Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 10297
• Symbol: Apc2
• Description: APC regulator of WNT signaling pathway 2

DataSource: http://genomecrispr.dkfz.de/#!/results/Apc2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
1453028	1453051	19	+	26472758	Jiyoye	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-0.5292594897166605	[110]	[57]	-4	hSpCas9	negative selection	8032
1453297	1453320	19	+	26472758	Jiyoye	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	3.9921378822270293	[0]	[11]	9	hSpCas9	negative selection	8035
1453315	1453338	19	+	26472758	Jiyoye	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	-0.8968308053842265	[199]	[80]	-6	hSpCas9	negative selection	8036
1455164	1455187	19	+	26472758	Jiyoye	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-0.41225237285230576	[59]	[33]	-3	hSpCas9	negative selection	8037
1457076	1457099	19	-	26472758	Jiyoye	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	-0.3412858514981623	[125]	[74]	-2	hSpCas9	negative selection	8038
1461087	1461110	19	+	26472758	Jiyoye	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	0.020152258396626044	[203]	[155]	0	hSpCas9	negative selection	8039
1453028	1453051	19	+	26472758	KBM7	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-0.2785357844117206	[503,307]	[205,107]	-3	hSpCas9	negative selection	199150
1453297	1453320	19	+	26472758	KBM7	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	0.4060169612439335	[71,50]	[40,34]	4	hSpCas9	negative selection	199153
1453315	1453338	19	+	26472758	KBM7	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	0.10285797679463367	[472,375]	[233,193]	1	hSpCas9	negative selection	199154
1455164	1455187	19	+	26472758	KBM7	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-1.7895213617981152	[423,310]	[59,39]	-8	hSpCas9	negative selection	199155
1457076	1457099	19	-	26472758	KBM7	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	0.9372969891836851	[441,398]	[463,301]	8	hSpCas9	negative selection	199156
1461087	1461110	19	+	26472758	KBM7	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	0.504041018847093	[687,657]	[592,321]	5	hSpCas9	negative selection	199157
1453028	1453051	19	+	26472758	Raji	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-1.3049995104592664	[180]	[16]	-7	hSpCas9	negative selection	390268
1453297	1453320	19	+	26472758	Raji	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	1.6378982520723793	[17]	[12]	9	hSpCas9	negative selection	390271
1453315	1453338	19	+	26472758	Raji	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	0.7854554404862369	[139]	[55]	7	hSpCas9	negative selection	390272
1455164	1455187	19	+	26472758	Raji	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-3.127832926320432	[225]	[5]	-9	hSpCas9	negative selection	390273
1457076	1457099	19	-	26472758	Raji	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	0.4390050264648056	[177]	[55]	4	hSpCas9	negative selection	390274
1461087	1461110	19	+	26472758	Raji	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	-0.5141048413726707	[319]	[51]	-4	hSpCas9	negative selection	390275
1453028	1453051	19	+	26472758	K562	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-1.7759627723315738	[498]	[122]	-7	hSpCas9	negative selection	581386
1453297	1453320	19	+	26472758	K562	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-1.1593034583845625	[126]	[47]	-6	hSpCas9	negative selection	581389
1453315	1453338	19	+	26472758	K562	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	-1.478047296804644	[395]	[119]	-6	hSpCas9	negative selection	581390
1455164	1455187	19	+	26472758	K562	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-0.9986949840440869	[373]	[157]	-5	hSpCas9	negative selection	581391
1457076	1457099	19	-	26472758	K562	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	0.5305083697279063	[268]	[327]	4	hSpCas9	negative selection	581392
1461087	1461110	19	+	26472758	K562	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	-1.0943831857853117	[601]	[237]	-6	hSpCas9	negative selection	581393
1453070	1453093	19	-	26627737	DLD1	viability	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	6.4323060438968405	[1]	[101,45,18]	9	hSpCas9	negative selection	802906
1453420	1453443	19	+	26627737	DLD1	viability	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	0.09846477758550587	[1368]	[403,444,515]	1	hSpCas9	negative selection	802907
1455236	1455259	19	+	26627737	DLD1	viability	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.40074499805552893	[631]	[116,186,146]	-4	hSpCas9	negative selection	802909
1455479	1455502	19	+	26627737	DLD1	viability	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.7304746969706408	[505]	[119,52,108]	-6	hSpCas9	negative selection	802911
1456307	1456330	19	-	26627737	DLD1	viability	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	-0.18911684373526638	[1968]	[338,755,534]	-2	hSpCas9	negative selection	802916
1457048	1457071	19	-	26627737	DLD1	viability	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	-0.5094957889029041	[182]	[51,21,44]	-5	hSpCas9	negative selection	802917
1453070	1453093	19	-	26627737	GBM cells	viability after 5 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	0.12130629622213362	[53]	[17,44]	2	hSpCas9	negative selection	885221
1453420	1453443	19	+	26627737	GBM cells	viability after 5 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	0.08371393599379795	[921]	[448,598]	1	hSpCas9	negative selection	885222
1455236	1455259	19	+	26627737	GBM cells	viability after 5 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.0035308156916409004	[242]	[147,111]	0	hSpCas9	negative selection	885224
1455479	1455502	19	+	26627737	GBM cells	viability after 5 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	0.37788567991862815	[159]	[52,169]	6	hSpCas9	negative selection	885226
1456307	1456330	19	-	26627737	GBM cells	viability after 5 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.616183667710972	[766]	[610,649]	8	hSpCas9	negative selection	885231
1457048	1457071	19	-	26627737	GBM cells	viability after 5 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	-0.7177574855628088	[114]	[50,23]	-8	hSpCas9	negative selection	885232
1453070	1453093	19	-	26627737	GBM cells	viability after 13 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-0.22723189814939815	[53]	[13,33]	-3	hSpCas9	negative selection	967536
1453420	1453443	19	+	26627737	GBM cells	viability after 13 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.11160561120055723	[921]	[494,436]	-1	hSpCas9	negative selection	967537
1455236	1455259	19	+	26627737	GBM cells	viability after 13 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.20600922504924638	[242]	[169,68]	-2	hSpCas9	negative selection	967539
1455479	1455502	19	+	26627737	GBM cells	viability after 13 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	0.21323082955269568	[159]	[66,127]	2	hSpCas9	negative selection	967541
1456307	1456330	19	-	26627737	GBM cells	viability after 13 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.5249897408582422	[766]	[573,618]	6	hSpCas9	negative selection	967546
1457048	1457071	19	-	26627737	GBM cells	viability after 13 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	-0.0760767007269254	[114]	[99,25]	-1	hSpCas9	negative selection	967547
1453070	1453093	19	-	26627737	GBM cells	viability after 21 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	0.5862339483090035	[53]	[42,44]	6	hSpCas9	negative selection	1049851
1453420	1453443	19	+	26627737	GBM cells	viability after 21 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.5304757756674874	[921]	[339,352]	-5	hSpCas9	negative selection	1049852
1455236	1455259	19	+	26627737	GBM cells	viability after 21 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.449798451243557	[242]	[92,99]	-4	hSpCas9	negative selection	1049854
1455479	1455502	19	+	26627737	GBM cells	viability after 21 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	1.2502425433451352	[159]	[211,201]	9	hSpCas9	negative selection	1049856
1456307	1456330	19	-	26627737	GBM cells	viability after 21 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.2960229861069996	[766]	[520,502]	3	hSpCas9	negative selection	1049861
1457048	1457071	19	-	26627737	GBM cells	viability after 21 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	-0.0793570526361711	[114]	[55,61]	0	hSpCas9	negative selection	1049862
1453070	1453093	19	-	26627737	RPE1	viability after 9 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	0.17742576011379718	[116]	[64,10]	1	hSpCas9	negative selection	1132166
1453420	1453443	19	+	26627737	RPE1	viability after 9 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.6680308082446353	[2564]	[483,532]	-5	hSpCas9	negative selection	1132167
1455236	1455259	19	+	26627737	RPE1	viability after 9 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	0.26421922820766963	[718]	[189,373]	2	hSpCas9	negative selection	1132169
1455479	1455502	19	+	26627737	RPE1	viability after 9 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.4587744094458138	[877]	[106,319]	-3	hSpCas9	negative selection	1132171
1456307	1456330	19	-	26627737	RPE1	viability after 9 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	-0.10827509469121166	[4007]	[1129,1207]	-1	hSpCas9	negative selection	1132176
1457048	1457071	19	-	26627737	RPE1	viability after 9 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	1.274850543424462	[153]	[41,212]	7	hSpCas9	negative selection	1132177
1453070	1453093	19	-	26627737	RPE1	viability after 12 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-1.6237560608261337	[116]	[16,2]	-8	hSpCas9	negative selection	1214481
1453420	1453443	19	+	26627737	RPE1	viability after 12 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.2925926915313759	[2564]	[804,305]	-2	hSpCas9	negative selection	1214482
1455236	1455259	19	+	26627737	RPE1	viability after 12 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.40871956381359265	[718]	[162,126]	-3	hSpCas9	negative selection	1214484
1455479	1455502	19	+	26627737	RPE1	viability after 12 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.4272257945496451	[877]	[138,213]	-3	hSpCas9	negative selection	1214486
1456307	1456330	19	-	26627737	RPE1	viability after 12 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	-0.26248875547197104	[4007]	[869,926]	-2	hSpCas9	negative selection	1214491
1457048	1457071	19	-	26627737	RPE1	viability after 12 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	1.990892730773568	[153]	[43,291]	8	hSpCas9	negative selection	1214492
1453070	1453093	19	-	26627737	RPE1	viability after 15 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-2.85852303648998	[116]	[0,7]	-9	hSpCas9	negative selection	1296796
1453420	1453443	19	+	26627737	RPE1	viability after 15 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.3038604439007295	[2564]	[796,385]	-2	hSpCas9	negative selection	1296797
1455236	1455259	19	+	26627737	RPE1	viability after 15 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.44717913787606967	[718]	[138,158]	-3	hSpCas9	negative selection	1296799
1455479	1455502	19	+	26627737	RPE1	viability after 15 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	0.4501605493119049	[877]	[433,247]	3	hSpCas9	negative selection	1296801
1456307	1456330	19	-	26627737	RPE1	viability after 15 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	-0.17701055181284087	[4007]	[1544,479]	-1	hSpCas9	negative selection	1296806
1457048	1457071	19	-	26627737	RPE1	viability after 15 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	1.791723320478673	[153]	[47,249]	8	hSpCas9	negative selection	1296807
1453070	1453093	19	-	26627737	RPE1	viability after 18 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-2.94523932566576	[116]	[6,0]	-9	hSpCas9	negative selection	1379111
1453420	1453443	19	+	26627737	RPE1	viability after 18 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	0.10932197427245005	[2564]	[912,568]	0	hSpCas9	negative selection	1379112
1455236	1455259	19	+	26627737	RPE1	viability after 18 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.384318955835631	[718]	[196,96]	-2	hSpCas9	negative selection	1379114
1455479	1455502	19	+	26627737	RPE1	viability after 18 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	0.1011907719743656	[877]	[287,217]	0	hSpCas9	negative selection	1379116
1456307	1456330	19	-	26627737	RPE1	viability after 18 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	-0.10968362737622472	[4007]	[1204,785]	0	hSpCas9	negative selection	1379121
1457048	1457071	19	-	26627737	RPE1	viability after 18 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	2.263280874842026	[153]	[170,229]	9	hSpCas9	negative selection	1379122
1453070	1453093	19	-	26627737	HeLa	viability after 8 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	4.65698662269352	[0]	[7,23,0]	9	hSpCas9	negative selection	1461426
1453420	1453443	19	+	26627737	HeLa	viability after 8 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.7372583744328138	[1709]	[392,334,588]	-6	hSpCas9	negative selection	1461427
1455236	1455259	19	+	26627737	HeLa	viability after 8 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	1.0728205020622665	[301]	[240,370,213]	7	hSpCas9	negative selection	1461429
1455479	1455502	19	+	26627737	HeLa	viability after 8 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.030693346314697667	[453]	[210,89,276]	0	hSpCas9	negative selection	1461431
1456307	1456330	19	-	26627737	HeLa	viability after 8 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.14015376928042356	[1567]	[634,813,778]	1	hSpCas9	negative selection	1461436
1457048	1457071	19	-	26627737	HeLa	viability after 8 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	2.4571334232805837	[41]	[26,54,195]	9	hSpCas9	negative selection	1461437
1453070	1453093	19	-	26627737	HeLa	viability after 12 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	4.079572269915763	[0]	[11,7,0]	9	hSpCas9	negative selection	1543741
1453420	1453443	19	+	26627737	HeLa	viability after 12 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.30788574356512766	[1709]	[624,468,630]	-3	hSpCas9	negative selection	1543742
1455236	1455259	19	+	26627737	HeLa	viability after 12 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	1.244756371620621	[301]	[217,229,443]	8	hSpCas9	negative selection	1543744
1455479	1455502	19	+	26627737	HeLa	viability after 12 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.5734237159352578	[453]	[130,110,137]	-5	hSpCas9	negative selection	1543746
1456307	1456330	19	-	26627737	HeLa	viability after 12 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.4834280037163694	[1567]	[1045,536,1177]	4	hSpCas9	negative selection	1543751
1457048	1457071	19	-	26627737	HeLa	viability after 12 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	3.260488246422364	[41]	[148,104,250]	9	hSpCas9	negative selection	1543752
1453070	1453093	19	-	26627737	HeLa	viability after 15 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	4.278179234276032	[0]	[20,0,0]	9	hSpCas9	negative selection	1626056
1453420	1453443	19	+	26627737	HeLa	viability after 15 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.6852217317843272	[1709]	[460,397,439]	-6	hSpCas9	negative selection	1626057
1455236	1455259	19	+	26627737	HeLa	viability after 15 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	1.1468420449214771	[301]	[151,215,464]	7	hSpCas9	negative selection	1626059
1455479	1455502	19	+	26627737	HeLa	viability after 15 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	0.09035642579698905	[453]	[142,45,418]	0	hSpCas9	negative selection	1626061
1456307	1456330	19	-	26627737	HeLa	viability after 15 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.4244429393275784	[1567]	[1018,727,817]	3	hSpCas9	negative selection	1626066
1457048	1457071	19	-	26627737	HeLa	viability after 15 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	3.1478797262435743	[41]	[74,103,286]	9	hSpCas9	negative selection	1626067
1453070	1453093	19	-	26627737	HeLa	viability after 18 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	4.539205606276406	[0]	[16,0,0]	9	hSpCas9	negative selection	1708371
1453420	1453443	19	+	26627737	HeLa	viability after 18 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.7212311993967571	[1709]	[288,328,439]	-6	hSpCas9	negative selection	1708372
1455236	1455259	19	+	26627737	HeLa	viability after 18 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	1.206953794109216	[301]	[117,186,464]	8	hSpCas9	negative selection	1708374
1455479	1455502	19	+	26627737	HeLa	viability after 18 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	0.09254199930974882	[453]	[98,34,418]	0	hSpCas9	negative selection	1708376
1456307	1456330	19	-	26627737	HeLa	viability after 18 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.4308714742485744	[1567]	[706,582,817]	3	hSpCas9	negative selection	1708381
1457048	1457071	19	-	26627737	HeLa	viability after 18 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	3.137987981561494	[41]	[45,88,286]	9	hSpCas9	negative selection	1708382
1453070	1453093	19	-	26627737	HCT116	viability after 6 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-0.3756962593778588	[151]	[49,0]	-2	hSpCas9	negative selection	1790686
1453420	1453443	19	+	26627737	HCT116	viability after 6 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	1.104205358578012	[1303]	[742,273]	6	hSpCas9	negative selection	1790687
1455236	1455259	19	+	26627737	HCT116	viability after 6 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-1.7143445792427876	[1013]	[45,49]	-7	hSpCas9	negative selection	1790689
1455479	1455502	19	+	26627737	HCT116	viability after 6 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-2.1814293736262877	[549]	[49,1]	-8	hSpCas9	negative selection	1790691
1456307	1456330	19	-	26627737	HCT116	viability after 6 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.9364602173045484	[1885]	[1298,163]	5	hSpCas9	negative selection	1790696
1457048	1457071	19	-	26627737	HCT116	viability after 6 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	3.2403731281201087	[20]	[36,27]	9	hSpCas9	negative selection	1790697
1453070	1453093	19	-	26627737	HCT116	viability after 8 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-1.333431396853614	[62]	[7,0,31]	-9	hSpCas9	negative selection	1873001
1453420	1453443	19	+	26627737	HCT116	viability after 8 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	0.3430709843157973	[881]	[748,420,680]	4	hSpCas9	negative selection	1873002
1455236	1455259	19	+	26627737	HCT116	viability after 8 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.5106078457959673	[483]	[190,127,241]	-6	hSpCas9	negative selection	1873004
1455479	1455502	19	+	26627737	HCT116	viability after 8 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.08827569474335158	[277]	[182,107,141]	-1	hSpCas9	negative selection	1873006
1456307	1456330	19	-	26627737	HCT116	viability after 8 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.06413163969085911	[984]	[510,598,590]	0	hSpCas9	negative selection	1873011
1457048	1457071	19	-	26627737	HCT116	viability after 8 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	3.255526836627878	[15]	[92,95,63]	9	hSpCas9	negative selection	1873012
1453070	1453093	19	-	26627737	HCT116	viability after 9 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-1.3028825184560007	[151]	[35,0]	-7	hSpCas9	negative selection	1955316
1453420	1453443	19	+	26627737	HCT116	viability after 9 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	0.8591989826098163	[1303]	[906,413]	6	hSpCas9	negative selection	1955317
1455236	1455259	19	+	26627737	HCT116	viability after 9 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.596092722504496	[1013]	[177,179]	-4	hSpCas9	negative selection	1955319
1455479	1455502	19	+	26627737	HCT116	viability after 9 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.1420386553439198	[549]	[12,227]	-1	hSpCas9	negative selection	1955321
1456307	1456330	19	-	26627737	HCT116	viability after 9 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.027248145691511683	[1885]	[682,378]	0	hSpCas9	negative selection	1955326
1457048	1457071	19	-	26627737	HCT116	viability after 9 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	4.208856735244195	[20]	[139,74]	9	hSpCas9	negative selection	1955327
1453070	1453093	19	-	26627737	HCT116	viability after 12 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-1.514237401577601	[62]	[7,7,18]	-9	hSpCas9	negative selection	2037631
1453420	1453443	19	+	26627737	HCT116	viability after 12 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.0336313636334169	[881]	[515,495,341]	0	hSpCas9	negative selection	2037632
1455236	1455259	19	+	26627737	HCT116	viability after 12 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.4314674715792855	[483]	[149,179,238]	-5	hSpCas9	negative selection	2037634
1455479	1455502	19	+	26627737	HCT116	viability after 12 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.1532686377555862	[277]	[95,80,218]	-1	hSpCas9	negative selection	2037636
1456307	1456330	19	-	26627737	HCT116	viability after 12 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	-0.11715457050046885	[984]	[592,491,336]	-1	hSpCas9	negative selection	2037641
1457048	1457071	19	-	26627737	HCT116	viability after 12 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	2.9702631752289506	[15]	[73,66,55]	9	hSpCas9	negative selection	2037642
1453070	1453093	19	-	26627737	HCT116	viability after 15 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-1.5208974657840417	[62]	[14,0,21]	-8	hSpCas9	negative selection	2119946
1453420	1453443	19	+	26627737	HCT116	viability after 15 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	0.10585601043782278	[881]	[763,442,455]	1	hSpCas9	negative selection	2119947
1455236	1455259	19	+	26627737	HCT116	viability after 15 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.8152379820682034	[483]	[271,158,57]	-7	hSpCas9	negative selection	2119949
1455479	1455502	19	+	26627737	HCT116	viability after 15 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.38404370683684563	[277]	[62,190,105]	-4	hSpCas9	negative selection	2119951
1456307	1456330	19	-	26627737	HCT116	viability after 15 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	-0.05799169814064031	[984]	[593,553,488]	0	hSpCas9	negative selection	2119956
1457048	1457071	19	-	26627737	HCT116	viability after 15 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	3.5196803259416356	[15]	[36,178,91]	9	hSpCas9	negative selection	2119957
1453070	1453093	19	-	26627737	HCT116	viability after 18 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-1.7545746803535929	[62]	[0,12,12]	-8	hSpCas9	negative selection	2202261
1453420	1453443	19	+	26627737	HCT116	viability after 18 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	0.3287807141392429	[881]	[770,469,361]	3	hSpCas9	negative selection	2202262
1455236	1455259	19	+	26627737	HCT116	viability after 18 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.09509052529516238	[483]	[138,304,206]	-1	hSpCas9	negative selection	2202264
1455479	1455502	19	+	26627737	HCT116	viability after 18 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-1.2578062041564348	[277]	[57,34,77]	-8	hSpCas9	negative selection	2202266
1456307	1456330	19	-	26627737	HCT116	viability after 18 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.28205474215607285	[984]	[606,473,666]	2	hSpCas9	negative selection	2202271
1457048	1457071	19	-	26627737	HCT116	viability after 18 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	3.3801020261535615	[15]	[95,27,122]	9	hSpCas9	negative selection	2202272
1449979	1450002	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGGCGTCGGGCCTCCGCGCGG	APC2	ENSG00000115266	0.7401414881086603	[28,8]	[3,9]	3	dCas9-VP64	positive selection	2438813
1450023	1450046	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAACAGCCAATGGCGGCCCGG	APC2	ENSG00000115266	0.1678458859794386	[72,11]	[14,4]	0	dCas9-VP64	positive selection	2438814
1450044	1450067	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAAGACGGGCTGGTGCCATGG	APC2	ENSG00000115266	-1.4082003353718104	[180,162]	[21,4]	-7	dCas9-VP64	positive selection	2438815
1449979	1450002	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGGCGTCGGGCCTCCGCGCGG	APC2	ENSG00000115266	0.5629773483109752	[20,41]	[9,18]	4	dCas9-VP64	positive selection	2534068
1450023	1450046	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAACAGCCAATGGCGGCCCGG	APC2	ENSG00000115266	-0.4084792223557092	[58,43]	[10,13]	-4	dCas9-VP64	positive selection	2534069
1450044	1450067	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAAGACGGGCTGGTGCCATGG	APC2	ENSG00000115266	-0.1149015171028154	[134,106]	[29,41]	-1	dCas9-VP64	positive selection	2534070
1456991	1457014	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAATCCTCCACGGCACCGAGG	APC2	ENSG00000115266	0.1288000801324618	[4,3]	[4,2]	2	hSpCas9	positive selection	2970880
1453500	1453523	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCCCTCGGGGGTCCGGGCGG	APC2	ENSG00000115266	-0.3949475642020255	[2,2]	[1,1]	-5	hSpCas9	positive selection	2970881
1456991	1457014	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAATCCTCCACGGCACCGAGG	APC2	ENSG00000115266	0.03163715581926521	[4,4]	[3,2]	0	hSpCas9	positive selection	3038738
1453500	1453523	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCCCTCGGGGGTCCGGGCGG	APC2	ENSG00000115266	-0.08789607717932241	[2,2]	[2,0]	-1	hSpCas9	positive selection	3038739
1453465	1453488		+	24336571	A375	resistance to PLX after 7 days	CAAGTTCCAGCCGCCCACCCTGG	APC2	ENSG00000115266	-0.05563368633075805	[26,35]	[29,29]	-1	hSpCas9	positive selection	3122832
1453303	1453326		+	24336571	A375	resistance to PLX after 7 days	CTCGGGGCAGACGGAGGTGCTGG	APC2	ENSG00000115266	-0.07023111909737378	[7,11]	[9,7]	-2	hSpCas9	positive selection	3122841
1453518	1453541		+	24336571	A375	resistance to PLX after 7 days	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.14383387421326932	[12,12]	[13,14]	4	hSpCas9	positive selection	3122842
1453276	1453299		+	24336571	A375	resistance to PLX after 7 days	GGAGCAGGAGGCCCGAGTGCTGG	APC2	ENSG00000115266	0.15935408691805986	[2,1]	[2,2]	5	hSpCas9	positive selection	3122852
1453465	1453488		+	24336571	A375	resistance to PLX after 14 days	CAAGTTCCAGCCGCCCACCCTGG	APC2	ENSG00000115266	-1.2060436000403643	[32,38]	[6,6]	-9	hSpCas9	positive selection	3180625
1453303	1453326		+	24336571	A375	resistance to PLX after 14 days	CTCGGGGCAGACGGAGGTGCTGG	APC2	ENSG00000115266	0.20736891663348606	[6,9]	[3,4]	2	hSpCas9	positive selection	3180634
1453518	1453541		+	24336571	A375	resistance to PLX after 14 days	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.3548486537933499	[8,11]	[5,6]	3	hSpCas9	positive selection	3180635
1453276	1453299		+	24336571	A375	resistance to PLX after 14 days	GGAGCAGGAGGCCCGAGTGCTGG	APC2	ENSG00000115266	0.05959827414343666	[3,3]	[1,1]	0	hSpCas9	positive selection	3180645
1453465	1453488		+	24336571	A375	viability after 7 days	CAAGTTCCAGCCGCCCACCCTGG	APC2	ENSG00000115266	0.12574716395741392	[29]	[26,35]	2	hSpCas9	negative selection	3238418
1453303	1453326		+	24336571	A375	viability after 7 days	CTCGGGGCAGACGGAGGTGCTGG	APC2	ENSG00000115266	0.33024000357487926	[7]	[7,11]	5	hSpCas9	negative selection	3238427
1453518	1453541		+	24336571	A375	viability after 7 days	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.14983458217009987	[14]	[12,12]	-2	hSpCas9	negative selection	3238428
1453276	1453299		+	24336571	A375	viability after 7 days	GGAGCAGGAGGCCCGAGTGCTGG	APC2	ENSG00000115266	0.18620067847037136	[1]	[2,1]	3	hSpCas9	negative selection	3238438
1453465	1453488		+	24336571	A375	viability after 14 days	CAAGTTCCAGCCGCCCACCCTGG	APC2	ENSG00000115266	0.3411939080859496	[29]	[32,38]	4	hSpCas9	negative selection	3296211
1453303	1453326		+	24336571	A375	viability after 14 days	CTCGGGGCAGACGGAGGTGCTGG	APC2	ENSG00000115266	0.22023259414503316	[7]	[6,9]	3	hSpCas9	negative selection	3296220
1453518	1453541		+	24336571	A375	viability after 14 days	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.41999668322754746	[14]	[8,11]	-5	hSpCas9	negative selection	3296221
1453276	1453299		+	24336571	A375	viability after 14 days	GGAGCAGGAGGCCCGAGTGCTGG	APC2	ENSG00000115266	0.7401477566551742	[1]	[3,3]	8	hSpCas9	negative selection	3296231
1455464	1455487	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	3.7996100449023196	[8,12]	[0,0]	9	hSpCas9	positive selection	3336964
1455218	1455241	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	5.448624863680714	[3,2]	[0,0]	9	hSpCas9	positive selection	3336965
1453522	1453545	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	2.3055653437827397	[22,38]	[0,0]	8	hSpCas9	positive selection	3336966
1455443	1455466	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.25046842875286124	[181,181]	[0,0]	-1	hSpCas9	positive selection	3356211
1455243	1455266	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.7426737885541649	[255,255]	[0,0]	-5	hSpCas9	positive selection	3356212
1453518	1453541	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.10899600279998067	[164,164]	[0,0]	0	hSpCas9	positive selection	3356213
1456990	1457013	19	+	26780180	HT29	viability (Avana library 4 designs)	GCAAATCCTCCACGGCACCGAGG	APC2	ENSG00000115266	0.354707902790352	[]	[]	1	hSpCas9	negative selection	3406982
1453500	1453523	19	-	26780180	HT29	viability (Avana library 4 designs)	GCTGCCCTCGGGGGTCCGGGCGG	APC2	ENSG00000115266	1.21955874024051	[]	[]	5	hSpCas9	negative selection	3406983
1453500	1453523	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCCTCGGGGGTCCGGGCGG	APC2	ENSG00000115266	2.23607845424624	[]	[]	3	hSpCas9	negative selection	3479810
1456990	1457013	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAATCCTCCACGGCACCGAGG	APC2	ENSG00000115266	4.97827464549456	[]	[]	8	hSpCas9	negative selection	3479811
1456963	1456986	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGAGGCAGACAGCCCGAGCGG	APC2	ENSG00000115266	3.87368686315609	[]	[]	6	hSpCas9	negative selection	3479812
1453500	1453523	19	-	26780180	A375	viability (Avana lentiGuide)	GCTGCCCTCGGGGGTCCGGGCGG	APC2	ENSG00000115266	5.76512009231	[]	[]	5	hSpCas9	negative selection	3588469
1456990	1457013	19	+	26780180	A375	viability (Avana lentiGuide)	GCAAATCCTCCACGGCACCGAGG	APC2	ENSG00000115266	-0.246998827760073	[]	[]	0	hSpCas9	negative selection	3588470
1456963	1456986	19	-	26780180	A375	viability (Avana lentiGuide)	GCAGAGGCAGACAGCCCGAGCGG	APC2	ENSG00000115266	5.08089189376728	[]	[]	4	hSpCas9	negative selection	3588471
1453500	1453523	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCCTCGGGGGTCCGGGCGG	APC2	ENSG00000115266	0.3242986989967733	[3]	[4,4]	8	hSpCas9	positive selection	3697128
1456990	1457013	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAATCCTCCACGGCACCGAGG	APC2	ENSG00000115266	0.1582731923537205	[5]	[6,5]	4	hSpCas9	positive selection	3697129
1456963	1456986	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGAGGCAGACAGCCCGAGCGG	APC2	ENSG00000115266	0.18906758084978192	[4]	[5,3]	5	hSpCas9	positive selection	3697130
1453500	1453523	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCCTCGGGGGTCCGGGCGG	APC2	ENSG00000115266	-0.39600308368041504	[5]	[3,2]	-5	hSpCas9	positive selection	3805735
1456990	1457013	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAATCCTCCACGGCACCGAGG	APC2	ENSG00000115266	0.22927883813911165	[6]	[6,5]	6	hSpCas9	positive selection	3805736
1456963	1456986	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGAGGCAGACAGCCCGAGCGG	APC2	ENSG00000115266	0.24056548504264064	[4]	[3,5]	6	hSpCas9	positive selection	3805737
1455443	1455466	19	-	26780180	A375	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	1.14186886180313	[]	[]	6	hSpCas9	negative selection	3913978
1453522	1453545	19	-	26780180	A375	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.384448970738815	[]	[]	0	hSpCas9	negative selection	3913979
1455243	1455266	19	-	26780180	A375	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	1.22439114964769	[]	[]	6	hSpCas9	negative selection	3913980
1455464	1455487	19	+	26780180	A375	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.22383196337812	[]	[]	0	hSpCas9	negative selection	3913981
1453518	1453541	19	+	26780180	A375	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	1.40471547512418	[]	[]	7	hSpCas9	negative selection	3913982
1455218	1455241	19	-	26780180	A375	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	0.191465407297447	[]	[]	0	hSpCas9	negative selection	3913983
1455443	1455466	19	-	26780180	HT29	viability (GeCKOv2 library)	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.949046892033234	[]	[]	4	hSpCas9	negative selection	4021944
1453522	1453545	19	-	26780180	HT29	viability (GeCKOv2 library)	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	1.36850352484151	[]	[]	7	hSpCas9	negative selection	4021945
1455243	1455266	19	-	26780180	HT29	viability (GeCKOv2 library)	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	1.75099970050338	[]	[]	8	hSpCas9	negative selection	4021946
1455464	1455487	19	+	26780180	HT29	viability (GeCKOv2 library)	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.4926634528687	[]	[]	1	hSpCas9	negative selection	4021947
1453518	1453541	19	+	26780180	HT29	viability (GeCKOv2 library)	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	1.43472900862501	[]	[]	7	hSpCas9	negative selection	4021948
1455218	1455241	19	-	26780180	HT29	viability (GeCKOv2 library)	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	0.427537266942275	[]	[]	1	hSpCas9	negative selection	4021949
1453465	1453488	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAAGTTCCAGCCGCCCACCCTGG	APC2	ENSG00000115266	-0.030623007040360417	[4]	[3,2]	0	hSpCas9	positive selection	4146643
1453303	1453326	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCGGGGCAGACGGAGGTGCTGG	APC2	ENSG00000115266	-0.008312312203276356	[3]	[1,1]	0	hSpCas9	positive selection	4146654
1453518	1453541	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.0035061682508153724	[4]	[2,2]	0	hSpCas9	positive selection	4146665
1453276	1453299	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAGCAGGAGGCCCGAGTGCTGG	APC2	ENSG00000115266	0.050938474063172645	[0]	[0,0]	1	hSpCas9	positive selection	4146676
1453465	1453488	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAAGTTCCAGCCGCCCACCCTGG	APC2	ENSG00000115266	0.6564979044953354	[4]	[1,2,3,3]	4	hSpCas9	positive selection	4210665
1453303	1453326	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCGGGGCAGACGGAGGTGCTGG	APC2	ENSG00000115266	0.5248221842116741	[1]	[0,0,3,0]	3	hSpCas9	positive selection	4210676
1453518	1453541	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.4368266296727679	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4210687
1453276	1453299	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAGCAGGAGGCCCGAGTGCTGG	APC2	ENSG00000115266	-0.2128564613603281	[1]	[0,0,0,0]	-3	hSpCas9	positive selection	4210698
1455464	1455487	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.21173287327676937	[0]	[0,0]	4	hSpCas9	positive selection	4256093
1455218	1455241	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-0.0282984385587719	[0]	[0,0]	0	hSpCas9	positive selection	4256094
1453522	1453545	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	-0.35337153287363343	[1]	[1,0]	-6	hSpCas9	positive selection	4256095
1455443	1455466	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.5629721811367397	[2]	[2,3]	9	hSpCas9	positive selection	4320377
1455243	1455266	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	0.14458691835638698	[3]	[2,2]	3	hSpCas9	positive selection	4320378
1453518	1453541	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.27233930071948614	[2]	[2,2]	5	hSpCas9	positive selection	4320379
1455465	1455487	19	+	27760321	OCIAML3	viability	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.5972676677841919	[384,347]	[378,503]	7	hSpCas9	negative selection	4378593
1456878	1456900	19	-	27760321	OCIAML3	viability	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-0.7220913366501033	[644,625]	[195,439]	-6	hSpCas9	negative selection	4378594
1456949	1456971	19	+	27760321	OCIAML3	viability	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	0.10049026356999946	[832,782]	[687,664]	1	hSpCas9	negative selection	4378595
1455465	1455487	19	+	27760321	OCIAML2	viability	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.3346546761015825	[384,347]	[269,509]	4	hSpCas9	negative selection	4462056
1456878	1456900	19	-	27760321	OCIAML2	viability	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-0.7323089484352157	[644,625]	[275,354]	-6	hSpCas9	negative selection	4462057
1456949	1456971	19	+	27760321	OCIAML2	viability	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	0.21597646877944554	[832,782]	[606,960]	3	hSpCas9	negative selection	4462058
1455465	1455487	19	+	27760321	MV411	viability	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-1.4617843427068657	[384,347]	[0,217]	-7	hSpCas9	negative selection	4545519
1456878	1456900	19	-	27760321	MV411	viability	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-2.2656973037690995	[644,625]	[70,111]	-8	hSpCas9	negative selection	4545520
1456949	1456971	19	+	27760321	MV411	viability	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	0.20933825262572248	[832,782]	[522,757]	1	hSpCas9	negative selection	4545521
1455465	1455487	19	+	27760321	HL60	viability	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.7078983820878378	[384,347]	[203,160]	-6	hSpCas9	negative selection	4628982
1456878	1456900	19	-	27760321	HL60	viability	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-0.2919262392532028	[644,625]	[404,445]	-3	hSpCas9	negative selection	4628983
1456949	1456971	19	+	27760321	HL60	viability	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	0.0051155690398690945	[832,782]	[724,596]	0	hSpCas9	negative selection	4628984
1455465	1455487	19	+	27760321	HT1080	viability	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.20913403315838763	[347,271]	[113,98]	-1	hSpCas9	negative selection	4712445
1456878	1456900	19	-	27760321	HT1080	viability	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-0.6773423042167174	[625,488]	[146,129]	-3	hSpCas9	negative selection	4712446
1456949	1456971	19	+	27760321	HT1080	viability	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	-1.2045645921541284	[782,610]	[119,120]	-5	hSpCas9	negative selection	4712447
1455465	1455487	19	+	27760321	HT29	viability after 7 days	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.09422554910681427	[347,271]	[486,286,507]	1	hSpCas9	negative selection	4795908
1456878	1456900	19	-	27760321	HT29	viability after 7 days	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-0.8026755826557713	[625,488]	[590,385,284]	-8	hSpCas9	negative selection	4795909
1456949	1456971	19	+	27760321	HT29	viability after 7 days	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	0.2777690284943124	[782,610]	[1136,1014,1111]	4	hSpCas9	negative selection	4795910
1455465	1455487	19	+	27760321	HT29	viability after 25 days	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.13153030158470885	[347,271]	[287,360,322]	-1	hSpCas9	negative selection	4879371
1456878	1456900	19	-	27760321	HT29	viability after 25 days	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-1.2962363984874299	[625,488]	[315,227,226]	-7	hSpCas9	negative selection	4879372
1456949	1456971	19	+	27760321	HT29	viability after 25 days	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	0.1963157165346172	[782,610]	[1099,442,1212]	2	hSpCas9	negative selection	4879373
1455465	1455487	19	+	27760321	HT29	viability after 22 days	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.29647628173653956	[347,271]	[365,264,241]	-3	hSpCas9	negative selection	4962834
1456878	1456900	19	-	27760321	HT29	viability after 22 days	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-1.0959975674773477	[625,488]	[193,354,358]	-7	hSpCas9	negative selection	4962835
1456949	1456971	19	+	27760321	HT29	viability after 22 days	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	0.2929993326092446	[782,610]	[853,827,1285]	3	hSpCas9	negative selection	4962836
1455465	1455487	19	+	27760321	HT29	viability after 19 days	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.41530058533019537	[347,271]	[455,192,171]	-4	hSpCas9	negative selection	5046297
1456878	1456900	19	-	27760321	HT29	viability after 19 days	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-0.5261085756123763	[625,488]	[334,651,333]	-4	hSpCas9	negative selection	5046298
1456949	1456971	19	+	27760321	HT29	viability after 19 days	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	0.7710406969911645	[782,610]	[1171,876,1986]	7	hSpCas9	negative selection	5046299
1455465	1455487	19	+	27760321	HT29	viability after 16 days	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.14719267148500248	[347,271]	[466,164,325]	-1	hSpCas9	negative selection	5129760
1456878	1456900	19	-	27760321	HT29	viability after 16 days	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-0.6064596015349267	[625,488]	[585,243,419]	-5	hSpCas9	negative selection	5129761
1456949	1456971	19	+	27760321	HT29	viability after 16 days	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	0.18226438053236138	[782,610]	[1058,759,854]	2	hSpCas9	negative selection	5129762
1455465	1455487	19	+	27760321	HT29	viability after 13 days	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.22432100126422114	[347,271]	[471,430,360]	2	hSpCas9	negative selection	5213223
1456878	1456900	19	-	27760321	HT29	viability after 13 days	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-0.6034105707372772	[625,488]	[545,444,293]	-6	hSpCas9	negative selection	5213224
1456949	1456971	19	+	27760321	HT29	viability after 13 days	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	0.09704140587820564	[782,610]	[805,914,872]	1	hSpCas9	negative selection	5213225
1455465	1455487	19	+	27760321	HT29	viability after 10 days	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.12161080542806146	[347,271]	[411,283,368]	-2	hSpCas9	negative selection	5296686
1456878	1456900	19	-	27760321	HT29	viability after 10 days	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-0.7010401235699961	[625,488]	[495,607,190]	-7	hSpCas9	negative selection	5296687
1456949	1456971	19	+	27760321	HT29	viability after 10 days	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	-0.06592676558289601	[782,610]	[920,1112,475]	-1	hSpCas9	negative selection	5296688
1455465	1455487	19	+	27760321	MOLM13	viability	TTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.8866064593025776	[384,347]	[294,455]	6	hSpCas9	negative selection	5380149
1456878	1456900	19	-	27760321	MOLM13	viability	TGGTCGCGCGTCGCCAACATGG	APC2	ENSG00000115266	-1.5081839766657335	[644,625]	[101,146]	-7	hSpCas9	negative selection	5380150
1456949	1456971	19	+	27760321	MOLM13	viability	TGCGTGGCCATGCGCCGCTCGG	APC2	ENSG00000115266	-0.1509918474158215	[832,782]	[156,626]	-1	hSpCas9	negative selection	5380151
1446687	1446710	19	+	27661255	K562	viability	GCGGCTGCGGGGGCATCCTGCGG	APC2	ENSG00000115266	-1.4055960173215618	[368,331]	[120,92]	-9	dCas9-KRAB	negative selection	5462726
1450127	1450150	19	+	27661255	K562	viability	GTCTCGCCCAGCGCTAGGAGCGG	APC2	ENSG00000115266	0.026571221910620446	[334,404]	[292,305]	0	dCas9-KRAB	negative selection	5462727
1450552	1450575	19	+	27661255	K562	viability	GACCTCCCTGAGGTGATCGGAGG	APC2	ENSG00000115266	0.22864530437588082	[746,758]	[716,693]	7	dCas9-KRAB	negative selection	5462728
1450587	1450610	19	+	27661255	K562	viability	GGCCAGTGGTGTGTCTTCGGGGG	APC2	ENSG00000115266	0.03952598834651955	[929,1172]	[897,826]	1	dCas9-KRAB	negative selection	5462729
1446542	1446565	19	-	27661255	K562	viability	GTCGCAGCGGCGCACGAGAGGGG	APC2	ENSG00000115266	0.19185350010515928	[496,502]	[474,439]	6	dCas9-KRAB	negative selection	5462730
1450168	1450191	19	-	27661255	K562	viability	GGGCGGACAAAGCCCGGTCCGGG	APC2	ENSG00000115266	-0.07698855436547158	[1343,1195]	[993,937]	-3	dCas9-KRAB	negative selection	5462731
1450528	1450551	19	-	27661255	K562	viability	GGATGGTGAAGCCCGTGAGTGGG	APC2	ENSG00000115266	0.21234498711206518	[758,1122]	[914,821]	7	dCas9-KRAB	negative selection	5462732
1455464	1455487	19	+	27260156	BXPC3	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.36266890723745693	[39]	[67,54,33,55]	7	hSpCas9	negative selection	5528553
1455218	1455241	19	-	27260156	BXPC3	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-0.08692120769782363	[18]	[26,10,10,25]	-2	hSpCas9	negative selection	5528554
1453522	1453545	19	-	27260156	BXPC3	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.5387334923276221	[145]	[162,173,336,222]	9	hSpCas9	negative selection	5528555
1455443	1455466	19	-	27260156	BXPC3	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.1469474447478199	[354]	[295,391,437,545]	3	hSpCas9	negative selection	5592837
1455243	1455266	19	-	27260156	BXPC3	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	0.07737145090092673	[506]	[496,507,485,777]	1	hSpCas9	negative selection	5592838
1453518	1453541	19	+	27260156	BXPC3	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.09469601718179353	[431]	[361,298,454,610]	-2	hSpCas9	negative selection	5592839
1455464	1455487	19	+	27260156	A673	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.2625609468698267	[39]	[55,42,64,66]	6	hSpCas9	negative selection	5649804
1455218	1455241	19	-	27260156	A673	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	0.5591242300903261	[18]	[74,20,34,6]	9	hSpCas9	negative selection	5649805
1453522	1453545	19	-	27260156	A673	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.4571301247106947	[145]	[256,255,179,272]	8	hSpCas9	negative selection	5649806
1455443	1455466	19	-	27260156	A673	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.024824225797479837	[354]	[435,371,421,449]	0	hSpCas9	negative selection	5714088
1455243	1455266	19	-	27260156	A673	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	0.1462412998977462	[506]	[829,628,661,586]	3	hSpCas9	negative selection	5714089
1453518	1453541	19	+	27260156	A673	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.07106191712930321	[431]	[573,551,481,575]	1	hSpCas9	negative selection	5714090
1455464	1455487	19	+	27260156	A375	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	1.362260220982233	[39]	[133,154,94,102]	9	hSpCas9	negative selection	5771055
1455218	1455241	19	-	27260156	A375	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	0.6033853993774398	[18]	[0,34,67,30]	8	hSpCas9	negative selection	5771056
1453522	1453545	19	-	27260156	A375	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.5262959022526124	[145]	[218,237,238,279]	7	hSpCas9	negative selection	5771057
1455443	1455466	19	-	27260156	A375	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.391780915602198	[354]	[313,358,271,322]	-5	hSpCas9	negative selection	5835339
1455243	1455266	19	-	27260156	A375	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.03683669921374465	[506]	[380,815,642,506]	0	hSpCas9	negative selection	5835340
1453518	1453541	19	+	27260156	A375	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.049169895989345666	[431]	[444,481,683,352]	0	hSpCas9	negative selection	5835341
1455464	1455487	19	+	27260156	COLO741	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.6093105204285214	[39]	[29,152,48]	9	hSpCas9	negative selection	5892306
1455218	1455241	19	-	27260156	COLO741	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.0831566070759564	[18]	[3,21,7]	-9	hSpCas9	negative selection	5892307
1453522	1453545	19	-	27260156	COLO741	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.49497984254319105	[145]	[227,346,213]	8	hSpCas9	negative selection	5892308
1455443	1455466	19	-	27260156	COLO741	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.5803431358767467	[354]	[818,606,622]	9	hSpCas9	negative selection	5956590
1455243	1455266	19	-	27260156	COLO741	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	0.04986938414535716	[506]	[705,689,620]	1	hSpCas9	negative selection	5956591
1453518	1453541	19	+	27260156	COLO741	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.15369247572009836	[431]	[546,494,452]	-3	hSpCas9	negative selection	5956592
1455464	1455487	19	+	27260156	CAL120	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.4699564071460687	[39]	[67,32,104]	7	hSpCas9	negative selection	6013557
1455218	1455241	19	-	27260156	CAL120	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	0.8083080654950892	[18]	[121,10,3]	9	hSpCas9	negative selection	6013558
1453522	1453545	19	-	27260156	CAL120	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	-0.038010805971084416	[145]	[248,191,101]	0	hSpCas9	negative selection	6013559
1455443	1455466	19	-	27260156	CAL120	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.06197575699794855	[354]	[625,312,361]	-1	hSpCas9	negative selection	6077841
1455243	1455266	19	-	27260156	CAL120	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.014416295070195331	[506]	[814,558,529]	0	hSpCas9	negative selection	6077842
1453518	1453541	19	+	27260156	CAL120	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.07240636780400016	[431]	[411,447,655]	-1	hSpCas9	negative selection	6077843
1455464	1455487	19	+	27260156	CADOES1	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-1.188572639127373	[39]	[12,7,34,8]	-9	hSpCas9	negative selection	6134808
1455218	1455241	19	-	27260156	CADOES1	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	0.45282807505539946	[18]	[6,29,55,2]	7	hSpCas9	negative selection	6134809
1453522	1453545	19	-	27260156	CADOES1	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.38112689849891557	[145]	[144,271,130,158]	6	hSpCas9	negative selection	6134810
1455443	1455466	19	-	27260156	CADOES1	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.16675509865028576	[354]	[234,288,374,276]	-3	hSpCas9	negative selection	6199092
1455243	1455266	19	-	27260156	CADOES1	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.1627428162606149	[506]	[401,417,417,447]	-3	hSpCas9	negative selection	6199093
1453518	1453541	19	+	27260156	CADOES1	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.30955957734389467	[431]	[583,699,363,337]	5	hSpCas9	negative selection	6199094
1455464	1455487	19	+	27260156	EWS502	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.036220632273653575	[39]	[30,43,55,34]	0	hSpCas9	negative selection	6256059
1455218	1455241	19	-	27260156	EWS502	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.1994054253702933	[18]	[18,0,5,7]	-9	hSpCas9	negative selection	6256060
1453522	1453545	19	-	27260156	EWS502	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.4078279227511612	[145]	[270,226,163,143]	7	hSpCas9	negative selection	6256061
1455443	1455466	19	-	27260156	EWS502	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.10279346675871942	[354]	[506,265,232,377]	-2	hSpCas9	negative selection	6320343
1455243	1455266	19	-	27260156	EWS502	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.04425515699322302	[506]	[520,475,541,545]	-1	hSpCas9	negative selection	6320344
1453518	1453541	19	+	27260156	EWS502	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.030579349509772938	[431]	[315,574,578,408]	0	hSpCas9	negative selection	6320345
1455464	1455487	19	+	27260156	EW8	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.07504805930760661	[39]	[82,26,17,2]	-1	hSpCas9	negative selection	6377310
1455218	1455241	19	-	27260156	EW8	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-0.025887500564174992	[18]	[5,0,10,41]	0	hSpCas9	negative selection	6377311
1453522	1453545	19	-	27260156	EW8	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.26647749802666953	[145]	[73,156,161,164]	5	hSpCas9	negative selection	6377312
1455443	1455466	19	-	27260156	EW8	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.0924849753691423	[354]	[163,368,253,282]	-2	hSpCas9	negative selection	6441594
1455243	1455266	19	-	27260156	EW8	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.29317826747210496	[506]	[248,428,288,371]	-5	hSpCas9	negative selection	6441595
1453518	1453541	19	+	27260156	EW8	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.2034910680478414	[431]	[350,382,494,360]	4	hSpCas9	negative selection	6441596
1455464	1455487	19	+	27260156	CORL105	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.03151353608782648	[39]	[72,19,28,59]	0	hSpCas9	negative selection	6498561
1455218	1455241	19	-	27260156	CORL105	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.0807164350789797	[18]	[32,2,3,1]	-9	hSpCas9	negative selection	6498562
1453522	1453545	19	-	27260156	CORL105	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.4462785570449539	[145]	[159,308,204,248]	7	hSpCas9	negative selection	6498563
1455443	1455466	19	-	27260156	CORL105	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.017400837379021816	[354]	[408,280,494,510]	0	hSpCas9	negative selection	6562845
1455243	1455266	19	-	27260156	CORL105	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.2027639929069736	[506]	[597,295,657,539]	-4	hSpCas9	negative selection	6562846
1453518	1453541	19	+	27260156	CORL105	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.03710941665976229	[431]	[499,510,502,458]	0	hSpCas9	negative selection	6562847
1455464	1455487	19	+	27260156	HS294T	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-1.0133857877619938	[39]	[6,4,9,8]	-9	hSpCas9	negative selection	6619812
1455218	1455241	19	-	27260156	HS294T	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.126343571075024	[18]	[2,5,2,0]	-9	hSpCas9	negative selection	6619813
1453522	1453545	19	-	27260156	HS294T	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.17764901063629002	[145]	[24,53,132,43]	2	hSpCas9	negative selection	6619814
1455443	1455466	19	-	27260156	HS294T	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.07807523132200594	[354]	[63,226,123,173]	1	hSpCas9	negative selection	6684096
1455243	1455266	19	-	27260156	HS294T	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.6253285121836265	[506]	[118,78,146,172]	-7	hSpCas9	negative selection	6684097
1453518	1453541	19	+	27260156	HS294T	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.09845796812930906	[431]	[181,121,182,130]	-1	hSpCas9	negative selection	6684098
1455464	1455487	19	+	27260156	HCC44	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.5486667913349246	[39]	[53,60,74,74]	8	hSpCas9	negative selection	6741063
1455218	1455241	19	-	27260156	HCC44	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.484057958715706	[18]	[6,9,10,2]	-9	hSpCas9	negative selection	6741064
1453522	1453545	19	-	27260156	HCC44	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.14120400931138466	[145]	[174,142,200,214]	2	hSpCas9	negative selection	6741065
1455443	1455466	19	-	27260156	HCC44	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.43398350385682033	[354]	[469,555,601,538]	7	hSpCas9	negative selection	6805347
1455243	1455266	19	-	27260156	HCC44	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	0.19257846919914984	[506]	[662,668,607,665]	3	hSpCas9	negative selection	6805348
1453518	1453541	19	+	27260156	HCC44	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.3873431087825989	[431]	[826,415,676,684]	6	hSpCas9	negative selection	6805349
1455464	1455487	19	+	27260156	G402	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-1.4144175750734833	[39]	[0,6,0,58]	-9	hSpCas9	negative selection	6862314
1455218	1455241	19	-	27260156	G402	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-0.3708683453183683	[18]	[51,10,12,0]	-5	hSpCas9	negative selection	6862315
1453522	1453545	19	-	27260156	G402	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.5432421224399164	[145]	[55,218,329,393]	6	hSpCas9	negative selection	6862316
1455443	1455466	19	-	27260156	G402	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.3510166984434124	[354]	[297,583,326,164]	-4	hSpCas9	negative selection	6926598
1455243	1455266	19	-	27260156	G402	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.47059443003289575	[506]	[638,677,202,311]	-5	hSpCas9	negative selection	6926599
1453518	1453541	19	+	27260156	G402	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.5319555222936053	[431]	[224,515,307,394]	-6	hSpCas9	negative selection	6926600
1455464	1455487	19	+	27260156	L33	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.38667394431356295	[39]	[19,12,12,49]	-7	hSpCas9	negative selection	6983565
1455218	1455241	19	-	27260156	L33	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	0.4933534589106925	[18]	[0,16,23,26]	8	hSpCas9	negative selection	6983566
1453522	1453545	19	-	27260156	L33	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.0767054089469128	[145]	[118,47,141,154]	1	hSpCas9	negative selection	6983567
1455443	1455466	19	-	27260156	L33	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.025405965948566145	[354]	[498,147,187,232]	0	hSpCas9	negative selection	7047849
1455243	1455266	19	-	27260156	L33	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.18484219394656445	[506]	[472,180,292,402]	-4	hSpCas9	negative selection	7047850
1453518	1453541	19	+	27260156	L33	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.1602664450964859	[431]	[541,176,266,529]	3	hSpCas9	negative selection	7047851
1455464	1455487	19	+	27260156	K562	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-1.7189713727163003	[39]	[29,0,0,11]	-9	hSpCas9	negative selection	7104816
1455218	1455241	19	-	27260156	K562	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	0.9479527416830513	[18]	[97,16,0,19]	9	hSpCas9	negative selection	7104817
1453522	1453545	19	-	27260156	K562	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	-0.8262338934506912	[145]	[143,43,60,49]	-7	hSpCas9	negative selection	7104818
1455443	1455466	19	-	27260156	K562	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.5636281659225764	[354]	[193,249,231,179]	-6	hSpCas9	negative selection	7169100
1455243	1455266	19	-	27260156	K562	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.5229247832355073	[506]	[358,364,119,402]	-6	hSpCas9	negative selection	7169101
1453518	1453541	19	+	27260156	K562	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.08103717178759605	[431]	[415,350,256,420]	-1	hSpCas9	negative selection	7169102
1455464	1455487	19	+	27260156	HT29	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.6107485563068762	[39]	[110,65,77,46]	9	hSpCas9	negative selection	7226067
1455218	1455241	19	-	27260156	HT29	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-0.4913824845288204	[18]	[2,30,25,6]	-7	hSpCas9	negative selection	7226068
1453522	1453545	19	-	27260156	HT29	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.06174623418987868	[145]	[216,208,158,161]	1	hSpCas9	negative selection	7226069
1455443	1455466	19	-	27260156	HT29	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.21470685694482178	[354]	[408,403,364,318]	-4	hSpCas9	negative selection	7290351
1455243	1455266	19	-	27260156	HT29	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.04321809391601064	[506]	[778,570,534,523]	-1	hSpCas9	negative selection	7290352
1453518	1453541	19	+	27260156	HT29	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.10958521455158252	[431]	[446,620,589,595]	2	hSpCas9	negative selection	7290353
1455464	1455487	19	+	27260156	MHHES1	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.5046001810590188	[39]	[55,9,56,112]	8	hSpCas9	negative selection	7347318
1455218	1455241	19	-	27260156	MHHES1	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	0.3074718849864926	[18]	[8,45,32,18]	5	hSpCas9	negative selection	7347319
1453522	1453545	19	-	27260156	MHHES1	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.07676190615950507	[145]	[186,175,157,170]	1	hSpCas9	negative selection	7347320
1455443	1455466	19	-	27260156	MHHES1	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.24235186828539318	[354]	[402,392,309,267]	-4	hSpCas9	negative selection	7411602
1455243	1455266	19	-	27260156	MHHES1	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.12906268212638922	[506]	[709,542,476,399]	-2	hSpCas9	negative selection	7411603
1453518	1453541	19	+	27260156	MHHES1	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.24098968548424804	[431]	[483,378,441,351]	-4	hSpCas9	negative selection	7411604
1455464	1455487	19	+	27260156	MEWO	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.3345772196452441	[39]	[23,13,49]	-6	hSpCas9	negative selection	7468569
1455218	1455241	19	-	27260156	MEWO	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.5998577596896304	[18]	[7,6,2]	-9	hSpCas9	negative selection	7468570
1453522	1453545	19	-	27260156	MEWO	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.2512455102330451	[145]	[185,209,95]	5	hSpCas9	negative selection	7468571
1455443	1455466	19	-	27260156	MEWO	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.05142967547705357	[354]	[420,295,263]	-1	hSpCas9	negative selection	7532853
1455243	1455266	19	-	27260156	MEWO	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.014896861796963659	[506]	[574,410,442]	0	hSpCas9	negative selection	7532854
1453518	1453541	19	+	27260156	MEWO	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.30514756745614463	[431]	[478,263,267]	-6	hSpCas9	negative selection	7532855
1455464	1455487	19	+	27260156	LNCAPCLONEFGC	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.09168869957460268	[39]	[9,79,10,28]	-1	hSpCas9	negative selection	7589820
1455218	1455241	19	-	27260156	LNCAPCLONEFGC	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-0.3087375550071805	[18]	[14,8,7,22]	-5	hSpCas9	negative selection	7589821
1453522	1453545	19	-	27260156	LNCAPCLONEFGC	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.7571825772005779	[145]	[254,201,143,281]	9	hSpCas9	negative selection	7589822
1455443	1455466	19	-	27260156	LNCAPCLONEFGC	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.4660304401612954	[354]	[199,219,255,259]	-6	hSpCas9	negative selection	7654104
1455243	1455266	19	-	27260156	LNCAPCLONEFGC	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.4306214249746608	[506]	[379,349,236,378]	-6	hSpCas9	negative selection	7654105
1453518	1453541	19	+	27260156	LNCAPCLONEFGC	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.1596998123579379	[431]	[365,447,585,370]	2	hSpCas9	negative selection	7654106
1455464	1455487	19	+	27260156	PANC0327	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-1.3925391575154675	[39]	[3,23,12,10]	-9	hSpCas9	negative selection	7711071
1455218	1455241	19	-	27260156	PANC0327	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.0962659437859017	[18]	[3,1,3,21]	-8	hSpCas9	negative selection	7711072
1453522	1453545	19	-	27260156	PANC0327	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	-0.6422143679358958	[145]	[121,71,80,61]	-7	hSpCas9	negative selection	7711073
1455443	1455466	19	-	27260156	PANC0327	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.2752446072196751	[354]	[956,192,310,136]	4	hSpCas9	negative selection	7775355
1455243	1455266	19	-	27260156	PANC0327	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.5425607634836291	[506]	[271,134,306,541]	-6	hSpCas9	negative selection	7775356
1453518	1453541	19	+	27260156	PANC0327	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.08692057975355379	[431]	[231,636,330,198]	-1	hSpCas9	negative selection	7775357
1455464	1455487	19	+	27260156	NCIH2009	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-1.4526293416067286	[39]	[19,27,12]	-9	hSpCas9	negative selection	7832322
1455218	1455241	19	-	27260156	NCIH2009	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.3915375655483464	[18]	[12,4,12]	-9	hSpCas9	negative selection	7832323
1453522	1453545	19	-	27260156	NCIH2009	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.7600788031901035	[145]	[568,289,221]	9	hSpCas9	negative selection	7832324
1455443	1455466	19	-	27260156	NCIH2009	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.15100444059039758	[354]	[576,738,336]	2	hSpCas9	negative selection	7896606
1455243	1455266	19	-	27260156	NCIH2009	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.287149024624453	[506]	[744,418,611]	-4	hSpCas9	negative selection	7896607
1453518	1453541	19	+	27260156	NCIH2009	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.1815590570334382	[431]	[814,528,736]	2	hSpCas9	negative selection	7896608
1455464	1455487	19	+	27260156	NCIH1373	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.5222877303240523	[39]	[40,58,3,4]	-5	hSpCas9	negative selection	7953573
1455218	1455241	19	-	27260156	NCIH1373	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-0.3448053328665157	[18]	[37,8,15,1]	-3	hSpCas9	negative selection	7953574
1453522	1453545	19	-	27260156	NCIH1373	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	-0.0763930858509041	[145]	[291,123,63,43]	0	hSpCas9	negative selection	7953575
1455443	1455466	19	-	27260156	NCIH1373	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.30197125114552253	[354]	[357,654,470,113]	3	hSpCas9	negative selection	8017857
1455243	1455266	19	-	27260156	NCIH1373	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.10542488528765973	[506]	[1009,393,324,123]	-1	hSpCas9	negative selection	8017858
1453518	1453541	19	+	27260156	NCIH1373	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.08674504658386567	[431]	[843,318,496,121]	0	hSpCas9	negative selection	8017859
1455464	1455487	19	+	27260156	PATU8902	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	1.565268616086851	[39]	[261,7,201,175]	9	hSpCas9	negative selection	8074824
1455218	1455241	19	-	27260156	PATU8902	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.321544700880363	[18]	[0,31,0,10]	-8	hSpCas9	negative selection	8074825
1453522	1453545	19	-	27260156	PATU8902	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.5276581956352135	[145]	[240,490,66,449]	5	hSpCas9	negative selection	8074826
1455443	1455466	19	-	27260156	PATU8902	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.5411222532532065	[354]	[214,430,155,639]	-5	hSpCas9	negative selection	8139108
1455243	1455266	19	-	27260156	PATU8902	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.4065631544870396	[506]	[641,406,439,676]	-4	hSpCas9	negative selection	8139109
1453518	1453541	19	+	27260156	PATU8902	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.1293728661257137	[431]	[633,371,826,761]	1	hSpCas9	negative selection	8139110
1455464	1455487	19	+	27260156	PANC1	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.17978823103200536	[39]	[26,16,34,66]	3	hSpCas9	negative selection	8196075
1455218	1455241	19	-	27260156	PANC1	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.2376487106374272	[18]	[15,6,1,2]	-9	hSpCas9	negative selection	8196076
1453522	1453545	19	-	27260156	PANC1	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.39715185170511846	[145]	[163,223,165,122]	6	hSpCas9	negative selection	8196077
1455443	1455466	19	-	27260156	PANC1	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.0643869955303022	[354]	[461,324,256,144]	-1	hSpCas9	negative selection	8260359
1455243	1455266	19	-	27260156	PANC1	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.0015168228860118482	[506]	[308,663,439,378]	0	hSpCas9	negative selection	8260360
1453518	1453541	19	+	27260156	PANC1	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.10776791194588208	[431]	[346,530,426,327]	1	hSpCas9	negative selection	8260361
1455464	1455487	19	+	27260156	PANC0813	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.778683004816322	[39]	[60,23,225,13]	9	hSpCas9	negative selection	8317326
1455218	1455241	19	-	27260156	PANC0813	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-0.9299157259527906	[18]	[6,17,2,17]	-8	hSpCas9	negative selection	8317327
1453522	1453545	19	-	27260156	PANC0813	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.42415934362792096	[145]	[254,180,212,270]	6	hSpCas9	negative selection	8317328
1455443	1455466	19	-	27260156	PANC0813	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.24626966640137643	[354]	[345,361,257,433]	-4	hSpCas9	negative selection	8381610
1455243	1455266	19	-	27260156	PANC0813	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.12767225896588025	[506]	[699,585,448,462]	-2	hSpCas9	negative selection	8381611
1453518	1453541	19	+	27260156	PANC0813	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.13678937704385122	[431]	[605,651,513,467]	2	hSpCas9	negative selection	8381612
1455464	1455487	19	+	27260156	RDES	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.22062710624849746	[39]	[23,89,10,26]	-4	hSpCas9	negative selection	8438577
1455218	1455241	19	-	27260156	RDES	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.7873420946203282	[18]	[6,6,2,7]	-9	hSpCas9	negative selection	8438578
1453522	1453545	19	-	27260156	RDES	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.6686185752142646	[145]	[328,231,239,240]	9	hSpCas9	negative selection	8438579
1455443	1455466	19	-	27260156	RDES	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.2743677425149059	[354]	[382,601,413,584]	4	hSpCas9	negative selection	8502861
1455243	1455266	19	-	27260156	RDES	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	0.1096553182059028	[506]	[498,610,790,632]	1	hSpCas9	negative selection	8502862
1453518	1453541	19	+	27260156	RDES	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.18891603534729556	[431]	[541,458,592,687]	3	hSpCas9	negative selection	8502863
1455464	1455487	19	+	27260156	PC3	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.09252620062198913	[39]	[30,24,33,57]	-2	hSpCas9	negative selection	8559828
1455218	1455241	19	-	27260156	PC3	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.745955657816742	[18]	[7,0,0,8]	-9	hSpCas9	negative selection	8559829
1453522	1453545	19	-	27260156	PC3	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.8392679645584241	[145]	[295,257,330,117]	9	hSpCas9	negative selection	8559830
1455443	1455466	19	-	27260156	PC3	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.3184327839707623	[354]	[306,440,777,378]	6	hSpCas9	negative selection	8624112
1455243	1455266	19	-	27260156	PC3	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.061405951589888465	[506]	[230,437,990,554]	-1	hSpCas9	negative selection	8624113
1453518	1453541	19	+	27260156	PC3	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.1141880886481919	[431]	[308,360,525,440]	-3	hSpCas9	negative selection	8624114
1455464	1455487	19	+	27260156	PATU8988T	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.6458646108890669	[39]	[2,59,16,21]	-7	hSpCas9	negative selection	8681079
1455218	1455241	19	-	27260156	PATU8988T	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-0.701471623099974	[18]	[0,38,5,0]	-8	hSpCas9	negative selection	8681080
1453522	1453545	19	-	27260156	PATU8988T	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	-0.0018016062189345483	[145]	[46,101,181,235]	0	hSpCas9	negative selection	8681081
1455443	1455466	19	-	27260156	PATU8988T	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.6528132237534434	[354]	[209,176,186,301]	-7	hSpCas9	negative selection	8745363
1455243	1455266	19	-	27260156	PATU8988T	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.706564696653176	[506]	[292,443,177,300]	-8	hSpCas9	negative selection	8745364
1453518	1453541	19	+	27260156	PATU8988T	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.4247713034000283	[431]	[338,236,362,295]	-6	hSpCas9	negative selection	8745365
1455464	1455487	19	+	27260156	T47D	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.02241264229569806	[39]	[31,33,54,69]	0	hSpCas9	negative selection	8802330
1455218	1455241	19	-	27260156	T47D	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-1.1080176060730276	[18]	[16,10,5,6]	-9	hSpCas9	negative selection	8802331
1453522	1453545	19	-	27260156	T47D	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.1715511891358621	[145]	[171,191,225,174]	3	hSpCas9	negative selection	8802332
1455443	1455466	19	-	27260156	T47D	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.16553300887088485	[354]	[402,537,460,445]	3	hSpCas9	negative selection	8866614
1455243	1455266	19	-	27260156	T47D	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	0.12534011356291513	[506]	[628,632,595,722]	2	hSpCas9	negative selection	8866615
1453518	1453541	19	+	27260156	T47D	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.12575607276607226	[431]	[499,387,456,507]	-3	hSpCas9	negative selection	8866616
1455464	1455487	19	+	27260156	SU8686	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	0.00017210524865474142	[39]	[32,26,32,72]	0	hSpCas9	negative selection	8923581
1455218	1455241	19	-	27260156	SU8686	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-0.6419169615637896	[18]	[8,1,28,9]	-7	hSpCas9	negative selection	8923582
1453522	1453545	19	-	27260156	SU8686	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.1032976561545611	[145]	[114,143,198,172]	1	hSpCas9	negative selection	8923583
1455443	1455466	19	-	27260156	SU8686	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.09039868511040505	[354]	[277,334,250,483]	-2	hSpCas9	negative selection	8987865
1455243	1455266	19	-	27260156	SU8686	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.15978205219012653	[506]	[378,376,541,531]	-3	hSpCas9	negative selection	8987866
1453518	1453541	19	+	27260156	SU8686	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.08043170426584025	[431]	[314,372,570,371]	-1	hSpCas9	negative selection	8987867
1455464	1455487	19	+	27260156	SKES1	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.28041789767141756	[39]	[12,46,47,22]	-6	hSpCas9	negative selection	9044832
1455218	1455241	19	-	27260156	SKES1	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-0.38485801417135157	[18]	[20,4,20,10]	-7	hSpCas9	negative selection	9044833
1453522	1453545	19	-	27260156	SKES1	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.28246147792051257	[145]	[210,210,176,122]	6	hSpCas9	negative selection	9044834
1455443	1455466	19	-	27260156	SKES1	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.14726150147863998	[354]	[615,325,395,264]	3	hSpCas9	negative selection	9109116
1455243	1455266	19	-	27260156	SKES1	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	0.1449154957909609	[506]	[582,609,528,522]	3	hSpCas9	negative selection	9109117
1453518	1453541	19	+	27260156	SKES1	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.22491618501323168	[431]	[445,513,621,427]	5	hSpCas9	negative selection	9109118
1455464	1455487	19	+	27260156	TOV112D	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.7735133148033029	[39]	[0,64,10,24]	-9	hSpCas9	negative selection	9166083
1455218	1455241	19	-	27260156	TOV112D	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-2.5741578498690414	[18]	[0,0,4,4]	-9	hSpCas9	negative selection	9166084
1453522	1453545	19	-	27260156	TOV112D	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.7878946124037282	[145]	[236,463,207,153]	9	hSpCas9	negative selection	9166085
1455443	1455466	19	-	27260156	TOV112D	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.3147015925837061	[354]	[393,844,355,272]	6	hSpCas9	negative selection	9230367
1455243	1455266	19	-	27260156	TOV112D	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	-0.13316041216930535	[506]	[513,576,378,414]	-3	hSpCas9	negative selection	9230368
1453518	1453541	19	+	27260156	TOV112D	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	0.22860362100729625	[431]	[566,651,350,497]	4	hSpCas9	negative selection	9230369
1455464	1455487	19	+	27260156	TC71	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.024872195497332328	[39]	[11,50,48,57]	0	hSpCas9	negative selection	9287334
1455218	1455241	19	-	27260156	TC71	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-0.6816176043914215	[18]	[11,9,12,15]	-9	hSpCas9	negative selection	9287335
1453522	1453545	19	-	27260156	TC71	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.2927611970231905	[145]	[290,130,210,126]	7	hSpCas9	negative selection	9287336
1455443	1455466	19	-	27260156	TC71	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	0.05462222805091238	[354]	[398,361,421,396]	1	hSpCas9	negative selection	9351618
1455243	1455266	19	-	27260156	TC71	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	0.1294697210666197	[506]	[553,734,597,484]	3	hSpCas9	negative selection	9351619
1453518	1453541	19	+	27260156	TC71	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.1340622052809628	[431]	[457,356,490,375]	-4	hSpCas9	negative selection	9351620
1455464	1455487	19	+	27260156	TC32	viability	CTTCGGCACCTCGGACGAGATGG	APC2	ENSG00000115266	-0.877429629354828	[39]	[22,17,3,33]	-9	hSpCas9	negative selection	9408585
1455218	1455241	19	-	27260156	TC32	viability	GCTCGTCCAGGCGCTTGGACAGG	APC2	ENSG00000115266	-2.094143906788097	[18]	[0,0,6,9]	-9	hSpCas9	negative selection	9408586
1453522	1453545	19	-	27260156	TC32	viability	AGGGCCCGGAGCCGTGTACTGGG	APC2	ENSG00000115266	0.12866948889450414	[145]	[89,118,293,131]	2	hSpCas9	negative selection	9408587
1455443	1455466	19	-	27260156	TC32	viability	AGCGCTCCTCCATCAGCGAGCGG	APC2	ENSG00000115266	-0.007505280131120506	[354]	[349,256,398,338]	0	hSpCas9	negative selection	9472869
1455243	1455266	19	-	27260156	TC32	viability	CGGCTCACCGTCTCCACGTGCGG	APC2	ENSG00000115266	0.06540332066506724	[506]	[500,312,580,663]	1	hSpCas9	negative selection	9472870
1453518	1453541	19	+	27260156	TC32	viability	GCAGCCCAGTACACGGCTCCGGG	APC2	ENSG00000115266	-0.1565964278873947	[431]	[343,253,492,413]	-3	hSpCas9	negative selection	9472871
1453070	1453093	19	-	27869803	HPAFII	viability after 27 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-0.80486965866801	[28]	[17,0,NaN]	-5	hSpCas9	negative selection	9565942
1453420	1453443	19	+	27869803	HPAFII	viability after 27 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.20417199952255216	[700]	[344,298,NaN]	-1	hSpCas9	negative selection	9565943
1455236	1455259	19	+	27869803	HPAFII	viability after 27 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	0.014822851735188547	[279]	[193,110,NaN]	0	hSpCas9	negative selection	9565945
1455479	1455502	19	+	27869803	HPAFII	viability after 27 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.5349637761289295	[231]	[129,45,NaN]	-4	hSpCas9	negative selection	9565947
1456307	1456330	19	-	27869803	HPAFII	viability after 27 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	-0.16239308986032497	[829]	[390,388,NaN]	-1	hSpCas9	negative selection	9565952
1457048	1457071	19	-	27869803	HPAFII	viability after 27 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	1.968414171884281	[75]	[295,39,NaN]	9	hSpCas9	negative selection	9565953
1453070	1453093	19	-	27869803	HPAFII	viability after 15 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-1.711347171874527	[28]	[19,2,NaN]	-9	hSpCas9	negative selection	9648391
1453420	1453443	19	+	27869803	HPAFII	viability after 15 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	0.15849883595623915	[700]	[1253,583,NaN]	1	hSpCas9	negative selection	9648392
1455236	1455259	19	+	27869803	HPAFII	viability after 15 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.3874237390613881	[279]	[279,198,NaN]	-4	hSpCas9	negative selection	9648394
1455479	1455502	19	+	27869803	HPAFII	viability after 15 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.47869496225246144	[231]	[329,84,NaN]	-5	hSpCas9	negative selection	9648396
1456307	1456330	19	-	27869803	HPAFII	viability after 15 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	-0.07190963230461933	[829]	[1061,715,NaN]	0	hSpCas9	negative selection	9648401
1457048	1457071	19	-	27869803	HPAFII	viability after 15 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	2.2592924842980606	[75]	[871,91,NaN]	9	hSpCas9	negative selection	9648402
1453070	1453093	19	-	27869803	ASPC1	viability after 36 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-1.9351484742836185	[66]	[0,16,0]	-9	hSpCas9	negative selection	9730840
1453420	1453443	19	+	27869803	ASPC1	viability after 36 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	0.5089973586496519	[1765]	[1015,1051,631]	5	hSpCas9	negative selection	9730841
1455236	1455259	19	+	27869803	ASPC1	viability after 36 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	1.7620260134969243	[578]	[424,507,1001]	9	hSpCas9	negative selection	9730843
1455479	1455502	19	+	27869803	ASPC1	viability after 36 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.48516583628586785	[410]	[61,32,184]	-5	hSpCas9	negative selection	9730845
1456307	1456330	19	-	27869803	ASPC1	viability after 36 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	-0.1377310331774746	[2191]	[1021,706,449]	-1	hSpCas9	negative selection	9730850
1457048	1457071	19	-	27869803	ASPC1	viability after 36 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	-0.35983450547173956	[221]	[169,0,29]	-4	hSpCas9	negative selection	9730851
1453070	1453093	19	-	27869803	PATU8988S	viability after 35 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-2.2191196129910273	[74]	[0,11,NaN]	-9	hSpCas9	negative selection	9813289
1453420	1453443	19	+	27869803	PATU8988S	viability after 35 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	0.7336229017325935	[1625]	[1275,900,NaN]	7	hSpCas9	negative selection	9813290
1455236	1455259	19	+	27869803	PATU8988S	viability after 35 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	0.07379877176995223	[597]	[246,259,NaN]	0	hSpCas9	negative selection	9813292
1455479	1455502	19	+	27869803	PATU8988S	viability after 35 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.006634630627856256	[513]	[233,177,NaN]	0	hSpCas9	negative selection	9813294
1456307	1456330	19	-	27869803	PATU8988S	viability after 35 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.7865233539925496	[1975]	[1041,1704,NaN]	8	hSpCas9	negative selection	9813299
1457048	1457071	19	-	27869803	PATU8988S	viability after 35 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	-0.05274583151730727	[186]	[120,23,NaN]	0	hSpCas9	negative selection	9813300
1453070	1453093	19	-	27869803	PATU8988S	viability after 31 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-1.895416432476519	[74]	[0,16,NaN]	-9	hSpCas9	negative selection	9895738
1453420	1453443	19	+	27869803	PATU8988S	viability after 31 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	0.6177373861310715	[1625]	[1004,981,NaN]	7	hSpCas9	negative selection	9895739
1455236	1455259	19	+	27869803	PATU8988S	viability after 31 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	0.20128539071822674	[597]	[223,337,NaN]	2	hSpCas9	negative selection	9895741
1455479	1455502	19	+	27869803	PATU8988S	viability after 31 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	0.06420397203027878	[513]	[219,206,NaN]	0	hSpCas9	negative selection	9895743
1456307	1456330	19	-	27869803	PATU8988S	viability after 31 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	0.6802958921617506	[1975]	[933,1680,NaN]	7	hSpCas9	negative selection	9895748
1457048	1457071	19	-	27869803	PATU8988S	viability after 31 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	-1.3586159078404199	[186]	[14,46,NaN]	-8	hSpCas9	negative selection	9895749
1453070	1453093	19	-	27869803	HPAFII	viability after 35 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-1.8131263554425248	[28]	[6,0,NaN]	-7	hSpCas9	negative selection	9978187
1453420	1453443	19	+	27869803	HPAFII	viability after 35 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.0037698439475721823	[700]	[376,327,NaN]	0	hSpCas9	negative selection	9978188
1455236	1455259	19	+	27869803	HPAFII	viability after 35 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.059102823873122906	[279]	[136,134,NaN]	0	hSpCas9	negative selection	9978190
1455479	1455502	19	+	27869803	HPAFII	viability after 35 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-1.2338621599448003	[231]	[40,59,NaN]	-6	hSpCas9	negative selection	9978192
1456307	1456330	19	-	27869803	HPAFII	viability after 35 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	-0.6816518673179124	[829]	[189,342,NaN]	-4	hSpCas9	negative selection	9978197
1457048	1457071	19	-	27869803	HPAFII	viability after 35 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	2.8287134083570447	[75]	[484,34,NaN]	9	hSpCas9	negative selection	9978198
1453070	1453093	19	-	27869803	HPAFII	viability after 31 days	CCCTTAGCTCCTGCCTCAGGTGG	APC2	ENSG00000115266	-0.9714984589927518	[28]	[14,0,NaN]	-6	hSpCas9	negative selection	10060636
1453420	1453443	19	+	27869803	HPAFII	viability after 31 days	CGCCCATCCAGCCCTACAGATGG	APC2	ENSG00000115266	-0.03523215811643987	[700]	[303,470,NaN]	0	hSpCas9	negative selection	10060637
1455236	1455259	19	+	27869803	HPAFII	viability after 31 days	CGAGCTGCCGCACGTGGAGACGG	APC2	ENSG00000115266	-0.16501035688849922	[279]	[165,111,NaN]	-1	hSpCas9	negative selection	10060639
1455479	1455502	19	+	27869803	HPAFII	viability after 31 days	CGAGATGGTGCAGCGGGCACAGG	APC2	ENSG00000115266	-0.8444164585561752	[231]	[83,59,NaN]	-5	hSpCas9	negative selection	10060641
1456307	1456330	19	-	27869803	HPAFII	viability after 31 days	CACCGACTTCACCGCCAGCAAGG	APC2	ENSG00000115266	-0.40314043024939306	[829]	[301,406,NaN]	-3	hSpCas9	negative selection	10060646
1457048	1457071	19	-	27869803	HPAFII	viability after 31 days	ATGCGTGCGTCCTTGGCGCCCGG	APC2	ENSG00000115266	2.2581720835642	[75]	[338,56,NaN]	9	hSpCas9	negative selection	10060647
1453028	1453051	19	+	28162770	P31FUJ	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-1.905227546385874	[152]	[47]	-8	hSpCas9	negative selection	10111889
1453297	1453320	19	+	28162770	P31FUJ	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-0.8608334270274205	[33]	[21]	-6	hSpCas9	negative selection	10111890
1453315	1453338	19	+	28162770	P31FUJ	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	0.20284557453975144	[138]	[187]	2	hSpCas9	negative selection	10111891
1455164	1455187	19	+	28162770	P31FUJ	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-1.6602234281490549	[77]	[28]	-8	hSpCas9	negative selection	10111892
1457076	1457099	19	-	28162770	P31FUJ	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	0.311926371504102	[302]	[441]	3	hSpCas9	negative selection	10111893
1461087	1461110	19	+	28162770	P31FUJ	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	-0.39077789725505596	[510]	[457]	-4	hSpCas9	negative selection	10111894
1453028	1453051	19	+	28162770	TF1	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	NaN	[NaN]	[9]	1	hSpCas9	negative selection	10281255
1453297	1453320	19	+	28162770	TF1	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10281256
1453315	1453338	19	+	28162770	TF1	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10281257
1455164	1455187	19	+	28162770	TF1	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10281258
1457076	1457099	19	-	28162770	TF1	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	NaN	[NaN]	[332]	1	hSpCas9	negative selection	10281259
1461087	1461110	19	+	28162770	TF1	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	NaN	[NaN]	[355]	1	hSpCas9	negative selection	10281260
1453028	1453051	19	+	28162770	SKM1	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-1.2984397419649927	[31]	[22]	-7	hSpCas9	negative selection	10450621
1453297	1453320	19	+	28162770	SKM1	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-2.4069641987431614	[11]	[3]	-8	hSpCas9	negative selection	10450622
1453315	1453338	19	+	28162770	SKM1	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	-0.1939704754089634	[43]	[67]	-2	hSpCas9	negative selection	10450623
1455164	1455187	19	+	28162770	SKM1	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-2.3663222142458156	[34]	[11]	-8	hSpCas9	negative selection	10450624
1457076	1457099	19	-	28162770	SKM1	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	-0.2814333166593027	[54]	[79]	-2	hSpCas9	negative selection	10450625
1461087	1461110	19	+	28162770	SKM1	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	0.45432953042524604	[89]	[217]	4	hSpCas9	negative selection	10450626
1453028	1453051	19	+	28162770	SKM1	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-1.2984397419649927	[31]	[22]	-7	hSpCas9	negative selection	10619987
1453297	1453320	19	+	28162770	SKM1	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-2.4069641987431614	[11]	[3]	-8	hSpCas9	negative selection	10619988
1453315	1453338	19	+	28162770	SKM1	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	-0.1939704754089634	[43]	[67]	-2	hSpCas9	negative selection	10619989
1455164	1455187	19	+	28162770	SKM1	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-2.3663222142458156	[34]	[11]	-8	hSpCas9	negative selection	10619990
1457076	1457099	19	-	28162770	SKM1	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	-0.2814333166593027	[54]	[79]	-2	hSpCas9	negative selection	10619991
1461087	1461110	19	+	28162770	SKM1	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	0.45432953042524604	[89]	[217]	4	hSpCas9	negative selection	10619992
1453028	1453051	19	+	28162770	PL21	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-0.31267310047600094	[116]	[40]	-2	hSpCas9	negative selection	10789353
1453297	1453320	19	+	28162770	PL21	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-0.8639907229303954	[45]	[10]	-5	hSpCas9	negative selection	10789354
1453315	1453338	19	+	28162770	PL21	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	0.11383976809509991	[154]	[72]	1	hSpCas9	negative selection	10789355
1455164	1455187	19	+	28162770	PL21	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-0.48267020962998075	[121]	[37]	-3	hSpCas9	negative selection	10789356
1457076	1457099	19	-	28162770	PL21	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	0.23220082372161865	[177]	[90]	2	hSpCas9	negative selection	10789357
1461087	1461110	19	+	28162770	PL21	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	1.1014553396299136	[241]	[225]	8	hSpCas9	negative selection	10789358
1453028	1453051	19	+	28162770	P31FUJ	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-1.905227546385874	[152]	[47]	-8	hSpCas9	negative selection	10958719
1453297	1453320	19	+	28162770	P31FUJ	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-0.8608334270274205	[33]	[21]	-6	hSpCas9	negative selection	10958720
1453315	1453338	19	+	28162770	P31FUJ	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	0.20284557453975144	[138]	[187]	2	hSpCas9	negative selection	10958721
1455164	1455187	19	+	28162770	P31FUJ	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-1.6602234281490549	[77]	[28]	-8	hSpCas9	negative selection	10958722
1457076	1457099	19	-	28162770	P31FUJ	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	0.311926371504102	[302]	[441]	3	hSpCas9	negative selection	10958723
1461087	1461110	19	+	28162770	P31FUJ	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	-0.39077789725505596	[510]	[457]	-4	hSpCas9	negative selection	10958724
1453028	1453051	19	+	28162770	OCIAML5	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-1.893093839124052	[106]	[51]	-7	hSpCas9	negative selection	11128085
1453297	1453320	19	+	28162770	OCIAML5	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-5.099994084307582	[18]	[0]	-9	hSpCas9	negative selection	11128086
1453315	1453338	19	+	28162770	OCIAML5	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	-1.0721923852285	[105]	[90]	-6	hSpCas9	negative selection	11128087
1455164	1455187	19	+	28162770	OCIAML5	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-1.8731281863918265	[68]	[33]	-7	hSpCas9	negative selection	11128088
1457076	1457099	19	-	28162770	OCIAML5	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	0.2001296402614315	[94]	[196]	1	hSpCas9	negative selection	11128089
1461087	1461110	19	+	28162770	OCIAML5	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	-0.9675437882839328	[259]	[239]	-6	hSpCas9	negative selection	11128090
1453028	1453051	19	+	28162770	EOL1	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-2.125082996154066	[206]	[24]	-8	hSpCas9	negative selection	11297451
1453297	1453320	19	+	28162770	EOL1	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-0.22431561434394798	[50]	[22]	-2	hSpCas9	negative selection	11297452
1453315	1453338	19	+	28162770	EOL1	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	-0.4233755318497723	[307]	[120]	-3	hSpCas9	negative selection	11297453
1455164	1455187	19	+	28162770	EOL1	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-2.707720443928978	[185]	[14]	-9	hSpCas9	negative selection	11297454
1457076	1457099	19	-	28162770	EOL1	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	1.3097577041928212	[280]	[366]	9	hSpCas9	negative selection	11297455
1461087	1461110	19	+	28162770	EOL1	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	0.8804006678861522	[364]	[353]	7	hSpCas9	negative selection	11297456
1453028	1453051	19	+	28162770	MOLM13	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-2.6947308192745	[196]	[21]	-8	hSpCas9	negative selection	11466817
1453297	1453320	19	+	28162770	MOLM13	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-4.390091613582994	[28]	[0]	-9	hSpCas9	negative selection	11466818
1453315	1453338	19	+	28162770	MOLM13	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	-0.4735584361003081	[168]	[87]	-3	hSpCas9	negative selection	11466819
1455164	1455187	19	+	28162770	MOLM13	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-6.712019708470356	[144]	[0]	-9	hSpCas9	negative selection	11466820
1457076	1457099	19	-	28162770	MOLM13	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	-0.086046223555953	[275]	[187]	0	hSpCas9	negative selection	11466821
1461087	1461110	19	+	28162770	MOLM13	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	0.023670856853788436	[282]	[207]	0	hSpCas9	negative selection	11466822
1453028	1453051	19	+	28162770	HEL	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-0.12531443994994612	[171]	[100]	-1	hSpCas9	negative selection	11636183
1453297	1453320	19	+	28162770	HEL	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-4.566714533628593	[36]	[0]	-9	hSpCas9	negative selection	11636184
1453315	1453338	19	+	28162770	HEL	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	1.000632424175592	[205]	[263]	8	hSpCas9	negative selection	11636185
1455164	1455187	19	+	28162770	HEL	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-1.8986344001731164	[162]	[27]	-7	hSpCas9	negative selection	11636186
1457076	1457099	19	-	28162770	HEL	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	-0.34051790416506644	[256]	[129]	-2	hSpCas9	negative selection	11636187
1461087	1461110	19	+	28162770	HEL	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	0.7128999034177579	[300]	[315]	6	hSpCas9	negative selection	11636188
1453028	1453051	19	+	28162770	MV411	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-2.0130899994404436	[114]	[23]	-8	hSpCas9	negative selection	11805549
1453297	1453320	19	+	28162770	MV411	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-3.361371691892748	[60]	[4]	-9	hSpCas9	negative selection	11805550
1453315	1453338	19	+	28162770	MV411	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	0.4544820077857873	[161]	[186]	4	hSpCas9	negative selection	11805551
1455164	1455187	19	+	28162770	MV411	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-2.559917371274829	[83]	[11]	-9	hSpCas9	negative selection	11805552
1457076	1457099	19	-	28162770	MV411	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	0.28350680549029705	[157]	[161]	2	hSpCas9	negative selection	11805553
1461087	1461110	19	+	28162770	MV411	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	-0.10331919716380572	[277]	[217]	-1	hSpCas9	negative selection	11805554
1453028	1453051	19	+	28162770	MONOMAC1	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-0.6169401015102136	[98]	[73]	-5	hSpCas9	negative selection	11974915
1453297	1453320	19	+	28162770	MONOMAC1	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-0.9132438810589623	[22]	[13]	-6	hSpCas9	negative selection	11974916
1453315	1453338	19	+	28162770	MONOMAC1	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	-0.4976963251932649	[100]	[81]	-4	hSpCas9	negative selection	11974917
1455164	1455187	19	+	28162770	MONOMAC1	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-2.219404660088008	[64]	[15]	-9	hSpCas9	negative selection	11974918
1457076	1457099	19	-	28162770	MONOMAC1	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	-0.1970368470595539	[124]	[124]	-2	hSpCas9	negative selection	11974919
1461087	1461110	19	+	28162770	MONOMAC1	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	-0.14017451010387738	[198]	[206]	-1	hSpCas9	negative selection	11974920
1453028	1453051	19	+	28162770	OCIAML2	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-1.111548731937333	[22]	[58]	-6	hSpCas9	negative selection	12144281
1453297	1453320	19	+	28162770	OCIAML2	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-1.5961607073260202	[5]	[10]	-7	hSpCas9	negative selection	12144282
1453315	1453338	19	+	28162770	OCIAML2	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	-0.7019553713486169	[26]	[91]	-5	hSpCas9	negative selection	12144283
1455164	1455187	19	+	28162770	OCIAML2	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-4.718557338685747	[18]	[3]	-9	hSpCas9	negative selection	12144284
1457076	1457099	19	-	28162770	OCIAML2	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	0.1503119725845617	[32]	[202]	1	hSpCas9	negative selection	12144285
1461087	1461110	19	+	28162770	OCIAML2	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	0.114332675478995	[45]	[275]	1	hSpCas9	negative selection	12144286
1453028	1453051	19	+	28162770	OCIAML3	viability	GCAGCTGGTGAGGCAGGTGGAGG	APC2	ENSG00000115266	-0.6537138864484309	[36]	[70]	-5	hSpCas9	negative selection	12313647
1453297	1453320	19	+	28162770	OCIAML3	viability	GGTGTCCTCGGGGCAGACGGAGG	APC2	ENSG00000115266	-2.1085808131539214	[9]	[6]	-8	hSpCas9	negative selection	12313648
1453315	1453338	19	+	28162770	OCIAML3	viability	GGAGGTGCTGGAGCAGCTGAAGG	APC2	ENSG00000115266	-0.4317362114252861	[41]	[93]	-3	hSpCas9	negative selection	12313649
1455164	1455187	19	+	28162770	OCIAML3	viability	TGAGATTGAGAAGGAGGAGAAGG	APC2	ENSG00000115266	-0.7600175917630927	[22]	[40]	-5	hSpCas9	negative selection	12313650
1457076	1457099	19	-	28162770	OCIAML3	viability	GATGTTGTGCAGCGCCGCGTTGG	APC2	ENSG00000115266	0.008656862130451862	[53]	[163]	0	hSpCas9	negative selection	12313651
1461087	1461110	19	+	28162770	OCIAML3	viability	CAAGAAGGTGCTGAGGGAGGCGG	APC2	ENSG00000115266	-0.2720795454368009	[107]	[269]	-2	hSpCas9	negative selection	12313652