Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1001
• Symbol: CDH3
• Description: cadherin 3

DataSource: http://genomecrispr.dkfz.de/#!/results/CDH3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
68691828	68691851	16	-	26472758	Jiyoye	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	5.53645839845084	[0]	[34]	9	hSpCas9	negative selection	28482
68678130	68678153	16	+	26472758	Jiyoye	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	1.5327062635897324	[98]	[215]	8	hSpCas9	negative selection	28483
68678617	68678640	16	+	26472758	Jiyoye	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	5.494638222756212	[1]	[67]	9	hSpCas9	negative selection	28484
68678859	68678882	16	+	26472758	Jiyoye	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	-0.09999495860913177	[360]	[253]	0	hSpCas9	negative selection	28485
68684761	68684784	16	-	26472758	Jiyoye	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-0.9272436575646859	[57]	[22]	-6	hSpCas9	negative selection	28486
68687524	68687547	16	-	26472758	Jiyoye	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	-0.38423799668270936	[179]	[103]	-3	hSpCas9	negative selection	28487
68687668	68687691	16	-	26472758	Jiyoye	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-4.914752713381489	[39]	[0]	-9	hSpCas9	negative selection	28488
68691828	68691851	16	-	26472758	KBM7	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	0.7369525885334225	[144,105]	[63,126]	7	hSpCas9	negative selection	219600
68678130	68678153	16	+	26472758	KBM7	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	0.30980665960586773	[818,687]	[533,350]	3	hSpCas9	negative selection	219601
68678617	68678640	16	+	26472758	KBM7	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	1.2887695357464557	[201,149]	[282,125]	9	hSpCas9	negative selection	219602
68678859	68678882	16	+	26472758	KBM7	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	0.10368091113334144	[1416,1325]	[581,793]	1	hSpCas9	negative selection	219603
68684761	68684784	16	-	26472758	KBM7	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-0.25647232927076624	[271,200]	[89,93]	-2	hSpCas9	negative selection	219604
68687524	68687547	16	-	26472758	KBM7	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	1.082562391209612	[373,236]	[341,259]	9	hSpCas9	negative selection	219605
68687668	68687691	16	-	26472758	KBM7	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-2.575106781233307	[343,216]	[7,33]	-9	hSpCas9	negative selection	219606
68691828	68691851	16	-	26472758	Raji	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	-2.5364726544011256	[49]	[1]	-9	hSpCas9	negative selection	410718
68678130	68678153	16	+	26472758	Raji	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	0.6769708102078398	[282]	[104]	6	hSpCas9	negative selection	410719
68678617	68678640	16	+	26472758	Raji	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	-0.5819156251622923	[128]	[19]	-4	hSpCas9	negative selection	410720
68678859	68678882	16	+	26472758	Raji	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	0.1687840800377427	[781]	[203]	1	hSpCas9	negative selection	410721
68684761	68684784	16	-	26472758	Raji	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-1.4091919903673067	[205]	[17]	-7	hSpCas9	negative selection	410722
68687524	68687547	16	-	26472758	Raji	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	-0.015998880131682935	[243]	[55]	0	hSpCas9	negative selection	410723
68687668	68687691	16	-	26472758	Raji	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-4.536472654401125	[99]	[0]	-9	hSpCas9	negative selection	410724
68691828	68691851	16	-	26472758	K562	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	-2.1478986951123136	[83]	[15]	-7	hSpCas9	negative selection	601836
68678130	68678153	16	+	26472758	K562	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	-0.19226376565237685	[581]	[429]	-1	hSpCas9	negative selection	601837
68678617	68678640	16	+	26472758	K562	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	0.7527056376487741	[160]	[228]	6	hSpCas9	negative selection	601838
68678859	68678882	16	+	26472758	K562	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	-0.7723795234966861	[1122]	[554]	-4	hSpCas9	negative selection	601839
68684761	68684784	16	-	26472758	K562	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-2.0710830980614823	[223]	[44]	-7	hSpCas9	negative selection	601840
68687524	68687547	16	-	26472758	K562	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	1.0343046361084356	[272]	[471]	8	hSpCas9	negative selection	601841
68687668	68687691	16	-	26472758	K562	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-6.409023510937476	[301]	[2]	-9	hSpCas9	negative selection	601842
68676435	68676458	16	+	26627737	DLD1	viability	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	0.34178882769605234	[167]	[69,123,15]	3	hSpCas9	negative selection	795101
68678575	68678598	16	+	26627737	DLD1	viability	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.8249808360880354	[213]	[59,125,162]	7	hSpCas9	negative selection	795102
68678770	68678793	16	-	26627737	DLD1	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.1549099736872226	[1046]	[430,497,195]	1	hSpCas9	negative selection	795103
68679837	68679860	16	+	26627737	DLD1	viability	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	-0.15730297137429794	[336]	[62,104,112]	-2	hSpCas9	negative selection	795104
68676435	68676458	16	+	26627737	GBM cells	viability after 5 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	0.7733829928018268	[125]	[103,126]	9	hSpCas9	negative selection	877416
68678575	68678598	16	+	26627737	GBM cells	viability after 5 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.04606756866933981	[148]	[75,88]	0	hSpCas9	negative selection	877417
68678770	68678793	16	-	26627737	GBM cells	viability after 5 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.418879120760406	[453]	[306,343]	6	hSpCas9	negative selection	877418
68679837	68679860	16	+	26627737	GBM cells	viability after 5 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	-0.1692576277558937	[259]	[125,121]	-3	hSpCas9	negative selection	877419
68676435	68676458	16	+	26627737	GBM cells	viability after 13 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	0.35797276707772163	[125]	[80,92]	4	hSpCas9	negative selection	959731
68678575	68678598	16	+	26627737	GBM cells	viability after 13 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.6438302001833816	[148]	[138,115]	7	hSpCas9	negative selection	959732
68678770	68678793	16	-	26627737	GBM cells	viability after 13 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.7628122523397424	[453]	[353,469]	8	hSpCas9	negative selection	959733
68679837	68679860	16	+	26627737	GBM cells	viability after 13 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	0.11906319105035588	[259]	[150,154]	1	hSpCas9	negative selection	959734
68676435	68676458	16	+	26627737	GBM cells	viability after 21 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	0.28704156828362115	[125]	[82,83]	3	hSpCas9	negative selection	1042046
68678575	68678598	16	+	26627737	GBM cells	viability after 21 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.9809877381504821	[148]	[164,154]	8	hSpCas9	negative selection	1042047
68678770	68678793	16	-	26627737	GBM cells	viability after 21 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.743566338767259	[453]	[448,379]	7	hSpCas9	negative selection	1042048
68679837	68679860	16	+	26627737	GBM cells	viability after 21 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	0.1796933908400672	[259]	[171,148]	2	hSpCas9	negative selection	1042049
68676435	68676458	16	+	26627737	RPE1	viability after 9 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	-0.10919417308683027	[812]	[252,213]	-1	hSpCas9	negative selection	1124361
68678575	68678598	16	+	26627737	RPE1	viability after 9 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	3.2698373027868346	[115]	[241,489]	9	hSpCas9	negative selection	1124362
68678770	68678793	16	-	26627737	RPE1	viability after 9 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.665654916978313	[2100]	[990,1110]	4	hSpCas9	negative selection	1124363
68679837	68679860	16	+	26627737	RPE1	viability after 9 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	1.7863078953713147	[309]	[215,487]	8	hSpCas9	negative selection	1124364
68676435	68676458	16	+	26627737	RPE1	viability after 12 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	-0.40918165043032	[812]	[197,128]	-3	hSpCas9	negative selection	1206676
68678575	68678598	16	+	26627737	RPE1	viability after 12 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	3.1946830554620185	[115]	[330,236]	9	hSpCas9	negative selection	1206677
68678770	68678793	16	-	26627737	RPE1	viability after 12 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.5752619673338837	[2100]	[926,749]	4	hSpCas9	negative selection	1206678
68679837	68679860	16	+	26627737	RPE1	viability after 12 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	2.339326929883272	[309]	[250,601]	9	hSpCas9	negative selection	1206679
68676435	68676458	16	+	26627737	RPE1	viability after 15 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	-0.5683330457835907	[812]	[233,78]	-4	hSpCas9	negative selection	1288991
68678575	68678598	16	+	26627737	RPE1	viability after 15 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	3.139675819814559	[115]	[249,326]	9	hSpCas9	negative selection	1288992
68678770	68678793	16	-	26627737	RPE1	viability after 15 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.6379544841097855	[2100]	[792,1051]	4	hSpCas9	negative selection	1288993
68679837	68679860	16	+	26627737	RPE1	viability after 15 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	2.543289318389381	[309]	[388,628]	9	hSpCas9	negative selection	1288994
68676435	68676458	16	+	26627737	RPE1	viability after 18 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	-0.6245217030224938	[812]	[165,116]	-4	hSpCas9	negative selection	1371306
68678575	68678598	16	+	26627737	RPE1	viability after 18 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	3.4601169017827575	[115]	[344,343]	9	hSpCas9	negative selection	1371307
68678770	68678793	16	-	26627737	RPE1	viability after 18 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.648108884485312	[2100]	[918,855]	4	hSpCas9	negative selection	1371308
68679837	68679860	16	+	26627737	RPE1	viability after 18 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	3.0919348990836335	[309]	[430,1014]	9	hSpCas9	negative selection	1371309
68676435	68676458	16	+	26627737	HeLa	viability after 8 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	1.698610973544375	[72]	[163,44,112]	9	hSpCas9	negative selection	1453621
68678575	68678598	16	+	26627737	HeLa	viability after 8 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.7434297298586683	[190]	[113,115,178]	6	hSpCas9	negative selection	1453622
68678770	68678793	16	-	26627737	HeLa	viability after 8 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.43699110073099656	[720]	[474,470,344]	4	hSpCas9	negative selection	1453623
68679837	68679860	16	+	26627737	HeLa	viability after 8 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	0.3569309563010391	[267]	[169,79,198]	3	hSpCas9	negative selection	1453624
68676435	68676458	16	+	26627737	HeLa	viability after 12 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	0.8763844355316648	[72]	[14,73,73]	6	hSpCas9	negative selection	1535936
68678575	68678598	16	+	26627737	HeLa	viability after 12 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	1.109864633849369	[190]	[231,187,90]	7	hSpCas9	negative selection	1535937
68678770	68678793	16	-	26627737	HeLa	viability after 12 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.7798915831085231	[720]	[632,495,410]	6	hSpCas9	negative selection	1535938
68679837	68679860	16	+	26627737	HeLa	viability after 12 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	0.604493872603229	[267]	[222,137,148]	5	hSpCas9	negative selection	1535939
68676435	68676458	16	+	26627737	HeLa	viability after 15 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	1.6716510593860785	[72]	[67,89,128]	9	hSpCas9	negative selection	1618251
68678575	68678598	16	+	26627737	HeLa	viability after 15 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	1.3715337851304878	[190]	[127,341,128]	8	hSpCas9	negative selection	1618252
68678770	68678793	16	-	26627737	HeLa	viability after 15 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.4949710856556657	[720]	[429,514,285]	4	hSpCas9	negative selection	1618253
68679837	68679860	16	+	26627737	HeLa	viability after 15 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	0.028919962937069776	[267]	[116,115,99]	0	hSpCas9	negative selection	1618254
68676435	68676458	16	+	26627737	HeLa	viability after 18 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	1.6492005762359585	[72]	[43,72,128]	9	hSpCas9	negative selection	1700566
68678575	68678598	16	+	26627737	HeLa	viability after 18 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	1.3809710118160785	[190]	[86,284,128]	8	hSpCas9	negative selection	1700567
68678770	68678793	16	-	26627737	HeLa	viability after 18 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.5288826565314702	[720]	[299,435,285]	4	hSpCas9	negative selection	1700568
68679837	68679860	16	+	26627737	HeLa	viability after 18 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	0.013216594330530906	[267]	[76,94,99]	0	hSpCas9	negative selection	1700569
68676435	68676458	16	+	26627737	HCT116	viability after 6 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	1.7320539938353112	[418]	[96,285]	8	hSpCas9	negative selection	1782881
68678575	68678598	16	+	26627737	HCT116	viability after 6 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.33439116138022734	[474]	[253,5]	1	hSpCas9	negative selection	1782882
68678770	68678793	16	-	26627737	HCT116	viability after 6 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	2.0471417815351245	[798]	[444,559]	8	hSpCas9	negative selection	1782883
68679837	68679860	16	+	26627737	HCT116	viability after 6 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	0.5455159772416915	[354]	[16,116]	3	hSpCas9	negative selection	1782884
68676435	68676458	16	+	26627737	HCT116	viability after 8 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	-0.5674127468762618	[172]	[61,70,59]	-6	hSpCas9	negative selection	1865196
68678575	68678598	16	+	26627737	HCT116	viability after 8 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.6916419038074362	[219]	[235,147,203]	6	hSpCas9	negative selection	1865197
68678770	68678793	16	-	26627737	HCT116	viability after 8 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.4493744609949014	[449]	[310,427,276]	5	hSpCas9	negative selection	1865198
68679837	68679860	16	+	26627737	HCT116	viability after 8 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	-0.027251005092731338	[294]	[208,158,111]	0	hSpCas9	negative selection	1865199
68676435	68676458	16	+	26627737	HCT116	viability after 9 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	0.7889955063447047	[418]	[299,108]	5	hSpCas9	negative selection	1947511
68678575	68678598	16	+	26627737	HCT116	viability after 9 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.5033974877806093	[474]	[114,230]	3	hSpCas9	negative selection	1947512
68678770	68678793	16	-	26627737	HCT116	viability after 9 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	1.3108234833024726	[798]	[683,406]	8	hSpCas9	negative selection	1947513
68679837	68679860	16	+	26627737	HCT116	viability after 9 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	1.2726886446963646	[354]	[223,232]	8	hSpCas9	negative selection	1947514
68676435	68676458	16	+	26627737	HCT116	viability after 12 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	0.4719452299982476	[172]	[149,117,107]	4	hSpCas9	negative selection	2029826
68678575	68678598	16	+	26627737	HCT116	viability after 12 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.15124847035583194	[219]	[116,161,107]	1	hSpCas9	negative selection	2029827
68678770	68678793	16	-	26627737	HCT116	viability after 12 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.42101824265042576	[449]	[202,404,353]	4	hSpCas9	negative selection	2029828
68679837	68679860	16	+	26627737	HCT116	viability after 12 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	-0.8058765424621909	[294]	[86,80,97]	-7	hSpCas9	negative selection	2029829
68676435	68676458	16	+	26627737	HCT116	viability after 15 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	0.24965768442130187	[172]	[127,61,164]	2	hSpCas9	negative selection	2112141
68678575	68678598	16	+	26627737	HCT116	viability after 15 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.13110656204895382	[219]	[155,102,157]	1	hSpCas9	negative selection	2112142
68678770	68678793	16	-	26627737	HCT116	viability after 15 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.41543326063837427	[449]	[349,367,316]	4	hSpCas9	negative selection	2112143
68679837	68679860	16	+	26627737	HCT116	viability after 15 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	-0.40472217753773937	[294]	[219,36,137]	-4	hSpCas9	negative selection	2112144
68676435	68676458	16	+	26627737	HCT116	viability after 18 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	-0.49429133308422646	[172]	[96,44,35]	-4	hSpCas9	negative selection	2194456
68678575	68678598	16	+	26627737	HCT116	viability after 18 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.4210173000351357	[219]	[152,96,181]	3	hSpCas9	negative selection	2194457
68678770	68678793	16	-	26627737	HCT116	viability after 18 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.5801904280395588	[449]	[211,343,422]	5	hSpCas9	negative selection	2194458
68679837	68679860	16	+	26627737	HCT116	viability after 18 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	-0.503322638609905	[294]	[33,177,83]	-4	hSpCas9	negative selection	2194459
68703901	68703924	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGTGCCACTGCACTCCAGCCTAG	CDH3	ENSG00000062038	0.4846974014178431	[92,26]	[27,6]	2	dCas9-VP64	positive selection	2390937
68689391	68689414	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGTGCTACCACGCCTGG	CDH3	ENSG00000062038	3.748247150670283	[1,20]	[67,2]	9	dCas9-VP64	positive selection	2410134
68655798	68655821	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTTGCAGTGAGCTGAGATTAAG	CDH3	ENSG00000062038	0.09247990967442199	[398,266]	[75,78]	0	dCas9-VP64	positive selection	2414611
68672161	68672184	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGTCTCGCTGTCGCCCAGGCTGG	CDH3	ENSG00000062038	0.8346262078071658	[10,1]	[2,1]	3	dCas9-VP64	positive selection	2416335
68644100	68644123	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAACAACGAATCCCAGGTCTGG	CDH3	ENSG00000062038	3.1665519797745505	[81,18]	[163,30]	8	dCas9-VP64	positive selection	2428635
68644112	68644135	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAGATAAACGCCAGACCTGGG	CDH3	ENSG00000062038	1.4369663353938926	[8,13]	[10,1]	5	dCas9-VP64	positive selection	2428636
68644060	68644083	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCACTTCGTGTCTAACGTAGTGG	CDH3	ENSG00000062038	1.4157519218787478	[44,27]	[3,39]	5	dCas9-VP64	positive selection	2428637
68650576	68650599	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGTGAGCCACCACGCCCGG	CDH3	ENSG00000062038	1.2080578617800355	[188,10]	[73,23]	5	dCas9-VP64	positive selection	2430242
68704136	68704159	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATTAGCCGGGCGTGGTGGCGGG	CDH3	ENSG00000062038	0.43464799396045883	[0,13]	[2,0]	2	dCas9-VP64	positive selection	2460873
68640551	68640574	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGGAGAATCGCTTGAACCTAG	CDH3	ENSG00000062038	-0.7872021050505377	[82,16]	[7,2]	-4	dCas9-VP64	positive selection	2464211
68690800	68690823	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAGGCTGAGGCAGGAGAATAG	CDH3	ENSG00000062038	1.7244712313844854	[32,17]	[27,7]	6	dCas9-VP64	positive selection	2468525
68703901	68703924	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGTGCCACTGCACTCCAGCCTAG	CDH3	ENSG00000062038	0.6971910689480432	[49,47]	[24,25]	5	dCas9-VP64	positive selection	2486192
68689391	68689414	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGTGCTACCACGCCTGG	CDH3	ENSG00000062038	-0.05566307319411967	[8,287]	[6,81]	0	dCas9-VP64	positive selection	2505389
68655798	68655821	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTTGCAGTGAGCTGAGATTAAG	CDH3	ENSG00000062038	-0.8679421240235777	[178,269]	[31,46]	-7	dCas9-VP64	positive selection	2509866
68672161	68672184	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGTCTCGCTGTCGCCCAGGCTGG	CDH3	ENSG00000062038	-1.711674582430177	[43,184]	[8,12]	-9	dCas9-VP64	positive selection	2511590
68644100	68644123	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAACAACGAATCCCAGGTCTGG	CDH3	ENSG00000062038	-0.6919138331555958	[248,106]	[34,35]	-6	dCas9-VP64	positive selection	2523890
68644112	68644135	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAGATAAACGCCAGACCTGGG	CDH3	ENSG00000062038	-0.13765556257204892	[53,363]	[35,83]	-1	dCas9-VP64	positive selection	2523891
68644060	68644083	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCACTTCGTGTCTAACGTAGTGG	CDH3	ENSG00000062038	-0.4599727590589594	[125,26]	[28,7]	-5	dCas9-VP64	positive selection	2523892
68650576	68650599	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGTGAGCCACCACGCCCGG	CDH3	ENSG00000062038	1.0270683763310697	[166,152]	[69,140]	6	dCas9-VP64	positive selection	2525497
68704136	68704159	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATTAGCCGGGCGTGGTGGCGGG	CDH3	ENSG00000062038	-0.5732050346504929	[30,53]	[10,6]	-5	dCas9-VP64	positive selection	2556128
68640551	68640574	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGGAGAATCGCTTGAACCTAG	CDH3	ENSG00000062038	-0.42856361530074616	[34,35]	[8,6]	-4	dCas9-VP64	positive selection	2559466
68690800	68690823	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAGGCTGAGGCAGGAGAATAG	CDH3	ENSG00000062038	-0.1093774260535414	[64,117]	[17,35]	-1	dCas9-VP64	positive selection	2563780
68678197	68678220	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGACACAAGAGAGATTGGGTGG	CDH3	ENSG00000062038	0.37263738143316866	[5,5]	[5,6]	7	hSpCas9	positive selection	2978085
68684619	68684642	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACGTTGAAGTGACCAACGAGG	CDH3	ENSG00000062038	0.09920001018741922	[3,2]	[4,1]	2	hSpCas9	positive selection	2978086
68678231	68678254	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGTCCCTGAAAATGGCAAGGG	CDH3	ENSG00000062038	0.37143018202082334	[3,3]	[3,4]	7	hSpCas9	positive selection	2978087
68679807	68679830	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTGATGCAGGTGACAGCCACGG	CDH3	ENSG00000062038	-0.1494675290589278	[4,4]	[3,2]	-2	hSpCas9	positive selection	2978088
68678197	68678220	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGACACAAGAGAGATTGGGTGG	CDH3	ENSG00000062038	0.29182540123485606	[5,5]	[5,4]	5	hSpCas9	positive selection	3045943
68684619	68684642	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACGTTGAAGTGACCAACGAGG	CDH3	ENSG00000062038	-0.20084497236216972	[3,3]	[2,0]	-3	hSpCas9	positive selection	3045944
68678231	68678254	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGTCCCTGAAAATGGCAAGGG	CDH3	ENSG00000062038	-0.2618525065834596	[3,3]	[2,0]	-4	hSpCas9	positive selection	3045945
68679807	68679830	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTGATGCAGGTGACAGCCACGG	CDH3	ENSG00000062038	0.3438763521007727	[4,4]	[3,3]	6	hSpCas9	positive selection	3045946
68678646	68678669		-	24336571	A375	resistance to PLX after 7 days	AAGGCTACTTGCCTCATACTTGG	CDH3	ENSG00000062038	-0.02675867432547996	[19,15]	[15,18]	0	hSpCas9	positive selection	3104505
68678262	68678285		-	24336571	A375	resistance to PLX after 7 days	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.15269147803018712	[56,47]	[55,59]	5	hSpCas9	positive selection	3104506
68678180	68678203		-	24336571	A375	resistance to PLX after 7 days	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.10395733219401737	[9,8]	[8,8]	-3	hSpCas9	positive selection	3104507
68678570	68678593		-	24336571	A375	resistance to PLX after 7 days	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.16875785169627974	[12,11]	[10,11]	-5	hSpCas9	positive selection	3104508
68678646	68678669		-	24336571	A375	resistance to PLX after 14 days	AAGGCTACTTGCCTCATACTTGG	CDH3	ENSG00000062038	0.16065094444104855	[28,13]	[9,11]	1	hSpCas9	positive selection	3162298
68678262	68678285		-	24336571	A375	resistance to PLX after 14 days	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.18864788522567943	[68,48]	[34,26]	2	hSpCas9	positive selection	3162299
68678180	68678203		-	24336571	A375	resistance to PLX after 14 days	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	0.2622002619196558	[8,5]	[2,4]	2	hSpCas9	positive selection	3162300
68678570	68678593		-	24336571	A375	resistance to PLX after 14 days	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.5727724158484054	[17,10]	[4,3]	-6	hSpCas9	positive selection	3162301
68678646	68678669		-	24336571	A375	viability after 7 days	AAGGCTACTTGCCTCATACTTGG	CDH3	ENSG00000062038	0.4415443859618977	[13]	[19,15]	6	hSpCas9	negative selection	3220091
68678262	68678285		-	24336571	A375	viability after 7 days	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.6578473906976952	[34]	[56,47]	8	hSpCas9	negative selection	3220092
68678180	68678203		-	24336571	A375	viability after 7 days	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.2657559174358253	[11]	[9,8]	-4	hSpCas9	negative selection	3220093
68678570	68678593		-	24336571	A375	viability after 7 days	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.08448289720499205	[12]	[12,11]	1	hSpCas9	negative selection	3220094
68678646	68678669		-	24336571	A375	viability after 14 days	AAGGCTACTTGCCTCATACTTGG	CDH3	ENSG00000062038	0.694071834183574	[13]	[28,13]	8	hSpCas9	negative selection	3277884
68678262	68678285		-	24336571	A375	viability after 14 days	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.8346616082432772	[34]	[68,48]	9	hSpCas9	negative selection	3277885
68678180	68678203		-	24336571	A375	viability after 14 days	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.6123094853112423	[11]	[8,5]	-6	hSpCas9	negative selection	3277886
68678570	68678593		-	24336571	A375	viability after 14 days	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.2999815346347722	[12]	[17,10]	4	hSpCas9	negative selection	3277887
68678820	68678843	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	2.558788629539687	[376,375]	[0,27]	8	hSpCas9	positive selection	3342325
68678180	68678203	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.915052270130814	[286,289]	[0,0]	-6	hSpCas9	positive selection	3342326
68678262	68678285	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	1.0763120313417165	[80,63]	[0,0]	5	hSpCas9	positive selection	3342327
68678570	68678593	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-1.05555674383852	[317,317]	[0,0]	-7	hSpCas9	positive selection	3361558
68678770	68678793	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	-0.28956824844180157	[186,186]	[0,0]	-2	hSpCas9	positive selection	3361559
68678608	68678631	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	0.8310614567437372	[85,85]	[0,0]	4	hSpCas9	positive selection	3361560
68678196	68678219	16	+	26780180	HT29	viability (Avana library 4 designs)	AAGACACAAGAGAGATTGGGTGG	CDH3	ENSG00000062038	0.843301142031653	[]	[]	3	hSpCas9	negative selection	3414396
68684618	68684641	16	+	26780180	HT29	viability (Avana library 4 designs)	GTACGTTGAAGTGACCAACGAGG	CDH3	ENSG00000062038	0.443459622423015	[]	[]	1	hSpCas9	negative selection	3414397
68678230	68678253	16	+	26780180	HT29	viability (Avana library 4 designs)	TCTGTCCCTGAAAATGGCAAGGG	CDH3	ENSG00000062038	1.25484998726119	[]	[]	5	hSpCas9	negative selection	3414398
68679806	68679829	16	+	26780180	HT29	viability (Avana library 4 designs)	TGTGATGCAGGTGACAGCCACGG	CDH3	ENSG00000062038	1.17599606666677	[]	[]	4	hSpCas9	negative selection	3414399
68678230	68678253	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGTCCCTGAAAATGGCAAGGG	CDH3	ENSG00000062038	2.8480643033331	[]	[]	4	hSpCas9	negative selection	3490891
68684618	68684641	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTACGTTGAAGTGACCAACGAGG	CDH3	ENSG00000062038	3.75177738242507	[]	[]	6	hSpCas9	negative selection	3490892
68678196	68678219	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGACACAAGAGAGATTGGGTGG	CDH3	ENSG00000062038	1.60348801065308	[]	[]	2	hSpCas9	negative selection	3490893
68679806	68679829	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGATGCAGGTGACAGCCACGG	CDH3	ENSG00000062038	4.43513052801459	[]	[]	7	hSpCas9	negative selection	3490894
68682446	68682469	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCCACCCTGAGAGCAACCAGGG	CDH3	ENSG00000062038	1.18121664625806	[]	[]	1	hSpCas9	negative selection	3490895
68679823	68679846	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGGCATCATCCTCATCCGTGG	CDH3	ENSG00000062038	9.47868268319256	[]	[]	9	hSpCas9	negative selection	3490896
68678230	68678253	16	+	26780180	A375	viability (Avana lentiGuide)	TCTGTCCCTGAAAATGGCAAGGG	CDH3	ENSG00000062038	1.00748958446019	[]	[]	1	hSpCas9	negative selection	3599550
68684618	68684641	16	+	26780180	A375	viability (Avana lentiGuide)	GTACGTTGAAGTGACCAACGAGG	CDH3	ENSG00000062038	3.4663399832229	[]	[]	3	hSpCas9	negative selection	3599551
68678196	68678219	16	+	26780180	A375	viability (Avana lentiGuide)	AAGACACAAGAGAGATTGGGTGG	CDH3	ENSG00000062038	1.34629021236299	[]	[]	1	hSpCas9	negative selection	3599552
68679806	68679829	16	+	26780180	A375	viability (Avana lentiGuide)	TGTGATGCAGGTGACAGCCACGG	CDH3	ENSG00000062038	-3.13412265466931	[]	[]	-5	hSpCas9	negative selection	3599553
68682446	68682469	16	+	26780180	A375	viability (Avana lentiGuide)	ACCCACCCTGAGAGCAACCAGGG	CDH3	ENSG00000062038	-2.85888721959764	[]	[]	-5	hSpCas9	negative selection	3599554
68679823	68679846	16	-	26780180	A375	viability (Avana lentiGuide)	GATGGCATCATCCTCATCCGTGG	CDH3	ENSG00000062038	1.33368903890647	[]	[]	1	hSpCas9	negative selection	3599555
68678230	68678253	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGTCCCTGAAAATGGCAAGGG	CDH3	ENSG00000062038	-0.07564359425780323	[5]	[5,4]	-1	hSpCas9	positive selection	3708209
68684618	68684641	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACGTTGAAGTGACCAACGAGG	CDH3	ENSG00000062038	0.21081505574057488	[4]	[5,5]	6	hSpCas9	positive selection	3708210
68678196	68678219	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGACACAAGAGAGATTGGGTGG	CDH3	ENSG00000062038	0.04075322114930868	[6]	[6,5]	1	hSpCas9	positive selection	3708211
68679806	68679829	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGATGCAGGTGACAGCCACGG	CDH3	ENSG00000062038	0.28070777085746035	[5]	[7,6]	7	hSpCas9	positive selection	3708212
68682446	68682469	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCCACCCTGAGAGCAACCAGGG	CDH3	ENSG00000062038	0.1330510954789615	[5]	[6,5]	3	hSpCas9	positive selection	3708213
68679823	68679846	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGGCATCATCCTCATCCGTGG	CDH3	ENSG00000062038	0.6597308044702976	[3]	[6,6]	9	hSpCas9	positive selection	3708214
68678230	68678253	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGTCCCTGAAAATGGCAAGGG	CDH3	ENSG00000062038	0.29545254462516013	[5]	[5,5]	8	hSpCas9	positive selection	3816816
68684618	68684641	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACGTTGAAGTGACCAACGAGG	CDH3	ENSG00000062038	0.16747730254857837	[5]	[5,4]	4	hSpCas9	positive selection	3816817
68678196	68678219	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGACACAAGAGAGATTGGGTGG	CDH3	ENSG00000062038	0.1679488827975631	[7]	[6,6]	4	hSpCas9	positive selection	3816818
68679806	68679829	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGATGCAGGTGACAGCCACGG	CDH3	ENSG00000062038	0.34803045374749597	[6]	[6,6]	8	hSpCas9	positive selection	3816819
68682446	68682469	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCCACCCTGAGAGCAACCAGGG	CDH3	ENSG00000062038	0.2362263183102617	[6]	[6,6]	6	hSpCas9	positive selection	3816820
68679823	68679846	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGGCATCATCCTCATCCGTGG	CDH3	ENSG00000062038	-0.7727059724251084	[4]	[1,2]	-7	hSpCas9	positive selection	3816821
68678820	68678843	16	-	26780180	A375	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	0.366454571731195	[]	[]	0	hSpCas9	negative selection	3924986
68678770	68678793	16	-	26780180	A375	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	1.06572546241475	[]	[]	5	hSpCas9	negative selection	3924987
68678262	68678285	16	-	26780180	A375	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	1.16125862445172	[]	[]	6	hSpCas9	negative selection	3924988
68678180	68678203	16	-	26780180	A375	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	1.38280995913606	[]	[]	7	hSpCas9	negative selection	3924989
68678608	68678631	16	+	26780180	A375	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	1.22445622229393	[]	[]	6	hSpCas9	negative selection	3924990
68678570	68678593	16	-	26780180	A375	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	1.5365379134257	[]	[]	8	hSpCas9	negative selection	3924991
68678820	68678843	16	-	26780180	HT29	viability (GeCKOv2 library)	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.0863384367791108	[]	[]	-3	hSpCas9	negative selection	4032952
68678770	68678793	16	-	26780180	HT29	viability (GeCKOv2 library)	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	1.70484694118127	[]	[]	8	hSpCas9	negative selection	4032953
68678262	68678285	16	-	26780180	HT29	viability (GeCKOv2 library)	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	2.13548171605664	[]	[]	9	hSpCas9	negative selection	4032954
68678180	68678203	16	-	26780180	HT29	viability (GeCKOv2 library)	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	0.381370207983403	[]	[]	1	hSpCas9	negative selection	4032955
68678608	68678631	16	+	26780180	HT29	viability (GeCKOv2 library)	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	0.716228861083377	[]	[]	2	hSpCas9	negative selection	4032956
68678570	68678593	16	-	26780180	HT29	viability (GeCKOv2 library)	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	1.97736719249733	[]	[]	9	hSpCas9	negative selection	4032957
68678646	68678669	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGGCTACTTGCCTCATACTTGG	CDH3	ENSG00000062038	0.3007199008406612	[3]	[3,3]	7	hSpCas9	positive selection	4126528
68678262	68678285	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.2021178360179815	[5]	[4,4]	5	hSpCas9	positive selection	4126529
68678180	68678203	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.24024177247113276	[3]	[1,1]	-5	hSpCas9	positive selection	4126530
68678570	68678593	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.0460887070752784	[3]	[1,1]	1	hSpCas9	positive selection	4126531
68678646	68678669	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGGCTACTTGCCTCATACTTGG	CDH3	ENSG00000062038	0.6654949269525169	[4]	[4,3,4,1]	4	hSpCas9	positive selection	4190550
68678262	68678285	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.5337552047856402	[4]	[5,4,4,0]	3	hSpCas9	positive selection	4190551
68678180	68678203	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	0.16261030574135013	[3]	[0,3,2,0]	1	hSpCas9	positive selection	4190552
68678570	68678593	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.7665328260559435	[4]	[0,2,2,3]	5	hSpCas9	positive selection	4190553
68678820	68678843	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	0.4258909113154271	[4]	[4,5]	8	hSpCas9	positive selection	4262374
68678180	68678203	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.09665229847816398	[4]	[3,2]	-2	hSpCas9	positive selection	4262375
68678262	68678285	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	-0.8869645609972567	[2]	[0,0]	-9	hSpCas9	positive selection	4262376
68678570	68678593	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.011238429289781582	[3]	[3,2]	0	hSpCas9	positive selection	4326652
68678770	68678793	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.19653824933671352	[2]	[3,1]	4	hSpCas9	positive selection	4326653
68678608	68678631	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.14977870084547473	[2]	[1,0]	-3	hSpCas9	positive selection	4326654
68678537	68678559	16	+	27760321	OCIAML3	viability	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.2574808130156949	[1300,942]	[907,1208]	3	hSpCas9	negative selection	4387916
68678871	68678893	16	-	27760321	OCIAML3	viability	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	-0.3404406838273606	[350,270]	[168,218]	-4	hSpCas9	negative selection	4387917
68682383	68682405	16	-	27760321	OCIAML3	viability	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	-0.10614619029199518	[400,359]	[184,394]	-1	hSpCas9	negative selection	4387918
68682406	68682428	16	+	27760321	OCIAML3	viability	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	-1.1027006755031814	[402,314]	[118,143]	-7	hSpCas9	negative selection	4387919
68684615	68684637	16	-	27760321	OCIAML3	viability	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	0.7096466468588837	[351,292]	[385,442]	8	hSpCas9	negative selection	4387920
68678537	68678559	16	+	27760321	OCIAML2	viability	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.6268424004448077	[1300,942]	[1307,1492]	8	hSpCas9	negative selection	4471379
68678871	68678893	16	-	27760321	OCIAML2	viability	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	0.30127487945144943	[350,270]	[321,288]	4	hSpCas9	negative selection	4471380
68682383	68682405	16	-	27760321	OCIAML2	viability	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	0.41773472649864885	[400,359]	[389,437]	5	hSpCas9	negative selection	4471381
68682406	68682428	16	+	27760321	OCIAML2	viability	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	-0.2560108922613154	[402,314]	[244,236]	-3	hSpCas9	negative selection	4471382
68684615	68684637	16	-	27760321	OCIAML2	viability	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	-0.11327994853450235	[351,292]	[256,217]	-1	hSpCas9	negative selection	4471383
68678537	68678559	16	+	27760321	MV411	viability	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.8128672899136644	[1300,942]	[1424,1081]	6	hSpCas9	negative selection	4554842
68678871	68678893	16	-	27760321	MV411	viability	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	-0.7243350407963063	[350,270]	[22,273]	-5	hSpCas9	negative selection	4554843
68682383	68682405	16	-	27760321	MV411	viability	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	-0.024729553332855758	[400,359]	[178,347]	0	hSpCas9	negative selection	4554844
68682406	68682428	16	+	27760321	MV411	viability	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	0.10570095939655455	[402,314]	[235,278]	0	hSpCas9	negative selection	4554845
68684615	68684637	16	-	27760321	MV411	viability	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	-1.6154849522553325	[351,292]	[21,139]	-8	hSpCas9	negative selection	4554846
68678537	68678559	16	+	27760321	HL60	viability	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.3136532768599922	[1300,942]	[1241,1006]	4	hSpCas9	negative selection	4638305
68678871	68678893	16	-	27760321	HL60	viability	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	-0.1296893779646896	[350,270]	[197,264]	-1	hSpCas9	negative selection	4638306
68682383	68682405	16	-	27760321	HL60	viability	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	0.10096886176184879	[400,359]	[298,368]	1	hSpCas9	negative selection	4638307
68682406	68682428	16	+	27760321	HL60	viability	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	-1.0537513794102555	[402,314]	[133,146]	-7	hSpCas9	negative selection	4638308
68684615	68684637	16	-	27760321	HL60	viability	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	-0.20282568769568649	[351,292]	[241,212]	-2	hSpCas9	negative selection	4638309
68678537	68678559	16	+	27760321	HT1080	viability	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.769095941686941	[942,735]	[652,478]	4	hSpCas9	negative selection	4721768
68678871	68678893	16	-	27760321	HT1080	viability	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	1.7200364952975322	[270,211]	[495,120]	8	hSpCas9	negative selection	4721769
68682383	68682405	16	-	27760321	HT1080	viability	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	1.0724323405833691	[359,280]	[236,302]	6	hSpCas9	negative selection	4721770
68682406	68682428	16	+	27760321	HT1080	viability	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	0.06209534029468855	[314,245]	[98,135]	0	hSpCas9	negative selection	4721771
68684615	68684637	16	-	27760321	HT1080	viability	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	-0.5077765636086513	[292,228]	[96,46]	-2	hSpCas9	negative selection	4721772
68678537	68678559	16	+	27760321	HT29	viability after 7 days	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.5037484941816683	[942,735]	[1563,1727,1308]	7	hSpCas9	negative selection	4805231
68678871	68678893	16	-	27760321	HT29	viability after 7 days	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	0.6357375933897601	[270,211]	[394,291,738]	8	hSpCas9	negative selection	4805232
68682383	68682405	16	-	27760321	HT29	viability after 7 days	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	0.20595559655747478	[359,280]	[634,591,228]	3	hSpCas9	negative selection	4805233
68682406	68682428	16	+	27760321	HT29	viability after 7 days	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	-0.433558194314747	[314,245]	[387,226,204]	-6	hSpCas9	negative selection	4805234
68684615	68684637	16	-	27760321	HT29	viability after 7 days	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	-0.07808148358701389	[292,228]	[279,416,252]	-1	hSpCas9	negative selection	4805235
68678537	68678559	16	+	27760321	HT29	viability after 25 days	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.9411773814275948	[942,735]	[1418,2127,2021]	9	hSpCas9	negative selection	4888694
68678871	68678893	16	-	27760321	HT29	viability after 25 days	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	0.22355528854828288	[270,211]	[299,317,352]	2	hSpCas9	negative selection	4888695
68682383	68682405	16	-	27760321	HT29	viability after 25 days	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	0.5227598263769218	[359,280]	[531,566,472]	6	hSpCas9	negative selection	4888696
68682406	68682428	16	+	27760321	HT29	viability after 25 days	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	-0.30905548786935705	[314,245]	[183,273,329]	-3	hSpCas9	negative selection	4888697
68684615	68684637	16	-	27760321	HT29	viability after 25 days	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	0.2787094696848518	[292,228]	[235,408,457]	3	hSpCas9	negative selection	4888698
68678537	68678559	16	+	27760321	HT29	viability after 22 days	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.5953731868608196	[942,735]	[1202,1627,1575]	6	hSpCas9	negative selection	4972157
68678871	68678893	16	-	27760321	HT29	viability after 22 days	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	0.441881639982656	[270,211]	[358,338,440]	5	hSpCas9	negative selection	4972158
68682383	68682405	16	-	27760321	HT29	viability after 22 days	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	0.1320278201844701	[359,280]	[358,383,476]	1	hSpCas9	negative selection	4972159
68682406	68682428	16	+	27760321	HT29	viability after 22 days	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	-0.5499811072534153	[314,245]	[120,344,200]	-5	hSpCas9	negative selection	4972160
68684615	68684637	16	-	27760321	HT29	viability after 22 days	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	0.3611499858940862	[292,228]	[211,410,545]	4	hSpCas9	negative selection	4972161
68678537	68678559	16	+	27760321	HT29	viability after 19 days	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.7849745969450896	[942,735]	[1519,1616,1804]	7	hSpCas9	negative selection	5055620
68678871	68678893	16	-	27760321	HT29	viability after 19 days	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	1.0136751680989957	[270,211]	[246,478,900]	9	hSpCas9	negative selection	5055621
68682383	68682405	16	-	27760321	HT29	viability after 19 days	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	0.5501991978828005	[359,280]	[554,472,581]	5	hSpCas9	negative selection	5055622
68682406	68682428	16	+	27760321	HT29	viability after 19 days	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	-0.27068695443975804	[314,245]	[183,498,111]	-3	hSpCas9	negative selection	5055623
68684615	68684637	16	-	27760321	HT29	viability after 19 days	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	-0.1141145096686314	[292,228]	[242,469,116]	-1	hSpCas9	negative selection	5055624
68678537	68678559	16	+	27760321	HT29	viability after 16 days	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.760580747903969	[942,735]	[1642,1488,1648]	8	hSpCas9	negative selection	5139083
68678871	68678893	16	-	27760321	HT29	viability after 16 days	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	0.028320141333396	[270,211]	[210,145,466]	0	hSpCas9	negative selection	5139084
68682383	68682405	16	-	27760321	HT29	viability after 16 days	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	0.06184846140933849	[359,280]	[300,560,248]	0	hSpCas9	negative selection	5139085
68682406	68682428	16	+	27760321	HT29	viability after 16 days	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	0.10961782418259905	[314,245]	[308,337,365]	1	hSpCas9	negative selection	5139086
68684615	68684637	16	-	27760321	HT29	viability after 16 days	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	-0.46265819945888026	[292,228]	[189,197,245]	-5	hSpCas9	negative selection	5139087
68678537	68678559	16	+	27760321	HT29	viability after 13 days	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.5162901435755225	[942,735]	[1485,1377,1318]	6	hSpCas9	negative selection	5222546
68678871	68678893	16	-	27760321	HT29	viability after 13 days	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	0.43451824421249013	[270,211]	[315,387,428]	5	hSpCas9	negative selection	5222547
68682383	68682405	16	-	27760321	HT29	viability after 13 days	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	-0.27758931896028116	[359,280]	[283,342,293]	-3	hSpCas9	negative selection	5222548
68682406	68682428	16	+	27760321	HT29	viability after 13 days	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	0.20446280128216066	[314,245]	[255,440,424]	2	hSpCas9	negative selection	5222549
68684615	68684637	16	-	27760321	HT29	viability after 13 days	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	-0.046782938626974635	[292,228]	[334,245,297]	0	hSpCas9	negative selection	5222550
68678537	68678559	16	+	27760321	HT29	viability after 10 days	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.7177871797818929	[942,735]	[1398,2022,1756]	8	hSpCas9	negative selection	5306009
68678871	68678893	16	-	27760321	HT29	viability after 10 days	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	0.18425394756515806	[270,211]	[354,278,390]	2	hSpCas9	negative selection	5306010
68682383	68682405	16	-	27760321	HT29	viability after 10 days	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	0.33624475917425645	[359,280]	[445,681,394]	4	hSpCas9	negative selection	5306011
68682406	68682428	16	+	27760321	HT29	viability after 10 days	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	-0.40800606250801025	[314,245]	[347,349,99]	-5	hSpCas9	negative selection	5306012
68684615	68684637	16	-	27760321	HT29	viability after 10 days	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	0.21597234504976098	[292,228]	[416,470,252]	3	hSpCas9	negative selection	5306013
68678537	68678559	16	+	27760321	MOLM13	viability	TACAGCATCACGGGGCCGGGGG	CDH3	ENSG00000062038	0.32845983818578195	[1300,942]	[738,827]	2	hSpCas9	negative selection	5389472
68678871	68678893	16	-	27760321	MOLM13	viability	TCTAAGACACTCCCTCGGAAGG	CDH3	ENSG00000062038	0.7184947123120053	[350,270]	[284,287]	5	hSpCas9	negative selection	5389473
68682383	68682405	16	-	27760321	MOLM13	viability	GGTAGGTGGCACGCCACGCTGG	CDH3	ENSG00000062038	1.0020191430414356	[400,359]	[819,96]	7	hSpCas9	negative selection	5389474
68682406	68682428	16	+	27760321	MOLM13	viability	TATCATGGGCGGTGACGACGGG	CDH3	ENSG00000062038	-0.8113965893395008	[402,314]	[132,98]	-5	hSpCas9	negative selection	5389475
68684615	68684637	16	-	27760321	MOLM13	viability	GTTGGTCACTTCAACGTACAGG	CDH3	ENSG00000062038	-1.554470392076807	[351,292]	[112,17]	-7	hSpCas9	negative selection	5389476
68678820	68678843	16	-	27260156	BXPC3	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.16284665171052426	[1677]	[1429,1532,1606,1724]	-4	hSpCas9	negative selection	5534834
68678180	68678203	16	-	27260156	BXPC3	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.33339199122815244	[1092]	[858,757,929,1114]	-6	hSpCas9	negative selection	5534835
68678262	68678285	16	-	27260156	BXPC3	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.43345257942057447	[231]	[349,323,330,296]	8	hSpCas9	negative selection	5534836
68678570	68678593	16	-	27260156	BXPC3	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.32809399182775556	[851]	[735,683,552,876]	-6	hSpCas9	negative selection	5599112
68678770	68678793	16	-	27260156	BXPC3	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	-0.0543055781348461	[394]	[335,404,419,438]	-1	hSpCas9	negative selection	5599113
68678608	68678631	16	+	27260156	BXPC3	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.4659787557292572	[221]	[160,142,208,159]	-7	hSpCas9	negative selection	5599114
68678820	68678843	16	-	27260156	A673	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.15533438000361555	[1677]	[2181,1645,1743,1702]	-4	hSpCas9	negative selection	5656085
68678180	68678203	16	-	27260156	A673	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.2433252580700419	[1092]	[1143,1027,1045,1227]	-5	hSpCas9	negative selection	5656086
68678262	68678285	16	-	27260156	A673	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.08507433536944553	[231]	[390,215,240,349]	2	hSpCas9	negative selection	5656087
68678570	68678593	16	-	27260156	A673	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.09394561547328106	[851]	[1006,964,966,894]	-2	hSpCas9	negative selection	5720363
68678770	68678793	16	-	27260156	A673	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	-0.03490504603546779	[394]	[490,391,429,547]	-1	hSpCas9	negative selection	5720364
68678608	68678631	16	+	27260156	A673	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.3688489744283676	[221]	[214,176,269,161]	-7	hSpCas9	negative selection	5720365
68678820	68678843	16	-	27260156	A375	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.46816102887983635	[1677]	[1359,1478,1572,1274]	-6	hSpCas9	negative selection	5777336
68678180	68678203	16	-	27260156	A375	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.30322390752698436	[1092]	[1414,1013,990,748]	-4	hSpCas9	negative selection	5777337
68678262	68678285	16	-	27260156	A375	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.3709286003132082	[231]	[362,416,420,223]	5	hSpCas9	negative selection	5777338
68678570	68678593	16	-	27260156	A375	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.17136847206355976	[851]	[963,1408,1123,1030]	2	hSpCas9	negative selection	5841614
68678770	68678793	16	-	27260156	A375	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.09820262238391494	[394]	[590,606,344,451]	1	hSpCas9	negative selection	5841615
68678608	68678631	16	+	27260156	A375	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.22908601757198177	[221]	[227,268,248,152]	-3	hSpCas9	negative selection	5841616
68678820	68678843	16	-	27260156	COLO741	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.10295535935300637	[1677]	[2050,2275,1685]	-2	hSpCas9	negative selection	5898587
68678180	68678203	16	-	27260156	COLO741	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.36813581537452866	[1092]	[1334,1090,855]	-7	hSpCas9	negative selection	5898588
68678262	68678285	16	-	27260156	COLO741	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.16488779452194569	[231]	[292,409,292]	3	hSpCas9	negative selection	5898589
68678570	68678593	16	-	27260156	COLO741	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.13346865753243353	[851]	[1213,1032,763]	-3	hSpCas9	negative selection	5962865
68678770	68678793	16	-	27260156	COLO741	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.12222107010542732	[394]	[601,470,575]	2	hSpCas9	negative selection	5962866
68678608	68678631	16	+	27260156	COLO741	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.38670930548875027	[221]	[255,199,198]	-7	hSpCas9	negative selection	5962867
68678820	68678843	16	-	27260156	CAL120	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	0.5302267593043801	[1677]	[2794,3250,2966]	7	hSpCas9	negative selection	6019838
68678180	68678203	16	-	27260156	CAL120	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.3910016962809828	[1092]	[1415,813,939]	-5	hSpCas9	negative selection	6019839
68678262	68678285	16	-	27260156	CAL120	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.34169222610189953	[231]	[346,517,231]	5	hSpCas9	negative selection	6019840
68678570	68678593	16	-	27260156	CAL120	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.11892709383252087	[851]	[779,928,1678]	1	hSpCas9	negative selection	6084116
68678770	68678793	16	-	27260156	CAL120	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	-0.1630608788259894	[394]	[480,506,336]	-2	hSpCas9	negative selection	6084117
68678608	68678631	16	+	27260156	CAL120	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.9822823142543806	[221]	[260,110,66]	-8	hSpCas9	negative selection	6084118
68678820	68678843	16	-	27260156	CADOES1	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.3187843567655728	[1677]	[1302,1331,1347,1012]	-5	hSpCas9	negative selection	6141089
68678180	68678203	16	-	27260156	CADOES1	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.25259011070516046	[1092]	[924,954,684,847]	-4	hSpCas9	negative selection	6141090
68678262	68678285	16	-	27260156	CADOES1	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.3899496279196054	[231]	[235,167,336,393]	6	hSpCas9	negative selection	6141091
68678570	68678593	16	-	27260156	CADOES1	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.020496878940099106	[851]	[597,768,755,1010]	0	hSpCas9	negative selection	6205367
68678770	68678793	16	-	27260156	CADOES1	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.03314769690862379	[394]	[395,285,429,391]	0	hSpCas9	negative selection	6205368
68678608	68678631	16	+	27260156	CADOES1	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	0.24009989504560858	[221]	[424,174,101,273]	4	hSpCas9	negative selection	6205369
68678820	68678843	16	-	27260156	EWS502	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	0.24337128048893808	[1677]	[2006,1997,2227,2198]	4	hSpCas9	negative selection	6262340
68678180	68678203	16	-	27260156	EWS502	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.1688090265367208	[1092]	[936,860,1219,1124]	-3	hSpCas9	negative selection	6262341
68678262	68678285	16	-	27260156	EWS502	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.5237295998391283	[231]	[413,227,323,449]	8	hSpCas9	negative selection	6262342
68678570	68678593	16	-	27260156	EWS502	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.21419967771658943	[851]	[673,755,755,947]	-4	hSpCas9	negative selection	6326618
68678770	68678793	16	-	27260156	EWS502	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	-0.1905005341376782	[394]	[365,295,392,416]	-3	hSpCas9	negative selection	6326619
68678608	68678631	16	+	27260156	EWS502	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.5525387082198869	[221]	[118,184,211,126]	-7	hSpCas9	negative selection	6326620
68678820	68678843	16	-	27260156	EW8	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.16084486647003082	[1677]	[1195,1019,1229,1409]	-3	hSpCas9	negative selection	6383591
68678180	68678203	16	-	27260156	EW8	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.06249489784967599	[1092]	[945,736,797,927]	-1	hSpCas9	negative selection	6383592
68678262	68678285	16	-	27260156	EW8	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.28553083711491845	[231]	[267,176,234,238]	5	hSpCas9	negative selection	6383593
68678570	68678593	16	-	27260156	EW8	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.07064875949991556	[851]	[806,664,578,606]	-1	hSpCas9	negative selection	6447869
68678770	68678793	16	-	27260156	EW8	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.24448006494017727	[394]	[496,231,384,412]	4	hSpCas9	negative selection	6447870
68678608	68678631	16	+	27260156	EW8	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.6737388850892339	[221]	[84,138,123,97]	-8	hSpCas9	negative selection	6447871
68678820	68678843	16	-	27260156	CORL105	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.24824835523938438	[1677]	[1762,1620,1718,1526]	-4	hSpCas9	negative selection	6504842
68678180	68678203	16	-	27260156	CORL105	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.3194182890730498	[1092]	[973,870,1151,1124]	-5	hSpCas9	negative selection	6504843
68678262	68678285	16	-	27260156	CORL105	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.426732407938191	[231]	[386,277,493,323]	7	hSpCas9	negative selection	6504844
68678570	68678593	16	-	27260156	CORL105	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.10806592668211068	[851]	[994,1055,1475,833]	2	hSpCas9	negative selection	6569120
68678770	68678793	16	-	27260156	CORL105	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.055424916902218735	[394]	[472,470,487,490]	1	hSpCas9	negative selection	6569121
68678608	68678631	16	+	27260156	CORL105	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.25507715252785923	[221]	[211,255,303,111]	-5	hSpCas9	negative selection	6569122
68678820	68678843	16	-	27260156	HS294T	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.5102154883818988	[1677]	[429,387,513,500]	-6	hSpCas9	negative selection	6626093
68678180	68678203	16	-	27260156	HS294T	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.4305179814183965	[1092]	[291,286,294,395]	-6	hSpCas9	negative selection	6626094
68678262	68678285	16	-	27260156	HS294T	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.9416006714834219	[231]	[116,198,99,297]	9	hSpCas9	negative selection	6626095
68678570	68678593	16	-	27260156	HS294T	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.14181575248407685	[851]	[349,285,294,557]	2	hSpCas9	negative selection	6690371
68678770	68678793	16	-	27260156	HS294T	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.8134315364330984	[394]	[220,357,282,200]	9	hSpCas9	negative selection	6690372
68678608	68678631	16	+	27260156	HS294T	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.38007896249533424	[221]	[54,104,48,51]	-5	hSpCas9	negative selection	6690373
68678820	68678843	16	-	27260156	HCC44	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.14982573137220645	[1677]	[2392,901,1942,1804]	-2	hSpCas9	negative selection	6747344
68678180	68678203	16	-	27260156	HCC44	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.4658111557395028	[1092]	[1320,803,883,622]	-6	hSpCas9	negative selection	6747345
68678262	68678285	16	-	27260156	HCC44	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.15268049020078656	[231]	[374,302,174,296]	2	hSpCas9	negative selection	6747346
68678570	68678593	16	-	27260156	HCC44	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.046771018112223395	[851]	[1089,987,991,914]	0	hSpCas9	negative selection	6811622
68678770	68678793	16	-	27260156	HCC44	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.15684571442799924	[394]	[667,361,682,346]	2	hSpCas9	negative selection	6811623
68678608	68678631	16	+	27260156	HCC44	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.3947282704093804	[221]	[185,167,224,191]	-6	hSpCas9	negative selection	6811624
68678820	68678843	16	-	27260156	G402	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.3378824126125295	[1677]	[1670,1556,1939,1323]	-4	hSpCas9	negative selection	6868595
68678180	68678203	16	-	27260156	G402	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.5665055367798448	[1092]	[1014,938,666,991]	-6	hSpCas9	negative selection	6868596
68678262	68678285	16	-	27260156	G402	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.3752780933132077	[231]	[466,358,451,210]	5	hSpCas9	negative selection	6868597
68678570	68678593	16	-	27260156	G402	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.1557264006202801	[851]	[1378,1203,1037,1046]	2	hSpCas9	negative selection	6932873
68678770	68678793	16	-	27260156	G402	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.21599558582830583	[394]	[497,537,420,759]	2	hSpCas9	negative selection	6932874
68678608	68678631	16	+	27260156	G402	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-1.1635818879729773	[221]	[126,91,69,189]	-8	hSpCas9	negative selection	6932875
68678820	68678843	16	-	27260156	L33	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.06801257107067649	[1677]	[1539,573,1039,1806]	-1	hSpCas9	negative selection	6989846
68678180	68678203	16	-	27260156	L33	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.3960272804606675	[1092]	[729,327,552,913]	-7	hSpCas9	negative selection	6989847
68678262	68678285	16	-	27260156	L33	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.37586474105404744	[231]	[364,113,174,280]	7	hSpCas9	negative selection	6989848
68678570	68678593	16	-	27260156	L33	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.08516393922700927	[851]	[912,307,515,724]	-2	hSpCas9	negative selection	7054124
68678770	68678793	16	-	27260156	L33	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	-0.3188873606201503	[394]	[373,85,209,346]	-6	hSpCas9	negative selection	7054125
68678608	68678631	16	+	27260156	L33	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.4915928756640955	[221]	[114,69,105,177]	-8	hSpCas9	negative selection	7054126
68678820	68678843	16	-	27260156	K562	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	0.31298978328308413	[1677]	[1022,4681,769,1087]	4	hSpCas9	negative selection	7111097
68678180	68678203	16	-	27260156	K562	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.27795437832919234	[1092]	[890,911,730,688]	-3	hSpCas9	negative selection	7111098
68678262	68678285	16	-	27260156	K562	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.3136499448261574	[231]	[422,236,202,180]	4	hSpCas9	negative selection	7111099
68678570	68678593	16	-	27260156	K562	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.0566662882025023	[851]	[841,558,509,965]	0	hSpCas9	negative selection	7175375
68678770	68678793	16	-	27260156	K562	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.22527307910922278	[394]	[402,320,383,511]	3	hSpCas9	negative selection	7175376
68678608	68678631	16	+	27260156	K562	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.4252534299836854	[221]	[277,215,38,75]	-5	hSpCas9	negative selection	7175377
68678820	68678843	16	-	27260156	HT29	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.055160367804832244	[1677]	[1883,2055,2137,1784]	-1	hSpCas9	negative selection	7232348
68678180	68678203	16	-	27260156	HT29	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.17852233329500167	[1092]	[1435,1175,1138,980]	-4	hSpCas9	negative selection	7232349
68678262	68678285	16	-	27260156	HT29	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.3572206080705267	[231]	[248,380,457,348]	7	hSpCas9	negative selection	7232350
68678570	68678593	16	-	27260156	HT29	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.07814870872332591	[851]	[1403,1056,955,982]	1	hSpCas9	negative selection	7296626
68678770	68678793	16	-	27260156	HT29	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.029460891371240944	[394]	[540,573,471,392]	0	hSpCas9	negative selection	7296627
68678608	68678631	16	+	27260156	HT29	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.42413951085598733	[221]	[232,197,215,162]	-7	hSpCas9	negative selection	7296628
68678820	68678843	16	-	27260156	MHHES1	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	0.12906624911061382	[1677]	[2462,1877,2187,1785]	2	hSpCas9	negative selection	7353599
68678180	68678203	16	-	27260156	MHHES1	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	0.013175791487157529	[1092]	[1542,1370,1311,855]	0	hSpCas9	negative selection	7353600
68678262	68678285	16	-	27260156	MHHES1	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.3087141744341202	[231]	[465,349,333,188]	5	hSpCas9	negative selection	7353601
68678570	68678593	16	-	27260156	MHHES1	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.14746236975245353	[851]	[1089,1177,1053,946]	2	hSpCas9	negative selection	7417877
68678770	68678793	16	-	27260156	MHHES1	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.34622894081993216	[394]	[645,549,577,498]	6	hSpCas9	negative selection	7417878
68678608	68678631	16	+	27260156	MHHES1	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.4667203079848632	[221]	[248,148,214,124]	-7	hSpCas9	negative selection	7417879
68678820	68678843	16	-	27260156	MEWO	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	0.03751573540138131	[1677]	[1968,1538,1394]	0	hSpCas9	negative selection	7474850
68678180	68678203	16	-	27260156	MEWO	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.04059126565965565	[1092]	[1252,894,884]	-1	hSpCas9	negative selection	7474851
68678262	68678285	16	-	27260156	MEWO	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	-0.37793729545082044	[231]	[186,149,167]	-7	hSpCas9	negative selection	7474852
68678570	68678593	16	-	27260156	MEWO	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.06828970166730941	[851]	[1071,588,892]	1	hSpCas9	negative selection	7539128
68678770	68678793	16	-	27260156	MEWO	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	-0.08556097372360827	[394]	[454,225,384]	-2	hSpCas9	negative selection	7539129
68678608	68678631	16	+	27260156	MEWO	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.4818547897345029	[221]	[178,147,124]	-8	hSpCas9	negative selection	7539130
68678820	68678843	16	-	27260156	LNCAPCLONEFGC	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.23813128800933425	[1677]	[1282,1158,1424,1315]	-4	hSpCas9	negative selection	7596101
68678180	68678203	16	-	27260156	LNCAPCLONEFGC	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.34435518553509636	[1092]	[741,748,1064,607]	-5	hSpCas9	negative selection	7596102
68678262	68678285	16	-	27260156	LNCAPCLONEFGC	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.6257410531573862	[231]	[300,374,283,327]	8	hSpCas9	negative selection	7596103
68678570	68678593	16	-	27260156	LNCAPCLONEFGC	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.008363815333661595	[851]	[794,692,730,883]	0	hSpCas9	negative selection	7660379
68678770	68678793	16	-	27260156	LNCAPCLONEFGC	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.16681733508488378	[394]	[390,405,486,334]	2	hSpCas9	negative selection	7660380
68678608	68678631	16	+	27260156	LNCAPCLONEFGC	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.863473277221837	[221]	[83,141,140,77]	-8	hSpCas9	negative selection	7660381
68678820	68678843	16	-	27260156	PANC0327	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.4712925683411324	[1677]	[1295,1164,1023,821]	-6	hSpCas9	negative selection	7717352
68678180	68678203	16	-	27260156	PANC0327	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.6452248837021995	[1092]	[560,582,652,685]	-7	hSpCas9	negative selection	7717353
68678262	68678285	16	-	27260156	PANC0327	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.7252198669758944	[231]	[322,254,251,541]	9	hSpCas9	negative selection	7717354
68678570	68678593	16	-	27260156	PANC0327	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.07701034491058112	[851]	[554,676,907,721]	-1	hSpCas9	negative selection	7781630
68678770	68678793	16	-	27260156	PANC0327	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	-0.28807500506194456	[394]	[283,256,281,329]	-4	hSpCas9	negative selection	7781631
68678608	68678631	16	+	27260156	PANC0327	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.44904166940900403	[221]	[236,107,96,147]	-6	hSpCas9	negative selection	7781632
68678820	68678843	16	-	27260156	NCIH2009	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.28994629111123893	[1677]	[2279,1979,1559]	-4	hSpCas9	negative selection	7838603
68678180	68678203	16	-	27260156	NCIH2009	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.39160390903642717	[1092]	[1225,1245,1028]	-5	hSpCas9	negative selection	7838604
68678262	68678285	16	-	27260156	NCIH2009	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.5640222445532939	[231]	[671,418,384]	7	hSpCas9	negative selection	7838605
68678570	68678593	16	-	27260156	NCIH2009	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.016931816253218934	[851]	[1342,963,1335]	0	hSpCas9	negative selection	7902881
68678770	68678793	16	-	27260156	NCIH2009	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.4110804072142118	[394]	[847,776,596]	5	hSpCas9	negative selection	7902882
68678608	68678631	16	+	27260156	NCIH2009	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.06412203850369869	[221]	[283,243,359]	-1	hSpCas9	negative selection	7902883
68678820	68678843	16	-	27260156	NCIH1373	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	0.6576151764565861	[1677]	[2993,2362,3775,724]	6	hSpCas9	negative selection	7959854
68678180	68678203	16	-	27260156	NCIH1373	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.4676631153743428	[1092]	[943,681,871,284]	-5	hSpCas9	negative selection	7959855
68678262	68678285	16	-	27260156	NCIH1373	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.8886333571431319	[231]	[257,460,830,84]	8	hSpCas9	negative selection	7959856
68678570	68678593	16	-	27260156	NCIH1373	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.21414621639305143	[851]	[1526,958,794,325]	2	hSpCas9	negative selection	8024132
68678770	68678793	16	-	27260156	NCIH1373	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.33010141602453014	[394]	[425,584,627,146]	3	hSpCas9	negative selection	8024133
68678608	68678631	16	+	27260156	NCIH1373	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.8884418405139198	[221]	[88,154,93,50]	-7	hSpCas9	negative selection	8024134
68678820	68678843	16	-	27260156	PATU8902	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.739683568065634	[1677]	[1049,1492,1370,1723]	-6	hSpCas9	negative selection	8081105
68678180	68678203	16	-	27260156	PATU8902	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.4225071282967454	[1092]	[1053,1275,1108,1098]	-4	hSpCas9	negative selection	8081106
68678262	68678285	16	-	27260156	PATU8902	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.385330574174664	[231]	[641,552,98,478]	4	hSpCas9	negative selection	8081107
68678570	68678593	16	-	27260156	PATU8902	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.2891734519961986	[851]	[949,1700,1047,2302]	3	hSpCas9	negative selection	8145383
68678770	68678793	16	-	27260156	PATU8902	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.5709725984502643	[394]	[1132,1049,533,587]	6	hSpCas9	negative selection	8145384
68678608	68678631	16	+	27260156	PATU8902	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.8729951197631345	[221]	[159,159,57,345]	-7	hSpCas9	negative selection	8145385
68678820	68678843	16	-	27260156	PANC1	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.09892631276422392	[1677]	[1376,1795,1500,860]	-2	hSpCas9	negative selection	8202356
68678180	68678203	16	-	27260156	PANC1	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.2070468697358765	[1092]	[850,948,941,566]	-3	hSpCas9	negative selection	8202357
68678262	68678285	16	-	27260156	PANC1	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.43794301403531166	[231]	[365,284,251,186]	7	hSpCas9	negative selection	8202358
68678570	68678593	16	-	27260156	PANC1	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.015941823431517843	[851]	[802,776,767,624]	0	hSpCas9	negative selection	8266634
68678770	68678793	16	-	27260156	PANC1	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.16175825849349879	[394]	[292,441,433,360]	2	hSpCas9	negative selection	8266635
68678608	68678631	16	+	27260156	PANC1	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.956231870578623	[221]	[74,115,101,101]	-8	hSpCas9	negative selection	8266636
68678820	68678843	16	-	27260156	PANC0813	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.06757614003719747	[1677]	[1543,2256,1522,2147]	-1	hSpCas9	negative selection	8323607
68678180	68678203	16	-	27260156	PANC0813	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.08525182758276384	[1092]	[1233,1068,1367,1172]	-1	hSpCas9	negative selection	8323608
68678262	68678285	16	-	27260156	PANC0813	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.6926670933223456	[231]	[397,428,413,511]	9	hSpCas9	negative selection	8323609
68678570	68678593	16	-	27260156	PANC0813	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.020997686028570994	[851]	[1027,1011,1105,811]	0	hSpCas9	negative selection	8387885
68678770	68678793	16	-	27260156	PANC0813	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.18017560564763974	[394]	[550,771,428,360]	3	hSpCas9	negative selection	8387886
68678608	68678631	16	+	27260156	PANC0813	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.18660839572568522	[221]	[175,214,264,253]	-3	hSpCas9	negative selection	8387887
68678820	68678843	16	-	27260156	RDES	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.43058103575160045	[1677]	[1169,1398,1468,1755]	-6	hSpCas9	negative selection	8444858
68678180	68678203	16	-	27260156	RDES	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.38383308483872813	[1092]	[713,758,977,1537]	-6	hSpCas9	negative selection	8444859
68678262	68678285	16	-	27260156	RDES	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.3759816191113703	[231]	[351,389,372,235]	6	hSpCas9	negative selection	8444860
68678570	68678593	16	-	27260156	RDES	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.14670132067932495	[851]	[704,972,748,1151]	-2	hSpCas9	negative selection	8509136
68678770	68678793	16	-	27260156	RDES	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.19335466690664063	[394]	[427,417,747,503]	3	hSpCas9	negative selection	8509137
68678608	68678631	16	+	27260156	RDES	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.7335678420860869	[221]	[117,154,166,181]	-8	hSpCas9	negative selection	8509138
68678820	68678843	16	-	27260156	PC3	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.13791892965590047	[1677]	[1090,1406,2523,1474]	-3	hSpCas9	negative selection	8566109
68678180	68678203	16	-	27260156	PC3	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.12020591070712072	[1092]	[583,1101,1706,974]	-3	hSpCas9	negative selection	8566110
68678262	68678285	16	-	27260156	PC3	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.5001190134488213	[231]	[206,244,601,389]	8	hSpCas9	negative selection	8566111
68678570	68678593	16	-	27260156	PC3	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.06747553778027782	[851]	[524,725,1942,863]	1	hSpCas9	negative selection	8630387
68678770	68678793	16	-	27260156	PC3	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	-0.04045880904725807	[394]	[127,489,719,408]	-1	hSpCas9	negative selection	8630388
68678608	68678631	16	+	27260156	PC3	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.2924718934108461	[221]	[62,191,272,274]	-6	hSpCas9	negative selection	8630389
68678820	68678843	16	-	27260156	PATU8988T	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	0.25379337793892054	[1677]	[2139,1593,1619,2387]	4	hSpCas9	negative selection	8687360
68678180	68678203	16	-	27260156	PATU8988T	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.24197045005460227	[1092]	[862,887,1026,782]	-4	hSpCas9	negative selection	8687361
68678262	68678285	16	-	27260156	PATU8988T	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.8433475975394461	[231]	[475,328,385,411]	9	hSpCas9	negative selection	8687362
68678570	68678593	16	-	27260156	PATU8988T	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.04562436218829258	[851]	[700,815,769,914]	-1	hSpCas9	negative selection	8751638
68678770	68678793	16	-	27260156	PATU8988T	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.09663199508412298	[394]	[416,582,331,309]	1	hSpCas9	negative selection	8751639
68678608	68678631	16	+	27260156	PATU8988T	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.275349653121568	[221]	[55,202,97,370]	-5	hSpCas9	negative selection	8751640
68678820	68678843	16	-	27260156	T47D	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.3263523584791841	[1677]	[1605,1439,1682,1513]	-6	hSpCas9	negative selection	8808611
68678180	68678203	16	-	27260156	T47D	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.3026905882863745	[1092]	[1161,963,1106,896]	-6	hSpCas9	negative selection	8808612
68678262	68678285	16	-	27260156	T47D	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.1557230474066631	[231]	[337,221,298,353]	3	hSpCas9	negative selection	8808613
68678570	68678593	16	-	27260156	T47D	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.1887344042734932	[851]	[766,874,719,1130]	-4	hSpCas9	negative selection	8872889
68678770	68678793	16	-	27260156	T47D	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	-0.03687734107565471	[394]	[513,450,425,401]	-1	hSpCas9	negative selection	8872890
68678608	68678631	16	+	27260156	T47D	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.32501398688530414	[221]	[239,195,187,202]	-6	hSpCas9	negative selection	8872891
68678820	68678843	16	-	27260156	SU8686	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	0.1717413299379067	[1677]	[1657,1666,2002,2273]	3	hSpCas9	negative selection	8929862
68678180	68678203	16	-	27260156	SU8686	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.1675683368974108	[1092]	[782,927,955,1257]	-3	hSpCas9	negative selection	8929863
68678262	68678285	16	-	27260156	SU8686	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.6443751604726963	[231]	[283,306,360,525]	9	hSpCas9	negative selection	8929864
68678570	68678593	16	-	27260156	SU8686	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.0027971356726641528	[851]	[730,760,1044,860]	0	hSpCas9	negative selection	8994140
68678770	68678793	16	-	27260156	SU8686	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.1251319654166927	[394]	[484,345,319,579]	2	hSpCas9	negative selection	8994141
68678608	68678631	16	+	27260156	SU8686	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.22984614923217817	[221]	[223,80,189,278]	-4	hSpCas9	negative selection	8994142
68678820	68678843	16	-	27260156	SKES1	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	0.023086582280345214	[1677]	[1983,1755,1702,1421]	0	hSpCas9	negative selection	9051113
68678180	68678203	16	-	27260156	SKES1	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.09270057691606759	[1092]	[1316,1138,850,849]	-2	hSpCas9	negative selection	9051114
68678262	68678285	16	-	27260156	SKES1	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.32768509377795874	[231]	[385,264,272,249]	7	hSpCas9	negative selection	9051115
68678570	68678593	16	-	27260156	SKES1	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.22042701510103657	[851]	[716,888,807,535]	-5	hSpCas9	negative selection	9115391
68678770	68678793	16	-	27260156	SKES1	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	-0.12756697249602056	[394]	[509,403,409,163]	-3	hSpCas9	negative selection	9115392
68678608	68678631	16	+	27260156	SKES1	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.6281443208327235	[221]	[189,237,59,106]	-8	hSpCas9	negative selection	9115393
68678820	68678843	16	-	27260156	TOV112D	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.1293623358535787	[1677]	[1711,1704,1297,1485]	-3	hSpCas9	negative selection	9172364
68678180	68678203	16	-	27260156	TOV112D	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.057885644938862724	[1092]	[1280,1207,1170,614]	-1	hSpCas9	negative selection	9172365
68678262	68678285	16	-	27260156	TOV112D	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.4549487342872546	[231]	[350,316,330,277]	8	hSpCas9	negative selection	9172366
68678570	68678593	16	-	27260156	TOV112D	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.09000725481320437	[851]	[1034,1176,648,848]	1	hSpCas9	negative selection	9236642
68678770	68678793	16	-	27260156	TOV112D	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.2334979615121951	[394]	[338,793,512,288]	4	hSpCas9	negative selection	9236643
68678608	68678631	16	+	27260156	TOV112D	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.1885676445423623	[221]	[152,243,211,179]	-4	hSpCas9	negative selection	9236644
68678820	68678843	16	-	27260156	TC71	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.0901243983320561	[1677]	[1723,1701,1541,1801]	-2	hSpCas9	negative selection	9293615
68678180	68678203	16	-	27260156	TC71	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.10821904730033816	[1092]	[1078,1102,1070,1095]	-3	hSpCas9	negative selection	9293616
68678262	68678285	16	-	27260156	TC71	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	-0.04247179601421447	[231]	[277,263,212,208]	-1	hSpCas9	negative selection	9293617
68678570	68678593	16	-	27260156	TC71	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	-0.017694812906656532	[851]	[923,990,879,807]	0	hSpCas9	negative selection	9357893
68678770	68678793	16	-	27260156	TC71	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	-0.10692993258191036	[394]	[265,461,407,441]	-3	hSpCas9	negative selection	9357894
68678608	68678631	16	+	27260156	TC71	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.45267023301755627	[221]	[160,198,183,149]	-8	hSpCas9	negative selection	9357895
68678820	68678843	16	-	27260156	TC32	viability	ATTCTGGTCGGTCACGATGATGG	CDH3	ENSG00000062038	-0.06706198590553192	[1677]	[1262,1184,2162,1591]	-1	hSpCas9	negative selection	9414866
68678180	68678203	16	-	27260156	TC32	viability	GTGTCTTCGTAAGATACGTTTGG	CDH3	ENSG00000062038	-0.3630383894953234	[1092]	[785,414,1138,1029]	-6	hSpCas9	negative selection	9414867
68678262	68678285	16	-	27260156	TC32	viability	GTCGTACCTGATTCAGTCTCTGG	CDH3	ENSG00000062038	0.11673102812368241	[231]	[266,175,269,242]	2	hSpCas9	negative selection	9414868
68678570	68678593	16	-	27260156	TC32	viability	TCTACAGCGAAGACACCCTCAGG	CDH3	ENSG00000062038	0.05355876948344096	[851]	[680,827,1051,763]	1	hSpCas9	negative selection	9479144
68678770	68678793	16	-	27260156	TC32	viability	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.08267410823953075	[394]	[479,177,495,489]	1	hSpCas9	negative selection	9479145
68678608	68678631	16	+	27260156	TC32	viability	GTTGTTGTTGAATAAGCCACTGG	CDH3	ENSG00000062038	-0.1002912021763056	[221]	[148,143,291,225]	-2	hSpCas9	negative selection	9479146
68676435	68676458	16	+	27869803	HPAFII	viability after 27 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	1.3966770806053679	[74]	[189,31,NaN]	9	hSpCas9	negative selection	9558119
68678575	68678598	16	+	27869803	HPAFII	viability after 27 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.4116918540183976	[227]	[147,168,NaN]	3	hSpCas9	negative selection	9558120
68678770	68678793	16	-	27869803	HPAFII	viability after 27 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.6140809815589218	[383]	[422,213,NaN]	5	hSpCas9	negative selection	9558121
68679837	68679860	16	+	27869803	HPAFII	viability after 27 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	0.228765697969258	[241]	[27,249,NaN]	1	hSpCas9	negative selection	9558122
68676435	68676458	16	+	27869803	HPAFII	viability after 15 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	0.9878122562860081	[74]	[194,137,NaN]	9	hSpCas9	negative selection	9640568
68678575	68678598	16	+	27869803	HPAFII	viability after 15 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.35535976484059373	[227]	[265,342,NaN]	4	hSpCas9	negative selection	9640569
68678770	68678793	16	-	27869803	HPAFII	viability after 15 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.5880835796200418	[383]	[813,499,NaN]	6	hSpCas9	negative selection	9640570
68679837	68679860	16	+	27869803	HPAFII	viability after 15 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	-0.21713352097710734	[241]	[158,263,NaN]	-2	hSpCas9	negative selection	9640571
68676435	68676458	16	+	27869803	ASPC1	viability after 36 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	0.8182839334763155	[352]	[334,48,265]	7	hSpCas9	negative selection	9723017
68678575	68678598	16	+	27869803	ASPC1	viability after 36 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	-0.6754567701367419	[494]	[126,73,120]	-6	hSpCas9	negative selection	9723018
68678770	68678793	16	-	27869803	ASPC1	viability after 36 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.18666452929767718	[819]	[515,239,256]	1	hSpCas9	negative selection	9723019
68679837	68679860	16	+	27869803	ASPC1	viability after 36 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	0.7747593409742355	[568]	[257,613,175]	7	hSpCas9	negative selection	9723020
68676435	68676458	16	+	27869803	PATU8988S	viability after 35 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	-0.16167789252212128	[332]	[74,164,NaN]	-2	hSpCas9	negative selection	9805466
68678575	68678598	16	+	27869803	PATU8988S	viability after 35 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	-0.4337723753491409	[445]	[124,140,NaN]	-4	hSpCas9	negative selection	9805467
68678770	68678793	16	-	27869803	PATU8988S	viability after 35 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.03669472832431775	[996]	[361,461,NaN]	0	hSpCas9	negative selection	9805468
68679837	68679860	16	+	27869803	PATU8988S	viability after 35 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	-0.6037811405733162	[467]	[136,110,NaN]	-6	hSpCas9	negative selection	9805469
68676435	68676458	16	+	27869803	PATU8988S	viability after 31 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	-0.2933362070637795	[332]	[66,160,NaN]	-3	hSpCas9	negative selection	9887915
68678575	68678598	16	+	27869803	PATU8988S	viability after 31 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	-0.15074729747941545	[445]	[135,190,NaN]	-2	hSpCas9	negative selection	9887916
68678770	68678793	16	-	27869803	PATU8988S	viability after 31 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.1422448511409251	[996]	[348,552,NaN]	1	hSpCas9	negative selection	9887917
68679837	68679860	16	+	27869803	PATU8988S	viability after 31 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	-0.5616670549142728	[467]	[92,168,NaN]	-6	hSpCas9	negative selection	9887918
68676435	68676458	16	+	27869803	HPAFII	viability after 35 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	1.92188748275632	[74]	[236,38,NaN]	9	hSpCas9	negative selection	9970364
68678575	68678598	16	+	27869803	HPAFII	viability after 35 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.8553293690508813	[227]	[205,211,NaN]	5	hSpCas9	negative selection	9970365
68678770	68678793	16	-	27869803	HPAFII	viability after 35 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.5672094436878964	[383]	[351,215,NaN]	3	hSpCas9	negative selection	9970366
68679837	68679860	16	+	27869803	HPAFII	viability after 35 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	0.031152093057867182	[241]	[24,237,NaN]	0	hSpCas9	negative selection	9970367
68676435	68676458	16	+	27869803	HPAFII	viability after 31 days	GATGACTTCACTGTGCGGAATGG	CDH3	ENSG00000062038	1.429102174379691	[74]	[187,31,NaN]	9	hSpCas9	negative selection	10052813
68678575	68678598	16	+	27869803	HPAFII	viability after 31 days	GGGTGTCTTCGCTGTAGAGAAGG	CDH3	ENSG00000062038	0.35884981591103604	[227]	[154,173,NaN]	2	hSpCas9	negative selection	10052814
68678770	68678793	16	-	27869803	HPAFII	viability after 31 days	CACCATTCTCTGACACAGCGTGG	CDH3	ENSG00000062038	0.6765893836069589	[383]	[376,308,NaN]	5	hSpCas9	negative selection	10052815
68679837	68679860	16	+	27869803	HPAFII	viability after 31 days	GATGCCATCTACACCTACAATGG	CDH3	ENSG00000062038	-0.1624617393355652	[241]	[50,197,NaN]	-1	hSpCas9	negative selection	10052816
68691828	68691851	16	-	28162770	P31FUJ	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	-0.12237821472072796	[87]	[94]	-1	hSpCas9	negative selection	10130412
68678130	68678153	16	+	28162770	P31FUJ	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	0.44302309493792347	[240]	[384]	5	hSpCas9	negative selection	10130413
68678617	68678640	16	+	28162770	P31FUJ	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	0.8984423288638738	[62]	[137]	8	hSpCas9	negative selection	10130414
68678859	68678882	16	+	28162770	P31FUJ	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	0.09044281894497441	[875]	[1095]	0	hSpCas9	negative selection	10130415
68684761	68684784	16	-	28162770	P31FUJ	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-0.925478522435788	[138]	[85]	-6	hSpCas9	negative selection	10130416
68687524	68687547	16	-	28162770	P31FUJ	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	0.19472623904766195	[344]	[463]	2	hSpCas9	negative selection	10130417
68687668	68687691	16	-	28162770	P31FUJ	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-3.196276328389265	[155]	[19]	-9	hSpCas9	negative selection	10130418
68691828	68691851	16	-	28162770	TF1	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10299778
68678130	68678153	16	+	28162770	TF1	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	NaN	[NaN]	[197]	1	hSpCas9	negative selection	10299779
68678617	68678640	16	+	28162770	TF1	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	NaN	[NaN]	[211]	1	hSpCas9	negative selection	10299780
68678859	68678882	16	+	28162770	TF1	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	NaN	[NaN]	[735]	1	hSpCas9	negative selection	10299781
68684761	68684784	16	-	28162770	TF1	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10299782
68687524	68687547	16	-	28162770	TF1	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	NaN	[NaN]	[520]	1	hSpCas9	negative selection	10299783
68687668	68687691	16	-	28162770	TF1	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10299784
68691828	68691851	16	-	28162770	SKM1	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	-0.7631080089684368	[23]	[24]	-5	hSpCas9	negative selection	10469144
68678130	68678153	16	+	28162770	SKM1	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	0.2654611432283339	[79]	[169]	2	hSpCas9	negative selection	10469145
68678617	68678640	16	+	28162770	SKM1	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	0.7398771895861096	[20]	[61]	7	hSpCas9	negative selection	10469146
68678859	68678882	16	+	28162770	SKM1	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	-0.5671877989931802	[175]	[209]	-4	hSpCas9	negative selection	10469147
68684761	68684784	16	-	28162770	SKM1	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-0.722466024471091	[27]	[29]	-5	hSpCas9	negative selection	10469148
68687524	68687547	16	-	28162770	SKM1	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	0.5316352565926948	[89]	[229]	5	hSpCas9	negative selection	10469149
68687668	68687691	16	-	28162770	SKM1	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-2.6293566200796095	[34]	[9]	-9	hSpCas9	negative selection	10469150
68691828	68691851	16	-	28162770	SKM1	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	-0.7631080089684368	[23]	[24]	-5	hSpCas9	negative selection	10638510
68678130	68678153	16	+	28162770	SKM1	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	0.2654611432283339	[79]	[169]	2	hSpCas9	negative selection	10638511
68678617	68678640	16	+	28162770	SKM1	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	0.7398771895861096	[20]	[61]	7	hSpCas9	negative selection	10638512
68678859	68678882	16	+	28162770	SKM1	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	-0.5671877989931802	[175]	[209]	-4	hSpCas9	negative selection	10638513
68684761	68684784	16	-	28162770	SKM1	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-0.722466024471091	[27]	[29]	-5	hSpCas9	negative selection	10638514
68687524	68687547	16	-	28162770	SKM1	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	0.5316352565926948	[89]	[229]	5	hSpCas9	negative selection	10638515
68687668	68687691	16	-	28162770	SKM1	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-2.6293566200796095	[34]	[9]	-9	hSpCas9	negative selection	10638516
68691828	68691851	16	-	28162770	PL21	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	-0.8543081695330561	[53]	[12]	-5	hSpCas9	negative selection	10807876
68678130	68678153	16	+	28162770	PL21	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	-0.2296262219400783	[360]	[133]	-2	hSpCas9	negative selection	10807877
68678617	68678640	16	+	28162770	PL21	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	0.4307525426307366	[74]	[43]	4	hSpCas9	negative selection	10807878
68678859	68678882	16	+	28162770	PL21	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	0.2107477140553009	[541]	[272]	1	hSpCas9	negative selection	10807879
68684761	68684784	16	-	28162770	PL21	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-1.0477878989542653	[113]	[23]	-6	hSpCas9	negative selection	10807880
68687524	68687547	16	-	28162770	PL21	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	1.6065226484576256	[208]	[276]	9	hSpCas9	negative selection	10807881
68687668	68687691	16	-	28162770	PL21	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-1.186883508619927	[67]	[12]	-7	hSpCas9	negative selection	10807882
68691828	68691851	16	-	28162770	P31FUJ	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	-0.12237821472072796	[87]	[94]	-1	hSpCas9	negative selection	10977242
68678130	68678153	16	+	28162770	P31FUJ	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	0.44302309493792347	[240]	[384]	5	hSpCas9	negative selection	10977243
68678617	68678640	16	+	28162770	P31FUJ	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	0.8984423288638738	[62]	[137]	8	hSpCas9	negative selection	10977244
68678859	68678882	16	+	28162770	P31FUJ	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	0.09044281894497441	[875]	[1095]	0	hSpCas9	negative selection	10977245
68684761	68684784	16	-	28162770	P31FUJ	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-0.925478522435788	[138]	[85]	-6	hSpCas9	negative selection	10977246
68687524	68687547	16	-	28162770	P31FUJ	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	0.19472623904766195	[344]	[463]	2	hSpCas9	negative selection	10977247
68687668	68687691	16	-	28162770	P31FUJ	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-3.196276328389265	[155]	[19]	-9	hSpCas9	negative selection	10977248
68691828	68691851	16	-	28162770	OCIAML5	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	0.5937331821855341	[28]	[78]	5	hSpCas9	negative selection	11146608
68678130	68678153	16	+	28162770	OCIAML5	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	1.27762450577564	[100]	[441]	9	hSpCas9	negative selection	11146609
68678617	68678640	16	+	28162770	OCIAML5	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	0.504418746059734	[65]	[168]	4	hSpCas9	negative selection	11146610
68678859	68678882	16	+	28162770	OCIAML5	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	-0.015433856284146952	[438]	[783]	0	hSpCas9	negative selection	11146611
68684761	68684784	16	-	28162770	OCIAML5	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-3.173994665751359	[64]	[12]	-9	hSpCas9	negative selection	11146612
68687524	68687547	16	-	28162770	OCIAML5	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	0.09005251305550321	[177]	[341]	0	hSpCas9	negative selection	11146613
68687668	68687691	16	-	28162770	OCIAML5	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-4.388119471104207	[57]	[4]	-9	hSpCas9	negative selection	11146614
68691828	68691851	16	-	28162770	EOL1	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	0.008939958860907149	[82]	[43]	0	hSpCas9	negative selection	11315974
68678130	68678153	16	+	28162770	EOL1	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	-0.25586063385296365	[586]	[258]	-2	hSpCas9	negative selection	11315975
68678617	68678640	16	+	28162770	EOL1	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	0.5446140732476068	[202]	[155]	5	hSpCas9	negative selection	11315976
68678859	68678882	16	+	28162770	EOL1	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	0.09350562472906443	[828]	[465]	0	hSpCas9	negative selection	11315977
68684761	68684784	16	-	28162770	EOL1	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-0.8039063227401542	[168]	[50]	-5	hSpCas9	negative selection	11315978
68687524	68687547	16	-	28162770	EOL1	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	0.6604861709330129	[280]	[233]	6	hSpCas9	negative selection	11315979
68687668	68687691	16	-	28162770	EOL1	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-1.7869471350795534	[130]	[19]	-8	hSpCas9	negative selection	11315980
68691828	68691851	16	-	28162770	MOLM13	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	0.9939581932121665	[99]	[143]	7	hSpCas9	negative selection	11485340
68678130	68678153	16	+	28162770	MOLM13	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	0.5250630899318128	[469]	[488]	4	hSpCas9	negative selection	11485341
68678617	68678640	16	+	28162770	MOLM13	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	0.14596128665721642	[114]	[91]	1	hSpCas9	negative selection	11485342
68678859	68678882	16	+	28162770	MOLM13	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	-0.9260585123524103	[995]	[378]	-5	hSpCas9	negative selection	11485343
68684761	68684784	16	-	28162770	MOLM13	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-3.7724249477891316	[188]	[9]	-9	hSpCas9	negative selection	11485344
68687524	68687547	16	-	28162770	MOLM13	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	0.6948257280259748	[316]	[370]	5	hSpCas9	negative selection	11485345
68687668	68687691	16	-	28162770	MOLM13	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-6.175966808230147	[99]	[0]	-9	hSpCas9	negative selection	11485346
68691828	68691851	16	-	28162770	HEL	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	0.34634582922013224	[69]	[56]	3	hSpCas9	negative selection	11654706
68678130	68678153	16	+	28162770	HEL	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	0.5325559142499339	[407]	[377]	4	hSpCas9	negative selection	11654707
68678617	68678640	16	+	28162770	HEL	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	0.3083197929297975	[115]	[91]	2	hSpCas9	negative selection	11654708
68678859	68678882	16	+	28162770	HEL	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	0.15572138169116023	[725]	[517]	1	hSpCas9	negative selection	11654709
68684761	68684784	16	-	28162770	HEL	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-2.2641517636081616	[164]	[21]	-8	hSpCas9	negative selection	11654710
68687524	68687547	16	-	28162770	HEL	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	0.9938132725472357	[195]	[249]	8	hSpCas9	negative selection	11654711
68687668	68687691	16	-	28162770	HEL	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-6.138620881524303	[109]	[0]	-9	hSpCas9	negative selection	11654712
68691828	68691851	16	-	28162770	MV411	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	-0.11513252860193313	[71]	[55]	-1	hSpCas9	negative selection	11824072
68678130	68678153	16	+	28162770	MV411	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	0.4141742745940403	[301]	[338]	3	hSpCas9	negative selection	11824073
68678617	68678640	16	+	28162770	MV411	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	-0.9576768791218369	[82]	[35]	-6	hSpCas9	negative selection	11824074
68678859	68678882	16	+	28162770	MV411	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	-0.34288813470547375	[538]	[357]	-3	hSpCas9	negative selection	11824075
68684761	68684784	16	-	28162770	MV411	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-0.14770039105836363	[95]	[72]	-1	hSpCas9	negative selection	11824076
68687524	68687547	16	-	28162770	MV411	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	0.4776353746080236	[236]	[277]	4	hSpCas9	negative selection	11824077
68687668	68687691	16	-	28162770	MV411	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-2.4843663382676517	[92]	[13]	-8	hSpCas9	negative selection	11824078
68691828	68691851	16	-	28162770	MONOMAC1	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	0.9354134489640957	[25]	[56]	8	hSpCas9	negative selection	11993438
68678130	68678153	16	+	28162770	MONOMAC1	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	0.35877930800208613	[199]	[293]	3	hSpCas9	negative selection	11993439
68678617	68678640	16	+	28162770	MONOMAC1	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	2.713855679106461	[47]	[360]	9	hSpCas9	negative selection	11993440
68678859	68678882	16	+	28162770	MONOMAC1	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	0.3477685271896198	[339]	[495]	3	hSpCas9	negative selection	11993441
68684761	68684784	16	-	28162770	MONOMAC1	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-1.9519243492230223	[107]	[31]	-8	hSpCas9	negative selection	11993442
68687524	68687547	16	-	28162770	MONOMAC1	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	0.5117973118237709	[144]	[236]	5	hSpCas9	negative selection	11993443
68687668	68687691	16	-	28162770	MONOMAC1	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-2.197036847059554	[51]	[12]	-9	hSpCas9	negative selection	11993444
68691828	68691851	16	-	28162770	OCIAML2	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	1.0257960008773375	[6]	[78]	8	hSpCas9	negative selection	12162804
68678130	68678153	16	+	28162770	OCIAML2	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	0.489140329969306	[49]	[388]	5	hSpCas9	negative selection	12162805
68678617	68678640	16	+	28162770	OCIAML2	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	1.616833016008178	[13]	[237]	9	hSpCas9	negative selection	12162806
68678859	68678882	16	+	28162770	OCIAML2	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	-0.1542612556966998	[103]	[517]	-1	hSpCas9	negative selection	12162807
68684761	68684784	16	-	28162770	OCIAML2	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-2.345098943158302	[21]	[23]	-8	hSpCas9	negative selection	12162808
68687524	68687547	16	-	28162770	OCIAML2	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	0.48517037084730374	[28]	[224]	5	hSpCas9	negative selection	12162809
68687668	68687691	16	-	28162770	OCIAML2	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-4.171069543383254	[12]	[3]	-9	hSpCas9	negative selection	12162810
68691828	68691851	16	-	28162770	OCIAML3	viability	GCCATGGCAGTCGCACACAGTGG	CDH3	ENSG00000062038	0.4209427011418081	[23]	[96]	4	hSpCas9	negative selection	12332170
68678130	68678153	16	+	28162770	OCIAML3	viability	GCAGGAAAGAAGGTCACTGAAGG	CDH3	ENSG00000062038	0.6381658018048703	[62]	[295]	6	hSpCas9	negative selection	12332171
68678617	68678640	16	+	28162770	OCIAML3	viability	GAATAAGCCACTGGACCGGGAGG	CDH3	ENSG00000062038	-1.5450980398432168	[28]	[29]	-8	hSpCas9	negative selection	12332172
68678859	68678882	16	+	28162770	OCIAML3	viability	TTACCCAGGACACCTTCCGAGGG	CDH3	ENSG00000062038	0.019524012593763906	[149]	[458]	0	hSpCas9	negative selection	12332173
68684761	68684784	16	-	28162770	OCIAML3	viability	GACACACACAGGCTCCCCAGTGG	CDH3	ENSG00000062038	-0.9071655255837936	[40]	[65]	-6	hSpCas9	negative selection	12332174
68687524	68687547	16	-	28162770	OCIAML3	viability	CAGAAGGGTTCCCGTGCCAGTGG	CDH3	ENSG00000062038	0.45038647903429035	[55]	[230]	4	hSpCas9	negative selection	12332175
68687668	68687691	16	-	28162770	OCIAML3	viability	GAGCTGGGCCTGGAAAGGGGAGG	CDH3	ENSG00000062038	-1.5940076403241634	[24]	[24]	-8	hSpCas9	negative selection	12332176