Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 673
• Symbol: BRAF
• Description: B-Raf proto-oncogene, serine/threonine kinase

DataSource: http://genomecrispr.dkfz.de/#!/results/BRAF

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
140924684	140924707	7	-	26472758	Jiyoye	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	0.7165034396136022	[45]	[56]	5	hSpCas9	negative selection	15904
140924584	140924607	7	+	26472758	Jiyoye	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.1130814298274675	[217]	[151]	-1	hSpCas9	negative selection	15905
140800358	140800381	7	+	26472758	Jiyoye	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.4001795405517308	[328]	[187]	-3	hSpCas9	negative selection	15906
140783108	140783131	7	+	26472758	Jiyoye	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	1.087557447305712	[155]	[249]	7	hSpCas9	negative selection	15907
140924640	140924663	7	-	26472758	Jiyoye	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	0.09683526089372285	[247]	[199]	0	hSpCas9	negative selection	15908
140924625	140924648	7	-	26472758	Jiyoye	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	0.05353842689117305	[91]	[71]	0	hSpCas9	negative selection	15909
140834615	140834638	7	-	26472758	Jiyoye	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-0.07680947149046191	[199]	[142]	0	hSpCas9	negative selection	15910
140801443	140801466	7	+	26472758	Jiyoye	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.6569549559138423	[114]	[54]	-5	hSpCas9	negative selection	15911
140800429	140800452	7	-	26472758	Jiyoye	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	0.24581239356698503	[188]	[168]	1	hSpCas9	negative selection	15912
140794410	140794433	7	+	26472758	Jiyoye	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	-1.321522596676732	[115]	[34]	-7	hSpCas9	negative selection	15913
140924684	140924707	7	-	26472758	KBM7	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-0.8768381215556165	[109,112]	[14,40]	-6	hSpCas9	negative selection	207022
140924584	140924607	7	+	26472758	KBM7	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	0.27582532522418957	[837,677]	[467,393]	3	hSpCas9	negative selection	207023
140800358	140800381	7	+	26472758	KBM7	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.21898427013867083	[600,363]	[235,278]	2	hSpCas9	negative selection	207024
140783108	140783131	7	+	26472758	KBM7	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	0.001896905002216176	[772,572]	[330,297]	0	hSpCas9	negative selection	207025
140924640	140924663	7	-	26472758	KBM7	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-0.34086796055388313	[611,368]	[161,192]	-3	hSpCas9	negative selection	207026
140924625	140924648	7	-	26472758	KBM7	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	-0.16848344166037543	[395,186]	[144,93]	-2	hSpCas9	negative selection	207027
140834615	140834638	7	-	26472758	KBM7	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	0.9424548410453216	[699,748]	[1063,298]	8	hSpCas9	negative selection	207028
140801443	140801466	7	+	26472758	KBM7	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.47703728434044324	[432,329]	[132,122]	-4	hSpCas9	negative selection	207029
140800429	140800452	7	-	26472758	KBM7	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	-0.4076819119136278	[620,525]	[248,160]	-4	hSpCas9	negative selection	207030
140794410	140794433	7	+	26472758	KBM7	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	0.015648411928737727	[409,436]	[241,167]	0	hSpCas9	negative selection	207031
140924684	140924707	7	-	26472758	Raji	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	0.3885652879176529	[78]	[23]	3	hSpCas9	negative selection	398140
140924584	140924607	7	+	26472758	Raji	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.6889373364090279	[520]	[74]	-5	hSpCas9	negative selection	398141
140800358	140800381	7	+	26472758	Raji	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.45204387324041906	[223]	[37]	-4	hSpCas9	negative selection	398142
140783108	140783131	7	+	26472758	Raji	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	0.9300790035656896	[293]	[129]	8	hSpCas9	negative selection	398143
140924640	140924663	7	-	26472758	Raji	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	0.6563478378573586	[256]	[93]	6	hSpCas9	negative selection	398144
140924625	140924648	7	-	26472758	Raji	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	0.45103640141567786	[144]	[45]	4	hSpCas9	negative selection	398145
140834615	140834638	7	-	26472758	Raji	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	0.08852450812228374	[307]	[75]	0	hSpCas9	negative selection	398146
140801443	140801466	7	+	26472758	Raji	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.33073757701828566	[167]	[30]	-3	hSpCas9	negative selection	398147
140800429	140800452	7	-	26472758	Raji	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	-0.023320156270994374	[253]	[57]	0	hSpCas9	negative selection	398148
140794410	140794433	7	+	26472758	Raji	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	-0.9606618520494993	[368]	[43]	-6	hSpCas9	negative selection	398149
140924684	140924707	7	-	26472758	K562	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	0.7107367318889839	[75]	[104]	6	hSpCas9	negative selection	589258
140924584	140924607	7	+	26472758	K562	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-1.1852231845211687	[694]	[257]	-6	hSpCas9	negative selection	589259
140800358	140800381	7	+	26472758	K562	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.493953687714005	[341]	[204]	-3	hSpCas9	negative selection	589260
140783108	140783131	7	+	26472758	K562	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	0.012056017575070688	[483]	[411]	0	hSpCas9	negative selection	589261
140924640	140924663	7	-	26472758	K562	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-0.5208448609021245	[531]	[312]	-3	hSpCas9	negative selection	589262
140924625	140924648	7	-	26472758	K562	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	0.004665145668561577	[208]	[176]	0	hSpCas9	negative selection	589263
140834615	140834638	7	-	26472758	K562	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-0.28859893039727585	[640]	[442]	-2	hSpCas9	negative selection	589264
140801443	140801466	7	+	26472758	K562	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.30897369405383945	[225]	[153]	-2	hSpCas9	negative selection	589265
140800429	140800452	7	-	26472758	K562	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	-0.2341724692543055	[378]	[271]	-2	hSpCas9	negative selection	589266
140794410	140794433	7	+	26472758	K562	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	-0.5089413047504278	[353]	[209]	-3	hSpCas9	negative selection	589267
140800358	140800381	7	+	26627737	DLD1	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.14008074621516975	[250]	[81,46,122]	1	hSpCas9	negative selection	835223
140800435	140800458	7	-	26627737	DLD1	viability	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.23367689823375204	[803]	[141,238,254]	-2	hSpCas9	negative selection	835224
140801443	140801466	7	+	26627737	DLD1	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.5349556183862718	[569]	[179,148,51]	-5	hSpCas9	negative selection	835225
140834720	140834743	7	+	26627737	DLD1	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	1.0918421495477288	[256]	[82,159,256]	8	hSpCas9	negative selection	835226
140924557	140924580	7	+	26627737	DLD1	viability	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.6564866254750885	[1004]	[229,175,191]	-6	hSpCas9	negative selection	835227
140924562	140924585	7	+	26627737	DLD1	viability	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-1.0596800722806858	[1071]	[202,201,89]	-7	hSpCas9	negative selection	835228
140800358	140800381	7	+	26627737	GBM cells	viability after 5 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.22966582016005416	[162]	[89,114]	3	hSpCas9	negative selection	917538
140800435	140800458	7	-	26627737	GBM cells	viability after 5 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.28460019130458164	[359]	[170,145]	-4	hSpCas9	negative selection	917539
140801443	140801466	7	+	26627737	GBM cells	viability after 5 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.5823221140699602	[274]	[76,119]	-7	hSpCas9	negative selection	917540
140834720	140834743	7	+	26627737	GBM cells	viability after 5 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.3057481678319278	[309]	[110,157]	-5	hSpCas9	negative selection	917541
140924557	140924580	7	+	26627737	GBM cells	viability after 5 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.4787874731201855	[355]	[121,151]	-6	hSpCas9	negative selection	917542
140924562	140924585	7	+	26627737	GBM cells	viability after 5 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.6828603482044231	[225]	[67,82]	-8	hSpCas9	negative selection	917543
140800358	140800381	7	+	26627737	GBM cells	viability after 13 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.06825856320106449	[162]	[101,69]	-1	hSpCas9	negative selection	999853
140800435	140800458	7	-	26627737	GBM cells	viability after 13 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.2297346260939675	[359]	[213,127]	-3	hSpCas9	negative selection	999854
140801443	140801466	7	+	26627737	GBM cells	viability after 13 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.517993578530007	[274]	[85,118]	-6	hSpCas9	negative selection	999855
140834720	140834743	7	+	26627737	GBM cells	viability after 13 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.4351274431229429	[309]	[178,79]	-5	hSpCas9	negative selection	999856
140924557	140924580	7	+	26627737	GBM cells	viability after 13 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.9606351102449928	[355]	[117,83]	-8	hSpCas9	negative selection	999857
140924562	140924585	7	+	26627737	GBM cells	viability after 13 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-1.5518329304676644	[225]	[32,48]	-9	hSpCas9	negative selection	999858
140800358	140800381	7	+	26627737	GBM cells	viability after 21 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.6058250380477572	[162]	[151,118]	6	hSpCas9	negative selection	1082168
140800435	140800458	7	-	26627737	GBM cells	viability after 21 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	0.007173534534129722	[359]	[206,186]	0	hSpCas9	negative selection	1082169
140801443	140801466	7	+	26627737	GBM cells	viability after 21 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	0.2735995737971324	[274]	[189,171]	3	hSpCas9	negative selection	1082170
140834720	140834743	7	+	26627737	GBM cells	viability after 21 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.5219685666619855	[309]	[133,101]	-5	hSpCas9	negative selection	1082171
140924557	140924580	7	+	26627737	GBM cells	viability after 21 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.2277213848854075	[355]	[172,157]	-2	hSpCas9	negative selection	1082172
140924562	140924585	7	+	26627737	GBM cells	viability after 21 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.6104233667566653	[225]	[93,67]	-5	hSpCas9	negative selection	1082173
140800358	140800381	7	+	26627737	RPE1	viability after 9 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.02245424378189209	[443]	[169,103]	0	hSpCas9	negative selection	1164483
140800435	140800458	7	-	26627737	RPE1	viability after 9 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.41277275896529264	[1947]	[358,585]	-3	hSpCas9	negative selection	1164484
140801443	140801466	7	+	26627737	RPE1	viability after 9 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-1.1943972318282812	[1866]	[240,273]	-7	hSpCas9	negative selection	1164485
140834720	140834743	7	+	26627737	RPE1	viability after 9 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.4214645095396231	[820]	[180,205]	-3	hSpCas9	negative selection	1164486
140924557	140924580	7	+	26627737	RPE1	viability after 9 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	0.59663226372728	[931]	[366,536]	4	hSpCas9	negative selection	1164487
140924562	140924585	7	+	26627737	RPE1	viability after 9 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-1.0643050452172773	[1683]	[214,299]	-6	hSpCas9	negative selection	1164488
140800358	140800381	7	+	26627737	RPE1	viability after 12 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.8078139207290608	[443]	[89,44]	-5	hSpCas9	negative selection	1246798
140800435	140800458	7	-	26627737	RPE1	viability after 12 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.27840203856977297	[1947]	[295,574]	-2	hSpCas9	negative selection	1246799
140801443	140801466	7	+	26627737	RPE1	viability after 12 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-1.125442500142674	[1866]	[226,232]	-6	hSpCas9	negative selection	1246800
140834720	140834743	7	+	26627737	RPE1	viability after 12 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.3493079386893203	[820]	[177,167]	-2	hSpCas9	negative selection	1246801
140924557	140924580	7	+	26627737	RPE1	viability after 12 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	0.2730572189535899	[931]	[253,353]	1	hSpCas9	negative selection	1246802
140924562	140924585	7	+	26627737	RPE1	viability after 12 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.9431199137059704	[1683]	[262,205]	-6	hSpCas9	negative selection	1246803
140800358	140800381	7	+	26627737	RPE1	viability after 15 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.011040521688980953	[443]	[172,77]	0	hSpCas9	negative selection	1329113
140800435	140800458	7	-	26627737	RPE1	viability after 15 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-1.0970301683233705	[1947]	[279,235]	-6	hSpCas9	negative selection	1329114
140801443	140801466	7	+	26627737	RPE1	viability after 15 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-1.3341378771098382	[1866]	[210,207]	-7	hSpCas9	negative selection	1329115
140834720	140834743	7	+	26627737	RPE1	viability after 15 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.6961301523181527	[820]	[151,134]	-4	hSpCas9	negative selection	1329116
140924557	140924580	7	+	26627737	RPE1	viability after 15 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.06986676267220188	[931]	[212,287]	0	hSpCas9	negative selection	1329117
140924562	140924585	7	+	26627737	RPE1	viability after 15 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.7579511915382567	[1683]	[298,264]	-5	hSpCas9	negative selection	1329118
140800358	140800381	7	+	26627737	RPE1	viability after 18 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-1.5124301834706033	[443]	[41,41]	-7	hSpCas9	negative selection	1411428
140800435	140800458	7	-	26627737	RPE1	viability after 18 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.40153662067956175	[1947]	[382,413]	-3	hSpCas9	negative selection	1411429
140801443	140801466	7	+	26627737	RPE1	viability after 18 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-1.066447428959393	[1866]	[242,237]	-6	hSpCas9	negative selection	1411430
140834720	140834743	7	+	26627737	RPE1	viability after 18 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.4848065285794906	[820]	[196,116]	-3	hSpCas9	negative selection	1411431
140924557	140924580	7	+	26627737	RPE1	viability after 18 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	0.24380144496606015	[931]	[350,240]	1	hSpCas9	negative selection	1411432
140924562	140924585	7	+	26627737	RPE1	viability after 18 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.6555925043120879	[1683]	[302,272]	-4	hSpCas9	negative selection	1411433
140800358	140800381	7	+	26627737	HeLa	viability after 8 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.8007219501164943	[132]	[83,102,110]	6	hSpCas9	negative selection	1493743
140800435	140800458	7	-	26627737	HeLa	viability after 8 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.7525627752719888	[739]	[369,99,145]	-6	hSpCas9	negative selection	1493744
140801443	140801466	7	+	26627737	HeLa	viability after 8 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	0.05358289782789885	[416]	[277,122,183]	0	hSpCas9	negative selection	1493745
140834720	140834743	7	+	26627737	HeLa	viability after 8 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.15528441048542965	[455]	[146,298,201]	1	hSpCas9	negative selection	1493746
140924557	140924580	7	+	26627737	HeLa	viability after 8 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.7715233755358539	[578]	[169,104,170]	-6	hSpCas9	negative selection	1493747
140924562	140924585	7	+	26627737	HeLa	viability after 8 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	0.3392927295502204	[441]	[210,166,337]	3	hSpCas9	negative selection	1493748
140800358	140800381	7	+	26627737	HeLa	viability after 12 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	1.0668627338035177	[132]	[56,140,142]	7	hSpCas9	negative selection	1576058
140800435	140800458	7	-	26627737	HeLa	viability after 12 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.35969516393880685	[739]	[275,191,252]	-3	hSpCas9	negative selection	1576059
140801443	140801466	7	+	26627737	HeLa	viability after 12 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.3240121174660914	[416]	[83,188,132]	-3	hSpCas9	negative selection	1576060
140834720	140834743	7	+	26627737	HeLa	viability after 12 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.8057844225053338	[455]	[132,127,60]	-6	hSpCas9	negative selection	1576061
140924557	140924580	7	+	26627737	HeLa	viability after 12 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-1.2209959433317619	[578]	[62,128,111]	-8	hSpCas9	negative selection	1576062
140924562	140924585	7	+	26627737	HeLa	viability after 12 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.3770976160311197	[441]	[95,108,218]	-3	hSpCas9	negative selection	1576063
140800358	140800381	7	+	26627737	HeLa	viability after 15 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	1.3257896584371516	[132]	[81,103,228]	8	hSpCas9	negative selection	1658373
140800435	140800458	7	-	26627737	HeLa	viability after 15 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	0.02495620401572718	[739]	[166,463,288]	0	hSpCas9	negative selection	1658374
140801443	140801466	7	+	26627737	HeLa	viability after 15 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.24384961871451347	[416]	[110,145,175]	-2	hSpCas9	negative selection	1658375
140834720	140834743	7	+	26627737	HeLa	viability after 15 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.4335800704388132	[455]	[91,218,98]	-4	hSpCas9	negative selection	1658376
140924557	140924580	7	+	26627737	HeLa	viability after 15 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.279929237291705	[578]	[204,101,281]	-2	hSpCas9	negative selection	1658377
140924562	140924585	7	+	26627737	HeLa	viability after 15 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.03931420777026928	[441]	[185,153,185]	0	hSpCas9	negative selection	1658378
140800358	140800381	7	+	26627737	HeLa	viability after 18 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	1.3393270434428184	[132]	[55,87,228]	8	hSpCas9	negative selection	1740688
140800435	140800458	7	-	26627737	HeLa	viability after 18 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	0.0579335725280643	[739]	[125,383,288]	0	hSpCas9	negative selection	1740689
140801443	140801466	7	+	26627737	HeLa	viability after 18 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.19998342485420095	[416]	[82,120,175]	-2	hSpCas9	negative selection	1740690
140834720	140834743	7	+	26627737	HeLa	viability after 18 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.3899931032035162	[455]	[66,184,98]	-3	hSpCas9	negative selection	1740691
140924557	140924580	7	+	26627737	HeLa	viability after 18 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.280369662840432	[578]	[136,84,281]	-2	hSpCas9	negative selection	1740692
140924562	140924585	7	+	26627737	HeLa	viability after 18 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.0275561565129967	[441]	[123,131,185]	0	hSpCas9	negative selection	1740693
140800358	140800381	7	+	26627737	HCT116	viability after 6 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.6523070209502707	[313]	[45,94]	3	hSpCas9	negative selection	1823003
140800435	140800458	7	-	26627737	HCT116	viability after 6 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	0.9781803544888769	[838]	[322,224]	5	hSpCas9	negative selection	1823004
140801443	140801466	7	+	26627737	HCT116	viability after 6 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	0.6634229264779976	[472]	[285,24]	3	hSpCas9	negative selection	1823005
140834720	140834743	7	+	26627737	HCT116	viability after 6 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-1.233903284023555	[523]	[25,39]	-6	hSpCas9	negative selection	1823006
140924557	140924580	7	+	26627737	HCT116	viability after 6 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.8200141235561608	[1156]	[200,48]	-5	hSpCas9	negative selection	1823007
140924562	140924585	7	+	26627737	HCT116	viability after 6 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	0.24448006602624817	[556]	[95,107]	1	hSpCas9	negative selection	1823008
140800358	140800381	7	+	26627737	HCT116	viability after 8 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-1.0535831658196018	[303]	[54,134,51]	-8	hSpCas9	negative selection	1905318
140800435	140800458	7	-	26627737	HCT116	viability after 8 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.8487831115515109	[696]	[197,187,252]	-8	hSpCas9	negative selection	1905319
140801443	140801466	7	+	26627737	HCT116	viability after 8 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-1.0902827347210362	[401]	[96,111,102]	-8	hSpCas9	negative selection	1905320
140834720	140834743	7	+	26627737	HCT116	viability after 8 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.41468291722393547	[199]	[104,190,143]	4	hSpCas9	negative selection	1905321
140924557	140924580	7	+	26627737	HCT116	viability after 8 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.1543907635185469	[357]	[205,127,197]	-2	hSpCas9	negative selection	1905322
140924562	140924585	7	+	26627737	HCT116	viability after 8 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.1255253499041475	[254]	[148,127,109]	-1	hSpCas9	negative selection	1905323
140800358	140800381	7	+	26627737	HCT116	viability after 9 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-1.5352398541624948	[313]	[62,1]	-8	hSpCas9	negative selection	1987633
140800435	140800458	7	-	26627737	HCT116	viability after 9 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	0.6528172346847408	[838]	[268,417]	5	hSpCas9	negative selection	1987634
140801443	140801466	7	+	26627737	HCT116	viability after 9 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.28114192426560025	[472]	[156,61]	-2	hSpCas9	negative selection	1987635
140834720	140834743	7	+	26627737	HCT116	viability after 9 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-1.984372117867736	[523]	[50,22]	-8	hSpCas9	negative selection	1987636
140924557	140924580	7	+	26627737	HCT116	viability after 9 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.8447674601228701	[1156]	[271,92]	-5	hSpCas9	negative selection	1987637
140924562	140924585	7	+	26627737	HCT116	viability after 9 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-2.492306416663279	[556]	[7,40]	-9	hSpCas9	negative selection	1987638
140800358	140800381	7	+	26627737	HCT116	viability after 12 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-1.5881975253991967	[303]	[13,100,48]	-9	hSpCas9	negative selection	2069948
140800435	140800458	7	-	26627737	HCT116	viability after 12 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-1.2606099523827465	[696]	[155,137,163]	-8	hSpCas9	negative selection	2069949
140801443	140801466	7	+	26627737	HCT116	viability after 12 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-1.6682656230945554	[401]	[15,72,114]	-9	hSpCas9	negative selection	2069950
140834720	140834743	7	+	26627737	HCT116	viability after 12 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.1383864275578141	[199]	[106,122,117]	1	hSpCas9	negative selection	2069951
140924557	140924580	7	+	26627737	HCT116	viability after 12 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.2787949135163889	[357]	[194,124,140]	-3	hSpCas9	negative selection	2069952
140924562	140924585	7	+	26627737	HCT116	viability after 12 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	0.21027654205366403	[254]	[155,153,154]	2	hSpCas9	negative selection	2069953
140800358	140800381	7	+	26627737	HCT116	viability after 15 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-1.1808021434938765	[303]	[55,138,33]	-8	hSpCas9	negative selection	2152263
140800435	140800458	7	-	26627737	HCT116	viability after 15 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-1.3383988397823208	[696]	[115,133,218]	-8	hSpCas9	negative selection	2152264
140801443	140801466	7	+	26627737	HCT116	viability after 15 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-1.4503481737649695	[401]	[91,47,113]	-8	hSpCas9	negative selection	2152265
140834720	140834743	7	+	26627737	HCT116	viability after 15 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.24794345125025335	[199]	[134,135,137]	2	hSpCas9	negative selection	2152266
140924557	140924580	7	+	26627737	HCT116	viability after 15 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.2690920771011086	[357]	[187,158,166]	-3	hSpCas9	negative selection	2152267
140924562	140924585	7	+	26627737	HCT116	viability after 15 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.3542408052835422	[254]	[162,106,79]	-4	hSpCas9	negative selection	2152268
140800358	140800381	7	+	26627737	HCT116	viability after 18 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-1.6111590903517814	[303]	[3,68,70]	-8	hSpCas9	negative selection	2234578
140800435	140800458	7	-	26627737	HCT116	viability after 18 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-1.2306782365350286	[696]	[122,149,157]	-8	hSpCas9	negative selection	2234579
140801443	140801466	7	+	26627737	HCT116	viability after 18 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-1.8939347254303764	[401]	[85,45,23]	-9	hSpCas9	negative selection	2234580
140834720	140834743	7	+	26627737	HCT116	viability after 18 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.21880806237638734	[199]	[74,149,109]	2	hSpCas9	negative selection	2234581
140924557	140924580	7	+	26627737	HCT116	viability after 18 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.5916081048224828	[357]	[94,84,168]	-5	hSpCas9	negative selection	2234582
140924562	140924585	7	+	26627737	HCT116	viability after 18 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.506734888494729	[254]	[119,49,92]	-4	hSpCas9	negative selection	2234583
140924557	140924580	7	+	24336569	HL60	viability	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	0.32734144493843287	[144]	[384]	3	hSpCas9	negative selection	2250249
140924562	140924585	7	+	24336569	HL60	viability	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-1.3634400701161504	[1103]	[907]	-8	hSpCas9	negative selection	2250250
140924568	140924591	7	-	24336569	HL60	viability	TGCGGACCCTGCCATTCCGGAGG	BRAF	ENSG00000157764	0.950435983837391	[122]	[502]	7	hSpCas9	negative selection	2250251
140924578	140924601	7	+	24336569	HL60	viability	GGCAGGGTCCGCAGCCGAAGAGG	BRAF	ENSG00000157764	0.10739271682379181	[714]	[1629]	1	hSpCas9	negative selection	2250252
140924584	140924607	7	+	24336569	HL60	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.38940490208724127	[756]	[1222]	-3	hSpCas9	negative selection	2250253
140924590	140924613	7	+	24336569	HL60	viability	AGCCGAAGAGGCCGCGGCGCCGG	BRAF	ENSG00000157764	0.4074801911491565	[672]	[1888]	4	hSpCas9	negative selection	2250254
140924615	140924638	7	-	24336569	HL60	viability	ATGGAGCCCGAGGCCGGCGCCGG	BRAF	ENSG00000157764	-0.8565906897886932	[1078]	[1260]	-7	hSpCas9	negative selection	2250255
140924641	140924664	7	-	24336569	HL60	viability	CGGGCCAGGCTCTGTTCAACGGG	BRAF	ENSG00000157764	0.7797838294239098	[288]	[1049]	6	hSpCas9	negative selection	2250256
140924672	140924695	7	-	24336569	HL60	viability	CTGAGCGGTGGCGGTGGTGGCGG	BRAF	ENSG00000157764	1.2674607266364835	[179]	[916]	8	hSpCas9	negative selection	2250257
140924684	140924707	7	-	24336569	HL60	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-0.9433016615713716	[397]	[437]	-7	hSpCas9	negative selection	2250258
140924557	140924580	7	+	24336569	KBM7	viability	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-1.7089072804322731	[337]	[281]	-8	hSpCas9	negative selection	2317426
140924562	140924585	7	+	24336569	KBM7	viability	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.6728989676368534	[739]	[1265]	-5	hSpCas9	negative selection	2317427
140924568	140924591	7	-	24336569	KBM7	viability	TGCGGACCCTGCCATTCCGGAGG	BRAF	ENSG00000157764	-0.0505639674670732	[291]	[768]	0	hSpCas9	negative selection	2317428
140924578	140924601	7	+	24336569	KBM7	viability	GGCAGGGTCCGCAGCCGAAGAGG	BRAF	ENSG00000157764	-0.05350131590568474	[545]	[1434]	0	hSpCas9	negative selection	2317429
140924584	140924607	7	+	24336569	KBM7	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	0.5933859361278611	[433]	[1785]	5	hSpCas9	negative selection	2317430
140924590	140924613	7	+	24336569	KBM7	viability	AGCCGAAGAGGCCGCGGCGCCGG	BRAF	ENSG00000157764	-0.2903455140501919	[646]	[1442]	-2	hSpCas9	negative selection	2317431
140924615	140924638	7	-	24336569	KBM7	viability	ATGGAGCCCGAGGCCGGCGCCGG	BRAF	ENSG00000157764	0.5080056558517149	[535]	[2078]	4	hSpCas9	negative selection	2317432
140924641	140924664	7	-	24336569	KBM7	viability	CGGGCCAGGCTCTGTTCAACGGG	BRAF	ENSG00000157764	0.447723424784424	[299]	[1115]	4	hSpCas9	negative selection	2317433
140924672	140924695	7	-	24336569	KBM7	viability	CTGAGCGGTGGCGGTGGTGGCGG	BRAF	ENSG00000157764	-0.8333628908526123	[357]	[547]	-6	hSpCas9	negative selection	2317434
140924684	140924707	7	-	24336569	KBM7	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-1.4619344895259525	[504]	[499]	-7	hSpCas9	negative selection	2317435
140847537	140847560	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGTGCCACTGCACTCCAGCCCGG	BRAF	ENSG00000157764	0.4846974014178431	[92,26]	[27,6]	2	dCas9-VP64	positive selection	2390992
140888749	140888772	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCTTGAATCTGGGAGGTGGAGG	BRAF	ENSG00000157764	-1.2170301128578451	[158,55]	[16,1]	-7	dCas9-VP64	positive selection	2396436
140812176	140812199	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGTGTGTGTGTGTGTGAGGG	BRAF	ENSG00000157764	2.740144461675261	[44,53]	[104,38]	8	dCas9-VP64	positive selection	2402680
140815345	140815368	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACCATCTTGGCTAACAAGG	BRAF	ENSG00000157764	-0.8978621526762642	[150,655]	[5,91]	-5	dCas9-VP64	positive selection	2460983
140811131	140811154	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACAGAAACACACACAAAACAAGG	BRAF	ENSG00000157764	0.6983877191407553	[100,554]	[44,196]	3	dCas9-VP64	positive selection	2464845
140781083	140781106	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGTGTGGAAG	BRAF	ENSG00000157764	-2.5797701712444865	[504,29]	[12,4]	-9	dCas9-VP64	positive selection	2473351
140847537	140847560	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGTGCCACTGCACTCCAGCCCGG	BRAF	ENSG00000157764	0.6971910689480432	[49,47]	[24,25]	5	dCas9-VP64	positive selection	2486247
140888749	140888772	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCTTGAATCTGGGAGGTGGAGG	BRAF	ENSG00000157764	0.32775181017134025	[33,80]	[21,23]	2	dCas9-VP64	positive selection	2491691
140812176	140812199	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGTGTGTGTGTGTGTGAGGG	BRAF	ENSG00000157764	-0.0021690128549880505	[109,77]	[41,19]	0	dCas9-VP64	positive selection	2497935
140815345	140815368	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACCATCTTGGCTAACAAGG	BRAF	ENSG00000157764	2.463185390337416	[53,170]	[40,350]	9	dCas9-VP64	positive selection	2556238
140811131	140811154	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACAGAAACACACACAAAACAAGG	BRAF	ENSG00000157764	0.5883286892291487	[139,80]	[45,61]	4	dCas9-VP64	positive selection	2560100
140781083	140781106	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGTGTGGAAG	BRAF	ENSG00000157764	0.3593778947128078	[15,191]	[23,59]	3	dCas9-VP64	positive selection	2568606
140924615	140924638	7	-	27260157	DLD1	viability	ATGGAGCCCGAGGCCGGCGCCGG	BRAF	ENSG00000157764	0.548084935847517	[]	[]	8	hSpCas9	negative selection	2575012
140850155	140850178	7	-	27260157	DLD1	viability	GGAACATATAGAGGCCCTATTGG	BRAF	ENSG00000157764	-0.284967261557621	[]	[]	-2	hSpCas9	negative selection	2575452
140924640	140924663	7	-	27260157	DLD1	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	0.31210274680815	[]	[]	4	hSpCas9	negative selection	2575933
140834710	140834733	7	+	27260157	DLD1	viability	GAGATGAAGGTAGCACTGAAAGG	BRAF	ENSG00000157764	-0.0360743934679322	[]	[]	0	hSpCas9	negative selection	2576999
140924562	140924585	7	+	27260157	DLD1	viability	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.051714396729801	[]	[]	0	hSpCas9	negative selection	2577438
140924568	140924591	7	-	27260157	DLD1	viability	TGCGGACCCTGCCATTCCGGAGG	BRAF	ENSG00000157764	-0.271118633115212	[]	[]	-2	hSpCas9	negative selection	2579860
140924684	140924707	7	-	27260157	DLD1	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	0.575090419123267	[]	[]	8	hSpCas9	negative selection	2579924
140924642	140924665	7	+	27260157	DLD1	viability	CCGTTGAACAGAGCCTGGCCCGG	BRAF	ENSG00000157764	-0.228706675970131	[]	[]	-2	hSpCas9	negative selection	2583317
140924578	140924601	7	+	27260157	DLD1	viability	GGCAGGGTCCGCAGCCGAAGAGG	BRAF	ENSG00000157764	0.311482814088613	[]	[]	4	hSpCas9	negative selection	2584659
140924584	140924607	7	+	27260157	DLD1	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.172862360960274	[]	[]	-1	hSpCas9	negative selection	2586650
140924699	140924722	7	+	27260157	DLD1	viability	GCCATCTTATAACCGAGAGCCGG	BRAF	ENSG00000157764	-0.96275482428027	[]	[]	-7	hSpCas9	negative selection	2587207
140924641	140924664	7	-	27260157	DLD1	viability	CGGGCCAGGCTCTGTTCAACGGG	BRAF	ENSG00000157764	0.731407915887148	[]	[]	8	hSpCas9	negative selection	2587592
140924697	140924720	7	-	27260157	DLD1	viability	GGCTCTCGGTTATAAGATGGCGG	BRAF	ENSG00000157764	-0.319305638407187	[]	[]	-3	hSpCas9	negative selection	2606500
140924571	140924594	7	-	27260157	DLD1	viability	GGCTGCGGACCCTGCCATTCCGG	BRAF	ENSG00000157764	0.728905895629703	[]	[]	8	hSpCas9	negative selection	2607476
140850142	140850165	7	-	27260157	DLD1	viability	GCCCTATTGGACAAATTTGGTGG	BRAF	ENSG00000157764	-0.471222255794005	[]	[]	-4	hSpCas9	negative selection	2619169
140834669	140834692	7	+	27260157	DLD1	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.0519097671627051	[]	[]	0	hSpCas9	negative selection	2619687
140834720	140834743	7	+	27260157	DLD1	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.163928056014867	[]	[]	-1	hSpCas9	negative selection	2645188
140924590	140924613	7	+	27260157	DLD1	viability	AGCCGAAGAGGCCGCGGCGCCGG	BRAF	ENSG00000157764	0.187858967603738	[]	[]	3	hSpCas9	negative selection	2646011
140924672	140924695	7	-	27260157	DLD1	viability	CTGAGCGGTGGCGGTGGTGGCGG	BRAF	ENSG00000157764	-1.01741359088345	[]	[]	-7	hSpCas9	negative selection	2648132
140924557	140924580	7	+	27260157	DLD1	viability	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	0.145026515191506	[]	[]	3	hSpCas9	negative selection	2648671
140924615	140924638	7	-	27260157	HT1080	viability	ATGGAGCCCGAGGCCGGCGCCGG	BRAF	ENSG00000157764	1.46181710804534	[]	[]	9	hSpCas9	negative selection	2651142
140850155	140850178	7	-	27260157	HT1080	viability	GGAACATATAGAGGCCCTATTGG	BRAF	ENSG00000157764	-0.496489566532387	[]	[]	-7	hSpCas9	negative selection	2651582
140924640	140924663	7	-	27260157	HT1080	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-0.310841429153257	[]	[]	-7	hSpCas9	negative selection	2652063
140834710	140834733	7	+	27260157	HT1080	viability	GAGATGAAGGTAGCACTGAAAGG	BRAF	ENSG00000157764	0.438815602849616	[]	[]	4	hSpCas9	negative selection	2653129
140924562	140924585	7	+	27260157	HT1080	viability	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.669289508386685	[]	[]	-8	hSpCas9	negative selection	2653568
140924568	140924591	7	-	27260157	HT1080	viability	TGCGGACCCTGCCATTCCGGAGG	BRAF	ENSG00000157764	-1.20278976900059	[]	[]	-8	hSpCas9	negative selection	2655990
140924684	140924707	7	-	27260157	HT1080	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	0.565735685164549	[]	[]	5	hSpCas9	negative selection	2656054
140924642	140924665	7	+	27260157	HT1080	viability	CCGTTGAACAGAGCCTGGCCCGG	BRAF	ENSG00000157764	-0.184859942580888	[]	[]	0	hSpCas9	negative selection	2659447
140924578	140924601	7	+	27260157	HT1080	viability	GGCAGGGTCCGCAGCCGAAGAGG	BRAF	ENSG00000157764	0.0216901230621618	[]	[]	0	hSpCas9	negative selection	2660789
140924584	140924607	7	+	27260157	HT1080	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-1.81165720893869	[]	[]	-9	hSpCas9	negative selection	2662780
140924699	140924722	7	+	27260157	HT1080	viability	GCCATCTTATAACCGAGAGCCGG	BRAF	ENSG00000157764	0.914094696575718	[]	[]	7	hSpCas9	negative selection	2663337
140924641	140924664	7	-	27260157	HT1080	viability	CGGGCCAGGCTCTGTTCAACGGG	BRAF	ENSG00000157764	0.303772798804342	[]	[]	3	hSpCas9	negative selection	2663722
140924697	140924720	7	-	27260157	HT1080	viability	GGCTCTCGGTTATAAGATGGCGG	BRAF	ENSG00000157764	-0.764659146073853	[]	[]	-8	hSpCas9	negative selection	2682630
140924571	140924594	7	-	27260157	HT1080	viability	GGCTGCGGACCCTGCCATTCCGG	BRAF	ENSG00000157764	-0.57247122298914	[]	[]	-7	hSpCas9	negative selection	2683606
140850142	140850165	7	-	27260157	HT1080	viability	GCCCTATTGGACAAATTTGGTGG	BRAF	ENSG00000157764	0.0463665129071222	[]	[]	0	hSpCas9	negative selection	2695299
140834669	140834692	7	+	27260157	HT1080	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.351771492157522	[]	[]	-7	hSpCas9	negative selection	2695817
140834720	140834743	7	+	27260157	HT1080	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.40851524203329	[]	[]	-7	hSpCas9	negative selection	2721318
140924590	140924613	7	+	27260157	HT1080	viability	AGCCGAAGAGGCCGCGGCGCCGG	BRAF	ENSG00000157764	0.350090511050691	[]	[]	3	hSpCas9	negative selection	2722141
140924672	140924695	7	-	27260157	HT1080	viability	CTGAGCGGTGGCGGTGGTGGCGG	BRAF	ENSG00000157764	-1.98609229482771	[]	[]	-9	hSpCas9	negative selection	2724262
140924557	140924580	7	+	27260157	HT1080	viability	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	0.0613659350580585	[]	[]	0	hSpCas9	negative selection	2724801
140924615	140924638	7	-	27260157	MKN45	viability	ATGGAGCCCGAGGCCGGCGCCGG	BRAF	ENSG00000157764	0.504048278743666	[]	[]	6	hSpCas9	negative selection	2727272
140850155	140850178	7	-	27260157	MKN45	viability	GGAACATATAGAGGCCCTATTGG	BRAF	ENSG00000157764	0.20553374535061	[]	[]	5	hSpCas9	negative selection	2727712
140924640	140924663	7	-	27260157	MKN45	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	0.0738864978789141	[]	[]	0	hSpCas9	negative selection	2728193
140834710	140834733	7	+	27260157	MKN45	viability	GAGATGAAGGTAGCACTGAAAGG	BRAF	ENSG00000157764	1.045896589085	[]	[]	8	hSpCas9	negative selection	2729259
140924562	140924585	7	+	27260157	MKN45	viability	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	0.887189667360601	[]	[]	8	hSpCas9	negative selection	2729698
140924568	140924591	7	-	27260157	MKN45	viability	TGCGGACCCTGCCATTCCGGAGG	BRAF	ENSG00000157764	0.0942542847123342	[]	[]	0	hSpCas9	negative selection	2732120
140924684	140924707	7	-	27260157	MKN45	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	1.1502213933065	[]	[]	8	hSpCas9	negative selection	2732184
140924642	140924665	7	+	27260157	MKN45	viability	CCGTTGAACAGAGCCTGGCCCGG	BRAF	ENSG00000157764	0.248024975858451	[]	[]	5	hSpCas9	negative selection	2735577
140924578	140924601	7	+	27260157	MKN45	viability	GGCAGGGTCCGCAGCCGAAGAGG	BRAF	ENSG00000157764	-0.108570581224592	[]	[]	0	hSpCas9	negative selection	2736919
140924584	140924607	7	+	27260157	MKN45	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	0.143749245839607	[]	[]	5	hSpCas9	negative selection	2738910
140924699	140924722	7	+	27260157	MKN45	viability	GCCATCTTATAACCGAGAGCCGG	BRAF	ENSG00000157764	0.122974921857299	[]	[]	4	hSpCas9	negative selection	2739467
140924641	140924664	7	-	27260157	MKN45	viability	CGGGCCAGGCTCTGTTCAACGGG	BRAF	ENSG00000157764	1.05966267993725	[]	[]	8	hSpCas9	negative selection	2739852
140924697	140924720	7	-	27260157	MKN45	viability	GGCTCTCGGTTATAAGATGGCGG	BRAF	ENSG00000157764	-1.53923955851703	[]	[]	-9	hSpCas9	negative selection	2758760
140924571	140924594	7	-	27260157	MKN45	viability	GGCTGCGGACCCTGCCATTCCGG	BRAF	ENSG00000157764	1.37493806178225	[]	[]	9	hSpCas9	negative selection	2759736
140850142	140850165	7	-	27260157	MKN45	viability	GCCCTATTGGACAAATTTGGTGG	BRAF	ENSG00000157764	-0.607961603429155	[]	[]	-6	hSpCas9	negative selection	2771429
140834669	140834692	7	+	27260157	MKN45	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.581089139879144	[]	[]	7	hSpCas9	negative selection	2771947
140834720	140834743	7	+	27260157	MKN45	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.128072490114759	[]	[]	0	hSpCas9	negative selection	2797448
140924590	140924613	7	+	27260157	MKN45	viability	AGCCGAAGAGGCCGCGGCGCCGG	BRAF	ENSG00000157764	0.566665754015876	[]	[]	7	hSpCas9	negative selection	2798271
140924672	140924695	7	-	27260157	MKN45	viability	CTGAGCGGTGGCGGTGGTGGCGG	BRAF	ENSG00000157764	-1.19882520401979	[]	[]	-8	hSpCas9	negative selection	2800392
140924557	140924580	7	+	27260157	MKN45	viability	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	0.7478538742138	[]	[]	7	hSpCas9	negative selection	2800931
140924615	140924638	7	-	27260157	RKO	viability	ATGGAGCCCGAGGCCGGCGCCGG	BRAF	ENSG00000157764	0.457761148572399	[]	[]	2	hSpCas9	negative selection	2803402
140850155	140850178	7	-	27260157	RKO	viability	GGAACATATAGAGGCCCTATTGG	BRAF	ENSG00000157764	0.0683339825620338	[]	[]	0	hSpCas9	negative selection	2803842
140924640	140924663	7	-	27260157	RKO	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-1.56635278943531	[]	[]	-9	hSpCas9	negative selection	2804323
140834710	140834733	7	+	27260157	RKO	viability	GAGATGAAGGTAGCACTGAAAGG	BRAF	ENSG00000157764	-0.66391885840524	[]	[]	-7	hSpCas9	negative selection	2805389
140924562	140924585	7	+	27260157	RKO	viability	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-1.10599688245394	[]	[]	-8	hSpCas9	negative selection	2805828
140924568	140924591	7	-	27260157	RKO	viability	TGCGGACCCTGCCATTCCGGAGG	BRAF	ENSG00000157764	-1.31478038757805	[]	[]	-8	hSpCas9	negative selection	2808250
140924684	140924707	7	-	27260157	RKO	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	0.496323436531983	[]	[]	2	hSpCas9	negative selection	2808314
140924642	140924665	7	+	27260157	RKO	viability	CCGTTGAACAGAGCCTGGCCCGG	BRAF	ENSG00000157764	-0.236957642354322	[]	[]	-1	hSpCas9	negative selection	2811707
140924578	140924601	7	+	27260157	RKO	viability	GGCAGGGTCCGCAGCCGAAGAGG	BRAF	ENSG00000157764	-2.1888469779525	[]	[]	-9	hSpCas9	negative selection	2813049
140924584	140924607	7	+	27260157	RKO	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.0137869376840127	[]	[]	0	hSpCas9	negative selection	2815040
140924699	140924722	7	+	27260157	RKO	viability	GCCATCTTATAACCGAGAGCCGG	BRAF	ENSG00000157764	0.601164267595266	[]	[]	3	hSpCas9	negative selection	2815597
140924641	140924664	7	-	27260157	RKO	viability	CGGGCCAGGCTCTGTTCAACGGG	BRAF	ENSG00000157764	-0.112280007423592	[]	[]	0	hSpCas9	negative selection	2815982
140924697	140924720	7	-	27260157	RKO	viability	GGCTCTCGGTTATAAGATGGCGG	BRAF	ENSG00000157764	-1.04175814138783	[]	[]	-8	hSpCas9	negative selection	2834890
140924571	140924594	7	-	27260157	RKO	viability	GGCTGCGGACCCTGCCATTCCGG	BRAF	ENSG00000157764	0.121136739519416	[]	[]	0	hSpCas9	negative selection	2835866
140850142	140850165	7	-	27260157	RKO	viability	GCCCTATTGGACAAATTTGGTGG	BRAF	ENSG00000157764	-0.170882263412781	[]	[]	-1	hSpCas9	negative selection	2847559
140834669	140834692	7	+	27260157	RKO	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.230024901895236	[]	[]	-1	hSpCas9	negative selection	2848077
140834720	140834743	7	+	27260157	RKO	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-1.33957648435987	[]	[]	-8	hSpCas9	negative selection	2873578
140924590	140924613	7	+	27260157	RKO	viability	AGCCGAAGAGGCCGCGGCGCCGG	BRAF	ENSG00000157764	-0.517912011731278	[]	[]	-6	hSpCas9	negative selection	2874401
140924672	140924695	7	-	27260157	RKO	viability	CTGAGCGGTGGCGGTGGTGGCGG	BRAF	ENSG00000157764	-2.01353313854164	[]	[]	-9	hSpCas9	negative selection	2876522
140924557	140924580	7	+	27260157	RKO	viability	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-2.62671536265203	[]	[]	-9	hSpCas9	negative selection	2877061
140924615	140924638	7	-	27260157	SF268	viability	ATGGAGCCCGAGGCCGGCGCCGG	BRAF	ENSG00000157764	1.61305415358772	[]	[]	9	hSpCas9	negative selection	2879532
140850155	140850178	7	-	27260157	SF268	viability	GGAACATATAGAGGCCCTATTGG	BRAF	ENSG00000157764	0.364011334819094	[]	[]	4	hSpCas9	negative selection	2879972
140924640	140924663	7	-	27260157	SF268	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-0.412217173333056	[]	[]	-3	hSpCas9	negative selection	2880453
140834710	140834733	7	+	27260157	SF268	viability	GAGATGAAGGTAGCACTGAAAGG	BRAF	ENSG00000157764	0.172655187800089	[]	[]	0	hSpCas9	negative selection	2881519
140924562	140924585	7	+	27260157	SF268	viability	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.0249658241559647	[]	[]	0	hSpCas9	negative selection	2881958
140924568	140924591	7	-	27260157	SF268	viability	TGCGGACCCTGCCATTCCGGAGG	BRAF	ENSG00000157764	0.380221531394675	[]	[]	4	hSpCas9	negative selection	2884380
140924684	140924707	7	-	27260157	SF268	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	1.23831205695879	[]	[]	9	hSpCas9	negative selection	2884444
140924642	140924665	7	+	27260157	SF268	viability	CCGTTGAACAGAGCCTGGCCCGG	BRAF	ENSG00000157764	0.355956453302377	[]	[]	4	hSpCas9	negative selection	2887837
140924578	140924601	7	+	27260157	SF268	viability	GGCAGGGTCCGCAGCCGAAGAGG	BRAF	ENSG00000157764	-0.755146513002961	[]	[]	-6	hSpCas9	negative selection	2889179
140924584	140924607	7	+	27260157	SF268	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.527616894024084	[]	[]	-4	hSpCas9	negative selection	2891170
140924699	140924722	7	+	27260157	SF268	viability	GCCATCTTATAACCGAGAGCCGG	BRAF	ENSG00000157764	0.204798861632389	[]	[]	3	hSpCas9	negative selection	2891727
140924641	140924664	7	-	27260157	SF268	viability	CGGGCCAGGCTCTGTTCAACGGG	BRAF	ENSG00000157764	1.08195346456524	[]	[]	9	hSpCas9	negative selection	2892112
140924697	140924720	7	-	27260157	SF268	viability	GGCTCTCGGTTATAAGATGGCGG	BRAF	ENSG00000157764	-0.431461475193301	[]	[]	-3	hSpCas9	negative selection	2911020
140924571	140924594	7	-	27260157	SF268	viability	GGCTGCGGACCCTGCCATTCCGG	BRAF	ENSG00000157764	0.809789454103564	[]	[]	8	hSpCas9	negative selection	2911996
140850142	140850165	7	-	27260157	SF268	viability	GCCCTATTGGACAAATTTGGTGG	BRAF	ENSG00000157764	-0.193719460550658	[]	[]	-1	hSpCas9	negative selection	2923689
140834669	140834692	7	+	27260157	SF268	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.910051259791921	[]	[]	9	hSpCas9	negative selection	2924207
140834720	140834743	7	+	27260157	SF268	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.731010134245815	[]	[]	-5	hSpCas9	negative selection	2949708
140924590	140924613	7	+	27260157	SF268	viability	AGCCGAAGAGGCCGCGGCGCCGG	BRAF	ENSG00000157764	0.419610194022653	[]	[]	4	hSpCas9	negative selection	2950531
140924672	140924695	7	-	27260157	SF268	viability	CTGAGCGGTGGCGGTGGTGGCGG	BRAF	ENSG00000157764	-1.60321876308943	[]	[]	-8	hSpCas9	negative selection	2952652
140924557	140924580	7	+	27260157	SF268	viability	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	0.215323740346922	[]	[]	3	hSpCas9	negative selection	2953191
140924552	140924575	7	+	27013184	SW480	treatment with recombinant TRAIL	GCGCCAGCACTCACCTCCTCCGG	BRAF	ENSG00000157764	0.5364590696282867	[246,576]	[251,243]	2	hSpCas9	positive selection	2962468
140924557	140924580	7	+	27013184	SW480	treatment with recombinant TRAIL	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.13397917936737525	[343,497]	[140,193]	0	hSpCas9	positive selection	2962469
140783021	140783044	7	+	27013184	SW480	treatment with recombinant TRAIL	CATTCGATTCCTGTCTTCTGAGG	BRAF	ENSG00000157764	1.2124738110114626	[1,1]	[1,1]	6	hSpCas9	positive selection	2962470
140850140	140850163	7	-	27013184	SW480	treatment with recombinant TRAIL	CCTATTGGACAAATTTGGTGGGG	BRAF	ENSG00000157764	-0.06185865264814766	[167,164]	[65,72]	0	hSpCas9	positive selection	2962471
140924561	140924584	7	+	27013184	SW480	treatment with recombinant TRAIL	CTCACCTCCTCCGGAATGGCAGG	BRAF	ENSG00000157764	2.242634544257135	[621,762]	[1658,1034]	8	hSpCas9	positive selection	2962472
140783049	140783072	7	+	27013184	SW480	treatment with recombinant TRAIL	GATGACTTCCTTTCTCGCTGAGG	BRAF	ENSG00000157764	-0.23546722980766543	[389,556]	[162,181]	-1	hSpCas9	positive selection	2962473
140850141	140850164	7	-	27013184	SW480	treatment with recombinant TRAIL	CCCTATTGGACAAATTTGGTGGG	BRAF	ENSG00000157764	1.4402490853796577	[82,106]	[31,220]	6	hSpCas9	positive selection	2962474
140850142	140850165	7	-	27013184	SW480	treatment with recombinant TRAIL	GCCCTATTGGACAAATTTGGTGG	BRAF	ENSG00000157764	-0.4651081895255332	[147,211]	[42,72]	-2	hSpCas9	positive selection	2962475
140850145	140850168	7	-	27013184	SW480	treatment with recombinant TRAIL	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	1.2286000927461977	[429,448]	[391,516]	6	hSpCas9	positive selection	2962476
140850155	140850178	7	-	27013184	SW480	treatment with recombinant TRAIL	GGAACATATAGAGGCCCTATTGG	BRAF	ENSG00000157764	3.515788720916181	[23,14]	[129,52]	9	hSpCas9	positive selection	2962477
140850176	140850199	7	-	27013184	SW480	treatment with recombinant TRAIL	ACAAATGATTAAGTTGACACAGG	BRAF	ENSG00000157764	0.6062720988084191	[174,74]	[18,178]	3	hSpCas9	positive selection	2962478
140924562	140924585	7	+	27013184	SW480	treatment with recombinant TRAIL	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	0.8414897233914582	[426,768]	[467,425]	4	hSpCas9	positive selection	2962479
140754178	140754201	7	+	27013184	SW480	treatment with recombinant TRAIL	GAAGGATACTATTACTCTTGAGG	BRAF	ENSG00000157764	0.5337725008455207	[244,327]	[186,161]	2	hSpCas9	positive selection	2962480
140754187	140754210	7	+	27013184	SW480	treatment with recombinant TRAIL	TATTACTCTTGAGGTCTCTGTGG	BRAF	ENSG00000157764	0.6780207473409552	[340,161]	[122,258]	3	hSpCas9	positive selection	2962482
140754200	140754223	7	+	27013184	SW480	treatment with recombinant TRAIL	GTCTCTGTGGATGATTGACTTGG	BRAF	ENSG00000157764	2.1990271846812486	[157,215]	[383,338]	8	hSpCas9	positive selection	2962483
140924637	140924660	7	+	27013184	SW480	treatment with recombinant TRAIL	TGTCCCCGTTGAACAGAGCCTGG	BRAF	ENSG00000157764	-2.613577183605639	[1296,1491]	[67,139]	-8	hSpCas9	positive selection	2962484
140783094	140783117	7	+	27013184	SW480	treatment with recombinant TRAIL	TTCACGTTAGTTAGTGAGCCAGG	BRAF	ENSG00000157764	-0.43143120106495236	[87,49]	[34,4]	-2	hSpCas9	positive selection	2962485
140924642	140924665	7	+	27013184	SW480	treatment with recombinant TRAIL	CCGTTGAACAGAGCCTGGCCCGG	BRAF	ENSG00000157764	2.2618156322184357	[103,71]	[156,224]	8	hSpCas9	positive selection	2962486
140783106	140783129	7	+	27013184	SW480	treatment with recombinant TRAIL	AGTGAGCCAGGTAATGAGGCAGG	BRAF	ENSG00000157764	-1.3429893270743993	[42,32]	[1,12]	-6	hSpCas9	positive selection	2962487
140783073	140783096	7	-	27013184	SW480	treatment with recombinant TRAIL	AAAGCCTTACAGAAATCTCCAGG	BRAF	ENSG00000157764	-1.2150759026446059	[79,157]	[18,24]	-5	hSpCas9	positive selection	2962489
140924699	140924722	7	+	27013184	SW480	treatment with recombinant TRAIL	GCCATCTTATAACCGAGAGCCGG	BRAF	ENSG00000157764	-1.1874565026380999	[81,257]	[19,45]	-5	hSpCas9	positive selection	2962490
140783107	140783130	7	+	27013184	SW480	treatment with recombinant TRAIL	GTGAGCCAGGTAATGAGGCAGGG	BRAF	ENSG00000157764	-3.0116320423096417	[133,141]	[1,14]	-8	hSpCas9	positive selection	2962491
140783112	140783135	7	-	27013184	SW480	treatment with recombinant TRAIL	ACCCCCCCTGCCTCATTACCTGG	BRAF	ENSG00000157764	-0.8675396911471773	[952,1160]	[227,275]	-4	hSpCas9	positive selection	2962492
140783145	140783168	7	-	27013184	SW480	treatment with recombinant TRAIL	ACTAATTTAGGATCAACCACAGG	BRAF	ENSG00000157764	-1.6007987839045723	[40,70]	[1,15]	-6	hSpCas9	positive selection	2962493
140850140	140850163	7	+	27013184	SW480	treatment with recombinant TRAIL	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	-2.876789655478471	[277,500]	[18,26]	-8	hSpCas9	positive selection	2962494
140924700	140924723	7	+	27013184	SW480	treatment with recombinant TRAIL	CCATCTTATAACCGAGAGCCGGG	BRAF	ENSG00000157764	-0.897488468292861	[356,305]	[66,91]	-4	hSpCas9	positive selection	2962495
140783108	140783131	7	+	27013184	SW480	treatment with recombinant TRAIL	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	1.5742648002666089	[117,444]	[203,540]	7	hSpCas9	positive selection	2962496
140850141	140850164	7	+	27013184	SW480	treatment with recombinant TRAIL	CCCACCAAATTTGTCCAATAGGG	BRAF	ENSG00000157764	-5.572054021599312	[168,281]	[1,1]	-9	hSpCas9	positive selection	2962497
140924701	140924724	7	+	27013184	SW480	treatment with recombinant TRAIL	CATCTTATAACCGAGAGCCGGGG	BRAF	ENSG00000157764	0.10789135247956727	[48,32]	[25,9]	0	hSpCas9	positive selection	2962498
140783129	140783152	7	+	27013184	SW480	treatment with recombinant TRAIL	GGGGGTAGCAGACAAACCTGTGG	BRAF	ENSG00000157764	-3.306611254896035	[28,65]	[1,1]	-9	hSpCas9	positive selection	2962499
140800359	140800382	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.3626043078062428	[4,4]	[3,1]	-5	hSpCas9	positive selection	2973636
140924640	140924663	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	0.6473356278645863	[1,2]	[2,2]	9	hSpCas9	positive selection	2973637
140924585	140924608	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.2291241355350771	[2,2]	[3,0]	-3	hSpCas9	positive selection	2973638
140834615	140834638	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-0.23933755321042052	[2,3]	[2,1]	-3	hSpCas9	positive selection	2973639
140800359	140800382	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.025244339924956505	[4,4]	[3,2]	0	hSpCas9	positive selection	3041494
140924640	140924663	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	0.26252419110735314	[1,1]	[1,0]	4	hSpCas9	positive selection	3041495
140924585	140924608	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	0.12392106548883758	[2,2]	[2,1]	2	hSpCas9	positive selection	3041496
140834615	140834638	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-0.2609332180702416	[2,2]	[1,1]	-4	hSpCas9	positive selection	3041497
140850106	140850129		+	24336571	A375	resistance to PLX after 7 days	CTTACCTCCAGATATATTGATGG	BRAF	ENSG00000157764	-0.14570706376062648	[7,4]	[5,5]	-5	hSpCas9	positive selection	3150579
140850145	140850168		-	24336571	A375	resistance to PLX after 7 days	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	-0.17485824336420097	[6,6]	[6,4]	-5	hSpCas9	positive selection	3150590
140834669	140834692		+	24336571	A375	resistance to PLX after 7 days	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.17372804226000232	[9,7]	[9,10]	5	hSpCas9	positive selection	3150599
140850106	140850129		+	24336571	A375	resistance to PLX after 14 days	CTTACCTCCAGATATATTGATGG	BRAF	ENSG00000157764	0.0057306472760535465	[6,5]	[2,2]	0	hSpCas9	positive selection	3208372
140850145	140850168		-	24336571	A375	resistance to PLX after 14 days	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	-0.22221339636408755	[7,7]	[2,2]	-2	hSpCas9	positive selection	3208383
140834669	140834692		+	24336571	A375	resistance to PLX after 14 days	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.11655248586953793	[4,4]	[2,1]	1	hSpCas9	positive selection	3208392
140850106	140850129		+	24336571	A375	viability after 7 days	CTTACCTCCAGATATATTGATGG	BRAF	ENSG00000157764	-0.4235864269683147	[8]	[7,4]	-6	hSpCas9	negative selection	3266165
140850145	140850168		-	24336571	A375	viability after 7 days	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.18224460322802427	[5]	[6,6]	2	hSpCas9	negative selection	3266176
140834669	140834692		+	24336571	A375	viability after 7 days	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.5095965981989475	[13]	[9,7]	-6	hSpCas9	negative selection	3266185
140850106	140850129		+	24336571	A375	viability after 14 days	CTTACCTCCAGATATATTGATGG	BRAF	ENSG00000157764	-0.3907896613637898	[8]	[6,5]	-5	hSpCas9	negative selection	3323958
140850145	140850168		-	24336571	A375	viability after 14 days	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.41483316328641584	[5]	[7,7]	5	hSpCas9	negative selection	3323969
140834669	140834692		+	24336571	A375	viability after 14 days	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-1.2860854698730033	[13]	[4,4]	-9	hSpCas9	negative selection	3323978
140850140	140850163	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	-0.7480047863487262	[248,264]	[0,0]	-5	hSpCas9	positive selection	3339039
140850145	140850168	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	1.3041949014011514	[54,68]	[0,0]	5	hSpCas9	positive selection	3339040
140834669	140834692	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.10859591305289965	[157,171]	[0,0]	0	hSpCas9	positive selection	3339041
140808947	140808970	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	-1.1773020161908894	[345,345]	[0,0]	-7	hSpCas9	positive selection	3358283
140808984	140809007	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-1.0825237914387897	[323,323]	[0,0]	-7	hSpCas9	positive selection	3358284
140834720	140834743	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.38696149186243056	[116,116]	[0,0]	2	hSpCas9	positive selection	3358285
140800358	140800381	7	+	26780180	HT29	viability (Avana library 4 designs)	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	2.81770978681038	[]	[]	8	hSpCas9	negative selection	3409833
140924640	140924663	7	-	26780180	HT29	viability (Avana library 4 designs)	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	4.83571092528688	[]	[]	9	hSpCas9	negative selection	3409834
140924584	140924607	7	+	26780180	HT29	viability (Avana library 4 designs)	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	4.27096349782508	[]	[]	9	hSpCas9	negative selection	3409835
140834615	140834638	7	-	26780180	HT29	viability (Avana library 4 designs)	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	3.65441968655762	[]	[]	9	hSpCas9	negative selection	3409836
140834615	140834638	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-14.626350655181	[]	[]	-9	hSpCas9	negative selection	3484041
140924584	140924607	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-6.36182201529309	[]	[]	-6	hSpCas9	negative selection	3484042
140924640	140924663	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-15.9799300863807	[]	[]	-9	hSpCas9	negative selection	3484043
140800358	140800381	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-5.94403102052553	[]	[]	-6	hSpCas9	negative selection	3484044
140801473	140801496	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATAACCACATGTTTGACAGCGG	BRAF	ENSG00000157764	-5.77157854184134	[]	[]	-6	hSpCas9	negative selection	3484045
140808030	140808053	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATATCAGTGTCCCAACCAATTGG	BRAF	ENSG00000157764	-4.14398234227183	[]	[]	-5	hSpCas9	negative selection	3484046
140834615	140834638	7	-	26780180	A375	viability (Avana lentiGuide)	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	24.9043414468616	[]	[]	9	hSpCas9	negative selection	3592700
140924584	140924607	7	+	26780180	A375	viability (Avana lentiGuide)	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	32.73159298576	[]	[]	9	hSpCas9	negative selection	3592701
140924640	140924663	7	-	26780180	A375	viability (Avana lentiGuide)	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	24.3446435826377	[]	[]	9	hSpCas9	negative selection	3592702
140800358	140800381	7	+	26780180	A375	viability (Avana lentiGuide)	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	14.6068178929201	[]	[]	8	hSpCas9	negative selection	3592703
140801473	140801496	7	+	26780180	A375	viability (Avana lentiGuide)	TATAACCACATGTTTGACAGCGG	BRAF	ENSG00000157764	19.6104611467522	[]	[]	8	hSpCas9	negative selection	3592704
140808030	140808053	7	+	26780180	A375	viability (Avana lentiGuide)	ATATCAGTGTCCCAACCAATTGG	BRAF	ENSG00000157764	16.7316931526896	[]	[]	8	hSpCas9	negative selection	3592705
140834615	140834638	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-0.816693355937609	[4]	[1,2]	-8	hSpCas9	positive selection	3701359
140924584	140924607	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.24797597471421362	[5]	[3,4]	-4	hSpCas9	positive selection	3701360
140924640	140924663	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-0.6621758174194681	[4]	[1,2]	-7	hSpCas9	positive selection	3701361
140800358	140800381	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.3321197520221324	[6]	[4,4]	-5	hSpCas9	positive selection	3701362
140801473	140801496	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATAACCACATGTTTGACAGCGG	BRAF	ENSG00000157764	-0.21643284983709643	[7]	[5,5]	-3	hSpCas9	positive selection	3701363
140808030	140808053	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATATCAGTGTCCCAACCAATTGG	BRAF	ENSG00000157764	-0.2882880963021024	[5]	[4,3]	-4	hSpCas9	positive selection	3701364
140834615	140834638	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	0.3413393400730225	[5]	[7,4]	8	hSpCas9	positive selection	3809966
140924584	140924607	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-1.9764114827834123	[5]	[0,0]	-9	hSpCas9	positive selection	3809967
140924640	140924663	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-1.7636153972942383	[5]	[1,0]	-9	hSpCas9	positive selection	3809968
140800358	140800381	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.407361207357393	[6]	[3,3]	-5	hSpCas9	positive selection	3809969
140801473	140801496	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATAACCACATGTTTGACAGCGG	BRAF	ENSG00000157764	-0.2063620281662868	[6]	[4,4]	-3	hSpCas9	positive selection	3809970
140808030	140808053	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATATCAGTGTCCCAACCAATTGG	BRAF	ENSG00000157764	-0.050554323278283714	[5]	[4,3]	0	hSpCas9	positive selection	3809971
140850140	140850163	7	+	26780180	A375	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.41347537631412	[]	[]	1	hSpCas9	negative selection	3918222
140850145	140850168	7	-	26780180	A375	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	1.30598502754881	[]	[]	7	hSpCas9	negative selection	3918223
140808947	140808970	7	+	26780180	A375	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	1.36077186146108	[]	[]	7	hSpCas9	negative selection	3918224
140834669	140834692	7	+	26780180	A375	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	1.16484258190953	[]	[]	6	hSpCas9	negative selection	3918225
140834720	140834743	7	+	26780180	A375	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	2.20021423010663	[]	[]	9	hSpCas9	negative selection	3918226
140808984	140809007	7	-	26780180	A375	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	2.2858180304882	[]	[]	9	hSpCas9	negative selection	3918227
140850140	140850163	7	+	26780180	HT29	viability (GeCKOv2 library)	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.11953938281207	[]	[]	0	hSpCas9	negative selection	4026188
140850145	140850168	7	-	26780180	HT29	viability (GeCKOv2 library)	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.630024137490548	[]	[]	2	hSpCas9	negative selection	4026189
140808947	140808970	7	+	26780180	HT29	viability (GeCKOv2 library)	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	2.0388483174509	[]	[]	9	hSpCas9	negative selection	4026190
140834669	140834692	7	+	26780180	HT29	viability (GeCKOv2 library)	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	2.03925922942029	[]	[]	9	hSpCas9	negative selection	4026191
140834720	140834743	7	+	26780180	HT29	viability (GeCKOv2 library)	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	2.75657892747917	[]	[]	9	hSpCas9	negative selection	4026192
140808984	140809007	7	-	26780180	HT29	viability (GeCKOv2 library)	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	3.33654721317185	[]	[]	9	hSpCas9	negative selection	4026193
140850106	140850129	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTACCTCCAGATATATTGATGG	BRAF	ENSG00000157764	-0.4186627580258883	[2]	[0,1]	-8	hSpCas9	positive selection	4176990
140850145	140850168	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.07809528039548086	[2]	[2,1]	2	hSpCas9	positive selection	4177001
140834669	140834692	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.5152806205471822	[3]	[2,0]	-8	hSpCas9	positive selection	4177012
140850106	140850129	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTACCTCCAGATATATTGATGG	BRAF	ENSG00000157764	-0.28313714185809147	[2]	[0,0,1,0]	-4	hSpCas9	positive selection	4241012
140850145	140850168	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	1.7183130833109002	[2]	[3,3,4,3]	9	hSpCas9	positive selection	4241023
140834669	140834692	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.7262491003878262	[3]	[0,0,0,3]	5	hSpCas9	positive selection	4241034
140850140	140850163	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.52413636592767	[3]	[3,3]	9	hSpCas9	positive selection	4258453
140850145	140850168	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.05545142809581893	[2]	[2,0]	1	hSpCas9	positive selection	4258454
140834669	140834692	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.045110229617187525	[3]	[3,1]	0	hSpCas9	positive selection	4258455
140808947	140808970	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	-0.5404935936460277	[3]	[2,0]	-8	hSpCas9	positive selection	4322737
140808984	140809007	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.6284511581078878	[4]	[2,0]	-8	hSpCas9	positive selection	4322738
140834720	140834743	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.8240559886202763	[3]	[2,0]	-9	hSpCas9	positive selection	4322739
140800356	140800378	7	+	27760321	OCIAML3	viability	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	0.20905142008985966	[844,636]	[679,643]	2	hSpCas9	negative selection	4382174
140801399	140801421	7	+	27760321	OCIAML3	viability	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	-0.7820398281845176	[56,39]	[13,31]	-6	hSpCas9	negative selection	4382175
140801444	140801466	7	+	27760321	OCIAML3	viability	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.8481795407235109	[858,813]	[345,386]	-7	hSpCas9	negative selection	4382176
140834629	140834651	7	+	27760321	OCIAML3	viability	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4382177
140850141	140850163	7	+	27760321	OCIAML3	viability	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.2607088378410384	[366,294]	[254,377]	3	hSpCas9	negative selection	4382178
140800356	140800378	7	+	27760321	OCIAML2	viability	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	0.43585911609105	[844,636]	[754,868]	6	hSpCas9	negative selection	4465637
140801399	140801421	7	+	27760321	OCIAML2	viability	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	-0.5752110293660091	[56,39]	[19,33]	-6	hSpCas9	negative selection	4465638
140801444	140801466	7	+	27760321	OCIAML2	viability	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.051046485687266996	[858,813]	[567,766]	0	hSpCas9	negative selection	4465639
140834629	140834651	7	+	27760321	OCIAML2	viability	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4465640
140850141	140850163	7	+	27760321	OCIAML2	viability	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.8267111311336586	[366,294]	[353,627]	9	hSpCas9	negative selection	4465641
140800356	140800378	7	+	27760321	MV411	viability	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	0.8846827905872855	[844,636]	[904,880]	6	hSpCas9	negative selection	4549100
140801399	140801421	7	+	27760321	MV411	viability	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	-2.663156630230035	[56,39]	[0,10]	-9	hSpCas9	negative selection	4549101
140801444	140801466	7	+	27760321	MV411	viability	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.8529649487972969	[858,813]	[239,404]	-5	hSpCas9	negative selection	4549102
140834629	140834651	7	+	27760321	MV411	viability	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	0.5949485011219959	[0,0]	[0,0]	4	hSpCas9	negative selection	4549103
140850141	140850163	7	+	27760321	MV411	viability	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	1.084907379476877	[366,294]	[365,602]	7	hSpCas9	negative selection	4549104
140800356	140800378	7	+	27760321	HL60	viability	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	-0.006516003690681171	[844,636]	[617,575]	0	hSpCas9	negative selection	4632563
140801399	140801421	7	+	27760321	HL60	viability	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	-1.7211891513072555	[56,39]	[7,15]	-9	hSpCas9	negative selection	4632564
140801444	140801466	7	+	27760321	HL60	viability	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.8993158714774159	[858,813]	[258,480]	-7	hSpCas9	negative selection	4632565
140834629	140834651	7	+	27760321	HL60	viability	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4632566
140850141	140850163	7	+	27760321	HL60	viability	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.060465357579540524	[366,294]	[275,284]	0	hSpCas9	negative selection	4632567
140800356	140800378	7	+	27760321	HT1080	viability	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	-0.6994066645460392	[636,496]	[98,182]	-3	hSpCas9	negative selection	4716026
140801399	140801421	7	+	27760321	HT1080	viability	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	-1.5526243851669794	[39,30]	[0,8]	-5	hSpCas9	negative selection	4716027
140801444	140801466	7	+	27760321	HT1080	viability	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-3.748238805666989	[813,634]	[20,21]	-8	hSpCas9	negative selection	4716028
140834629	140834651	7	+	27760321	HT1080	viability	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4716029
140850141	140850163	7	+	27760321	HT1080	viability	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.916132763952817	[294,229]	[182,212]	5	hSpCas9	negative selection	4716030
140800356	140800378	7	+	27760321	HT29	viability after 7 days	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	0.16972320882950231	[636,496]	[705,1121,620]	2	hSpCas9	negative selection	4799489
140801399	140801421	7	+	27760321	HT29	viability after 7 days	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	-0.6281341990657228	[39,30]	[7,1,73]	-7	hSpCas9	negative selection	4799490
140801444	140801466	7	+	27760321	HT29	viability after 7 days	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-2.6847970682475335	[813,634]	[111,86,227]	-9	hSpCas9	negative selection	4799491
140834629	140834651	7	+	27760321	HT29	viability after 7 days	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4799492
140850141	140850163	7	+	27760321	HT29	viability after 7 days	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	1.023566975763938	[294,229]	[829,696,554]	9	hSpCas9	negative selection	4799493
140800356	140800378	7	+	27760321	HT29	viability after 25 days	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	-0.13184692578039536	[636,496]	[493,610,683]	-1	hSpCas9	negative selection	4882952
140801399	140801421	7	+	27760321	HT29	viability after 25 days	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	-1.6707019370510614	[39,30]	[0,15,22]	-7	hSpCas9	negative selection	4882953
140801444	140801466	7	+	27760321	HT29	viability after 25 days	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-7.803734229375059	[813,634]	[0,8,0]	-9	hSpCas9	negative selection	4882954
140834629	140834651	7	+	27760321	HT29	viability after 25 days	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4882955
140850141	140850163	7	+	27760321	HT29	viability after 25 days	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	1.1099295542702874	[294,229]	[565,719,661]	9	hSpCas9	negative selection	4882956
140800356	140800378	7	+	27760321	HT29	viability after 22 days	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	-0.023799152889443675	[636,496]	[849,606,469]	0	hSpCas9	negative selection	4966415
140801399	140801421	7	+	27760321	HT29	viability after 22 days	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	-0.7538184561289358	[39,30]	[56,0,13]	-6	hSpCas9	negative selection	4966416
140801444	140801466	7	+	27760321	HT29	viability after 22 days	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-5.179391185338608	[813,634]	[0,38,29]	-9	hSpCas9	negative selection	4966417
140834629	140834651	7	+	27760321	HT29	viability after 22 days	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4966418
140850141	140850163	7	+	27760321	HT29	viability after 22 days	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.8574390934842049	[294,229]	[692,450,500]	8	hSpCas9	negative selection	4966419
140800356	140800378	7	+	27760321	HT29	viability after 19 days	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	0.17034940783069985	[636,496]	[564,489,1101]	1	hSpCas9	negative selection	5049878
140801399	140801421	7	+	27760321	HT29	viability after 19 days	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	-5.342463743924357	[39,30]	[0,0,0]	-9	hSpCas9	negative selection	5049879
140801444	140801466	7	+	27760321	HT29	viability after 19 days	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-7.165195441920618	[813,634]	[0,14,0]	-9	hSpCas9	negative selection	5049880
140834629	140834651	7	+	27760321	HT29	viability after 19 days	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5049881
140850141	140850163	7	+	27760321	HT29	viability after 19 days	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.8958604972239361	[294,229]	[534,742,400]	8	hSpCas9	negative selection	5049882
140800356	140800378	7	+	27760321	HT29	viability after 16 days	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	-0.5285585400701031	[636,496]	[280,447,574]	-5	hSpCas9	negative selection	5133341
140801399	140801421	7	+	27760321	HT29	viability after 16 days	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	-3.6500833575278917	[39,30]	[7,0,0]	-9	hSpCas9	negative selection	5133342
140801444	140801466	7	+	27760321	HT29	viability after 16 days	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-4.8953899241702485	[813,634]	[0,73,2]	-9	hSpCas9	negative selection	5133343
140834629	140834651	7	+	27760321	HT29	viability after 16 days	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5133344
140850141	140850163	7	+	27760321	HT29	viability after 16 days	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	1.0586315515576306	[294,229]	[708,656,476]	9	hSpCas9	negative selection	5133345
140800356	140800378	7	+	27760321	HT29	viability after 13 days	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	-0.35689024545674	[636,496]	[292,678,565]	-4	hSpCas9	negative selection	5216804
140801399	140801421	7	+	27760321	HT29	viability after 13 days	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	-0.8753382894451547	[39,30]	[8,46,11]	-7	hSpCas9	negative selection	5216805
140801444	140801466	7	+	27760321	HT29	viability after 13 days	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-3.8187276898559865	[813,634]	[66,91,21]	-9	hSpCas9	negative selection	5216806
140834629	140834651	7	+	27760321	HT29	viability after 13 days	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5216807
140850141	140850163	7	+	27760321	HT29	viability after 13 days	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	1.290256829269393	[294,229]	[995,739,511]	9	hSpCas9	negative selection	5216808
140800356	140800378	7	+	27760321	HT29	viability after 10 days	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	-0.36427830234302155	[636,496]	[551,633,467]	-5	hSpCas9	negative selection	5300267
140801399	140801421	7	+	27760321	HT29	viability after 10 days	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	-2.564420296802892	[39,30]	[0,0,19]	-9	hSpCas9	negative selection	5300268
140801444	140801466	7	+	27760321	HT29	viability after 10 days	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-2.669016956247445	[813,634]	[157,101,164]	-9	hSpCas9	negative selection	5300269
140834629	140834651	7	+	27760321	HT29	viability after 10 days	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5300270
140850141	140850163	7	+	27760321	HT29	viability after 10 days	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	1.1397736978976625	[294,229]	[757,860,554]	9	hSpCas9	negative selection	5300271
140800356	140800378	7	+	27760321	MOLM13	viability	CCATACCCAATAGAGTCCGAGG	BRAF	ENSG00000157764	0.6771465252511609	[844,636]	[1086,301]	5	hSpCas9	negative selection	5383730
140801399	140801421	7	+	27760321	MOLM13	viability	TTGGATTACTTACTCAAGTTGG	BRAF	ENSG00000157764	2.3621204420882513	[56,39]	[2,254]	9	hSpCas9	negative selection	5383731
140801444	140801466	7	+	27760321	MOLM13	viability	AACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	1.0248791185740735	[858,813]	[189,1617]	7	hSpCas9	negative selection	5383732
140834629	140834651	7	+	27760321	MOLM13	viability	GCAGGAAGACTCTAACGATAGG	BRAF	ENSG00000157764	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5383733
140850141	140850163	7	+	27760321	MOLM13	viability	CCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.692717559009264	[366,294]	[156,421]	5	hSpCas9	negative selection	5383734
140924699	140924722	7	+	27661255	K562	viability	GCCATCTTATAACCGAGAGCCGG	BRAF	ENSG00000157764	0.2675642251125341	[86,145]	[110,110]	8	dCas9-KRAB	negative selection	5465458
140850140	140850163	7	+	27260156	BXPC3	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.5801655534870658	[607]	[800,1050,913,1050]	9	hSpCas9	negative selection	5530913
140850145	140850168	7	-	27260156	BXPC3	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.06899850123963946	[232]	[280,166,254,328]	1	hSpCas9	negative selection	5530914
140834669	140834692	7	+	27260156	BXPC3	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.15280304110349174	[554]	[771,625,556,600]	3	hSpCas9	negative selection	5530915
140808947	140808970	7	+	27260156	BXPC3	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.1898088583343756	[571]	[604,733,564,842]	4	hSpCas9	negative selection	5595197
140808984	140809007	7	-	27260156	BXPC3	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.6382895201564133	[1036]	[600,761,733,690]	-8	hSpCas9	negative selection	5595198
140834720	140834743	7	+	27260156	BXPC3	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.5585619360295716	[525]	[304,365,434,396]	-8	hSpCas9	negative selection	5595199
140850140	140850163	7	+	27260156	A673	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.3850606199064026	[607]	[1049,840,782,1164]	8	hSpCas9	negative selection	5652164
140850145	140850168	7	-	27260156	A673	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	-0.20803571086321715	[232]	[214,234,244,271]	-5	hSpCas9	negative selection	5652165
140834669	140834692	7	+	27260156	A673	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.19487446978325787	[554]	[578,534,588,627]	-5	hSpCas9	negative selection	5652166
140808947	140808970	7	+	27260156	A673	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.027655621530865038	[571]	[857,661,659,634]	0	hSpCas9	negative selection	5716448
140808984	140809007	7	-	27260156	A673	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.977118686870595	[1036]	[774,562,556,653]	-9	hSpCas9	negative selection	5716449
140834720	140834743	7	+	27260156	A673	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.6312038407403591	[525]	[427,366,422,415]	-9	hSpCas9	negative selection	5716450
140850140	140850163	7	+	27260156	A375	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.8263964882754529	[607]	[1074,1204,1749,1021]	9	hSpCas9	negative selection	5773415
140850145	140850168	7	-	27260156	A375	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	-0.04793234446525596	[232]	[156,494,265,175]	0	hSpCas9	negative selection	5773416
140834669	140834692	7	+	27260156	A375	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.6744867956044818	[554]	[475,451,351,355]	-7	hSpCas9	negative selection	5773417
140808947	140808970	7	+	27260156	A375	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	-0.4781176349846086	[571]	[426,735,420,379]	-6	hSpCas9	negative selection	5837699
140808984	140809007	7	-	27260156	A375	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-1.7325899151464061	[1036]	[376,581,303,238]	-9	hSpCas9	negative selection	5837700
140834720	140834743	7	+	27260156	A375	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-3.086020941742677	[525]	[87,68,116,20]	-9	hSpCas9	negative selection	5837701
140850140	140850163	7	+	27260156	COLO741	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.5626698971936303	[607]	[1257,1157,1040]	9	hSpCas9	negative selection	5894666
140850145	140850168	7	-	27260156	COLO741	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.12893633977979269	[232]	[229,356,376]	2	hSpCas9	negative selection	5894667
140834669	140834692	7	+	27260156	COLO741	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.1950743134638336	[554]	[792,621,467]	-4	hSpCas9	negative selection	5894668
140808947	140808970	7	+	27260156	COLO741	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.033199250179666906	[571]	[796,812,643]	0	hSpCas9	negative selection	5958950
140808984	140809007	7	-	27260156	COLO741	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-1.2435593708286747	[1036]	[587,659,440]	-9	hSpCas9	negative selection	5958951
140834720	140834743	7	+	27260156	COLO741	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.9663282458010447	[525]	[282,341,396]	-9	hSpCas9	negative selection	5958952
140850140	140850163	7	+	27260156	CAL120	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.4385650567347995	[607]	[1428,714,992]	6	hSpCas9	negative selection	6015917
140850145	140850168	7	-	27260156	CAL120	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.4063887741336325	[232]	[567,321,291]	6	hSpCas9	negative selection	6015918
140834669	140834692	7	+	27260156	CAL120	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.3668608156577543	[554]	[1018,570,1096]	5	hSpCas9	negative selection	6015919
140808947	140808970	7	+	27260156	CAL120	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.520710485193342	[571]	[1094,1001,977]	7	hSpCas9	negative selection	6080201
140808984	140809007	7	-	27260156	CAL120	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.681627030030735	[1036]	[826,748,839]	-7	hSpCas9	negative selection	6080202
140834720	140834743	7	+	27260156	CAL120	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.34622273962386546	[525]	[538,432,574]	-5	hSpCas9	negative selection	6080203
140850140	140850163	7	+	27260156	CADOES1	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.7408021597684262	[607]	[1131,704,1044,894]	9	hSpCas9	negative selection	6137168
140850145	140850168	7	-	27260156	CADOES1	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.27133253893037157	[232]	[209,354,232,247]	4	hSpCas9	negative selection	6137169
140834669	140834692	7	+	27260156	CADOES1	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.32634490038984787	[554]	[501,685,683,719]	5	hSpCas9	negative selection	6137170
140808947	140808970	7	+	27260156	CADOES1	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.5672475542335713	[571]	[712,547,940,956]	8	hSpCas9	negative selection	6201452
140808984	140809007	7	-	27260156	CADOES1	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.48431994645292376	[1036]	[666,734,612,744]	-7	hSpCas9	negative selection	6201453
140834720	140834743	7	+	27260156	CADOES1	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.20353869826303653	[525]	[463,463,431,335]	-4	hSpCas9	negative selection	6201454
140850140	140850163	7	+	27260156	EWS502	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.7071127342341756	[607]	[927,895,1120,1295]	9	hSpCas9	negative selection	6258419
140850145	140850168	7	-	27260156	EWS502	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.33682781866795886	[232]	[305,423,295,207]	6	hSpCas9	negative selection	6258420
140834669	140834692	7	+	27260156	EWS502	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.06291090336746202	[554]	[595,559,724,575]	1	hSpCas9	negative selection	6258421
140808947	140808970	7	+	27260156	EWS502	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.6239932553406469	[571]	[871,986,760,1127]	9	hSpCas9	negative selection	6322703
140808984	140809007	7	-	27260156	EWS502	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.5021359223759361	[1036]	[839,690,849,709]	-7	hSpCas9	negative selection	6322704
140834720	140834743	7	+	27260156	EWS502	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.31140748532014545	[525]	[348,493,469,494]	-5	hSpCas9	negative selection	6322705
140850140	140850163	7	+	27260156	EW8	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.5506295523557694	[607]	[834,742,617,718]	8	hSpCas9	negative selection	6379670
140850145	140850168	7	-	27260156	EW8	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.09407862671559797	[232]	[217,171,196,220]	1	hSpCas9	negative selection	6379671
140834669	140834692	7	+	27260156	EW8	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.19016713403610902	[554]	[597,549,428,497]	3	hSpCas9	negative selection	6379672
140808947	140808970	7	+	27260156	EW8	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.6563645661830664	[571]	[738,875,504,839]	9	hSpCas9	negative selection	6443954
140808984	140809007	7	-	27260156	EW8	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.5747747580577554	[1036]	[585,568,604,490]	-8	hSpCas9	negative selection	6443955
140834720	140834743	7	+	27260156	EW8	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.28980421858348954	[525]	[882,329,402,525]	5	hSpCas9	negative selection	6443956
140850140	140850163	7	+	27260156	CORL105	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.7872751177464892	[607]	[1137,1143,1584,1100]	9	hSpCas9	negative selection	6500921
140850145	140850168	7	-	27260156	CORL105	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.10279540568343126	[232]	[221,320,352,281]	2	hSpCas9	negative selection	6500922
140834669	140834692	7	+	27260156	CORL105	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.2272081212217213	[554]	[611,773,847,815]	4	hSpCas9	negative selection	6500923
140808947	140808970	7	+	27260156	CORL105	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.48682589132492277	[571]	[1114,777,878,980]	8	hSpCas9	negative selection	6565205
140808984	140809007	7	-	27260156	CORL105	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.3608140118238846	[1036]	[1005,865,965,949]	-6	hSpCas9	negative selection	6565206
140834720	140834743	7	+	27260156	CORL105	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.2306253036629239	[525]	[550,521,567,465]	-4	hSpCas9	negative selection	6565207
140850140	140850163	7	+	27260156	HS294T	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.7701299497137271	[607]	[355,498,288,470]	8	hSpCas9	negative selection	6622172
140850145	140850168	7	-	27260156	HS294T	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.13386110812524354	[232]	[68,122,106,97]	1	hSpCas9	negative selection	6622173
140834669	140834692	7	+	27260156	HS294T	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.4037252701145887	[554]	[115,169,196,170]	-5	hSpCas9	negative selection	6622174
140808947	140808970	7	+	27260156	HS294T	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	-0.2837985177015602	[571]	[186,174,190,170]	-4	hSpCas9	negative selection	6686456
140808984	140809007	7	-	27260156	HS294T	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.5339765353183533	[1036]	[161,367,241,355]	-6	hSpCas9	negative selection	6686457
140834720	140834743	7	+	27260156	HS294T	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.9069904856193756	[525]	[86,88,107,160]	-8	hSpCas9	negative selection	6686458
140850140	140850163	7	+	27260156	HCC44	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.3985669022483995	[607]	[1017,540,1168,994]	6	hSpCas9	negative selection	6743423
140850145	140850168	7	-	27260156	HCC44	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.20774769706675056	[232]	[379,294,258,281]	3	hSpCas9	negative selection	6743424
140834669	140834692	7	+	27260156	HCC44	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.24182280228040254	[554]	[892,621,937,579]	4	hSpCas9	negative selection	6743425
140808947	140808970	7	+	27260156	HCC44	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.640471142141497	[571]	[1010,1014,1116,903]	9	hSpCas9	negative selection	6807707
140808984	140809007	7	-	27260156	HCC44	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.41701219493632724	[1036]	[822,746,848,1088]	-6	hSpCas9	negative selection	6807708
140834720	140834743	7	+	27260156	HCC44	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.33455823273990803	[525]	[431,337,623,528]	-5	hSpCas9	negative selection	6807709
140850140	140850163	7	+	27260156	G402	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.9210536866694852	[607]	[1502,1250,1760,1117]	9	hSpCas9	negative selection	6864674
140850145	140850168	7	-	27260156	G402	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.03370452408328173	[232]	[435,152,276,308]	0	hSpCas9	negative selection	6864675
140834669	140834692	7	+	27260156	G402	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.577393860773726	[554]	[1335,1274,659,837]	7	hSpCas9	negative selection	6864676
140808947	140808970	7	+	27260156	G402	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.48238168315986335	[571]	[945,1464,962,566]	6	hSpCas9	negative selection	6928958
140808984	140809007	7	-	27260156	G402	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.5686895803172484	[1036]	[997,982,482,967]	-6	hSpCas9	negative selection	6928959
140834720	140834743	7	+	27260156	G402	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.5358577030443181	[525]	[619,379,495,301]	-6	hSpCas9	negative selection	6928960
140850140	140850163	7	+	27260156	L33	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.7716882862965271	[607]	[1096,422,546,1148]	9	hSpCas9	negative selection	6985925
140850145	140850168	7	-	27260156	L33	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	-0.06687361525926239	[232]	[185,112,136,210]	-1	hSpCas9	negative selection	6985926
140834669	140834692	7	+	27260156	L33	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.1813384901615906	[554]	[752,225,374,612]	4	hSpCas9	negative selection	6985927
140808947	140808970	7	+	27260156	L33	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.27944981571901956	[571]	[662,241,539,665]	6	hSpCas9	negative selection	7050209
140808984	140809007	7	-	27260156	L33	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.5618726045362802	[1036]	[732,249,429,780]	-8	hSpCas9	negative selection	7050210
140834720	140834743	7	+	27260156	L33	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.020490927580684992	[525]	[614,217,272,549]	0	hSpCas9	negative selection	7050211
140850140	140850163	7	+	27260156	K562	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.6931396436166162	[607]	[822,802,1073,787]	8	hSpCas9	negative selection	7107176
140850145	140850168	7	-	27260156	K562	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.18399141851146983	[232]	[388,217,246,110]	2	hSpCas9	negative selection	7107177
140834669	140834692	7	+	27260156	K562	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.12641668139474832	[554]	[511,392,591,322]	-2	hSpCas9	negative selection	7107178
140808947	140808970	7	+	27260156	K562	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.37531118566831184	[571]	[747,677,608,609]	5	hSpCas9	negative selection	7171460
140808984	140809007	7	-	27260156	K562	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-1.2396461300768575	[1036]	[367,689,319,213]	-8	hSpCas9	negative selection	7171461
140834720	140834743	7	+	27260156	K562	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-1.6822496878872608	[525]	[61,152,112,235]	-9	hSpCas9	negative selection	7171462
140850140	140850163	7	+	27260156	HT29	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.738052803839272	[607]	[1485,1157,1362,961]	9	hSpCas9	negative selection	7228427
140850145	140850168	7	-	27260156	HT29	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.049196719599494676	[232]	[241,348,304,276]	0	hSpCas9	negative selection	7228428
140834669	140834692	7	+	27260156	HT29	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.29724759791086797	[554]	[819,622,349,439]	-5	hSpCas9	negative selection	7228429
140808947	140808970	7	+	27260156	HT29	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	-0.3483481025774512	[571]	[625,510,618,440]	-6	hSpCas9	negative selection	7292711
140808984	140809007	7	-	27260156	HT29	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-1.6207028920435642	[1036]	[473,440,343,387]	-9	hSpCas9	negative selection	7292712
140834720	140834743	7	+	27260156	HT29	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-1.2633976914128864	[525]	[248,295,309,215]	-9	hSpCas9	negative selection	7292713
140850140	140850163	7	+	27260156	MHHES1	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.780825491281411	[607]	[1040,1274,1269,1103]	9	hSpCas9	negative selection	7349678
140850145	140850168	7	-	27260156	MHHES1	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.06648005695275028	[232]	[359,190,341,215]	1	hSpCas9	negative selection	7349679
140834669	140834692	7	+	27260156	MHHES1	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.32936732905979804	[554]	[870,839,883,590]	6	hSpCas9	negative selection	7349680
140808947	140808970	7	+	27260156	MHHES1	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.37209185101485603	[571]	[1102,817,797,666]	6	hSpCas9	negative selection	7413962
140808984	140809007	7	-	27260156	MHHES1	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.6456847103079131	[1036]	[915,853,626,629]	-8	hSpCas9	negative selection	7413963
140834720	140834743	7	+	27260156	MHHES1	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.2846916731087422	[525]	[439,425,687,391]	-5	hSpCas9	negative selection	7413964
140850140	140850163	7	+	27260156	MEWO	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.4073517799283741	[607]	[896,683,709]	8	hSpCas9	negative selection	7470929
140850145	140850168	7	-	27260156	MEWO	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.48274870026913375	[232]	[328,201,387]	8	hSpCas9	negative selection	7470930
140834669	140834692	7	+	27260156	MEWO	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.2283953916830211	[554]	[647,702,480]	5	hSpCas9	negative selection	7470931
140808947	140808970	7	+	27260156	MEWO	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.6668357707448109	[571]	[1026,835,719]	9	hSpCas9	negative selection	7535213
140808984	140809007	7	-	27260156	MEWO	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.5435939693192577	[1036]	[753,619,639]	-8	hSpCas9	negative selection	7535214
140834720	140834743	7	+	27260156	MEWO	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.2922341064136412	[525]	[512,412,300]	-6	hSpCas9	negative selection	7535215
140850140	140850163	7	+	27260156	LNCAPCLONEFGC	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.7432681352310839	[607]	[800,624,1250,1080]	9	hSpCas9	negative selection	7592180
140850145	140850168	7	-	27260156	LNCAPCLONEFGC	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.33494630009345994	[232]	[271,206,282,308]	5	hSpCas9	negative selection	7592181
140834669	140834692	7	+	27260156	LNCAPCLONEFGC	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.12611339007262679	[554]	[488,460,694,577]	2	hSpCas9	negative selection	7592182
140808947	140808970	7	+	27260156	LNCAPCLONEFGC	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.23235842684518054	[571]	[671,583,744,453]	3	hSpCas9	negative selection	7656464
140808984	140809007	7	-	27260156	LNCAPCLONEFGC	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.3348018053344455	[1036]	[663,706,792,825]	-5	hSpCas9	negative selection	7656465
140834720	140834743	7	+	27260156	LNCAPCLONEFGC	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.2806022113450859	[525]	[371,343,436,425]	-4	hSpCas9	negative selection	7656466
140850140	140850163	7	+	27260156	PANC0327	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.9719975454686709	[607]	[1385,629,1293,1009]	9	hSpCas9	negative selection	7713431
140850145	140850168	7	-	27260156	PANC0327	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.43737578947232625	[232]	[509,247,224,160]	6	hSpCas9	negative selection	7713432
140834669	140834692	7	+	27260156	PANC0327	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.0740309653551228	[554]	[464,529,437,431]	-1	hSpCas9	negative selection	7713433
140808947	140808970	7	+	27260156	PANC0327	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.4009882423100631	[571]	[818,652,670,554]	6	hSpCas9	negative selection	7777715
140808984	140809007	7	-	27260156	PANC0327	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.23322736027671798	[1036]	[573,712,1122,716]	-3	hSpCas9	negative selection	7777716
140834720	140834743	7	+	27260156	PANC0327	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.041761944329542375	[525]	[406,460,558,383]	0	hSpCas9	negative selection	7777717
140850140	140850163	7	+	27260156	NCIH2009	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	1.3065063660601413	[607]	[2341,2119,1884]	9	hSpCas9	negative selection	7834682
140850145	140850168	7	-	27260156	NCIH2009	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.2856720977463635	[232]	[347,514,314]	4	hSpCas9	negative selection	7834683
140834669	140834692	7	+	27260156	NCIH2009	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.41344502116480886	[554]	[1143,839,1137]	6	hSpCas9	negative selection	7834684
140808947	140808970	7	+	27260156	NCIH2009	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.011678333753321113	[571]	[1031,605,825]	0	hSpCas9	negative selection	7898966
140808984	140809007	7	-	27260156	NCIH2009	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.5686224910095318	[1036]	[1068,1045,830]	-6	hSpCas9	negative selection	7898967
140834720	140834743	7	+	27260156	NCIH2009	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.5379108184555601	[525]	[670,409,470]	-6	hSpCas9	negative selection	7898968
140850140	140850163	7	+	27260156	NCIH1373	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	1.5416445433345094	[607]	[2406,2019,1228,622]	9	hSpCas9	negative selection	7955933
140850145	140850168	7	-	27260156	NCIH1373	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.23564159535362517	[232]	[451,246,289,69]	2	hSpCas9	negative selection	7955934
140834669	140834692	7	+	27260156	NCIH1373	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.5487285691132914	[554]	[839,826,930,273]	5	hSpCas9	negative selection	7955935
140808947	140808970	7	+	27260156	NCIH1373	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.6523379068538537	[571]	[1348,743,1033,256]	6	hSpCas9	negative selection	8020217
140808984	140809007	7	-	27260156	NCIH1373	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.3290166610455545	[1036]	[917,562,1498,191]	-3	hSpCas9	negative selection	8020218
140834720	140834743	7	+	27260156	NCIH1373	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.1322309409129375	[525]	[659,536,530,113]	-1	hSpCas9	negative selection	8020219
140850140	140850163	7	+	27260156	PATU8902	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	1.0056838290109296	[607]	[2146,1537,1403,1777]	9	hSpCas9	negative selection	8077184
140850145	140850168	7	-	27260156	PATU8902	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	-0.1920128232657472	[232]	[265,237,145,551]	-2	hSpCas9	negative selection	8077185
140834669	140834692	7	+	27260156	PATU8902	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.1420859637797049	[554]	[806,1150,642,860]	1	hSpCas9	negative selection	8077186
140808947	140808970	7	+	27260156	PATU8902	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	-0.14362496096500704	[571]	[691,802,610,812]	-1	hSpCas9	negative selection	8141468
140808984	140809007	7	-	27260156	PATU8902	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-1.204778819958681	[1036]	[607,575,280,1193]	-8	hSpCas9	negative selection	8141469
140834720	140834743	7	+	27260156	PATU8902	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.8793263665361672	[525]	[515,401,279,423]	-7	hSpCas9	negative selection	8141470
140850140	140850163	7	+	27260156	PANC1	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.6030538357666947	[607]	[620,1194,902,565]	8	hSpCas9	negative selection	8198435
140850145	140850168	7	-	27260156	PANC1	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.23745131736806646	[232]	[215,317,208,216]	4	hSpCas9	negative selection	8198436
140834669	140834692	7	+	27260156	PANC1	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	-0.05990796260831599	[554]	[491,535,462,361]	-1	hSpCas9	negative selection	8198437
140808947	140808970	7	+	27260156	PANC1	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.06473364510958957	[571]	[528,664,485,413]	1	hSpCas9	negative selection	8262719
140808984	140809007	7	-	27260156	PANC1	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.7614460363335741	[1036]	[399,561,775,389]	-8	hSpCas9	negative selection	8262720
140834720	140834743	7	+	27260156	PANC1	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.06654615929628284	[525]	[268,589,557,351]	-1	hSpCas9	negative selection	8262721
140850140	140850163	7	+	27260156	PANC0813	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.920253683340948	[607]	[1847,1208,1203,1196]	9	hSpCas9	negative selection	8319686
140850145	140850168	7	-	27260156	PANC0813	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.4385196838187334	[232]	[381,329,448,325]	7	hSpCas9	negative selection	8319687
140834669	140834692	7	+	27260156	PANC0813	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.6257675466525947	[554]	[900,1028,1012,1065]	8	hSpCas9	negative selection	8319688
140808947	140808970	7	+	27260156	PANC0813	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.3196245692090252	[571]	[811,928,720,884]	5	hSpCas9	negative selection	8383970
140808984	140809007	7	-	27260156	PANC0813	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.11321492369186847	[1036]	[1137,1359,1074,940]	-2	hSpCas9	negative selection	8383971
140834720	140834743	7	+	27260156	PANC0813	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.0835261630223421	[525]	[701,549,573,519]	-1	hSpCas9	negative selection	8383972
140850140	140850163	7	+	27260156	RDES	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.7192160950671176	[607]	[996,917,1420,1325]	9	hSpCas9	negative selection	8440937
140850145	140850168	7	-	27260156	RDES	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.11810491262565603	[232]	[226,338,225,382]	2	hSpCas9	negative selection	8440938
140834669	140834692	7	+	27260156	RDES	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.286202821210898	[554]	[551,709,906,1019]	4	hSpCas9	negative selection	8440939
140808947	140808970	7	+	27260156	RDES	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.521798894789814	[571]	[881,793,865,1281]	8	hSpCas9	negative selection	8505221
140808984	140809007	7	-	27260156	RDES	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.433165266328142	[1036]	[792,774,832,1176]	-6	hSpCas9	negative selection	8505222
140834720	140834743	7	+	27260156	RDES	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.45755052903422755	[525]	[416,539,443,322]	-7	hSpCas9	negative selection	8505223
140850140	140850163	7	+	27260156	PC3	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.4059375703916883	[607]	[506,824,1267,843]	8	hSpCas9	negative selection	8562188
140850145	140850168	7	-	27260156	PC3	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.03305288826202202	[232]	[164,295,205,274]	0	hSpCas9	negative selection	8562189
140834669	140834692	7	+	27260156	PC3	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.26232320331550574	[554]	[506,587,1244,530]	6	hSpCas9	negative selection	8562190
140808947	140808970	7	+	27260156	PC3	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.47228481478387635	[571]	[522,648,1548,783]	8	hSpCas9	negative selection	8626472
140808984	140809007	7	-	27260156	PC3	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.4768650504311873	[1036]	[587,651,1145,724]	-8	hSpCas9	negative selection	8626473
140834720	140834743	7	+	27260156	PC3	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.18360837854731682	[525]	[254,687,639,363]	-4	hSpCas9	negative selection	8626474
140850140	140850163	7	+	27260156	PATU8988T	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.5885890959104336	[607]	[966,761,909,882]	8	hSpCas9	negative selection	8683439
140850145	140850168	7	-	27260156	PATU8988T	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.6262220574036237	[232]	[547,320,133,390]	8	hSpCas9	negative selection	8683440
140834669	140834692	7	+	27260156	PATU8988T	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.38432776477880504	[554]	[617,556,542,1102]	6	hSpCas9	negative selection	8683441
140808947	140808970	7	+	27260156	PATU8988T	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.08030324609004941	[571]	[546,458,454,890]	1	hSpCas9	negative selection	8747723
140808984	140809007	7	-	27260156	PATU8988T	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.3988262320761129	[1036]	[741,650,788,854]	-6	hSpCas9	negative selection	8747724
140834720	140834743	7	+	27260156	PATU8988T	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.0028873819217924424	[525]	[483,477,614,450]	0	hSpCas9	negative selection	8747725
140850140	140850163	7	+	27260156	T47D	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.6492986222533799	[607]	[981,895,1301,1283]	9	hSpCas9	negative selection	8804690
140850145	140850168	7	-	27260156	T47D	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.2761656785863814	[232]	[368,285,324,338]	6	hSpCas9	negative selection	8804691
140834669	140834692	7	+	27260156	T47D	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.3354606102851895	[554]	[859,801,763,839]	7	hSpCas9	negative selection	8804692
140808947	140808970	7	+	27260156	T47D	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.5734776621162101	[571]	[1100,809,958,1116]	9	hSpCas9	negative selection	8868974
140808984	140809007	7	-	27260156	T47D	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.3347626005941534	[1036]	[911,1005,890,1020]	-6	hSpCas9	negative selection	8868975
140834720	140834743	7	+	27260156	T47D	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.12114608582098232	[525]	[572,601,552,520]	-3	hSpCas9	negative selection	8868976
140850140	140850163	7	+	27260156	SU8686	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.9259878820182179	[607]	[862,958,1421,1440]	9	hSpCas9	negative selection	8925941
140850145	140850168	7	-	27260156	SU8686	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.33598558948268153	[232]	[412,196,195,365]	5	hSpCas9	negative selection	8925942
140834669	140834692	7	+	27260156	SU8686	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.6077025295319243	[554]	[700,616,840,1309]	8	hSpCas9	negative selection	8925943
140808947	140808970	7	+	27260156	SU8686	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.6432900631588092	[571]	[703,698,1087,1136]	9	hSpCas9	negative selection	8990225
140808984	140809007	7	-	27260156	SU8686	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.3131101296570099	[1036]	[705,797,884,954]	-5	hSpCas9	negative selection	8990226
140834720	140834743	7	+	27260156	SU8686	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.16753946850924473	[525]	[632,498,661,545]	3	hSpCas9	negative selection	8990227
140850140	140850163	7	+	27260156	SKES1	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.6091919971370013	[607]	[889,1102,997,737]	9	hSpCas9	negative selection	9047192
140850145	140850168	7	-	27260156	SKES1	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	-0.5441205343877464	[232]	[164,210,174,98]	-8	hSpCas9	negative selection	9047193
140834669	140834692	7	+	27260156	SKES1	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.1041795884082184	[554]	[541,734,651,468]	2	hSpCas9	negative selection	9047194
140808947	140808970	7	+	27260156	SKES1	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.5447045127742791	[571]	[757,930,827,807]	9	hSpCas9	negative selection	9111476
140808984	140809007	7	-	27260156	SKES1	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.5033052002910887	[1036]	[735,789,764,638]	-8	hSpCas9	negative selection	9111477
140834720	140834743	7	+	27260156	SKES1	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.3082895000262005	[525]	[340,452,474,413]	-6	hSpCas9	negative selection	9111478
140850140	140850163	7	+	27260156	TOV112D	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.5465851011551148	[607]	[563,1476,689,940]	8	hSpCas9	negative selection	9168443
140850145	140850168	7	-	27260156	TOV112D	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.42050648144853653	[232]	[286,218,524,195]	7	hSpCas9	negative selection	9168444
140834669	140834692	7	+	27260156	TOV112D	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.17616893111491244	[554]	[530,1044,487,543]	3	hSpCas9	negative selection	9168445
140808947	140808970	7	+	27260156	TOV112D	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.3990995565635141	[571]	[910,853,503,787]	7	hSpCas9	negative selection	9232727
140808984	140809007	7	-	27260156	TOV112D	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.5942686257923175	[1036]	[824,891,536,561]	-8	hSpCas9	negative selection	9232728
140834720	140834743	7	+	27260156	TOV112D	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.26708172379099815	[525]	[367,491,355,538]	-5	hSpCas9	negative selection	9232729
140850140	140850163	7	+	27260156	TC71	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.46753445614670985	[607]	[939,853,923,883]	9	hSpCas9	negative selection	9289694
140850145	140850168	7	-	27260156	TC71	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.24808709328363843	[232]	[359,305,218,302]	6	hSpCas9	negative selection	9289695
140834669	140834692	7	+	27260156	TC71	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.2652039942003661	[554]	[675,692,722,771]	6	hSpCas9	negative selection	9289696
140808947	140808970	7	+	27260156	TC71	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.39606350207878244	[571]	[772,828,785,842]	8	hSpCas9	negative selection	9353978
140808984	140809007	7	-	27260156	TC71	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.5787859876370176	[1036]	[691,691,813,779]	-9	hSpCas9	negative selection	9353979
140834720	140834743	7	+	27260156	TC71	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.10396746302846588	[525]	[553,482,470,595]	-3	hSpCas9	negative selection	9353980
140850140	140850163	7	+	27260156	TC32	viability	CCCCACCAAATTTGTCCAATAGG	BRAF	ENSG00000157764	0.7319023171824799	[607]	[791,849,1330,883]	9	hSpCas9	negative selection	9410945
140850145	140850168	7	-	27260156	TC32	viability	GAGGCCCTATTGGACAAATTTGG	BRAF	ENSG00000157764	0.4452025748220756	[232]	[152,245,489,361]	7	hSpCas9	negative selection	9410946
140834669	140834692	7	+	27260156	TC32	viability	GTTGCTCCGTGCCACATCTGTGG	BRAF	ENSG00000157764	0.06465183542510866	[554]	[492,461,827,446]	1	hSpCas9	negative selection	9410947
140808947	140808970	7	+	27260156	TC32	viability	GTGCTTTCTTTAGACTGTCTCGG	BRAF	ENSG00000157764	0.32152420263656106	[571]	[696,585,850,563]	5	hSpCas9	negative selection	9475229
140808984	140809007	7	-	27260156	TC32	viability	TGATACCATAGGTACCTGCAAGG	BRAF	ENSG00000157764	-0.5311548977996122	[1036]	[695,485,835,738]	-7	hSpCas9	negative selection	9475230
140834720	140834743	7	+	27260156	TC32	viability	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.3595847362537965	[525]	[191,428,507,418]	-6	hSpCas9	negative selection	9475231
140800358	140800381	7	+	27869803	HPAFII	viability after 27 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.8459597546896571	[160]	[27,62,NaN]	-5	hSpCas9	negative selection	9598327
140800435	140800458	7	-	27869803	HPAFII	viability after 27 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.5540559005022634	[310]	[172,59,NaN]	-4	hSpCas9	negative selection	9598328
140801443	140801466	7	+	27869803	HPAFII	viability after 27 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	0.20333222456260283	[242]	[103,182,NaN]	1	hSpCas9	negative selection	9598329
140834720	140834743	7	+	27869803	HPAFII	viability after 27 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.26999728148946667	[224]	[110,168,NaN]	2	hSpCas9	negative selection	9598330
140924557	140924580	7	+	27869803	HPAFII	viability after 27 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.17725688045390936	[261]	[219,39,NaN]	-1	hSpCas9	negative selection	9598331
140924562	140924585	7	+	27869803	HPAFII	viability after 27 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.6040732021792514	[255]	[75,98,NaN]	-4	hSpCas9	negative selection	9598332
140800358	140800381	7	+	27869803	HPAFII	viability after 15 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.1009474804028897	[160]	[245,147,NaN]	1	hSpCas9	negative selection	9680776
140800435	140800458	7	-	27869803	HPAFII	viability after 15 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	0.25569790600527303	[310]	[448,367,NaN]	3	hSpCas9	negative selection	9680777
140801443	140801466	7	+	27869803	HPAFII	viability after 15 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	0.39111385218105066	[242]	[368,325,NaN]	4	hSpCas9	negative selection	9680778
140834720	140834743	7	+	27869803	HPAFII	viability after 15 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.17003692308993376	[224]	[172,240,NaN]	-2	hSpCas9	negative selection	9680779
140924557	140924580	7	+	27869803	HPAFII	viability after 15 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	0.47502841782393257	[261]	[703,196,NaN]	5	hSpCas9	negative selection	9680780
140924562	140924585	7	+	27869803	HPAFII	viability after 15 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	0.1368760307332245	[255]	[431,221,NaN]	1	hSpCas9	negative selection	9680781
140800358	140800381	7	+	27869803	ASPC1	viability after 36 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	1.2465733538503392	[329]	[326,359,163]	9	hSpCas9	negative selection	9763225
140800435	140800458	7	-	27869803	ASPC1	viability after 36 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.6793012130454917	[757]	[177,209,118]	-6	hSpCas9	negative selection	9763226
140801443	140801466	7	+	27869803	ASPC1	viability after 36 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.6157610983292725	[710]	[172,178,138]	-6	hSpCas9	negative selection	9763227
140834720	140834743	7	+	27869803	ASPC1	viability after 36 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.6186547913567543	[626]	[179,325,449]	6	hSpCas9	negative selection	9763228
140924557	140924580	7	+	27869803	ASPC1	viability after 36 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.0250581669117928	[842]	[508,268,147]	0	hSpCas9	negative selection	9763229
140924562	140924585	7	+	27869803	ASPC1	viability after 36 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.576751115661681	[551]	[176,218,22]	-5	hSpCas9	negative selection	9763230
140800358	140800381	7	+	27869803	PATU8988S	viability after 35 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.874789068617832	[431]	[42,146,NaN]	-7	hSpCas9	negative selection	9845674
140800435	140800458	7	-	27869803	PATU8988S	viability after 35 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	0.14816549804599444	[894]	[376,421,NaN]	1	hSpCas9	negative selection	9845675
140801443	140801466	7	+	27869803	PATU8988S	viability after 35 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.4623969937583876	[652]	[136,244,NaN]	-5	hSpCas9	negative selection	9845676
140834720	140834743	7	+	27869803	PATU8988S	viability after 35 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.37911394810823124	[488]	[121,180,NaN]	-4	hSpCas9	negative selection	9845677
140924557	140924580	7	+	27869803	PATU8988S	viability after 35 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.05363899033622099	[727]	[282,281,NaN]	0	hSpCas9	negative selection	9845678
140924562	140924585	7	+	27869803	PATU8988S	viability after 35 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	0.1093197663304005	[571]	[251,244,NaN]	1	hSpCas9	negative selection	9845679
140800358	140800381	7	+	27869803	PATU8988S	viability after 31 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.5458327101684678	[431]	[95,145,NaN]	-5	hSpCas9	negative selection	9928123
140800435	140800458	7	-	27869803	PATU8988S	viability after 31 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	0.1324089421395125	[894]	[289,519,NaN]	1	hSpCas9	negative selection	9928124
140801443	140801466	7	+	27869803	PATU8988S	viability after 31 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.5256566963750996	[652]	[135,237,NaN]	-5	hSpCas9	negative selection	9928125
140834720	140834743	7	+	27869803	PATU8988S	viability after 31 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	-0.18309050828796847	[488]	[103,257,NaN]	-2	hSpCas9	negative selection	9928126
140924557	140924580	7	+	27869803	PATU8988S	viability after 31 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.07981324348324081	[727]	[187,384,NaN]	-1	hSpCas9	negative selection	9928127
140924562	140924585	7	+	27869803	PATU8988S	viability after 31 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-0.08071440665737167	[571]	[172,269,NaN]	-1	hSpCas9	negative selection	9928128
140800358	140800381	7	+	27869803	HPAFII	viability after 35 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.6903345753305792	[160]	[10,94,NaN]	-4	hSpCas9	negative selection	10010572
140800435	140800458	7	-	27869803	HPAFII	viability after 35 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.5570020744451858	[310]	[138,70,NaN]	-3	hSpCas9	negative selection	10010573
140801443	140801466	7	+	27869803	HPAFII	viability after 35 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	0.7772126791348725	[242]	[223,195,NaN]	5	hSpCas9	negative selection	10010574
140834720	140834743	7	+	27869803	HPAFII	viability after 35 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.42132797898541263	[224]	[49,267,NaN]	2	hSpCas9	negative selection	10010575
140924557	140924580	7	+	27869803	HPAFII	viability after 35 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	0.2885859520329303	[261]	[296,9,NaN]	1	hSpCas9	negative selection	10010576
140924562	140924585	7	+	27869803	HPAFII	viability after 35 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-1.1040050372777603	[255]	[56,63,NaN]	-6	hSpCas9	negative selection	10010577
140800358	140800381	7	+	27869803	HPAFII	viability after 31 days	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.4302265688611555	[160]	[45,89,NaN]	-3	hSpCas9	negative selection	10093021
140800435	140800458	7	-	27869803	HPAFII	viability after 31 days	TGAACACCACCCAATACCACAGG	BRAF	ENSG00000157764	-0.7424090721656125	[310]	[133,71,NaN]	-5	hSpCas9	negative selection	10093022
140801443	140801466	7	+	27869803	HPAFII	viability after 31 days	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	0.20219455810463427	[242]	[120,195,NaN]	1	hSpCas9	negative selection	10093023
140834720	140834743	7	+	27869803	HPAFII	viability after 31 days	TAGCACTGAAAGGCTAGAAGAGG	BRAF	ENSG00000157764	0.22674381379885988	[224]	[108,189,NaN]	1	hSpCas9	negative selection	10093024
140924557	140924580	7	+	27869803	HPAFII	viability after 31 days	AGCACTCACCTCCTCCGGAATGG	BRAF	ENSG00000157764	-0.11054457125439578	[261]	[240,21,NaN]	0	hSpCas9	negative selection	10093025
140924562	140924585	7	+	27869803	HPAFII	viability after 31 days	TCACCTCCTCCGGAATGGCAGGG	BRAF	ENSG00000157764	-1.0035901844676696	[255]	[63,79,NaN]	-6	hSpCas9	negative selection	10093026
140924684	140924707	7	-	28162770	P31FUJ	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-2.7275668961639563	[61]	[10]	-9	hSpCas9	negative selection	10118970
140924584	140924607	7	+	28162770	P31FUJ	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.3413266611925476	[620]	[575]	-3	hSpCas9	negative selection	10118971
140800358	140800381	7	+	28162770	P31FUJ	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.0638730985410722	[218]	[268]	0	hSpCas9	negative selection	10118972
140783108	140783131	7	+	28162770	P31FUJ	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	0.667662122034707	[194]	[363]	7	hSpCas9	negative selection	10118973
140924640	140924663	7	-	28162770	P31FUJ	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-1.4216215176091616	[268]	[117]	-7	hSpCas9	negative selection	10118974
140924625	140924648	7	-	28162770	P31FUJ	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	-1.2807366814780805	[152]	[73]	-7	hSpCas9	negative selection	10118975
140834615	140834638	7	-	28162770	P31FUJ	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-0.14433341655206466	[505]	[537]	-1	hSpCas9	negative selection	10118976
140801443	140801466	7	+	28162770	P31FUJ	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-1.2671537092051555	[169]	[82]	-7	hSpCas9	negative selection	10118977
140800429	140800452	7	-	28162770	P31FUJ	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	0.6199326211472345	[303]	[548]	7	hSpCas9	negative selection	10118978
140794410	140794433	7	+	28162770	P31FUJ	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	-0.808886553789082	[242]	[162]	-6	hSpCas9	negative selection	10118979
140924684	140924707	7	-	28162770	TF1	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10288336
140924584	140924607	7	+	28162770	TF1	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	NaN	[NaN]	[288]	1	hSpCas9	negative selection	10288337
140800358	140800381	7	+	28162770	TF1	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10288338
140783108	140783131	7	+	28162770	TF1	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10288339
140924640	140924663	7	-	28162770	TF1	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10288340
140924625	140924648	7	-	28162770	TF1	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10288341
140834615	140834638	7	-	28162770	TF1	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	NaN	[NaN]	[260]	1	hSpCas9	negative selection	10288342
140801443	140801466	7	+	28162770	TF1	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10288343
140800429	140800452	7	-	28162770	TF1	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	NaN	[NaN]	[146]	1	hSpCas9	negative selection	10288344
140794410	140794433	7	+	28162770	TF1	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10288345
140924684	140924707	7	-	28162770	SKM1	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-1.2370391973008492	[7]	[5]	-7	hSpCas9	negative selection	10457702
140924584	140924607	7	+	28162770	SKM1	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-1.7080455087249198	[145]	[78]	-8	hSpCas9	negative selection	10457703
140800358	140800381	7	+	28162770	SKM1	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-1.019038545081559	[46]	[40]	-6	hSpCas9	negative selection	10457704
140783108	140783131	7	+	28162770	SKM1	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	-1.0797994554896522	[54]	[45]	-7	hSpCas9	negative selection	10457705
140924640	140924663	7	-	28162770	SKM1	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-1.5444677224930967	[65]	[39]	-8	hSpCas9	negative selection	10457706
140924625	140924648	7	-	28162770	SKM1	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	-2.547826734583011	[42]	[12]	-9	hSpCas9	negative selection	10457707
140834615	140834638	7	-	28162770	SKM1	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-1.7805817706420246	[102]	[52]	-8	hSpCas9	negative selection	10457708
140801443	140801466	7	+	28162770	SKM1	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-1.5100576917072654	[28]	[17]	-7	hSpCas9	negative selection	10457709
140800429	140800452	7	-	28162770	SKM1	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	-0.8220016980220055	[61]	[61]	-6	hSpCas9	negative selection	10457710
140794410	140794433	7	+	28162770	SKM1	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	-0.576889200185474	[53]	[63]	-4	hSpCas9	negative selection	10457711
140924684	140924707	7	-	28162770	SKM1	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-1.2370391973008492	[7]	[5]	-7	hSpCas9	negative selection	10627068
140924584	140924607	7	+	28162770	SKM1	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-1.7080455087249198	[145]	[78]	-8	hSpCas9	negative selection	10627069
140800358	140800381	7	+	28162770	SKM1	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-1.019038545081559	[46]	[40]	-6	hSpCas9	negative selection	10627070
140783108	140783131	7	+	28162770	SKM1	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	-1.0797994554896522	[54]	[45]	-7	hSpCas9	negative selection	10627071
140924640	140924663	7	-	28162770	SKM1	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-1.5444677224930967	[65]	[39]	-8	hSpCas9	negative selection	10627072
140924625	140924648	7	-	28162770	SKM1	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	-2.547826734583011	[42]	[12]	-9	hSpCas9	negative selection	10627073
140834615	140834638	7	-	28162770	SKM1	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-1.7805817706420246	[102]	[52]	-8	hSpCas9	negative selection	10627074
140801443	140801466	7	+	28162770	SKM1	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-1.5100576917072654	[28]	[17]	-7	hSpCas9	negative selection	10627075
140800429	140800452	7	-	28162770	SKM1	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	-0.8220016980220055	[61]	[61]	-6	hSpCas9	negative selection	10627076
140794410	140794433	7	+	28162770	SKM1	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	-0.576889200185474	[53]	[63]	-4	hSpCas9	negative selection	10627077
140924684	140924707	7	-	28162770	PL21	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-0.684383168090744	[47]	[12]	-5	hSpCas9	negative selection	10796434
140924584	140924607	7	+	28162770	PL21	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.4653128040922039	[386]	[121]	-3	hSpCas9	negative selection	10796435
140800358	140800381	7	+	28162770	PL21	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.18068216945161075	[249]	[95]	-1	hSpCas9	negative selection	10796436
140783108	140783131	7	+	28162770	PL21	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	-0.7384598408465366	[252]	[65]	-5	hSpCas9	negative selection	10796437
140924640	140924663	7	-	28162770	PL21	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	0.3044762743040559	[239]	[128]	2	hSpCas9	negative selection	10796438
140924625	140924648	7	-	28162770	PL21	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	-0.3730457184554826	[121]	[40]	-3	hSpCas9	negative selection	10796439
140834615	140834638	7	-	28162770	PL21	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-0.051399152506644286	[299]	[125]	0	hSpCas9	negative selection	10796440
140801443	140801466	7	+	28162770	PL21	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.819225710377611	[149]	[36]	-5	hSpCas9	negative selection	10796441
140800429	140800452	7	-	28162770	PL21	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	0.8281708371023625	[153]	[118]	7	hSpCas9	negative selection	10796442
140794410	140794433	7	+	28162770	PL21	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	0.22762035091142702	[207]	[105]	2	hSpCas9	negative selection	10796443
140924684	140924707	7	-	28162770	P31FUJ	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-2.7275668961639563	[61]	[10]	-9	hSpCas9	negative selection	10965800
140924584	140924607	7	+	28162770	P31FUJ	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.3413266611925476	[620]	[575]	-3	hSpCas9	negative selection	10965801
140800358	140800381	7	+	28162770	P31FUJ	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.0638730985410722	[218]	[268]	0	hSpCas9	negative selection	10965802
140783108	140783131	7	+	28162770	P31FUJ	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	0.667662122034707	[194]	[363]	7	hSpCas9	negative selection	10965803
140924640	140924663	7	-	28162770	P31FUJ	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-1.4216215176091616	[268]	[117]	-7	hSpCas9	negative selection	10965804
140924625	140924648	7	-	28162770	P31FUJ	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	-1.2807366814780805	[152]	[73]	-7	hSpCas9	negative selection	10965805
140834615	140834638	7	-	28162770	P31FUJ	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-0.14433341655206466	[505]	[537]	-1	hSpCas9	negative selection	10965806
140801443	140801466	7	+	28162770	P31FUJ	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-1.2671537092051555	[169]	[82]	-7	hSpCas9	negative selection	10965807
140800429	140800452	7	-	28162770	P31FUJ	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	0.6199326211472345	[303]	[548]	7	hSpCas9	negative selection	10965808
140794410	140794433	7	+	28162770	P31FUJ	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	-0.808886553789082	[242]	[162]	-6	hSpCas9	negative selection	10965809
140924684	140924707	7	-	28162770	OCIAML5	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-3.8520665708639967	[31]	[3]	-9	hSpCas9	negative selection	11135166
140924584	140924607	7	+	28162770	OCIAML5	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.46409731478332394	[268]	[351]	-3	hSpCas9	negative selection	11135167
140800358	140800381	7	+	28162770	OCIAML5	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.6069540730274655	[107]	[127]	-4	hSpCas9	negative selection	11135168
140783108	140783131	7	+	28162770	OCIAML5	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	0.5941896590255669	[79]	[217]	5	hSpCas9	negative selection	11135169
140924640	140924663	7	-	28162770	OCIAML5	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-0.7288348048697261	[156]	[170]	-5	hSpCas9	negative selection	11135170
140924625	140924648	7	-	28162770	OCIAML5	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	0.4949525049861959	[56]	[144]	4	hSpCas9	negative selection	11135171
140834615	140834638	7	-	28162770	OCIAML5	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-0.6421847879962971	[363]	[420]	-4	hSpCas9	negative selection	11135172
140801443	140801466	7	+	28162770	OCIAML5	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.5704962135927757	[115]	[140]	-4	hSpCas9	negative selection	11135173
140800429	140800452	7	-	28162770	OCIAML5	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	0.4340514480828381	[154]	[377]	4	hSpCas9	negative selection	11135174
140794410	140794433	7	+	28162770	OCIAML5	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	-1.0009299567784797	[152]	[137]	-6	hSpCas9	negative selection	11135175
140924684	140924707	7	-	28162770	EOL1	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	0.37200674854175597	[87]	[59]	3	hSpCas9	negative selection	11304532
140924584	140924607	7	+	28162770	EOL1	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.4647796086024143	[481]	[183]	-3	hSpCas9	negative selection	11304533
140800358	140800381	7	+	28162770	EOL1	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.1271269391238296	[397]	[228]	1	hSpCas9	negative selection	11304534
140783108	140783131	7	+	28162770	EOL1	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	0.08056392752220787	[358]	[199]	0	hSpCas9	negative selection	11304535
140924640	140924663	7	-	28162770	EOL1	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-0.25117951593831156	[435]	[192]	-2	hSpCas9	negative selection	11304536
140924625	140924648	7	-	28162770	EOL1	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	0.4651161529332373	[274]	[199]	4	hSpCas9	negative selection	11304537
140834615	140834638	7	-	28162770	EOL1	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	0.30684848443737867	[467]	[304]	3	hSpCas9	negative selection	11304538
140801443	140801466	7	+	28162770	EOL1	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	1.4407975222076765	[171]	[245]	9	hSpCas9	negative selection	11304539
140800429	140800452	7	-	28162770	EOL1	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	0.6737396680700003	[281]	[236]	6	hSpCas9	negative selection	11304540
140794410	140794433	7	+	28162770	EOL1	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	1.2283285197476375	[255]	[315]	8	hSpCas9	negative selection	11304541
140924684	140924707	7	-	28162770	MOLM13	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-0.3599296430727412	[70]	[39]	-2	hSpCas9	negative selection	11473898
140924584	140924607	7	+	28162770	MOLM13	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	0.23188031284221888	[549]	[466]	1	hSpCas9	negative selection	11473899
140800358	140800381	7	+	28162770	MOLM13	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	1.6297770639214728	[239]	[536]	9	hSpCas9	negative selection	11473900
140783108	140783131	7	+	28162770	MOLM13	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	1.6951230659505259	[339]	[795]	9	hSpCas9	negative selection	11473901
140924640	140924663	7	-	28162770	MOLM13	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	0.647560927896405	[376]	[426]	5	hSpCas9	negative selection	11473902
140924625	140924648	7	-	28162770	MOLM13	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	1.0589263966754192	[157]	[237]	7	hSpCas9	negative selection	11473903
140834615	140834638	7	-	28162770	MOLM13	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	0.2508902189783493	[622]	[535]	1	hSpCas9	negative selection	11473904
140801443	140801466	7	+	28162770	MOLM13	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.5927734003620454	[339]	[162]	-3	hSpCas9	negative selection	11473905
140800429	140800452	7	-	28162770	MOLM13	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	-0.3893100180563972	[345]	[190]	-2	hSpCas9	negative selection	11473906
140794410	140794433	7	+	28162770	MOLM13	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	0.060844673019265744	[239]	[180]	0	hSpCas9	negative selection	11473907
140924684	140924707	7	-	28162770	HEL	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	1.2422009024166283	[32]	[49]	9	hSpCas9	negative selection	11643264
140924584	140924607	7	+	28162770	HEL	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.36688986919741995	[450]	[223]	-3	hSpCas9	negative selection	11643265
140800358	140800381	7	+	28162770	HEL	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.4734791268764472	[270]	[240]	4	hSpCas9	negative selection	11643266
140783108	140783131	7	+	28162770	HEL	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	1.3741874211989975	[261]	[434]	9	hSpCas9	negative selection	11643267
140924640	140924663	7	-	28162770	HEL	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	0.3581712646169218	[323]	[265]	3	hSpCas9	negative selection	11643268
140924625	140924648	7	-	28162770	HEL	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	1.2311079341647626	[140]	[211]	9	hSpCas9	negative selection	11643269
140834615	140834638	7	-	28162770	HEL	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	-0.3840280775624285	[543]	[266]	-3	hSpCas9	negative selection	11643270
140801443	140801466	7	+	28162770	HEL	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	0.3849410745327104	[164]	[137]	3	hSpCas9	negative selection	11643271
140800429	140800452	7	-	28162770	HEL	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	-0.3693340003002182	[239]	[118]	-3	hSpCas9	negative selection	11643272
140794410	140794433	7	+	28162770	HEL	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	0.17043413204866287	[196]	[141]	1	hSpCas9	negative selection	11643273
140924684	140924707	7	-	28162770	MV411	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-2.7525624492172245	[63]	[7]	-9	hSpCas9	negative selection	11812630
140924584	140924607	7	+	28162770	MV411	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	0.7638770822698323	[308]	[441]	7	hSpCas9	negative selection	11812631
140800358	140800381	7	+	28162770	MV411	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.22112627366692794	[165]	[162]	2	hSpCas9	negative selection	11812632
140783108	140783131	7	+	28162770	MV411	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	0.8921062976281995	[212]	[332]	7	hSpCas9	negative selection	11812633
140924640	140924663	7	-	28162770	MV411	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	0.455644065875912	[218]	[252]	4	hSpCas9	negative selection	11812634
140924625	140924648	7	-	28162770	MV411	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	-0.20712831268270593	[147]	[107]	-1	hSpCas9	negative selection	11812635
140834615	140834638	7	-	28162770	MV411	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	0.06619723611262873	[287]	[253]	0	hSpCas9	negative selection	11812636
140801443	140801466	7	+	28162770	MV411	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.40463914579691795	[142]	[90]	-3	hSpCas9	negative selection	11812637
140800429	140800452	7	-	28162770	MV411	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	-1.141259556317288	[198]	[75]	-6	hSpCas9	negative selection	11812638
140794410	140794433	7	+	28162770	MV411	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	-0.5661493249863434	[173]	[98]	-4	hSpCas9	negative selection	11812639
140924684	140924707	7	-	28162770	MONOMAC1	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-0.15264272770110066	[31]	[32]	-1	hSpCas9	negative selection	11981996
140924584	140924607	7	+	28162770	MONOMAC1	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.5856989309141	[270]	[206]	-5	hSpCas9	negative selection	11981997
140800358	140800381	7	+	28162770	MONOMAC1	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	0.5483903258548485	[135]	[227]	5	hSpCas9	negative selection	11981998
140783108	140783131	7	+	28162770	MONOMAC1	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	0.2761348282040459	[151]	[210]	2	hSpCas9	negative selection	11981999
140924640	140924663	7	-	28162770	MONOMAC1	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-0.1404533186931861	[149]	[155]	-1	hSpCas9	negative selection	11982000
140924625	140924648	7	-	28162770	MONOMAC1	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	-0.3050965929170065	[96]	[89]	-3	hSpCas9	negative selection	11982001
140834615	140834638	7	-	28162770	MONOMAC1	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	0.15597892561190563	[201]	[257]	1	hSpCas9	negative selection	11982002
140801443	140801466	7	+	28162770	MONOMAC1	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	0.26380434183241486	[92]	[127]	2	hSpCas9	negative selection	11982003
140800429	140800452	7	-	28162770	MONOMAC1	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	1.4216350152683777	[140]	[432]	9	hSpCas9	negative selection	11982004
140794410	140794433	7	+	28162770	MONOMAC1	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	-0.2757488230735945	[112]	[106]	-2	hSpCas9	negative selection	11982005
140924684	140924707	7	-	28162770	OCIAML2	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	-0.18522760637991276	[7]	[38]	-1	hSpCas9	negative selection	12151362
140924584	140924607	7	+	28162770	OCIAML2	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	0.6836983211491326	[61]	[551]	6	hSpCas9	negative selection	12151363
140800358	140800381	7	+	28162770	OCIAML2	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.46245589379646107	[43]	[176]	-4	hSpCas9	negative selection	12151364
140783108	140783131	7	+	28162770	OCIAML2	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	0.6576942717333781	[42]	[375]	6	hSpCas9	negative selection	12151365
140924640	140924663	7	-	28162770	OCIAML2	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	0.8156743599144795	[40]	[399]	7	hSpCas9	negative selection	12151366
140924625	140924648	7	-	28162770	OCIAML2	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	-0.3196879271674217	[33]	[150]	-3	hSpCas9	negative selection	12151367
140834615	140834638	7	-	28162770	OCIAML2	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	0.8287361149931094	[57]	[570]	7	hSpCas9	negative selection	12151368
140801443	140801466	7	+	28162770	OCIAML2	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	0.3367250968154428	[25]	[181]	3	hSpCas9	negative selection	12151369
140800429	140800452	7	-	28162770	OCIAML2	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	0.2873973844518746	[33]	[229]	2	hSpCas9	negative selection	12151370
140794410	140794433	7	+	28162770	OCIAML2	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	0.21473457243683258	[36]	[237]	2	hSpCas9	negative selection	12151371
140924684	140924707	7	-	28162770	OCIAML3	viability	AAGATGGCGGCGCTGAGCGGTGG	BRAF	ENSG00000157764	0.5384426556994863	[12]	[56]	5	hSpCas9	negative selection	12320728
140924584	140924607	7	+	28162770	OCIAML3	viability	GTCCGCAGCCGAAGAGGCCGCGG	BRAF	ENSG00000157764	-0.04711318043652657	[127]	[373]	0	hSpCas9	negative selection	12320729
140800358	140800381	7	+	28162770	OCIAML3	viability	ATACCCAATAGAGTCCGAGGCGG	BRAF	ENSG00000157764	-0.8269848123017773	[56]	[96]	-6	hSpCas9	negative selection	12320730
140783108	140783131	7	+	28162770	OCIAML3	viability	TGAGCCAGGTAATGAGGCAGGGG	BRAF	ENSG00000157764	0.9346866407502481	[60]	[351]	7	hSpCas9	negative selection	12320731
140924640	140924663	7	-	28162770	OCIAML3	viability	GGGCCAGGCTCTGTTCAACGGGG	BRAF	ENSG00000157764	-0.5527849775976501	[68]	[141]	-4	hSpCas9	negative selection	12320732
140924625	140924648	7	-	28162770	OCIAML3	viability	CAACGGGGACATGGAGCCCGAGG	BRAF	ENSG00000157764	0.1382965764721802	[30]	[102]	1	hSpCas9	negative selection	12320733
140834615	140834638	7	-	28162770	OCIAML3	viability	TCTTCCTGCCCAACAAACAGAGG	BRAF	ENSG00000157764	0.1907243727727702	[100]	[347]	1	hSpCas9	negative selection	12320734
140801443	140801466	7	+	28162770	OCIAML3	viability	GAACTTCTGTACTACAACGCTGG	BRAF	ENSG00000157764	-0.8794098591864112	[38]	[63]	-6	hSpCas9	negative selection	12320735
140800429	140800452	7	-	28162770	OCIAML3	viability	CCACCCAATACCACAGGAAGAGG	BRAF	ENSG00000157764	-0.29855175679799184	[76]	[188]	-2	hSpCas9	negative selection	12320736
140794410	140794433	7	+	28162770	OCIAML3	viability	GAAGGGCTGTGGAATTGGAATGG	BRAF	ENSG00000157764	0.6935689497724224	[33]	[165]	6	hSpCas9	negative selection	12320737