Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1961
• Symbol: EGR4
• Description: early growth response 4

DataSource: http://genomecrispr.dkfz.de/#!/results/EGR4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
73293617	73293640	2	-	26472758	Jiyoye	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	-0.02608587639187765	[238]	[176]	0	hSpCas9	negative selection	48894
73293565	73293588	2	-	26472758	Jiyoye	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	-0.3929298014723428	[396]	[227]	-3	hSpCas9	negative selection	48895
73293460	73293483	2	+	26472758	Jiyoye	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	-0.2173154834019202	[36]	[23]	-1	hSpCas9	negative selection	48896
73293406	73293429	2	-	26472758	Jiyoye	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	0.21453030356347744	[95]	[83]	1	hSpCas9	negative selection	48897
73293267	73293290	2	+	26472758	Jiyoye	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	-0.17778711921528254	[146]	[97]	-1	hSpCas9	negative selection	48898
73293222	73293245	2	+	26472758	Jiyoye	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.9096757220350566	[23]	[33]	6	hSpCas9	negative selection	48899
73293177	73293200	2	+	26472758	Jiyoye	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	1.9921378822270295	[10]	[32]	8	hSpCas9	negative selection	48900
73293520	73293543	2	-	26472758	Jiyoye	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	0.9432282817460833	[19]	[28]	6	hSpCas9	negative selection	48901
73293428	73293451	2	-	26472758	Jiyoye	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	1.1847829601694255	[34]	[59]	7	hSpCas9	negative selection	48902
73293290	73293313	2	+	26472758	Jiyoye	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	0.2210790893924155	[156]	[137]	1	hSpCas9	negative selection	48903
73293617	73293640	2	-	26472758	KBM7	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.18895166203609876	[750,470]	[360,285]	2	hSpCas9	negative selection	240012
73293565	73293588	2	-	26472758	KBM7	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	0.3544297138512785	[866,822]	[554,467]	4	hSpCas9	negative selection	240013
73293460	73293483	2	+	26472758	KBM7	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	0.09968737891594959	[132,70]	[86,16]	1	hSpCas9	negative selection	240014
73293406	73293429	2	-	26472758	KBM7	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	0.416859877653043	[370,335]	[252,193]	4	hSpCas9	negative selection	240015
73293267	73293290	2	+	26472758	KBM7	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	0.2098107712104902	[890,524]	[372,379]	2	hSpCas9	negative selection	240016
73293222	73293245	2	+	26472758	KBM7	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.37242643321232927	[192,78]	[95,64]	4	hSpCas9	negative selection	240017
73293177	73293200	2	+	26472758	KBM7	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.06491407328768739	[99,74]	[30,52]	0	hSpCas9	negative selection	240018
73293520	73293543	2	-	26472758	KBM7	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-1.02247126101057	[25,94]	[16,12]	-7	hSpCas9	negative selection	240019
73293428	73293451	2	-	26472758	KBM7	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	-0.5553593731806333	[457,394]	[105,162]	-5	hSpCas9	negative selection	240020
73293290	73293313	2	+	26472758	KBM7	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.8869860779019871	[485,293]	[84,107]	-6	hSpCas9	negative selection	240021
73293617	73293640	2	-	26472758	Raji	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.18311086153684447	[333]	[87]	1	hSpCas9	negative selection	431130
73293565	73293588	2	-	26472758	Raji	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	0.04454266180336819	[609]	[145]	0	hSpCas9	negative selection	431131
73293460	73293483	2	+	26472758	Raji	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	0.24940254024602737	[28]	[7]	2	hSpCas9	negative selection	431132
73293406	73293429	2	-	26472758	Raji	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	0.08243717824336877	[174]	[42]	0	hSpCas9	negative selection	431133
73293267	73293290	2	+	26472758	Raji	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	-0.8351309699656404	[245]	[31]	-6	hSpCas9	negative selection	431134
73293222	73293245	2	+	26472758	Raji	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	1.4069438172325073	[51]	[31]	9	hSpCas9	negative selection	431135
73293177	73293200	2	+	26472758	Raji	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	1.6479519167363024	[10]	[7]	9	hSpCas9	negative selection	431136
73293520	73293543	2	-	26472758	Raji	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	0.8849911140371516	[41]	[17]	7	hSpCas9	negative selection	431137
73293428	73293451	2	-	26472758	Raji	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	-0.20489438948004363	[297]	[59]	-2	hSpCas9	negative selection	431138
73293290	73293313	2	+	26472758	Raji	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.2711280878801303	[233]	[44]	-2	hSpCas9	negative selection	431139
73293617	73293640	2	-	26472758	K562	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.5927074090907044	[563]	[717]	5	hSpCas9	negative selection	622248
73293565	73293588	2	-	26472758	K562	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	0.5799825925003101	[694]	[876]	5	hSpCas9	negative selection	622249
73293460	73293483	2	+	26472758	K562	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	0.8495591103252331	[70]	[107]	7	hSpCas9	negative selection	622250
73293406	73293429	2	-	26472758	K562	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	-0.23841875682685668	[333]	[238]	-2	hSpCas9	negative selection	622251
73293267	73293290	2	+	26472758	K562	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	-0.047567051863476234	[452]	[369]	0	hSpCas9	negative selection	622252
73293222	73293245	2	+	26472758	K562	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.5174372220728629	[119]	[144]	4	hSpCas9	negative selection	622253
73293177	73293200	2	+	26472758	K562	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-0.5596610623582965	[109]	[62]	-4	hSpCas9	negative selection	622254
73293520	73293543	2	-	26472758	K562	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-0.7555812723335533	[55]	[27]	-4	hSpCas9	negative selection	622255
73293428	73293451	2	-	26472758	K562	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	-0.3982592709109968	[305]	[195]	-3	hSpCas9	negative selection	622256
73293290	73293313	2	+	26472758	K562	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	0.17555686952164273	[235]	[224]	1	hSpCas9	negative selection	622257
73292104	73292127	2	-	26627737	DLD1	viability	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	-0.3406742524685511	[183]	[64,51,22]	-4	hSpCas9	negative selection	812649
73292441	73292464	2	+	26627737	DLD1	viability	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.03461475627302468	[785]	[264,159,315]	0	hSpCas9	negative selection	812650
73292668	73292691	2	+	26627737	DLD1	viability	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	1.0333124420265771	[572]	[319,496,298]	8	hSpCas9	negative selection	812651
73293177	73293200	2	+	26627737	DLD1	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-1.5190379414661186	[223]	[60,5,7]	-8	hSpCas9	negative selection	812652
73293525	73293548	2	-	26627737	DLD1	viability	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	0.4229831985342323	[932]	[342,398,425]	4	hSpCas9	negative selection	812653
73293571	73293594	2	+	26627737	DLD1	viability	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	-0.9790278780108091	[442]	[51,79,77]	-7	hSpCas9	negative selection	812654
73292104	73292127	2	-	26627737	GBM cells	viability after 5 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	0.4117265898510065	[81]	[66,49]	6	hSpCas9	negative selection	894964
73292441	73292464	2	+	26627737	GBM cells	viability after 5 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	-0.3569607393752422	[602]	[248,255]	-5	hSpCas9	negative selection	894965
73292668	73292691	2	+	26627737	GBM cells	viability after 5 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.27376228404883063	[363]	[270,200]	4	hSpCas9	negative selection	894966
73293177	73293200	2	+	26627737	GBM cells	viability after 5 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.09724259133166413	[94]	[50,57]	1	hSpCas9	negative selection	894967
73293525	73293548	2	-	26627737	GBM cells	viability after 5 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.42159214493247865	[506]	[254,150]	-6	hSpCas9	negative selection	894968
73293571	73293594	2	+	26627737	GBM cells	viability after 5 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.8773270126775397	[100]	[100,97]	9	hSpCas9	negative selection	894969
73292104	73292127	2	-	26627737	GBM cells	viability after 13 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	0.46361172022979	[81]	[78,46]	6	hSpCas9	negative selection	977279
73292441	73292464	2	+	26627737	GBM cells	viability after 13 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	-0.16743264979512795	[602]	[319,267]	-2	hSpCas9	negative selection	977280
73292668	73292691	2	+	26627737	GBM cells	viability after 13 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.07004853219380047	[363]	[235,183]	0	hSpCas9	negative selection	977281
73293177	73293200	2	+	26627737	GBM cells	viability after 13 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.8076323025474277	[94]	[119,65]	8	hSpCas9	negative selection	977282
73293525	73293548	2	-	26627737	GBM cells	viability after 13 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.6924147635460136	[506]	[215,132]	-7	hSpCas9	negative selection	977283
73293571	73293594	2	+	26627737	GBM cells	viability after 13 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.5569154124020882	[100]	[73,85]	7	hSpCas9	negative selection	977284
73292104	73292127	2	-	26627737	GBM cells	viability after 21 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	0.8264620431746778	[81]	[78,78]	7	hSpCas9	negative selection	1059594
73292441	73292464	2	+	26627737	GBM cells	viability after 21 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	-0.03515581867795481	[602]	[349,291]	0	hSpCas9	negative selection	1059595
73292668	73292691	2	+	26627737	GBM cells	viability after 21 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	-0.16176822169430255	[363]	[181,171]	-1	hSpCas9	negative selection	1059596
73293177	73293200	2	+	26627737	GBM cells	viability after 21 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.7248515277156384	[94]	[89,80]	7	hSpCas9	negative selection	1059597
73293525	73293548	2	-	26627737	GBM cells	viability after 21 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.5270891783267395	[506]	[222,161]	-5	hSpCas9	negative selection	1059598
73293571	73293594	2	+	26627737	GBM cells	viability after 21 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.5571143709496738	[100]	[86,74]	5	hSpCas9	negative selection	1059599
73292104	73292127	2	-	26627737	RPE1	viability after 9 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	3.474282954718616	[26]	[34,169]	9	hSpCas9	negative selection	1141909
73292441	73292464	2	+	26627737	RPE1	viability after 9 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.23275588110641587	[1915]	[665,754]	1	hSpCas9	negative selection	1141910
73292668	73292691	2	+	26627737	RPE1	viability after 9 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.8920476216690287	[1008]	[542,641]	6	hSpCas9	negative selection	1141911
73293177	73293200	2	+	26627737	RPE1	viability after 9 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-0.9041785797796071	[398]	[95,28]	-6	hSpCas9	negative selection	1141912
73293525	73293548	2	-	26627737	RPE1	viability after 9 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.7020790392877232	[2677]	[534,489]	-5	hSpCas9	negative selection	1141913
73293571	73293594	2	+	26627737	RPE1	viability after 9 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	-0.3893267630764433	[545]	[133,125]	-3	hSpCas9	negative selection	1141914
73292104	73292127	2	-	26627737	RPE1	viability after 12 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	3.8448309067294444	[26]	[60,149]	9	hSpCas9	negative selection	1224224
73292441	73292464	2	+	26627737	RPE1	viability after 12 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.22913213792013365	[1915]	[649,553]	1	hSpCas9	negative selection	1224225
73292668	73292691	2	+	26627737	RPE1	viability after 12 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.7618153019271658	[1008]	[498,417]	5	hSpCas9	negative selection	1224226
73293177	73293200	2	+	26627737	RPE1	viability after 12 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-1.1019270719935759	[398]	[30,69]	-6	hSpCas9	negative selection	1224227
73293525	73293548	2	-	26627737	RPE1	viability after 12 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.42743375236266345	[2677]	[483,588]	-3	hSpCas9	negative selection	1224228
73293571	73293594	2	+	26627737	RPE1	viability after 12 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.32400101084493754	[545]	[187,178]	2	hSpCas9	negative selection	1224229
73292104	73292127	2	-	26627737	RPE1	viability after 15 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	4.272560649762714	[26]	[112,180]	9	hSpCas9	negative selection	1306539
73292441	73292464	2	+	26627737	RPE1	viability after 15 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.2847529168204115	[1915]	[926,402]	1	hSpCas9	negative selection	1306540
73292668	73292691	2	+	26627737	RPE1	viability after 15 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	1.0477478581454667	[1008]	[614,565]	6	hSpCas9	negative selection	1306541
73293177	73293200	2	+	26627737	RPE1	viability after 15 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-0.45518383692832365	[398]	[91,72]	-3	hSpCas9	negative selection	1306542
73293525	73293548	2	-	26627737	RPE1	viability after 15 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.43187477871321667	[2677]	[613,510]	-3	hSpCas9	negative selection	1306543
73293571	73293594	2	+	26627737	RPE1	viability after 15 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	-0.4332875888640889	[545]	[120,107]	-3	hSpCas9	negative selection	1306544
73292104	73292127	2	-	26627737	RPE1	viability after 18 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	4.201533127471152	[26]	[164,100]	9	hSpCas9	negative selection	1388854
73292441	73292464	2	+	26627737	RPE1	viability after 18 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.37666848670217656	[1915]	[680,660]	2	hSpCas9	negative selection	1388855
73292668	73292691	2	+	26627737	RPE1	viability after 18 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.7602776633282542	[1008]	[525,391]	4	hSpCas9	negative selection	1388856
73293177	73293200	2	+	26627737	RPE1	viability after 18 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-0.47282103573498957	[398]	[50,105]	-3	hSpCas9	negative selection	1388857
73293525	73293548	2	-	26627737	RPE1	viability after 18 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.3632958854916295	[2677]	[512,613]	-2	hSpCas9	negative selection	1388858
73293571	73293594	2	+	26627737	RPE1	viability after 18 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.26316400367420145	[545]	[171,181]	1	hSpCas9	negative selection	1388859
73292104	73292127	2	-	26627737	HeLa	viability after 8 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	-1.6821898788934058	[295]	[106,0,27]	-9	hSpCas9	negative selection	1471169
73292441	73292464	2	+	26627737	HeLa	viability after 8 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.09971293153182836	[791]	[361,548,206]	1	hSpCas9	negative selection	1471170
73292668	73292691	2	+	26627737	HeLa	viability after 8 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.10991635686488144	[752]	[483,303,304]	1	hSpCas9	negative selection	1471171
73293177	73293200	2	+	26627737	HeLa	viability after 8 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.8588229541784549	[89]	[42,123,41]	7	hSpCas9	negative selection	1471172
73293525	73293548	2	-	26627737	HeLa	viability after 8 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	0.02919511515312645	[741]	[354,323,315]	0	hSpCas9	negative selection	1471173
73293571	73293594	2	+	26627737	HeLa	viability after 8 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.3329059575156974	[272]	[119,211,112]	3	hSpCas9	negative selection	1471174
73292104	73292127	2	-	26627737	HeLa	viability after 12 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	-2.0293158984724635	[295]	[33,48,4]	-9	hSpCas9	negative selection	1553484
73292441	73292464	2	+	26627737	HeLa	viability after 12 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	-0.25942286819846205	[791]	[272,398,134]	-2	hSpCas9	negative selection	1553485
73292668	73292691	2	+	26627737	HeLa	viability after 12 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.17849698000188907	[752]	[454,356,246]	1	hSpCas9	negative selection	1553486
73293177	73293200	2	+	26627737	HeLa	viability after 12 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.11359657613191176	[89]	[52,59,5]	1	hSpCas9	negative selection	1553487
73293525	73293548	2	-	26627737	HeLa	viability after 12 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.6659355457815513	[741]	[300,154,130]	-5	hSpCas9	negative selection	1553488
73293571	73293594	2	+	26627737	HeLa	viability after 12 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.44919533842872805	[272]	[255,97,116]	4	hSpCas9	negative selection	1553489
73292104	73292127	2	-	26627737	HeLa	viability after 15 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	-0.7484294995033361	[295]	[91,1,124]	-6	hSpCas9	negative selection	1635799
73292441	73292464	2	+	26627737	HeLa	viability after 15 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.391346486766994	[791]	[131,565,586]	3	hSpCas9	negative selection	1635800
73292668	73292691	2	+	26627737	HeLa	viability after 15 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.36121662033460866	[752]	[473,375,324]	3	hSpCas9	negative selection	1635801
73293177	73293200	2	+	26627737	HeLa	viability after 15 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	1.1316417598762816	[89]	[20,50,176]	7	hSpCas9	negative selection	1635802
73293525	73293548	2	-	26627737	HeLa	viability after 15 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.34000135988813385	[741]	[312,295,94]	-3	hSpCas9	negative selection	1635803
73293571	73293594	2	+	26627737	HeLa	viability after 15 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.3911010195639976	[272]	[201,94,138]	3	hSpCas9	negative selection	1635804
73292104	73292127	2	-	26627737	HeLa	viability after 18 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	-0.816755838691006	[295]	[54,1,124]	-6	hSpCas9	negative selection	1718114
73292441	73292464	2	+	26627737	HeLa	viability after 18 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.4144896835205969	[791]	[91,480,586]	3	hSpCas9	negative selection	1718115
73292668	73292691	2	+	26627737	HeLa	viability after 18 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.3748852755341915	[752]	[319,317,324]	3	hSpCas9	negative selection	1718116
73293177	73293200	2	+	26627737	HeLa	viability after 18 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	1.1401738074893504	[89]	[15,40,176]	7	hSpCas9	negative selection	1718117
73293525	73293548	2	-	26627737	HeLa	viability after 18 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.4287296075183734	[741]	[191,232,94]	-4	hSpCas9	negative selection	1718118
73293571	73293594	2	+	26627737	HeLa	viability after 18 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.36197852959696986	[272]	[127,80,138]	3	hSpCas9	negative selection	1718119
73292104	73292127	2	-	26627737	HCT116	viability after 6 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	0.9205802102384126	[419]	[104,135]	5	hSpCas9	negative selection	1800429
73292441	73292464	2	+	26627737	HCT116	viability after 6 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.35864535481575577	[1737]	[194,435]	2	hSpCas9	negative selection	1800430
73292668	73292691	2	+	26627737	HCT116	viability after 6 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	1.638372893946846	[538]	[315,234]	8	hSpCas9	negative selection	1800431
73293177	73293200	2	+	26627737	HCT116	viability after 6 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-1.134238692756503	[169]	[26,3]	-6	hSpCas9	negative selection	1800432
73293525	73293548	2	-	26627737	HCT116	viability after 6 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	0.7127108505078759	[1308]	[266,375]	4	hSpCas9	negative selection	1800433
73293571	73293594	2	+	26627737	HCT116	viability after 6 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	1.2081430732099045	[206]	[167,23]	6	hSpCas9	negative selection	1800434
73292104	73292127	2	-	26627737	HCT116	viability after 8 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	-0.5875276637670391	[161]	[55,49,71]	-6	hSpCas9	negative selection	1882744
73292441	73292464	2	+	26627737	HCT116	viability after 8 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.8394494151911267	[371]	[381,381,336]	7	hSpCas9	negative selection	1882745
73292668	73292691	2	+	26627737	HCT116	viability after 8 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.4671803673925096	[363]	[194,328,305]	5	hSpCas9	negative selection	1882746
73293177	73293200	2	+	26627737	HCT116	viability after 8 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.4421410973727	[45]	[15,53,32]	4	hSpCas9	negative selection	1882747
73293525	73293548	2	-	26627737	HCT116	viability after 8 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.7692305025231023	[685]	[207,225,230]	-7	hSpCas9	negative selection	1882748
73293571	73293594	2	+	26627737	HCT116	viability after 8 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.20154651249942013	[168]	[114,148,57]	2	hSpCas9	negative selection	1882749
73292104	73292127	2	-	26627737	HCT116	viability after 9 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	0.7715715380709669	[419]	[86,273]	5	hSpCas9	negative selection	1965059
73292441	73292464	2	+	26627737	HCT116	viability after 9 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.5191638668719452	[1737]	[773,578]	4	hSpCas9	negative selection	1965060
73292668	73292691	2	+	26627737	HCT116	viability after 9 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.20236011894934233	[538]	[302,56]	1	hSpCas9	negative selection	1965061
73293177	73293200	2	+	26627737	HCT116	viability after 9 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	1.4885754756021696	[169]	[180,84]	8	hSpCas9	negative selection	1965062
73293525	73293548	2	-	26627737	HCT116	viability after 9 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	0.7432776159655619	[1308]	[483,664]	5	hSpCas9	negative selection	1965063
73293571	73293594	2	+	26627737	HCT116	viability after 9 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.6377676085562412	[206]	[85,85]	4	hSpCas9	negative selection	1965064
73292104	73292127	2	-	26627737	HCT116	viability after 12 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	0.49698627121810945	[161]	[58,168,138]	5	hSpCas9	negative selection	2047374
73292441	73292464	2	+	26627737	HCT116	viability after 12 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.7362944582629649	[371]	[310,353,313]	6	hSpCas9	negative selection	2047375
73292668	73292691	2	+	26627737	HCT116	viability after 12 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.20185375647061793	[363]	[141,264,260]	2	hSpCas9	negative selection	2047376
73293177	73293200	2	+	26627737	HCT116	viability after 12 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	1.06714396827338	[45]	[54,26,68]	8	hSpCas9	negative selection	2047377
73293525	73293548	2	-	26627737	HCT116	viability after 12 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.2854390567574904	[685]	[210,384,300]	-3	hSpCas9	negative selection	2047378
73293571	73293594	2	+	26627737	HCT116	viability after 12 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.10298141899650415	[168]	[51,137,100]	1	hSpCas9	negative selection	2047379
73292104	73292127	2	-	26627737	HCT116	viability after 15 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	-0.18120436450358246	[161]	[76,123,44]	-2	hSpCas9	negative selection	2129689
73292441	73292464	2	+	26627737	HCT116	viability after 15 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.6480076606048026	[371]	[507,232,284]	6	hSpCas9	negative selection	2129690
73292668	73292691	2	+	26627737	HCT116	viability after 15 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.1958455238475758	[363]	[220,332,162]	2	hSpCas9	negative selection	2129691
73293177	73293200	2	+	26627737	HCT116	viability after 15 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	1.1039603101310673	[45]	[82,71,18]	8	hSpCas9	negative selection	2129692
73293525	73293548	2	-	26627737	HCT116	viability after 15 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.06024733830528506	[685]	[288,310,520]	0	hSpCas9	negative selection	2129693
73293571	73293594	2	+	26627737	HCT116	viability after 15 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.40859703976174666	[168]	[129,157,98]	4	hSpCas9	negative selection	2129694
73292104	73292127	2	-	26627737	HCT116	viability after 18 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	-1.2472412690439536	[161]	[5,60,29]	-8	hSpCas9	negative selection	2212004
73292441	73292464	2	+	26627737	HCT116	viability after 18 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.6034708957384427	[371]	[197,301,319]	5	hSpCas9	negative selection	2212005
73292668	73292691	2	+	26627737	HCT116	viability after 18 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.601208066481373	[363]	[263,266,269]	5	hSpCas9	negative selection	2212006
73293177	73293200	2	+	26627737	HCT116	viability after 18 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.9781163997153053	[45]	[62,30,37]	7	hSpCas9	negative selection	2212007
73293525	73293548	2	-	26627737	HCT116	viability after 18 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.7043193962326119	[685]	[87,204,322]	-6	hSpCas9	negative selection	2212008
73293571	73293594	2	+	26627737	HCT116	viability after 18 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.5029762556395034	[168]	[155,127,59]	4	hSpCas9	negative selection	2212009
73293168	73293191	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCGCCCTCCTTACCTCCAGGG	EGR4	ENSG00000135625	0.0904871982546871	[5,5]	[3,4]	1	hSpCas9	positive selection	2985293
73293461	73293484	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	-0.6569474487764245	[1,2]	[1,0]	-7	hSpCas9	positive selection	2985294
73293168	73293191	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCGCCCTCCTTACCTCCAGGG	EGR4	ENSG00000135625	0.38933300659167613	[5,5]	[6,3]	6	hSpCas9	positive selection	3053151
73293461	73293484	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	-0.07106520009578476	[1,1]	[2,0]	-1	hSpCas9	positive selection	3053152
73293297	73293320		+	24336571	A375	resistance to PLX after 7 days	AAACTCGCTAAGGTGGAGCATGG	EGR4	ENSG00000135625	-0.5729273656684599	[4,3]	[2,2]	-9	hSpCas9	positive selection	3111486
73292505	73292528		+	24336571	A375	resistance to PLX after 7 days	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	0.2746239304976338	[20,17]	[21,24]	7	hSpCas9	positive selection	3111488
73293273	73293296		+	24336571	A375	resistance to PLX after 7 days	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.09617447545309799	[8,5]	[5,6]	-3	hSpCas9	positive selection	3111489
73293482	73293505		+	24336571	A375	resistance to PLX after 7 days	GCGCCCTCGCTCGCCCGCACCGG	EGR4	ENSG00000135625	-0.12903232797855216	[15,14]	[11,15]	-4	hSpCas9	positive selection	3111490
73293297	73293320		+	24336571	A375	resistance to PLX after 14 days	AAACTCGCTAAGGTGGAGCATGG	EGR4	ENSG00000135625	0.08189719357043312	[4,2]	[1,1]	0	hSpCas9	positive selection	3169279
73292505	73292528		+	24336571	A375	resistance to PLX after 14 days	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	0.12125522344650175	[23,17]	[11,8]	1	hSpCas9	positive selection	3169281
73293273	73293296		+	24336571	A375	resistance to PLX after 14 days	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.3429633844287413	[8,6]	[2,2]	-4	hSpCas9	positive selection	3169282
73293482	73293505		+	24336571	A375	resistance to PLX after 14 days	GCGCCCTCGCTCGCCCGCACCGG	EGR4	ENSG00000135625	-0.6843923568552235	[17,15]	[3,4]	-7	hSpCas9	positive selection	3169283
73293297	73293320		+	24336571	A375	viability after 7 days	AAACTCGCTAAGGTGGAGCATGG	EGR4	ENSG00000135625	0.24611272178220567	[3]	[4,3]	4	hSpCas9	negative selection	3227072
73292505	73292528		+	24336571	A375	viability after 7 days	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	0.21187027390499352	[17]	[20,17]	3	hSpCas9	negative selection	3227074
73293273	73293296		+	24336571	A375	viability after 7 days	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.20522916403129954	[8]	[8,5]	-3	hSpCas9	negative selection	3227075
73293482	73293505		+	24336571	A375	viability after 7 days	GCGCCCTCGCTCGCCCGCACCGG	EGR4	ENSG00000135625	-0.3196145691001291	[20]	[15,14]	-4	hSpCas9	negative selection	3227076
73293297	73293320		+	24336571	A375	viability after 14 days	AAACTCGCTAAGGTGGAGCATGG	EGR4	ENSG00000135625	0.1150326805412174	[3]	[4,2]	1	hSpCas9	negative selection	3284865
73292505	73292528		+	24336571	A375	viability after 14 days	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	0.3202435035593871	[17]	[23,17]	4	hSpCas9	negative selection	3284867
73293273	73293296		+	24336571	A375	viability after 14 days	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.08502156176825848	[8]	[8,6]	-1	hSpCas9	negative selection	3284868
73293482	73293505		+	24336571	A375	viability after 14 days	GCGCCCTCGCTCGCCCGCACCGG	EGR4	ENSG00000135625	-0.1802143114081597	[20]	[17,15]	-2	hSpCas9	negative selection	3284869
73292505	73292528	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.3869542380116674	[208,190]	[0,0]	-2	hSpCas9	positive selection	3347581
73291561	73291584	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.5121627130347508	[72,141]	[0,0]	2	hSpCas9	positive selection	3347582
73293273	73293296	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.7814868362869251	[89,87]	[0,0]	4	hSpCas9	positive selection	3347583
73293222	73293245	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.48914188666890873	[108,108]	[0,0]	2	hSpCas9	positive selection	3366781
73292481	73292504	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	2.3031299010589596	[30,30]	[0,0]	8	hSpCas9	positive selection	3366782
73292623	73292646	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	1.9353981165584726	[199,199]	[4,4]	7	hSpCas9	positive selection	3366783
73292667	73292690	2	-	26780180	HT29	viability (Avana library 4 designs)	CCTCCCGGCCTCAGCTACAGCGG	EGR4	ENSG00000135625	1.16951305622183	[]	[]	4	hSpCas9	negative selection	3422100
73293167	73293190	2	+	26780180	HT29	viability (Avana library 4 designs)	GCTCGCCCTCCTTACCTCCAGGG	EGR4	ENSG00000135625	0.183049529117319	[]	[]	0	hSpCas9	negative selection	3422101
73293460	73293483	2	+	26780180	HT29	viability (Avana library 4 designs)	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	1.96549344382737	[]	[]	7	hSpCas9	negative selection	3422102
73293267	73293290	2	+	26780180	HT29	viability (Avana library 4 designs)	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	0.902458572934862	[]	[]	3	hSpCas9	negative selection	3422103
73293267	73293290	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	-4.61926452562592	[]	[]	-5	hSpCas9	negative selection	3502591
73292667	73292690	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCCCGGCCTCAGCTACAGCGG	EGR4	ENSG00000135625	4.13402664302471	[]	[]	6	hSpCas9	negative selection	3502592
73293460	73293483	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	-0.0710474429592087	[]	[]	0	hSpCas9	negative selection	3502593
73293167	73293190	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCGCCCTCCTTACCTCCAGGG	EGR4	ENSG00000135625	-0.714291514246604	[]	[]	-1	hSpCas9	negative selection	3502594
73293267	73293290	2	+	26780180	A375	viability (Avana lentiGuide)	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	9.94419421965488	[]	[]	7	hSpCas9	negative selection	3611250
73292667	73292690	2	-	26780180	A375	viability (Avana lentiGuide)	CCTCCCGGCCTCAGCTACAGCGG	EGR4	ENSG00000135625	0.966077139556596	[]	[]	1	hSpCas9	negative selection	3611251
73293460	73293483	2	+	26780180	A375	viability (Avana lentiGuide)	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	0.321777409931747	[]	[]	0	hSpCas9	negative selection	3611252
73293167	73293190	2	+	26780180	A375	viability (Avana lentiGuide)	GCTCGCCCTCCTTACCTCCAGGG	EGR4	ENSG00000135625	-0.261570955497838	[]	[]	0	hSpCas9	negative selection	3611253
73293267	73293290	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	-0.45978245760634623	[3]	[2,2]	-6	hSpCas9	positive selection	3719909
73292667	73292690	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCCCGGCCTCAGCTACAGCGG	EGR4	ENSG00000135625	0.18967394036391133	[4]	[5,3]	5	hSpCas9	positive selection	3719910
73293460	73293483	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	-0.030881764679053902	[4]	[3,4]	0	hSpCas9	positive selection	3719911
73293167	73293190	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCGCCCTCCTTACCTCCAGGG	EGR4	ENSG00000135625	-0.11011248453925994	[5]	[4,5]	-2	hSpCas9	positive selection	3719912
73293267	73293290	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	-0.7658208269686382	[4]	[1,2]	-7	hSpCas9	positive selection	3828516
73292667	73292690	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCCCGGCCTCAGCTACAGCGG	EGR4	ENSG00000135625	-1.056225043037717	[5]	[1,1]	-8	hSpCas9	positive selection	3828517
73293460	73293483	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	-0.9296237815801622	[4]	[2,0]	-8	hSpCas9	positive selection	3828518
73293167	73293190	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCGCCCTCCTTACCTCCAGGG	EGR4	ENSG00000135625	0.24036665642036836	[7]	[7,6]	6	hSpCas9	positive selection	3828519
73292505	73292528	2	+	26780180	A375	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	1.22553421218798	[]	[]	6	hSpCas9	negative selection	3935920
73293222	73293245	2	+	26780180	A375	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	1.00877230477362	[]	[]	5	hSpCas9	negative selection	3935921
73293273	73293296	2	+	26780180	A375	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	1.24019194618146	[]	[]	6	hSpCas9	negative selection	3935922
73292481	73292504	2	+	26780180	A375	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	1.16301788157727	[]	[]	6	hSpCas9	negative selection	3935923
73292623	73292646	2	-	26780180	A375	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	1.18696931488843	[]	[]	6	hSpCas9	negative selection	3935924
73291561	73291584	2	+	26780180	A375	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	1.08886967073795	[]	[]	5	hSpCas9	negative selection	3935925
73292505	73292528	2	+	26780180	HT29	viability (GeCKOv2 library)	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	1.58670669392902	[]	[]	8	hSpCas9	negative selection	4043886
73293222	73293245	2	+	26780180	HT29	viability (GeCKOv2 library)	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	1.58651862017155	[]	[]	8	hSpCas9	negative selection	4043887
73293273	73293296	2	+	26780180	HT29	viability (GeCKOv2 library)	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	1.55320469400226	[]	[]	7	hSpCas9	negative selection	4043888
73292481	73292504	2	+	26780180	HT29	viability (GeCKOv2 library)	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	1.04702586331661	[]	[]	5	hSpCas9	negative selection	4043889
73292623	73292646	2	-	26780180	HT29	viability (GeCKOv2 library)	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	1.88950580764899	[]	[]	9	hSpCas9	negative selection	4043890
73291561	73291584	2	+	26780180	HT29	viability (GeCKOv2 library)	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.744068405207253	[]	[]	3	hSpCas9	negative selection	4043891
73293297	73293320	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAACTCGCTAAGGTGGAGCATGG	EGR4	ENSG00000135625	-0.15850724423091145	[1]	[0,0]	-4	hSpCas9	positive selection	4134112
73292505	73292528	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	0.12314243530481636	[4]	[2,3]	3	hSpCas9	positive selection	4134114
73293273	73293296	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.09434251198661986	[2]	[1,1]	-2	hSpCas9	positive selection	4134115
73293482	73293505	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCCCTCGCTCGCCCGCACCGG	EGR4	ENSG00000135625	0.14529304183284303	[3]	[3,2]	4	hSpCas9	positive selection	4134116
73293297	73293320	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAACTCGCTAAGGTGGAGCATGG	EGR4	ENSG00000135625	1.2647660420608018	[1]	[3,2,2,0]	9	hSpCas9	positive selection	4198134
73292505	73292528	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.677800882111383	[3]	[0,0,1,0]	-8	hSpCas9	positive selection	4198136
73293273	73293296	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.5185048402052339	[2]	[0,0,0,0]	-7	hSpCas9	positive selection	4198137
73293482	73293505	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCCCTCGCTCGCCCGCACCGG	EGR4	ENSG00000135625	-0.6600931611091703	[5]	[0,3,1,0]	-8	hSpCas9	positive selection	4198138
73292505	73292528	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	0.006014390262513547	[4]	[4,2]	0	hSpCas9	positive selection	4268346
73291561	73291584	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.11818309251595169	[2]	[2,1]	2	hSpCas9	positive selection	4268347
73293273	73293296	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.22021294939713507	[2]	[2,0]	-4	hSpCas9	positive selection	4268348
73293222	73293245	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.5168895585519047	[2]	[1,0]	-8	hSpCas9	positive selection	4332612
73292481	73292504	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.09525050899661835	[1]	[1,0]	-2	hSpCas9	positive selection	4332613
73292623	73292646	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.18679298199149016	[3]	[3,1]	-4	hSpCas9	positive selection	4332614
73292482	73292504	2	+	27760321	OCIAML3	viability	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.23562090187825202	[191,141]	[154,148]	2	hSpCas9	negative selection	4397016
73292623	73292645	2	-	27760321	OCIAML3	viability	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	0.6188839655459661	[993,773]	[924,1222]	7	hSpCas9	negative selection	4397017
73293223	73293245	2	+	27760321	OCIAML3	viability	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.028766697596044555	[1338,995]	[921,924]	0	hSpCas9	negative selection	4397018
73293269	73293291	2	+	27760321	OCIAML3	viability	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	-0.5005491988707637	[447,427]	[182,319]	-5	hSpCas9	negative selection	4397019
73293291	73293313	2	+	27760321	OCIAML3	viability	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.5696037450285969	[201,154]	[98,85]	-5	hSpCas9	negative selection	4397020
73292482	73292504	2	+	27760321	OCIAML2	viability	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.16465990032583444	[191,141]	[96,148]	-2	hSpCas9	negative selection	4480479
73292623	73292645	2	-	27760321	OCIAML2	viability	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	0.34955427250229065	[993,773]	[777,1071]	5	hSpCas9	negative selection	4480480
73293223	73293245	2	+	27760321	OCIAML2	viability	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.20230355944715384	[1338,995]	[957,1233]	2	hSpCas9	negative selection	4480481
73293269	73293291	2	+	27760321	OCIAML2	viability	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	-0.06113398816942914	[447,427]	[324,359]	-1	hSpCas9	negative selection	4480482
73293291	73293313	2	+	27760321	OCIAML2	viability	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.4020042960823711	[201,154]	[82,141]	-5	hSpCas9	negative selection	4480483
73292482	73292504	2	+	27760321	MV411	viability	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	1.0123939897293923	[191,141]	[348,26]	7	hSpCas9	negative selection	4563942
73292623	73292645	2	-	27760321	MV411	viability	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	0.452971264724203	[993,773]	[541,1169]	3	hSpCas9	negative selection	4563943
73293223	73293245	2	+	27760321	MV411	viability	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.5395924757353172	[1338,995]	[1167,1022]	4	hSpCas9	negative selection	4563944
73293269	73293291	2	+	27760321	MV411	viability	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	-1.3349836224168117	[447,427]	[35,232]	-7	hSpCas9	negative selection	4563945
73293291	73293313	2	+	27760321	MV411	viability	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	0.5167587547253938	[201,154]	[0,416]	4	hSpCas9	negative selection	4563946
73292482	73292504	2	+	27760321	HL60	viability	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.2819042989661129	[191,141]	[192,133]	3	hSpCas9	negative selection	4647405
73292623	73292645	2	-	27760321	HL60	viability	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.40685505604965055	[993,773]	[553,526]	-4	hSpCas9	negative selection	4647406
73293223	73293245	2	+	27760321	HL60	viability	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.1458617884056581	[1338,995]	[1042,1048]	1	hSpCas9	negative selection	4647407
73293269	73293291	2	+	27760321	HL60	viability	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	-0.03297253197788089	[447,427]	[389,307]	0	hSpCas9	negative selection	4647408
73293291	73293313	2	+	27760321	HL60	viability	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.846948206853168	[201,154]	[78,81]	-7	hSpCas9	negative selection	4647409
73292482	73292504	2	+	27760321	HT1080	viability	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	1.474827741345734	[141,110]	[46,241]	7	hSpCas9	negative selection	4730868
73292623	73292645	2	-	27760321	HT1080	viability	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	0.3618389782326612	[773,603]	[409,289]	2	hSpCas9	negative selection	4730869
73293223	73293245	2	+	27760321	HT1080	viability	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	1.422834675742344	[995,776]	[1037,846]	7	hSpCas9	negative selection	4730870
73293269	73293291	2	+	27760321	HT1080	viability	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	-0.7138679102438742	[427,333]	[145,33]	-3	hSpCas9	negative selection	4730871
73293291	73293313	2	+	27760321	HT1080	viability	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-1.5222565306571827	[154,120]	[0,38]	-5	hSpCas9	negative selection	4730872
73292482	73292504	2	+	27760321	HT29	viability after 7 days	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.711695699532235	[141,110]	[96,53,144]	-7	hSpCas9	negative selection	4814331
73292623	73292645	2	-	27760321	HT29	viability after 7 days	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	0.4323640525968073	[773,603]	[1063,1123,1371]	6	hSpCas9	negative selection	4814332
73293223	73293245	2	+	27760321	HT29	viability after 7 days	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.34748058262259973	[995,776]	[1762,1085,1540]	5	hSpCas9	negative selection	4814333
73293269	73293291	2	+	27760321	HT29	viability after 7 days	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	-0.7003165179742238	[427,333]	[235,272,382]	-7	hSpCas9	negative selection	4814334
73293291	73293313	2	+	27760321	HT29	viability after 7 days	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.5486106824022432	[154,120]	[94,143,120]	-7	hSpCas9	negative selection	4814335
73292482	73292504	2	+	27760321	HT29	viability after 25 days	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.7412985522052695	[141,110]	[90,81,85]	-6	hSpCas9	negative selection	4897794
73292623	73292645	2	-	27760321	HT29	viability after 25 days	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	0.544951817871995	[773,603]	[1137,1212,1087]	6	hSpCas9	negative selection	4897795
73293223	73293245	2	+	27760321	HT29	viability after 25 days	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.16047246184053576	[995,776]	[1000,1126,1291]	1	hSpCas9	negative selection	4897796
73293269	73293291	2	+	27760321	HT29	viability after 25 days	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	-0.5254906583225353	[427,333]	[352,289,255]	-5	hSpCas9	negative selection	4897797
73293291	73293313	2	+	27760321	HT29	viability after 25 days	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.6306156511667691	[154,120]	[138,88,71]	-5	hSpCas9	negative selection	4897798
73292482	73292504	2	+	27760321	HT29	viability after 22 days	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.5617244297306597	[141,110]	[375,81,184]	6	hSpCas9	negative selection	4981257
73292623	73292645	2	-	27760321	HT29	viability after 22 days	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	0.592054833248612	[773,603]	[1239,1144,1215]	6	hSpCas9	negative selection	4981258
73293223	73293245	2	+	27760321	HT29	viability after 22 days	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.06300699802675025	[995,776]	[987,1140,1084]	0	hSpCas9	negative selection	4981259
73293269	73293291	2	+	27760321	HT29	viability after 22 days	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	-0.22829299261810293	[427,333]	[473,306,343]	-2	hSpCas9	negative selection	4981260
73293291	73293313	2	+	27760321	HT29	viability after 22 days	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	0.22590122887599895	[154,120]	[415,110,24]	2	hSpCas9	negative selection	4981261
73292482	73292504	2	+	27760321	HT29	viability after 19 days	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-1.7670673903596068	[141,110]	[52,16,57]	-8	hSpCas9	negative selection	5064720
73292623	73292645	2	-	27760321	HT29	viability after 19 days	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	0.6774897621082483	[773,603]	[1431,1589,793]	7	hSpCas9	negative selection	5064721
73293223	73293245	2	+	27760321	HT29	viability after 19 days	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.07914859425755139	[995,776]	[1036,1267,909]	0	hSpCas9	negative selection	5064722
73293269	73293291	2	+	27760321	HT29	viability after 19 days	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	-0.44747451970446994	[427,333]	[216,446,284]	-4	hSpCas9	negative selection	5064723
73293291	73293313	2	+	27760321	HT29	viability after 19 days	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.28305815613918295	[154,120]	[124,118,143]	-3	hSpCas9	negative selection	5064724
73292482	73292504	2	+	27760321	HT29	viability after 16 days	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.03746269638504662	[141,110]	[106,227,94]	0	hSpCas9	negative selection	5148183
73292623	73292645	2	-	27760321	HT29	viability after 16 days	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	0.3355686293583373	[773,603]	[1440,904,617]	4	hSpCas9	negative selection	5148184
73293223	73293245	2	+	27760321	HT29	viability after 16 days	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.12853078635746495	[995,776]	[1261,1131,873]	1	hSpCas9	negative selection	5148185
73293269	73293291	2	+	27760321	HT29	viability after 16 days	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	-0.5121692094763671	[427,333]	[426,248,233]	-5	hSpCas9	negative selection	5148186
73293291	73293313	2	+	27760321	HT29	viability after 16 days	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.6329696391048194	[154,120]	[105,71,121]	-5	hSpCas9	negative selection	5148187
73292482	73292504	2	+	27760321	HT29	viability after 13 days	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.9558676590428443	[141,110]	[31,83,108]	-7	hSpCas9	negative selection	5231646
73292623	73292645	2	-	27760321	HT29	viability after 13 days	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	0.2672659985069967	[773,603]	[1043,988,858]	3	hSpCas9	negative selection	5231647
73293223	73293245	2	+	27760321	HT29	viability after 13 days	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.3623802336200672	[995,776]	[1351,1668,966]	4	hSpCas9	negative selection	5231648
73293269	73293291	2	+	27760321	HT29	viability after 13 days	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	-0.1557623117801667	[427,333]	[298,418,467]	-2	hSpCas9	negative selection	5231649
73293291	73293313	2	+	27760321	HT29	viability after 13 days	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.8947435662302858	[154,120]	[34,95,124]	-7	hSpCas9	negative selection	5231650
73292482	73292504	2	+	27760321	HT29	viability after 10 days	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.17855171714594786	[141,110]	[239,205,92]	2	hSpCas9	negative selection	5315109
73292623	73292645	2	-	27760321	HT29	viability after 10 days	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	0.38084237911458385	[773,603]	[1205,1257,904]	5	hSpCas9	negative selection	5315110
73293223	73293245	2	+	27760321	HT29	viability after 10 days	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.22650143075796492	[995,776]	[1041,1654,1199]	3	hSpCas9	negative selection	5315111
73293269	73293291	2	+	27760321	HT29	viability after 10 days	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	-0.7063313922422741	[427,333]	[353,271,248]	-7	hSpCas9	negative selection	5315112
73293291	73293313	2	+	27760321	HT29	viability after 10 days	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	0.028182502941482612	[154,120]	[70,220,234]	0	hSpCas9	negative selection	5315113
73292482	73292504	2	+	27760321	MOLM13	viability	AGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-1.4204451035066339	[191,141]	[22,44]	-7	hSpCas9	negative selection	5398572
73292623	73292645	2	-	27760321	MOLM13	viability	CCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	1.6908185189655087	[993,773]	[2210,1077]	9	hSpCas9	negative selection	5398573
73293223	73293245	2	+	27760321	MOLM13	viability	AGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.13649365559648752	[1338,995]	[492,908]	0	hSpCas9	negative selection	5398574
73293269	73293291	2	+	27760321	MOLM13	viability	ACTTGACGAGGAGCGCGTCGGG	EGR4	ENSG00000135625	0.4282244900347571	[447,427]	[386,286]	3	hSpCas9	negative selection	5398575
73293291	73293313	2	+	27760321	MOLM13	viability	TTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	1.8500860031243795	[201,154]	[274,432]	9	hSpCas9	negative selection	5398576
73293267	73293290	2	+	27661255	K562	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	0.1423056695010298	[772,811]	[791,617]	5	dCas9-KRAB	negative selection	5476785
73293162	73293185	2	-	27661255	K562	viability	GAGGTAAGGAGGGCGAGCAGGGG	EGR4	ENSG00000135625	0.17612846292383266	[713,779]	[691,656]	6	dCas9-KRAB	negative selection	5476786
73293181	73293204	2	-	27661255	K562	viability	GCGGCCACCGGCTACCCTGGAGG	EGR4	ENSG00000135625	0.10414029843513598	[660,705]	[644,535]	3	dCas9-KRAB	negative selection	5476787
73292505	73292528	2	+	27260156	BXPC3	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.16119380395656613	[1219]	[1018,1028,1096,1469]	-4	hSpCas9	negative selection	5540806
73291561	73291584	2	+	27260156	BXPC3	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.29739596289107906	[376]	[493,400,555,488]	6	hSpCas9	negative selection	5540807
73293273	73293296	2	+	27260156	BXPC3	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.02198324053018208	[285]	[197,347,302,381]	0	hSpCas9	negative selection	5540808
73293222	73293245	2	+	27260156	BXPC3	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.04459513148198191	[237]	[193,197,305,278]	-1	hSpCas9	negative selection	5605072
73292481	73292504	2	+	27260156	BXPC3	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.14082916063905682	[191]	[183,199,278,227]	3	hSpCas9	negative selection	5605073
73292623	73292646	2	-	27260156	BXPC3	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.26650237751800243	[642]	[581,497,580,573]	-6	hSpCas9	negative selection	5605074
73292505	73292528	2	+	27260156	A673	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.3705946790259962	[1219]	[1165,1044,1168,1156]	-7	hSpCas9	negative selection	5662057
73291561	73291584	2	+	27260156	A673	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.0705066987375218	[376]	[656,370,444,449]	1	hSpCas9	negative selection	5662058
73293273	73293296	2	+	27260156	A673	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.057635583171730675	[285]	[342,363,300,310]	-1	hSpCas9	negative selection	5662059
73293222	73293245	2	+	27260156	A673	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.07463031394260966	[237]	[338,232,263,256]	-2	hSpCas9	negative selection	5726323
73292481	73292504	2	+	27260156	A673	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.34379033002642667	[191]	[216,189,148,173]	-7	hSpCas9	negative selection	5726324
73292623	73292646	2	-	27260156	A673	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.5551889278457435	[642]	[633,550,500,420]	-8	hSpCas9	negative selection	5726325
73292505	73292528	2	+	27260156	A375	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.15627306942955	[1219]	[1265,1755,1263,931]	-2	hSpCas9	negative selection	5783308
73291561	73291584	2	+	27260156	A375	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	-0.04835338896529251	[376]	[272,636,496,333]	0	hSpCas9	negative selection	5783309
73293273	73293296	2	+	27260156	A375	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.0491395911223762	[285]	[306,234,334,472]	0	hSpCas9	negative selection	5783310
73293222	73293245	2	+	27260156	A375	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.21720186067188263	[237]	[251,348,227,449]	3	hSpCas9	negative selection	5847574
73292481	73292504	2	+	27260156	A375	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.5444508881240524	[191]	[215,128,126,140]	-6	hSpCas9	negative selection	5847575
73292623	73292646	2	-	27260156	A375	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.27585259804704687	[642]	[565,942,455,564]	-4	hSpCas9	negative selection	5847576
73292505	73292528	2	+	27260156	COLO741	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.2544729926339575	[1219]	[1427,1285,1219]	-5	hSpCas9	negative selection	5904559
73291561	73291584	2	+	27260156	COLO741	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.27836775425448035	[376]	[540,639,567]	6	hSpCas9	negative selection	5904560
73293273	73293296	2	+	27260156	COLO741	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.03696373074613446	[285]	[420,349,357]	0	hSpCas9	negative selection	5904561
73293222	73293245	2	+	27260156	COLO741	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.006160966348359831	[237]	[310,313,291]	0	hSpCas9	negative selection	5968825
73292481	73292504	2	+	27260156	COLO741	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.2771118563597501	[191]	[152,277,173]	-5	hSpCas9	negative selection	5968826
73292623	73292646	2	-	27260156	COLO741	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.3940875978622637	[642]	[593,713,567]	-7	hSpCas9	negative selection	5968827
73292505	73292528	2	+	27260156	CAL120	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.3051981480027932	[1219]	[1058,1426,1174]	-4	hSpCas9	negative selection	6025810
73291561	73291584	2	+	27260156	CAL120	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.19165531590155974	[376]	[447,781,366]	3	hSpCas9	negative selection	6025811
73293273	73293296	2	+	27260156	CAL120	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.08867376917581649	[285]	[426,267,322]	-1	hSpCas9	negative selection	6025812
73293222	73293245	2	+	27260156	CAL120	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.1466194682719124	[237]	[278,243,280]	-2	hSpCas9	negative selection	6090076
73292481	73292504	2	+	27260156	CAL120	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.14711181905202486	[191]	[296,209,290]	2	hSpCas9	negative selection	6090077
73292623	73292646	2	-	27260156	CAL120	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.4175132060447624	[642]	[741,617,460]	-6	hSpCas9	negative selection	6090078
73292505	73292528	2	+	27260156	CADOES1	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.24988502457604755	[1219]	[1208,774,1026,798]	-4	hSpCas9	negative selection	6147061
73291561	73291584	2	+	27260156	CADOES1	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.3411162736413449	[376]	[412,491,371,501]	6	hSpCas9	negative selection	6147062
73293273	73293296	2	+	27260156	CADOES1	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.0017783370409887311	[285]	[258,212,262,329]	0	hSpCas9	negative selection	6147063
73293222	73293245	2	+	27260156	CADOES1	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.10950424166358697	[237]	[293,170,198,292]	2	hSpCas9	negative selection	6211327
73292481	73292504	2	+	27260156	CADOES1	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.0563496884289465	[191]	[305,121,161,150]	1	hSpCas9	negative selection	6211328
73292623	73292646	2	-	27260156	CADOES1	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.4469951342166831	[642]	[582,355,382,431]	-7	hSpCas9	negative selection	6211329
73292505	73292528	2	+	27260156	EWS502	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.4706313050973293	[1219]	[626,939,960,1258]	-7	hSpCas9	negative selection	6268312
73291561	73291584	2	+	27260156	EWS502	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.3012725697102923	[376]	[462,440,400,678]	5	hSpCas9	negative selection	6268313
73293273	73293296	2	+	27260156	EWS502	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.25862328745125207	[285]	[194,185,333,311]	-4	hSpCas9	negative selection	6268314
73293222	73293245	2	+	27260156	EWS502	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.05874976429007983	[237]	[203,277,187,303]	-1	hSpCas9	negative selection	6332578
73292481	73292504	2	+	27260156	EWS502	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.29003919838045533	[191]	[163,140,200,159]	-5	hSpCas9	negative selection	6332579
73292623	73292646	2	-	27260156	EWS502	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.8032388464500947	[642]	[280,510,399,374]	-8	hSpCas9	negative selection	6332580
73292505	73292528	2	+	27260156	EW8	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.483748893391727	[1219]	[864,822,639,527]	-7	hSpCas9	negative selection	6389563
73291561	73291584	2	+	27260156	EW8	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.08408680141097169	[376]	[284,483,187,356]	1	hSpCas9	negative selection	6389564
73293273	73293296	2	+	27260156	EW8	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.31909032729869324	[285]	[234,437,185,308]	6	hSpCas9	negative selection	6389565
73293222	73293245	2	+	27260156	EW8	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.0227179145843025	[237]	[207,233,98,259]	0	hSpCas9	negative selection	6453829
73292481	73292504	2	+	27260156	EW8	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.12870755274125956	[191]	[242,148,89,106]	-2	hSpCas9	negative selection	6453830
73292623	73292646	2	-	27260156	EW8	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.5746426530999053	[642]	[485,298,322,309]	-8	hSpCas9	negative selection	6453831
73292505	73292528	2	+	27260156	CORL105	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.1914410676569145	[1219]	[1071,1326,1428,1194]	-4	hSpCas9	negative selection	6510814
73291561	73291584	2	+	27260156	CORL105	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.18852202782854283	[376]	[478,570,429,517]	3	hSpCas9	negative selection	6510815
73293273	73293296	2	+	27260156	CORL105	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.4165387009481568	[285]	[675,281,410,423]	7	hSpCas9	negative selection	6510816
73293222	73293245	2	+	27260156	CORL105	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.16713965915415718	[237]	[211,218,325,246]	-3	hSpCas9	negative selection	6575080
73292481	73292504	2	+	27260156	CORL105	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.2803653743244554	[191]	[355,158,367,228]	5	hSpCas9	negative selection	6575081
73292623	73292646	2	-	27260156	CORL105	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.4227682768473404	[642]	[520,742,488,476]	-6	hSpCas9	negative selection	6575082
73292505	73292528	2	+	27260156	HS294T	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.13056209385363382	[1219]	[345,264,384,801]	-2	hSpCas9	negative selection	6632065
73291561	73291584	2	+	27260156	HS294T	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	-0.10274676534835542	[376]	[95,143,135,176]	-1	hSpCas9	negative selection	6632066
73293273	73293296	2	+	27260156	HS294T	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.6153644336878734	[285]	[39,79,110,57]	-7	hSpCas9	negative selection	6632067
73293222	73293245	2	+	27260156	HS294T	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.5828585553467394	[237]	[47,59,61,79]	-7	hSpCas9	negative selection	6696331
73292481	73292504	2	+	27260156	HS294T	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.7048537399078298	[191]	[37,35,58,50]	-7	hSpCas9	negative selection	6696332
73292623	73292646	2	-	27260156	HS294T	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.5969879806576607	[642]	[122,141,150,261]	-7	hSpCas9	negative selection	6696333
73292505	73292528	2	+	27260156	HCC44	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.3611677176151462	[1219]	[1028,747,1222,1346]	-5	hSpCas9	negative selection	6753316
73291561	73291584	2	+	27260156	HCC44	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.3000228686756327	[376]	[514,615,480,463]	5	hSpCas9	negative selection	6753317
73293273	73293296	2	+	27260156	HCC44	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.17737982949616982	[285]	[240,249,339,319]	-3	hSpCas9	negative selection	6753318
73293222	73293245	2	+	27260156	HCC44	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.35455511138617	[237]	[241,260,175,152]	-5	hSpCas9	negative selection	6817582
73292481	73292504	2	+	27260156	HCC44	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.1338629001782028	[191]	[310,174,126,178]	-2	hSpCas9	negative selection	6817583
73292623	73292646	2	-	27260156	HCC44	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.9230964666643101	[642]	[266,335,473,462]	-8	hSpCas9	negative selection	6817584
73292505	73292528	2	+	27260156	G402	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.6833058590678299	[1219]	[863,860,1132,837]	-7	hSpCas9	negative selection	6874567
73291561	73291584	2	+	27260156	G402	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	-0.051588300770967155	[376]	[336,447,539,433]	0	hSpCas9	negative selection	6874568
73293273	73293296	2	+	27260156	G402	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.09440979974724184	[285]	[285,439,213,364]	-1	hSpCas9	negative selection	6874569
73293222	73293245	2	+	27260156	G402	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.20295876233534893	[237]	[182,593,364,193]	2	hSpCas9	negative selection	6938833
73292481	73292504	2	+	27260156	G402	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.10961043005349835	[191]	[164,425,120,162]	-1	hSpCas9	negative selection	6938834
73292623	73292646	2	-	27260156	G402	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.767819162397648	[642]	[620,385,409,443]	-7	hSpCas9	negative selection	6938835
73292505	73292528	2	+	27260156	L33	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.1149458409243227	[1219]	[1011,545,712,1030]	-3	hSpCas9	negative selection	6995818
73291561	73291584	2	+	27260156	L33	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	-0.13413097497544896	[376]	[332,153,201,343]	-3	hSpCas9	negative selection	6995819
73293273	73293296	2	+	27260156	L33	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.36545106425423457	[285]	[208,80,154,234]	-7	hSpCas9	negative selection	6995820
73293222	73293245	2	+	27260156	L33	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.1085770914609342	[237]	[291,96,142,268]	2	hSpCas9	negative selection	7060084
73292481	73292504	2	+	27260156	L33	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.17870437250930582	[191]	[117,82,125,158]	-4	hSpCas9	negative selection	7060085
73292623	73292646	2	-	27260156	L33	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.3206874782037392	[642]	[496,218,291,562]	-6	hSpCas9	negative selection	7060086
73292505	73292528	2	+	27260156	K562	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.35249736588485314	[1219]	[621,639,759,1284]	-4	hSpCas9	negative selection	7117069
73291561	73291584	2	+	27260156	K562	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.35654011772395067	[376]	[361,538,514,309]	4	hSpCas9	negative selection	7117070
73293273	73293296	2	+	27260156	K562	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.17556934706603133	[285]	[235,115,116,402]	-2	hSpCas9	negative selection	7117071
73293222	73293245	2	+	27260156	K562	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.3692125219923821	[237]	[239,175,220,426]	4	hSpCas9	negative selection	7181335
73292481	73292504	2	+	27260156	K562	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.07158558746269672	[191]	[157,294,128,81]	-1	hSpCas9	negative selection	7181336
73292623	73292646	2	-	27260156	K562	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.8129810124259107	[642]	[477,395,189,257]	-7	hSpCas9	negative selection	7181337
73292505	73292528	2	+	27260156	HT29	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.2798816523068015	[1219]	[1189,1653,1071,1020]	-5	hSpCas9	negative selection	7238320
73291561	73291584	2	+	27260156	HT29	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.2702395043329139	[376]	[780,469,644,346]	5	hSpCas9	negative selection	7238321
73293273	73293296	2	+	27260156	HT29	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.2582327668367166	[285]	[336,302,357,180]	-5	hSpCas9	negative selection	7238322
73293222	73293245	2	+	27260156	HT29	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.1074322902767566	[237]	[311,290,299,184]	-2	hSpCas9	negative selection	7302586
73292481	73292504	2	+	27260156	HT29	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.5588476058545373	[191]	[110,138,278,104]	-7	hSpCas9	negative selection	7302587
73292623	73292646	2	-	27260156	HT29	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.15583030297770023	[642]	[654,736,771,643]	-3	hSpCas9	negative selection	7302588
73292505	73292528	2	+	27260156	MHHES1	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.43191162589247956	[1219]	[1149,1444,891,697]	-7	hSpCas9	negative selection	7359571
73291561	73291584	2	+	27260156	MHHES1	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.06040876505201359	[376]	[681,430,205,462]	1	hSpCas9	negative selection	7359572
73293273	73293296	2	+	27260156	MHHES1	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.054859837044481496	[285]	[428,366,301,184]	-1	hSpCas9	negative selection	7359573
73293222	73293245	2	+	27260156	MHHES1	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.22379491366413806	[237]	[350,348,256,298]	4	hSpCas9	negative selection	7423837
73292481	73292504	2	+	27260156	MHHES1	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.3001596236853328	[191]	[136,195,192,170]	-5	hSpCas9	negative selection	7423838
73292623	73292646	2	-	27260156	MHHES1	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.6933850850040356	[642]	[631,488,454,272]	-8	hSpCas9	negative selection	7423839
73292505	73292528	2	+	27260156	MEWO	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.31125023924456063	[1219]	[1217,760,838]	-6	hSpCas9	negative selection	7480822
73291561	73291584	2	+	27260156	MEWO	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.16398567530336333	[376]	[447,321,425]	3	hSpCas9	negative selection	7480823
73293273	73293296	2	+	27260156	MEWO	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.18179639081626053	[285]	[234,338,322]	4	hSpCas9	negative selection	7480824
73293222	73293245	2	+	27260156	MEWO	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.011572052663768151	[237]	[262,180,236]	0	hSpCas9	negative selection	7545088
73292481	73292504	2	+	27260156	MEWO	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.4171945591429964	[191]	[120,115,163]	-7	hSpCas9	negative selection	7545089
73292623	73292646	2	-	27260156	MEWO	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.15182849724017017	[642]	[484,410,717]	-3	hSpCas9	negative selection	7545090
73292505	73292528	2	+	27260156	LNCAPCLONEFGC	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	0.05983801549342216	[1219]	[844,1259,1105,1387]	0	hSpCas9	negative selection	7602073
73291561	73291584	2	+	27260156	LNCAPCLONEFGC	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.08767851159406467	[376]	[346,327,490,306]	1	hSpCas9	negative selection	7602074
73293273	73293296	2	+	27260156	LNCAPCLONEFGC	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.06116992957526002	[285]	[280,271,258,266]	0	hSpCas9	negative selection	7602075
73293222	73293245	2	+	27260156	LNCAPCLONEFGC	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.21261698201034518	[237]	[240,239,148,354]	3	hSpCas9	negative selection	7666339
73292481	73292504	2	+	27260156	LNCAPCLONEFGC	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.08248080541046954	[191]	[160,127,273,190]	1	hSpCas9	negative selection	7666340
73292623	73292646	2	-	27260156	LNCAPCLONEFGC	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.25825515710977076	[642]	[499,462,513,475]	-4	hSpCas9	negative selection	7666341
73292505	73292528	2	+	27260156	PANC0327	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	0.15531446769447887	[1219]	[995,1609,1142,1008]	2	hSpCas9	negative selection	7723324
73291561	73291584	2	+	27260156	PANC0327	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.8090656529556581	[376]	[429,969,284,598]	9	hSpCas9	negative selection	7723325
73293273	73293296	2	+	27260156	PANC0327	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.04938419137758743	[285]	[129,358,310,157]	0	hSpCas9	negative selection	7723326
73293222	73293245	2	+	27260156	PANC0327	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.16369688503711277	[237]	[120,175,213,239]	-2	hSpCas9	negative selection	7787590
73292481	73292504	2	+	27260156	PANC0327	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.6257377598487566	[191]	[103,74,56,209]	-7	hSpCas9	negative selection	7787591
73292623	73292646	2	-	27260156	PANC0327	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.31885272606324877	[642]	[436,416,428,551]	-5	hSpCas9	negative selection	7787592
73292505	73292528	2	+	27260156	NCIH2009	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.2099458495732811	[1219]	[1798,1575,1105]	-3	hSpCas9	negative selection	7844575
73291561	73291584	2	+	27260156	NCIH2009	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	-0.02271426764193729	[376]	[495,527,525]	0	hSpCas9	negative selection	7844576
73293273	73293296	2	+	27260156	NCIH2009	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.10094264802569108	[285]	[519,482,298]	1	hSpCas9	negative selection	7844577
73293222	73293245	2	+	27260156	NCIH2009	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.11439221874281258	[237]	[324,170,430]	-1	hSpCas9	negative selection	7908841
73292481	73292504	2	+	27260156	NCIH2009	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.3391550238289436	[191]	[140,198,281]	-4	hSpCas9	negative selection	7908842
73292623	73292646	2	-	27260156	NCIH2009	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.5123963221744829	[642]	[853,721,354]	-6	hSpCas9	negative selection	7908843
73292505	73292528	2	+	27260156	NCIH1373	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.5316493359138919	[1219]	[930,942,758,304]	-5	hSpCas9	negative selection	7965826
73291561	73291584	2	+	27260156	NCIH1373	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.8453938137166142	[376]	[510,629,797,285]	8	hSpCas9	negative selection	7965827
73293273	73293296	2	+	27260156	NCIH1373	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-1.0178530823108118	[285]	[146,160,151,44]	-8	hSpCas9	negative selection	7965828
73293222	73293245	2	+	27260156	NCIH1373	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.04780184290537104	[237]	[423,153,161,87]	0	hSpCas9	negative selection	8030092
73292481	73292504	2	+	27260156	NCIH1373	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.5050893317608542	[191]	[241,119,151,27]	-5	hSpCas9	negative selection	8030093
73292623	73292646	2	-	27260156	NCIH1373	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-1.0818795022229668	[642]	[473,397,191,81]	-8	hSpCas9	negative selection	8030094
73292505	73292528	2	+	27260156	PATU8902	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.21298493884463388	[1219]	[1425,1586,853,2236]	-2	hSpCas9	negative selection	8087077
73291561	73291584	2	+	27260156	PATU8902	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.49450402521261827	[376]	[746,369,699,1199]	5	hSpCas9	negative selection	8087078
73293273	73293296	2	+	27260156	PATU8902	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.1776005031420218	[285]	[148,525,557,553]	1	hSpCas9	negative selection	8087079
73293222	73293245	2	+	27260156	PATU8902	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.8772393929021731	[237]	[123,332,111,168]	-7	hSpCas9	negative selection	8151343
73292481	73292504	2	+	27260156	PATU8902	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.07186883837208913	[191]	[112,390,251,388]	0	hSpCas9	negative selection	8151344
73292623	73292646	2	-	27260156	PATU8902	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.18455926976888598	[642]	[1152,932,542,546]	-2	hSpCas9	negative selection	8151345
73292505	73292528	2	+	27260156	PANC1	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.13386255453512796	[1219]	[628,1103,1198,917]	-2	hSpCas9	negative selection	8208328
73291561	73291584	2	+	27260156	PANC1	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.2141095789419188	[376]	[258,484,319,444]	3	hSpCas9	negative selection	8208329
73293273	73293296	2	+	27260156	PANC1	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.1648961247654338	[285]	[143,406,218,153]	-3	hSpCas9	negative selection	8208330
73293222	73293245	2	+	27260156	PANC1	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.07067966836000372	[237]	[203,287,136,236]	1	hSpCas9	negative selection	8272594
73292481	73292504	2	+	27260156	PANC1	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.29940906503318	[191]	[66,118,114,216]	-5	hSpCas9	negative selection	8272595
73292623	73292646	2	-	27260156	PANC1	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.532586316970727	[642]	[257,568,453,295]	-7	hSpCas9	negative selection	8272596
73292505	73292528	2	+	27260156	PANC0813	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.06017422896896463	[1219]	[1358,1375,1154,1590]	-1	hSpCas9	negative selection	8329579
73291561	73291584	2	+	27260156	PANC0813	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.388699131912525	[376]	[741,442,582,565]	6	hSpCas9	negative selection	8329580
73293273	73293296	2	+	27260156	PANC0813	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.07254025616624482	[285]	[346,399,333,331]	1	hSpCas9	negative selection	8329581
73293222	73293245	2	+	27260156	PANC0813	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.09680713990489265	[237]	[245,368,287,287]	1	hSpCas9	negative selection	8393845
73292481	73292504	2	+	27260156	PANC0813	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.18740774939083327	[191]	[280,149,297,297]	3	hSpCas9	negative selection	8393846
73292623	73292646	2	-	27260156	PANC0813	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.21687350237801864	[642]	[759,796,480,573]	-3	hSpCas9	negative selection	8393847
73292505	73292528	2	+	27260156	RDES	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.3185155058310465	[1219]	[1039,1091,1096,1277]	-5	hSpCas9	negative selection	8450830
73291561	73291584	2	+	27260156	RDES	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.2096678131891591	[376]	[473,377,536,640]	3	hSpCas9	negative selection	8450831
73293273	73293296	2	+	27260156	RDES	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.22802479715111013	[285]	[209,238,259,450]	-4	hSpCas9	negative selection	8450832
73293222	73293245	2	+	27260156	RDES	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.3230185537270329	[237]	[248,193,230,183]	-5	hSpCas9	negative selection	8515096
73292481	73292504	2	+	27260156	RDES	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.07043173258927382	[191]	[205,162,149,337]	-1	hSpCas9	negative selection	8515097
73292623	73292646	2	-	27260156	RDES	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.5087898712207345	[642]	[494,485,555,536]	-7	hSpCas9	negative selection	8515098
73292505	73292528	2	+	27260156	PC3	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.13362311077095623	[1219]	[843,922,1823,1120]	-3	hSpCas9	negative selection	8572081
73291561	73291584	2	+	27260156	PC3	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	-0.24793101363672637	[376]	[249,327,465,267]	-5	hSpCas9	negative selection	8572082
73293273	73293296	2	+	27260156	PC3	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.1433062092164188	[285]	[145,173,482,352]	-3	hSpCas9	negative selection	8572083
73293222	73293245	2	+	27260156	PC3	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.42764444465230844	[237]	[180,464,296,347]	8	hSpCas9	negative selection	8636347
73292481	73292504	2	+	27260156	PC3	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.1740355097874582	[191]	[77,245,354,90]	-4	hSpCas9	negative selection	8636348
73292623	73292646	2	-	27260156	PC3	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.5669760605432498	[642]	[334,354,763,400]	-8	hSpCas9	negative selection	8636349
73292505	73292528	2	+	27260156	PATU8988T	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.34917821919067427	[1219]	[897,982,728,1114]	-5	hSpCas9	negative selection	8693332
73291561	73291584	2	+	27260156	PATU8988T	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.7517905078152858	[376]	[518,650,792,480]	9	hSpCas9	negative selection	8693333
73293273	73293296	2	+	27260156	PATU8988T	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.15425916201463907	[285]	[412,231,137,206]	-3	hSpCas9	negative selection	8693334
73293222	73293245	2	+	27260156	PATU8988T	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.339457062214927	[237]	[300,167,390,290]	6	hSpCas9	negative selection	8757598
73292481	73292504	2	+	27260156	PATU8988T	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	0.7122345598308156	[191]	[229,386,317,286]	9	hSpCas9	negative selection	8757599
73292623	73292646	2	-	27260156	PATU8988T	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.4018221970105827	[642]	[414,541,273,675]	-6	hSpCas9	negative selection	8757600
73292505	73292528	2	+	27260156	T47D	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.21952294318546128	[1219]	[1268,1130,1197,1294]	-5	hSpCas9	negative selection	8814583
73291561	73291584	2	+	27260156	T47D	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.09716262356241648	[376]	[541,419,369,555]	2	hSpCas9	negative selection	8814584
73293273	73293296	2	+	27260156	T47D	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.08514905882041679	[285]	[473,268,344,332]	1	hSpCas9	negative selection	8814585
73293222	73293245	2	+	27260156	T47D	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.17174706339855206	[237]	[333,279,261,378]	3	hSpCas9	negative selection	8878849
73292481	73292504	2	+	27260156	T47D	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.06871579177174825	[191]	[234,226,186,202]	-1	hSpCas9	negative selection	8878850
73292623	73292646	2	-	27260156	T47D	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.5003855801212547	[642]	[534,572,457,549]	-8	hSpCas9	negative selection	8878851
73292505	73292528	2	+	27260156	SU8686	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.02954646005575179	[1219]	[1316,925,1137,1402]	0	hSpCas9	negative selection	8935834
73291561	73291584	2	+	27260156	SU8686	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.20188161770887278	[376]	[370,359,477,542]	3	hSpCas9	negative selection	8935835
73293273	73293296	2	+	27260156	SU8686	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.3312195842516813	[285]	[298,303,519,311]	5	hSpCas9	negative selection	8935836
73293222	73293245	2	+	27260156	SU8686	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.4174081195806678	[237]	[248,294,318,422]	7	hSpCas9	negative selection	9000100
73292481	73292504	2	+	27260156	SU8686	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.7890365420939198	[191]	[73,132,138,92]	-8	hSpCas9	negative selection	9000101
73292623	73292646	2	-	27260156	SU8686	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.5988893447004515	[642]	[411,373,527,367]	-7	hSpCas9	negative selection	9000102
73292505	73292528	2	+	27260156	SKES1	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.2619974958403599	[1219]	[1010,1174,1040,858]	-5	hSpCas9	negative selection	9057085
73291561	73291584	2	+	27260156	SKES1	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.019400944003082343	[376]	[543,400,286,321]	0	hSpCas9	negative selection	9057086
73293273	73293296	2	+	27260156	SKES1	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.3239705614739258	[285]	[516,328,303,300]	6	hSpCas9	negative selection	9057087
73293222	73293245	2	+	27260156	SKES1	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.0033619381871838883	[237]	[290,324,197,158]	0	hSpCas9	negative selection	9121351
73292481	73292504	2	+	27260156	SKES1	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.4270697645157131	[191]	[247,185,55,103]	-7	hSpCas9	negative selection	9121352
73292623	73292646	2	-	27260156	SKES1	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.3771636975146989	[642]	[434,561,485,487]	-7	hSpCas9	negative selection	9121353
73292505	73292528	2	+	27260156	TOV112D	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.23586102790348873	[1219]	[922,1413,1158,743]	-4	hSpCas9	negative selection	9178336
73291561	73291584	2	+	27260156	TOV112D	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.1717457530482934	[376]	[577,432,484,224]	3	hSpCas9	negative selection	9178337
73293273	73293296	2	+	27260156	TOV112D	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.2162568478762913	[285]	[436,368,201,339]	4	hSpCas9	negative selection	9178338
73293222	73293245	2	+	27260156	TOV112D	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.38176182826360594	[237]	[236,223,96,187]	-6	hSpCas9	negative selection	9242602
73292481	73292504	2	+	27260156	TOV112D	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.5286135736345607	[191]	[199,126,146,64]	-8	hSpCas9	negative selection	9242603
73292623	73292646	2	-	27260156	TOV112D	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.9241647210696804	[642]	[358,340,210,444]	-9	hSpCas9	negative selection	9242604
73292505	73292528	2	+	27260156	TC71	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.42336224228459884	[1219]	[877,1079,919,1029]	-8	hSpCas9	negative selection	9299587
73291561	73291584	2	+	27260156	TC71	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.10582159095086377	[376]	[510,383,414,427]	2	hSpCas9	negative selection	9299588
73293273	73293296	2	+	27260156	TC71	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	-0.00031396870860767034	[285]	[315,300,251,361]	0	hSpCas9	negative selection	9299589
73293222	73293245	2	+	27260156	TC71	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.3241188281444305	[237]	[157,185,157,322]	-7	hSpCas9	negative selection	9363853
73292481	73292504	2	+	27260156	TC71	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.527143668915546	[191]	[113,162,137,157]	-9	hSpCas9	negative selection	9363854
73292623	73292646	2	-	27260156	TC71	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.5036657338429233	[642]	[441,395,479,636]	-8	hSpCas9	negative selection	9363855
73292505	73292528	2	+	27260156	TC32	viability	AGCAAGGCATCGGACCCCGCAGG	EGR4	ENSG00000135625	-0.19955923379305762	[1219]	[907,910,1286,913]	-4	hSpCas9	negative selection	9420838
73291561	73291584	2	+	27260156	TC32	viability	TCTCATCGCTGCGCGCGAAGCGG	EGR4	ENSG00000135625	0.33348064675195266	[376]	[408,345,528,536]	6	hSpCas9	negative selection	9420839
73293273	73293296	2	+	27260156	TC32	viability	GACGAGGAGCGCGTCGGGTTCGG	EGR4	ENSG00000135625	0.04116055658579898	[285]	[336,169,333,291]	0	hSpCas9	negative selection	9420840
73293222	73293245	2	+	27260156	TC32	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.027045857336546186	[237]	[200,130,305,319]	0	hSpCas9	negative selection	9485104
73292481	73292504	2	+	27260156	TC32	viability	GAGTAAAGGTCCGGCGGACCCGG	EGR4	ENSG00000135625	-0.14998946454714468	[191]	[84,175,245,151]	-3	hSpCas9	negative selection	9485105
73292623	73292646	2	-	27260156	TC32	viability	GCCCGAACACCCGCACGACCCGG	EGR4	ENSG00000135625	-0.3062247447159324	[642]	[373,418,600,597]	-5	hSpCas9	negative selection	9485106
73292104	73292127	2	-	27869803	HPAFII	viability after 27 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	0.12245938315029714	[87]	[27,68,NaN]	1	hSpCas9	negative selection	9575709
73292441	73292464	2	+	27869803	HPAFII	viability after 27 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.1461495159965014	[632]	[448,300,NaN]	1	hSpCas9	negative selection	9575710
73292668	73292691	2	+	27869803	HPAFII	viability after 27 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.9454126978016213	[306]	[438,203,NaN]	7	hSpCas9	negative selection	9575711
73293177	73293200	2	+	27869803	HPAFII	viability after 27 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-0.3723053085992807	[61]	[34,16,NaN]	-3	hSpCas9	negative selection	9575712
73293525	73293548	2	-	27869803	HPAFII	viability after 27 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	0.2982238342960938	[458]	[347,253,NaN]	2	hSpCas9	negative selection	9575713
73293571	73293594	2	+	27869803	HPAFII	viability after 27 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.7066520693486157	[193]	[160,170,NaN]	6	hSpCas9	negative selection	9575714
73292104	73292127	2	-	27869803	HPAFII	viability after 15 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	0.30246396066313674	[87]	[144,98,NaN]	3	hSpCas9	negative selection	9658158
73292441	73292464	2	+	27869803	HPAFII	viability after 15 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	-0.04808832569689492	[632]	[850,537,NaN]	0	hSpCas9	negative selection	9658159
73292668	73292691	2	+	27869803	HPAFII	viability after 15 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.7454813165711567	[306]	[472,602,NaN]	8	hSpCas9	negative selection	9658160
73293177	73293200	2	+	27869803	HPAFII	viability after 15 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.5304513500575339	[61]	[205,27,NaN]	6	hSpCas9	negative selection	9658161
73293525	73293548	2	-	27869803	HPAFII	viability after 15 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	0.3240573809987747	[458]	[656,592,NaN]	4	hSpCas9	negative selection	9658162
73293571	73293594	2	+	27869803	HPAFII	viability after 15 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.6882558058784216	[193]	[433,274,NaN]	7	hSpCas9	negative selection	9658163
73292104	73292127	2	-	27869803	ASPC1	viability after 36 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	-1.7987011010678784	[274]	[30,29,22]	-9	hSpCas9	negative selection	9740607
73292441	73292464	2	+	27869803	ASPC1	viability after 36 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.2772444223603545	[1288]	[481,708,453]	2	hSpCas9	negative selection	9740608
73292668	73292691	2	+	27869803	ASPC1	viability after 36 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	-0.6169405708197662	[861]	[206,109,254]	-6	hSpCas9	negative selection	9740609
73293177	73293200	2	+	27869803	ASPC1	viability after 36 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	1.2585530154340863	[238]	[63,47,412]	9	hSpCas9	negative selection	9740610
73293525	73293548	2	-	27869803	ASPC1	viability after 36 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.10464332419088485	[1601]	[502,831,278]	-1	hSpCas9	negative selection	9740611
73293571	73293594	2	+	27869803	ASPC1	viability after 36 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.5651152678803446	[651]	[292,197,473]	5	hSpCas9	negative selection	9740612
73292104	73292127	2	-	27869803	PATU8988S	viability after 35 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	0.1956654518569101	[181]	[60,106,NaN]	2	hSpCas9	negative selection	9823056
73292441	73292464	2	+	27869803	PATU8988S	viability after 35 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.5845505948571166	[1152]	[633,758,NaN]	6	hSpCas9	negative selection	9823057
73292668	73292691	2	+	27869803	PATU8988S	viability after 35 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	-0.2919301963822391	[698]	[207,251,NaN]	-3	hSpCas9	negative selection	9823058
73293177	73293200	2	+	27869803	PATU8988S	viability after 35 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.3570591705434448	[255]	[156,106,NaN]	4	hSpCas9	negative selection	9823059
73293525	73293548	2	-	27869803	PATU8988S	viability after 35 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.4377489793872825	[1281]	[247,514,NaN]	-4	hSpCas9	negative selection	9823060
73293571	73293594	2	+	27869803	PATU8988S	viability after 35 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.830923055814091	[500]	[326,390,NaN]	8	hSpCas9	negative selection	9823061
73292104	73292127	2	-	27869803	PATU8988S	viability after 31 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	0.1802881515797723	[181]	[39,135,NaN]	2	hSpCas9	negative selection	9905505
73292441	73292464	2	+	27869803	PATU8988S	viability after 31 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.4146066556646466	[1152]	[508,744,NaN]	5	hSpCas9	negative selection	9905506
73292668	73292691	2	+	27869803	PATU8988S	viability after 31 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.26852559649880187	[698]	[245,449,NaN]	3	hSpCas9	negative selection	9905507
73293177	73293200	2	+	27869803	PATU8988S	viability after 31 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	1.0674296187346566	[255]	[238,181,NaN]	9	hSpCas9	negative selection	9905508
73293525	73293548	2	-	27869803	PATU8988S	viability after 31 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	-0.47754236481837786	[1281]	[250,514,NaN]	-5	hSpCas9	negative selection	9905509
73293571	73293594	2	+	27869803	PATU8988S	viability after 31 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.9472031419275836	[500]	[305,485,NaN]	9	hSpCas9	negative selection	9905510
73292104	73292127	2	-	27869803	HPAFII	viability after 35 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	-0.9803038257509837	[87]	[7,38,NaN]	-5	hSpCas9	negative selection	9987954
73292441	73292464	2	+	27869803	HPAFII	viability after 35 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.37054648616614183	[632]	[537,274,NaN]	2	hSpCas9	negative selection	9987955
73292668	73292691	2	+	27869803	HPAFII	viability after 35 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.3038866209706818	[306]	[260,113,NaN]	2	hSpCas9	negative selection	9987956
73293177	73293200	2	+	27869803	HPAFII	viability after 35 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.25815480616343267	[61]	[53,18,NaN]	1	hSpCas9	negative selection	9987957
73293525	73293548	2	-	27869803	HPAFII	viability after 35 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	0.6387016950757317	[458]	[389,329,NaN]	4	hSpCas9	negative selection	9987958
73293571	73293594	2	+	27869803	HPAFII	viability after 35 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.6892730007711148	[193]	[179,133,NaN]	4	hSpCas9	negative selection	9987959
73292104	73292127	2	-	27869803	HPAFII	viability after 31 days	GGCCTATGACGCTTTCCCGCTGG	EGR4	ENSG00000135625	-0.2829064358556763	[87]	[64,13,NaN]	-2	hSpCas9	negative selection	10070403
73292441	73292464	2	+	27869803	HPAFII	viability after 31 days	CCAGAACGCCTCTGGGAAAGGGG	EGR4	ENSG00000135625	0.06327912442545425	[632]	[497,232,NaN]	0	hSpCas9	negative selection	10070404
73292668	73292691	2	+	27869803	HPAFII	viability after 31 days	CGCTGTAGCTGAGGCCGGGAGGG	EGR4	ENSG00000135625	0.5795448903745084	[306]	[267,245,NaN]	4	hSpCas9	negative selection	10070405
73293177	73293200	2	+	27869803	HPAFII	viability after 31 days	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-0.06771377425205527	[61]	[59,3,NaN]	0	hSpCas9	negative selection	10070406
73293525	73293548	2	-	27869803	HPAFII	viability after 31 days	AGCCCGGCAGCGCTTTGGAGAGG	EGR4	ENSG00000135625	0.6738649946600422	[458]	[409,411,NaN]	5	hSpCas9	negative selection	10070407
73293571	73293594	2	+	27869803	HPAFII	viability after 31 days	TTATATAGCTGCGGCGGCGCTGG	EGR4	ENSG00000135625	0.9930137006944413	[193]	[209,223,NaN]	7	hSpCas9	negative selection	10070408
73293617	73293640	2	-	28162770	P31FUJ	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.2878754699389152	[282]	[405]	3	hSpCas9	negative selection	10148634
73293565	73293588	2	-	28162770	P31FUJ	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	0.6493348432911776	[579]	[1068]	7	hSpCas9	negative selection	10148635
73293460	73293483	2	+	28162770	P31FUJ	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	0.9101557494276644	[23]	[52]	9	hSpCas9	negative selection	10148636
73293406	73293429	2	-	28162770	P31FUJ	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	0.29298236037200404	[140]	[202]	3	hSpCas9	negative selection	10148637
73293267	73293290	2	+	28162770	P31FUJ	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	-0.36311022676010973	[219]	[200]	-3	hSpCas9	negative selection	10148638
73293222	73293245	2	+	28162770	P31FUJ	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.32492040640280995	[96]	[90]	-3	hSpCas9	negative selection	10148639
73293177	73293200	2	+	28162770	P31FUJ	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-2.3068027858581557	[79]	[18]	-8	hSpCas9	negative selection	10148640
73293520	73293543	2	-	28162770	P31FUJ	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-0.5012910403402802	[52]	[43]	-4	hSpCas9	negative selection	10148641
73293428	73293451	2	-	28162770	P31FUJ	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	-0.13455811111167088	[297]	[318]	-1	hSpCas9	negative selection	10148642
73293290	73293313	2	+	28162770	P31FUJ	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	0.8681754433104423	[199]	[428]	8	hSpCas9	negative selection	10148643
73293617	73293640	2	-	28162770	TF1	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10318000
73293565	73293588	2	-	28162770	TF1	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	NaN	[NaN]	[441]	1	hSpCas9	negative selection	10318001
73293460	73293483	2	+	28162770	TF1	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10318002
73293406	73293429	2	-	28162770	TF1	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	NaN	[NaN]	[160]	1	hSpCas9	negative selection	10318003
73293267	73293290	2	+	28162770	TF1	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10318004
73293222	73293245	2	+	28162770	TF1	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10318005
73293177	73293200	2	+	28162770	TF1	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10318006
73293520	73293543	2	-	28162770	TF1	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10318007
73293428	73293451	2	-	28162770	TF1	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	NaN	[NaN]	[176]	1	hSpCas9	negative selection	10318008
73293290	73293313	2	+	28162770	TF1	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	NaN	[NaN]	[78]	1	hSpCas9	negative selection	10318009
73293617	73293640	2	-	28162770	SKM1	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.8667966136836904	[66]	[215]	7	hSpCas9	negative selection	10487366
73293565	73293588	2	-	28162770	SKM1	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	0.047528370082585925	[132]	[242]	0	hSpCas9	negative selection	10487367
73293460	73293483	2	+	28162770	SKM1	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	0.9853532240355989	[11]	[41]	8	hSpCas9	negative selection	10487368
73293406	73293429	2	-	28162770	SKM1	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	1.0817829867186912	[30]	[115]	8	hSpCas9	negative selection	10487369
73293267	73293290	2	+	28162770	SKM1	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	0.4946706714138617	[54]	[136]	5	hSpCas9	negative selection	10487370
73293222	73293245	2	+	28162770	SKM1	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.5875364443849824	[16]	[19]	-5	hSpCas9	negative selection	10487371
73293177	73293200	2	+	28162770	SKM1	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-0.37454272105078434	[10]	[14]	-3	hSpCas9	negative selection	10487372
73293520	73293543	2	-	28162770	SKM1	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-0.8220016980220055	[14]	[14]	-6	hSpCas9	negative selection	10487373
73293428	73293451	2	-	28162770	SKM1	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	0.5545616534422028	[56]	[147]	5	hSpCas9	negative selection	10487374
73293290	73293313	2	+	28162770	SKM1	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.08503610385579938	[50]	[84]	0	hSpCas9	negative selection	10487375
73293617	73293640	2	-	28162770	SKM1	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.8667966136836904	[66]	[215]	7	hSpCas9	negative selection	10656732
73293565	73293588	2	-	28162770	SKM1	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	0.047528370082585925	[132]	[242]	0	hSpCas9	negative selection	10656733
73293460	73293483	2	+	28162770	SKM1	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	0.9853532240355989	[11]	[41]	8	hSpCas9	negative selection	10656734
73293406	73293429	2	-	28162770	SKM1	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	1.0817829867186912	[30]	[115]	8	hSpCas9	negative selection	10656735
73293267	73293290	2	+	28162770	SKM1	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	0.4946706714138617	[54]	[136]	5	hSpCas9	negative selection	10656736
73293222	73293245	2	+	28162770	SKM1	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.5875364443849824	[16]	[19]	-5	hSpCas9	negative selection	10656737
73293177	73293200	2	+	28162770	SKM1	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-0.37454272105078434	[10]	[14]	-3	hSpCas9	negative selection	10656738
73293520	73293543	2	-	28162770	SKM1	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-0.8220016980220055	[14]	[14]	-6	hSpCas9	negative selection	10656739
73293428	73293451	2	-	28162770	SKM1	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	0.5545616534422028	[56]	[147]	5	hSpCas9	negative selection	10656740
73293290	73293313	2	+	28162770	SKM1	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.08503610385579938	[50]	[84]	0	hSpCas9	negative selection	10656741
73293617	73293640	2	-	28162770	PL21	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.9915529926779028	[259]	[224]	8	hSpCas9	negative selection	10826098
73293565	73293588	2	-	28162770	PL21	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	0.21550392414149933	[466]	[235]	2	hSpCas9	negative selection	10826099
73293460	73293483	2	+	28162770	PL21	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	0.20013961448931994	[35]	[17]	1	hSpCas9	negative selection	10826100
73293406	73293429	2	-	28162770	PL21	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	-1.0699495488784243	[163]	[33]	-6	hSpCas9	negative selection	10826101
73293267	73293290	2	+	28162770	PL21	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	-0.09076158477741772	[229]	[93]	0	hSpCas9	negative selection	10826102
73293222	73293245	2	+	28162770	PL21	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.4392706702542124	[80]	[25]	-3	hSpCas9	negative selection	10826103
73293177	73293200	2	+	28162770	PL21	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.13959807255426937	[72]	[34]	1	hSpCas9	negative selection	10826104
73293520	73293543	2	-	28162770	PL21	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-4.323422341567693	[45]	[0]	-9	hSpCas9	negative selection	10826105
73293428	73293451	2	-	28162770	PL21	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	-0.3417541643399502	[197]	[67]	-2	hSpCas9	negative selection	10826106
73293290	73293313	2	+	28162770	PL21	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.5490522820101453	[157]	[46]	-4	hSpCas9	negative selection	10826107
73293617	73293640	2	-	28162770	P31FUJ	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.2878754699389152	[282]	[405]	3	hSpCas9	negative selection	10995464
73293565	73293588	2	-	28162770	P31FUJ	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	0.6493348432911776	[579]	[1068]	7	hSpCas9	negative selection	10995465
73293460	73293483	2	+	28162770	P31FUJ	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	0.9101557494276644	[23]	[52]	9	hSpCas9	negative selection	10995466
73293406	73293429	2	-	28162770	P31FUJ	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	0.29298236037200404	[140]	[202]	3	hSpCas9	negative selection	10995467
73293267	73293290	2	+	28162770	P31FUJ	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	-0.36311022676010973	[219]	[200]	-3	hSpCas9	negative selection	10995468
73293222	73293245	2	+	28162770	P31FUJ	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.32492040640280995	[96]	[90]	-3	hSpCas9	negative selection	10995469
73293177	73293200	2	+	28162770	P31FUJ	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-2.3068027858581557	[79]	[18]	-8	hSpCas9	negative selection	10995470
73293520	73293543	2	-	28162770	P31FUJ	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-0.5012910403402802	[52]	[43]	-4	hSpCas9	negative selection	10995471
73293428	73293451	2	-	28162770	P31FUJ	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	-0.13455811111167088	[297]	[318]	-1	hSpCas9	negative selection	10995472
73293290	73293313	2	+	28162770	P31FUJ	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	0.8681754433104423	[199]	[428]	8	hSpCas9	negative selection	10995473
73293617	73293640	2	-	28162770	OCIAML5	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	-0.0751922552611547	[163]	[280]	0	hSpCas9	negative selection	11164830
73293565	73293588	2	-	28162770	OCIAML5	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	-0.4776710560824988	[296]	[384]	-3	hSpCas9	negative selection	11164831
73293460	73293483	2	+	28162770	OCIAML5	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	-0.8520665708639967	[12]	[12]	-5	hSpCas9	negative selection	11164832
73293406	73293429	2	-	28162770	OCIAML5	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	1.5685091119562768	[64]	[347]	9	hSpCas9	negative selection	11164833
73293267	73293290	2	+	28162770	OCIAML5	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	1.09670810578083	[85]	[331]	8	hSpCas9	negative selection	11164834
73293222	73293245	2	+	28162770	OCIAML5	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.14793342913600305	[40]	[81]	1	hSpCas9	negative selection	11164835
73293177	73293200	2	+	28162770	OCIAML5	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-0.9775974529478558	[59]	[54]	-6	hSpCas9	negative selection	11164836
73293520	73293543	2	-	28162770	OCIAML5	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-0.009607847850476858	[28]	[51]	0	hSpCas9	negative selection	11164837
73293428	73293451	2	-	28162770	OCIAML5	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	0.3966125419927268	[100]	[239]	3	hSpCas9	negative selection	11164838
73293290	73293313	2	+	28162770	OCIAML5	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-0.09352389815933651	[145]	[246]	0	hSpCas9	negative selection	11164839
73293617	73293640	2	-	28162770	EOL1	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	-0.09651384395729512	[482]	[237]	0	hSpCas9	negative selection	11334196
73293565	73293588	2	-	28162770	EOL1	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	0.03224196850861294	[528]	[284]	0	hSpCas9	negative selection	11334197
73293460	73293483	2	+	28162770	EOL1	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	0.6330849574102233	[81]	[66]	5	hSpCas9	negative selection	11334198
73293406	73293429	2	-	28162770	EOL1	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	0.9384869625284082	[205]	[207]	7	hSpCas9	negative selection	11334199
73293267	73293290	2	+	28162770	EOL1	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	0.3304019486840429	[393]	[260]	3	hSpCas9	negative selection	11334200
73293222	73293245	2	+	28162770	EOL1	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-1.0615130374715918	[102]	[25]	-6	hSpCas9	negative selection	11334201
73293177	73293200	2	+	28162770	EOL1	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-0.14154141888723792	[66]	[31]	-1	hSpCas9	negative selection	11334202
73293520	73293543	2	-	28162770	EOL1	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	1.661513365736741	[38]	[64]	9	hSpCas9	negative selection	11334203
73293428	73293451	2	-	28162770	EOL1	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	0.704047409575295	[253]	[217]	6	hSpCas9	negative selection	11334204
73293290	73293313	2	+	28162770	EOL1	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	1.5095102722916907	[221]	[332]	9	hSpCas9	negative selection	11334205
73293617	73293640	2	-	28162770	MOLM13	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	-0.12811139062902543	[327]	[216]	-1	hSpCas9	negative selection	11503562
73293565	73293588	2	-	28162770	MOLM13	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	-0.022060004316357018	[638]	[454]	0	hSpCas9	negative selection	11503563
73293460	73293483	2	+	28162770	MOLM13	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	1.5674250550954931	[55]	[119]	9	hSpCas9	negative selection	11503564
73293406	73293429	2	-	28162770	MOLM13	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	0.5149379543490102	[180]	[186]	4	hSpCas9	negative selection	11503565
73293267	73293290	2	+	28162770	MOLM13	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	0.13007138472763052	[387]	[306]	0	hSpCas9	negative selection	11503566
73293222	73293245	2	+	28162770	MOLM13	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	1.1922549389311514	[114]	[189]	8	hSpCas9	negative selection	11503567
73293177	73293200	2	+	28162770	MOLM13	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.3790801145867231	[66]	[62]	2	hSpCas9	negative selection	11503568
73293520	73293543	2	-	28162770	MOLM13	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-0.610113130456694	[56]	[26]	-4	hSpCas9	negative selection	11503569
73293428	73293451	2	-	28162770	MOLM13	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	0.05285188226573481	[283]	[212]	0	hSpCas9	negative selection	11503570
73293290	73293313	2	+	28162770	MOLM13	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-1.5683308063681747	[241]	[58]	-6	hSpCas9	negative selection	11503571
73293617	73293640	2	-	28162770	HEL	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.0027349677212388235	[373]	[239]	0	hSpCas9	negative selection	11672928
73293565	73293588	2	-	28162770	HEL	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	-0.15101278825742648	[474]	[273]	-1	hSpCas9	negative selection	11672929
73293460	73293483	2	+	28162770	HEL	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	-0.435263680000916	[37]	[17]	-3	hSpCas9	negative selection	11672930
73293406	73293429	2	-	28162770	HEL	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	1.3299513909694636	[117]	[189]	9	hSpCas9	negative selection	11672931
73293267	73293290	2	+	28162770	HEL	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	-0.196540857453484	[296]	[165]	-1	hSpCas9	negative selection	11672932
73293222	73293245	2	+	28162770	HEL	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.8915975956508311	[83]	[28]	-5	hSpCas9	negative selection	11672933
73293177	73293200	2	+	28162770	HEL	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-1.579653589336091	[55]	[11]	-7	hSpCas9	negative selection	11672934
73293520	73293543	2	-	28162770	HEL	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-0.08717200463189867	[67]	[40]	0	hSpCas9	negative selection	11672935
73293428	73293451	2	-	28162770	HEL	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	-0.4804093987725078	[219]	[100]	-3	hSpCas9	negative selection	11672936
73293290	73293313	2	+	28162770	HEL	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	0.8803176571514808	[161]	[190]	7	hSpCas9	negative selection	11672937
73293617	73293640	2	-	28162770	MV411	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.11564767822723399	[251]	[229]	1	hSpCas9	negative selection	11842294
73293565	73293588	2	-	28162770	MV411	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	0.39481131855677143	[436]	[483]	3	hSpCas9	negative selection	11842295
73293460	73293483	2	+	28162770	MV411	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	-2.100485752637532	[55]	[10]	-8	hSpCas9	negative selection	11842296
73293406	73293429	2	-	28162770	MV411	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	1.0184120371138805	[108]	[185]	8	hSpCas9	negative selection	11842297
73293267	73293290	2	+	28162770	MV411	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	0.5759382995936237	[218]	[274]	5	hSpCas9	negative selection	11842298
73293222	73293245	2	+	28162770	MV411	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	0.1813483603250028	[66]	[63]	1	hSpCas9	negative selection	11842299
73293177	73293200	2	+	28162770	MV411	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.3145517466413126	[41]	[43]	2	hSpCas9	negative selection	11842300
73293520	73293543	2	-	28162770	MV411	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-0.1151325286019329	[26]	[20]	-1	hSpCas9	negative selection	11842301
73293428	73293451	2	-	28162770	MV411	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	-0.5952504443871096	[216]	[120]	-4	hSpCas9	negative selection	11842302
73293290	73293313	2	+	28162770	MV411	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-1.569698392067414	[147]	[41]	-7	hSpCas9	negative selection	11842303
73293617	73293640	2	-	28162770	MONOMAC1	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.6917456743418965	[154]	[286]	6	hSpCas9	negative selection	12011660
73293565	73293588	2	-	28162770	MONOMAC1	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	-0.27977727806748987	[304]	[287]	-2	hSpCas9	negative selection	12011661
73293460	73293483	2	+	28162770	MONOMAC1	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	-0.43407604436040326	[32]	[27]	-4	hSpCas9	negative selection	12011662
73293406	73293429	2	-	28162770	MONOMAC1	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	0.3531602355009259	[83]	[122]	3	hSpCas9	negative selection	12011663
73293267	73293290	2	+	28162770	MONOMAC1	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	0.5456880163953375	[149]	[250]	5	hSpCas9	negative selection	12011664
73293222	73293245	2	+	28162770	MONOMAC1	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.39867070822920403	[45]	[39]	-3	hSpCas9	negative selection	12011665
73293177	73293200	2	+	28162770	MONOMAC1	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-1.1095740058092145	[31]	[16]	-7	hSpCas9	negative selection	12011666
73293520	73293543	2	-	28162770	MONOMAC1	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	0.3334778696392262	[17]	[25]	3	hSpCas9	negative selection	12011667
73293428	73293451	2	-	28162770	MONOMAC1	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	0.30672957081362173	[133]	[189]	3	hSpCas9	negative selection	12011668
73293290	73293313	2	+	28162770	MONOMAC1	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	-1.2267841904536056	[97]	[47]	-7	hSpCas9	negative selection	12011669
73293617	73293640	2	-	28162770	OCIAML2	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.11854492676590944	[56]	[342]	1	hSpCas9	negative selection	12181026
73293565	73293588	2	-	28162770	OCIAML2	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	-0.2267042423560719	[94]	[449]	-2	hSpCas9	negative selection	12181027
73293460	73293483	2	+	28162770	OCIAML2	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	-0.28620525410473396	[10]	[49]	-2	hSpCas9	negative selection	12181028
73293406	73293429	2	-	28162770	OCIAML2	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	1.2062551649200342	[18]	[242]	9	hSpCas9	negative selection	12181029
73293267	73293290	2	+	28162770	OCIAML2	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	-0.5446304066859381	[49]	[189]	-4	hSpCas9	negative selection	12181030
73293222	73293245	2	+	28162770	OCIAML2	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	1.6274022577183653	[7]	[136]	9	hSpCas9	negative selection	12181031
73293177	73293200	2	+	28162770	OCIAML2	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	-1.3237884369128903	[13]	[30]	-7	hSpCas9	negative selection	12181032
73293520	73293543	2	-	28162770	OCIAML2	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-1.3007048237998489	[7]	[17]	-7	hSpCas9	negative selection	12181033
73293428	73293451	2	-	28162770	OCIAML2	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	-0.5993631393643641	[40]	[149]	-4	hSpCas9	negative selection	12181034
73293290	73293313	2	+	28162770	OCIAML2	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	0.031870515287021894	[23]	[135]	0	hSpCas9	negative selection	12181035
73293617	73293640	2	-	28162770	OCIAML3	viability	GGGGCCTCCCAAAATGGCAGTGG	EGR4	ENSG00000135625	0.04540264441936959	[77]	[242]	0	hSpCas9	negative selection	12350392
73293565	73293588	2	-	28162770	OCIAML3	viability	CCGCCGCAGCTATATAAGTGGGG	EGR4	ENSG00000135625	0.6250021416176326	[121]	[567]	6	hSpCas9	negative selection	12350393
73293460	73293483	2	+	28162770	OCIAML3	viability	GGAAAGGAGTCGGGGAGCCGCGG	EGR4	ENSG00000135625	-2.5008982359326817	[14]	[7]	-9	hSpCas9	negative selection	12350394
73293406	73293429	2	-	28162770	OCIAML3	viability	GCGCCTAGGTCTGTGCGCTGCGG	EGR4	ENSG00000135625	-0.23645563570607953	[31]	[81]	-2	hSpCas9	negative selection	12350395
73293267	73293290	2	+	28162770	OCIAML3	viability	GGACTTGACGAGGAGCGCGTCGG	EGR4	ENSG00000135625	0.03826057517534984	[59]	[185]	0	hSpCas9	negative selection	12350396
73293222	73293245	2	+	28162770	OCIAML3	viability	CAGCCGGGGCAATTCAGCGCTGG	EGR4	ENSG00000135625	-0.09924294857458538	[10]	[30]	-1	hSpCas9	negative selection	12350397
73293177	73293200	2	+	28162770	OCIAML3	viability	CTTACCTCCAGGGTAGCCGGTGG	EGR4	ENSG00000135625	0.4701226970955523	[10]	[45]	4	hSpCas9	negative selection	12350398
73293520	73293543	2	-	28162770	OCIAML3	viability	GGCAGCGCTTTGGAGAGGCGAGG	EGR4	ENSG00000135625	-2.2220388629372048	[16]	[10]	-8	hSpCas9	negative selection	12350399
73293428	73293451	2	-	28162770	OCIAML3	viability	GTGCCCGAAGCCAGGAGCCCGGG	EGR4	ENSG00000135625	0.43513870533535326	[48]	[199]	4	hSpCas9	negative selection	12350400
73293290	73293313	2	+	28162770	OCIAML3	viability	GTTCGGAAAACTCGCTAAGGTGG	EGR4	ENSG00000135625	0.4192891822892947	[53]	[217]	4	hSpCas9	negative selection	12350401