Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 147372
• Symbol: CCBE1
• Description: collagen and calcium binding EGF domains 1

DataSource: http://genomecrispr.dkfz.de/#!/results/CCBE1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
59439789	59439812	18	-	26472758	Jiyoye	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	-0.3786998131412791	[49]	[28]	-3	hSpCas9	negative selection	24398
59466762	59466785	18	-	26472758	Jiyoye	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	1.3556450808657912	[113]	[219]	7	hSpCas9	negative selection	24399
59439763	59439786	18	+	26472758	Jiyoye	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.9992976737998955	[66]	[100]	6	hSpCas9	negative selection	24400
59466864	59466887	18	-	26472758	Jiyoye	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	0.1255437567947495	[202]	[166]	1	hSpCas9	negative selection	24401
59439550	59439573	18	-	26472758	Jiyoye	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	6.850118877354602	[0]	[86]	9	hSpCas9	negative selection	24402
59469498	59469521	18	-	26472758	Jiyoye	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	1.1089515472097797	[82]	[134]	7	hSpCas9	negative selection	24403
59466806	59466829	18	-	26472758	Jiyoye	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	-2.746629954573162	[88]	[9]	-9	hSpCas9	negative selection	24404
59439789	59439812	18	-	26472758	KBM7	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	1.122717020037434	[136,144]	[107,178]	9	hSpCas9	negative selection	215516
59466762	59466785	18	-	26472758	KBM7	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.056172343027919236	[725,509]	[256,334]	0	hSpCas9	negative selection	215517
59439763	59439786	18	+	26472758	KBM7	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.46259127094262265	[339,145]	[136,164]	5	hSpCas9	negative selection	215518
59466864	59466887	18	-	26472758	KBM7	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	0.8289348227961308	[647,579]	[664,375]	8	hSpCas9	negative selection	215519
59439550	59439573	18	-	26472758	KBM7	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	0.8895232129181395	[144,232]	[124,208]	8	hSpCas9	negative selection	215520
59469498	59469521	18	-	26472758	KBM7	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	1.2447778478926799	[545,514]	[672,519]	9	hSpCas9	negative selection	215521
59466806	59466829	18	-	26472758	KBM7	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	0.625154150005724	[117,178]	[91,126]	6	hSpCas9	negative selection	215522
59439789	59439812	18	-	26472758	Raji	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	0.10738353537359946	[91]	[22]	1	hSpCas9	negative selection	406634
59466762	59466785	18	-	26472758	Raji	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.25835943401492184	[280]	[77]	2	hSpCas9	negative selection	406635
59439763	59439786	18	+	26472758	Raji	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.3086417436207033	[166]	[47]	3	hSpCas9	negative selection	406636
59466864	59466887	18	-	26472758	Raji	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	0.22076533479134208	[317]	[85]	2	hSpCas9	negative selection	406637
59439550	59439573	18	-	26472758	Raji	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	0.07679521554017665	[142]	[34]	0	hSpCas9	negative selection	406638
59469498	59469521	18	-	26472758	Raji	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.3862843466664143	[210]	[63]	3	hSpCas9	negative selection	406639
59466806	59466829	18	-	26472758	Raji	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	-1.2000449898186478	[98]	[9]	-7	hSpCas9	negative selection	406640
59439789	59439812	18	-	26472758	K562	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	1.1878351993000797	[103]	[199]	8	hSpCas9	negative selection	597752
59466762	59466785	18	-	26472758	K562	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.23571903271606143	[498]	[495]	1	hSpCas9	negative selection	597753
59439763	59439786	18	+	26472758	K562	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.19666559621807878	[214]	[207]	1	hSpCas9	negative selection	597754
59466864	59466887	18	-	26472758	K562	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	1.0355038102475396	[585]	[1013]	8	hSpCas9	negative selection	597755
59439550	59439573	18	-	26472758	K562	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	0.8791342635847026	[189]	[294]	7	hSpCas9	negative selection	597756
59469498	59469521	18	-	26472758	K562	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.26762611882777215	[369]	[375]	2	hSpCas9	negative selection	597757
59466806	59466829	18	-	26472758	K562	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	2.137048630149796	[121]	[452]	9	hSpCas9	negative selection	597758
59454850	59454873	18	-	26627737	DLD1	viability	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.3644270081425032	[2171]	[789,978,859]	4	hSpCas9	negative selection	801825
59466763	59466786	18	-	26627737	DLD1	viability	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	0.2799548961851316	[801]	[258,233,401]	3	hSpCas9	negative selection	801826
59469498	59469521	18	-	26627737	DLD1	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	2.162439224819247	[63]	[71,11,168]	9	hSpCas9	negative selection	801827
59480185	59480208	18	-	26627737	DLD1	viability	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.3805724104525898	[401]	[174,219,106]	4	hSpCas9	negative selection	801828
59454850	59454873	18	-	26627737	GBM cells	viability after 5 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.15045264188164964	[1112]	[632,691]	2	hSpCas9	negative selection	884140
59466763	59466786	18	-	26627737	GBM cells	viability after 5 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.2683808705119547	[410]	[211,153]	-4	hSpCas9	negative selection	884141
59469498	59469521	18	-	26627737	GBM cells	viability after 5 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.537185239920988	[91]	[29,37]	-7	hSpCas9	negative selection	884142
59480185	59480208	18	-	26627737	GBM cells	viability after 5 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.25566955832613625	[220]	[122,159]	4	hSpCas9	negative selection	884143
59454850	59454873	18	-	26627737	GBM cells	viability after 13 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.18681881749752982	[1112]	[752,633]	2	hSpCas9	negative selection	966455
59466763	59466786	18	-	26627737	GBM cells	viability after 13 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.11002045081092171	[410]	[215,198]	-1	hSpCas9	negative selection	966456
59469498	59469521	18	-	26627737	GBM cells	viability after 13 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.06122315322089378	[91]	[77,30]	0	hSpCas9	negative selection	966457
59480185	59480208	18	-	26627737	GBM cells	viability after 13 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.8628227695968629	[220]	[286,161]	8	hSpCas9	negative selection	966458
59454850	59454873	18	-	26627737	GBM cells	viability after 21 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.351808626403848	[1112]	[814,731]	3	hSpCas9	negative selection	1048770
59466763	59466786	18	-	26627737	GBM cells	viability after 21 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.034944665431241306	[410]	[230,205]	0	hSpCas9	negative selection	1048771
59469498	59469521	18	-	26627737	GBM cells	viability after 21 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.8955832235219057	[91]	[29,23]	-7	hSpCas9	negative selection	1048772
59480185	59480208	18	-	26627737	GBM cells	viability after 21 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.6686681121290304	[220]	[205,176]	6	hSpCas9	negative selection	1048773
59454850	59454873	18	-	26627737	RPE1	viability after 9 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.43502687752175895	[4258]	[1551,2125]	3	hSpCas9	negative selection	1131085
59466763	59466786	18	-	26627737	RPE1	viability after 9 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.14489854016578196	[1597]	[441,465]	-1	hSpCas9	negative selection	1131086
59469498	59469521	18	-	26627737	RPE1	viability after 9 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.4600983217677854	[328]	[173,99]	3	hSpCas9	negative selection	1131087
59480185	59480208	18	-	26627737	RPE1	viability after 9 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	1.0378549837749818	[460]	[208,408]	6	hSpCas9	negative selection	1131088
59454850	59454873	18	-	26627737	RPE1	viability after 12 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.46950727183737273	[4258]	[1579,1588]	3	hSpCas9	negative selection	1213400
59466763	59466786	18	-	26627737	RPE1	viability after 12 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.37363487526741346	[1597]	[377,281]	-3	hSpCas9	negative selection	1213401
59469498	59469521	18	-	26627737	RPE1	viability after 12 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.21062849314454857	[328]	[128,73]	1	hSpCas9	negative selection	1213402
59480185	59480208	18	-	26627737	RPE1	viability after 12 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	1.2077921193796337	[460]	[288,282]	7	hSpCas9	negative selection	1213403
59454850	59454873	18	-	26627737	RPE1	viability after 15 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.4844921031389906	[4258]	[1848,1527]	3	hSpCas9	negative selection	1295715
59466763	59466786	18	-	26627737	RPE1	viability after 15 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.13507042806042646	[1597]	[431,391]	-1	hSpCas9	negative selection	1295716
59469498	59469521	18	-	26627737	RPE1	viability after 15 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.7921538729565722	[328]	[39,66]	-5	hSpCas9	negative selection	1295717
59480185	59480208	18	-	26627737	RPE1	viability after 15 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.9859463631585319	[460]	[185,327]	6	hSpCas9	negative selection	1295718
59454850	59454873	18	-	26627737	RPE1	viability after 18 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.5901350228775191	[4258]	[1722,1737]	3	hSpCas9	negative selection	1378030
59466763	59466786	18	-	26627737	RPE1	viability after 18 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	0.015267600307591556	[1597]	[401,471]	0	hSpCas9	negative selection	1378031
59469498	59469521	18	-	26627737	RPE1	viability after 18 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.33209389875297535	[328]	[85,53]	-2	hSpCas9	negative selection	1378032
59480185	59480208	18	-	26627737	RPE1	viability after 18 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	1.047361426235883	[460]	[216,299]	6	hSpCas9	negative selection	1378033
59454850	59454873	18	-	26627737	HeLa	viability after 8 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.16389679272228586	[1764]	[1049,979,610]	1	hSpCas9	negative selection	1460345
59466763	59466786	18	-	26627737	HeLa	viability after 8 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.5161788606120977	[1017]	[192,422,288]	-5	hSpCas9	negative selection	1460346
59469498	59469521	18	-	26627737	HeLa	viability after 8 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	1.2992994240067635	[60]	[7,163,14]	8	hSpCas9	negative selection	1460347
59480185	59480208	18	-	26627737	HeLa	viability after 8 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	-0.42417501101655386	[585]	[177,251,140]	-4	hSpCas9	negative selection	1460348
59454850	59454873	18	-	26627737	HeLa	viability after 12 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.4157670562021587	[1764]	[1153,787,1001]	3	hSpCas9	negative selection	1542660
59466763	59466786	18	-	26627737	HeLa	viability after 12 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-1.1683446191412348	[1017]	[94,185,277]	-8	hSpCas9	negative selection	1542661
59469498	59469521	18	-	26627737	HeLa	viability after 12 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.5944891365301523	[60]	[27,55,27]	5	hSpCas9	negative selection	1542662
59480185	59480208	18	-	26627737	HeLa	viability after 12 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	-0.7204491800245234	[585]	[304,66,81]	-6	hSpCas9	negative selection	1542663
59454850	59454873	18	-	26627737	HeLa	viability after 15 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.5226561054964192	[1764]	[1100,1443,510]	4	hSpCas9	negative selection	1624975
59466763	59466786	18	-	26627737	HeLa	viability after 15 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.8313312416806431	[1017]	[141,166,403]	-6	hSpCas9	negative selection	1624976
59469498	59469521	18	-	26627737	HeLa	viability after 15 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.9856638517244589	[60]	[46,45,54]	7	hSpCas9	negative selection	1624977
59480185	59480208	18	-	26627737	HeLa	viability after 15 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	-0.034212459570665876	[585]	[247,310,131]	0	hSpCas9	negative selection	1624978
59454850	59454873	18	-	26627737	HeLa	viability after 18 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.5322018995704094	[1764]	[746,1201,510]	4	hSpCas9	negative selection	1707290
59466763	59466786	18	-	26627737	HeLa	viability after 18 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.7926907301461903	[1017]	[110,133,403]	-6	hSpCas9	negative selection	1707291
59469498	59469521	18	-	26627737	HeLa	viability after 18 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	1.044667581113101	[60]	[37,34,54]	7	hSpCas9	negative selection	1707292
59480185	59480208	18	-	26627737	HeLa	viability after 18 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	-0.017162757575352128	[585]	[176,250,131]	0	hSpCas9	negative selection	1707293
59454850	59454873	18	-	26627737	HCT116	viability after 6 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.0346655736594641	[2125]	[507,250]	0	hSpCas9	negative selection	1789605
59466763	59466786	18	-	26627737	HCT116	viability after 6 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	1.2950117308164595	[900]	[295,375]	7	hSpCas9	negative selection	1789606
59469498	59469521	18	-	26627737	HCT116	viability after 6 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.4443086738931872	[184]	[41,9]	-3	hSpCas9	negative selection	1789607
59480185	59480208	18	-	26627737	HCT116	viability after 6 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	-2.003044751258813	[624]	[19,26]	-8	hSpCas9	negative selection	1789608
59454850	59454873	18	-	26627737	HCT116	viability after 8 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.11203925650549662	[1373]	[707,861,881]	1	hSpCas9	negative selection	1871920
59466763	59466786	18	-	26627737	HCT116	viability after 8 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.0033512976684881846	[522]	[318,246,296]	0	hSpCas9	negative selection	1871921
59469498	59469521	18	-	26627737	HCT116	viability after 8 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.22846869944433434	[79]	[32,19,100]	2	hSpCas9	negative selection	1871922
59480185	59480208	18	-	26627737	HCT116	viability after 8 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.13649777442060476	[296]	[164,159,213]	1	hSpCas9	negative selection	1871923
59454850	59454873	18	-	26627737	HCT116	viability after 9 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.04213426257689323	[2125]	[655,527]	0	hSpCas9	negative selection	1954235
59466763	59466786	18	-	26627737	HCT116	viability after 9 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	0.31378205555016914	[900]	[312,287]	2	hSpCas9	negative selection	1954236
59469498	59469521	18	-	26627737	HCT116	viability after 9 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.7444096284681863	[184]	[0,51]	-5	hSpCas9	negative selection	1954237
59480185	59480208	18	-	26627737	HCT116	viability after 9 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	-2.239764614353938	[624]	[55,18]	-9	hSpCas9	negative selection	1954238
59454850	59454873	18	-	26627737	HCT116	viability after 12 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.2103683016752642	[1373]	[803,874,830]	2	hSpCas9	negative selection	2036550
59466763	59466786	18	-	26627737	HCT116	viability after 12 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.13278870926352326	[522]	[303,276,166]	-1	hSpCas9	negative selection	2036551
59469498	59469521	18	-	26627737	HCT116	viability after 12 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.07813232524156	[79]	[49,56,11]	-1	hSpCas9	negative selection	2036552
59480185	59480208	18	-	26627737	HCT116	viability after 12 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	-0.08201013434718508	[296]	[121,204,118]	-1	hSpCas9	negative selection	2036553
59454850	59454873	18	-	26627737	HCT116	viability after 15 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.3133641498924882	[1373]	[1201,827,938]	3	hSpCas9	negative selection	2118865
59466763	59466786	18	-	26627737	HCT116	viability after 15 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.15166553161293217	[522]	[409,135,281]	-1	hSpCas9	negative selection	2118866
59469498	59469521	18	-	26627737	HCT116	viability after 15 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.12865361110923357	[79]	[25,45,51]	-1	hSpCas9	negative selection	2118867
59480185	59480208	18	-	26627737	HCT116	viability after 15 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	-0.4797174056260951	[296]	[112,145,106]	-5	hSpCas9	negative selection	2118868
59454850	59454873	18	-	26627737	HCT116	viability after 18 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.6956081704060506	[1373]	[1116,1079,1027]	6	hSpCas9	negative selection	2201180
59466763	59466786	18	-	26627737	HCT116	viability after 18 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.014684353190024924	[522]	[238,364,133]	0	hSpCas9	negative selection	2201181
59469498	59469521	18	-	26627737	HCT116	viability after 18 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.8005596710824048	[79]	[5,16,44]	-6	hSpCas9	negative selection	2201182
59480185	59480208	18	-	26627737	HCT116	viability after 18 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.3626701912333443	[296]	[271,61,229]	3	hSpCas9	negative selection	2201183
59625378	59625401	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGCGCAGTGGCGCGATCTTGG	CCBE1	ENSG00000183287	-0.814608194487327	[84,35]	[10,2]	-4	dCas9-VP64	positive selection	2398692
59601059	59601082	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCACTCTGTCTCCCAGGCTGG	CCBE1	ENSG00000183287	-0.22926698104333687	[120,197]	[15,43]	-1	dCas9-VP64	positive selection	2418693
59442651	59442674	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAATCTCTGCCTCCCAG	CCBE1	ENSG00000183287	0.009160240507729789	[175,457]	[15,128]	0	dCas9-VP64	positive selection	2425902
59691443	59691466	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCCCAGGCTGGAGTGCAGTGG	CCBE1	ENSG00000183287	0.9977856233970179	[9,4]	[4,0]	4	dCas9-VP64	positive selection	2435978
59614275	59614298	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCATCGTGCCTGG	CCBE1	ENSG00000183287	-2.3680687732448105	[443,16]	[15,1]	-9	dCas9-VP64	positive selection	2440326
59625386	59625409	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCACTGCGCTCCAGCCTGGG	CCBE1	ENSG00000183287	-0.692868363357688	[238,335]	[46,29]	-4	dCas9-VP64	positive selection	2440987
59450606	59450629	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCTGCCTCCCAG	CCBE1	ENSG00000183287	0.3736894149735144	[619,564]	[67,277]	1	dCas9-VP64	positive selection	2443997
59589763	59589786	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCGCTCTGTCGCCCTGG	CCBE1	ENSG00000183287	-0.5315818005101806	[14,129]	[5,15]	-3	dCas9-VP64	positive selection	2444290
59569758	59569781	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCTCAGCTACTTAG	CCBE1	ENSG00000183287	-0.32009396436001514	[73,465]	[65,28]	-1	dCas9-VP64	positive selection	2454564
59625378	59625401	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGCGCAGTGGCGCGATCTTGG	CCBE1	ENSG00000183287	-1.763356426520778	[237,164]	[17,19]	-9	dCas9-VP64	positive selection	2493947
59601059	59601082	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCACTCTGTCTCCCAGGCTGG	CCBE1	ENSG00000183287	-0.22012594312438807	[153,72]	[52,11]	-2	dCas9-VP64	positive selection	2513948
59442651	59442674	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAATCTCTGCCTCCCAG	CCBE1	ENSG00000183287	0.1118552473866502	[131,312]	[53,99]	0	dCas9-VP64	positive selection	2521157
59691443	59691466	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCCCAGGCTGGAGTGCAGTGG	CCBE1	ENSG00000183287	-0.1814090993543942	[50,40]	[18,6]	-2	dCas9-VP64	positive selection	2531233
59614275	59614298	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCATCGTGCCTGG	CCBE1	ENSG00000183287	0.42142368151358683	[69,54]	[32,21]	3	dCas9-VP64	positive selection	2535581
59625386	59625409	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCACTGCGCTCCAGCCTGGG	CCBE1	ENSG00000183287	0.15562510186866851	[37,63]	[19,15]	1	dCas9-VP64	positive selection	2536242
59450606	59450629	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCTGCCTCCCAG	CCBE1	ENSG00000183287	2.2699980135687987	[309,268]	[879,61]	8	dCas9-VP64	positive selection	2539252
59589763	59589786	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCGCTCTGTCGCCCTGG	CCBE1	ENSG00000183287	0.35722745049512583	[51,32]	[17,15]	3	dCas9-VP64	positive selection	2539545
59569758	59569781	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCTCAGCTACTTAG	CCBE1	ENSG00000183287	-0.35714226545986627	[161,80]	[51,10]	-4	dCas9-VP64	positive selection	2549819
59469587	59469610	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.3906913372111662	[3,3]	[4,3]	7	hSpCas9	positive selection	2976673
59466800	59466823	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCCTTCCCGGCACTCGCAGCGG	CCBE1	ENSG00000183287	0.37473539952172513	[3,3]	[4,3]	7	hSpCas9	positive selection	2976674
59466763	59466786	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	0.2883650068717941	[3,2]	[2,3]	6	hSpCas9	positive selection	2976675
59469587	59469610	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.4359123318024128	[3,3]	[2,0]	-6	hSpCas9	positive selection	3044531
59466800	59466823	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCCTTCCCGGCACTCGCAGCGG	CCBE1	ENSG00000183287	0.4303654946737812	[3,3]	[2,3]	7	hSpCas9	positive selection	3044532
59466763	59466786	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.46687774771019436	[3,3]	[3,0]	-6	hSpCas9	positive selection	3044533
59469587	59469610	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.9006944397027659	[73,89]	[0,0]	4	hSpCas9	positive selection	3341282
59469473	59469496	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.4499712893882311	[111,111]	[0,0]	2	hSpCas9	positive selection	3360526
59469587	59469610	18	-	26780180	HT29	viability (Avana library 4 designs)	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.224372160666488	[]	[]	0	hSpCas9	negative selection	3412943
59466799	59466822	18	+	26780180	HT29	viability (Avana library 4 designs)	AGCCTTCCCGGCACTCGCAGCGG	CCBE1	ENSG00000183287	0.670764739696685	[]	[]	2	hSpCas9	negative selection	3412944
59466763	59466786	18	-	26780180	HT29	viability (Avana library 4 designs)	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	1.21672631782053	[]	[]	5	hSpCas9	negative selection	3412945
59466763	59466786	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.100379149519023	[]	[]	0	hSpCas9	negative selection	3488737
59469587	59469610	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	4.18011034515854	[]	[]	7	hSpCas9	negative selection	3488738
59466799	59466822	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCCTTCCCGGCACTCGCAGCGG	CCBE1	ENSG00000183287	3.79452781717147	[]	[]	6	hSpCas9	negative selection	3488739
59466779	59466802	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTACATCCGGGAAGATGATGGG	CCBE1	ENSG00000183287	1.97375999841129	[]	[]	3	hSpCas9	negative selection	3488740
59469498	59469521	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	4.01800339726059	[]	[]	6	hSpCas9	negative selection	3488741
59466763	59466786	18	-	26780180	A375	viability (Avana lentiGuide)	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.409639190430282	[]	[]	0	hSpCas9	negative selection	3597396
59469587	59469610	18	-	26780180	A375	viability (Avana lentiGuide)	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-1.08979342882029	[]	[]	-2	hSpCas9	negative selection	3597397
59466799	59466822	18	+	26780180	A375	viability (Avana lentiGuide)	AGCCTTCCCGGCACTCGCAGCGG	CCBE1	ENSG00000183287	1.73425892484311	[]	[]	2	hSpCas9	negative selection	3597398
59466779	59466802	18	-	26780180	A375	viability (Avana lentiGuide)	GCTACATCCGGGAAGATGATGGG	CCBE1	ENSG00000183287	-2.79523845481105	[]	[]	-5	hSpCas9	negative selection	3597399
59469498	59469521	18	-	26780180	A375	viability (Avana lentiGuide)	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-3.82193807529315	[]	[]	-6	hSpCas9	negative selection	3597400
59466763	59466786	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	0.14673611622985444	[5]	[6,5]	4	hSpCas9	positive selection	3706055
59469587	59469610	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.03714589645579024	[5]	[6,3]	0	hSpCas9	positive selection	3706056
59466799	59466822	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCCTTCCCGGCACTCGCAGCGG	CCBE1	ENSG00000183287	0.013275652062233068	[4]	[5,3]	0	hSpCas9	positive selection	3706057
59466779	59466802	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTACATCCGGGAAGATGATGGG	CCBE1	ENSG00000183287	0.24551416200192788	[5]	[6,5]	7	hSpCas9	positive selection	3706058
59469498	59469521	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.34430746667429324	[4]	[5,5]	8	hSpCas9	positive selection	3706059
59466763	59466786	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	0.3865788788289676	[4]	[5,4]	9	hSpCas9	positive selection	3814662
59469587	59469610	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.21891273643670725	[5]	[4,3]	-3	hSpCas9	positive selection	3814663
59466799	59466822	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCCTTCCCGGCACTCGCAGCGG	CCBE1	ENSG00000183287	0.03690044769115869	[5]	[3,5]	0	hSpCas9	positive selection	3814664
59466779	59466802	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTACATCCGGGAAGATGATGGG	CCBE1	ENSG00000183287	0.28133786358947555	[5]	[6,5]	7	hSpCas9	positive selection	3814665
59469498	59469521	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.40990325231162605	[5]	[4,1]	-5	hSpCas9	positive selection	3814666
59469587	59469610	18	-	26780180	A375	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	1.35796193852562	[]	[]	7	hSpCas9	negative selection	3922846
59469473	59469496	18	-	26780180	A375	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.877480533285375	[]	[]	3	hSpCas9	negative selection	3922847
59469587	59469610	18	-	26780180	HT29	viability (GeCKOv2 library)	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	1.23751871704838	[]	[]	6	hSpCas9	negative selection	4030812
59469473	59469496	18	-	26780180	HT29	viability (GeCKOv2 library)	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	1.35545757271637	[]	[]	7	hSpCas9	negative selection	4030813
59469587	59469610	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.57402386307892	[2]	[1,0]	-8	hSpCas9	positive selection	4261192
59469473	59469496	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	-0.18262269058006003	[2]	[2,0]	-4	hSpCas9	positive selection	4325471
59466762	59466784	18	-	27760321	OCIAML3	viability	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	-0.8994374905149671	[3,0]	[0,0]	-7	hSpCas9	negative selection	4386077
59466791	59466813	18	-	27760321	OCIAML3	viability	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	-0.01908370005593052	[323,277]	[238,221]	0	hSpCas9	negative selection	4386078
59469510	59469532	18	-	27760321	OCIAML3	viability	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	-0.8087989391504334	[331,258]	[173,74]	-6	hSpCas9	negative selection	4386079
59466762	59466784	18	-	27760321	OCIAML2	viability	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	-0.9481828557800158	[3,0]	[0,0]	-7	hSpCas9	negative selection	4469540
59466791	59466813	18	-	27760321	OCIAML2	viability	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	0.19678526903272753	[323,277]	[241,325]	2	hSpCas9	negative selection	4469541
59469510	59469532	18	-	27760321	OCIAML2	viability	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	0.307886974588547	[331,258]	[226,381]	4	hSpCas9	negative selection	4469542
59466762	59466784	18	-	27760321	MV411	viability	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	-0.6543589216002852	[3,0]	[0,0]	-4	hSpCas9	negative selection	4553003
59466791	59466813	18	-	27760321	MV411	viability	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	1.583216854958688	[323,277]	[823,246]	9	hSpCas9	negative selection	4553004
59469510	59469532	18	-	27760321	MV411	viability	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	-0.19896919125681756	[331,258]	[65,322]	-1	hSpCas9	negative selection	4553005
59466762	59466784	18	-	27760321	HL60	viability	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	-0.9622290833944218	[3,0]	[0,0]	-7	hSpCas9	negative selection	4636466
59466791	59466813	18	-	27760321	HL60	viability	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	-0.5502151422265859	[323,277]	[147,187]	-5	hSpCas9	negative selection	4636467
59469510	59469532	18	-	27760321	HL60	viability	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	-0.8494093950068923	[331,258]	[167,95]	-7	hSpCas9	negative selection	4636468
59466762	59466784	18	-	27760321	HT1080	viability	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4719929
59466791	59466813	18	-	27760321	HT1080	viability	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	-0.3292760183993316	[277,216]	[77,78]	-1	hSpCas9	negative selection	4719930
59469510	59469532	18	-	27760321	HT1080	viability	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	0.41077599363646317	[258,201]	[133,108]	2	hSpCas9	negative selection	4719931
59466762	59466784	18	-	27760321	HT29	viability after 7 days	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	1.6039964213764337	[0,0]	[10,0,0]	9	hSpCas9	negative selection	4803392
59466791	59466813	18	-	27760321	HT29	viability after 7 days	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	0.576702522696175	[277,216]	[501,576,351]	8	hSpCas9	negative selection	4803393
59469510	59469532	18	-	27760321	HT29	viability after 7 days	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	0.2879901298719598	[258,201]	[384,333,368]	4	hSpCas9	negative selection	4803394
59466762	59466784	18	-	27760321	HT29	viability after 25 days	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	2.8852826245147725	[0,0]	[0,0,25]	9	hSpCas9	negative selection	4886855
59466791	59466813	18	-	27760321	HT29	viability after 25 days	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	0.5924975988396696	[277,216]	[458,380,437]	6	hSpCas9	negative selection	4886856
59469510	59469532	18	-	27760321	HT29	viability after 25 days	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	-0.026654554234815886	[258,201]	[198,313,266]	0	hSpCas9	negative selection	4886857
59466762	59466784	18	-	27760321	HT29	viability after 22 days	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	3.8352478561427503	[0,0]	[0,0,48]	9	hSpCas9	negative selection	4970318
59466791	59466813	18	-	27760321	HT29	viability after 22 days	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	0.7352264153389831	[277,216]	[633,378,410]	8	hSpCas9	negative selection	4970319
59469510	59469532	18	-	27760321	HT29	viability after 22 days	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	0.053992643818619235	[258,201]	[279,351,196]	0	hSpCas9	negative selection	4970320
59466762	59466784	18	-	27760321	HT29	viability after 19 days	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5053781
59466791	59466813	18	-	27760321	HT29	viability after 19 days	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	0.5783506823039515	[277,216]	[362,517,381]	6	hSpCas9	negative selection	5053782
59469510	59469532	18	-	27760321	HT29	viability after 19 days	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	-0.41152593521814307	[258,201]	[310,197,100]	-4	hSpCas9	negative selection	5053783
59466762	59466784	18	-	27760321	HT29	viability after 16 days	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.5099320058880714	[0,0]	[2,0,0]	6	hSpCas9	negative selection	5137244
59466791	59466813	18	-	27760321	HT29	viability after 16 days	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	0.39138357497176723	[277,216]	[452,402,240]	4	hSpCas9	negative selection	5137245
59469510	59469532	18	-	27760321	HT29	viability after 16 days	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	0.10776894038273044	[258,201]	[317,291,226]	1	hSpCas9	negative selection	5137246
59466762	59466784	18	-	27760321	HT29	viability after 13 days	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	2.8131741604529674	[0,0]	[0,0,21]	9	hSpCas9	negative selection	5220707
59466791	59466813	18	-	27760321	HT29	viability after 13 days	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	0.8749224120473358	[277,216]	[632,515,435]	9	hSpCas9	negative selection	5220708
59469510	59469532	18	-	27760321	HT29	viability after 13 days	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	0.04573145651676058	[258,201]	[334,287,208]	0	hSpCas9	negative selection	5220709
59466762	59466784	18	-	27760321	HT29	viability after 10 days	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	3.8872862439957068	[0,0]	[0,0,52]	9	hSpCas9	negative selection	5304170
59466791	59466813	18	-	27760321	HT29	viability after 10 days	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	0.5154986292851755	[277,216]	[516,364,440]	7	hSpCas9	negative selection	5304171
59469510	59469532	18	-	27760321	HT29	viability after 10 days	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	0.05324385982388624	[258,201]	[237,430,231]	0	hSpCas9	negative selection	5304172
59466762	59466784	18	-	27760321	MOLM13	viability	ATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	-0.4283021087726899	[3,0]	[0,0]	-3	hSpCas9	negative selection	5387633
59466791	59466813	18	-	27760321	MOLM13	viability	GTGCCGGGAAGGCTACATCCGG	CCBE1	ENSG00000183287	1.5389539107163528	[323,277]	[955,96]	9	hSpCas9	negative selection	5387634
59469510	59469532	18	-	27760321	MOLM13	viability	TCCGGGATACCGATATGACCGG	CCBE1	ENSG00000183287	-0.7987268145754073	[331,258]	[85,102]	-5	hSpCas9	negative selection	5387635
59469587	59469610	18	-	27260156	BXPC3	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.11764991720378348	[256]	[276,183,207,329]	-3	hSpCas9	negative selection	5533652
59469473	59469496	18	-	27260156	BXPC3	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.09927862724786185	[213]	[205,215,237,310]	2	hSpCas9	negative selection	5597931
59469587	59469610	18	-	27260156	A673	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.04644532706145432	[256]	[420,165,358,344]	1	hSpCas9	negative selection	5654903
59469473	59469496	18	-	27260156	A673	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.17102796493494932	[213]	[337,292,264,264]	4	hSpCas9	negative selection	5719182
59469587	59469610	18	-	27260156	A375	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.3919635434983112	[256]	[161,378,168,224]	-5	hSpCas9	negative selection	5776154
59469473	59469496	18	-	27260156	A375	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.43414039303088714	[213]	[314,471,353,238]	6	hSpCas9	negative selection	5840433
59469587	59469610	18	-	27260156	COLO741	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.0745724846078516	[256]	[348,278,309]	-2	hSpCas9	negative selection	5897405
59469473	59469496	18	-	27260156	COLO741	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	-0.46267392451860756	[213]	[141,247,199]	-7	hSpCas9	negative selection	5961684
59469587	59469610	18	-	27260156	CAL120	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.634256067803222	[256]	[288,161,179]	-7	hSpCas9	negative selection	6018656
59469473	59469496	18	-	27260156	CAL120	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.21383353014248385	[213]	[369,166,396]	3	hSpCas9	negative selection	6082935
59469587	59469610	18	-	27260156	CADOES1	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.05358963157975427	[256]	[188,180,300,250]	-1	hSpCas9	negative selection	6139907
59469473	59469496	18	-	27260156	CADOES1	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	-0.02029261649206271	[213]	[228,147,257,147]	0	hSpCas9	negative selection	6204186
59469587	59469610	18	-	27260156	EWS502	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.10313677717659564	[256]	[166,192,364,305]	-2	hSpCas9	negative selection	6261158
59469473	59469496	18	-	27260156	EWS502	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.15814856012176515	[213]	[250,230,247,283]	2	hSpCas9	negative selection	6325437
59469587	59469610	18	-	27260156	EW8	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.0812735086315931	[256]	[258,155,181,293]	1	hSpCas9	negative selection	6382409
59469473	59469496	18	-	27260156	EW8	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	-0.025298699885163645	[213]	[256,169,139,128]	0	hSpCas9	negative selection	6446688
59469587	59469610	18	-	27260156	CORL105	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.4004794802437376	[256]	[211,182,216,297]	-6	hSpCas9	negative selection	6503660
59469473	59469496	18	-	27260156	CORL105	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.06033314260888578	[213]	[238,278,281,246]	1	hSpCas9	negative selection	6567939
59469587	59469610	18	-	27260156	HS294T	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.03133601876973746	[256]	[65,122,100,121]	0	hSpCas9	negative selection	6624911
59469473	59469496	18	-	27260156	HS294T	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.24212950515005105	[213]	[75,134,47,139]	3	hSpCas9	negative selection	6689190
59469587	59469610	18	-	27260156	HCC44	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.07225235513939188	[256]	[471,194,276,191]	-1	hSpCas9	negative selection	6746162
59469473	59469496	18	-	27260156	HCC44	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.5890852387306316	[213]	[350,426,337,323]	8	hSpCas9	negative selection	6810441
59469587	59469610	18	-	27260156	G402	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.49926325020057594	[256]	[392,237,75,205]	-6	hSpCas9	negative selection	6867413
59469473	59469496	18	-	27260156	G402	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	-0.03028512845902087	[213]	[206,377,204,232]	0	hSpCas9	negative selection	6931692
59469587	59469610	18	-	27260156	L33	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.2338004675526194	[256]	[289,101,193,360]	5	hSpCas9	negative selection	6988664
59469473	59469496	18	-	27260156	L33	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.008836609198189072	[213]	[228,92,154,158]	0	hSpCas9	negative selection	7052943
59469587	59469610	18	-	27260156	K562	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.4817964367227169	[256]	[269,184,105,107]	-5	hSpCas9	negative selection	7109915
59469473	59469496	18	-	27260156	K562	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.7460213832006584	[213]	[375,436,136,331]	8	hSpCas9	negative selection	7174194
59469587	59469610	18	-	27260156	HT29	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.08375692556275993	[256]	[304,376,320,321]	1	hSpCas9	negative selection	7231166
59469473	59469496	18	-	27260156	HT29	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.19641498090094844	[213]	[352,330,329,195]	4	hSpCas9	negative selection	7295445
59469587	59469610	18	-	27260156	MHHES1	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.12663469242646774	[256]	[370,237,403,256]	2	hSpCas9	negative selection	7352417
59469473	59469496	18	-	27260156	MHHES1	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.5511914362344522	[213]	[536,295,435,190]	8	hSpCas9	negative selection	7416696
59469587	59469610	18	-	27260156	MEWO	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.1651424264159853	[256]	[222,209,366]	3	hSpCas9	negative selection	7473668
59469473	59469496	18	-	27260156	MEWO	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.4404933899577299	[213]	[356,181,292]	8	hSpCas9	negative selection	7537947
59469587	59469610	18	-	27260156	LNCAPCLONEFGC	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.40564938520756055	[256]	[148,156,238,168]	-6	hSpCas9	negative selection	7594919
59469473	59469496	18	-	27260156	LNCAPCLONEFGC	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.1559090409288867	[213]	[230,145,275,223]	2	hSpCas9	negative selection	7659198
59469587	59469610	18	-	27260156	PANC0327	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.2758586634170147	[256]	[141,226,379,351]	4	hSpCas9	negative selection	7716170
59469473	59469496	18	-	27260156	PANC0327	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	-0.27214150302526985	[213]	[207,132,183,111]	-4	hSpCas9	negative selection	7780449
59469587	59469610	18	-	27260156	NCIH2009	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.4497883007665455	[256]	[449,350,663]	6	hSpCas9	negative selection	7837421
59469473	59469496	18	-	27260156	NCIH2009	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	-0.2380560508493923	[213]	[287,193,285]	-3	hSpCas9	negative selection	7901700
59469587	59469610	18	-	27260156	NCIH1373	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.5219024188233797	[256]	[379,502,452,76]	5	hSpCas9	negative selection	7958672
59469473	59469496	18	-	27260156	NCIH1373	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	-0.22467217341544932	[213]	[344,173,223,24]	-2	hSpCas9	negative selection	8022951
59469587	59469610	18	-	27260156	PATU8902	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.2270185432710865	[256]	[191,722,348,431]	2	hSpCas9	negative selection	8079923
59469473	59469496	18	-	27260156	PATU8902	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.46853860811868775	[213]	[425,355,289,631]	5	hSpCas9	negative selection	8144202
59469587	59469610	18	-	27260156	PANC1	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.17156897374820357	[256]	[226,248,259,253]	2	hSpCas9	negative selection	8201174
59469473	59469496	18	-	27260156	PANC1	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	-0.009490628417131886	[213]	[157,249,246,100]	0	hSpCas9	negative selection	8265453
59469587	59469610	18	-	27260156	PANC0813	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.5521593085575963	[256]	[454,273,516,520]	8	hSpCas9	negative selection	8322425
59469473	59469496	18	-	27260156	PANC0813	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.49827206041305105	[213]	[371,235,495,319]	7	hSpCas9	negative selection	8386704
59469587	59469610	18	-	27260156	RDES	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.05138233745501075	[256]	[160,358,388,240]	-1	hSpCas9	negative selection	8443676
59469473	59469496	18	-	27260156	RDES	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.13637791454448622	[213]	[280,251,259,279]	2	hSpCas9	negative selection	8507955
59469587	59469610	18	-	27260156	PC3	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.39032493806382595	[256]	[108,210,254,251]	-7	hSpCas9	negative selection	8564927
59469473	59469496	18	-	27260156	PC3	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.3928574827787523	[213]	[131,491,353,196]	8	hSpCas9	negative selection	8629206
59469587	59469610	18	-	27260156	PATU8988T	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.2108564717044047	[256]	[240,287,155,177]	-4	hSpCas9	negative selection	8686178
59469473	59469496	18	-	27260156	PATU8988T	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.24983881678774156	[213]	[178,166,188,458]	4	hSpCas9	negative selection	8750457
59469587	59469610	18	-	27260156	T47D	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	-0.125450385918629	[256]	[279,273,287,254]	-3	hSpCas9	negative selection	8807429
59469473	59469496	18	-	27260156	T47D	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.12926565338992257	[213]	[236,355,259,228]	2	hSpCas9	negative selection	8871708
59469587	59469610	18	-	27260156	SU8686	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.5323130775075673	[256]	[307,328,433,422]	8	hSpCas9	negative selection	8928680
59469473	59469496	18	-	27260156	SU8686	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.5912870386463875	[213]	[206,308,348,446]	8	hSpCas9	negative selection	8992959
59469587	59469610	18	-	27260156	SKES1	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.023515023848716177	[256]	[272,372,177,234]	0	hSpCas9	negative selection	9049931
59469473	59469496	18	-	27260156	SKES1	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	-0.17030171962808138	[213]	[200,139,200,207]	-4	hSpCas9	negative selection	9114210
59469587	59469610	18	-	27260156	TOV112D	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.1578571875176985	[256]	[281,254,285,315]	3	hSpCas9	negative selection	9171182
59469473	59469496	18	-	27260156	TOV112D	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.3239672148773797	[213]	[162,509,241,209]	6	hSpCas9	negative selection	9235461
59469587	59469610	18	-	27260156	TC71	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.16999883277427486	[256]	[361,259,223,400]	4	hSpCas9	negative selection	9292433
59469473	59469496	18	-	27260156	TC71	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.026436136419233813	[213]	[309,162,226,232]	0	hSpCas9	negative selection	9356712
59469587	59469610	18	-	27260156	TC32	viability	AGATTACGACGTTTGTGCCGAGG	CCBE1	ENSG00000183287	0.3675913798161655	[256]	[319,203,367,389]	6	hSpCas9	negative selection	9413684
59469473	59469496	18	-	27260156	TC32	viability	GCGGGAGAAGCCATACTGTCTGG	CCBE1	ENSG00000183287	0.20547602336250048	[213]	[261,174,211,280]	4	hSpCas9	negative selection	9477963
59454850	59454873	18	-	27869803	HPAFII	viability after 27 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.9058308709852483	[1202]	[1070,1279,NaN]	7	hSpCas9	negative selection	9564861
59466763	59466786	18	-	27869803	HPAFII	viability after 27 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	0.6973083759341775	[394]	[405,278,NaN]	5	hSpCas9	negative selection	9564862
59469498	59469521	18	-	27869803	HPAFII	viability after 27 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.23368358210138318	[84]	[87,22,NaN]	1	hSpCas9	negative selection	9564863
59480185	59480208	18	-	27869803	HPAFII	viability after 27 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.5077737109489877	[201]	[222,90,NaN]	4	hSpCas9	negative selection	9564864
59454850	59454873	18	-	27869803	HPAFII	viability after 15 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.6106479297307525	[1202]	[2887,1405,NaN]	7	hSpCas9	negative selection	9647310
59466763	59466786	18	-	27869803	HPAFII	viability after 15 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	0.12300904181890837	[394]	[658,339,NaN]	1	hSpCas9	negative selection	9647311
59469498	59469521	18	-	27869803	HPAFII	viability after 15 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.8780989607558449	[84]	[82,28,NaN]	-7	hSpCas9	negative selection	9647312
59480185	59480208	18	-	27869803	HPAFII	viability after 15 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.02126949954687235	[201]	[252,199,NaN]	0	hSpCas9	negative selection	9647313
59454850	59454873	18	-	27869803	ASPC1	viability after 36 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.12023977591789592	[2711]	[1279,1416,533]	1	hSpCas9	negative selection	9729759
59466763	59466786	18	-	27869803	ASPC1	viability after 36 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	-0.4231589477643627	[1086]	[324,425,136]	-4	hSpCas9	negative selection	9729760
59469498	59469521	18	-	27869803	ASPC1	viability after 36 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.12771116186817633	[173]	[135,10,33]	-1	hSpCas9	negative selection	9729761
59480185	59480208	18	-	27869803	ASPC1	viability after 36 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.8859387037853896	[491]	[378,233,336]	8	hSpCas9	negative selection	9729762
59454850	59454873	18	-	27869803	PATU8988S	viability after 35 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.8157749268783092	[2120]	[1572,1433,NaN]	8	hSpCas9	negative selection	9812208
59466763	59466786	18	-	27869803	PATU8988S	viability after 35 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	0.5436721239027635	[801]	[399,541,NaN]	6	hSpCas9	negative selection	9812209
59469498	59469521	18	-	27869803	PATU8988S	viability after 35 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	1.8498627332286341	[208]	[268,337,NaN]	9	hSpCas9	negative selection	9812210
59480185	59480208	18	-	27869803	PATU8988S	viability after 35 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	1.257772705025034	[361]	[188,508,NaN]	9	hSpCas9	negative selection	9812211
59454850	59454873	18	-	27869803	PATU8988S	viability after 31 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.698661000568255	[2120]	[1303,1459,NaN]	7	hSpCas9	negative selection	9894657
59466763	59466786	18	-	27869803	PATU8988S	viability after 31 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	0.3252347848750695	[801]	[291,538,NaN]	4	hSpCas9	negative selection	9894658
59469498	59469521	18	-	27869803	PATU8988S	viability after 31 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	1.6372041295352537	[208]	[216,312,NaN]	9	hSpCas9	negative selection	9894659
59480185	59480208	18	-	27869803	PATU8988S	viability after 31 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.983756240894851	[361]	[178,420,NaN]	9	hSpCas9	negative selection	9894660
59454850	59454873	18	-	27869803	HPAFII	viability after 35 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.9791039388879974	[1202]	[573,1905,NaN]	6	hSpCas9	negative selection	9977106
59466763	59466786	18	-	27869803	HPAFII	viability after 35 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	1.0441115302760196	[394]	[528,280,NaN]	7	hSpCas9	negative selection	9977107
59469498	59469521	18	-	27869803	HPAFII	viability after 35 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	1.1196225702849874	[84]	[156,21,NaN]	7	hSpCas9	negative selection	9977108
59480185	59480208	18	-	27869803	HPAFII	viability after 35 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.4532008177001724	[201]	[147,130,NaN]	3	hSpCas9	negative selection	9977109
59454850	59454873	18	-	27869803	HPAFII	viability after 31 days	CGTGCTGCAGCTGAAGCAAAAGG	CCBE1	ENSG00000183287	0.7579452440756369	[1202]	[833,1476,NaN]	5	hSpCas9	negative selection	10059555
59466763	59466786	18	-	27869803	HPAFII	viability after 31 days	TGATGGGAAGACATGTACCAGGG	CCBE1	ENSG00000183287	0.6236153385812088	[394]	[431,242,NaN]	4	hSpCas9	negative selection	10059556
59469498	59469521	18	-	27869803	HPAFII	viability after 31 days	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.8096578099227718	[84]	[141,19,NaN]	6	hSpCas9	negative selection	10059557
59480185	59480208	18	-	27869803	HPAFII	viability after 31 days	CTTGGACAATGCATCCCAGAAGG	CCBE1	ENSG00000183287	0.21086216845352806	[201]	[146,113,NaN]	1	hSpCas9	negative selection	10059558
59439789	59439812	18	-	28162770	P31FUJ	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	1.0806143906174663	[67]	[168]	9	hSpCas9	negative selection	10126752
59466762	59466785	18	-	28162770	P31FUJ	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.46347731917093554	[186]	[302]	5	hSpCas9	negative selection	10126753
59439763	59439786	18	+	28162770	P31FUJ	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.8623550286259613	[109]	[234]	8	hSpCas9	negative selection	10126754
59466864	59466887	18	-	28162770	P31FUJ	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	-0.4146405274001916	[227]	[200]	-4	hSpCas9	negative selection	10126755
59439550	59439573	18	-	28162770	P31FUJ	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	0.7531682356815631	[154]	[306]	8	hSpCas9	negative selection	10126756
59469498	59469521	18	-	28162770	P31FUJ	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.3408576472412765	[298]	[444]	4	hSpCas9	negative selection	10126757
59466806	59466829	18	-	28162770	P31FUJ	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	1.1698302739736846	[72]	[192]	9	hSpCas9	negative selection	10126758
59439789	59439812	18	-	28162770	TF1	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10296118
59466762	59466785	18	-	28162770	TF1	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	NaN	[NaN]	[218]	1	hSpCas9	negative selection	10296119
59439763	59439786	18	+	28162770	TF1	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10296120
59466864	59466887	18	-	28162770	TF1	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	NaN	[NaN]	[273]	1	hSpCas9	negative selection	10296121
59439550	59439573	18	-	28162770	TF1	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10296122
59469498	59469521	18	-	28162770	TF1	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	NaN	[NaN]	[434]	1	hSpCas9	negative selection	10296123
59466806	59466829	18	-	28162770	TF1	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	NaN	[NaN]	[163]	1	hSpCas9	negative selection	10296124
59439789	59439812	18	-	28162770	SKM1	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	-0.915111102413487	[15]	[14]	-6	hSpCas9	negative selection	10465484
59466762	59466785	18	-	28162770	SKM1	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.2168175508685227	[54]	[112]	2	hSpCas9	negative selection	10465485
59439763	59439786	18	+	28162770	SKM1	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.04234320262042818	[38]	[70]	0	hSpCas9	negative selection	10465486
59466864	59466887	18	-	28162770	SKM1	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	0.2493829352147599	[68]	[144]	2	hSpCas9	negative selection	10465487
59439550	59439573	18	-	28162770	SKM1	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	1.4548385073368189	[12]	[62]	9	hSpCas9	negative selection	10465488
59469498	59469521	18	-	28162770	SKM1	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.16109034406755068	[73]	[116]	-1	hSpCas9	negative selection	10465489
59466806	59466829	18	-	28162770	SKM1	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	-2.2005133212757353	[25]	[9]	-8	hSpCas9	negative selection	10465490
59439789	59439812	18	-	28162770	SKM1	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	-0.915111102413487	[15]	[14]	-6	hSpCas9	negative selection	10634850
59466762	59466785	18	-	28162770	SKM1	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.2168175508685227	[54]	[112]	2	hSpCas9	negative selection	10634851
59439763	59439786	18	+	28162770	SKM1	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.04234320262042818	[38]	[70]	0	hSpCas9	negative selection	10634852
59466864	59466887	18	-	28162770	SKM1	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	0.2493829352147599	[68]	[144]	2	hSpCas9	negative selection	10634853
59439550	59439573	18	-	28162770	SKM1	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	1.4548385073368189	[12]	[62]	9	hSpCas9	negative selection	10634854
59469498	59469521	18	-	28162770	SKM1	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.16109034406755068	[73]	[116]	-1	hSpCas9	negative selection	10634855
59466806	59466829	18	-	28162770	SKM1	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	-2.2005133212757353	[25]	[9]	-8	hSpCas9	negative selection	10634856
59439789	59439812	18	-	28162770	PL21	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	0.6949043062388981	[87]	[61]	6	hSpCas9	negative selection	10804216
59466762	59466785	18	-	28162770	PL21	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.11200870421065501	[269]	[126]	1	hSpCas9	negative selection	10804217
59439763	59439786	18	+	28162770	PL21	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	1.509243669019099	[112]	[139]	9	hSpCas9	negative selection	10804218
59466864	59466887	18	-	28162770	PL21	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	0.47382126452262263	[224]	[135]	4	hSpCas9	negative selection	10804219
59439550	59439573	18	-	28162770	PL21	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	-0.17331878103812415	[113]	[43]	-1	hSpCas9	negative selection	10804220
59469498	59469521	18	-	28162770	PL21	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.5676869433816466	[251]	[73]	-4	hSpCas9	negative selection	10804221
59466806	59466829	18	-	28162770	PL21	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	-0.20425064059001485	[44]	[16]	-1	hSpCas9	negative selection	10804222
59439789	59439812	18	-	28162770	P31FUJ	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	1.0806143906174663	[67]	[168]	9	hSpCas9	negative selection	10973582
59466762	59466785	18	-	28162770	P31FUJ	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.46347731917093554	[186]	[302]	5	hSpCas9	negative selection	10973583
59439763	59439786	18	+	28162770	P31FUJ	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.8623550286259613	[109]	[234]	8	hSpCas9	negative selection	10973584
59466864	59466887	18	-	28162770	P31FUJ	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	-0.4146405274001916	[227]	[200]	-4	hSpCas9	negative selection	10973585
59439550	59439573	18	-	28162770	P31FUJ	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	0.7531682356815631	[154]	[306]	8	hSpCas9	negative selection	10973586
59469498	59469521	18	-	28162770	P31FUJ	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.3408576472412765	[298]	[444]	4	hSpCas9	negative selection	10973587
59466806	59466829	18	-	28162770	P31FUJ	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	1.1698302739736846	[72]	[192]	9	hSpCas9	negative selection	10973588
59439789	59439812	18	-	28162770	OCIAML5	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	0.7328959298571593	[44]	[134]	6	hSpCas9	negative selection	11142948
59466762	59466785	18	-	28162770	OCIAML5	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.8189849065708683	[102]	[327]	7	hSpCas9	negative selection	11142949
59439763	59439786	18	+	28162770	OCIAML5	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	-0.09764377962124438	[114]	[193]	0	hSpCas9	negative selection	11142950
59466864	59466887	18	-	28162770	OCIAML5	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	0.5837524905513498	[111]	[302]	5	hSpCas9	negative selection	11142951
59439550	59439573	18	-	28162770	OCIAML5	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	0.6033851968607552	[65]	[180]	5	hSpCas9	negative selection	11142952
59469498	59469521	18	-	28162770	OCIAML5	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.1931626831290007	[156]	[323]	1	hSpCas9	negative selection	11142953
59466806	59466829	18	-	28162770	OCIAML5	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	1.8108984418584324	[32]	[208]	9	hSpCas9	negative selection	11142954
59439789	59439812	18	-	28162770	EOL1	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	-0.49048972770830934	[103]	[38]	-4	hSpCas9	negative selection	11312314
59466762	59466785	18	-	28162770	EOL1	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.19574949827572702	[410]	[247]	1	hSpCas9	negative selection	11312315
59439763	59439786	18	+	28162770	EOL1	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.45380083970540314	[175]	[126]	4	hSpCas9	negative selection	11312316
59466864	59466887	18	-	28162770	EOL1	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	0.8398665456470964	[420]	[396]	7	hSpCas9	negative selection	11312317
59439550	59439573	18	-	28162770	EOL1	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	0.48094112009491985	[101]	[74]	4	hSpCas9	negative selection	11312318
59469498	59469521	18	-	28162770	EOL1	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.466342413135317	[293]	[213]	4	hSpCas9	negative selection	11312319
59466806	59466829	18	-	28162770	EOL1	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	1.0970149675753005	[62]	[70]	8	hSpCas9	negative selection	11312320
59439789	59439812	18	-	28162770	MOLM13	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	0.371213362132905	[107]	[100]	2	hSpCas9	negative selection	11481680
59466762	59466785	18	-	28162770	MOLM13	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.6610726781244012	[334]	[382]	5	hSpCas9	negative selection	11481681
59439763	59439786	18	+	28162770	MOLM13	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	1.355648116974901	[166]	[308]	9	hSpCas9	negative selection	11481682
59466864	59466887	18	-	28162770	MOLM13	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	2.1712380858550815	[342]	[1116]	9	hSpCas9	negative selection	11481683
59439550	59439573	18	-	28162770	MOLM13	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	-0.11707311917657748	[113]	[75]	0	hSpCas9	negative selection	11481684
59469498	59469521	18	-	28162770	MOLM13	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.13244648018273508	[428]	[339]	0	hSpCas9	negative selection	11481685
59466806	59466829	18	-	28162770	MOLM13	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	-0.054063321650776874	[55]	[38]	0	hSpCas9	negative selection	11481686
59439789	59439812	18	-	28162770	HEL	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	-0.712741822598032	[86]	[33]	-4	hSpCas9	negative selection	11651046
59466762	59466785	18	-	28162770	HEL	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.7599223713706961	[259]	[281]	6	hSpCas9	negative selection	11651047
59439763	59439786	18	+	28162770	HEL	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.979334976676555	[136]	[172]	8	hSpCas9	negative selection	11651048
59466864	59466887	18	-	28162770	HEL	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	0.9420181879425192	[320]	[394]	7	hSpCas9	negative selection	11651049
59439550	59439573	18	-	28162770	HEL	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	-0.34594585477180895	[126]	[63]	-2	hSpCas9	negative selection	11651050
59469498	59469521	18	-	28162770	HEL	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.5155036437042493	[307]	[281]	4	hSpCas9	negative selection	11651051
59466806	59466829	18	-	28162770	HEL	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	0.42772594102950645	[64]	[55]	3	hSpCas9	negative selection	11651052
59439789	59439812	18	-	28162770	MV411	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	1.5567656088905042	[68]	[170]	9	hSpCas9	negative selection	11820412
59466762	59466785	18	-	28162770	MV411	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.717277435300206	[225]	[312]	6	hSpCas9	negative selection	11820413
59439763	59439786	18	+	28162770	MV411	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	1.1959072501426933	[113]	[219]	9	hSpCas9	negative selection	11820414
59466864	59466887	18	-	28162770	MV411	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	0.39944064422782527	[224]	[249]	3	hSpCas9	negative selection	11820415
59439550	59439573	18	-	28162770	MV411	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	0.6669764422965601	[79]	[106]	6	hSpCas9	negative selection	11820416
59469498	59469521	18	-	28162770	MV411	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.34625528700069064	[267]	[286]	3	hSpCas9	negative selection	11820417
59466806	59466829	18	-	28162770	MV411	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	-0.14487987199598473	[41]	[31]	-1	hSpCas9	negative selection	11820418
59439789	59439812	18	-	28162770	MONOMAC1	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	0.4482982716410844	[38]	[60]	4	hSpCas9	negative selection	11989778
59466762	59466785	18	-	28162770	MONOMAC1	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	-0.04196745056672019	[140]	[156]	0	hSpCas9	negative selection	11989779
59439763	59439786	18	+	28162770	MONOMAC1	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.2673667295402697	[78]	[108]	2	hSpCas9	negative selection	11989780
59466864	59466887	18	-	28162770	MONOMAC1	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	-0.7501152867609238	[178]	[121]	-6	hSpCas9	negative selection	11989781
59439550	59439573	18	-	28162770	MONOMAC1	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	-0.1970368470595537	[71]	[71]	-2	hSpCas9	negative selection	11989782
59469498	59469521	18	-	28162770	MONOMAC1	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.9088543215311844	[150]	[324]	8	hSpCas9	negative selection	11989783
59466806	59466829	18	-	28162770	MONOMAC1	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	2.329031964608034	[24]	[143]	9	hSpCas9	negative selection	11989784
59439789	59439812	18	-	28162770	OCIAML2	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	0.43626077036635735	[21]	[164]	4	hSpCas9	negative selection	12159144
59466762	59466785	18	-	28162770	OCIAML2	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	-0.3511227307860722	[54]	[238]	-3	hSpCas9	negative selection	12159145
59439763	59439786	18	+	28162770	OCIAML2	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.861566605099028	[13]	[140]	8	hSpCas9	negative selection	12159146
59466864	59466887	18	-	28162770	OCIAML2	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	0.6438000636084478	[52]	[458]	6	hSpCas9	negative selection	12159147
59439550	59439573	18	-	28162770	OCIAML2	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	0.2819326239750636	[22]	[154]	2	hSpCas9	negative selection	12159148
59469498	59469521	18	-	28162770	OCIAML2	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	0.45183357428681836	[42]	[325]	4	hSpCas9	negative selection	12159149
59466806	59466829	18	-	28162770	OCIAML2	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	-0.2576361019079627	[10]	[50]	-2	hSpCas9	negative selection	12159150
59439789	59439812	18	-	28162770	OCIAML3	viability	CCAGGACCAAAGGGAAGCCCAGG	CCBE1	ENSG00000183287	-0.41343539468234236	[14]	[33]	-3	hSpCas9	negative selection	12328510
59466762	59466785	18	-	28162770	OCIAML3	viability	GATGGGAAGACATGTACCAGGGG	CCBE1	ENSG00000183287	0.21017303393829734	[64]	[226]	2	hSpCas9	negative selection	12328511
59439763	59439786	18	+	28162770	OCIAML3	viability	CAGGAGGGCCTGGCATACCGGGG	CCBE1	ENSG00000183287	0.45661843274580494	[34]	[144]	4	hSpCas9	negative selection	12328512
59466864	59466887	18	-	28162770	OCIAML3	viability	GATGAGTGTGCCAGCAGCAATGG	CCBE1	ENSG00000183287	0.7906562099111618	[53]	[281]	7	hSpCas9	negative selection	12328513
59439550	59439573	18	-	28162770	OCIAML3	viability	CCAGGGGCACCAGGAAGAGATGG	CCBE1	ENSG00000183287	-1.1579085255174897	[33]	[45]	-7	hSpCas9	negative selection	12328514
59469498	59469521	18	-	28162770	OCIAML3	viability	GATATGACCGGGAGAGACACCGG	CCBE1	ENSG00000183287	-0.6600968307819355	[66]	[127]	-5	hSpCas9	negative selection	12328515
59466806	59466829	18	-	28162770	OCIAML3	viability	GCAGCTACCGCTGCGAGTGCCGG	CCBE1	ENSG00000183287	1.455235878695686	[17]	[148]	9	hSpCas9	negative selection	12328516