Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6790
• Symbol: AURKA
• Description: aurora kinase A

DataSource: http://genomecrispr.dkfz.de/#!/results/AURKA

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
56386392	56386415	20	+	26472758	Jiyoye	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	-2.388683901713901	[124]	[17]	-8	hSpCas9	negative selection	13072
56386490	56386513	20	+	26472758	Jiyoye	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-1.0017211141034645	[546]	[205]	-6	hSpCas9	negative selection	13073
56386253	56386276	20	+	26472758	Jiyoye	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-2.645292038388262	[223]	[26]	-9	hSpCas9	negative selection	13074
56383028	56383051	20	-	26472758	Jiyoye	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-4.499715214102645	[179]	[5]	-9	hSpCas9	negative selection	13075
56383117	56383140	20	+	26472758	Jiyoye	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-2.4122523728523055	[119]	[16]	-8	hSpCas9	negative selection	13076
56370602	56370625	20	+	26472758	Jiyoye	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-5.199482190314602	[535]	[10]	-9	hSpCas9	negative selection	13077
56386301	56386324	20	+	26472758	Jiyoye	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-2.4257146326588686	[113]	[15]	-8	hSpCas9	negative selection	13078
56383167	56383190	20	-	26472758	Jiyoye	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	-0.9009469138564585	[51]	[20]	-6	hSpCas9	negative selection	13079
56373512	56373535	20	+	26472758	Jiyoye	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-2.762749619936439	[71]	[7]	-9	hSpCas9	negative selection	13080
56386263	56386286	20	-	26472758	Jiyoye	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-4.073951308230742	[200]	[8]	-9	hSpCas9	negative selection	13081
56386392	56386415	20	+	26472758	KBM7	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	-1.4001925835150155	[153,157]	[56,1]	-7	hSpCas9	negative selection	204190
56386490	56386513	20	+	26472758	KBM7	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.5888519846503135	[1610,1852]	[614,487]	-5	hSpCas9	negative selection	204191
56386253	56386276	20	+	26472758	KBM7	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-2.245728398017338	[929,692]	[76,81]	-8	hSpCas9	negative selection	204192
56383028	56383051	20	-	26472758	KBM7	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-3.144132424993451	[511,278]	[10,28]	-9	hSpCas9	negative selection	204193
56383117	56383140	20	+	26472758	KBM7	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-1.253282248377956	[730,332]	[149,57]	-7	hSpCas9	negative selection	204194
56370602	56370625	20	+	26472758	KBM7	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-1.5402740034941111	[1510,1237]	[229,212]	-8	hSpCas9	negative selection	204195
56386301	56386324	20	+	26472758	KBM7	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-0.973800003765914	[440,599]	[142,112]	-6	hSpCas9	negative selection	204196
56383167	56383190	20	-	26472758	KBM7	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	-0.16449576907297403	[459,339]	[183,149]	-2	hSpCas9	negative selection	204197
56373512	56373535	20	+	26472758	KBM7	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-1.6800509108191346	[392,347]	[95,16]	-8	hSpCas9	negative selection	204198
56386263	56386286	20	-	26472758	KBM7	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-1.3908375872602772	[734,529]	[119,104]	-7	hSpCas9	negative selection	204199
56386392	56386415	20	+	26472758	Raji	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	0.5739513352925256	[54]	[18]	5	hSpCas9	negative selection	395308
56386490	56386513	20	+	26472758	Raji	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.6265092247429835	[937]	[140]	-5	hSpCas9	negative selection	395309
56386253	56386276	20	+	26472758	Raji	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-1.9349272694843647	[345]	[20]	-8	hSpCas9	negative selection	395310
56383028	56383051	20	-	26472758	Raji	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-2.8926164646264008	[159]	[4]	-9	hSpCas9	negative selection	395311
56383117	56383140	20	+	26472758	Raji	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-1.905440504983984	[338]	[20]	-8	hSpCas9	negative selection	395312
56370602	56370625	20	+	26472758	Raji	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-3.458670502797492	[757]	[15]	-9	hSpCas9	negative selection	395313
56386301	56386324	20	+	26472758	Raji	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-0.3726094057460141	[105]	[18]	-3	hSpCas9	negative selection	395314
56383167	56383190	20	-	26472758	Raji	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	-0.3880273803692643	[202]	[35]	-3	hSpCas9	negative selection	395315
56373512	56373535	20	+	26472758	Raji	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-4.835130969965641	[122]	[0]	-9	hSpCas9	negative selection	395316
56386263	56386286	20	-	26472758	Raji	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-1.364291679018445	[354]	[31]	-7	hSpCas9	negative selection	395317
56386392	56386415	20	+	26472758	K562	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	1.116868677945936	[64]	[118]	8	hSpCas9	negative selection	586426
56386490	56386513	20	+	26472758	K562	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.6168400782974257	[1376]	[757]	-4	hSpCas9	negative selection	586427
56386253	56386276	20	+	26472758	K562	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-2.2858266033456407	[594]	[102]	-8	hSpCas9	negative selection	586428
56383028	56383051	20	-	26472758	K562	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-6.766808527756807	[386]	[2]	-9	hSpCas9	negative selection	586429
56383117	56383140	20	+	26472758	K562	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-2.3534828287622074	[447]	[73]	-8	hSpCas9	negative selection	586430
56370602	56370625	20	+	26472758	K562	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-4.038430047978982	[1128]	[57]	-9	hSpCas9	negative selection	586431
56386301	56386324	20	+	26472758	K562	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-1.7834872689034378	[260]	[63]	-7	hSpCas9	negative selection	586432
56383167	56383190	20	-	26472758	K562	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	-0.7866081679541778	[281]	[137]	-5	hSpCas9	negative selection	586433
56373512	56373535	20	+	26472758	K562	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-3.226372753135398	[254]	[22]	-8	hSpCas9	negative selection	586434
56386263	56386286	20	-	26472758	K562	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-1.359207617319745	[388]	[127]	-6	hSpCas9	negative selection	586435
56370465	56370488	20	-	26627737	DLD1	viability	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.5526213565827385	[576]	[191,223,360]	5	hSpCas9	negative selection	815201
56386247	56386270	20	+	26627737	DLD1	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	0.04411534070389678	[51]	[49,0,0]	0	hSpCas9	negative selection	815202
56386252	56386275	20	+	26627737	DLD1	viability	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	-0.6645446068137297	[372]	[34,52,123]	-6	hSpCas9	negative selection	815203
56370465	56370488	20	-	26627737	GBM cells	viability after 5 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.05510476529416919	[515]	[262,311]	0	hSpCas9	negative selection	897516
56386247	56386270	20	+	26627737	GBM cells	viability after 5 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.8015258432554067	[12]	[0,6]	-8	hSpCas9	negative selection	897517
56386252	56386275	20	+	26627737	GBM cells	viability after 5 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.6245936615053769	[230]	[166,214]	8	hSpCas9	negative selection	897518
56370465	56370488	20	-	26627737	GBM cells	viability after 13 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.3624342662832738	[515]	[349,367]	4	hSpCas9	negative selection	979831
56386247	56386270	20	+	26627737	GBM cells	viability after 13 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.3822374797559709	[12]	[0,8]	-4	hSpCas9	negative selection	979832
56386252	56386275	20	+	26627737	GBM cells	viability after 13 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.25719124280958444	[230]	[226,86]	3	hSpCas9	negative selection	979833
56370465	56370488	20	-	26627737	GBM cells	viability after 21 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.7051265504766138	[515]	[479,435]	7	hSpCas9	negative selection	1062146
56386247	56386270	20	+	26627737	GBM cells	viability after 21 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.4603104734390513	[12]	[0,3]	-8	hSpCas9	negative selection	1062147
56386252	56386275	20	+	26627737	GBM cells	viability after 21 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	-0.4507442992650143	[230]	[95,87]	-4	hSpCas9	negative selection	1062148
56370465	56370488	20	-	26627737	RPE1	viability after 9 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	1.145178278063015	[1318]	[849,994]	7	hSpCas9	negative selection	1144461
56386247	56386270	20	+	26627737	RPE1	viability after 9 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.9409887189842396	[108]	[14,0]	-8	hSpCas9	negative selection	1144462
56386252	56386275	20	+	26627737	RPE1	viability after 9 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	1.2742650016601365	[143]	[98,121]	7	hSpCas9	negative selection	1144463
56370465	56370488	20	-	26627737	RPE1	viability after 12 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	1.0893032756902574	[1318]	[634,879]	6	hSpCas9	negative selection	1226776
56386247	56386270	20	+	26627737	RPE1	viability after 12 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.0795149929742651	[108]	[25,0]	-6	hSpCas9	negative selection	1226777
56386252	56386275	20	+	26627737	RPE1	viability after 12 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.41068458450289613	[143]	[48,53]	2	hSpCas9	negative selection	1226778
56370465	56370488	20	-	26627737	RPE1	viability after 15 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.8851123075061507	[1318]	[710,667]	5	hSpCas9	negative selection	1309091
56386247	56386270	20	+	26627737	RPE1	viability after 15 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-4.946435450905032	[108]	[0,0]	-9	hSpCas9	negative selection	1309092
56386252	56386275	20	+	26627737	RPE1	viability after 15 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.14483704122372476	[143]	[42,46]	1	hSpCas9	negative selection	1309093
56370465	56370488	20	-	26627737	RPE1	viability after 18 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.7539644615121939	[1318]	[637,559]	4	hSpCas9	negative selection	1391406
56386247	56386270	20	+	26627737	RPE1	viability after 18 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-4.878516064676184	[108]	[0,0]	-9	hSpCas9	negative selection	1391407
56386252	56386275	20	+	26627737	RPE1	viability after 18 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.3163393157164087	[143]	[15,82]	2	hSpCas9	negative selection	1391408
56370465	56370488	20	-	26627737	HeLa	viability after 8 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.14952928963439716	[847]	[416,468,347]	1	hSpCas9	negative selection	1473721
56386247	56386270	20	+	26627737	HeLa	viability after 8 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-2.5788048067582254	[85]	[0,0,14]	-9	hSpCas9	negative selection	1473722
56386252	56386275	20	+	26627737	HeLa	viability after 8 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.2567063878892377	[427]	[306,228,154]	2	hSpCas9	negative selection	1473723
56370465	56370488	20	-	26627737	HeLa	viability after 12 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	-0.022917813934295372	[847]	[342,313,380]	0	hSpCas9	negative selection	1556036
56386247	56386270	20	+	26627737	HeLa	viability after 12 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.4129871198509334	[85]	[4,1,33]	-8	hSpCas9	negative selection	1556037
56386252	56386275	20	+	26627737	HeLa	viability after 12 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.15475906301700712	[427]	[179,132,283]	1	hSpCas9	negative selection	1556038
56370465	56370488	20	-	26627737	HeLa	viability after 15 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.16312213689458988	[847]	[459,380,311]	1	hSpCas9	negative selection	1638351
56386247	56386270	20	+	26627737	HeLa	viability after 15 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.6866649200998305	[85]	[0,29,0]	-9	hSpCas9	negative selection	1638352
56386252	56386275	20	+	26627737	HeLa	viability after 15 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.20587661143826455	[427]	[165,143,300]	1	hSpCas9	negative selection	1638353
56370465	56370488	20	-	26627737	HeLa	viability after 18 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.17795930206915722	[847]	[315,315,311]	1	hSpCas9	negative selection	1720666
56386247	56386270	20	+	26627737	HeLa	viability after 18 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.6558701791343222	[85]	[0,24,0]	-8	hSpCas9	negative selection	1720667
56386252	56386275	20	+	26627737	HeLa	viability after 18 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.1678494071684495	[427]	[98,121,300]	1	hSpCas9	negative selection	1720668
56370465	56370488	20	-	26627737	HCT116	viability after 6 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.2751278699741584	[1128]	[489,62]	1	hSpCas9	negative selection	1802981
56386247	56386270	20	+	26627737	HCT116	viability after 6 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.0683678989790248	[202]	[40,0]	-6	hSpCas9	negative selection	1802982
56386252	56386275	20	+	26627737	HCT116	viability after 6 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	-0.7860724138744646	[587]	[148,0]	-4	hSpCas9	negative selection	1802983
56370465	56370488	20	-	26627737	HCT116	viability after 8 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.46670110875527004	[531]	[321,498,392]	5	hSpCas9	negative selection	1885296
56386247	56386270	20	+	26627737	HCT116	viability after 8 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.68730257546504	[55]	[17,9,0]	-9	hSpCas9	negative selection	1885297
56386252	56386275	20	+	26627737	HCT116	viability after 8 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.3419016571555758	[191]	[143,169,88]	3	hSpCas9	negative selection	1885298
56370465	56370488	20	-	26627737	HCT116	viability after 9 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.050145351646515124	[1128]	[391,248]	0	hSpCas9	negative selection	1967611
56386247	56386270	20	+	26627737	HCT116	viability after 9 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-2.4940660404942596	[202]	[17,2]	-9	hSpCas9	negative selection	1967612
56386252	56386275	20	+	26627737	HCT116	viability after 9 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.42764809658699887	[587]	[342,106]	3	hSpCas9	negative selection	1967613
56370465	56370488	20	-	26627737	HCT116	viability after 12 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.0010307795327819669	[531]	[323,260,249]	0	hSpCas9	negative selection	2049926
56386247	56386270	20	+	26627737	HCT116	viability after 12 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.4413745647354852	[55]	[4,42,18]	-5	hSpCas9	negative selection	2049927
56386252	56386275	20	+	26627737	HCT116	viability after 12 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.579227947630201	[191]	[118,148,186]	5	hSpCas9	negative selection	2049928
56370465	56370488	20	-	26627737	HCT116	viability after 15 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.254400144320415	[531]	[400,267,427]	2	hSpCas9	negative selection	2132241
56386247	56386270	20	+	26627737	HCT116	viability after 15 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.246824484775472	[55]	[0,13,23]	-8	hSpCas9	negative selection	2132242
56386252	56386275	20	+	26627737	HCT116	viability after 15 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.24195838388044377	[191]	[151,125,115]	2	hSpCas9	negative selection	2132243
56370465	56370488	20	-	26627737	HCT116	viability after 18 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.6789194803309363	[531]	[428,406,398]	5	hSpCas9	negative selection	2214556
56386247	56386270	20	+	26627737	HCT116	viability after 18 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.7770015344735679	[55]	[1,41,0]	-6	hSpCas9	negative selection	2214557
56386252	56386275	20	+	26627737	HCT116	viability after 18 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.9711321637944172	[191]	[162,128,260]	7	hSpCas9	negative selection	2214558
56386365	56386388	20	-	24336569	HL60	viability	GCTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	0.05425390922866424	[734]	[1614]	0	hSpCas9	negative selection	2249254
56386392	56386415	20	+	24336569	HL60	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	0.13870681768861748	[1206]	[2811]	1	hSpCas9	negative selection	2249255
56386406	56386429	20	+	24336569	HL60	viability	ATGCGCTGGGAAGAATTTGAAGG	AURKA	ENSG00000087586	0.6358829532171812	[384]	[1265]	5	hSpCas9	negative selection	2249256
56386428	56386451	20	+	24336569	HL60	viability	GACACAAGACCCGCTGAGCCTGG	AURKA	ENSG00000087586	0.16148353988970476	[1114]	[2638]	1	hSpCas9	negative selection	2249257
56386437	56386460	20	-	24336569	HL60	viability	AAATAGTGGCCAGGCTCAGCGGG	AURKA	ENSG00000087586	0.3994102879637087	[1450]	[4049]	3	hSpCas9	negative selection	2249258
56386442	56386465	20	+	24336569	HL60	viability	TGAGCCTGGCCACTATTTACAGG	AURKA	ENSG00000087586	1.1296130074797177	[191]	[888]	8	hSpCas9	negative selection	2249259
56386448	56386471	20	+	24336569	HL60	viability	TGGCCACTATTTACAGGTAATGG	AURKA	ENSG00000087586	0.5836687487762431	[314]	[998]	5	hSpCas9	negative selection	2249260
56386514	56386537	20	-	24336569	HL60	viability	TAGGCTACAGCTCCAGTTGGAGG	AURKA	ENSG00000087586	-1.1629335894645034	[1110]	[1049]	-8	hSpCas9	negative selection	2249261
56388142	56388165	20	+	24336569	HL60	viability	ATTATTCAATTTACCTTAACAGG	AURKA	ENSG00000087586	0.67366516023491	[220]	[745]	6	hSpCas9	negative selection	2249262
56388155	56388178	20	-	24336569	HL60	viability	CTGCATTTCAGGACCTGTTAAGG	AURKA	ENSG00000087586	0.3639470476934663	[328]	[895]	3	hSpCas9	negative selection	2249263
56386365	56386388	20	-	24336569	KBM7	viability	GCTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	1.4299067604908466	[151]	[1116]	9	hSpCas9	negative selection	2316431
56386392	56386415	20	+	24336569	KBM7	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	-1.512767616187561	[1425]	[1362]	-7	hSpCas9	negative selection	2316432
56386406	56386429	20	+	24336569	KBM7	viability	ATGCGCTGGGAAGAATTTGAAGG	AURKA	ENSG00000087586	0.26862783745052626	[363]	[1195]	2	hSpCas9	negative selection	2316433
56386428	56386451	20	+	24336569	KBM7	viability	GACACAAGACCCGCTGAGCCTGG	AURKA	ENSG00000087586	-0.6870645286942508	[1032]	[1749]	-5	hSpCas9	negative selection	2316434
56386437	56386460	20	-	24336569	KBM7	viability	AAATAGTGGCCAGGCTCAGCGGG	AURKA	ENSG00000087586	-0.7386125907079234	[1102]	[1802]	-5	hSpCas9	negative selection	2316435
56386442	56386465	20	+	24336569	KBM7	viability	TGAGCCTGGCCACTATTTACAGG	AURKA	ENSG00000087586	1.5756531096888344	[153]	[1251]	9	hSpCas9	negative selection	2316436
56386448	56386471	20	+	24336569	KBM7	viability	TGGCCACTATTTACAGGTAATGG	AURKA	ENSG00000087586	1.1868519804365736	[257]	[1601]	8	hSpCas9	negative selection	2316437
56386514	56386537	20	-	24336569	KBM7	viability	TAGGCTACAGCTCCAGTTGGAGG	AURKA	ENSG00000087586	-0.8516788493428382	[437]	[661]	-6	hSpCas9	negative selection	2316438
56388142	56388165	20	+	24336569	KBM7	viability	ATTATTCAATTTACCTTAACAGG	AURKA	ENSG00000087586	0.4610718569240734	[272]	[1024]	4	hSpCas9	negative selection	2316439
56388155	56388178	20	-	24336569	KBM7	viability	CTGCATTTCAGGACCTGTTAAGG	AURKA	ENSG00000087586	0.2544679814140956	[275]	[897]	2	hSpCas9	negative selection	2316440
56392204	56392227	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAAGAACCTTTGAATTCTAACGG	AURKA	ENSG00000087586	0.7255720702809914	[41,104]	[8,44]	3	dCas9-VP64	positive selection	2390880
56392183	56392206	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCTGAGCTCTTGGAAGACTTGG	AURKA	ENSG00000087586	-0.06841594515366944	[14,1]	[1,0]	0	dCas9-VP64	positive selection	2390882
56392262	56392285	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCGCTCGAGCGCAGGCCAATCGG	AURKA	ENSG00000087586	0.9191703249123369	[81,317]	[8,164]	4	dCas9-VP64	positive selection	2390883
56392334	56392357	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	TAAGGGCGCACACCGCGCGCAGG	AURKA	ENSG00000087586	-0.14385052041469093	[14,18]	[3,1]	0	dCas9-VP64	positive selection	2427771
56392204	56392227	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAAGAACCTTTGAATTCTAACGG	AURKA	ENSG00000087586	-0.28747981568922876	[125,193]	[23,59]	-3	dCas9-VP64	positive selection	2486135
56392183	56392206	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCTGAGCTCTTGGAAGACTTGG	AURKA	ENSG00000087586	1.597868851433834	[56,59]	[102,15]	8	dCas9-VP64	positive selection	2486137
56392262	56392285	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCGCTCGAGCGCAGGCCAATCGG	AURKA	ENSG00000087586	0.2702117659774377	[71,74]	[26,29]	2	dCas9-VP64	positive selection	2486138
56392334	56392357	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	TAAGGGCGCACACCGCGCGCAGG	AURKA	ENSG00000087586	1.3849888554015446	[58,12]	[60,3]	7	dCas9-VP64	positive selection	2523026
56388155	56388178	20	-	27013184	SW480	treatment with recombinant TRAIL	CTGCATTTCAGGACCTGTTAAGG	AURKA	ENSG00000087586	-1.5445733044560588	[136,137]	[2,44]	-6	hSpCas9	positive selection	2955704
56386238	56386261	20	+	27013184	SW480	treatment with recombinant TRAIL	GTCTCAAAAGCTAGTTTACCAGG	AURKA	ENSG00000087586	-4.60202303436882	[260,442]	[8,1]	-9	hSpCas9	positive selection	2955705
56386247	56386270	20	+	27013184	SW480	treatment with recombinant TRAIL	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.8161253439710618	[142,55]	[7,49]	-4	hSpCas9	positive selection	2955706
56386251	56386274	20	+	27013184	SW480	treatment with recombinant TRAIL	GTTTACCAGGTGCCGATGGCAGG	AURKA	ENSG00000087586	-0.34765689142184586	[177,248]	[105,21]	-1	hSpCas9	positive selection	2955707
56386252	56386275	20	+	27013184	SW480	treatment with recombinant TRAIL	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	-0.2653397772100008	[564,460]	[125,270]	-1	hSpCas9	positive selection	2955708
56386253	56386276	20	+	27013184	SW480	treatment with recombinant TRAIL	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-0.4449329062446	[143,144]	[6,100]	-2	hSpCas9	positive selection	2955709
56386309	56386332	20	+	27013184	SW480	treatment with recombinant TRAIL	GGAGACAGGATGAGGTACACTGG	AURKA	ENSG00000087586	-4.604066626966873	[312,485]	[1,13]	-9	hSpCas9	positive selection	2955710
56386346	56386369	20	+	27013184	SW480	treatment with recombinant TRAIL	TTCTGCTTCTGATTCTGAACCGG	AURKA	ENSG00000087586	-4.485961912082388	[116,335]	[4,2]	-9	hSpCas9	positive selection	2955711
56386357	56386380	20	+	27013184	SW480	treatment with recombinant TRAIL	ATTCTGAACCGGCTTGTGACTGG	AURKA	ENSG00000087586	0.4499014692112884	[24,78]	[1,67]	2	hSpCas9	positive selection	2955713
56386382	56386405	20	+	27013184	SW480	treatment with recombinant TRAIL	ACAAGCTTTTGTGCTTGCAAAGG	AURKA	ENSG00000087586	-0.8933338257372128	[183,144]	[50,20]	-4	hSpCas9	positive selection	2955715
56386392	56386415	20	+	27013184	SW480	treatment with recombinant TRAIL	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	1.2096217156717701	[52,39]	[1,110]	5	hSpCas9	positive selection	2955716
56386393	56386416	20	+	27013184	SW480	treatment with recombinant TRAIL	TGCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	2.1055945277270287	[167,263]	[287,542]	8	hSpCas9	positive selection	2955717
56386442	56386465	20	+	27013184	SW480	treatment with recombinant TRAIL	TGAGCCTGGCCACTATTTACAGG	AURKA	ENSG00000087586	-0.6271634322746654	[422,755]	[63,297]	-3	hSpCas9	positive selection	2955718
56386448	56386471	20	+	27013184	SW480	treatment with recombinant TRAIL	TGGCCACTATTTACAGGTAATGG	AURKA	ENSG00000087586	1.557214186966702	[192,314]	[377,226]	7	hSpCas9	positive selection	2955719
56386460	56386483	20	+	27013184	SW480	treatment with recombinant TRAIL	ACAGGTAATGGATTCTGACAAGG	AURKA	ENSG00000087586	-1.108655360677529	[73,100]	[1,38]	-5	hSpCas9	positive selection	2955721
56386490	56386513	20	+	27013184	SW480	treatment with recombinant TRAIL	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	0.711236196980626	[314,262]	[315,48]	3	hSpCas9	positive selection	2955722
56386502	56386525	20	+	27013184	SW480	treatment with recombinant TRAIL	ACACGTTTTGGACCTCCAACTGG	AURKA	ENSG00000087586	1.3788873988199921	[668,959]	[1185,491]	6	hSpCas9	positive selection	2955723
56386520	56386543	20	+	27013184	SW480	treatment with recombinant TRAIL	ACTGGAGCTGTAGCCTAGAATGG	AURKA	ENSG00000087586	-4.709091526184826	[461,317]	[1,12]	-9	hSpCas9	positive selection	2955724
56383173	56383196	20	-	27013184	SW480	treatment with recombinant TRAIL	GTGTTCAAATTCCTCCTAGGAGG	AURKA	ENSG00000087586	-0.543218874700456	[47,48]	[15,11]	-2	hSpCas9	positive selection	2955725
56384301	56384324	20	-	27013184	SW480	treatment with recombinant TRAIL	AAATAATCCTGAGGAGGAACTGG	AURKA	ENSG00000087586	-3.7450229754172843	[89,56]	[1,2]	-9	hSpCas9	positive selection	2955727
56384310	56384333	20	-	27013184	SW480	treatment with recombinant TRAIL	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-3.614252856437463	[43,71]	[1,1]	-9	hSpCas9	positive selection	2955728
56386256	56386279	20	-	27013184	SW480	treatment with recombinant TRAIL	CAGCCCCTGCCATCGGCACCTGG	AURKA	ENSG00000087586	1.7999634351680944	[353,302]	[489,506]	7	hSpCas9	positive selection	2955729
56386365	56386388	20	-	27013184	SW480	treatment with recombinant TRAIL	GCTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	0.022112512427112763	[339,486]	[108,276]	0	hSpCas9	positive selection	2955731
56386437	56386460	20	-	27013184	SW480	treatment with recombinant TRAIL	AAATAGTGGCCAGGCTCAGCGGG	AURKA	ENSG00000087586	0.8660748672261076	[206,254]	[120,263]	4	hSpCas9	positive selection	2955732
56386446	56386469	20	-	27013184	SW480	treatment with recombinant TRAIL	ATTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	1.8575609366090764	[638,720]	[1183,877]	8	hSpCas9	positive selection	2955733
56386451	56386474	20	-	27013184	SW480	treatment with recombinant TRAIL	AATCCATTACCTGTAAATAGTGG	AURKA	ENSG00000087586	-2.371904371308231	[15,48]	[2,1]	-8	hSpCas9	positive selection	2955734
56386514	56386537	20	-	27013184	SW480	treatment with recombinant TRAIL	TAGGCTACAGCTCCAGTTGGAGG	AURKA	ENSG00000087586	3.1221336655199146	[418,501]	[1717,1713]	9	hSpCas9	positive selection	2955735
56386517	56386540	20	-	27013184	SW480	treatment with recombinant TRAIL	TTCTAGGCTACAGCTCCAGTTGG	AURKA	ENSG00000087586	-2.862404446476986	[787,874]	[25,81]	-8	hSpCas9	positive selection	2955736
56384294	56384317	20	+	27013184	SW480	treatment with recombinant TRAIL	TTTGATGCCAGTTCCTCCTCAGG	AURKA	ENSG00000087586	-2.37457954898668	[253,285]	[23,19]	-8	hSpCas9	positive selection	2955738
56384310	56384333	20	+	27013184	SW480	treatment with recombinant TRAIL	CCTCAGGATTATTTTCTATATGG	AURKA	ENSG00000087586	0.22253308367767466	[396,396]	[144,277]	1	hSpCas9	positive selection	2955739
56383118	56383141	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-0.43970481028813985	[2,2]	[2,0]	-6	hSpCas9	positive selection	2972657
56386248	56386271	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	0.1765348272325406	[3,3]	[2,3]	4	hSpCas9	positive selection	2972658
56386365	56386388	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-0.1613018361643783	[4,4]	[3,3]	-2	hSpCas9	positive selection	2972659
56386254	56386277	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-0.25453696464378267	[2,2]	[1,1]	-4	hSpCas9	positive selection	2972660
56383118	56383141	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	0.5902037795742241	[2,2]	[1,2]	8	hSpCas9	positive selection	3040515
56386248	56386271	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.39723844879161124	[3,3]	[3,0]	-6	hSpCas9	positive selection	3040516
56386365	56386388	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	0.22879138016768746	[4,4]	[4,3]	4	hSpCas9	positive selection	3040517
56386254	56386277	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-0.9931591956988334	[2,2]	[1,0]	-9	hSpCas9	positive selection	3040518
56384310	56384333		-	24336571	A375	resistance to PLX after 7 days	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	0.14251017787005793	[1,2]	[2,2]	4	hSpCas9	positive selection	3140071
56386263	56386286		-	24336571	A375	resistance to PLX after 7 days	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-0.4212239891648305	[6,5]	[4,4]	-9	hSpCas9	positive selection	3140082
56386247	56386270		+	24336571	A375	resistance to PLX after 7 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	0.12217303812994884	[2,3]	[3,3]	4	hSpCas9	positive selection	3140093
56384310	56384333		-	24336571	A375	resistance to PLX after 14 days	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	0.8746687291250017	[1,1]	[1,1]	7	hSpCas9	positive selection	3197864
56386263	56386286		-	24336571	A375	resistance to PLX after 14 days	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-0.3186169768827396	[3,6]	[1,1]	-4	hSpCas9	positive selection	3197875
56386247	56386270		+	24336571	A375	resistance to PLX after 14 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.2797668473874253	[2,6]	[1,1]	-3	hSpCas9	positive selection	3197886
56384310	56384333		-	24336571	A375	viability after 7 days	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.8681872713679837	[10]	[1,2]	-9	hSpCas9	negative selection	3255657
56386263	56386286		-	24336571	A375	viability after 7 days	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-0.3636385704375851	[8]	[6,5]	-5	hSpCas9	negative selection	3255668
56386247	56386270		+	24336571	A375	viability after 7 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.6787528636127935	[5]	[2,3]	-7	hSpCas9	negative selection	3255679
56384310	56384333		-	24336571	A375	viability after 14 days	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.9913291672894238	[10]	[1,1]	-9	hSpCas9	negative selection	3313450
56386263	56386286		-	24336571	A375	viability after 14 days	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-0.5675907635962575	[8]	[3,6]	-6	hSpCas9	negative selection	3313461
56386247	56386270		+	24336571	A375	viability after 14 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.14150041279989134	[5]	[2,6]	-2	hSpCas9	negative selection	3313472
56386490	56386513	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	0.7053478463224093	[67,119]	[0,0]	3	hSpCas9	positive selection	3338294
56386247	56386270	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	2.9316312866355534	[27,11]	[0,0]	8	hSpCas9	positive selection	3338295
56383014	56383037	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	3.353582171154181	[9,19]	[0,0]	9	hSpCas9	positive selection	3338296
56383133	56383156	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.06460188344152731	[159,159]	[0,0]	0	hSpCas9	positive selection	3357554
56384310	56384333	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	1.2800462879459185	[62,62]	[0,0]	5	hSpCas9	positive selection	3357555
56384294	56384317	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTTGATGCCAGTTCCTCCTCAGG	AURKA	ENSG00000087586	-0.7084580732162519	[249,249]	[0,0]	-5	hSpCas9	positive selection	3357556
56383117	56383140	20	+	26780180	HT29	viability (Avana library 4 designs)	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	4.67486966432917	[]	[]	9	hSpCas9	negative selection	3408812
56386247	56386270	20	+	26780180	HT29	viability (Avana library 4 designs)	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	2.41089185365385	[]	[]	8	hSpCas9	negative selection	3408813
56386365	56386388	20	-	26780180	HT29	viability (Avana library 4 designs)	GCTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	0.491379663729161	[]	[]	1	hSpCas9	negative selection	3408814
56386253	56386276	20	+	26780180	HT29	viability (Avana library 4 designs)	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	3.11217647714591	[]	[]	8	hSpCas9	negative selection	3408815
56386365	56386388	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-8.79386971461017	[]	[]	-7	hSpCas9	negative selection	3482532
56386253	56386276	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-7.77198805743886	[]	[]	-7	hSpCas9	negative selection	3482533
56386247	56386270	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-2.38346237602978	[]	[]	-3	hSpCas9	negative selection	3482534
56383117	56383140	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-15.0222401271084	[]	[]	-9	hSpCas9	negative selection	3482535
56383144	56383167	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTTGGAAGACTTTGAAATTGG	AURKA	ENSG00000087586	-0.40144676625241	[]	[]	0	hSpCas9	negative selection	3482536
56386517	56386540	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCTAGGCTACAGCTCCAGTTGG	AURKA	ENSG00000087586	-3.65487009621048	[]	[]	-4	hSpCas9	negative selection	3482537
56386365	56386388	20	-	26780180	A375	viability (Avana lentiGuide)	GCTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	3.03961517417598	[]	[]	3	hSpCas9	negative selection	3591191
56386253	56386276	20	+	26780180	A375	viability (Avana lentiGuide)	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	29.618238697629	[]	[]	9	hSpCas9	negative selection	3591192
56386247	56386270	20	+	26780180	A375	viability (Avana lentiGuide)	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	12.6498316232056	[]	[]	7	hSpCas9	negative selection	3591193
56383117	56383140	20	+	26780180	A375	viability (Avana lentiGuide)	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	27.4775008623946	[]	[]	9	hSpCas9	negative selection	3591194
56383144	56383167	20	-	26780180	A375	viability (Avana lentiGuide)	GCTTTGGAAGACTTTGAAATTGG	AURKA	ENSG00000087586	1.33024751375824	[]	[]	1	hSpCas9	negative selection	3591195
56386517	56386540	20	-	26780180	A375	viability (Avana lentiGuide)	TTCTAGGCTACAGCTCCAGTTGG	AURKA	ENSG00000087586	13.687911689422	[]	[]	7	hSpCas9	negative selection	3591196
56386365	56386388	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-0.5699587218896831	[5]	[3,3]	-7	hSpCas9	positive selection	3699850
56386253	56386276	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-0.5573845357827764	[4]	[3,2]	-7	hSpCas9	positive selection	3699851
56386247	56386270	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.44079523993076825	[5]	[3,3]	-6	hSpCas9	positive selection	3699852
56383117	56383140	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-1.1375460964690978	[4]	[0,1]	-9	hSpCas9	positive selection	3699853
56383144	56383167	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTTGGAAGACTTTGAAATTGG	AURKA	ENSG00000087586	0.12682756202019735	[6]	[7,6]	3	hSpCas9	positive selection	3699854
56386517	56386540	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCTAGGCTACAGCTCCAGTTGG	AURKA	ENSG00000087586	-0.4079335271917275	[6]	[3,4]	-6	hSpCas9	positive selection	3699855
56386365	56386388	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	0.09485307766870588	[6]	[6,5]	2	hSpCas9	positive selection	3808457
56386253	56386276	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-1.8634573051321852	[5]	[0,0]	-9	hSpCas9	positive selection	3808458
56386247	56386270	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.8791613169511064	[6]	[0,3]	-8	hSpCas9	positive selection	3808459
56383117	56383140	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-1.3531650738239167	[5]	[1,0]	-9	hSpCas9	positive selection	3808460
56383144	56383167	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTTGGAAGACTTTGAAATTGG	AURKA	ENSG00000087586	0.2917116402293038	[7]	[7,7]	7	hSpCas9	positive selection	3808461
56386517	56386540	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCTAGGCTACAGCTCCAGTTGG	AURKA	ENSG00000087586	-0.05012463650356147	[7]	[5,5]	0	hSpCas9	positive selection	3808462
56384310	56384333	20	-	26780180	A375	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	1.59487550562559	[]	[]	8	hSpCas9	negative selection	3916714
56383133	56383156	20	-	26780180	A375	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	1.47229558000718	[]	[]	8	hSpCas9	negative selection	3916715
56386247	56386270	20	+	26780180	A375	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	1.47069203347833	[]	[]	8	hSpCas9	negative selection	3916716
56383014	56383037	20	+	26780180	A375	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	1.67740026591705	[]	[]	9	hSpCas9	negative selection	3916717
56386490	56386513	20	+	26780180	A375	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	1.58871184366099	[]	[]	8	hSpCas9	negative selection	3916718
56384310	56384333	20	-	26780180	HT29	viability (GeCKOv2 library)	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	1.79843482051499	[]	[]	8	hSpCas9	negative selection	4024680
56383133	56383156	20	-	26780180	HT29	viability (GeCKOv2 library)	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	0.808047467276457	[]	[]	3	hSpCas9	negative selection	4024681
56386247	56386270	20	+	26780180	HT29	viability (GeCKOv2 library)	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	1.59108963442148	[]	[]	8	hSpCas9	negative selection	4024682
56383014	56383037	20	+	26780180	HT29	viability (GeCKOv2 library)	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	2.33305414421707	[]	[]	9	hSpCas9	negative selection	4024683
56386490	56386513	20	+	26780180	HT29	viability (GeCKOv2 library)	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	1.33786465409813	[]	[]	6	hSpCas9	negative selection	4024684
56384310	56384333	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.18987385552689362	[1]	[1,0]	-4	hSpCas9	positive selection	4165466
56386263	56386286	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-0.5168945877537392	[3]	[1,0]	-8	hSpCas9	positive selection	4165477
56386247	56386270	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.8398460591558168	[2]	[0,0]	-9	hSpCas9	positive selection	4165488
56384310	56384333	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.18812945338846276	[1]	[0,0,0,0]	-3	hSpCas9	positive selection	4229488
56386263	56386286	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-0.29660011943460735	[2]	[0,0,0,0]	-4	hSpCas9	positive selection	4229499
56386247	56386270	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	1.1243294272389597	[0]	[0,3,0,0]	8	hSpCas9	positive selection	4229510
56386490	56386513	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.064223549994474	[3]	[2,2]	-1	hSpCas9	positive selection	4257574
56386247	56386270	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.48181433532805035	[1]	[0,0]	-8	hSpCas9	positive selection	4257575
56383014	56383037	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-0.22875593621737844	[2]	[1,1]	-5	hSpCas9	positive selection	4257576
56383133	56383156	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.20669380816682575	[3]	[3,1]	-4	hSpCas9	positive selection	4321858
56384310	56384333	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.7734817956790281	[2]	[0,0]	-9	hSpCas9	positive selection	4321859
56382972	56382994	20	+	27760321	OCIAML3	viability	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-5.190984940792819	[200,158]	[5,0]	-9	hSpCas9	negative selection	4380896
56386248	56386270	20	+	27760321	OCIAML3	viability	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.6895622999872424	[678,578]	[267,350]	-6	hSpCas9	negative selection	4380897
56386365	56386387	20	-	27760321	OCIAML3	viability	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-0.46622489478706286	[461,375]	[225,248]	-5	hSpCas9	negative selection	4380898
56386394	56386416	20	+	27760321	OCIAML3	viability	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	0.12329141112341807	[525,514]	[463,418]	1	hSpCas9	negative selection	4380899
56386446	56386468	20	-	27760321	OCIAML3	viability	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	0.43091744870875304	[311,267]	[349,245]	5	hSpCas9	negative selection	4380900
56382972	56382994	20	+	27760321	OCIAML2	viability	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-1.9170405212718895	[200,158]	[33,43]	-9	hSpCas9	negative selection	4464359
56386248	56386270	20	+	27760321	OCIAML2	viability	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.0645246709123286	[678,578]	[210,283]	-7	hSpCas9	negative selection	4464360
56386365	56386387	20	-	27760321	OCIAML2	viability	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	0.060757745475665766	[461,375]	[267,461]	0	hSpCas9	negative selection	4464361
56386394	56386416	20	+	27760321	OCIAML2	viability	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	0.5075364983930449	[525,514]	[489,744]	7	hSpCas9	negative selection	4464362
56386446	56386468	20	-	27760321	OCIAML2	viability	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	0.1758387652910945	[311,267]	[230,307]	2	hSpCas9	negative selection	4464363
56382972	56382994	20	+	27760321	MV411	viability	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-1.875238064042615	[200,158]	[0,78]	-8	hSpCas9	negative selection	4547822
56386248	56386270	20	+	27760321	MV411	viability	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.641550293070899	[678,578]	[38,604]	-4	hSpCas9	negative selection	4547823
56386365	56386387	20	-	27760321	MV411	viability	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-0.8396122757638519	[461,375]	[46,313]	-5	hSpCas9	negative selection	4547824
56386394	56386416	20	+	27760321	MV411	viability	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	0.10762061448099502	[525,514]	[340,415]	0	hSpCas9	negative selection	4547825
56386446	56386468	20	-	27760321	MV411	viability	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	0.7099838765807999	[311,267]	[457,92]	5	hSpCas9	negative selection	4547826
56382972	56382994	20	+	27760321	HL60	viability	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-3.120979336323832	[200,158]	[9,23]	-9	hSpCas9	negative selection	4631285
56386248	56386270	20	+	27760321	HL60	viability	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.3900633813979162	[678,578]	[208,180]	-8	hSpCas9	negative selection	4631286
56386365	56386387	20	-	27760321	HL60	viability	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	1.9024440248312464	[461,375]	[1686,833]	9	hSpCas9	negative selection	4631287
56386394	56386416	20	+	27760321	HL60	viability	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	-0.4601997816516453	[525,514]	[319,298]	-5	hSpCas9	negative selection	4631288
56386446	56386468	20	-	27760321	HL60	viability	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	-0.42023831407561796	[311,267]	[93,263]	-5	hSpCas9	negative selection	4631289
56382972	56382994	20	+	27760321	HT1080	viability	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-3.4118250560883325	[158,123]	[0,9]	-7	hSpCas9	negative selection	4714748
56386248	56386270	20	+	27760321	HT1080	viability	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.5926500372403551	[578,451]	[69,65]	-5	hSpCas9	negative selection	4714749
56386365	56386387	20	-	27760321	HT1080	viability	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-3.61886785566949	[375,293]	[7,13]	-7	hSpCas9	negative selection	4714750
56386394	56386416	20	+	27760321	HT1080	viability	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	-0.5718910799445057	[514,401]	[172,67]	-3	hSpCas9	negative selection	4714751
56386446	56386468	20	-	27760321	HT1080	viability	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	-5.537648497522813	[267,208]	[2,0]	-8	hSpCas9	negative selection	4714752
56382972	56382994	20	+	27760321	HT29	viability after 7 days	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-1.5784805834175142	[158,123]	[50,29,98]	-9	hSpCas9	negative selection	4798211
56386248	56386270	20	+	27760321	HT29	viability after 7 days	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.6228783535755591	[578,451]	[444,427,419]	-7	hSpCas9	negative selection	4798212
56386365	56386387	20	-	27760321	HT29	viability after 7 days	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-0.8531011237415166	[375,293]	[287,318,118]	-8	hSpCas9	negative selection	4798213
56386394	56386416	20	+	27760321	HT29	viability after 7 days	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	-0.2654222608130765	[514,401]	[650,335,505]	-4	hSpCas9	negative selection	4798214
56386446	56386468	20	-	27760321	HT29	viability after 7 days	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	-0.9204944868058891	[267,208]	[129,150,198]	-8	hSpCas9	negative selection	4798215
56382972	56382994	20	+	27760321	HT29	viability after 25 days	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-4.744603361628519	[158,123]	[8,1,6]	-9	hSpCas9	negative selection	4881674
56386248	56386270	20	+	27760321	HT29	viability after 25 days	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.5133632722699404	[578,451]	[398,378,465]	-5	hSpCas9	negative selection	4881675
56386365	56386387	20	-	27760321	HT29	viability after 25 days	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-0.4839864209762898	[375,293]	[222,215,397]	-4	hSpCas9	negative selection	4881676
56386394	56386416	20	+	27760321	HT29	viability after 25 days	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	0.26886006919672545	[514,401]	[537,478,910]	2	hSpCas9	negative selection	4881677
56386446	56386468	20	-	27760321	HT29	viability after 25 days	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	-0.9118865270629406	[267,208]	[107,68,272]	-6	hSpCas9	negative selection	4881678
56382972	56382994	20	+	27760321	HT29	viability after 22 days	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-5.471515684502232	[158,123]	[5,0,3]	-9	hSpCas9	negative selection	4965137
56386248	56386270	20	+	27760321	HT29	viability after 22 days	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.29468995423554933	[578,451]	[503,470,481]	-3	hSpCas9	negative selection	4965138
56386365	56386387	20	-	27760321	HT29	viability after 22 days	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-0.653427536889813	[375,293]	[276,203,256]	-5	hSpCas9	negative selection	4965139
56386394	56386416	20	+	27760321	HT29	viability after 22 days	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	0.04555576151899232	[514,401]	[316,612,718]	0	hSpCas9	negative selection	4965140
56386446	56386468	20	-	27760321	HT29	viability after 22 days	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	-0.42551563513021673	[267,208]	[262,174,175]	-4	hSpCas9	negative selection	4965141
56382972	56382994	20	+	27760321	HT29	viability after 19 days	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-3.22097871836334	[158,123]	[48,5,0]	-9	hSpCas9	negative selection	5048600
56386248	56386270	20	+	27760321	HT29	viability after 19 days	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.3522527236053563	[578,451]	[558,738,110]	-3	hSpCas9	negative selection	5048601
56386365	56386387	20	-	27760321	HT29	viability after 19 days	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-0.7706348585428553	[375,293]	[185,188,291]	-6	hSpCas9	negative selection	5048602
56386394	56386416	20	+	27760321	HT29	viability after 19 days	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	0.4337759100307055	[514,401]	[771,700,659]	4	hSpCas9	negative selection	5048603
56386446	56386468	20	-	27760321	HT29	viability after 19 days	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	-0.6933787091826813	[267,208]	[176,59,265]	-5	hSpCas9	negative selection	5048604
56382972	56382994	20	+	27760321	HT29	viability after 16 days	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-3.4142159842521034	[158,123]	[36,0,8]	-9	hSpCas9	negative selection	5132063
56386248	56386270	20	+	27760321	HT29	viability after 16 days	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.5803687975508074	[578,451]	[325,518,302]	-5	hSpCas9	negative selection	5132064
56386365	56386387	20	-	27760321	HT29	viability after 16 days	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-0.23543947729948278	[375,293]	[257,143,551]	-3	hSpCas9	negative selection	5132065
56386394	56386416	20	+	27760321	HT29	viability after 16 days	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	-0.18267264864634616	[514,401]	[597,475,294]	-2	hSpCas9	negative selection	5132066
56386446	56386468	20	-	27760321	HT29	viability after 16 days	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	-0.08953076280509253	[267,208]	[295,117,345]	-1	hSpCas9	negative selection	5132067
56382972	56382994	20	+	27760321	HT29	viability after 13 days	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-2.6269021542743096	[158,123]	[53,4,20]	-9	hSpCas9	negative selection	5215526
56386248	56386270	20	+	27760321	HT29	viability after 13 days	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.0351915932890035	[578,451]	[297,227,345]	-7	hSpCas9	negative selection	5215527
56386365	56386387	20	-	27760321	HT29	viability after 13 days	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-0.4676225850418753	[375,293]	[332,193,313]	-5	hSpCas9	negative selection	5215528
56386394	56386416	20	+	27760321	HT29	viability after 13 days	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	-0.2770946348225115	[514,401]	[435,410,467]	-3	hSpCas9	negative selection	5215529
56386446	56386468	20	-	27760321	HT29	viability after 13 days	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	-0.6617806578539496	[267,208]	[93,173,251]	-6	hSpCas9	negative selection	5215530
56382972	56382994	20	+	27760321	HT29	viability after 10 days	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-3.3841086910572287	[158,123]	[2,47,0]	-9	hSpCas9	negative selection	5298989
56386248	56386270	20	+	27760321	HT29	viability after 10 days	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.6988210359351654	[578,451]	[539,421,231]	-7	hSpCas9	negative selection	5298990
56386365	56386387	20	-	27760321	HT29	viability after 10 days	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-0.44849784468684967	[375,293]	[397,233,285]	-5	hSpCas9	negative selection	5298991
56386394	56386416	20	+	27760321	HT29	viability after 10 days	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	-0.3140092755281333	[514,401]	[576,319,479]	-4	hSpCas9	negative selection	5298992
56386446	56386468	20	-	27760321	HT29	viability after 10 days	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	-0.8973322109073185	[267,208]	[185,216,79]	-7	hSpCas9	negative selection	5298993
56382972	56382994	20	+	27760321	MOLM13	viability	CCTGAAAACTCACCGAAGGTGG	AURKA	ENSG00000087586	-6.657010455083968	[200,158]	[0,0]	-9	hSpCas9	negative selection	5382452
56386248	56386270	20	+	27760321	MOLM13	viability	CTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.4284817376478463	[678,578]	[71,181]	-7	hSpCas9	negative selection	5382453
56386365	56386387	20	-	27760321	MOLM13	viability	CTTGTCTCCAGTCACAAGCCGG	AURKA	ENSG00000087586	-2.2806531951815967	[461,375]	[42,52]	-8	hSpCas9	negative selection	5382454
56386394	56386416	20	+	27760321	MOLM13	viability	GCTTGCAAAGGAATGCGCTGGG	AURKA	ENSG00000087586	0.2923220917957582	[525,514]	[252,451]	2	hSpCas9	negative selection	5382455
56386446	56386468	20	-	27760321	MOLM13	viability	TTACCTGTAAATAGTGGCCAGG	AURKA	ENSG00000087586	-0.7588157293391166	[311,267]	[63,123]	-5	hSpCas9	negative selection	5382456
56391679	56391702	20	+	27661255	K562	viability	GCCAGGACAAGGGCCTTCTTAGG	AURKA	ENSG00000087586	-1.4170139929030343	[497,533]	[151,155]	-9	dCas9-KRAB	negative selection	5464465
56391958	56391981	20	+	27661255	K562	viability	GTAACAAGCAGTATCCTACAGGG	AURKA	ENSG00000087586	-1.423520455038938	[1243,1292]	[424,336]	-9	dCas9-KRAB	negative selection	5464466
56391988	56392011	20	+	27661255	K562	viability	GTGCCCAGGAGCGGATGCAAAGG	AURKA	ENSG00000087586	-1.177599920130159	[379,427]	[150,134]	-8	dCas9-KRAB	negative selection	5464467
56392031	56392054	20	+	27661255	K562	viability	GCGCCAAGGACACTCAGGGACGG	AURKA	ENSG00000087586	-1.133367762386185	[36,21]	[12,8]	-8	dCas9-KRAB	negative selection	5464468
56391762	56391785	20	-	27661255	K562	viability	GTACGGAGAACTTGCAGCTGGGG	AURKA	ENSG00000087586	-1.539964426919399	[1323,1573]	[412,382]	-9	dCas9-KRAB	negative selection	5464469
56391779	56391802	20	-	27661255	K562	viability	GGAGACAGACGGTAAGCGTACGG	AURKA	ENSG00000087586	-1.448094190352351	[157,125]	[51,32]	-9	dCas9-KRAB	negative selection	5464470
56392124	56392147	20	-	27661255	K562	viability	GACCGTGGGGGATATCTCAGTGG	AURKA	ENSG00000087586	-0.9734958670632643	[652,620]	[348,182]	-8	dCas9-KRAB	negative selection	5464471
56392149	56392172	20	-	27661255	K562	viability	GCAGGTGGGAGCCGACGGGTGGG	AURKA	ENSG00000087586	-1.1649902534271108	[678,548]	[238,202]	-8	dCas9-KRAB	negative selection	5464472
56386490	56386513	20	+	27260156	BXPC3	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.6103419382278293	[780]	[529,478,561,573]	-8	hSpCas9	negative selection	5530034
56386247	56386270	20	+	27260156	BXPC3	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.0671637040621185	[192]	[90,99,129,59]	-9	hSpCas9	negative selection	5530035
56383014	56383037	20	+	27260156	BXPC3	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-0.9311682673151849	[296]	[164,109,200,179]	-9	hSpCas9	negative selection	5530036
56383133	56383156	20	-	27260156	BXPC3	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	0.22627225032874393	[625]	[758,556,922,843]	5	hSpCas9	negative selection	5594318
56384310	56384333	20	-	27260156	BXPC3	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.6358737470145261	[406]	[225,264,247,371]	-8	hSpCas9	negative selection	5594319
56386490	56386513	20	+	27260156	A673	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.669115293402595	[780]	[592,619,521,624]	-9	hSpCas9	negative selection	5651285
56386247	56386270	20	+	27260156	A673	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.7062334993375765	[192]	[125,130,138,171]	-9	hSpCas9	negative selection	5651286
56383014	56383037	20	+	27260156	A673	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-0.9693870075958484	[296]	[176,160,176,214]	-9	hSpCas9	negative selection	5651287
56383133	56383156	20	-	27260156	A673	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.38001663038495265	[625]	[596,525,589,600]	-7	hSpCas9	negative selection	5715569
56384310	56384333	20	-	27260156	A673	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.5950006993092258	[406]	[373,361,269,290]	-9	hSpCas9	negative selection	5715570
56386490	56386513	20	+	27260156	A375	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.8237677694598597	[780]	[597,612,470,404]	-8	hSpCas9	negative selection	5772536
56386247	56386270	20	+	27260156	A375	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.2407789496269428	[192]	[85,63,142,84]	-8	hSpCas9	negative selection	5772537
56383014	56383037	20	+	27260156	A375	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.882823181376111	[296]	[133,62,35,133]	-9	hSpCas9	negative selection	5772538
56383133	56383156	20	-	27260156	A375	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.29898250831694395	[625]	[846,711,478,380]	-4	hSpCas9	negative selection	5836820
56384310	56384333	20	-	27260156	A375	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.280257283389229	[406]	[327,212,71,174]	-9	hSpCas9	negative selection	5836821
56386490	56386513	20	+	27260156	COLO741	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.7036512885398964	[780]	[580,679,575]	-9	hSpCas9	negative selection	5893787
56386247	56386270	20	+	27260156	COLO741	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.616960685241289	[192]	[80,50,106]	-9	hSpCas9	negative selection	5893788
56383014	56383037	20	+	27260156	COLO741	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-0.7248837524992566	[296]	[166,270,243]	-9	hSpCas9	negative selection	5893789
56383133	56383156	20	-	27260156	COLO741	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.20111043427365655	[625]	[814,659,625]	-4	hSpCas9	negative selection	5958071
56384310	56384333	20	-	27260156	COLO741	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.323770445641002	[406]	[309,179,145]	-9	hSpCas9	negative selection	5958072
56386490	56386513	20	+	27260156	CAL120	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.5718123298221771	[780]	[807,664,513]	-7	hSpCas9	negative selection	6015038
56386247	56386270	20	+	27260156	CAL120	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.8726286237563474	[192]	[161,155,80]	-8	hSpCas9	negative selection	6015039
56383014	56383037	20	+	27260156	CAL120	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-2.3436576143023053	[296]	[59,56,98]	-9	hSpCas9	negative selection	6015040
56383133	56383156	20	-	27260156	CAL120	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.1445241549820115	[625]	[778,692,653]	-2	hSpCas9	negative selection	6079322
56384310	56384333	20	-	27260156	CAL120	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.7173135186196117	[406]	[469,204,273]	-7	hSpCas9	negative selection	6079323
56386490	56386513	20	+	27260156	CADOES1	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.991022537092082	[780]	[340,344,405,369]	-9	hSpCas9	negative selection	6136289
56386247	56386270	20	+	27260156	CADOES1	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.0136764036760904	[192]	[137,49,88,77]	-9	hSpCas9	negative selection	6136290
56383014	56383037	20	+	27260156	CADOES1	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.4081417161723164	[296]	[63,103,154,92]	-9	hSpCas9	negative selection	6136291
56383133	56383156	20	-	27260156	CADOES1	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	0.05960490148633368	[625]	[601,500,840,477]	1	hSpCas9	negative selection	6200573
56384310	56384333	20	-	27260156	CADOES1	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.8843372955507155	[406]	[223,209,186,198]	-9	hSpCas9	negative selection	6200574
56386490	56386513	20	+	27260156	EWS502	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.9320247920111661	[780]	[335,495,387,527]	-8	hSpCas9	negative selection	6257540
56386247	56386270	20	+	27260156	EWS502	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.3978139669020522	[192]	[72,64,68,105]	-9	hSpCas9	negative selection	6257541
56383014	56383037	20	+	27260156	EWS502	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.733180899694794	[296]	[29,139,78,137]	-9	hSpCas9	negative selection	6257542
56383133	56383156	20	-	27260156	EWS502	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.09265999962910787	[625]	[472,719,615,694]	-2	hSpCas9	negative selection	6321824
56384310	56384333	20	-	27260156	EWS502	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.5704134360478814	[406]	[111,215,117,133]	-9	hSpCas9	negative selection	6321825
56386490	56386513	20	+	27260156	EW8	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.8574437163469787	[780]	[275,336,342,432]	-9	hSpCas9	negative selection	6378791
56386247	56386270	20	+	27260156	EW8	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.7246555530847136	[192]	[48,37,66,31]	-9	hSpCas9	negative selection	6378792
56383014	56383037	20	+	27260156	EW8	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.9054893094043701	[296]	[73,49,62,70]	-9	hSpCas9	negative selection	6378793
56383133	56383156	20	-	27260156	EW8	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.4534114689591755	[625]	[410,488,240,366]	-7	hSpCas9	negative selection	6443075
56384310	56384333	20	-	27260156	EW8	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.3767033794733057	[406]	[133,169,95,113]	-9	hSpCas9	negative selection	6443076
56386490	56386513	20	+	27260156	CORL105	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.896761570345844	[780]	[556,436,506,468]	-9	hSpCas9	negative selection	6500042
56386247	56386270	20	+	27260156	CORL105	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.8355859814715243	[192]	[206,70,136,96]	-9	hSpCas9	negative selection	6500043
56383014	56383037	20	+	27260156	CORL105	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.5146287165894006	[296]	[143,132,87,116]	-9	hSpCas9	negative selection	6500044
56383133	56383156	20	-	27260156	CORL105	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.4015695809183646	[625]	[332,439,790,685]	-6	hSpCas9	negative selection	6564326
56384310	56384333	20	-	27260156	CORL105	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.9181370289835377	[406]	[125,236,302,345]	-9	hSpCas9	negative selection	6564327
56386490	56386513	20	+	27260156	HS294T	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-1.0355410457860668	[780]	[77,126,184,217]	-9	hSpCas9	negative selection	6621293
56386247	56386270	20	+	27260156	HS294T	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.271789310432821	[192]	[14,42,38,26]	-9	hSpCas9	negative selection	6621294
56383014	56383037	20	+	27260156	HS294T	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.6071815991680036	[296]	[21,24,55,51]	-9	hSpCas9	negative selection	6621295
56383133	56383156	20	-	27260156	HS294T	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.47617469799895856	[625]	[115,209,198,174]	-6	hSpCas9	negative selection	6685577
56384310	56384333	20	-	27260156	HS294T	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.666886777246823	[406]	[36,40,69,51]	-9	hSpCas9	negative selection	6685578
56386490	56386513	20	+	27260156	HCC44	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-1.1670182801584181	[780]	[433,218,404,537]	-9	hSpCas9	negative selection	6742544
56386247	56386270	20	+	27260156	HCC44	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.7398824572850782	[192]	[77,94,78,9]	-9	hSpCas9	negative selection	6742545
56383014	56383037	20	+	27260156	HCC44	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.4108139994159783	[296]	[34,199,173,85]	-9	hSpCas9	negative selection	6742546
56383133	56383156	20	-	27260156	HCC44	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.2150582947697836	[625]	[658,459,781,589]	-4	hSpCas9	negative selection	6806828
56384310	56384333	20	-	27260156	HCC44	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-2.18871982208921	[406]	[117,52,99,138]	-9	hSpCas9	negative selection	6806829
56386490	56386513	20	+	27260156	G402	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.8414323555075792	[780]	[1026,597,283,302]	-7	hSpCas9	negative selection	6863795
56386247	56386270	20	+	27260156	G402	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-2.0365353993520348	[192]	[95,61,14,61]	-9	hSpCas9	negative selection	6863796
56383014	56383037	20	+	27260156	G402	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-2.470576603440434	[296]	[23,83,95,52]	-9	hSpCas9	negative selection	6863797
56383133	56383156	20	-	27260156	G402	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	0.33822111006534067	[625]	[1768,654,655,880]	4	hSpCas9	negative selection	6928079
56384310	56384333	20	-	27260156	G402	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.7104679932479068	[406]	[142,121,71,260]	-9	hSpCas9	negative selection	6928080
56386490	56386513	20	+	27260156	L33	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.5439270794608367	[780]	[506,256,374,413]	-8	hSpCas9	negative selection	6985046
56386247	56386270	20	+	27260156	L33	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.9386736118500261	[192]	[78,51,50,115]	-9	hSpCas9	negative selection	6985047
56383014	56383037	20	+	27260156	L33	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-0.2972439121812297	[296]	[212,121,146,222]	-6	hSpCas9	negative selection	6985048
56383133	56383156	20	-	27260156	L33	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.1753047312768895	[625]	[506,237,345,579]	-4	hSpCas9	negative selection	7049330
56384310	56384333	20	-	27260156	L33	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.663394673199873	[406]	[288,104,174,203]	-9	hSpCas9	negative selection	7049331
56386490	56386513	20	+	27260156	K562	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-1.024380921268474	[780]	[317,425,485,155]	-8	hSpCas9	negative selection	7106297
56386247	56386270	20	+	27260156	K562	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-2.199169935546439	[192]	[49,14,56,27]	-9	hSpCas9	negative selection	7106298
56383014	56383037	20	+	27260156	K562	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-2.9449764971222336	[296]	[58,19,14,42]	-9	hSpCas9	negative selection	7106299
56383133	56383156	20	-	27260156	K562	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.22216374676286596	[625]	[733,485,241,463]	-3	hSpCas9	negative selection	7170581
56384310	56384333	20	-	27260156	K562	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.6139638885820502	[406]	[139,46,196,88]	-9	hSpCas9	negative selection	7170582
56386490	56386513	20	+	27260156	HT29	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.6258864762805814	[780]	[735,679,679,401]	-8	hSpCas9	negative selection	7227548
56386247	56386270	20	+	27260156	HT29	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.2702218911557213	[192]	[149,120,57,68]	-9	hSpCas9	negative selection	7227549
56383014	56383037	20	+	27260156	HT29	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.5242055966717476	[296]	[224,85,100,96]	-9	hSpCas9	negative selection	7227550
56383133	56383156	20	-	27260156	HT29	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	0.16751490298177535	[625]	[1109,1001,776,588]	3	hSpCas9	negative selection	7291832
56384310	56384333	20	-	27260156	HT29	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.734990610348037	[406]	[366,408,219,215]	-8	hSpCas9	negative selection	7291833
56386490	56386513	20	+	27260156	MHHES1	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.633355332850978	[780]	[658,510,658,457]	-8	hSpCas9	negative selection	7348799
56386247	56386270	20	+	27260156	MHHES1	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.19632682610655272	[192]	[215,108,281,151]	-4	hSpCas9	negative selection	7348800
56383014	56383037	20	+	27260156	MHHES1	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.5624388742682982	[296]	[160,32,139,113]	-9	hSpCas9	negative selection	7348801
56383133	56383156	20	-	27260156	MHHES1	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.6166580039456786	[625]	[619,568,459,257]	-8	hSpCas9	negative selection	7413083
56384310	56384333	20	-	27260156	MHHES1	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.2514434809385515	[406]	[122,366,140,152]	-9	hSpCas9	negative selection	7413084
56386490	56386513	20	+	27260156	MEWO	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.8289675081087978	[780]	[630,293,351]	-9	hSpCas9	negative selection	7470050
56386247	56386270	20	+	27260156	MEWO	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.5833851476547922	[192]	[122,115,122]	-8	hSpCas9	negative selection	7470051
56383014	56383037	20	+	27260156	MEWO	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-0.5903629505202079	[296]	[169,140,239]	-8	hSpCas9	negative selection	7470052
56383133	56383156	20	-	27260156	MEWO	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	0.21699764817543726	[625]	[749,769,534]	5	hSpCas9	negative selection	7534334
56384310	56384333	20	-	27260156	MEWO	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.3154443628860086	[406]	[224,132,114]	-9	hSpCas9	negative selection	7534335
56386490	56386513	20	+	27260156	LNCAPCLONEFGC	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-1.0862578727499879	[780]	[249,412,245,406]	-9	hSpCas9	negative selection	7591301
56386247	56386270	20	+	27260156	LNCAPCLONEFGC	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-2.0129074649569176	[192]	[44,56,47,22]	-9	hSpCas9	negative selection	7591302
56383014	56383037	20	+	27260156	LNCAPCLONEFGC	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.2315117282230916	[296]	[99,115,131,112]	-9	hSpCas9	negative selection	7591303
56383133	56383156	20	-	27260156	LNCAPCLONEFGC	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.47487512312061275	[625]	[298,524,426,377]	-6	hSpCas9	negative selection	7655585
56384310	56384333	20	-	27260156	LNCAPCLONEFGC	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.395650269481293	[406]	[119,71,164,211]	-9	hSpCas9	negative selection	7655586
56386490	56386513	20	+	27260156	PANC0327	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.2103121966519934	[780]	[857,317,622,656]	-3	hSpCas9	negative selection	7712552
56386247	56386270	20	+	27260156	PANC0327	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-2.1792582181713556	[192]	[36,39,14,58]	-9	hSpCas9	negative selection	7712553
56383014	56383037	20	+	27260156	PANC0327	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-2.0241618993220696	[296]	[60,50,112,35]	-9	hSpCas9	negative selection	7712554
56383133	56383156	20	-	27260156	PANC0327	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	0.3397219621839947	[625]	[575,658,751,822]	5	hSpCas9	negative selection	7776836
56384310	56384333	20	-	27260156	PANC0327	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.2964513353321454	[406]	[166,126,165,132]	-9	hSpCas9	negative selection	7776837
56386490	56386513	20	+	27260156	NCIH2009	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-1.3026678618335144	[780]	[433,365,525]	-8	hSpCas9	negative selection	7833803
56386247	56386270	20	+	27260156	NCIH2009	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-2.455495194563717	[192]	[36,48,58]	-9	hSpCas9	negative selection	7833804
56383014	56383037	20	+	27260156	NCIH2009	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-0.8970389993539465	[296]	[416,83,207]	-8	hSpCas9	negative selection	7833805
56383133	56383156	20	-	27260156	NCIH2009	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.8287634388291738	[625]	[360,351,739]	-7	hSpCas9	negative selection	7898087
56384310	56384333	20	-	27260156	NCIH2009	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.990958888601766	[406]	[173,89,171]	-9	hSpCas9	negative selection	7898088
56386490	56386513	20	+	27260156	NCIH1373	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-1.5358788892262563	[780]	[267,479,191,62]	-9	hSpCas9	negative selection	7955054
56386247	56386270	20	+	27260156	NCIH1373	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-3.16583274273197	[192]	[35,28,16,3]	-9	hSpCas9	negative selection	7955055
56383014	56383037	20	+	27260156	NCIH1373	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.6913517339429893	[296]	[93,159,100,11]	-9	hSpCas9	negative selection	7955056
56383133	56383156	20	-	27260156	NCIH1373	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.1974898625691642	[625]	[812,601,560,129]	-2	hSpCas9	negative selection	8019338
56384310	56384333	20	-	27260156	NCIH1373	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.5665020249784869	[406]	[108,66,581,123]	-5	hSpCas9	negative selection	8019339
56386490	56386513	20	+	27260156	PATU8902	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-1.1489215417497243	[780]	[532,654,386,398]	-7	hSpCas9	negative selection	8076305
56386247	56386270	20	+	27260156	PATU8902	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.4230053621841205	[192]	[38,181,47,151]	-8	hSpCas9	negative selection	8076306
56383014	56383037	20	+	27260156	PATU8902	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-4.4869323334632485	[296]	[48,5,12,4]	-9	hSpCas9	negative selection	8076307
56383133	56383156	20	-	27260156	PATU8902	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.6829783149025008	[625]	[812,409,192,878]	-6	hSpCas9	negative selection	8140589
56384310	56384333	20	-	27260156	PATU8902	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.4125552699206403	[406]	[412,348,475,451]	-4	hSpCas9	negative selection	8140590
56386490	56386513	20	+	27260156	PANC1	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-1.1801586266084847	[780]	[177,461,360,226]	-9	hSpCas9	negative selection	8197556
56386247	56386270	20	+	27260156	PANC1	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.7733437025468384	[192]	[46,65,76,12]	-9	hSpCas9	negative selection	8197557
56383014	56383037	20	+	27260156	PANC1	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-2.8208954606393384	[296]	[55,58,4,28]	-9	hSpCas9	negative selection	8197558
56383133	56383156	20	-	27260156	PANC1	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.5209688045821083	[625]	[381,487,350,305]	-7	hSpCas9	negative selection	8261840
56384310	56384333	20	-	27260156	PANC1	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.5549339040710375	[406]	[145,102,148,78]	-9	hSpCas9	negative selection	8261841
56386490	56386513	20	+	27260156	PANC0813	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-1.375130319100141	[780]	[408,432,350,232]	-9	hSpCas9	negative selection	8318807
56386247	56386270	20	+	27260156	PANC0813	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.9999198156890399	[192]	[92,122,97,135]	-8	hSpCas9	negative selection	8318808
56383014	56383037	20	+	27260156	PANC0813	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-2.48249088629402	[296]	[65,42,43,94]	-9	hSpCas9	negative selection	8318809
56383133	56383156	20	-	27260156	PANC0813	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.17299210156176378	[625]	[856,574,759,446]	-3	hSpCas9	negative selection	8383091
56384310	56384333	20	-	27260156	PANC0813	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.403661019308889	[406]	[207,180,156,178]	-9	hSpCas9	negative selection	8383092
56386490	56386513	20	+	27260156	RDES	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.9818271236023217	[780]	[441,483,478,388]	-9	hSpCas9	negative selection	8440058
56386247	56386270	20	+	27260156	RDES	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.5381899266412502	[192]	[50,79,77,103]	-9	hSpCas9	negative selection	8440059
56383014	56383037	20	+	27260156	RDES	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.7212031854603402	[296]	[74,68,94,195]	-9	hSpCas9	negative selection	8440060
56383133	56383156	20	-	27260156	RDES	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.267704114055344	[625]	[459,619,644,692]	-4	hSpCas9	negative selection	8504342
56384310	56384333	20	-	27260156	RDES	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.1125714040855466	[406]	[208,218,205,226]	-9	hSpCas9	negative selection	8504343
56386490	56386513	20	+	27260156	PC3	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.1360695267908777	[780]	[382,686,1247,813]	-3	hSpCas9	negative selection	8561309
56386247	56386270	20	+	27260156	PC3	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.5755297403096786	[192]	[55,37,117,63]	-9	hSpCas9	negative selection	8561310
56383014	56383037	20	+	27260156	PC3	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-0.6657375483887498	[296]	[94,144,193,349]	-9	hSpCas9	negative selection	8561311
56383133	56383156	20	-	27260156	PC3	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	0.21035437422767983	[625]	[419,887,1040,717]	4	hSpCas9	negative selection	8625593
56384310	56384333	20	-	27260156	PC3	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.9881765688789449	[406]	[74,201,365,285]	-9	hSpCas9	negative selection	8625594
56386490	56386513	20	+	27260156	PATU8988T	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.8555938229710545	[780]	[270,297,408,701]	-8	hSpCas9	negative selection	8682560
56386247	56386270	20	+	27260156	PATU8988T	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-2.3400084045490717	[192]	[59,28,28,27]	-9	hSpCas9	negative selection	8682561
56383014	56383037	20	+	27260156	PATU8988T	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.0168967508497833	[296]	[91,214,167,94]	-9	hSpCas9	negative selection	8682562
56383133	56383156	20	-	27260156	PATU8988T	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.746204786190249	[625]	[317,250,365,508]	-8	hSpCas9	negative selection	8746844
56384310	56384333	20	-	27260156	PATU8988T	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.2548184882222375	[406]	[183,131,213,121]	-9	hSpCas9	negative selection	8746845
56386490	56386513	20	+	27260156	T47D	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-1.1447136169036627	[780]	[432,338,455,423]	-9	hSpCas9	negative selection	8803811
56386247	56386270	20	+	27260156	T47D	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.3863304233697409	[192]	[89,67,67,120]	-9	hSpCas9	negative selection	8803812
56383014	56383037	20	+	27260156	T47D	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.8444503599636881	[296]	[97,94,105,85]	-9	hSpCas9	negative selection	8803813
56383133	56383156	20	-	27260156	T47D	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	0.11575895910511708	[625]	[821,760,794,784]	2	hSpCas9	negative selection	8868095
56384310	56384333	20	-	27260156	T47D	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.2588548174826641	[406]	[187,147,216,244]	-9	hSpCas9	negative selection	8868096
56386490	56386513	20	+	27260156	SU8686	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.6024320175644623	[780]	[497,469,536,543]	-7	hSpCas9	negative selection	8925062
56386247	56386270	20	+	27260156	SU8686	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-1.1864782319837766	[192]	[106,57,40,137]	-9	hSpCas9	negative selection	8925063
56383014	56383037	20	+	27260156	SU8686	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.9995649213304272	[296]	[69,92,31,99]	-9	hSpCas9	negative selection	8925064
56383133	56383156	20	-	27260156	SU8686	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.34475873427133225	[625]	[580,416,351,616]	-5	hSpCas9	negative selection	8989346
56384310	56384333	20	-	27260156	SU8686	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.586219493710976	[406]	[216,95,105,107]	-9	hSpCas9	negative selection	8989347
56386490	56386513	20	+	27260156	SKES1	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.7842816108830776	[780]	[505,527,463,336]	-9	hSpCas9	negative selection	9046313
56386247	56386270	20	+	27260156	SKES1	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.7898521355283175	[192]	[121,189,123,28]	-9	hSpCas9	negative selection	9046314
56383014	56383037	20	+	27260156	SKES1	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.2323577125531682	[296]	[206,193,67,61]	-9	hSpCas9	negative selection	9046315
56383133	56383156	20	-	27260156	SKES1	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.15761231622226257	[625]	[802,518,480,470]	-3	hSpCas9	negative selection	9110597
56384310	56384333	20	-	27260156	SKES1	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.2730851271230221	[406]	[181,230,165,107]	-9	hSpCas9	negative selection	9110598
56386490	56386513	20	+	27260156	TOV112D	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.8373520244573567	[780]	[608,554,312,319]	-9	hSpCas9	negative selection	9167564
56386247	56386270	20	+	27260156	TOV112D	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.7562509892634164	[192]	[74,214,110,78]	-9	hSpCas9	negative selection	9167565
56383014	56383037	20	+	27260156	TOV112D	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-0.8813399431930722	[296]	[119,206,187,138]	-9	hSpCas9	negative selection	9167566
56383133	56383156	20	-	27260156	TOV112D	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	0.037339739913546555	[625]	[986,480,466,626]	0	hSpCas9	negative selection	9231848
56384310	56384333	20	-	27260156	TOV112D	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.2172039251942315	[406]	[186,343,90,122]	-9	hSpCas9	negative selection	9231849
56386490	56386513	20	+	27260156	TC71	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.3545664622086857	[780]	[658,533,530,914]	-7	hSpCas9	negative selection	9288815
56386247	56386270	20	+	27260156	TC71	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.31960957395425904	[192]	[138,140,126,263]	-7	hSpCas9	negative selection	9288816
56383014	56383037	20	+	27260156	TC71	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-0.7690880621549177	[296]	[198,182,150,216]	-9	hSpCas9	negative selection	9288817
56383133	56383156	20	-	27260156	TC71	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	0.04416738015799243	[625]	[704,672,647,745]	1	hSpCas9	negative selection	9353099
56384310	56384333	20	-	27260156	TC71	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-0.7426681011861569	[406]	[254,237,249,302]	-9	hSpCas9	negative selection	9353100
56386490	56386513	20	+	27260156	TC32	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.6665605617910793	[780]	[433,342,591,527]	-8	hSpCas9	negative selection	9410066
56386247	56386270	20	+	27260156	TC32	viability	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-0.7959782813859582	[192]	[77,84,148,118]	-9	hSpCas9	negative selection	9410067
56383014	56383037	20	+	27260156	TC32	viability	TCTGAGCTGATGCTCCACTCCGG	AURKA	ENSG00000087586	-1.0090347279823386	[296]	[153,53,154,221]	-9	hSpCas9	negative selection	9410068
56383133	56383156	20	-	27260156	TC32	viability	CTTTGAAATTGGTCGCCCTCTGG	AURKA	ENSG00000087586	-0.40488932709858383	[625]	[591,247,527,452]	-6	hSpCas9	negative selection	9474350
56384310	56384333	20	-	27260156	TC32	viability	CCATATAGAAAATAATCCTGAGG	AURKA	ENSG00000087586	-1.086322640121924	[406]	[183,81,205,285]	-9	hSpCas9	negative selection	9474351
56370465	56370488	20	-	27869803	HPAFII	viability after 27 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.6030959173565671	[551]	[328,533,NaN]	5	hSpCas9	negative selection	9578261
56386247	56386270	20	+	27869803	HPAFII	viability after 27 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-4.800340000187496	[52]	[0,0,NaN]	-9	hSpCas9	negative selection	9578262
56386252	56386275	20	+	27869803	HPAFII	viability after 27 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.7352679351287498	[168]	[202,101,NaN]	6	hSpCas9	negative selection	9578263
56370465	56370488	20	-	27869803	HPAFII	viability after 15 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.11381560335992935	[551]	[977,432,NaN]	1	hSpCas9	negative selection	9660710
56386247	56386270	20	+	27869803	HPAFII	viability after 15 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-2.0608602985338456	[52]	[33,0,NaN]	-9	hSpCas9	negative selection	9660711
56386252	56386275	20	+	27869803	HPAFII	viability after 15 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.9069042798049787	[168]	[601,177,NaN]	8	hSpCas9	negative selection	9660712
56370465	56370488	20	-	27869803	ASPC1	viability after 36 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.9084973621241601	[1148]	[806,966,536]	8	hSpCas9	negative selection	9743159
56386247	56386270	20	+	27869803	ASPC1	viability after 36 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	0.10418534427446247	[118]	[105,1,34]	1	hSpCas9	negative selection	9743160
56386252	56386275	20	+	27869803	ASPC1	viability after 36 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	-1.0695601842733684	[559]	[107,117,61]	-7	hSpCas9	negative selection	9743161
56370465	56370488	20	-	27869803	PATU8988S	viability after 35 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.038534933992731335	[1025]	[383,464,NaN]	0	hSpCas9	negative selection	9825608
56386247	56386270	20	+	27869803	PATU8988S	viability after 35 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-4.077812008768344	[167]	[6,0,NaN]	-9	hSpCas9	negative selection	9825609
56386252	56386275	20	+	27869803	PATU8988S	viability after 35 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.9166145158981587	[347]	[295,232,NaN]	8	hSpCas9	negative selection	9825610
56370465	56370488	20	-	27869803	PATU8988S	viability after 31 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	-0.006498616532289447	[1025]	[368,455,NaN]	0	hSpCas9	negative selection	9908057
56386247	56386270	20	+	27869803	PATU8988S	viability after 31 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-2.2380772837476073	[167]	[11,16,NaN]	-9	hSpCas9	negative selection	9908058
56386252	56386275	20	+	27869803	PATU8988S	viability after 31 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.6758307571555374	[347]	[200,247,NaN]	7	hSpCas9	negative selection	9908059
56370465	56370488	20	-	27869803	HPAFII	viability after 35 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.4611229872985054	[551]	[236,550,NaN]	3	hSpCas9	negative selection	9990506
56386247	56386270	20	+	27869803	HPAFII	viability after 35 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-4.7458319015665245	[52]	[0,0,NaN]	-9	hSpCas9	negative selection	9990507
56386252	56386275	20	+	27869803	HPAFII	viability after 35 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.545213169653173	[168]	[169,73,NaN]	3	hSpCas9	negative selection	9990508
56370465	56370488	20	-	27869803	HPAFII	viability after 31 days	CGGGTAAGACGCAACTGAAAAGG	AURKA	ENSG00000087586	0.4291703616566409	[551]	[363,474,NaN]	3	hSpCas9	negative selection	10072955
56386247	56386270	20	+	27869803	HPAFII	viability after 31 days	GCTAGTTTACCAGGTGCCGATGG	AURKA	ENSG00000087586	-2.8489065893322287	[52]	[6,0,NaN]	-8	hSpCas9	negative selection	10072956
56386252	56386275	20	+	27869803	HPAFII	viability after 31 days	TTTACCAGGTGCCGATGGCAGGG	AURKA	ENSG00000087586	0.9753578106193194	[168]	[185,186,NaN]	7	hSpCas9	negative selection	10072957
56386392	56386415	20	+	28162770	P31FUJ	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	0.31316616469091385	[49]	[72]	3	hSpCas9	negative selection	10116431
56386490	56386513	20	+	28162770	P31FUJ	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.32730619087761315	[551]	[516]	-3	hSpCas9	negative selection	10116432
56386253	56386276	20	+	28162770	P31FUJ	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-1.9108741095270163	[319]	[99]	-8	hSpCas9	negative selection	10116433
56383028	56383051	20	-	28162770	P31FUJ	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-4.418668749725712	[181]	[9]	-9	hSpCas9	negative selection	10116434
56383117	56383140	20	+	28162770	P31FUJ	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-1.1694762690455496	[311]	[162]	-7	hSpCas9	negative selection	10116435
56370602	56370625	20	+	28162770	P31FUJ	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-1.5911984663710328	[640]	[249]	-7	hSpCas9	negative selection	10116436
56386301	56386324	20	+	28162770	P31FUJ	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-1.2328022044143785	[121]	[60]	-7	hSpCas9	negative selection	10116437
56383167	56383190	20	-	28162770	P31FUJ	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	-0.04465010749636322	[200]	[228]	0	hSpCas9	negative selection	10116438
56373512	56373535	20	+	28162770	P31FUJ	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-1.9586272409753842	[257]	[77]	-8	hSpCas9	negative selection	10116439
56386263	56386286	20	-	28162770	P31FUJ	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-2.003983513918498	[255]	[74]	-8	hSpCas9	negative selection	10116440
56386392	56386415	20	+	28162770	TF1	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10285797
56386490	56386513	20	+	28162770	TF1	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	NaN	[NaN]	[349]	1	hSpCas9	negative selection	10285798
56386253	56386276	20	+	28162770	TF1	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10285799
56383028	56383051	20	-	28162770	TF1	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10285800
56383117	56383140	20	+	28162770	TF1	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10285801
56370602	56370625	20	+	28162770	TF1	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10285802
56386301	56386324	20	+	28162770	TF1	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	NaN	[NaN]	[170]	1	hSpCas9	negative selection	10285803
56383167	56383190	20	-	28162770	TF1	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10285804
56373512	56373535	20	+	28162770	TF1	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10285805
56386263	56386286	20	-	28162770	TF1	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10285806
56386392	56386415	20	+	28162770	SKM1	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	-3.406964198743162	[17]	[2]	-9	hSpCas9	negative selection	10455163
56386490	56386513	20	+	28162770	SKM1	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.6051903089488573	[147]	[171]	-5	hSpCas9	negative selection	10455164
56386253	56386276	20	+	28162770	SKM1	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-0.8076464050449357	[99]	[100]	-6	hSpCas9	negative selection	10455165
56383028	56383051	20	-	28162770	SKM1	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-2.085036103855799	[47]	[19]	-8	hSpCas9	negative selection	10455166
56383117	56383140	20	+	28162770	SKM1	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-0.8941514837778408	[81]	[77]	-6	hSpCas9	negative selection	10455167
56370602	56370625	20	+	28162770	SKM1	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-2.790974802401381	[183]	[46]	-9	hSpCas9	negative selection	10455168
56386301	56386324	20	+	28162770	SKM1	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-2.3455636540790183	[45]	[15]	-8	hSpCas9	negative selection	10455169
56383167	56383190	20	-	28162770	SKM1	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	0.36386484728932844	[39]	[90]	3	hSpCas9	negative selection	10455170
56373512	56373535	20	+	28162770	SKM1	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-2.8220016980220057	[39]	[9]	-9	hSpCas9	negative selection	10455171
56386263	56386286	20	-	28162770	SKM1	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-2.259407010329304	[64]	[23]	-8	hSpCas9	negative selection	10455172
56386392	56386415	20	+	28162770	SKM1	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	-3.406964198743162	[17]	[2]	-9	hSpCas9	negative selection	10624529
56386490	56386513	20	+	28162770	SKM1	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.6051903089488573	[147]	[171]	-5	hSpCas9	negative selection	10624530
56386253	56386276	20	+	28162770	SKM1	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-0.8076464050449357	[99]	[100]	-6	hSpCas9	negative selection	10624531
56383028	56383051	20	-	28162770	SKM1	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-2.085036103855799	[47]	[19]	-8	hSpCas9	negative selection	10624532
56383117	56383140	20	+	28162770	SKM1	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-0.8941514837778408	[81]	[77]	-6	hSpCas9	negative selection	10624533
56370602	56370625	20	+	28162770	SKM1	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-2.790974802401381	[183]	[46]	-9	hSpCas9	negative selection	10624534
56386301	56386324	20	+	28162770	SKM1	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-2.3455636540790183	[45]	[15]	-8	hSpCas9	negative selection	10624535
56383167	56383190	20	-	28162770	SKM1	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	0.36386484728932844	[39]	[90]	3	hSpCas9	negative selection	10624536
56373512	56373535	20	+	28162770	SKM1	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-2.8220016980220057	[39]	[9]	-9	hSpCas9	negative selection	10624537
56386263	56386286	20	-	28162770	SKM1	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-2.259407010329304	[64]	[23]	-8	hSpCas9	negative selection	10624538
56386392	56386415	20	+	28162770	PL21	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	-0.8950176185510199	[46]	[10]	-6	hSpCas9	negative selection	10793895
56386490	56386513	20	+	28162770	PL21	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.132338399738952	[548]	[217]	-1	hSpCas9	negative selection	10793896
56386253	56386276	20	+	28162770	PL21	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-0.5934095080432534	[311]	[89]	-4	hSpCas9	negative selection	10793897
56383028	56383051	20	-	28162770	PL21	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-3.0562001387704654	[171]	[8]	-9	hSpCas9	negative selection	10793898
56383117	56383140	20	+	28162770	PL21	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-1.4348110220635126	[322]	[51]	-7	hSpCas9	negative selection	10793899
56370602	56370625	20	+	28162770	PL21	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-1.3685473465190054	[616]	[103]	-7	hSpCas9	negative selection	10793900
56386301	56386324	20	+	28162770	PL21	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-1.271166104436269	[121]	[21]	-7	hSpCas9	negative selection	10793901
56383167	56383190	20	-	28162770	PL21	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	-0.35928779412469836	[167]	[56]	-3	hSpCas9	negative selection	10793902
56373512	56373535	20	+	28162770	PL21	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-1.3210972886214487	[154]	[26]	-7	hSpCas9	negative selection	10793903
56386263	56386286	20	-	28162770	PL21	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-0.6702251050940846	[233]	[63]	-5	hSpCas9	negative selection	10793904
56386392	56386415	20	+	28162770	P31FUJ	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	0.31316616469091385	[49]	[72]	3	hSpCas9	negative selection	10963261
56386490	56386513	20	+	28162770	P31FUJ	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.32730619087761315	[551]	[516]	-3	hSpCas9	negative selection	10963262
56386253	56386276	20	+	28162770	P31FUJ	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-1.9108741095270163	[319]	[99]	-8	hSpCas9	negative selection	10963263
56383028	56383051	20	-	28162770	P31FUJ	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-4.418668749725712	[181]	[9]	-9	hSpCas9	negative selection	10963264
56383117	56383140	20	+	28162770	P31FUJ	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-1.1694762690455496	[311]	[162]	-7	hSpCas9	negative selection	10963265
56370602	56370625	20	+	28162770	P31FUJ	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-1.5911984663710328	[640]	[249]	-7	hSpCas9	negative selection	10963266
56386301	56386324	20	+	28162770	P31FUJ	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-1.2328022044143785	[121]	[60]	-7	hSpCas9	negative selection	10963267
56383167	56383190	20	-	28162770	P31FUJ	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	-0.04465010749636322	[200]	[228]	0	hSpCas9	negative selection	10963268
56373512	56373535	20	+	28162770	P31FUJ	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-1.9586272409753842	[257]	[77]	-8	hSpCas9	negative selection	10963269
56386263	56386286	20	-	28162770	P31FUJ	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-2.003983513918498	[255]	[74]	-8	hSpCas9	negative selection	10963270
56386392	56386415	20	+	28162770	OCIAML5	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	0.22972752029965027	[59]	[126]	2	hSpCas9	negative selection	11132627
56386490	56386513	20	+	28162770	OCIAML5	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	0.18308388427376798	[222]	[456]	1	hSpCas9	negative selection	11132628
56386253	56386276	20	+	28162770	OCIAML5	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-1.0761898802795609	[138]	[118]	-6	hSpCas9	negative selection	11132629
56383028	56383051	20	-	28162770	OCIAML5	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-4.406655422541634	[93]	[7]	-9	hSpCas9	negative selection	11132630
56383117	56383140	20	+	28162770	OCIAML5	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-1.1762648393761865	[158]	[126]	-6	hSpCas9	negative selection	11132631
56370602	56370625	20	+	28162770	OCIAML5	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-1.8328303520010796	[297]	[150]	-7	hSpCas9	negative selection	11132632
56386301	56386324	20	+	28162770	OCIAML5	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-1.0349306280138073	[83]	[73]	-6	hSpCas9	negative selection	11132633
56383167	56383190	20	-	28162770	OCIAML5	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	-0.1457977739207073	[94]	[154]	-1	hSpCas9	negative selection	11132634
56373512	56373535	20	+	28162770	OCIAML5	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-4.151626852722904	[127]	[12]	-9	hSpCas9	negative selection	11132635
56386263	56386286	20	-	28162770	OCIAML5	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-1.5316038849811333	[196]	[122]	-7	hSpCas9	negative selection	11132636
56386392	56386415	20	+	28162770	EOL1	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	-0.7535241335421028	[95]	[29]	-5	hSpCas9	negative selection	11301993
56386490	56386513	20	+	28162770	EOL1	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.21582488479401762	[603]	[273]	-2	hSpCas9	negative selection	11301994
56386253	56386276	20	+	28162770	EOL1	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-1.5844658759173234	[591]	[103]	-7	hSpCas9	negative selection	11301995
56383028	56383051	20	-	28162770	EOL1	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-5.225199347934147	[283]	[3]	-9	hSpCas9	negative selection	11301996
56383117	56383140	20	+	28162770	EOL1	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-1.0711002038897584	[661]	[165]	-6	hSpCas9	negative selection	11301997
56370602	56370625	20	+	28162770	EOL1	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-0.16677501334693257	[1075]	[504]	-1	hSpCas9	negative selection	11301998
56386301	56386324	20	+	28162770	EOL1	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-2.1478607239575154	[142]	[16]	-8	hSpCas9	negative selection	11301999
56383167	56383190	20	-	28162770	EOL1	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	-0.7736253395986126	[158]	[48]	-5	hSpCas9	negative selection	11302000
56373512	56373535	20	+	28162770	EOL1	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-1.9453916878650928	[211]	[28]	-8	hSpCas9	negative selection	11302001
56386263	56386286	20	-	28162770	EOL1	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-3.3812606579535505	[355]	[17]	-9	hSpCas9	negative selection	11302002
56386392	56386415	20	+	28162770	MOLM13	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	-0.8062855818944155	[103]	[42]	-4	hSpCas9	negative selection	11471359
56386490	56386513	20	+	28162770	MOLM13	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.41897164310468615	[759]	[410]	-3	hSpCas9	negative selection	11471360
56386253	56386276	20	+	28162770	MOLM13	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-1.7005642326810655	[489]	[108]	-7	hSpCas9	negative selection	11471361
56383028	56383051	20	-	28162770	MOLM13	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-5.2869981206188905	[215]	[3]	-9	hSpCas9	negative selection	11471362
56383117	56383140	20	+	28162770	MOLM13	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-1.5613225396719086	[448]	[109]	-6	hSpCas9	negative selection	11471363
56370602	56370625	20	+	28162770	MOLM13	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-1.9481608907073338	[949]	[177]	-7	hSpCas9	negative selection	11471364
56386301	56386324	20	+	28162770	MOLM13	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-2.139440932205032	[194]	[31]	-7	hSpCas9	negative selection	11471365
56383167	56383190	20	-	28162770	MOLM13	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	0.7116182645815815	[162]	[192]	5	hSpCas9	negative selection	11471366
56373512	56373535	20	+	28162770	MOLM13	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-4.480477850040099	[246]	[7]	-9	hSpCas9	negative selection	11471367
56386263	56386286	20	-	28162770	MOLM13	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-3.2439852316587965	[379]	[28]	-8	hSpCas9	negative selection	11471368
56386392	56386415	20	+	28162770	HEL	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	0.6427388320003569	[73]	[73]	5	hSpCas9	negative selection	11640725
56386490	56386513	20	+	28162770	HEL	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.5505866020220324	[605]	[264]	-4	hSpCas9	negative selection	11640726
56386253	56386276	20	+	28162770	HEL	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-3.584330076545564	[411]	[21]	-9	hSpCas9	negative selection	11640727
56383028	56383051	20	-	28162770	HEL	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-2.7888137540615037	[204]	[18]	-8	hSpCas9	negative selection	11640728
56383117	56383140	20	+	28162770	HEL	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-0.36529848706506135	[359]	[178]	-3	hSpCas9	negative selection	11640729
56370602	56370625	20	+	28162770	HEL	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-1.6538039444670918	[844]	[171]	-7	hSpCas9	negative selection	11640730
56386301	56386324	20	+	28162770	HEL	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-3.5448881711754145	[163]	[8]	-9	hSpCas9	negative selection	11640731
56383167	56383190	20	-	28162770	HEL	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	-0.9887662546578293	[188]	[60]	-6	hSpCas9	negative selection	11640732
56373512	56373535	20	+	28162770	HEL	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-3.3692338096657193	[241]	[14]	-9	hSpCas9	negative selection	11640733
56386263	56386286	20	-	28162770	HEL	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-2.299158213436075	[291]	[37]	-8	hSpCas9	negative selection	11640734
56386392	56386415	20	+	28162770	MV411	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	1.6932373038323059	[28]	[78]	9	hSpCas9	negative selection	11810091
56386490	56386513	20	+	28162770	MV411	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	0.3321347153580567	[429]	[455]	3	hSpCas9	negative selection	11810092
56386253	56386276	20	+	28162770	MV411	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-0.5936588538661645	[291]	[162]	-4	hSpCas9	negative selection	11810093
56383028	56383051	20	-	28162770	MV411	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-4.640087719958812	[147]	[4]	-9	hSpCas9	negative selection	11810094
56383117	56383140	20	+	28162770	MV411	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-1.2911549868003467	[397]	[136]	-7	hSpCas9	negative selection	11810095
56370602	56370625	20	+	28162770	MV411	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-1.4310873909298762	[636]	[198]	-7	hSpCas9	negative selection	11810096
56386301	56386324	20	+	28162770	MV411	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-1.0666710396452879	[91]	[36]	-6	hSpCas9	negative selection	11810097
56383167	56383190	20	-	28162770	MV411	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	0.7041530813114898	[144]	[198]	6	hSpCas9	negative selection	11810098
56373512	56373535	20	+	28162770	MV411	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-0.6911619045530814	[114]	[59]	-5	hSpCas9	negative selection	11810099
56386263	56386286	20	-	28162770	MV411	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-2.708168329858771	[255]	[32]	-9	hSpCas9	negative selection	11810100
56386392	56386415	20	+	28162770	MONOMAC1	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	0.8029631529404462	[21]	[43]	7	hSpCas9	negative selection	11979457
56386490	56386513	20	+	28162770	MONOMAC1	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.6228695493378917	[312]	[232]	-5	hSpCas9	negative selection	11979458
56386253	56386276	20	+	28162770	MONOMAC1	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-1.861070918771909	[224]	[70]	-8	hSpCas9	negative selection	11979459
56383028	56383051	20	-	28162770	MONOMAC1	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-0.9112823647256765	[104]	[63]	-6	hSpCas9	negative selection	11979460
56383117	56383140	20	+	28162770	MONOMAC1	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-0.6824636742297956	[244]	[174]	-5	hSpCas9	negative selection	11979461
56370602	56370625	20	+	28162770	MONOMAC1	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-2.0373801810710686	[375]	[104]	-8	hSpCas9	negative selection	11979462
56386301	56386324	20	+	28162770	MONOMAC1	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-1.1970368470595538	[69]	[34]	-7	hSpCas9	negative selection	11979463
56383167	56383190	20	-	28162770	MONOMAC1	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	-0.31251406447948976	[90]	[83]	-3	hSpCas9	negative selection	11979464
56373512	56373535	20	+	28162770	MONOMAC1	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-0.33643990372497024	[75]	[68]	-3	hSpCas9	negative selection	11979465
56386263	56386286	20	-	28162770	MONOMAC1	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-1.0760214460981876	[159]	[86]	-7	hSpCas9	negative selection	11979466
56386392	56386415	20	+	28162770	OCIAML2	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	0.48872819026049297	[8]	[69]	5	hSpCas9	negative selection	12148823
56386490	56386513	20	+	28162770	OCIAML2	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	-0.2722162668401531	[77]	[357]	-2	hSpCas9	negative selection	12148824
56386253	56386276	20	+	28162770	OCIAML2	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-1.2075954194083673	[59]	[143]	-7	hSpCas9	negative selection	12148825
56383028	56383051	20	-	28162770	OCIAML2	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-3.300704823799849	[31]	[17]	-9	hSpCas9	negative selection	12148826
56383117	56383140	20	+	28162770	OCIAML2	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-1.6734467082418485	[60]	[105]	-7	hSpCas9	negative selection	12148827
56370602	56370625	20	+	28162770	OCIAML2	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-1.7290549778233657	[124]	[208]	-8	hSpCas9	negative selection	12148828
56386301	56386324	20	+	28162770	OCIAML2	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	-1.5679270265970762	[22]	[42]	-7	hSpCas9	negative selection	12148829
56383167	56383190	20	-	28162770	OCIAML2	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	0.4811150061506177	[18]	[146]	4	hSpCas9	negative selection	12148830
56373512	56373535	20	+	28162770	OCIAML2	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-3.608133348992096	[32]	[14]	-9	hSpCas9	negative selection	12148831
56386263	56386286	20	-	28162770	OCIAML2	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-2.351985328743542	[34]	[37]	-8	hSpCas9	negative selection	12148832
56386392	56386415	20	+	28162770	OCIAML3	viability	GTGCTTGCAAAGGAATGCGCTGG	AURKA	ENSG00000087586	-2.786652718266559	[15]	[6]	-9	hSpCas9	negative selection	12318189
56386490	56386513	20	+	28162770	OCIAML3	viability	TGAGTCACGAGAACACGTTTTGG	AURKA	ENSG00000087586	0.21708968341925772	[109]	[385]	2	hSpCas9	negative selection	12318190
56386253	56386276	20	+	28162770	OCIAML3	viability	TTACCAGGTGCCGATGGCAGGGG	AURKA	ENSG00000087586	-1.6193187288533508	[114]	[112]	-8	hSpCas9	negative selection	12318191
56383028	56383051	20	-	28162770	OCIAML3	viability	TCAGCTGGAGAAAGCCGGAGTGG	AURKA	ENSG00000087586	-0.9454800108255408	[36]	[57]	-6	hSpCas9	negative selection	12318192
56383117	56383140	20	+	28162770	OCIAML3	viability	CCAAACTTTCCTTTACCCAGAGG	AURKA	ENSG00000087586	-0.7102006578286859	[83]	[154]	-5	hSpCas9	negative selection	12318193
56370602	56370625	20	+	28162770	OCIAML3	viability	CCGACCTTCAATCATTTCAGGGG	AURKA	ENSG00000087586	-2.137519697551816	[222]	[152]	-8	hSpCas9	negative selection	12318194
56386301	56386324	20	+	28162770	OCIAML3	viability	AGTGGCCTGGAGACAGGATGAGG	AURKA	ENSG00000087586	0.1479242067353923	[28]	[96]	1	hSpCas9	negative selection	12318195
56383167	56383190	20	-	28162770	OCIAML3	viability	AAATTCCTCCTAGGAGGCAGTGG	AURKA	ENSG00000087586	-0.009045139603007124	[25]	[77]	0	hSpCas9	negative selection	12318196
56373512	56373535	20	+	28162770	OCIAML3	viability	CTTCGAATGACAGTAAGACAGGG	AURKA	ENSG00000087586	-1.2278797415262659	[44]	[57]	-7	hSpCas9	negative selection	12318197
56386263	56386286	20	-	28162770	OCIAML3	viability	GAGCAAGCAGCCCCTGCCATCGG	AURKA	ENSG00000087586	-1.2664329822956586	[50]	[63]	-7	hSpCas9	negative selection	12318198