Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 8029
• Symbol: Cubn
• Description: cubilin

DataSource: http://genomecrispr.dkfz.de/#!/results/Cubn

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
17110954	17110977	10	+	26472758	Jiyoye	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	-0.04573030336341355	[192]	[140]	0	hSpCas9	negative selection	38979
17084443	17084466	10	-	26472758	Jiyoye	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	-0.7592606338565591	[412]	[183]	-5	hSpCas9	negative selection	38980
16913885	16913908	10	-	26472758	Jiyoye	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	1.162062883669342	[95]	[161]	7	hSpCas9	negative selection	38981
16876963	16876986	10	+	26472758	Jiyoye	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	0.37742803811182135	[244]	[239]	3	hSpCas9	negative selection	38982
16869805	16869828	10	+	26472758	Jiyoye	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	0.9843605316353102	[123]	[184]	6	hSpCas9	negative selection	38983
17114157	17114180	10	-	26472758	Jiyoye	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	-0.22866828821746688	[100]	[64]	-2	hSpCas9	negative selection	38984
17110919	17110942	10	+	26472758	Jiyoye	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	1.6828098241193006	[18]	[45]	8	hSpCas9	negative selection	38985
17104497	17104520	10	+	26472758	Jiyoye	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	-0.02166791729800091	[139]	[103]	0	hSpCas9	negative selection	38986
17085710	17085733	10	+	26472758	Jiyoye	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	-0.4450337763359913	[342]	[189]	-3	hSpCas9	negative selection	38987
17085674	17085697	10	+	26472758	Jiyoye	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	-0.8389852057635243	[101]	[42]	-5	hSpCas9	negative selection	38988
17110954	17110977	10	+	26472758	KBM7	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.2277049880690358	[719,422]	[263,346]	2	hSpCas9	negative selection	230097
17084443	17084466	10	-	26472758	KBM7	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.1972739837480404	[1175,960]	[508,629]	2	hSpCas9	negative selection	230098
16913885	16913908	10	-	26472758	KBM7	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	0.4517075399339095	[333,180]	[163,158]	5	hSpCas9	negative selection	230099
16876963	16876986	10	+	26472758	KBM7	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	0.23143508237119725	[1131,900]	[607,511]	2	hSpCas9	negative selection	230100
16869805	16869828	10	+	26472758	KBM7	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	-0.2386382054463899	[580,681]	[274,236]	-2	hSpCas9	negative selection	230101
17114157	17114180	10	-	26472758	KBM7	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	1.0343989081307534	[168,212]	[167,203]	9	hSpCas9	negative selection	230102
17110919	17110942	10	+	26472758	KBM7	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	0.00427840927466927	[155,88]	[85,29]	0	hSpCas9	negative selection	230103
17104497	17104520	10	+	26472758	KBM7	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	0.32302606674299217	[740,761]	[542,356]	3	hSpCas9	negative selection	230104
17085710	17085733	10	+	26472758	KBM7	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.0524147246797646	[1222,1209]	[723,480]	0	hSpCas9	negative selection	230105
17085674	17085697	10	+	26472758	KBM7	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	-0.22131113637186983	[226,168]	[96,62]	-2	hSpCas9	negative selection	230106
17110954	17110977	10	+	26472758	Raji	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.6703197297647567	[175]	[64]	6	hSpCas9	negative selection	421215
17084443	17084466	10	-	26472758	Raji	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.293174942274933	[632]	[179]	2	hSpCas9	negative selection	421216
16913885	16913908	10	-	26472758	Raji	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	-0.38446956095607543	[179]	[31]	-3	hSpCas9	negative selection	421217
16876963	16876986	10	+	26472758	Raji	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	0.5689636205894735	[365]	[125]	5	hSpCas9	negative selection	421218
16869805	16869828	10	+	26472758	Raji	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	-0.40411680340653555	[267]	[46]	-3	hSpCas9	negative selection	421219
17114157	17114180	10	-	26472758	Raji	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	1.1073835353735995	[83]	[41]	8	hSpCas9	negative selection	421220
17110919	17110942	10	+	26472758	Raji	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	-0.6398503942464342	[46]	[6]	-5	hSpCas9	negative selection	421221
17104497	17104520	10	+	26472758	Raji	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	1.1477009905610878	[246]	[126]	8	hSpCas9	negative selection	421222
17085710	17085733	10	+	26472758	Raji	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.27011303541170784	[535]	[149]	2	hSpCas9	negative selection	421223
17085674	17085697	10	+	26472758	Raji	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	-0.5248846801259136	[123]	[19]	-4	hSpCas9	negative selection	421224
17110954	17110977	10	+	26472758	K562	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	-0.4366064948355384	[488]	[304]	-3	hSpCas9	negative selection	612333
17084443	17084466	10	-	26472758	K562	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.5891962829417774	[1114]	[1415]	5	hSpCas9	negative selection	612334
16913885	16913908	10	-	26472758	K562	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	0.36560507418650456	[193]	[210]	3	hSpCas9	negative selection	612335
16876963	16876986	10	+	26472758	K562	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	0.18862088923167963	[1027]	[988]	1	hSpCas9	negative selection	612336
16869805	16869828	10	+	26472758	K562	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	-0.030799332710921945	[546]	[451]	0	hSpCas9	negative selection	612337
17114157	17114180	10	-	26472758	K562	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	-0.008965508133627731	[148]	[124]	0	hSpCas9	negative selection	612338
17110919	17110942	10	+	26472758	K562	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	-0.8335837843348264	[94]	[44]	-5	hSpCas9	negative selection	612339
17104497	17104520	10	+	26472758	K562	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	-0.4361909002480907	[568]	[354]	-3	hSpCas9	negative selection	612340
17085710	17085733	10	+	26472758	K562	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	-0.42584777495739035	[1105]	[694]	-3	hSpCas9	negative selection	612341
17085674	17085697	10	+	26472758	K562	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	-0.11134296229679097	[150]	[117]	-1	hSpCas9	negative selection	612342
17105545	17105568	10	+	26627737	DLD1	viability	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	-0.12100250756820152	[2095]	[672,428,684]	-1	hSpCas9	negative selection	774519
17110900	17110923	10	+	26627737	DLD1	viability	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.30462611414246255	[458]	[220,220,102]	3	hSpCas9	negative selection	774520
17114077	17114100	10	+	26627737	DLD1	viability	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	-1.789532927138672	[527]	[33,27,75]	-8	hSpCas9	negative selection	774521
17115467	17115490	10	-	26627737	DLD1	viability	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-0.25070392933812646	[606]	[130,149,191]	-3	hSpCas9	negative selection	774522
17129227	17129250	10	-	26627737	DLD1	viability	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.5485094755506676	[489]	[190,382,120]	5	hSpCas9	negative selection	774523
17129689	17129712	10	-	26627737	DLD1	viability	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.1432087306957559	[181]	[38,124,31]	1	hSpCas9	negative selection	774524
17105545	17105568	10	+	26627737	GBM cells	viability after 5 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.3049370617079863	[882]	[631,537]	5	hSpCas9	negative selection	856834
17110900	17110923	10	+	26627737	GBM cells	viability after 5 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.22358734651186532	[209]	[176,85]	3	hSpCas9	negative selection	856835
17114077	17114100	10	+	26627737	GBM cells	viability after 5 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	-0.11402518082181265	[223]	[119,101]	-2	hSpCas9	negative selection	856836
17115467	17115490	10	-	26627737	GBM cells	viability after 5 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	0.38266412424854357	[245]	[191,151]	6	hSpCas9	negative selection	856837
17129227	17129250	10	-	26627737	GBM cells	viability after 5 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.2877674423608746	[277]	[226,136]	4	hSpCas9	negative selection	856838
17129689	17129712	10	-	26627737	GBM cells	viability after 5 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	1.0306195540975078	[67]	[91,56]	9	hSpCas9	negative selection	856839
17105545	17105568	10	+	26627737	GBM cells	viability after 13 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.21955552475627527	[882]	[671,464]	3	hSpCas9	negative selection	939149
17110900	17110923	10	+	26627737	GBM cells	viability after 13 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.3096642269287228	[209]	[95,177]	4	hSpCas9	negative selection	939150
17114077	17114100	10	+	26627737	GBM cells	viability after 13 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	-0.33400447622267104	[223]	[107,86]	-4	hSpCas9	negative selection	939151
17115467	17115490	10	-	26627737	GBM cells	viability after 13 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-0.05190036940773667	[245]	[125,130]	0	hSpCas9	negative selection	939152
17129227	17129250	10	-	26627737	GBM cells	viability after 13 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.4432629758913992	[277]	[246,170]	5	hSpCas9	negative selection	939153
17129689	17129712	10	-	26627737	GBM cells	viability after 13 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.6889230867123437	[67]	[48,67]	8	hSpCas9	negative selection	939154
17105545	17105568	10	+	26627737	GBM cells	viability after 21 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.44693891292833965	[882]	[690,619]	4	hSpCas9	negative selection	1021464
17110900	17110923	10	+	26627737	GBM cells	viability after 21 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	-0.5044899220076002	[209]	[93,67]	-4	hSpCas9	negative selection	1021465
17114077	17114100	10	+	26627737	GBM cells	viability after 21 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	-0.9379321438378667	[223]	[62,63]	-7	hSpCas9	negative selection	1021466
17115467	17115490	10	-	26627737	GBM cells	viability after 21 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	0.1560263897296577	[245]	[150,146]	1	hSpCas9	negative selection	1021467
17129227	17129250	10	-	26627737	GBM cells	viability after 21 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	-0.09836082725239212	[277]	[150,131]	-1	hSpCas9	negative selection	1021468
17129689	17129712	10	-	26627737	GBM cells	viability after 21 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.9575656737829937	[67]	[65,76]	8	hSpCas9	negative selection	1021469
17105545	17105568	10	+	26627737	RPE1	viability after 9 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.510805224572475	[2926]	[1447,1121]	3	hSpCas9	negative selection	1103779
17110900	17110923	10	+	26627737	RPE1	viability after 9 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.27030671222679825	[578]	[153,301]	2	hSpCas9	negative selection	1103780
17114077	17114100	10	+	26627737	RPE1	viability after 9 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	-0.4868343294365952	[512]	[73,166]	-3	hSpCas9	negative selection	1103781
17115467	17115490	10	-	26627737	RPE1	viability after 9 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-1.312535649326057	[1378]	[175,170]	-7	hSpCas9	negative selection	1103782
17129227	17129250	10	-	26627737	RPE1	viability after 9 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	1.2834498621746702	[577]	[429,453]	7	hSpCas9	negative selection	1103783
17129689	17129712	10	-	26627737	RPE1	viability after 9 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.17979398876282915	[409]	[123,172]	1	hSpCas9	negative selection	1103784
17105545	17105568	10	+	26627737	RPE1	viability after 12 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.30880929830985715	[2926]	[1010,934]	2	hSpCas9	negative selection	1186094
17110900	17110923	10	+	26627737	RPE1	viability after 12 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	-0.015592628759393434	[578]	[149,157]	0	hSpCas9	negative selection	1186095
17114077	17114100	10	+	26627737	RPE1	viability after 12 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	0.09549020098073702	[512]	[53,245]	0	hSpCas9	negative selection	1186096
17115467	17115490	10	-	26627737	RPE1	viability after 12 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-2.0451108814916124	[1378]	[64,115]	-8	hSpCas9	negative selection	1186097
17129227	17129250	10	-	26627737	RPE1	viability after 12 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	1.2945083143377407	[577]	[377,383]	7	hSpCas9	negative selection	1186098
17129689	17129712	10	-	26627737	RPE1	viability after 12 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	-0.21177854963701137	[409]	[81,108]	-1	hSpCas9	negative selection	1186099
17105545	17105568	10	+	26627737	RPE1	viability after 15 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.5847679016551688	[2926]	[1336,1149]	3	hSpCas9	negative selection	1268409
17110900	17110923	10	+	26627737	RPE1	viability after 15 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.4122591048510916	[578]	[191,242]	2	hSpCas9	negative selection	1268410
17114077	17114100	10	+	26627737	RPE1	viability after 15 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	-1.8377547960403189	[512]	[6,72]	-8	hSpCas9	negative selection	1268411
17115467	17115490	10	-	26627737	RPE1	viability after 15 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-1.958361042927401	[1378]	[50,147]	-8	hSpCas9	negative selection	1268412
17129227	17129250	10	-	26627737	RPE1	viability after 15 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.7148718958798606	[577]	[275,260]	4	hSpCas9	negative selection	1268413
17129689	17129712	10	-	26627737	RPE1	viability after 15 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	-0.11531889954655294	[409]	[74,137]	0	hSpCas9	negative selection	1268414
17105545	17105568	10	+	26627737	RPE1	viability after 18 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.9337295699210888	[2926]	[1694,1309]	5	hSpCas9	negative selection	1350724
17110900	17110923	10	+	26627737	RPE1	viability after 18 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.3841376963694568	[578]	[157,252]	2	hSpCas9	negative selection	1350725
17114077	17114100	10	+	26627737	RPE1	viability after 18 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	-1.223567103114402	[512]	[52,65]	-6	hSpCas9	negative selection	1350726
17115467	17115490	10	-	26627737	RPE1	viability after 18 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-2.340670932881552	[1378]	[57,89]	-8	hSpCas9	negative selection	1350727
17129227	17129250	10	-	26627737	RPE1	viability after 18 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	1.0642884732631646	[577]	[214,444]	6	hSpCas9	negative selection	1350728
17129689	17129712	10	-	26627737	RPE1	viability after 18 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.2478326957090884	[409]	[127,134]	1	hSpCas9	negative selection	1350729
17105545	17105568	10	+	26627737	HeLa	viability after 8 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	1.1087827534195909	[995]	[1186,877,803]	8	hSpCas9	negative selection	1433039
17110900	17110923	10	+	26627737	HeLa	viability after 8 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	-0.8431472923075961	[494]	[326,6,74]	-7	hSpCas9	negative selection	1433040
17114077	17114100	10	+	26627737	HeLa	viability after 8 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	-0.3576575791379788	[349]	[50,191,99]	-3	hSpCas9	negative selection	1433041
17115467	17115490	10	-	26627737	HeLa	viability after 8 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-0.3390502202576742	[567]	[232,188,173]	-3	hSpCas9	negative selection	1433042
17129227	17129250	10	-	26627737	HeLa	viability after 8 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.35242292067623493	[501]	[429,206,235]	3	hSpCas9	negative selection	1433043
17129689	17129712	10	-	26627737	HeLa	viability after 8 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	-0.37277713366062704	[332]	[138,139,65]	-4	hSpCas9	negative selection	1433044
17105545	17105568	10	+	26627737	HeLa	viability after 12 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.6883191237791126	[995]	[555,584,853]	5	hSpCas9	negative selection	1515354
17110900	17110923	10	+	26627737	HeLa	viability after 12 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	-0.7413933389577212	[494]	[239,79,54]	-6	hSpCas9	negative selection	1515355
17114077	17114100	10	+	26627737	HeLa	viability after 12 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	-0.14351400908354528	[349]	[165,72,160]	-1	hSpCas9	negative selection	1515356
17115467	17115490	10	-	26627737	HeLa	viability after 12 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-0.28755133318228393	[567]	[132,184,257]	-3	hSpCas9	negative selection	1515357
17129227	17129250	10	-	26627737	HeLa	viability after 12 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.32718038112464143	[501]	[268,241,271]	3	hSpCas9	negative selection	1515358
17129689	17129712	10	-	26627737	HeLa	viability after 12 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	-0.8976249054539037	[332]	[101,58,62]	-7	hSpCas9	negative selection	1515359
17105545	17105568	10	+	26627737	HeLa	viability after 15 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.5844812337007623	[995]	[461,778,582]	5	hSpCas9	negative selection	1597669
17110900	17110923	10	+	26627737	HeLa	viability after 15 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	-0.6542666100278403	[494]	[300,11,63]	-5	hSpCas9	negative selection	1597670
17114077	17114100	10	+	26627737	HeLa	viability after 15 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	-0.016001002171357054	[349]	[178,44,202]	0	hSpCas9	negative selection	1597671
17115467	17115490	10	-	26627737	HeLa	viability after 15 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	0.40510093757000065	[567]	[182,408,329]	3	hSpCas9	negative selection	1597672
17129227	17129250	10	-	26627737	HeLa	viability after 15 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.042661774002151154	[501]	[164,160,313]	0	hSpCas9	negative selection	1597673
17129689	17129712	10	-	26627737	HeLa	viability after 15 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.10261720558937165	[332]	[274,86,66]	0	hSpCas9	negative selection	1597674
17105545	17105568	10	+	26627737	HeLa	viability after 18 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.5611000855306418	[995]	[294,639,582]	4	hSpCas9	negative selection	1679984
17110900	17110923	10	+	26627737	HeLa	viability after 18 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	-0.637624626869768	[494]	[203,10,63]	-5	hSpCas9	negative selection	1679985
17114077	17114100	10	+	26627737	HeLa	viability after 18 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	0.019804405999991698	[349]	[127,35,202]	0	hSpCas9	negative selection	1679986
17115467	17115490	10	-	26627737	HeLa	viability after 18 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	0.39460589079748964	[567]	[118,337,329]	3	hSpCas9	negative selection	1679987
17129227	17129250	10	-	26627737	HeLa	viability after 18 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.04491728634441183	[501]	[109,134,313]	0	hSpCas9	negative selection	1679988
17129689	17129712	10	-	26627737	HeLa	viability after 18 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.19466398922295766	[332]	[199,75,66]	1	hSpCas9	negative selection	1679989
17105545	17105568	10	+	26627737	HCT116	viability after 6 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.5566536633462504	[2296]	[670,453]	3	hSpCas9	negative selection	1762299
17110900	17110923	10	+	26627737	HCT116	viability after 6 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.2624101733855797	[550]	[168,67]	1	hSpCas9	negative selection	1762300
17114077	17114100	10	+	26627737	HCT116	viability after 6 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	-1.149880029291793	[546]	[50,31]	-6	hSpCas9	negative selection	1762301
17115467	17115490	10	-	26627737	HCT116	viability after 6 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-0.7401875049656015	[1112]	[145,81]	-4	hSpCas9	negative selection	1762302
17129227	17129250	10	-	26627737	HCT116	viability after 6 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	-0.4330952027312617	[706]	[149,44]	-2	hSpCas9	negative selection	1762303
17129689	17129712	10	-	26627737	HCT116	viability after 6 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	1.5660811602158202	[141]	[136,26]	7	hSpCas9	negative selection	1762304
17105545	17105568	10	+	26627737	HCT116	viability after 8 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	-0.03397334810046848	[1273]	[658,667,728]	0	hSpCas9	negative selection	1844614
17110900	17110923	10	+	26627737	HCT116	viability after 8 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.04863816188066015	[281]	[172,117,190]	0	hSpCas9	negative selection	1844615
17114077	17114100	10	+	26627737	HCT116	viability after 8 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	0.41496308994903375	[139]	[82,187,37]	4	hSpCas9	negative selection	1844616
17115467	17115490	10	-	26627737	HCT116	viability after 8 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-0.029686383060812283	[499]	[281,181,344]	0	hSpCas9	negative selection	1844617
17129227	17129250	10	-	26627737	HCT116	viability after 8 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	1.2339737333839547	[216]	[267,333,241]	8	hSpCas9	negative selection	1844618
17129689	17129712	10	-	26627737	HCT116	viability after 8 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.5655792380231353	[86]	[39,76,94]	5	hSpCas9	negative selection	1844619
17105545	17105568	10	+	26627737	HCT116	viability after 9 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.16259897879278173	[2296]	[838,565]	1	hSpCas9	negative selection	1926929
17110900	17110923	10	+	26627737	HCT116	viability after 9 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.7550060504994687	[550]	[192,291]	5	hSpCas9	negative selection	1926930
17114077	17114100	10	+	26627737	HCT116	viability after 9 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	-1.0659598405145991	[546]	[133,18]	-6	hSpCas9	negative selection	1926931
17115467	17115490	10	-	26627737	HCT116	viability after 9 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-2.0644030049993947	[1112]	[60,78]	-8	hSpCas9	negative selection	1926932
17129227	17129250	10	-	26627737	HCT116	viability after 9 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	-1.7613679100999664	[706]	[72,41]	-8	hSpCas9	negative selection	1926933
17129689	17129712	10	-	26627737	HCT116	viability after 9 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	1.8489992751646118	[141]	[149,125]	9	hSpCas9	negative selection	1926934
17105545	17105568	10	+	26627737	HCT116	viability after 12 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.1359864283857668	[1273]	[645,777,791]	1	hSpCas9	negative selection	2009244
17110900	17110923	10	+	26627737	HCT116	viability after 12 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.050663298521724576	[281]	[106,129,226]	0	hSpCas9	negative selection	2009245
17114077	17114100	10	+	26627737	HCT116	viability after 12 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	0.07277789502279042	[139]	[109,65,52]	0	hSpCas9	negative selection	2009246
17115467	17115490	10	-	26627737	HCT116	viability after 12 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	0.19058999764724005	[499]	[455,179,246]	2	hSpCas9	negative selection	2009247
17129227	17129250	10	-	26627737	HCT116	viability after 12 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	1.2442667146884203	[216]	[235,291,285]	8	hSpCas9	negative selection	2009248
17129689	17129712	10	-	26627737	HCT116	viability after 12 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.5478181737853578	[86]	[50,111,39]	5	hSpCas9	negative selection	2009249
17105545	17105568	10	+	26627737	HCT116	viability after 15 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.24512716337734375	[1273]	[812,1174,609]	2	hSpCas9	negative selection	2091559
17110900	17110923	10	+	26627737	HCT116	viability after 15 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	-0.30690289626598555	[281]	[243,71,90]	-3	hSpCas9	negative selection	2091560
17114077	17114100	10	+	26627737	HCT116	viability after 15 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	0.5695169937429132	[139]	[84,250,18]	5	hSpCas9	negative selection	2091561
17115467	17115490	10	-	26627737	HCT116	viability after 15 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-0.09866400759964722	[499]	[427,131,263]	-1	hSpCas9	negative selection	2091562
17129227	17129250	10	-	26627737	HCT116	viability after 15 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.6622676784326296	[216]	[139,188,254]	6	hSpCas9	negative selection	2091563
17129689	17129712	10	-	26627737	HCT116	viability after 15 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.957446115789507	[86]	[163,102,32]	7	hSpCas9	negative selection	2091564
17105545	17105568	10	+	26627737	HCT116	viability after 18 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.032245875902655374	[1273]	[416,832,625]	0	hSpCas9	negative selection	2173874
17110900	17110923	10	+	26627737	HCT116	viability after 18 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.7992254094183808	[281]	[390,128,196]	6	hSpCas9	negative selection	2173875
17114077	17114100	10	+	26627737	HCT116	viability after 18 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	1.5856004403214194	[139]	[147,314,135]	9	hSpCas9	negative selection	2173876
17115467	17115490	10	-	26627737	HCT116	viability after 18 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-0.2843386149075511	[499]	[200,149,249]	-3	hSpCas9	negative selection	2173877
17129227	17129250	10	-	26627737	HCT116	viability after 18 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.9773558356927116	[216]	[182,178,261]	7	hSpCas9	negative selection	2173878
17129689	17129712	10	-	26627737	HCT116	viability after 18 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	1.293210700545619	[86]	[67,187,44]	8	hSpCas9	negative selection	2173879
17037987	17038010	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAATGCAATGGTGCGATCCCAG	CUBN	ENSG00000107611	0.11455650635684256	[246,54]	[55,11]	0	dCas9-VP64	positive selection	2387349
16916863	16916886	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGTGCAGTGGCGCAATCTCGG	CUBN	ENSG00000107611	-0.2852829427171778	[144,33]	[27,1]	-1	dCas9-VP64	positive selection	2401772
16946685	16946708	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCGTCATGTTGGCCGGG	CUBN	ENSG00000107611	-0.08437565892322141	[6,12]	[1,0]	0	dCas9-VP64	positive selection	2405616
16865154	16865177	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGACGGGGTTTCACCATGTAGG	CUBN	ENSG00000107611	1.7100356304154607	[4,2]	[3,0]	6	dCas9-VP64	positive selection	2409731
16827675	16827698	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCCGCCTCCCTGG	CUBN	ENSG00000107611	0.6259309833286419	[228,309]	[35,151]	2	dCas9-VP64	positive selection	2450548
16946519	16946542	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCACTCTGTTGCCCAAG	CUBN	ENSG00000107611	-0.8039407674710506	[25,109]	[4,11]	-4	dCas9-VP64	positive selection	2453830
17037987	17038010	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAATGCAATGGTGCGATCCCAG	CUBN	ENSG00000107611	0.07566186633737754	[123,60]	[24,37]	0	dCas9-VP64	positive selection	2482604
16916863	16916886	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGTGCAGTGGCGCAATCTCGG	CUBN	ENSG00000107611	-1.049841376822195	[220,84]	[18,27]	-8	dCas9-VP64	positive selection	2497027
16946685	16946708	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCGTCATGTTGGCCGGG	CUBN	ENSG00000107611	-0.9208015753873722	[12,58]	[1,8]	-8	dCas9-VP64	positive selection	2500871
16865154	16865177	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGACGGGGTTTCACCATGTAGG	CUBN	ENSG00000107611	-0.28524240662887035	[88,68]	[26,14]	-3	dCas9-VP64	positive selection	2504986
16827675	16827698	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCCGCCTCCCTGG	CUBN	ENSG00000107611	0.8832307312434098	[227,267]	[69,222]	6	dCas9-VP64	positive selection	2545803
16946519	16946542	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCACTCTGTTGCCCAAG	CUBN	ENSG00000107611	-0.1109200555519485	[37,10]	[8,4]	-1	dCas9-VP64	positive selection	2549085
17088296	17088319	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-1.5400489281509668	[3,3]	[0,0]	-9	hSpCas9	positive selection	2981850
17110955	17110978	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.26767946228058104	[3,3]	[3,3]	6	hSpCas9	positive selection	2981851
17019852	17019875	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGAAATCCTTTCTCACGGCGG	CUBN	ENSG00000107611	0.30825263943619374	[4,3]	[5,3]	6	hSpCas9	positive selection	2981852
17065539	17065562	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAAGAAGCCTTCATAAGCGAGG	CUBN	ENSG00000107611	-0.07041168357178731	[3,4]	[3,2]	-1	hSpCas9	positive selection	2981853
17088296	17088319	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.5646985030195975	[3,3]	[1,0]	-7	hSpCas9	positive selection	3049708
17110955	17110978	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	-0.0022345429871967887	[3,3]	[2,1]	0	hSpCas9	positive selection	3049709
17019852	17019875	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGAAATCCTTTCTCACGGCGG	CUBN	ENSG00000107611	0.11306658996707694	[4,4]	[3,2]	2	hSpCas9	positive selection	3049710
17065539	17065562	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAAGAAGCCTTCATAAGCGAGG	CUBN	ENSG00000107611	-0.00625853049768299	[3,3]	[3,1]	0	hSpCas9	positive selection	3049711
17127828	17127851		-	24336571	A375	resistance to PLX after 7 days	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	1.0677378720077926	[11,8]	[24,18]	9	hSpCas9	positive selection	3108075
17127887	17127910		-	24336571	A375	resistance to PLX after 7 days	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.07528880544464389	[1,1]	[1,1]	2	hSpCas9	positive selection	3108076
17126754	17126777		+	24336571	A375	resistance to PLX after 7 days	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.16347174010930132	[8,8]	[9,10]	5	hSpCas9	positive selection	3108077
17126771	17126794		-	24336571	A375	resistance to PLX after 7 days	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	-0.46658709415291955	[1,3]	[1,1]	-9	hSpCas9	positive selection	3108078
17127828	17127851		-	24336571	A375	resistance to PLX after 14 days	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	6.018283032734524	[9,10]	[283,404]	9	hSpCas9	positive selection	3165868
17127887	17127910		-	24336571	A375	resistance to PLX after 14 days	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	1.0464190105523825	[1,1]	[1,1]	8	hSpCas9	positive selection	3165869
17126754	17126777		+	24336571	A375	resistance to PLX after 14 days	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	1.2344383479820122	[9,7]	[10,8]	8	hSpCas9	positive selection	3165870
17126771	17126794		-	24336571	A375	resistance to PLX after 14 days	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.4163793647083416	[3,1]	[1,1]	4	hSpCas9	positive selection	3165871
17127828	17127851		-	24336571	A375	viability after 7 days	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.4217815367561868	[14]	[11,8]	-6	hSpCas9	negative selection	3223661
17127887	17127910		-	24336571	A375	viability after 7 days	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-1.0221026084260485	[4]	[1,1]	-9	hSpCas9	negative selection	3223662
17126754	17126777		+	24336571	A375	viability after 7 days	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	-0.07764593583371732	[9]	[8,8]	-1	hSpCas9	negative selection	3223663
17126771	17126794		-	24336571	A375	viability after 7 days	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	-0.9562052433726497	[6]	[1,3]	-8	hSpCas9	negative selection	3223664
17127828	17127851		-	24336571	A375	viability after 14 days	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.32722964452837694	[14]	[9,10]	-4	hSpCas9	negative selection	3281454
17127887	17127910		-	24336571	A375	viability after 14 days	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-1.2078600150961694	[4]	[1,1]	-9	hSpCas9	negative selection	3281455
17126754	17126777		+	24336571	A375	viability after 14 days	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	-0.11731254368224919	[9]	[9,7]	-1	hSpCas9	negative selection	3281456
17126771	17126794		-	24336571	A375	viability after 14 days	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	-1.163575664407158	[6]	[3,1]	-9	hSpCas9	negative selection	3281457
17123591	17123614	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.7109865275853728	[87,98]	[0,0]	3	hSpCas9	positive selection	3345021
17126754	17126777	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	-1.623897737796692	[476,465]	[0,0]	-9	hSpCas9	positive selection	3345022
17123577	17123600	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	-0.09556106650438732	[158,167]	[0,0]	0	hSpCas9	positive selection	3345023
17127828	17127851	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.9905396707509337	[76,76]	[0,0]	4	hSpCas9	positive selection	3364243
17127887	17127910	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	1.2349583984173806	[64,64]	[0,0]	5	hSpCas9	positive selection	3364244
17126771	17126794	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	5.280046287945918	[62,62]	[15,15]	9	hSpCas9	positive selection	3364245
17088296	17088319	10	-	26780180	HT29	viability (Avana library 4 designs)	ACGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	1.7064764070616	[]	[]	6	hSpCas9	negative selection	3418517
17110954	17110977	10	+	26780180	HT29	viability (Avana library 4 designs)	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	1.31008678801011	[]	[]	5	hSpCas9	negative selection	3418518
17019851	17019874	10	+	26780180	HT29	viability (Avana library 4 designs)	TCTGAAATCCTTTCTCACGGCGG	CUBN	ENSG00000107611	0.829201377001915	[]	[]	3	hSpCas9	negative selection	3418519
17065538	17065561	10	+	26780180	HT29	viability (Avana library 4 designs)	TTAAGAAGCCTTCATAAGCGAGG	CUBN	ENSG00000107611	0.6886813620242	[]	[]	2	hSpCas9	negative selection	3418520
17088296	17088319	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	1.55344717647641	[]	[]	2	hSpCas9	negative selection	3497239
17065538	17065561	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTAAGAAGCCTTCATAAGCGAGG	CUBN	ENSG00000107611	1.8681547214585	[]	[]	2	hSpCas9	negative selection	3497240
17019851	17019874	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGAAATCCTTTCTCACGGCGG	CUBN	ENSG00000107611	1.25638606436189	[]	[]	1	hSpCas9	negative selection	3497241
17110954	17110977	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.0683045268616407	[]	[]	0	hSpCas9	negative selection	3497242
17114157	17114180	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	3.8285262882798	[]	[]	6	hSpCas9	negative selection	3497243
17084344	17084367	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	TATATGATGAAGCAGCCCCAGGG	CUBN	ENSG00000107611	1.06285328685061	[]	[]	1	hSpCas9	negative selection	3497244
17088296	17088319	10	-	26780180	A375	viability (Avana lentiGuide)	ACGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	1.57488583242217	[]	[]	1	hSpCas9	negative selection	3605898
17065538	17065561	10	+	26780180	A375	viability (Avana lentiGuide)	TTAAGAAGCCTTCATAAGCGAGG	CUBN	ENSG00000107611	0.212355106312567	[]	[]	0	hSpCas9	negative selection	3605899
17019851	17019874	10	+	26780180	A375	viability (Avana lentiGuide)	TCTGAAATCCTTTCTCACGGCGG	CUBN	ENSG00000107611	-0.00375471635340574	[]	[]	0	hSpCas9	negative selection	3605900
17110954	17110977	10	+	26780180	A375	viability (Avana lentiGuide)	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	-3.11334309378459	[]	[]	-5	hSpCas9	negative selection	3605901
17114157	17114180	10	-	26780180	A375	viability (Avana lentiGuide)	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	0.639988704194065	[]	[]	0	hSpCas9	negative selection	3605902
17084344	17084367	10	-	26780180	A375	viability (Avana lentiGuide)	TATATGATGAAGCAGCCCCAGGG	CUBN	ENSG00000107611	-3.90097961254435	[]	[]	-6	hSpCas9	negative selection	3605903
17088296	17088319	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.028288856495025858	[5]	[4,4]	0	hSpCas9	positive selection	3714557
17065538	17065561	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAAGAAGCCTTCATAAGCGAGG	CUBN	ENSG00000107611	-0.02438284767765142	[6]	[6,5]	0	hSpCas9	positive selection	3714558
17019851	17019874	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGAAATCCTTTCTCACGGCGG	CUBN	ENSG00000107611	-0.23924960960771785	[4]	[4,2]	-4	hSpCas9	positive selection	3714559
17110954	17110977	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.0275017931135388	[5]	[4,5]	0	hSpCas9	positive selection	3714560
17114157	17114180	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	0.4362328978243904	[4]	[6,5]	9	hSpCas9	positive selection	3714561
17084344	17084367	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATATGATGAAGCAGCCCCAGGG	CUBN	ENSG00000107611	-0.07787373026879837	[5]	[5,5]	-1	hSpCas9	positive selection	3714562
17088296	17088319	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	0.024545731440158494	[5]	[4,4]	0	hSpCas9	positive selection	3823164
17065538	17065561	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAAGAAGCCTTCATAAGCGAGG	CUBN	ENSG00000107611	-0.3066386080164769	[6]	[4,2]	-4	hSpCas9	positive selection	3823165
17019851	17019874	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGAAATCCTTTCTCACGGCGG	CUBN	ENSG00000107611	-0.53518162379832	[5]	[0,5]	-6	hSpCas9	positive selection	3823166
17110954	17110977	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.32558585759448266	[5]	[4,6]	8	hSpCas9	positive selection	3823167
17114157	17114180	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	0.16782953244807605	[5]	[5,5]	4	hSpCas9	positive selection	3823168
17084344	17084367	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATATGATGAAGCAGCCCCAGGG	CUBN	ENSG00000107611	0.10629235665790432	[6]	[6,4]	2	hSpCas9	positive selection	3823169
17127828	17127851	10	-	26780180	A375	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.766400731109534	[]	[]	3	hSpCas9	negative selection	3930656
17123577	17123600	10	+	26780180	A375	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.530286993908237	[]	[]	1	hSpCas9	negative selection	3930657
17127887	17127910	10	-	26780180	A375	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.526582988175561	[]	[]	1	hSpCas9	negative selection	3930658
17126754	17126777	10	+	26780180	A375	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.404583382454565	[]	[]	1	hSpCas9	negative selection	3930659
17126771	17126794	10	-	26780180	A375	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.963731152748621	[]	[]	4	hSpCas9	negative selection	3930660
17123591	17123614	10	-	26780180	A375	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	1.04277305759822	[]	[]	5	hSpCas9	negative selection	3930661
17127828	17127851	10	-	26780180	HT29	viability (GeCKOv2 library)	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	1.06172149555781	[]	[]	5	hSpCas9	negative selection	4038622
17123577	17123600	10	+	26780180	HT29	viability (GeCKOv2 library)	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	-0.002489070683955	[]	[]	0	hSpCas9	negative selection	4038623
17127887	17127910	10	-	26780180	HT29	viability (GeCKOv2 library)	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.846640824883878	[]	[]	3	hSpCas9	negative selection	4038624
17126754	17126777	10	+	26780180	HT29	viability (GeCKOv2 library)	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.210192570173014	[]	[]	0	hSpCas9	negative selection	4038625
17126771	17126794	10	-	26780180	HT29	viability (GeCKOv2 library)	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.682626831405269	[]	[]	2	hSpCas9	negative selection	4038626
17123591	17123614	10	-	26780180	HT29	viability (GeCKOv2 library)	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	1.49327871423052	[]	[]	7	hSpCas9	negative selection	4038627
17127828	17127851	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.9467844611405886	[3]	[1,8]	9	hSpCas9	positive selection	4130399
17127887	17127910	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.20908073424974893	[0]	[0,0]	-5	hSpCas9	positive selection	4130400
17126754	17126777	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.20349681333269126	[2]	[0,3]	5	hSpCas9	positive selection	4130401
17126771	17126794	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	-0.17480771985779198	[1]	[0,0]	-4	hSpCas9	positive selection	4130402
17127828	17127851	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.013693011337308946	[3]	[0,2,3,0]	0	hSpCas9	positive selection	4194421
17127887	17127910	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	1.1018546286486577	[0]	[0,0,0,0]	8	hSpCas9	positive selection	4194422
17126754	17126777	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	1.5100676921890992	[2]	[3,4,0,4]	9	hSpCas9	positive selection	4194423
17126771	17126794	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	-0.8455124190768495	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4194424
17123591	17123614	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.01710371654035293	[2]	[3,0]	0	hSpCas9	positive selection	4265458
17126754	17126777	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.442387854550418	[4]	[4,4]	8	hSpCas9	positive selection	4265459
17123577	17123600	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.5485057010427202	[3]	[3,3]	9	hSpCas9	positive selection	4265460
17127828	17127851	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.07562426798229821	[1]	[2,0]	1	hSpCas9	positive selection	4329729
17127887	17127910	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.3248605110966235	[1]	[2,1]	6	hSpCas9	positive selection	4329730
17126771	17126794	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.6719007644717957	[1]	[1,2]	9	hSpCas9	positive selection	4329731
16990406	16990428	10	-	27760321	OCIAML3	viability	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	1.0459408545632964	[500,415]	[655,842]	9	hSpCas9	negative selection	4392570
17045149	17045171	10	+	27760321	OCIAML3	viability	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	0.5387653311782349	[516,460]	[424,723]	6	hSpCas9	negative selection	4392571
17045174	17045196	10	+	27760321	OCIAML3	viability	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	0.2607535161818288	[597,464]	[372,652]	3	hSpCas9	negative selection	4392572
17088296	17088318	10	-	27760321	OCIAML3	viability	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.29377304214430167	[520,473]	[288,353]	-3	hSpCas9	negative selection	4392573
17115567	17115589	10	+	27760321	OCIAML3	viability	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	-0.13903789194819138	[724,687]	[474,537]	-1	hSpCas9	negative selection	4392574
16990406	16990428	10	-	27760321	OCIAML2	viability	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	-0.2354227852369713	[500,415]	[273,365]	-3	hSpCas9	negative selection	4476033
17045149	17045171	10	+	27760321	OCIAML2	viability	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	0.3972555216439365	[516,460]	[546,484]	5	hSpCas9	negative selection	4476034
17045174	17045196	10	+	27760321	OCIAML2	viability	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	0.03077693506618101	[597,464]	[411,467]	0	hSpCas9	negative selection	4476035
17088296	17088318	10	-	27760321	OCIAML2	viability	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.3101083048155111	[520,473]	[241,432]	-4	hSpCas9	negative selection	4476036
17115567	17115589	10	+	27760321	OCIAML2	viability	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	-0.08794137296064763	[724,687]	[508,576]	-1	hSpCas9	negative selection	4476037
16990406	16990428	10	-	27760321	MV411	viability	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	0.9955267019733903	[500,415]	[415,877]	7	hSpCas9	negative selection	4559496
17045149	17045171	10	+	27760321	MV411	viability	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	0.6879966698946516	[516,460]	[439,637]	5	hSpCas9	negative selection	4559497
17045174	17045196	10	+	27760321	MV411	viability	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	0.6021182076384999	[597,464]	[142,1107]	4	hSpCas9	negative selection	4559498
17088296	17088318	10	-	27760321	MV411	viability	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	0.17426228026340113	[520,473]	[165,676]	1	hSpCas9	negative selection	4559499
17115567	17115589	10	+	27760321	MV411	viability	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	0.055184963661479736	[724,687]	[422,577]	0	hSpCas9	negative selection	4559500
16990406	16990428	10	-	27760321	HL60	viability	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	0.3199273846567682	[500,415]	[448,482]	4	hSpCas9	negative selection	4642959
17045149	17045171	10	+	27760321	HL60	viability	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	0.26922699667700734	[516,460]	[570,384]	3	hSpCas9	negative selection	4642960
17045174	17045196	10	+	27760321	HL60	viability	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	0.6383641433429068	[597,464]	[640,702]	7	hSpCas9	negative selection	4642961
17088296	17088318	10	-	27760321	HL60	viability	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.28908588151365144	[520,473]	[378,282]	-3	hSpCas9	negative selection	4642962
17115567	17115589	10	+	27760321	HL60	viability	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	0.24325866749446223	[724,687]	[696,669]	3	hSpCas9	negative selection	4642963
16990406	16990428	10	-	27760321	HT1080	viability	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	0.2613211696187319	[415,324]	[132,224]	1	hSpCas9	negative selection	4726422
17045149	17045171	10	+	27760321	HT1080	viability	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	0.8955128548372442	[460,359]	[329,275]	5	hSpCas9	negative selection	4726423
17045174	17045196	10	+	27760321	HT1080	viability	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	0.08382468064928955	[464,362]	[180,167]	0	hSpCas9	negative selection	4726424
17088296	17088318	10	-	27760321	HT1080	viability	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.08770360491930926	[473,369]	[193,118]	0	hSpCas9	negative selection	4726425
17115567	17115589	10	+	27760321	HT1080	viability	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	-0.4167050508700544	[687,536]	[209,152]	-2	hSpCas9	negative selection	4726426
16990406	16990428	10	-	27760321	HT29	viability after 7 days	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	0.5001186896849011	[415,324]	[811,584,643]	7	hSpCas9	negative selection	4809885
17045149	17045171	10	+	27760321	HT29	viability after 7 days	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	0.04017983072429765	[460,359]	[683,595,372]	0	hSpCas9	negative selection	4809886
17045174	17045196	10	+	27760321	HT29	viability after 7 days	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	0.5027717044949781	[464,362]	[848,827,602]	7	hSpCas9	negative selection	4809887
17088296	17088318	10	-	27760321	HT29	viability after 7 days	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.7773756922925378	[473,369]	[453,299,217]	-8	hSpCas9	negative selection	4809888
17115567	17115589	10	+	27760321	HT29	viability after 7 days	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	-0.12930599472973903	[687,536]	[756,934,479]	-2	hSpCas9	negative selection	4809889
16990406	16990428	10	-	27760321	HT29	viability after 25 days	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	0.4738867363286785	[415,324]	[638,551,566]	5	hSpCas9	negative selection	4893348
17045149	17045171	10	+	27760321	HT29	viability after 25 days	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	0.19934963140907286	[460,359]	[503,370,765]	2	hSpCas9	negative selection	4893349
17045174	17045196	10	+	27760321	HT29	viability after 25 days	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	0.1626145223670285	[464,362]	[487,577,523]	1	hSpCas9	negative selection	4893350
17088296	17088318	10	-	27760321	HT29	viability after 25 days	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.36407840167307903	[473,369]	[299,386,448]	-4	hSpCas9	negative selection	4893351
17115567	17115589	10	+	27760321	HT29	viability after 25 days	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	0.2881309824413477	[687,536]	[706,1054,804]	3	hSpCas9	negative selection	4893352
16990406	16990428	10	-	27760321	HT29	viability after 22 days	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	0.33395564507636094	[415,324]	[536,520,561]	3	hSpCas9	negative selection	4976811
17045149	17045171	10	+	27760321	HT29	viability after 22 days	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	0.6363882085939696	[460,359]	[819,739,649]	7	hSpCas9	negative selection	4976812
17045174	17045196	10	+	27760321	HT29	viability after 22 days	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	0.1931292494149251	[464,362]	[444,572,626]	2	hSpCas9	negative selection	4976813
17088296	17088318	10	-	27760321	HT29	viability after 22 days	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.2861018547854565	[473,369]	[453,221,523]	-3	hSpCas9	negative selection	4976814
17115567	17115589	10	+	27760321	HT29	viability after 22 days	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	-0.06246395960746598	[687,536]	[555,856,623]	0	hSpCas9	negative selection	4976815
16990406	16990428	10	-	27760321	HT29	viability after 19 days	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	0.9153719834671057	[415,324]	[781,509,1091]	8	hSpCas9	negative selection	5060274
17045149	17045171	10	+	27760321	HT29	viability after 19 days	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	0.3214426389682708	[460,359]	[764,552,464]	3	hSpCas9	negative selection	5060275
17045174	17045196	10	+	27760321	HT29	viability after 19 days	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	0.5041048125365307	[464,362]	[476,851,664]	5	hSpCas9	negative selection	5060276
17088296	17088318	10	-	27760321	HT29	viability after 19 days	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.12298423372504709	[473,369]	[418,336,565]	-1	hSpCas9	negative selection	5060277
17115567	17115589	10	+	27760321	HT29	viability after 19 days	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	-0.14656140529474104	[687,536]	[569,969,361]	-1	hSpCas9	negative selection	5060278
16990406	16990428	10	-	27760321	HT29	viability after 16 days	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	0.3730724936317678	[415,324]	[448,507,645]	4	hSpCas9	negative selection	5143737
17045149	17045171	10	+	27760321	HT29	viability after 16 days	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	0.6213922890501709	[460,359]	[656,623,835]	7	hSpCas9	negative selection	5143738
17045174	17045196	10	+	27760321	HT29	viability after 16 days	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	-0.012511391733395633	[464,362]	[586,442,359]	0	hSpCas9	negative selection	5143739
17088296	17088318	10	-	27760321	HT29	viability after 16 days	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.4659133994443788	[473,369]	[416,362,251]	-5	hSpCas9	negative selection	5143740
17115567	17115589	10	+	27760321	HT29	viability after 16 days	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	0.4630526316945255	[687,536]	[1062,939,841]	5	hSpCas9	negative selection	5143741
16990406	16990428	10	-	27760321	HT29	viability after 13 days	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	0.4753815075080692	[415,324]	[799,560,440]	6	hSpCas9	negative selection	5227200
17045149	17045171	10	+	27760321	HT29	viability after 13 days	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	-0.030020245114220107	[460,359]	[281,537,572]	0	hSpCas9	negative selection	5227201
17045174	17045196	10	+	27760321	HT29	viability after 13 days	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	0.1256700100176556	[464,362]	[453,694,428]	1	hSpCas9	negative selection	5227202
17088296	17088318	10	-	27760321	HT29	viability after 13 days	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.5944662193639704	[473,369]	[266,282,416]	-6	hSpCas9	negative selection	5227203
17115567	17115589	10	+	27760321	HT29	viability after 13 days	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	-0.03592787239544226	[687,536]	[654,641,776]	0	hSpCas9	negative selection	5227204
16990406	16990428	10	-	27760321	HT29	viability after 10 days	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	0.501448292404776	[415,324]	[895,414,646]	6	hSpCas9	negative selection	5310663
17045149	17045171	10	+	27760321	HT29	viability after 10 days	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	0.06106923913404283	[460,359]	[563,680,366]	0	hSpCas9	negative selection	5310664
17045174	17045196	10	+	27760321	HT29	viability after 10 days	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	0.4150723610478664	[464,362]	[786,633,645]	5	hSpCas9	negative selection	5310665
17088296	17088318	10	-	27760321	HT29	viability after 10 days	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-0.6296108474167027	[473,369]	[308,241,464]	-6	hSpCas9	negative selection	5310666
17115567	17115589	10	+	27760321	HT29	viability after 10 days	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	0.2519987791173811	[687,536]	[869,949,912]	3	hSpCas9	negative selection	5310667
16990406	16990428	10	-	27760321	MOLM13	viability	GTACATTAGGACGGACCCCGGG	CUBN	ENSG00000107611	0.2424029640049436	[500,415]	[476,157]	1	hSpCas9	negative selection	5394126
17045149	17045171	10	+	27760321	MOLM13	viability	ATGAACGTGCCGCTTGAAGTGG	CUBN	ENSG00000107611	1.0663713014684468	[516,460]	[570,581]	7	hSpCas9	negative selection	5394127
17045174	17045196	10	+	27760321	MOLM13	viability	GATTACCCCCGCAACCTACAGG	CUBN	ENSG00000107611	-0.012542529480317255	[597,464]	[305,285]	0	hSpCas9	negative selection	5394128
17088296	17088318	10	-	27760321	MOLM13	viability	CGGTTCTATTAAGTCTCCGGGG	CUBN	ENSG00000107611	-1.7821667699512123	[520,473]	[147,24]	-7	hSpCas9	negative selection	5394129
17115567	17115589	10	+	27760321	MOLM13	viability	GGGTCCGTACGTCTCAGGTGGG	CUBN	ENSG00000107611	0.38219454372949524	[724,687]	[659,400]	2	hSpCas9	negative selection	5394130
17129576	17129599	10	+	27661255	K562	viability	GCTATTTGGGAAAACTGGTGAGG	CUBN	ENSG00000107611	0.10482428860153226	[142,245]	[158,170]	3	dCas9-KRAB	negative selection	5473367
17129373	17129396	10	-	27661255	K562	viability	GCAGATGAGCAGGGGCAGTTGGG	CUBN	ENSG00000107611	-0.07246603895122664	[850,722]	[604,594]	-3	dCas9-KRAB	negative selection	5473368
17123591	17123614	10	-	27260156	BXPC3	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.046125806681455335	[438]	[363,441,571,537]	1	hSpCas9	negative selection	5537918
17126754	17126777	10	+	27260156	BXPC3	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.29927344109344256	[1106]	[1232,1291,1385,1857]	6	hSpCas9	negative selection	5537919
17123577	17123600	10	+	27260156	BXPC3	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.4111396849973017	[530]	[605,744,803,817]	8	hSpCas9	negative selection	5537920
17127828	17127851	10	-	27260156	BXPC3	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.02792916596621753	[196]	[138,271,244,183]	0	hSpCas9	negative selection	5602189
17127887	17127910	10	-	27260156	BXPC3	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.17040022305051816	[193]	[160,281,177,302]	4	hSpCas9	negative selection	5602190
17126771	17126794	10	-	27260156	BXPC3	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.3749792473501352	[136]	[161,198,202,178]	7	hSpCas9	negative selection	5602191
17123591	17123614	10	-	27260156	A673	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.19678890402990865	[438]	[778,495,454,715]	5	hSpCas9	negative selection	5659169
17126754	17126777	10	+	27260156	A673	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.2787500923474948	[1106]	[1655,1657,1414,1729]	6	hSpCas9	negative selection	5659170
17123577	17123600	10	+	27260156	A673	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.5002662750620116	[530]	[838,946,895,915]	9	hSpCas9	negative selection	5659171
17127828	17127851	10	-	27260156	A673	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.12768206076413002	[196]	[245,150,261,210]	-3	hSpCas9	negative selection	5723440
17127887	17127910	10	-	27260156	A673	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.3966356886433462	[193]	[242,174,158,135]	-7	hSpCas9	negative selection	5723441
17126771	17126794	10	-	27260156	A673	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.157753041517124	[136]	[193,176,166,197]	4	hSpCas9	negative selection	5723442
17123591	17123614	10	-	27260156	A375	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.1262729655174052	[438]	[601,607,478,554]	1	hSpCas9	negative selection	5780420
17126754	17126777	10	+	27260156	A375	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.5080200965399564	[1106]	[1765,2093,1797,1736]	7	hSpCas9	negative selection	5780421
17123577	17123600	10	+	27260156	A375	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.3612321108351243	[530]	[631,975,873,732]	5	hSpCas9	negative selection	5780422
17127828	17127851	10	-	27260156	A375	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.017647264487241632	[196]	[176,240,201,302]	0	hSpCas9	negative selection	5844691
17127887	17127910	10	-	27260156	A375	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.24290403389204873	[193]	[289,311,218,257]	3	hSpCas9	negative selection	5844692
17126771	17126794	10	-	27260156	A375	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.2677024348358428	[136]	[147,168,263,185]	4	hSpCas9	negative selection	5844693
17123591	17123614	10	-	27260156	COLO741	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	-0.059091571606276636	[438]	[636,569,423]	-1	hSpCas9	negative selection	5901671
17126754	17126777	10	+	27260156	COLO741	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.3675909412957581	[1106]	[1543,1878,2009]	7	hSpCas9	negative selection	5901672
17123577	17123600	10	+	27260156	COLO741	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.4170633486689663	[530]	[949,970,805]	8	hSpCas9	negative selection	5901673
17127828	17127851	10	-	27260156	COLO741	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.2460407081752336	[196]	[342,332,227]	5	hSpCas9	negative selection	5965942
17127887	17127910	10	-	27260156	COLO741	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.19533322128726405	[193]	[184,183,272]	-4	hSpCas9	negative selection	5965943
17126771	17126794	10	-	27260156	COLO741	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.46487283137246793	[136]	[286,268,176]	8	hSpCas9	negative selection	5965944
17123591	17123614	10	-	27260156	CAL120	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.22278296375812195	[438]	[617,635,654]	3	hSpCas9	negative selection	6022922
17126754	17126777	10	+	27260156	CAL120	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.5073357544347197	[1106]	[2794,1676,1534]	7	hSpCas9	negative selection	6022923
17123577	17123600	10	+	27260156	CAL120	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	-0.03403138001723205	[530]	[851,585,530]	0	hSpCas9	negative selection	6022924
17127828	17127851	10	-	27260156	CAL120	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.2759285419909485	[196]	[445,238,228]	4	hSpCas9	negative selection	6087193
17127887	17127910	10	-	27260156	CAL120	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.037732252372121966	[193]	[341,195,219]	0	hSpCas9	negative selection	6087194
17126771	17126794	10	-	27260156	CAL120	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.6014171758909579	[136]	[182,463,119]	8	hSpCas9	negative selection	6087195
17123591	17123614	10	-	27260156	CADOES1	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.3632701241682515	[438]	[491,447,602,558]	6	hSpCas9	negative selection	6144173
17126754	17126777	10	+	27260156	CADOES1	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.40602080542882835	[1106]	[1275,1663,1197,1317]	6	hSpCas9	negative selection	6144174
17123577	17123600	10	+	27260156	CADOES1	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.44499234783283514	[530]	[660,741,648,635]	7	hSpCas9	negative selection	6144175
17127828	17127851	10	-	27260156	CADOES1	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.17193456511212402	[196]	[137,123,238,148]	-3	hSpCas9	negative selection	6208444
17127887	17127910	10	-	27260156	CADOES1	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.3285746676180189	[193]	[195,270,250,186]	5	hSpCas9	negative selection	6208445
17126771	17126794	10	-	27260156	CADOES1	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.22808289235074408	[136]	[139,190,118,146]	4	hSpCas9	negative selection	6208446
17123591	17123614	10	-	27260156	EWS502	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.18927597974341315	[438]	[679,336,508,585]	3	hSpCas9	negative selection	6265424
17126754	17126777	10	+	27260156	EWS502	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.4023233102771189	[1106]	[1540,1501,1510,1647]	7	hSpCas9	negative selection	6265425
17123577	17123600	10	+	27260156	EWS502	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.6002790544116775	[530]	[614,800,1039,994]	9	hSpCas9	negative selection	6265426
17127828	17127851	10	-	27260156	EWS502	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.003998187663188935	[196]	[129,243,294,173]	0	hSpCas9	negative selection	6329695
17127887	17127910	10	-	27260156	EWS502	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.4784969240520779	[193]	[158,187,532,286]	8	hSpCas9	negative selection	6329696
17126771	17126794	10	-	27260156	EWS502	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.29309595895979834	[136]	[205,185,170,140]	5	hSpCas9	negative selection	6329697
17123591	17123614	10	-	27260156	EW8	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.32330467374729405	[438]	[614,471,376,345]	6	hSpCas9	negative selection	6386675
17126754	17126777	10	+	27260156	EW8	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.22282023857313793	[1106]	[1325,1074,851,995]	4	hSpCas9	negative selection	6386676
17123577	17123600	10	+	27260156	EW8	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.6756380851833729	[530]	[773,884,673,427]	9	hSpCas9	negative selection	6386677
17127828	17127851	10	-	27260156	EW8	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.11973823315055854	[196]	[180,148,87,182]	-2	hSpCas9	negative selection	6450946
17127887	17127910	10	-	27260156	EW8	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.3551826623205828	[193]	[311,129,139,243]	6	hSpCas9	negative selection	6450947
17126771	17126794	10	-	27260156	EW8	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.1790936128018621	[136]	[90,150,93,167]	3	hSpCas9	negative selection	6450948
17123591	17123614	10	-	27260156	CORL105	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	-0.11254462358212793	[438]	[431,453,431,574]	-2	hSpCas9	negative selection	6507926
17126754	17126777	10	+	27260156	CORL105	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.6024469313197214	[1106]	[1837,2153,2311,1612]	9	hSpCas9	negative selection	6507927
17123577	17123600	10	+	27260156	CORL105	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.49671980960066886	[530]	[793,928,875,904]	8	hSpCas9	negative selection	6507928
17127828	17127851	10	-	27260156	CORL105	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.23641286707892784	[196]	[132,214,293,153]	-4	hSpCas9	negative selection	6572197
17127887	17127910	10	-	27260156	CORL105	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.09951299361620292	[193]	[247,173,256,177]	-2	hSpCas9	negative selection	6572198
17126771	17126794	10	-	27260156	CORL105	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.4251011930705133	[136]	[189,244,234,192]	7	hSpCas9	negative selection	6572199
17123591	17123614	10	-	27260156	HS294T	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.09132324560926267	[438]	[100,147,114,404]	1	hSpCas9	negative selection	6629177
17126754	17126777	10	+	27260156	HS294T	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.37018778532749286	[1106]	[620,501,465,629]	5	hSpCas9	negative selection	6629178
17123577	17123600	10	+	27260156	HS294T	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.08770355926648465	[530]	[201,194,240,239]	1	hSpCas9	negative selection	6629179
17127828	17127851	10	-	27260156	HS294T	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.4192488796538921	[196]	[68,81,142,119]	5	hSpCas9	negative selection	6693448
17127887	17127910	10	-	27260156	HS294T	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.4074941832020105	[193]	[48,41,55,84]	-5	hSpCas9	negative selection	6693449
17126771	17126794	10	-	27260156	HS294T	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.477126570338809	[136]	[97,35,68,93]	6	hSpCas9	negative selection	6693450
17123591	17123614	10	-	27260156	HCC44	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.2895673748445556	[438]	[349,464,1215,496]	5	hSpCas9	negative selection	6750428
17126754	17126777	10	+	27260156	HCC44	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.4062575548197074	[1106]	[1688,1603,1924,1467]	6	hSpCas9	negative selection	6750429
17123577	17123600	10	+	27260156	HCC44	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.4715068023936163	[530]	[1048,660,684,943]	7	hSpCas9	negative selection	6750430
17127828	17127851	10	-	27260156	HCC44	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.32500230983916056	[196]	[302,197,295,331]	5	hSpCas9	negative selection	6814699
17127887	17127910	10	-	27260156	HCC44	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.3493754689712686	[193]	[236,145,540,252]	6	hSpCas9	negative selection	6814700
17126771	17126794	10	-	27260156	HCC44	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	1.1662646865376254	[136]	[325,483,366,197]	9	hSpCas9	negative selection	6814701
17123591	17123614	10	-	27260156	G402	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.147372559440174	[438]	[434,403,1053,450]	1	hSpCas9	negative selection	6871679
17126754	17126777	10	+	27260156	G402	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.43906633910817505	[1106]	[2062,1589,1950,1737]	5	hSpCas9	negative selection	6871680
17123577	17123600	10	+	27260156	G402	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.77094373455127	[530]	[865,1765,600,1184]	8	hSpCas9	negative selection	6871681
17127828	17127851	10	-	27260156	G402	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.275562628268201	[196]	[604,280,188,139]	3	hSpCas9	negative selection	6935950
17127887	17127910	10	-	27260156	G402	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.8496838866342995	[193]	[522,592,263,351]	9	hSpCas9	negative selection	6935951
17126771	17126794	10	-	27260156	G402	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.26554426925210883	[136]	[175,348,123,160]	3	hSpCas9	negative selection	6935952
17123591	17123614	10	-	27260156	L33	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.0725143794855574	[438]	[479,183,276,475]	1	hSpCas9	negative selection	6992930
17126754	17126777	10	+	27260156	L33	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.31943971975160057	[1106]	[1309,624,880,1290]	6	hSpCas9	negative selection	6992931
17123577	17123600	10	+	27260156	L33	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.3318832920475441	[530]	[700,266,489,541]	7	hSpCas9	negative selection	6992932
17127828	17127851	10	-	27260156	L33	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.2139352876675753	[196]	[275,104,101,217]	4	hSpCas9	negative selection	7057201
17127887	17127910	10	-	27260156	L33	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.10331784887515583	[193]	[161,66,107,224]	-2	hSpCas9	negative selection	7057202
17126771	17126794	10	-	27260156	L33	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.04973165617685038	[136]	[145,34,133,122]	1	hSpCas9	negative selection	7057203
17123591	17123614	10	-	27260156	K562	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	-0.5814008380508036	[438]	[153,562,168,171]	-6	hSpCas9	negative selection	7114181
17126754	17126777	10	+	27260156	K562	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.6021962988516003	[1106]	[1873,1226,1532,1357]	7	hSpCas9	negative selection	7114182
17123577	17123600	10	+	27260156	K562	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.5702415027431494	[530]	[861,393,743,782]	7	hSpCas9	negative selection	7114183
17127828	17127851	10	-	27260156	K562	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.32406319951635043	[196]	[60,232,91,448]	4	hSpCas9	negative selection	7178452
17127887	17127910	10	-	27260156	K562	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.15835854507042813	[193]	[110,180,174,147]	-2	hSpCas9	negative selection	7178453
17126771	17126794	10	-	27260156	K562	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	-0.6152013360786872	[136]	[111,43,82,78]	-6	hSpCas9	negative selection	7178454
17123591	17123614	10	-	27260156	HT29	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.33189148423075054	[438]	[711,709,726,553]	6	hSpCas9	negative selection	7235432
17126754	17126777	10	+	27260156	HT29	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.2383545587981324	[1106]	[1672,1927,1589,1227]	4	hSpCas9	negative selection	7235433
17123577	17123600	10	+	27260156	HT29	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.6813386391556673	[530]	[1038,1336,1006,804]	9	hSpCas9	negative selection	7235434
17127828	17127851	10	-	27260156	HT29	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.03981979698768523	[196]	[259,319,277,144]	0	hSpCas9	negative selection	7299703
17127887	17127910	10	-	27260156	HT29	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.14112934407640076	[193]	[213,370,276,190]	2	hSpCas9	negative selection	7299704
17126771	17126794	10	-	27260156	HT29	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.44775600209381383	[136]	[306,141,186,264]	8	hSpCas9	negative selection	7299705
17123591	17123614	10	-	27260156	MHHES1	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.08582229157500701	[438]	[552,582,457,505]	1	hSpCas9	negative selection	7356683
17126754	17126777	10	+	27260156	MHHES1	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.5220299216225461	[1106]	[1801,2165,1987,1316]	8	hSpCas9	negative selection	7356684
17123577	17123600	10	+	27260156	MHHES1	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.7630475810649608	[530]	[1204,784,1188,887]	9	hSpCas9	negative selection	7356685
17127828	17127851	10	-	27260156	MHHES1	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.5815112540545856	[196]	[489,338,293,238]	8	hSpCas9	negative selection	7420954
17127887	17127910	10	-	27260156	MHHES1	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.40952861986645805	[193]	[166,192,131,164]	-6	hSpCas9	negative selection	7420955
17126771	17126794	10	-	27260156	MHHES1	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	-0.0938505845676898	[136]	[93,234,145,110]	-2	hSpCas9	negative selection	7420956
17123591	17123614	10	-	27260156	MEWO	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	-0.0393364599499557	[438]	[337,390,457]	-1	hSpCas9	negative selection	7477934
17126754	17126777	10	+	27260156	MEWO	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.31322272074216007	[1106]	[1425,1300,1159]	6	hSpCas9	negative selection	7477935
17123577	17123600	10	+	27260156	MEWO	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.5991172266112089	[530]	[693,764,786]	9	hSpCas9	negative selection	7477936
17127828	17127851	10	-	27260156	MEWO	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.026704866289576135	[196]	[218,240,108]	0	hSpCas9	negative selection	7542205
17127887	17127910	10	-	27260156	MEWO	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.1539792222370182	[193]	[151,200,133]	-3	hSpCas9	negative selection	7542206
17126771	17126794	10	-	27260156	MEWO	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.1360027349132671	[136]	[143,162,115]	3	hSpCas9	negative selection	7542207
17123591	17123614	10	-	27260156	LNCAPCLONEFGC	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	-0.3045148800435794	[438]	[402,310,308,261]	-5	hSpCas9	negative selection	7599185
17126754	17126777	10	+	27260156	LNCAPCLONEFGC	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.5155216258603881	[1106]	[1450,1278,1602,1434]	7	hSpCas9	negative selection	7599186
17123577	17123600	10	+	27260156	LNCAPCLONEFGC	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.11201121177071555	[530]	[451,464,573,600]	1	hSpCas9	negative selection	7599187
17127828	17127851	10	-	27260156	LNCAPCLONEFGC	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.08983873523238972	[196]	[129,173,147,215]	-1	hSpCas9	negative selection	7663456
17127887	17127910	10	-	27260156	LNCAPCLONEFGC	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.09519849426979476	[193]	[185,125,201,242]	1	hSpCas9	negative selection	7663457
17126771	17126794	10	-	27260156	LNCAPCLONEFGC	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.3442015933079239	[136]	[135,128,208,165]	5	hSpCas9	negative selection	7663458
17123591	17123614	10	-	27260156	PANC0327	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.0036701334483798947	[438]	[661,242,346,352]	0	hSpCas9	negative selection	7720436
17126754	17126777	10	+	27260156	PANC0327	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.4583046025690978	[1106]	[1470,1216,1373,1368]	6	hSpCas9	negative selection	7720437
17123577	17123600	10	+	27260156	PANC0327	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.4995566125017914	[530]	[737,799,641,475]	7	hSpCas9	negative selection	7720438
17127828	17127851	10	-	27260156	PANC0327	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.2683898588472511	[196]	[230,137,88,130]	-4	hSpCas9	negative selection	7784707
17127887	17127910	10	-	27260156	PANC0327	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.6562494965299153	[193]	[247,243,323,271]	8	hSpCas9	negative selection	7784708
17126771	17126794	10	-	27260156	PANC0327	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	-0.2713512285398514	[136]	[106,37,154,111]	-4	hSpCas9	negative selection	7784709
17123591	17123614	10	-	27260156	NCIH2009	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	-0.024529956757354324	[438]	[793,699,349]	0	hSpCas9	negative selection	7841687
17126754	17126777	10	+	27260156	NCIH2009	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.7636604315615236	[1106]	[2971,1999,2980]	9	hSpCas9	negative selection	7841688
17123577	17123600	10	+	27260156	NCIH2009	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.29937900943352125	[530]	[1141,728,914]	4	hSpCas9	negative selection	7841689
17127828	17127851	10	-	27260156	NCIH2009	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.3494931371779416	[196]	[417,337,308]	5	hSpCas9	negative selection	7905958
17127887	17127910	10	-	27260156	NCIH2009	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.08641738723123438	[193]	[331,177,271]	-1	hSpCas9	negative selection	7905959
17126771	17126794	10	-	27260156	NCIH2009	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.08431120561732186	[136]	[249,133,234]	1	hSpCas9	negative selection	7905960
17123591	17123614	10	-	27260156	NCIH1373	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.350993509648263	[438]	[762,530,371,234]	3	hSpCas9	negative selection	7962938
17126754	17126777	10	+	27260156	NCIH1373	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	1.058166268726094	[1106]	[3754,2532,1908,606]	9	hSpCas9	negative selection	7962939
17123577	17123600	10	+	27260156	NCIH1373	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.7767326195657881	[530]	[1317,796,1019,264]	7	hSpCas9	negative selection	7962940
17127828	17127851	10	-	27260156	NCIH1373	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.2157737997753184	[196]	[140,316,285,66]	2	hSpCas9	negative selection	8027209
17127887	17127910	10	-	27260156	NCIH1373	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.05826171963412308	[193]	[245,126,163,83]	0	hSpCas9	negative selection	8027210
17126771	17126794	10	-	27260156	NCIH1373	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.8710169315133002	[136]	[372,319,215,57]	8	hSpCas9	negative selection	8027211
17123591	17123614	10	-	27260156	PATU8902	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.45956917275356407	[438]	[1120,411,911,893]	5	hSpCas9	negative selection	8084189
17126754	17126777	10	+	27260156	PATU8902	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.6392690602246138	[1106]	[3233,2751,1322,2566]	6	hSpCas9	negative selection	8084190
17123577	17123600	10	+	27260156	PATU8902	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.2530582537010724	[530]	[785,665,739,1428]	2	hSpCas9	negative selection	8084191
17127828	17127851	10	-	27260156	PATU8902	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.6482889494343876	[196]	[426,346,472,461]	6	hSpCas9	negative selection	8148460
17127887	17127910	10	-	27260156	PATU8902	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.39405455419207946	[193]	[275,68,193,293]	-4	hSpCas9	negative selection	8148461
17126771	17126794	10	-	27260156	PATU8902	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.6329724677931323	[136]	[172,542,206,281]	6	hSpCas9	negative selection	8148462
17123591	17123614	10	-	27260156	PANC1	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.2077928174051802	[438]	[464,547,439,322]	3	hSpCas9	negative selection	8205440
17126754	17126777	10	+	27260156	PANC1	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.35034472812705797	[1106]	[1484,1343,1208,868]	5	hSpCas9	negative selection	8205441
17123577	17123600	10	+	27260156	PANC1	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.5376738954677758	[530]	[500,662,722,740]	8	hSpCas9	negative selection	8205442
17127828	17127851	10	-	27260156	PANC1	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.5364610872366331	[196]	[39,193,115,129]	-7	hSpCas9	negative selection	8269711
17127887	17127910	10	-	27260156	PANC1	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.4152678438827545	[193]	[250,327,148,183]	6	hSpCas9	negative selection	8269712
17126771	17126794	10	-	27260156	PANC1	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	1.0215382473439298	[136]	[238,141,429,138]	9	hSpCas9	negative selection	8269713
17123591	17123614	10	-	27260156	PANC0813	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	-0.23979765286684251	[438]	[503,413,463,373]	-4	hSpCas9	negative selection	8326691
17126754	17126777	10	+	27260156	PANC0813	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.5758423436731033	[1106]	[2298,1864,1649,1965]	8	hSpCas9	negative selection	8326692
17123577	17123600	10	+	27260156	PANC0813	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.48240360986679776	[530]	[796,861,1021,800]	7	hSpCas9	negative selection	8326693
17127828	17127851	10	-	27260156	PANC0813	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.06520944178482901	[196]	[203,287,229,163]	-1	hSpCas9	negative selection	8390962
17127887	17127910	10	-	27260156	PANC0813	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.29435474319886235	[193]	[277,142,331,359]	5	hSpCas9	negative selection	8390963
17126771	17126794	10	-	27260156	PANC0813	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.2913750108810409	[136]	[160,155,261,204]	5	hSpCas9	negative selection	8390964
17123591	17123614	10	-	27260156	RDES	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.07131135154660931	[438]	[355,461,620,749]	1	hSpCas9	negative selection	8447942
17126754	17126777	10	+	27260156	RDES	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.5578499455029267	[1106]	[1580,1500,2236,2298]	8	hSpCas9	negative selection	8447943
17123577	17123600	10	+	27260156	RDES	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.2866489842006243	[530]	[676,671,958,664]	4	hSpCas9	negative selection	8447944
17127828	17127851	10	-	27260156	RDES	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.09508769051845944	[196]	[192,209,190,257]	-1	hSpCas9	negative selection	8512213
17127887	17127910	10	-	27260156	RDES	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.2625752251945408	[193]	[139,346,285,318]	4	hSpCas9	negative selection	8512214
17126771	17126794	10	-	27260156	RDES	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.13547565348819912	[136]	[230,100,173,173]	2	hSpCas9	negative selection	8512215
17123591	17123614	10	-	27260156	PC3	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	-0.07179158338881107	[438]	[277,297,990,344]	-2	hSpCas9	negative selection	8569193
17126754	17126777	10	+	27260156	PC3	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.18409229986547038	[1106]	[732,1162,1934,1581]	4	hSpCas9	negative selection	8569194
17123577	17123600	10	+	27260156	PC3	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.6144092931115142	[530]	[616,767,1124,847]	9	hSpCas9	negative selection	8569195
17127828	17127851	10	-	27260156	PC3	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.07109420723017057	[196]	[163,160,186,223]	-1	hSpCas9	negative selection	8633464
17127887	17127910	10	-	27260156	PC3	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.06435391005427671	[193]	[152,180,182,213]	-1	hSpCas9	negative selection	8633465
17126771	17126794	10	-	27260156	PC3	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	-0.043297262376592816	[136]	[64,190,136,154]	-1	hSpCas9	negative selection	8633466
17123591	17123614	10	-	27260156	PATU8988T	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	-0.4724229542005582	[438]	[181,398,325,325]	-6	hSpCas9	negative selection	8690444
17126754	17126777	10	+	27260156	PATU8988T	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.1957613727554568	[1106]	[995,1366,1101,1469]	3	hSpCas9	negative selection	8690445
17123577	17123600	10	+	27260156	PATU8988T	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.42101780550349266	[530]	[684,730,516,832]	7	hSpCas9	negative selection	8690446
17127828	17127851	10	-	27260156	PATU8988T	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.3517014630324785	[196]	[313,473,54,144]	6	hSpCas9	negative selection	8754715
17127887	17127910	10	-	27260156	PATU8988T	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.10035415256552538	[193]	[166,236,203,198]	1	hSpCas9	negative selection	8754716
17126771	17126794	10	-	27260156	PATU8988T	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.5544206054734888	[136]	[84,288,140,278]	8	hSpCas9	negative selection	8754717
17123591	17123614	10	-	27260156	T47D	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.044334114990353016	[438]	[589,602,471,435]	0	hSpCas9	negative selection	8811695
17126754	17126777	10	+	27260156	T47D	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.32662077688572566	[1106]	[1836,1520,1478,1643]	7	hSpCas9	negative selection	8811696
17123577	17123600	10	+	27260156	T47D	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.25053160498692495	[530]	[757,668,695,829]	5	hSpCas9	negative selection	8811697
17127828	17127851	10	-	27260156	T47D	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.27488286378205185	[196]	[261,208,307,338]	6	hSpCas9	negative selection	8875966
17127887	17127910	10	-	27260156	T47D	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.21446642923842707	[193]	[277,238,266,266]	4	hSpCas9	negative selection	8875967
17126771	17126794	10	-	27260156	T47D	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.2514115684711338	[136]	[183,195,175,203]	5	hSpCas9	negative selection	8875968
17123591	17123614	10	-	27260156	SU8686	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	-0.10866993110530544	[438]	[472,325,429,381]	-2	hSpCas9	negative selection	8932946
17126754	17126777	10	+	27260156	SU8686	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.6670427942410693	[1106]	[1670,1504,1641,2259]	9	hSpCas9	negative selection	8932947
17123577	17123600	10	+	27260156	SU8686	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.38820232177706315	[530]	[609,664,746,752]	6	hSpCas9	negative selection	8932948
17127828	17127851	10	-	27260156	SU8686	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.1770473988710317	[196]	[210,242,212,210]	3	hSpCas9	negative selection	8997217
17127887	17127910	10	-	27260156	SU8686	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.12928605263016046	[193]	[183,171,214,289]	2	hSpCas9	negative selection	8997218
17126771	17126794	10	-	27260156	SU8686	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.4192103018951474	[136]	[120,79,246,321]	7	hSpCas9	negative selection	8997219
17123591	17123614	10	-	27260156	SKES1	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.1235749054944133	[438]	[536,666,397,348]	2	hSpCas9	negative selection	9054197
17126754	17126777	10	+	27260156	SKES1	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.3576961069380564	[1106]	[1651,1528,1206,1317]	7	hSpCas9	negative selection	9054198
17123577	17123600	10	+	27260156	SKES1	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.1777223619399319	[530]	[508,723,548,609]	4	hSpCas9	negative selection	9054199
17127828	17127851	10	-	27260156	SKES1	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.09461222345472309	[196]	[171,259,152,159]	-2	hSpCas9	negative selection	9118468
17127887	17127910	10	-	27260156	SKES1	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.12937025475584818	[193]	[223,160,150,174]	-3	hSpCas9	negative selection	9118469
17126771	17126794	10	-	27260156	SKES1	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.29039605576711947	[136]	[182,179,162,146]	6	hSpCas9	negative selection	9118470
17123591	17123614	10	-	27260156	TOV112D	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.012447172816790308	[438]	[458,655,346,366]	0	hSpCas9	negative selection	9175448
17126754	17126777	10	+	27260156	TOV112D	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.47154165321004005	[1106]	[1380,1998,1284,1580]	8	hSpCas9	negative selection	9175449
17123577	17123600	10	+	27260156	TOV112D	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.4683615394790198	[530]	[941,885,747,428]	8	hSpCas9	negative selection	9175450
17127828	17127851	10	-	27260156	TOV112D	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	-0.19373516377847189	[196]	[201,160,138,186]	-4	hSpCas9	negative selection	9239719
17127887	17127910	10	-	27260156	TOV112D	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.15005446054119798	[193]	[171,228,131,179]	-3	hSpCas9	negative selection	9239720
17126771	17126794	10	-	27260156	TOV112D	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	-0.046335970184811615	[136]	[55,241,132,120]	-1	hSpCas9	negative selection	9239721
17123591	17123614	10	-	27260156	TC71	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	0.28519852535819074	[438]	[640,584,492,575]	7	hSpCas9	negative selection	9296699
17126754	17126777	10	+	27260156	TC71	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.25382782375418445	[1106]	[1282,1473,1418,1490]	6	hSpCas9	negative selection	9296700
17123577	17123600	10	+	27260156	TC71	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.44537031835302	[530]	[731,632,837,903]	8	hSpCas9	negative selection	9296701
17127828	17127851	10	-	27260156	TC71	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.020542188469702793	[196]	[146,241,193,279]	0	hSpCas9	negative selection	9360970
17127887	17127910	10	-	27260156	TC71	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	-0.11022320962683474	[193]	[231,133,221,179]	-3	hSpCas9	negative selection	9360971
17126771	17126794	10	-	27260156	TC71	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.4271984119689973	[136]	[185,176,288,130]	8	hSpCas9	negative selection	9360972
17123591	17123614	10	-	27260156	TC32	viability	TTTGTATCTGTCCCCCACAGTGG	CUBN	ENSG00000107611	-0.25075311459683947	[438]	[416,229,414,350]	-4	hSpCas9	negative selection	9417950
17126754	17126777	10	+	27260156	TC32	viability	GACCTACCTGCTGCAAGCCTTGG	CUBN	ENSG00000107611	0.40686004044074564	[1106]	[1268,993,1653,1746]	7	hSpCas9	negative selection	9417951
17123577	17123600	10	+	27260156	TC32	viability	AGATGACTCACCTTCCACTGTGG	CUBN	ENSG00000107611	0.2244581012734701	[530]	[457,425,964,591]	4	hSpCas9	negative selection	9417952
17127828	17127851	10	-	27260156	TC32	viability	AATCTATCAGCTTAATTCCAAGG	CUBN	ENSG00000107611	0.005945272498311782	[196]	[262,99,256,144]	0	hSpCas9	negative selection	9482221
17127887	17127910	10	-	27260156	TC32	viability	GAAGATATTATAGAGTTAAAAGG	CUBN	ENSG00000107611	0.42163321059035475	[193]	[233,247,238,237]	7	hSpCas9	negative selection	9482222
17126771	17126794	10	-	27260156	TC32	viability	GATCTTGAGAGAAAATTCCAAGG	CUBN	ENSG00000107611	0.3455275719920743	[136]	[148,156,227,122]	6	hSpCas9	negative selection	9482223
17105545	17105568	10	+	27869803	HPAFII	viability after 27 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.21174591751571148	[1030]	[792,489,NaN]	1	hSpCas9	negative selection	9537507
17110900	17110923	10	+	27869803	HPAFII	viability after 27 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.5661809186989328	[191]	[281,38,NaN]	4	hSpCas9	negative selection	9537508
17114077	17114100	10	+	27869803	HPAFII	viability after 27 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	0.7189569392389407	[157]	[139,133,NaN]	6	hSpCas9	negative selection	9537509
17115467	17115490	10	-	27869803	HPAFII	viability after 27 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-0.18583501353774395	[391]	[316,67,NaN]	-1	hSpCas9	negative selection	9537510
17129227	17129250	10	-	27869803	HPAFII	viability after 27 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.5205938143330526	[286]	[192,235,NaN]	4	hSpCas9	negative selection	9537511
17129689	17129712	10	-	27869803	HPAFII	viability after 27 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	-0.5318511642615936	[125]	[77,18,NaN]	-4	hSpCas9	negative selection	9537512
17105545	17105568	10	+	27869803	HPAFII	viability after 15 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	-0.020266352634514373	[1030]	[1337,939,NaN]	0	hSpCas9	negative selection	9619956
17110900	17110923	10	+	27869803	HPAFII	viability after 15 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	-0.08414456173729135	[191]	[444,38,NaN]	-1	hSpCas9	negative selection	9619957
17114077	17114100	10	+	27869803	HPAFII	viability after 15 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	0.23004750795152468	[157]	[155,225,NaN]	2	hSpCas9	negative selection	9619958
17115467	17115490	10	-	27869803	HPAFII	viability after 15 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-0.26906151021449937	[391]	[504,252,NaN]	-3	hSpCas9	negative selection	9619959
17129227	17129250	10	-	27869803	HPAFII	viability after 15 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.3096681782221515	[286]	[697,185,NaN]	3	hSpCas9	negative selection	9619960
17129689	17129712	10	-	27869803	HPAFII	viability after 15 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	-0.9842643995703305	[125]	[73,64,NaN]	-7	hSpCas9	negative selection	9619961
17105545	17105568	10	+	27869803	ASPC1	viability after 36 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.4219427701880507	[2460]	[800,1435,1157]	4	hSpCas9	negative selection	9702405
17110900	17110923	10	+	27869803	ASPC1	viability after 36 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	-1.0988649268164312	[581]	[229,41,40]	-8	hSpCas9	negative selection	9702406
17114077	17114100	10	+	27869803	ASPC1	viability after 36 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	1.0974706417183748	[406]	[473,310,175]	8	hSpCas9	negative selection	9702407
17115467	17115490	10	-	27869803	ASPC1	viability after 36 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	0.11643873580248482	[815]	[403,247,286]	1	hSpCas9	negative selection	9702408
17129227	17129250	10	-	27869803	ASPC1	viability after 36 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.3493755047496016	[812]	[492,166,419]	3	hSpCas9	negative selection	9702409
17129689	17129712	10	-	27869803	ASPC1	viability after 36 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.5640054823119743	[241]	[253,42,97]	5	hSpCas9	negative selection	9702410
17105545	17105568	10	+	27869803	PATU8988S	viability after 35 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.09383915423440925	[2121]	[724,1099,NaN]	1	hSpCas9	negative selection	9784854
17110900	17110923	10	+	27869803	PATU8988S	viability after 35 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.25666114373802323	[380]	[106,259,NaN]	3	hSpCas9	negative selection	9784855
17114077	17114100	10	+	27869803	PATU8988S	viability after 35 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	0.45834717328042235	[371]	[359,50,NaN]	5	hSpCas9	negative selection	9784856
17115467	17115490	10	-	27869803	PATU8988S	viability after 35 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	0.6784689532521654	[690]	[621,267,NaN]	7	hSpCas9	negative selection	9784857
17129227	17129250	10	-	27869803	PATU8988S	viability after 35 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.6125580331977041	[552]	[354,325,NaN]	6	hSpCas9	negative selection	9784858
17129689	17129712	10	-	27869803	PATU8988S	viability after 35 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.45501495141957876	[326]	[194,165,NaN]	5	hSpCas9	negative selection	9784859
17105545	17105568	10	+	27869803	PATU8988S	viability after 31 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.16283463626703165	[2121]	[721,1233,NaN]	2	hSpCas9	negative selection	9867303
17110900	17110923	10	+	27869803	PATU8988S	viability after 31 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	0.5507829098129977	[380]	[156,305,NaN]	6	hSpCas9	negative selection	9867304
17114077	17114100	10	+	27869803	PATU8988S	viability after 31 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	0.5054431952384758	[371]	[243,167,NaN]	6	hSpCas9	negative selection	9867305
17115467	17115490	10	-	27869803	PATU8988S	viability after 31 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	1.1175494446399052	[690]	[614,575,NaN]	9	hSpCas9	negative selection	9867306
17129227	17129250	10	-	27869803	PATU8988S	viability after 31 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.6189667673753011	[552]	[368,299,NaN]	7	hSpCas9	negative selection	9867307
17129689	17129712	10	-	27869803	PATU8988S	viability after 31 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	0.07211637329791876	[326]	[100,182,NaN]	0	hSpCas9	negative selection	9867308
17105545	17105568	10	+	27869803	HPAFII	viability after 35 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	0.32199352236315004	[1030]	[619,688,NaN]	2	hSpCas9	negative selection	9949752
17110900	17110923	10	+	27869803	HPAFII	viability after 35 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	1.085839387194805	[191]	[369,21,NaN]	7	hSpCas9	negative selection	9949753
17114077	17114100	10	+	27869803	HPAFII	viability after 35 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	0.12000542163821515	[157]	[53,123,NaN]	0	hSpCas9	negative selection	9949754
17115467	17115490	10	-	27869803	HPAFII	viability after 35 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-0.48613059406656156	[391]	[207,66,NaN]	-3	hSpCas9	negative selection	9949755
17129227	17129250	10	-	27869803	HPAFII	viability after 35 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.6614066882806844	[286]	[178,286,NaN]	4	hSpCas9	negative selection	9949756
17129689	17129712	10	-	27869803	HPAFII	viability after 35 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	-0.7925351672280555	[125]	[41,30,NaN]	-5	hSpCas9	negative selection	9949757
17105545	17105568	10	+	27869803	HPAFII	viability after 31 days	CCCGGGAGACACGTGCAGAGAGG	CUBN	ENSG00000107611	-0.04379245087929684	[1030]	[545,577,NaN]	0	hSpCas9	negative selection	10032201
17110900	17110923	10	+	27869803	HPAFII	viability after 31 days	CATTGAACCGAGGCAGCACCTGG	CUBN	ENSG00000107611	1.0025804010329833	[191]	[380,35,NaN]	7	hSpCas9	negative selection	10032202
17114077	17114100	10	+	27869803	HPAFII	viability after 31 days	ACAAGTGTGGAGCAAGGCCCGGG	CUBN	ENSG00000107611	0.5830121450721525	[157]	[61,209,NaN]	4	hSpCas9	negative selection	10032203
17115467	17115490	10	-	27869803	HPAFII	viability after 31 days	GCGAGAGCAAGCTGGAGAGGTGG	CUBN	ENSG00000107611	-0.3915997657629665	[391]	[227,101,NaN]	-3	hSpCas9	negative selection	10032204
17129227	17129250	10	-	27869803	HPAFII	viability after 31 days	CCTCGAATGGCTACAGAGAGAGG	CUBN	ENSG00000107611	0.798262446186714	[286]	[326,228,NaN]	6	hSpCas9	negative selection	10032205
17129689	17129712	10	-	27869803	HPAFII	viability after 31 days	GCTGAAGTAAATGGCGAAGCTGG	CUBN	ENSG00000107611	-0.1326814684014045	[125]	[97,27,NaN]	-1	hSpCas9	negative selection	10032206
17110954	17110977	10	+	28162770	P31FUJ	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.3165363865760563	[163]	[239]	3	hSpCas9	negative selection	10139823
17084443	17084466	10	-	28162770	P31FUJ	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.6053011678992433	[503]	[900]	7	hSpCas9	negative selection	10139824
16913885	16913908	10	-	28162770	P31FUJ	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	0.013049189746058176	[182]	[216]	0	hSpCas9	negative selection	10139825
16876963	16876986	10	+	28162770	P31FUJ	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	0.6202746195049246	[314]	[568]	7	hSpCas9	negative selection	10139826
16869805	16869828	10	+	28162770	P31FUJ	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	0.5491971433663314	[163]	[281]	6	hSpCas9	negative selection	10139827
17114157	17114180	10	-	28162770	P31FUJ	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	0.19930880822340646	[62]	[84]	2	hSpCas9	negative selection	10139828
17110919	17110942	10	+	28162770	P31FUJ	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	0.604468295547513	[74]	[133]	7	hSpCas9	negative selection	10139829
17104497	17104520	10	+	28162770	P31FUJ	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	0.7465761849695356	[457]	[902]	8	hSpCas9	negative selection	10139830
17085710	17085733	10	+	28162770	P31FUJ	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.5075145992514654	[773]	[1292]	6	hSpCas9	negative selection	10139831
17085674	17085697	10	+	28162770	P31FUJ	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	-0.14981283974334714	[151]	[160]	-1	hSpCas9	negative selection	10139832
17110954	17110977	10	+	28162770	TF1	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	NaN	[NaN]	[215]	1	hSpCas9	negative selection	10309189
17084443	17084466	10	-	28162770	TF1	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	NaN	[NaN]	[537]	1	hSpCas9	negative selection	10309190
16913885	16913908	10	-	28162770	TF1	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	NaN	[NaN]	[128]	1	hSpCas9	negative selection	10309191
16876963	16876986	10	+	28162770	TF1	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	NaN	[NaN]	[440]	1	hSpCas9	negative selection	10309192
16869805	16869828	10	+	28162770	TF1	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	NaN	[NaN]	[146]	1	hSpCas9	negative selection	10309193
17114157	17114180	10	-	28162770	TF1	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10309194
17110919	17110942	10	+	28162770	TF1	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	NaN	[NaN]	[88]	1	hSpCas9	negative selection	10309195
17104497	17104520	10	+	28162770	TF1	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	NaN	[NaN]	[288]	1	hSpCas9	negative selection	10309196
17085710	17085733	10	+	28162770	TF1	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	NaN	[NaN]	[528]	1	hSpCas9	negative selection	10309197
17085674	17085697	10	+	28162770	TF1	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10309198
17110954	17110977	10	+	28162770	SKM1	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	-0.547379317913	[61]	[74]	-4	hSpCas9	negative selection	10478555
17084443	17084466	10	-	28162770	SKM1	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.5197868192261998	[100]	[255]	5	hSpCas9	negative selection	10478556
16913885	16913908	10	-	28162770	SKM1	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	-0.42345232153173074	[65]	[86]	-3	hSpCas9	negative selection	10478557
16876963	16876986	10	+	28162770	SKM1	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	0.554374180887733	[103]	[269]	5	hSpCas9	negative selection	10478558
16869805	16869828	10	+	28162770	SKM1	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	-0.11990656370285155	[66]	[108]	-1	hSpCas9	negative selection	10478559
17114157	17114180	10	-	28162770	SKM1	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	1.3767781660924918	[21]	[100]	9	hSpCas9	negative selection	10478560
17110919	17110942	10	+	28162770	SKM1	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	-2.669998604576956	[17]	[4]	-9	hSpCas9	negative selection	10478561
17104497	17104520	10	+	28162770	SKM1	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	0.6569701070109368	[79]	[222]	6	hSpCas9	negative selection	10478562
17085710	17085733	10	+	28162770	SKM1	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.670278800189299	[149]	[421]	6	hSpCas9	negative selection	10478563
17085674	17085697	10	+	28162770	SKM1	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	0.25199888342177124	[37]	[79]	2	hSpCas9	negative selection	10478564
17110954	17110977	10	+	28162770	SKM1	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	-0.547379317913	[61]	[74]	-4	hSpCas9	negative selection	10647921
17084443	17084466	10	-	28162770	SKM1	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.5197868192261998	[100]	[255]	5	hSpCas9	negative selection	10647922
16913885	16913908	10	-	28162770	SKM1	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	-0.42345232153173074	[65]	[86]	-3	hSpCas9	negative selection	10647923
16876963	16876986	10	+	28162770	SKM1	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	0.554374180887733	[103]	[269]	5	hSpCas9	negative selection	10647924
16869805	16869828	10	+	28162770	SKM1	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	-0.11990656370285155	[66]	[108]	-1	hSpCas9	negative selection	10647925
17114157	17114180	10	-	28162770	SKM1	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	1.3767781660924918	[21]	[100]	9	hSpCas9	negative selection	10647926
17110919	17110942	10	+	28162770	SKM1	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	-2.669998604576956	[17]	[4]	-9	hSpCas9	negative selection	10647927
17104497	17104520	10	+	28162770	SKM1	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	0.6569701070109368	[79]	[222]	6	hSpCas9	negative selection	10647928
17085710	17085733	10	+	28162770	SKM1	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.670278800189299	[149]	[421]	6	hSpCas9	negative selection	10647929
17085674	17085697	10	+	28162770	SKM1	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	0.25199888342177124	[37]	[79]	2	hSpCas9	negative selection	10647930
17110954	17110977	10	+	28162770	PL21	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	-1.194139324622726	[183]	[34]	-7	hSpCas9	negative selection	10817287
17084443	17084466	10	-	28162770	PL21	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.08046938382670388	[401]	[184]	0	hSpCas9	negative selection	10817288
16913885	16913908	10	-	28162770	PL21	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	-0.0021685608037952664	[213]	[92]	0	hSpCas9	negative selection	10817289
16876963	16876986	10	+	28162770	PL21	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	0.7381386362398894	[280]	[203]	6	hSpCas9	negative selection	10817290
16869805	16869828	10	+	28162770	PL21	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	-0.01973720892834485	[190]	[81]	0	hSpCas9	negative selection	10817291
17114157	17114180	10	-	28162770	PL21	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	-0.45882346767561266	[59]	[18]	-3	hSpCas9	negative selection	10817292
17110919	17110942	10	+	28162770	PL21	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	-0.6743295034268209	[54]	[14]	-5	hSpCas9	negative selection	10817293
17104497	17104520	10	+	28162770	PL21	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	0.4514786866907391	[288]	[171]	4	hSpCas9	negative selection	10817294
17085710	17085733	10	+	28162770	PL21	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.1711397427667678	[401]	[196]	1	hSpCas9	negative selection	10817295
17085674	17085697	10	+	28162770	PL21	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	1.2001396144893202	[139]	[139]	8	hSpCas9	negative selection	10817296
17110954	17110977	10	+	28162770	P31FUJ	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.3165363865760563	[163]	[239]	3	hSpCas9	negative selection	10986653
17084443	17084466	10	-	28162770	P31FUJ	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.6053011678992433	[503]	[900]	7	hSpCas9	negative selection	10986654
16913885	16913908	10	-	28162770	P31FUJ	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	0.013049189746058176	[182]	[216]	0	hSpCas9	negative selection	10986655
16876963	16876986	10	+	28162770	P31FUJ	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	0.6202746195049246	[314]	[568]	7	hSpCas9	negative selection	10986656
16869805	16869828	10	+	28162770	P31FUJ	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	0.5491971433663314	[163]	[281]	6	hSpCas9	negative selection	10986657
17114157	17114180	10	-	28162770	P31FUJ	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	0.19930880822340646	[62]	[84]	2	hSpCas9	negative selection	10986658
17110919	17110942	10	+	28162770	P31FUJ	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	0.604468295547513	[74]	[133]	7	hSpCas9	negative selection	10986659
17104497	17104520	10	+	28162770	P31FUJ	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	0.7465761849695356	[457]	[902]	8	hSpCas9	negative selection	10986660
17085710	17085733	10	+	28162770	P31FUJ	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.5075145992514654	[773]	[1292]	6	hSpCas9	negative selection	10986661
17085674	17085697	10	+	28162770	P31FUJ	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	-0.14981283974334714	[151]	[160]	-1	hSpCas9	negative selection	10986662
17110954	17110977	10	+	28162770	OCIAML5	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.6090673430043009	[76]	[211]	5	hSpCas9	negative selection	11156019
17084443	17084466	10	-	28162770	OCIAML5	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.6408916155548616	[231]	[652]	5	hSpCas9	negative selection	11156020
16913885	16913908	10	-	28162770	OCIAML5	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	0.3841316499974814	[103]	[244]	3	hSpCas9	negative selection	11156021
16876963	16876986	10	+	28162770	OCIAML5	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	1.4155844630401668	[129]	[625]	9	hSpCas9	negative selection	11156022
16869805	16869828	10	+	28162770	OCIAML5	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	0.07889178470635153	[106]	[203]	0	hSpCas9	negative selection	11156023
17114157	17114180	10	-	28162770	OCIAML5	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	-0.38258128756277676	[25]	[35]	-3	hSpCas9	negative selection	11156024
17110919	17110942	10	+	28162770	OCIAML5	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	0.6249805906902715	[36]	[102]	5	hSpCas9	negative selection	11156025
17104497	17104520	10	+	28162770	OCIAML5	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	0.6311424310564262	[278]	[779]	5	hSpCas9	negative selection	11156026
17085710	17085733	10	+	28162770	OCIAML5	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.10439200244274205	[369]	[717]	0	hSpCas9	negative selection	11156027
17085674	17085697	10	+	28162770	OCIAML5	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	-1.33239553039456	[112]	[80]	-6	hSpCas9	negative selection	11156028
17110954	17110977	10	+	28162770	EOL1	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.2493111671560347	[304]	[190]	2	hSpCas9	negative selection	11325385
17084443	17084466	10	-	28162770	EOL1	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.5763881351099925	[554]	[435]	5	hSpCas9	negative selection	11325386
16913885	16913908	10	-	28162770	EOL1	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	1.072446466682848	[351]	[389]	8	hSpCas9	negative selection	11325387
16876963	16876986	10	+	28162770	EOL1	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	0.20942887970257718	[567]	[345]	2	hSpCas9	negative selection	11325388
16869805	16869828	10	+	28162770	EOL1	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	-0.31646032793326034	[337]	[142]	-2	hSpCas9	negative selection	11325389
17114157	17114180	10	-	28162770	EOL1	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	-0.2222936167587366	[92]	[41]	-2	hSpCas9	negative selection	11325390
17110919	17110942	10	+	28162770	EOL1	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	1.0207630868298376	[57]	[61]	8	hSpCas9	negative selection	11325391
17104497	17104520	10	+	28162770	EOL1	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	0.42296024033525687	[394]	[278]	4	hSpCas9	negative selection	11325392
17085710	17085733	10	+	28162770	EOL1	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.3940330548717548	[610]	[422]	3	hSpCas9	negative selection	11325393
17085674	17085697	10	+	28162770	EOL1	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	0.017657175962015992	[179]	[95]	0	hSpCas9	negative selection	11325394
17110954	17110977	10	+	28162770	MOLM13	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.15014908362065005	[257]	[206]	1	hSpCas9	negative selection	11494751
17084443	17084466	10	-	28162770	MOLM13	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	-0.28506973519905066	[513]	[304]	-2	hSpCas9	negative selection	11494752
16913885	16913908	10	-	28162770	MOLM13	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	-0.08504426498393947	[244]	[166]	0	hSpCas9	negative selection	11494753
16876963	16876986	10	+	28162770	MOLM13	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	0.3823713103585217	[416]	[392]	3	hSpCas9	negative selection	11494754
16869805	16869828	10	+	28162770	MOLM13	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	0.2916671416410569	[286]	[253]	2	hSpCas9	negative selection	11494755
17114157	17114180	10	-	28162770	MOLM13	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	-0.29604326022189653	[89]	[52]	-2	hSpCas9	negative selection	11494756
17110919	17110942	10	+	28162770	MOLM13	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	0.21205047711498892	[79]	[66]	1	hSpCas9	negative selection	11494757
17104497	17104520	10	+	28162770	MOLM13	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	0.06177496128735083	[590]	[445]	0	hSpCas9	negative selection	11494758
17085710	17085733	10	+	28162770	MOLM13	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.27176502623986165	[770]	[672]	2	hSpCas9	negative selection	11494759
17085674	17085697	10	+	28162770	MOLM13	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	-0.03461095898460442	[118]	[83]	0	hSpCas9	negative selection	11494760
17110954	17110977	10	+	28162770	HEL	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.3767571421162262	[195]	[162]	3	hSpCas9	negative selection	11664117
17084443	17084466	10	-	28162770	HEL	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.39762633416382565	[415]	[350]	3	hSpCas9	negative selection	11664118
16913885	16913908	10	-	28162770	HEL	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	-0.10758514502086822	[216]	[128]	-1	hSpCas9	negative selection	11664119
16876963	16876986	10	+	28162770	HEL	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	-0.3164422633915981	[452]	[232]	-2	hSpCas9	negative selection	11664120
16869805	16869828	10	+	28162770	HEL	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	-0.9166885766136618	[223]	[75]	-5	hSpCas9	negative selection	11664121
17114157	17114180	10	-	28162770	HEL	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	1.3885553437488287	[64]	[108]	9	hSpCas9	negative selection	11664122
17110919	17110942	10	+	28162770	HEL	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	1.033929589324833	[60]	[79]	8	hSpCas9	negative selection	11664123
17104497	17104520	10	+	28162770	HEL	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	0.05154437756768615	[463]	[307]	0	hSpCas9	negative selection	11664124
17085710	17085733	10	+	28162770	HEL	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.31371057683035364	[661]	[526]	2	hSpCas9	negative selection	11664125
17085674	17085697	10	+	28162770	HEL	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	-0.49970543301984827	[116]	[52]	-3	hSpCas9	negative selection	11664126
17110954	17110977	10	+	28162770	MV411	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.47240391578304974	[159]	[186]	4	hSpCas9	negative selection	11833483
17084443	17084466	10	-	28162770	MV411	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.7628255753940879	[353]	[505]	7	hSpCas9	negative selection	11833484
16913885	16913908	10	-	28162770	MV411	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	-0.3916807199852861	[189]	[121]	-3	hSpCas9	negative selection	11833485
16876963	16876986	10	+	28162770	MV411	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	-0.0016576640931446063	[308]	[259]	0	hSpCas9	negative selection	11833486
16869805	16869828	10	+	28162770	MV411	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	0.11208569788788914	[133]	[121]	1	hSpCas9	negative selection	11833487
17114157	17114180	10	-	28162770	MV411	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	-1.1606471878543014	[68]	[25]	-6	hSpCas9	negative selection	11833488
17110919	17110942	10	+	28162770	MV411	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	2.7351028501490164	[22]	[128]	9	hSpCas9	negative selection	11833489
17104497	17104520	10	+	28162770	MV411	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	-0.4878297559114054	[282]	[169]	-4	hSpCas9	negative selection	11833490
17085710	17085733	10	+	28162770	MV411	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.5327612278456797	[470]	[573]	5	hSpCas9	negative selection	11833491
17085674	17085697	10	+	28162770	MV411	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	-0.8594776531337367	[111]	[51]	-5	hSpCas9	negative selection	11833492
17110954	17110977	10	+	28162770	MONOMAC1	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	0.6204186649670205	[121]	[214]	6	hSpCas9	negative selection	12002849
17084443	17084466	10	-	28162770	MONOMAC1	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	-0.11457468686758077	[254]	[269]	-1	hSpCas9	negative selection	12002850
16913885	16913908	10	-	28162770	MONOMAC1	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	-0.3517594418581958	[117]	[105]	-3	hSpCas9	negative selection	12002851
16876963	16876986	10	+	28162770	MONOMAC1	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	-0.45249803318854664	[227]	[190]	-4	hSpCas9	negative selection	12002852
16869805	16869828	10	+	28162770	MONOMAC1	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	-0.20716106433326117	[142]	[141]	-2	hSpCas9	negative selection	12002853
17114157	17114180	10	-	28162770	MONOMAC1	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	-0.2476629201295215	[57]	[55]	-2	hSpCas9	negative selection	12002854
17110919	17110942	10	+	28162770	MONOMAC1	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	0.5034028710815386	[23]	[38]	5	hSpCas9	negative selection	12002855
17104497	17104520	10	+	28162770	MONOMAC1	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	1.395050088094984	[201]	[608]	9	hSpCas9	negative selection	12002856
17085710	17085733	10	+	28162770	MONOMAC1	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.41430106908590014	[270]	[413]	4	hSpCas9	negative selection	12002857
17085674	17085697	10	+	28162770	MONOMAC1	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	1.3157758679057672	[81]	[233]	9	hSpCas9	negative selection	12002858
17110954	17110977	10	+	28162770	OCIAML2	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	-0.0046553607380920015	[39]	[220]	0	hSpCas9	negative selection	12172215
17084443	17084466	10	-	28162770	OCIAML2	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.29285028743735964	[61]	[420]	3	hSpCas9	negative selection	12172216
16913885	16913908	10	-	28162770	OCIAML2	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	-1.2482374039057131	[35]	[83]	-7	hSpCas9	negative selection	12172217
16876963	16876986	10	+	28162770	OCIAML2	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	0.13720714173158144	[72]	[444]	1	hSpCas9	negative selection	12172218
16869805	16869828	10	+	28162770	OCIAML2	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	-0.7402368849994412	[43]	[145]	-5	hSpCas9	negative selection	12172219
17114157	17114180	10	-	28162770	OCIAML2	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	0.7344846046624512	[17]	[165]	7	hSpCas9	negative selection	12172220
17110919	17110942	10	+	28162770	OCIAML2	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	-1.0111982066048637	[11]	[32]	-6	hSpCas9	negative selection	12172221
17104497	17104520	10	+	28162770	OCIAML2	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	0.5872142493301231	[54]	[457]	6	hSpCas9	negative selection	12172222
17085710	17085733	10	+	28162770	OCIAML2	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.18281241336176146	[95]	[603]	1	hSpCas9	negative selection	12172223
17085674	17085697	10	+	28162770	OCIAML2	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	-0.6428108006248416	[19]	[70]	-5	hSpCas9	negative selection	12172224
17110954	17110977	10	+	28162770	OCIAML3	viability	GTATTCACACACTCAACGGGTGG	CUBN	ENSG00000107611	-0.27207954543680096	[41]	[104]	-2	hSpCas9	negative selection	12341581
17084443	17084466	10	-	28162770	OCIAML3	viability	TTAGCGGATCTGCGTTGTGGTGG	CUBN	ENSG00000107611	0.46931829504466593	[116]	[488]	4	hSpCas9	negative selection	12341582
16913885	16913908	10	-	28162770	OCIAML3	viability	GTGGAGAATCACTGCCCCGGAGG	CUBN	ENSG00000107611	0.25398926623078694	[34]	[125]	2	hSpCas9	negative selection	12341583
16876963	16876986	10	+	28162770	OCIAML3	viability	GAACCGGCCCAGCGATGGTGAGG	CUBN	ENSG00000107611	-0.27763907077870154	[103]	[258]	-2	hSpCas9	negative selection	12341584
16869805	16869828	10	+	28162770	OCIAML3	viability	GTAGTCATGGGAGCAGGAGGTGG	CUBN	ENSG00000107611	0.3620490120882397	[49]	[193]	3	hSpCas9	negative selection	12341585
17114157	17114180	10	-	28162770	OCIAML3	viability	GCTGCGTCTGTGATGCTGGGTGG	CUBN	ENSG00000107611	-1.371615218987715	[17]	[20]	-7	hSpCas9	negative selection	12341586
17110919	17110942	10	+	28162770	OCIAML3	viability	CTGGTGGACAGGCCTGGCAGTGG	CUBN	ENSG00000107611	0.9084927002050202	[14]	[84]	7	hSpCas9	negative selection	12341587
17104497	17104520	10	+	28162770	OCIAML3	viability	AAGTTCCTCCATTCAAACAGGGG	CUBN	ENSG00000107611	0.1284583841469279	[89]	[296]	1	hSpCas9	negative selection	12341588
17085710	17085733	10	+	28162770	OCIAML3	viability	GTGCAGAACTTCCCAAGAAGGGG	CUBN	ENSG00000107611	0.3792974930104167	[149]	[588]	3	hSpCas9	negative selection	12341589
17085674	17085697	10	+	28162770	OCIAML3	viability	GGGCCAGTAGTCTGGAGCGGTGG	CUBN	ENSG00000107611	-0.4729922393627974	[39]	[86]	-4	hSpCas9	negative selection	12341590