Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 4921
• Symbol: DDR2
• Description: discoidin domain receptor tyrosine kinase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/DDR2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
162759806	162759829	1	+	26472758	Jiyoye	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.6635151347656592	[143]	[171]	5	hSpCas9	negative selection	41976
162761360	162761383	1	+	26472758	Jiyoye	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	4.314065977114391	[0]	[14]	9	hSpCas9	negative selection	41977
162766034	162766057	1	-	26472758	Jiyoye	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	-0.724069151772379	[137]	[62]	-5	hSpCas9	negative selection	41978
162773468	162773491	1	+	26472758	Jiyoye	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	0.49508247065530075	[190]	[202]	4	hSpCas9	negative selection	41979
162776278	162776301	1	+	26472758	Jiyoye	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.3120181484655331	[140]	[131]	2	hSpCas9	negative selection	41980
162754793	162754816	1	+	26472758	Jiyoye	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	0.15116140334985217	[122]	[102]	1	hSpCas9	negative selection	41981
162754815	162754838	1	+	26472758	Jiyoye	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.7052567344388678	[243]	[299]	5	hSpCas9	negative selection	41982
162755207	162755230	1	-	26472758	Jiyoye	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	0.17397620521284274	[200]	[170]	1	hSpCas9	negative selection	41983
162755696	162755719	1	+	26472758	Jiyoye	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	-1.0581671996210362	[427]	[154]	-6	hSpCas9	negative selection	41984
162759882	162759905	1	+	26472758	Jiyoye	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.25245278670723137	[117]	[105]	2	hSpCas9	negative selection	41985
162759806	162759829	1	+	26472758	KBM7	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.3181613058092246	[675,492]	[313,360]	3	hSpCas9	negative selection	233094
162761360	162761383	1	+	26472758	KBM7	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	0.7964894051319842	[30,38]	[27,29]	8	hSpCas9	negative selection	233095
162766034	162766057	1	-	26472758	KBM7	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	0.7912571195206122	[431,324]	[379,237]	8	hSpCas9	negative selection	233096
162773468	162773491	1	+	26472758	KBM7	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	0.19556952832205088	[590,557]	[263,350]	2	hSpCas9	negative selection	233097
162776278	162776301	1	+	26472758	KBM7	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.245807828623624	[517,204]	[219,169]	2	hSpCas9	negative selection	233098
162754793	162754816	1	+	26472758	KBM7	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	-0.24784051288773612	[465,277]	[177,113]	-2	hSpCas9	negative selection	233099
162754815	162754838	1	+	26472758	KBM7	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.09923645331573017	[1056,1178]	[625,517]	1	hSpCas9	negative selection	233100
162755207	162755230	1	-	26472758	KBM7	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	0.10964149901582937	[545,553]	[193,357]	1	hSpCas9	negative selection	233101
162755696	162755719	1	+	26472758	KBM7	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	0.2744255758728198	[1470,982]	[554,804]	3	hSpCas9	negative selection	233102
162759882	162759905	1	+	26472758	KBM7	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.8405327897471695	[751,620]	[297,822]	8	hSpCas9	negative selection	233103
162759806	162759829	1	+	26472758	Raji	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.651852852076206	[276]	[100]	6	hSpCas9	negative selection	424212
162761360	162761383	1	+	26472758	Raji	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	-0.8926164646264008	[23]	[2]	-6	hSpCas9	negative selection	424213
162766034	162766057	1	-	26472758	Raji	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	-1.5141048413726705	[159]	[12]	-8	hSpCas9	negative selection	424214
162773468	162773491	1	+	26472758	Raji	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	0.6000419317749172	[198]	[69]	5	hSpCas9	negative selection	424215
162776278	162776301	1	+	26472758	Raji	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	-0.19927780286045227	[187]	[37]	-2	hSpCas9	negative selection	424216
162754793	162754816	1	+	26472758	Raji	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	1.6246014294589215	[108]	[77]	9	hSpCas9	negative selection	424217
162754815	162754838	1	+	26472758	Raji	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.35677703053800713	[672]	[199]	3	hSpCas9	negative selection	424218
162755207	162755230	1	-	26472758	Raji	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	0.1813841168173762	[227]	[59]	1	hSpCas9	negative selection	424219
162755696	162755719	1	+	26472758	Raji	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	-0.4844983792873473	[626]	[103]	-4	hSpCas9	negative selection	424220
162759882	162759905	1	+	26472758	Raji	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.3845306775335494	[372]	[112]	3	hSpCas9	negative selection	424221
162759806	162759829	1	+	26472758	K562	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.6363389873206373	[345]	[453]	5	hSpCas9	negative selection	615330
162761360	162761383	1	+	26472758	K562	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	-0.40765796891324646	[32]	[20]	-3	hSpCas9	negative selection	615331
162766034	162766057	1	-	26472758	K562	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	-0.9006316051368362	[459]	[207]	-5	hSpCas9	negative selection	615332
162773468	162773491	1	+	26472758	K562	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	0.21763374657839407	[597]	[586]	1	hSpCas9	negative selection	615333
162776278	162776301	1	+	26472758	K562	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.05609094483882948	[285]	[250]	0	hSpCas9	negative selection	615334
162754793	162754816	1	+	26472758	K562	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	0.34395440121736137	[321]	[344]	2	hSpCas9	negative selection	615335
162754815	162754838	1	+	26472758	K562	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	-0.03410092566476597	[842]	[694]	0	hSpCas9	negative selection	615336
162755207	162755230	1	-	26472758	K562	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	1.5332275479719448	[281]	[688]	9	hSpCas9	negative selection	615337
162755696	162755719	1	+	26472758	K562	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	-0.45767640665270715	[980]	[602]	-3	hSpCas9	negative selection	615338
162759882	162759905	1	+	26472758	K562	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.6064916688515807	[644]	[828]	5	hSpCas9	negative selection	615339
162719099	162719122	1	-	26627737	DLD1	viability	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	1.4253808432723212	[133]	[134,126,80]	9	hSpCas9	negative selection	767208
162753109	162753132	1	-	26627737	DLD1	viability	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.25676665669636733	[354]	[204,135,66]	2	hSpCas9	negative selection	767212
162754834	162754857	1	+	26627737	DLD1	viability	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	1.4209920227267834	[402]	[290,262,438]	9	hSpCas9	negative selection	767213
162755211	162755234	1	-	26627737	DLD1	viability	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.5812917777026321	[1129]	[475,641,479]	6	hSpCas9	negative selection	767214
162759820	162759843	1	+	26627737	DLD1	viability	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	1.807195188345795	[113]	[50,215,112]	9	hSpCas9	negative selection	767216
162761364	162761387	1	-	26627737	DLD1	viability	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.059626367388721624	[1219]	[406,538,186]	0	hSpCas9	negative selection	767217
162719099	162719122	1	-	26627737	GBM cells	viability after 5 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.032868331554549546	[184]	[94,107]	0	hSpCas9	negative selection	849523
162753109	162753132	1	-	26627737	GBM cells	viability after 5 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.285936997994933	[129]	[81,87]	4	hSpCas9	negative selection	849527
162754834	162754857	1	+	26627737	GBM cells	viability after 5 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.037133492325098494	[352]	[166,201]	0	hSpCas9	negative selection	849528
162755211	162755234	1	-	26627737	GBM cells	viability after 5 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.11958982363311188	[840]	[493,485]	2	hSpCas9	negative selection	849529
162759820	162759843	1	+	26627737	GBM cells	viability after 5 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	-0.0261240674330927	[74]	[34,43]	0	hSpCas9	negative selection	849531
162761364	162761387	1	-	26627737	GBM cells	viability after 5 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.04583626454885198	[332]	[212,132]	0	hSpCas9	negative selection	849532
162719099	162719122	1	-	26627737	GBM cells	viability after 13 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	-0.16143830311481333	[184]	[70,104]	-2	hSpCas9	negative selection	931838
162753109	162753132	1	-	26627737	GBM cells	viability after 13 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.18418753192861237	[129]	[87,40]	-2	hSpCas9	negative selection	931842
162754834	162754857	1	+	26627737	GBM cells	viability after 13 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.138823008594833	[352]	[238,187]	1	hSpCas9	negative selection	931843
162755211	162755234	1	-	26627737	GBM cells	viability after 13 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.08994923309451619	[840]	[574,412]	1	hSpCas9	negative selection	931844
162759820	162759843	1	+	26627737	GBM cells	viability after 13 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.8972984136918468	[74]	[77,73]	9	hSpCas9	negative selection	931846
162761364	162761387	1	-	26627737	GBM cells	viability after 13 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.42195340455351865	[332]	[130,137]	-5	hSpCas9	negative selection	931847
162719099	162719122	1	-	26627737	GBM cells	viability after 21 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.43796387874700066	[184]	[155,117]	4	hSpCas9	negative selection	1014153
162753109	162753132	1	-	26627737	GBM cells	viability after 21 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.41177205164021224	[129]	[94,92]	4	hSpCas9	negative selection	1014157
162754834	162754857	1	+	26627737	GBM cells	viability after 21 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.4133660722132095	[352]	[143,143]	-4	hSpCas9	negative selection	1014158
162755211	162755234	1	-	26627737	GBM cells	viability after 21 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.41188240761676087	[840]	[657,561]	4	hSpCas9	negative selection	1014159
162759820	162759843	1	+	26627737	GBM cells	viability after 21 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	-0.2705828788789493	[74]	[38,28]	-2	hSpCas9	negative selection	1014161
162761364	162761387	1	-	26627737	GBM cells	viability after 21 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.11438529653669638	[332]	[175,158]	-1	hSpCas9	negative selection	1014162
162719099	162719122	1	-	26627737	RPE1	viability after 9 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.08683927858405194	[373]	[81,178]	0	hSpCas9	negative selection	1096468
162753109	162753132	1	-	26627737	RPE1	viability after 9 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	1.5770757989374147	[202]	[93,312]	8	hSpCas9	negative selection	1096472
162754834	162754857	1	+	26627737	RPE1	viability after 9 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.4080853476237777	[1878]	[448,435]	-3	hSpCas9	negative selection	1096473
162755211	162755234	1	-	26627737	RPE1	viability after 9 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	1.0085986308044776	[1899]	[1022,1420]	6	hSpCas9	negative selection	1096474
162759820	162759843	1	+	26627737	RPE1	viability after 9 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.5185712315865257	[595]	[196,357]	3	hSpCas9	negative selection	1096476
162761364	162761387	1	-	26627737	RPE1	viability after 9 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.038422011879996165	[1279]	[270,543]	0	hSpCas9	negative selection	1096477
162719099	162719122	1	-	26627737	RPE1	viability after 12 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.3103772099221406	[373]	[42,210]	2	hSpCas9	negative selection	1178783
162753109	162753132	1	-	26627737	RPE1	viability after 12 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.945021012154084	[202]	[104,104]	6	hSpCas9	negative selection	1178787
162754834	162754857	1	+	26627737	RPE1	viability after 12 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.13137269969526022	[1878]	[507,410]	-1	hSpCas9	negative selection	1178788
162755211	162755234	1	-	26627737	RPE1	viability after 12 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	1.1768980864845515	[1899]	[1004,1311]	7	hSpCas9	negative selection	1178789
162759820	162759843	1	+	26627737	RPE1	viability after 12 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.6064972069438259	[595]	[185,304]	4	hSpCas9	negative selection	1178791
162761364	162761387	1	-	26627737	RPE1	viability after 12 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	0.5230511075754595	[1279]	[533,451]	3	hSpCas9	negative selection	1178792
162719099	162719122	1	-	26627737	RPE1	viability after 15 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.3140215960656545	[373]	[73,186]	2	hSpCas9	negative selection	1261098
162753109	162753132	1	-	26627737	RPE1	viability after 15 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	1.4556831454664088	[202]	[128,184]	7	hSpCas9	negative selection	1261102
162754834	162754857	1	+	26627737	RPE1	viability after 15 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.6726434942790078	[1878]	[363,303]	-4	hSpCas9	negative selection	1261103
162755211	162755234	1	-	26627737	RPE1	viability after 15 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	1.3370238112108708	[1899]	[1621,1102]	7	hSpCas9	negative selection	1261104
162759820	162759843	1	+	26627737	RPE1	viability after 15 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.6018023898959292	[595]	[122,383]	4	hSpCas9	negative selection	1261106
162761364	162761387	1	-	26627737	RPE1	viability after 15 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	0.2908141940049077	[1279]	[473,412]	2	hSpCas9	negative selection	1261107
162719099	162719122	1	-	26627737	RPE1	viability after 18 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	1.1122434884979513	[373]	[150,289]	6	hSpCas9	negative selection	1343413
162753109	162753132	1	-	26627737	RPE1	viability after 18 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	1.209027511710963	[202]	[130,121]	7	hSpCas9	negative selection	1343417
162754834	162754857	1	+	26627737	RPE1	viability after 18 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.4716521524694689	[1878]	[399,328]	-3	hSpCas9	negative selection	1343418
162755211	162755234	1	-	26627737	RPE1	viability after 18 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.9713609057012365	[1899]	[1029,978]	6	hSpCas9	negative selection	1343419
162759820	162759843	1	+	26627737	RPE1	viability after 18 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	1.1156028708333385	[595]	[319,378]	6	hSpCas9	negative selection	1343421
162761364	162761387	1	-	26627737	RPE1	viability after 18 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	0.256992947173589	[1279]	[391,434]	1	hSpCas9	negative selection	1343422
162719099	162719122	1	-	26627737	HeLa	viability after 8 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.39475294391610594	[128]	[114,19,93]	3	hSpCas9	negative selection	1425728
162753109	162753132	1	-	26627737	HeLa	viability after 8 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.0748004183793809	[285]	[169,108,88]	0	hSpCas9	negative selection	1425732
162754834	162754857	1	+	26627737	HeLa	viability after 8 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.24850279897810013	[929]	[442,342,263]	-2	hSpCas9	negative selection	1425733
162755211	162755234	1	-	26627737	HeLa	viability after 8 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.9502964948517445	[808]	[1010,667,450]	7	hSpCas9	negative selection	1425734
162759820	162759843	1	+	26627737	HeLa	viability after 8 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	1.139340519284666	[63]	[136,6,56]	8	hSpCas9	negative selection	1425736
162761364	162761387	1	-	26627737	HeLa	viability after 8 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	0.3100026204633411	[526]	[527,160,221]	3	hSpCas9	negative selection	1425737
162719099	162719122	1	-	26627737	HeLa	viability after 12 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	1.408024031781954	[128]	[47,166,203]	8	hSpCas9	negative selection	1508043
162753109	162753132	1	-	26627737	HeLa	viability after 12 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.2347022539577569	[285]	[93,167,31]	-2	hSpCas9	negative selection	1508047
162754834	162754857	1	+	26627737	HeLa	viability after 12 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.26539017124686337	[929]	[236,634,488]	2	hSpCas9	negative selection	1508048
162755211	162755234	1	-	26627737	HeLa	viability after 12 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.8328262535576698	[808]	[739,554,499]	6	hSpCas9	negative selection	1508049
162759820	162759843	1	+	26627737	HeLa	viability after 12 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	2.371999524398484	[63]	[147,146,114]	9	hSpCas9	negative selection	1508051
162761364	162761387	1	-	26627737	HeLa	viability after 12 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	0.16196508336159204	[526]	[263,135,342]	1	hSpCas9	negative selection	1508052
162719099	162719122	1	-	26627737	HeLa	viability after 15 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	2.029353892329104	[128]	[199,232,209]	9	hSpCas9	negative selection	1590358
162753109	162753132	1	-	26627737	HeLa	viability after 15 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.9033598802673257	[285]	[16,99,70]	-7	hSpCas9	negative selection	1590362
162754834	162754857	1	+	26627737	HeLa	viability after 15 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.1446155278629424	[929]	[217,360,458]	-1	hSpCas9	negative selection	1590363
162755211	162755234	1	-	26627737	HeLa	viability after 15 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	1.398646527712581	[808]	[705,876,1036]	8	hSpCas9	negative selection	1590364
162759820	162759843	1	+	26627737	HeLa	viability after 15 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	2.7395226853640233	[63]	[22,398,95]	9	hSpCas9	negative selection	1590366
162761364	162761387	1	-	26627737	HeLa	viability after 15 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	0.33859290994827024	[526]	[132,346,340]	3	hSpCas9	negative selection	1590367
162719099	162719122	1	-	26627737	HeLa	viability after 18 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	1.9716951456266043	[128]	[124,183,209]	9	hSpCas9	negative selection	1672673
162753109	162753132	1	-	26627737	HeLa	viability after 18 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.8570301598314565	[285]	[11,86,70]	-6	hSpCas9	negative selection	1672677
162754834	162754857	1	+	26627737	HeLa	viability after 18 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.12997461079094896	[929]	[152,298,458]	-1	hSpCas9	negative selection	1672678
162755211	162755234	1	-	26627737	HeLa	viability after 18 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	1.3950153343025051	[808]	[463,732,1036]	8	hSpCas9	negative selection	1672679
162759820	162759843	1	+	26627737	HeLa	viability after 18 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	2.7423417011462847	[63]	[13,332,95]	9	hSpCas9	negative selection	1672681
162761364	162761387	1	-	26627737	HeLa	viability after 18 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	0.34650330203792173	[526]	[89,289,340]	3	hSpCas9	negative selection	1672682
162719099	162719122	1	-	26627737	HCT116	viability after 6 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.16254612749002553	[662]	[28,164]	0	hSpCas9	negative selection	1754988
162753109	162753132	1	-	26627737	HCT116	viability after 6 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.32569164854717125	[487]	[12,141]	1	hSpCas9	negative selection	1754992
162754834	162754857	1	+	26627737	HCT116	viability after 6 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	1.2415939676587517	[711]	[89,360]	6	hSpCas9	negative selection	1754993
162755211	162755234	1	-	26627737	HCT116	viability after 6 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	1.4259238887397492	[1332]	[1059,288]	7	hSpCas9	negative selection	1754994
162759820	162759843	1	+	26627737	HCT116	viability after 6 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.953100869908361	[122]	[88,8]	5	hSpCas9	negative selection	1754996
162761364	162761387	1	-	26627737	HCT116	viability after 6 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	0.8009100084544039	[1023]	[594,106]	4	hSpCas9	negative selection	1754997
162719099	162719122	1	-	26627737	HCT116	viability after 8 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	1.0064215102360639	[128]	[107,112,205]	8	hSpCas9	negative selection	1837303
162753109	162753132	1	-	26627737	HCT116	viability after 8 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.11051357337292678	[220]	[121,57,157]	-1	hSpCas9	negative selection	1837307
162754834	162754857	1	+	26627737	HCT116	viability after 8 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.8848927553691252	[445]	[336,371,647]	7	hSpCas9	negative selection	1837308
162755211	162755234	1	-	26627737	HCT116	viability after 8 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.8302423402018864	[488]	[529,333,572]	7	hSpCas9	negative selection	1837309
162759820	162759843	1	+	26627737	HCT116	viability after 8 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.49591868099553005	[90]	[137,58,16]	5	hSpCas9	negative selection	1837311
162761364	162761387	1	-	26627737	HCT116	viability after 8 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.4138080581266401	[808]	[341,327,333]	-5	hSpCas9	negative selection	1837312
162719099	162719122	1	-	26627737	HCT116	viability after 9 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.6926321769210948	[662]	[365,222]	5	hSpCas9	negative selection	1919618
162753109	162753132	1	-	26627737	HCT116	viability after 9 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-1.5522063081566846	[487]	[25,58]	-8	hSpCas9	negative selection	1919622
162754834	162754857	1	+	26627737	HCT116	viability after 9 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.7345581566870242	[711]	[336,299]	5	hSpCas9	negative selection	1919623
162755211	162755234	1	-	26627737	HCT116	viability after 9 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.5783690365752865	[1332]	[588,485]	4	hSpCas9	negative selection	1919624
162759820	162759843	1	+	26627737	HCT116	viability after 9 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	-0.30251000618972634	[122]	[53,4]	-2	hSpCas9	negative selection	1919626
162761364	162761387	1	-	26627737	HCT116	viability after 9 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	0.9434392417304733	[1023]	[350,663]	6	hSpCas9	negative selection	1919627
162719099	162719122	1	-	26627737	HCT116	viability after 12 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.6260999615057066	[128]	[58,149,109]	6	hSpCas9	negative selection	2001933
162753109	162753132	1	-	26627737	HCT116	viability after 12 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.22024794013947085	[220]	[193,104,100]	2	hSpCas9	negative selection	2001937
162754834	162754857	1	+	26627737	HCT116	viability after 12 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.14389842732554814	[445]	[315,221,232]	1	hSpCas9	negative selection	2001938
162755211	162755234	1	-	26627737	HCT116	viability after 12 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.6006090454795041	[488]	[289,480,408]	5	hSpCas9	negative selection	2001939
162759820	162759843	1	+	26627737	HCT116	viability after 12 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.533441841106389	[90]	[127,48,24]	5	hSpCas9	negative selection	2001941
162761364	162761387	1	-	26627737	HCT116	viability after 12 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.4467411119280187	[808]	[335,324,272]	-5	hSpCas9	negative selection	2001942
162719099	162719122	1	-	26627737	HCT116	viability after 15 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.6121723742331339	[128]	[174,38,132]	5	hSpCas9	negative selection	2084248
162753109	162753132	1	-	26627737	HCT116	viability after 15 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.10094234389705226	[220]	[219,78,68]	-1	hSpCas9	negative selection	2084252
162754834	162754857	1	+	26627737	HCT116	viability after 15 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.5792452591448091	[445]	[477,410,271]	5	hSpCas9	negative selection	2084253
162755211	162755234	1	-	26627737	HCT116	viability after 15 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	1.0901216668445124	[488]	[784,568,463]	8	hSpCas9	negative selection	2084254
162759820	162759843	1	+	26627737	HCT116	viability after 15 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	1.2339517856254778	[90]	[156,99,115]	8	hSpCas9	negative selection	2084256
162761364	162761387	1	-	26627737	HCT116	viability after 15 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.3440093819483767	[808]	[460,309,338]	-4	hSpCas9	negative selection	2084257
162719099	162719122	1	-	26627737	HCT116	viability after 18 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.5294071216440159	[128]	[121,42,108]	4	hSpCas9	negative selection	2166563
162753109	162753132	1	-	26627737	HCT116	viability after 18 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.0767065929701039	[220]	[137,93,106]	0	hSpCas9	negative selection	2166567
162754834	162754857	1	+	26627737	HCT116	viability after 18 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.5146664648267779	[445]	[337,296,288]	4	hSpCas9	negative selection	2166568
162755211	162755234	1	-	26627737	HCT116	viability after 18 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.8867464065973785	[488]	[515,364,434]	7	hSpCas9	negative selection	2166569
162759820	162759843	1	+	26627737	HCT116	viability after 18 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.8920528389808425	[90]	[178,23,43]	7	hSpCas9	negative selection	2166571
162761364	162761387	1	-	26627737	HCT116	viability after 18 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.44437623693304706	[808]	[271,261,331]	-4	hSpCas9	negative selection	2166572
162719069	162719092	1	+	24336569	HL60	viability	CCTGATTCCCAGAATGCTCTTGG	DDR2	ENSG00000162733	1.9414727106482625	[38]	[316]	9	hSpCas9	negative selection	2260136
162719076	162719099	1	-	24336569	HL60	viability	AACAGCACCAAGAGCATTCTGGG	DDR2	ENSG00000162733	-0.2946114914140001	[1386]	[2392]	-3	hSpCas9	negative selection	2260137
162719099	162719122	1	-	24336569	HL60	viability	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.24117802299904423	[807]	[2020]	2	hSpCas9	negative selection	2260138
162753093	162753116	1	+	24336569	HL60	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	0.09383561272729163	[386]	[873]	0	hSpCas9	negative selection	2260139
162753102	162753125	1	-	24336569	HL60	viability	CTGACATGCCCAGAGGATAGCGG	DDR2	ENSG00000162733	0.47469590907390746	[741]	[2181]	4	hSpCas9	negative selection	2260140
162753109	162753132	1	-	24336569	HL60	viability	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.6574959374781791	[505]	[1688]	5	hSpCas9	negative selection	2260141
162753123	162753146	1	+	24336569	HL60	viability	AGGAGGCCAGATTCCAGATGAGG	DDR2	ENSG00000162733	0.3170306065784797	[909]	[2398]	3	hSpCas9	negative selection	2260142
162753129	162753152	1	-	24336569	HL60	viability	TGATGTCCTCATCTGGAATCTGG	DDR2	ENSG00000162733	0.17139009389461568	[876]	[2089]	1	hSpCas9	negative selection	2260143
162753136	162753159	1	-	24336569	HL60	viability	GAAGCTGTGATGTCCTCATCTGG	DDR2	ENSG00000162733	-0.578716363195928	[342]	[485]	-5	hSpCas9	negative selection	2260144
162753146	162753169	1	+	24336569	HL60	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.49015405820154156	[1592]	[4734]	4	hSpCas9	negative selection	2260145
162719069	162719092	1	+	24336569	KBM7	viability	CCTGATTCCCAGAATGCTCTTGG	DDR2	ENSG00000162733	0.026351991783529538	[62]	[174]	0	hSpCas9	negative selection	2327313
162719076	162719099	1	-	24336569	KBM7	viability	AACAGCACCAAGAGCATTCTGGG	DDR2	ENSG00000162733	0.2542262072443361	[730]	[2377]	2	hSpCas9	negative selection	2327314
162719099	162719122	1	-	24336569	KBM7	viability	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.36093965864235755	[707]	[2479]	3	hSpCas9	negative selection	2327315
162753093	162753116	1	+	24336569	KBM7	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	0.44279631227661925	[286]	[1063]	4	hSpCas9	negative selection	2327316
162753102	162753125	1	-	24336569	KBM7	viability	CTGACATGCCCAGAGGATAGCGG	DDR2	ENSG00000162733	-0.5623611950777381	[777]	[1436]	-4	hSpCas9	negative selection	2327317
162753109	162753132	1	-	24336569	KBM7	viability	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.04919777842007744	[623]	[1760]	0	hSpCas9	negative selection	2327318
162753123	162753146	1	+	24336569	KBM7	viability	AGGAGGCCAGATTCCAGATGAGG	DDR2	ENSG00000162733	0.6157941958936645	[745]	[3117]	5	hSpCas9	negative selection	2327319
162753129	162753152	1	-	24336569	KBM7	viability	TGATGTCCTCATCTGGAATCTGG	DDR2	ENSG00000162733	0.0754605709615559	[840]	[2416]	0	hSpCas9	negative selection	2327320
162753136	162753159	1	-	24336569	KBM7	viability	GAAGCTGTGATGTCCTCATCTGG	DDR2	ENSG00000162733	-0.08300676425302678	[79]	[205]	0	hSpCas9	negative selection	2327321
162753146	162753169	1	+	24336569	KBM7	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.4441462127526026	[1510]	[5606]	4	hSpCas9	negative selection	2327322
162632324	162632347	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATCAGAGCTGTTTTCTGTTTGG	DDR2	ENSG00000162733	-0.49161632403565125	[223,405]	[7,92]	-2	dCas9-VP64	positive selection	2439310
162632301	162632324	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGACTATTTCTTTTGACCCAAGG	DDR2	ENSG00000162733	-0.17697357520518953	[270,334]	[28,90]	0	dCas9-VP64	positive selection	2439311
162632285	162632308	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCTTTGCCCATAGTCCCTTGGG	DDR2	ENSG00000162733	-0.1575833252443557	[245,1043]	[42,219]	0	dCas9-VP64	positive selection	2439312
162650468	162650491	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCTCAGCTACTCAG	DDR2	ENSG00000162733	-0.32009396436001514	[73,465]	[65,28]	-1	dCas9-VP64	positive selection	2454583
162632324	162632347	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATCAGAGCTGTTTTCTGTTTGG	DDR2	ENSG00000162733	1.7999452691771314	[404,202]	[98,580]	8	dCas9-VP64	positive selection	2534565
162632301	162632324	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGACTATTTCTTTTGACCCAAGG	DDR2	ENSG00000162733	-0.8299468183560521	[536,430]	[95,81]	-7	dCas9-VP64	positive selection	2534566
162632285	162632308	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCTTTGCCCATAGTCCCTTGGG	DDR2	ENSG00000162733	-0.21767932894878483	[444,328]	[124,93]	-2	dCas9-VP64	positive selection	2534567
162650468	162650491	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCTCAGCTACTCAG	DDR2	ENSG00000162733	-0.35714226545986627	[161,80]	[51,10]	-4	dCas9-VP64	positive selection	2549838
162754716	162754739	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CACCAGAGTGATAAAATGGAGGG	DDR2	ENSG00000162733	0.19356807970524198	[4,4]	[4,4]	4	hSpCas9	positive selection	2982861
162755710	162755733	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATAAATGATGGAACCTCCAGGG	DDR2	ENSG00000162733	-0.1745793275158859	[3,2]	[3,0]	-3	hSpCas9	positive selection	2982862
162754816	162754839	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	-0.09659668460355753	[4,4]	[4,2]	-1	hSpCas9	positive selection	2982863
162753109	162753132	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.34512506900548157	[3,3]	[0,2]	-5	hSpCas9	positive selection	2982864
162754716	162754739	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CACCAGAGTGATAAAATGGAGGG	DDR2	ENSG00000162733	0.021415406528513037	[4,4]	[4,2]	0	hSpCas9	positive selection	3050719
162755710	162755733	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATAAATGATGGAACCTCCAGGG	DDR2	ENSG00000162733	-0.04218132320043712	[3,3]	[3,1]	0	hSpCas9	positive selection	3050720
162754816	162754839	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.1796143671007496	[4,4]	[3,2]	3	hSpCas9	positive selection	3050721
162753109	162753132	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.9406458690442431	[3,3]	[1,0]	-9	hSpCas9	positive selection	3050722
162753093	162753116		+	24336571	A375	resistance to PLX after 7 days	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.02777039749069435	[13,14]	[14,12]	0	hSpCas9	positive selection	3109110
162719114	162719137		+	24336571	A375	resistance to PLX after 7 days	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.4208363352859472	[9,10]	[15,11]	9	hSpCas9	positive selection	3109111
162719109	162719132		-	24336571	A375	resistance to PLX after 7 days	GCTTTTGCAGAACTCAAGATAGG	DDR2	ENSG00000162733	-0.08567915488480393	[4,5]	[3,4]	-3	hSpCas9	positive selection	3109112
162753093	162753116		+	24336571	A375	resistance to PLX after 14 days	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	1.3868708330527773	[12,9]	[12,15]	8	hSpCas9	positive selection	3166903
162719114	162719137		+	24336571	A375	resistance to PLX after 14 days	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.1548319159316895	[12,10]	[6,4]	1	hSpCas9	positive selection	3166904
162719109	162719132		-	24336571	A375	resistance to PLX after 14 days	GCTTTTGCAGAACTCAAGATAGG	DDR2	ENSG00000162733	-0.3221875779578447	[4,8]	[1,1]	-4	hSpCas9	positive selection	3166905
162753093	162753116		+	24336571	A375	viability after 7 days	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.09810413855715372	[15]	[13,14]	-1	hSpCas9	negative selection	3224696
162719114	162719137		+	24336571	A375	viability after 7 days	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.6064940655227606	[6]	[9,10]	8	hSpCas9	negative selection	3224697
162719109	162719132		-	24336571	A375	viability after 7 days	GCTTTTGCAGAACTCAAGATAGG	DDR2	ENSG00000162733	0.2886002431715604	[4]	[4,5]	4	hSpCas9	negative selection	3224698
162753093	162753116		+	24336571	A375	viability after 14 days	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.357661084370124	[15]	[12,9]	-4	hSpCas9	negative selection	3282489
162719114	162719137		+	24336571	A375	viability after 14 days	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.8297773036447864	[6]	[12,10]	9	hSpCas9	negative selection	3282490
162719109	162719132		-	24336571	A375	viability after 14 days	GCTTTTGCAGAACTCAAGATAGG	DDR2	ENSG00000162733	0.6707323072859379	[4]	[4,8]	8	hSpCas9	negative selection	3282491
162753093	162753116	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	2.7631699950493886	[27,16]	[0,0]	8	hSpCas9	positive selection	3345774
162754812	162754835	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	-0.6354298789234151	[261,212]	[0,0]	-4	hSpCas9	positive selection	3345775
162719114	162719137	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	-1.0978953151696587	[322,331]	[0,0]	-7	hSpCas9	positive selection	3345776
162754658	162754681	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	11.998107451953905	[235,235]	[6309,6309]	9	hSpCas9	positive selection	3364979
162719077	162719100	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.7027373597681978	[93,93]	[0,0]	3	hSpCas9	positive selection	3364980
162753146	162753169	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	-1.0094603292490663	[307,307]	[0,0]	-6	hSpCas9	positive selection	3364981
162754716	162754739	1	-	26780180	HT29	viability (Avana library 4 designs)	CACCAGAGTGATAAAATGGAGGG	DDR2	ENSG00000162733	0.162998459248946	[]	[]	0	hSpCas9	negative selection	3419565
162755710	162755733	1	-	26780180	HT29	viability (Avana library 4 designs)	GATAAATGATGGAACCTCCAGGG	DDR2	ENSG00000162733	0.940246619216527	[]	[]	3	hSpCas9	negative selection	3419566
162754815	162754838	1	+	26780180	HT29	viability (Avana library 4 designs)	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.817013236188353	[]	[]	3	hSpCas9	negative selection	3419567
162753109	162753132	1	-	26780180	HT29	viability (Avana library 4 designs)	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.499227282224549	[]	[]	1	hSpCas9	negative selection	3419568
162754815	162754838	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	1.73336155712236	[]	[]	2	hSpCas9	negative selection	3498802
162753109	162753132	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.472829502645731	[]	[]	0	hSpCas9	negative selection	3498803
162754716	162754739	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CACCAGAGTGATAAAATGGAGGG	DDR2	ENSG00000162733	0.299154708892947	[]	[]	0	hSpCas9	negative selection	3498804
162755710	162755733	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATAAATGATGGAACCTCCAGGG	DDR2	ENSG00000162733	-2.32277330330882	[]	[]	-3	hSpCas9	negative selection	3498805
162761360	162761383	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	3.98015598284137	[]	[]	6	hSpCas9	negative selection	3498806
162761317	162761340	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGACGTCATCCAGGACAAGGG	DDR2	ENSG00000162733	2.11204051513335	[]	[]	3	hSpCas9	negative selection	3498807
162754815	162754838	1	+	26780180	A375	viability (Avana lentiGuide)	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	1.7107014755833	[]	[]	2	hSpCas9	negative selection	3607461
162753109	162753132	1	-	26780180	A375	viability (Avana lentiGuide)	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	2.50924519063482	[]	[]	2	hSpCas9	negative selection	3607462
162754716	162754739	1	-	26780180	A375	viability (Avana lentiGuide)	CACCAGAGTGATAAAATGGAGGG	DDR2	ENSG00000162733	4.84610082946285	[]	[]	4	hSpCas9	negative selection	3607463
162755710	162755733	1	-	26780180	A375	viability (Avana lentiGuide)	GATAAATGATGGAACCTCCAGGG	DDR2	ENSG00000162733	8.08364040430439	[]	[]	6	hSpCas9	negative selection	3607464
162761360	162761383	1	+	26780180	A375	viability (Avana lentiGuide)	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	2.92461522742028	[]	[]	3	hSpCas9	negative selection	3607465
162761317	162761340	1	-	26780180	A375	viability (Avana lentiGuide)	GTTGACGTCATCCAGGACAAGGG	DDR2	ENSG00000162733	5.75267118574548	[]	[]	5	hSpCas9	negative selection	3607466
162754815	162754838	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	-0.255952022083382	[5]	[4,4]	-4	hSpCas9	positive selection	3716120
162753109	162753132	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.04870144758803774	[4]	[4,3]	-1	hSpCas9	positive selection	3716121
162754716	162754739	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACCAGAGTGATAAAATGGAGGG	DDR2	ENSG00000162733	-0.07704060615337902	[6]	[6,5]	-1	hSpCas9	positive selection	3716122
162755710	162755733	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATAAATGATGGAACCTCCAGGG	DDR2	ENSG00000162733	-0.2509218136603452	[5]	[5,3]	-4	hSpCas9	positive selection	3716123
162761360	162761383	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	0.2773035337598834	[4]	[5,5]	7	hSpCas9	positive selection	3716124
162761317	162761340	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGACGTCATCCAGGACAAGGG	DDR2	ENSG00000162733	0.05703811106119008	[4]	[5,4]	1	hSpCas9	positive selection	3716125
162754815	162754838	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.14645136703527611	[6]	[6,5]	3	hSpCas9	positive selection	3824727
162753109	162753132	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.43623079528318154	[5]	[3,2]	-5	hSpCas9	positive selection	3824728
162754716	162754739	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACCAGAGTGATAAAATGGAGGG	DDR2	ENSG00000162733	0.11070888166935347	[6]	[5,5]	2	hSpCas9	positive selection	3824729
162755710	162755733	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATAAATGATGGAACCTCCAGGG	DDR2	ENSG00000162733	-0.0024585718697046066	[4]	[4,3]	0	hSpCas9	positive selection	3824730
162761360	162761383	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	-0.3042789369958783	[5]	[4,2]	-4	hSpCas9	positive selection	3824731
162761317	162761340	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGACGTCATCCAGGACAAGGG	DDR2	ENSG00000162733	-0.5339245063516843	[4]	[1,3]	-6	hSpCas9	positive selection	3824732
162753146	162753169	1	+	26780180	A375	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	1.01577923859602	[]	[]	5	hSpCas9	negative selection	3932194
162753093	162753116	1	+	26780180	A375	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	0.907593355437821	[]	[]	4	hSpCas9	negative selection	3932195
162754812	162754835	1	+	26780180	A375	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.538884908692914	[]	[]	1	hSpCas9	negative selection	3932196
162719114	162719137	1	+	26780180	A375	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	1.46898375748181	[]	[]	8	hSpCas9	negative selection	3932197
162719077	162719100	1	-	26780180	A375	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.363485044386995	[]	[]	0	hSpCas9	negative selection	3932198
162754658	162754681	1	-	26780180	A375	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	1.21453687122898	[]	[]	6	hSpCas9	negative selection	3932199
162753146	162753169	1	+	26780180	HT29	viability (GeCKOv2 library)	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.266412425653183	[]	[]	0	hSpCas9	negative selection	4040160
162753093	162753116	1	+	26780180	HT29	viability (GeCKOv2 library)	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	0.896236876131807	[]	[]	4	hSpCas9	negative selection	4040161
162754812	162754835	1	+	26780180	HT29	viability (GeCKOv2 library)	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.18254342127082	[]	[]	0	hSpCas9	negative selection	4040162
162719114	162719137	1	+	26780180	HT29	viability (GeCKOv2 library)	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	1.39459201093535	[]	[]	7	hSpCas9	negative selection	4040163
162719077	162719100	1	-	26780180	HT29	viability (GeCKOv2 library)	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.334609460382041	[]	[]	0	hSpCas9	negative selection	4040164
162754658	162754681	1	-	26780180	HT29	viability (GeCKOv2 library)	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	1.76211024645549	[]	[]	8	hSpCas9	negative selection	4040165
162753093	162753116	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	0.38756815765488195	[3]	[1,3]	8	hSpCas9	positive selection	4131555
162719114	162719137	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	-0.07410537924958127	[3]	[1,2]	-2	hSpCas9	positive selection	4131556
162719109	162719132	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTTTTGCAGAACTCAAGATAGG	DDR2	ENSG00000162733	-0.33094594456301873	[1]	[0,0]	-7	hSpCas9	positive selection	4131557
162753093	162753116	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	0.2966649352683831	[3]	[0,3,4,0]	2	hSpCas9	positive selection	4195577
162719114	162719137	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.6616137792930996	[1]	[0,0,4,0]	4	hSpCas9	positive selection	4195578
162719109	162719132	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTTTTGCAGAACTCAAGATAGG	DDR2	ENSG00000162733	0.720699442636355	[1]	[1,1,1,0]	4	hSpCas9	positive selection	4195579
162753093	162753116	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.5268846275322779	[1]	[0,0]	-8	hSpCas9	positive selection	4266326
162754812	162754835	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	-0.010394177102131669	[3]	[3,1]	0	hSpCas9	positive selection	4266327
162719114	162719137	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.16279386655450057	[3]	[3,3]	3	hSpCas9	positive selection	4266328
162754658	162754681	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.10817858788113405	[3]	[2,2]	-2	hSpCas9	positive selection	4330599
162719077	162719100	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	-0.0056944899323237985	[1]	[1,0]	0	hSpCas9	positive selection	4330600
162753146	162753169	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.32951232862648255	[3]	[3,2]	6	hSpCas9	positive selection	4330601
162754835	162754857	1	+	27760321	OCIAML3	viability	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.0799770347595026	[447,368]	[247,450]	0	hSpCas9	negative selection	4393875
162759807	162759829	1	+	27760321	OCIAML3	viability	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.23656226499874347	[539,463]	[399,540]	2	hSpCas9	negative selection	4393876
162759868	162759890	1	-	27760321	OCIAML3	viability	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	-0.042137885137975784	[731,645]	[379,707]	0	hSpCas9	negative selection	4393877
162759940	162759962	1	+	27760321	OCIAML3	viability	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	0.4836470365164801	[547,526]	[560,624]	6	hSpCas9	negative selection	4393878
162761341	162761363	1	-	27760321	OCIAML3	viability	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	-0.4533747275659254	[878,732]	[365,578]	-4	hSpCas9	negative selection	4393879
162754835	162754857	1	+	27760321	OCIAML2	viability	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.08471191199195773	[447,368]	[285,341]	-1	hSpCas9	negative selection	4477338
162759807	162759829	1	+	27760321	OCIAML2	viability	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.7000874161132465	[539,463]	[621,704]	8	hSpCas9	negative selection	4477339
162759868	162759890	1	-	27760321	OCIAML2	viability	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	-0.10408219888943837	[731,645]	[363,719]	-1	hSpCas9	negative selection	4477340
162759940	162759962	1	+	27760321	OCIAML2	viability	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	0.7749060561204757	[547,526]	[686,821]	9	hSpCas9	negative selection	4477341
162761341	162761363	1	-	27760321	OCIAML2	viability	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	-0.07650940991475641	[878,732]	[522,737]	-1	hSpCas9	negative selection	4477342
162754835	162754857	1	+	27760321	MV411	viability	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.8187871418873327	[447,368]	[46,309]	-5	hSpCas9	negative selection	4560801
162759807	162759829	1	+	27760321	MV411	viability	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.7026646877261814	[539,463]	[495,599]	5	hSpCas9	negative selection	4560802
162759868	162759890	1	-	27760321	MV411	viability	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	0.5140380442007554	[731,645]	[281,1197]	3	hSpCas9	negative selection	4560803
162759940	162759962	1	+	27760321	MV411	viability	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	0.7122325864144503	[547,526]	[689,419]	5	hSpCas9	negative selection	4560804
162761341	162761363	1	-	27760321	MV411	viability	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	0.2676304971518084	[878,732]	[197,1297]	2	hSpCas9	negative selection	4560805
162754835	162754857	1	+	27760321	HL60	viability	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.2247869442179595	[447,368]	[425,347]	2	hSpCas9	negative selection	4644264
162759807	162759829	1	+	27760321	HL60	viability	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.252089793710656	[539,463]	[517,453]	3	hSpCas9	negative selection	4644265
162759868	162759890	1	-	27760321	HL60	viability	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	0.36107227619820403	[731,645]	[623,824]	4	hSpCas9	negative selection	4644266
162759940	162759962	1	+	27760321	HL60	viability	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	0.05519658331480176	[547,526]	[521,387]	0	hSpCas9	negative selection	4644267
162761341	162761363	1	-	27760321	HL60	viability	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	-0.6317139467676143	[878,732]	[428,416]	-6	hSpCas9	negative selection	4644268
162754835	162754857	1	+	27760321	HT1080	viability	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.7735782927361947	[368,287]	[301,137]	4	hSpCas9	negative selection	4727727
162759807	162759829	1	+	27760321	HT1080	viability	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	-0.6948073062096676	[463,361]	[72,132]	-3	hSpCas9	negative selection	4727728
162759868	162759890	1	-	27760321	HT1080	viability	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	0.3723444206669958	[645,503]	[264,330]	2	hSpCas9	negative selection	4727729
162759940	162759962	1	+	27760321	HT1080	viability	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	0.0541963915759649	[526,410]	[182,205]	0	hSpCas9	negative selection	4727730
162761341	162761363	1	-	27760321	HT1080	viability	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	-0.25561996595643866	[732,571]	[348,73]	-1	hSpCas9	negative selection	4727731
162754835	162754857	1	+	27760321	HT29	viability after 7 days	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.08373822247249513	[368,287]	[254,311,600]	-1	hSpCas9	negative selection	4811190
162759807	162759829	1	+	27760321	HT29	viability after 7 days	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	-0.08868364823309853	[463,361]	[473,435,580]	-1	hSpCas9	negative selection	4811191
162759868	162759890	1	-	27760321	HT29	viability after 7 days	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	0.22303038104897055	[645,503]	[1060,704,849]	3	hSpCas9	negative selection	4811192
162759940	162759962	1	+	27760321	HT29	viability after 7 days	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	-0.7038604982205847	[526,410]	[377,231,496]	-7	hSpCas9	negative selection	4811193
162761341	162761363	1	-	27760321	HT29	viability after 7 days	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	0.19349392547561362	[732,571]	[1086,822,983]	3	hSpCas9	negative selection	4811194
162754835	162754857	1	+	27760321	HT29	viability after 25 days	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.5087746386713268	[368,287]	[310,638,680]	5	hSpCas9	negative selection	4894653
162759807	162759829	1	+	27760321	HT29	viability after 25 days	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.46771182967020114	[463,361]	[746,552,650]	5	hSpCas9	negative selection	4894654
162759868	162759890	1	-	27760321	HT29	viability after 25 days	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	0.6953002494630521	[645,503]	[1081,1036,1070]	7	hSpCas9	negative selection	4894655
162759940	162759962	1	+	27760321	HT29	viability after 25 days	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	-0.19611238058553543	[526,410]	[507,400,493]	-2	hSpCas9	negative selection	4894656
162761341	162761363	1	-	27760321	HT29	viability after 25 days	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	0.5336053604316306	[732,571]	[1023,990,1241]	6	hSpCas9	negative selection	4894657
162754835	162754857	1	+	27760321	HT29	viability after 22 days	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.2771866364121439	[368,287]	[380,514,486]	3	hSpCas9	negative selection	4978116
162759807	162759829	1	+	27760321	HT29	viability after 22 days	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.666641729694162	[463,361]	[778,841,650]	7	hSpCas9	negative selection	4978117
162759868	162759890	1	-	27760321	HT29	viability after 22 days	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	0.32231942700459315	[645,503]	[918,734,836]	3	hSpCas9	negative selection	4978118
162759940	162759962	1	+	27760321	HT29	viability after 22 days	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	-0.18182497947217133	[526,410]	[623,319,485]	-2	hSpCas9	negative selection	4978119
162761341	162761363	1	-	27760321	HT29	viability after 22 days	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	0.3590628071311084	[732,571]	[851,1035,1017]	4	hSpCas9	negative selection	4978120
162754835	162754857	1	+	27760321	HT29	viability after 19 days	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.1800489010735793	[368,287]	[655,386,263]	1	hSpCas9	negative selection	5061579
162759807	162759829	1	+	27760321	HT29	viability after 19 days	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	-0.044898004331488495	[463,361]	[547,411,423]	0	hSpCas9	negative selection	5061580
162759868	162759890	1	-	27760321	HT29	viability after 19 days	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	0.4699627049346743	[645,503]	[1003,622,1106]	4	hSpCas9	negative selection	5061581
162759940	162759962	1	+	27760321	HT29	viability after 19 days	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	0.04169836553238854	[526,410]	[581,577,500]	0	hSpCas9	negative selection	5061582
162761341	162761363	1	-	27760321	HT29	viability after 19 days	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	0.7068984370131044	[732,571]	[1350,981,1329]	7	hSpCas9	negative selection	5061583
162754835	162754857	1	+	27760321	HT29	viability after 16 days	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.3453264702816967	[368,287]	[727,288,412]	4	hSpCas9	negative selection	5145042
162759807	162759829	1	+	27760321	HT29	viability after 16 days	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.4214415167573869	[463,361]	[891,662,325]	5	hSpCas9	negative selection	5145043
162759868	162759890	1	-	27760321	HT29	viability after 16 days	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	0.04888157509102731	[645,503]	[796,539,674]	0	hSpCas9	negative selection	5145044
162759940	162759962	1	+	27760321	HT29	viability after 16 days	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	0.1719060974371736	[526,410]	[746,357,688]	1	hSpCas9	negative selection	5145045
162761341	162761363	1	-	27760321	HT29	viability after 16 days	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	0.4432757137706609	[732,571]	[894,1045,1025]	5	hSpCas9	negative selection	5145046
162754835	162754857	1	+	27760321	HT29	viability after 13 days	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.09400435446835813	[368,287]	[446,449,327]	1	hSpCas9	negative selection	5228505
162759807	162759829	1	+	27760321	HT29	viability after 13 days	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.4971357634083196	[463,361]	[776,620,632]	6	hSpCas9	negative selection	5228506
162759868	162759890	1	-	27760321	HT29	viability after 13 days	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	0.1149582268582453	[645,503]	[832,581,749]	1	hSpCas9	negative selection	5228507
162759940	162759962	1	+	27760321	HT29	viability after 13 days	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	-0.31290242509816846	[526,410]	[490,320,497]	-4	hSpCas9	negative selection	5228508
162761341	162761363	1	-	27760321	HT29	viability after 13 days	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	-0.15382603205154732	[732,571]	[786,490,757]	-2	hSpCas9	negative selection	5228509
162754835	162754857	1	+	27760321	HT29	viability after 10 days	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.32570855795654985	[368,287]	[403,602,536]	4	hSpCas9	negative selection	5311968
162759807	162759829	1	+	27760321	HT29	viability after 10 days	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.17051386892010612	[463,361]	[518,749,478]	2	hSpCas9	negative selection	5311969
162759868	162759890	1	-	27760321	HT29	viability after 10 days	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	0.3535846307572398	[645,503]	[887,855,1003]	5	hSpCas9	negative selection	5311970
162759940	162759962	1	+	27760321	HT29	viability after 10 days	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	-0.6622228984682208	[526,410]	[337,364,405]	-6	hSpCas9	negative selection	5311971
162761341	162761363	1	-	27760321	HT29	viability after 10 days	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	0.3976912670839461	[732,571]	[970,1367,892]	5	hSpCas9	negative selection	5311972
162754835	162754857	1	+	27760321	MOLM13	viability	CGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.3395292656819403	[447,368]	[521,92]	2	hSpCas9	negative selection	5395431
162759807	162759829	1	+	27760321	MOLM13	viability	GGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	1.0272378026391213	[539,463]	[789,392]	7	hSpCas9	negative selection	5395432
162759868	162759890	1	-	27760321	MOLM13	viability	GTCATAGCCGGGCCACACGTGG	DDR2	ENSG00000162733	-0.080664595609242	[731,645]	[515,239]	0	hSpCas9	negative selection	5395433
162759940	162759962	1	+	27760321	MOLM13	viability	GTTTGAATTTGACCGCATCAGG	DDR2	ENSG00000162733	0.6662797495898071	[547,526]	[729,270]	4	hSpCas9	negative selection	5395434
162761341	162761363	1	-	27760321	MOLM13	viability	ACCGTGACAAACCGAGCACTGG	DDR2	ENSG00000162733	0.02066789096697874	[878,732]	[433,480]	0	hSpCas9	negative selection	5395435
162632818	162632841	1	+	27661255	K562	viability	GTCTGGATTTATGCTATGAAGGG	DDR2	ENSG00000162733	0.14056071126588737	[559,692]	[602,503]	5	dCas9-KRAB	negative selection	5474365
162632926	162632949	1	+	27661255	K562	viability	GCAGAGTTGAAATTGTTGGCAGG	DDR2	ENSG00000162733	-0.05024351161113738	[368,415]	[306,297]	-2	dCas9-KRAB	negative selection	5474366
162632421	162632444	1	-	27661255	K562	viability	GGATTCCTGGGAAAGCGCCAGGG	DDR2	ENSG00000162733	-0.023620355955827732	[888,843]	[788,589]	-1	dCas9-KRAB	negative selection	5474367
162632483	162632506	1	-	27661255	K562	viability	GGTGGTAGGCATACATCCACAGG	DDR2	ENSG00000162733	0.07265011736606064	[1199,1223]	[1155,899]	2	dCas9-KRAB	negative selection	5474368
162753093	162753116	1	+	27260156	BXPC3	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.3353091404454971	[137]	[61,57,133,225]	-6	hSpCas9	negative selection	5538786
162754812	162754835	1	+	27260156	BXPC3	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.25204738206803134	[664]	[772,928,768,834]	5	hSpCas9	negative selection	5538787
162719114	162719137	1	+	27260156	BXPC3	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.19052765869310884	[906]	[1084,1031,1154,1048]	4	hSpCas9	negative selection	5538788
162754658	162754681	1	-	27260156	BXPC3	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.01109357642409392	[689]	[621,727,784,736]	0	hSpCas9	negative selection	5603059
162719077	162719100	1	-	27260156	BXPC3	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.6152119511258001	[132]	[236,173,188,254]	9	hSpCas9	negative selection	5603060
162753146	162753169	1	+	27260156	BXPC3	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.488374787526373	[503]	[787,660,750,752]	9	hSpCas9	negative selection	5603061
162753093	162753116	1	+	27260156	A673	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.5850369013150902	[137]	[109,105,109,115]	-8	hSpCas9	negative selection	5660037
162754812	162754835	1	+	27260156	A673	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.22952373727033204	[664]	[1033,815,984,920]	5	hSpCas9	negative selection	5660038
162719114	162719137	1	+	27260156	A673	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.29074551892570155	[906]	[1332,1289,1386,1315]	6	hSpCas9	negative selection	5660039
162754658	162754681	1	-	27260156	A673	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.22972047678050822	[689]	[709,701,637,779]	-5	hSpCas9	negative selection	5724310
162719077	162719100	1	-	27260156	A673	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.44076481052371563	[132]	[318,109,191,262]	8	hSpCas9	negative selection	5724311
162753146	162753169	1	+	27260156	A673	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.27683984407327744	[503]	[743,717,691,781]	6	hSpCas9	negative selection	5724312
162753093	162753116	1	+	27260156	A375	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.8862536428297627	[137]	[31,90,58,157]	-8	hSpCas9	negative selection	5781288
162754812	162754835	1	+	27260156	A375	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.48150194631109544	[664]	[887,1175,1160,1115]	7	hSpCas9	negative selection	5781289
162719114	162719137	1	+	27260156	A375	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.4292111856658598	[906]	[1206,1742,1286,1496]	6	hSpCas9	negative selection	5781290
162754658	162754681	1	-	27260156	A375	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	0.02803763082985522	[689]	[969,979,767,613]	0	hSpCas9	negative selection	5845561
162719077	162719100	1	-	27260156	A375	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	1.0645086898795637	[132]	[396,323,310,272]	9	hSpCas9	negative selection	5845562
162753146	162753169	1	+	27260156	A375	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.6732816561490457	[503]	[845,1130,1079,743]	8	hSpCas9	negative selection	5845563
162753093	162753116	1	+	27260156	COLO741	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.8586759613188057	[137]	[94,66,126]	-9	hSpCas9	negative selection	5902539
162754812	162754835	1	+	27260156	COLO741	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.5047010011039533	[664]	[1304,1220,1103]	8	hSpCas9	negative selection	5902540
162719114	162719137	1	+	27260156	COLO741	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.3843845873836014	[906]	[1741,1317,1494]	7	hSpCas9	negative selection	5902541
162754658	162754681	1	-	27260156	COLO741	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	0.01901594281951957	[689]	[1053,893,753]	0	hSpCas9	negative selection	5966812
162719077	162719100	1	-	27260156	COLO741	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.5415383025954257	[132]	[219,240,275]	9	hSpCas9	negative selection	5966813
162753146	162753169	1	+	27260156	COLO741	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.3884374176183093	[503]	[946,1030,577]	7	hSpCas9	negative selection	5966814
162753093	162753116	1	+	27260156	CAL120	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.28858609753539355	[137]	[55,156,194]	-4	hSpCas9	negative selection	6023790
162754812	162754835	1	+	27260156	CAL120	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.6951808585141609	[664]	[1198,1641,1159]	8	hSpCas9	negative selection	6023791
162719114	162719137	1	+	27260156	CAL120	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.4207530119351286	[906]	[1480,1566,1479]	6	hSpCas9	negative selection	6023792
162754658	162754681	1	-	27260156	CAL120	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	0.13164752787913203	[689]	[635,876,1256]	2	hSpCas9	negative selection	6088063
162719077	162719100	1	-	27260156	CAL120	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.5263328229305091	[132]	[282,159,277]	7	hSpCas9	negative selection	6088064
162753146	162753169	1	+	27260156	CAL120	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.6106459638392027	[503]	[1293,661,966]	8	hSpCas9	negative selection	6088065
162753093	162753116	1	+	27260156	CADOES1	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.12925084675161336	[137]	[180,55,142,87]	-2	hSpCas9	negative selection	6145041
162754812	162754835	1	+	27260156	CADOES1	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.34789830994424076	[664]	[707,753,866,820]	6	hSpCas9	negative selection	6145042
162719114	162719137	1	+	27260156	CADOES1	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.15686923652196838	[906]	[925,798,1007,1031]	2	hSpCas9	negative selection	6145043
162754658	162754681	1	-	27260156	CADOES1	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	0.10026559921369216	[689]	[749,810,498,691]	1	hSpCas9	negative selection	6209314
162719077	162719100	1	-	27260156	CADOES1	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.9446590804295791	[132]	[144,243,339,222]	9	hSpCas9	negative selection	6209315
162753146	162753169	1	+	27260156	CADOES1	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.6275491136071961	[503]	[855,540,800,696]	8	hSpCas9	negative selection	6209316
162753093	162753116	1	+	27260156	EWS502	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.30989384253329577	[137]	[54,71,178,179]	-5	hSpCas9	negative selection	6266292
162754812	162754835	1	+	27260156	EWS502	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.6316856570570998	[664]	[1045,1157,1010,1151]	9	hSpCas9	negative selection	6266293
162719114	162719137	1	+	27260156	EWS502	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.32767779629370275	[906]	[897,1545,1048,1356]	6	hSpCas9	negative selection	6266294
162754658	162754681	1	-	27260156	EWS502	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.058820802470781364	[689]	[790,643,797,552]	-1	hSpCas9	negative selection	6330565
162719077	162719100	1	-	27260156	EWS502	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.6263492556962027	[132]	[129,179,307,267]	9	hSpCas9	negative selection	6330566
162753146	162753169	1	+	27260156	EWS502	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	1.0363479345925644	[503]	[1058,1337,1142,809]	9	hSpCas9	negative selection	6330567
162753093	162753116	1	+	27260156	EW8	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.3473570951395506	[137]	[77,78,64,131]	-6	hSpCas9	negative selection	6387543
162754812	162754835	1	+	27260156	EW8	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.42032164726894816	[664]	[846,727,552,796]	7	hSpCas9	negative selection	6387544
162719114	162719137	1	+	27260156	EW8	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.3776189155501899	[906]	[1269,1021,655,954]	7	hSpCas9	negative selection	6387545
162754658	162754681	1	-	27260156	EW8	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	0.008674408239125131	[689]	[673,635,374,607]	0	hSpCas9	negative selection	6451816
162719077	162719100	1	-	27260156	EW8	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.844068939414248	[132]	[245,207,141,191]	9	hSpCas9	negative selection	6451817
162753146	162753169	1	+	27260156	EW8	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.6676728901718709	[503]	[1110,576,528,447]	9	hSpCas9	negative selection	6451818
162753093	162753116	1	+	27260156	CORL105	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.35764809901944705	[137]	[196,63,119,125]	-6	hSpCas9	negative selection	6508794
162754812	162754835	1	+	27260156	CORL105	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.38944956770777894	[664]	[1046,1023,1096,923]	7	hSpCas9	negative selection	6508795
162719114	162719137	1	+	27260156	CORL105	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.3911454474949865	[906]	[1412,1240,1594,1355]	7	hSpCas9	negative selection	6508796
162754658	162754681	1	-	27260156	CORL105	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.13492202360560263	[689]	[852,548,855,710]	-3	hSpCas9	negative selection	6573067
162719077	162719100	1	-	27260156	CORL105	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.5167834494120387	[132]	[222,336,164,154]	8	hSpCas9	negative selection	6573068
162753146	162753169	1	+	27260156	CORL105	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.44801721321437493	[503]	[765,860,892,710]	7	hSpCas9	negative selection	6573069
162753093	162753116	1	+	27260156	HS294T	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.21079545266213562	[137]	[44,36,34,71]	-3	hSpCas9	negative selection	6630045
162754812	162754835	1	+	27260156	HS294T	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.6919130667631518	[664]	[423,235,286,778]	8	hSpCas9	negative selection	6630046
162719114	162719137	1	+	27260156	HS294T	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.42622691951439173	[906]	[347,639,402,503]	6	hSpCas9	negative selection	6630047
162754658	162754681	1	-	27260156	HS294T	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.1237620183660792	[689]	[174,334,218,254]	-2	hSpCas9	negative selection	6694318
162719077	162719100	1	-	27260156	HS294T	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.24183266349449584	[132]	[70,57,37,77]	3	hSpCas9	negative selection	6694319
162753146	162753169	1	+	27260156	HS294T	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.546831292869236	[503]	[292,260,247,345]	7	hSpCas9	negative selection	6694320
162753093	162753116	1	+	27260156	HCC44	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	0.21227658509176028	[137]	[277,146,144,159]	3	hSpCas9	negative selection	6751296
162754812	162754835	1	+	27260156	HCC44	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.31750544872330866	[664]	[834,649,1084,1218]	5	hSpCas9	negative selection	6751297
162719114	162719137	1	+	27260156	HCC44	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.5475077243544089	[906]	[1903,1291,1629,1255]	8	hSpCas9	negative selection	6751298
162754658	162754681	1	-	27260156	HCC44	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.312135740468321	[689]	[755,483,904,449]	-5	hSpCas9	negative selection	6815569
162719077	162719100	1	-	27260156	HCC44	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	1.1162520951210575	[132]	[300,268,532,242]	9	hSpCas9	negative selection	6815570
162753146	162753169	1	+	27260156	HCC44	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.5908374194569784	[503]	[700,690,1129,957]	8	hSpCas9	negative selection	6815571
162753093	162753116	1	+	27260156	G402	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.16196090814080555	[137]	[137,30,194,224]	-2	hSpCas9	negative selection	6872547
162754812	162754835	1	+	27260156	G402	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.4896290417592638	[664]	[1115,784,1066,1540]	6	hSpCas9	negative selection	6872548
162719114	162719137	1	+	27260156	G402	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.4285232383800226	[906]	[1306,1044,1613,1912]	5	hSpCas9	negative selection	6872549
162754658	162754681	1	-	27260156	G402	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.39573874091766187	[689]	[647,669,596,644]	-5	hSpCas9	negative selection	6936820
162719077	162719100	1	-	27260156	G402	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.40614189027527314	[132]	[144,67,439,188]	5	hSpCas9	negative selection	6936821
162753146	162753169	1	+	27260156	G402	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	1.1995801415509213	[503]	[1251,2515,1007,932]	9	hSpCas9	negative selection	6936822
162753093	162753116	1	+	27260156	L33	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.1319361550362277	[137]	[190,49,78,63]	-3	hSpCas9	negative selection	6993798
162754812	162754835	1	+	27260156	L33	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.34184220852027736	[664]	[807,412,471,804]	7	hSpCas9	negative selection	6993799
162719114	162719137	1	+	27260156	L33	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.3882632460640365	[906]	[1072,449,847,1230]	7	hSpCas9	negative selection	6993800
162754658	162754681	1	-	27260156	L33	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.23920572164216714	[689]	[650,236,269,675]	-5	hSpCas9	negative selection	7058071
162719077	162719100	1	-	27260156	L33	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.5155697780280879	[132]	[196,82,105,191]	8	hSpCas9	negative selection	7058072
162753146	162753169	1	+	27260156	L33	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.34163518589183467	[503]	[476,281,309,896]	7	hSpCas9	negative selection	7058073
162753093	162753116	1	+	27260156	K562	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.4018617137000846	[137]	[233,51,2,90]	-5	hSpCas9	negative selection	7115049
162754812	162754835	1	+	27260156	K562	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.5648631799026395	[664]	[1070,973,896,599]	7	hSpCas9	negative selection	7115050
162719114	162719137	1	+	27260156	K562	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.35787641703769557	[906]	[1248,866,626,1349]	4	hSpCas9	negative selection	7115051
162754658	162754681	1	-	27260156	K562	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	0.21767006468684613	[689]	[773,925,897,310]	2	hSpCas9	negative selection	7179322
162719077	162719100	1	-	27260156	K562	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.40493176876021897	[132]	[138,158,25,283]	5	hSpCas9	negative selection	7179323
162753146	162753169	1	+	27260156	K562	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.6372067025043652	[503]	[518,695,758,780]	7	hSpCas9	negative selection	7179324
162753093	162753116	1	+	27260156	HT29	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.6128207687367708	[137]	[99,108,71,150]	-7	hSpCas9	negative selection	7236300
162754812	162754835	1	+	27260156	HT29	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.12597364567047042	[664]	[1027,715,972,810]	2	hSpCas9	negative selection	7236301
162719114	162719137	1	+	27260156	HT29	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.32788804832664487	[906]	[1508,1422,1612,1036]	6	hSpCas9	negative selection	7236302
162754658	162754681	1	-	27260156	HT29	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	0.06734595525255982	[689]	[919,901,820,871]	1	hSpCas9	negative selection	7300573
162719077	162719100	1	-	27260156	HT29	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.4926415209636834	[132]	[213,143,304,235]	8	hSpCas9	negative selection	7300574
162753146	162753169	1	+	27260156	HT29	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.4508013791847586	[503]	[937,682,897,820]	8	hSpCas9	negative selection	7300575
162753093	162753116	1	+	27260156	MHHES1	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	0.15551134147904855	[137]	[202,298,64,143]	3	hSpCas9	negative selection	7357551
162754812	162754835	1	+	27260156	MHHES1	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.12871879793031404	[664]	[630,1074,890,692]	2	hSpCas9	negative selection	7357552
162719114	162719137	1	+	27260156	MHHES1	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.11599350444675482	[906]	[1541,979,987,964]	2	hSpCas9	negative selection	7357553
162754658	162754681	1	-	27260156	MHHES1	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.21416863079386012	[689]	[667,712,698,603]	-4	hSpCas9	negative selection	7421824
162719077	162719100	1	-	27260156	MHHES1	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.8545246974639163	[132]	[272,269,403,157]	9	hSpCas9	negative selection	7421825
162753146	162753169	1	+	27260156	MHHES1	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.5942493544549622	[503]	[675,1157,908,708]	8	hSpCas9	negative selection	7421826
162753093	162753116	1	+	27260156	MEWO	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.2914174756421959	[137]	[138,94,88]	-6	hSpCas9	negative selection	7478802
162754812	162754835	1	+	27260156	MEWO	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.47142067731577597	[664]	[982,844,782]	8	hSpCas9	negative selection	7478803
162719114	162719137	1	+	27260156	MEWO	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.3171148196680258	[906]	[1497,780,978]	6	hSpCas9	negative selection	7478804
162754658	162754681	1	-	27260156	MEWO	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.4050327985547927	[689]	[739,358,412]	-7	hSpCas9	negative selection	7543075
162719077	162719100	1	-	27260156	MEWO	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.7520657060516254	[132]	[303,197,144]	9	hSpCas9	negative selection	7543076
162753146	162753169	1	+	27260156	MEWO	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.3318550425785462	[503]	[549,565,655]	7	hSpCas9	negative selection	7543077
162753093	162753116	1	+	27260156	LNCAPCLONEFGC	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.5967861318043433	[137]	[64,31,127,115]	-7	hSpCas9	negative selection	7600053
162754812	162754835	1	+	27260156	LNCAPCLONEFGC	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.7756782909200995	[664]	[1035,945,1111,1047]	9	hSpCas9	negative selection	7600054
162719114	162719137	1	+	27260156	LNCAPCLONEFGC	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.3405484434758663	[906]	[1019,721,1200,1262]	5	hSpCas9	negative selection	7600055
162754658	162754681	1	-	27260156	LNCAPCLONEFGC	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.013223273817660752	[689]	[663,560,720,548]	0	hSpCas9	negative selection	7664326
162719077	162719100	1	-	27260156	LNCAPCLONEFGC	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.8671238637145817	[132]	[202,172,237,270]	9	hSpCas9	negative selection	7664327
162753146	162753169	1	+	27260156	LNCAPCLONEFGC	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.678624560670809	[503]	[718,650,999,597]	9	hSpCas9	negative selection	7664328
162753093	162753116	1	+	27260156	PANC0327	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	0.40256331843673454	[137]	[216,89,202,151]	6	hSpCas9	negative selection	7721304
162754812	162754835	1	+	27260156	PANC0327	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.5451722198534324	[664]	[899,590,1035,958]	7	hSpCas9	negative selection	7721305
162719114	162719137	1	+	27260156	PANC0327	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.26085553011305507	[906]	[908,690,1063,1227]	4	hSpCas9	negative selection	7721306
162754658	162754681	1	-	27260156	PANC0327	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.04560911239676846	[689]	[631,489,705,563]	0	hSpCas9	negative selection	7785577
162719077	162719100	1	-	27260156	PANC0327	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.7351797453651041	[132]	[168,137,262,221]	9	hSpCas9	negative selection	7785578
162753146	162753169	1	+	27260156	PANC0327	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	-0.1537513503576583	[503]	[537,377,398,308]	-2	hSpCas9	negative selection	7785579
162753093	162753116	1	+	27260156	NCIH2009	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.11831654369775912	[137]	[111,210,195]	-2	hSpCas9	negative selection	7842555
162754812	162754835	1	+	27260156	NCIH2009	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.4113629890817667	[664]	[1415,1319,1002]	5	hSpCas9	negative selection	7842556
162719114	162719137	1	+	27260156	NCIH2009	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.4806908510200578	[906]	[1864,1657,1799]	6	hSpCas9	negative selection	7842557
162754658	162754681	1	-	27260156	NCIH2009	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.4585167252165919	[689]	[783,579,757]	-5	hSpCas9	negative selection	7906828
162719077	162719100	1	-	27260156	NCIH2009	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	1.044731959506259	[132]	[447,557,152]	9	hSpCas9	negative selection	7906829
162753146	162753169	1	+	27260156	NCIH2009	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.49438097892678723	[503]	[1268,825,936]	6	hSpCas9	negative selection	7906830
162753093	162753116	1	+	27260156	NCIH1373	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.5176034789869326	[137]	[37,203,121,10]	-5	hSpCas9	negative selection	7963806
162754812	162754835	1	+	27260156	NCIH1373	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.9330103504063513	[664]	[1682,944,1635,397]	8	hSpCas9	negative selection	7963807
162719114	162719137	1	+	27260156	NCIH1373	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.8618161656843373	[906]	[1990,1747,2136,396]	8	hSpCas9	negative selection	7963808
162754658	162754681	1	-	27260156	NCIH1373	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	0.030089849966192128	[689]	[1065,530,923,182]	0	hSpCas9	negative selection	8028079
162719077	162719100	1	-	27260156	NCIH1373	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.7713237155968669	[132]	[177,256,151,112]	7	hSpCas9	negative selection	8028080
162753146	162753169	1	+	27260156	NCIH1373	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.9334261526188588	[503]	[1624,806,1198,202]	8	hSpCas9	negative selection	8028081
162753093	162753116	1	+	27260156	PATU8902	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-1.7887676709915188	[137]	[22,11,91,89]	-8	hSpCas9	negative selection	8085057
162754812	162754835	1	+	27260156	PATU8902	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.43953169936196856	[664]	[1419,1399,656,1749]	4	hSpCas9	negative selection	8085058
162719114	162719137	1	+	27260156	PATU8902	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.5576349489387746	[906]	[1455,2765,1665,1555]	6	hSpCas9	negative selection	8085059
162754658	162754681	1	-	27260156	PATU8902	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	0.4995213399105637	[689]	[1532,1453,1051,1475]	5	hSpCas9	negative selection	8149330
162719077	162719100	1	-	27260156	PATU8902	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	1.1328440684931185	[132]	[202,232,460,753]	9	hSpCas9	negative selection	8149331
162753146	162753169	1	+	27260156	PATU8902	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.5814725895002162	[503]	[1442,729,882,1190]	6	hSpCas9	negative selection	8149332
162753093	162753116	1	+	27260156	PANC1	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	0.34910046940870765	[137]	[31,314,280,30]	5	hSpCas9	negative selection	8206308
162754812	162754835	1	+	27260156	PANC1	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.5607443496834282	[664]	[1051,921,673,735]	8	hSpCas9	negative selection	8206309
162719114	162719137	1	+	27260156	PANC1	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.5433666657210283	[906]	[820,1153,1435,1125]	8	hSpCas9	negative selection	8206310
162754658	162754681	1	-	27260156	PANC1	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	0.07661301648417584	[689]	[600,638,569,673]	1	hSpCas9	negative selection	8270581
162719077	162719100	1	-	27260156	PANC1	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.8188072440268599	[132]	[255,326,147,110]	9	hSpCas9	negative selection	8270582
162753146	162753169	1	+	27260156	PANC1	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.5673053913440292	[503]	[497,772,544,749]	8	hSpCas9	negative selection	8270583
162753093	162753116	1	+	27260156	PANC0813	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.0637839560369895	[137]	[117,189,193,116]	-1	hSpCas9	negative selection	8327559
162754812	162754835	1	+	27260156	PANC0813	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.3356390319281284	[664]	[1152,964,1003,842]	5	hSpCas9	negative selection	8327560
162719114	162719137	1	+	27260156	PANC0813	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.34763218097118687	[906]	[1614,1295,1285,1252]	5	hSpCas9	negative selection	8327561
162754658	162754681	1	-	27260156	PANC0813	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.02476365641430578	[689]	[856,651,926,757]	0	hSpCas9	negative selection	8391832
162719077	162719100	1	-	27260156	PANC0813	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.23503687363227344	[132]	[187,217,190,140]	4	hSpCas9	negative selection	8391833
162753146	162753169	1	+	27260156	PANC0813	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.4951989557774342	[503]	[1045,846,781,688]	7	hSpCas9	negative selection	8391834
162753093	162753116	1	+	27260156	RDES	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.5021784746148819	[137]	[78,112,108,157]	-7	hSpCas9	negative selection	8448810
162754812	162754835	1	+	27260156	RDES	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.4577501789836481	[664]	[880,1041,1150,1150]	7	hSpCas9	negative selection	8448811
162719114	162719137	1	+	27260156	RDES	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.37511396067014013	[906]	[1164,1190,1566,1538]	6	hSpCas9	negative selection	8448812
162754658	162754681	1	-	27260156	RDES	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.00920867207904097	[689]	[672,951,700,810]	0	hSpCas9	negative selection	8513083
162719077	162719100	1	-	27260156	RDES	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.6917434491834842	[132]	[156,256,273,324]	9	hSpCas9	negative selection	8513084
162753146	162753169	1	+	27260156	RDES	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.36574568599792684	[503]	[704,678,742,869]	6	hSpCas9	negative selection	8513085
162753093	162753116	1	+	27260156	PC3	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	0.12474952390619465	[137]	[136,86,144,220]	3	hSpCas9	negative selection	8570061
162754812	162754835	1	+	27260156	PC3	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.16261139845208694	[664]	[492,539,1309,898]	3	hSpCas9	negative selection	8570062
162719114	162719137	1	+	27260156	PC3	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.1726434889893942	[906]	[720,774,1836,1100]	4	hSpCas9	negative selection	8570063
162754658	162754681	1	-	27260156	PC3	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.16424920406913285	[689]	[346,600,1160,622]	-4	hSpCas9	negative selection	8634334
162719077	162719100	1	-	27260156	PC3	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.6119382479703113	[132]	[163,192,277,196]	9	hSpCas9	negative selection	8634335
162753146	162753169	1	+	27260156	PC3	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.4079064891414682	[503]	[511,550,1198,605]	8	hSpCas9	negative selection	8634336
162753093	162753116	1	+	27260156	PATU8988T	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.648003460868865	[137]	[61,108,62,110]	-7	hSpCas9	negative selection	8691312
162754812	162754835	1	+	27260156	PATU8988T	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.528969520321234	[664]	[734,1228,816,959]	8	hSpCas9	negative selection	8691313
162719114	162719137	1	+	27260156	PATU8988T	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.4960461032649186	[906]	[1341,1076,1367,1131]	8	hSpCas9	negative selection	8691314
162754658	162754681	1	-	27260156	PATU8988T	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.11283508568812672	[689]	[689,677,564,532]	-2	hSpCas9	negative selection	8755585
162719077	162719100	1	-	27260156	PATU8988T	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.18882390107121605	[132]	[114,194,71,214]	3	hSpCas9	negative selection	8755586
162753146	162753169	1	+	27260156	PATU8988T	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.5073804796071664	[503]	[655,684,799,619]	8	hSpCas9	negative selection	8755587
162753093	162753116	1	+	27260156	T47D	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.35661221159660084	[137]	[92,135,101,171]	-6	hSpCas9	negative selection	8812563
162754812	162754835	1	+	27260156	T47D	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.2892963986046255	[664]	[944,890,875,1084]	6	hSpCas9	negative selection	8812564
162719114	162719137	1	+	27260156	T47D	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.2711143906397411	[906]	[1143,1115,1421,1433]	6	hSpCas9	negative selection	8812565
162754658	162754681	1	-	27260156	T47D	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.05596261772492184	[689]	[785,659,799,858]	-1	hSpCas9	negative selection	8876836
162719077	162719100	1	-	27260156	T47D	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.3520175247757924	[132]	[208,164,170,250]	7	hSpCas9	negative selection	8876837
162753146	162753169	1	+	27260156	T47D	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.3892760903219454	[503]	[778,852,609,830]	7	hSpCas9	negative selection	8876838
162753093	162753116	1	+	27260156	SU8686	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	0.028865846570905518	[137]	[60,198,103,203]	0	hSpCas9	negative selection	8933814
162754812	162754835	1	+	27260156	SU8686	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.6488917483813877	[664]	[1029,892,1053,1195]	9	hSpCas9	negative selection	8933815
162719114	162719137	1	+	27260156	SU8686	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.45568953457141936	[906]	[1207,1185,1131,1436]	7	hSpCas9	negative selection	8933816
162754658	162754681	1	-	27260156	SU8686	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.14045929513837602	[689]	[453,509,724,864]	-2	hSpCas9	negative selection	8998087
162719077	162719100	1	-	27260156	SU8686	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.8909536233284485	[132]	[216,185,203,404]	9	hSpCas9	negative selection	8998088
162753146	162753169	1	+	27260156	SU8686	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.6209718979090756	[503]	[749,641,670,1069]	9	hSpCas9	negative selection	8998089
162753093	162753116	1	+	27260156	SKES1	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.038229890586059634	[137]	[196,157,84,109]	-1	hSpCas9	negative selection	9055065
162754812	162754835	1	+	27260156	SKES1	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.47384644517605645	[664]	[984,1073,816,837]	8	hSpCas9	negative selection	9055066
162719114	162719137	1	+	27260156	SKES1	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.208497589057685	[906]	[1089,1171,1061,886]	4	hSpCas9	negative selection	9055067
162754658	162754681	1	-	27260156	SKES1	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.2567005439582969	[689]	[570,772,542,449]	-5	hSpCas9	negative selection	9119338
162719077	162719100	1	-	27260156	SKES1	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.3692285041589116	[132]	[243,153,171,126]	7	hSpCas9	negative selection	9119339
162753146	162753169	1	+	27260156	SKES1	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.3094364327647078	[503]	[661,652,667,522]	6	hSpCas9	negative selection	9119340
162753093	162753116	1	+	27260156	TOV112D	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.29702903541042414	[137]	[111,92,128,110]	-5	hSpCas9	negative selection	9176316
162754812	162754835	1	+	27260156	TOV112D	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.3807994911397643	[664]	[791,800,955,894]	7	hSpCas9	negative selection	9176317
162719114	162719137	1	+	27260156	TOV112D	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.14490111791103488	[906]	[1150,974,999,897]	3	hSpCas9	negative selection	9176318
162754658	162754681	1	-	27260156	TOV112D	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.12343588465075384	[689]	[893,759,542,398]	-2	hSpCas9	negative selection	9240589
162719077	162719100	1	-	27260156	TOV112D	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.8081948749373526	[132]	[128,219,317,252]	9	hSpCas9	negative selection	9240590
162753146	162753169	1	+	27260156	TOV112D	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.5126695993649717	[503]	[787,659,579,838]	8	hSpCas9	negative selection	9240591
162753093	162753116	1	+	27260156	TC71	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.41963746067978436	[137]	[154,66,122,94]	-8	hSpCas9	negative selection	9297567
162754812	162754835	1	+	27260156	TC71	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	0.37541978804216203	[664]	[923,849,891,1040]	8	hSpCas9	negative selection	9297568
162719114	162719137	1	+	27260156	TC71	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.2696086994807372	[906]	[1175,1241,1102,1168]	6	hSpCas9	negative selection	9297569
162754658	162754681	1	-	27260156	TC71	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.20146147813136223	[689]	[605,550,655,767]	-5	hSpCas9	negative selection	9361840
162719077	162719100	1	-	27260156	TC71	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.2730055060454888	[132]	[196,174,158,156]	6	hSpCas9	negative selection	9361841
162753146	162753169	1	+	27260156	TC71	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.4174511444400393	[503]	[735,629,719,804]	8	hSpCas9	negative selection	9361842
162753093	162753116	1	+	27260156	TC32	viability	AGCTATATGCCGCTATCCTCTGG	DDR2	ENSG00000162733	-0.8333649846038278	[137]	[63,66,83,76]	-9	hSpCas9	negative selection	9418818
162754812	162754835	1	+	27260156	TC32	viability	ATGGCACTCGCTGGATCTCTTGG	DDR2	ENSG00000162733	-0.22109956312144619	[664]	[561,298,826,564]	-4	hSpCas9	negative selection	9418819
162719114	162719137	1	+	27260156	TC32	viability	CTTGAGTTCTGCAAAAGCTCAGG	DDR2	ENSG00000162733	0.3481008928645659	[906]	[1118,820,1235,1226]	6	hSpCas9	negative selection	9418820
162754658	162754681	1	-	27260156	TC32	viability	TCAGGTTCCACTGGAATCTCAGG	DDR2	ENSG00000162733	-0.2896072064067177	[689]	[382,356,620,849]	-5	hSpCas9	negative selection	9483091
162719077	162719100	1	-	27260156	TC32	viability	GAACAGCACCAAGAGCATTCTGG	DDR2	ENSG00000162733	0.23131759831201748	[132]	[134,112,167,181]	4	hSpCas9	negative selection	9483092
162753146	162753169	1	+	27260156	TC32	viability	ACATCACAGCTTCCAGTCAGTGG	DDR2	ENSG00000162733	0.7109731962168312	[503]	[679,632,948,894]	9	hSpCas9	negative selection	9483093
162719099	162719122	1	-	27869803	HPAFII	viability after 27 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	-0.4436505602537352	[229]	[59,112,NaN]	-3	hSpCas9	negative selection	9530185
162753109	162753132	1	-	27869803	HPAFII	viability after 27 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.9699533985637785	[182]	[344,57,NaN]	7	hSpCas9	negative selection	9530189
162754834	162754857	1	+	27869803	HPAFII	viability after 27 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.3787879103401355	[409]	[378,197,NaN]	3	hSpCas9	negative selection	9530190
162755211	162755234	1	-	27869803	HPAFII	viability after 27 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.3606203714339611	[723]	[389,570,NaN]	3	hSpCas9	negative selection	9530191
162759820	162759843	1	+	27869803	HPAFII	viability after 27 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.8058730195326373	[108]	[127,76,NaN]	6	hSpCas9	negative selection	9530193
162761364	162761387	1	-	27869803	HPAFII	viability after 27 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.4687411204069556	[368]	[161,121,NaN]	-3	hSpCas9	negative selection	9530194
162719099	162719122	1	-	27869803	HPAFII	viability after 15 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	-0.006090080355067265	[229]	[210,267,NaN]	0	hSpCas9	negative selection	9612634
162753109	162753132	1	-	27869803	HPAFII	viability after 15 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.7927872555333932	[182]	[595,181,NaN]	8	hSpCas9	negative selection	9612638
162754834	162754857	1	+	27869803	HPAFII	viability after 15 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.4050820413171148	[409]	[884,395,NaN]	4	hSpCas9	negative selection	9612639
162755211	162755234	1	-	27869803	HPAFII	viability after 15 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.3458286965536215	[723]	[1282,805,NaN]	4	hSpCas9	negative selection	9612640
162759820	162759843	1	+	27869803	HPAFII	viability after 15 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.16256745617489754	[108]	[148,119,NaN]	1	hSpCas9	negative selection	9612642
162761364	162761387	1	-	27869803	HPAFII	viability after 15 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	0.03997412486372165	[368]	[588,294,NaN]	0	hSpCas9	negative selection	9612643
162719099	162719122	1	-	27869803	ASPC1	viability after 36 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	1.0061429616104443	[360]	[59,121,489]	8	hSpCas9	negative selection	9695083
162753109	162753132	1	-	27869803	ASPC1	viability after 36 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	1.7102283927005608	[419]	[367,926,197]	9	hSpCas9	negative selection	9695087
162754834	162754857	1	+	27869803	ASPC1	viability after 36 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.21050138690179665	[946]	[702,245,261]	2	hSpCas9	negative selection	9695088
162755211	162755234	1	-	27869803	ASPC1	viability after 36 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.07746364174339315	[1812]	[355,811,764]	0	hSpCas9	negative selection	9695089
162759820	162759843	1	+	27869803	ASPC1	viability after 36 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	1.3884946706449908	[140]	[173,173,59]	9	hSpCas9	negative selection	9695091
162761364	162761387	1	-	27869803	ASPC1	viability after 36 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	0.48475473911999856	[970]	[767,354,357]	5	hSpCas9	negative selection	9695092
162719099	162719122	1	-	27869803	PATU8988S	viability after 35 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	-0.030920701606341416	[291]	[162,66,NaN]	0	hSpCas9	negative selection	9777532
162753109	162753132	1	-	27869803	PATU8988S	viability after 35 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.37819270295580854	[419]	[194,64,NaN]	-4	hSpCas9	negative selection	9777536
162754834	162754857	1	+	27869803	PATU8988S	viability after 35 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.10178397740882472	[1103]	[537,415,NaN]	1	hSpCas9	negative selection	9777537
162755211	162755234	1	-	27869803	PATU8988S	viability after 35 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.339621719190246	[1376]	[827,574,NaN]	4	hSpCas9	negative selection	9777538
162759820	162759843	1	+	27869803	PATU8988S	viability after 35 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.009436187770918147	[184]	[73,75,NaN]	0	hSpCas9	negative selection	9777540
162761364	162761387	1	-	27869803	PATU8988S	viability after 35 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.36559011059367674	[963]	[231,370,NaN]	-4	hSpCas9	negative selection	9777541
162719099	162719122	1	-	27869803	PATU8988S	viability after 31 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.4592657362043751	[291]	[145,177,NaN]	5	hSpCas9	negative selection	9859981
162753109	162753132	1	-	27869803	PATU8988S	viability after 31 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	-0.2876225797370877	[419]	[145,125,NaN]	-3	hSpCas9	negative selection	9859985
162754834	162754857	1	+	27869803	PATU8988S	viability after 31 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	-0.046104121071116166	[1103]	[461,380,NaN]	0	hSpCas9	negative selection	9859986
162755211	162755234	1	-	27869803	PATU8988S	viability after 31 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.07297026434492793	[1376]	[555,604,NaN]	0	hSpCas9	negative selection	9859987
162759820	162759843	1	+	27869803	PATU8988S	viability after 31 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.9533318825352125	[184]	[137,148,NaN]	9	hSpCas9	negative selection	9859989
162761364	162761387	1	-	27869803	PATU8988S	viability after 31 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.29871499950772584	[963]	[209,442,NaN]	-3	hSpCas9	negative selection	9859990
162719099	162719122	1	-	27869803	HPAFII	viability after 35 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	0.12891554541472133	[229]	[60,201,NaN]	0	hSpCas9	negative selection	9942430
162753109	162753132	1	-	27869803	HPAFII	viability after 35 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	1.1232728021391154	[182]	[301,88,NaN]	7	hSpCas9	negative selection	9942434
162754834	162754857	1	+	27869803	HPAFII	viability after 35 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.37988861182151723	[409]	[326,205,NaN]	2	hSpCas9	negative selection	9942435
162755211	162755234	1	-	27869803	HPAFII	viability after 35 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.5327473745567812	[723]	[422,650,NaN]	3	hSpCas9	negative selection	9942436
162759820	162759843	1	+	27869803	HPAFII	viability after 35 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	1.0367552690199207	[108]	[179,37,NaN]	7	hSpCas9	negative selection	9942438
162761364	162761387	1	-	27869803	HPAFII	viability after 35 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-1.4161869005893082	[368]	[61,78,NaN]	-6	hSpCas9	negative selection	9942439
162719099	162719122	1	-	27869803	HPAFII	viability after 31 days	AACTCAAGATAGGCAGCAGCAGG	DDR2	ENSG00000162733	-0.06809708996040412	[229]	[58,192,NaN]	0	hSpCas9	negative selection	10024879
162753109	162753132	1	-	27869803	HPAFII	viability after 31 days	TGGCCTCCTGACATGCCCAGAGG	DDR2	ENSG00000162733	0.9834133284076362	[182]	[315,79,NaN]	7	hSpCas9	negative selection	10024883
162754834	162754857	1	+	27869803	HPAFII	viability after 31 days	GCGGAACCGTCATGGGAAACAGG	DDR2	ENSG00000162733	0.5431075694328098	[409]	[374,291,NaN]	4	hSpCas9	negative selection	10024884
162755211	162755234	1	-	27869803	HPAFII	viability after 31 days	CCGGACAAATCTGGCTACAATGG	DDR2	ENSG00000162733	0.3010397933930218	[723]	[379,631,NaN]	2	hSpCas9	negative selection	10024885
162759820	162759843	1	+	27869803	HPAFII	viability after 31 days	GACCGATGGTGTGTCTGGCCTGG	DDR2	ENSG00000162733	0.6135133996179101	[108]	[117,66,NaN]	4	hSpCas9	negative selection	10024887
162761364	162761387	1	-	27869803	HPAFII	viability after 31 days	CTGGCCATTCGGTGGTGGAGAGG	DDR2	ENSG00000162733	-0.9972376085298975	[368]	[97,109,NaN]	-6	hSpCas9	negative selection	10024888
162759806	162759829	1	+	28162770	P31FUJ	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.5276861126052512	[218]	[370]	6	hSpCas9	negative selection	10142454
162761360	162761383	1	+	28162770	P31FUJ	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	-0.08079911096932868	[26]	[29]	-1	hSpCas9	negative selection	10142455
162766034	162766057	1	-	28162770	P31FUJ	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	0.2676267860951098	[122]	[173]	3	hSpCas9	negative selection	10142456
162773468	162773491	1	+	28162770	P31FUJ	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	0.4070222313412959	[257]	[401]	4	hSpCas9	negative selection	10142457
162776278	162776301	1	+	28162770	P31FUJ	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.04549895807272564	[140]	[170]	0	hSpCas9	negative selection	10142458
162754793	162754816	1	+	28162770	P31FUJ	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	0.0891258904729838	[139]	[174]	0	hSpCas9	negative selection	10142459
162754815	162754838	1	+	28162770	P31FUJ	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.32724772634129007	[661]	[975]	3	hSpCas9	negative selection	10142460
162755207	162755230	1	-	28162770	P31FUJ	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	0.4361592822535456	[277]	[441]	5	hSpCas9	negative selection	10142461
162755696	162755719	1	+	28162770	P31FUJ	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	0.2589108856032942	[686]	[965]	2	hSpCas9	negative selection	10142462
162759882	162759905	1	+	28162770	P31FUJ	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.4548557495274571	[374]	[603]	5	hSpCas9	negative selection	10142463
162759806	162759829	1	+	28162770	TF1	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	NaN	[NaN]	[160]	1	hSpCas9	negative selection	10311820
162761360	162761383	1	+	28162770	TF1	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10311821
162766034	162766057	1	-	28162770	TF1	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10311822
162773468	162773491	1	+	28162770	TF1	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	NaN	[NaN]	[282]	1	hSpCas9	negative selection	10311823
162776278	162776301	1	+	28162770	TF1	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	NaN	[NaN]	[150]	1	hSpCas9	negative selection	10311824
162754793	162754816	1	+	28162770	TF1	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10311825
162754815	162754838	1	+	28162770	TF1	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	NaN	[NaN]	[656]	1	hSpCas9	negative selection	10311826
162755207	162755230	1	-	28162770	TF1	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	NaN	[NaN]	[319]	1	hSpCas9	negative selection	10311827
162755696	162755719	1	+	28162770	TF1	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	NaN	[NaN]	[605]	1	hSpCas9	negative selection	10311828
162759882	162759905	1	+	28162770	TF1	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	NaN	[NaN]	[505]	1	hSpCas9	negative selection	10311829
162759806	162759829	1	+	28162770	SKM1	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.6791924450065527	[64]	[183]	6	hSpCas9	negative selection	10481186
162761360	162761383	1	+	28162770	SKM1	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	-0.3625700793847084	[7]	[10]	-3	hSpCas9	negative selection	10481187
162766034	162766057	1	-	28162770	SKM1	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	-0.14392979290936775	[39]	[63]	-1	hSpCas9	negative selection	10481188
162773468	162773491	1	+	28162770	SKM1	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	1.2764881653773579	[45]	[196]	9	hSpCas9	negative selection	10481189
162776278	162776301	1	+	28162770	SKM1	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.4047691638250168	[46]	[109]	4	hSpCas9	negative selection	10481190
162754793	162754816	1	+	28162770	SKM1	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	0.8073549220576042	[31]	[98]	7	hSpCas9	negative selection	10481191
162754815	162754838	1	+	28162770	SKM1	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	-0.400044784803371	[155]	[208]	-3	hSpCas9	negative selection	10481192
162755207	162755230	1	-	28162770	SKM1	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	-0.2663037918060441	[82]	[121]	-2	hSpCas9	negative selection	10481193
162755696	162755719	1	+	28162770	SKM1	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	0.027708623272216126	[186]	[336]	0	hSpCas9	negative selection	10481194
162759882	162759905	1	+	28162770	SKM1	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.7384036984551716	[78]	[232]	7	hSpCas9	negative selection	10481195
162759806	162759829	1	+	28162770	SKM1	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.6791924450065527	[64]	[183]	6	hSpCas9	negative selection	10650552
162761360	162761383	1	+	28162770	SKM1	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	-0.3625700793847084	[7]	[10]	-3	hSpCas9	negative selection	10650553
162766034	162766057	1	-	28162770	SKM1	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	-0.14392979290936775	[39]	[63]	-1	hSpCas9	negative selection	10650554
162773468	162773491	1	+	28162770	SKM1	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	1.2764881653773579	[45]	[196]	9	hSpCas9	negative selection	10650555
162776278	162776301	1	+	28162770	SKM1	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.4047691638250168	[46]	[109]	4	hSpCas9	negative selection	10650556
162754793	162754816	1	+	28162770	SKM1	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	0.8073549220576042	[31]	[98]	7	hSpCas9	negative selection	10650557
162754815	162754838	1	+	28162770	SKM1	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	-0.400044784803371	[155]	[208]	-3	hSpCas9	negative selection	10650558
162755207	162755230	1	-	28162770	SKM1	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	-0.2663037918060441	[82]	[121]	-2	hSpCas9	negative selection	10650559
162755696	162755719	1	+	28162770	SKM1	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	0.027708623272216126	[186]	[336]	0	hSpCas9	negative selection	10650560
162759882	162759905	1	+	28162770	SKM1	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.7384036984551716	[78]	[232]	7	hSpCas9	negative selection	10650561
162759806	162759829	1	+	28162770	PL21	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.06462464383283906	[289]	[131]	0	hSpCas9	negative selection	10819918
162761360	162761383	1	+	28162770	PL21	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	2.5220677093766826	[13]	[34]	9	hSpCas9	negative selection	10819919
162766034	162766057	1	-	28162770	PL21	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	-0.12651089064044552	[152]	[60]	-1	hSpCas9	negative selection	10819920
162773468	162773491	1	+	28162770	PL21	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	-0.09998411007969397	[196]	[79]	0	hSpCas9	negative selection	10819921
162776278	162776301	1	+	28162770	PL21	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	-0.413392038428607	[152]	[49]	-3	hSpCas9	negative selection	10819922
162754793	162754816	1	+	28162770	PL21	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	-0.015897311807304193	[150]	[64]	0	hSpCas9	negative selection	10819923
162754815	162754838	1	+	28162770	PL21	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.5924570372680803	[383]	[251]	5	hSpCas9	negative selection	10819924
162755207	162755230	1	-	28162770	PL21	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	1.9953198226008222	[203]	[353]	9	hSpCas9	negative selection	10819925
162755696	162755719	1	+	28162770	PL21	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	0.38894262613732167	[657]	[374]	3	hSpCas9	negative selection	10819926
162759882	162759905	1	+	28162770	PL21	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.8936265719886454	[255]	[206]	7	hSpCas9	negative selection	10819927
162759806	162759829	1	+	28162770	P31FUJ	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.5276861126052512	[218]	[370]	6	hSpCas9	negative selection	10989284
162761360	162761383	1	+	28162770	P31FUJ	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	-0.08079911096932868	[26]	[29]	-1	hSpCas9	negative selection	10989285
162766034	162766057	1	-	28162770	P31FUJ	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	0.2676267860951098	[122]	[173]	3	hSpCas9	negative selection	10989286
162773468	162773491	1	+	28162770	P31FUJ	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	0.4070222313412959	[257]	[401]	4	hSpCas9	negative selection	10989287
162776278	162776301	1	+	28162770	P31FUJ	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.04549895807272564	[140]	[170]	0	hSpCas9	negative selection	10989288
162754793	162754816	1	+	28162770	P31FUJ	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	0.0891258904729838	[139]	[174]	0	hSpCas9	negative selection	10989289
162754815	162754838	1	+	28162770	P31FUJ	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.32724772634129007	[661]	[975]	3	hSpCas9	negative selection	10989290
162755207	162755230	1	-	28162770	P31FUJ	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	0.4361592822535456	[277]	[441]	5	hSpCas9	negative selection	10989291
162755696	162755719	1	+	28162770	P31FUJ	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	0.2589108856032942	[686]	[965]	2	hSpCas9	negative selection	10989292
162759882	162759905	1	+	28162770	P31FUJ	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.4548557495274571	[374]	[603]	5	hSpCas9	negative selection	10989293
162759806	162759829	1	+	28162770	OCIAML5	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.33861699074511287	[137]	[314]	3	hSpCas9	negative selection	11158650
162761360	162761383	1	+	28162770	OCIAML5	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	-0.32599775919640894	[24]	[35]	-2	hSpCas9	negative selection	11158651
162766034	162766057	1	-	28162770	OCIAML5	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	-1.0803355585371142	[81]	[69]	-6	hSpCas9	negative selection	11158652
162773468	162773491	1	+	28162770	OCIAML5	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	0.3399522014289322	[143]	[328]	3	hSpCas9	negative selection	11158653
162776278	162776301	1	+	28162770	OCIAML5	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.42571442033898316	[72]	[176]	3	hSpCas9	negative selection	11158654
162754793	162754816	1	+	28162770	OCIAML5	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	0.8546412022095282	[52]	[172]	7	hSpCas9	negative selection	11158655
162754815	162754838	1	+	28162770	OCIAML5	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	-0.6813820563528719	[421]	[474]	-4	hSpCas9	negative selection	11158656
162755207	162755230	1	-	28162770	OCIAML5	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	0.3982859318133378	[218]	[520]	3	hSpCas9	negative selection	11158657
162755696	162755719	1	+	28162770	OCIAML5	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	-0.0863180760687614	[396]	[674]	0	hSpCas9	negative selection	11158658
162759882	162759905	1	+	28162770	OCIAML5	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.48391711924478453	[142]	[360]	4	hSpCas9	negative selection	11158659
162759806	162759829	1	+	28162770	EOL1	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.009603541523307335	[493]	[261]	0	hSpCas9	negative selection	11328016
162761360	162761383	1	+	28162770	EOL1	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	-0.4624753515387128	[33]	[12]	-3	hSpCas9	negative selection	11328017
162766034	162766057	1	-	28162770	EOL1	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	-0.9433486924221204	[291]	[79]	-6	hSpCas9	negative selection	11328018
162773468	162773491	1	+	28162770	EOL1	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	-0.6381847817671562	[321]	[108]	-4	hSpCas9	negative selection	11328019
162776278	162776301	1	+	28162770	EOL1	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.15492896008557697	[282]	[165]	1	hSpCas9	negative selection	11328020
162754793	162754816	1	+	28162770	EOL1	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	1.3354336275789112	[260]	[346]	9	hSpCas9	negative selection	11328021
162754815	162754838	1	+	28162770	EOL1	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.6819145577964623	[645]	[545]	6	hSpCas9	negative selection	11328022
162755207	162755230	1	-	28162770	EOL1	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	1.6257422347149189	[293]	[477]	9	hSpCas9	negative selection	11328023
162755696	162755719	1	+	28162770	EOL1	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	-0.1289677377564673	[713]	[343]	-1	hSpCas9	negative selection	11328024
162759882	162759905	1	+	28162770	EOL1	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.35626401199600854	[343]	[231]	3	hSpCas9	negative selection	11328025
162759806	162759829	1	+	28162770	MOLM13	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.11787167411614508	[375]	[294]	0	hSpCas9	negative selection	11497382
162761360	162761383	1	+	28162770	MOLM13	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	0.1630348000161579	[20]	[16]	1	hSpCas9	negative selection	11497383
162766034	162766057	1	-	28162770	MOLM13	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	0.09013289834519461	[190]	[146]	0	hSpCas9	negative selection	11497384
162773468	162773491	1	+	28162770	MOLM13	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	0.8371231912102978	[263]	[340]	6	hSpCas9	negative selection	11497385
162776278	162776301	1	+	28162770	MOLM13	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.4416578399713991	[221]	[217]	3	hSpCas9	negative selection	11497386
162754793	162754816	1	+	28162770	MOLM13	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	1.7610345758029118	[161]	[396]	9	hSpCas9	negative selection	11497387
162754815	162754838	1	+	28162770	MOLM13	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.2667068562274719	[798]	[694]	2	hSpCas9	negative selection	11497388
162755207	162755230	1	-	28162770	MOLM13	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	1.2744946569025988	[274]	[480]	8	hSpCas9	negative selection	11497389
162755696	162755719	1	+	28162770	MOLM13	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	-0.4991222065015105	[734]	[375]	-3	hSpCas9	negative selection	11497390
162759882	162759905	1	+	28162770	MOLM13	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	1.5962561107223905	[359]	[786]	9	hSpCas9	negative selection	11497391
162759806	162759829	1	+	28162770	HEL	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	-0.11365729211475073	[298]	[176]	-1	hSpCas9	negative selection	11666748
162761360	162761383	1	+	28162770	HEL	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	-0.06352996494293306	[30]	[18]	0	hSpCas9	negative selection	11666749
162766034	162766057	1	-	28162770	HEL	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	0.03575002494920182	[197]	[129]	0	hSpCas9	negative selection	11666750
162773468	162773491	1	+	28162770	HEL	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	0.4850179701451706	[308]	[276]	4	hSpCas9	negative selection	11666751
162776278	162776301	1	+	28162770	HEL	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.6050684140343019	[193]	[188]	5	hSpCas9	negative selection	11666752
162754793	162754816	1	+	28162770	HEL	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	0.7472694154716637	[172]	[185]	6	hSpCas9	negative selection	11666753
162754815	162754838	1	+	28162770	HEL	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	-0.17439711084983278	[702]	[398]	-1	hSpCas9	negative selection	11666754
162755207	162755230	1	-	28162770	HEL	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	0.5667899787670585	[272]	[258]	5	hSpCas9	negative selection	11666755
162755696	162755719	1	+	28162770	HEL	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	-0.7302346077119428	[675]	[260]	-5	hSpCas9	negative selection	11666756
162759882	162759905	1	+	28162770	HEL	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.2776759743870173	[330]	[256]	2	hSpCas9	negative selection	11666757
162759806	162759829	1	+	28162770	MV411	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	0.3436528660420784	[231]	[247]	3	hSpCas9	negative selection	11836114
162761360	162761383	1	+	28162770	MV411	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	0.7404775620628921	[26]	[37]	6	hSpCas9	negative selection	11836115
162766034	162766057	1	-	28162770	MV411	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	-0.2541089417507435	[125]	[88]	-2	hSpCas9	negative selection	11836116
162773468	162773491	1	+	28162770	MV411	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	0.5967718030107895	[145]	[185]	5	hSpCas9	negative selection	11836117
162776278	162776301	1	+	28162770	MV411	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	-0.9624855185914559	[191]	[82]	-6	hSpCas9	negative selection	11836118
162754793	162754816	1	+	28162770	MV411	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	0.38278940367766157	[121]	[133]	3	hSpCas9	negative selection	11836119
162754815	162754838	1	+	28162770	MV411	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.19957123951751687	[428]	[414]	1	hSpCas9	negative selection	11836120
162755207	162755230	1	-	28162770	MV411	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	1.0270474823574751	[179]	[308]	8	hSpCas9	negative selection	11836121
162755696	162755719	1	+	28162770	MV411	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	-0.23700984998128938	[588]	[420]	-2	hSpCas9	negative selection	11836122
162759882	162759905	1	+	28162770	MV411	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.6880101421687568	[237]	[322]	6	hSpCas9	negative selection	11836123
162759806	162759829	1	+	28162770	MONOMAC1	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	-0.1970368470595537	[143]	[143]	-2	hSpCas9	negative selection	12005480
162761360	162761383	1	+	28162770	MONOMAC1	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	0.9404666766903813	[9]	[21]	8	hSpCas9	negative selection	12005481
162766034	162766057	1	-	28162770	MONOMAC1	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	0.9848014759262596	[66]	[151]	8	hSpCas9	negative selection	12005482
162773468	162773491	1	+	28162770	MONOMAC1	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	0.16553323232515468	[132]	[170]	1	hSpCas9	negative selection	12005483
162776278	162776301	1	+	28162770	MONOMAC1	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.7235286854460412	[83]	[158]	7	hSpCas9	negative selection	12005484
162754793	162754816	1	+	28162770	MONOMAC1	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	0.7088409755758963	[94]	[177]	6	hSpCas9	negative selection	12005485
162754815	162754838	1	+	28162770	MONOMAC1	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	0.78608933437605	[257]	[509]	7	hSpCas9	negative selection	12005486
162755207	162755230	1	-	28162770	MONOMAC1	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	-0.5026631296178155	[109]	[88]	-4	hSpCas9	negative selection	12005487
162755696	162755719	1	+	28162770	MONOMAC1	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	0.542811255639774	[399]	[667]	5	hSpCas9	negative selection	12005488
162759882	162759905	1	+	28162770	MONOMAC1	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	-0.6052530804823835	[210]	[158]	-5	hSpCas9	negative selection	12005489
162759806	162759829	1	+	28162770	OCIAML2	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	-0.11553486641959967	[42]	[219]	-1	hSpCas9	negative selection	12174846
162761360	162761383	1	+	28162770	OCIAML2	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	-1.0921182019884315	[4]	[12]	-6	hSpCas9	negative selection	12174847
162766034	162766057	1	-	28162770	OCIAML2	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	-1.4957208062049916	[28]	[56]	-7	hSpCas9	negative selection	12174848
162773468	162773491	1	+	28162770	OCIAML2	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	0.3571891993751585	[39]	[283]	3	hSpCas9	negative selection	12174849
162776278	162776301	1	+	28162770	OCIAML2	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	-0.7462642678555885	[22]	[75]	-5	hSpCas9	negative selection	12174850
162754793	162754816	1	+	28162770	OCIAML2	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	0.2640797949836772	[31]	[212]	2	hSpCas9	negative selection	12174851
162754815	162754838	1	+	28162770	OCIAML2	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	-0.016187358692539178	[78]	[432]	0	hSpCas9	negative selection	12174852
162755207	162755230	1	-	28162770	OCIAML2	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	0.7137947458952664	[32]	[299]	7	hSpCas9	negative selection	12174853
162755696	162755719	1	+	28162770	OCIAML2	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	0.07989917841512129	[105]	[620]	0	hSpCas9	negative selection	12174854
162759882	162759905	1	+	28162770	OCIAML2	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	-0.04178652643828695	[51]	[279]	0	hSpCas9	negative selection	12174855
162759806	162759829	1	+	28162770	OCIAML3	viability	GGGCTAGGCCAATTGACCGATGG	DDR2	ENSG00000162733	-0.8681826037631573	[77]	[128]	-6	hSpCas9	negative selection	12344212
162761360	162761383	1	+	28162770	OCIAML3	viability	GGTGCCTCTCCACCACCGAATGG	DDR2	ENSG00000162733	-2.594007640324163	[1]	[0]	-9	hSpCas9	negative selection	12344213
162766034	162766057	1	-	28162770	OCIAML3	viability	TGTGGGTGCCATAGGAGAGGTGG	DDR2	ENSG00000162733	0.25398926623078677	[39]	[143]	2	hSpCas9	negative selection	12344214
162773468	162773491	1	+	28162770	OCIAML3	viability	GGTTCATCTCTGTGAAGTGGAGG	DDR2	ENSG00000162733	-0.05026780232951994	[70]	[206]	0	hSpCas9	negative selection	12344215
162776278	162776301	1	+	28162770	OCIAML3	viability	ATGAGCAGGAACCTGTACAGTGG	DDR2	ENSG00000162733	0.5046203924035526	[52]	[226]	5	hSpCas9	negative selection	12344216
162754793	162754816	1	+	28162770	OCIAML3	viability	AAGATCAATTACAGTCGGGATGG	DDR2	ENSG00000162733	-1.0555877255400374	[41]	[60]	-6	hSpCas9	negative selection	12344217
162754815	162754838	1	+	28162770	OCIAML3	viability	GCACTCGCTGGATCTCTTGGCGG	DDR2	ENSG00000162733	-0.17487738641143635	[131]	[352]	-1	hSpCas9	negative selection	12344218
162755207	162755230	1	-	28162770	OCIAML3	viability	ACAAATCTGGCTACAATGGGCGG	DDR2	ENSG00000162733	0.31852951842549737	[50]	[191]	3	hSpCas9	negative selection	12344219
162755696	162755719	1	+	28162770	OCIAML3	viability	CAGCAGTTTGTACTCCCTGGAGG	DDR2	ENSG00000162733	0.07685493380264008	[162]	[518]	0	hSpCas9	negative selection	12344220
162759882	162759905	1	+	28162770	OCIAML3	viability	GCTATGACTATGTGGGCTGGCGG	DDR2	ENSG00000162733	0.34256697953420323	[92]	[355]	3	hSpCas9	negative selection	12344221