Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 169792
• Symbol: GLIS3
• Description: GLIS family zinc finger 3

DataSource: http://genomecrispr.dkfz.de/#!/results/GLIS3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
4118758	4118781	9	+	26472758	Jiyoye	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	0.7482122993409404	[119]	[151]	5	hSpCas9	negative selection	63828
3829408	3829431	9	+	26472758	Jiyoye	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	-1.2652499604656224	[50]	[15]	-7	hSpCas9	negative selection	63829
3879453	3879476	9	+	26472758	Jiyoye	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-0.29736873496795524	[219]	[134]	-2	hSpCas9	negative selection	63830
4118600	4118623	9	+	26472758	Jiyoye	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	0.32917286950460034	[37]	[35]	2	hSpCas9	negative selection	63831
4118241	4118264	9	-	26472758	Jiyoye	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	-0.3010584941170166	[231]	[141]	-2	hSpCas9	negative selection	63832
3937058	3937081	9	+	26472758	Jiyoye	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	2.1687266139503527	[63]	[216]	9	hSpCas9	negative selection	63833
3937043	3937066	9	-	26472758	Jiyoye	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	2.0066374519221446	[32]	[99]	8	hSpCas9	negative selection	63834
3879511	3879534	9	+	26472758	Jiyoye	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	0.17271012786885054	[159]	[135]	1	hSpCas9	negative selection	63835
3856125	3856148	9	+	26472758	Jiyoye	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	-0.0078621177729703	[247]	[185]	0	hSpCas9	negative selection	63836
4118758	4118781	9	+	26472758	KBM7	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	-0.37232364532398116	[696,653]	[372,131]	-3	hSpCas9	negative selection	254946
3829408	3829431	9	+	26472758	KBM7	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	-2.0655967437038982	[61,95]	[6,10]	-8	hSpCas9	negative selection	254947
3879453	3879476	9	+	26472758	KBM7	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-0.4683457047783234	[772,710]	[302,206]	-4	hSpCas9	negative selection	254948
4118600	4118623	9	+	26472758	KBM7	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	0.12009739789003904	[99,106]	[65,41]	1	hSpCas9	negative selection	254949
4118241	4118264	9	-	26472758	KBM7	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	0.15982155593436476	[951,487]	[488,258]	1	hSpCas9	negative selection	254950
3937058	3937081	9	+	26472758	KBM7	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	0.1834566572373112	[831,646]	[396,386]	1	hSpCas9	negative selection	254951
3937043	3937066	9	-	26472758	KBM7	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	0.808686802581865	[499,526]	[442,410]	8	hSpCas9	negative selection	254952
3879511	3879534	9	+	26472758	KBM7	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	0.49760161326570396	[1243,975]	[771,694]	5	hSpCas9	negative selection	254953
3856125	3856148	9	+	26472758	KBM7	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	0.5773875071699073	[722,413]	[517,274]	6	hSpCas9	negative selection	254954
4118758	4118781	9	+	26472758	Raji	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	-0.5469270120382914	[276]	[43]	-4	hSpCas9	negative selection	446064
3829408	3829431	9	+	26472758	Raji	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	3.2329144174574584	[10]	[23]	9	hSpCas9	negative selection	446065
3879453	3879476	9	+	26472758	Raji	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-0.4148432099995942	[269]	[46]	-3	hSpCas9	negative selection	446066
4118600	4118623	9	+	26472758	Raji	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	1.5224210346524436	[32]	[21]	9	hSpCas9	negative selection	446067
4118241	4118264	9	-	26472758	Raji	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	0.47351143417149666	[359]	[115]	4	hSpCas9	negative selection	446068
3937058	3937081	9	+	26472758	Raji	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	0.5505720749665926	[405]	[137]	5	hSpCas9	negative selection	446069
3937043	3937066	9	-	26472758	Raji	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	0.30320286111113914	[226]	[64]	3	hSpCas9	negative selection	446070
3879511	3879534	9	+	26472758	Raji	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	-0.1786249852588202	[594]	[121]	-1	hSpCas9	negative selection	446071
3856125	3856148	9	+	26472758	Raji	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	0.16526445145409951	[341]	[88]	1	hSpCas9	negative selection	446072
4118758	4118781	9	+	26472758	K562	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	0.7044546164867727	[433]	[596]	6	hSpCas9	negative selection	637182
3829408	3829431	9	+	26472758	K562	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	0.15826208391673235	[68]	[64]	1	hSpCas9	negative selection	637183
3879453	3879476	9	+	26472758	K562	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	0.24982208619578034	[532]	[534]	2	hSpCas9	negative selection	637184
4118600	4118623	9	+	26472758	K562	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	-0.7880027500259308	[89]	[43]	-5	hSpCas9	negative selection	637185
4118241	4118264	9	-	26472758	K562	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	-0.7880027500259306	[539]	[263]	-5	hSpCas9	negative selection	637186
3937058	3937081	9	+	26472758	K562	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	0.2887410586517415	[608]	[627]	2	hSpCas9	negative selection	637187
3937043	3937066	9	-	26472758	K562	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	1.0572591888077807	[299]	[526]	8	hSpCas9	negative selection	637188
3879511	3879534	9	+	26472758	K562	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	1.195732948314738	[888]	[1718]	8	hSpCas9	negative selection	637189
3856125	3856148	9	+	26472758	K562	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	0.24742747753878508	[478]	[479]	2	hSpCas9	negative selection	637190
3829314	3829337	9	+	26627737	DLD1	viability	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-0.16750217689800473	[222]	[92,65,31]	-2	hSpCas9	negative selection	843041
3937027	3937050	9	+	26627737	DLD1	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.7124211059781733	[296]	[143,196,121]	7	hSpCas9	negative selection	843056
4118789	4118812	9	-	26627737	DLD1	viability	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	-1.442336878528371	[458]	[47,30,74]	-8	hSpCas9	negative selection	843057
4125778	4125801	9	-	26627737	DLD1	viability	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.20810372601772598	[730]	[291,271,232]	2	hSpCas9	negative selection	843058
4286229	4286252	9	-	26627737	DLD1	viability	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.15028495381762141	[253]	[80,79,100]	1	hSpCas9	negative selection	843059
3829314	3829337	9	+	26627737	GBM cells	viability after 5 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	0.05436839351966494	[166]	[88,96]	0	hSpCas9	negative selection	925356
3937027	3937050	9	+	26627737	GBM cells	viability after 5 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.7321603300753136	[141]	[100,151]	8	hSpCas9	negative selection	925371
4118789	4118812	9	-	26627737	GBM cells	viability after 5 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	0.6683009467442693	[131]	[98,125]	8	hSpCas9	negative selection	925372
4125778	4125801	9	-	26627737	GBM cells	viability after 5 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.2107837697021533	[518]	[220,259]	-3	hSpCas9	negative selection	925373
4286229	4286252	9	-	26627737	GBM cells	viability after 5 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.8778522593578559	[68]	[85,49]	9	hSpCas9	negative selection	925374
3829314	3829337	9	+	26627737	GBM cells	viability after 13 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	0.39357312352347973	[166]	[107,127]	5	hSpCas9	negative selection	1007671
3937027	3937050	9	+	26627737	GBM cells	viability after 13 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.7178631313654872	[141]	[118,132]	8	hSpCas9	negative selection	1007686
4118789	4118812	9	-	26627737	GBM cells	viability after 13 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	0.7280627035636839	[131]	[68,158]	8	hSpCas9	negative selection	1007687
4125778	4125801	9	-	26627737	GBM cells	viability after 13 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.14413565071632428	[518]	[410,229]	1	hSpCas9	negative selection	1007688
4286229	4286252	9	-	26627737	GBM cells	viability after 13 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.866335807720131	[68]	[86,52]	8	hSpCas9	negative selection	1007689
3829314	3829337	9	+	26627737	GBM cells	viability after 21 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	0.34952659475492276	[166]	[124,106]	3	hSpCas9	negative selection	1089986
3937027	3937050	9	+	26627737	GBM cells	viability after 21 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.7269753613138253	[141]	[134,120]	7	hSpCas9	negative selection	1090001
4118789	4118812	9	-	26627737	GBM cells	viability after 21 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	1.8141365192018892	[131]	[247,255]	9	hSpCas9	negative selection	1090002
4125778	4125801	9	-	26627737	GBM cells	viability after 21 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.08228339318108713	[518]	[309,287]	0	hSpCas9	negative selection	1090003
4286229	4286252	9	-	26627737	GBM cells	viability after 21 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	1.2601738644653593	[68]	[82,95]	9	hSpCas9	negative selection	1090004
3829314	3829337	9	+	26627737	RPE1	viability after 9 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-1.4408775876524123	[575]	[89,35]	-8	hSpCas9	negative selection	1172301
3937027	3937050	9	+	26627737	RPE1	viability after 9 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	2.448346330552038	[106]	[160,210]	9	hSpCas9	negative selection	1172316
4118789	4118812	9	-	26627737	RPE1	viability after 9 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	-1.6560778564871081	[528]	[45,60]	-8	hSpCas9	negative selection	1172317
4125778	4125801	9	-	26627737	RPE1	viability after 9 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.3167226252768871	[1694]	[453,389]	-2	hSpCas9	negative selection	1172318
4286229	4286252	9	-	26627737	RPE1	viability after 9 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.41814967403250236	[163]	[120,0]	3	hSpCas9	negative selection	1172319
3829314	3829337	9	+	26627737	RPE1	viability after 12 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-2.1176943878518926	[575]	[40,29]	-8	hSpCas9	negative selection	1254616
3937027	3937050	9	+	26627737	RPE1	viability after 12 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	2.4755416554917775	[106]	[121,199]	9	hSpCas9	negative selection	1254631
4118789	4118812	9	-	26627737	RPE1	viability after 12 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	-0.5660499997197318	[528]	[129,59]	-4	hSpCas9	negative selection	1254632
4125778	4125801	9	-	26627737	RPE1	viability after 12 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.09702281571309412	[1694]	[400,451]	0	hSpCas9	negative selection	1254633
4286229	4286252	9	-	26627737	RPE1	viability after 12 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	-0.44097649038523024	[163]	[47,15]	-3	hSpCas9	negative selection	1254634
3829314	3829337	9	+	26627737	RPE1	viability after 15 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-1.8768503431126704	[575]	[51,36]	-8	hSpCas9	negative selection	1336931
3937027	3937050	9	+	26627737	RPE1	viability after 15 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	2.092874828546128	[106]	[65,189]	8	hSpCas9	negative selection	1336946
4118789	4118812	9	-	26627737	RPE1	viability after 15 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	-0.9252347451594779	[528]	[89,67]	-5	hSpCas9	negative selection	1336947
4125778	4125801	9	-	26627737	RPE1	viability after 15 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.39469522680030944	[1694]	[436,294]	-2	hSpCas9	negative selection	1336948
4286229	4286252	9	-	26627737	RPE1	viability after 15 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.012173110561609413	[163]	[86,7]	0	hSpCas9	negative selection	1336949
3829314	3829337	9	+	26627737	RPE1	viability after 18 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-1.862924123771907	[575]	[34,50]	-8	hSpCas9	negative selection	1419246
3937027	3937050	9	+	26627737	RPE1	viability after 18 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	2.102783515694245	[106]	[124,122]	8	hSpCas9	negative selection	1419261
4118789	4118812	9	-	26627737	RPE1	viability after 18 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	-0.24516223038466178	[528]	[220,12]	-1	hSpCas9	negative selection	1419262
4125778	4125801	9	-	26627737	RPE1	viability after 18 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.0777260603651615	[1694]	[314,559]	0	hSpCas9	negative selection	1419263
4286229	4286252	9	-	26627737	RPE1	viability after 18 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	-0.4915809257218178	[163]	[59,0]	-3	hSpCas9	negative selection	1419264
3829314	3829337	9	+	26627737	HeLa	viability after 8 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-0.9172807320452571	[380]	[143,47,83]	-7	hSpCas9	negative selection	1501561
3937027	3937050	9	+	26627737	HeLa	viability after 8 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.6155567066260196	[268]	[189,135,211]	5	hSpCas9	negative selection	1501576
4118789	4118812	9	-	26627737	HeLa	viability after 8 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	1.0060895432295132	[132]	[122,196,35]	7	hSpCas9	negative selection	1501577
4125778	4125801	9	-	26627737	HeLa	viability after 8 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.19066102951558705	[763]	[371,307,216]	-2	hSpCas9	negative selection	1501578
4286229	4286252	9	-	26627737	HeLa	viability after 8 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	-0.5301702156470087	[120]	[17,60,26]	-5	hSpCas9	negative selection	1501579
3829314	3829337	9	+	26627737	HeLa	viability after 12 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-0.4501691352795245	[380]	[137,137,67]	-4	hSpCas9	negative selection	1583876
3937027	3937050	9	+	26627737	HeLa	viability after 12 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	1.1181520739685151	[268]	[163,143,423]	7	hSpCas9	negative selection	1583891
4118789	4118812	9	-	26627737	HeLa	viability after 12 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	1.31402785672006	[132]	[179,53,185]	8	hSpCas9	negative selection	1583892
4125778	4125801	9	-	26627737	HeLa	viability after 12 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.34203335877580054	[763]	[338,181,235]	-3	hSpCas9	negative selection	1583893
4286229	4286252	9	-	26627737	HeLa	viability after 12 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	-0.7508411592922881	[120]	[11,63,8]	-6	hSpCas9	negative selection	1583894
3829314	3829337	9	+	26627737	HeLa	viability after 15 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-2.4863184612058373	[380]	[14,42,24]	-9	hSpCas9	negative selection	1666191
3937027	3937050	9	+	26627737	HeLa	viability after 15 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	1.2929503267663711	[268]	[464,122,209]	8	hSpCas9	negative selection	1666206
4118789	4118812	9	-	26627737	HeLa	viability after 15 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	0.36697601245335143	[132]	[48,99,59]	3	hSpCas9	negative selection	1666207
4125778	4125801	9	-	26627737	HeLa	viability after 15 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.2194332180082721	[763]	[322,206,270]	-2	hSpCas9	negative selection	1666208
4286229	4286252	9	-	26627737	HeLa	viability after 15 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	-0.4468326101408344	[120]	[43,31,31]	-4	hSpCas9	negative selection	1666209
3829314	3829337	9	+	26627737	HeLa	viability after 18 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-2.411870437296906	[380]	[10,37,24]	-9	hSpCas9	negative selection	1748506
3937027	3937050	9	+	26627737	HeLa	viability after 18 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	1.2580422897443024	[268]	[300,99,209]	8	hSpCas9	negative selection	1748521
4118789	4118812	9	-	26627737	HeLa	viability after 18 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	0.42404487903049626	[132]	[34,86,59]	3	hSpCas9	negative selection	1748522
4125778	4125801	9	-	26627737	HeLa	viability after 18 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.20738861726556768	[763]	[214,178,270]	-2	hSpCas9	negative selection	1748523
4286229	4286252	9	-	26627737	HeLa	viability after 18 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	-0.4288851457688492	[120]	[29,26,31]	-4	hSpCas9	negative selection	1748524
3829314	3829337	9	+	26627737	HCT116	viability after 6 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-1.6736830461645935	[155]	[17,1]	-7	hSpCas9	negative selection	1830821
3937027	3937050	9	+	26627737	HCT116	viability after 6 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	-0.7880334233947307	[603]	[112,22]	-4	hSpCas9	negative selection	1830836
4118789	4118812	9	-	26627737	HCT116	viability after 6 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	-0.925473397956946	[395]	[35,30]	-5	hSpCas9	negative selection	1830837
4125778	4125801	9	-	26627737	HCT116	viability after 6 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	1.0791830310082235	[686]	[155,267]	6	hSpCas9	negative selection	1830838
4286229	4286252	9	-	26627737	HCT116	viability after 6 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	2.5153022921142933	[97]	[2,134]	9	hSpCas9	negative selection	1830839
3829314	3829337	9	+	26627737	HCT116	viability after 8 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-0.36824099137552535	[192]	[111,77,57]	-4	hSpCas9	negative selection	1913136
3937027	3937050	9	+	26627737	HCT116	viability after 8 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.14927522202286342	[330]	[178,191,234]	1	hSpCas9	negative selection	1913151
4118789	4118812	9	-	26627737	HCT116	viability after 8 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	-0.2774800392337857	[109]	[34,84,29]	-3	hSpCas9	negative selection	1913152
4125778	4125801	9	-	26627737	HCT116	viability after 8 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.38780527683411037	[678]	[331,265,260]	-4	hSpCas9	negative selection	1913153
4286229	4286252	9	-	26627737	HCT116	viability after 8 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.7652225536257531	[99]	[73,144,61]	7	hSpCas9	negative selection	1913154
3829314	3829337	9	+	26627737	HCT116	viability after 9 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-0.506829738186358	[155]	[11,42]	-4	hSpCas9	negative selection	1995451
3937027	3937050	9	+	26627737	HCT116	viability after 9 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.23404446073474006	[603]	[206,175]	1	hSpCas9	negative selection	1995466
4118789	4118812	9	-	26627737	HCT116	viability after 9 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	0.6961435128661877	[395]	[91,233]	5	hSpCas9	negative selection	1995467
4125778	4125801	9	-	26627737	HCT116	viability after 9 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.03817510014515493	[686]	[203,175]	0	hSpCas9	negative selection	1995468
4286229	4286252	9	-	26627737	HCT116	viability after 9 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	2.1227138653571886	[97]	[99,124]	9	hSpCas9	negative selection	1995469
3829314	3829337	9	+	26627737	HCT116	viability after 12 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-0.33393488787713643	[192]	[85,124,30]	-4	hSpCas9	negative selection	2077766
3937027	3937050	9	+	26627737	HCT116	viability after 12 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.027069105433467883	[330]	[140,221,172]	0	hSpCas9	negative selection	2077781
4118789	4118812	9	-	26627737	HCT116	viability after 12 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	-0.620477343833679	[109]	[30,62,19]	-6	hSpCas9	negative selection	2077782
4125778	4125801	9	-	26627737	HCT116	viability after 12 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.5096990756887074	[678]	[185,309,262]	-5	hSpCas9	negative selection	2077783
4286229	4286252	9	-	26627737	HCT116	viability after 12 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.619142543428345	[99]	[98,57,82]	6	hSpCas9	negative selection	2077784
3829314	3829337	9	+	26627737	HCT116	viability after 15 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	0.209469590634755	[192]	[111,99,169]	2	hSpCas9	negative selection	2160081
3937027	3937050	9	+	26627737	HCT116	viability after 15 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.12666223023678513	[330]	[389,145,109]	1	hSpCas9	negative selection	2160096
4118789	4118812	9	-	26627737	HCT116	viability after 15 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	-0.3561369993403567	[109]	[40,52,52]	-4	hSpCas9	negative selection	2160097
4125778	4125801	9	-	26627737	HCT116	viability after 15 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.41808303867418484	[678]	[232,312,321]	-4	hSpCas9	negative selection	2160098
4286229	4286252	9	-	26627737	HCT116	viability after 15 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.18524383668613376	[99]	[92,18,86]	1	hSpCas9	negative selection	2160099
3829314	3829337	9	+	26627737	HCT116	viability after 18 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	0.49538231689543716	[192]	[164,62,172]	4	hSpCas9	negative selection	2242396
3937027	3937050	9	+	26627737	HCT116	viability after 18 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.4390294371254612	[330]	[242,238,164]	4	hSpCas9	negative selection	2242411
4118789	4118812	9	-	26627737	HCT116	viability after 18 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	-0.00975775659003908	[109]	[60,61,33]	0	hSpCas9	negative selection	2242412
4125778	4125801	9	-	26627737	HCT116	viability after 18 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.7834793869302181	[678]	[259,111,205]	-6	hSpCas9	negative selection	2242413
4286229	4286252	9	-	26627737	HCT116	viability after 18 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.12938788428591463	[99]	[32,57,67]	1	hSpCas9	negative selection	2242414
4118863	4118886	9	+	24336569	HL60	viability	CTCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	0.37641639965568274	[422]	[1161]	3	hSpCas9	negative selection	2268006
4125725	4125748	9	+	24336569	HL60	viability	ACTTGAGACCTGGTATCTGAAGG	GLIS3	ENSG00000107249	-0.6591586008860133	[593]	[795]	-5	hSpCas9	negative selection	2268007
4125733	4125756	9	-	24336569	HL60	viability	ATATACCTCCTTCAGATACCAGG	GLIS3	ENSG00000107249	-0.40544293508102064	[439]	[702]	-4	hSpCas9	negative selection	2268008
4125738	4125761	9	+	24336569	HL60	viability	TATCTGAAGGAGGTATATTCAGG	GLIS3	ENSG00000107249	0.1731087264567014	[227]	[543]	1	hSpCas9	negative selection	2268009
4125770	4125793	9	+	24336569	HL60	viability	TTCATTGCCCTCTGTAAGCTAGG	GLIS3	ENSG00000107249	-0.9126057868809367	[450]	[506]	-7	hSpCas9	negative selection	2268010
4125777	4125800	9	-	24336569	HL60	viability	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	-0.023643446240554145	[806]	[1679]	0	hSpCas9	negative selection	2268011
4125801	4125824	9	+	24336569	HL60	viability	GGTTGCATGCTGTAGAGACCTGG	GLIS3	ENSG00000107249	1.9941809527139969	[136]	[1154]	9	hSpCas9	negative selection	2268012
4125809	4125832	9	+	24336569	HL60	viability	GCTGTAGAGACCTGGCTTGCTGG	GLIS3	ENSG00000107249	-0.3578923232023148	[908]	[1500]	-3	hSpCas9	negative selection	2268013
4125819	4125842	9	-	24336569	HL60	viability	CATTTCACCTCCAGCAAGCCAGG	GLIS3	ENSG00000107249	0.3699968068998211	[263]	[721]	3	hSpCas9	negative selection	2268014
4125844	4125867	9	+	24336569	HL60	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.2119143378088983	[591]	[1450]	2	hSpCas9	negative selection	2268015
4118863	4118886	9	+	24336569	KBM7	viability	CTCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	0.7166602998370681	[451]	[2025]	6	hSpCas9	negative selection	2335183
4125725	4125748	9	+	24336569	KBM7	viability	ACTTGAGACCTGGTATCTGAAGG	GLIS3	ENSG00000107249	1.1008574281471597	[179]	[1052]	8	hSpCas9	negative selection	2335184
4125733	4125756	9	-	24336569	KBM7	viability	ATATACCTCCTTCAGATACCAGG	GLIS3	ENSG00000107249	-0.28601766804119677	[172]	[386]	-2	hSpCas9	negative selection	2335185
4125738	4125761	9	+	24336569	KBM7	viability	TATCTGAAGGAGGTATATTCAGG	GLIS3	ENSG00000107249	0.864433429473397	[145]	[724]	7	hSpCas9	negative selection	2335186
4125770	4125793	9	+	24336569	KBM7	viability	TTCATTGCCCTCTGTAAGCTAGG	GLIS3	ENSG00000107249	0.5063168338825141	[309]	[1200]	4	hSpCas9	negative selection	2335187
4125777	4125800	9	-	24336569	KBM7	viability	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	-0.016899747429897694	[515]	[1390]	0	hSpCas9	negative selection	2335188
4125801	4125824	9	+	24336569	KBM7	viability	GGTTGCATGCTGTAGAGACCTGG	GLIS3	ENSG00000107249	0.6405887168214883	[360]	[1534]	6	hSpCas9	negative selection	2335189
4125809	4125832	9	+	24336569	KBM7	viability	GCTGTAGAGACCTGGCTTGCTGG	GLIS3	ENSG00000107249	0.7144252890536666	[689]	[3087]	6	hSpCas9	negative selection	2335190
4125819	4125842	9	-	24336569	KBM7	viability	CATTTCACCTCCAGCAAGCCAGG	GLIS3	ENSG00000107249	0.5705428217255422	[355]	[1441]	5	hSpCas9	negative selection	2335191
4125844	4125867	9	+	24336569	KBM7	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	1.0431257142519115	[418]	[2354]	8	hSpCas9	negative selection	2335192
4260422	4260445	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCACCTGCCACCACGCCAAG	GLIS3	ENSG00000107249	3.5563442726279137	[263,282]	[1245,134]	9	dCas9-VP64	positive selection	2389719
4218728	4218751	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAATAGCCACATGTGGCTAATGG	GLIS3	ENSG00000107249	4.235590686841516	[113,29]	[561,9]	9	dCas9-VP64	positive selection	2397626
4196406	4196429	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGAACAAAGCTTCCACAGTGCGG	GLIS3	ENSG00000107249	-0.5496697636917173	[196,97]	[26,15]	-3	dCas9-VP64	positive selection	2400467
4075364	4075387	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGACCATCCTGGCTAACAAGG	GLIS3	ENSG00000107249	-1.1174807317499718	[30,74]	[4,4]	-6	dCas9-VP64	positive selection	2405373
4176886	4176909	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGTGTTGGGATTACAGGCGTAAG	GLIS3	ENSG00000107249	2.32900186243451	[2,3]	[4,1]	7	dCas9-VP64	positive selection	2408249
4053098	4053121	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCCAGATGTGGGGG	GLIS3	ENSG00000107249	-1.3435530862005833	[526,335]	[46,25]	-7	dCas9-VP64	positive selection	2413570
4025135	4025158	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTCAGCCTCCCGAGTAGCGAG	GLIS3	ENSG00000107249	0.5805591546882161	[16,8]	[5,1]	2	dCas9-VP64	positive selection	2421384
4283307	4283330	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCATTGCACTCCAGCCGGG	GLIS3	ENSG00000107249	3.359380449218091	[189,5]	[417,3]	8	dCas9-VP64	positive selection	2446640
4059798	4059821	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACACACACACACACAAATAAAG	GLIS3	ENSG00000107249	0.5857269793023226	[106,13]	[30,7]	2	dCas9-VP64	positive selection	2447820
3934483	3934506	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCCGCCTCCCGAG	GLIS3	ENSG00000107249	0.6259309833286419	[228,309]	[35,151]	2	dCas9-VP64	positive selection	2450461
4235154	4235177	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCAGGTGCCACCACGCCCAG	GLIS3	ENSG00000107249	-0.4083852587886121	[270,115]	[25,36]	-2	dCas9-VP64	positive selection	2458705
4152268	4152291	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACCCCGTCGTGTATTCTTCCAGG	GLIS3	ENSG00000107249	0.6449658191772993	[351,157]	[150,17]	2	dCas9-VP64	positive selection	2467445
4152294	4152317	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGATATTGCAGAGAATGTAGG	GLIS3	ENSG00000107249	5.692005124820585	[40,64]	[1176,7]	9	dCas9-VP64	positive selection	2467446
4152355	4152378	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCAACTCTATAACATCTCAAAGG	GLIS3	ENSG00000107249	-1.259248455325759	[127,63]	[9,5]	-7	dCas9-VP64	positive selection	2467447
4179832	4179855	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGTAGCCTCTGCCTCCCGGG	GLIS3	ENSG00000107249	0.2616905918350563	[440,321]	[140,55]	1	dCas9-VP64	positive selection	2471941
4161752	4161775	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGTAGCCTCTGCCTCCCAGG	GLIS3	ENSG00000107249	0.2616905918350563	[440,321]	[140,55]	1	dCas9-VP64	positive selection	2471965
4179630	4179653	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAGCGTGAGCCACCGTGCCTGG	GLIS3	ENSG00000107249	1.3051580023585738	[14,7]	[5,4]	5	dCas9-VP64	positive selection	2476751
4260422	4260445	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCACCTGCCACCACGCCAAG	GLIS3	ENSG00000107249	0.46315742416717276	[258,245]	[121,105]	3	dCas9-VP64	positive selection	2484974
4218728	4218751	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAATAGCCACATGTGGCTAATGG	GLIS3	ENSG00000107249	0.4878564578918625	[26,36]	[8,18]	4	dCas9-VP64	positive selection	2492881
4196406	4196429	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGAACAAAGCTTCCACAGTGCGG	GLIS3	ENSG00000107249	0.8045950814528624	[213,99]	[100,79]	5	dCas9-VP64	positive selection	2495722
4075364	4075387	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGACCATCCTGGCTAACAAGG	GLIS3	ENSG00000107249	-0.3866569806865121	[139,148]	[35,34]	-4	dCas9-VP64	positive selection	2500628
4176886	4176909	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGTGTTGGGATTACAGGCGTAAG	GLIS3	ENSG00000107249	-0.3752571813335419	[45,18]	[9,5]	-4	dCas9-VP64	positive selection	2503504
4053098	4053121	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCCAGATGTGGGGG	GLIS3	ENSG00000107249	0.12779844081241276	[54,202]	[74,16]	1	dCas9-VP64	positive selection	2508825
4025135	4025158	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTCAGCCTCCCGAGTAGCGAG	GLIS3	ENSG00000107249	0.21208715000527545	[37,95]	[24,24]	1	dCas9-VP64	positive selection	2516639
4283307	4283330	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCATTGCACTCCAGCCGGG	GLIS3	ENSG00000107249	0.626840615877442	[158,168]	[52,109]	4	dCas9-VP64	positive selection	2541895
4059798	4059821	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACACACACACACACAAATAAAG	GLIS3	ENSG00000107249	2.993191744647718	[42,43]	[29,191]	9	dCas9-VP64	positive selection	2543075
3934483	3934506	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCCGCCTCCCGAG	GLIS3	ENSG00000107249	0.8832307312434098	[227,267]	[69,222]	6	dCas9-VP64	positive selection	2545716
4235154	4235177	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCAGGTGCCACCACGCCCAG	GLIS3	ENSG00000107249	-0.7887530655441356	[186,58]	[27,18]	-7	dCas9-VP64	positive selection	2553960
4152268	4152291	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACCCCGTCGTGTATTCTTCCAGG	GLIS3	ENSG00000107249	2.2062554199254922	[64,163]	[20,311]	8	dCas9-VP64	positive selection	2562700
4152294	4152317	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGATATTGCAGAGAATGTAGG	GLIS3	ENSG00000107249	0.09557126725564752	[108,180]	[75,25]	0	dCas9-VP64	positive selection	2562701
4152355	4152378	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCAACTCTATAACATCTCAAAGG	GLIS3	ENSG00000107249	-0.8532538095813638	[192,251]	[41,37]	-7	dCas9-VP64	positive selection	2562702
4179832	4179855	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGTAGCCTCTGCCTCCCGGG	GLIS3	ENSG00000107249	-0.08717723700505853	[194,489]	[29,173]	0	dCas9-VP64	positive selection	2567196
4161752	4161775	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGTAGCCTCTGCCTCCCAGG	GLIS3	ENSG00000107249	-0.08717723700505853	[194,489]	[29,173]	0	dCas9-VP64	positive selection	2567220
4179630	4179653	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAGCGTGAGCCACCGTGCCTGG	GLIS3	ENSG00000107249	1.1554864993418033	[20,247]	[176,21]	7	dCas9-VP64	positive selection	2572006
4125844	4125867	9	+	27260157	DLD1	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.284880383469259	[]	[]	4	hSpCas9	negative selection	2574433
4286203	4286226	9	-	27260157	DLD1	viability	GATGGCTCCTCAGAACAACGTGG	GLIS3	ENSG00000107249	0.914168938169532	[]	[]	9	hSpCas9	negative selection	2576596
4118863	4118886	9	+	27260157	DLD1	viability	CTCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	-0.669270101549302	[]	[]	-5	hSpCas9	negative selection	2579643
4286310	4286333	9	-	27260157	DLD1	viability	CGAGCCCACTCCGGGACTCCTGG	GLIS3	ENSG00000107249	0.961584563755789	[]	[]	9	hSpCas9	negative selection	2581163
4125899	4125922	9	-	27260157	DLD1	viability	CAGTGCAAGTCCATTGGAAAAGG	GLIS3	ENSG00000107249	0.859350131943021	[]	[]	9	hSpCas9	negative selection	2581407
4125801	4125824	9	+	27260157	DLD1	viability	GGTTGCATGCTGTAGAGACCTGG	GLIS3	ENSG00000107249	-0.587696507632629	[]	[]	-5	hSpCas9	negative selection	2583023
4118856	4118879	9	-	27260157	DLD1	viability	CCTTATTTCGCGTGAGTCTTTGG	GLIS3	ENSG00000107249	-0.14266226840531	[]	[]	-1	hSpCas9	negative selection	2583245
4125733	4125756	9	-	27260157	DLD1	viability	ATATACCTCCTTCAGATACCAGG	GLIS3	ENSG00000107249	-0.0605140446540957	[]	[]	0	hSpCas9	negative selection	2585726
4125845	4125868	9	-	27260157	DLD1	viability	CCCATGATGGTTCAGCGACTGGG	GLIS3	ENSG00000107249	1.00702671009411	[]	[]	9	hSpCas9	negative selection	2605913
4125819	4125842	9	-	27260157	DLD1	viability	CATTTCACCTCCAGCAAGCCAGG	GLIS3	ENSG00000107249	0.293996898131765	[]	[]	4	hSpCas9	negative selection	2605968
4152113	4152136	9	-	27260157	DLD1	viability	GCTGAAGTGGCAACTAATAGAGG	GLIS3	ENSG00000107249	-0.197591880888575	[]	[]	-1	hSpCas9	negative selection	2613768
4118856	4118879	9	+	27260157	DLD1	viability	CCAAAGACTCACGCGAAATAAGG	GLIS3	ENSG00000107249	0.491764905765948	[]	[]	8	hSpCas9	negative selection	2614612
4125777	4125800	9	-	27260157	DLD1	viability	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	0.741772964715029	[]	[]	8	hSpCas9	negative selection	2615030
4152159	4152182	9	+	27260157	DLD1	viability	CCAACACCCTTCAACCATAAAGG	GLIS3	ENSG00000107249	1.03825087566378	[]	[]	9	hSpCas9	negative selection	2617208
4125738	4125761	9	+	27260157	DLD1	viability	TATCTGAAGGAGGTATATTCAGG	GLIS3	ENSG00000107249	-1.5171444737284	[]	[]	-8	hSpCas9	negative selection	2618925
4286232	4286255	9	-	27260157	DLD1	viability	CTCCATCTCAAGATGCCCTCAGG	GLIS3	ENSG00000107249	1.06912099760954	[]	[]	9	hSpCas9	negative selection	2642806
4125809	4125832	9	+	27260157	DLD1	viability	GCTGTAGAGACCTGGCTTGCTGG	GLIS3	ENSG00000107249	0.992601260933076	[]	[]	9	hSpCas9	negative selection	2643989
4118753	4118776	9	+	27260157	DLD1	viability	GAGCCGTGGTTGGAGAGCGAAGG	GLIS3	ENSG00000107249	1.147039262568	[]	[]	9	hSpCas9	negative selection	2644643
4125725	4125748	9	+	27260157	DLD1	viability	ACTTGAGACCTGGTATCTGAAGG	GLIS3	ENSG00000107249	0.0625947408543256	[]	[]	3	hSpCas9	negative selection	2644913
4125770	4125793	9	+	27260157	DLD1	viability	TTCATTGCCCTCTGTAAGCTAGG	GLIS3	ENSG00000107249	0.0111516474645895	[]	[]	0	hSpCas9	negative selection	2647437
4125844	4125867	9	+	27260157	HT1080	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.150674126960807	[]	[]	1	hSpCas9	negative selection	2650563
4286203	4286226	9	-	27260157	HT1080	viability	GATGGCTCCTCAGAACAACGTGG	GLIS3	ENSG00000107249	0.709944912539062	[]	[]	6	hSpCas9	negative selection	2652726
4118863	4118886	9	+	27260157	HT1080	viability	CTCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	-0.211007767825277	[]	[]	0	hSpCas9	negative selection	2655773
4286310	4286333	9	-	27260157	HT1080	viability	CGAGCCCACTCCGGGACTCCTGG	GLIS3	ENSG00000107249	0.559879624190185	[]	[]	5	hSpCas9	negative selection	2657293
4125899	4125922	9	-	27260157	HT1080	viability	CAGTGCAAGTCCATTGGAAAAGG	GLIS3	ENSG00000107249	1.60979979218889	[]	[]	9	hSpCas9	negative selection	2657537
4125801	4125824	9	+	27260157	HT1080	viability	GGTTGCATGCTGTAGAGACCTGG	GLIS3	ENSG00000107249	-2.20245688554558	[]	[]	-9	hSpCas9	negative selection	2659153
4118856	4118879	9	-	27260157	HT1080	viability	CCTTATTTCGCGTGAGTCTTTGG	GLIS3	ENSG00000107249	-0.652776306519946	[]	[]	-8	hSpCas9	negative selection	2659375
4125733	4125756	9	-	27260157	HT1080	viability	ATATACCTCCTTCAGATACCAGG	GLIS3	ENSG00000107249	-0.0433995420005864	[]	[]	0	hSpCas9	negative selection	2661856
4125845	4125868	9	-	27260157	HT1080	viability	CCCATGATGGTTCAGCGACTGGG	GLIS3	ENSG00000107249	0.352931304174308	[]	[]	3	hSpCas9	negative selection	2682043
4125819	4125842	9	-	27260157	HT1080	viability	CATTTCACCTCCAGCAAGCCAGG	GLIS3	ENSG00000107249	0.65315954822328	[]	[]	6	hSpCas9	negative selection	2682098
4152113	4152136	9	-	27260157	HT1080	viability	GCTGAAGTGGCAACTAATAGAGG	GLIS3	ENSG00000107249	-0.119761530809482	[]	[]	0	hSpCas9	negative selection	2689898
4118856	4118879	9	+	27260157	HT1080	viability	CCAAAGACTCACGCGAAATAAGG	GLIS3	ENSG00000107249	0.412766306467136	[]	[]	4	hSpCas9	negative selection	2690742
4125777	4125800	9	-	27260157	HT1080	viability	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	0.580681504030119	[]	[]	5	hSpCas9	negative selection	2691160
4152159	4152182	9	+	27260157	HT1080	viability	CCAACACCCTTCAACCATAAAGG	GLIS3	ENSG00000107249	1.18742569268748	[]	[]	8	hSpCas9	negative selection	2693338
4125738	4125761	9	+	27260157	HT1080	viability	TATCTGAAGGAGGTATATTCAGG	GLIS3	ENSG00000107249	-0.43375221269041	[]	[]	-7	hSpCas9	negative selection	2695055
4286232	4286255	9	-	27260157	HT1080	viability	CTCCATCTCAAGATGCCCTCAGG	GLIS3	ENSG00000107249	-0.00856929493108546	[]	[]	0	hSpCas9	negative selection	2718936
4125809	4125832	9	+	27260157	HT1080	viability	GCTGTAGAGACCTGGCTTGCTGG	GLIS3	ENSG00000107249	0.133438043943157	[]	[]	1	hSpCas9	negative selection	2720119
4118753	4118776	9	+	27260157	HT1080	viability	GAGCCGTGGTTGGAGAGCGAAGG	GLIS3	ENSG00000107249	-0.116078877263131	[]	[]	0	hSpCas9	negative selection	2720773
4125725	4125748	9	+	27260157	HT1080	viability	ACTTGAGACCTGGTATCTGAAGG	GLIS3	ENSG00000107249	-0.570841659238031	[]	[]	-7	hSpCas9	negative selection	2721043
4125770	4125793	9	+	27260157	HT1080	viability	TTCATTGCCCTCTGTAAGCTAGG	GLIS3	ENSG00000107249	-0.547674242131106	[]	[]	-7	hSpCas9	negative selection	2723567
4125844	4125867	9	+	27260157	MKN45	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	1.0072770265866	[]	[]	8	hSpCas9	negative selection	2726693
4286203	4286226	9	-	27260157	MKN45	viability	GATGGCTCCTCAGAACAACGTGG	GLIS3	ENSG00000107249	0.998439485801235	[]	[]	8	hSpCas9	negative selection	2728856
4118863	4118886	9	+	27260157	MKN45	viability	CTCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	-0.18924488743359	[]	[]	0	hSpCas9	negative selection	2731903
4286310	4286333	9	-	27260157	MKN45	viability	CGAGCCCACTCCGGGACTCCTGG	GLIS3	ENSG00000107249	0.74258984440463	[]	[]	7	hSpCas9	negative selection	2733423
4125899	4125922	9	-	27260157	MKN45	viability	CAGTGCAAGTCCATTGGAAAAGG	GLIS3	ENSG00000107249	1.23290709279138	[]	[]	9	hSpCas9	negative selection	2733667
4125801	4125824	9	+	27260157	MKN45	viability	GGTTGCATGCTGTAGAGACCTGG	GLIS3	ENSG00000107249	0.645605055327931	[]	[]	7	hSpCas9	negative selection	2735283
4118856	4118879	9	-	27260157	MKN45	viability	CCTTATTTCGCGTGAGTCTTTGG	GLIS3	ENSG00000107249	-0.633469426512129	[]	[]	-6	hSpCas9	negative selection	2735505
4125733	4125756	9	-	27260157	MKN45	viability	ATATACCTCCTTCAGATACCAGG	GLIS3	ENSG00000107249	0.361395438953847	[]	[]	6	hSpCas9	negative selection	2737986
4125845	4125868	9	-	27260157	MKN45	viability	CCCATGATGGTTCAGCGACTGGG	GLIS3	ENSG00000107249	0.83264010642181	[]	[]	8	hSpCas9	negative selection	2758173
4125819	4125842	9	-	27260157	MKN45	viability	CATTTCACCTCCAGCAAGCCAGG	GLIS3	ENSG00000107249	0.992423794771645	[]	[]	8	hSpCas9	negative selection	2758228
4152113	4152136	9	-	27260157	MKN45	viability	GCTGAAGTGGCAACTAATAGAGG	GLIS3	ENSG00000107249	-0.067271826444675	[]	[]	0	hSpCas9	negative selection	2766028
4118856	4118879	9	+	27260157	MKN45	viability	CCAAAGACTCACGCGAAATAAGG	GLIS3	ENSG00000107249	-0.00474804517815701	[]	[]	0	hSpCas9	negative selection	2766872
4125777	4125800	9	-	27260157	MKN45	viability	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	0.570071861717576	[]	[]	7	hSpCas9	negative selection	2767290
4152159	4152182	9	+	27260157	MKN45	viability	CCAACACCCTTCAACCATAAAGG	GLIS3	ENSG00000107249	0.302610314737374	[]	[]	5	hSpCas9	negative selection	2769468
4125738	4125761	9	+	27260157	MKN45	viability	TATCTGAAGGAGGTATATTCAGG	GLIS3	ENSG00000107249	-0.573692953259044	[]	[]	-6	hSpCas9	negative selection	2771185
4286232	4286255	9	-	27260157	MKN45	viability	CTCCATCTCAAGATGCCCTCAGG	GLIS3	ENSG00000107249	1.12900365821921	[]	[]	8	hSpCas9	negative selection	2795066
4125809	4125832	9	+	27260157	MKN45	viability	GCTGTAGAGACCTGGCTTGCTGG	GLIS3	ENSG00000107249	-0.129244413485625	[]	[]	0	hSpCas9	negative selection	2796249
4118753	4118776	9	+	27260157	MKN45	viability	GAGCCGTGGTTGGAGAGCGAAGG	GLIS3	ENSG00000107249	0.656164239018684	[]	[]	7	hSpCas9	negative selection	2796903
4125725	4125748	9	+	27260157	MKN45	viability	ACTTGAGACCTGGTATCTGAAGG	GLIS3	ENSG00000107249	-0.149099913441525	[]	[]	0	hSpCas9	negative selection	2797173
4125770	4125793	9	+	27260157	MKN45	viability	TTCATTGCCCTCTGTAAGCTAGG	GLIS3	ENSG00000107249	0.498961758271175	[]	[]	6	hSpCas9	negative selection	2799697
4125844	4125867	9	+	27260157	RKO	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	-0.25775468377931	[]	[]	-1	hSpCas9	negative selection	2802823
4286203	4286226	9	-	27260157	RKO	viability	GATGGCTCCTCAGAACAACGTGG	GLIS3	ENSG00000107249	0.573238440735155	[]	[]	3	hSpCas9	negative selection	2804986
4118863	4118886	9	+	27260157	RKO	viability	CTCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	-0.112066166296217	[]	[]	0	hSpCas9	negative selection	2808033
4286310	4286333	9	-	27260157	RKO	viability	CGAGCCCACTCCGGGACTCCTGG	GLIS3	ENSG00000107249	0.884721460155504	[]	[]	8	hSpCas9	negative selection	2809553
4125899	4125922	9	-	27260157	RKO	viability	CAGTGCAAGTCCATTGGAAAAGG	GLIS3	ENSG00000107249	0.384353654214832	[]	[]	2	hSpCas9	negative selection	2809797
4125801	4125824	9	+	27260157	RKO	viability	GGTTGCATGCTGTAGAGACCTGG	GLIS3	ENSG00000107249	-0.41501713882991	[]	[]	-6	hSpCas9	negative selection	2811413
4118856	4118879	9	-	27260157	RKO	viability	CCTTATTTCGCGTGAGTCTTTGG	GLIS3	ENSG00000107249	-0.274920108827135	[]	[]	-1	hSpCas9	negative selection	2811635
4125733	4125756	9	-	27260157	RKO	viability	ATATACCTCCTTCAGATACCAGG	GLIS3	ENSG00000107249	0.308923122413216	[]	[]	1	hSpCas9	negative selection	2814116
4125845	4125868	9	-	27260157	RKO	viability	CCCATGATGGTTCAGCGACTGGG	GLIS3	ENSG00000107249	0.548185024308452	[]	[]	3	hSpCas9	negative selection	2834303
4125819	4125842	9	-	27260157	RKO	viability	CATTTCACCTCCAGCAAGCCAGG	GLIS3	ENSG00000107249	1.03611232272921	[]	[]	9	hSpCas9	negative selection	2834358
4152113	4152136	9	-	27260157	RKO	viability	GCTGAAGTGGCAACTAATAGAGG	GLIS3	ENSG00000107249	0.0300223576903115	[]	[]	0	hSpCas9	negative selection	2842158
4118856	4118879	9	+	27260157	RKO	viability	CCAAAGACTCACGCGAAATAAGG	GLIS3	ENSG00000107249	0.481908296826234	[]	[]	2	hSpCas9	negative selection	2843002
4125777	4125800	9	-	27260157	RKO	viability	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	0.300772344917994	[]	[]	1	hSpCas9	negative selection	2843420
4152159	4152182	9	+	27260157	RKO	viability	CCAACACCCTTCAACCATAAAGG	GLIS3	ENSG00000107249	0.141638725100668	[]	[]	0	hSpCas9	negative selection	2845598
4125738	4125761	9	+	27260157	RKO	viability	TATCTGAAGGAGGTATATTCAGG	GLIS3	ENSG00000107249	0.00894982951989558	[]	[]	0	hSpCas9	negative selection	2847315
4286232	4286255	9	-	27260157	RKO	viability	CTCCATCTCAAGATGCCCTCAGG	GLIS3	ENSG00000107249	0.887494593833167	[]	[]	8	hSpCas9	negative selection	2871196
4125809	4125832	9	+	27260157	RKO	viability	GCTGTAGAGACCTGGCTTGCTGG	GLIS3	ENSG00000107249	-0.200516095852201	[]	[]	-1	hSpCas9	negative selection	2872379
4118753	4118776	9	+	27260157	RKO	viability	GAGCCGTGGTTGGAGAGCGAAGG	GLIS3	ENSG00000107249	1.52604850748281	[]	[]	9	hSpCas9	negative selection	2873033
4125725	4125748	9	+	27260157	RKO	viability	ACTTGAGACCTGGTATCTGAAGG	GLIS3	ENSG00000107249	0.354756267405437	[]	[]	2	hSpCas9	negative selection	2873303
4125770	4125793	9	+	27260157	RKO	viability	TTCATTGCCCTCTGTAAGCTAGG	GLIS3	ENSG00000107249	0.500071587549313	[]	[]	2	hSpCas9	negative selection	2875827
4125844	4125867	9	+	27260157	SF268	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	1.25538711355187	[]	[]	9	hSpCas9	negative selection	2878953
4286203	4286226	9	-	27260157	SF268	viability	GATGGCTCCTCAGAACAACGTGG	GLIS3	ENSG00000107249	1.41082868819658	[]	[]	9	hSpCas9	negative selection	2881116
4118863	4118886	9	+	27260157	SF268	viability	CTCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	-0.408969037630298	[]	[]	-3	hSpCas9	negative selection	2884163
4286310	4286333	9	-	27260157	SF268	viability	CGAGCCCACTCCGGGACTCCTGG	GLIS3	ENSG00000107249	0.669270750835	[]	[]	8	hSpCas9	negative selection	2885683
4125899	4125922	9	-	27260157	SF268	viability	CAGTGCAAGTCCATTGGAAAAGG	GLIS3	ENSG00000107249	1.20984017911312	[]	[]	9	hSpCas9	negative selection	2885927
4125801	4125824	9	+	27260157	SF268	viability	GGTTGCATGCTGTAGAGACCTGG	GLIS3	ENSG00000107249	-0.579641747446651	[]	[]	-4	hSpCas9	negative selection	2887543
4118856	4118879	9	-	27260157	SF268	viability	CCTTATTTCGCGTGAGTCTTTGG	GLIS3	ENSG00000107249	-0.48081945862063	[]	[]	-4	hSpCas9	negative selection	2887765
4125733	4125756	9	-	27260157	SF268	viability	ATATACCTCCTTCAGATACCAGG	GLIS3	ENSG00000107249	-0.321122026008986	[]	[]	-3	hSpCas9	negative selection	2890246
4125845	4125868	9	-	27260157	SF268	viability	CCCATGATGGTTCAGCGACTGGG	GLIS3	ENSG00000107249	1.21901470483975	[]	[]	9	hSpCas9	negative selection	2910433
4125819	4125842	9	-	27260157	SF268	viability	CATTTCACCTCCAGCAAGCCAGG	GLIS3	ENSG00000107249	0.905286784792822	[]	[]	9	hSpCas9	negative selection	2910488
4152113	4152136	9	-	27260157	SF268	viability	GCTGAAGTGGCAACTAATAGAGG	GLIS3	ENSG00000107249	0.876115745414051	[]	[]	9	hSpCas9	negative selection	2918288
4118856	4118879	9	+	27260157	SF268	viability	CCAAAGACTCACGCGAAATAAGG	GLIS3	ENSG00000107249	-0.00701790571925076	[]	[]	0	hSpCas9	negative selection	2919132
4125777	4125800	9	-	27260157	SF268	viability	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	0.618120658572907	[]	[]	8	hSpCas9	negative selection	2919550
4152159	4152182	9	+	27260157	SF268	viability	CCAACACCCTTCAACCATAAAGG	GLIS3	ENSG00000107249	0.825467566950707	[]	[]	8	hSpCas9	negative selection	2921728
4125738	4125761	9	+	27260157	SF268	viability	TATCTGAAGGAGGTATATTCAGG	GLIS3	ENSG00000107249	0.576704204517302	[]	[]	8	hSpCas9	negative selection	2923445
4286232	4286255	9	-	27260157	SF268	viability	CTCCATCTCAAGATGCCCTCAGG	GLIS3	ENSG00000107249	1.33860279644676	[]	[]	9	hSpCas9	negative selection	2947326
4125809	4125832	9	+	27260157	SF268	viability	GCTGTAGAGACCTGGCTTGCTGG	GLIS3	ENSG00000107249	0.0838490356908857	[]	[]	0	hSpCas9	negative selection	2948509
4118753	4118776	9	+	27260157	SF268	viability	GAGCCGTGGTTGGAGAGCGAAGG	GLIS3	ENSG00000107249	0.808362648249699	[]	[]	8	hSpCas9	negative selection	2949163
4125725	4125748	9	+	27260157	SF268	viability	ACTTGAGACCTGGTATCTGAAGG	GLIS3	ENSG00000107249	-0.0259765677559391	[]	[]	0	hSpCas9	negative selection	2949433
4125770	4125793	9	+	27260157	SF268	viability	TTCATTGCCCTCTGTAAGCTAGG	GLIS3	ENSG00000107249	0.569434108022586	[]	[]	8	hSpCas9	negative selection	2951957
4125778	4125801	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.07961391046226723	[4,4]	[3,3]	-1	hSpCas9	positive selection	2990786
4125777	4125800	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	-0.5668630897327287	[3,3]	[0,2]	-7	hSpCas9	positive selection	2990787
4118205	4118228	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCGGGCCCCGACAGCCAGTCGG	GLIS3	ENSG00000107249	0.4092888086858135	[3,3]	[3,4]	8	hSpCas9	positive selection	2990788
4125813	4125836	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGAGACCTGGCTTGCTGGAGG	GLIS3	ENSG00000107249	-0.869152621475253	[2,2]	[1,0]	-8	hSpCas9	positive selection	2990789
4125778	4125801	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.28217573972113397	[4,4]	[3,4]	5	hSpCas9	positive selection	3058644
4125777	4125800	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	-0.176445598091088	[3,3]	[3,1]	-3	hSpCas9	positive selection	3058645
4118205	4118228	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCGGGCCCCGACAGCCAGTCGG	GLIS3	ENSG00000107249	0.06843860260681127	[3,3]	[3,1]	1	hSpCas9	positive selection	3058646
4125813	4125836	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGAGACCTGGCTTGCTGGAGG	GLIS3	ENSG00000107249	0.06954170035171806	[2,2]	[3,0]	1	hSpCas9	positive selection	3058647
4125778	4125801		-	24336571	A375	resistance to PLX after 7 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.5173950528163701	[11,12]	[16,18]	9	hSpCas9	positive selection	3116760
4125899	4125922		-	24336571	A375	resistance to PLX after 7 days	CAGTGCAAGTCCATTGGAAAAGG	GLIS3	ENSG00000107249	-0.06800464800192652	[7,7]	[7,6]	-2	hSpCas9	positive selection	3116761
4117908	4117931		-	24336571	A375	resistance to PLX after 7 days	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	-0.09020502285612766	[14,16]	[14,14]	-3	hSpCas9	positive selection	3116762
4125846	4125869		-	24336571	A375	resistance to PLX after 7 days	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.00015564227176152745	[14,11]	[12,13]	0	hSpCas9	positive selection	3116763
4125778	4125801		-	24336571	A375	resistance to PLX after 14 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.7104527099660436	[10,8]	[7,6]	6	hSpCas9	positive selection	3174553
4125899	4125922		-	24336571	A375	resistance to PLX after 14 days	CAGTGCAAGTCCATTGGAAAAGG	GLIS3	ENSG00000107249	-0.427758241730143	[4,8]	[1,1]	-5	hSpCas9	positive selection	3174554
4117908	4117931		-	24336571	A375	resistance to PLX after 14 days	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	-0.25026946815998574	[13,18]	[5,6]	-3	hSpCas9	positive selection	3174555
4125846	4125869		-	24336571	A375	resistance to PLX after 14 days	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.3489328953207885	[12,13]	[4,4]	-4	hSpCas9	positive selection	3174556
4125778	4125801		-	24336571	A375	viability after 7 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.5452849505665976	[19]	[11,12]	-7	hSpCas9	negative selection	3232346
4125899	4125922		-	24336571	A375	viability after 7 days	CAGTGCAAGTCCATTGGAAAAGG	GLIS3	ENSG00000107249	0.3695732575011238	[5]	[7,7]	5	hSpCas9	negative selection	3232347
4117908	4117931		-	24336571	A375	viability after 7 days	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.2836726314022302	[13]	[14,16]	4	hSpCas9	negative selection	3232348
4125846	4125869		-	24336571	A375	viability after 7 days	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.3987663268798753	[10]	[14,11]	6	hSpCas9	negative selection	3232349
4125778	4125801		-	24336571	A375	viability after 14 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.869271285087318	[19]	[10,8]	-8	hSpCas9	negative selection	3290139
4125899	4125922		-	24336571	A375	viability after 14 days	CAGTGCAAGTCCATTGGAAAAGG	GLIS3	ENSG00000107249	0.2978693620076077	[5]	[4,8]	4	hSpCas9	negative selection	3290140
4117908	4117931		-	24336571	A375	viability after 14 days	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.37393438020813646	[13]	[13,18]	5	hSpCas9	negative selection	3290141
4125846	4125869		-	24336571	A375	viability after 14 days	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.4432658971851536	[10]	[12,13]	5	hSpCas9	negative selection	3290142
4117908	4117931	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	5.229500583237637	[85,113]	[47,0]	9	hSpCas9	positive selection	3351637
4118473	4118496	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.39285680852583243	[119,112]	[0,0]	2	hSpCas9	positive selection	3351638
3937027	3937050	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.09725706908121846	[145,139]	[0,0]	0	hSpCas9	positive selection	3351639
4125846	4125869	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.47596649792117546	[109,109]	[0,0]	2	hSpCas9	positive selection	3370839
3937171	3937194	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.274055249070477	[184,184]	[0,0]	-2	hSpCas9	positive selection	3370840
4125844	4125867	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	-0.3829187247765107	[398,398]	[1,1]	-2	hSpCas9	positive selection	3370841
4125778	4125801	9	-	26780180	HT29	viability (Avana library 4 designs)	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.702856218964983	[]	[]	-8	hSpCas9	negative selection	3427939
4125777	4125800	9	-	26780180	HT29	viability (Avana library 4 designs)	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	0.12866598723838	[]	[]	0	hSpCas9	negative selection	3427940
4118205	4118228	9	-	26780180	HT29	viability (Avana library 4 designs)	GCCGGGCCCCGACAGCCAGTCGG	GLIS3	ENSG00000107249	0.551363098889522	[]	[]	2	hSpCas9	negative selection	3427941
4125812	4125835	9	+	26780180	HT29	viability (Avana library 4 designs)	GTAGAGACCTGGCTTGCTGGAGG	GLIS3	ENSG00000107249	0.626709003223361	[]	[]	2	hSpCas9	negative selection	3427942
4125777	4125800	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	-7.70782815287564	[]	[]	-7	hSpCas9	negative selection	3511783
4118205	4118228	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCGGGCCCCGACAGCCAGTCGG	GLIS3	ENSG00000107249	5.01823380120052	[]	[]	8	hSpCas9	negative selection	3511784
4125812	4125835	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGAGACCTGGCTTGCTGGAGG	GLIS3	ENSG00000107249	-1.58124276358323	[]	[]	-2	hSpCas9	negative selection	3511785
4125778	4125801	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-5.04702329522254	[]	[]	-5	hSpCas9	negative selection	3511786
4118781	4118804	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGTGGTCCCAGGGCTACAGGG	GLIS3	ENSG00000107249	5.67741169673597	[]	[]	8	hSpCas9	negative selection	3511787
4118175	4118198	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCAAGACCGAACGCCTGGAGG	GLIS3	ENSG00000107249	1.63205268934293	[]	[]	2	hSpCas9	negative selection	3511788
4125777	4125800	9	-	26780180	A375	viability (Avana lentiGuide)	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	3.67221294518127	[]	[]	3	hSpCas9	negative selection	3620442
4118205	4118228	9	-	26780180	A375	viability (Avana lentiGuide)	GCCGGGCCCCGACAGCCAGTCGG	GLIS3	ENSG00000107249	-6.18321825164488	[]	[]	-9	hSpCas9	negative selection	3620443
4125812	4125835	9	+	26780180	A375	viability (Avana lentiGuide)	GTAGAGACCTGGCTTGCTGGAGG	GLIS3	ENSG00000107249	11.4936010464768	[]	[]	7	hSpCas9	negative selection	3620444
4125778	4125801	9	-	26780180	A375	viability (Avana lentiGuide)	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	2.25508604262699	[]	[]	2	hSpCas9	negative selection	3620445
4118781	4118804	9	-	26780180	A375	viability (Avana lentiGuide)	GGAGTGGTCCCAGGGCTACAGGG	GLIS3	ENSG00000107249	-5.4726758864647	[]	[]	-8	hSpCas9	negative selection	3620446
4118175	4118198	9	-	26780180	A375	viability (Avana lentiGuide)	GTTCAAGACCGAACGCCTGGAGG	GLIS3	ENSG00000107249	-0.0157962862748336	[]	[]	0	hSpCas9	negative selection	3620447
4125777	4125800	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	-0.39529814983782585	[6]	[4,3]	-5	hSpCas9	positive selection	3729101
4118205	4118228	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCGGGCCCCGACAGCCAGTCGG	GLIS3	ENSG00000107249	0.37689580447278437	[3]	[6,3]	9	hSpCas9	positive selection	3729102
4125812	4125835	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGAGACCTGGCTTGCTGGAGG	GLIS3	ENSG00000107249	-0.14834150830591003	[3]	[3,3]	-2	hSpCas9	positive selection	3729103
4125778	4125801	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.15348678634493979	[6]	[4,5]	-2	hSpCas9	positive selection	3729104
4118781	4118804	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGTGGTCCCAGGGCTACAGGG	GLIS3	ENSG00000107249	0.3260617409677866	[4]	[5,5]	8	hSpCas9	positive selection	3729105
4118175	4118198	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCAAGACCGAACGCCTGGAGG	GLIS3	ENSG00000107249	0.16856098108572964	[5]	[6,5]	4	hSpCas9	positive selection	3729106
4125777	4125800	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCAGTCCTAGCTTACAGAGGG	GLIS3	ENSG00000107249	-0.1829741757955405	[5]	[2,5]	-3	hSpCas9	positive selection	3837708
4118205	4118228	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCGGGCCCCGACAGCCAGTCGG	GLIS3	ENSG00000107249	-0.11589741398490926	[5]	[3,4]	-2	hSpCas9	positive selection	3837709
4125812	4125835	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGAGACCTGGCTTGCTGGAGG	GLIS3	ENSG00000107249	-1.765689539874141	[4]	[0,0]	-9	hSpCas9	positive selection	3837710
4125778	4125801	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.05202086910960868	[6]	[5,5]	1	hSpCas9	positive selection	3837711
4118781	4118804	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGTGGTCCCAGGGCTACAGGG	GLIS3	ENSG00000107249	0.22308507196608163	[4]	[4,5]	6	hSpCas9	positive selection	3837712
4118175	4118198	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCAAGACCGAACGCCTGGAGG	GLIS3	ENSG00000107249	0.12626366705311054	[6]	[6,5]	3	hSpCas9	positive selection	3837713
3937027	3937050	9	+	26780180	A375	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	1.16618813081289	[]	[]	6	hSpCas9	negative selection	3944140
3937171	3937194	9	-	26780180	A375	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	1.30322165544798	[]	[]	7	hSpCas9	negative selection	3944141
4117908	4117931	9	-	26780180	A375	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.410279869131486	[]	[]	1	hSpCas9	negative selection	3944142
4125844	4125867	9	+	26780180	A375	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.70741538677762	[]	[]	2	hSpCas9	negative selection	3944143
4125846	4125869	9	-	26780180	A375	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	1.3835576060484	[]	[]	7	hSpCas9	negative selection	3944144
4118473	4118496	9	-	26780180	A375	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.241121793209247	[]	[]	0	hSpCas9	negative selection	3944145
3937027	3937050	9	+	26780180	HT29	viability (GeCKOv2 library)	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	1.18180899561938	[]	[]	6	hSpCas9	negative selection	4052106
3937171	3937194	9	-	26780180	HT29	viability (GeCKOv2 library)	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.764807122362136	[]	[]	3	hSpCas9	negative selection	4052107
4117908	4117931	9	-	26780180	HT29	viability (GeCKOv2 library)	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.256441090451257	[]	[]	0	hSpCas9	negative selection	4052108
4125844	4125867	9	+	26780180	HT29	viability (GeCKOv2 library)	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	-0.398389166280097	[]	[]	-8	hSpCas9	negative selection	4052109
4125846	4125869	9	-	26780180	HT29	viability (GeCKOv2 library)	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	1.33393960889682	[]	[]	6	hSpCas9	negative selection	4052110
4118473	4118496	9	-	26780180	HT29	viability (GeCKOv2 library)	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.140811924817384	[]	[]	0	hSpCas9	negative selection	4052111
4125778	4125801	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.16189718902088732	[3]	[2,2]	4	hSpCas9	positive selection	4139974
4125899	4125922	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGTGCAAGTCCATTGGAAAAGG	GLIS3	ENSG00000107249	-0.31870582527108005	[2]	[1,0]	-7	hSpCas9	positive selection	4139975
4117908	4117931	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	-0.14089051214532522	[4]	[2,2]	-3	hSpCas9	positive selection	4139976
4125846	4125869	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.05126121193638307	[3]	[2,2]	1	hSpCas9	positive selection	4139977
4125778	4125801	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	-0.19127508668056203	[4]	[3,0,1,0]	-3	hSpCas9	positive selection	4203996
4125899	4125922	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGTGCAAGTCCATTGGAAAAGG	GLIS3	ENSG00000107249	0.1425211436220936	[3]	[2,2,0,0]	1	hSpCas9	positive selection	4203997
4117908	4117931	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.6246600461893691	[3]	[1,0,0,3]	4	hSpCas9	positive selection	4203998
4125846	4125869	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.2632586931133798	[3]	[1,1,0,0]	-4	hSpCas9	positive selection	4203999
4117908	4117931	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	-0.10274110937389808	[2]	[2,0]	-2	hSpCas9	positive selection	4272962
4118473	4118496	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.7032043923421644	[2]	[3,4]	9	hSpCas9	positive selection	4272963
3937027	3937050	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.007576846457313824	[3]	[3,1]	0	hSpCas9	positive selection	4272964
4125846	4125869	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.11492189541148884	[2]	[2,1]	-2	hSpCas9	positive selection	4337225
3937171	3937194	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.10416771872315486	[2]	[2,0]	-2	hSpCas9	positive selection	4337226
4125844	4125867	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.37166235660549696	[3]	[4,3]	7	hSpCas9	positive selection	4337227
4118191	4118213	9	+	27760321	OCIAML3	viability	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	0.8531450068803559	[632,589]	[562,1256]	8	hSpCas9	negative selection	4403917
4118473	4118495	9	-	27760321	OCIAML3	viability	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.406515191161643	[614,531]	[440,790]	5	hSpCas9	negative selection	4403918
4118504	4118526	9	+	27760321	OCIAML3	viability	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	0.5038130652263814	[735,692]	[792,792]	6	hSpCas9	negative selection	4403919
4118579	4118601	9	+	27760321	OCIAML3	viability	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	0.0705578619611903	[626,563]	[511,457]	0	hSpCas9	negative selection	4403920
4118864	4118886	9	+	27760321	OCIAML3	viability	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	-0.1861808624345737	[378,263]	[191,252]	-2	hSpCas9	negative selection	4403921
4118191	4118213	9	+	27760321	OCIAML2	viability	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	0.5948536396856285	[632,589]	[664,855]	7	hSpCas9	negative selection	4487380
4118473	4118495	9	-	27760321	OCIAML2	viability	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.6803245722994984	[614,531]	[690,807]	8	hSpCas9	negative selection	4487381
4118504	4118526	9	+	27760321	OCIAML2	viability	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	0.03216042397577301	[735,692]	[578,607]	0	hSpCas9	negative selection	4487382
4118579	4118601	9	+	27760321	OCIAML2	viability	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	0.38875581919956526	[626,563]	[642,612]	5	hSpCas9	negative selection	4487383
4118864	4118886	9	+	27760321	OCIAML2	viability	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	0.2043830337822921	[378,263]	[259,343]	2	hSpCas9	negative selection	4487384
4118191	4118213	9	+	27760321	MV411	viability	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	0.1780979561087807	[632,589]	[373,580]	1	hSpCas9	negative selection	4570843
4118473	4118495	9	-	27760321	MV411	viability	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.49559340028821347	[614,531]	[488,596]	3	hSpCas9	negative selection	4570844
4118504	4118526	9	+	27760321	MV411	viability	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	-0.6854886029977978	[735,692]	[69,628]	-5	hSpCas9	negative selection	4570845
4118579	4118601	9	+	27760321	MV411	viability	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	0.4885834435555	[626,563]	[527,584]	3	hSpCas9	negative selection	4570846
4118864	4118886	9	+	27760321	MV411	viability	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	-1.0347893450859402	[378,263]	[67,153]	-6	hSpCas9	negative selection	4570847
4118191	4118213	9	+	27760321	HL60	viability	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	0.5489020331293615	[632,589]	[832,622]	6	hSpCas9	negative selection	4654306
4118473	4118495	9	-	27760321	HL60	viability	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.8985176235802157	[614,531]	[1019,712]	8	hSpCas9	negative selection	4654307
4118504	4118526	9	+	27760321	HL60	viability	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	-0.12029857921187836	[735,692]	[616,452]	-1	hSpCas9	negative selection	4654308
4118579	4118601	9	+	27760321	HL60	viability	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	0.23204824650398614	[626,563]	[478,667]	3	hSpCas9	negative selection	4654309
4118864	4118886	9	+	27760321	HL60	viability	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	0.2263465243652574	[378,263]	[294,312]	2	hSpCas9	negative selection	4654310
4118191	4118213	9	+	27760321	HT1080	viability	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	0.5758602507683854	[589,460]	[344,275]	3	hSpCas9	negative selection	4737769
4118473	4118495	9	-	27760321	HT1080	viability	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	1.6814820658242657	[531,414]	[752,442]	8	hSpCas9	negative selection	4737770
4118504	4118526	9	+	27760321	HT1080	viability	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	-0.6002728786402207	[692,540]	[164,158]	-3	hSpCas9	negative selection	4737771
4118579	4118601	9	+	27760321	HT1080	viability	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	-0.1389364327132967	[563,439]	[162,201]	0	hSpCas9	negative selection	4737772
4118864	4118886	9	+	27760321	HT1080	viability	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	0.6184480954751993	[263,205]	[179,103]	3	hSpCas9	negative selection	4737773
4118191	4118213	9	+	27760321	HT29	viability after 7 days	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	0.47542511601581117	[589,460]	[887,708,1203]	7	hSpCas9	negative selection	4821232
4118473	4118495	9	-	27760321	HT29	viability after 7 days	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.3422654300745088	[531,414]	[729,926,654]	5	hSpCas9	negative selection	4821233
4118504	4118526	9	+	27760321	HT29	viability after 7 days	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	-0.0004053079480238475	[692,540]	[886,791,714]	0	hSpCas9	negative selection	4821234
4118579	4118601	9	+	27760321	HT29	viability after 7 days	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	0.2156072711491322	[563,439]	[928,757,590]	3	hSpCas9	negative selection	4821235
4118864	4118886	9	+	27760321	HT29	viability after 7 days	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	-0.1441381962011019	[263,205]	[634,172,69]	-2	hSpCas9	negative selection	4821236
4118191	4118213	9	+	27760321	HT29	viability after 25 days	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	0.6501601907567098	[589,460]	[919,866,1051]	7	hSpCas9	negative selection	4904695
4118473	4118495	9	-	27760321	HT29	viability after 25 days	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.8428900024833237	[531,414]	[1120,1004,751]	8	hSpCas9	negative selection	4904696
4118504	4118526	9	+	27760321	HT29	viability after 25 days	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	0.657158410966297	[692,540]	[1288,741,1312]	7	hSpCas9	negative selection	4904697
4118579	4118601	9	+	27760321	HT29	viability after 25 days	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	-0.030832327252888092	[563,439]	[628,579,459]	0	hSpCas9	negative selection	4904698
4118864	4118886	9	+	27760321	HT29	viability after 25 days	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	0.3002733562804133	[263,205]	[337,314,338]	3	hSpCas9	negative selection	4904699
4118191	4118213	9	+	27760321	HT29	viability after 22 days	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	0.5826179188466847	[589,460]	[903,773,1052]	6	hSpCas9	negative selection	4988158
4118473	4118495	9	-	27760321	HT29	viability after 22 days	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.6413331964863809	[531,414]	[1046,766,740]	7	hSpCas9	negative selection	4988159
4118504	4118526	9	+	27760321	HT29	viability after 22 days	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	0.5319188765724389	[692,540]	[1441,484,1156]	6	hSpCas9	negative selection	4988160
4118579	4118601	9	+	27760321	HT29	viability after 22 days	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	-0.1653757667192467	[563,439]	[612,503,431]	-2	hSpCas9	negative selection	4988161
4118864	4118886	9	+	27760321	HT29	viability after 22 days	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	0.21297063370424146	[263,205]	[412,316,210]	2	hSpCas9	negative selection	4988162
4118191	4118213	9	+	27760321	HT29	viability after 19 days	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	0.6229329105299617	[589,460]	[907,823,1037]	6	hSpCas9	negative selection	5071621
4118473	4118495	9	-	27760321	HT29	viability after 19 days	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.9292617042617775	[531,414]	[940,1178,965]	8	hSpCas9	negative selection	5071622
4118504	4118526	9	+	27760321	HT29	viability after 19 days	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	0.5587772485117918	[692,540]	[1264,829,1045]	5	hSpCas9	negative selection	5071623
4118579	4118601	9	+	27760321	HT29	viability after 19 days	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	-0.3049116733878674	[563,439]	[464,358,565]	-3	hSpCas9	negative selection	5071624
4118864	4118886	9	+	27760321	HT29	viability after 19 days	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	0.07973704791190261	[263,205]	[431,247,190]	0	hSpCas9	negative selection	5071625
4118191	4118213	9	+	27760321	HT29	viability after 16 days	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	0.6144543771599333	[589,460]	[964,727,1017]	7	hSpCas9	negative selection	5155084
4118473	4118495	9	-	27760321	HT29	viability after 16 days	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.5356991305509089	[531,414]	[1010,638,679]	6	hSpCas9	negative selection	5155085
4118504	4118526	9	+	27760321	HT29	viability after 16 days	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	0.40678980882690163	[692,540]	[1041,736,982]	4	hSpCas9	negative selection	5155086
4118579	4118601	9	+	27760321	HT29	viability after 16 days	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	0.3065925007137104	[563,439]	[829,713,551]	3	hSpCas9	negative selection	5155087
4118864	4118886	9	+	27760321	HT29	viability after 16 days	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	0.5277883440211593	[263,205]	[317,467,342]	6	hSpCas9	negative selection	5155088
4118191	4118213	9	+	27760321	HT29	viability after 13 days	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	0.555825571985807	[589,460]	[778,1067,844]	7	hSpCas9	negative selection	5238547
4118473	4118495	9	-	27760321	HT29	viability after 13 days	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.5476668306894921	[531,414]	[741,1106,573]	7	hSpCas9	negative selection	5238548
4118504	4118526	9	+	27760321	HT29	viability after 13 days	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	0.41498855247470445	[692,540]	[1052,928,884]	5	hSpCas9	negative selection	5238549
4118579	4118601	9	+	27760321	HT29	viability after 13 days	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	-0.11149028534008526	[563,439]	[606,557,456]	-1	hSpCas9	negative selection	5238550
4118864	4118886	9	+	27760321	HT29	viability after 13 days	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	0.07985511048355298	[263,205]	[232,300,327]	0	hSpCas9	negative selection	5238551
4118191	4118213	9	+	27760321	HT29	viability after 10 days	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	0.2099938650858899	[589,460]	[944,699,632]	2	hSpCas9	negative selection	5322010
4118473	4118495	9	-	27760321	HT29	viability after 10 days	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.4032753972477965	[531,414]	[478,869,993]	5	hSpCas9	negative selection	5322011
4118504	4118526	9	+	27760321	HT29	viability after 10 days	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	0.086169213089198	[692,540]	[907,772,771]	1	hSpCas9	negative selection	5322012
4118579	4118601	9	+	27760321	HT29	viability after 10 days	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	-0.23963792047263674	[563,439]	[788,506,300]	-3	hSpCas9	negative selection	5322013
4118864	4118886	9	+	27760321	HT29	viability after 10 days	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	0.5565897386476628	[263,205]	[296,580,420]	7	hSpCas9	negative selection	5322014
4118191	4118213	9	+	27760321	MOLM13	viability	CTTGAACAGGCCGGCCGACTGG	GLIS3	ENSG00000107249	1.2275406781670217	[632,589]	[1107,552]	8	hSpCas9	negative selection	5405473
4118473	4118495	9	-	27760321	MOLM13	viability	GGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.8218533493723847	[614,531]	[772,397]	6	hSpCas9	negative selection	5405474
4118504	4118526	9	+	27760321	MOLM13	viability	GTGGGCGACGTGCGGATGATGG	GLIS3	ENSG00000107249	0.7099750879064014	[735,692]	[774,561]	5	hSpCas9	negative selection	5405475
4118579	4118601	9	+	27760321	MOLM13	viability	TTCTTGGAGCGGGCCGAGTGGG	GLIS3	ENSG00000107249	0.3189079174023016	[626,563]	[651,219]	2	hSpCas9	negative selection	5405476
4118864	4118886	9	+	27760321	MOLM13	viability	TCACGCGAAATAAGGGACCTGG	GLIS3	ENSG00000107249	0.24467110780742066	[378,263]	[333,108]	1	hSpCas9	negative selection	5405477
4117908	4117931	9	-	27260156	BXPC3	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.3120296515187192	[210]	[255,272,308,255]	6	hSpCas9	negative selection	5545422
4118473	4118496	9	-	27260156	BXPC3	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.5643212810110589	[417]	[654,575,688,666]	9	hSpCas9	negative selection	5545423
3937027	3937050	9	+	27260156	BXPC3	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.05040265455087528	[569]	[565,452,763,710]	1	hSpCas9	negative selection	5545424
4125846	4125869	9	-	27260156	BXPC3	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.033562070516090725	[326]	[379,272,374,300]	0	hSpCas9	negative selection	5609685
3937171	3937194	9	-	27260156	BXPC3	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.303812054187936	[334]	[367,419,520,425]	6	hSpCas9	negative selection	5609686
4125844	4125867	9	+	27260156	BXPC3	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.1868818539792263	[946]	[986,1176,1160,1196]	4	hSpCas9	negative selection	5609687
4117908	4117931	9	-	27260156	A673	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.46183586157939305	[210]	[417,397,248,336]	9	hSpCas9	negative selection	5666673
4118473	4118496	9	-	27260156	A673	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.2433858218156682	[417]	[757,483,567,586]	6	hSpCas9	negative selection	5666674
3937027	3937050	9	+	27260156	A673	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	-0.08021547232240886	[569]	[648,650,705,577]	-2	hSpCas9	negative selection	5666675
4125846	4125869	9	-	27260156	A673	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.20577607805319986	[326]	[445,362,278,281]	-5	hSpCas9	negative selection	5730936
3937171	3937194	9	-	27260156	A673	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.1799821035690755	[334]	[580,386,450,416]	4	hSpCas9	negative selection	5730937
4125844	4125867	9	+	27260156	A673	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.05551114835846982	[946]	[1217,1174,964,1383]	1	hSpCas9	negative selection	5730938
4117908	4117931	9	-	27260156	A375	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.735023956341921	[210]	[224,522,499,405]	9	hSpCas9	negative selection	5787924
4118473	4118496	9	-	27260156	A375	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.7449224256085667	[417]	[804,1028,749,725]	9	hSpCas9	negative selection	5787925
3937027	3937050	9	+	27260156	A375	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.2545406518227456	[569]	[423,1056,695,1004]	3	hSpCas9	negative selection	5787926
4125846	4125869	9	-	27260156	A375	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.4189577056611178	[326]	[331,318,287,215]	-5	hSpCas9	negative selection	5852187
3937171	3937194	9	-	27260156	A375	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.08834255487003562	[334]	[364,394,286,420]	-1	hSpCas9	negative selection	5852188
4125844	4125867	9	+	27260156	A375	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	-0.06579130746440065	[946]	[924,1177,1107,1030]	-1	hSpCas9	negative selection	5852189
4117908	4117931	9	-	27260156	COLO741	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	-1.0877316318857875	[210]	[110,127,138]	-9	hSpCas9	negative selection	5909175
4118473	4118496	9	-	27260156	COLO741	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.28815158107897537	[417]	[677,652,627]	6	hSpCas9	negative selection	5909176
3937027	3937050	9	+	27260156	COLO741	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	-0.14629164805238812	[569]	[737,731,519]	-3	hSpCas9	negative selection	5909177
4125846	4125869	9	-	27260156	COLO741	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.12295538602240291	[326]	[457,420,482]	2	hSpCas9	negative selection	5973438
3937171	3937194	9	-	27260156	COLO741	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.16992862536094233	[334]	[382,282,467]	-4	hSpCas9	negative selection	5973439
4125844	4125867	9	+	27260156	COLO741	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.1766449503229479	[946]	[1658,1294,1183]	4	hSpCas9	negative selection	5973440
4117908	4117931	9	-	27260156	CAL120	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.45433234254087884	[210]	[388,361,332]	6	hSpCas9	negative selection	6030426
4118473	4118496	9	-	27260156	CAL120	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.2031278045448548	[417]	[691,621,497]	3	hSpCas9	negative selection	6030427
3937027	3937050	9	+	27260156	CAL120	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.3488431397089989	[569]	[1262,501,996]	5	hSpCas9	negative selection	6030428
4125846	4125869	9	-	27260156	CAL120	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.20924442765786078	[326]	[270,386,384]	-3	hSpCas9	negative selection	6094689
3937171	3937194	9	-	27260156	CAL120	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.460613465300391	[334]	[722,377,640]	7	hSpCas9	negative selection	6094690
4125844	4125867	9	+	27260156	CAL120	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.35599804234165133	[946]	[1539,1039,1940]	5	hSpCas9	negative selection	6094691
4117908	4117931	9	-	27260156	CADOES1	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	-0.4840113624659097	[210]	[119,175,159,103]	-7	hSpCas9	negative selection	6151677
4118473	4118496	9	-	27260156	CADOES1	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.6007428203942606	[417]	[544,531,696,583]	8	hSpCas9	negative selection	6151678
3937027	3937050	9	+	27260156	CADOES1	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.1851780845796695	[569]	[711,589,573,531]	3	hSpCas9	negative selection	6151679
4125846	4125869	9	-	27260156	CADOES1	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.06982322917611095	[326]	[265,299,229,365]	-1	hSpCas9	negative selection	6215940
3937171	3937194	9	-	27260156	CADOES1	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.1753256112766312	[334]	[363,304,441,293]	3	hSpCas9	negative selection	6215941
4125844	4125867	9	+	27260156	CADOES1	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.10277522450212628	[946]	[729,972,873,1216]	1	hSpCas9	negative selection	6215942
4117908	4117931	9	-	27260156	EWS502	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	-0.7190470631667478	[210]	[145,130,134,128]	-8	hSpCas9	negative selection	6272928
4118473	4118496	9	-	27260156	EWS502	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.7625486019776964	[417]	[919,721,680,650]	9	hSpCas9	negative selection	6272929
3937027	3937050	9	+	27260156	EWS502	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.03305618113059294	[569]	[566,594,739,571]	0	hSpCas9	negative selection	6272930
4125846	4125869	9	-	27260156	EWS502	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.025198422328017778	[326]	[395,426,227,346]	0	hSpCas9	negative selection	6337191
3937171	3937194	9	-	27260156	EWS502	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.17881739643218153	[334]	[332,355,412,521]	3	hSpCas9	negative selection	6337192
4125844	4125867	9	+	27260156	EWS502	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.3907547550165762	[946]	[1323,1293,1225,1416]	6	hSpCas9	negative selection	6337193
4117908	4117931	9	-	27260156	EW8	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.23413792315529713	[210]	[223,175,154,258]	4	hSpCas9	negative selection	6394179
4118473	4118496	9	-	27260156	EW8	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.3125368212827466	[417]	[529,376,453,326]	6	hSpCas9	negative selection	6394180
3937027	3937050	9	+	27260156	EW8	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.06039799430321796	[569]	[510,598,334,508]	1	hSpCas9	negative selection	6394181
4125846	4125869	9	-	27260156	EW8	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.19567455657526378	[326]	[327,204,162,250]	-4	hSpCas9	negative selection	6458442
3937171	3937194	9	-	27260156	EW8	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.10450832576066926	[334]	[342,234,272,164]	-2	hSpCas9	negative selection	6458443
4125844	4125867	9	+	27260156	EW8	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.32199793075381655	[946]	[1452,938,774,753]	6	hSpCas9	negative selection	6458444
4117908	4117931	9	-	27260156	CORL105	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.755413477481357	[210]	[472,421,398,372]	9	hSpCas9	negative selection	6515430
4118473	4118496	9	-	27260156	CORL105	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.6582623287304328	[417]	[865,752,823,657]	9	hSpCas9	negative selection	6515431
3937027	3937050	9	+	27260156	CORL105	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	-0.002833772858843675	[569]	[552,759,872,504]	0	hSpCas9	negative selection	6515432
4125846	4125869	9	-	27260156	CORL105	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.4469614035024855	[326]	[276,200,378,282]	-7	hSpCas9	negative selection	6579693
3937171	3937194	9	-	27260156	CORL105	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.2720095104013136	[334]	[354,207,305,429]	-5	hSpCas9	negative selection	6579694
4125844	4125867	9	+	27260156	CORL105	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.028221182494020836	[946]	[969,1168,1386,1029]	0	hSpCas9	negative selection	6579695
4117908	4117931	9	-	27260156	HS294T	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.7921819778917303	[210]	[161,89,162,150]	8	hSpCas9	negative selection	6636681
4118473	4118496	9	-	27260156	HS294T	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.308298660405574	[417]	[225,159,145,279]	4	hSpCas9	negative selection	6636682
3937027	3937050	9	+	27260156	HS294T	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.2626314291856679	[569]	[185,194,274,439]	3	hSpCas9	negative selection	6636683
4125846	4125869	9	-	27260156	HS294T	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.8681426163228148	[326]	[67,61,73,73]	-8	hSpCas9	negative selection	6700944
3937171	3937194	9	-	27260156	HS294T	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.201681045489238	[334]	[123,166,107,207]	2	hSpCas9	negative selection	6700945
4125844	4125867	9	+	27260156	HS294T	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.44947559128893966	[946]	[385,493,492,663]	6	hSpCas9	negative selection	6700946
4117908	4117931	9	-	27260156	HCC44	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.1645243104717723	[210]	[349,149,301,294]	2	hSpCas9	negative selection	6757932
4118473	4118496	9	-	27260156	HCC44	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.1646393644737688	[417]	[703,484,493,450]	2	hSpCas9	negative selection	6757933
3937027	3937050	9	+	27260156	HCC44	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.20287641648181326	[569]	[980,735,723,546]	3	hSpCas9	negative selection	6757934
4125846	4125869	9	-	27260156	HCC44	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.14498541255899822	[326]	[244,389,396,298]	-2	hSpCas9	negative selection	6822195
3937171	3937194	9	-	27260156	HCC44	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.04442209122236507	[334]	[334,475,300,325]	0	hSpCas9	negative selection	6822196
4125844	4125867	9	+	27260156	HCC44	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.0008693468163947227	[946]	[1000,925,1572,884]	0	hSpCas9	negative selection	6822197
4117908	4117931	9	-	27260156	G402	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	-0.10404973830296926	[210]	[370,239,225,143]	-1	hSpCas9	negative selection	6879183
4118473	4118496	9	-	27260156	G402	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.5049150734023573	[417]	[759,922,669,563]	6	hSpCas9	negative selection	6879184
3937027	3937050	9	+	27260156	G402	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	-0.3219902691926988	[569]	[559,441,504,702]	-4	hSpCas9	negative selection	6879185
4125846	4125869	9	-	27260156	G402	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.7495035588948915	[326]	[224,234,259,226]	-7	hSpCas9	negative selection	6943446
3937171	3937194	9	-	27260156	G402	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.41794486591920754	[334]	[622,99,238,294]	-5	hSpCas9	negative selection	6943447
4125844	4125867	9	+	27260156	G402	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.1741463359641282	[946]	[1393,838,1127,1809]	2	hSpCas9	negative selection	6943448
4117908	4117931	9	-	27260156	L33	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.4740058687202945	[210]	[309,109,191,287]	8	hSpCas9	negative selection	7000434
4118473	4118496	9	-	27260156	L33	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.24329488818653947	[417]	[412,217,322,521]	5	hSpCas9	negative selection	7000435
3937027	3937050	9	+	27260156	L33	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.11740012634589936	[569]	[644,246,402,583]	2	hSpCas9	negative selection	7000436
4125846	4125869	9	-	27260156	L33	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.6697321246667773	[326]	[267,78,93,209]	-9	hSpCas9	negative selection	7064697
3937171	3937194	9	-	27260156	L33	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.11500604098330292	[334]	[243,110,220,371]	-3	hSpCas9	negative selection	7064698
4125844	4125867	9	+	27260156	L33	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.13093749047327674	[946]	[1035,389,714,1022]	3	hSpCas9	negative selection	7064699
4117908	4117931	9	-	27260156	K562	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.6713082563388455	[210]	[382,320,247,252]	8	hSpCas9	negative selection	7121685
4118473	4118496	9	-	27260156	K562	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.688534926891295	[417]	[419,938,518,522]	8	hSpCas9	negative selection	7121686
3937027	3937050	9	+	27260156	K562	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.40437804731779897	[569]	[684,763,710,536]	5	hSpCas9	negative selection	7121687
4125846	4125869	9	-	27260156	K562	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.1953286057207	[326]	[529,189,261,351]	2	hSpCas9	negative selection	7185948
3937171	3937194	9	-	27260156	K562	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.2011675279666626	[334]	[319,382,197,155]	-3	hSpCas9	negative selection	7185949
4125844	4125867	9	+	27260156	K562	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.31166308503330975	[946]	[694,1203,1236,1014]	4	hSpCas9	negative selection	7185950
4117908	4117931	9	-	27260156	HT29	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.5310296731566109	[210]	[389,372,504,230]	8	hSpCas9	negative selection	7242936
4118473	4118496	9	-	27260156	HT29	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.3660686948744011	[417]	[672,782,765,432]	7	hSpCas9	negative selection	7242937
3937027	3937050	9	+	27260156	HT29	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	-0.0019780428919636273	[569]	[879,635,560,694]	0	hSpCas9	negative selection	7242938
4125846	4125869	9	-	27260156	HT29	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.22381940915872256	[326]	[478,335,255,302]	-4	hSpCas9	negative selection	7307199
3937171	3937194	9	-	27260156	HT29	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.11382769141312721	[334]	[392,646,476,276]	2	hSpCas9	negative selection	7307200
4125844	4125867	9	+	27260156	HT29	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.35188139914419203	[946]	[1741,1495,1269,1390]	7	hSpCas9	negative selection	7307201
4117908	4117931	9	-	27260156	MHHES1	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.4037045388293061	[210]	[399,269,378,227]	7	hSpCas9	negative selection	7364187
4118473	4118496	9	-	27260156	MHHES1	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.37423745468656366	[417]	[549,829,634,461]	6	hSpCas9	negative selection	7364188
3937027	3937050	9	+	27260156	MHHES1	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	-0.22153998456133384	[569]	[592,455,538,587]	-4	hSpCas9	negative selection	7364189
4125846	4125869	9	-	27260156	MHHES1	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.3183407176051553	[326]	[281,280,135,964]	6	hSpCas9	negative selection	7428450
3937171	3937194	9	-	27260156	MHHES1	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.012549961194446846	[334]	[455,534,358,203]	0	hSpCas9	negative selection	7428451
4125844	4125867	9	+	27260156	MHHES1	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.19853673762718693	[946]	[1525,1469,992,992]	3	hSpCas9	negative selection	7428452
4117908	4117931	9	-	27260156	MEWO	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.08387363966907935	[210]	[202,292,129]	1	hSpCas9	negative selection	7485438
4118473	4118496	9	-	27260156	MEWO	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.31248115540371096	[417]	[706,423,368]	6	hSpCas9	negative selection	7485439
3937027	3937050	9	+	27260156	MEWO	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.0937000527852972	[569]	[633,490,594]	2	hSpCas9	negative selection	7485440
4125846	4125869	9	-	27260156	MEWO	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.16921133247243203	[326]	[252,365,192]	-4	hSpCas9	negative selection	7549701
3937171	3937194	9	-	27260156	MEWO	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.2239637939186827	[334]	[348,187,283]	-5	hSpCas9	negative selection	7549702
4125844	4125867	9	+	27260156	MEWO	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.20689790956583498	[946]	[1116,992,975]	4	hSpCas9	negative selection	7549703
4117908	4117931	9	-	27260156	LNCAPCLONEFGC	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	-0.3610607730641655	[210]	[123,166,192,116]	-5	hSpCas9	negative selection	7606689
4118473	4118496	9	-	27260156	LNCAPCLONEFGC	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.5916807689632989	[417]	[468,572,678,578]	8	hSpCas9	negative selection	7606690
3937027	3937050	9	+	27260156	LNCAPCLONEFGC	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.22506309423596876	[569]	[481,539,736,680]	3	hSpCas9	negative selection	7606691
4125846	4125869	9	-	27260156	LNCAPCLONEFGC	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.08309213704742047	[326]	[353,232,303,366]	1	hSpCas9	negative selection	7670952
3937171	3937194	9	-	27260156	LNCAPCLONEFGC	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.16498287377511112	[334]	[298,385,471,220]	2	hSpCas9	negative selection	7670953
4125844	4125867	9	+	27260156	LNCAPCLONEFGC	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.2604522364115407	[946]	[1085,859,1151,1039]	4	hSpCas9	negative selection	7670954
4117908	4117931	9	-	27260156	PANC0327	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.9037596152945409	[210]	[218,564,261,317]	9	hSpCas9	negative selection	7727940
4118473	4118496	9	-	27260156	PANC0327	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.29156841454289206	[417]	[659,311,441,438]	4	hSpCas9	negative selection	7727941
3937027	3937050	9	+	27260156	PANC0327	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.019323982662280415	[569]	[817,323,530,428]	0	hSpCas9	negative selection	7727942
4125846	4125869	9	-	27260156	PANC0327	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.7534378493877706	[326]	[377,502,630,435]	9	hSpCas9	negative selection	7792203
3937171	3937194	9	-	27260156	PANC0327	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.19348293897808272	[334]	[233,450,306,345]	3	hSpCas9	negative selection	7792204
4125844	4125867	9	+	27260156	PANC0327	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.2025511666053985	[946]	[1243,992,1217,436]	3	hSpCas9	negative selection	7792205
4117908	4117931	9	-	27260156	NCIH2009	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.5030402521118627	[210]	[448,187,625]	7	hSpCas9	negative selection	7849191
4118473	4118496	9	-	27260156	NCIH2009	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.3166311042998785	[417]	[955,615,655]	4	hSpCas9	negative selection	7849192
3937027	3937050	9	+	27260156	NCIH2009	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.5904533132711394	[569]	[1401,1112,1121]	7	hSpCas9	negative selection	7849193
4125846	4125869	9	-	27260156	NCIH2009	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.050547644144352866	[326]	[650,518,282]	0	hSpCas9	negative selection	7913454
3937171	3937194	9	-	27260156	NCIH2009	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.029223168062117222	[334]	[557,529,358]	0	hSpCas9	negative selection	7913455
4125844	4125867	9	+	27260156	NCIH2009	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.22390354154323622	[946]	[1610,1605,1427]	3	hSpCas9	negative selection	7913456
4117908	4117931	9	-	27260156	NCIH1373	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.4899218249046524	[210]	[230,291,461,85]	5	hSpCas9	negative selection	7970442
4118473	4118496	9	-	27260156	NCIH1373	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.6195862220787189	[417]	[1031,638,528,193]	6	hSpCas9	negative selection	7970443
3937027	3937050	9	+	27260156	NCIH1373	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.7211871919734909	[569]	[913,1152,1070,271]	7	hSpCas9	negative selection	7970444
4125846	4125869	9	-	27260156	NCIH1373	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.7060012828392825	[326]	[251,157,248,65]	-6	hSpCas9	negative selection	8034705
3937171	3937194	9	-	27260156	NCIH1373	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.3328400023781548	[334]	[616,151,248,61]	-3	hSpCas9	negative selection	8034706
4125844	4125867	9	+	27260156	NCIH1373	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.5055042502276468	[946]	[1438,1392,1814,356]	5	hSpCas9	negative selection	8034707
4117908	4117931	9	-	27260156	PATU8902	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.6957898467480139	[210]	[433,574,456,434]	7	hSpCas9	negative selection	8091693
4118473	4118496	9	-	27260156	PATU8902	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.6489628176035438	[417]	[1301,833,751,775]	6	hSpCas9	negative selection	8091694
3937027	3937050	9	+	27260156	PATU8902	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.9112973498800854	[569]	[1702,2034,1341,839]	8	hSpCas9	negative selection	8091695
4125846	4125869	9	-	27260156	PATU8902	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.128215103803001	[326]	[658,160,526,646]	1	hSpCas9	negative selection	8155956
3937171	3937194	9	-	27260156	PATU8902	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.00841977848658615	[334]	[301,468,188,1058]	0	hSpCas9	negative selection	8155957
4125844	4125867	9	+	27260156	PATU8902	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.3153819530536246	[946]	[1575,1404,1201,2596]	3	hSpCas9	negative selection	8155958
4117908	4117931	9	-	27260156	PANC1	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	-0.09073459861732536	[210]	[179,186,203,118]	-1	hSpCas9	negative selection	8212944
4118473	4118496	9	-	27260156	PANC1	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.39084716140603337	[417]	[580,547,485,301]	6	hSpCas9	negative selection	8212945
3937027	3937050	9	+	27260156	PANC1	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.24175808898123036	[569]	[417,670,667,572]	4	hSpCas9	negative selection	8212946
4125846	4125869	9	-	27260156	PANC1	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.01468665821318449	[326]	[301,260,273,267]	0	hSpCas9	negative selection	8277207
3937171	3937194	9	-	27260156	PANC1	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.056270198860658927	[334]	[297,395,224,292]	0	hSpCas9	negative selection	8277208
4125844	4125867	9	+	27260156	PANC1	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.30775566822399125	[946]	[950,1168,923,1000]	5	hSpCas9	negative selection	8277209
4117908	4117931	9	-	27260156	PANC0813	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.946074867875988	[210]	[260,584,572,470]	9	hSpCas9	negative selection	8334195
4118473	4118496	9	-	27260156	PANC0813	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	-0.10532882437894842	[417]	[588,415,377,453]	-2	hSpCas9	negative selection	8334196
3937027	3937050	9	+	27260156	PANC0813	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.19561610904723548	[569]	[875,637,775,784]	3	hSpCas9	negative selection	8334197
4125846	4125869	9	-	27260156	PANC0813	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.99853333821241	[326]	[150,248,56,300]	-8	hSpCas9	negative selection	8398458
3937171	3937194	9	-	27260156	PANC0813	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.028299279477702277	[334]	[323,403,521,292]	0	hSpCas9	negative selection	8398459
4125844	4125867	9	+	27260156	PANC0813	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.25665649687975267	[946]	[1425,1375,1105,1408]	4	hSpCas9	negative selection	8398460
4117908	4117931	9	-	27260156	RDES	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.27329723777283443	[210]	[225,250,372,343]	4	hSpCas9	negative selection	8455446
4118473	4118496	9	-	27260156	RDES	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.7290414170906198	[417]	[709,784,693,1022]	9	hSpCas9	negative selection	8455447
3937027	3937050	9	+	27260156	RDES	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.29927553747611607	[569]	[635,790,951,877]	5	hSpCas9	negative selection	8455448
4125846	4125869	9	-	27260156	RDES	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.04265008034097251	[326]	[297,312,424,447]	0	hSpCas9	negative selection	8519709
3937171	3937194	9	-	27260156	RDES	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.2673291560617476	[334]	[319,448,518,610]	4	hSpCas9	negative selection	8519710
4125844	4125867	9	+	27260156	RDES	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.40597458749968207	[946]	[1163,1348,1603,1730]	6	hSpCas9	negative selection	8519711
4117908	4117931	9	-	27260156	PC3	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	-0.012902621216991372	[210]	[61,169,635,187]	0	hSpCas9	negative selection	8576697
4118473	4118496	9	-	27260156	PC3	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.11076238913301997	[417]	[330,432,700,433]	2	hSpCas9	negative selection	8576698
3937027	3937050	9	+	27260156	PC3	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.025841862215708333	[569]	[361,593,783,695]	0	hSpCas9	negative selection	8576699
4125846	4125869	9	-	27260156	PC3	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.04464086106453574	[326]	[205,209,820,329]	1	hSpCas9	negative selection	8640960
3937171	3937194	9	-	27260156	PC3	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.27717926109354296	[334]	[306,404,420,490]	6	hSpCas9	negative selection	8640961
4125844	4125867	9	+	27260156	PC3	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.14221569908338072	[946]	[719,919,1763,1083]	3	hSpCas9	negative selection	8640962
4117908	4117931	9	-	27260156	PATU8988T	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.36036462754666587	[210]	[84,293,376,294]	6	hSpCas9	negative selection	8697948
4118473	4118496	9	-	27260156	PATU8988T	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.17991101560176712	[417]	[426,547,448,410]	3	hSpCas9	negative selection	8697949
3937027	3937050	9	+	27260156	PATU8988T	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.006250255414303574	[569]	[517,854,465,389]	0	hSpCas9	negative selection	8697950
4125846	4125869	9	-	27260156	PATU8988T	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.11620941916735583	[326]	[342,179,329,302]	-2	hSpCas9	negative selection	8762211
3937171	3937194	9	-	27260156	PATU8988T	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.5263666609079596	[334]	[580,433,430,411]	8	hSpCas9	negative selection	8762212
4125844	4125867	9	+	27260156	PATU8988T	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.25919961488286836	[946]	[923,1134,1075,1262]	4	hSpCas9	negative selection	8762213
4117908	4117931	9	-	27260156	T47D	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.42705551402214925	[210]	[312,308,309,393]	8	hSpCas9	negative selection	8819199
4118473	4118496	9	-	27260156	T47D	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.44900242108722	[417]	[692,531,751,692]	8	hSpCas9	negative selection	8819200
3937027	3937050	9	+	27260156	T47D	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.025205503938630025	[569]	[616,611,741,737]	0	hSpCas9	negative selection	8819201
4125846	4125869	9	-	27260156	T47D	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.056535949022754106	[326]	[327,405,381,469]	1	hSpCas9	negative selection	8883462
3937171	3937194	9	-	27260156	T47D	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.2836437848636353	[334]	[561,462,435,439]	6	hSpCas9	negative selection	8883463
4125844	4125867	9	+	27260156	T47D	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.12921272809069984	[946]	[1099,1218,1176,1332]	2	hSpCas9	negative selection	8883464
4117908	4117931	9	-	27260156	SU8686	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.6831899341067682	[210]	[319,343,198,501]	9	hSpCas9	negative selection	8940450
4118473	4118496	9	-	27260156	SU8686	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.5481239242664584	[417]	[605,587,441,814]	8	hSpCas9	negative selection	8940451
3937027	3937050	9	+	27260156	SU8686	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.1952893787653584	[569]	[654,737,564,602]	3	hSpCas9	negative selection	8940452
4125846	4125869	9	-	27260156	SU8686	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.08207350986143513	[326]	[264,193,363,442]	-1	hSpCas9	negative selection	9004713
3937171	3937194	9	-	27260156	SU8686	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.0497076568168936	[334]	[253,275,298,492]	-1	hSpCas9	negative selection	9004714
4125844	4125867	9	+	27260156	SU8686	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.20371861556286586	[946]	[1072,917,1281,1069]	3	hSpCas9	negative selection	9004715
4117908	4117931	9	-	27260156	SKES1	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.05454325888698652	[210]	[162,298,179,230]	1	hSpCas9	negative selection	9061701
4118473	4118496	9	-	27260156	SKES1	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.40579169472761	[417]	[566,511,551,567]	8	hSpCas9	negative selection	9061702
3937027	3937050	9	+	27260156	SKES1	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.2548725667878861	[569]	[660,783,635,640]	5	hSpCas9	negative selection	9061703
4125846	4125869	9	-	27260156	SKES1	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.6183422366090146	[326]	[110,277,175,269]	-8	hSpCas9	negative selection	9125964
3937171	3937194	9	-	27260156	SKES1	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	-0.22829670125914836	[334]	[296,357,235,260]	-5	hSpCas9	negative selection	9125965
4125844	4125867	9	+	27260156	SKES1	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.07368840729834858	[946]	[1216,1198,681,934]	1	hSpCas9	negative selection	9125966
4117908	4117931	9	-	27260156	TOV112D	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	-0.25584573248367515	[210]	[156,248,151,165]	-5	hSpCas9	negative selection	9182952
4118473	4118496	9	-	27260156	TOV112D	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.2649700858612549	[417]	[347,662,498,526]	5	hSpCas9	negative selection	9182953
3937027	3937050	9	+	27260156	TOV112D	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.1170869775858015	[569]	[564,611,627,662]	2	hSpCas9	negative selection	9182954
4125846	4125869	9	-	27260156	TOV112D	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	0.005514993398029078	[326]	[300,345,470,201]	0	hSpCas9	negative selection	9247215
3937171	3937194	9	-	27260156	TOV112D	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.29920893440208685	[334]	[531,536,343,281]	6	hSpCas9	negative selection	9247216
4125844	4125867	9	+	27260156	TOV112D	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.16410066137899837	[946]	[1155,1120,1172,827]	3	hSpCas9	negative selection	9247217
4117908	4117931	9	-	27260156	TC71	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.03613045469006315	[210]	[254,155,306,204]	0	hSpCas9	negative selection	9304203
4118473	4118496	9	-	27260156	TC71	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.11586967901618297	[417]	[573,426,495,439]	3	hSpCas9	negative selection	9304204
3937027	3937050	9	+	27260156	TC71	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.04143378762863881	[569]	[713,528,599,673]	1	hSpCas9	negative selection	9304205
4125846	4125869	9	-	27260156	TC71	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.042384260953839736	[326]	[361,303,279,421]	-1	hSpCas9	negative selection	9368466
3937171	3937194	9	-	27260156	TC71	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.3439004289475791	[334]	[423,587,377,434]	7	hSpCas9	negative selection	9368467
4125844	4125867	9	+	27260156	TC71	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.14596764759742076	[946]	[984,1167,1084,1267]	3	hSpCas9	negative selection	9368468
4117908	4117931	9	-	27260156	TC32	viability	GCTCGTGCGGCACATCGAGAAGG	GLIS3	ENSG00000107249	0.21073101701800268	[210]	[283,141,326,191]	4	hSpCas9	negative selection	9425454
4118473	4118496	9	-	27260156	TC32	viability	TGGCCTACATCAACGGGTCGAGG	GLIS3	ENSG00000107249	0.4957097791114262	[417]	[460,457,743,602]	8	hSpCas9	negative selection	9425455
3937027	3937050	9	+	27260156	TC32	viability	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.31839800390874345	[569]	[641,519,693,848]	5	hSpCas9	negative selection	9425456
4125846	4125869	9	-	27260156	TC32	viability	TCCCATGATGGTTCAGCGACTGG	GLIS3	ENSG00000107249	-0.14727429597798625	[326]	[251,182,472,257]	-3	hSpCas9	negative selection	9489717
3937171	3937194	9	-	27260156	TC32	viability	GCAGTTTGAAGGTTGCGAGAAGG	GLIS3	ENSG00000107249	0.055274022706706505	[334]	[337,158,359,511]	1	hSpCas9	negative selection	9489718
4125844	4125867	9	+	27260156	TC32	viability	TCCCAGTCGCTGAACCATCATGG	GLIS3	ENSG00000107249	0.34711761776753236	[946]	[954,970,1675,1028]	6	hSpCas9	negative selection	9489719
3829314	3829337	9	+	27869803	HPAFII	viability after 27 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	0.9078711992002281	[133]	[267,18,NaN]	7	hSpCas9	negative selection	9606146
3937027	3937050	9	+	27869803	HPAFII	viability after 27 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	1.1806758361782295	[191]	[314,156,NaN]	8	hSpCas9	negative selection	9606161
4118789	4118812	9	-	27869803	HPAFII	viability after 27 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	1.4475440072613368	[118]	[144,191,NaN]	9	hSpCas9	negative selection	9606162
4125778	4125801	9	-	27869803	HPAFII	viability after 27 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	1.4210660476809216	[363]	[458,556,NaN]	9	hSpCas9	negative selection	9606163
4286229	4286252	9	-	27869803	HPAFII	viability after 27 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	-0.10592534884001359	[98]	[25,66,NaN]	-1	hSpCas9	negative selection	9606164
3829314	3829337	9	+	27869803	HPAFII	viability after 15 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	0.027387684142775814	[133]	[221,99,NaN]	0	hSpCas9	negative selection	9688595
3937027	3937050	9	+	27869803	HPAFII	viability after 15 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.3045067469323396	[191]	[490,107,NaN]	3	hSpCas9	negative selection	9688610
4118789	4118812	9	-	27869803	HPAFII	viability after 15 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	0.7625947288372035	[118]	[306,160,NaN]	8	hSpCas9	negative selection	9688611
4125778	4125801	9	-	27869803	HPAFII	viability after 15 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.6361543971636305	[363]	[763,510,NaN]	7	hSpCas9	negative selection	9688612
4286229	4286252	9	-	27869803	HPAFII	viability after 15 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	-0.28921596133639116	[98]	[128,60,NaN]	-3	hSpCas9	negative selection	9688613
3829314	3829337	9	+	27869803	ASPC1	viability after 36 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	-0.5444666703574939	[306]	[167,44,28]	-5	hSpCas9	negative selection	9771044
3937027	3937050	9	+	27869803	ASPC1	viability after 36 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	0.07531063416527045	[498]	[286,180,110]	0	hSpCas9	negative selection	9771059
4118789	4118812	9	-	27869803	ASPC1	viability after 36 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	0.770909509152909	[288]	[299,148,98]	7	hSpCas9	negative selection	9771060
4125778	4125801	9	-	27869803	ASPC1	viability after 36 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.3000949591229196	[1058]	[754,240,409]	3	hSpCas9	negative selection	9771061
4286229	4286252	9	-	27869803	ASPC1	viability after 36 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.3250262673597403	[258]	[135,159,58]	3	hSpCas9	negative selection	9771062
3829314	3829337	9	+	27869803	PATU8988S	viability after 35 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	0.30620916262050313	[266]	[115,149,NaN]	3	hSpCas9	negative selection	9853493
3937027	3937050	9	+	27869803	PATU8988S	viability after 35 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	1.1059585812468204	[283]	[331,159,NaN]	9	hSpCas9	negative selection	9853508
4118789	4118812	9	-	27869803	PATU8988S	viability after 35 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	0.2930434930100606	[303]	[154,144,NaN]	3	hSpCas9	negative selection	9853509
4125778	4125801	9	-	27869803	PATU8988S	viability after 35 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.32717534262055425	[759]	[386,380,NaN]	4	hSpCas9	negative selection	9853510
4286229	4286252	9	-	27869803	PATU8988S	viability after 35 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.12630465102294575	[189]	[93,72,NaN]	1	hSpCas9	negative selection	9853511
3829314	3829337	9	+	27869803	PATU8988S	viability after 31 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	0.4764619282467326	[266]	[181,104,NaN]	6	hSpCas9	negative selection	9935942
3937027	3937050	9	+	27869803	PATU8988S	viability after 31 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	1.1040882089719048	[283]	[198,299,NaN]	9	hSpCas9	negative selection	9935957
4118789	4118812	9	-	27869803	PATU8988S	viability after 31 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	-0.5093393748360745	[303]	[89,78,NaN]	-5	hSpCas9	negative selection	9935958
4125778	4125801	9	-	27869803	PATU8988S	viability after 31 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	0.22226590169844718	[759]	[360,343,NaN]	2	hSpCas9	negative selection	9935959
4286229	4286252	9	-	27869803	PATU8988S	viability after 31 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	-0.10260790655437035	[189]	[70,69,NaN]	-1	hSpCas9	negative selection	9935960
3829314	3829337	9	+	27869803	HPAFII	viability after 35 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	1.1611480564912973	[133]	[273,13,NaN]	7	hSpCas9	negative selection	10018391
3937027	3937050	9	+	27869803	HPAFII	viability after 35 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	2.228051419560682	[191]	[508,394,NaN]	9	hSpCas9	negative selection	10018406
4118789	4118812	9	-	27869803	HPAFII	viability after 35 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	2.04741012128462	[118]	[177,328,NaN]	9	hSpCas9	negative selection	10018407
4125778	4125801	9	-	27869803	HPAFII	viability after 35 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	1.7263515895876074	[363]	[565,658,NaN]	9	hSpCas9	negative selection	10018408
4286229	4286252	9	-	27869803	HPAFII	viability after 35 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.2013425037663903	[98]	[11,108,NaN]	1	hSpCas9	negative selection	10018409
3829314	3829337	9	+	27869803	HPAFII	viability after 31 days	AATGCCCGAGTGAGTCGAGAAGG	GLIS3	ENSG00000107249	0.8545932989113126	[133]	[224,38,NaN]	6	hSpCas9	negative selection	10100840
3937027	3937050	9	+	27869803	HPAFII	viability after 31 days	CGGTGTCCAGATGCGTCCGCTGG	GLIS3	ENSG00000107249	1.5288149387573957	[191]	[364,251,NaN]	9	hSpCas9	negative selection	10100855
4118789	4118812	9	-	27869803	HPAFII	viability after 31 days	ATGAAGCAGGAGTGGTCCCAGGG	GLIS3	ENSG00000107249	1.6827145319377241	[118]	[200,228,NaN]	9	hSpCas9	negative selection	10100856
4125778	4125801	9	-	27869803	HPAFII	viability after 31 days	AGATCAGTCCTAGCTTACAGAGG	GLIS3	ENSG00000107249	1.5367348067568112	[363]	[585,599,NaN]	9	hSpCas9	negative selection	10100857
4286229	4286252	9	-	27869803	HPAFII	viability after 31 days	CATCTCAAGATGCCCTCAGGAGG	GLIS3	ENSG00000107249	0.14669663560471102	[98]	[16,109,NaN]	1	hSpCas9	negative selection	10100858
4118758	4118781	9	+	28162770	P31FUJ	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	-0.49266933116948947	[181]	[151]	-4	hSpCas9	negative selection	10162665
3829408	3829431	9	+	28162770	P31FUJ	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	1.0249955530532682	[22]	[54]	9	hSpCas9	negative selection	10162666
3879453	3879476	9	+	28162770	P31FUJ	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-1.0134891760099027	[200]	[116]	-6	hSpCas9	negative selection	10162667
4118600	4118623	9	+	28162770	P31FUJ	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	0.5389288079125043	[40]	[69]	6	hSpCas9	negative selection	10162668
4118241	4118264	9	-	28162770	P31FUJ	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	-0.04278578503259736	[205]	[234]	0	hSpCas9	negative selection	10162669
3937058	3937081	9	+	28162770	P31FUJ	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	-0.0812197830938689	[342]	[380]	-1	hSpCas9	negative selection	10162670
3937043	3937066	9	-	28162770	P31FUJ	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	0.36923380966571906	[335]	[509]	4	hSpCas9	negative selection	10162671
3879511	3879534	9	+	28162770	P31FUJ	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	0.1873421852975541	[422]	[565]	2	hSpCas9	negative selection	10162672
3856125	3856148	9	+	28162770	P31FUJ	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	0.3343941784981972	[462]	[685]	3	hSpCas9	negative selection	10162673
4118758	4118781	9	+	28162770	TF1	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10332031
3829408	3829431	9	+	28162770	TF1	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10332032
3879453	3879476	9	+	28162770	TF1	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10332033
4118600	4118623	9	+	28162770	TF1	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10332034
4118241	4118264	9	-	28162770	TF1	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	NaN	[NaN]	[201]	1	hSpCas9	negative selection	10332035
3937058	3937081	9	+	28162770	TF1	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	NaN	[NaN]	[162]	1	hSpCas9	negative selection	10332036
3937043	3937066	9	-	28162770	TF1	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10332037
3879511	3879534	9	+	28162770	TF1	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	NaN	[NaN]	[478]	1	hSpCas9	negative selection	10332038
3856125	3856148	9	+	28162770	TF1	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	NaN	[NaN]	[314]	1	hSpCas9	negative selection	10332039
4118758	4118781	9	+	28162770	SKM1	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	0.832862815929307	[46]	[147]	7	hSpCas9	negative selection	10501397
3829408	3829431	9	+	28162770	SKM1	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	-1.3525164147207853	[12]	[8]	-7	hSpCas9	negative selection	10501398
3879453	3879476	9	+	28162770	SKM1	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-0.1578689838672417	[64]	[102]	-1	hSpCas9	negative selection	10501399
4118600	4118623	9	+	28162770	SKM1	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	0.6286597109875598	[14]	[40]	6	hSpCas9	negative selection	10501400
4118241	4118264	9	-	28162770	SKM1	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	-0.3783950465463907	[74]	[101]	-3	hSpCas9	negative selection	10501401
3937058	3937081	9	+	28162770	SKM1	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	-0.07575829026778869	[92]	[155]	0	hSpCas9	negative selection	10501402
3937043	3937066	9	-	28162770	SKM1	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	-0.13550117083878702	[63]	[102]	-1	hSpCas9	negative selection	10501403
3879511	3879534	9	+	28162770	SKM1	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	0.5197868192261998	[100]	[255]	5	hSpCas9	negative selection	10501404
3856125	3856148	9	+	28162770	SKM1	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	0.5343898064335784	[90]	[232]	5	hSpCas9	negative selection	10501405
4118758	4118781	9	+	28162770	SKM1	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	0.832862815929307	[46]	[147]	7	hSpCas9	negative selection	10670763
3829408	3829431	9	+	28162770	SKM1	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	-1.3525164147207853	[12]	[8]	-7	hSpCas9	negative selection	10670764
3879453	3879476	9	+	28162770	SKM1	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-0.1578689838672417	[64]	[102]	-1	hSpCas9	negative selection	10670765
4118600	4118623	9	+	28162770	SKM1	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	0.6286597109875598	[14]	[40]	6	hSpCas9	negative selection	10670766
4118241	4118264	9	-	28162770	SKM1	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	-0.3783950465463907	[74]	[101]	-3	hSpCas9	negative selection	10670767
3937058	3937081	9	+	28162770	SKM1	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	-0.07575829026778869	[92]	[155]	0	hSpCas9	negative selection	10670768
3937043	3937066	9	-	28162770	SKM1	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	-0.13550117083878702	[63]	[102]	-1	hSpCas9	negative selection	10670769
3879511	3879534	9	+	28162770	SKM1	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	0.5197868192261998	[100]	[255]	5	hSpCas9	negative selection	10670770
3856125	3856148	9	+	28162770	SKM1	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	0.5343898064335784	[90]	[232]	5	hSpCas9	negative selection	10670771
4118758	4118781	9	+	28162770	PL21	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	-1.9797694755256146	[289]	[31]	-8	hSpCas9	negative selection	10840129
3829408	3829431	9	+	28162770	PL21	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	-1.8354842952414012	[40]	[4]	-8	hSpCas9	negative selection	10840130
3879453	3879476	9	+	28162770	PL21	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-0.4392706702542124	[242]	[77]	-3	hSpCas9	negative selection	10840131
4118600	4118623	9	+	28162770	PL21	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	-0.5588522860068847	[43]	[12]	-4	hSpCas9	negative selection	10840132
4118241	4118264	9	-	28162770	PL21	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	0.6612735283576179	[230]	[158]	6	hSpCas9	negative selection	10840133
3937058	3937081	9	+	28162770	PL21	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	0.47851456645759993	[342]	[207]	4	hSpCas9	negative selection	10840134
3937043	3937066	9	-	28162770	PL21	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	0.8639976603822568	[254]	[201]	7	hSpCas9	negative selection	10840135
3879511	3879534	9	+	28162770	PL21	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	0.48177123920044407	[333]	[202]	4	hSpCas9	negative selection	10840136
3856125	3856148	9	+	28162770	PL21	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	0.620248103315586	[283]	[189]	5	hSpCas9	negative selection	10840137
4118758	4118781	9	+	28162770	P31FUJ	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	-0.49266933116948947	[181]	[151]	-4	hSpCas9	negative selection	11009495
3829408	3829431	9	+	28162770	P31FUJ	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	1.0249955530532682	[22]	[54]	9	hSpCas9	negative selection	11009496
3879453	3879476	9	+	28162770	P31FUJ	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-1.0134891760099027	[200]	[116]	-6	hSpCas9	negative selection	11009497
4118600	4118623	9	+	28162770	P31FUJ	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	0.5389288079125043	[40]	[69]	6	hSpCas9	negative selection	11009498
4118241	4118264	9	-	28162770	P31FUJ	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	-0.04278578503259736	[205]	[234]	0	hSpCas9	negative selection	11009499
3937058	3937081	9	+	28162770	P31FUJ	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	-0.0812197830938689	[342]	[380]	-1	hSpCas9	negative selection	11009500
3937043	3937066	9	-	28162770	P31FUJ	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	0.36923380966571906	[335]	[509]	4	hSpCas9	negative selection	11009501
3879511	3879534	9	+	28162770	P31FUJ	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	0.1873421852975541	[422]	[565]	2	hSpCas9	negative selection	11009502
3856125	3856148	9	+	28162770	P31FUJ	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	0.3343941784981972	[462]	[685]	3	hSpCas9	negative selection	11009503
4118758	4118781	9	+	28162770	OCIAML5	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	0.03289492086978646	[136]	[252]	0	hSpCas9	negative selection	11178861
3829408	3829431	9	+	28162770	OCIAML5	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	-1.437029071585153	[32]	[21]	-7	hSpCas9	negative selection	11178862
3879453	3879476	9	+	28162770	OCIAML5	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	0.09854540217383945	[103]	[200]	0	hSpCas9	negative selection	11178863
4118600	4118623	9	+	28162770	OCIAML5	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	-0.40460759389277556	[32]	[44]	-3	hSpCas9	negative selection	11178864
4118241	4118264	9	-	28162770	OCIAML5	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	0.6085677948549575	[108]	[299]	5	hSpCas9	negative selection	11178865
3937058	3937081	9	+	28162770	OCIAML5	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	0.7673294269210332	[137]	[423]	6	hSpCas9	negative selection	11178866
3937043	3937066	9	-	28162770	OCIAML5	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	0.331155253191773	[143]	[326]	3	hSpCas9	negative selection	11178867
3879511	3879534	9	+	28162770	OCIAML5	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	0.377667825813619	[251]	[590]	3	hSpCas9	negative selection	11178868
3856125	3856148	9	+	28162770	OCIAML5	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	-0.10123832331604521	[289]	[487]	0	hSpCas9	negative selection	11178869
4118758	4118781	9	+	28162770	EOL1	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	-0.8102135516689416	[435]	[130]	-5	hSpCas9	negative selection	11348227
3829408	3829431	9	+	28162770	EOL1	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	0.010277645596418417	[48]	[25]	0	hSpCas9	negative selection	11348228
3879453	3879476	9	+	28162770	EOL1	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-0.1989488941855212	[450]	[206]	-1	hSpCas9	negative selection	11348229
4118600	4118623	9	+	28162770	EOL1	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	-1.633447681550352	[105]	[17]	-7	hSpCas9	negative selection	11348230
4118241	4118264	9	-	28162770	EOL1	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	0.9675248443158098	[462]	[476]	8	hSpCas9	negative selection	11348231
3937058	3937081	9	+	28162770	EOL1	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	-0.5294838593241732	[599]	[218]	-4	hSpCas9	negative selection	11348232
3937043	3937066	9	-	28162770	EOL1	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	0.07264641055966846	[295]	[163]	0	hSpCas9	negative selection	11348233
3879511	3879534	9	+	28162770	EOL1	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	-0.05036124746663506	[455]	[231]	0	hSpCas9	negative selection	11348234
3856125	3856148	9	+	28162770	EOL1	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	0.06331184152638625	[415]	[228]	0	hSpCas9	negative selection	11348235
4118758	4118781	9	+	28162770	MOLM13	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	-0.4229888960753086	[279]	[150]	-3	hSpCas9	negative selection	11517593
3829408	3829431	9	+	28162770	MOLM13	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	-5.414753667817263	[58]	[0]	-9	hSpCas9	negative selection	11517594
3879453	3879476	9	+	28162770	MOLM13	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	0.40666258229413255	[360]	[345]	3	hSpCas9	negative selection	11517595
4118600	4118623	9	+	28162770	MOLM13	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	0.24810817366466886	[91]	[78]	1	hSpCas9	negative selection	11517596
4118241	4118264	9	-	28162770	MOLM13	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	0.5665369694774901	[324]	[347]	4	hSpCas9	negative selection	11517597
3937058	3937081	9	+	28162770	MOLM13	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	1.012568286800387	[459]	[670]	7	hSpCas9	negative selection	11517598
3937043	3937066	9	-	28162770	MOLM13	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	0.4467660899788246	[343]	[338]	3	hSpCas9	negative selection	11517599
3879511	3879534	9	+	28162770	MOLM13	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	0.9614959331975325	[401]	[565]	7	hSpCas9	negative selection	11517600
3856125	3856148	9	+	28162770	MOLM13	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	1.0192211043844548	[433]	[635]	7	hSpCas9	negative selection	11517601
4118758	4118781	9	+	28162770	HEL	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	-1.1162530684958483	[307]	[90]	-6	hSpCas9	negative selection	11686959
3829408	3829431	9	+	28162770	HEL	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	-3.0353330731122803	[63]	[4]	-8	hSpCas9	negative selection	11686960
3879453	3879476	9	+	28162770	HEL	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-1.284825331872911	[368]	[96]	-6	hSpCas9	negative selection	11686961
4118600	4118623	9	+	28162770	HEL	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	-0.02284212892908366	[45]	[28]	0	hSpCas9	negative selection	11686962
4118241	4118264	9	-	28162770	HEL	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	-0.1621308266676527	[289]	[165]	-1	hSpCas9	negative selection	11686963
3937058	3937081	9	+	28162770	HEL	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	-0.4247241357783819	[393]	[187]	-3	hSpCas9	negative selection	11686964
3937043	3937066	9	-	28162770	HEL	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	-3.0249640997287353	[304]	[23]	-8	hSpCas9	negative selection	11686965
3879511	3879534	9	+	28162770	HEL	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	-0.9461281231767154	[369]	[122]	-5	hSpCas9	negative selection	11686966
3856125	3856148	9	+	28162770	HEL	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	-1.0752258002357933	[351]	[106]	-6	hSpCas9	negative selection	11686967
4118758	4118781	9	+	28162770	MV411	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	-0.0371300166006599	[161]	[132]	0	hSpCas9	negative selection	11856325
3829408	3829431	9	+	28162770	MV411	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	1.3955361897719092	[36]	[81]	9	hSpCas9	negative selection	11856326
3879453	3879476	9	+	28162770	MV411	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-0.7578958935202653	[270]	[134]	-5	hSpCas9	negative selection	11856327
4118600	4118623	9	+	28162770	MV411	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	0.8157213103573011	[28]	[42]	7	hSpCas9	negative selection	11856328
4118241	4118264	9	-	28162770	MV411	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	0.987421336511896	[190]	[318]	8	hSpCas9	negative selection	11856329
3937058	3937081	9	+	28162770	MV411	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	1.0348605705185072	[353]	[610]	8	hSpCas9	negative selection	11856330
3937043	3937066	9	-	28162770	MV411	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	0.7770232944675579	[238]	[344]	7	hSpCas9	negative selection	11856331
3879511	3879534	9	+	28162770	MV411	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	1.0492859965338357	[299]	[522]	8	hSpCas9	negative selection	11856332
3856125	3856148	9	+	28162770	MV411	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	0.18765632245735842	[270]	[259]	1	hSpCas9	negative selection	11856333
4118758	4118781	9	+	28162770	MONOMAC1	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	0.019538247681579995	[141]	[164]	0	hSpCas9	negative selection	12025691
3829408	3829431	9	+	28162770	MONOMAC1	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	-0.7116100198893118	[19]	[13]	-5	hSpCas9	negative selection	12025692
3879453	3879476	9	+	28162770	MONOMAC1	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	0.32473182717440846	[139]	[200]	3	hSpCas9	negative selection	12025693
4118600	4118623	9	+	28162770	MONOMAC1	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	0.6826689192227344	[24]	[45]	6	hSpCas9	negative selection	12025694
4118241	4118264	9	-	28162770	MONOMAC1	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	-0.2626251886871304	[179]	[171]	-2	hSpCas9	negative selection	12025695
3937058	3937081	9	+	28162770	MONOMAC1	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	-0.09854698366019038	[183]	[196]	-1	hSpCas9	negative selection	12025696
3937043	3937066	9	-	28162770	MONOMAC1	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	0.47038781385357537	[152]	[242]	4	hSpCas9	negative selection	12025697
3879511	3879534	9	+	28162770	MONOMAC1	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	0.3945587459940495	[216]	[326]	4	hSpCas9	negative selection	12025698
3856125	3856148	9	+	28162770	MONOMAC1	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	0.3175363257702045	[167]	[239]	3	hSpCas9	negative selection	12025699
4118758	4118781	9	+	28162770	OCIAML2	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	-0.26366744447531915	[46]	[216]	-2	hSpCas9	negative selection	12195057
3829408	3829431	9	+	28162770	OCIAML2	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	-1.733664231075955	[8]	[14]	-8	hSpCas9	negative selection	12195058
3879453	3879476	9	+	28162770	OCIAML2	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-0.8331999046268697	[44]	[139]	-5	hSpCas9	negative selection	12195059
4118600	4118623	9	+	28162770	OCIAML2	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	-0.2335906279413118	[6]	[32]	-2	hSpCas9	negative selection	12195060
4118241	4118264	9	-	28162770	OCIAML2	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	0.15645815115167144	[44]	[277]	1	hSpCas9	negative selection	12195061
3937058	3937081	9	+	28162770	OCIAML2	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	0.6248169602408749	[52]	[452]	6	hSpCas9	negative selection	12195062
3937043	3937066	9	-	28162770	OCIAML2	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	-0.051916667819918993	[48]	[261]	0	hSpCas9	negative selection	12195063
3879511	3879534	9	+	28162770	OCIAML2	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	0.8543007578067245	[47]	[480]	8	hSpCas9	negative selection	12195064
3856125	3856148	9	+	28162770	OCIAML2	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	1.3007457997098761	[28]	[395]	9	hSpCas9	negative selection	12195065
4118758	4118781	9	+	28162770	OCIAML3	viability	GTGGTTGGAGAGCGAAGGGAGGG	GLIS3	ENSG00000107249	1.4578312911954547	[40]	[339]	9	hSpCas9	negative selection	12364423
3829408	3829431	9	+	28162770	OCIAML3	viability	ACACTGCAGGAGCTGACAGGCGG	GLIS3	ENSG00000107249	0.9169542789532159	[9]	[56]	7	hSpCas9	negative selection	12364424
3879453	3879476	9	+	28162770	OCIAML3	viability	GAGTGGAGGTAACTGGGAGGAGG	GLIS3	ENSG00000107249	-1.7544723125174093	[75]	[67]	-8	hSpCas9	negative selection	12364425
4118600	4118623	9	+	28162770	OCIAML3	viability	GACCTGGTGGATGAGTGCCGAGG	GLIS3	ENSG00000107249	1.4792413417064756	[11]	[100]	9	hSpCas9	negative selection	12364426
4118241	4118264	9	-	28162770	OCIAML3	viability	AGGCCTGGTCAACCACATGGTGG	GLIS3	ENSG00000107249	0.23254084696675187	[63]	[226]	2	hSpCas9	negative selection	12364427
3937058	3937081	9	+	28162770	OCIAML3	viability	GCGGTCACTGGAGTTACTGAAGG	GLIS3	ENSG00000107249	0.23090565311774575	[69]	[247]	2	hSpCas9	negative selection	12364428
3937043	3937066	9	-	28162770	OCIAML3	viability	GTGACCGCGCCAAACACCAGCGG	GLIS3	ENSG00000107249	0.4618455944093542	[56]	[236]	4	hSpCas9	negative selection	12364429
3879511	3879534	9	+	28162770	OCIAML3	viability	GAAGGGTGACTGACAGGATGTGG	GLIS3	ENSG00000107249	0.41866618971094727	[84]	[342]	4	hSpCas9	negative selection	12364430
3856125	3856148	9	+	28162770	OCIAML3	viability	GAAGGAGCTGGAACTCTCCGGGG	GLIS3	ENSG00000107249	-0.09879979236133596	[104]	[295]	-1	hSpCas9	negative selection	12364431