Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 27429
• Symbol: HtrA2
• Description: HtrA serine peptidase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/HtrA2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
74529417	74529440	2	+	26472758	Jiyoye	viability	GAAAGAGGCGCAGGACGAGGAGG	HTRA2	ENSG00000115317	-1.8241501646005822	[215]	[45]	-8	hSpCas9	negative selection	13064
74530468	74530491	2	+	26472758	Jiyoye	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	0.9067463909963849	[144]	[204]	6	hSpCas9	negative selection	75310
74530660	74530683	2	+	26472758	Jiyoye	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	0.11499463001256316	[59]	[48]	0	hSpCas9	negative selection	75311
74530650	74530673	2	+	26472758	Jiyoye	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	0.7905040210573793	[22]	[29]	5	hSpCas9	negative selection	75312
74531608	74531631	2	+	26472758	Jiyoye	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-0.5387371029318293	[444]	[230]	-4	hSpCas9	negative selection	75313
74530003	74530026	2	+	26472758	Jiyoye	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-0.5188240370503496	[37]	[19]	-4	hSpCas9	negative selection	75314
74530108	74530131	2	-	26472758	Jiyoye	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	2.0394435970053864	[59]	[185]	8	hSpCas9	negative selection	75315
74530168	74530191	2	-	26472758	Jiyoye	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	-0.8193331483028065	[116]	[49]	-5	hSpCas9	negative selection	75316
74530355	74530378	2	+	26472758	Jiyoye	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	0.1817991017306041	[241]	[206]	1	hSpCas9	negative selection	75317
74530425	74530448	2	-	26472758	Jiyoye	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	0.5297946681698291	[123]	[134]	4	hSpCas9	negative selection	75319
74530620	74530643	2	-	26472758	Jiyoye	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	0.4071753815058734	[49]	[49]	3	hSpCas9	negative selection	75320
74529417	74529440	2	+	26472758	KBM7	viability	GAAAGAGGCGCAGGACGAGGAGG	HTRA2	ENSG00000115317	0.21281370242081457	[483,395]	[219,254]	2	hSpCas9	negative selection	204182
74530468	74530491	2	+	26472758	KBM7	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-0.5699368926915752	[502,331]	[127,131]	-5	hSpCas9	negative selection	266428
74530660	74530683	2	+	26472758	KBM7	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	-0.5623765564371045	[339,166]	[119,40]	-5	hSpCas9	negative selection	266429
74530650	74530673	2	+	26472758	KBM7	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-0.3548534719356897	[222,99]	[78,37]	-3	hSpCas9	negative selection	266430
74531608	74531631	2	+	26472758	KBM7	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	0.07658615123640367	[1276,1087]	[803,387]	0	hSpCas9	negative selection	266431
74530003	74530026	2	+	26472758	KBM7	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-0.6366784031291757	[352,180]	[59,94]	-5	hSpCas9	negative selection	266432
74530108	74530131	2	-	26472758	KBM7	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	0.8881814035529384	[476,378]	[380,359]	8	hSpCas9	negative selection	266433
74530168	74530191	2	-	26472758	KBM7	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	0.22468814237688495	[270,233]	[206,76]	2	hSpCas9	negative selection	266434
74530355	74530378	2	+	26472758	KBM7	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-0.1576423961559431	[904,1051]	[603,250]	-1	hSpCas9	negative selection	266435
74530425	74530448	2	-	26472758	KBM7	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-0.6211495496878805	[599,662]	[204,185]	-5	hSpCas9	negative selection	266437
74530620	74530643	2	-	26472758	KBM7	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-0.8801205088097553	[544,487]	[181,86]	-6	hSpCas9	negative selection	266438
74529417	74529440	2	+	26472758	Raji	viability	GAAAGAGGCGCAGGACGAGGAGG	HTRA2	ENSG00000115317	-1.5392180311399426	[262]	[20]	-8	hSpCas9	negative selection	395300
74530468	74530491	2	+	26472758	Raji	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	0.5040425053375888	[236]	[77]	5	hSpCas9	negative selection	457546
74530660	74530683	2	+	26472758	Raji	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	0.535841550414765	[106]	[35]	5	hSpCas9	negative selection	457547
74530650	74530673	2	+	26472758	Raji	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-1.366547652958813	[99]	[8]	-7	hSpCas9	negative selection	457548
74531608	74531631	2	+	26472758	Raji	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	0.6455977769032762	[459]	[166]	6	hSpCas9	negative selection	457549
74530003	74530026	2	+	26472758	Raji	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	0.9585201494591167	[101]	[45]	8	hSpCas9	negative selection	457550
74530108	74530131	2	-	26472758	Raji	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	1.2057872394345939	[169]	[90]	9	hSpCas9	negative selection	457551
74530168	74530191	2	-	26472758	Raji	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	0.753746580758899	[137]	[53]	7	hSpCas9	negative selection	457552
74530355	74530378	2	+	26472758	Raji	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-0.880038398546931	[570]	[71]	-6	hSpCas9	negative selection	457553
74530425	74530448	2	-	26472758	Raji	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-0.29904083360053635	[333]	[62]	-3	hSpCas9	negative selection	457555
74530620	74530643	2	-	26472758	Raji	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	0.4340651602315965	[302]	[94]	4	hSpCas9	negative selection	457556
74529417	74529440	2	+	26472758	K562	viability	GAAAGAGGCGCAGGACGAGGAGG	HTRA2	ENSG00000115317	-2.0081883067170088	[385]	[80]	-7	hSpCas9	negative selection	586418
74530468	74530491	2	+	26472758	K562	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-0.4378409744096241	[413]	[257]	-3	hSpCas9	negative selection	648664
74530660	74530683	2	+	26472758	K562	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	0.5830431114261228	[188]	[238]	5	hSpCas9	negative selection	648665
74530650	74530673	2	+	26472758	K562	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-0.11172508255882851	[127]	[99]	-1	hSpCas9	negative selection	648666
74531608	74531631	2	+	26472758	K562	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-0.13203337340898869	[909]	[700]	-1	hSpCas9	negative selection	648667
74530003	74530026	2	+	26472758	K562	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-1.704050971693471	[219]	[56]	-7	hSpCas9	negative selection	648668
74530108	74530131	2	-	26472758	K562	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	1.319186496068419	[234]	[494]	9	hSpCas9	negative selection	648669
74530168	74530191	2	-	26472758	K562	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	-0.9707871530767318	[266]	[114]	-5	hSpCas9	negative selection	648670
74530355	74530378	2	+	26472758	K562	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-0.8253223436241142	[889]	[423]	-5	hSpCas9	negative selection	648671
74530425	74530448	2	-	26472758	K562	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-0.5199530238404113	[619]	[364]	-3	hSpCas9	negative selection	648673
74530620	74530643	2	-	26472758	K562	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-0.7626360298675036	[409]	[203]	-4	hSpCas9	negative selection	648674
74530045	74530068	2	-	26627737	DLD1	viability	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	-1.4979137221611687	[807]	[98,91,78]	-8	hSpCas9	negative selection	812774
74530621	74530644	2	-	26627737	DLD1	viability	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	-2.0801129070495907	[132]	[9,0,16]	-9	hSpCas9	negative selection	812775
74530940	74530963	2	+	26627737	DLD1	viability	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-1.8204434015740834	[1056]	[84,171,35]	-8	hSpCas9	negative selection	812776
74531359	74531382	2	-	26627737	DLD1	viability	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	-0.39474626170332316	[566]	[93,192,121]	-4	hSpCas9	negative selection	812777
74531646	74531669	2	-	26627737	DLD1	viability	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-2.0743212910411377	[712]	[63,4,82]	-9	hSpCas9	negative selection	812778
74531865	74531888	2	+	26627737	DLD1	viability	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	0.06209626325022277	[526]	[194,200,127]	0	hSpCas9	negative selection	812779
74530045	74530068	2	-	26627737	GBM cells	viability after 5 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.023304737122875396	[421]	[219,239]	0	hSpCas9	negative selection	895089
74530621	74530644	2	-	26627737	GBM cells	viability after 5 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.36248126809218806	[94]	[53,76]	5	hSpCas9	negative selection	895090
74530940	74530963	2	+	26627737	GBM cells	viability after 5 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.5112881564782428	[694]	[266,255]	-7	hSpCas9	negative selection	895091
74531359	74531382	2	-	26627737	GBM cells	viability after 5 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	-0.1617274764541501	[412]	[182,212]	-3	hSpCas9	negative selection	895092
74531646	74531669	2	-	26627737	GBM cells	viability after 5 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-0.22553349603880268	[362]	[142,189]	-4	hSpCas9	negative selection	895093
74531865	74531888	2	+	26627737	GBM cells	viability after 5 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	-0.240181734779976	[271]	[135,110]	-4	hSpCas9	negative selection	895094
74530045	74530068	2	-	26627737	GBM cells	viability after 13 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	-0.37169020865094127	[421]	[171,180]	-4	hSpCas9	negative selection	977404
74530621	74530644	2	-	26627737	GBM cells	viability after 13 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.14364791127175458	[94]	[78,38]	1	hSpCas9	negative selection	977405
74530940	74530963	2	+	26627737	GBM cells	viability after 13 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.34408979397744055	[694]	[381,227]	-4	hSpCas9	negative selection	977406
74531359	74531382	2	-	26627737	GBM cells	viability after 13 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.09735941215341781	[412]	[247,232]	1	hSpCas9	negative selection	977407
74531646	74531669	2	-	26627737	GBM cells	viability after 13 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-0.6654745923204866	[362]	[132,116]	-7	hSpCas9	negative selection	977408
74531865	74531888	2	+	26627737	GBM cells	viability after 13 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	-0.015898493984287485	[271]	[140,149]	0	hSpCas9	negative selection	977409
74530045	74530068	2	-	26627737	GBM cells	viability after 21 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	-0.9736558017429089	[421]	[110,121]	-7	hSpCas9	negative selection	1059719
74530621	74530644	2	-	26627737	GBM cells	viability after 21 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	-0.05444836204036574	[94]	[44,53]	0	hSpCas9	negative selection	1059720
74530940	74530963	2	+	26627737	GBM cells	viability after 21 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.6114900637845739	[694]	[243,249]	-5	hSpCas9	negative selection	1059721
74531359	74531382	2	-	26627737	GBM cells	viability after 21 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.317341210716108	[412]	[312,248]	3	hSpCas9	negative selection	1059722
74531646	74531669	2	-	26627737	GBM cells	viability after 21 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-0.2650633290576152	[362]	[184,144]	-2	hSpCas9	negative selection	1059723
74531865	74531888	2	+	26627737	GBM cells	viability after 21 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	-0.10196120917478707	[271]	[144,130]	-1	hSpCas9	negative selection	1059724
74530045	74530068	2	-	26627737	RPE1	viability after 9 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	-0.20958190565899282	[1078]	[199,410]	-1	hSpCas9	negative selection	1142034
74530621	74530644	2	-	26627737	RPE1	viability after 9 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.9045230018542256	[288]	[164,174]	6	hSpCas9	negative selection	1142035
74530940	74530963	2	+	26627737	RPE1	viability after 9 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	0.17164961485653252	[2505]	[877,890]	1	hSpCas9	negative selection	1142036
74531359	74531382	2	-	26627737	RPE1	viability after 9 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.22747156501074417	[998]	[201,577]	1	hSpCas9	negative selection	1142037
74531646	74531669	2	-	26627737	RPE1	viability after 9 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	0.01989644760811149	[1147]	[342,391]	0	hSpCas9	negative selection	1142038
74531865	74531888	2	+	26627737	RPE1	viability after 9 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	0.2637630857404216	[1181]	[397,503]	1	hSpCas9	negative selection	1142039
74530045	74530068	2	-	26627737	RPE1	viability after 12 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.30812779924029426	[1078]	[406,307]	2	hSpCas9	negative selection	1224349
74530621	74530644	2	-	26627737	RPE1	viability after 12 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.8801920544084624	[288]	[156,127]	5	hSpCas9	negative selection	1224350
74530940	74530963	2	+	26627737	RPE1	viability after 12 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.029049378857289865	[2505]	[756,556]	0	hSpCas9	negative selection	1224351
74531359	74531382	2	-	26627737	RPE1	viability after 12 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.5643503677995054	[998]	[256,544]	4	hSpCas9	negative selection	1224352
74531646	74531669	2	-	26627737	RPE1	viability after 12 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	0.40332670793413183	[1147]	[404,410]	2	hSpCas9	negative selection	1224353
74531865	74531888	2	+	26627737	RPE1	viability after 12 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	0.16887735552470495	[1181]	[356,356]	1	hSpCas9	negative selection	1224354
74530045	74530068	2	-	26627737	RPE1	viability after 15 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.16835352259400888	[1078]	[398,288]	1	hSpCas9	negative selection	1306664
74530621	74530644	2	-	26627737	RPE1	viability after 15 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.8475831314651857	[288]	[168,125]	5	hSpCas9	negative selection	1306665
74530940	74530963	2	+	26627737	RPE1	viability after 15 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	0.021887165634379757	[2505]	[959,487]	0	hSpCas9	negative selection	1306666
74531359	74531382	2	-	26627737	RPE1	viability after 15 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.7390133891592319	[998]	[321,615]	4	hSpCas9	negative selection	1306667
74531646	74531669	2	-	26627737	RPE1	viability after 15 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	0.368146855675753	[1147]	[410,426]	2	hSpCas9	negative selection	1306668
74531865	74531888	2	+	26627737	RPE1	viability after 15 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	-0.6436764457771443	[1181]	[212,214]	-4	hSpCas9	negative selection	1306669
74530045	74530068	2	-	26627737	RPE1	viability after 18 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.09673958899140761	[1078]	[307,314]	0	hSpCas9	negative selection	1388979
74530621	74530644	2	-	26627737	RPE1	viability after 18 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.8166622540547529	[288]	[118,156]	5	hSpCas9	negative selection	1388980
74530940	74530963	2	+	26627737	RPE1	viability after 18 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	0.10502371583478354	[2505]	[766,684]	0	hSpCas9	negative selection	1388981
74531359	74531382	2	-	26627737	RPE1	viability after 18 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.45754019102787535	[998]	[288,456]	3	hSpCas9	negative selection	1388982
74531646	74531669	2	-	26627737	RPE1	viability after 18 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	0.2953724584341253	[1147]	[385,373]	2	hSpCas9	negative selection	1388983
74531865	74531888	2	+	26627737	RPE1	viability after 18 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	-0.19427892879084457	[1181]	[199,362]	-1	hSpCas9	negative selection	1388984
74530045	74530068	2	-	26627737	HeLa	viability after 8 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	-0.2755591158292422	[567]	[227,84,297]	-3	hSpCas9	negative selection	1471294
74530621	74530644	2	-	26627737	HeLa	viability after 8 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.06812771399000228	[176]	[68,109,61]	0	hSpCas9	negative selection	1471295
74530940	74530963	2	+	26627737	HeLa	viability after 8 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.7273014367152653	[1630]	[471,489,339]	-6	hSpCas9	negative selection	1471296
74531359	74531382	2	-	26627737	HeLa	viability after 8 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.6597708282648286	[333]	[266,184,243]	5	hSpCas9	negative selection	1471297
74531646	74531669	2	-	26627737	HeLa	viability after 8 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-0.2314805703852732	[605]	[246,299,137]	-2	hSpCas9	negative selection	1471298
74531865	74531888	2	+	26627737	HeLa	viability after 8 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	1.01990447044505	[289]	[173,265,305]	7	hSpCas9	negative selection	1471299
74530045	74530068	2	-	26627737	HeLa	viability after 12 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	-0.048073547340389045	[567]	[199,267,207]	0	hSpCas9	negative selection	1553609
74530621	74530644	2	-	26627737	HeLa	viability after 12 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	-1.1087784095372442	[176]	[13,44,40]	-7	hSpCas9	negative selection	1553610
74530940	74530963	2	+	26627737	HeLa	viability after 12 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.5312125590251231	[1630]	[65,188,1161]	-5	hSpCas9	negative selection	1553611
74531359	74531382	2	-	26627737	HeLa	viability after 12 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.6126012137192062	[333]	[216,81,347]	5	hSpCas9	negative selection	1553612
74531646	74531669	2	-	26627737	HeLa	viability after 12 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	0.2959920863157034	[605]	[609,148,188]	2	hSpCas9	negative selection	1553613
74531865	74531888	2	+	26627737	HeLa	viability after 12 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	0.7546966471951246	[289]	[314,125,176]	6	hSpCas9	negative selection	1553614
74530045	74530068	2	-	26627737	HeLa	viability after 15 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.28797847108684993	[567]	[215,141,506]	2	hSpCas9	negative selection	1635924
74530621	74530644	2	-	26627737	HeLa	viability after 15 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.13965764422690397	[176]	[44,72,123]	1	hSpCas9	negative selection	1635925
74530940	74530963	2	+	26627737	HeLa	viability after 15 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.4267282913560313	[1630]	[240,75,1223]	-4	hSpCas9	negative selection	1635926
74531359	74531382	2	-	26627737	HeLa	viability after 15 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.7499324442859358	[333]	[87,223,387]	6	hSpCas9	negative selection	1635927
74531646	74531669	2	-	26627737	HeLa	viability after 15 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-0.32802125174755237	[605]	[239,164,182]	-3	hSpCas9	negative selection	1635928
74531865	74531888	2	+	26627737	HeLa	viability after 15 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	0.8513222625955126	[289]	[125,60,472]	6	hSpCas9	negative selection	1635929
74530045	74530068	2	-	26627737	HeLa	viability after 18 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.2827338450012016	[567]	[136,124,506]	2	hSpCas9	negative selection	1718239
74530621	74530644	2	-	26627737	HeLa	viability after 18 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.13825325347288753	[176]	[31,57,123]	1	hSpCas9	negative selection	1718240
74530940	74530963	2	+	26627737	HeLa	viability after 18 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.43251635163173074	[1630]	[156,63,1223]	-4	hSpCas9	negative selection	1718241
74531359	74531382	2	-	26627737	HeLa	viability after 18 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.7459460737771376	[333]	[58,183,387]	6	hSpCas9	negative selection	1718242
74531646	74531669	2	-	26627737	HeLa	viability after 18 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-0.32324246882739455	[605]	[157,141,182]	-3	hSpCas9	negative selection	1718243
74531865	74531888	2	+	26627737	HeLa	viability after 18 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	0.8466151870244824	[289]	[81,51,472]	6	hSpCas9	negative selection	1718244
74530045	74530068	2	-	26627737	HCT116	viability after 6 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.4055696262555627	[1037]	[511,52]	2	hSpCas9	negative selection	1800554
74530621	74530644	2	-	26627737	HCT116	viability after 6 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	-5.90059535114338	[379]	[0,0]	-9	hSpCas9	negative selection	1800555
74530940	74530963	2	+	26627737	HCT116	viability after 6 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	0.25001822298465615	[1557]	[376,243]	1	hSpCas9	negative selection	1800556
74531359	74531382	2	-	26627737	HCT116	viability after 6 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.03298837607788818	[982]	[170,150]	0	hSpCas9	negative selection	1800557
74531646	74531669	2	-	26627737	HCT116	viability after 6 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	1.7241025378208055	[809]	[401,430]	8	hSpCas9	negative selection	1800558
74531865	74531888	2	+	26627737	HCT116	viability after 6 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	1.7852917053764445	[592]	[194,390]	8	hSpCas9	negative selection	1800559
74530045	74530068	2	-	26627737	HCT116	viability after 8 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	-0.5209586643816162	[303]	[64,142,140]	-6	hSpCas9	negative selection	1882869
74530621	74530644	2	-	26627737	HCT116	viability after 8 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.13002729999398932	[92]	[48,53,64]	1	hSpCas9	negative selection	1882870
74530940	74530963	2	+	26627737	HCT116	viability after 8 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.06974090762345275	[735]	[457,354,347]	0	hSpCas9	negative selection	1882871
74531359	74531382	2	-	26627737	HCT116	viability after 8 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.6390223514669654	[308]	[291,243,259]	6	hSpCas9	negative selection	1882872
74531646	74531669	2	-	26627737	HCT116	viability after 8 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-0.26913685249870223	[527]	[195,246,279]	-3	hSpCas9	negative selection	1882873
74531865	74531888	2	+	26627737	HCT116	viability after 8 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	0.03182490912107572	[439]	[273,300,169]	0	hSpCas9	negative selection	1882874
74530045	74530068	2	-	26627737	HCT116	viability after 9 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.3447937771472379	[1037]	[518,219]	2	hSpCas9	negative selection	1965184
74530621	74530644	2	-	26627737	HCT116	viability after 9 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	-2.290609545195355	[379]	[27,14]	-9	hSpCas9	negative selection	1965185
74530940	74530963	2	+	26627737	HCT116	viability after 9 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.9580512902285095	[1557]	[331,120]	-6	hSpCas9	negative selection	1965186
74531359	74531382	2	-	26627737	HCT116	viability after 9 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	-0.5694071613378248	[982]	[239,126]	-4	hSpCas9	negative selection	1965187
74531646	74531669	2	-	26627737	HCT116	viability after 9 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	0.3857097856686856	[809]	[257,301]	3	hSpCas9	negative selection	1965188
74531865	74531888	2	+	26627737	HCT116	viability after 9 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	1.5996942279589514	[592]	[518,448]	8	hSpCas9	negative selection	1965189
74530045	74530068	2	-	26627737	HCT116	viability after 12 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.036525694965868535	[303]	[103,170,221]	0	hSpCas9	negative selection	2047499
74530621	74530644	2	-	26627737	HCT116	viability after 12 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	-0.028676754455611908	[92]	[40,74,28]	0	hSpCas9	negative selection	2047500
74530940	74530963	2	+	26627737	HCT116	viability after 12 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.18310891622379266	[735]	[492,312,201]	-2	hSpCas9	negative selection	2047501
74531359	74531382	2	-	26627737	HCT116	viability after 12 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.5249509995997786	[308]	[210,193,296]	5	hSpCas9	negative selection	2047502
74531646	74531669	2	-	26627737	HCT116	viability after 12 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-0.275962311934007	[527]	[107,387,205]	-3	hSpCas9	negative selection	2047503
74531865	74531888	2	+	26627737	HCT116	viability after 12 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	-0.4628829787316384	[439]	[165,148,187]	-5	hSpCas9	negative selection	2047504
74530045	74530068	2	-	26627737	HCT116	viability after 15 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.22385805147584753	[303]	[202,157,249]	2	hSpCas9	negative selection	2129814
74530621	74530644	2	-	26627737	HCT116	viability after 15 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.2255227730274425	[92]	[51,65,67]	2	hSpCas9	negative selection	2129815
74530940	74530963	2	+	26627737	HCT116	viability after 15 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.08925658129372871	[735]	[517,402,286]	-1	hSpCas9	negative selection	2129816
74531359	74531382	2	-	26627737	HCT116	viability after 15 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.8603527004543805	[308]	[289,383,288]	7	hSpCas9	negative selection	2129817
74531646	74531669	2	-	26627737	HCT116	viability after 15 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-0.38639248824951244	[527]	[258,188,250]	-4	hSpCas9	negative selection	2129818
74531865	74531888	2	+	26627737	HCT116	viability after 15 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	-0.2348129057712311	[439]	[217,244,181]	-2	hSpCas9	negative selection	2129819
74530045	74530068	2	-	26627737	HCT116	viability after 18 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.14988508189621616	[303]	[90,236,155]	1	hSpCas9	negative selection	2212129
74530621	74530644	2	-	26627737	HCT116	viability after 18 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.29600140448413725	[92]	[38,66,58]	2	hSpCas9	negative selection	2212130
74530940	74530963	2	+	26627737	HCT116	viability after 18 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	0.5354440301439005	[735]	[640,362,554]	4	hSpCas9	negative selection	2212131
74531359	74531382	2	-	26627737	HCT116	viability after 18 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.6438709426088469	[308]	[216,190,297]	5	hSpCas9	negative selection	2212132
74531646	74531669	2	-	26627737	HCT116	viability after 18 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	0.05851941729363208	[527]	[380,256,154]	0	hSpCas9	negative selection	2212133
74531865	74531888	2	+	26627737	HCT116	viability after 18 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	-0.5714192029527035	[439]	[116,191,115]	-5	hSpCas9	negative selection	2212134
74529408	74529431	2	+	24336569	HL60	viability	GGATCCCGAGAAAGAGGCGCAGG	HTRA2	ENSG00000115317	-1.4162543464533084	[506]	[401]	-8	hSpCas9	negative selection	2249244
74529413	74529436	2	-	24336569	HL60	viability	CTCGTCCTGCGCCTCTTTCTCGG	HTRA2	ENSG00000115317	0.17646447793431413	[400]	[958]	1	hSpCas9	negative selection	2249245
74529431	74529454	2	+	24336569	HL60	viability	ACGAGGAGGCAGAACCCGACTGG	HTRA2	ENSG00000115317	0.08364826694951671	[366]	[822]	0	hSpCas9	negative selection	2249246
74529445	74529468	2	-	24336569	HL60	viability	TGCTGCTCTACGCGCCAGTCGGG	HTRA2	ENSG00000115317	0.8102830087190802	[248]	[923]	6	hSpCas9	negative selection	2249247
74529459	74529482	2	+	24336569	HL60	viability	AGAGCAGCAGCACGAGCAGTAGG	HTRA2	ENSG00000115317	-0.45715909973250224	[1048]	[1616]	-4	hSpCas9	negative selection	2249248
74529473	74529496	2	+	24336569	HL60	viability	AGCAGTAGGAAGCAGTCACCCGG	HTRA2	ENSG00000115317	0.10512147101324576	[1520]	[3461]	1	hSpCas9	negative selection	2249249
74529481	74529504	2	+	24336569	HL60	viability	GAAGCAGTCACCCGGAAGCCTGG	HTRA2	ENSG00000115317	0.8960518852197248	[290]	[1145]	7	hSpCas9	negative selection	2249250
74529579	74529602	2	-	24336569	HL60	viability	AGCGGCTCTTTGACTCGCACCGG	HTRA2	ENSG00000115317	0.5539381386394129	[177]	[552]	5	hSpCas9	negative selection	2249251
74529607	74529630	2	-	24336569	HL60	viability	ATGGAGCTTCCCTCAGGGCCGGG	HTRA2	ENSG00000115317	1.4591042807338064	[131]	[767]	8	hSpCas9	negative selection	2249252
74529612	74529635	2	-	24336569	HL60	viability	CAGTTATGGAGCTTCCCTCAGGG	HTRA2	ENSG00000115317	-0.5741090964938851	[540]	[768]	-5	hSpCas9	negative selection	2249253
74529999	74530022	2	+	24336569	HL60	viability	CGGAGCTGATGGCTGCGCCGAGG	HTRA2	ENSG00000115317	-1.0897475398878385	[523]	[520]	-7	hSpCas9	negative selection	2271030
74530004	74530027	2	+	24336569	HL60	viability	CTGATGGCTGCGCCGAGGGCGGG	HTRA2	ENSG00000115317	-0.8060459703392701	[579]	[701]	-6	hSpCas9	negative selection	2271031
74530030	74530053	2	+	24336569	HL60	viability	GGGTGCAGGCTGGAGCCTTCGGG	HTRA2	ENSG00000115317	-0.6119788173276759	[519]	[719]	-5	hSpCas9	negative selection	2271032
74530035	74530058	2	+	24336569	HL60	viability	CAGGCTGGAGCCTTCGGGCATGG	HTRA2	ENSG00000115317	0.7556295280248522	[486]	[1739]	6	hSpCas9	negative selection	2271033
74530045	74530068	2	-	24336569	HL60	viability	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	2.6874166736140723	[56]	[776]	9	hSpCas9	negative selection	2271034
74530102	74530125	2	-	24336569	HL60	viability	TCAGCAGGGCCCGGAGGTCAGGG	HTRA2	ENSG00000115317	0.010307439814789432	[707]	[1508]	0	hSpCas9	negative selection	2271035
74530108	74530131	2	-	24336569	HL60	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	1.8635727750893136	[524]	[4042]	9	hSpCas9	negative selection	2271036
74530116	74530139	2	-	24336569	HL60	viability	AGAAGTTCCTGACGTCAGCAGGG	HTRA2	ENSG00000115317	-0.7871899279156263	[768]	[942]	-6	hSpCas9	negative selection	2271037
74530143	74530166	2	-	24336569	HL60	viability	CCCATAAGTCACTCGGGCCCGGG	HTRA2	ENSG00000115317	-0.1698199750497431	[201]	[379]	-1	hSpCas9	negative selection	2271038
74530169	74530192	2	-	24336569	HL60	viability	GACAACCGGGCCCAGAGACTGGG	HTRA2	ENSG00000115317	0.825426494979622	[111]	[419]	6	hSpCas9	negative selection	2271039
74529408	74529431	2	+	24336569	KBM7	viability	GGATCCCGAGAAAGAGGCGCAGG	HTRA2	ENSG00000115317	-0.2517046046679168	[501]	[1149]	-2	hSpCas9	negative selection	2316421
74529413	74529436	2	-	24336569	KBM7	viability	CTCGTCCTGCGCCTCTTTCTCGG	HTRA2	ENSG00000115317	1.421176270172865	[183]	[1343]	9	hSpCas9	negative selection	2316422
74529431	74529454	2	+	24336569	KBM7	viability	ACGAGGAGGCAGAACCCGACTGG	HTRA2	ENSG00000115317	-0.47964040578118117	[363]	[711]	-4	hSpCas9	negative selection	2316423
74529445	74529468	2	-	24336569	KBM7	viability	TGCTGCTCTACGCGCCAGTCGGG	HTRA2	ENSG00000115317	0.2614117700402794	[426]	[1395]	2	hSpCas9	negative selection	2316424
74529459	74529482	2	+	24336569	KBM7	viability	AGAGCAGCAGCACGAGCAGTAGG	HTRA2	ENSG00000115317	-0.5244822208997151	[837]	[1588]	-4	hSpCas9	negative selection	2316425
74529473	74529496	2	+	24336569	KBM7	viability	AGCAGTAGGAAGCAGTCACCCGG	HTRA2	ENSG00000115317	0.14662397653869097	[1244]	[3758]	1	hSpCas9	negative selection	2316426
74529481	74529504	2	+	24336569	KBM7	viability	GAAGCAGTCACCCGGAAGCCTGG	HTRA2	ENSG00000115317	0.050612834697419715	[433]	[1225]	0	hSpCas9	negative selection	2316427
74529579	74529602	2	-	24336569	KBM7	viability	AGCGGCTCTTTGACTCGCACCGG	HTRA2	ENSG00000115317	-1.0080995560037254	[277]	[376]	-6	hSpCas9	negative selection	2316428
74529607	74529630	2	-	24336569	KBM7	viability	ATGGAGCTTCCCTCAGGGCCGGG	HTRA2	ENSG00000115317	0.8579798259314684	[389]	[1927]	7	hSpCas9	negative selection	2316429
74529612	74529635	2	-	24336569	KBM7	viability	CAGTTATGGAGCTTCCCTCAGGG	HTRA2	ENSG00000115317	-0.7869169696958739	[395]	[625]	-6	hSpCas9	negative selection	2316430
74529999	74530022	2	+	24336569	KBM7	viability	CGGAGCTGATGGCTGCGCCGAGG	HTRA2	ENSG00000115317	0.33047358966052287	[269]	[925]	3	hSpCas9	negative selection	2338207
74530004	74530027	2	+	24336569	KBM7	viability	CTGATGGCTGCGCCGAGGGCGGG	HTRA2	ENSG00000115317	0.8589865134717722	[320]	[1587]	7	hSpCas9	negative selection	2338208
74530030	74530053	2	+	24336569	KBM7	viability	GGGTGCAGGCTGGAGCCTTCGGG	HTRA2	ENSG00000115317	-0.2087923369617659	[299]	[707]	-2	hSpCas9	negative selection	2338209
74530035	74530058	2	+	24336569	KBM7	viability	CAGGCTGGAGCCTTCGGGCATGG	HTRA2	ENSG00000115317	-0.22705313386973336	[441]	[1029]	-2	hSpCas9	negative selection	2338210
74530045	74530068	2	-	24336569	KBM7	viability	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	2.0442738997807925	[55]	[629]	9	hSpCas9	negative selection	2338211
74530102	74530125	2	-	24336569	KBM7	viability	TCAGCAGGGCCCGGAGGTCAGGG	HTRA2	ENSG00000115317	-0.15739767939931526	[679]	[1662]	-1	hSpCas9	negative selection	2338212
74530108	74530131	2	-	24336569	KBM7	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	0.48522539991245495	[845]	[3229]	4	hSpCas9	negative selection	2338213
74530116	74530139	2	-	24336569	KBM7	viability	AGAAGTTCCTGACGTCAGCAGGG	HTRA2	ENSG00000115317	0.3442348746129435	[399]	[1384]	3	hSpCas9	negative selection	2338214
74530143	74530166	2	-	24336569	KBM7	viability	CCCATAAGTCACTCGGGCCCGGG	HTRA2	ENSG00000115317	0.9193640145289163	[182]	[943]	7	hSpCas9	negative selection	2338215
74530169	74530192	2	-	24336569	KBM7	viability	GACAACCGGGCCCAGAGACTGGG	HTRA2	ENSG00000115317	0.20063486039841172	[237]	[745]	1	hSpCas9	negative selection	2338216
74529916	74529939	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGTAGGACGCGGGGCACGCCGG	HTRA2	ENSG00000115317	1.605585206155481	[28,36]	[1,43]	6	dCas9-VP64	positive selection	2472989
74529964	74529987	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTCTGAGTAGGGCGGGCGAGG	HTRA2	ENSG00000115317	-2.106633093406449	[96,16]	[2,1]	-9	dCas9-VP64	positive selection	2472990
74529988	74530011	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAGCCAAGGCGGAGCTGATGG	HTRA2	ENSG00000115317	3.0073192780770523	[79,8]	[143,6]	8	dCas9-VP64	positive selection	2472991
74529916	74529939	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGTAGGACGCGGGGCACGCCGG	HTRA2	ENSG00000115317	0.16507662009877944	[6,37]	[6,8]	1	dCas9-VP64	positive selection	2568244
74529964	74529987	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTCTGAGTAGGGCGGGCGAGG	HTRA2	ENSG00000115317	7.016098221896479	[19,0]	[957,1]	9	dCas9-VP64	positive selection	2568245
74529988	74530011	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAGCCAAGGCGGAGCTGATGG	HTRA2	ENSG00000115317	-0.06513427326964694	[19,60]	[2,20]	0	dCas9-VP64	positive selection	2568246
74530116	74530139	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAAGTTCCTGACGTCAGCAGGG	HTRA2	ENSG00000115317	0.2045521083612326	[3,3]	[3,3]	4	hSpCas9	positive selection	2994535
74530485	74530508	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGGATCTCGATATAGACCACGG	HTRA2	ENSG00000115317	-1.0039001043078908	[3,3]	[1,0]	-9	hSpCas9	positive selection	2994536
74530000	74530023	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGGAGCTGATGGCTGCGCCGAGG	HTRA2	ENSG00000115317	0.6189792189738708	[1,1]	[1,3]	9	hSpCas9	positive selection	2994537
74530618	74530641	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACCCTTTCTTGGGCCGCGAGG	HTRA2	ENSG00000115317	-0.23626770614356407	[3,2]	[1,2]	-3	hSpCas9	positive selection	2994538
74530116	74530139	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAAGTTCCTGACGTCAGCAGGG	HTRA2	ENSG00000115317	-0.18153092311521654	[3,3]	[2,1]	-3	hSpCas9	positive selection	3062393
74530485	74530508	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGGATCTCGATATAGACCACGG	HTRA2	ENSG00000115317	-0.7108001658758154	[3,3]	[1,0]	-8	hSpCas9	positive selection	3062394
74530000	74530023	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGGAGCTGATGGCTGCGCCGAGG	HTRA2	ENSG00000115317	-0.45127440633717997	[1,1]	[0,0]	-6	hSpCas9	positive selection	3062395
74530618	74530641	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACCCTTTCTTGGGCCGCGAGG	HTRA2	ENSG00000115317	-0.7445974870983842	[3,3]	[2,0]	-8	hSpCas9	positive selection	3062396
74531914	74531937		-	24336571	A375	resistance to PLX after 7 days	AAAGCTCATACCTGGGACTCAGG	HTRA2	ENSG00000115317	-0.074837374077935	[20,19]	[17,20]	-2	hSpCas9	positive selection	3120121
74530633	74530656		+	24336571	A375	resistance to PLX after 7 days	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	0.017333812830645057	[9,8]	[10,8]	0	hSpCas9	positive selection	3120122
74531876	74531899		+	24336571	A375	resistance to PLX after 7 days	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.14155607541889198	[9,11]	[8,9]	-4	hSpCas9	positive selection	3120123
74531914	74531937		-	24336571	A375	resistance to PLX after 14 days	AAAGCTCATACCTGGGACTCAGG	HTRA2	ENSG00000115317	0.1783906700253025	[20,18]	[9,10]	1	hSpCas9	positive selection	3177914
74530633	74530656		+	24336571	A375	resistance to PLX after 14 days	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	0.0011483657440943817	[6,7]	[3,1]	0	hSpCas9	positive selection	3177915
74531876	74531899		+	24336571	A375	resistance to PLX after 14 days	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.8356688752110425	[11,13]	[2,2]	-8	hSpCas9	positive selection	3177916
74531914	74531937		-	24336571	A375	viability after 7 days	AAAGCTCATACCTGGGACTCAGG	HTRA2	ENSG00000115317	-0.3365116366574271	[26]	[20,19]	-5	hSpCas9	negative selection	3235707
74530633	74530656		+	24336571	A375	viability after 7 days	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.5600149101091016	[14]	[9,8]	-7	hSpCas9	negative selection	3235708
74531876	74531899		+	24336571	A375	viability after 7 days	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.30623068656474606	[8]	[9,11]	4	hSpCas9	negative selection	3235709
74531914	74531937		-	24336571	A375	viability after 14 days	AAAGCTCATACCTGGGACTCAGG	HTRA2	ENSG00000115317	-0.34557266341666537	[26]	[20,18]	-4	hSpCas9	negative selection	3293500
74530633	74530656		+	24336571	A375	viability after 14 days	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.962544019888633	[14]	[6,7]	-8	hSpCas9	negative selection	3293501
74531876	74531899		+	24336571	A375	viability after 14 days	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.626109129608127	[8]	[11,13]	7	hSpCas9	negative selection	3293502
74531881	74531904	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.17730201619088934	[172,172]	[0,0]	-1	hSpCas9	positive selection	3373552
74530642	74530665	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.3351308258222454	[192,192]	[0,0]	-2	hSpCas9	positive selection	3373553
74531014	74531037	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.05555674383852015	[158,158]	[0,0]	0	hSpCas9	positive selection	3373554
74530116	74530139	2	-	26780180	HT29	viability (Avana library 4 designs)	AGAAGTTCCTGACGTCAGCAGGG	HTRA2	ENSG00000115317	-0.180902390455697	[]	[]	-3	hSpCas9	negative selection	3431869
74530485	74530508	2	-	26780180	HT29	viability (Avana library 4 designs)	CAGGATCTCGATATAGACCACGG	HTRA2	ENSG00000115317	2.4718102216646	[]	[]	8	hSpCas9	negative selection	3431870
74529999	74530022	2	+	26780180	HT29	viability (Avana library 4 designs)	CGGAGCTGATGGCTGCGCCGAGG	HTRA2	ENSG00000115317	1.88800334884247	[]	[]	7	hSpCas9	negative selection	3431871
74530617	74530640	2	+	26780180	HT29	viability (Avana library 4 designs)	GCACCCTTTCTTGGGCCGCGAGG	HTRA2	ENSG00000115317	1.27294460948098	[]	[]	5	hSpCas9	negative selection	3431872
74530485	74530508	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGGATCTCGATATAGACCACGG	HTRA2	ENSG00000115317	-0.312140601009177	[]	[]	0	hSpCas9	negative selection	3517744
74530617	74530640	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACCCTTTCTTGGGCCGCGAGG	HTRA2	ENSG00000115317	6.76629433554541	[]	[]	9	hSpCas9	negative selection	3517745
74529999	74530022	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGGAGCTGATGGCTGCGCCGAGG	HTRA2	ENSG00000115317	3.92892552554792	[]	[]	6	hSpCas9	negative selection	3517746
74530116	74530139	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGTTCCTGACGTCAGCAGGG	HTRA2	ENSG00000115317	4.27315779991001	[]	[]	7	hSpCas9	negative selection	3517747
74530620	74530643	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-1.36942980755477	[]	[]	-2	hSpCas9	negative selection	3517748
74530632	74530655	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGTTCGAGATAGGGACCTCGCGG	HTRA2	ENSG00000115317	4.89243913536002	[]	[]	8	hSpCas9	negative selection	3517749
74530485	74530508	2	-	26780180	A375	viability (Avana lentiGuide)	CAGGATCTCGATATAGACCACGG	HTRA2	ENSG00000115317	3.93796716332944	[]	[]	4	hSpCas9	negative selection	3626403
74530617	74530640	2	+	26780180	A375	viability (Avana lentiGuide)	GCACCCTTTCTTGGGCCGCGAGG	HTRA2	ENSG00000115317	2.86614427162134	[]	[]	3	hSpCas9	negative selection	3626404
74529999	74530022	2	+	26780180	A375	viability (Avana lentiGuide)	CGGAGCTGATGGCTGCGCCGAGG	HTRA2	ENSG00000115317	16.3559952699076	[]	[]	8	hSpCas9	negative selection	3626405
74530116	74530139	2	-	26780180	A375	viability (Avana lentiGuide)	AGAAGTTCCTGACGTCAGCAGGG	HTRA2	ENSG00000115317	3.20279530862359	[]	[]	3	hSpCas9	negative selection	3626406
74530620	74530643	2	-	26780180	A375	viability (Avana lentiGuide)	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	7.22303958430919	[]	[]	5	hSpCas9	negative selection	3626407
74530632	74530655	2	-	26780180	A375	viability (Avana lentiGuide)	CGTTCGAGATAGGGACCTCGCGG	HTRA2	ENSG00000115317	4.1586423641113	[]	[]	4	hSpCas9	negative selection	3626408
74530485	74530508	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGGATCTCGATATAGACCACGG	HTRA2	ENSG00000115317	-0.2918277274552187	[6]	[5,3]	-4	hSpCas9	positive selection	3735062
74530617	74530640	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACCCTTTCTTGGGCCGCGAGG	HTRA2	ENSG00000115317	0.3294129387340548	[3]	[4,4]	8	hSpCas9	positive selection	3735063
74529999	74530022	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGAGCTGATGGCTGCGCCGAGG	HTRA2	ENSG00000115317	-0.20636652630971086	[3]	[2,1]	-3	hSpCas9	positive selection	3735064
74530116	74530139	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGTTCCTGACGTCAGCAGGG	HTRA2	ENSG00000115317	0.28148635797896604	[5]	[6,6]	7	hSpCas9	positive selection	3735065
74530620	74530643	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	0.07624696266866945	[4]	[4,4]	2	hSpCas9	positive selection	3735066
74530632	74530655	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTTCGAGATAGGGACCTCGCGG	HTRA2	ENSG00000115317	0.21260576765941863	[5]	[6,6]	6	hSpCas9	positive selection	3735067
74530485	74530508	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGGATCTCGATATAGACCACGG	HTRA2	ENSG00000115317	-0.41174234168891	[5]	[3,2]	-5	hSpCas9	positive selection	3843669
74530617	74530640	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACCCTTTCTTGGGCCGCGAGG	HTRA2	ENSG00000115317	-0.4559629939574682	[5]	[4,1]	-5	hSpCas9	positive selection	3843670
74529999	74530022	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGAGCTGATGGCTGCGCCGAGG	HTRA2	ENSG00000115317	-0.7435222970804383	[4]	[1,1]	-7	hSpCas9	positive selection	3843671
74530116	74530139	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGTTCCTGACGTCAGCAGGG	HTRA2	ENSG00000115317	0.2866448779506598	[5]	[5,5]	7	hSpCas9	positive selection	3843672
74530620	74530643	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-0.2010561602602607	[4]	[1,4]	-3	hSpCas9	positive selection	3843673
74530632	74530655	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTTCGAGATAGGGACCTCGCGG	HTRA2	ENSG00000115317	0.20930110074241445	[6]	[6,5]	5	hSpCas9	positive selection	3843674
74530642	74530665	2	-	26780180	A375	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	1.25647648547318	[]	[]	6	hSpCas9	negative selection	3949642
74530633	74530656	2	+	26780180	A375	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	1.0127482655218	[]	[]	5	hSpCas9	negative selection	3949643
74530938	74530961	2	+	26780180	A375	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	0.875586538139131	[]	[]	3	hSpCas9	negative selection	3949644
74531014	74531037	2	-	26780180	A375	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	1.57334340534315	[]	[]	8	hSpCas9	negative selection	3949645
74531876	74531899	2	+	26780180	A375	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0	[]	[]	0	hSpCas9	negative selection	3949646
74531881	74531904	2	-	26780180	A375	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	1.29625289045058	[]	[]	7	hSpCas9	negative selection	3949647
74530642	74530665	2	-	26780180	HT29	viability (GeCKOv2 library)	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	1.60344117789418	[]	[]	8	hSpCas9	negative selection	4057608
74530633	74530656	2	+	26780180	HT29	viability (GeCKOv2 library)	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	1.33773357844313	[]	[]	6	hSpCas9	negative selection	4057609
74530938	74530961	2	+	26780180	HT29	viability (GeCKOv2 library)	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	1.65308893518129	[]	[]	8	hSpCas9	negative selection	4057610
74531014	74531037	2	-	26780180	HT29	viability (GeCKOv2 library)	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	2.20077064651994	[]	[]	9	hSpCas9	negative selection	4057611
74531876	74531899	2	+	26780180	HT29	viability (GeCKOv2 library)	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0	[]	[]	0	hSpCas9	negative selection	4057612
74531881	74531904	2	-	26780180	HT29	viability (GeCKOv2 library)	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	1.80838168149981	[]	[]	8	hSpCas9	negative selection	4057613
74531914	74531937	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAAGCTCATACCTGGGACTCAGG	HTRA2	ENSG00000115317	0.006114109540356127	[4]	[2,3]	0	hSpCas9	positive selection	4143706
74530633	74530656	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.18481029460498455	[3]	[2,1]	-4	hSpCas9	positive selection	4143707
74531876	74531899	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.3587356546892165	[3]	[1,1]	-7	hSpCas9	positive selection	4143708
74529359	74529382	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.006474078902287218	[3]	[1,2]	0	hSpCas9	positive selection	4165411
74529446	74529469	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.2994264916512165	[3]	[2,3]	7	hSpCas9	positive selection	4165422
74529361	74529384	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCCAGACAGCGTCCTTCGCAGG	HTRA2	ENSG00000115317	-0.16797373628190962	[3]	[2,1]	-4	hSpCas9	positive selection	4165454
74531914	74531937	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAAGCTCATACCTGGGACTCAGG	HTRA2	ENSG00000115317	-0.4608021354405979	[4]	[1,0,2,0]	-6	hSpCas9	positive selection	4207728
74530633	74530656	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.8160329867845388	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4207729
74531876	74531899	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.07235948880179346	[3]	[0,3,1,0]	-1	hSpCas9	positive selection	4207730
74529359	74529382	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	1.1038249352283072	[2]	[2,0,0,3]	8	hSpCas9	positive selection	4229433
74529446	74529469	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.14514761580696872	[4]	[4,3,1,0]	1	hSpCas9	positive selection	4229444
74529361	74529384	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCCAGACAGCGTCCTTCGCAGG	HTRA2	ENSG00000115317	1.0014383062534082	[3]	[3,0,0,3]	7	hSpCas9	positive selection	4229476
74529359	74529382	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	-0.09344770333310462	[4]	[3,1]	-2	hSpCas9	positive selection	4257571
74529446	74529469	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.26121912127897906	[3]	[3,2]	5	hSpCas9	positive selection	4257572
74530633	74530656	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.23707169142638845	[1]	[1,0]	-5	hSpCas9	positive selection	4276089
74530938	74530961	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.030737627627231298	[3]	[3,1]	0	hSpCas9	positive selection	4276090
74531876	74531899	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.3628918518378901	[0]	[0,0]	7	hSpCas9	positive selection	4276091
74531881	74531904	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.3394509837987507	[3]	[2,0]	-6	hSpCas9	positive selection	4340347
74530642	74530665	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	0.24014419917121638	[3]	[2,2]	5	hSpCas9	positive selection	4340348
74531014	74531037	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.8002457577709154	[3]	[1,0]	-9	hSpCas9	positive selection	4340349
74530142	74530164	2	-	27760321	OCIAML3	viability	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	0.20117573841510195	[906,689]	[621,829]	2	hSpCas9	negative selection	4408452
74530303	74530325	2	+	27760321	OCIAML3	viability	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	-0.46498961002074296	[745,597]	[378,377]	-5	hSpCas9	negative selection	4408453
74530433	74530455	2	-	27760321	OCIAML3	viability	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-0.4494701130188766	[626,505]	[280,376]	-4	hSpCas9	negative selection	4408454
74530498	74530520	2	+	27760321	OCIAML3	viability	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	0.7076975459577219	[561,384]	[478,751]	8	hSpCas9	negative selection	4408455
74530634	74530656	2	+	27760321	OCIAML3	viability	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.9940964701106025	[439,363]	[78,258]	-7	hSpCas9	negative selection	4408456
74530142	74530164	2	-	27760321	OCIAML2	viability	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	-0.19904449845208483	[906,689]	[433,721]	-3	hSpCas9	negative selection	4491915
74530303	74530325	2	+	27760321	OCIAML2	viability	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	0.17686353850248748	[745,597]	[591,635]	2	hSpCas9	negative selection	4491916
74530433	74530455	2	-	27760321	OCIAML2	viability	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-0.42741085095965103	[626,505]	[331,347]	-5	hSpCas9	negative selection	4491917
74530498	74530520	2	+	27760321	OCIAML2	viability	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	0.7155689006017527	[561,384]	[538,729]	8	hSpCas9	negative selection	4491918
74530634	74530656	2	+	27760321	OCIAML2	viability	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-1.2481412120632935	[439,363]	[134,137]	-8	hSpCas9	negative selection	4491919
74530142	74530164	2	-	27760321	MV411	viability	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	1.0561574623566292	[906,689]	[1411,598]	7	hSpCas9	negative selection	4575378
74530303	74530325	2	+	27760321	MV411	viability	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	-0.5709837692611579	[745,597]	[291,303]	-4	hSpCas9	negative selection	4575379
74530433	74530455	2	-	27760321	MV411	viability	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-1.0227792309061337	[626,505]	[158,218]	-6	hSpCas9	negative selection	4575380
74530498	74530520	2	+	27760321	MV411	viability	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	0.590156964248494	[561,384]	[359,621]	4	hSpCas9	negative selection	4575381
74530634	74530656	2	+	27760321	MV411	viability	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	0.11795279578504278	[439,363]	[276,300]	0	hSpCas9	negative selection	4575382
74530142	74530164	2	-	27760321	HL60	viability	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	0.04221626405912482	[906,689]	[727,600]	0	hSpCas9	negative selection	4658841
74530303	74530325	2	+	27760321	HL60	viability	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	-0.06453029878546424	[745,597]	[435,612]	0	hSpCas9	negative selection	4658842
74530433	74530455	2	-	27760321	HL60	viability	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-0.3065954662823047	[626,505]	[408,332]	-3	hSpCas9	negative selection	4658843
74530498	74530520	2	+	27760321	HL60	viability	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	-0.23927121311034522	[561,384]	[264,385]	-3	hSpCas9	negative selection	4658844
74530634	74530656	2	+	27760321	HL60	viability	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.9103143663011446	[439,363]	[171,175]	-7	hSpCas9	negative selection	4658845
74530142	74530164	2	-	27760321	HT1080	viability	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	1.089704311479502	[689,538]	[721,300]	6	hSpCas9	negative selection	4742304
74530303	74530325	2	+	27760321	HT1080	viability	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	-0.25786521452793204	[597,466]	[122,236]	-1	hSpCas9	negative selection	4742305
74530433	74530455	2	-	27760321	HT1080	viability	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-3.3433003807545965	[505,394]	[10,24]	-7	hSpCas9	negative selection	4742306
74530498	74530520	2	+	27760321	HT1080	viability	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	1.6107420980873064	[384,300]	[582,235]	8	hSpCas9	negative selection	4742307
74530634	74530656	2	+	27760321	HT1080	viability	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-1.6615817337556396	[363,283]	[25,56]	-5	hSpCas9	negative selection	4742308
74530142	74530164	2	-	27760321	HT29	viability after 7 days	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	0.54901373167198	[689,538]	[1412,1188,908]	8	hSpCas9	negative selection	4825767
74530303	74530325	2	+	27760321	HT29	viability after 7 days	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	-0.3215898574914868	[597,466]	[726,509,434]	-4	hSpCas9	negative selection	4825768
74530433	74530455	2	-	27760321	HT29	viability after 7 days	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-0.2486667686370111	[505,394]	[590,410,474]	-4	hSpCas9	negative selection	4825769
74530498	74530520	2	+	27760321	HT29	viability after 7 days	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	1.3927282027320023	[384,300]	[1449,836,1224]	9	hSpCas9	negative selection	4825770
74530634	74530656	2	+	27760321	HT29	viability after 7 days	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	0.27188773849234854	[363,283]	[332,841,314]	4	hSpCas9	negative selection	4825771
74530142	74530164	2	-	27760321	HT29	viability after 25 days	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	-0.03329744043869631	[689,538]	[549,505,1047]	0	hSpCas9	negative selection	4909230
74530303	74530325	2	+	27760321	HT29	viability after 25 days	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	-0.32917789432588984	[597,466]	[319,510,648]	-3	hSpCas9	negative selection	4909231
74530433	74530455	2	-	27760321	HT29	viability after 25 days	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-0.8545956042563929	[505,394]	[431,191,212]	-6	hSpCas9	negative selection	4909232
74530498	74530520	2	+	27760321	HT29	viability after 25 days	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	0.8758466226912477	[384,300]	[694,594,885]	8	hSpCas9	negative selection	4909233
74530634	74530656	2	+	27760321	HT29	viability after 25 days	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.17287435096592071	[363,283]	[523,210,226]	-2	hSpCas9	negative selection	4909234
74530142	74530164	2	-	27760321	HT29	viability after 22 days	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	0.43004289462354606	[689,538]	[678,1024,1176]	4	hSpCas9	negative selection	4992693
74530303	74530325	2	+	27760321	HT29	viability after 22 days	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	-0.28478589045646935	[597,466]	[407,461,649]	-3	hSpCas9	negative selection	4992694
74530433	74530455	2	-	27760321	HT29	viability after 22 days	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-0.4912241635765421	[505,394]	[508,309,287]	-4	hSpCas9	negative selection	4992695
74530498	74530520	2	+	27760321	HT29	viability after 22 days	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	0.9139944947687927	[384,300]	[1059,657,512]	9	hSpCas9	negative selection	4992696
74530634	74530656	2	+	27760321	HT29	viability after 22 days	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	0.14196900993019237	[363,283]	[536,337,360]	1	hSpCas9	negative selection	4992697
74530142	74530164	2	-	27760321	HT29	viability after 19 days	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	0.49251125122746	[689,538]	[1013,1035,920]	5	hSpCas9	negative selection	5076156
74530303	74530325	2	+	27760321	HT29	viability after 19 days	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	-0.2852532325955978	[597,466]	[464,226,791]	-3	hSpCas9	negative selection	5076157
74530433	74530455	2	-	27760321	HT29	viability after 19 days	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-0.8682292043634876	[505,394]	[586,210,87]	-6	hSpCas9	negative selection	5076158
74530498	74530520	2	+	27760321	HT29	viability after 19 days	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	1.0332323435707236	[384,300]	[796,790,818]	9	hSpCas9	negative selection	5076159
74530634	74530656	2	+	27760321	HT29	viability after 19 days	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.7462831328648878	[363,283]	[252,301,114]	-5	hSpCas9	negative selection	5076160
74530142	74530164	2	-	27760321	HT29	viability after 16 days	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	0.37671775994147627	[689,538]	[1103,620,979]	4	hSpCas9	negative selection	5159619
74530303	74530325	2	+	27760321	HT29	viability after 16 days	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	-0.3250046602428729	[597,466]	[400,502,514]	-3	hSpCas9	negative selection	5159620
74530433	74530455	2	-	27760321	HT29	viability after 16 days	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-0.5518234043980152	[505,394]	[611,257,188]	-5	hSpCas9	negative selection	5159621
74530498	74530520	2	+	27760321	HT29	viability after 16 days	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	1.035027353207247	[384,300]	[1113,600,679]	9	hSpCas9	negative selection	5159622
74530634	74530656	2	+	27760321	HT29	viability after 16 days	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.046161444081732006	[363,283]	[591,232,253]	0	hSpCas9	negative selection	5159623
74530142	74530164	2	-	27760321	HT29	viability after 13 days	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	0.7386672097782622	[689,538]	[1432,978,1157]	8	hSpCas9	negative selection	5243082
74530303	74530325	2	+	27760321	HT29	viability after 13 days	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	0.12683740100570096	[597,466]	[678,592,746]	1	hSpCas9	negative selection	5243083
74530433	74530455	2	-	27760321	HT29	viability after 13 days	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-0.36955148888526723	[505,394]	[296,447,464]	-4	hSpCas9	negative selection	5243084
74530498	74530520	2	+	27760321	HT29	viability after 13 days	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	0.6858381406476504	[384,300]	[575,643,696]	8	hSpCas9	negative selection	5243085
74530634	74530656	2	+	27760321	HT29	viability after 13 days	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	0.1101861229160998	[363,283]	[482,364,370]	1	hSpCas9	negative selection	5243086
74530142	74530164	2	-	27760321	HT29	viability after 10 days	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	0.49309646227761317	[689,538]	[1304,1087,851]	6	hSpCas9	negative selection	5326545
74530303	74530325	2	+	27760321	HT29	viability after 10 days	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	-0.367550680833432	[597,466]	[596,619,335]	-5	hSpCas9	negative selection	5326546
74530433	74530455	2	-	27760321	HT29	viability after 10 days	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-0.2917898142588609	[505,394]	[548,471,359]	-4	hSpCas9	negative selection	5326547
74530498	74530520	2	+	27760321	HT29	viability after 10 days	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	1.0697116346871591	[384,300]	[940,1022,739]	9	hSpCas9	negative selection	5326548
74530634	74530656	2	+	27760321	HT29	viability after 10 days	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	0.7739734589477301	[363,283]	[752,622,696]	9	hSpCas9	negative selection	5326549
74530142	74530164	2	-	27760321	MOLM13	viability	CATAAGTCACTCGGGCCCGGGG	HTRA2	ENSG00000115317	-0.2721710533888939	[906,689]	[576,193]	-2	hSpCas9	negative selection	5410008
74530303	74530325	2	+	27760321	MOLM13	viability	TGGAACCCGTTCGCGCGCGTGG	HTRA2	ENSG00000115317	-1.4562950366547365	[745,597]	[91,175]	-7	hSpCas9	negative selection	5410009
74530433	74530455	2	-	27760321	MOLM13	viability	TGAAGTTGTACTGACTCCGGGG	HTRA2	ENSG00000115317	-0.45715923207577824	[626,505]	[304,168]	-3	hSpCas9	negative selection	5410010
74530498	74530520	2	+	27760321	MOLM13	viability	CGAGATCCTGGACCGGTAATGG	HTRA2	ENSG00000115317	-1.1733456711541128	[561,384]	[109,122]	-6	hSpCas9	negative selection	5410011
74530634	74530656	2	+	27760321	MOLM13	viability	GCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-1.2070351663253924	[439,363]	[86,106]	-6	hSpCas9	negative selection	5410012
74529484	74529507	2	+	27661255	K562	viability	GCAGTCACCCGGAAGCCTGGGGG	HTRA2	ENSG00000115317	-0.20932092240766578	[731,665]	[567,411]	-6	dCas9-KRAB	negative selection	5464460
74529504	74529527	2	+	27661255	K562	viability	GGGCGAGAGGCGAAGTGGTCAGG	HTRA2	ENSG00000115317	0.08753308419540193	[783,902]	[786,651]	3	dCas9-KRAB	negative selection	5464461
74529663	74529686	2	-	27661255	K562	viability	GCCGGGCGCGAAAATGGCGGCGG	HTRA2	ENSG00000115317	0.6247398187786044	[275,399]	[351,465]	9	dCas9-KRAB	negative selection	5464464
74529958	74529981	2	+	27661255	K562	viability	GGTGCCGCCTCTGAGTAGGGCGG	HTRA2	ENSG00000115317	0.16852932494218192	[543,601]	[560,472]	6	dCas9-KRAB	negative selection	5485886
74529988	74530011	2	+	27661255	K562	viability	GGCAGCCAAGGCGGAGCTGATGG	HTRA2	ENSG00000115317	0.051934027550635475	[566,645]	[567,443]	1	dCas9-KRAB	negative selection	5485887
74530620	74530643	2	-	27661255	K562	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	0.3519468007414701	[217,273]	[306,200]	9	dCas9-KRAB	negative selection	5485888
74529359	74529382	2	+	27260156	BXPC3	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.0949276682451119	[987]	[881,951,1408,1214]	2	hSpCas9	negative selection	5530031
74529446	74529469	2	-	27260156	BXPC3	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	-0.05124630264216462	[589]	[535,525,578,767]	-1	hSpCas9	negative selection	5530032
74530633	74530656	2	+	27260156	BXPC3	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.11212844945568934	[183]	[192,154,147,218]	-3	hSpCas9	negative selection	5548549
74530938	74530961	2	+	27260156	BXPC3	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.4260493870095158	[587]	[348,464,680,331]	-7	hSpCas9	negative selection	5548550
74531876	74531899	2	+	27260156	BXPC3	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.06171780769732926	[0]	[0,0,0,0]	-1	hSpCas9	negative selection	5548551
74531881	74531904	2	-	27260156	BXPC3	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	0.033309124737474854	[535]	[449,528,554,799]	0	hSpCas9	negative selection	5612807
74530642	74530665	2	-	27260156	BXPC3	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.026231405842991436	[469]	[566,412,402,544]	0	hSpCas9	negative selection	5612808
74531014	74531037	2	-	27260156	BXPC3	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.2509829360763851	[597]	[441,651,401,611]	-5	hSpCas9	negative selection	5612809
74529359	74529382	2	+	27260156	A673	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.07638780288921443	[987]	[1405,1191,1156,1266]	1	hSpCas9	negative selection	5651282
74529446	74529469	2	-	27260156	A673	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.3067325543410426	[589]	[991,770,826,932]	7	hSpCas9	negative selection	5651283
74530633	74530656	2	+	27260156	A673	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.2869961279865143	[183]	[207,178,192,144]	-6	hSpCas9	negative selection	5669800
74530938	74530961	2	+	27260156	A673	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.6331004213195286	[587]	[515,420,466,421]	-9	hSpCas9	negative selection	5669801
74531876	74531899	2	+	27260156	A673	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.2631622979798074	[0]	[0,0,0,0]	-6	hSpCas9	negative selection	5669802
74531881	74531904	2	-	27260156	A673	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.37350572610799115	[535]	[589,525,459,415]	-7	hSpCas9	negative selection	5734058
74530642	74530665	2	-	27260156	A673	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.33132568318929584	[469]	[570,417,369,449]	-7	hSpCas9	negative selection	5734059
74531014	74531037	2	-	27260156	A673	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.9530445522610346	[597]	[528,292,232,453]	-9	hSpCas9	negative selection	5734060
74529359	74529382	2	+	27260156	A375	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.28847045308382846	[987]	[1309,1773,1335,1277]	4	hSpCas9	negative selection	5772533
74529446	74529469	2	-	27260156	A375	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.20736235705853506	[589]	[697,786,1002,700]	3	hSpCas9	negative selection	5772534
74530633	74530656	2	+	27260156	A375	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.21805982907033306	[183]	[172,133,209,210]	-3	hSpCas9	negative selection	5791051
74530938	74530961	2	+	27260156	A375	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.7261243670977386	[587]	[323,440,527,373]	-7	hSpCas9	negative selection	5791052
74531876	74531899	2	+	27260156	A375	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.22260698094002684	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	5791053
74531881	74531904	2	-	27260156	A375	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.09800169345415055	[535]	[565,571,644,555]	-1	hSpCas9	negative selection	5855309
74530642	74530665	2	-	27260156	A375	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	0.08532593549281733	[469]	[491,530,736,561]	1	hSpCas9	negative selection	5855310
74531014	74531037	2	-	27260156	A375	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.6440558515593435	[597]	[330,515,400,535]	-7	hSpCas9	negative selection	5855311
74529359	74529382	2	+	27260156	COLO741	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.15077603225610692	[987]	[1258,1578,1354]	3	hSpCas9	negative selection	5893784
74529446	74529469	2	-	27260156	COLO741	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.3272977619187764	[589]	[1307,885,690]	6	hSpCas9	negative selection	5893785
74530633	74530656	2	+	27260156	COLO741	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.22643631715550017	[183]	[213,167,219]	-5	hSpCas9	negative selection	5912302
74530938	74530961	2	+	27260156	COLO741	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.34776599717830803	[587]	[493,526,729]	-6	hSpCas9	negative selection	5912303
74531876	74531899	2	+	27260156	COLO741	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.3524737808476335	[0]	[0,0,0]	-6	hSpCas9	negative selection	5912304
74531881	74531904	2	-	27260156	COLO741	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.08883059734723968	[535]	[689,624,620]	-2	hSpCas9	negative selection	5976560
74530642	74530665	2	-	27260156	COLO741	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.09231233572573709	[469]	[554,639,497]	-2	hSpCas9	negative selection	5976561
74531014	74531037	2	-	27260156	COLO741	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.5256279479552981	[597]	[494,629,467]	-8	hSpCas9	negative selection	5976562
74529359	74529382	2	+	27260156	CAL120	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	-0.09032618897436795	[987]	[925,1202,1297]	-1	hSpCas9	negative selection	6015035
74529446	74529469	2	-	27260156	CAL120	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.06869068136177425	[589]	[688,1035,575]	1	hSpCas9	negative selection	6015036
74530633	74530656	2	+	27260156	CAL120	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.7016056879147032	[183]	[142,102,175]	-7	hSpCas9	negative selection	6033553
74530938	74530961	2	+	27260156	CAL120	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.5004868399090083	[587]	[573,581,405]	-6	hSpCas9	negative selection	6033554
74531876	74531899	2	+	27260156	CAL120	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.31522623407729533	[0]	[0,0,0]	-4	hSpCas9	negative selection	6033555
74531881	74531904	2	-	27260156	CAL120	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.24933624344928954	[535]	[467,687,513]	-4	hSpCas9	negative selection	6097811
74530642	74530665	2	-	27260156	CAL120	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	0.301021428418978	[469]	[625,847,673]	4	hSpCas9	negative selection	6097812
74531014	74531037	2	-	27260156	CAL120	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.39549898958455526	[597]	[668,563,480]	-5	hSpCas9	negative selection	6097813
74529359	74529382	2	+	27260156	CADOES1	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.31287848176019994	[987]	[1049,1143,1127,1247]	5	hSpCas9	negative selection	6136286
74529446	74529469	2	-	27260156	CADOES1	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.16805343488111224	[589]	[593,691,724,448]	3	hSpCas9	negative selection	6136287
74530633	74530656	2	+	27260156	CADOES1	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-1.1899493473882599	[183]	[89,56,76,75]	-9	hSpCas9	negative selection	6154804
74530938	74530961	2	+	27260156	CADOES1	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.9155451354290949	[587]	[244,279,287,348]	-9	hSpCas9	negative selection	6154805
74531876	74531899	2	+	27260156	CADOES1	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.1046074123573355	[0]	[0,0,0,0]	1	hSpCas9	negative selection	6154806
74531881	74531904	2	-	27260156	CADOES1	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.21341429049373892	[535]	[521,387,265,547]	-4	hSpCas9	negative selection	6219062
74530642	74530665	2	-	27260156	CADOES1	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.45223456200153955	[469]	[278,310,395,290]	-7	hSpCas9	negative selection	6219063
74531014	74531037	2	-	27260156	CADOES1	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.7844435418745155	[597]	[315,354,340,277]	-8	hSpCas9	negative selection	6219064
74529359	74529382	2	+	27260156	EWS502	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.2929608787302489	[987]	[1103,1249,1488,1307]	5	hSpCas9	negative selection	6257537
74529446	74529469	2	-	27260156	EWS502	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.3440499730945326	[589]	[541,976,945,724]	6	hSpCas9	negative selection	6257538
74530633	74530656	2	+	27260156	EWS502	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.7445404857074616	[183]	[95,107,164,97]	-8	hSpCas9	negative selection	6276055
74530938	74530961	2	+	27260156	EWS502	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.4765125064712977	[587]	[403,440,518,429]	-7	hSpCas9	negative selection	6276056
74531876	74531899	2	+	27260156	EWS502	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.08156866895534698	[0]	[0,0,0,0]	-1	hSpCas9	negative selection	6276057
74531881	74531904	2	-	27260156	EWS502	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.4894331266607688	[535]	[257,480,452,441]	-7	hSpCas9	negative selection	6340313
74530642	74530665	2	-	27260156	EWS502	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.42589648260582624	[469]	[395,378,472,219]	-6	hSpCas9	negative selection	6340314
74531014	74531037	2	-	27260156	EWS502	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.7082858194414836	[597]	[309,371,404,478]	-8	hSpCas9	negative selection	6340315
74529359	74529382	2	+	27260156	EW8	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.21258136666260974	[987]	[985,855,810,1080]	4	hSpCas9	negative selection	6378788
74529446	74529469	2	-	27260156	EW8	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.34460735322127994	[589]	[883,484,499,605]	6	hSpCas9	negative selection	6378789
74530633	74530656	2	+	27260156	EW8	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-1.4125408652137756	[183]	[78,34,63,46]	-9	hSpCas9	negative selection	6397306
74530938	74530961	2	+	27260156	EW8	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.9642741914698802	[587]	[337,262,141,260]	-9	hSpCas9	negative selection	6397307
74531876	74531899	2	+	27260156	EW8	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.30430985650646214	[0]	[0,0,0,0]	5	hSpCas9	negative selection	6397308
74531881	74531904	2	-	27260156	EW8	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.4942173542965331	[535]	[386,317,275,265]	-7	hSpCas9	negative selection	6461564
74530642	74530665	2	-	27260156	EW8	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.8631648000343352	[469]	[227,234,102,290]	-9	hSpCas9	negative selection	6461565
74531014	74531037	2	-	27260156	EW8	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-1.3543376709949069	[597]	[243,206,74,256]	-9	hSpCas9	negative selection	6461566
74529359	74529382	2	+	27260156	CORL105	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.020785537076229765	[987]	[1096,1227,1432,972]	0	hSpCas9	negative selection	6500039
74529446	74529469	2	-	27260156	CORL105	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.06471627985719658	[589]	[733,709,828,633]	1	hSpCas9	negative selection	6500040
74530633	74530656	2	+	27260156	CORL105	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.10364555371333983	[183]	[186,165,213,236]	-2	hSpCas9	negative selection	6518557
74530938	74530961	2	+	27260156	CORL105	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.7438268453231018	[587]	[352,428,519,356]	-8	hSpCas9	negative selection	6518558
74531876	74531899	2	+	27260156	CORL105	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.22721281181091513	[0]	[0,0,0,0]	-4	hSpCas9	negative selection	6518559
74531881	74531904	2	-	27260156	CORL105	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.6294991513391012	[535]	[278,425,629,317]	-8	hSpCas9	negative selection	6582815
74530642	74530665	2	-	27260156	CORL105	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.1893727819638349	[469]	[404,346,606,589]	-4	hSpCas9	negative selection	6582816
74531014	74531037	2	-	27260156	CORL105	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.6726225232719951	[597]	[298,382,650,452]	-8	hSpCas9	negative selection	6582817
74529359	74529382	2	+	27260156	HS294T	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.21451147781305835	[987]	[402,507,409,453]	3	hSpCas9	negative selection	6621290
74529446	74529469	2	-	27260156	HS294T	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.10588356177199332	[589]	[174,219,222,395]	1	hSpCas9	negative selection	6621291
74530633	74530656	2	+	27260156	HS294T	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-1.1756722511250106	[183]	[21,27,39,37]	-9	hSpCas9	negative selection	6639808
74530938	74530961	2	+	27260156	HS294T	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	0.18262325728197776	[587]	[378,96,315,227]	2	hSpCas9	negative selection	6639809
74531876	74531899	2	+	27260156	HS294T	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	1.3721219085074186	[0]	[0,0,0,0]	9	hSpCas9	negative selection	6639810
74531881	74531904	2	-	27260156	HS294T	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.019129531630635355	[535]	[139,288,170,223]	0	hSpCas9	negative selection	6704066
74530642	74530665	2	-	27260156	HS294T	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.5962037186381909	[469]	[91,143,82,171]	-7	hSpCas9	negative selection	6704067
74531014	74531037	2	-	27260156	HS294T	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	0.1305430376104872	[597]	[131,375,303,197]	1	hSpCas9	negative selection	6704068
74529359	74529382	2	+	27260156	HCC44	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.1736705549680544	[987]	[1378,958,1407,1360]	2	hSpCas9	negative selection	6742541
74529446	74529469	2	-	27260156	HCC44	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.33099666162011526	[589]	[931,597,811,1039]	5	hSpCas9	negative selection	6742542
74530633	74530656	2	+	27260156	HCC44	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.5297201212441383	[183]	[150,117,158,153]	-7	hSpCas9	negative selection	6761059
74530938	74530961	2	+	27260156	HCC44	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.27461434732856466	[587]	[784,418,424,582]	-4	hSpCas9	negative selection	6761060
74531876	74531899	2	+	27260156	HCC44	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.17453351620550883	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	6761061
74531881	74531904	2	-	27260156	HCC44	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	0.4072595317358816	[535]	[683,783,1014,755]	6	hSpCas9	negative selection	6825317
74530642	74530665	2	-	27260156	HCC44	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.2640932457715941	[469]	[506,457,546,281]	-4	hSpCas9	negative selection	6825318
74531014	74531037	2	-	27260156	HCC44	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.5327477478317515	[597]	[347,430,779,358]	-7	hSpCas9	negative selection	6825319
74529359	74529382	2	+	27260156	G402	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.46333033379106214	[987]	[1498,1655,2009,1462]	6	hSpCas9	negative selection	6863792
74529446	74529469	2	-	27260156	G402	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.20280819738505623	[589]	[1067,767,970,548]	2	hSpCas9	negative selection	6863793
74530633	74530656	2	+	27260156	G402	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.5658033672060305	[183]	[122,43,409,24]	-6	hSpCas9	negative selection	6882310
74530938	74530961	2	+	27260156	G402	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.5416034591132945	[587]	[402,557,346,644]	-6	hSpCas9	negative selection	6882311
74531876	74531899	2	+	27260156	G402	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.28565990241013317	[0]	[0,0,0,0]	-4	hSpCas9	negative selection	6882312
74531881	74531904	2	-	27260156	G402	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.49103040984339397	[535]	[870,323,313,403]	-6	hSpCas9	negative selection	6946568
74530642	74530665	2	-	27260156	G402	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.5309835468701326	[469]	[319,754,191,331]	-6	hSpCas9	negative selection	6946569
74531014	74531037	2	-	27260156	G402	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.6011454474727269	[597]	[396,927,424,199]	-6	hSpCas9	negative selection	6946570
74529359	74529382	2	+	27260156	L33	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.0661132915400755	[987]	[931,455,546,1221]	1	hSpCas9	negative selection	6985043
74529446	74529469	2	-	27260156	L33	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.4553693855834782	[589]	[842,279,638,693]	8	hSpCas9	negative selection	6985044
74530633	74530656	2	+	27260156	L33	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.2056429205206718	[183]	[129,74,95,172]	-5	hSpCas9	negative selection	7003561
74530938	74530961	2	+	27260156	L33	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.24865039598905264	[587]	[386,227,369,450]	-5	hSpCas9	negative selection	7003562
74531876	74531899	2	+	27260156	L33	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.5883332593072037	[0]	[0,0,0,0]	9	hSpCas9	negative selection	7003563
74531881	74531904	2	-	27260156	L33	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.19887137368543456	[535]	[369,225,305,461]	-4	hSpCas9	negative selection	7067819
74530642	74530665	2	-	27260156	L33	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.180369113345176	[469]	[438,144,281,416]	-4	hSpCas9	negative selection	7067820
74531014	74531037	2	-	27260156	L33	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.8610872975169908	[597]	[323,154,188,313]	-9	hSpCas9	negative selection	7067821
74529359	74529382	2	+	27260156	K562	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.37769556627627554	[987]	[1375,1062,892,1224]	5	hSpCas9	negative selection	7106294
74529446	74529469	2	-	27260156	K562	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.06913950329198537	[589]	[684,385,639,492]	0	hSpCas9	negative selection	7106295
74530633	74530656	2	+	27260156	K562	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-1.5013897329693053	[183]	[84,53,49,44]	-9	hSpCas9	negative selection	7124812
74530938	74530961	2	+	27260156	K562	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.8677751882989972	[587]	[253,177,375,321]	-7	hSpCas9	negative selection	7124813
74531876	74531899	2	+	27260156	K562	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.1738498320762858	[0]	[0,0,0,0]	2	hSpCas9	negative selection	7124814
74531881	74531904	2	-	27260156	K562	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.42989279557114446	[535]	[317,503,269,326]	-5	hSpCas9	negative selection	7189070
74530642	74530665	2	-	27260156	K562	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-1.136801078227751	[469]	[297,207,83,178]	-8	hSpCas9	negative selection	7189071
74531014	74531037	2	-	27260156	K562	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.8916965541733647	[597]	[206,289,309,324]	-7	hSpCas9	negative selection	7189072
74529359	74529382	2	+	27260156	HT29	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.0603799250715793	[987]	[1431,1208,1355,1039]	1	hSpCas9	negative selection	7227545
74529446	74529469	2	-	27260156	HT29	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.1576690960109688	[589]	[806,885,796,721]	3	hSpCas9	negative selection	7227546
74530633	74530656	2	+	27260156	HT29	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.2906417128213352	[183]	[231,176,173,153]	-5	hSpCas9	negative selection	7246063
74530938	74530961	2	+	27260156	HT29	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.22151237479839142	[587]	[590,667,661,538]	-4	hSpCas9	negative selection	7246064
74531876	74531899	2	+	27260156	HT29	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.27901894800515237	[0]	[0,0,0,0]	-5	hSpCas9	negative selection	7246065
74531881	74531904	2	-	27260156	HT29	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.34250901536014433	[535]	[522,477,620,436]	-6	hSpCas9	negative selection	7310321
74530642	74530665	2	-	27260156	HT29	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.2530126874488628	[469]	[533,451,458,471]	-5	hSpCas9	negative selection	7310322
74531014	74531037	2	-	27260156	HT29	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.3559887007696	[597]	[501,569,632,558]	-6	hSpCas9	negative selection	7310323
74529359	74529382	2	+	27260156	MHHES1	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.2788865146471251	[987]	[1358,1470,1367,1215]	5	hSpCas9	negative selection	7348796
74529446	74529469	2	-	27260156	MHHES1	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.21926531023297252	[589]	[705,794,955,644]	4	hSpCas9	negative selection	7348797
74530633	74530656	2	+	27260156	MHHES1	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.07448373958225885	[183]	[171,144,256,199]	-1	hSpCas9	negative selection	7367314
74530938	74530961	2	+	27260156	MHHES1	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.2475838059720123	[587]	[691,514,694,372]	-5	hSpCas9	negative selection	7367315
74531876	74531899	2	+	27260156	MHHES1	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.1630968580950416	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	7367316
74531881	74531904	2	-	27260156	MHHES1	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.2853142689875292	[535]	[440,404,689,433]	-5	hSpCas9	negative selection	7431572
74530642	74530665	2	-	27260156	MHHES1	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.15519004651053617	[469]	[456,820,409,280]	-3	hSpCas9	negative selection	7431573
74531014	74531037	2	-	27260156	MHHES1	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.44522177569680427	[597]	[399,608,538,433]	-7	hSpCas9	negative selection	7431574
74529359	74529382	2	+	27260156	MEWO	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.07599553440964235	[987]	[1220,884,864]	1	hSpCas9	negative selection	7470047
74529446	74529469	2	-	27260156	MEWO	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.013819640124156207	[589]	[680,500,513]	0	hSpCas9	negative selection	7470048
74530633	74530656	2	+	27260156	MEWO	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.34497027166221605	[183]	[179,172,61]	-6	hSpCas9	negative selection	7488565
74530938	74530961	2	+	27260156	MEWO	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.5659176403032189	[587]	[323,480,299]	-8	hSpCas9	negative selection	7488566
74531876	74531899	2	+	27260156	MEWO	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.09620936660807722	[0]	[0,0,0]	2	hSpCas9	negative selection	7488567
74531881	74531904	2	-	27260156	MEWO	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.2999191456105118	[535]	[360,394,456]	-6	hSpCas9	negative selection	7552823
74530642	74530665	2	-	27260156	MEWO	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	0.30787024619944714	[469]	[555,560,517]	6	hSpCas9	negative selection	7552824
74531014	74531037	2	-	27260156	MEWO	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.8718045926906909	[597]	[407,290,237]	-9	hSpCas9	negative selection	7552825
74529359	74529382	2	+	27260156	LNCAPCLONEFGC	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.27512267950365565	[987]	[1198,843,1258,1068]	4	hSpCas9	negative selection	7591298
74529446	74529469	2	-	27260156	LNCAPCLONEFGC	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.399980932783815	[589]	[751,582,822,686]	6	hSpCas9	negative selection	7591299
74530633	74530656	2	+	27260156	LNCAPCLONEFGC	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.9045008365936091	[183]	[31,112,104,107]	-8	hSpCas9	negative selection	7609816
74530938	74530961	2	+	27260156	LNCAPCLONEFGC	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-1.1641613565751912	[587]	[122,261,249,317]	-9	hSpCas9	negative selection	7609817
74531876	74531899	2	+	27260156	LNCAPCLONEFGC	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.14289828313858877	[0]	[0,0,0,0]	2	hSpCas9	negative selection	7609818
74531881	74531904	2	-	27260156	LNCAPCLONEFGC	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.1167543725757194	[535]	[510,435,444,397]	-2	hSpCas9	negative selection	7674074
74530642	74530665	2	-	27260156	LNCAPCLONEFGC	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-1.5745964931732155	[469]	[96,203,98,161]	-9	hSpCas9	negative selection	7674075
74531014	74531037	2	-	27260156	LNCAPCLONEFGC	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-1.2761904095099112	[597]	[285,191,173,235]	-9	hSpCas9	negative selection	7674076
74529359	74529382	2	+	27260156	PANC0327	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.4036582583111388	[987]	[1173,724,1711,1090]	6	hSpCas9	negative selection	7712549
74529446	74529469	2	-	27260156	PANC0327	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.23807057677299298	[589]	[823,482,746,452]	3	hSpCas9	negative selection	7712550
74530633	74530656	2	+	27260156	PANC0327	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	0.45386546555345486	[183]	[286,104,261,261]	6	hSpCas9	negative selection	7731067
74530938	74530961	2	+	27260156	PANC0327	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.6231571338534156	[587]	[565,238,353,228]	-7	hSpCas9	negative selection	7731068
74531876	74531899	2	+	27260156	PANC0327	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.17097580133514256	[0]	[0,0,0,0]	2	hSpCas9	negative selection	7731069
74531881	74531904	2	-	27260156	PANC0327	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.2790704007593098	[535]	[583,384,296,319]	-4	hSpCas9	negative selection	7795325
74530642	74530665	2	-	27260156	PANC0327	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	0.04717451639212151	[469]	[429,364,513,424]	0	hSpCas9	negative selection	7795326
74531014	74531037	2	-	27260156	PANC0327	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.5144817921001976	[597]	[317,326,509,333]	-6	hSpCas9	negative selection	7795327
74529359	74529382	2	+	27260156	NCIH2009	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	-0.060693057233193404	[987]	[1619,1098,1311]	-1	hSpCas9	negative selection	7833800
74529446	74529469	2	-	27260156	NCIH2009	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	-0.34076898221821195	[589]	[757,527,688]	-4	hSpCas9	negative selection	7833801
74530633	74530656	2	+	27260156	NCIH2009	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-1.9530915382828016	[183]	[87,84,29]	-9	hSpCas9	negative selection	7852318
74530938	74530961	2	+	27260156	NCIH2009	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-2.1499573799017604	[587]	[202,269,83]	-9	hSpCas9	negative selection	7852319
74531876	74531899	2	+	27260156	NCIH2009	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.4816251237464222	[0]	[0,0,0]	-6	hSpCas9	negative selection	7852320
74531881	74531904	2	-	27260156	NCIH2009	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.09066644481435394	[535]	[847,603,686]	-1	hSpCas9	negative selection	7916576
74530642	74530665	2	-	27260156	NCIH2009	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-2.3229151123044516	[469]	[149,142,103]	-9	hSpCas9	negative selection	7916577
74531014	74531037	2	-	27260156	NCIH2009	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-1.02681933539391	[597]	[287,373,543]	-8	hSpCas9	negative selection	7916578
74529359	74529382	2	+	27260156	NCIH1373	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.3165267525822002	[987]	[1539,1103,1482,377]	3	hSpCas9	negative selection	7955051
74529446	74529469	2	-	27260156	NCIH1373	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	-0.04103660202719661	[589]	[588,615,645,187]	0	hSpCas9	negative selection	7955052
74530633	74530656	2	+	27260156	NCIH1373	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-1.9132506991472131	[183]	[72,19,81,12]	-9	hSpCas9	negative selection	7973569
74530938	74530961	2	+	27260156	NCIH1373	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.6147860704389293	[587]	[347,492,501,91]	-6	hSpCas9	negative selection	7973570
74531876	74531899	2	+	27260156	NCIH1373	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.5801096359471138	[0]	[0,0,0,0]	6	hSpCas9	negative selection	7973571
74531881	74531904	2	-	27260156	NCIH1373	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	0.15829760789637043	[535]	[381,441,579,339]	1	hSpCas9	negative selection	8037827
74530642	74530665	2	-	27260156	NCIH1373	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.4176083705020795	[469]	[293,427,433,104]	-4	hSpCas9	negative selection	8037828
74531014	74531037	2	-	27260156	NCIH1373	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.6799734388845906	[597]	[429,379,419,117]	-6	hSpCas9	negative selection	8037829
74529359	74529382	2	+	27260156	PATU8902	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.7500961143586409	[987]	[3286,2371,1440,2357]	7	hSpCas9	negative selection	8076302
74529446	74529469	2	-	27260156	PATU8902	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.978115546967238	[589]	[1798,1687,1150,1986]	9	hSpCas9	negative selection	8076303
74530633	74530656	2	+	27260156	PATU8902	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.3038697344339818	[183]	[337,200,55,279]	-3	hSpCas9	negative selection	8094820
74530938	74530961	2	+	27260156	PATU8902	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.4646587402139052	[587]	[458,427,867,536]	-4	hSpCas9	negative selection	8094821
74531876	74531899	2	+	27260156	PATU8902	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.47507721586162077	[0]	[0,0,0,0]	-5	hSpCas9	negative selection	8094822
74531881	74531904	2	-	27260156	PATU8902	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.024646446774384073	[535]	[634,315,874,1111]	0	hSpCas9	negative selection	8159078
74530642	74530665	2	-	27260156	PATU8902	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	0.25248610544432587	[469]	[430,924,594,1273]	2	hSpCas9	negative selection	8159079
74531014	74531037	2	-	27260156	PATU8902	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.7234483550566189	[597]	[842,643,182,411]	-6	hSpCas9	negative selection	8159080
74529359	74529382	2	+	27260156	PANC1	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.3919289283835974	[987]	[1250,1376,1004,889]	6	hSpCas9	negative selection	8197553
74529446	74529469	2	-	27260156	PANC1	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.15032908867475264	[589]	[625,624,459,542]	2	hSpCas9	negative selection	8197554
74530633	74530656	2	+	27260156	PANC1	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-1.5900144079184013	[183]	[44,50,66,46]	-9	hSpCas9	negative selection	8216071
74530938	74530961	2	+	27260156	PANC1	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-1.8677940205200354	[587]	[66,200,140,153]	-9	hSpCas9	negative selection	8216072
74531876	74531899	2	+	27260156	PANC1	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.22557163962344795	[0]	[0,0,0,0]	3	hSpCas9	negative selection	8216073
74531881	74531904	2	-	27260156	PANC1	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.703892482675392	[535]	[256,370,384,153]	-7	hSpCas9	negative selection	8280329
74530642	74530665	2	-	27260156	PANC1	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.9639424947686007	[469]	[207,254,184,188]	-8	hSpCas9	negative selection	8280330
74531014	74531037	2	-	27260156	PANC1	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-1.5338024201250948	[597]	[124,331,210,86]	-9	hSpCas9	negative selection	8280331
74529359	74529382	2	+	27260156	PANC0813	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.17338553646695942	[987]	[1527,1287,1157,1279]	3	hSpCas9	negative selection	8318804
74529446	74529469	2	-	27260156	PANC0813	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	-0.04564308811798379	[589]	[749,573,676,689]	0	hSpCas9	negative selection	8318805
74530633	74530656	2	+	27260156	PANC0813	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.9986444705908779	[183]	[114,115,92,108]	-8	hSpCas9	negative selection	8337322
74530938	74530961	2	+	27260156	PANC0813	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.659432160035702	[587]	[460,544,341,403]	-7	hSpCas9	negative selection	8337323
74531876	74531899	2	+	27260156	PANC0813	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.23161252818376	[0]	[0,0,0,0]	-4	hSpCas9	negative selection	8337324
74531881	74531904	2	-	27260156	PANC0813	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.08067504915337001	[535]	[534,611,562,660]	-1	hSpCas9	negative selection	8401580
74530642	74530665	2	-	27260156	PANC0813	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.4270348383819124	[469]	[434,375,470,364]	-6	hSpCas9	negative selection	8401581
74531014	74531037	2	-	27260156	PANC0813	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.5115691358866181	[597]	[510,546,550,369]	-6	hSpCas9	negative selection	8401582
74529359	74529382	2	+	27260156	RDES	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.2684316601909431	[987]	[1069,1330,1509,1636]	4	hSpCas9	negative selection	8440055
74529446	74529469	2	-	27260156	RDES	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.36357409541260616	[589]	[826,751,1046,863]	6	hSpCas9	negative selection	8440056
74530633	74530656	2	+	27260156	RDES	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	0.1899302662129858	[183]	[178,216,239,355]	3	hSpCas9	negative selection	8458573
74530938	74530961	2	+	27260156	RDES	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.34326719631028696	[587]	[460,489,550,651]	-5	hSpCas9	negative selection	8458574
74531876	74531899	2	+	27260156	RDES	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.18942035355372333	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	8458575
74531881	74531904	2	-	27260156	RDES	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.16540584338068856	[535]	[535,530,525,597]	-3	hSpCas9	negative selection	8522831
74530642	74530665	2	-	27260156	RDES	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.08996971631970785	[469]	[329,493,601,657]	-1	hSpCas9	negative selection	8522832
74531014	74531037	2	-	27260156	RDES	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.37380542844022036	[597]	[428,421,611,706]	-6	hSpCas9	negative selection	8522833
74529359	74529382	2	+	27260156	PC3	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.0976387973123718	[987]	[628,1049,1803,1114]	2	hSpCas9	negative selection	8561306
74529446	74529469	2	-	27260156	PC3	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.3837198373572022	[589]	[466,828,1404,666]	7	hSpCas9	negative selection	8561307
74530633	74530656	2	+	27260156	PC3	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.07590822276376752	[183]	[127,152,344,136]	-2	hSpCas9	negative selection	8579824
74530938	74530961	2	+	27260156	PC3	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.6750623121811807	[587]	[304,282,481,431]	-9	hSpCas9	negative selection	8579825
74531876	74531899	2	+	27260156	PC3	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.05753347684474441	[0]	[0,0,0,0]	1	hSpCas9	negative selection	8579826
74531881	74531904	2	-	27260156	PC3	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.2956803791294549	[535]	[250,509,716,407]	-6	hSpCas9	negative selection	8644082
74530642	74530665	2	-	27260156	PC3	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	0.023299938488766474	[469]	[354,477,828,373]	0	hSpCas9	negative selection	8644083
74531014	74531037	2	-	27260156	PC3	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.5750359093409367	[597]	[276,286,778,424]	-8	hSpCas9	negative selection	8644084
74529359	74529382	2	+	27260156	PATU8988T	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.6373997076227111	[987]	[1407,1982,1327,1250]	9	hSpCas9	negative selection	8682557
74529446	74529469	2	-	27260156	PATU8988T	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.2136577588781577	[589]	[542,751,611,753]	3	hSpCas9	negative selection	8682558
74530633	74530656	2	+	27260156	PATU8988T	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	0.534870441326545	[183]	[230,367,181,260]	8	hSpCas9	negative selection	8701075
74530938	74530961	2	+	27260156	PATU8988T	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.25780330213280656	[587]	[339,596,565,401]	-4	hSpCas9	negative selection	8701076
74531876	74531899	2	+	27260156	PATU8988T	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.04952519822641044	[0]	[0,0,0,0]	0	hSpCas9	negative selection	8701077
74531881	74531904	2	-	27260156	PATU8988T	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.3965791969879653	[535]	[430,468,183,508]	-6	hSpCas9	negative selection	8765333
74530642	74530665	2	-	27260156	PATU8988T	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.08640599759587499	[469]	[553,401,491,244]	-1	hSpCas9	negative selection	8765334
74531014	74531037	2	-	27260156	PATU8988T	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.5505643094799048	[597]	[294,374,554,344]	-7	hSpCas9	negative selection	8765335
74529359	74529382	2	+	27260156	T47D	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.20165511612276488	[987]	[1428,1069,1372,1447]	4	hSpCas9	negative selection	8803808
74529446	74529469	2	-	27260156	T47D	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.2403137720917044	[589]	[741,857,846,794]	5	hSpCas9	negative selection	8803809
74530633	74530656	2	+	27260156	T47D	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.026243880523578955	[183]	[222,126,226,273]	0	hSpCas9	negative selection	8822326
74530938	74530961	2	+	27260156	T47D	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.2838185271029045	[587]	[555,593,518,579]	-6	hSpCas9	negative selection	8822327
74531876	74531899	2	+	27260156	T47D	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.2201891943612022	[0]	[0,0,0,0]	-5	hSpCas9	negative selection	8822328
74531881	74531904	2	-	27260156	T47D	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.2084188650298876	[535]	[505,544,539,570]	-4	hSpCas9	negative selection	8886584
74530642	74530665	2	-	27260156	T47D	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.04966402224206364	[469]	[516,561,450,585]	-1	hSpCas9	negative selection	8886585
74531014	74531037	2	-	27260156	T47D	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.5186872627181325	[597]	[488,385,489,591]	-8	hSpCas9	negative selection	8886586
74529359	74529382	2	+	27260156	SU8686	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.3231205781330433	[987]	[1175,995,1264,1543]	5	hSpCas9	negative selection	8925059
74529446	74529469	2	-	27260156	SU8686	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.4566182512080654	[589]	[683,797,756,1012]	7	hSpCas9	negative selection	8925060
74530633	74530656	2	+	27260156	SU8686	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-2.0704562680337735	[183]	[40,84,15,21]	-9	hSpCas9	negative selection	8943577
74530938	74530961	2	+	27260156	SU8686	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-1.5682894473164495	[587]	[289,220,109,137]	-9	hSpCas9	negative selection	8943578
74531876	74531899	2	+	27260156	SU8686	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.015103263740369854	[0]	[0,0,0,0]	0	hSpCas9	negative selection	8943579
74531881	74531904	2	-	27260156	SU8686	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.3262677559864824	[535]	[327,385,333,702]	-5	hSpCas9	negative selection	9007835
74530642	74530665	2	-	27260156	SU8686	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-1.3988338818662336	[469]	[220,209,107,150]	-9	hSpCas9	negative selection	9007836
74531014	74531037	2	-	27260156	SU8686	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-1.1119218353824736	[597]	[237,241,162,492]	-8	hSpCas9	negative selection	9007837
74529359	74529382	2	+	27260156	SKES1	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.2103108088617598	[987]	[1324,1423,972,915]	4	hSpCas9	negative selection	9046310
74529446	74529469	2	-	27260156	SKES1	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.36356547275025414	[589]	[728,770,776,742]	7	hSpCas9	negative selection	9046311
74530633	74530656	2	+	27260156	SKES1	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.08527154061364128	[183]	[205,170,176,143]	-2	hSpCas9	negative selection	9064828
74530938	74530961	2	+	27260156	SKES1	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.5194652717289738	[587]	[393,406,451,379]	-8	hSpCas9	negative selection	9064829
74531876	74531899	2	+	27260156	SKES1	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.007546427030755254	[0]	[0,0,0,0]	0	hSpCas9	negative selection	9064830
74531881	74531904	2	-	27260156	SKES1	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.165775660290561	[535]	[300,702,475,429]	-4	hSpCas9	negative selection	9129086
74530642	74530665	2	-	27260156	SKES1	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.1582198173319221	[469]	[534,466,364,340]	-3	hSpCas9	negative selection	9129087
74531014	74531037	2	-	27260156	SKES1	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.624792507201583	[597]	[449,507,360,262]	-8	hSpCas9	negative selection	9129088
74529359	74529382	2	+	27260156	TOV112D	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.33196681478101797	[987]	[1150,1917,1088,986]	6	hSpCas9	negative selection	9167561
74529446	74529469	2	-	27260156	TOV112D	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.5097555851781297	[589]	[1179,975,621,652]	8	hSpCas9	negative selection	9167562
74530633	74530656	2	+	27260156	TOV112D	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	0.10077070609868688	[183]	[165,365,210,88]	2	hSpCas9	negative selection	9186079
74530938	74530961	2	+	27260156	TOV112D	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.4233198370304694	[587]	[470,405,382,488]	-7	hSpCas9	negative selection	9186080
74531876	74531899	2	+	27260156	TOV112D	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.0015868904355240687	[0]	[0,0,0,0]	0	hSpCas9	negative selection	9186081
74531881	74531904	2	-	27260156	TOV112D	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	0.004251740164179285	[535]	[633,565,515,453]	0	hSpCas9	negative selection	9250337
74530642	74530665	2	-	27260156	TOV112D	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	0.4031746778047384	[469]	[398,1009,551,604]	7	hSpCas9	negative selection	9250338
74531014	74531037	2	-	27260156	TOV112D	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.4094714871820756	[597]	[436,672,423,325]	-7	hSpCas9	negative selection	9250339
74529359	74529382	2	+	27260156	TC71	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.11942877613726188	[987]	[1030,1133,1026,1433]	3	hSpCas9	negative selection	9288812
74529446	74529469	2	-	27260156	TC71	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.44276954823249065	[589]	[898,827,918,784]	8	hSpCas9	negative selection	9288813
74530633	74530656	2	+	27260156	TC71	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.22520882861637537	[183]	[171,148,137,219]	-6	hSpCas9	negative selection	9307330
74530938	74530961	2	+	27260156	TC71	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.25357249253848885	[587]	[519,416,616,559]	-6	hSpCas9	negative selection	9307331
74531876	74531899	2	+	27260156	TC71	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	-0.10019163119465624	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	9307332
74531881	74531904	2	-	27260156	TC71	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.4184204850003812	[535]	[372,386,424,542]	-8	hSpCas9	negative selection	9371588
74530642	74530665	2	-	27260156	TC71	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.05323658177858249	[469]	[392,506,515,529]	-1	hSpCas9	negative selection	9371589
74531014	74531037	2	-	27260156	TC71	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.534480252423553	[597]	[437,491,505,324]	-9	hSpCas9	negative selection	9371590
74529359	74529382	2	+	27260156	TC32	viability	AACCTGCGAAGGACGCTGTCTGG	HTRA2	ENSG00000115317	0.23063027098735756	[987]	[1039,931,1327,1096]	4	hSpCas9	negative selection	9410063
74529446	74529469	2	-	27260156	TC32	viability	CTGCTGCTCTACGCGCCAGTCGG	HTRA2	ENSG00000115317	0.055651706702675885	[589]	[441,543,729,610]	1	hSpCas9	negative selection	9410064
74530633	74530656	2	+	27260156	TC32	viability	CGCGAGGTCCCTATCTCGAACGG	HTRA2	ENSG00000115317	-0.704746401148109	[183]	[101,16,224,131]	-8	hSpCas9	negative selection	9428581
74530938	74530961	2	+	27260156	TC32	viability	CGCTCAGCTGATGTCCGGCAAGG	HTRA2	ENSG00000115317	-0.2347823040045668	[587]	[497,364,669,381]	-4	hSpCas9	negative selection	9428582
74531876	74531899	2	+	27260156	TC32	viability	GGGTCCCAGCGGCGCTACATTGG	HTRA2	ENSG00000115317	0.11232540807230862	[0]	[0,0,0,0]	2	hSpCas9	negative selection	9428583
74531881	74531904	2	-	27260156	TC32	viability	TCACCCCAATGTAGCGCCGCTGG	HTRA2	ENSG00000115317	-0.0635169183966548	[535]	[383,434,648,489]	-1	hSpCas9	negative selection	9492839
74530642	74530665	2	-	27260156	TC32	viability	AATCCTGAGCCGTTCGAGATAGG	HTRA2	ENSG00000115317	-0.06007577245200191	[469]	[343,307,602,504]	-1	hSpCas9	negative selection	9492840
74531014	74531037	2	-	27260156	TC32	viability	CTGAGCAGAGCTAACAATGCCGG	HTRA2	ENSG00000115317	-0.44509594789486084	[597]	[369,185,617,592]	-7	hSpCas9	negative selection	9492841
74530045	74530068	2	-	27869803	HPAFII	viability after 27 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	-0.0024809895037550267	[290]	[221,94,NaN]	0	hSpCas9	negative selection	9575834
74530621	74530644	2	-	27869803	HPAFII	viability after 27 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	1.4423722008049842	[59]	[76,92,NaN]	9	hSpCas9	negative selection	9575835
74530940	74530963	2	+	27869803	HPAFII	viability after 27 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	0.13888369705034553	[652]	[491,282,NaN]	1	hSpCas9	negative selection	9575836
74531359	74531382	2	-	27869803	HPAFII	viability after 27 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.15057714589517995	[340]	[300,113,NaN]	1	hSpCas9	negative selection	9575837
74531646	74531669	2	-	27869803	HPAFII	viability after 27 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	0.320078369709639	[345]	[411,72,NaN]	2	hSpCas9	negative selection	9575838
74531865	74531888	2	+	27869803	HPAFII	viability after 27 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	0.4851533519888007	[368]	[342,211,NaN]	4	hSpCas9	negative selection	9575839
74530045	74530068	2	-	27869803	HPAFII	viability after 15 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.4996871426945442	[290]	[731,261,NaN]	6	hSpCas9	negative selection	9658283
74530621	74530644	2	-	27869803	HPAFII	viability after 15 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.7632702514772536	[59]	[114,105,NaN]	8	hSpCas9	negative selection	9658284
74530940	74530963	2	+	27869803	HPAFII	viability after 15 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.0547430775780966	[652]	[1036,450,NaN]	0	hSpCas9	negative selection	9658285
74531359	74531382	2	-	27869803	HPAFII	viability after 15 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.3332417293895393	[340]	[568,394,NaN]	4	hSpCas9	negative selection	9658286
74531646	74531669	2	-	27869803	HPAFII	viability after 15 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-0.15467692150747897	[345]	[695,108,NaN]	-2	hSpCas9	negative selection	9658287
74531865	74531888	2	+	27869803	HPAFII	viability after 15 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	-0.17538354455541189	[368]	[492,262,NaN]	-2	hSpCas9	negative selection	9658288
74530045	74530068	2	-	27869803	ASPC1	viability after 36 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	1.63155982700765	[903]	[2676,326,291]	9	hSpCas9	negative selection	9740732
74530621	74530644	2	-	27869803	ASPC1	viability after 36 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	0.1729870957163404	[268]	[143,91,88]	1	hSpCas9	negative selection	9740733
74530940	74530963	2	+	27869803	ASPC1	viability after 36 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	0.06903951531863783	[1891]	[313,1220,531]	0	hSpCas9	negative selection	9740734
74531359	74531382	2	-	27869803	ASPC1	viability after 36 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.7269746681869056	[847]	[883,274,378]	7	hSpCas9	negative selection	9740735
74531646	74531669	2	-	27869803	ASPC1	viability after 36 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	0.4108869329168882	[855]	[816,130,309]	4	hSpCas9	negative selection	9740736
74531865	74531888	2	+	27869803	ASPC1	viability after 36 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	0.1497996865405391	[912]	[462,165,421]	1	hSpCas9	negative selection	9740737
74530045	74530068	2	-	27869803	PATU8988S	viability after 35 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.20110084885474294	[749]	[453,239,NaN]	2	hSpCas9	negative selection	9823181
74530621	74530644	2	-	27869803	PATU8988S	viability after 35 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	-1.8213261903810691	[236]	[30,22,NaN]	-8	hSpCas9	negative selection	9823182
74530940	74530963	2	+	27869803	PATU8988S	viability after 35 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-1.3597850623071788	[1305]	[181,227,NaN]	-8	hSpCas9	negative selection	9823183
74531359	74531382	2	-	27869803	PATU8988S	viability after 35 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	-1.3212635985308634	[588]	[64,124,NaN]	-8	hSpCas9	negative selection	9823184
74531646	74531669	2	-	27869803	PATU8988S	viability after 35 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-1.8828409455934438	[594]	[54,74,NaN]	-9	hSpCas9	negative selection	9823185
74531865	74531888	2	+	27869803	PATU8988S	viability after 35 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	-0.8126112235277572	[749]	[162,180,NaN]	-7	hSpCas9	negative selection	9823186
74530045	74530068	2	-	27869803	PATU8988S	viability after 31 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	0.1357438033411224	[749]	[339,313,NaN]	1	hSpCas9	negative selection	9905630
74530621	74530644	2	-	27869803	PATU8988S	viability after 31 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	-1.8977622576303395	[236]	[27,21,NaN]	-9	hSpCas9	negative selection	9905631
74530940	74530963	2	+	27869803	PATU8988S	viability after 31 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-1.1422448588165415	[1305]	[99,408,NaN]	-8	hSpCas9	negative selection	9905632
74531359	74531382	2	-	27869803	PATU8988S	viability after 31 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	-1.3465227054258315	[588]	[72,116,NaN]	-8	hSpCas9	negative selection	9905633
74531646	74531669	2	-	27869803	PATU8988S	viability after 31 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	-1.2309016052260957	[594]	[108,90,NaN]	-8	hSpCas9	negative selection	9905634
74531865	74531888	2	+	27869803	PATU8988S	viability after 31 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	-0.7678809396959779	[749]	[128,234,NaN]	-7	hSpCas9	negative selection	9905635
74530045	74530068	2	-	27869803	HPAFII	viability after 35 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	-0.2223423662596334	[290]	[209,31,NaN]	-1	hSpCas9	negative selection	9988079
74530621	74530644	2	-	27869803	HPAFII	viability after 35 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	1.8870263560250686	[59]	[101,123,NaN]	9	hSpCas9	negative selection	9988080
74530940	74530963	2	+	27869803	HPAFII	viability after 35 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	0.05126770805463887	[652]	[358,323,NaN]	0	hSpCas9	negative selection	9988081
74531359	74531382	2	-	27869803	HPAFII	viability after 35 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.9713968388091672	[340]	[361,311,NaN]	6	hSpCas9	negative selection	9988082
74531646	74531669	2	-	27869803	HPAFII	viability after 35 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	0.7347634924833187	[345]	[449,112,NaN]	5	hSpCas9	negative selection	9988083
74531865	74531888	2	+	27869803	HPAFII	viability after 35 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	0.358005217333229	[368]	[134,356,NaN]	2	hSpCas9	negative selection	9988084
74530045	74530068	2	-	27869803	HPAFII	viability after 31 days	CCAAAGCCCGCCATGCCCGAAGG	HTRA2	ENSG00000115317	-0.7380566836588182	[290]	[162,26,NaN]	-5	hSpCas9	negative selection	10070528
74530621	74530644	2	-	27869803	HPAFII	viability after 31 days	GGGACCTCGCGGCCCAAGAAAGG	HTRA2	ENSG00000115317	1.4824939069694703	[59]	[84,103,NaN]	9	hSpCas9	negative selection	10070529
74530940	74530963	2	+	27869803	HPAFII	viability after 31 days	CTCAGCTGATGTCCGGCAAGGGG	HTRA2	ENSG00000115317	-0.26355171126896626	[652]	[333,273,NaN]	-2	hSpCas9	negative selection	10070530
74531359	74531382	2	-	27869803	HPAFII	viability after 31 days	TCTCACTCACCAGGTTAACCAGG	HTRA2	ENSG00000115317	0.585762847958917	[340]	[280,293,NaN]	4	hSpCas9	negative selection	10070531
74531646	74531669	2	-	27869803	HPAFII	viability after 31 days	ACGATCAGAAGGGATGGCAAAGG	HTRA2	ENSG00000115317	0.7254292578515976	[345]	[500,124,NaN]	5	hSpCas9	negative selection	10070532
74531865	74531888	2	+	27869803	HPAFII	viability after 31 days	CCGGAATCAGTGGGTCCCAGCGG	HTRA2	ENSG00000115317	0.5323751992171342	[368]	[176,432,NaN]	4	hSpCas9	negative selection	10070533
74530468	74530491	2	+	28162770	P31FUJ	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-2.398139936361039	[156]	[34]	-8	hSpCas9	negative selection	10172104
74530660	74530683	2	+	28162770	P31FUJ	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	-5.348279421834315	[103]	[2]	-9	hSpCas9	negative selection	10172105
74530650	74530673	2	+	28162770	P31FUJ	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-1.4865587966601614	[61]	[25]	-7	hSpCas9	negative selection	10172106
74531608	74531631	2	+	28162770	P31FUJ	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-1.6278218101162651	[333]	[126]	-7	hSpCas9	negative selection	10172107
74530003	74530026	2	+	28162770	P31FUJ	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-1.5476755417677903	[101]	[40]	-7	hSpCas9	negative selection	10172108
74530108	74530131	2	-	28162770	P31FUJ	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	0.7705181538772327	[216]	[434]	8	hSpCas9	negative selection	10172109
74530168	74530191	2	-	28162770	P31FUJ	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	-1.3791916913959017	[227]	[102]	-7	hSpCas9	negative selection	10172110
74530355	74530378	2	+	28162770	P31FUJ	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-0.6374680196207839	[461]	[348]	-5	hSpCas9	negative selection	10172111
74530425	74530448	2	-	28162770	P31FUJ	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-1.038154773560835	[359]	[205]	-6	hSpCas9	negative selection	10172112
74530620	74530643	2	-	28162770	P31FUJ	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-1.8318398903472572	[308]	[101]	-8	hSpCas9	negative selection	10172113
74530468	74530491	2	+	28162770	TF1	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10341470
74530660	74530683	2	+	28162770	TF1	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10341471
74530650	74530673	2	+	28162770	TF1	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10341472
74531608	74531631	2	+	28162770	TF1	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	NaN	[NaN]	[270]	1	hSpCas9	negative selection	10341473
74530003	74530026	2	+	28162770	TF1	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10341474
74530108	74530131	2	-	28162770	TF1	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	NaN	[NaN]	[194]	1	hSpCas9	negative selection	10341475
74530168	74530191	2	-	28162770	TF1	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	NaN	[NaN]	[163]	1	hSpCas9	negative selection	10341476
74530355	74530378	2	+	28162770	TF1	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	NaN	[NaN]	[394]	1	hSpCas9	negative selection	10341477
74530425	74530448	2	-	28162770	TF1	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	NaN	[NaN]	[175]	1	hSpCas9	negative selection	10341478
74530620	74530643	2	-	28162770	TF1	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	NaN	[NaN]	[311]	1	hSpCas9	negative selection	10341479
74530468	74530491	2	+	28162770	SKM1	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-2.603361411546665	[54]	[15]	-9	hSpCas9	negative selection	10510836
74530660	74530683	2	+	28162770	SKM1	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	0.7114305020590685	[18]	[54]	6	hSpCas9	negative selection	10510837
74530650	74530673	2	+	28162770	SKM1	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-2.4069641987431614	[23]	[7]	-8	hSpCas9	negative selection	10510838
74531608	74531631	2	+	28162770	SKM1	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-1.1030218493291617	[112]	[92]	-7	hSpCas9	negative selection	10510839
74530003	74530026	2	+	28162770	SKM1	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-0.734538856771666	[31]	[33]	-5	hSpCas9	negative selection	10510840
74530108	74530131	2	-	28162770	SKM1	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	1.0207585601667974	[45]	[164]	8	hSpCas9	negative selection	10510841
74530168	74530191	2	-	28162770	SKM1	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	0.22106702386988042	[32]	[67]	2	hSpCas9	negative selection	10510842
74530355	74530378	2	+	28162770	SKM1	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-0.12473622767605708	[139]	[226]	-1	hSpCas9	negative selection	10510843
74530425	74530448	2	-	28162770	SKM1	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-0.56566194476222	[71]	[85]	-4	hSpCas9	negative selection	10510844
74530620	74530643	2	-	28162770	SKM1	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-0.5224414161630978	[64]	[79]	-4	hSpCas9	negative selection	10510845
74530468	74530491	2	+	28162770	SKM1	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-2.603361411546665	[54]	[15]	-9	hSpCas9	negative selection	10680202
74530660	74530683	2	+	28162770	SKM1	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	0.7114305020590685	[18]	[54]	6	hSpCas9	negative selection	10680203
74530650	74530673	2	+	28162770	SKM1	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-2.4069641987431614	[23]	[7]	-8	hSpCas9	negative selection	10680204
74531608	74531631	2	+	28162770	SKM1	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-1.1030218493291617	[112]	[92]	-7	hSpCas9	negative selection	10680205
74530003	74530026	2	+	28162770	SKM1	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-0.734538856771666	[31]	[33]	-5	hSpCas9	negative selection	10680206
74530108	74530131	2	-	28162770	SKM1	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	1.0207585601667974	[45]	[164]	8	hSpCas9	negative selection	10680207
74530168	74530191	2	-	28162770	SKM1	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	0.22106702386988042	[32]	[67]	2	hSpCas9	negative selection	10680208
74530355	74530378	2	+	28162770	SKM1	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-0.12473622767605708	[139]	[226]	-1	hSpCas9	negative selection	10680209
74530425	74530448	2	-	28162770	SKM1	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-0.56566194476222	[71]	[85]	-4	hSpCas9	negative selection	10680210
74530620	74530643	2	-	28162770	SKM1	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-0.5224414161630978	[64]	[79]	-4	hSpCas9	negative selection	10680211
74530468	74530491	2	+	28162770	PL21	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-2.5783026156530453	[246]	[17]	-9	hSpCas9	negative selection	10849568
74530660	74530683	2	+	28162770	PL21	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	-2.595719668730455	[124]	[8]	-9	hSpCas9	negative selection	10849569
74530650	74530673	2	+	28162770	PL21	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-4.8442545048691334	[65]	[0]	-9	hSpCas9	negative selection	10849570
74531608	74531631	2	+	28162770	PL21	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-0.5682690273277673	[401]	[117]	-4	hSpCas9	negative selection	10849571
74530003	74530026	2	+	28162770	PL21	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-0.5302533257533999	[72]	[21]	-4	hSpCas9	negative selection	10849572
74530108	74530131	2	-	28162770	PL21	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	-0.3098608285506139	[224]	[78]	-2	hSpCas9	negative selection	10849573
74530168	74530191	2	-	28162770	PL21	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	0.8539639733552804	[149]	[117]	7	hSpCas9	negative selection	10849574
74530355	74530378	2	+	28162770	PL21	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-1.0352384484416084	[371]	[78]	-6	hSpCas9	negative selection	10849575
74530425	74530448	2	-	28162770	PL21	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-2.3119723208241543	[250]	[21]	-8	hSpCas9	negative selection	10849576
74530620	74530643	2	-	28162770	PL21	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-0.4580718682624746	[201]	[63]	-3	hSpCas9	negative selection	10849577
74530468	74530491	2	+	28162770	P31FUJ	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-2.398139936361039	[156]	[34]	-8	hSpCas9	negative selection	11018934
74530660	74530683	2	+	28162770	P31FUJ	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	-5.348279421834315	[103]	[2]	-9	hSpCas9	negative selection	11018935
74530650	74530673	2	+	28162770	P31FUJ	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-1.4865587966601614	[61]	[25]	-7	hSpCas9	negative selection	11018936
74531608	74531631	2	+	28162770	P31FUJ	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-1.6278218101162651	[333]	[126]	-7	hSpCas9	negative selection	11018937
74530003	74530026	2	+	28162770	P31FUJ	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-1.5476755417677903	[101]	[40]	-7	hSpCas9	negative selection	11018938
74530108	74530131	2	-	28162770	P31FUJ	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	0.7705181538772327	[216]	[434]	8	hSpCas9	negative selection	11018939
74530168	74530191	2	-	28162770	P31FUJ	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	-1.3791916913959017	[227]	[102]	-7	hSpCas9	negative selection	11018940
74530355	74530378	2	+	28162770	P31FUJ	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-0.6374680196207839	[461]	[348]	-5	hSpCas9	negative selection	11018941
74530425	74530448	2	-	28162770	P31FUJ	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-1.038154773560835	[359]	[205]	-6	hSpCas9	negative selection	11018942
74530620	74530643	2	-	28162770	P31FUJ	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-1.8318398903472572	[308]	[101]	-8	hSpCas9	negative selection	11018943
74530468	74530491	2	+	28162770	OCIAML5	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-0.94639395341215	[78]	[73]	-5	hSpCas9	negative selection	11188300
74530660	74530683	2	+	28162770	OCIAML5	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	0.28811108718426326	[48]	[107]	2	hSpCas9	negative selection	11188301
74530650	74530673	2	+	28162770	OCIAML5	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-4.137468789726245	[38]	[3]	-9	hSpCas9	negative selection	11188302
74531608	74531631	2	+	28162770	OCIAML5	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-0.7623364102079847	[186]	[198]	-5	hSpCas9	negative selection	11188303
74530003	74530026	2	+	28162770	OCIAML5	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-0.852066570863997	[40]	[40]	-5	hSpCas9	negative selection	11188304
74530108	74530131	2	-	28162770	OCIAML5	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	0.5046269421840419	[122]	[314]	4	hSpCas9	negative selection	11188305
74530168	74530191	2	-	28162770	OCIAML5	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	-0.625558041055317	[99]	[116]	-4	hSpCas9	negative selection	11188306
74530355	74530378	2	+	28162770	OCIAML5	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-0.6644395676882258	[251]	[286]	-4	hSpCas9	negative selection	11188307
74530425	74530448	2	-	28162770	OCIAML5	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-0.6037196083577421	[180]	[214]	-4	hSpCas9	negative selection	11188308
74530620	74530643	2	-	28162770	OCIAML5	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-1.0447116488063928	[175]	[153]	-6	hSpCas9	negative selection	11188309
74530468	74530491	2	+	28162770	EOL1	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-7.626199013812709	[374]	[0]	-9	hSpCas9	negative selection	11357666
74530660	74530683	2	+	28162770	EOL1	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	-3.0978200414579202	[129]	[7]	-9	hSpCas9	negative selection	11357667
74530650	74530673	2	+	28162770	EOL1	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-5.614611039537497	[92]	[0]	-9	hSpCas9	negative selection	11357668
74531608	74531631	2	+	28162770	EOL1	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-1.8594860762524505	[674]	[97]	-8	hSpCas9	negative selection	11357669
74530003	74530026	2	+	28162770	EOL1	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-5.518395724278194	[173]	[1]	-9	hSpCas9	negative selection	11357670
74530108	74530131	2	-	28162770	EOL1	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	0.49779685172790045	[370]	[275]	4	hSpCas9	negative selection	11357671
74530168	74530191	2	-	28162770	EOL1	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	-1.0270118733717122	[204]	[52]	-6	hSpCas9	negative selection	11357672
74530355	74530378	2	+	28162770	EOL1	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-2.6469942133882998	[427]	[35]	-9	hSpCas9	negative selection	11357673
74530425	74530448	2	-	28162770	EOL1	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-1.1534547404307385	[379]	[89]	-6	hSpCas9	negative selection	11357674
74530620	74530643	2	-	28162770	EOL1	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-1.2586740524852356	[326]	[71]	-7	hSpCas9	negative selection	11357675
74530468	74530491	2	+	28162770	MOLM13	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-4.986067107026567	[262]	[5]	-9	hSpCas9	negative selection	11527032
74530660	74530683	2	+	28162770	MOLM13	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	-4.002430553235454	[132]	[5]	-9	hSpCas9	negative selection	11527033
74530650	74530673	2	+	28162770	MOLM13	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-5.7020356198977336	[71]	[0]	-9	hSpCas9	negative selection	11527034
74531608	74531631	2	+	28162770	MOLM13	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-1.0853105567917896	[583]	[198]	-5	hSpCas9	negative selection	11527035
74530003	74530026	2	+	28162770	MOLM13	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	0.7898174764319414	[111]	[139]	6	hSpCas9	negative selection	11527036
74530108	74530131	2	-	28162770	MOLM13	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	-0.0874479500672993	[240]	[163]	0	hSpCas9	negative selection	11527037
74530168	74530191	2	-	28162770	MOLM13	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	-3.012103559575035	[211]	[18]	-8	hSpCas9	negative selection	11527038
74530355	74530378	2	+	28162770	MOLM13	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-2.060953032844677	[478]	[82]	-7	hSpCas9	negative selection	11527039
74530425	74530448	2	-	28162770	MOLM13	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-1.1499877416493123	[398]	[129]	-6	hSpCas9	negative selection	11527040
74530620	74530643	2	-	28162770	MOLM13	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-7.671661970854215	[281]	[0]	-9	hSpCas9	negative selection	11527041
74530468	74530491	2	+	28162770	HEL	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-1.85476082747046	[287]	[50]	-7	hSpCas9	negative selection	11696398
74530660	74530683	2	+	28162770	HEL	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	-0.6129160434678393	[116]	[48]	-4	hSpCas9	negative selection	11696399
74530650	74530673	2	+	28162770	HEL	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-2.710898122614344	[91]	[8]	-8	hSpCas9	negative selection	11696400
74531608	74531631	2	+	28162770	HEL	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-1.1499940556924022	[588]	[169]	-6	hSpCas9	negative selection	11696401
74530003	74530026	2	+	28162770	HEL	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-0.3040191467226634	[132]	[68]	-2	hSpCas9	negative selection	11696402
74530108	74530131	2	-	28162770	HEL	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	1.092349479826627	[267]	[365]	8	hSpCas9	negative selection	11696403
74530168	74530191	2	-	28162770	HEL	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	-0.7357727912533728	[233]	[89]	-5	hSpCas9	negative selection	11696404
74530355	74530378	2	+	28162770	HEL	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-3.0671819391516206	[457]	[34]	-8	hSpCas9	negative selection	11696405
74530425	74530448	2	-	28162770	HEL	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-0.26920499133444714	[285]	[151]	-2	hSpCas9	negative selection	11696406
74530620	74530643	2	-	28162770	HEL	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-1.6682597027287462	[262]	[52]	-7	hSpCas9	negative selection	11696407
74530468	74530491	2	+	28162770	MV411	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-4.804224569039717	[198]	[5]	-9	hSpCas9	negative selection	11865764
74530660	74530683	2	+	28162770	MV411	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	-4.4249877911887205	[101]	[3]	-9	hSpCas9	negative selection	11865765
74530650	74530673	2	+	28162770	MV411	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-5.922487450659537	[71]	[0]	-9	hSpCas9	negative selection	11865766
74531608	74531631	2	+	28162770	MV411	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-0.9494197784465351	[391]	[170]	-6	hSpCas9	negative selection	11865767
74530003	74530026	2	+	28162770	MV411	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-2.174026217655501	[74]	[13]	-8	hSpCas9	negative selection	11865768
74530108	74530131	2	-	28162770	MV411	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	0.9024475490321879	[133]	[210]	7	hSpCas9	negative selection	11865769
74530168	74530191	2	-	28162770	MV411	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	-0.184513331432415	[142]	[105]	-1	hSpCas9	negative selection	11865770
74530355	74530378	2	+	28162770	MV411	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-1.2247570197764313	[368]	[132]	-7	hSpCas9	negative selection	11865771
74530425	74530448	2	-	28162770	MV411	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-1.1378526051020166	[255]	[97]	-6	hSpCas9	negative selection	11865772
74530620	74530643	2	-	28162770	MV411	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-1.3714722818617187	[214]	[69]	-7	hSpCas9	negative selection	11865773
74530468	74530491	2	+	28162770	MONOMAC1	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	0.15619536774581833	[154]	[197]	1	hSpCas9	negative selection	12035130
74530660	74530683	2	+	28162770	MONOMAC1	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	-0.8100137239503064	[77]	[50]	-6	hSpCas9	negative selection	12035131
74530650	74530673	2	+	28162770	MONOMAC1	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	0.2927684206212624	[46]	[65]	3	hSpCas9	negative selection	12035132
74531608	74531631	2	+	28162770	MONOMAC1	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-0.15970069578658097	[266]	[273]	-1	hSpCas9	negative selection	12035133
74530003	74530026	2	+	28162770	MONOMAC1	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-0.006705634955404216	[77]	[88]	0	hSpCas9	negative selection	12035134
74530108	74530131	2	-	28162770	MONOMAC1	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	0.710844950952015	[96]	[181]	6	hSpCas9	negative selection	12035135
74530168	74530191	2	-	28162770	MONOMAC1	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	-0.032917467298447134	[82]	[92]	0	hSpCas9	negative selection	12035136
74530355	74530378	2	+	28162770	MONOMAC1	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-0.30211889311711115	[241]	[224]	-3	hSpCas9	negative selection	12035137
74530425	74530448	2	-	28162770	MONOMAC1	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	1.5360242926507364	[147]	[491]	9	hSpCas9	negative selection	12035138
74530620	74530643	2	-	28162770	MONOMAC1	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	0.6072386820660785	[133]	[233]	6	hSpCas9	negative selection	12035139
74530468	74530491	2	+	28162770	OCIAML2	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-2.4035156293836244	[41]	[43]	-8	hSpCas9	negative selection	12204496
74530660	74530683	2	+	28162770	OCIAML2	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	-2.470629825242161	[14]	[14]	-8	hSpCas9	negative selection	12204497
74530650	74530673	2	+	28162770	OCIAML2	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-2.1811232080471763	[8]	[10]	-8	hSpCas9	negative selection	12204498
74531608	74531631	2	+	28162770	OCIAML2	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-1.9763656348127423	[92]	[130]	-8	hSpCas9	negative selection	12204499
74530003	74530026	2	+	28162770	OCIAML2	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-0.9852029980719195	[19]	[55]	-6	hSpCas9	negative selection	12204500
74530108	74530131	2	-	28162770	OCIAML2	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	0.7772976882014241	[25]	[246]	7	hSpCas9	negative selection	12204501
74530168	74530191	2	-	28162770	OCIAML2	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	-0.9329730392993615	[30]	[89]	-6	hSpCas9	negative selection	12204502
74530355	74530378	2	+	28162770	OCIAML2	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-1.153439649361462	[60]	[151]	-6	hSpCas9	negative selection	12204503
74530425	74530448	2	-	28162770	OCIAML2	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-1.5961607073260202	[59]	[109]	-7	hSpCas9	negative selection	12204504
74530620	74530643	2	-	28162770	OCIAML2	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-3.5775450291586735	[55]	[25]	-9	hSpCas9	negative selection	12204505
74530468	74530491	2	+	28162770	OCIAML3	viability	GGAGAAGACAGCACCTGCCGTGG	HTRA2	ENSG00000115317	-0.6287730584848401	[20]	[40]	-5	hSpCas9	negative selection	12373862
74530660	74530683	2	+	28162770	OCIAML3	viability	GGATTCGTGGTGGCTGCCGATGG	HTRA2	ENSG00000115317	-1.7460107337692132	[19]	[17]	-8	hSpCas9	negative selection	12373863
74530650	74530673	2	+	28162770	OCIAML3	viability	GAACGGCTCAGGATTCGTGGTGG	HTRA2	ENSG00000115317	-1.4785304229042269	[11]	[12]	-7	hSpCas9	negative selection	12373864
74531608	74531631	2	+	28162770	OCIAML3	viability	GATTGGAGTGAACACCATGAAGG	HTRA2	ENSG00000115317	-0.5657185958927394	[100]	[205]	-4	hSpCas9	negative selection	12373865
74530003	74530026	2	+	28162770	OCIAML3	viability	GCTGATGGCTGCGCCGAGGGCGG	HTRA2	ENSG00000115317	-0.9501514505494384	[31]	[49]	-6	hSpCas9	negative selection	12373866
74530108	74530131	2	-	28162770	OCIAML3	viability	CTGACGTCAGCAGGGCCCGGAGG	HTRA2	ENSG00000115317	-0.1859229016870862	[51]	[137]	-1	hSpCas9	negative selection	12373867
74530168	74530191	2	-	28162770	OCIAML3	viability	ACAACCGGGCCCAGAGACTGGGG	HTRA2	ENSG00000115317	-1.5629807447035389	[45]	[46]	-8	hSpCas9	negative selection	12373868
74530355	74530378	2	+	28162770	OCIAML3	viability	GTGCTGTTGTTGTTGTGGGGCGG	HTRA2	ENSG00000115317	-0.38421525576734894	[114]	[265]	-3	hSpCas9	negative selection	12373869
74530425	74530448	2	-	28162770	OCIAML3	viability	GTACTGACTCCGGGGAGAAGCGG	HTRA2	ENSG00000115317	-0.486479176019718	[83]	[180]	-4	hSpCas9	negative selection	12373870
74530620	74530643	2	-	28162770	OCIAML3	viability	GGACCTCGCGGCCCAAGAAAGGG	HTRA2	ENSG00000115317	-2.4289483940536667	[65]	[36]	-9	hSpCas9	negative selection	12373871