Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 386593
• Symbol: CHKB-CPT1B
• Description: CHKB-CPT1B readthrough (NMD candidate)

DataSource: http://genomecrispr.dkfz.de/#!/results/CHKB-CPT1B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
50578176	50578199	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGAAGGGCAGCCTGGAGTTGG	CHKB-CPT1B	ENSG00000254413	0.00034660392925700556	[321,131]	[22,77]	0	dCas9-VP64	positive selection	2402275
50578238	50578261	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCCAGGCCGGCTCCACTTCCAGG	CHKB-CPT1B	ENSG00000254413	0.7005676686591082	[529,57]	[196,2]	3	dCas9-VP64	positive selection	2402276
50578148	50578171	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGGCTCCTGGAGCTTTCAAGG	CHKB-CPT1B	ENSG00000254413	1.8622312284896627	[61,80]	[85,25]	6	dCas9-VP64	positive selection	2402277
50578618	50578641	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACGAGACTCTGGGGCCCCCCAGG	CHKB-CPT1B	ENSG00000254413	0.8556567606917811	[67,11]	[27,2]	3	dCas9-VP64	positive selection	2435556
50578587	50578610	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCGGTGAAGGTTGCTCAAAGG	CHKB-CPT1B	ENSG00000254413	2.5553754638539186	[124,165]	[78,307]	8	dCas9-VP64	positive selection	2435557
50578558	50578581	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGAATTGCAGGGCGCGGCTGG	CHKB-CPT1B	ENSG00000254413	1.7101786435317228	[134,312]	[128,198]	6	dCas9-VP64	positive selection	2435558
50578743	50578766	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATGAAGACGACCCTGAGGTGGGG	CHKB-CPT1B	ENSG00000254413	1.2212369388516109	[220,90]	[123,30]	5	dCas9-VP64	positive selection	2466666
50578767	50578790	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGAGGAGGAGAGTGATGGGGG	CHKB-CPT1B	ENSG00000254413	2.568343794012122	[9,39]	[44,20]	8	dCas9-VP64	positive selection	2466667
50578803	50578826	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	TATTATTCTAAGCTGCAGCCAGG	CHKB-CPT1B	ENSG00000254413	-1.3600920173469275	[418,748]	[35,64]	-7	dCas9-VP64	positive selection	2466668
50578176	50578199	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGAAGGGCAGCCTGGAGTTGG	CHKB-CPT1B	ENSG00000254413	-0.690850224305681	[184,127]	[31,30]	-6	dCas9-VP64	positive selection	2497530
50578238	50578261	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCCAGGCCGGCTCCACTTCCAGG	CHKB-CPT1B	ENSG00000254413	-1.2493502562546417	[102,139]	[18,12]	-9	dCas9-VP64	positive selection	2497531
50578148	50578171	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGGCTCCTGGAGCTTTCAAGG	CHKB-CPT1B	ENSG00000254413	4.913918421315813	[172,65]	[2451,17]	9	dCas9-VP64	positive selection	2497532
50578618	50578641	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACGAGACTCTGGGGCCCCCCAGG	CHKB-CPT1B	ENSG00000254413	0.025185322930492582	[53,53]	[21,13]	0	dCas9-VP64	positive selection	2530811
50578587	50578610	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCGGTGAAGGTTGCTCAAAGG	CHKB-CPT1B	ENSG00000254413	2.5174103154318317	[470,196]	[274,962]	9	dCas9-VP64	positive selection	2530812
50578558	50578581	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGAATTGCAGGGCGCGGCTGG	CHKB-CPT1B	ENSG00000254413	0.6507526082732698	[170,106]	[90,52]	5	dCas9-VP64	positive selection	2530813
50578743	50578766	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATGAAGACGACCCTGAGGTGGGG	CHKB-CPT1B	ENSG00000254413	0.5852029355498831	[862,284]	[234,329]	4	dCas9-VP64	positive selection	2561921
50578767	50578790	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGAGGAGGAGAGTGATGGGGG	CHKB-CPT1B	ENSG00000254413	0.8303596950132197	[104,217]	[44,137]	5	dCas9-VP64	positive selection	2561922
50578803	50578826	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	TATTATTCTAAGCTGCAGCCAGG	CHKB-CPT1B	ENSG00000254413	-0.16886135249065815	[737,509]	[145,214]	-2	dCas9-VP64	positive selection	2561923
50577764	50577787	22	-	27013184	SW480	treatment with recombinant TRAIL	ATCCGCATCAAGGTGCGCACAGG	CHKB-CPT1B	ENSG00000254413	-0.39413907227928097	[151,331]	[68,87]	-2	hSpCas9	positive selection	2967616
50577774	50577797	22	-	27013184	SW480	treatment with recombinant TRAIL	GAAACGCCTGATCCGCATCAAGG	CHKB-CPT1B	ENSG00000254413	1.6987081412142344	[89,111]	[168,98]	7	hSpCas9	positive selection	2967617
50577799	50577822	22	-	27013184	SW480	treatment with recombinant TRAIL	ACCTGTCTGGGATCAACTCCTGG	CHKB-CPT1B	ENSG00000254413	0.5261460740518309	[596,490]	[217,515]	2	hSpCas9	positive selection	2967618
50577811	50577834	22	-	27013184	SW480	treatment with recombinant TRAIL	TGAAACACGTCTACCTGTCTGGG	CHKB-CPT1B	ENSG00000254413	-0.36714654599529684	[134,221]	[50,68]	-2	hSpCas9	positive selection	2967620
50577812	50577835	22	-	27013184	SW480	treatment with recombinant TRAIL	CTGAAACACGTCTACCTGTCTGG	CHKB-CPT1B	ENSG00000254413	1.1812259751763103	[209,271]	[221,248]	5	hSpCas9	positive selection	2967621
50577837	50577860	22	-	27013184	SW480	treatment with recombinant TRAIL	CGACTTCCGGCTCAGTCGGGAGG	CHKB-CPT1B	ENSG00000254413	-1.2358844932113633	[99,40]	[19,3]	-5	hSpCas9	positive selection	2967622
50577850	50577873	22	-	27013184	SW480	treatment with recombinant TRAIL	CCCCAGACGGGGTCGACTTCCGG	CHKB-CPT1B	ENSG00000254413	0.3149285860593821	[122,64]	[43,62]	1	hSpCas9	positive selection	2967623
50577861	50577884	22	-	27013184	SW480	treatment with recombinant TRAIL	GTTCACGGTGACCCCAGACGGGG	CHKB-CPT1B	ENSG00000254413	1.878203795018977	[233,313]	[518,300]	8	hSpCas9	positive selection	2967625
50577862	50577885	22	-	27013184	SW480	treatment with recombinant TRAIL	AGTTCACGGTGACCCCAGACGGG	CHKB-CPT1B	ENSG00000254413	1.9071481732582916	[174,259]	[432,221]	8	hSpCas9	positive selection	2967627
50577863	50577886	22	-	27013184	SW480	treatment with recombinant TRAIL	CAGTTCACGGTGACCCCAGACGG	CHKB-CPT1B	ENSG00000254413	0.4108418291519378	[18,55]	[1,46]	2	hSpCas9	positive selection	2967628
50577798	50577821	22	+	27013184	SW480	treatment with recombinant TRAIL	TCCAGGAGTTGATCCCAGACAGG	CHKB-CPT1B	ENSG00000254413	-2.3639456091962447	[165,55]	[5,14]	-8	hSpCas9	positive selection	2967635
50577813	50577836	22	+	27013184	SW480	treatment with recombinant TRAIL	CAGACAGGTAGACGTGTTTCAGG	CHKB-CPT1B	ENSG00000254413	1.0230350632217524	[196,279]	[188,229]	5	hSpCas9	positive selection	2967637
50577814	50577837	22	+	27013184	SW480	treatment with recombinant TRAIL	AGACAGGTAGACGTGTTTCAGGG	CHKB-CPT1B	ENSG00000254413	0.12123990980134153	[208,282]	[122,100]	0	hSpCas9	positive selection	2967638
50577831	50577854	22	+	27013184	SW480	treatment with recombinant TRAIL	TCAGGGCCTCCCGACTGAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.25826116812695743	[103,193]	[15,103]	-1	hSpCas9	positive selection	2967639
50577848	50577871	22	+	27013184	SW480	treatment with recombinant TRAIL	AGCCGGAAGTCGACCCCGTCTGG	CHKB-CPT1B	ENSG00000254413	-0.08241929731843123	[557,549]	[201,259]	0	hSpCas9	positive selection	2967640
50577849	50577872	22	+	27013184	SW480	treatment with recombinant TRAIL	GCCGGAAGTCGACCCCGTCTGGG	CHKB-CPT1B	ENSG00000254413	-0.7778251289593098	[320,334]	[62,109]	-4	hSpCas9	positive selection	2967641
50577850	50577873	22	+	27013184	SW480	treatment with recombinant TRAIL	CCGGAAGTCGACCCCGTCTGGGG	CHKB-CPT1B	ENSG00000254413	0.10464703951070531	[303,547]	[171,221]	0	hSpCas9	positive selection	2967642
50577864	50577887	22	+	27013184	SW480	treatment with recombinant TRAIL	CGTCTGGGGTCACCGTGAACTGG	CHKB-CPT1B	ENSG00000254413	0.7692063091345458	[182,153]	[102,155]	4	hSpCas9	positive selection	2967643
50577868	50577891	22	+	27013184	SW480	treatment with recombinant TRAIL	TGGGGTCACCGTGAACTGGAAGG	CHKB-CPT1B	ENSG00000254413	1.6908678406907576	[226,691]	[792,352]	7	hSpCas9	positive selection	2967644
50577879	50577902	22	+	27013184	SW480	treatment with recombinant TRAIL	TGAACTGGAAGGCCACGGCCTGG	CHKB-CPT1B	ENSG00000254413	0.6770453721048576	[206,133]	[97,150]	3	hSpCas9	positive selection	2967645
50577361	50577384	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGCAACGTGGACATCTCCTTGG	CHKB-CPT1B	ENSG00000254413	0.3070909113332726	[6]	[5,6]	7	hSpCas9	positive selection	4129465
50577344	50577367	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATGCAACTGACCAGCCCCAAGG	CHKB-CPT1B	ENSG00000254413	0.2663693898024861	[5]	[5,3]	6	hSpCas9	positive selection	4129466
50576956	50576979	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	-0.28084409286328416	[3]	[1,1]	-6	hSpCas9	positive selection	4129467
50577361	50577384	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGCAACGTGGACATCTCCTTGG	CHKB-CPT1B	ENSG00000254413	0.9610162436702184	[7]	[7,6,6,5]	6	hSpCas9	positive selection	4193487
50577344	50577367	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATGCAACTGACCAGCCCCAAGG	CHKB-CPT1B	ENSG00000254413	0.17323437333880579	[4]	[3,1,4,0]	1	hSpCas9	positive selection	4193488
50576956	50576979	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.3476990605712416	[3]	[0,3,4,0]	2	hSpCas9	positive selection	4193489
50576611	50576634	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.5108101857588505	[2]	[2,3]	9	hSpCas9	positive selection	4264717
50576284	50576307	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	0.0021661441920191593	[2]	[3,0]	0	hSpCas9	positive selection	4264718
50576527	50576550	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.07049593071162175	[1]	[2,0]	1	hSpCas9	positive selection	4264719
50576956	50576979	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.2520168262947932	[1]	[2,0]	5	hSpCas9	positive selection	4328987
50577404	50577427	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.06603098802606086	[3]	[2,2]	-1	hSpCas9	positive selection	4328988
50576308	50576331	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.17340901229913985	[3]	[2,1]	-3	hSpCas9	positive selection	4328989
50576611	50576634	22	-	27260156	BXPC3	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.04682455498550858	[364]	[324,425,422,407]	1	hSpCas9	negative selection	5537177
50576284	50576307	22	-	27260156	BXPC3	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.13310438482611514	[375]	[362,296,413,361]	-3	hSpCas9	negative selection	5537178
50576527	50576550	22	+	27260156	BXPC3	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.4145883590067929	[123]	[157,150,208,175]	8	hSpCas9	negative selection	5537179
50576956	50576979	22	+	27260156	BXPC3	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.2738845869375066	[121]	[175,192,134,99]	6	hSpCas9	negative selection	5601447
50577404	50577427	22	+	27260156	BXPC3	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.07363898079093284	[677]	[646,612,630,822]	-2	hSpCas9	negative selection	5601448
50576308	50576331	22	-	27260156	BXPC3	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.22002162157303054	[558]	[474,347,613,591]	-5	hSpCas9	negative selection	5601449
50576611	50576634	22	-	27260156	A673	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.04446784345748578	[364]	[554,360,347,453]	-1	hSpCas9	negative selection	5658428
50576284	50576307	22	-	27260156	A673	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.3715552962820756	[375]	[340,401,217,437]	-7	hSpCas9	negative selection	5658429
50576527	50576550	22	+	27260156	A673	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.7617816751304851	[123]	[275,251,278,201]	9	hSpCas9	negative selection	5658430
50576956	50576979	22	+	27260156	A673	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	-0.01861591791662498	[121]	[120,167,138,146]	0	hSpCas9	negative selection	5722698
50577404	50577427	22	+	27260156	A673	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	0.03453773378289027	[677]	[946,737,847,814]	0	hSpCas9	negative selection	5722699
50576308	50576331	22	-	27260156	A673	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.3318854404954323	[558]	[564,466,601,500]	-7	hSpCas9	negative selection	5722700
50576611	50576634	22	-	27260156	A375	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.372608043903835	[364]	[455,794,502,491]	5	hSpCas9	negative selection	5779679
50576284	50576307	22	-	27260156	A375	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	0.2298803745281429	[375]	[523,504,514,512]	3	hSpCas9	negative selection	5779680
50576527	50576550	22	+	27260156	A375	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.5086622998496415	[123]	[216,204,71,315]	7	hSpCas9	negative selection	5779681
50576956	50576979	22	+	27260156	A375	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.027966907517821937	[121]	[296,111,86,87]	0	hSpCas9	negative selection	5843949
50577404	50577427	22	+	27260156	A375	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	0.22209496811315832	[677]	[1015,1119,602,973]	3	hSpCas9	negative selection	5843950
50576308	50576331	22	-	27260156	A375	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.30877469079316294	[558]	[543,527,704,350]	-4	hSpCas9	negative selection	5843951
50576611	50576634	22	-	27260156	COLO741	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.13723096078932617	[364]	[447,356,464]	-3	hSpCas9	negative selection	5900930
50576284	50576307	22	-	27260156	COLO741	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	0.0017855822323380455	[375]	[395,544,492]	0	hSpCas9	negative selection	5900931
50576527	50576550	22	+	27260156	COLO741	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.4022979584220463	[123]	[222,170,232]	7	hSpCas9	negative selection	5900932
50576956	50576979	22	+	27260156	COLO741	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.6540844336104656	[121]	[290,242,207]	9	hSpCas9	negative selection	5965200
50577404	50577427	22	+	27260156	COLO741	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.0682725053285107	[677]	[849,762,862]	-1	hSpCas9	negative selection	5965201
50576308	50576331	22	-	27260156	COLO741	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.7179342642417711	[558]	[672,346,310]	-9	hSpCas9	negative selection	5965202
50576611	50576634	22	-	27260156	CAL120	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.1324579955399231	[364]	[572,504,427]	2	hSpCas9	negative selection	6022181
50576284	50576307	22	-	27260156	CAL120	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.3977769209397821	[375]	[263,400,385]	-5	hSpCas9	negative selection	6022182
50576527	50576550	22	+	27260156	CAL120	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.5162018641544679	[123]	[220,219,220]	7	hSpCas9	negative selection	6022183
50576956	50576979	22	+	27260156	CAL120	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.29797590487036274	[121]	[220,155,187]	4	hSpCas9	negative selection	6086451
50577404	50577427	22	+	27260156	CAL120	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.14532049167984623	[677]	[863,818,622]	-2	hSpCas9	negative selection	6086452
50576308	50576331	22	-	27260156	CAL120	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	0.25242743495685926	[558]	[728,1106,637]	4	hSpCas9	negative selection	6086453
50576611	50576634	22	-	27260156	CADOES1	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.18835464337314345	[364]	[261,288,310,330]	-3	hSpCas9	negative selection	6143432
50576284	50576307	22	-	27260156	CADOES1	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.08742687675227967	[375]	[171,438,355,350]	-1	hSpCas9	negative selection	6143433
50576527	50576550	22	+	27260156	CADOES1	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.2515916212031706	[123]	[159,144,110,132]	4	hSpCas9	negative selection	6143434
50576956	50576979	22	+	27260156	CADOES1	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.8453191378930389	[121]	[220,278,151,161]	9	hSpCas9	negative selection	6207702
50577404	50577427	22	+	27260156	CADOES1	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.006762821600264313	[677]	[622,761,646,472]	0	hSpCas9	negative selection	6207703
50576308	50576331	22	-	27260156	CADOES1	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.8690149664474933	[558]	[367,245,273,248]	-9	hSpCas9	negative selection	6207704
50576611	50576634	22	-	27260156	EWS502	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.07530832522236425	[364]	[446,331,349,502]	1	hSpCas9	negative selection	6264683
50576284	50576307	22	-	27260156	EWS502	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.3111604776825444	[375]	[229,417,220,426]	-5	hSpCas9	negative selection	6264684
50576527	50576550	22	+	27260156	EWS502	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.5618534415371343	[123]	[161,181,173,265]	8	hSpCas9	negative selection	6264685
50576956	50576979	22	+	27260156	EWS502	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.01071485451670573	[121]	[62,176,137,149]	0	hSpCas9	negative selection	6328953
50577404	50577427	22	+	27260156	EWS502	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	0.07351538977058569	[677]	[693,731,854,747]	1	hSpCas9	negative selection	6328954
50576308	50576331	22	-	27260156	EWS502	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.2763566290137116	[558]	[494,459,482,517]	-5	hSpCas9	negative selection	6328955
50576611	50576634	22	-	27260156	EW8	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.11625885855164236	[364]	[306,233,244,312]	-2	hSpCas9	negative selection	6385934
50576284	50576307	22	-	27260156	EW8	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.45184191074009483	[375]	[249,307,145,202]	-7	hSpCas9	negative selection	6385935
50576527	50576550	22	+	27260156	EW8	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.6203518457930193	[123]	[114,163,190,136]	9	hSpCas9	negative selection	6385936
50576956	50576979	22	+	27260156	EW8	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	-0.05633722800925911	[121]	[116,88,97,77]	-1	hSpCas9	negative selection	6450204
50577404	50577427	22	+	27260156	EW8	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.21786980375628456	[677]	[523,390,523,445]	-4	hSpCas9	negative selection	6450205
50576308	50576331	22	-	27260156	EW8	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.3235297781300435	[558]	[430,366,192,491]	-6	hSpCas9	negative selection	6450206
50576611	50576634	22	-	27260156	CORL105	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.39509792647619457	[364]	[561,583,554,544]	7	hSpCas9	negative selection	6507185
50576284	50576307	22	-	27260156	CORL105	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	0.2337782513981914	[375]	[515,486,575,500]	4	hSpCas9	negative selection	6507186
50576527	50576550	22	+	27260156	CORL105	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.7520282537705532	[123]	[278,192,300,215]	9	hSpCas9	negative selection	6507187
50576956	50576979	22	+	27260156	CORL105	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.2788909934563315	[121]	[167,101,160,260]	5	hSpCas9	negative selection	6571455
50577404	50577427	22	+	27260156	CORL105	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.09617606006299229	[677]	[962,800,720,488]	-2	hSpCas9	negative selection	6571456
50576308	50576331	22	-	27260156	CORL105	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.528300595029219	[558]	[441,431,467,474]	-7	hSpCas9	negative selection	6571457
50576611	50576634	22	-	27260156	HS294T	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.10079933780750044	[364]	[135,241,74,149]	1	hSpCas9	negative selection	6628436
50576284	50576307	22	-	27260156	HS294T	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.066172511003528	[375]	[129,110,130,193]	-1	hSpCas9	negative selection	6628437
50576527	50576550	22	+	27260156	HS294T	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.26565562353994365	[123]	[71,33,49,76]	3	hSpCas9	negative selection	6628438
50576956	50576979	22	+	27260156	HS294T	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.08333828480744421	[121]	[27,36,68,71]	1	hSpCas9	negative selection	6692706
50577404	50577427	22	+	27260156	HS294T	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.18523396179815332	[677]	[241,271,193,206]	-3	hSpCas9	negative selection	6692707
50576308	50576331	22	-	27260156	HS294T	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.23606801845948078	[558]	[158,88,297,194]	-3	hSpCas9	negative selection	6692708
50576611	50576634	22	-	27260156	HCC44	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.03319499202363457	[364]	[514,344,403,437]	0	hSpCas9	negative selection	6749687
50576284	50576307	22	-	27260156	HCC44	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.2887824317632648	[375]	[440,275,465,248]	-4	hSpCas9	negative selection	6749688
50576527	50576550	22	+	27260156	HCC44	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.318907699329698	[123]	[197,126,198,186]	5	hSpCas9	negative selection	6749689
50576956	50576979	22	+	27260156	HCC44	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	-0.005202876739252238	[121]	[253,12,106,195]	0	hSpCas9	negative selection	6813957
50577404	50577427	22	+	27260156	HCC44	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	0.3774334108065306	[677]	[1471,718,763,1061]	6	hSpCas9	negative selection	6813958
50576308	50576331	22	-	27260156	HCC44	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.6263134766911207	[558]	[514,366,317,433]	-7	hSpCas9	negative selection	6813959
50576611	50576634	22	-	27260156	G402	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.13233610715230665	[364]	[1118,354,196,368]	1	hSpCas9	negative selection	6870938
50576284	50576307	22	-	27260156	G402	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.30940598377875694	[375]	[577,479,195,266]	-4	hSpCas9	negative selection	6870939
50576527	50576550	22	+	27260156	G402	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	-0.4770604419855069	[123]	[74,64,220,67]	-5	hSpCas9	negative selection	6870940
50576956	50576979	22	+	27260156	G402	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.14993108560446267	[121]	[295,148,46,184]	2	hSpCas9	negative selection	6935208
50577404	50577427	22	+	27260156	G402	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	0.6555724879149094	[677]	[1369,990,894,1912]	7	hSpCas9	negative selection	6935209
50576308	50576331	22	-	27260156	G402	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.9655184656816018	[558]	[384,355,387,275]	-8	hSpCas9	negative selection	6935210
50576611	50576634	22	-	27260156	L33	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.3297105845887219	[364]	[361,235,217,550]	7	hSpCas9	negative selection	6992189
50576284	50576307	22	-	27260156	L33	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.1030743825175453	[375]	[408,141,208,310]	-2	hSpCas9	negative selection	6992190
50576527	50576550	22	+	27260156	L33	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.7556672167622143	[123]	[247,74,139,182]	9	hSpCas9	negative selection	6992191
50576956	50576979	22	+	27260156	L33	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	-0.0570710888014192	[121]	[101,61,74,96]	-1	hSpCas9	negative selection	7056459
50577404	50577427	22	+	27260156	L33	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.15874657693276228	[677]	[637,274,331,590]	-4	hSpCas9	negative selection	7056460
50576308	50576331	22	-	27260156	L33	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.5330654081277185	[558]	[360,131,260,446]	-8	hSpCas9	negative selection	7056461
50576611	50576634	22	-	27260156	K562	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.34460736513610335	[364]	[624,225,367,429]	4	hSpCas9	negative selection	7113440
50576284	50576307	22	-	27260156	K562	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.6597493738759976	[375]	[215,137,364,130]	-6	hSpCas9	negative selection	7113441
50576527	50576550	22	+	27260156	K562	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.44943400679793966	[123]	[267,229,76,50]	6	hSpCas9	negative selection	7113442
50576956	50576979	22	+	27260156	K562	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.25920639964728087	[121]	[172,77,122,142]	3	hSpCas9	negative selection	7177710
50577404	50577427	22	+	27260156	K562	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.08916601117117362	[677]	[440,834,563,438]	-1	hSpCas9	negative selection	7177711
50576308	50576331	22	-	27260156	K562	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.20918205161083414	[558]	[346,537,619,231]	-3	hSpCas9	negative selection	7177712
50576611	50576634	22	-	27260156	HT29	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.0780883982443275	[364]	[511,545,342,308]	-2	hSpCas9	negative selection	7234691
50576284	50576307	22	-	27260156	HT29	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.09282875634891763	[375]	[497,432,366,419]	-2	hSpCas9	negative selection	7234692
50576527	50576550	22	+	27260156	HT29	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.2220263231681967	[123]	[226,122,234,122]	4	hSpCas9	negative selection	7234693
50576956	50576979	22	+	27260156	HT29	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.357277667635157	[121]	[245,201,162,156]	7	hSpCas9	negative selection	7298961
50577404	50577427	22	+	27260156	HT29	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	0.26873668588786515	[677]	[977,1071,934,985]	5	hSpCas9	negative selection	7298962
50576308	50576331	22	-	27260156	HT29	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.6199441418044749	[558]	[451,357,533,417]	-8	hSpCas9	negative selection	7298963
50576611	50576634	22	-	27260156	MHHES1	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.09866832431611039	[364]	[239,695,391,426]	1	hSpCas9	negative selection	7355942
50576284	50576307	22	-	27260156	MHHES1	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	0.10232370078454706	[375]	[561,358,637,291]	2	hSpCas9	negative selection	7355943
50576527	50576550	22	+	27260156	MHHES1	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.9329064991336746	[123]	[275,422,235,165]	9	hSpCas9	negative selection	7355944
50576956	50576979	22	+	27260156	MHHES1	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	-0.23307754098396583	[121]	[140,109,83,128]	-4	hSpCas9	negative selection	7420212
50577404	50577427	22	+	27260156	MHHES1	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.20526913795557822	[677]	[703,693,537,696]	-4	hSpCas9	negative selection	7420213
50576308	50576331	22	-	27260156	MHHES1	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.6569439260215928	[558]	[421,545,305,343]	-8	hSpCas9	negative selection	7420214
50576611	50576634	22	-	27260156	MEWO	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.14334614418102226	[364]	[290,516,305]	3	hSpCas9	negative selection	7477193
50576284	50576307	22	-	27260156	MEWO	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.28585449845066324	[375]	[387,253,242]	-6	hSpCas9	negative selection	7477194
50576527	50576550	22	+	27260156	MEWO	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.5033410634989126	[123]	[176,107,210]	8	hSpCas9	negative selection	7477195
50576956	50576979	22	+	27260156	MEWO	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	-0.5737833425550827	[121]	[85,43,101]	-8	hSpCas9	negative selection	7541463
50577404	50577427	22	+	27260156	MEWO	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.03724738900230301	[677]	[683,628,553]	-1	hSpCas9	negative selection	7541464
50576308	50576331	22	-	27260156	MEWO	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.5929640335827854	[558]	[474,335,253]	-8	hSpCas9	negative selection	7541465
50576611	50576634	22	-	27260156	LNCAPCLONEFGC	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.09848035823584617	[364]	[474,323,364,252]	1	hSpCas9	negative selection	7598444
50576284	50576307	22	-	27260156	LNCAPCLONEFGC	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.02044337066418539	[375]	[328,252,425,353]	0	hSpCas9	negative selection	7598445
50576527	50576550	22	+	27260156	LNCAPCLONEFGC	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.849418395236377	[123]	[227,181,139,250]	9	hSpCas9	negative selection	7598446
50576956	50576979	22	+	27260156	LNCAPCLONEFGC	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.3143347654868571	[121]	[115,178,155,98]	5	hSpCas9	negative selection	7662714
50577404	50577427	22	+	27260156	LNCAPCLONEFGC	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.05399319806059466	[677]	[535,624,753,473]	-1	hSpCas9	negative selection	7662715
50576308	50576331	22	-	27260156	LNCAPCLONEFGC	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.6443538235398578	[558]	[267,249,467,336]	-7	hSpCas9	negative selection	7662716
50576611	50576634	22	-	27260156	PANC0327	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.21436735638897697	[364]	[242,200,351,328]	-3	hSpCas9	negative selection	7719695
50576284	50576307	22	-	27260156	PANC0327	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	0.3333438583769711	[375]	[142,412,330,773]	5	hSpCas9	negative selection	7719696
50576527	50576550	22	+	27260156	PANC0327	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.8374869237463174	[123]	[58,279,109,315]	9	hSpCas9	negative selection	7719697
50576956	50576979	22	+	27260156	PANC0327	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.5931315632911498	[121]	[45,81,316,209]	8	hSpCas9	negative selection	7783965
50577404	50577427	22	+	27260156	PANC0327	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	0.05550431734232364	[677]	[534,432,777,774]	0	hSpCas9	negative selection	7783966
50576308	50576331	22	-	27260156	PANC0327	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.49320748554486576	[558]	[351,336,361,361]	-6	hSpCas9	negative selection	7783967
50576611	50576634	22	-	27260156	NCIH2009	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.12808373281104835	[364]	[723,442,538]	1	hSpCas9	negative selection	7840946
50576284	50576307	22	-	27260156	NCIH2009	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.513245441883732	[375]	[634,276,245]	-6	hSpCas9	negative selection	7840947
50576527	50576550	22	+	27260156	NCIH2009	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	1.3972443877428744	[123]	[400,636,315]	9	hSpCas9	negative selection	7840948
50576956	50576979	22	+	27260156	NCIH2009	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.6587813777695848	[121]	[490,142,218]	8	hSpCas9	negative selection	7905216
50577404	50577427	22	+	27260156	NCIH2009	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.3120804719075919	[677]	[753,649,883]	-4	hSpCas9	negative selection	7905217
50576308	50576331	22	-	27260156	NCIH2009	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.5285902673198486	[558]	[733,563,362]	-6	hSpCas9	negative selection	7905218
50576611	50576634	22	-	27260156	NCIH1373	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.27032265190104776	[364]	[319,386,492,202]	2	hSpCas9	negative selection	7962197
50576284	50576307	22	-	27260156	NCIH1373	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.06265601132866766	[375]	[535,572,219,73]	0	hSpCas9	negative selection	7962198
50576527	50576550	22	+	27260156	NCIH1373	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.7645994045457072	[123]	[260,132,413,36]	7	hSpCas9	negative selection	7962199
50576956	50576979	22	+	27260156	NCIH1373	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.23855343262313022	[121]	[215,62,226,40]	2	hSpCas9	negative selection	8026467
50577404	50577427	22	+	27260156	NCIH1373	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	0.017188391859564445	[677]	[552,859,648,257]	0	hSpCas9	negative selection	8026468
50576308	50576331	22	-	27260156	NCIH1373	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.7933691865196029	[558]	[577,178,441,76]	-7	hSpCas9	negative selection	8026469
50576611	50576634	22	-	27260156	PATU8902	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.3165214627409316	[364]	[800,545,624,543]	3	hSpCas9	negative selection	8083448
50576284	50576307	22	-	27260156	PATU8902	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	0.7840833945788721	[375]	[672,925,692,1427]	8	hSpCas9	negative selection	8083449
50576527	50576550	22	+	27260156	PATU8902	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.307244510995897	[123]	[229,221,132,298]	3	hSpCas9	negative selection	8083450
50576956	50576979	22	+	27260156	PATU8902	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.25648814414797294	[121]	[167,165,105,421]	2	hSpCas9	negative selection	8147718
50577404	50577427	22	+	27260156	PATU8902	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	0.36090060950856884	[677]	[1360,1399,804,1401]	3	hSpCas9	negative selection	8147719
50576308	50576331	22	-	27260156	PATU8902	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.6354313773197025	[558]	[516,717,528,192]	-6	hSpCas9	negative selection	8147720
50576611	50576634	22	-	27260156	PANC1	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.09837340656286059	[364]	[241,290,423,367]	1	hSpCas9	negative selection	8204699
50576284	50576307	22	-	27260156	PANC1	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.0979162744265556	[375]	[355,251,284,297]	-2	hSpCas9	negative selection	8204700
50576527	50576550	22	+	27260156	PANC1	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.5939180492655367	[123]	[275,153,160,61]	8	hSpCas9	negative selection	8204701
50576956	50576979	22	+	27260156	PANC1	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.3858672621090484	[121]	[117,145,141,140]	6	hSpCas9	negative selection	8268969
50577404	50577427	22	+	27260156	PANC1	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.2602560120533892	[677]	[349,588,461,548]	-4	hSpCas9	negative selection	8268970
50576308	50576331	22	-	27260156	PANC1	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.7506257413236059	[558]	[249,422,364,150]	-8	hSpCas9	negative selection	8268971
50576611	50576634	22	-	27260156	PANC0813	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.2716718480233204	[364]	[655,544,422,460]	4	hSpCas9	negative selection	8325950
50576284	50576307	22	-	27260156	PANC0813	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	0.3287186130812661	[375]	[453,470,756,528]	5	hSpCas9	negative selection	8325951
50576527	50576550	22	+	27260156	PANC0813	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.4851616653997941	[123]	[178,190,220,220]	7	hSpCas9	negative selection	8325952
50576956	50576979	22	+	27260156	PANC0813	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.21420211040401438	[121]	[191,211,169,96]	3	hSpCas9	negative selection	8390220
50577404	50577427	22	+	27260156	PANC0813	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.12365514060806826	[677]	[756,842,757,575]	-2	hSpCas9	negative selection	8390221
50576308	50576331	22	-	27260156	PANC0813	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.29291561775016356	[558]	[637,434,465,608]	-4	hSpCas9	negative selection	8390222
50576611	50576634	22	-	27260156	RDES	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.08460275673458811	[364]	[302,450,481,584]	1	hSpCas9	negative selection	8447201
50576284	50576307	22	-	27260156	RDES	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.2494053512249902	[375]	[366,234,301,581]	-4	hSpCas9	negative selection	8447202
50576527	50576550	22	+	27260156	RDES	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.7430733474225422	[123]	[133,154,382,326]	9	hSpCas9	negative selection	8447203
50576956	50576979	22	+	27260156	RDES	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.40750766987243314	[121]	[205,150,142,243]	6	hSpCas9	negative selection	8511471
50577404	50577427	22	+	27260156	RDES	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.012903087125678114	[677]	[683,588,918,943]	0	hSpCas9	negative selection	8511472
50576308	50576331	22	-	27260156	RDES	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.6368215074429562	[558]	[365,338,436,535]	-8	hSpCas9	negative selection	8511473
50576611	50576634	22	-	27260156	PC3	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.03988961262260554	[364]	[147,493,574,340]	-1	hSpCas9	negative selection	8568452
50576284	50576307	22	-	27260156	PC3	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.25092989606888416	[375]	[187,336,432,374]	-5	hSpCas9	negative selection	8568453
50576527	50576550	22	+	27260156	PC3	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.2336685747886027	[123]	[152,115,214,97]	5	hSpCas9	negative selection	8568454
50576956	50576979	22	+	27260156	PC3	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	-0.004193750610441915	[121]	[94,86,261,93]	0	hSpCas9	negative selection	8632722
50577404	50577427	22	+	27260156	PC3	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.018314837173657894	[677]	[443,800,992,573]	0	hSpCas9	negative selection	8632723
50576308	50576331	22	-	27260156	PC3	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.3578505847569659	[558]	[253,302,1033,429]	-7	hSpCas9	negative selection	8632724
50576611	50576634	22	-	27260156	PATU8988T	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.6205360744886137	[364]	[399,571,402,820]	8	hSpCas9	negative selection	8689703
50576284	50576307	22	-	27260156	PATU8988T	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	0.08830597260919879	[375]	[277,610,216,468]	1	hSpCas9	negative selection	8689704
50576527	50576550	22	+	27260156	PATU8988T	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	1.1721193244986057	[123]	[175,283,517,84]	9	hSpCas9	negative selection	8689705
50576956	50576979	22	+	27260156	PATU8988T	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.6273565353418944	[121]	[165,216,272,64]	8	hSpCas9	negative selection	8753973
50577404	50577427	22	+	27260156	PATU8988T	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.07448692242275634	[677]	[447,836,552,675]	-1	hSpCas9	negative selection	8753974
50576308	50576331	22	-	27260156	PATU8988T	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.6080004867298845	[558]	[354,268,434,348]	-7	hSpCas9	negative selection	8753975
50576611	50576634	22	-	27260156	T47D	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.00460607667073365	[364]	[438,363,448,448]	0	hSpCas9	negative selection	8810954
50576284	50576307	22	-	27260156	T47D	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.14620418869645385	[375]	[352,367,431,432]	-3	hSpCas9	negative selection	8810955
50576527	50576550	22	+	27260156	T47D	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.5608731027723111	[123]	[224,192,201,234]	9	hSpCas9	negative selection	8810956
50576956	50576979	22	+	27260156	T47D	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.0959479438678037	[121]	[160,101,180,167]	2	hSpCas9	negative selection	8875224
50577404	50577427	22	+	27260156	T47D	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	0.02892155228117832	[677]	[805,671,959,793]	0	hSpCas9	negative selection	8875225
50576308	50576331	22	-	27260156	T47D	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.29861200765892937	[558]	[545,556,525,484]	-6	hSpCas9	negative selection	8875226
50576611	50576634	22	-	27260156	SU8686	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	0.38296289902385483	[364]	[379,420,555,560]	6	hSpCas9	negative selection	8932205
50576284	50576307	22	-	27260156	SU8686	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	0.3986946358378173	[375]	[329,291,606,836]	6	hSpCas9	negative selection	8932206
50576527	50576550	22	+	27260156	SU8686	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.8526282181225544	[123]	[189,201,206,306]	9	hSpCas9	negative selection	8932207
50576956	50576979	22	+	27260156	SU8686	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.022035448352219822	[121]	[87,123,167,113]	0	hSpCas9	negative selection	8996475
50577404	50577427	22	+	27260156	SU8686	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.22313479873077513	[677]	[569,465,604,692]	-4	hSpCas9	negative selection	8996476
50576308	50576331	22	-	27260156	SU8686	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.2702851511041629	[558]	[450,371,598,422]	-4	hSpCas9	negative selection	8996477
50576611	50576634	22	-	27260156	SKES1	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.07653200294308865	[364]	[441,361,283,309]	-2	hSpCas9	negative selection	9053456
50576284	50576307	22	-	27260156	SKES1	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.18161447094395144	[375]	[324,295,383,310]	-4	hSpCas9	negative selection	9053457
50576527	50576550	22	+	27260156	SKES1	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.6073636836906067	[123]	[144,274,192,147]	9	hSpCas9	negative selection	9053458
50576956	50576979	22	+	27260156	SKES1	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.26229098557920905	[121]	[219,133,82,153]	5	hSpCas9	negative selection	9117726
50577404	50577427	22	+	27260156	SKES1	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.06481288843821831	[677]	[618,613,647,685]	-1	hSpCas9	negative selection	9117727
50576308	50576331	22	-	27260156	SKES1	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.4551331595377671	[558]	[486,431,383,341]	-7	hSpCas9	negative selection	9117728
50576611	50576634	22	-	27260156	TOV112D	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.02746003424649296	[364]	[403,315,514,196]	0	hSpCas9	negative selection	9174707
50576284	50576307	22	-	27260156	TOV112D	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.005781456637172222	[375]	[368,444,385,317]	0	hSpCas9	negative selection	9174708
50576527	50576550	22	+	27260156	TOV112D	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.696635556027684	[123]	[248,221,144,197]	9	hSpCas9	negative selection	9174709
50576956	50576979	22	+	27260156	TOV112D	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.33770080682249315	[121]	[121,168,126,198]	6	hSpCas9	negative selection	9238977
50577404	50577427	22	+	27260156	TOV112D	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.11581334867671905	[677]	[569,658,586,690]	-2	hSpCas9	negative selection	9238978
50576308	50576331	22	-	27260156	TOV112D	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.4073768166758535	[558]	[260,555,568,323]	-7	hSpCas9	negative selection	9238979
50576611	50576634	22	-	27260156	TC71	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.018015874243487495	[364]	[389,363,323,474]	0	hSpCas9	negative selection	9295958
50576284	50576307	22	-	27260156	TC71	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.1498819594390144	[375]	[415,295,370,368]	-4	hSpCas9	negative selection	9295959
50576527	50576550	22	+	27260156	TC71	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.39947321625269194	[123]	[129,180,174,218]	8	hSpCas9	negative selection	9295960
50576956	50576979	22	+	27260156	TC71	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.06455564234983568	[121]	[147,136,116,145]	1	hSpCas9	negative selection	9360228
50577404	50577427	22	+	27260156	TC71	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	-0.10896801781990806	[677]	[627,706,628,737]	-3	hSpCas9	negative selection	9360229
50576308	50576331	22	-	27260156	TC71	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.03638800910680892	[558]	[611,601,409,726]	-1	hSpCas9	negative selection	9360230
50576611	50576634	22	-	27260156	TC32	viability	GTATCCGCCTTCTATCCAGCCGG	CHKB-CPT1B	ENSG00000254413	-0.25611467937225074	[364]	[297,196,277,395]	-5	hSpCas9	negative selection	9417209
50576284	50576307	22	-	27260156	TC32	viability	TGATGAGGAATATTACCGCATGG	CHKB-CPT1B	ENSG00000254413	-0.24456376236928545	[375]	[246,241,322,400]	-4	hSpCas9	negative selection	9417210
50576527	50576550	22	+	27260156	TC32	viability	GGCCCTCACCCGCTGAATTGTGG	CHKB-CPT1B	ENSG00000254413	0.3538382484698417	[123]	[158,113,156,170]	6	hSpCas9	negative selection	9417211
50576956	50576979	22	+	27260156	TC32	viability	GCCCGTCACCCAGACGCCCGTGG	CHKB-CPT1B	ENSG00000254413	0.3143805346002826	[121]	[184,54,246,119]	5	hSpCas9	negative selection	9481479
50577404	50577427	22	+	27260156	TC32	viability	CATGATGACGACCAGCCAGCTGG	CHKB-CPT1B	ENSG00000254413	0.12202735247124807	[677]	[631,496,838,882]	2	hSpCas9	negative selection	9481480
50576308	50576331	22	-	27260156	TC32	viability	AGAGTCTGTGCGCCCCTTGTTGG	CHKB-CPT1B	ENSG00000254413	-0.5386771585369734	[558]	[412,331,357,320]	-8	hSpCas9	negative selection	9481481