Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 11082
• Symbol: ESM1
• Description: endothelial cell specific molecule 1

DataSource: http://genomecrispr.dkfz.de/#!/results/ESM1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
54985439	54985462	5	-	26472758	Jiyoye	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.1683885219187568	[117]	[99]	1	hSpCas9	negative selection	51826
54985459	54985482	5	+	26472758	Jiyoye	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	-0.3009353499881477	[164]	[100]	-2	hSpCas9	negative selection	51827
54985285	54985308	5	-	26472758	Jiyoye	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.293518599710306	[131]	[121]	2	hSpCas9	negative selection	51828
54985335	54985358	5	-	26472758	Jiyoye	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	0.7571178525628323	[50]	[64]	5	hSpCas9	negative selection	51829
54985261	54985284	5	+	26472758	Jiyoye	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	0.4742895773644104	[83]	[87]	3	hSpCas9	negative selection	51830
54985216	54985239	5	-	26472758	Jiyoye	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	0.7277972788926108	[220]	[275]	5	hSpCas9	negative selection	51831
54985473	54985496	5	+	26472758	Jiyoye	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	0.6807404548318366	[90]	[109]	5	hSpCas9	negative selection	51832
54985383	54985406	5	-	26472758	Jiyoye	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	0.7450450202622573	[71]	[90]	5	hSpCas9	negative selection	51833
54985376	54985399	5	+	26472758	Jiyoye	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	-0.1256986080668283	[67]	[46]	-1	hSpCas9	negative selection	51834
54985301	54985324	5	-	26472758	Jiyoye	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.18671040874054	[373]	[320]	1	hSpCas9	negative selection	51835
54985439	54985462	5	-	26472758	KBM7	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.652598053574056	[388,210]	[355,90]	7	hSpCas9	negative selection	242944
54985459	54985482	5	+	26472758	KBM7	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	0.4353735730771371	[467,565]	[408,265]	5	hSpCas9	negative selection	242945
54985285	54985308	5	-	26472758	KBM7	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	-0.17273541207340098	[815,636]	[362,244]	-2	hSpCas9	negative selection	242946
54985335	54985358	5	-	26472758	KBM7	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	0.3839425739590517	[250,283]	[128,198]	4	hSpCas9	negative selection	242947
54985261	54985284	5	+	26472758	KBM7	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	0.06047448275996781	[324,199]	[112,137]	0	hSpCas9	negative selection	242948
54985216	54985239	5	-	26472758	KBM7	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	-0.41581340207741646	[1583,1041]	[459,450]	-4	hSpCas9	negative selection	242949
54985473	54985496	5	+	26472758	KBM7	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	-0.3369892435306915	[632,681]	[135,345]	-3	hSpCas9	negative selection	242950
54985383	54985406	5	-	26472758	KBM7	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	1.4392110922050194	[191,243]	[278,285]	9	hSpCas9	negative selection	242951
54985376	54985399	5	+	26472758	KBM7	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	1.3723091678955086	[277,202]	[364,221]	9	hSpCas9	negative selection	242952
54985301	54985324	5	-	26472758	KBM7	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.4088524873473125	[1496,1329]	[780,970]	4	hSpCas9	negative selection	242953
54985439	54985462	5	-	26472758	Raji	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.33318905601238186	[189]	[34]	-3	hSpCas9	negative selection	434062
54985459	54985482	5	+	26472758	Raji	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	-0.02726599132118218	[302]	[68]	0	hSpCas9	negative selection	434063
54985285	54985308	5	-	26472758	Raji	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.8434027896955166	[304]	[126]	7	hSpCas9	negative selection	434064
54985335	54985358	5	-	26472758	Raji	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	1.172971877001176	[85]	[44]	8	hSpCas9	negative selection	434065
54985261	54985284	5	+	26472758	Raji	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	0.4839468868378076	[113]	[36]	4	hSpCas9	negative selection	434066
54985216	54985239	5	-	26472758	Raji	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	-0.17881685503923705	[677]	[138]	-1	hSpCas9	negative selection	434067
54985473	54985496	5	+	26472758	Raji	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	-0.07606260572233159	[267]	[58]	0	hSpCas9	negative selection	434068
54985383	54985406	5	-	26472758	Raji	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	0.23917340792914077	[229]	[62]	2	hSpCas9	negative selection	434069
54985376	54985399	5	+	26472758	Raji	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.9399267895220368	[145]	[64]	8	hSpCas9	negative selection	434070
54985301	54985324	5	-	26472758	Raji	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.5327778274496189	[693]	[232]	5	hSpCas9	negative selection	434071
54985439	54985462	5	-	26472758	K562	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.28282827519842213	[293]	[203]	-2	hSpCas9	negative selection	625180
54985459	54985482	5	+	26472758	K562	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	0.3793055124144362	[601]	[660]	3	hSpCas9	negative selection	625181
54985285	54985308	5	-	26472758	K562	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.14423985524581096	[640]	[597]	1	hSpCas9	negative selection	625182
54985335	54985358	5	-	26472758	K562	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	-1.4327601442756834	[322]	[100]	-6	hSpCas9	negative selection	625183
54985261	54985284	5	+	26472758	K562	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	-0.8694011718907153	[144]	[66]	-5	hSpCas9	negative selection	625184
54985216	54985239	5	-	26472758	K562	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	-0.02214736913760018	[1226]	[1019]	0	hSpCas9	negative selection	625185
54985473	54985496	5	+	26472758	K562	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	1.3904969871543915	[365]	[809]	9	hSpCas9	negative selection	625186
54985383	54985406	5	-	26472758	K562	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	0.6604126042033096	[376]	[502]	5	hSpCas9	negative selection	625187
54985376	54985399	5	+	26472758	K562	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	-0.2062426813431183	[245]	[179]	-1	hSpCas9	negative selection	625188
54985301	54985324	5	-	26472758	K562	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	-0.035256880168843985	[1429]	[1177]	0	hSpCas9	negative selection	625189
54979318	54979341	5	+	26627737	DLD1	viability	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	-0.607553730058538	[1399]	[285,452,150]	-5	hSpCas9	negative selection	829003
54979350	54979373	5	+	26627737	DLD1	viability	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	1.6776585309281176	[0]	[0,0,0]	9	hSpCas9	negative selection	829004
54985376	54985399	5	+	26627737	DLD1	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	-0.504737865455748	[1117]	[207,165,345]	-5	hSpCas9	negative selection	829005
54985439	54985462	5	-	26627737	DLD1	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.35539151198634555	[962]	[509,297,348]	3	hSpCas9	negative selection	829006
54985443	54985466	5	+	26627737	DLD1	viability	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	0.12565274051535769	[792]	[309,359,161]	1	hSpCas9	negative selection	829007
54979318	54979341	5	+	26627737	GBM cells	viability after 5 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.8157726395854397	[374]	[340,366]	9	hSpCas9	negative selection	911318
54979350	54979373	5	+	26627737	GBM cells	viability after 5 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	0.8989138748856851	[0]	[0,0]	9	hSpCas9	negative selection	911319
54985376	54985399	5	+	26627737	GBM cells	viability after 5 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.3730864982518618	[238]	[184,146]	6	hSpCas9	negative selection	911320
54985439	54985462	5	-	26627737	GBM cells	viability after 5 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.6932084174083366	[706]	[200,267]	-8	hSpCas9	negative selection	911321
54985443	54985466	5	+	26627737	GBM cells	viability after 5 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	-0.007560298424981626	[432]	[199,261]	0	hSpCas9	negative selection	911322
54979318	54979341	5	+	26627737	GBM cells	viability after 13 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.6137975060030763	[374]	[269,344]	7	hSpCas9	negative selection	993633
54979350	54979373	5	+	26627737	GBM cells	viability after 13 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	0.8821031235784469	[0]	[0,0]	9	hSpCas9	negative selection	993634
54985376	54985399	5	+	26627737	GBM cells	viability after 13 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.36035981206660395	[238]	[214,126]	4	hSpCas9	negative selection	993635
54985439	54985462	5	-	26627737	GBM cells	viability after 13 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.9351585752146537	[706]	[268,144]	-8	hSpCas9	negative selection	993636
54985443	54985466	5	+	26627737	GBM cells	viability after 13 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	0.358028129235086	[432]	[390,227]	4	hSpCas9	negative selection	993637
54979318	54979341	5	+	26627737	GBM cells	viability after 21 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.9912646120044022	[374]	[451,361]	8	hSpCas9	negative selection	1075948
54979350	54979373	5	+	26627737	GBM cells	viability after 21 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	0.8802332996156581	[0]	[0,0]	8	hSpCas9	negative selection	1075949
54985376	54985399	5	+	26627737	GBM cells	viability after 21 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.10945078326911523	[238]	[149,130]	1	hSpCas9	negative selection	1075950
54985439	54985462	5	-	26627737	GBM cells	viability after 21 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-1.0941926268291047	[706]	[181,177]	-7	hSpCas9	negative selection	1075951
54985443	54985466	5	+	26627737	GBM cells	viability after 21 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	0.5492065122361898	[432]	[338,348]	5	hSpCas9	negative selection	1075952
54979318	54979341	5	+	26627737	RPE1	viability after 9 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.0002745157079767635	[1343]	[436,399]	0	hSpCas9	negative selection	1158263
54979350	54979373	5	+	26627737	RPE1	viability after 9 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	1.6754465303148196	[0]	[0,0]	8	hSpCas9	negative selection	1158264
54985376	54985399	5	+	26627737	RPE1	viability after 9 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	1.0102559503861743	[1065]	[659,687]	6	hSpCas9	negative selection	1158265
54985439	54985462	5	-	26627737	RPE1	viability after 9 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.0710650942332296	[1353]	[413,389]	0	hSpCas9	negative selection	1158266
54985443	54985466	5	+	26627737	RPE1	viability after 9 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	1.5643859435592482	[471]	[543,298]	8	hSpCas9	negative selection	1158267
54979318	54979341	5	+	26627737	RPE1	viability after 12 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	-0.52089027448622	[1343]	[290,209]	-4	hSpCas9	negative selection	1240578
54979350	54979373	5	+	26627737	RPE1	viability after 12 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	1.8961114116731377	[0]	[0,0]	8	hSpCas9	negative selection	1240579
54985376	54985399	5	+	26627737	RPE1	viability after 12 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	1.1021600881229356	[1065]	[608,620]	6	hSpCas9	negative selection	1240580
54985439	54985462	5	-	26627737	RPE1	viability after 12 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.4537633346511154	[1353]	[539,453]	3	hSpCas9	negative selection	1240581
54985443	54985466	5	+	26627737	RPE1	viability after 12 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	2.158199429909903	[471]	[549,582]	9	hSpCas9	negative selection	1240582
54979318	54979341	5	+	26627737	RPE1	viability after 15 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.37664193811944613	[1343]	[543,444]	2	hSpCas9	negative selection	1322893
54979350	54979373	5	+	26627737	RPE1	viability after 15 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	1.8217488738718943	[0]	[0,0]	8	hSpCas9	negative selection	1322894
54985376	54985399	5	+	26627737	RPE1	viability after 15 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	1.572182681055865	[1065]	[1027,769]	8	hSpCas9	negative selection	1322895
54985439	54985462	5	-	26627737	RPE1	viability after 15 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.2963159471301693	[1353]	[478,461]	2	hSpCas9	negative selection	1322896
54985443	54985466	5	+	26627737	RPE1	viability after 15 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	1.9625528698071713	[471]	[610,432]	8	hSpCas9	negative selection	1322897
54979318	54979341	5	+	26627737	RPE1	viability after 18 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.5158740594690008	[1343]	[725,296]	3	hSpCas9	negative selection	1405208
54979350	54979373	5	+	26627737	RPE1	viability after 18 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	1.889668260100743	[0]	[0,0]	8	hSpCas9	negative selection	1405209
54985376	54985399	5	+	26627737	RPE1	viability after 18 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	1.1747201285713562	[1065]	[632,666]	6	hSpCas9	negative selection	1405210
54985439	54985462	5	-	26627737	RPE1	viability after 18 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.07920183865636765	[1353]	[342,431]	0	hSpCas9	negative selection	1405211
54985443	54985466	5	+	26627737	RPE1	viability after 18 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	2.2544015770684336	[471]	[702,505]	9	hSpCas9	negative selection	1405212
54979318	54979341	5	+	26627737	HeLa	viability after 8 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.1500119836992928	[702]	[630,238,220]	1	hSpCas9	negative selection	1487523
54979350	54979373	5	+	26627737	HeLa	viability after 8 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	1.200473099817617	[0]	[0,0,0]	8	hSpCas9	negative selection	1487524
54985376	54985399	5	+	26627737	HeLa	viability after 8 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.14737036354555466	[626]	[332,332,250]	1	hSpCas9	negative selection	1487525
54985439	54985462	5	-	26627737	HeLa	viability after 8 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-1.4685235751122716	[1807]	[306,253,295]	-9	hSpCas9	negative selection	1487526
54985443	54985466	5	+	26627737	HeLa	viability after 8 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	0.35216659372797354	[531]	[610,183,169]	3	hSpCas9	negative selection	1487527
54979318	54979341	5	+	26627737	HeLa	viability after 12 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.15312742428365933	[702]	[535,250,195]	1	hSpCas9	negative selection	1569838
54979350	54979373	5	+	26627737	HeLa	viability after 12 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	1.2748581272013126	[0]	[0,0,0]	8	hSpCas9	negative selection	1569839
54985376	54985399	5	+	26627737	HeLa	viability after 12 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.22523582982819657	[626]	[177,312,412]	2	hSpCas9	negative selection	1569840
54985439	54985462	5	-	26627737	HeLa	viability after 12 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.7436228430876126	[1807]	[451,350,545]	-6	hSpCas9	negative selection	1569841
54985443	54985466	5	+	26627737	HeLa	viability after 12 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	0.4975272749472138	[531]	[264,242,428]	4	hSpCas9	negative selection	1569842
54979318	54979341	5	+	26627737	HeLa	viability after 15 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	-0.1739593770936414	[702]	[373,161,220]	-1	hSpCas9	negative selection	1652153
54979350	54979373	5	+	26627737	HeLa	viability after 15 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	1.2965331123080048	[0]	[0,0,0]	8	hSpCas9	negative selection	1652154
54985376	54985399	5	+	26627737	HeLa	viability after 15 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.40966229265833853	[626]	[200,333,495]	3	hSpCas9	negative selection	1652155
54985439	54985462	5	-	26627737	HeLa	viability after 15 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.9256283557801972	[1807]	[463,339,354]	-7	hSpCas9	negative selection	1652156
54985443	54985466	5	+	26627737	HeLa	viability after 15 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	1.1339653728898154	[531]	[433,425,573]	7	hSpCas9	negative selection	1652157
54979318	54979341	5	+	26627737	HeLa	viability after 18 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	-0.22107225210096482	[702]	[235,132,220]	-2	hSpCas9	negative selection	1734468
54979350	54979373	5	+	26627737	HeLa	viability after 18 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	1.6067387639618715	[0]	[0,0,0]	9	hSpCas9	negative selection	1734469
54985376	54985399	5	+	26627737	HeLa	viability after 18 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.40678754240550596	[626]	[133,275,495]	3	hSpCas9	negative selection	1734470
54985439	54985462	5	-	26627737	HeLa	viability after 18 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.9374520099989399	[1807]	[303,282,354]	-7	hSpCas9	negative selection	1734471
54985443	54985466	5	+	26627737	HeLa	viability after 18 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	1.1021092769684893	[531]	[273,348,573]	7	hSpCas9	negative selection	1734472
54979318	54979341	5	+	26627737	HCT116	viability after 6 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	1.351555136254864	[830]	[217,396]	7	hSpCas9	negative selection	1816783
54979350	54979373	5	+	26627737	HCT116	viability after 6 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	2.6692602571875668	[0]	[0,0]	9	hSpCas9	negative selection	1816784
54985376	54985399	5	+	26627737	HCT116	viability after 6 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	1.2083737440638298	[776]	[590,111]	6	hSpCas9	negative selection	1816785
54985439	54985462	5	-	26627737	HCT116	viability after 6 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.16777212199778568	[1946]	[843,67]	0	hSpCas9	negative selection	1816786
54985443	54985466	5	+	26627737	HCT116	viability after 6 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	-0.14264328588697006	[1083]	[203,126]	-1	hSpCas9	negative selection	1816787
54979318	54979341	5	+	26627737	HCT116	viability after 8 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	-0.28107930687951466	[678]	[327,279,315]	-3	hSpCas9	negative selection	1899098
54979350	54979373	5	+	26627737	HCT116	viability after 8 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	0.8598070938499998	[0]	[0,0,0]	7	hSpCas9	negative selection	1899099
54985376	54985399	5	+	26627737	HCT116	viability after 8 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.6918872454797597	[359]	[344,314,301]	6	hSpCas9	negative selection	1899100
54985439	54985462	5	-	26627737	HCT116	viability after 8 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.1543943685757143	[778]	[518,441,472]	1	hSpCas9	negative selection	1899101
54985443	54985466	5	+	26627737	HCT116	viability after 8 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	-0.3516900271008919	[707]	[267,382,265]	-4	hSpCas9	negative selection	1899102
54979318	54979341	5	+	26627737	HCT116	viability after 9 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	1.6293158553655864	[830]	[848,557]	8	hSpCas9	negative selection	1981413
54979350	54979373	5	+	26627737	HCT116	viability after 9 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	1.9049898113534676	[0]	[0,0]	9	hSpCas9	negative selection	1981414
54985376	54985399	5	+	26627737	HCT116	viability after 9 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.96226672015936	[776]	[339,454]	6	hSpCas9	negative selection	1981415
54985439	54985462	5	-	26627737	HCT116	viability after 9 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-1.1120732119285008	[1946]	[268,217]	-7	hSpCas9	negative selection	1981416
54985443	54985466	5	+	26627737	HCT116	viability after 9 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	0.5237490629737696	[1083]	[576,288]	4	hSpCas9	negative selection	1981417
54979318	54979341	5	+	26627737	HCT116	viability after 12 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	-0.2447241958559384	[678]	[367,234,292]	-3	hSpCas9	negative selection	2063728
54979350	54979373	5	+	26627737	HCT116	viability after 12 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	0.9281650954308303	[0]	[0,0,0]	7	hSpCas9	negative selection	2063729
54985376	54985399	5	+	26627737	HCT116	viability after 12 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	1.372561529367653	[359]	[441,373,654]	9	hSpCas9	negative selection	2063730
54985439	54985462	5	-	26627737	HCT116	viability after 12 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.10380172337119076	[778]	[299,421,428]	-1	hSpCas9	negative selection	2063731
54985443	54985466	5	+	26627737	HCT116	viability after 12 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	-0.4785689552158866	[707]	[277,343,179]	-5	hSpCas9	negative selection	2063732
54979318	54979341	5	+	26627737	HCT116	viability after 15 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	-0.42310645797996715	[678]	[353,303,222]	-4	hSpCas9	negative selection	2146043
54979350	54979373	5	+	26627737	HCT116	viability after 15 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	0.8001368291432343	[0]	[0,0,0]	7	hSpCas9	negative selection	2146044
54985376	54985399	5	+	26627737	HCT116	viability after 15 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	1.0497547072326934	[359]	[393,468,416]	8	hSpCas9	negative selection	2146045
54985439	54985462	5	-	26627737	HCT116	viability after 15 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.20699184955813799	[778]	[605,346,605]	2	hSpCas9	negative selection	2146046
54985443	54985466	5	+	26627737	HCT116	viability after 15 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	-0.591157282533159	[707]	[252,312,241]	-6	hSpCas9	negative selection	2146047
54979318	54979341	5	+	26627737	HCT116	viability after 18 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.1315393613377418	[678]	[398,238,452]	1	hSpCas9	negative selection	2228358
54979350	54979373	5	+	26627737	HCT116	viability after 18 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	1.0485523756554223	[0]	[0,0,0]	7	hSpCas9	negative selection	2228359
54985376	54985399	5	+	26627737	HCT116	viability after 18 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	1.3170049222614075	[359]	[420,334,556]	8	hSpCas9	negative selection	2228360
54985439	54985462	5	-	26627737	HCT116	viability after 18 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.13226089771199612	[778]	[399,284,349]	-1	hSpCas9	negative selection	2228361
54985443	54985466	5	+	26627737	HCT116	viability after 18 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	-0.06393999422620911	[707]	[346,347,283]	0	hSpCas9	negative selection	2228362
55013336	55013359	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCAGGAAGCTCAAACTGGGTGG	ESM1	ENSG00000164283	-1.2834902115453883	[110,41]	[9,2]	-7	dCas9-VP64	positive selection	2421808
54985685	54985708	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAACAAGAGAGCCTGGCAGGAGG	ESM1	ENSG00000164283	0.532238789517792	[58,282]	[71,35]	2	dCas9-VP64	positive selection	2441083
54985710	54985733	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTTTATGAAATCCAGGATGAAGG	ESM1	ENSG00000164283	3.9799111231550257	[8,4]	[8,42]	9	dCas9-VP64	positive selection	2441084
54985738	54985761	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTAACACGCTGCTGCCATCCAGG	ESM1	ENSG00000164283	-1.0102314338243301	[394,119]	[45,6]	-6	dCas9-VP64	positive selection	2441085
55013336	55013359	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCAGGAAGCTCAAACTGGGTGG	ESM1	ENSG00000164283	-0.4862249962475964	[248,57]	[62,10]	-5	dCas9-VP64	positive selection	2517063
54985685	54985708	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAACAAGAGAGCCTGGCAGGAGG	ESM1	ENSG00000164283	5.042767833169701	[100,46]	[1648,14]	9	dCas9-VP64	positive selection	2536338
54985710	54985733	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTTTATGAAATCCAGGATGAAGG	ESM1	ENSG00000164283	-0.12107555019341465	[30,39]	[9,10]	-1	dCas9-VP64	positive selection	2536339
54985738	54985761	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTAACACGCTGCTGCCATCCAGG	ESM1	ENSG00000164283	-1.402119868136817	[74,289]	[12,29]	-9	dCas9-VP64	positive selection	2536340
54985376	54985399	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCACTGTCCTCTTGCAGCGCGG	ESM1	ENSG00000164283	0.17544601314047986	[3,3]	[3,2]	4	hSpCas9	positive selection	2986420
54985466	54985489	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCGTGCCTGCACACCTGGTGG	ESM1	ENSG00000164283	0.07503513766840404	[3,3]	[3,3]	1	hSpCas9	positive selection	2986421
54985376	54985399	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCACTGTCCTCTTGCAGCGCGG	ESM1	ENSG00000164283	-0.6877160165020502	[3,3]	[1,0]	-8	hSpCas9	positive selection	3054278
54985466	54985489	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCGTGCCTGCACACCTGGTGG	ESM1	ENSG00000164283	-0.25658644834891053	[3,3]	[3,1]	-4	hSpCas9	positive selection	3054279
54979341	54979364		+	24336571	A375	resistance to PLX after 7 days	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	-0.041233384729485026	[13,13]	[14,11]	-1	hSpCas9	positive selection	3112556
54985440	54985463		+	24336571	A375	resistance to PLX after 7 days	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	-0.2886446039401704	[14,15]	[11,13]	-8	hSpCas9	positive selection	3112557
54985442	54985465		-	24336571	A375	resistance to PLX after 7 days	CGCCTGGAGCAATAATTATGCGG	ESM1	ENSG00000164283	-0.061779580158666136	[15,17]	[13,17]	-2	hSpCas9	positive selection	3112558
54979369	54979392		-	24336571	A375	resistance to PLX after 7 days	GTTGTGAAAGAGAATGCTGCCGG	ESM1	ENSG00000164283	0.11194868213589015	[5,4]	[5,5]	4	hSpCas9	positive selection	3112559
54979424	54979447		-	24336571	A375	resistance to PLX after 7 days	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.2368851984086362	[5,7]	[7,8]	7	hSpCas9	positive selection	3112560
54985339	54985362		-	24336571	A375	resistance to PLX after 7 days	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	-0.010501426437278916	[58,54]	[56,55]	0	hSpCas9	positive selection	3112561
54979341	54979364		+	24336571	A375	resistance to PLX after 14 days	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	1.4047322745601172	[17,18]	[21,22]	8	hSpCas9	positive selection	3170349
54985440	54985463		+	24336571	A375	resistance to PLX after 14 days	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.13929425383130262	[15,13]	[6,7]	1	hSpCas9	positive selection	3170350
54985442	54985465		-	24336571	A375	resistance to PLX after 14 days	CGCCTGGAGCAATAATTATGCGG	ESM1	ENSG00000164283	-0.7464479879877096	[20,15]	[3,4]	-8	hSpCas9	positive selection	3170351
54979369	54979392		-	24336571	A375	resistance to PLX after 14 days	GTTGTGAAAGAGAATGCTGCCGG	ESM1	ENSG00000164283	0.11567357505202369	[3,8]	[2,2]	1	hSpCas9	positive selection	3170352
54979424	54979447		-	24336571	A375	resistance to PLX after 14 days	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.5170506137356767	[4,4]	[2,2]	5	hSpCas9	positive selection	3170353
54985339	54985362		-	24336571	A375	resistance to PLX after 14 days	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	-0.6225465831005395	[47,54]	[13,16]	-7	hSpCas9	positive selection	3170354
54979341	54979364		+	24336571	A375	viability after 7 days	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	-0.8696368399969745	[26]	[13,13]	-8	hSpCas9	negative selection	3228142
54985440	54985463		+	24336571	A375	viability after 7 days	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.2745448634445614	[13]	[14,15]	4	hSpCas9	negative selection	3228143
54985442	54985465		-	24336571	A375	viability after 7 days	CGCCTGGAGCAATAATTATGCGG	ESM1	ENSG00000164283	0.18140424598228647	[15]	[15,17]	2	hSpCas9	negative selection	3228144
54979369	54979392		-	24336571	A375	viability after 7 days	GTTGTGAAAGAGAATGCTGCCGG	ESM1	ENSG00000164283	-0.36533037358239706	[7]	[5,4]	-5	hSpCas9	negative selection	3228145
54979424	54979447		-	24336571	A375	viability after 7 days	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	-1.456529426711556	[20]	[5,7]	-9	hSpCas9	negative selection	3228146
54985339	54985362		-	24336571	A375	viability after 7 days	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.4191583200768272	[44]	[58,54]	6	hSpCas9	negative selection	3228147
54979341	54979364		+	24336571	A375	viability after 14 days	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	-0.474330676434943	[26]	[17,18]	-5	hSpCas9	negative selection	3285935
54985440	54985463		+	24336571	A375	viability after 14 days	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.22744906796561132	[13]	[15,13]	3	hSpCas9	negative selection	3285936
54985442	54985465		-	24336571	A375	viability after 14 days	CGCCTGGAGCAATAATTATGCGG	ESM1	ENSG00000164283	0.3111047652176133	[15]	[20,15]	4	hSpCas9	negative selection	3285937
54979369	54979392		-	24336571	A375	viability after 14 days	GTTGTGAAAGAGAATGCTGCCGG	ESM1	ENSG00000164283	-0.1678130808873134	[7]	[3,8]	-2	hSpCas9	negative selection	3285938
54979424	54979447		-	24336571	A375	viability after 14 days	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	-1.8283713423203727	[20]	[4,4]	-9	hSpCas9	negative selection	3285939
54985339	54985362		-	24336571	A375	viability after 14 days	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.2863830973869401	[44]	[47,54]	4	hSpCas9	negative selection	3285940
54985339	54985362	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.49720965302907216	[91,124]	[0,0]	2	hSpCas9	positive selection	3348391
54985440	54985463	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.16993270553329048	[134,136]	[0,0]	0	hSpCas9	positive selection	3348392
54982109	54982132	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	1.5706426011353545	[209,201]	[0,6]	6	hSpCas9	positive selection	3348393
54982089	54982112	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	-0.37929840909781365	[198,198]	[0,0]	-2	hSpCas9	positive selection	3367597
54979424	54979447	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.19123702098806272	[133,133]	[0,0]	1	hSpCas9	positive selection	3367598
54979341	54979364	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	-1.4326717599736103	[412,412]	[0,0]	-8	hSpCas9	positive selection	3367599
54985375	54985398	5	+	26780180	HT29	viability (Avana library 4 designs)	AGCACTGTCCTCTTGCAGCGCGG	ESM1	ENSG00000164283	1.27297696683282	[]	[]	5	hSpCas9	negative selection	3423249
54985412	54985435	5	+	26780180	HT29	viability (Avana library 4 designs)	CACTGCTGTCACAGTGTTGAGGG	ESM1	ENSG00000164283	0.0687968269940118	[]	[]	0	hSpCas9	negative selection	3423250
54985466	54985489	5	-	26780180	HT29	viability (Avana library 4 designs)	CCTCGTGCCTGCACACCTGGTGG	ESM1	ENSG00000164283	0.520563216011439	[]	[]	2	hSpCas9	negative selection	3423251
54985338	54985361	5	-	26780180	HT29	viability (Avana library 4 designs)	GCTGCCGAGTGTGCGCTGCAGGG	ESM1	ENSG00000164283	0.609811929581378	[]	[]	2	hSpCas9	negative selection	3423252
54985412	54985435	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CACTGCTGTCACAGTGTTGAGGG	ESM1	ENSG00000164283	5.92807877333206	[]	[]	9	hSpCas9	negative selection	3504316
54985338	54985361	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCGAGTGTGCGCTGCAGGG	ESM1	ENSG00000164283	6.60322091638811	[]	[]	9	hSpCas9	negative selection	3504317
54985375	54985398	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCACTGTCCTCTTGCAGCGCGG	ESM1	ENSG00000164283	4.29967233966299	[]	[]	7	hSpCas9	negative selection	3504318
54985466	54985489	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCGTGCCTGCACACCTGGTGG	ESM1	ENSG00000164283	2.46786155195786	[]	[]	3	hSpCas9	negative selection	3504319
54985412	54985435	5	+	26780180	A375	viability (Avana lentiGuide)	CACTGCTGTCACAGTGTTGAGGG	ESM1	ENSG00000164283	-2.39387452726958	[]	[]	-4	hSpCas9	negative selection	3612975
54985338	54985361	5	-	26780180	A375	viability (Avana lentiGuide)	GCTGCCGAGTGTGCGCTGCAGGG	ESM1	ENSG00000164283	4.46119470844971	[]	[]	4	hSpCas9	negative selection	3612976
54985375	54985398	5	+	26780180	A375	viability (Avana lentiGuide)	AGCACTGTCCTCTTGCAGCGCGG	ESM1	ENSG00000164283	1.76981538081988	[]	[]	2	hSpCas9	negative selection	3612977
54985466	54985489	5	-	26780180	A375	viability (Avana lentiGuide)	CCTCGTGCCTGCACACCTGGTGG	ESM1	ENSG00000164283	-2.1498133242667	[]	[]	-4	hSpCas9	negative selection	3612978
54985412	54985435	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACTGCTGTCACAGTGTTGAGGG	ESM1	ENSG00000164283	0.20763428597778447	[5]	[6,6]	6	hSpCas9	positive selection	3721634
54985338	54985361	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCGAGTGTGCGCTGCAGGG	ESM1	ENSG00000164283	0.35194372892751397	[4]	[5,5]	9	hSpCas9	positive selection	3721635
54985375	54985398	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCACTGTCCTCTTGCAGCGCGG	ESM1	ENSG00000164283	0.09258120423798674	[4]	[5,4]	2	hSpCas9	positive selection	3721636
54985466	54985489	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCGTGCCTGCACACCTGGTGG	ESM1	ENSG00000164283	0.17817848643207154	[4]	[5,5]	5	hSpCas9	positive selection	3721637
54985412	54985435	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACTGCTGTCACAGTGTTGAGGG	ESM1	ENSG00000164283	0.4234890973750659	[5]	[6,5]	9	hSpCas9	positive selection	3830241
54985338	54985361	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCGAGTGTGCGCTGCAGGG	ESM1	ENSG00000164283	-0.600806988213725	[5]	[2,2]	-6	hSpCas9	positive selection	3830242
54985375	54985398	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCACTGTCCTCTTGCAGCGCGG	ESM1	ENSG00000164283	-0.4747464131784681	[5]	[1,4]	-6	hSpCas9	positive selection	3830243
54985466	54985489	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCGTGCCTGCACACCTGGTGG	ESM1	ENSG00000164283	0.2369925991177848	[5]	[6,5]	6	hSpCas9	positive selection	3830244
54979341	54979364	5	+	26780180	A375	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	-0.00326634986672208	[]	[]	0	hSpCas9	negative selection	3937586
54985440	54985463	5	+	26780180	A375	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.609794153494852	[]	[]	2	hSpCas9	negative selection	3937587
54982109	54982132	5	+	26780180	A375	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.427429357201195	[]	[]	1	hSpCas9	negative selection	3937588
54982089	54982112	5	-	26780180	A375	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.978991771961519	[]	[]	4	hSpCas9	negative selection	3937589
54979424	54979447	5	-	26780180	A375	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.538834609371115	[]	[]	1	hSpCas9	negative selection	3937590
54985339	54985362	5	-	26780180	A375	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.998609198259758	[]	[]	4	hSpCas9	negative selection	3937591
54979341	54979364	5	+	26780180	HT29	viability (GeCKOv2 library)	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	-0.015232328840845	[]	[]	0	hSpCas9	negative selection	4045552
54985440	54985463	5	+	26780180	HT29	viability (GeCKOv2 library)	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	1.12308871364482	[]	[]	5	hSpCas9	negative selection	4045553
54982109	54982132	5	+	26780180	HT29	viability (GeCKOv2 library)	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.239446350166222	[]	[]	0	hSpCas9	negative selection	4045554
54982089	54982112	5	-	26780180	HT29	viability (GeCKOv2 library)	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.960857516210745	[]	[]	4	hSpCas9	negative selection	4045555
54979424	54979447	5	-	26780180	HT29	viability (GeCKOv2 library)	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.678362627705805	[]	[]	2	hSpCas9	negative selection	4045556
54985339	54985362	5	-	26780180	HT29	viability (GeCKOv2 library)	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	1.07791140658069	[]	[]	5	hSpCas9	negative selection	4045557
54979341	54979364	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.5499869862122396	[3]	[2,4]	9	hSpCas9	positive selection	4135288
54985440	54985463	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.03538469628732766	[3]	[2,2]	0	hSpCas9	positive selection	4135289
54985442	54985465	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCTGGAGCAATAATTATGCGG	ESM1	ENSG00000164283	0.5040439120733246	[3]	[3,2]	9	hSpCas9	positive selection	4135290
54979369	54979392	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTGTGAAAGAGAATGCTGCCGG	ESM1	ENSG00000164283	-0.15705901830558638	[2]	[1,1]	-4	hSpCas9	positive selection	4135291
54979424	54979447	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	-0.16263700035290057	[2]	[1,1]	-4	hSpCas9	positive selection	4135292
54985339	54985362	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.5109646312952518	[5]	[7,3]	9	hSpCas9	positive selection	4135293
54979341	54979364	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.5988575268198004	[4]	[4,5,5,0]	4	hSpCas9	positive selection	4199310
54985440	54985463	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.2326118809950024	[3]	[3,0,4,0]	1	hSpCas9	positive selection	4199311
54985442	54985465	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCTGGAGCAATAATTATGCGG	ESM1	ENSG00000164283	-0.28590901831635623	[3]	[3,0,0,0]	-4	hSpCas9	positive selection	4199312
54979369	54979392	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTGTGAAAGAGAATGCTGCCGG	ESM1	ENSG00000164283	-0.42803890134224637	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4199313
54979424	54979447	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.8338376750600387	[3]	[1,0,2,4]	5	hSpCas9	positive selection	4199314
54985339	54985362	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.902825629414543	[5]	[4,3,3,5]	6	hSpCas9	positive selection	4199315
54985339	54985362	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.1839632186260679	[2]	[3,0]	3	hSpCas9	positive selection	4269258
54985440	54985463	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.4696183251371355	[3]	[4,3]	8	hSpCas9	positive selection	4269259
54982109	54982132	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.33900664622057886	[3]	[4,3]	7	hSpCas9	positive selection	4269260
54982089	54982112	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	-0.08071539438524775	[2]	[2,1]	-1	hSpCas9	positive selection	4333523
54979424	54979447	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	-0.021166080698082707	[2]	[2,1]	0	hSpCas9	positive selection	4333524
54979341	54979364	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.5951239633763592	[3]	[4,4]	9	hSpCas9	positive selection	4333525
54985250	54985272	5	-	27760321	OCIAML3	viability	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	-0.22645449542457108	[484,456]	[361,253]	-2	hSpCas9	negative selection	4398410
54985285	54985307	5	-	27760321	OCIAML3	viability	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.765195684575326	[631,501]	[620,915]	8	hSpCas9	negative selection	4398411
54985301	54985323	5	-	27760321	OCIAML3	viability	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	-0.002126307050902554	[929,718]	[620,662]	0	hSpCas9	negative selection	4398412
54985339	54985361	5	-	27760321	OCIAML3	viability	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	-0.013523476337773399	[1088,1031]	[812,834]	0	hSpCas9	negative selection	4398413
54985363	54985385	5	-	27760321	OCIAML3	viability	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	0.5593190206722674	[951,762]	[939,1037]	6	hSpCas9	negative selection	4398414
54985250	54985272	5	-	27760321	OCIAML2	viability	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	0.4532239075455753	[484,456]	[424,649]	6	hSpCas9	negative selection	4481873
54985285	54985307	5	-	27760321	OCIAML2	viability	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.9380249612466327	[631,501]	[730,1060]	9	hSpCas9	negative selection	4481874
54985301	54985323	5	-	27760321	OCIAML2	viability	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.4141303704306465	[929,718]	[748,1057]	5	hSpCas9	negative selection	4481875
54985339	54985361	5	-	27760321	OCIAML2	viability	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.12528680879232668	[1088,1031]	[827,1079]	1	hSpCas9	negative selection	4481876
54985363	54985385	5	-	27760321	OCIAML2	viability	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	0.34461021117912227	[951,762]	[908,831]	5	hSpCas9	negative selection	4481877
54985250	54985272	5	-	27760321	MV411	viability	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	1.403644168496225	[484,456]	[593,1166]	8	hSpCas9	negative selection	4565336
54985285	54985307	5	-	27760321	MV411	viability	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.9762053426077058	[631,501]	[944,410]	7	hSpCas9	negative selection	4565337
54985301	54985323	5	-	27760321	MV411	viability	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	-0.24814690537127793	[929,718]	[216,811]	-2	hSpCas9	negative selection	4565338
54985339	54985361	5	-	27760321	MV411	viability	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.13298761776509105	[1088,1031]	[561,1077]	0	hSpCas9	negative selection	4565339
54985363	54985385	5	-	27760321	MV411	viability	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	1.1404117029806133	[951,762]	[1031,1552]	8	hSpCas9	negative selection	4565340
54985250	54985272	5	-	27760321	HL60	viability	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	0.23863300484916664	[484,456]	[564,336]	3	hSpCas9	negative selection	4648799
54985285	54985307	5	-	27760321	HL60	viability	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	1.0982821696178509	[631,501]	[1020,947]	9	hSpCas9	negative selection	4648800
54985301	54985323	5	-	27760321	HL60	viability	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.5288582940141853	[929,718]	[938,991]	6	hSpCas9	negative selection	4648801
54985339	54985361	5	-	27760321	HL60	viability	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.5205249959345228	[1088,1031]	[1045,1453]	6	hSpCas9	negative selection	4648802
54985363	54985385	5	-	27760321	HL60	viability	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	0.5708036492335504	[951,762]	[1181,877]	6	hSpCas9	negative selection	4648803
54985250	54985272	5	-	27760321	HT1080	viability	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	0.19183366280451053	[456,356]	[178,191]	0	hSpCas9	negative selection	4732262
54985285	54985307	5	-	27760321	HT1080	viability	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.7171942063017449	[501,391]	[255,332]	4	hSpCas9	negative selection	4732263
54985301	54985323	5	-	27760321	HT1080	viability	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.5151573083414306	[718,560]	[213,528]	2	hSpCas9	negative selection	4732264
54985339	54985361	5	-	27760321	HT1080	viability	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.033665753286939104	[1031,804]	[332,419]	0	hSpCas9	negative selection	4732265
54985363	54985385	5	-	27760321	HT1080	viability	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	0.9750339752039762	[762,595]	[460,609]	5	hSpCas9	negative selection	4732266
54985250	54985272	5	-	27760321	HT29	viability after 7 days	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	0.273016393109178	[456,356]	[569,868,453]	4	hSpCas9	negative selection	4815725
54985285	54985307	5	-	27760321	HT29	viability after 7 days	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.7013273475038564	[501,391]	[1166,595,1067]	9	hSpCas9	negative selection	4815726
54985301	54985323	5	-	27760321	HT29	viability after 7 days	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.37463431533353553	[718,560]	[1563,1089,629]	6	hSpCas9	negative selection	4815727
54985339	54985361	5	-	27760321	HT29	viability after 7 days	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.3208764827270909	[1031,804]	[1541,1303,1582]	5	hSpCas9	negative selection	4815728
54985363	54985385	5	-	27760321	HT29	viability after 7 days	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	0.4536890303433906	[762,595]	[1208,1225,1155]	7	hSpCas9	negative selection	4815729
54985250	54985272	5	-	27760321	HT29	viability after 25 days	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	0.3265164044790843	[456,356]	[557,467,740]	3	hSpCas9	negative selection	4899188
54985285	54985307	5	-	27760321	HT29	viability after 25 days	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	1.0786586055988285	[501,391]	[864,845,1590]	9	hSpCas9	negative selection	4899189
54985301	54985323	5	-	27760321	HT29	viability after 25 days	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.5266926220857248	[718,560]	[1225,795,1134]	6	hSpCas9	negative selection	4899190
54985339	54985361	5	-	27760321	HT29	viability after 25 days	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.29888942593241685	[1031,804]	[1351,1250,1261]	3	hSpCas9	negative selection	4899191
54985363	54985385	5	-	27760321	HT29	viability after 25 days	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	0.6562601499894706	[762,595]	[1096,1277,1311]	7	hSpCas9	negative selection	4899192
54985250	54985272	5	-	27760321	HT29	viability after 22 days	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	0.45983257386102167	[456,356]	[672,493,774]	5	hSpCas9	negative selection	4982651
54985285	54985307	5	-	27760321	HT29	viability after 22 days	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	1.014950054019994	[501,391]	[1251,858,1015]	9	hSpCas9	negative selection	4982652
54985301	54985323	5	-	27760321	HT29	viability after 22 days	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.7751443614781698	[718,560]	[1490,1073,1226]	8	hSpCas9	negative selection	4982653
54985339	54985361	5	-	27760321	HT29	viability after 22 days	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.229740193289794	[1031,804]	[1272,1263,1196]	2	hSpCas9	negative selection	4982654
54985363	54985385	5	-	27760321	HT29	viability after 22 days	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	0.6293645639899789	[762,595]	[1125,1196,1325]	7	hSpCas9	negative selection	4982655
54985250	54985272	5	-	27760321	HT29	viability after 19 days	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	0.48876366281272815	[456,356]	[594,594,758]	5	hSpCas9	negative selection	5066114
54985285	54985307	5	-	27760321	HT29	viability after 19 days	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.6792122736141089	[501,391]	[1010,525,933]	7	hSpCas9	negative selection	5066115
54985301	54985323	5	-	27760321	HT29	viability after 19 days	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.8035441572557095	[718,560]	[1613,1111,1145]	8	hSpCas9	negative selection	5066116
54985339	54985361	5	-	27760321	HT29	viability after 19 days	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.21888410571046202	[1031,804]	[1251,904,1501]	2	hSpCas9	negative selection	5066117
54985363	54985385	5	-	27760321	HT29	viability after 19 days	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	0.32906583559476277	[762,595]	[989,1482,475]	3	hSpCas9	negative selection	5066118
54985250	54985272	5	-	27760321	HT29	viability after 16 days	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	0.30622545215987873	[456,356]	[395,689,583]	3	hSpCas9	negative selection	5149577
54985285	54985307	5	-	27760321	HT29	viability after 16 days	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.575238060290987	[501,391]	[934,677,641]	6	hSpCas9	negative selection	5149578
54985301	54985323	5	-	27760321	HT29	viability after 16 days	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.7247035254993549	[718,560]	[1406,905,1264]	8	hSpCas9	negative selection	5149579
54985339	54985361	5	-	27760321	HT29	viability after 16 days	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.39571988195167584	[1031,804]	[1697,974,1424]	4	hSpCas9	negative selection	5149580
54985363	54985385	5	-	27760321	HT29	viability after 16 days	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	0.31196657629601166	[762,595]	[1177,880,795]	3	hSpCas9	negative selection	5149581
54985250	54985272	5	-	27760321	HT29	viability after 13 days	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	0.37168029385240736	[456,356]	[656,485,684]	5	hSpCas9	negative selection	5233040
54985285	54985307	5	-	27760321	HT29	viability after 13 days	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.8558247792129243	[501,391]	[973,811,1023]	9	hSpCas9	negative selection	5233041
54985301	54985323	5	-	27760321	HT29	viability after 13 days	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.8168120557056237	[718,560]	[1422,1583,938]	9	hSpCas9	negative selection	5233042
54985339	54985361	5	-	27760321	HT29	viability after 13 days	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.40430134294778686	[1031,804]	[1370,1920,965]	5	hSpCas9	negative selection	5233043
54985363	54985385	5	-	27760321	HT29	viability after 13 days	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	0.5364335627557734	[762,595]	[1357,1056,1021]	7	hSpCas9	negative selection	5233044
54985250	54985272	5	-	27760321	HT29	viability after 10 days	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	0.007704623679664374	[456,356]	[581,445,502]	0	hSpCas9	negative selection	5316503
54985285	54985307	5	-	27760321	HT29	viability after 10 days	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.601189479701923	[501,391]	[869,919,753]	7	hSpCas9	negative selection	5316504
54985301	54985323	5	-	27760321	HT29	viability after 10 days	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.7489279315429734	[718,560]	[1314,1688,1040]	8	hSpCas9	negative selection	5316505
54985339	54985361	5	-	27760321	HT29	viability after 10 days	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.07305772407764466	[1031,804]	[1310,1203,1105]	0	hSpCas9	negative selection	5316506
54985363	54985385	5	-	27760321	HT29	viability after 10 days	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	0.35857141148948746	[762,595]	[912,1219,1132]	5	hSpCas9	negative selection	5316507
54985250	54985272	5	-	27760321	MOLM13	viability	TGTCAGCCTTCTAATGGGGAGG	ESM1	ENSG00000164283	0.369278304284135	[484,456]	[268,406]	2	hSpCas9	negative selection	5399966
54985285	54985307	5	-	27760321	MOLM13	viability	GCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	1.9248771729261385	[631,501]	[2259,310]	9	hSpCas9	negative selection	5399967
54985301	54985323	5	-	27760321	MOLM13	viability	TACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.7405006033409476	[929,718]	[877,680]	5	hSpCas9	negative selection	5399968
54985339	54985361	5	-	27760321	MOLM13	viability	GCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.4157472876701125	[1088,1031]	[986,638]	3	hSpCas9	negative selection	5399969
54985363	54985385	5	-	27760321	MOLM13	viability	GGACAGTGCTCGACGACTGTGG	ESM1	ENSG00000164283	0.9690140040418345	[951,762]	[1222,701]	7	hSpCas9	negative selection	5399970
54985170	54985193	5	+	27661255	K562	viability	GCTCTCAGCATGCCCCGGGAGGG	ESM1	ENSG00000164283	-0.5108671915196834	[158,196]	[120,80]	-7	dCas9-KRAB	negative selection	5477899
54985181	54985204	5	+	27661255	K562	viability	GCCCCGGGAGGGGAGAGGTAAGG	ESM1	ENSG00000164283	0.47698953960748947	[256,272]	[323,268]	9	dCas9-KRAB	negative selection	5477900
54985253	54985276	5	-	27661255	K562	viability	GAGGTGTCAGCCTTCTAATGGGG	ESM1	ENSG00000164283	0.016135599774490084	[922,977]	[881,668]	0	dCas9-KRAB	negative selection	5477901
54985339	54985362	5	-	27260156	BXPC3	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.1633746280102517	[293]	[296,288,446,352]	3	hSpCas9	negative selection	5541718
54985440	54985463	5	+	27260156	BXPC3	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.2672941442215165	[523]	[636,666,589,750]	6	hSpCas9	negative selection	5541719
54982109	54982132	5	+	27260156	BXPC3	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.05039683611329615	[831]	[776,981,1032,803]	1	hSpCas9	negative selection	5541720
54982089	54982112	5	-	27260156	BXPC3	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.1875245434818465	[330]	[295,396,450,447]	4	hSpCas9	negative selection	5605983
54979424	54979447	5	-	27260156	BXPC3	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.25144055616842037	[295]	[222,502,328,430]	5	hSpCas9	negative selection	5605984
54979341	54979364	5	+	27260156	BXPC3	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.6198180095549779	[784]	[1049,1289,1336,1398]	9	hSpCas9	negative selection	5605985
54985339	54985362	5	-	27260156	A673	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.25132384632890653	[293]	[490,390,403,401]	6	hSpCas9	negative selection	5662969
54985440	54985463	5	+	27260156	A673	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.002318143564649655	[523]	[667,555,560,747]	0	hSpCas9	negative selection	5662970
54982109	54982132	5	+	27260156	A673	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.2429072324349446	[831]	[1377,1155,1020,1196]	6	hSpCas9	negative selection	5662971
54982089	54982112	5	-	27260156	A673	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.13250704605040498	[330]	[566,462,343,379]	3	hSpCas9	negative selection	5727234
54979424	54979447	5	-	27260156	A673	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.20381979739187772	[295]	[509,400,359,375]	5	hSpCas9	negative selection	5727235
54979341	54979364	5	+	27260156	A673	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.6224190278860329	[784]	[1544,1419,1315,1537]	9	hSpCas9	negative selection	5727236
54985339	54985362	5	-	27260156	A375	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.1515137553305107	[293]	[432,418,316,362]	2	hSpCas9	negative selection	5784220
54985440	54985463	5	+	27260156	A375	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.550590452298932	[523]	[938,1118,737,825]	7	hSpCas9	negative selection	5784221
54982109	54982132	5	+	27260156	A375	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.3167005796424107	[831]	[1300,1519,1169,923]	4	hSpCas9	negative selection	5784222
54982089	54982112	5	-	27260156	A375	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.10710105296070777	[330]	[322,610,419,344]	1	hSpCas9	negative selection	5848485
54979424	54979447	5	-	27260156	A375	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.3305769231105819	[295]	[378,501,501,370]	5	hSpCas9	negative selection	5848486
54979341	54979364	5	+	27260156	A375	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.9853028351481268	[784]	[2162,1887,1776,1478]	9	hSpCas9	negative selection	5848487
54985339	54985362	5	-	27260156	COLO741	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.6629836747338129	[293]	[682,577,533]	9	hSpCas9	negative selection	5905471
54985440	54985463	5	+	27260156	COLO741	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.22068369522443504	[523]	[787,806,746]	4	hSpCas9	negative selection	5905472
54982109	54982132	5	+	27260156	COLO741	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.3574719393541437	[831]	[1242,1523,1309]	7	hSpCas9	negative selection	5905473
54982089	54982112	5	-	27260156	COLO741	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	-0.02084832971953643	[330]	[410,488,353]	0	hSpCas9	negative selection	5969736
54979424	54979447	5	-	27260156	COLO741	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.4743111167474159	[295]	[672,384,528]	8	hSpCas9	negative selection	5969737
54979341	54979364	5	+	27260156	COLO741	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.8183463574197238	[784]	[1975,1543,1796]	9	hSpCas9	negative selection	5969738
54985339	54985362	5	-	27260156	CAL120	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.2805487426940122	[293]	[598,467,291]	4	hSpCas9	negative selection	6026722
54985440	54985463	5	+	27260156	CAL120	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.2515432311461749	[523]	[707,822,786]	4	hSpCas9	negative selection	6026723
54982109	54982132	5	+	27260156	CAL120	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.5287346236336925	[831]	[1908,1096,1535]	7	hSpCas9	negative selection	6026724
54982089	54982112	5	-	27260156	CAL120	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	-0.260444439117562	[330]	[249,293,470]	-4	hSpCas9	negative selection	6090987
54979424	54979447	5	-	27260156	CAL120	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.08899223173953574	[295]	[679,284,255]	1	hSpCas9	negative selection	6090988
54979341	54979364	5	+	27260156	CAL120	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.5804933981465097	[784]	[1464,1610,1308]	8	hSpCas9	negative selection	6090989
54985339	54985362	5	-	27260156	CADOES1	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.5364104796711502	[293]	[308,467,277,536]	8	hSpCas9	negative selection	6147973
54985440	54985463	5	+	27260156	CADOES1	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.3489407730874798	[523]	[684,633,585,575]	6	hSpCas9	negative selection	6147974
54982109	54982132	5	+	27260156	CADOES1	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.3204368046642272	[831]	[1010,925,1135,784]	5	hSpCas9	negative selection	6147975
54982089	54982112	5	-	27260156	CADOES1	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.3196865190854181	[330]	[320,185,429,607]	5	hSpCas9	negative selection	6212238
54979424	54979447	5	-	27260156	CADOES1	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	-0.019680564603824835	[295]	[257,247,263,317]	0	hSpCas9	negative selection	6212239
54979341	54979364	5	+	27260156	CADOES1	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.8403847136493023	[784]	[1080,1248,1347,1560]	9	hSpCas9	negative selection	6212240
54985339	54985362	5	-	27260156	EWS502	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.4475158521078563	[293]	[404,482,389,417]	7	hSpCas9	negative selection	6269224
54985440	54985463	5	+	27260156	EWS502	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.02974845750697641	[523]	[637,632,614,351]	0	hSpCas9	negative selection	6269225
54982109	54982132	5	+	27260156	EWS502	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.13465889737886638	[831]	[932,864,1052,1028]	2	hSpCas9	negative selection	6269226
54982089	54982112	5	-	27260156	EWS502	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.0544941630005954	[330]	[307,398,367,386]	0	hSpCas9	negative selection	6333489
54979424	54979447	5	-	27260156	EWS502	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.17850492583335742	[295]	[259,467,366,327]	3	hSpCas9	negative selection	6333490
54979341	54979364	5	+	27260156	EWS502	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.783618807430555	[784]	[1243,1669,1354,1464]	9	hSpCas9	negative selection	6333491
54985339	54985362	5	-	27260156	EW8	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.3555843235958818	[293]	[352,332,287,252]	6	hSpCas9	negative selection	6390475
54985440	54985463	5	+	27260156	EW8	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.3351209328298709	[523]	[549,497,514,582]	6	hSpCas9	negative selection	6390476
54982109	54982132	5	+	27260156	EW8	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.08553756415036895	[831]	[719,783,647,719]	1	hSpCas9	negative selection	6390477
54982089	54982112	5	-	27260156	EW8	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	-0.12181212754439963	[330]	[185,356,224,214]	-2	hSpCas9	negative selection	6454740
54979424	54979447	5	-	27260156	EW8	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.17058692808971804	[295]	[336,216,223,315]	3	hSpCas9	negative selection	6454741
54979341	54979364	5	+	27260156	EW8	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.8360320936489483	[784]	[956,1382,1087,1100]	9	hSpCas9	negative selection	6454742
54985339	54985362	5	-	27260156	CORL105	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.5191531088705201	[293]	[419,614,404,513]	8	hSpCas9	negative selection	6511726
54985440	54985463	5	+	27260156	CORL105	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.23734064822527867	[523]	[849,549,842,675]	4	hSpCas9	negative selection	6511727
54982109	54982132	5	+	27260156	CORL105	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.16618210986237447	[831]	[1018,1147,1107,1094]	3	hSpCas9	negative selection	6511728
54982089	54982112	5	-	27260156	CORL105	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.4432158438336552	[330]	[599,369,773,407]	7	hSpCas9	negative selection	6575991
54979424	54979447	5	-	27260156	CORL105	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.2978746261899342	[295]	[426,379,409,484]	5	hSpCas9	negative selection	6575992
54979341	54979364	5	+	27260156	CORL105	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.5547838783561638	[784]	[1248,1228,1716,1260]	8	hSpCas9	negative selection	6575993
54985339	54985362	5	-	27260156	HS294T	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.8881145680803868	[293]	[347,171,161,133]	9	hSpCas9	negative selection	6632977
54985440	54985463	5	+	27260156	HS294T	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.3877345238884616	[523]	[346,271,157,275]	5	hSpCas9	negative selection	6632978
54982109	54982132	5	+	27260156	HS294T	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.3655416101706843	[831]	[259,368,424,659]	5	hSpCas9	negative selection	6632979
54982089	54982112	5	-	27260156	HS294T	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.2392511192151261	[330]	[169,123,101,217]	3	hSpCas9	negative selection	6697242
54979424	54979447	5	-	27260156	HS294T	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.13312202508965176	[295]	[59,195,96,157]	1	hSpCas9	negative selection	6697243
54979341	54979364	5	+	27260156	HS294T	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.25374616317136867	[784]	[420,344,293,384]	3	hSpCas9	negative selection	6697244
54985339	54985362	5	-	27260156	HCC44	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.46989119572190474	[293]	[361,683,450,303]	7	hSpCas9	negative selection	6754228
54985440	54985463	5	+	27260156	HCC44	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.22663652355713548	[523]	[931,557,856,496]	3	hSpCas9	negative selection	6754229
54982109	54982132	5	+	27260156	HCC44	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.2669248802902453	[831]	[904,1043,1574,1065]	4	hSpCas9	negative selection	6754230
54982089	54982112	5	-	27260156	HCC44	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.11789019785871385	[330]	[499,330,280,503]	1	hSpCas9	negative selection	6818493
54979424	54979447	5	-	27260156	HCC44	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.13545575428234802	[295]	[678,168,444,248]	2	hSpCas9	negative selection	6818494
54979341	54979364	5	+	27260156	HCC44	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.9389286139179223	[784]	[1993,1791,1649,1373]	9	hSpCas9	negative selection	6818495
54985339	54985362	5	-	27260156	G402	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.9823690744851992	[293]	[732,1151,700,295]	9	hSpCas9	negative selection	6875479
54985440	54985463	5	+	27260156	G402	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.6022579113667714	[523]	[1102,1210,671,927]	7	hSpCas9	negative selection	6875480
54982109	54982132	5	+	27260156	G402	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.6232521135525739	[831]	[1736,1407,1429,1683]	7	hSpCas9	negative selection	6875481
54982089	54982112	5	-	27260156	G402	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.1679871252954787	[330]	[516,589,431,298]	2	hSpCas9	negative selection	6939744
54979424	54979447	5	-	27260156	G402	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	-0.19764244290288535	[295]	[297,584,247,148]	-3	hSpCas9	negative selection	6939745
54979341	54979364	5	+	27260156	G402	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	1.2546596635471279	[784]	[2141,2639,2442,1925]	9	hSpCas9	negative selection	6939746
54985339	54985362	5	-	27260156	L33	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.4933092734842194	[293]	[492,124,265,431]	8	hSpCas9	negative selection	6996730
54985440	54985463	5	+	27260156	L33	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	-0.15156838037386203	[523]	[506,210,337,327]	-3	hSpCas9	negative selection	6996731
54982109	54982132	5	+	27260156	L33	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.3564854387965233	[831]	[974,455,730,1012]	7	hSpCas9	negative selection	6996732
54982089	54982112	5	-	27260156	L33	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.3999140641862666	[330]	[541,164,212,459]	8	hSpCas9	negative selection	7060995
54979424	54979447	5	-	27260156	L33	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	-0.09343876771763993	[295]	[199,148,198,231]	-2	hSpCas9	negative selection	7060996
54979341	54979364	5	+	27260156	L33	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.3532551940280917	[784]	[940,398,725,943]	7	hSpCas9	negative selection	7060997
54985339	54985362	5	-	27260156	K562	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.3702680693353942	[293]	[584,315,319,165]	5	hSpCas9	negative selection	7117981
54985440	54985463	5	+	27260156	K562	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.2477201899097375	[523]	[601,606,535,476]	3	hSpCas9	negative selection	7117982
54982109	54982132	5	+	27260156	K562	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.26896857573172395	[831]	[766,1011,955,823]	3	hSpCas9	negative selection	7117983
54982089	54982112	5	-	27260156	K562	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	-0.40456096060874414	[330]	[295,200,175,218]	-5	hSpCas9	negative selection	7182246
54979424	54979447	5	-	27260156	K562	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.3420952509074072	[295]	[454,653,185,90]	4	hSpCas9	negative selection	7182247
54979341	54979364	5	+	27260156	K562	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.7133469565254433	[784]	[1415,988,754,1388]	8	hSpCas9	negative selection	7182248
54985339	54985362	5	-	27260156	HT29	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.11998218657542503	[293]	[364,339,345,481]	2	hSpCas9	negative selection	7239232
54985440	54985463	5	+	27260156	HT29	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.09475846108023639	[523]	[1004,659,607,489]	1	hSpCas9	negative selection	7239233
54982109	54982132	5	+	27260156	HT29	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.32095916295467797	[831]	[1190,1437,1378,1069]	6	hSpCas9	negative selection	7239234
54982089	54982112	5	-	27260156	HT29	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.36043545914378067	[330]	[567,695,544,299]	7	hSpCas9	negative selection	7303497
54979424	54979447	5	-	27260156	HT29	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.19098022691424488	[295]	[498,340,364,432]	4	hSpCas9	negative selection	7303498
54979341	54979364	5	+	27260156	HT29	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.6835891393400837	[784]	[1802,1600,1468,1301]	9	hSpCas9	negative selection	7303499
54985339	54985362	5	-	27260156	MHHES1	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.6775063303217497	[293]	[600,539,433,537]	9	hSpCas9	negative selection	7360483
54985440	54985463	5	+	27260156	MHHES1	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.07916624603704825	[523]	[619,639,741,506]	1	hSpCas9	negative selection	7360484
54982109	54982132	5	+	27260156	MHHES1	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.055600469559440646	[831]	[1075,1139,1007,734]	1	hSpCas9	negative selection	7360485
54982089	54982112	5	-	27260156	MHHES1	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.14414926779377119	[330]	[301,503,515,331]	2	hSpCas9	negative selection	7424748
54979424	54979447	5	-	27260156	MHHES1	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.17865769757839645	[295]	[154,297,670,349]	3	hSpCas9	negative selection	7424749
54979341	54979364	5	+	27260156	MHHES1	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	1.0362855090703804	[784]	[1991,1993,1437,1821]	9	hSpCas9	negative selection	7424750
54985339	54985362	5	-	27260156	MEWO	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.3763561213663418	[293]	[446,246,394]	7	hSpCas9	negative selection	7481734
54985440	54985463	5	+	27260156	MEWO	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	-0.04556932072462856	[523]	[483,395,546]	-1	hSpCas9	negative selection	7481735
54982109	54982132	5	+	27260156	MEWO	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.34347181133317406	[831]	[1271,934,810]	7	hSpCas9	negative selection	7481736
54982089	54982112	5	-	27260156	MEWO	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.26254172497798467	[330]	[686,264,223]	5	hSpCas9	negative selection	7545999
54979424	54979447	5	-	27260156	MEWO	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.33779252593492526	[295]	[411,327,321]	7	hSpCas9	negative selection	7546000
54979341	54979364	5	+	27260156	MEWO	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.5656412298901012	[784]	[1426,992,906]	9	hSpCas9	negative selection	7546001
54985339	54985362	5	-	27260156	LNCAPCLONEFGC	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.21153464355688179	[293]	[270,260,313,391]	3	hSpCas9	negative selection	7602985
54985440	54985463	5	+	27260156	LNCAPCLONEFGC	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.18134380902331498	[523]	[475,672,612,393]	3	hSpCas9	negative selection	7602986
54982109	54982132	5	+	27260156	LNCAPCLONEFGC	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.43677101185285383	[831]	[806,1053,1162,1078]	7	hSpCas9	negative selection	7602987
54982089	54982112	5	-	27260156	LNCAPCLONEFGC	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.27136533124226214	[330]	[241,365,446,406]	4	hSpCas9	negative selection	7667250
54979424	54979447	5	-	27260156	LNCAPCLONEFGC	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.0765939578304694	[295]	[296,156,404,297]	1	hSpCas9	negative selection	7667251
54979341	54979364	5	+	27260156	LNCAPCLONEFGC	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.9274362881272218	[784]	[1300,1320,1541,1275]	9	hSpCas9	negative selection	7667252
54985339	54985362	5	-	27260156	PANC0327	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	1.1868283366170975	[293]	[588,786,667,308]	9	hSpCas9	negative selection	7724236
54985440	54985463	5	+	27260156	PANC0327	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.5229749674195638	[523]	[812,449,593,857]	7	hSpCas9	negative selection	7724237
54982109	54982132	5	+	27260156	PANC0327	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.5384013481250638	[831]	[1116,1078,1004,1094]	7	hSpCas9	negative selection	7724238
54982089	54982112	5	-	27260156	PANC0327	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	-0.09485223483132554	[330]	[269,388,203,222]	-1	hSpCas9	negative selection	7788501
54979424	54979447	5	-	27260156	PANC0327	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.5529856134932815	[295]	[284,219,433,616]	7	hSpCas9	negative selection	7788502
54979341	54979364	5	+	27260156	PANC0327	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.6234324705126089	[784]	[1100,875,935,1410]	8	hSpCas9	negative selection	7788503
54985339	54985362	5	-	27260156	NCIH2009	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.34831091253135055	[293]	[642,502,445]	5	hSpCas9	negative selection	7845487
54985440	54985463	5	+	27260156	NCIH2009	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.18071631644514885	[523]	[973,747,795]	2	hSpCas9	negative selection	7845488
54982109	54982132	5	+	27260156	NCIH2009	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.17619668011573375	[831]	[1513,1242,1221]	2	hSpCas9	negative selection	7845489
54982089	54982112	5	-	27260156	NCIH2009	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.05569881056545489	[330]	[500,380,564]	0	hSpCas9	negative selection	7909752
54979424	54979447	5	-	27260156	NCIH2009	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	-0.42406033455711833	[295]	[227,325,353]	-5	hSpCas9	negative selection	7909753
54979341	54979364	5	+	27260156	NCIH2009	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.7811018095093851	[784]	[2001,1563,2113]	9	hSpCas9	negative selection	7909754
54985339	54985362	5	-	27260156	NCIH1373	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.8965214371040827	[293]	[476,538,457,259]	8	hSpCas9	negative selection	7966738
54985440	54985463	5	+	27260156	NCIH1373	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.41235777178347693	[523]	[624,740,710,273]	4	hSpCas9	negative selection	7966739
54982109	54982132	5	+	27260156	NCIH1373	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.23498652921045626	[831]	[1033,1150,1034,302]	2	hSpCas9	negative selection	7966740
54982089	54982112	5	-	27260156	NCIH1373	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.5080334212190925	[330]	[790,475,431,118]	5	hSpCas9	negative selection	8031003
54979424	54979447	5	-	27260156	NCIH1373	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	-0.746227815427424	[295]	[290,138,186,50]	-6	hSpCas9	negative selection	8031004
54979341	54979364	5	+	27260156	NCIH1373	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.9917164398370104	[784]	[2108,1208,2260,393]	8	hSpCas9	negative selection	8031005
54985339	54985362	5	-	27260156	PATU8902	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	1.1521854221418324	[293]	[1362,896,712,676]	9	hSpCas9	negative selection	8087989
54985440	54985463	5	+	27260156	PATU8902	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.9133237227687141	[523]	[969,2166,711,1877]	8	hSpCas9	negative selection	8087990
54982109	54982132	5	+	27260156	PATU8902	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.6100989006502151	[831]	[1542,2174,1514,1914]	6	hSpCas9	negative selection	8087991
54982089	54982112	5	-	27260156	PATU8902	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.8523670300260231	[330]	[931,541,729,1184]	8	hSpCas9	negative selection	8152254
54979424	54979447	5	-	27260156	PATU8902	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.020794656336205253	[295]	[295,541,450,367]	0	hSpCas9	negative selection	8152255
54979341	54979364	5	+	27260156	PATU8902	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	1.1336134663983726	[784]	[1705,2171,2313,3551]	9	hSpCas9	negative selection	8152256
54985339	54985362	5	-	27260156	PANC1	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.7408605560426877	[293]	[649,511,287,268]	9	hSpCas9	negative selection	8209240
54985440	54985463	5	+	27260156	PANC1	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.5894858579127336	[523]	[688,922,384,737]	8	hSpCas9	negative selection	8209241
54982109	54982132	5	+	27260156	PANC1	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.08688325184580814	[831]	[771,777,886,614]	1	hSpCas9	negative selection	8209242
54982089	54982112	5	-	27260156	PANC1	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.30675038704945035	[330]	[378,426,370,254]	5	hSpCas9	negative selection	8273505
54979424	54979447	5	-	27260156	PANC1	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.01081139483665361	[295]	[218,407,243,191]	0	hSpCas9	negative selection	8273506
54979341	54979364	5	+	27260156	PANC1	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.7528938086512793	[784]	[1062,1797,930,907]	9	hSpCas9	negative selection	8273507
54985339	54985362	5	-	27260156	PANC0813	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.4810333339069469	[293]	[368,386,682,478]	7	hSpCas9	negative selection	8330491
54985440	54985463	5	+	27260156	PANC0813	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.02178154969173174	[523]	[634,596,736,535]	0	hSpCas9	negative selection	8330492
54982109	54982132	5	+	27260156	PANC0813	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.1299052578119977	[831]	[1163,1200,962,961]	2	hSpCas9	negative selection	8330493
54982089	54982112	5	-	27260156	PANC0813	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.10991200611110036	[330]	[423,526,367,361]	1	hSpCas9	negative selection	8394756
54979424	54979447	5	-	27260156	PANC0813	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.005261717342735839	[295]	[328,513,275,277]	0	hSpCas9	negative selection	8394757
54979341	54979364	5	+	27260156	PANC0813	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.5393593473792277	[784]	[1507,1213,1351,1301]	8	hSpCas9	negative selection	8394758
54985339	54985362	5	-	27260156	RDES	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.4430686187226627	[293]	[344,422,428,690]	7	hSpCas9	negative selection	8451742
54985440	54985463	5	+	27260156	RDES	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.3737751117162093	[523]	[589,753,864,966]	6	hSpCas9	negative selection	8451743
54982109	54982132	5	+	27260156	RDES	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.23671275919309553	[831]	[863,1123,1200,1386]	4	hSpCas9	negative selection	8451744
54982089	54982112	5	-	27260156	RDES	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.050050596013766824	[330]	[252,391,452,519]	0	hSpCas9	negative selection	8516007
54979424	54979447	5	-	27260156	RDES	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	-0.17102157016984554	[295]	[142,333,346,430]	-3	hSpCas9	negative selection	8516008
54979341	54979364	5	+	27260156	RDES	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.8880617925220968	[784]	[1361,1417,1827,2203]	9	hSpCas9	negative selection	8516009
54985339	54985362	5	-	27260156	PC3	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	-0.08250317559766074	[293]	[200,170,648,238]	-2	hSpCas9	negative selection	8572993
54985440	54985463	5	+	27260156	PC3	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.028619866651783787	[523]	[353,617,660,566]	0	hSpCas9	negative selection	8572994
54982109	54982132	5	+	27260156	PC3	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.35627778200123905	[831]	[570,731,2448,1187]	7	hSpCas9	negative selection	8572995
54982089	54982112	5	-	27260156	PC3	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.09504898690466451	[330]	[154,411,559,423]	2	hSpCas9	negative selection	8637258
54979424	54979447	5	-	27260156	PC3	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.07481771780062474	[295]	[225,249,629,265]	1	hSpCas9	negative selection	8637259
54979341	54979364	5	+	27260156	PC3	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.6143359126047847	[784]	[866,1027,2257,1068]	9	hSpCas9	negative selection	8637260
54985339	54985362	5	-	27260156	PATU8988T	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.5712658958819163	[293]	[387,479,374,453]	8	hSpCas9	negative selection	8694244
54985440	54985463	5	+	27260156	PATU8988T	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.3328309700647994	[523]	[517,736,438,888]	6	hSpCas9	negative selection	8694245
54982109	54982132	5	+	27260156	PATU8988T	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	-0.2363731811168559	[831]	[590,736,696,711]	-4	hSpCas9	negative selection	8694246
54982089	54982112	5	-	27260156	PATU8988T	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.17075696736816254	[330]	[215,513,299,430]	3	hSpCas9	negative selection	8758509
54979424	54979447	5	-	27260156	PATU8988T	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.10125535594578039	[295]	[374,238,338,263]	1	hSpCas9	negative selection	8758510
54979341	54979364	5	+	27260156	PATU8988T	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.7835442036292763	[784]	[969,1092,1899,1224]	9	hSpCas9	negative selection	8758511
54985339	54985362	5	-	27260156	T47D	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.15772621134048492	[293]	[413,339,410,365]	3	hSpCas9	negative selection	8815495
54985440	54985463	5	+	27260156	T47D	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.20727490933105952	[523]	[696,672,703,748]	4	hSpCas9	negative selection	8815496
54982109	54982132	5	+	27260156	T47D	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.28088100403249916	[831]	[1143,1034,1227,1318]	6	hSpCas9	negative selection	8815497
54982089	54982112	5	-	27260156	T47D	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.25715434948873667	[330]	[503,465,447,423]	5	hSpCas9	negative selection	8879760
54979424	54979447	5	-	27260156	T47D	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.12049206710699867	[295]	[356,337,443,361]	2	hSpCas9	negative selection	8879761
54979341	54979364	5	+	27260156	T47D	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.7700501908241628	[784]	[1686,1405,1556,1602]	9	hSpCas9	negative selection	8879762
54985339	54985362	5	-	27260156	SU8686	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.35442506131611257	[293]	[393,304,433,360]	6	hSpCas9	negative selection	8936746
54985440	54985463	5	+	27260156	SU8686	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	-0.008890539851232171	[523]	[470,556,499,535]	0	hSpCas9	negative selection	8936747
54982109	54982132	5	+	27260156	SU8686	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.12216225173425443	[831]	[910,786,787,1148]	2	hSpCas9	negative selection	8936748
54982089	54982112	5	-	27260156	SU8686	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	-0.051844941043733606	[330]	[233,251,343,478]	-1	hSpCas9	negative selection	9001011
54979424	54979447	5	-	27260156	SU8686	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.17647856270895657	[295]	[229,384,328,394]	3	hSpCas9	negative selection	9001012
54979341	54979364	5	+	27260156	SU8686	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.8066978013055597	[784]	[1316,1214,1392,1568]	9	hSpCas9	negative selection	9001013
54985339	54985362	5	-	27260156	SKES1	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.08170865094333313	[293]	[387,288,300,272]	1	hSpCas9	negative selection	9057997
54985440	54985463	5	+	27260156	SKES1	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.2962185063276806	[523]	[646,717,663,551]	6	hSpCas9	negative selection	9057998
54982109	54982132	5	+	27260156	SKES1	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.33268888789333095	[831]	[900,1374,1008,919]	7	hSpCas9	negative selection	9057999
54982089	54982112	5	-	27260156	SKES1	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	-0.08425705765535774	[330]	[417,463,202,204]	-2	hSpCas9	negative selection	9122262
54979424	54979447	5	-	27260156	SKES1	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	-0.15857799760350577	[295]	[254,275,296,230]	-3	hSpCas9	negative selection	9122263
54979341	54979364	5	+	27260156	SKES1	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.7448906033313132	[784]	[1100,1591,1291,1260]	9	hSpCas9	negative selection	9122264
54985339	54985362	5	-	27260156	TOV112D	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.0059108310031671385	[293]	[288,261,314,306]	0	hSpCas9	negative selection	9179248
54985440	54985463	5	+	27260156	TOV112D	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.44556563778277175	[523]	[963,702,646,565]	8	hSpCas9	negative selection	9179249
54982109	54982132	5	+	27260156	TOV112D	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.18081845171280242	[831]	[1086,1146,823,784]	3	hSpCas9	negative selection	9179250
54982089	54982112	5	-	27260156	TOV112D	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.17555196989457694	[330]	[316,397,263,514]	3	hSpCas9	negative selection	9243513
54979424	54979447	5	-	27260156	TOV112D	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.00664576026065633	[295]	[321,425,272,205]	0	hSpCas9	negative selection	9243514
54979341	54979364	5	+	27260156	TOV112D	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.7771207742825632	[784]	[1352,1950,1276,965]	9	hSpCas9	negative selection	9243515
54985339	54985362	5	-	27260156	TC71	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.21350567359840605	[293]	[290,339,364,473]	5	hSpCas9	negative selection	9300499
54985440	54985463	5	+	27260156	TC71	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.10381277073218526	[523]	[578,762,544,524]	2	hSpCas9	negative selection	9300500
54982109	54982132	5	+	27260156	TC71	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.2911804935283131	[831]	[996,1109,1044,1224]	7	hSpCas9	negative selection	9300501
54982089	54982112	5	-	27260156	TC71	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.057871023473525796	[330]	[322,397,364,393]	1	hSpCas9	negative selection	9364764
54979424	54979447	5	-	27260156	TC71	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.0015697083393730882	[295]	[279,330,287,376]	0	hSpCas9	negative selection	9364765
54979341	54979364	5	+	27260156	TC71	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.7982772167194827	[784]	[1407,1530,1410,1508]	9	hSpCas9	negative selection	9364766
54985339	54985362	5	-	27260156	TC32	viability	TGCTGCCGAGTGTGCGCTGCAGG	ESM1	ENSG00000164283	0.4029527040269177	[293]	[452,180,462,421]	7	hSpCas9	negative selection	9421750
54985440	54985463	5	+	27260156	TC32	viability	CACCGCATAATTATTGCTCCAGG	ESM1	ENSG00000164283	0.46154643252933886	[523]	[796,478,779,692]	7	hSpCas9	negative selection	9421751
54982109	54982132	5	+	27260156	TC32	viability	CTCTCTGCAATCCATCCCGAAGG	ESM1	ENSG00000164283	0.18483204637902584	[831]	[837,721,1259,809]	3	hSpCas9	negative selection	9421752
54982089	54982112	5	-	27260156	TC32	viability	GAGACCTGCAACTGCCAGTCAGG	ESM1	ENSG00000164283	0.3337694663373537	[330]	[365,288,464,484]	6	hSpCas9	negative selection	9486015
54979424	54979447	5	-	27260156	TC32	viability	TCTACTTTCAGAGCATGACATGG	ESM1	ENSG00000164283	0.036492548212144316	[295]	[223,179,412,383]	0	hSpCas9	negative selection	9486016
54979341	54979364	5	+	27260156	TC32	viability	ATTTAACCATTTCCTCATTACGG	ESM1	ENSG00000164283	0.7777562898960664	[784]	[1110,953,1770,1379]	9	hSpCas9	negative selection	9486017
54979318	54979341	5	+	27869803	HPAFII	viability after 27 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.8294310194471244	[357]	[352,318,NaN]	6	hSpCas9	negative selection	9592107
54979350	54979373	5	+	27869803	HPAFII	viability after 27 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	0.927580454375704	[0]	[0,0,NaN]	7	hSpCas9	negative selection	9592108
54985376	54985399	5	+	27869803	HPAFII	viability after 27 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.26410592547602385	[235]	[142,153,NaN]	2	hSpCas9	negative selection	9592109
54985439	54985462	5	-	27869803	HPAFII	viability after 27 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.019725311850578464	[825]	[405,446,NaN]	0	hSpCas9	negative selection	9592110
54985443	54985466	5	+	27869803	HPAFII	viability after 27 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	1.7055890601553583	[326]	[725,422,NaN]	9	hSpCas9	negative selection	9592111
54979318	54979341	5	+	27869803	HPAFII	viability after 15 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.6762919136331154	[357]	[575,638,NaN]	7	hSpCas9	negative selection	9674556
54979350	54979373	5	+	27869803	HPAFII	viability after 15 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	-0.10397428375416773	[0]	[0,0,NaN]	-1	hSpCas9	negative selection	9674557
54985376	54985399	5	+	27869803	HPAFII	viability after 15 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.8269316034562518	[235]	[563,378,NaN]	8	hSpCas9	negative selection	9674558
54985439	54985462	5	-	27869803	HPAFII	viability after 15 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.3166323171811032	[825]	[816,647,NaN]	-4	hSpCas9	negative selection	9674559
54985443	54985466	5	+	27869803	HPAFII	viability after 15 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	0.9372203829455414	[326]	[778,606,NaN]	8	hSpCas9	negative selection	9674560
54979318	54979341	5	+	27869803	ASPC1	viability after 36 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.3537711657130338	[1104]	[511,413,536]	3	hSpCas9	negative selection	9757005
54979350	54979373	5	+	27869803	ASPC1	viability after 36 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	0.8165068836442197	[214]	[10,44,284]	7	hSpCas9	negative selection	9757006
54985376	54985399	5	+	27869803	ASPC1	viability after 36 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.18914278611052365	[833]	[623,358,101]	1	hSpCas9	negative selection	9757007
54985439	54985462	5	-	27869803	ASPC1	viability after 36 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.44016045780683055	[1601]	[572,691,933]	4	hSpCas9	negative selection	9757008
54985443	54985466	5	+	27869803	ASPC1	viability after 36 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	0.09348981217248375	[971]	[494,308,306]	0	hSpCas9	negative selection	9757009
54979318	54979341	5	+	27869803	PATU8988S	viability after 35 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	0.2905993110631051	[840]	[324,503,NaN]	3	hSpCas9	negative selection	9839454
54979350	54979373	5	+	27869803	PATU8988S	viability after 35 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	-0.03008999828252601	[170]	[44,89,NaN]	0	hSpCas9	negative selection	9839455
54985376	54985399	5	+	27869803	PATU8988S	viability after 35 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	-0.05541087129339428	[818]	[283,350,NaN]	0	hSpCas9	negative selection	9839456
54985439	54985462	5	-	27869803	PATU8988S	viability after 35 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.05388789445281539	[1662]	[591,798,NaN]	0	hSpCas9	negative selection	9839457
54985443	54985466	5	+	27869803	PATU8988S	viability after 35 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	0.1727619270684273	[893]	[345,465,NaN]	2	hSpCas9	negative selection	9839458
54979318	54979341	5	+	27869803	PATU8988S	viability after 31 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	-0.1959666446112192	[840]	[246,350,NaN]	-2	hSpCas9	negative selection	9921903
54979350	54979373	5	+	27869803	PATU8988S	viability after 31 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	-0.9263758124076982	[170]	[23,50,NaN]	-7	hSpCas9	negative selection	9921904
54985376	54985399	5	+	27869803	PATU8988S	viability after 31 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.1662607226555617	[818]	[270,487,NaN]	2	hSpCas9	negative selection	9921905
54985439	54985462	5	-	27869803	PATU8988S	viability after 31 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.12359229408562666	[1662]	[633,834,NaN]	1	hSpCas9	negative selection	9921906
54985443	54985466	5	+	27869803	PATU8988S	viability after 31 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	0.06590289525287363	[893]	[267,506,NaN]	0	hSpCas9	negative selection	9921907
54979318	54979341	5	+	27869803	HPAFII	viability after 35 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	1.3852344438518098	[357]	[241,733,NaN]	8	hSpCas9	negative selection	10004352
54979350	54979373	5	+	27869803	HPAFII	viability after 35 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	0.9820885529966752	[0]	[0,0,NaN]	6	hSpCas9	negative selection	10004353
54985376	54985399	5	+	27869803	HPAFII	viability after 35 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.47255996633091446	[235]	[74,267,NaN]	3	hSpCas9	negative selection	10004354
54985439	54985462	5	-	27869803	HPAFII	viability after 35 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.13505568964274084	[825]	[432,321,NaN]	-1	hSpCas9	negative selection	10004355
54985443	54985466	5	+	27869803	HPAFII	viability after 35 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	2.2537263492106	[326]	[1193,333,NaN]	9	hSpCas9	negative selection	10004356
54979318	54979341	5	+	27869803	HPAFII	viability after 31 days	AATCACAGCCGGGATCAGCGTGG	ESM1	ENSG00000164283	1.0795159834290167	[357]	[303,555,NaN]	7	hSpCas9	negative selection	10086801
54979350	54979373	5	+	27869803	HPAFII	viability after 31 days	TTTCCTCATTACGGGAGACCCGG	ESM1	ENSG00000164283	0.8333711996752582	[0]	[0,0,NaN]	6	hSpCas9	negative selection	10086802
54985376	54985399	5	+	27869803	HPAFII	viability after 31 days	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.6832105669596631	[235]	[115,317,NaN]	5	hSpCas9	negative selection	10086803
54985439	54985462	5	-	27869803	HPAFII	viability after 31 days	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.0915109788163595	[825]	[480,507,NaN]	0	hSpCas9	negative selection	10086804
54985443	54985466	5	+	27869803	HPAFII	viability after 31 days	CGCATAATTATTGCTCCAGGCGG	ESM1	ENSG00000164283	2.039915564617922	[326]	[1003,482,NaN]	9	hSpCas9	negative selection	10086805
54985439	54985462	5	-	28162770	P31FUJ	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.8794072991716463	[135]	[293]	8	hSpCas9	negative selection	10151420
54985459	54985482	5	+	28162770	P31FUJ	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	0.39309056036165957	[277]	[428]	4	hSpCas9	negative selection	10151421
54985285	54985308	5	-	28162770	P31FUJ	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.8006725001367094	[212]	[435]	8	hSpCas9	negative selection	10151422
54985335	54985358	5	-	28162770	P31FUJ	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	0.21198263825851726	[71]	[97]	2	hSpCas9	negative selection	10151423
54985261	54985284	5	+	28162770	P31FUJ	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	1.032436472346145	[108]	[261]	9	hSpCas9	negative selection	10151424
54985216	54985239	5	-	28162770	P31FUJ	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	0.14371743365455303	[445]	[578]	1	hSpCas9	negative selection	10151425
54985473	54985496	5	+	28162770	P31FUJ	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	0.6293885837233257	[235]	[428]	7	hSpCas9	negative selection	10151426
54985383	54985406	5	-	28162770	P31FUJ	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	0.15567708338158986	[232]	[304]	1	hSpCas9	negative selection	10151427
54985376	54985399	5	+	28162770	P31FUJ	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	-0.12386783286121458	[203]	[219]	-1	hSpCas9	negative selection	10151428
54985301	54985324	5	-	28162770	P31FUJ	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.4842245426984968	[611]	[1005]	5	hSpCas9	negative selection	10151429
54985439	54985462	5	-	28162770	TF1	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10320786
54985459	54985482	5	+	28162770	TF1	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	NaN	[NaN]	[233]	1	hSpCas9	negative selection	10320787
54985285	54985308	5	-	28162770	TF1	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	NaN	[NaN]	[208]	1	hSpCas9	negative selection	10320788
54985335	54985358	5	-	28162770	TF1	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10320789
54985261	54985284	5	+	28162770	TF1	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	NaN	[NaN]	[70]	1	hSpCas9	negative selection	10320790
54985216	54985239	5	-	28162770	TF1	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	NaN	[NaN]	[415]	1	hSpCas9	negative selection	10320791
54985473	54985496	5	+	28162770	TF1	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	NaN	[NaN]	[220]	1	hSpCas9	negative selection	10320792
54985383	54985406	5	-	28162770	TF1	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	NaN	[NaN]	[366]	1	hSpCas9	negative selection	10320793
54985376	54985399	5	+	28162770	TF1	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10320794
54985301	54985324	5	-	28162770	TF1	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	NaN	[NaN]	[602]	1	hSpCas9	negative selection	10320795
54985439	54985462	5	-	28162770	SKM1	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-1.0443941193584534	[48]	[41]	-6	hSpCas9	negative selection	10490152
54985459	54985482	5	+	28162770	SKM1	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	0.05600777759938408	[73]	[135]	0	hSpCas9	negative selection	10490153
54985285	54985308	5	-	28162770	SKM1	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	-0.48192625642438375	[78]	[99]	-4	hSpCas9	negative selection	10490154
54985335	54985358	5	-	28162770	SKM1	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	-0.7776075786635521	[31]	[32]	-5	hSpCas9	negative selection	10490155
54985261	54985284	5	+	28162770	SKM1	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	-0.5945912019189329	[40]	[47]	-5	hSpCas9	negative selection	10490156
54985216	54985239	5	-	28162770	SKM1	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	0.6180124667880511	[135]	[368]	6	hSpCas9	negative selection	10490157
54985473	54985496	5	+	28162770	SKM1	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	0.44103270781178816	[44]	[107]	4	hSpCas9	negative selection	10490158
54985383	54985406	5	-	28162770	SKM1	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	1.7828603601368553	[35]	[218]	9	hSpCas9	negative selection	10490159
54985376	54985399	5	+	28162770	SKM1	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.8047809783937778	[33]	[104]	7	hSpCas9	negative selection	10490160
54985301	54985324	5	-	28162770	SKM1	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.7109385903508685	[159]	[462]	6	hSpCas9	negative selection	10490161
54985439	54985462	5	-	28162770	SKM1	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-1.0443941193584534	[48]	[41]	-6	hSpCas9	negative selection	10659518
54985459	54985482	5	+	28162770	SKM1	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	0.05600777759938408	[73]	[135]	0	hSpCas9	negative selection	10659519
54985285	54985308	5	-	28162770	SKM1	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	-0.48192625642438375	[78]	[99]	-4	hSpCas9	negative selection	10659520
54985335	54985358	5	-	28162770	SKM1	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	-0.7776075786635521	[31]	[32]	-5	hSpCas9	negative selection	10659521
54985261	54985284	5	+	28162770	SKM1	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	-0.5945912019189329	[40]	[47]	-5	hSpCas9	negative selection	10659522
54985216	54985239	5	-	28162770	SKM1	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	0.6180124667880511	[135]	[368]	6	hSpCas9	negative selection	10659523
54985473	54985496	5	+	28162770	SKM1	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	0.44103270781178816	[44]	[107]	4	hSpCas9	negative selection	10659524
54985383	54985406	5	-	28162770	SKM1	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	1.7828603601368553	[35]	[218]	9	hSpCas9	negative selection	10659525
54985376	54985399	5	+	28162770	SKM1	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.8047809783937778	[33]	[104]	7	hSpCas9	negative selection	10659526
54985301	54985324	5	-	28162770	SKM1	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.7109385903508685	[159]	[462]	6	hSpCas9	negative selection	10659527
54985439	54985462	5	-	28162770	PL21	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.8929697899021614	[127]	[29]	-6	hSpCas9	negative selection	10828884
54985459	54985482	5	+	28162770	PL21	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	0.47952201441059755	[233]	[141]	4	hSpCas9	negative selection	10828885
54985285	54985308	5	-	28162770	PL21	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.24353221000270092	[261]	[134]	2	hSpCas9	negative selection	10828886
54985335	54985358	5	-	28162770	PL21	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	-0.31770869037329885	[62]	[21]	-2	hSpCas9	negative selection	10828887
54985261	54985284	5	+	28162770	PL21	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	0.3346817378681478	[132]	[72]	3	hSpCas9	negative selection	10828888
54985216	54985239	5	-	28162770	PL21	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	0.5011803429028587	[486]	[299]	4	hSpCas9	negative selection	10828889
54985473	54985496	5	+	28162770	PL21	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	-0.6588165040554965	[184]	[50]	-4	hSpCas9	negative selection	10828890
54985383	54985406	5	-	28162770	PL21	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	1.117677454297347	[161]	[152]	8	hSpCas9	negative selection	10828891
54985376	54985399	5	+	28162770	PL21	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.7809143182470427	[114]	[85]	6	hSpCas9	negative selection	10828892
54985301	54985324	5	-	28162770	PL21	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.6365056232086757	[469]	[317]	5	hSpCas9	negative selection	10828893
54985439	54985462	5	-	28162770	P31FUJ	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.8794072991716463	[135]	[293]	8	hSpCas9	negative selection	10998250
54985459	54985482	5	+	28162770	P31FUJ	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	0.39309056036165957	[277]	[428]	4	hSpCas9	negative selection	10998251
54985285	54985308	5	-	28162770	P31FUJ	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.8006725001367094	[212]	[435]	8	hSpCas9	negative selection	10998252
54985335	54985358	5	-	28162770	P31FUJ	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	0.21198263825851726	[71]	[97]	2	hSpCas9	negative selection	10998253
54985261	54985284	5	+	28162770	P31FUJ	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	1.032436472346145	[108]	[261]	9	hSpCas9	negative selection	10998254
54985216	54985239	5	-	28162770	P31FUJ	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	0.14371743365455303	[445]	[578]	1	hSpCas9	negative selection	10998255
54985473	54985496	5	+	28162770	P31FUJ	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	0.6293885837233257	[235]	[428]	7	hSpCas9	negative selection	10998256
54985383	54985406	5	-	28162770	P31FUJ	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	0.15567708338158986	[232]	[304]	1	hSpCas9	negative selection	10998257
54985376	54985399	5	+	28162770	P31FUJ	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	-0.12386783286121458	[203]	[219]	-1	hSpCas9	negative selection	10998258
54985301	54985324	5	-	28162770	P31FUJ	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.4842245426984968	[611]	[1005]	5	hSpCas9	negative selection	10998259
54985439	54985462	5	-	28162770	OCIAML5	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.647693607320274	[92]	[262]	5	hSpCas9	negative selection	11167616
54985459	54985482	5	+	28162770	OCIAML5	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	1.2412371489754028	[115]	[494]	9	hSpCas9	negative selection	11167617
54985285	54985308	5	-	28162770	OCIAML5	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	1.0483977555850887	[149]	[559]	8	hSpCas9	negative selection	11167618
54985335	54985358	5	-	28162770	OCIAML5	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	-0.8938867465586239	[69]	[67]	-5	hSpCas9	negative selection	11167619
54985261	54985284	5	+	28162770	OCIAML5	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	-1.1497471195046822	[58]	[47]	-6	hSpCas9	negative selection	11167620
54985216	54985239	5	-	28162770	OCIAML5	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	0.9674709734596771	[218]	[772]	8	hSpCas9	negative selection	11167621
54985473	54985496	5	+	28162770	OCIAML5	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	0.14793342913600308	[106]	[213]	1	hSpCas9	negative selection	11167622
54985383	54985406	5	-	28162770	OCIAML5	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	0.5477364147196865	[118]	[313]	5	hSpCas9	negative selection	11167623
54985376	54985399	5	+	28162770	OCIAML5	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	-0.5060707160148046	[106]	[135]	-3	hSpCas9	negative selection	11167624
54985301	54985324	5	-	28162770	OCIAML5	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.33506474598465474	[425]	[969]	3	hSpCas9	negative selection	11167625
54985439	54985462	5	-	28162770	EOL1	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.5334418728928563	[249]	[90]	-4	hSpCas9	negative selection	11336982
54985459	54985482	5	+	28162770	EOL1	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	0.4229410173448582	[268]	[189]	4	hSpCas9	negative selection	11336983
54985285	54985308	5	-	28162770	EOL1	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.5264634055728882	[422]	[320]	5	hSpCas9	negative selection	11336984
54985335	54985358	5	-	28162770	EOL1	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	-0.3973803233168276	[169]	[67]	-3	hSpCas9	negative selection	11336985
54985261	54985284	5	+	28162770	EOL1	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	0.3638328170960557	[235]	[159]	3	hSpCas9	negative selection	11336986
54985216	54985239	5	-	28162770	EOL1	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	0.004401079259749308	[860]	[454]	0	hSpCas9	negative selection	11336987
54985473	54985496	5	+	28162770	EOL1	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	-0.7881702763489943	[235]	[71]	-5	hSpCas9	negative selection	11336988
54985383	54985406	5	-	28162770	EOL1	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	0.5933418630951613	[194]	[154]	5	hSpCas9	negative selection	11336989
54985376	54985399	5	+	28162770	EOL1	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	-1.2542553812182304	[162]	[35]	-7	hSpCas9	negative selection	11336990
54985301	54985324	5	-	28162770	EOL1	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.34858526910033016	[798]	[535]	3	hSpCas9	negative selection	11336991
54985439	54985462	5	-	28162770	MOLM13	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	1.4929803625074092	[170]	[347]	9	hSpCas9	negative selection	11506348
54985459	54985482	5	+	28162770	MOLM13	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	0.7468653312473943	[299]	[363]	5	hSpCas9	negative selection	11506349
54985285	54985308	5	-	28162770	MOLM13	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	1.1857461527630802	[303]	[499]	8	hSpCas9	negative selection	11506350
54985335	54985358	5	-	28162770	MOLM13	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	-0.8988929491270442	[146]	[56]	-5	hSpCas9	negative selection	11506351
54985261	54985284	5	+	28162770	MOLM13	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	1.1380000009545337	[158]	[252]	8	hSpCas9	negative selection	11506352
54985216	54985239	5	-	28162770	MOLM13	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	0.2469339075788055	[668]	[573]	1	hSpCas9	negative selection	11506353
54985473	54985496	5	+	28162770	MOLM13	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	-0.2756190584883994	[220]	[131]	-2	hSpCas9	negative selection	11506354
54985383	54985406	5	-	28162770	MOLM13	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	0.3457422722587882	[270]	[248]	2	hSpCas9	negative selection	11506355
54985376	54985399	5	+	28162770	MOLM13	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	1.0468280946379651	[159]	[238]	7	hSpCas9	negative selection	11506356
54985301	54985324	5	-	28162770	MOLM13	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.48114040504243505	[866]	[874]	3	hSpCas9	negative selection	11506357
54985439	54985462	5	-	28162770	HEL	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	1.1998671245247876	[156]	[230]	9	hSpCas9	negative selection	11675714
54985459	54985482	5	+	28162770	HEL	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	0.9495234406271774	[248]	[307]	8	hSpCas9	negative selection	11675715
54985285	54985308	5	-	28162770	HEL	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	1.10786156271551	[275]	[380]	8	hSpCas9	negative selection	11675716
54985335	54985358	5	-	28162770	HEL	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	-1.1696341648238717	[143]	[40]	-6	hSpCas9	negative selection	11675717
54985261	54985284	5	+	28162770	HEL	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	0.2743514260203344	[141]	[109]	2	hSpCas9	negative selection	11675718
54985216	54985239	5	-	28162770	HEL	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	0.5520405217086197	[557]	[523]	4	hSpCas9	negative selection	11675719
54985473	54985496	5	+	28162770	HEL	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	-0.23953920912654836	[246]	[133]	-2	hSpCas9	negative selection	11675720
54985383	54985406	5	-	28162770	HEL	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	0.3578577238683145	[172]	[141]	3	hSpCas9	negative selection	11675721
54985376	54985399	5	+	28162770	HEL	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	-0.27373781243735973	[150]	[79]	-2	hSpCas9	negative selection	11675722
54985301	54985324	5	-	28162770	HEL	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.47576714794739217	[731]	[651]	4	hSpCas9	negative selection	11675723
54985439	54985462	5	-	28162770	MV411	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.08598618294241667	[125]	[99]	0	hSpCas9	negative selection	11845080
54985459	54985482	5	+	28162770	MV411	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	1.0094941259118118	[170]	[289]	8	hSpCas9	negative selection	11845081
54985285	54985308	5	-	28162770	MV411	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	0.18636197403100696	[192]	[184]	1	hSpCas9	negative selection	11845082
54985335	54985358	5	-	28162770	MV411	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	-0.5599173712748289	[76]	[43]	-4	hSpCas9	negative selection	11845083
54985261	54985284	5	+	28162770	MV411	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	-1.0744905441045867	[104]	[41]	-6	hSpCas9	negative selection	11845084
54985216	54985239	5	-	28162770	MV411	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	-0.1332243688950534	[469]	[360]	-1	hSpCas9	negative selection	11845085
54985473	54985496	5	+	28162770	MV411	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	0.0991148038256741	[173]	[156]	0	hSpCas9	negative selection	11845086
54985383	54985406	5	-	28162770	MV411	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	0.8043077444745785	[120]	[177]	7	hSpCas9	negative selection	11845087
54985376	54985399	5	+	28162770	MV411	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.19085402241640775	[129]	[124]	1	hSpCas9	negative selection	11845088
54985301	54985324	5	-	28162770	MV411	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.6560200279243196	[503]	[668]	6	hSpCas9	negative selection	11845089
54985439	54985462	5	-	28162770	MONOMAC1	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.2986583155645152	[99]	[140]	3	hSpCas9	negative selection	12014446
54985459	54985482	5	+	28162770	MONOMAC1	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	0.7903631161608128	[114]	[227]	7	hSpCas9	negative selection	12014447
54985285	54985308	5	-	28162770	MONOMAC1	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	-0.020487455305989277	[168]	[190]	0	hSpCas9	negative selection	12014448
54985335	54985358	5	-	28162770	MONOMAC1	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	-0.7463754380499885	[59]	[40]	-6	hSpCas9	negative selection	12014449
54985261	54985284	5	+	28162770	MONOMAC1	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	0.4968600252147665	[67]	[109]	5	hSpCas9	negative selection	12014450
54985216	54985239	5	-	28162770	MONOMAC1	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	-0.14456942716541832	[323]	[335]	-1	hSpCas9	negative selection	12014451
54985473	54985496	5	+	28162770	MONOMAC1	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	-0.9879412483365637	[108]	[62]	-7	hSpCas9	negative selection	12014452
54985383	54985406	5	-	28162770	MONOMAC1	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	0.5876254891379488	[118]	[204]	6	hSpCas9	negative selection	12014453
54985376	54985399	5	+	28162770	MONOMAC1	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.5254291774115375	[79]	[131]	5	hSpCas9	negative selection	12014454
54985301	54985324	5	-	28162770	MONOMAC1	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.6656893394116623	[313]	[570]	6	hSpCas9	negative selection	12014455
54985439	54985462	5	-	28162770	OCIAML2	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	0.344630294900789	[25]	[182]	3	hSpCas9	negative selection	12183812
54985459	54985482	5	+	28162770	OCIAML2	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	1.143064394022311	[28]	[354]	9	hSpCas9	negative selection	12183813
54985285	54985308	5	-	28162770	OCIAML2	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	1.087697548975528	[40]	[482]	9	hSpCas9	negative selection	12183814
54985335	54985358	5	-	28162770	OCIAML2	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	0.4742286205653778	[19]	[153]	4	hSpCas9	negative selection	12183815
54985261	54985284	5	+	28162770	OCIAML2	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	0.10384030166135272	[22]	[136]	1	hSpCas9	negative selection	12183816
54985216	54985239	5	-	28162770	OCIAML2	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	0.27025081892742797	[91]	[614]	2	hSpCas9	negative selection	12183817
54985473	54985496	5	+	28162770	OCIAML2	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	0.4854268271702417	[24]	[193]	5	hSpCas9	negative selection	12183818
54985383	54985406	5	-	28162770	OCIAML2	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	1.6950705903384258	[18]	[340]	9	hSpCas9	negative selection	12183819
54985376	54985399	5	+	28162770	OCIAML2	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	0.6420703075072012	[19]	[172]	6	hSpCas9	negative selection	12183820
54985301	54985324	5	-	28162770	OCIAML2	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.501227210412134	[109]	[862]	5	hSpCas9	negative selection	12183821
54985439	54985462	5	-	28162770	OCIAML3	viability	CTGGAGCAATAATTATGCGGTGG	ESM1	ENSG00000164283	-0.13103566398161737	[36]	[101]	-1	hSpCas9	negative selection	12353178
54985459	54985482	5	+	28162770	OCIAML3	viability	CAGGCGGCCACCAGGTGTGCAGG	ESM1	ENSG00000164283	0.4826136412787493	[54]	[231]	4	hSpCas9	negative selection	12353179
54985285	54985308	5	-	28162770	OCIAML3	viability	GGCATGGATGGCATGAAGTGTGG	ESM1	ENSG00000164283	-0.4684767582403042	[54]	[119]	-4	hSpCas9	negative selection	12353180
54985335	54985358	5	-	28162770	OCIAML3	viability	GCCGAGTGTGCGCTGCAGGGCGG	ESM1	ENSG00000164283	-1.1997287012121167	[34]	[45]	-7	hSpCas9	negative selection	12353181
54985261	54985284	5	+	28162770	OCIAML3	viability	GAAGGCTGACACCTCAGCCCCGG	ESM1	ENSG00000164283	-2.0858607366538378	[44]	[31]	-8	hSpCas9	negative selection	12353182
54985216	54985239	5	-	28162770	OCIAML3	viability	GAAGAGTTTGGTATCTGCAAAGG	ESM1	ENSG00000164283	0.5873221243903985	[111]	[507]	5	hSpCas9	negative selection	12353183
54985473	54985496	5	+	28162770	OCIAML3	viability	GTGTGCAGGCACGAGGAGCGTGG	ESM1	ENSG00000164283	0.4059923596758368	[49]	[199]	4	hSpCas9	negative selection	12353184
54985383	54985406	5	-	28162770	OCIAML3	viability	AAAGCAGCCCGCGCTGCAAGAGG	ESM1	ENSG00000164283	0.446406628121745	[43]	[180]	4	hSpCas9	negative selection	12353185
54985376	54985399	5	+	28162770	OCIAML3	viability	GCACTGTCCTCTTGCAGCGCGGG	ESM1	ENSG00000164283	-0.8909893780812946	[42]	[69]	-6	hSpCas9	negative selection	12353186
54985301	54985324	5	-	28162770	OCIAML3	viability	CTACCGCACAGTCTCAGGCATGG	ESM1	ENSG00000164283	0.20768964687151503	[145]	[508]	2	hSpCas9	negative selection	12353187