	1871877
57688503	57688526	18	-	26627737	HCT116	viability after 9 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	-0.6727455447400332	[704]	[183,65]	-5	hSpCas9	negative selection	1954187
57691864	57691887	18	+	26627737	HCT116	viability after 9 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.4662984422526977	[288]	[157,65]	3	hSpCas9	negative selection	1954188
57695188	57695211	18	-	26627737	HCT116	viability after 9 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-0.28533619352745765	[255]	[121,3]	-2	hSpCas9	negative selection	1954189
57701244	57701267	18	+	26627737	HCT116	viability after 9 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.032549161403659266	[1461]	[572,261]	0	hSpCas9	negative selection	1954190
57704554	57704577	18	+	26627737	HCT116	viability after 9 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	-0.3871110198483383	[228]	[91,10]	-3	hSpCas9	negative selection	1954191
57731626	57731649	18	-	26627737	HCT116	viability after 9 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	-1.1015089695727294	[2246]	[268,287]	-7	hSpCas9	negative selection	1954192
57688503	57688526	18	-	26627737	HCT116	viability after 12 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.23964413474783153	[463]	[200,231,436]	2	hSpCas9	negative selection	2036502
57691864	57691887	18	+	26627737	HCT116	viability after 12 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.4031535550806489	[174]	[146,95,118]	4	hSpCas9	negative selection	2036503
57695188	57695211	18	-	26627737	HCT116	viability after 12 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-0.3042265978416455	[213]	[112,77,79]	-3	hSpCas9	negative selection	2036504
57701244	57701267	18	+	26627737	HCT116	viability after 12 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.2996474562797894	[471]	[215,355,352]	3	hSpCas9	negative selection	2036505
57704554	57704577	18	+	26627737	HCT116	viability after 12 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	-0.4722547614752518	[155]	[73,59,41]	-5	hSpCas9	negative selection	2036506
57731626	57731649	18	-	26627737	HCT116	viability after 12 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.4583774248010831	[441]	[242,353,367]	4	hSpCas9	negative selection	2036507
57688503	57688526	18	-	26627737	HCT116	viability after 15 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	-0.07235525862989567	[463]	[243,247,266]	0	hSpCas9	negative selection	2118817
57691864	57691887	18	+	26627737	HCT116	viability after 15 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.5905341905758487	[174]	[224,88,148]	5	hSpCas9	negative selection	2118818
57695188	57695211	18	-	26627737	HCT116	viability after 15 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-0.4969566463949522	[213]	[60,102,93]	-5	hSpCas9	negative selection	2118819
57701244	57701267	18	+	26627737	HCT116	viability after 15 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.7105406397036141	[471]	[310,426,574]	6	hSpCas9	negative selection	2118820
57704554	57704577	18	+	26627737	HCT116	viability after 15 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	0.48443256457456757	[155]	[194,105,83]	4	hSpCas9	negative selection	2118821
57731626	57731649	18	-	26627737	HCT116	viability after 15 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.7510061472700248	[441]	[364,395,511]	6	hSpCas9	negative selection	2118822
57688503	57688526	18	-	26627737	HCT116	viability after 18 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	-0.3440076397288517	[463]	[167,181,179]	-3	hSpCas9	negative selection	2201132
57691864	57691887	18	+	26627737	HCT116	viability after 18 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	1.188272384754543	[174]	[251,128,201]	8	hSpCas9	negative selection	2201133
57695188	57695211	18	-	26627737	HCT116	viability after 18 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	0.03316870656453047	[213]	[76,79,164]	0	hSpCas9	negative selection	2201134
57701244	57701267	18	+	26627737	HCT116	viability after 18 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.6985834445295501	[471]	[242,413,454]	6	hSpCas9	negative selection	2201135
57704554	57704577	18	+	26627737	HCT116	viability after 18 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	-0.6363560641937404	[155]	[58,48,36]	-5	hSpCas9	negative selection	2201136
57731626	57731649	18	-	26627737	HCT116	viability after 18 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.8092160104304055	[441]	[322,380,420]	6	hSpCas9	negative selection	2201137
57678541	57678564	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACACCATTGCACTCCAGCCCAG	ATP8B1	ENSG00000081923	1.262249387691805	[54,80]	[6,66]	5	dCas9-VP64	positive selection	2396351
57678862	57678885	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACACCATTGCACTCCAGCCCAG	ATP8B1	ENSG00000081923	1.262249387691805	[54,80]	[6,66]	5	dCas9-VP64	positive selection	2396352
57676474	57676497	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATTTGGGAGGCTGAGGCAGGTAG	ATP8B1	ENSG00000081923	1.0311422578945828	[46,428]	[158,53]	4	dCas9-VP64	positive selection	2400091
57713613	57713636	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACCTCTAATCCCAGCTACTCGGG	ATP8B1	ENSG00000081923	-0.6235089132009077	[202,440]	[53,36]	-3	dCas9-VP64	positive selection	2400811
57733660	57733683	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCACTGCACTCCAGCCCGG	ATP8B1	ENSG00000081923	0.6031003623548207	[86,54]	[14,31]	2	dCas9-VP64	positive selection	2416257
57688715	57688738	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGGCTCCACCCTTATGAATGG	ATP8B1	ENSG00000081923	1.42721215921247	[109,209]	[9,186]	5	dCas9-VP64	positive selection	2417872
57708123	57708146	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCCAGCCTGGGCGACAGACGG	ATP8B1	ENSG00000081923	1.2012671036636573	[14,1]	[1,5]	5	dCas9-VP64	positive selection	2454988
57751050	57751073	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGCAGAGGTTGCAGTGAGGAG	ATP8B1	ENSG00000081923	2.8458860914044886	[4,6]	[4,13]	8	dCas9-VP64	positive selection	2464578
57736056	57736079	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTGAGAACATGTGGTGTTTAG	ATP8B1	ENSG00000081923	-1.1334071955764224	[258,107]	[23,10]	-6	dCas9-VP64	positive selection	2468874
57676917	57676940	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGGATCACTTGAGCCCAGG	ATP8B1	ENSG00000081923	1.3448043646809227	[134,24]	[56,28]	5	dCas9-VP64	positive selection	2469814
57697106	57697129	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGTGTGGGGG	ATP8B1	ENSG00000081923	-2.5797701712444865	[504,29]	[12,4]	-9	dCas9-VP64	positive selection	2473400
57678541	57678564	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACACCATTGCACTCCAGCCCAG	ATP8B1	ENSG00000081923	1.3472067688576927	[201,316]	[301,132]	7	dCas9-VP64	positive selection	2491606
57678862	57678885	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACACCATTGCACTCCAGCCCAG	ATP8B1	ENSG00000081923	1.3472067688576927	[201,316]	[301,132]	7	dCas9-VP64	positive selection	2491607
57676474	57676497	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATTTGGGAGGCTGAGGCAGGTAG	ATP8B1	ENSG00000081923	0.6350691816100226	[174,241]	[44,161]	5	dCas9-VP64	positive selection	2495346
57713613	57713636	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACCTCTAATCCCAGCTACTCGGG	ATP8B1	ENSG00000081923	-0.3343030432183025	[506,132]	[127,41]	-3	dCas9-VP64	positive selection	2496066
57733660	57733683	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCACTGCACTCCAGCCCGG	ATP8B1	ENSG00000081923	-0.5652196159145948	[243,309]	[59,60]	-5	dCas9-VP64	positive selection	2511512
57688715	57688738	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGGCTCCACCCTTATGAATGG	ATP8B1	ENSG00000081923	1.2759664038869951	[74,72]	[36,78]	7	dCas9-VP64	positive selection	2513127
57708123	57708146	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCCAGCCTGGGCGACAGACGG	ATP8B1	ENSG00000081923	0.32779538109836626	[14,14]	[4,6]	2	dCas9-VP64	positive selection	2550243
57751050	57751073	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGCAGAGGTTGCAGTGAGGAG	ATP8B1	ENSG00000081923	0.5694698539005818	[43,11]	[11,14]	4	dCas9-VP64	positive selection	2559833
57736056	57736079	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTGAGAACATGTGGTGTTTAG	ATP8B1	ENSG00000081923	-0.007859909983208867	[140,86]	[47,26]	0	dCas9-VP64	positive selection	2564129
57676917	57676940	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGGATCACTTGAGCCCAGG	ATP8B1	ENSG00000081923	0.9689409693551694	[107,845]	[92,495]	6	dCas9-VP64	positive selection	2565069
57697106	57697129	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGTGTGGGGG	ATP8B1	ENSG00000081923	0.3593778947128078	[15,191]	[23,59]	3	dCas9-VP64	positive selection	2568655
57701273	57701296	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TAGTGTGGTGTACCAAGCCAGGG	ATP8B1	ENSG00000081923	-0.0041642754929465675	[3,3]	[4,2]	0	hSpCas9	positive selection	2972554
57691900	57691923	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCATCATAGAGGTACCAAGAGG	ATP8B1	ENSG00000081923	-0.5383518680062424	[3,3]	[3,0]	-7	hSpCas9	positive selection	2972555
57701273	57701296	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TAGTGTGGTGTACCAAGCCAGGG	ATP8B1	ENSG00000081923	-0.15279593698752816	[3,3]	[3,1]	-2	hSpCas9	positive selection	3040412
57691900	57691923	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCATCATAGAGGTACCAAGAGG	ATP8B1	ENSG00000081923	-0.15485699101339723	[3,3]	[2,1]	-2	hSpCas9	positive selection	3040413
57706518	57706541		+	24336571	A375	resistance to PLX after 7 days	AATTTTGTGTTCATAAAGTGAGG	ATP8B1	ENSG00000081923	-0.09161054950531722	[7,7]	[6,7]	-3	hSpCas9	positive selection	3138932
57706504	57706527		-	24336571	A375	resistance to PLX after 7 days	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.34083979427562383	[3,3]	[2,2]	-8	hSpCas9	positive selection	3138942
57701085	57701108		-	24336571	A375	resistance to PLX after 7 days	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.2204390556584428	[3,3]	[4,5]	6	hSpCas9	positive selection	3138953
57706518	57706541		+	24336571	A375	resistance to PLX after 14 days	AATTTTGTGTTCATAAAGTGAGG	ATP8B1	ENSG00000081923	0.10568239473793839	[6,8]	[2,3]	1	hSpCas9	positive selection	3196725
57706504	57706527		-	24336571	A375	resistance to PLX after 14 days	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.10382536375582463	[3,3]	[1,1]	-1	hSpCas9	positive selection	3196735
57701085	57701108		-	24336571	A375	resistance to PLX after 14 days	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.8755092542422871	[4,7]	[4,5]	7	hSpCas9	positive selection	3196746
57706518	57706541		+	24336571	A375	viability after 7 days	AATTTTGTGTTCATAAAGTGAGG	ATP8B1	ENSG00000081923	-0.14460393181184772	[8]	[7,7]	-2	hSpCas9	negative selection	3254518
57706504	57706527		-	24336571	A375	viability after 7 days	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.2555232220120798	[4]	[3,3]	-4	hSpCas9	negative selection	3254528
57701085	57701108		-	24336571	A375	viability after 7 days	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	-0.0895693863826228	[4]	[3,3]	-1	hSpCas9	negative selection	3254539
57706518	57706541		+	24336571	A375	viability after 14 days	AATTTTGTGTTCATAAAGTGAGG	ATP8B1	ENSG00000081923	-0.13130583529180428	[8]	[6,8]	-1	hSpCas9	negative selection	3312311
57706504	57706527		-	24336571	A375	viability after 14 days	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.1250348127211458	[4]	[3,3]	-1	hSpCas9	negative selection	3312321
57701085	57701108		-	24336571	A375	viability after 14 days	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.44125096168316946	[4]	[4,7]	5	hSpCas9	negative selection	3312332
57701085	57701108	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	1.340412509670856	[47,72]	[0,0]	6	hSpCas9	positive selection	3338213
57701046	57701069	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.855387056724381	[93,74]	[0,0]	4	hSpCas9	positive selection	3338214
57697849	57697872	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.48914188666890873	[108,108]	[0,0]	2	hSpCas9	positive selection	3357470
57706504	57706527	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.6130385081375694	[233,233]	[0,0]	-4	hSpCas9	positive selection	3357471
57695188	57695211	18	-	26780180	HT29	viability (Avana library 4 designs)	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	0.498511996465802	[]	[]	1	hSpCas9	negative selection	3408705
57695171	57695194	18	+	26780180	HT29	viability (Avana library 4 designs)	CTGCAAAAATGACTAAGCCGTGG	ATP8B1	ENSG00000081923	0.816335338771459	[]	[]	3	hSpCas9	negative selection	3408706
57701272	57701295	18	+	26780180	HT29	viability (Avana library 4 designs)	TAGTGTGGTGTACCAAGCCAGGG	ATP8B1	ENSG00000081923	0.881101824327071	[]	[]	3	hSpCas9	negative selection	3408707
57691899	57691922	18	+	26780180	HT29	viability (Avana library 4 designs)	TCCATCATAGAGGTACCAAGAGG	ATP8B1	ENSG00000081923	0.245285278737443	[]	[]	0	hSpCas9	negative selection	3408708
57695171	57695194	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGCAAAAATGACTAAGCCGTGG	ATP8B1	ENSG00000081923	3.86728808650694	[]	[]	6	hSpCas9	negative selection	3482375
57695188	57695211	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	1.2857659538091	[]	[]	1	hSpCas9	negative selection	3482376
57701272	57701295	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	TAGTGTGGTGTACCAAGCCAGGG	ATP8B1	ENSG00000081923	1.68907449282039	[]	[]	2	hSpCas9	negative selection	3482377
57691899	57691922	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCATCATAGAGGTACCAAGAGG	ATP8B1	ENSG00000081923	-1.96672698358932	[]	[]	-2	hSpCas9	negative selection	3482378
57695171	57695194	18	+	26780180	A375	viability (Avana lentiGuide)	CTGCAAAAATGACTAAGCCGTGG	ATP8B1	ENSG00000081923	-2.68862515852783	[]	[]	-5	hSpCas9	negative selection	3591034
57695188	57695211	18	-	26780180	A375	viability (Avana lentiGuide)	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-2.31836744417402	[]	[]	-4	hSpCas9	negative selection	3591035
57701272	57701295	18	+	26780180	A375	viability (Avana lentiGuide)	TAGTGTGGTGTACCAAGCCAGGG	ATP8B1	ENSG00000081923	-0.430928836648371	[]	[]	0	hSpCas9	negative selection	3591036
57691899	57691922	18	+	26780180	A375	viability (Avana lentiGuide)	TCCATCATAGAGGTACCAAGAGG	ATP8B1	ENSG00000081923	-7.83060046284658	[]	[]	-9	hSpCas9	negative selection	3591037
57695171	57695194	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGCAAAAATGACTAAGCCGTGG	ATP8B1	ENSG00000081923	0.16751945072782704	[4]	[5,5]	4	hSpCas9	positive selection	3699693
57695188	57695211	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-0.187402055595967	[5]	[5,3]	-3	hSpCas9	positive selection	3699694
57701272	57701295	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAGTGTGGTGTACCAAGCCAGGG	ATP8B1	ENSG00000081923	0.14646843666508017	[4]	[5,5]	4	hSpCas9	positive selection	3699695
57691899	57691922	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCATCATAGAGGTACCAAGAGG	ATP8B1	ENSG00000081923	-0.3224558386016449	[4]	[3,3]	-5	hSpCas9	positive selection	3699696
57695171	57695194	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGCAAAAATGACTAAGCCGTGG	ATP8B1	ENSG00000081923	-0.28039392547329545	[5]	[3,3]	-4	hSpCas9	positive selection	3808300
57695188	57695211	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	-0.39191115541935717	[5]	[4,2]	-5	hSpCas9	positive selection	3808301
57701272	57701295	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAGTGTGGTGTACCAAGCCAGGG	ATP8B1	ENSG00000081923	0.24031846066734477	[5]	[6,4]	6	hSpCas9	positive selection	3808302
57691899	57691922	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCATCATAGAGGTACCAAGAGG	ATP8B1	ENSG00000081923	0.284385647473733	[5]	[4,5]	7	hSpCas9	positive selection	3808303
57706504	57706527	18	-	26780180	A375	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.372392895003718	[]	[]	0	hSpCas9	negative selection	3916549
57701046	57701069	18	-	26780180	A375	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	1.0923107432996	[]	[]	5	hSpCas9	negative selection	3916550
57701085	57701108	18	-	26780180	A375	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.898452420653131	[]	[]	4	hSpCas9	negative selection	3916551
57697849	57697872	18	-	26780180	A375	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	1.11746624821979	[]	[]	5	hSpCas9	negative selection	3916552
57706504	57706527	18	-	26780180	HT29	viability (GeCKOv2 library)	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.0379444945207877	[]	[]	0	hSpCas9	negative selection	4024515
57701046	57701069	18	-	26780180	HT29	viability (GeCKOv2 library)	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.48338718972039	[]	[]	1	hSpCas9	negative selection	4024516
57701085	57701108	18	-	26780180	HT29	viability (GeCKOv2 library)	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	1.13935910117328	[]	[]	5	hSpCas9	negative selection	4024517
57697849	57697872	18	-	26780180	HT29	viability (GeCKOv2 library)	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	1.14185040426576	[]	[]	5	hSpCas9	negative selection	4024518
57706518	57706541	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATTTTGTGTTCATAAAGTGAGG	ATP8B1	ENSG00000081923	-0.10040219872315687	[3]	[1,1]	-2	hSpCas9	positive selection	4164229
57706504	57706527	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.21518970223134581	[1]	[0,0]	-5	hSpCas9	positive selection	4164240
57701085	57701108	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.5576940318883558	[1]	[0,2]	9	hSpCas9	positive selection	4164251
57706518	57706541	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATTTTGTGTTCATAAAGTGAGG	ATP8B1	ENSG00000081923	-0.05735048969410925	[3]	[1,0,1,0]	-1	hSpCas9	positive selection	4228251
57706504	57706527	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.8539831914289813	[3]	[0,2,1,3]	5	hSpCas9	positive selection	4228262
57701085	57701108	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	-0.33484411586121654	[3]	[0,0,2,0]	-5	hSpCas9	positive selection	4228273
57701085	57701108	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	-0.34239634873112323	[1]	[1,0]	-6	hSpCas9	positive selection	4257482
57701046	57701069	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.3193431499148772	[2]	[1,2]	6	hSpCas9	positive selection	4257483
57668141	57668164	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	-0.22493469180437237	[3]	[3,0]	-4	hSpCas9	positive selection	4280515
57697849	57697872	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.3254333862312199	[2]	[3,1]	6	hSpCas9	positive selection	4321766
57706504	57706527	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.11794706420988116	[3]	[3,1]	-2	hSpCas9	positive selection	4321767
57668666	57668689	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.058146072026049656	[1]	[1,0]	1	hSpCas9	positive selection	4344773
57688491	57688513	18	+	27760321	OCIAML3	viability	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	0.7424057405909369	[714,640]	[770,1035]	8	hSpCas9	negative selection	4380745
57691873	57691895	18	-	27760321	OCIAML3	viability	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	0.44243744414250136	[656,531]	[660,585]	5	hSpCas9	negative selection	4380746
57691939	57691961	18	+	27760321	OCIAML3	viability	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	0.6741464547481183	[652,512]	[684,771]	7	hSpCas9	negative selection	4380747
57701079	57701101	18	-	27760321	OCIAML3	viability	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4380748
57701272	57701294	18	+	27760321	OCIAML3	viability	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	0.6657251852854917	[435,386]	[441,597]	7	hSpCas9	negative selection	4380749
57688491	57688513	18	+	27760321	OCIAML2	viability	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	0.15839820126672977	[714,640]	[553,686]	2	hSpCas9	negative selection	4464208
57691873	57691895	18	-	27760321	OCIAML2	viability	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	-0.29490666003226096	[656,531]	[338,456]	-4	hSpCas9	negative selection	4464209
57691939	57691961	18	+	27760321	OCIAML2	viability	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	0.54826384850361	[652,512]	[581,820]	7	hSpCas9	negative selection	4464210
57701079	57701101	18	-	27760321	OCIAML2	viability	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4464211
57701272	57701294	18	+	27760321	OCIAML2	viability	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	0.12387855470419892	[435,386]	[318,418]	1	hSpCas9	negative selection	4464212
57688491	57688513	18	+	27760321	MV411	viability	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	0.6618599620811306	[714,640]	[483,1041]	5	hSpCas9	negative selection	4547671
57691873	57691895	18	-	27760321	MV411	viability	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	-0.05298539520543222	[656,531]	[65,841]	0	hSpCas9	negative selection	4547672
57691939	57691961	18	+	27760321	MV411	viability	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	1.2264411999623346	[652,512]	[763,1089]	8	hSpCas9	negative selection	4547673
57701079	57701101	18	-	27760321	MV411	viability	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	0.5949485011219959	[0,0]	[0,0]	4	hSpCas9	negative selection	4547674
57701272	57701294	18	+	27760321	MV411	viability	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	0.9166653164682492	[435,386]	[745,159]	6	hSpCas9	negative selection	4547675
57688491	57688513	18	+	27760321	HL60	viability	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	-0.1436513139297394	[714,640]	[591,403]	-2	hSpCas9	negative selection	4631134
57691873	57691895	18	-	27760321	HL60	viability	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	0.27123628755471135	[656,531]	[398,777]	3	hSpCas9	negative selection	4631135
57691939	57691961	18	+	27760321	HL60	viability	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	0.449564994811412	[652,512]	[615,677]	5	hSpCas9	negative selection	4631136
57701079	57701101	18	-	27760321	HL60	viability	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4631137
57701272	57701294	18	+	27760321	HL60	viability	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	-0.013877772688115186	[435,386]	[361,300]	0	hSpCas9	negative selection	4631138
57688491	57688513	18	+	27760321	HT1080	viability	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	0.1240731834304094	[640,499]	[166,335]	0	hSpCas9	negative selection	4714597
57691873	57691895	18	-	27760321	HT1080	viability	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	-0.416460443976355	[531,414]	[84,202]	-2	hSpCas9	negative selection	4714598
57691939	57691961	18	+	27760321	HT1080	viability	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	0.6560970150301679	[512,400]	[263,311]	3	hSpCas9	negative selection	4714599
57701079	57701101	18	-	27760321	HT1080	viability	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4714600
57701272	57701294	18	+	27760321	HT1080	viability	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	2.230986312243682	[386,301]	[670,614]	9	hSpCas9	negative selection	4714601
57688491	57688513	18	+	27760321	HT29	viability after 7 days	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	0.15519613676832733	[640,499]	[949,982,543]	2	hSpCas9	negative selection	4798060
57691873	57691895	18	-	27760321	HT29	viability after 7 days	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	0.5163647062398935	[531,414]	[975,747,900]	7	hSpCas9	negative selection	4798061
57691939	57691961	18	+	27760321	HT29	viability after 7 days	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	0.6007920285417383	[512,400]	[916,775,979]	8	hSpCas9	negative selection	4798062
57701079	57701101	18	-	27760321	HT29	viability after 7 days	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4798063
57701272	57701294	18	+	27760321	HT29	viability after 7 days	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	0.23791216073907734	[386,301]	[525,652,391]	3	hSpCas9	negative selection	4798064
57688491	57688513	18	+	27760321	HT29	viability after 25 days	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	0.2770988791352814	[640,499]	[978,664,703]	3	hSpCas9	negative selection	4881523
57691873	57691895	18	-	27760321	HT29	viability after 25 days	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	0.20595472473876042	[531,414]	[837,395,623]	2	hSpCas9	negative selection	4881524
57691939	57691961	18	+	27760321	HT29	viability after 25 days	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	0.8582847623269525	[512,400]	[756,1114,982]	8	hSpCas9	negative selection	4881525
57701079	57701101	18	-	27760321	HT29	viability after 25 days	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4881526
57701272	57701294	18	+	27760321	HT29	viability after 25 days	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	0.12733097287056042	[386,301]	[386,415,495]	1	hSpCas9	negative selection	4881527
57688491	57688513	18	+	27760321	HT29	viability after 22 days	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	0.1021587003372314	[640,499]	[642,817,663]	1	hSpCas9	negative selection	4964986
57691873	57691895	18	-	27760321	HT29	viability after 22 days	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	0.6496488262319855	[531,414]	[1119,593,854]	7	hSpCas9	negative selection	4964987
57691939	57691961	18	+	27760321	HT29	viability after 22 days	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	1.0166830102512758	[512,400]	[1066,1287,849]	9	hSpCas9	negative selection	4964988
57701079	57701101	18	-	27760321	HT29	viability after 22 days	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4964989
57701272	57701294	18	+	27760321	HT29	viability after 22 days	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	0.28985496116818316	[386,301]	[247,424,796]	3	hSpCas9	negative selection	4964990
57688491	57688513	18	+	27760321	HT29	viability after 19 days	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	0.5899085304255326	[640,499]	[1147,623,1182]	6	hSpCas9	negative selection	5048449
57691873	57691895	18	-	27760321	HT29	viability after 19 days	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	0.1581962149453222	[531,414]	[1095,568,213]	1	hSpCas9	negative selection	5048450
57691939	57691961	18	+	27760321	HT29	viability after 19 days	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	1.0565796771751927	[512,400]	[867,1335,1035]	9	hSpCas9	negative selection	5048451
57701079	57701101	18	-	27760321	HT29	viability after 19 days	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5048452
57701272	57701294	18	+	27760321	HT29	viability after 19 days	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	0.3586497599265161	[386,301]	[405,731,371]	3	hSpCas9	negative selection	5048453
57688491	57688513	18	+	27760321	HT29	viability after 16 days	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	0.4701440809027516	[640,499]	[887,1023,736]	5	hSpCas9	negative selection	5131912
57691873	57691895	18	-	27760321	HT29	viability after 16 days	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	0.2845074739544744	[531,414]	[981,505,482]	3	hSpCas9	negative selection	5131913
57691939	57691961	18	+	27760321	HT29	viability after 16 days	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	0.6182519458913778	[512,400]	[672,901,765]	7	hSpCas9	negative selection	5131914
57701079	57701101	18	-	27760321	HT29	viability after 16 days	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5131915
57701272	57701294	18	+	27760321	HT29	viability after 16 days	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	0.5850310435534655	[386,301]	[539,646,541]	6	hSpCas9	negative selection	5131916
57688491	57688513	18	+	27760321	HT29	viability after 13 days	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	0.1911763136960124	[640,499]	[567,873,820]	2	hSpCas9	negative selection	5215375
57691873	57691895	18	-	27760321	HT29	viability after 13 days	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	0.5980723561381824	[531,414]	[1040,693,762]	7	hSpCas9	negative selection	5215376
57691939	57691961	18	+	27760321	HT29	viability after 13 days	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	0.6770607273383242	[512,400]	[705,913,918]	8	hSpCas9	negative selection	5215377
57701079	57701101	18	-	27760321	HT29	viability after 13 days	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5215378
57701272	57701294	18	+	27760321	HT29	viability after 13 days	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	0.1514240956307743	[386,301]	[411,481,437]	1	hSpCas9	negative selection	5215379
57688491	57688513	18	+	27760321	HT29	viability after 10 days	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	0.477609125262873	[640,499]	[1003,1101,874]	6	hSpCas9	negative selection	5298838
57691873	57691895	18	-	27760321	HT29	viability after 10 days	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	0.3948502222665631	[531,414]	[906,644,775]	5	hSpCas9	negative selection	5298839
57691939	57691961	18	+	27760321	HT29	viability after 10 days	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	0.9066273190547267	[512,400]	[921,1313,981]	9	hSpCas9	negative selection	5298840
57701079	57701101	18	-	27760321	HT29	viability after 10 days	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5298841
57701272	57701294	18	+	27760321	HT29	viability after 10 days	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	-0.28714885219954134	[386,301]	[474,228,349]	-4	hSpCas9	negative selection	5298842
57688491	57688513	18	+	27760321	MOLM13	viability	GACGAATCACTTCCACGCTAGG	ATP8B1	ENSG00000081923	0.2261657457502647	[714,640]	[474,422]	1	hSpCas9	negative selection	5382301
57691873	57691895	18	-	27760321	MOLM13	viability	ACGATACACCCTCCTACCGTGG	ATP8B1	ENSG00000081923	1.0530743184520872	[656,531]	[540,820]	7	hSpCas9	negative selection	5382302
57691939	57691961	18	+	27760321	MOLM13	viability	TCCCAATAAGCATGGCCGATGG	ATP8B1	ENSG00000081923	0.6154348420848391	[652,512]	[673,352]	4	hSpCas9	negative selection	5382303
57701079	57701101	18	-	27760321	MOLM13	viability	GCTCGCCATAAAATGGATAAGG	ATP8B1	ENSG00000081923	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5382304
57701272	57701294	18	+	27760321	MOLM13	viability	TAGTGTGGTGTACCAAGCCAGG	ATP8B1	ENSG00000081923	1.2460099827660431	[435,386]	[888,260]	8	hSpCas9	negative selection	5382305
57802624	57802647	18	+	27661255	K562	viability	GGAGCCAGCGGCATCCCCCAAGG	ATP8B1	ENSG00000081923	-0.0881173638514613	[532,475]	[421,343]	-3	dCas9-KRAB	negative selection	5464356
57802913	57802936	18	+	27661255	K562	viability	GGAGCGGCCAGGGAACCTGCAGG	ATP8B1	ENSG00000081923	0.12851404019533635	[693,758]	[695,579]	4	dCas9-KRAB	negative selection	5464357
57802671	57802694	18	-	27661255	K562	viability	GTAGCGACACACATGTCCGGGGG	ATP8B1	ENSG00000081923	0.10593036465478689	[1355,1552]	[1330,1175]	3	dCas9-KRAB	negative selection	5464358
57701085	57701108	18	-	27260156	BXPC3	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.2240919025901471	[164]	[166,188,285,163]	5	hSpCas9	negative selection	5529942
57701046	57701069	18	-	27260156	BXPC3	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.5925258097071829	[197]	[234,483,176,350]	9	hSpCas9	negative selection	5529943
57668141	57668164	18	+	27260156	BXPC3	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.1766638497038485	[553]	[561,646,702,721]	4	hSpCas9	negative selection	5552975
57697849	57697872	18	-	27260156	BXPC3	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.29547587479264414	[211]	[333,258,239,242]	6	hSpCas9	negative selection	5594226
57706504	57706527	18	-	27260156	BXPC3	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.007249008684349856	[626]	[719,615,621,638]	0	hSpCas9	negative selection	5594227
57668666	57668689	18	+	27260156	BXPC3	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.2794346911921475	[184]	[185,137,362,267]	6	hSpCas9	negative selection	5617233
57701085	57701108	18	-	27260156	A673	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.13904393519615432	[164]	[274,146,202,257]	3	hSpCas9	negative selection	5651193
57701046	57701069	18	-	27260156	A673	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.5072625056834186	[197]	[386,296,302,372]	9	hSpCas9	negative selection	5651194
57668141	57668164	18	+	27260156	A673	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.02233558176445019	[553]	[545,638,585,930]	0	hSpCas9	negative selection	5674226
57697849	57697872	18	-	27260156	A673	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.30298581534168423	[211]	[345,415,294,192]	7	hSpCas9	negative selection	5715477
57706504	57706527	18	-	27260156	A673	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.08722883846907131	[626]	[716,570,820,728]	-2	hSpCas9	negative selection	5715478
57668666	57668689	18	+	27260156	A673	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.2981964253670748	[184]	[302,274,297,215]	7	hSpCas9	negative selection	5738484
57701085	57701108	18	-	27260156	A375	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.37248792720311386	[164]	[271,91,303,300]	5	hSpCas9	negative selection	5772444
57701046	57701069	18	-	27260156	A375	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.7526095084074438	[197]	[429,419,399,319]	9	hSpCas9	negative selection	5772445
57668141	57668164	18	+	27260156	A375	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	-0.07647802763954542	[553]	[505,775,725,481]	-1	hSpCas9	negative selection	5795477
57697849	57697872	18	-	27260156	A375	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.37882586748107916	[211]	[297,404,226,362]	5	hSpCas9	negative selection	5836728
57706504	57706527	18	-	27260156	A375	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.4232790053480862	[626]	[1023,1013,1000,899]	6	hSpCas9	negative selection	5836729
57668666	57668689	18	+	27260156	A375	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.8195569204599469	[184]	[422,407,417,289]	9	hSpCas9	negative selection	5859735
57701085	57701108	18	-	27260156	COLO741	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.33532344880211795	[164]	[317,305,183]	7	hSpCas9	negative selection	5893695
57701046	57701069	18	-	27260156	COLO741	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.3937644112740809	[197]	[277,396,317]	7	hSpCas9	negative selection	5893696
57668141	57668164	18	+	27260156	COLO741	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	-0.37086908072564223	[553]	[655,558,442]	-7	hSpCas9	negative selection	5916728
57697849	57697872	18	-	27260156	COLO741	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	-0.0366109708470328	[211]	[306,248,240]	-1	hSpCas9	negative selection	5957979
57706504	57706527	18	-	27260156	COLO741	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.14552237797130607	[626]	[790,693,693]	-3	hSpCas9	negative selection	5957980
57668666	57668689	18	+	27260156	COLO741	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.45285799478897537	[184]	[339,345,287]	8	hSpCas9	negative selection	5980986
57701085	57701108	18	-	27260156	CAL120	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.14353793345584553	[164]	[271,125,287]	2	hSpCas9	negative selection	6014946
57701046	57701069	18	-	27260156	CAL120	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.1045566285317634	[197]	[284,267,244]	1	hSpCas9	negative selection	6014947
57668141	57668164	18	+	27260156	CAL120	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.05677089219276357	[553]	[820,878,470]	0	hSpCas9	negative selection	6037979
57697849	57697872	18	-	27260156	CAL120	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	-0.06153105418012328	[211]	[459,162,167]	-1	hSpCas9	negative selection	6079230
57706504	57706527	18	-	27260156	CAL120	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.028759925075916903	[626]	[757,839,783]	0	hSpCas9	negative selection	6079231
57668666	57668689	18	+	27260156	CAL120	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.5589822878301054	[184]	[488,274,276]	8	hSpCas9	negative selection	6102237
57701085	57701108	18	-	27260156	CADOES1	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.5136497700168672	[164]	[213,176,221,264]	8	hSpCas9	negative selection	6136197
57701046	57701069	18	-	27260156	CADOES1	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.4518704054104864	[197]	[164,386,179,276]	7	hSpCas9	negative selection	6136198
57668141	57668164	18	+	27260156	CADOES1	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	-0.07096414985721769	[553]	[561,390,713,286]	-1	hSpCas9	negative selection	6159230
57697849	57697872	18	-	27260156	CADOES1	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.4096858350600361	[211]	[292,196,332,222]	6	hSpCas9	negative selection	6200481
57706504	57706527	18	-	27260156	CADOES1	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.4268083807726691	[626]	[738,879,679,838]	7	hSpCas9	negative selection	6200482
57668666	57668689	18	+	27260156	CADOES1	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.8189037879392813	[184]	[575,246,171,214]	9	hSpCas9	negative selection	6223488
57701085	57701108	18	-	27260156	EWS502	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.2796745206339111	[164]	[231,205,104,307]	5	hSpCas9	negative selection	6257448
57701046	57701069	18	-	27260156	EWS502	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.5546072588145821	[197]	[360,265,241,359]	8	hSpCas9	negative selection	6257449
57668141	57668164	18	+	27260156	EWS502	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.11915174168771228	[553]	[623,618,677,627]	2	hSpCas9	negative selection	6280481
57697849	57697872	18	-	27260156	EWS502	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	-0.0823881655855414	[211]	[194,209,215,229]	-1	hSpCas9	negative selection	6321732
57706504	57706527	18	-	27260156	EWS502	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.308695460999398	[626]	[1003,768,621,872]	5	hSpCas9	negative selection	6321733
57668666	57668689	18	+	27260156	EWS502	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.18539899170735086	[184]	[199,205,272,214]	3	hSpCas9	negative selection	6344739
57701085	57701108	18	-	27260156	EW8	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.28075150290049833	[164]	[217,185,94,167]	5	hSpCas9	negative selection	6378699
57701046	57701069	18	-	27260156	EW8	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.25957652933419983	[197]	[345,143,184,110]	5	hSpCas9	negative selection	6378700
57668141	57668164	18	+	27260156	EW8	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.17455854001584484	[553]	[584,591,445,421]	3	hSpCas9	negative selection	6401732
57697849	57697872	18	-	27260156	EW8	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.3079348567096962	[211]	[383,201,118,179]	5	hSpCas9	negative selection	6442983
57706504	57706527	18	-	27260156	EW8	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.03402480925974799	[626]	[502,452,514,509]	0	hSpCas9	negative selection	6442984
57668666	57668689	18	+	27260156	EW8	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.797643287174735	[184]	[305,228,293,211]	9	hSpCas9	negative selection	6465990
57701085	57701108	18	-	27260156	CORL105	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.5185959443980059	[164]	[383,171,435,145]	8	hSpCas9	negative selection	6499950
57701046	57701069	18	-	27260156	CORL105	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.5277596255599721	[197]	[330,263,311,426]	8	hSpCas9	negative selection	6499951
57668141	57668164	18	+	27260156	CORL105	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.09521105788538323	[553]	[744,692,717,620]	1	hSpCas9	negative selection	6522983
57697849	57697872	18	-	27260156	CORL105	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.06978314449174117	[211]	[270,286,198,274]	1	hSpCas9	negative selection	6564234
57706504	57706527	18	-	27260156	CORL105	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.21848340200105526	[626]	[845,693,1178,750]	4	hSpCas9	negative selection	6564235
57668666	57668689	18	+	27260156	CORL105	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.4883873465734965	[184]	[355,228,363,278]	8	hSpCas9	negative selection	6587241
57701085	57701108	18	-	27260156	HS294T	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	-0.08433531909893754	[164]	[41,100,46,48]	-1	hSpCas9	negative selection	6621201
57701046	57701069	18	-	27260156	HS294T	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.45339218181999297	[197]	[83,138,90,105]	6	hSpCas9	negative selection	6621202
57668141	57668164	18	+	27260156	HS294T	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.012795195672986565	[553]	[205,153,209,312]	0	hSpCas9	negative selection	6644234
57697849	57697872	18	-	27260156	HS294T	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.5598249731680808	[211]	[172,77,98,130]	7	hSpCas9	negative selection	6685485
57706504	57706527	18	-	27260156	HS294T	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.07460102857782563	[626]	[313,177,229,183]	-1	hSpCas9	negative selection	6685486
57668666	57668689	18	+	27260156	HS294T	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.5069440826557381	[184]	[136,82,93,86]	6	hSpCas9	negative selection	6708492
57701085	57701108	18	-	27260156	HCC44	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.28479209510983505	[164]	[260,191,340,143]	4	hSpCas9	negative selection	6742452
57701046	57701069	18	-	27260156	HCC44	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.4202440730987702	[197]	[241,279,337,338]	7	hSpCas9	negative selection	6742453
57668141	57668164	18	+	27260156	HCC44	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.3563052454129201	[553]	[884,776,838,720]	6	hSpCas9	negative selection	6765485
57697849	57697872	18	-	27260156	HCC44	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.030476461075489514	[211]	[232,221,246,276]	0	hSpCas9	negative selection	6806736
57706504	57706527	18	-	27260156	HCC44	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.0033438814988338006	[626]	[812,818,640,538]	0	hSpCas9	negative selection	6806737
57668666	57668689	18	+	27260156	HCC44	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.4500754547144201	[184]	[297,146,344,378]	7	hSpCas9	negative selection	6829743
57701085	57701108	18	-	27260156	G402	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	-0.410432918098548	[164]	[86,169,143,193]	-5	hSpCas9	negative selection	6863703
57701046	57701069	18	-	27260156	G402	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	1.0864721088579092	[197]	[232,776,711,312]	9	hSpCas9	negative selection	6863704
57668141	57668164	18	+	27260156	G402	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	-0.16480577864511908	[553]	[532,673,789,415]	-2	hSpCas9	negative selection	6886736
57697849	57697872	18	-	27260156	G402	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	-0.2023978505546722	[211]	[391,159,209,159]	-3	hSpCas9	negative selection	6927987
57706504	57706527	18	-	27260156	G402	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.7022383839017603	[626]	[1257,1845,955,964]	8	hSpCas9	negative selection	6927988
57668666	57668689	18	+	27260156	G402	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.6222555335483237	[184]	[263,368,529,220]	7	hSpCas9	negative selection	6950994
57701085	57701108	18	-	27260156	L33	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.3278624860474082	[164]	[176,81,97,294]	7	hSpCas9	negative selection	6984954
57701046	57701069	18	-	27260156	L33	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.7432276779132893	[197]	[199,153,241,367]	9	hSpCas9	negative selection	6984955
57668141	57668164	18	+	27260156	L33	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.07838065866342572	[553]	[594,252,314,624]	1	hSpCas9	negative selection	7007987
57697849	57697872	18	-	27260156	L33	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.2178101866647928	[211]	[174,109,167,276]	5	hSpCas9	negative selection	7049238
57706504	57706527	18	-	27260156	L33	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.020388428176175366	[626]	[720,234,422,503]	0	hSpCas9	negative selection	7049239
57668666	57668689	18	+	27260156	L33	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.15215920629280255	[184]	[187,104,143,149]	3	hSpCas9	negative selection	7072245
57701085	57701108	18	-	27260156	K562	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	1.0114439063671212	[164]	[476,341,140,242]	9	hSpCas9	negative selection	7106205
57701046	57701069	18	-	27260156	K562	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.20536455142054355	[197]	[138,405,227,58]	2	hSpCas9	negative selection	7106206
57668141	57668164	18	+	27260156	K562	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.0547060798690048	[553]	[286,516,722,496]	0	hSpCas9	negative selection	7129238
57697849	57697872	18	-	27260156	K562	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	-0.0017165408157386874	[211]	[157,148,200,232]	0	hSpCas9	negative selection	7170489
57706504	57706527	18	-	27260156	K562	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.2726150946780514	[626]	[735,549,494,878]	3	hSpCas9	negative selection	7170490
57668666	57668689	18	+	27260156	K562	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.04014142927939646	[184]	[144,171,264,98]	0	hSpCas9	negative selection	7193496
57701085	57701108	18	-	27260156	HT29	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.22789101845574788	[164]	[289,289,249,129]	4	hSpCas9	negative selection	7227456
57701046	57701069	18	-	27260156	HT29	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.47712174532495355	[197]	[432,391,251,279]	8	hSpCas9	negative selection	7227457
57668141	57668164	18	+	27260156	HT29	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.19196047074312186	[553]	[759,758,826,728]	4	hSpCas9	negative selection	7250489
57697849	57697872	18	-	27260156	HT29	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.6813867282833338	[211]	[451,316,481,395]	9	hSpCas9	negative selection	7291740
57706504	57706527	18	-	27260156	HT29	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.2437288287617287	[626]	[923,808,737,1100]	5	hSpCas9	negative selection	7291741
57668666	57668689	18	+	27260156	HT29	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.2906525577939003	[184]	[310,350,236,215]	5	hSpCas9	negative selection	7314747
57701085	57701108	18	-	27260156	MHHES1	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.26094161099759106	[164]	[216,259,378,69]	5	hSpCas9	negative selection	7348707
57701046	57701069	18	-	27260156	MHHES1	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.827009454836976	[197]	[347,479,464,304]	9	hSpCas9	negative selection	7348708
57668141	57668164	18	+	27260156	MHHES1	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.020866798841132544	[553]	[522,812,735,485]	0	hSpCas9	negative selection	7371740
57697849	57697872	18	-	27260156	MHHES1	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.3608828816747759	[211]	[260,458,284,239]	6	hSpCas9	negative selection	7412991
57706504	57706527	18	-	27260156	MHHES1	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.40755779836832	[626]	[885,1015,1006,840]	7	hSpCas9	negative selection	7412992
57668666	57668689	18	+	27260156	MHHES1	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.2504285447593242	[184]	[260,289,307,154]	4	hSpCas9	negative selection	7435998
57701085	57701108	18	-	27260156	MEWO	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	-0.3421480976723532	[164]	[114,118,129]	-6	hSpCas9	negative selection	7469958
57701046	57701069	18	-	27260156	MEWO	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.4850037113518908	[197]	[198,269,296]	8	hSpCas9	negative selection	7469959
57668141	57668164	18	+	27260156	MEWO	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.2945360652706397	[553]	[805,620,512]	6	hSpCas9	negative selection	7492991
57697849	57697872	18	-	27260156	MEWO	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.007382908642909136	[211]	[182,169,241]	0	hSpCas9	negative selection	7534242
57706504	57706527	18	-	27260156	MEWO	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.05014298187312011	[626]	[870,470,416]	-1	hSpCas9	negative selection	7534243
57668666	57668689	18	+	27260156	MEWO	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.4385402121580003	[184]	[389,182,160]	8	hSpCas9	negative selection	7557249
57701085	57701108	18	-	27260156	LNCAPCLONEFGC	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.31028505747288393	[164]	[170,178,212,182]	5	hSpCas9	negative selection	7591209
57701046	57701069	18	-	27260156	LNCAPCLONEFGC	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.6294569476568297	[197]	[307,185,498,154]	8	hSpCas9	negative selection	7591210
57668141	57668164	18	+	27260156	LNCAPCLONEFGC	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	-0.22433281150037573	[553]	[447,342,480,458]	-4	hSpCas9	negative selection	7614242
57697849	57697872	18	-	27260156	LNCAPCLONEFGC	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.41130423296374774	[211]	[235,263,253,266]	6	hSpCas9	negative selection	7655493
57706504	57706527	18	-	27260156	LNCAPCLONEFGC	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.1876509160651198	[626]	[806,577,636,564]	3	hSpCas9	negative selection	7655494
57668666	57668689	18	+	27260156	LNCAPCLONEFGC	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.7559292090843702	[184]	[287,276,288,278]	9	hSpCas9	negative selection	7678500
57701085	57701108	18	-	27260156	PANC0327	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	-0.7282956489510528	[164]	[74,86,113,76]	-7	hSpCas9	negative selection	7712460
57701046	57701069	18	-	27260156	PANC0327	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.8381797954787604	[197]	[444,286,315,223]	9	hSpCas9	negative selection	7712461
57668141	57668164	18	+	27260156	PANC0327	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.09436455286893539	[553]	[672,412,520,520]	1	hSpCas9	negative selection	7735493
57697849	57697872	18	-	27260156	PANC0327	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	-0.31268963537452876	[211]	[178,139,63,226]	-4	hSpCas9	negative selection	7776744
57706504	57706527	18	-	27260156	PANC0327	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.34009387857601997	[626]	[782,501,950,616]	5	hSpCas9	negative selection	7776745
57668666	57668689	18	+	27260156	PANC0327	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	1.2084266032458748	[184]	[533,197,383,438]	9	hSpCas9	negative selection	7799751
57701085	57701108	18	-	27260156	NCIH2009	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.11674309972283115	[164]	[300,224,233]	1	hSpCas9	negative selection	7833711
57701046	57701069	18	-	27260156	NCIH2009	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.8179770879775552	[197]	[562,439,474]	9	hSpCas9	negative selection	7833712
57668141	57668164	18	+	27260156	NCIH2009	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.6338245987432948	[553]	[1147,1287,1152]	8	hSpCas9	negative selection	7856744
57697849	57697872	18	-	27260156	NCIH2009	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.540353025503705	[211]	[683,299,359]	7	hSpCas9	negative selection	7897995
57706504	57706527	18	-	27260156	NCIH2009	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.11940095656581057	[626]	[941,1022,884]	1	hSpCas9	negative selection	7897996
57668666	57668689	18	+	27260156	NCIH2009	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.5692507241410129	[184]	[440,341,378]	7	hSpCas9	negative selection	7921002
57701085	57701108	18	-	27260156	NCIH1373	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.7904292416388525	[164]	[174,266,218,162]	7	hSpCas9	negative selection	7954962
57701046	57701069	18	-	27260156	NCIH1373	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.9345707721422594	[197]	[382,461,657,41]	8	hSpCas9	negative selection	7954963
57668141	57668164	18	+	27260156	NCIH1373	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.565234507803365	[553]	[1424,523,1380,110]	5	hSpCas9	negative selection	7977995
57697849	57697872	18	-	27260156	NCIH1373	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	1.1545059165720721	[211]	[648,394,540,147]	9	hSpCas9	negative selection	8019246
57706504	57706527	18	-	27260156	NCIH1373	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.7604784127813407	[626]	[1473,1538,836,236]	7	hSpCas9	negative selection	8019247
57668666	57668689	18	+	27260156	NCIH1373	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.7383109152441077	[184]	[372,209,356,122]	7	hSpCas9	negative selection	8042253
57701085	57701108	18	-	27260156	PATU8902	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	-0.26154414159579864	[164]	[352,90,193,114]	-3	hSpCas9	negative selection	8076213
57701046	57701069	18	-	27260156	PATU8902	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	1.2444455795520788	[197]	[507,697,426,1087]	9	hSpCas9	negative selection	8076214
57668141	57668164	18	+	27260156	PATU8902	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.5089607456989531	[553]	[1222,698,1110,1376]	5	hSpCas9	negative selection	8099246
57697849	57697872	18	-	27260156	PATU8902	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	1.277150746381027	[211]	[655,223,1266,544]	9	hSpCas9	negative selection	8140497
57706504	57706527	18	-	27260156	PATU8902	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.8116027640910664	[626]	[1768,1521,1305,1582]	8	hSpCas9	negative selection	8140498
57668666	57668689	18	+	27260156	PATU8902	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.48871455844948153	[184]	[615,222,346,242]	5	hSpCas9	negative selection	8163504
57701085	57701108	18	-	27260156	PANC1	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.34705675943536884	[164]	[158,190,125,234]	5	hSpCas9	negative selection	8197464
57701046	57701069	18	-	27260156	PANC1	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	1.1191842082994832	[197]	[292,352,451,371]	9	hSpCas9	negative selection	8197465
57668141	57668164	18	+	27260156	PANC1	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	-0.2073253101639436	[553]	[373,559,430,322]	-3	hSpCas9	negative selection	8220497
57697849	57697872	18	-	27260156	PANC1	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.34315371571828646	[211]	[258,146,321,182]	5	hSpCas9	negative selection	8261748
57706504	57706527	18	-	27260156	PANC1	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.3345038283954122	[626]	[837,832,674,428]	5	hSpCas9	negative selection	8261749
57668666	57668689	18	+	27260156	PANC1	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.48447724011891335	[184]	[358,335,112,114]	7	hSpCas9	negative selection	8284755
57701085	57701108	18	-	27260156	PANC0813	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	-0.013242894572222719	[164]	[177,237,151,197]	0	hSpCas9	negative selection	8318715
57701046	57701069	18	-	27260156	PANC0813	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.4625268856786805	[197]	[358,369,311,247]	7	hSpCas9	negative selection	8318716
57668141	57668164	18	+	27260156	PANC0813	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.19782897895890802	[553]	[680,764,760,769]	3	hSpCas9	negative selection	8341748
57697849	57697872	18	-	27260156	PANC0813	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.4778693518297549	[211]	[385,378,261,361]	7	hSpCas9	negative selection	8382999
57706504	57706527	18	-	27260156	PANC0813	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.10288642263196429	[626]	[795,770,684,903]	1	hSpCas9	negative selection	8383000
57668666	57668689	18	+	27260156	PANC0813	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.11493287440447841	[184]	[381,142,170,256]	2	hSpCas9	negative selection	8406006
57701085	57701108	18	-	27260156	RDES	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.22593219543087217	[164]	[219,172,230,268]	3	hSpCas9	negative selection	8439966
57701046	57701069	18	-	27260156	RDES	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.32763805857036943	[197]	[235,310,311,283]	5	hSpCas9	negative selection	8439967
57668141	57668164	18	+	27260156	RDES	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	-0.1901436666175818	[553]	[479,506,569,703]	-3	hSpCas9	negative selection	8462999
57697849	57697872	18	-	27260156	RDES	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.35489710347359193	[211]	[215,276,371,415]	5	hSpCas9	negative selection	8504250
57706504	57706527	18	-	27260156	RDES	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.0803016400331556	[626]	[606,813,747,906]	1	hSpCas9	negative selection	8504251
57668666	57668689	18	+	27260156	RDES	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.786046569578225	[184]	[347,427,347,320]	9	hSpCas9	negative selection	8527257
57701085	57701108	18	-	27260156	PC3	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	-0.01273527653509432	[164]	[96,165,275,170]	0	hSpCas9	negative selection	8561217
57701046	57701069	18	-	27260156	PC3	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.09715678342691669	[197]	[121,144,280,353]	2	hSpCas9	negative selection	8561218
57668141	57668164	18	+	27260156	PC3	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.1608306191163462	[553]	[526,617,819,538]	3	hSpCas9	negative selection	8584250
57697849	57697872	18	-	27260156	PC3	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.07802166235751251	[211]	[157,225,313,233]	1	hSpCas9	negative selection	8625501
57706504	57706527	18	-	27260156	PC3	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.08464859933343005	[626]	[329,564,1128,607]	-2	hSpCas9	negative selection	8625502
57668666	57668689	18	+	27260156	PC3	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.13884327465397672	[184]	[150,234,218,210]	3	hSpCas9	negative selection	8648508
57701085	57701108	18	-	27260156	PATU8988T	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.4317813000665829	[164]	[176,372,193,123]	7	hSpCas9	negative selection	8682468
57701046	57701069	18	-	27260156	PATU8988T	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.40886249204313396	[197]	[400,184,206,213]	7	hSpCas9	negative selection	8682469
57668141	57668164	18	+	27260156	PATU8988T	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.017279687762465717	[553]	[440,536,372,841]	0	hSpCas9	negative selection	8705501
57697849	57697872	18	-	27260156	PATU8988T	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	-0.014387956270518476	[211]	[173,282,250,101]	0	hSpCas9	negative selection	8746752
57706504	57706527	18	-	27260156	PATU8988T	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.07076594185672558	[626]	[653,672,586,386]	-1	hSpCas9	negative selection	8746753
57668666	57668689	18	+	27260156	PATU8988T	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.01736667078200016	[184]	[221,191,163,143]	0	hSpCas9	negative selection	8769759
57701085	57701108	18	-	27260156	T47D	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.12777627189487673	[164]	[214,199,191,234]	2	hSpCas9	negative selection	8803719
57701046	57701069	18	-	27260156	T47D	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.5851250326337918	[197]	[375,324,320,364]	9	hSpCas9	negative selection	8803720
57668141	57668164	18	+	27260156	T47D	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	-0.010790207349290926	[553]	[683,572,644,666]	0	hSpCas9	negative selection	8826752
57697849	57697872	18	-	27260156	T47D	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.29332610202399356	[211]	[314,297,317,278]	6	hSpCas9	negative selection	8868003
57706504	57706527	18	-	27260156	T47D	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.2140744742329585	[626]	[997,813,717,864]	4	hSpCas9	negative selection	8868004
57668666	57668689	18	+	27260156	T47D	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.3030194013604113	[184]	[296,216,257,296]	6	hSpCas9	negative selection	8891010
57701085	57701108	18	-	27260156	SU8686	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.5173539982909466	[164]	[247,193,239,260]	8	hSpCas9	negative selection	8924970
57701046	57701069	18	-	27260156	SU8686	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.7019741705783752	[197]	[304,291,292,402]	9	hSpCas9	negative selection	8924971
57668141	57668164	18	+	27260156	SU8686	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.26643623937238925	[553]	[621,635,536,882]	4	hSpCas9	negative selection	8948003
57697849	57697872	18	-	27260156	SU8686	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.24990244929456507	[211]	[203,217,273,323]	4	hSpCas9	negative selection	8989254
57706504	57706527	18	-	27260156	SU8686	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.017634848278272053	[626]	[534,507,778,738]	0	hSpCas9	negative selection	8989255
57668666	57668689	18	+	27260156	SU8686	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	-0.05181166025048611	[184]	[112,187,210,205]	-1	hSpCas9	negative selection	9012261
57701085	57701108	18	-	27260156	SKES1	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.2065422492663831	[164]	[168,288,164,148]	4	hSpCas9	negative selection	9046221
57701046	57701069	18	-	27260156	SKES1	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.44324305658462726	[197]	[297,290,254,237]	8	hSpCas9	negative selection	9046222
57668141	57668164	18	+	27260156	SKES1	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.2165938874615266	[553]	[749,694,715,444]	4	hSpCas9	negative selection	9069254
57697849	57697872	18	-	27260156	SKES1	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	-0.04514594442025599	[211]	[178,238,181,216]	-1	hSpCas9	negative selection	9110505
57706504	57706527	18	-	27260156	SKES1	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.21855812818805598	[626]	[626,535,501,496]	-5	hSpCas9	negative selection	9110506
57668666	57668689	18	+	27260156	SKES1	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.4872454660094019	[184]	[291,212,256,267]	8	hSpCas9	negative selection	9133512
57701085	57701108	18	-	27260156	TOV112D	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.11852821763052046	[164]	[128,345,132,146]	2	hSpCas9	negative selection	9167472
57701046	57701069	18	-	27260156	TOV112D	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.1859291440895683	[197]	[205,401,119,215]	3	hSpCas9	negative selection	9167473
57668141	57668164	18	+	27260156	TOV112D	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	0.06647426271429899	[553]	[665,704,524,467]	1	hSpCas9	negative selection	9190505
57697849	57697872	18	-	27260156	TOV112D	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.48848055651087674	[211]	[256,454,205,307]	8	hSpCas9	negative selection	9231756
57706504	57706527	18	-	27260156	TOV112D	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	-0.2856907423832389	[626]	[605,725,405,384]	-5	hSpCas9	negative selection	9231757
57668666	57668689	18	+	27260156	TOV112D	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.24555629475915008	[184]	[238,247,219,180]	5	hSpCas9	negative selection	9254763
57701085	57701108	18	-	27260156	TC71	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.457531240121553	[164]	[247,294,228,196]	9	hSpCas9	negative selection	9288723
57701046	57701069	18	-	27260156	TC71	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.3824156176470028	[197]	[185,334,245,346]	8	hSpCas9	negative selection	9288724
57668141	57668164	18	+	27260156	TC71	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	-0.024874537776525568	[553]	[613,552,474,702]	0	hSpCas9	negative selection	9311756
57697849	57697872	18	-	27260156	TC71	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.1950891029141133	[211]	[224,285,200,335]	5	hSpCas9	negative selection	9353007
57706504	57706527	18	-	27260156	TC71	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.06944951643058367	[626]	[628,712,667,820]	1	hSpCas9	negative selection	9353008
57668666	57668689	18	+	27260156	TC71	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.09813305136648709	[184]	[165,199,241,242]	2	hSpCas9	negative selection	9376014
57701085	57701108	18	-	27260156	TC32	viability	TCTCAAGGCTCGCCATAAAATGG	ATP8B1	ENSG00000081923	0.09271685806881158	[164]	[203,78,247,162]	1	hSpCas9	negative selection	9409974
57701046	57701069	18	-	27260156	TC32	viability	TAGGACGTGTGAAGTCATTAAGG	ATP8B1	ENSG00000081923	0.30384057723381797	[197]	[218,103,397,265]	5	hSpCas9	negative selection	9409975
57668141	57668164	18	+	27260156	TC32	viability	TCAGGACGGGAACCCACGTCTGG	ATP8B1	ENSG00000081923	-0.08976953106834895	[553]	[474,277,720,582]	-1	hSpCas9	negative selection	9433007
57697849	57697872	18	-	27260156	TC32	viability	TTAGGTTCAAAGTTGCTAAGTGG	ATP8B1	ENSG00000081923	0.23189098518472073	[211]	[155,234,361,197]	4	hSpCas9	negative selection	9474258
57706504	57706527	18	-	27260156	TC32	viability	CACAAAATTCTTGTGTATTAAGG	ATP8B1	ENSG00000081923	0.22754439233589357	[626]	[621,562,741,865]	4	hSpCas9	negative selection	9474259
57668666	57668689	18	+	27260156	TC32	viability	GGCCAATGGCCAGTGTTAACAGG	ATP8B1	ENSG00000081923	0.3834607689127745	[184]	[252,181,319,163]	6	hSpCas9	negative selection	9497265
57688503	57688526	18	-	27869803	HPAFII	viability after 27 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.694444751142326	[289]	[303,198,NaN]	5	hSpCas9	negative selection	9564813
57691864	57691887	18	+	27869803	HPAFII	viability after 27 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.0531113364595624	[205]	[89,130,NaN]	0	hSpCas9	negative selection	9564814
57695188	57695211	18	-	27869803	HPAFII	viability after 27 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	1.0531113364595623	[100]	[35,171,NaN]	8	hSpCas9	negative selection	9564815
57701244	57701267	18	+	27869803	HPAFII	viability after 27 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.7035191110730643	[497]	[289,539,NaN]	6	hSpCas9	negative selection	9564816
57704554	57704577	18	+	27869803	HPAFII	viability after 27 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	1.0328159951250921	[172]	[136,226,NaN]	8	hSpCas9	negative selection	9564817
57731626	57731649	18	-	27869803	HPAFII	viability after 27 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.538313637126995	[611]	[271,629,NaN]	4	hSpCas9	negative selection	9564818
57688503	57688526	18	-	27869803	HPAFII	viability after 15 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.5644852040348426	[289]	[656,338,NaN]	6	hSpCas9	negative selection	9647262
57691864	57691887	18	+	27869803	HPAFII	viability after 15 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	-0.28899627885883183	[205]	[232,148,NaN]	-3	hSpCas9	negative selection	9647263
57695188	57695211	18	-	27869803	HPAFII	viability after 15 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	0.6202205821099306	[100]	[164,167,NaN]	7	hSpCas9	negative selection	9647264
57701244	57701267	18	+	27869803	HPAFII	viability after 15 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.42493198553510747	[497]	[876,619,NaN]	5	hSpCas9	negative selection	9647265
57704554	57704577	18	+	27869803	HPAFII	viability after 15 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	0.32509126641126396	[172]	[272,207,NaN]	4	hSpCas9	negative selection	9647266
57731626	57731649	18	-	27869803	HPAFII	viability after 15 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.385300553254571	[611]	[736,934,NaN]	4	hSpCas9	negative selection	9647267
57688503	57688526	18	-	27869803	ASPC1	viability after 36 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.5646069000367635	[973]	[714,402,427]	5	hSpCas9	negative selection	9729711
57691864	57691887	18	+	27869803	ASPC1	viability after 36 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.22213127804919752	[428]	[43,163,272]	2	hSpCas9	negative selection	9729712
57695188	57695211	18	-	27869803	ASPC1	viability after 36 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	1.0962103532435352	[317]	[110,24,491]	8	hSpCas9	negative selection	9729713
57701244	57701267	18	+	27869803	ASPC1	viability after 36 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	1.047526632342061	[1054]	[913,468,877]	8	hSpCas9	negative selection	9729714
57704554	57704577	18	+	27869803	ASPC1	viability after 36 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	-0.24561645691093906	[583]	[362,161,43]	-3	hSpCas9	negative selection	9729715
57731626	57731649	18	-	27869803	ASPC1	viability after 36 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.3782456417664275	[1315]	[698,502,593]	4	hSpCas9	negative selection	9729716
57688503	57688526	18	-	27869803	PATU8988S	viability after 35 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.8559484542475962	[823]	[670,529,NaN]	8	hSpCas9	negative selection	9812160
57691864	57691887	18	+	27869803	PATU8988S	viability after 35 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.7245641872380489	[350]	[273,192,NaN]	7	hSpCas9	negative selection	9812161
57695188	57695211	18	-	27869803	PATU8988S	viability after 35 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	1.8003797303848894	[282]	[396,396,NaN]	9	hSpCas9	negative selection	9812162
57701244	57701267	18	+	27869803	PATU8988S	viability after 35 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	1.821490853508981	[1072]	[1711,1341,NaN]	9	hSpCas9	negative selection	9812163
57704554	57704577	18	+	27869803	PATU8988S	viability after 35 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	1.3910520351833133	[371]	[366,418,NaN]	9	hSpCas9	negative selection	9812164
57731626	57731649	18	-	27869803	PATU8988S	viability after 35 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.5213814888388111	[1347]	[888,668,NaN]	6	hSpCas9	negative selection	9812165
57688503	57688526	18	-	27869803	PATU8988S	viability after 31 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	0.5279919552196283	[823]	[493,447,NaN]	6	hSpCas9	negative selection	9894609
57691864	57691887	18	+	27869803	PATU8988S	viability after 31 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	0.2764840742204432	[350]	[187,145,NaN]	3	hSpCas9	negative selection	9894610
57695188	57695211	18	-	27869803	PATU8988S	viability after 31 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	1.1786106626409178	[282]	[221,297,NaN]	9	hSpCas9	negative selection	9894611
57701244	57701267	18	+	27869803	PATU8988S	viability after 31 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	1.4439784342904747	[1072]	[1050,1307,NaN]	9	hSpCas9	negative selection	9894612
57704554	57704577	18	+	27869803	PATU8988S	viability after 31 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	1.1532141722899372	[371]	[255,423,NaN]	9	hSpCas9	negative selection	9894613
57731626	57731649	18	-	27869803	PATU8988S	viability after 31 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.24050610262638505	[1347]	[700,550,NaN]	3	hSpCas9	negative selection	9894614
57688503	57688526	18	-	27869803	HPAFII	viability after 35 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	1.247251576671318	[289]	[435,249,NaN]	8	hSpCas9	negative selection	9977058
57691864	57691887	18	+	27869803	HPAFII	viability after 35 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	-0.18668813078635632	[205]	[53,133,NaN]	-1	hSpCas9	negative selection	9977059
57695188	57695211	18	-	27869803	HPAFII	viability after 35 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	1.4586483313715812	[100]	[29,264,NaN]	8	hSpCas9	negative selection	9977060
57701244	57701267	18	+	27869803	HPAFII	viability after 35 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.7723335065628953	[497]	[122,776,NaN]	5	hSpCas9	negative selection	9977061
57704554	57704577	18	+	27869803	HPAFII	viability after 35 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	0.8837507705733841	[172]	[67,266,NaN]	6	hSpCas9	negative selection	9977062
57731626	57731649	18	-	27869803	HPAFII	viability after 35 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.8827066111354889	[611]	[384,780,NaN]	6	hSpCas9	negative selection	9977063
57688503	57688526	18	-	27869803	HPAFII	viability after 31 days	AATCTTCTGTCTTCCTAGCGTGG	ATP8B1	ENSG00000081923	1.2962874347674722	[289]	[437,357,NaN]	8	hSpCas9	negative selection	10059507
57691864	57691887	18	+	27869803	HPAFII	viability after 31 days	ATGAGGAATCCACGGTAGGAGGG	ATP8B1	ENSG00000081923	-0.3483954487687829	[205]	[52,131,NaN]	-2	hSpCas9	negative selection	10059508
57695188	57695211	18	-	27869803	HPAFII	viability after 31 days	AGGAACACCGATTTCTGCCACGG	ATP8B1	ENSG00000081923	1.164898857150017	[100]	[50,209,NaN]	8	hSpCas9	negative selection	10059509
57701244	57701267	18	+	27869803	HPAFII	viability after 31 days	TGACGCCCAGCACCACAAGCAGG	ATP8B1	ENSG00000081923	0.5835361106765307	[497]	[235,617,NaN]	4	hSpCas9	negative selection	10059510
57704554	57704577	18	+	27869803	HPAFII	viability after 31 days	CCTGTAAGATAAGAAGAGCCAGG	ATP8B1	ENSG00000081923	0.6759971567516304	[172]	[101,212,NaN]	5	hSpCas9	negative selection	10059511
57731626	57731649	18	-	27869803	HPAFII	viability after 31 days	AACCGGGAGCCATTCAGAAAAGG	ATP8B1	ENSG00000081923	0.7631233055412292	[611]	[446,730,NaN]	5	hSpCas9	negative selection	10059512
57701246	57701269	18	+	28162770	P31FUJ	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.22691890856338803	[452]	[622]	2	hSpCas9	negative selection	10116166
57652566	57652589	18	-	28162770	P31FUJ	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	0.6464456361250112	[273]	[503]	7	hSpCas9	negative selection	10116167
57661334	57661357	18	-	28162770	P31FUJ	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	0.40679555288362346	[94]	[147]	4	hSpCas9	negative selection	10116168
57731697	57731720	18	-	28162770	P31FUJ	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.5197009588080203	[313]	[528]	6	hSpCas9	negative selection	10116169
57697628	57697651	18	+	28162770	P31FUJ	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.10778534570458409	[168]	[213]	1	hSpCas9	negative selection	10116170
57685089	57685112	18	+	28162770	P31FUJ	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.3886861723318915	[324]	[499]	4	hSpCas9	negative selection	10116171
57684048	57684071	18	-	28162770	P31FUJ	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	-0.31670346202332383	[176]	[166]	-3	hSpCas9	negative selection	10116172
57671470	57671493	18	-	28162770	P31FUJ	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	-0.1052141495295264	[291]	[318]	-1	hSpCas9	negative selection	10116173
57662571	57662594	18	-	28162770	P31FUJ	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	0.025265948526065785	[96]	[115]	0	hSpCas9	negative selection	10116174
57662505	57662528	18	+	28162770	P31FUJ	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	0.05591884508306483	[166]	[203]	0	hSpCas9	negative selection	10116175
57701246	57701269	18	+	28162770	TF1	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	NaN	[NaN]	[925]	1	hSpCas9	negative selection	10285532
57652566	57652589	18	-	28162770	TF1	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	NaN	[NaN]	[166]	1	hSpCas9	negative selection	10285533
57661334	57661357	18	-	28162770	TF1	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10285534
57731697	57731720	18	-	28162770	TF1	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	NaN	[NaN]	[225]	1	hSpCas9	negative selection	10285535
57697628	57697651	18	+	28162770	TF1	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	NaN	[NaN]	[462]	1	hSpCas9	negative selection	10285536
57685089	57685112	18	+	28162770	TF1	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	NaN	[NaN]	[325]	1	hSpCas9	negative selection	10285537
57684048	57684071	18	-	28162770	TF1	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	NaN	[NaN]	[200]	1	hSpCas9	negative selection	10285538
57671470	57671493	18	-	28162770	TF1	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	NaN	[NaN]	[395]	1	hSpCas9	negative selection	10285539
57662571	57662594	18	-	28162770	TF1	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	NaN	[NaN]	[80]	1	hSpCas9	negative selection	10285540
57662505	57662528	18	+	28162770	TF1	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	NaN	[NaN]	[171]	1	hSpCas9	negative selection	10285541
57701246	57701269	18	+	28162770	SKM1	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.7357759733729201	[124]	[367]	7	hSpCas9	negative selection	10454898
57652566	57652589	18	-	28162770	SKM1	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	-0.3332545125601525	[61]	[86]	-3	hSpCas9	negative selection	10454899
57661334	57661357	18	-	28162770	SKM1	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	0.13219461236486985	[31]	[61]	1	hSpCas9	negative selection	10454900
57731697	57731720	18	-	28162770	SKM1	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	-0.5088438127623752	[98]	[122]	-4	hSpCas9	negative selection	10454901
57697628	57697651	18	+	28162770	SKM1	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	-0.167137184070693	[46]	[73]	-1	hSpCas9	negative selection	10454902
57685089	57685112	18	+	28162770	SKM1	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.34603619387604156	[84]	[190]	3	hSpCas9	negative selection	10454903
57684048	57684071	18	-	28162770	SKM1	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	0.7473639476481321	[30]	[91]	7	hSpCas9	negative selection	10454904
57671470	57671493	18	-	28162770	SKM1	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	-0.4349785749127584	[51]	[67]	-4	hSpCas9	negative selection	10454905
57662571	57662594	18	-	28162770	SKM1	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	0.9951342448281841	[20]	[73]	8	hSpCas9	negative selection	10454906
57662505	57662528	18	+	28162770	SKM1	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	-0.2914869813232256	[35]	[51]	-2	hSpCas9	negative selection	10454907
57701246	57701269	18	+	28162770	SKM1	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.7357759733729201	[124]	[367]	7	hSpCas9	negative selection	10624264
57652566	57652589	18	-	28162770	SKM1	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	-0.3332545125601525	[61]	[86]	-3	hSpCas9	negative selection	10624265
57661334	57661357	18	-	28162770	SKM1	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	0.13219461236486985	[31]	[61]	1	hSpCas9	negative selection	10624266
57731697	57731720	18	-	28162770	SKM1	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	-0.5088438127623752	[98]	[122]	-4	hSpCas9	negative selection	10624267
57697628	57697651	18	+	28162770	SKM1	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	-0.167137184070693	[46]	[73]	-1	hSpCas9	negative selection	10624268
57685089	57685112	18	+	28162770	SKM1	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.34603619387604156	[84]	[190]	3	hSpCas9	negative selection	10624269
57684048	57684071	18	-	28162770	SKM1	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	0.7473639476481321	[30]	[91]	7	hSpCas9	negative selection	10624270
57671470	57671493	18	-	28162770	SKM1	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	-0.4349785749127584	[51]	[67]	-4	hSpCas9	negative selection	10624271
57662571	57662594	18	-	28162770	SKM1	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	0.9951342448281841	[20]	[73]	8	hSpCas9	negative selection	10624272
57662505	57662528	18	+	28162770	SKM1	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	-0.2914869813232256	[35]	[51]	-2	hSpCas9	negative selection	10624273
57701246	57701269	18	+	28162770	PL21	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.36387200051647706	[440]	[246]	3	hSpCas9	negative selection	10793630
57652566	57652589	18	-	28162770	PL21	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	-1.8612609301748229	[191]	[22]	-8	hSpCas9	negative selection	10793631
57661334	57661357	18	-	28162770	PL21	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	0.09207986863186712	[96]	[44]	0	hSpCas9	negative selection	10793632
57731697	57731720	18	-	28162770	PL21	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.5508680812295117	[366]	[233]	5	hSpCas9	negative selection	10793633
57697628	57697651	18	+	28162770	PL21	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.6637070076958227	[189]	[130]	6	hSpCas9	negative selection	10793634
57685089	57685112	18	+	28162770	PL21	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	-0.45794081543585125	[343]	[108]	-3	hSpCas9	negative selection	10793635
57684048	57684071	18	-	28162770	PL21	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	-0.451937082090373	[109]	[34]	-3	hSpCas9	negative selection	10793636
57671470	57671493	18	-	28162770	PL21	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	0.8548110870218808	[201]	[158]	7	hSpCas9	negative selection	10793637
57662571	57662594	18	-	28162770	PL21	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	-1.9697853869529922	[98]	[10]	-8	hSpCas9	negative selection	10793638
57662505	57662528	18	+	28162770	PL21	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	0.23184847421665833	[89]	[45]	2	hSpCas9	negative selection	10793639
57701246	57701269	18	+	28162770	P31FUJ	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.22691890856338803	[452]	[622]	2	hSpCas9	negative selection	10962996
57652566	57652589	18	-	28162770	P31FUJ	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	0.6464456361250112	[273]	[503]	7	hSpCas9	negative selection	10962997
57661334	57661357	18	-	28162770	P31FUJ	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	0.40679555288362346	[94]	[147]	4	hSpCas9	negative selection	10962998
57731697	57731720	18	-	28162770	P31FUJ	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.5197009588080203	[313]	[528]	6	hSpCas9	negative selection	10962999
57697628	57697651	18	+	28162770	P31FUJ	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.10778534570458409	[168]	[213]	1	hSpCas9	negative selection	10963000
57685089	57685112	18	+	28162770	P31FUJ	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.3886861723318915	[324]	[499]	4	hSpCas9	negative selection	10963001
57684048	57684071	18	-	28162770	P31FUJ	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	-0.31670346202332383	[176]	[166]	-3	hSpCas9	negative selection	10963002
57671470	57671493	18	-	28162770	P31FUJ	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	-0.1052141495295264	[291]	[318]	-1	hSpCas9	negative selection	10963003
57662571	57662594	18	-	28162770	P31FUJ	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	0.025265948526065785	[96]	[115]	0	hSpCas9	negative selection	10963004
57662505	57662528	18	+	28162770	P31FUJ	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	0.05591884508306483	[166]	[203]	0	hSpCas9	negative selection	10963005
57701246	57701269	18	+	28162770	OCIAML5	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.5746662620472215	[214]	[577]	5	hSpCas9	negative selection	11132362
57652566	57652589	18	-	28162770	OCIAML5	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	0.9400215945402968	[94]	[328]	7	hSpCas9	negative selection	11132363
57661334	57661357	18	-	28162770	OCIAML5	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	1.0523557691537717	[38]	[145]	8	hSpCas9	negative selection	11132364
57731697	57731720	18	-	28162770	OCIAML5	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.6528023386439122	[178]	[507]	6	hSpCas9	negative selection	11132365
57697628	57697651	18	+	28162770	OCIAML5	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.11201385488106028	[121]	[237]	0	hSpCas9	negative selection	11132366
57685089	57685112	18	+	28162770	OCIAML5	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	-0.26205084241655524	[189]	[285]	-2	hSpCas9	negative selection	11132367
57684048	57684071	18	-	28162770	OCIAML5	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	0.6889079174798218	[110]	[322]	6	hSpCas9	negative selection	11132368
57671470	57671493	18	-	28162770	OCIAML5	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	1.0692214531219624	[112]	[427]	8	hSpCas9	negative selection	11132369
57662571	57662594	18	-	28162770	OCIAML5	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	-0.3545669113931802	[67]	[95]	-3	hSpCas9	negative selection	11132370
57662505	57662528	18	+	28162770	OCIAML5	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	1.185408134554666	[37]	[155]	8	hSpCas9	negative selection	11132371
57701246	57701269	18	+	28162770	EOL1	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.5443916347617512	[789]	[606]	5	hSpCas9	negative selection	11301728
57652566	57652589	18	-	28162770	EOL1	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	0.6811421724856732	[218]	[184]	6	hSpCas9	negative selection	11301729
57661334	57661357	18	-	28162770	EOL1	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	-0.870133320451959	[169]	[48]	-6	hSpCas9	negative selection	11301730
57731697	57731720	18	-	28162770	EOL1	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.6898276473311546	[665]	[565]	6	hSpCas9	negative selection	11301731
57697628	57697651	18	+	28162770	EOL1	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.16795337065539562	[369]	[218]	1	hSpCas9	negative selection	11301732
57685089	57685112	18	+	28162770	EOL1	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.07747242048664438	[625]	[347]	0	hSpCas9	negative selection	11301733
57684048	57684071	18	-	28162770	EOL1	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	0.8609826427930684	[115]	[110]	7	hSpCas9	negative selection	11301734
57671470	57671493	18	-	28162770	EOL1	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	-0.007280725787886133	[247]	[129]	0	hSpCas9	negative selection	11301735
57662571	57662594	18	-	28162770	EOL1	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	0.6758686587138109	[119]	[100]	6	hSpCas9	negative selection	11301736
57662505	57662528	18	+	28162770	EOL1	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	-0.5527740059626518	[141]	[50]	-4	hSpCas9	negative selection	11301737
57701246	57701269	18	+	28162770	MOLM13	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.6925956687192731	[533]	[623]	5	hSpCas9	negative selection	11471094
57652566	57652589	18	-	28162770	MOLM13	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	0.40025066466921544	[261]	[249]	3	hSpCas9	negative selection	11471095
57661334	57661357	18	-	28162770	MOLM13	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	1.337828840980206	[115]	[211]	8	hSpCas9	negative selection	11471096
57731697	57731720	18	-	28162770	MOLM13	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.5350035774031157	[566]	[593]	4	hSpCas9	negative selection	11471097
57697628	57697651	18	+	28162770	MOLM13	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.016326006240621083	[319]	[233]	0	hSpCas9	negative selection	11471098
57685089	57685112	18	+	28162770	MOLM13	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.17099783759454046	[456]	[371]	1	hSpCas9	negative selection	11471099
57684048	57684071	18	-	28162770	MOLM13	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	-0.28575495376825766	[144]	[85]	-2	hSpCas9	negative selection	11471100
57671470	57671493	18	-	28162770	MOLM13	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	0.26748596398118885	[292]	[254]	2	hSpCas9	negative selection	11471101
57662571	57662594	18	-	28162770	MOLM13	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	0.33499511104723345	[124]	[113]	2	hSpCas9	negative selection	11471102
57662505	57662528	18	+	28162770	MOLM13	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	0.6783091612149508	[120]	[139]	5	hSpCas9	negative selection	11471103
57701246	57701269	18	+	28162770	HEL	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.4783520140994746	[519]	[463]	4	hSpCas9	negative selection	11640460
57652566	57652589	18	-	28162770	HEL	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	0.22770133272151322	[227]	[170]	1	hSpCas9	negative selection	11640461
57661334	57661357	18	-	28162770	HEL	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	0.9237589833075133	[92]	[112]	7	hSpCas9	negative selection	11640462
57731697	57731720	18	-	28162770	HEL	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.5148386029545089	[553]	[506]	4	hSpCas9	negative selection	11640463
57697628	57697651	18	+	28162770	HEL	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.6713079841971281	[249]	[254]	6	hSpCas9	negative selection	11640464
57685089	57685112	18	+	28162770	HEL	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.1038727458686548	[384]	[264]	0	hSpCas9	negative selection	11640465
57684048	57684071	18	-	28162770	HEL	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	0.6768870544122026	[166]	[170]	6	hSpCas9	negative selection	11640466
57671470	57671493	18	-	28162770	HEL	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	-0.38448263673466754	[213]	[104]	-3	hSpCas9	negative selection	11640467
57662571	57662594	18	-	28162770	HEL	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	-0.1646160900572472	[125]	[71]	-1	hSpCas9	negative selection	11640468
57662505	57662528	18	+	28162770	HEL	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	-0.08997728916449144	[112]	[67]	0	hSpCas9	negative selection	11640469
57701246	57701269	18	+	28162770	MV411	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.23079728509494735	[435]	[430]	2	hSpCas9	negative selection	11809826
57652566	57652589	18	-	28162770	MV411	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	0.44234923569711615	[158]	[181]	4	hSpCas9	negative selection	11809827
57661334	57661357	18	-	28162770	MV411	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	-0.03918367536863454	[110]	[90]	0	hSpCas9	negative selection	11809828
57731697	57731720	18	-	28162770	MV411	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.2909391894193619	[293]	[302]	2	hSpCas9	negative selection	11809829
57697628	57697651	18	+	28162770	MV411	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	-0.5402588455043604	[163]	[94]	-4	hSpCas9	negative selection	11809830
57685089	57685112	18	+	28162770	MV411	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	-0.704582420315403	[413]	[213]	-5	hSpCas9	negative selection	11809831
57684048	57684071	18	-	28162770	MV411	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	-0.4306343543298623	[119]	[74]	-3	hSpCas9	negative selection	11809832
57671470	57671493	18	-	28162770	MV411	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	0.6550955196960216	[195]	[259]	6	hSpCas9	negative selection	11809833
57662571	57662594	18	-	28162770	MV411	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	-0.44444015385489255	[41]	[25]	-3	hSpCas9	negative selection	11809834
57662505	57662528	18	+	28162770	MV411	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	0.41556030959110224	[88]	[99]	3	hSpCas9	negative selection	11809835
57701246	57701269	18	+	28162770	MONOMAC1	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.2005943756156745	[270]	[356]	2	hSpCas9	negative selection	11979192
57652566	57652589	18	-	28162770	MONOMAC1	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	1.6059878214993173	[142]	[498]	9	hSpCas9	negative selection	11979193
57661334	57661357	18	-	28162770	MONOMAC1	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	-1.035755940026493	[92]	[51]	-7	hSpCas9	negative selection	11979194
57731697	57731720	18	-	28162770	MONOMAC1	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.31438518864363263	[274]	[391]	3	hSpCas9	negative selection	11979195
57697628	57697651	18	+	28162770	MONOMAC1	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	1.4339953023575873	[112]	[349]	9	hSpCas9	negative selection	11979196
57685089	57685112	18	+	28162770	MONOMAC1	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.3666949756104776	[250]	[370]	3	hSpCas9	negative selection	11979197
57684048	57684071	18	-	28162770	MONOMAC1	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	0.5200291896689476	[72]	[119]	5	hSpCas9	negative selection	11979198
57671470	57671493	18	-	28162770	MONOMAC1	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	-0.42146841366960014	[117]	[100]	-4	hSpCas9	negative selection	11979199
57662571	57662594	18	-	28162770	MONOMAC1	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	0.9260215493447843	[72]	[158]	8	hSpCas9	negative selection	11979200
57662505	57662528	18	+	28162770	MONOMAC1	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	0.7276750256362091	[58]	[111]	7	hSpCas9	negative selection	11979201
57701246	57701269	18	+	28162770	OCIAML2	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.9556349294599367	[67]	[730]	8	hSpCas9	negative selection	12148558
57652566	57652589	18	-	28162770	OCIAML2	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	0.19839694026746935	[24]	[158]	2	hSpCas9	negative selection	12148559
57661334	57661357	18	-	28162770	OCIAML2	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	-0.6486281272201558	[27]	[98]	-5	hSpCas9	negative selection	12148560
57731697	57731720	18	-	28162770	OCIAML2	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.284989452255733	[72]	[492]	2	hSpCas9	negative selection	12148561
57697628	57697651	18	+	28162770	OCIAML2	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.8562645225385505	[28]	[290]	8	hSpCas9	negative selection	12148562
57685089	57685112	18	+	28162770	OCIAML2	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	0.6003620063292774	[56]	[478]	6	hSpCas9	negative selection	12148563
57684048	57684071	18	-	28162770	OCIAML2	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	0.17626042462219693	[18]	[118]	1	hSpCas9	negative selection	12148564
57671470	57671493	18	-	28162770	OCIAML2	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	0.6858746604378295	[35]	[320]	6	hSpCas9	negative selection	12148565
57662571	57662594	18	-	28162770	OCIAML2	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	-0.2689959640725106	[14]	[68]	-2	hSpCas9	negative selection	12148566
57662505	57662528	18	+	28162770	OCIAML2	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	-0.08730118569065548	[22]	[119]	0	hSpCas9	negative selection	12148567
57701246	57701269	18	+	28162770	OCIAML3	viability	ACGCCCAGCACCACAAGCAGGGG	ATP8B1	ENSG00000081923	0.9958042600583887	[98]	[595]	8	hSpCas9	negative selection	12317924
57652566	57652589	18	-	28162770	OCIAML3	viability	GGAGCTTATCTGCAAACCGTAGG	ATP8B1	ENSG00000081923	0.19026366862039967	[62]	[216]	1	hSpCas9	negative selection	12317925
57661334	57661357	18	-	28162770	OCIAML3	viability	TAGAAGCTAAGAAAGAGCAGCGG	ATP8B1	ENSG00000081923	0.856653768685402	[29]	[163]	7	hSpCas9	negative selection	12317926
57731697	57731720	18	-	28162770	OCIAML3	viability	AAGATGAACTTGATGACCAGGGG	ATP8B1	ENSG00000081923	0.3047703094970353	[106]	[398]	3	hSpCas9	negative selection	12317927
57697628	57697651	18	+	28162770	OCIAML3	viability	CTGCTGTTTCCACATAGCAGAGG	ATP8B1	ENSG00000081923	0.8181182635347775	[30]	[164]	7	hSpCas9	negative selection	12317928
57685089	57685112	18	+	28162770	OCIAML3	viability	TGTGTTGAGAGGCATCCCGATGG	ATP8B1	ENSG00000081923	-0.18122611498568736	[79]	[212]	-1	hSpCas9	negative selection	12317929
57684048	57684071	18	-	28162770	OCIAML3	viability	AGTTTGCCACACAGTCATGGTGG	ATP8B1	ENSG00000081923	-1.3424688733281989	[41]	[49]	-7	hSpCas9	negative selection	12317930
57671470	57671493	18	-	28162770	OCIAML3	viability	GCAAGAAACACAGGATGCCCTGG	ATP8B1	ENSG00000081923	0.41816707362193917	[58]	[237]	4	hSpCas9	negative selection	12317931
57662571	57662594	18	-	28162770	OCIAML3	viability	GAAAACCAGAGGAATAGAGGTGG	ATP8B1	ENSG00000081923	0.6023895724793401	[23]	[109]	5	hSpCas9	negative selection	12317932
57662505	57662528	18	+	28162770	OCIAML3	viability	AAGGCACGGTTTCCACCGGGTGG	ATP8B1	ENSG00000081923	0.6447792192629533	[24]	[117]	6	hSpCas9	negative selection	12317933