Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6453
• Symbol: ITSN1
• Description: intersectin 1

DataSource: http://genomecrispr.dkfz.de/#!/results/ITSN1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
33718827	33718850	21	-	26472758	Jiyoye	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	-0.40840004735669916	[219]	[124]	-3	hSpCas9	negative selection	80041
33735154	33735177	21	-	26472758	Jiyoye	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	-0.8389852057635242	[305]	[128]	-5	hSpCas9	negative selection	80042
33750166	33750189	21	-	26472758	Jiyoye	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	0.07576623360762569	[228]	[181]	0	hSpCas9	negative selection	80043
33750298	33750321	21	-	26472758	Jiyoye	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.4931486046157263	[113]	[120]	4	hSpCas9	negative selection	80044
33765966	33765989	21	-	26472758	Jiyoye	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-3.023874435761601	[150]	[13]	-9	hSpCas9	negative selection	80045
33772248	33772271	21	+	26472758	Jiyoye	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	0.7410761180593118	[95]	[120]	5	hSpCas9	negative selection	80046
33772272	33772295	21	+	26472758	Jiyoye	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	-0.4715183222719932	[56]	[30]	-3	hSpCas9	negative selection	80047
33811153	33811176	21	-	26472758	Jiyoye	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	0.38879685219101867	[78]	[77]	3	hSpCas9	negative selection	80048
33813993	33814016	21	+	26472758	Jiyoye	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	0.2834400130836287	[72]	[66]	2	hSpCas9	negative selection	80049
33814047	33814070	21	-	26472758	Jiyoye	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	-0.3654141223910541	[40]	[23]	-3	hSpCas9	negative selection	80050
33718827	33718850	21	-	26472758	KBM7	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	0.1952317847468477	[648,362]	[400,144]	2	hSpCas9	negative selection	271159
33735154	33735177	21	-	26472758	KBM7	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	0.4511632421104401	[933,793]	[430,662]	5	hSpCas9	negative selection	271160
33750166	33750189	21	-	26472758	KBM7	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	0.14355847408415234	[398,453]	[307,148]	1	hSpCas9	negative selection	271161
33750298	33750321	21	-	26472758	KBM7	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.3577005333009707	[544,581]	[298,380]	4	hSpCas9	negative selection	271162
33765966	33765989	21	-	26472758	KBM7	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-3.029268390297122	[641,597]	[30,39]	-9	hSpCas9	negative selection	271163
33772248	33772271	21	+	26472758	KBM7	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	0.7643884355751951	[410,307]	[334,238]	8	hSpCas9	negative selection	271164
33772272	33772295	21	+	26472758	KBM7	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	0.25711604208228633	[320,288]	[193,150]	2	hSpCas9	negative selection	271165
33811153	33811176	21	-	26472758	KBM7	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	0.49954192618124144	[215,276]	[152,178]	5	hSpCas9	negative selection	271166
33813993	33814016	21	+	26472758	KBM7	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	0.567289534780894	[289,293]	[174,230]	6	hSpCas9	negative selection	271167
33814047	33814070	21	-	26472758	KBM7	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	0.919014387463631	[152,147]	[129,137]	8	hSpCas9	negative selection	271168
33718827	33718850	21	-	26472758	Raji	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	-0.27112808788013026	[259]	[49]	-2	hSpCas9	negative selection	462277
33735154	33735177	21	-	26472758	Raji	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	-0.17015044015530945	[479]	[98]	-1	hSpCas9	negative selection	462278
33750166	33750189	21	-	26472758	Raji	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	-0.26018722506947534	[288]	[55]	-2	hSpCas9	negative selection	462279
33750298	33750321	21	-	26472758	Raji	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.5057422935058129	[260]	[85]	5	hSpCas9	negative selection	462280
33765966	33765989	21	-	26472758	Raji	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-1.7995070602349192	[269]	[17]	-8	hSpCas9	negative selection	462281
33772248	33772271	21	+	26472758	Raji	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	0.9340519324880376	[105]	[46]	8	hSpCas9	negative selection	462282
33772272	33772295	21	+	26472758	Raji	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	-0.8519744801290547	[139]	[17]	-6	hSpCas9	negative selection	462283
33811153	33811176	21	-	26472758	Raji	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	0.3048295995798166	[149]	[42]	3	hSpCas9	negative selection	462284
33813993	33814016	21	+	26472758	Raji	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	-0.6004357131330904	[195]	[29]	-5	hSpCas9	negative selection	462285
33814047	33814070	21	-	26472758	Raji	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	0.48963109953477363	[177]	[57]	4	hSpCas9	negative selection	462286
33718827	33718850	21	-	26472758	K562	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	-0.09050020574067619	[501]	[397]	0	hSpCas9	negative selection	653395
33735154	33735177	21	-	26472758	K562	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	-0.22090052605522004	[797]	[577]	-1	hSpCas9	negative selection	653396
33750166	33750189	21	-	26472758	K562	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	-0.3651532403987108	[472]	[309]	-2	hSpCas9	negative selection	653397
33750298	33750321	21	-	26472758	K562	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.23014863069980807	[507]	[502]	1	hSpCas9	negative selection	653398
33765966	33765989	21	-	26472758	K562	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-2.325896997090308	[391]	[65]	-8	hSpCas9	negative selection	653399
33772248	33772271	21	+	26472758	K562	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	-0.24184226838560008	[345]	[246]	-2	hSpCas9	negative selection	653400
33772272	33772295	21	+	26472758	K562	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	-0.0656839318241258	[242]	[195]	0	hSpCas9	negative selection	653401
33811153	33811176	21	-	26472758	K562	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	-0.17289971286363526	[210]	[157]	-1	hSpCas9	negative selection	653402
33813993	33814016	21	+	26472758	K562	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	0.9016571293619189	[278]	[439]	7	hSpCas9	negative selection	653403
33814047	33814070	21	-	26472758	K562	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	-0.5491303948661268	[155]	[89]	-3	hSpCas9	negative selection	653404
33735155	33735178	21	-	26627737	DLD1	viability	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.5350645367045153	[850]	[411,385,361]	5	hSpCas9	negative selection	816069
33750283	33750306	21	-	26627737	DLD1	viability	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	0.27855615147423646	[314]	[71,229,68]	3	hSpCas9	negative selection	816070
33755304	33755327	21	-	26627737	DLD1	viability	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-1.1866164208638343	[137]	[11,30,14]	-8	hSpCas9	negative selection	816071
33761954	33761977	21	+	26627737	DLD1	viability	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	1.0769148779105113	[194]	[94,219,81]	8	hSpCas9	negative selection	816072
33772269	33772292	21	+	26627737	DLD1	viability	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.19872399523731843	[772]	[193,306,144]	-2	hSpCas9	negative selection	816073
33775011	33775034	21	+	26627737	DLD1	viability	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	1.3059575209838772	[79]	[30,47,99]	9	hSpCas9	negative selection	816074
33735155	33735178	21	-	26627737	GBM cells	viability after 5 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	-0.0022683888963990206	[535]	[312,260]	0	hSpCas9	negative selection	898384
33750283	33750306	21	-	26627737	GBM cells	viability after 5 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	0.03218040574914979	[216]	[88,148]	0	hSpCas9	negative selection	898385
33755304	33755327	21	-	26627737	GBM cells	viability after 5 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-0.3337468819045897	[93]	[41,37]	-5	hSpCas9	negative selection	898386
33761954	33761977	21	+	26627737	GBM cells	viability after 5 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.22408034383959258	[177]	[98,123]	3	hSpCas9	negative selection	898387
33772269	33772292	21	+	26627737	GBM cells	viability after 5 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.017213567859294565	[283]	[151,148]	0	hSpCas9	negative selection	898388
33775011	33775034	21	+	26627737	GBM cells	viability after 5 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.6358794690518916	[65]	[52,56]	8	hSpCas9	negative selection	898389
33735155	33735178	21	-	26627737	GBM cells	viability after 13 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.16337475808958435	[535]	[403,261]	2	hSpCas9	negative selection	980699
33750283	33750306	21	-	26627737	GBM cells	viability after 13 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-0.06519552570201725	[216]	[154,77]	-1	hSpCas9	negative selection	980700
33755304	33755327	21	-	26627737	GBM cells	viability after 13 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-0.6471832874642129	[93]	[63,6]	-6	hSpCas9	negative selection	980701
33761954	33761977	21	+	26627737	GBM cells	viability after 13 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.24751775155411235	[177]	[112,115]	3	hSpCas9	negative selection	980702
33772269	33772292	21	+	26627737	GBM cells	viability after 13 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	0.42112055133068726	[283]	[234,182]	5	hSpCas9	negative selection	980703
33775011	33775034	21	+	26627737	GBM cells	viability after 13 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.8323952043235261	[65]	[76,52]	8	hSpCas9	negative selection	980704
33735155	33735178	21	-	26627737	GBM cells	viability after 21 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	-0.18035609369473926	[535]	[280,234]	-2	hSpCas9	negative selection	1063014
33750283	33750306	21	-	26627737	GBM cells	viability after 21 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	0.7809350481077202	[216]	[200,203]	7	hSpCas9	negative selection	1063015
33755304	33755327	21	-	26627737	GBM cells	viability after 21 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-1.0107579170795162	[93]	[28,21]	-7	hSpCas9	negative selection	1063016
33761954	33761977	21	+	26627737	GBM cells	viability after 21 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.3168569923707836	[177]	[144,97]	3	hSpCas9	negative selection	1063017
33772269	33772292	21	+	26627737	GBM cells	viability after 21 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	0.7346754290614417	[283]	[250,261]	7	hSpCas9	negative selection	1063018
33775011	33775034	21	+	26627737	GBM cells	viability after 21 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	1.0159693560193943	[65]	[83,61]	8	hSpCas9	negative selection	1063019
33735155	33735178	21	-	26627737	RPE1	viability after 9 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.22129653189726772	[2306]	[741,970]	1	hSpCas9	negative selection	1145329
33750283	33750306	21	-	26627737	RPE1	viability after 9 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	0.38470753979840044	[580]	[257,210]	2	hSpCas9	negative selection	1145330
33755304	33755327	21	-	26627737	RPE1	viability after 9 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-0.4708936379745908	[607]	[149,120]	-3	hSpCas9	negative selection	1145331
33761954	33761977	21	+	26627737	RPE1	viability after 9 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	-0.8153453341676942	[767]	[109,170]	-5	hSpCas9	negative selection	1145332
33772269	33772292	21	+	26627737	RPE1	viability after 9 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.7819133589039428	[1920]	[268,453]	-5	hSpCas9	negative selection	1145333
33775011	33775034	21	+	26627737	RPE1	viability after 9 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	-0.3453564053871483	[364]	[92,85]	-2	hSpCas9	negative selection	1145334
33735155	33735178	21	-	26627737	RPE1	viability after 12 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.14625370964347684	[2306]	[513,867]	1	hSpCas9	negative selection	1227644
33750283	33750306	21	-	26627737	RPE1	viability after 12 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-0.1682317806476285	[580]	[84,195]	-1	hSpCas9	negative selection	1227645
33755304	33755327	21	-	26627737	RPE1	viability after 12 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	0.0746882833683592	[607]	[274,62]	0	hSpCas9	negative selection	1227646
33761954	33761977	21	+	26627737	RPE1	viability after 12 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	-0.3165456830605927	[767]	[171,158]	-2	hSpCas9	negative selection	1227647
33772269	33772292	21	+	26627737	RPE1	viability after 12 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.5136215439155842	[1920]	[242,486]	-4	hSpCas9	negative selection	1227648
33775011	33775034	21	+	26627737	RPE1	viability after 12 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	-1.0645647355254955	[364]	[59,32]	-6	hSpCas9	negative selection	1227649
33735155	33735178	21	-	26627737	RPE1	viability after 15 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	-0.1859371197457529	[2306]	[506,637]	-1	hSpCas9	negative selection	1309959
33750283	33750306	21	-	26627737	RPE1	viability after 15 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-0.21050765046811276	[580]	[167,116]	-1	hSpCas9	negative selection	1309960
33755304	33755327	21	-	26627737	RPE1	viability after 15 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	0.7596722132700212	[607]	[476,111]	5	hSpCas9	negative selection	1309961
33761954	33761977	21	+	26627737	RPE1	viability after 15 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	-0.29459419087710215	[767]	[141,210]	-2	hSpCas9	negative selection	1309962
33772269	33772292	21	+	26627737	RPE1	viability after 15 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-1.2137020754714263	[1920]	[76,385]	-6	hSpCas9	negative selection	1309963
33775011	33775034	21	+	26627737	RPE1	viability after 15 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	-0.8378874068311317	[364]	[70,44]	-5	hSpCas9	negative selection	1309964
33735155	33735178	21	-	26627737	RPE1	viability after 18 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	-0.08845102488725609	[2306]	[499,676]	0	hSpCas9	negative selection	1392274
33750283	33750306	21	-	26627737	RPE1	viability after 18 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-0.2294971644318337	[580]	[125,141]	-1	hSpCas9	negative selection	1392275
33755304	33755327	21	-	26627737	RPE1	viability after 18 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	0.06943587937430601	[607]	[249,88]	0	hSpCas9	negative selection	1392276
33761954	33761977	21	+	26627737	RPE1	viability after 18 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	-0.5760088786159329	[767]	[139,137]	-4	hSpCas9	negative selection	1392277
33772269	33772292	21	+	26627737	RPE1	viability after 18 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.9413098971213814	[1920]	[239,301]	-5	hSpCas9	negative selection	1392278
33775011	33775034	21	+	26627737	RPE1	viability after 18 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	-1.302037814897492	[364]	[52,25]	-7	hSpCas9	negative selection	1392279
33735155	33735178	21	-	26627737	HeLa	viability after 8 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.4722142210811203	[694]	[512,462,310]	4	hSpCas9	negative selection	1474589
33750283	33750306	21	-	26627737	HeLa	viability after 8 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-0.04360515362108919	[339]	[192,215,39]	0	hSpCas9	negative selection	1474590
33755304	33755327	21	-	26627737	HeLa	viability after 8 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	3.7745697818796167	[9]	[0,167,0]	9	hSpCas9	negative selection	1474591
33761954	33761977	21	+	26627737	HeLa	viability after 8 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.5003106606389971	[284]	[215,140,177]	4	hSpCas9	negative selection	1474592
33772269	33772292	21	+	26627737	HeLa	viability after 8 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.025124421965168953	[988]	[451,723,120]	0	hSpCas9	negative selection	1474593
33775011	33775034	21	+	26627737	HeLa	viability after 8 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	-0.018624767294469047	[133]	[105,73,6]	0	hSpCas9	negative selection	1474594
33735155	33735178	21	-	26627737	HeLa	viability after 12 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.9163696444269606	[694]	[468,599,548]	7	hSpCas9	negative selection	1556904
33750283	33750306	21	-	26627737	HeLa	viability after 12 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-0.07534352703546393	[339]	[205,87,112]	0	hSpCas9	negative selection	1556905
33755304	33755327	21	-	26627737	HeLa	viability after 12 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	2.228982338975704	[9]	[16,0,41]	9	hSpCas9	negative selection	1556906
33761954	33761977	21	+	26627737	HeLa	viability after 12 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.42538073507018004	[284]	[197,88,195]	3	hSpCas9	negative selection	1556907
33772269	33772292	21	+	26627737	HeLa	viability after 12 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.15753646956109502	[988]	[413,306,385]	-1	hSpCas9	negative selection	1556908
33775011	33775034	21	+	26627737	HeLa	viability after 12 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.42009692155408107	[133]	[102,46,75]	3	hSpCas9	negative selection	1556909
33735155	33735178	21	-	26627737	HeLa	viability after 15 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.6259985955606181	[694]	[459,444,401]	5	hSpCas9	negative selection	1639219
33750283	33750306	21	-	26627737	HeLa	viability after 15 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-0.6031179880428346	[339]	[138,99,28]	-5	hSpCas9	negative selection	1639220
33755304	33755327	21	-	26627737	HeLa	viability after 15 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	4.537122165211798	[9]	[65,206,3]	9	hSpCas9	negative selection	1639221
33761954	33761977	21	+	26627737	HeLa	viability after 15 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	-0.6618932928468484	[284]	[63,47,110]	-5	hSpCas9	negative selection	1639222
33772269	33772292	21	+	26627737	HeLa	viability after 15 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.6046603321918612	[988]	[448,137,199]	-5	hSpCas9	negative selection	1639223
33775011	33775034	21	+	26627737	HeLa	viability after 15 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	1.2147689660987204	[133]	[47,107,232]	8	hSpCas9	negative selection	1639224
33735155	33735178	21	-	26627737	HeLa	viability after 18 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.6078420707658746	[694]	[299,365,401]	5	hSpCas9	negative selection	1721534
33750283	33750306	21	-	26627737	HeLa	viability after 18 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-0.5433796851382349	[339]	[102,79,28]	-5	hSpCas9	negative selection	1721535
33755304	33755327	21	-	26627737	HeLa	viability after 18 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	4.598534342865593	[9]	[46,177,3]	9	hSpCas9	negative selection	1721536
33761954	33761977	21	+	26627737	HeLa	viability after 18 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	-0.6057364972014758	[284]	[45,42,110]	-5	hSpCas9	negative selection	1721537
33772269	33772292	21	+	26627737	HeLa	viability after 18 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.6009633965556791	[988]	[305,109,199]	-5	hSpCas9	negative selection	1721538
33775011	33775034	21	+	26627737	HeLa	viability after 18 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	1.2127298969301534	[133]	[32,87,232]	8	hSpCas9	negative selection	1721539
33735155	33735178	21	-	26627737	HCT116	viability after 6 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.11729513838454175	[1114]	[329,112]	0	hSpCas9	negative selection	1803849
33750283	33750306	21	-	26627737	HCT116	viability after 6 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-1.3366891862833812	[637]	[40,38]	-6	hSpCas9	negative selection	1803850
33755304	33755327	21	-	26627737	HCT116	viability after 6 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	2.235600396033562	[185]	[2,211]	9	hSpCas9	negative selection	1803851
33761954	33761977	21	+	26627737	HCT116	viability after 6 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	-1.9995135385249454	[906]	[83,8]	-8	hSpCas9	negative selection	1803852
33772269	33772292	21	+	26627737	HCT116	viability after 6 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	1.0440258144643981	[918]	[226,336]	5	hSpCas9	negative selection	1803853
33775011	33775034	21	+	26627737	HCT116	viability after 6 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	2.227460220488832	[163]	[83,140]	9	hSpCas9	negative selection	1803854
33735155	33735178	21	-	26627737	HCT116	viability after 8 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.9252609804959088	[365]	[426,442,280]	8	hSpCas9	negative selection	1886164
33750283	33750306	21	-	26627737	HCT116	viability after 8 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-1.0461861771187073	[429]	[93,147,101]	-8	hSpCas9	negative selection	1886165
33755304	33755327	21	-	26627737	HCT116	viability after 8 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-0.3150970580228931	[88]	[34,28,53]	-4	hSpCas9	negative selection	1886166
33761954	33761977	21	+	26627737	HCT116	viability after 8 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.43172590414858647	[143]	[102,109,107]	4	hSpCas9	negative selection	1886167
33772269	33772292	21	+	26627737	HCT116	viability after 8 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	0.22771556464036247	[449]	[242,317,308]	2	hSpCas9	negative selection	1886168
33775011	33775034	21	+	26627737	HCT116	viability after 8 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	-0.043323157320614536	[126]	[46,58,96]	0	hSpCas9	negative selection	1886169
33735155	33735178	21	-	26627737	HCT116	viability after 9 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.7565505666514956	[1114]	[607,419]	5	hSpCas9	negative selection	1968479
33750283	33750306	21	-	26627737	HCT116	viability after 9 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-1.6108819248183441	[637]	[76,38]	-8	hSpCas9	negative selection	1968480
33755304	33755327	21	-	26627737	HCT116	viability after 9 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-0.6410903664079075	[185]	[18,41]	-4	hSpCas9	negative selection	1968481
33761954	33761977	21	+	26627737	HCT116	viability after 9 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	-1.4674957792508159	[906]	[186,8]	-7	hSpCas9	negative selection	1968482
33772269	33772292	21	+	26627737	HCT116	viability after 9 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.24093056724589124	[918]	[334,106]	-2	hSpCas9	negative selection	1968483
33775011	33775034	21	+	26627737	HCT116	viability after 9 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.6743050266926627	[163]	[70,68]	5	hSpCas9	negative selection	1968484
33735155	33735178	21	-	26627737	HCT116	viability after 12 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.8233585430566642	[365]	[329,423,269]	7	hSpCas9	negative selection	2050794
33750283	33750306	21	-	26627737	HCT116	viability after 12 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-1.350776593112545	[429]	[42,178,49]	-8	hSpCas9	negative selection	2050795
33755304	33755327	21	-	26627737	HCT116	viability after 12 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	0.14612439661132348	[88]	[72,34,44]	1	hSpCas9	negative selection	2050796
33761954	33761977	21	+	26627737	HCT116	viability after 12 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	1.1189397175719356	[143]	[153,164,174]	8	hSpCas9	negative selection	2050797
33772269	33772292	21	+	26627737	HCT116	viability after 12 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	0.13938573281389255	[449]	[233,311,238]	1	hSpCas9	negative selection	2050798
33775011	33775034	21	+	26627737	HCT116	viability after 12 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.19244341651661534	[126]	[27,115,89]	2	hSpCas9	negative selection	2050799
33735155	33735178	21	-	26627737	HCT116	viability after 15 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.9760417524220447	[365]	[416,508,315]	8	hSpCas9	negative selection	2133109
33750283	33750306	21	-	26627737	HCT116	viability after 15 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-1.0839476955354395	[429]	[116,153,78]	-8	hSpCas9	negative selection	2133110
33755304	33755327	21	-	26627737	HCT116	viability after 15 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-0.18644841129440204	[88]	[45,53,34]	-2	hSpCas9	negative selection	2133111
33761954	33761977	21	+	26627737	HCT116	viability after 15 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.8657782288081872	[143]	[181,129,143]	7	hSpCas9	negative selection	2133112
33772269	33772292	21	+	26627737	HCT116	viability after 15 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	0.5213578957916346	[449]	[434,431,254]	5	hSpCas9	negative selection	2133113
33775011	33775034	21	+	26627737	HCT116	viability after 15 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.0030182582256081947	[126]	[20,124,66]	0	hSpCas9	negative selection	2133114
33735155	33735178	21	-	26627737	HCT116	viability after 18 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.758000320366874	[365]	[240,431,211]	6	hSpCas9	negative selection	2215424
33750283	33750306	21	-	26627737	HCT116	viability after 18 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-0.8345974258609167	[429]	[39,213,87]	-6	hSpCas9	negative selection	2215425
33755304	33755327	21	-	26627737	HCT116	viability after 18 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-0.16072517044556345	[88]	[51,36,25]	-1	hSpCas9	negative selection	2215426
33761954	33761977	21	+	26627737	HCT116	viability after 18 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.3960516990871241	[143]	[108,82,82]	3	hSpCas9	negative selection	2215427
33772269	33772292	21	+	26627737	HCT116	viability after 18 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	0.5049701948292012	[449]	[128,503,278]	4	hSpCas9	negative selection	2215428
33775011	33775034	21	+	26627737	HCT116	viability after 18 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.22529649135001772	[126]	[69,100,40]	2	hSpCas9	negative selection	2215429
33666874	33666897	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAGCCTCGACTTCTGGG	ITSN1	ENSG00000205726	-0.3334344553746127	[914,176]	[125,59]	-1	dCas9-VP64	positive selection	2383763
33833826	33833849	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGTGCCACTGCACTCCAGCCGGG	ITSN1	ENSG00000205726	0.4846974014178431	[92,26]	[27,6]	2	dCas9-VP64	positive selection	2390980
33729497	33729520	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	AACCAAAAAGTATCTGAGACAAG	ITSN1	ENSG00000205726	0.8269210336232619	[39,55]	[18,16]	3	dCas9-VP64	positive selection	2395369
33648652	33648675	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTCTTGCTATGTTGCCCTGG	ITSN1	ENSG00000205726	0.7258925451918798	[40,76]	[27,13]	3	dCas9-VP64	positive selection	2423545
33833844	33833867	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCGCTCTGTCACCCCGG	ITSN1	ENSG00000205726	2.045058343104601	[17,78]	[6,84]	7	dCas9-VP64	positive selection	2429003
33742119	33742142	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGTTGCAGTGAGCCGAGAAGG	ITSN1	ENSG00000205726	0.6330757747468561	[50,16]	[8,13]	2	dCas9-VP64	positive selection	2476948
33869473	33869496	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTACAATTCAAGATGAGATTTGG	ITSN1	ENSG00000205726	-2.0010020361462013	[696,629]	[34,36]	-9	dCas9-VP64	positive selection	2478194
33666874	33666897	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAGCCTCGACTTCTGGG	ITSN1	ENSG00000205726	-0.34054073104189286	[370,392]	[107,88]	-3	dCas9-VP64	positive selection	2479018
33833826	33833849	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGTGCCACTGCACTCCAGCCGGG	ITSN1	ENSG00000205726	0.6971910689480432	[49,47]	[24,25]	5	dCas9-VP64	positive selection	2486235
33729497	33729520	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	AACCAAAAAGTATCTGAGACAAG	ITSN1	ENSG00000205726	4.518269774264655	[235,157]	[3047,16]	9	dCas9-VP64	positive selection	2490624
33648652	33648675	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTCTTGCTATGTTGCCCTGG	ITSN1	ENSG00000205726	-0.28323094604648114	[112,110]	[38,20]	-3	dCas9-VP64	positive selection	2518800
33833844	33833867	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCGCTCTGTCACCCCGG	ITSN1	ENSG00000205726	0.8120885956412129	[203,131]	[135,58]	5	dCas9-VP64	positive selection	2524258
33742119	33742142	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGTTGCAGTGAGCCGAGAAGG	ITSN1	ENSG00000205726	0.34517561365305327	[29,16]	[7,9]	2	dCas9-VP64	positive selection	2572203
33869473	33869496	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTACAATTCAAGATGAGATTTGG	ITSN1	ENSG00000205726	-0.023705952056314983	[265,419]	[72,143]	0	dCas9-VP64	positive selection	2573449
33813938	33813961	21	-	27260157	DLD1	viability	GCATCCCAGTTATCCGTTTCTGG	ITSN1	ENSG00000205726	0.662462758272183	[]	[]	8	hSpCas9	negative selection	2576949
33811192	33811215	21	-	27260157	DLD1	viability	GAAGTCGGCCCAGTTATTAGGGG	ITSN1	ENSG00000205726	-0.426848934818597	[]	[]	-4	hSpCas9	negative selection	2579713
33772194	33772217	21	+	27260157	DLD1	viability	GAGGAAGGAGCGTGAGCGCCAGG	ITSN1	ENSG00000205726	0.612590816359464	[]	[]	8	hSpCas9	negative selection	2579739
33721196	33721219	21	-	27260157	DLD1	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	1.17037497369382	[]	[]	9	hSpCas9	negative selection	2581903
33782046	33782069	21	+	27260157	DLD1	viability	GCAGCACCTACGAGACCAACTGG	ITSN1	ENSG00000205726	1.88118447542797	[]	[]	9	hSpCas9	negative selection	2582573
33767711	33767734	21	+	27260157	DLD1	viability	AGAAGAGTTCGATCTGGCAGTGG	ITSN1	ENSG00000205726	-0.182576522013209	[]	[]	-1	hSpCas9	negative selection	2582831
33814015	33814038	21	+	27260157	DLD1	viability	GTCCGCCTTTACTCCAGCCACGG	ITSN1	ENSG00000205726	0.4565175315092	[]	[]	7	hSpCas9	negative selection	2586538
33721188	33721211	21	+	27260157	DLD1	viability	TATCTGGGCCATAACTGTAGAGG	ITSN1	ENSG00000205726	0.224984971072175	[]	[]	3	hSpCas9	negative selection	2609781
33811207	33811230	21	-	27260157	DLD1	viability	CACGTACGTGGAGCTGAAGTCGG	ITSN1	ENSG00000205726	0.886388908261191	[]	[]	9	hSpCas9	negative selection	2609924
33814017	33814040	21	-	27260157	DLD1	viability	GGCCGTGGCTGGAGTAAAGGCGG	ITSN1	ENSG00000205726	1.48153103535285	[]	[]	9	hSpCas9	negative selection	2615893
33775011	33775034	21	+	27260157	DLD1	viability	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.841951809643904	[]	[]	9	hSpCas9	negative selection	2616453
33772078	33772101	21	+	27260157	DLD1	viability	AAGCGGGAGAACTTTGAACGTGG	ITSN1	ENSG00000205726	0.155050342214097	[]	[]	3	hSpCas9	negative selection	2622655
33774763	33774786	21	+	27260157	DLD1	viability	TTGAGTGGGAACGGAATCGAAGG	ITSN1	ENSG00000205726	0.193470831789414	[]	[]	3	hSpCas9	negative selection	2623682
33751834	33751857	21	-	27260157	DLD1	viability	CCCTGGACCAGATCTACTAAAGG	ITSN1	ENSG00000205726	1.03336461071506	[]	[]	9	hSpCas9	negative selection	2623904
33810985	33811008	21	+	27260157	DLD1	viability	GCCAAACTGGAGAACCCGGCTGG	ITSN1	ENSG00000205726	0.326823171218433	[]	[]	4	hSpCas9	negative selection	2644513
33782052	33782075	21	-	27260157	DLD1	viability	CTTCATCCAGTTGGTCTCGTAGG	ITSN1	ENSG00000205726	0.448317781684277	[]	[]	7	hSpCas9	negative selection	2645648
33813917	33813940	21	-	27260157	DLD1	viability	GGTTTCTCATTCGTGCTGGTGGG	ITSN1	ENSG00000205726	0.671160591122138	[]	[]	8	hSpCas9	negative selection	2645841
33750158	33750181	21	-	27260157	DLD1	viability	AGCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-0.857851275252713	[]	[]	-6	hSpCas9	negative selection	2649054
33813938	33813961	21	-	27260157	HT1080	viability	GCATCCCAGTTATCCGTTTCTGG	ITSN1	ENSG00000205726	-0.119440183649834	[]	[]	0	hSpCas9	negative selection	2653079
33811192	33811215	21	-	27260157	HT1080	viability	GAAGTCGGCCCAGTTATTAGGGG	ITSN1	ENSG00000205726	0.404300792056867	[]	[]	3	hSpCas9	negative selection	2655843
33772194	33772217	21	+	27260157	HT1080	viability	GAGGAAGGAGCGTGAGCGCCAGG	ITSN1	ENSG00000205726	0.889959520189018	[]	[]	7	hSpCas9	negative selection	2655869
33721196	33721219	21	-	27260157	HT1080	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.255191992534398	[]	[]	2	hSpCas9	negative selection	2658033
33782046	33782069	21	+	27260157	HT1080	viability	GCAGCACCTACGAGACCAACTGG	ITSN1	ENSG00000205726	1.34071600499796	[]	[]	9	hSpCas9	negative selection	2658703
33767711	33767734	21	+	27260157	HT1080	viability	AGAAGAGTTCGATCTGGCAGTGG	ITSN1	ENSG00000205726	0.620561616215616	[]	[]	5	hSpCas9	negative selection	2658961
33814015	33814038	21	+	27260157	HT1080	viability	GTCCGCCTTTACTCCAGCCACGG	ITSN1	ENSG00000205726	0.0875185358701342	[]	[]	1	hSpCas9	negative selection	2662668
33721188	33721211	21	+	27260157	HT1080	viability	TATCTGGGCCATAACTGTAGAGG	ITSN1	ENSG00000205726	0.352580915335145	[]	[]	3	hSpCas9	negative selection	2685911
33811207	33811230	21	-	27260157	HT1080	viability	CACGTACGTGGAGCTGAAGTCGG	ITSN1	ENSG00000205726	-0.32423394038495	[]	[]	-7	hSpCas9	negative selection	2686054
33814017	33814040	21	-	27260157	HT1080	viability	GGCCGTGGCTGGAGTAAAGGCGG	ITSN1	ENSG00000205726	-0.468146136659004	[]	[]	-7	hSpCas9	negative selection	2692023
33775011	33775034	21	+	27260157	HT1080	viability	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.296570779610023	[]	[]	3	hSpCas9	negative selection	2692583
33772078	33772101	21	+	27260157	HT1080	viability	AAGCGGGAGAACTTTGAACGTGG	ITSN1	ENSG00000205726	0.458637106808455	[]	[]	4	hSpCas9	negative selection	2698785
33774763	33774786	21	+	27260157	HT1080	viability	TTGAGTGGGAACGGAATCGAAGG	ITSN1	ENSG00000205726	-0.798368071097692	[]	[]	-8	hSpCas9	negative selection	2699812
33751834	33751857	21	-	27260157	HT1080	viability	CCCTGGACCAGATCTACTAAAGG	ITSN1	ENSG00000205726	0.460300245580718	[]	[]	4	hSpCas9	negative selection	2700034
33810985	33811008	21	+	27260157	HT1080	viability	GCCAAACTGGAGAACCCGGCTGG	ITSN1	ENSG00000205726	1.10650156361695	[]	[]	8	hSpCas9	negative selection	2720643
33782052	33782075	21	-	27260157	HT1080	viability	CTTCATCCAGTTGGTCTCGTAGG	ITSN1	ENSG00000205726	0.254492667063786	[]	[]	2	hSpCas9	negative selection	2721778
33813917	33813940	21	-	27260157	HT1080	viability	GGTTTCTCATTCGTGCTGGTGGG	ITSN1	ENSG00000205726	0.502312241218196	[]	[]	4	hSpCas9	negative selection	2721971
33750158	33750181	21	-	27260157	HT1080	viability	AGCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-0.604404834482349	[]	[]	-8	hSpCas9	negative selection	2725184
33813938	33813961	21	-	27260157	MKN45	viability	GCATCCCAGTTATCCGTTTCTGG	ITSN1	ENSG00000205726	-0.442027501920238	[]	[]	-6	hSpCas9	negative selection	2729209
33811192	33811215	21	-	27260157	MKN45	viability	GAAGTCGGCCCAGTTATTAGGGG	ITSN1	ENSG00000205726	0.11811354587355	[]	[]	4	hSpCas9	negative selection	2731973
33772194	33772217	21	+	27260157	MKN45	viability	GAGGAAGGAGCGTGAGCGCCAGG	ITSN1	ENSG00000205726	0.963253264377857	[]	[]	8	hSpCas9	negative selection	2731999
33721196	33721219	21	-	27260157	MKN45	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.767263239646873	[]	[]	7	hSpCas9	negative selection	2734163
33782046	33782069	21	+	27260157	MKN45	viability	GCAGCACCTACGAGACCAACTGG	ITSN1	ENSG00000205726	1.50011813062898	[]	[]	9	hSpCas9	negative selection	2734833
33767711	33767734	21	+	27260157	MKN45	viability	AGAAGAGTTCGATCTGGCAGTGG	ITSN1	ENSG00000205726	0.232859753843683	[]	[]	5	hSpCas9	negative selection	2735091
33814015	33814038	21	+	27260157	MKN45	viability	GTCCGCCTTTACTCCAGCCACGG	ITSN1	ENSG00000205726	0.170200932032597	[]	[]	5	hSpCas9	negative selection	2738798
33721188	33721211	21	+	27260157	MKN45	viability	TATCTGGGCCATAACTGTAGAGG	ITSN1	ENSG00000205726	-1.19437996281851	[]	[]	-8	hSpCas9	negative selection	2762041
33811207	33811230	21	-	27260157	MKN45	viability	CACGTACGTGGAGCTGAAGTCGG	ITSN1	ENSG00000205726	-0.025406843616772	[]	[]	0	hSpCas9	negative selection	2762184
33814017	33814040	21	-	27260157	MKN45	viability	GGCCGTGGCTGGAGTAAAGGCGG	ITSN1	ENSG00000205726	0.3305441324585	[]	[]	6	hSpCas9	negative selection	2768153
33775011	33775034	21	+	27260157	MKN45	viability	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	-0.189583702140043	[]	[]	0	hSpCas9	negative selection	2768713
33772078	33772101	21	+	27260157	MKN45	viability	AAGCGGGAGAACTTTGAACGTGG	ITSN1	ENSG00000205726	0.457498249040943	[]	[]	6	hSpCas9	negative selection	2774915
33774763	33774786	21	+	27260157	MKN45	viability	TTGAGTGGGAACGGAATCGAAGG	ITSN1	ENSG00000205726	0.0897799171991472	[]	[]	0	hSpCas9	negative selection	2775942
33751834	33751857	21	-	27260157	MKN45	viability	CCCTGGACCAGATCTACTAAAGG	ITSN1	ENSG00000205726	0.5884441679942	[]	[]	7	hSpCas9	negative selection	2776164
33810985	33811008	21	+	27260157	MKN45	viability	GCCAAACTGGAGAACCCGGCTGG	ITSN1	ENSG00000205726	0.840767394472194	[]	[]	8	hSpCas9	negative selection	2796773
33782052	33782075	21	-	27260157	MKN45	viability	CTTCATCCAGTTGGTCTCGTAGG	ITSN1	ENSG00000205726	-0.644179365430012	[]	[]	-7	hSpCas9	negative selection	2797908
33813917	33813940	21	-	27260157	MKN45	viability	GGTTTCTCATTCGTGCTGGTGGG	ITSN1	ENSG00000205726	0.364485388797538	[]	[]	6	hSpCas9	negative selection	2798101
33750158	33750181	21	-	27260157	MKN45	viability	AGCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	0.436842401717108	[]	[]	6	hSpCas9	negative selection	2801314
33813938	33813961	21	-	27260157	RKO	viability	GCATCCCAGTTATCCGTTTCTGG	ITSN1	ENSG00000205726	-0.611363940290788	[]	[]	-7	hSpCas9	negative selection	2805339
33811192	33811215	21	-	27260157	RKO	viability	GAAGTCGGCCCAGTTATTAGGGG	ITSN1	ENSG00000205726	1.45058082039633	[]	[]	9	hSpCas9	negative selection	2808103
33772194	33772217	21	+	27260157	RKO	viability	GAGGAAGGAGCGTGAGCGCCAGG	ITSN1	ENSG00000205726	1.53244778855177	[]	[]	9	hSpCas9	negative selection	2808129
33721196	33721219	21	-	27260157	RKO	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.411002485882418	[]	[]	2	hSpCas9	negative selection	2810293
33782046	33782069	21	+	27260157	RKO	viability	GCAGCACCTACGAGACCAACTGG	ITSN1	ENSG00000205726	1.36759112969902	[]	[]	9	hSpCas9	negative selection	2810963
33767711	33767734	21	+	27260157	RKO	viability	AGAAGAGTTCGATCTGGCAGTGG	ITSN1	ENSG00000205726	0.523345656583874	[]	[]	2	hSpCas9	negative selection	2811221
33814015	33814038	21	+	27260157	RKO	viability	GTCCGCCTTTACTCCAGCCACGG	ITSN1	ENSG00000205726	0.335767656046433	[]	[]	1	hSpCas9	negative selection	2814928
33721188	33721211	21	+	27260157	RKO	viability	TATCTGGGCCATAACTGTAGAGG	ITSN1	ENSG00000205726	-0.431043184186708	[]	[]	-6	hSpCas9	negative selection	2838171
33811207	33811230	21	-	27260157	RKO	viability	CACGTACGTGGAGCTGAAGTCGG	ITSN1	ENSG00000205726	-0.18353224497967	[]	[]	-1	hSpCas9	negative selection	2838314
33814017	33814040	21	-	27260157	RKO	viability	GGCCGTGGCTGGAGTAAAGGCGG	ITSN1	ENSG00000205726	-1.35920951972815	[]	[]	-8	hSpCas9	negative selection	2844283
33775011	33775034	21	+	27260157	RKO	viability	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.593361476522542	[]	[]	3	hSpCas9	negative selection	2844843
33772078	33772101	21	+	27260157	RKO	viability	AAGCGGGAGAACTTTGAACGTGG	ITSN1	ENSG00000205726	0.440066699368534	[]	[]	2	hSpCas9	negative selection	2851045
33774763	33774786	21	+	27260157	RKO	viability	TTGAGTGGGAACGGAATCGAAGG	ITSN1	ENSG00000205726	-0.100247961607744	[]	[]	0	hSpCas9	negative selection	2852072
33751834	33751857	21	-	27260157	RKO	viability	CCCTGGACCAGATCTACTAAAGG	ITSN1	ENSG00000205726	0.257528614178911	[]	[]	1	hSpCas9	negative selection	2852294
33810985	33811008	21	+	27260157	RKO	viability	GCCAAACTGGAGAACCCGGCTGG	ITSN1	ENSG00000205726	0.792847958695122	[]	[]	8	hSpCas9	negative selection	2872903
33782052	33782075	21	-	27260157	RKO	viability	CTTCATCCAGTTGGTCTCGTAGG	ITSN1	ENSG00000205726	0.0973940749031103	[]	[]	0	hSpCas9	negative selection	2874038
33813917	33813940	21	-	27260157	RKO	viability	GGTTTCTCATTCGTGCTGGTGGG	ITSN1	ENSG00000205726	1.03312545049483	[]	[]	9	hSpCas9	negative selection	2874231
33750158	33750181	21	-	27260157	RKO	viability	AGCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	0.183828379754562	[]	[]	1	hSpCas9	negative selection	2877444
33813938	33813961	21	-	27260157	SF268	viability	GCATCCCAGTTATCCGTTTCTGG	ITSN1	ENSG00000205726	0.285615479566142	[]	[]	4	hSpCas9	negative selection	2881469
33811192	33811215	21	-	27260157	SF268	viability	GAAGTCGGCCCAGTTATTAGGGG	ITSN1	ENSG00000205726	0.599741792079724	[]	[]	8	hSpCas9	negative selection	2884233
33772194	33772217	21	+	27260157	SF268	viability	GAGGAAGGAGCGTGAGCGCCAGG	ITSN1	ENSG00000205726	0.462114444458179	[]	[]	7	hSpCas9	negative selection	2884259
33721196	33721219	21	-	27260157	SF268	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	-0.27684440747836	[]	[]	-2	hSpCas9	negative selection	2886423
33782046	33782069	21	+	27260157	SF268	viability	GCAGCACCTACGAGACCAACTGG	ITSN1	ENSG00000205726	2.6194135845431	[]	[]	9	hSpCas9	negative selection	2887093
33767711	33767734	21	+	27260157	SF268	viability	AGAAGAGTTCGATCTGGCAGTGG	ITSN1	ENSG00000205726	0.56326242172001	[]	[]	8	hSpCas9	negative selection	2887351
33814015	33814038	21	+	27260157	SF268	viability	GTCCGCCTTTACTCCAGCCACGG	ITSN1	ENSG00000205726	0.416479300509353	[]	[]	4	hSpCas9	negative selection	2891058
33721188	33721211	21	+	27260157	SF268	viability	TATCTGGGCCATAACTGTAGAGG	ITSN1	ENSG00000205726	0.25464461147698	[]	[]	4	hSpCas9	negative selection	2914301
33811207	33811230	21	-	27260157	SF268	viability	CACGTACGTGGAGCTGAAGTCGG	ITSN1	ENSG00000205726	-0.491087196548896	[]	[]	-4	hSpCas9	negative selection	2914444
33814017	33814040	21	-	27260157	SF268	viability	GGCCGTGGCTGGAGTAAAGGCGG	ITSN1	ENSG00000205726	-0.0961144216122737	[]	[]	0	hSpCas9	negative selection	2920413
33775011	33775034	21	+	27260157	SF268	viability	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.299899821103034	[]	[]	4	hSpCas9	negative selection	2920973
33772078	33772101	21	+	27260157	SF268	viability	AAGCGGGAGAACTTTGAACGTGG	ITSN1	ENSG00000205726	0.49794609218265	[]	[]	7	hSpCas9	negative selection	2927175
33774763	33774786	21	+	27260157	SF268	viability	TTGAGTGGGAACGGAATCGAAGG	ITSN1	ENSG00000205726	-0.489411874443437	[]	[]	-4	hSpCas9	negative selection	2928202
33751834	33751857	21	-	27260157	SF268	viability	CCCTGGACCAGATCTACTAAAGG	ITSN1	ENSG00000205726	0.955334291667354	[]	[]	9	hSpCas9	negative selection	2928424
33810985	33811008	21	+	27260157	SF268	viability	GCCAAACTGGAGAACCCGGCTGG	ITSN1	ENSG00000205726	0.325641452368124	[]	[]	4	hSpCas9	negative selection	2949033
33782052	33782075	21	-	27260157	SF268	viability	CTTCATCCAGTTGGTCTCGTAGG	ITSN1	ENSG00000205726	-0.0919467919490803	[]	[]	0	hSpCas9	negative selection	2950168
33813917	33813940	21	-	27260157	SF268	viability	GGTTTCTCATTCGTGCTGGTGGG	ITSN1	ENSG00000205726	0.211543681115975	[]	[]	3	hSpCas9	negative selection	2950361
33750158	33750181	21	-	27260157	SF268	viability	AGCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	0.214330721611598	[]	[]	3	hSpCas9	negative selection	2953574
33751835	33751858	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTTAGTAGATCTGGTCCAGGG	ITSN1	ENSG00000205726	-0.1538704035179922	[4,4]	[4,2]	-2	hSpCas9	positive selection	2996283
33750179	33750202	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGTTGCTCCAGTGCCAATGGG	ITSN1	ENSG00000205726	-0.311114829998819	[3,4]	[2,2]	-4	hSpCas9	positive selection	2996284
33735174	33735197	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	-0.008239619965056205	[3,4]	[3,3]	0	hSpCas9	positive selection	2996285
33735153	33735176	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTTGCTGTTTCATGACAGGGGG	ITSN1	ENSG00000205726	0.1464934796857491	[5,5]	[5,4]	3	hSpCas9	positive selection	2996286
33751835	33751858	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTTAGTAGATCTGGTCCAGGG	ITSN1	ENSG00000205726	0.3122534156309195	[4,4]	[4,3]	5	hSpCas9	positive selection	3064141
33750179	33750202	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGTTGCTCCAGTGCCAATGGG	ITSN1	ENSG00000205726	-0.13037803228306832	[3,3]	[3,1]	-2	hSpCas9	positive selection	3064142
33735174	33735197	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	-0.18205001422328687	[3,3]	[3,1]	-3	hSpCas9	positive selection	3064143
33735153	33735176	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTTGCTGTTTCATGACAGGGGG	ITSN1	ENSG00000205726	0.40964179850596727	[5,5]	[6,4]	7	hSpCas9	positive selection	3064144
33722630	33722653		+	24336571	A375	resistance to PLX after 7 days	AACCTGTTTTAGCACAGATATGG	ITSN1	ENSG00000205726	-0.08895081939732974	[21,21]	[16,22]	-3	hSpCas9	positive selection	3121915
33721249	33721272		-	24336571	A375	resistance to PLX after 7 days	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.3077941938062624	[20,30]	[19,21]	-8	hSpCas9	positive selection	3121917
33721196	33721219		-	24336571	A375	resistance to PLX after 7 days	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.024673267384333508	[30,31]	[30,32]	0	hSpCas9	positive selection	3121918
33722632	33722655		-	24336571	A375	resistance to PLX after 7 days	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.09751892674470408	[5,9]	[8,7]	3	hSpCas9	positive selection	3121919
33722630	33722653		+	24336571	A375	resistance to PLX after 14 days	AACCTGTTTTAGCACAGATATGG	ITSN1	ENSG00000205726	0.2882598032211785	[21,19]	[9,12]	3	hSpCas9	positive selection	3179708
33721249	33721272		-	24336571	A375	resistance to PLX after 14 days	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.8050231893134072	[26,35]	[8,6]	-8	hSpCas9	positive selection	3179710
33721196	33721219		-	24336571	A375	resistance to PLX after 14 days	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.3190278977208527	[25,28]	[13,17]	3	hSpCas9	positive selection	3179711
33722632	33722655		-	24336571	A375	resistance to PLX after 14 days	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.554058191318435	[6,6]	[4,3]	5	hSpCas9	positive selection	3179712
33722630	33722653		+	24336571	A375	viability after 7 days	AACCTGTTTTAGCACAGATATGG	ITSN1	ENSG00000205726	0.4757033196946406	[15]	[21,21]	7	hSpCas9	negative selection	3237501
33721249	33721272		-	24336571	A375	viability after 7 days	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	0.028578142906833914	[26]	[20,30]	0	hSpCas9	negative selection	3237503
33721196	33721219		-	24336571	A375	viability after 7 days	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.6376517771308804	[20]	[30,31]	8	hSpCas9	negative selection	3237504
33722632	33722655		-	24336571	A375	viability after 7 days	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-1.100641999544549	[17]	[5,9]	-9	hSpCas9	negative selection	3237505
33722630	33722653		+	24336571	A375	viability after 14 days	AACCTGTTTTAGCACAGATATGG	ITSN1	ENSG00000205726	0.4349255482631638	[15]	[21,19]	5	hSpCas9	negative selection	3295294
33721249	33721272		-	24336571	A375	viability after 14 days	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	0.2864003670946038	[26]	[26,35]	4	hSpCas9	negative selection	3295296
33721196	33721219		-	24336571	A375	viability after 14 days	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.4455331078997834	[20]	[25,28]	5	hSpCas9	negative selection	3295297
33722632	33722655		-	24336571	A375	viability after 14 days	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-1.2404224003819189	[17]	[6,6]	-9	hSpCas9	negative selection	3295298
33721249	33721272	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-1.0000616312468167	[305,305]	[0,0]	-6	hSpCas9	positive selection	3374877
33722632	33722655	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.23495839841738073	[129,129]	[0,0]	1	hSpCas9	positive selection	3374878
33721237	33721260	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	-0.009460329249066228	[153,153]	[0,0]	0	hSpCas9	positive selection	3374879
33751834	33751857	21	+	26780180	HT29	viability (Avana library 4 designs)	CCTTTAGTAGATCTGGTCCAGGG	ITSN1	ENSG00000205726	-0.170856905819117	[]	[]	-3	hSpCas9	negative selection	3433681
33750178	33750201	21	+	26780180	HT29	viability (Avana library 4 designs)	GCTGTTGCTCCAGTGCCAATGGG	ITSN1	ENSG00000205726	0.207424326543676	[]	[]	0	hSpCas9	negative selection	3433682
33735174	33735197	21	-	26780180	HT29	viability (Avana library 4 designs)	GGTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	1.14350634501009	[]	[]	4	hSpCas9	negative selection	3433683
33735153	33735176	21	-	26780180	HT29	viability (Avana library 4 designs)	GGTTGCTGTTTCATGACAGGGGG	ITSN1	ENSG00000205726	0.753568169490632	[]	[]	3	hSpCas9	negative selection	3433684
33735174	33735197	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	3.13151701779798	[]	[]	5	hSpCas9	negative selection	3520409
33750178	33750201	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTTGCTCCAGTGCCAATGGG	ITSN1	ENSG00000205726	4.21727769672929	[]	[]	7	hSpCas9	negative selection	3520410
33735153	33735176	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTGCTGTTTCATGACAGGGGG	ITSN1	ENSG00000205726	3.70041223143963	[]	[]	6	hSpCas9	negative selection	3520411
33751834	33751857	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTTAGTAGATCTGGTCCAGGG	ITSN1	ENSG00000205726	1.25154912491569	[]	[]	1	hSpCas9	negative selection	3520412
33750298	33750321	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	3.02483391222386	[]	[]	4	hSpCas9	negative selection	3520413
33772247	33772270	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGCAACTGGAAAAGCAGCGG	ITSN1	ENSG00000205726	-2.61547157646011	[]	[]	-3	hSpCas9	negative selection	3520414
33735174	33735197	21	-	26780180	A375	viability (Avana lentiGuide)	GGTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	2.33028434591265	[]	[]	2	hSpCas9	negative selection	3629068
33750178	33750201	21	+	26780180	A375	viability (Avana lentiGuide)	GCTGTTGCTCCAGTGCCAATGGG	ITSN1	ENSG00000205726	-3.50436087705896	[]	[]	-6	hSpCas9	negative selection	3629069
33735153	33735176	21	-	26780180	A375	viability (Avana lentiGuide)	GGTTGCTGTTTCATGACAGGGGG	ITSN1	ENSG00000205726	-0.980183177319201	[]	[]	-1	hSpCas9	negative selection	3629070
33751834	33751857	21	+	26780180	A375	viability (Avana lentiGuide)	CCTTTAGTAGATCTGGTCCAGGG	ITSN1	ENSG00000205726	-4.65010189527562	[]	[]	-7	hSpCas9	negative selection	3629071
33750298	33750321	21	-	26780180	A375	viability (Avana lentiGuide)	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	5.80811251656287	[]	[]	5	hSpCas9	negative selection	3629072
33772247	33772270	21	+	26780180	A375	viability (Avana lentiGuide)	AGAAGCAACTGGAAAAGCAGCGG	ITSN1	ENSG00000205726	-4.38171297022125	[]	[]	-7	hSpCas9	negative selection	3629073
33735174	33735197	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	0.026507235974516957	[5]	[5,5]	0	hSpCas9	positive selection	3737727
33750178	33750201	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTTGCTCCAGTGCCAATGGG	ITSN1	ENSG00000205726	0.13036221638106124	[4]	[4,4]	3	hSpCas9	positive selection	3737728
33735153	33735176	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTGCTGTTTCATGACAGGGGG	ITSN1	ENSG00000205726	0.18015159428379937	[6]	[7,6]	5	hSpCas9	positive selection	3737729
33751834	33751857	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTTAGTAGATCTGGTCCAGGG	ITSN1	ENSG00000205726	0.08439549064555368	[6]	[6,6]	2	hSpCas9	positive selection	3737730
33750298	33750321	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.38222188795242173	[4]	[5,5]	9	hSpCas9	positive selection	3737731
33772247	33772270	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGCAACTGGAAAAGCAGCGG	ITSN1	ENSG00000205726	-0.42153421784028205	[4]	[3,2]	-6	hSpCas9	positive selection	3737732
33735174	33735197	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	0.13756153419764044	[6]	[5,5]	3	hSpCas9	positive selection	3846334
33750178	33750201	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTTGCTCCAGTGCCAATGGG	ITSN1	ENSG00000205726	-0.17757792926976848	[6]	[3,4]	-2	hSpCas9	positive selection	3846335
33735153	33735176	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTGCTGTTTCATGACAGGGGG	ITSN1	ENSG00000205726	0.19184793562168306	[7]	[7,6]	5	hSpCas9	positive selection	3846336
33751834	33751857	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTTAGTAGATCTGGTCCAGGG	ITSN1	ENSG00000205726	0.32880687028079536	[6]	[6,7]	8	hSpCas9	positive selection	3846337
33750298	33750321	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.26685326952566196	[5]	[6,5]	7	hSpCas9	positive selection	3846338
33772247	33772270	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGCAACTGGAAAAGCAGCGG	ITSN1	ENSG00000205726	0.29287230381284274	[4]	[4,5]	7	hSpCas9	positive selection	3846339
33751885	33751908	21	+	26780180	A375	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.364267644682319	[]	[]	0	hSpCas9	negative selection	3952364
33721237	33721260	21	+	26780180	A375	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	1.25206811522077	[]	[]	6	hSpCas9	negative selection	3952365
33721249	33721272	21	-	26780180	A375	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	0.875973110552508	[]	[]	3	hSpCas9	negative selection	3952366
33721196	33721219	21	-	26780180	A375	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.206959322179756	[]	[]	0	hSpCas9	negative selection	3952367
33722632	33722655	21	-	26780180	A375	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.87010734756105	[]	[]	3	hSpCas9	negative selection	3952368
33751851	33751874	21	-	26780180	A375	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	1.27209635453118	[]	[]	7	hSpCas9	negative selection	3952369
33751885	33751908	21	+	26780180	HT29	viability (GeCKOv2 library)	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	1.02289908344843	[]	[]	4	hSpCas9	negative selection	4060330
33721237	33721260	21	+	26780180	HT29	viability (GeCKOv2 library)	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	1.50072885741071	[]	[]	7	hSpCas9	negative selection	4060331
33721249	33721272	21	-	26780180	HT29	viability (GeCKOv2 library)	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	1.0192984581978	[]	[]	4	hSpCas9	negative selection	4060332
33721196	33721219	21	-	26780180	HT29	viability (GeCKOv2 library)	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.444459630971192	[]	[]	1	hSpCas9	negative selection	4060333
33722632	33722655	21	-	26780180	HT29	viability (GeCKOv2 library)	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	1.213208587564	[]	[]	6	hSpCas9	negative selection	4060334
33751851	33751874	21	-	26780180	HT29	viability (GeCKOv2 library)	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	1.47369043448034	[]	[]	7	hSpCas9	negative selection	4060335
33722630	33722653	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACCTGTTTTAGCACAGATATGG	ITSN1	ENSG00000205726	0.13544610693109252	[4]	[2,3]	3	hSpCas9	positive selection	4145641
33721249	33721272	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.07667165936939335	[4]	[2,2]	-2	hSpCas9	positive selection	4145643
33721196	33721219	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.2072925123601322	[4]	[3,3]	5	hSpCas9	positive selection	4145644
33722632	33722655	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.19147863731736237	[2]	[1,2]	5	hSpCas9	positive selection	4145645
33722630	33722653	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACCTGTTTTAGCACAGATATGG	ITSN1	ENSG00000205726	0.4490216610300398	[3]	[3,4,3,0]	3	hSpCas9	positive selection	4209663
33721249	33721272	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	0.6880312766318624	[4]	[3,3,4,2]	4	hSpCas9	positive selection	4209665
33721196	33721219	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	1.0882381695269991	[4]	[5,3,3,4]	7	hSpCas9	positive selection	4209666
33722632	33722655	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.8315453223292795	[4]	[2,4,0,4]	5	hSpCas9	positive selection	4209667
33751851	33751874	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	-0.06454657699302813	[3]	[3,1]	-1	hSpCas9	positive selection	4277550
33721196	33721219	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.19903354329658615	[3]	[4,1]	4	hSpCas9	positive selection	4277551
33751885	33751908	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.17208402519408061	[3]	[3,2]	3	hSpCas9	positive selection	4277552
33721249	33721272	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	0.23772402910594637	[3]	[3,3]	5	hSpCas9	positive selection	4341805
33722632	33722655	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.2138439588105119	[2]	[2,0]	-4	hSpCas9	positive selection	4341806
33721237	33721260	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	-0.03998818187390586	[3]	[3,1]	-1	hSpCas9	positive selection	4341807
33772087	33772109	21	+	27760321	OCIAML3	viability	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	0.1698152194939362	[643,551]	[326,781]	2	hSpCas9	negative selection	4410711
33774755	33774777	21	+	27760321	OCIAML3	viability	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	0.8939123407961014	[562,409]	[671,736]	9	hSpCas9	negative selection	4410712
33775012	33775034	21	+	27760321	OCIAML3	viability	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.9444921487473443	[393,332]	[443,676]	9	hSpCas9	negative selection	4410713
33735174	33735196	21	-	27760321	OCIAML3	viability	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	-0.07520213701936074	[193,173]	[135,136]	-1	hSpCas9	negative selection	4410714
33750158	33750180	21	-	27760321	OCIAML3	viability	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	0.12264693610526545	[676,621]	[591,501]	1	hSpCas9	negative selection	4410715
33772087	33772109	21	+	27760321	OCIAML2	viability	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	0.1735402593481129	[643,551]	[489,614]	2	hSpCas9	negative selection	4494174
33774755	33774777	21	+	27760321	OCIAML2	viability	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	-0.02931185518599559	[562,409]	[349,423]	0	hSpCas9	negative selection	4494175
33775012	33775034	21	+	27760321	OCIAML2	viability	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.04214884432465579	[393,332]	[305,295]	0	hSpCas9	negative selection	4494176
33735174	33735196	21	-	27760321	OCIAML2	viability	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	-0.6310454371146115	[193,173]	[95,95]	-6	hSpCas9	negative selection	4494177
33750158	33750180	21	-	27760321	OCIAML2	viability	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-0.0045916344305340084	[676,621]	[407,675]	0	hSpCas9	negative selection	4494178
33772087	33772109	21	+	27760321	MV411	viability	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	0.4009547606984123	[643,551]	[363,752]	3	hSpCas9	negative selection	4577637
33774755	33774777	21	+	27760321	MV411	viability	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	-0.003134964328312312	[562,409]	[150,566]	0	hSpCas9	negative selection	4577638
33775012	33775034	21	+	27760321	MV411	viability	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.4219899846873941	[393,332]	[101,647]	3	hSpCas9	negative selection	4577639
33735174	33735196	21	-	27760321	MV411	viability	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	-1.0357746002019468	[193,173]	[3,141]	-6	hSpCas9	negative selection	4577640
33750158	33750180	21	-	27760321	MV411	viability	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-0.13355888470113525	[676,621]	[189,691]	-1	hSpCas9	negative selection	4577641
33772087	33772109	21	+	27760321	HL60	viability	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	0.5992532367385002	[643,551]	[531,955]	7	hSpCas9	negative selection	4661100
33774755	33774777	21	+	27760321	HL60	viability	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	0.15191991709072214	[562,409]	[330,549]	1	hSpCas9	negative selection	4661101
33775012	33775034	21	+	27760321	HL60	viability	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	-0.7946536572124088	[393,332]	[155,185]	-7	hSpCas9	negative selection	4661102
33735174	33735196	21	-	27760321	HL60	viability	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	-0.6888846292209958	[193,173]	[113,70]	-6	hSpCas9	negative selection	4661103
33750158	33750180	21	-	27760321	HL60	viability	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-1.066843351448901	[676,621]	[243,262]	-8	hSpCas9	negative selection	4661104
33772087	33772109	21	+	27760321	HT1080	viability	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	-2.0777359172933743	[551,430]	[64,25]	-6	hSpCas9	negative selection	4744563
33774755	33774777	21	+	27760321	HT1080	viability	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	-0.8773605975081924	[409,319]	[113,40]	-4	hSpCas9	negative selection	4744564
33775012	33775034	21	+	27760321	HT1080	viability	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	-0.7593557526767645	[332,259]	[22,120]	-3	hSpCas9	negative selection	4744565
33735174	33735196	21	-	27760321	HT1080	viability	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	1.0593166295974132	[173,135]	[79,181]	6	hSpCas9	negative selection	4744566
33750158	33750180	21	-	27760321	HT1080	viability	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	0.036086229437772066	[621,485]	[179,276]	0	hSpCas9	negative selection	4744567
33772087	33772109	21	+	27760321	HT29	viability after 7 days	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	0.09157199002006189	[551,430]	[751,785,497]	1	hSpCas9	negative selection	4828026
33774755	33774777	21	+	27760321	HT29	viability after 7 days	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	0.428953048142877	[409,319]	[645,667,583]	6	hSpCas9	negative selection	4828027
33775012	33775034	21	+	27760321	HT29	viability after 7 days	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	-0.26261374272720284	[332,259]	[256,330,354]	-4	hSpCas9	negative selection	4828028
33735174	33735196	21	-	27760321	HT29	viability after 7 days	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	-0.5057106082385616	[173,135]	[122,172,122]	-6	hSpCas9	negative selection	4828029
33750158	33750180	21	-	27760321	HT29	viability after 7 days	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-0.6550700647677616	[621,485]	[628,502,255]	-7	hSpCas9	negative selection	4828030
33772087	33772109	21	+	27760321	HT29	viability after 25 days	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	-0.14718537948133975	[551,430]	[538,428,555]	-1	hSpCas9	negative selection	4911489
33774755	33774777	21	+	27760321	HT29	viability after 25 days	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	0.42269529771848885	[409,319]	[479,491,726]	4	hSpCas9	negative selection	4911490
33775012	33775034	21	+	27760321	HT29	viability after 25 days	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.27172864551629167	[332,259]	[418,285,533]	3	hSpCas9	negative selection	4911491
33735174	33735196	21	-	27760321	HT29	viability after 25 days	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	0.621136524421028	[173,135]	[317,224,270]	7	hSpCas9	negative selection	4911492
33750158	33750180	21	-	27760321	HT29	viability after 25 days	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-0.28323297812971665	[621,485]	[589,356,618]	-3	hSpCas9	negative selection	4911493
33772087	33772109	21	+	27760321	HT29	viability after 22 days	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	0.34699715525158004	[551,430]	[926,470,764]	3	hSpCas9	negative selection	4994952
33774755	33774777	21	+	27760321	HT29	viability after 22 days	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	0.6514607308771013	[409,319]	[679,633,673]	7	hSpCas9	negative selection	4994953
33775012	33775034	21	+	27760321	HT29	viability after 22 days	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.06586340740603305	[332,259]	[205,356,518]	0	hSpCas9	negative selection	4994954
33735174	33735196	21	-	27760321	HT29	viability after 22 days	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	-0.16825355565757705	[173,135]	[113,169,195]	-2	hSpCas9	negative selection	4994955
33750158	33750180	21	-	27760321	HT29	viability after 22 days	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-0.5837196317903498	[621,485]	[449,452,377]	-5	hSpCas9	negative selection	4994956
33772087	33772109	21	+	27760321	HT29	viability after 19 days	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	0.3138890142079743	[551,430]	[752,609,736]	3	hSpCas9	negative selection	5078415
33774755	33774777	21	+	27760321	HT29	viability after 19 days	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	0.5046302900385461	[409,319]	[623,598,557]	5	hSpCas9	negative selection	5078416
33775012	33775034	21	+	27760321	HT29	viability after 19 days	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.5512352856641692	[332,259]	[498,665,331]	5	hSpCas9	negative selection	5078417
33735174	33735196	21	-	27760321	HT29	viability after 19 days	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	0.10380638646300011	[173,135]	[137,212,213]	0	hSpCas9	negative selection	5078418
33750158	33750180	21	-	27760321	HT29	viability after 19 days	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-0.29665754253714277	[621,485]	[482,522,536]	-3	hSpCas9	negative selection	5078419
33772087	33772109	21	+	27760321	HT29	viability after 16 days	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	-0.17461814636858114	[551,430]	[603,433,435]	-2	hSpCas9	negative selection	5161878
33774755	33774777	21	+	27760321	HT29	viability after 16 days	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	0.41683523363237723	[409,319]	[282,607,717]	5	hSpCas9	negative selection	5161879
33775012	33775034	21	+	27760321	HT29	viability after 16 days	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.40908754423682503	[332,259]	[451,420,449]	4	hSpCas9	negative selection	5161880
33735174	33735196	21	-	27760321	HT29	viability after 16 days	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	-0.1804349213288723	[173,135]	[294,95,82]	-2	hSpCas9	negative selection	5161881
33750158	33750180	21	-	27760321	HT29	viability after 16 days	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-0.47445542685804587	[621,485]	[546,287,516]	-5	hSpCas9	negative selection	5161882
33772087	33772109	21	+	27760321	HT29	viability after 13 days	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	0.11530958912000511	[551,430]	[708,378,755]	1	hSpCas9	negative selection	5245341
33774755	33774777	21	+	27760321	HT29	viability after 13 days	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	0.5918687174900569	[409,319]	[520,588,794]	7	hSpCas9	negative selection	5245342
33775012	33775034	21	+	27760321	HT29	viability after 13 days	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.6705095139314703	[332,259]	[738,424,481]	8	hSpCas9	negative selection	5245343
33735174	33735196	21	-	27760321	HT29	viability after 13 days	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	0.3978554675890108	[173,135]	[289,291,134]	5	hSpCas9	negative selection	5245344
33750158	33750180	21	-	27760321	HT29	viability after 13 days	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-0.4435993603360864	[621,485]	[431,464,517]	-5	hSpCas9	negative selection	5245345
33772087	33772109	21	+	27760321	HT29	viability after 10 days	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	-0.24545488493102924	[551,430]	[452,507,589]	-3	hSpCas9	negative selection	5328804
33774755	33774777	21	+	27760321	HT29	viability after 10 days	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	0.24229357796570933	[409,319]	[534,578,504]	3	hSpCas9	negative selection	5328805
33775012	33775034	21	+	27760321	HT29	viability after 10 days	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.18609924727551477	[332,259]	[389,485,389]	2	hSpCas9	negative selection	5328806
33735174	33735196	21	-	27760321	HT29	viability after 10 days	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	-1.2219757717945483	[173,135]	[55,76,114]	-8	hSpCas9	negative selection	5328807
33750158	33750180	21	-	27760321	HT29	viability after 10 days	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-0.44060901631854976	[621,485]	[260,680,589]	-5	hSpCas9	negative selection	5328808
33772087	33772109	21	+	27760321	MOLM13	viability	AACTTTGAACGTGGCAACCTGG	ITSN1	ENSG00000205726	0.39451938047631785	[643,551]	[392,483]	2	hSpCas9	negative selection	5412267
33774755	33774777	21	+	27760321	MOLM13	viability	ACGACAACTTGAGTGGGAACGG	ITSN1	ENSG00000205726	0.4209944381034547	[562,409]	[525,225]	3	hSpCas9	negative selection	5412268
33775012	33775034	21	+	27760321	MOLM13	viability	ATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	1.159171574903187	[393,332]	[511,408]	7	hSpCas9	negative selection	5412269
33735174	33735196	21	-	27760321	MOLM13	viability	GTGCGCTAGAAATAGCAACTGG	ITSN1	ENSG00000205726	-0.14951161139031277	[193,173]	[86,98]	-1	hSpCas9	negative selection	5412270
33750158	33750180	21	-	27760321	MOLM13	viability	GCTGTAAGCGGTGGCATGCTGG	ITSN1	ENSG00000205726	-0.9385473787312972	[676,621]	[262,129]	-5	hSpCas9	negative selection	5412271
33642584	33642607	21	+	27661255	K562	viability	GGGCTCCGGGACGGACAGAGAGG	ITSN1	ENSG00000205726	-0.011759692871823768	[628,704]	[555,502]	0	dCas9-KRAB	negative selection	5487512
33642577	33642600	21	-	27661255	K562	viability	GTCCGTCCCGGAGCCCGCTCGGG	ITSN1	ENSG00000205726	0.04712668839163747	[63,54]	[45,51]	1	dCas9-KRAB	negative selection	5487513
33643076	33643099	21	-	27661255	K562	viability	GAGGGCAGCGAGGTCAGCCCGGG	ITSN1	ENSG00000205726	0.13747256550098513	[1017,1093]	[1079,795]	5	dCas9-KRAB	negative selection	5487514
33751851	33751874	21	-	27260156	BXPC3	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.14426906264805783	[766]	[804,923,949,864]	3	hSpCas9	negative selection	5550010
33721196	33721219	21	-	27260156	BXPC3	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.5715544807954385	[532]	[786,823,876,823]	9	hSpCas9	negative selection	5550011
33751885	33751908	21	+	27260156	BXPC3	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.2315445031633897	[719]	[808,776,1128,825]	5	hSpCas9	negative selection	5550012
33721249	33721272	21	-	27260156	BXPC3	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.13713137529286956	[967]	[826,980,936,938]	-3	hSpCas9	negative selection	5614265
33722632	33722655	21	-	27260156	BXPC3	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.05544239400114501	[403]	[419,360,518,463]	1	hSpCas9	negative selection	5614266
33721237	33721260	21	+	27260156	BXPC3	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	-0.10872041058243426	[476]	[368,400,464,648]	-3	hSpCas9	negative selection	5614267
33751851	33751874	21	-	27260156	A673	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.0679867369506918	[766]	[988,801,1011,1068]	1	hSpCas9	negative selection	5671261
33721196	33721219	21	-	27260156	A673	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.7181125236731916	[532]	[1077,906,967,1275]	9	hSpCas9	negative selection	5671262
33751885	33751908	21	+	27260156	A673	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.23410296356817495	[719]	[1063,1056,909,1040]	5	hSpCas9	negative selection	5671263
33721249	33721272	21	-	27260156	A673	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.08279350661577789	[967]	[1293,989,1014,1115]	-2	hSpCas9	negative selection	5735516
33722632	33722655	21	-	27260156	A673	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.034018385740080787	[403]	[463,509,464,451]	-1	hSpCas9	negative selection	5735517
33721237	33721260	21	+	27260156	A673	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.015344343649958292	[476]	[622,487,533,682]	0	hSpCas9	negative selection	5735518
33751851	33751874	21	-	27260156	A375	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.2292330351789139	[766]	[857,1226,995,1128]	3	hSpCas9	negative selection	5792512
33721196	33721219	21	-	27260156	A375	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.9036038287246078	[532]	[952,1407,1075,1239]	9	hSpCas9	negative selection	5792513
33751885	33751908	21	+	27260156	A375	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.7655258777650749	[719]	[1375,1783,1460,1171]	9	hSpCas9	negative selection	5792514
33721249	33721272	21	-	27260156	A375	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.3445575294471026	[967]	[951,970,951,715]	-5	hSpCas9	negative selection	5856767
33722632	33722655	21	-	27260156	A375	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.35221184128519445	[403]	[607,613,540,640]	5	hSpCas9	negative selection	5856768
33721237	33721260	21	+	27260156	A375	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.3761365287546859	[476]	[612,771,902,619]	5	hSpCas9	negative selection	5856769
33751851	33751874	21	-	27260156	COLO741	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.09595543637848136	[766]	[1194,1103,866]	2	hSpCas9	negative selection	5913763
33721196	33721219	21	-	27260156	COLO741	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.5542421663789698	[532]	[1136,1023,858]	9	hSpCas9	negative selection	5913764
33751885	33751908	21	+	27260156	COLO741	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.2757274635786523	[719]	[1264,1193,907]	6	hSpCas9	negative selection	5913765
33721249	33721272	21	-	27260156	COLO741	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.02682331556967288	[967]	[1250,1226,1167]	0	hSpCas9	negative selection	5978018
33722632	33722655	21	-	27260156	COLO741	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.1647844114871182	[403]	[668,631,450]	3	hSpCas9	negative selection	5978019
33721237	33721260	21	+	27260156	COLO741	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.24268348044400778	[476]	[750,758,658]	5	hSpCas9	negative selection	5978020
33751851	33751874	21	-	27260156	CAL120	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	-0.07165395340379033	[766]	[926,1000,800]	-1	hSpCas9	negative selection	6035014
33721196	33721219	21	-	27260156	CAL120	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	1.119303212819302	[532]	[1792,1531,1056]	9	hSpCas9	negative selection	6035015
33751885	33751908	21	+	27260156	CAL120	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.3747429441097314	[719]	[1483,935,1113]	5	hSpCas9	negative selection	6035016
33721249	33721272	21	-	27260156	CAL120	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	0.01821044593493415	[967]	[1140,993,1506]	0	hSpCas9	negative selection	6099269
33722632	33722655	21	-	27260156	CAL120	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.22525065524021384	[403]	[519,609,621]	3	hSpCas9	negative selection	6099270
33721237	33721260	21	+	27260156	CAL120	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	-0.09232895440663348	[476]	[372,575,690]	-1	hSpCas9	negative selection	6099271
33751851	33751874	21	-	27260156	CADOES1	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.030376218855614034	[766]	[619,841,816,631]	0	hSpCas9	negative selection	6156265
33721196	33721219	21	-	27260156	CADOES1	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.8184091576328498	[532]	[666,1035,858,937]	9	hSpCas9	negative selection	6156266
33751885	33751908	21	+	27260156	CADOES1	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.4347716348629993	[719]	[714,874,997,1037]	7	hSpCas9	negative selection	6156267
33721249	33721272	21	-	27260156	CADOES1	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.1941947207017901	[967]	[777,596,863,912]	-3	hSpCas9	negative selection	6220520
33722632	33722655	21	-	27260156	CADOES1	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.28214163150939575	[403]	[509,463,434,416]	5	hSpCas9	negative selection	6220521
33721237	33721260	21	+	27260156	CADOES1	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.18768015798286547	[476]	[503,609,486,416]	3	hSpCas9	negative selection	6220522
33751851	33751874	21	-	27260156	EWS502	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.3678133963783441	[766]	[705,852,1283,1425]	6	hSpCas9	negative selection	6277516
33721196	33721219	21	-	27260156	EWS502	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.652705457229455	[532]	[686,831,1028,1037]	9	hSpCas9	negative selection	6277517
33751885	33751908	21	+	27260156	EWS502	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.5389177052958798	[719]	[902,1110,1196,1252]	8	hSpCas9	negative selection	6277518
33721249	33721272	21	-	27260156	EWS502	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	0.010758133723660412	[967]	[993,942,1008,1201]	0	hSpCas9	negative selection	6341771
33722632	33722655	21	-	27260156	EWS502	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.15955911792728347	[403]	[415,322,322,472]	-3	hSpCas9	negative selection	6341772
33721237	33721260	21	+	27260156	EWS502	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.15233821895976318	[476]	[619,403,521,706]	2	hSpCas9	negative selection	6341773
33751851	33751874	21	-	27260156	EW8	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.10672150169010763	[766]	[686,710,540,759]	2	hSpCas9	negative selection	6398767
33721196	33721219	21	-	27260156	EW8	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.7155957882687849	[532]	[860,673,601,732]	9	hSpCas9	negative selection	6398768
33751885	33751908	21	+	27260156	EW8	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.34144093851221924	[719]	[897,713,629,748]	6	hSpCas9	negative selection	6398769
33721249	33721272	21	-	27260156	EW8	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.1100424990115747	[967]	[882,774,518,780]	-2	hSpCas9	negative selection	6463022
33722632	33722655	21	-	27260156	EW8	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.2577144844969572	[403]	[271,313,271,236]	-5	hSpCas9	negative selection	6463023
33721237	33721260	21	+	27260156	EW8	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.0950354750953426	[476]	[340,513,406,381]	1	hSpCas9	negative selection	6463024
33751851	33751874	21	-	27260156	CORL105	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.17277754094080855	[766]	[1012,898,1111,1041]	3	hSpCas9	negative selection	6520018
33721196	33721219	21	-	27260156	CORL105	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.8519368885279974	[532]	[986,1023,1602,962]	9	hSpCas9	negative selection	6520019
33751885	33751908	21	+	27260156	CORL105	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.43991656951801783	[719]	[1039,933,1427,1215]	7	hSpCas9	negative selection	6520020
33721249	33721272	21	-	27260156	CORL105	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.20408313867312333	[967]	[897,940,1158,961]	-4	hSpCas9	negative selection	6584273
33722632	33722655	21	-	27260156	CORL105	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.12561356927195907	[403]	[564,359,721,453]	2	hSpCas9	negative selection	6584274
33721237	33721260	21	+	27260156	CORL105	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	-0.10566655832835041	[476]	[578,559,503,431]	-2	hSpCas9	negative selection	6584275
33751851	33751874	21	-	27260156	HS294T	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	-0.14958949928418142	[766]	[255,210,274,341]	-2	hSpCas9	negative selection	6641269
33721196	33721219	21	-	27260156	HS294T	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	1.029592595817094	[532]	[315,493,363,533]	9	hSpCas9	negative selection	6641270
33751885	33751908	21	+	27260156	HS294T	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	1.0077800026430852	[719]	[610,558,443,629]	9	hSpCas9	negative selection	6641271
33721249	33721272	21	-	27260156	HS294T	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.09971436268524936	[967]	[241,393,418,349]	-1	hSpCas9	negative selection	6705524
33722632	33722655	21	-	27260156	HS294T	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.5278790524180742	[403]	[299,136,122,357]	7	hSpCas9	negative selection	6705525
33721237	33721260	21	+	27260156	HS294T	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	-0.41726117712063004	[476]	[141,154,125,125]	-5	hSpCas9	negative selection	6705526
33751851	33751874	21	-	27260156	HCC44	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	-0.03642484819029701	[766]	[889,748,854,899]	0	hSpCas9	negative selection	6762520
33721196	33721219	21	-	27260156	HCC44	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.8375480034554161	[532]	[1087,1138,870,1155]	9	hSpCas9	negative selection	6762521
33751885	33751908	21	+	27260156	HCC44	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.21936313523097606	[719]	[1102,761,1193,812]	3	hSpCas9	negative selection	6762522
33721249	33721272	21	-	27260156	HCC44	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.3867849508764467	[967]	[975,566,1022,858]	-6	hSpCas9	negative selection	6826775
33722632	33722655	21	-	27260156	HCC44	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.12478335787732323	[403]	[448,289,874,465]	2	hSpCas9	negative selection	6826776
33721237	33721260	21	+	27260156	HCC44	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	-0.1549246091389112	[476]	[560,520,490,367]	-3	hSpCas9	negative selection	6826777
33751851	33751874	21	-	27260156	G402	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	-0.014510143985273616	[766]	[1293,855,685,915]	0	hSpCas9	negative selection	6883771
33721196	33721219	21	-	27260156	G402	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.7485178050222521	[532]	[1811,1193,691,792]	8	hSpCas9	negative selection	6883772
33751885	33751908	21	+	27260156	G402	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.5802446647665658	[719]	[1760,1405,1220,948]	7	hSpCas9	negative selection	6883773
33721249	33721272	21	-	27260156	G402	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.29161979850716624	[967]	[1593,613,803,916]	-4	hSpCas9	negative selection	6948026
33722632	33722655	21	-	27260156	G402	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.3214844288671658	[403]	[396,515,593,902]	4	hSpCas9	negative selection	6948027
33721237	33721260	21	+	27260156	G402	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.47529520523312785	[476]	[649,950,729,883]	6	hSpCas9	negative selection	6948028
33751851	33751874	21	-	27260156	L33	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.10767682201205864	[766]	[823,364,507,782]	2	hSpCas9	negative selection	7005022
33721196	33721219	21	-	27260156	L33	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.2888692409259237	[532]	[630,238,440,688]	6	hSpCas9	negative selection	7005023
33751885	33751908	21	+	27260156	L33	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.20852630006351502	[719]	[783,346,590,758]	4	hSpCas9	negative selection	7005024
33721249	33721272	21	-	27260156	L33	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	0.030436600105138156	[967]	[1075,420,576,930]	0	hSpCas9	negative selection	7069277
33722632	33722655	21	-	27260156	L33	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.03744255930761095	[403]	[361,165,239,425]	-1	hSpCas9	negative selection	7069278
33721237	33721260	21	+	27260156	L33	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	-0.12155427829692056	[476]	[557,163,140,565]	-3	hSpCas9	negative selection	7069279
33751851	33751874	21	-	27260156	K562	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.06977049866345442	[766]	[616,605,725,872]	0	hSpCas9	negative selection	7126273
33721196	33721219	21	-	27260156	K562	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.99175482902896	[532]	[1258,865,888,784]	9	hSpCas9	negative selection	7126274
33751885	33751908	21	+	27260156	K562	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.4199059006880679	[719]	[821,1071,832,713]	5	hSpCas9	negative selection	7126275
33721249	33721272	21	-	27260156	K562	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.6162460604074105	[967]	[749,525,520,466]	-6	hSpCas9	negative selection	7190528
33722632	33722655	21	-	27260156	K562	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.3808497924279628	[403]	[298,274,232,292]	-5	hSpCas9	negative selection	7190529
33721237	33721260	21	+	27260156	K562	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.3509569049215513	[476]	[641,625,464,447]	4	hSpCas9	negative selection	7190530
33751851	33751874	21	-	27260156	HT29	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.21907135250054643	[766]	[1224,996,1115,1007]	4	hSpCas9	negative selection	7247524
33721196	33721219	21	-	27260156	HT29	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.6597995547756899	[532]	[1198,916,1118,874]	9	hSpCas9	negative selection	7247525
33751885	33751908	21	+	27260156	HT29	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.33139123480391786	[719]	[1173,1169,1039,1032]	6	hSpCas9	negative selection	7247526
33721249	33721272	21	-	27260156	HT29	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.18010024199641672	[967]	[991,1052,1118,986]	-4	hSpCas9	negative selection	7311779
33722632	33722655	21	-	27260156	HT29	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.23203495132414095	[403]	[390,419,459,398]	-4	hSpCas9	negative selection	7311780
33721237	33721260	21	+	27260156	HT29	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.14114294073909084	[476]	[703,815,411,640]	2	hSpCas9	negative selection	7311781
33751851	33751874	21	-	27260156	MHHES1	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.3548375859311361	[766]	[1297,1037,1105,993]	6	hSpCas9	negative selection	7368775
33721196	33721219	21	-	27260156	MHHES1	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.8946072369306375	[532]	[1416,1417,973,775]	9	hSpCas9	negative selection	7368776
33751885	33751908	21	+	27260156	MHHES1	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.20047134890935236	[719]	[1382,813,819,768]	3	hSpCas9	negative selection	7368777
33721249	33721272	21	-	27260156	MHHES1	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.3671101851376428	[967]	[768,822,966,801]	-6	hSpCas9	negative selection	7433030
33722632	33722655	21	-	27260156	MHHES1	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.10890475956053017	[403]	[622,531,595,272]	2	hSpCas9	negative selection	7433031
33721237	33721260	21	+	27260156	MHHES1	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.2605593497427466	[476]	[1087,651,550,383]	5	hSpCas9	negative selection	7433032
33751851	33751874	21	-	27260156	MEWO	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.27224716380658043	[766]	[969,796,852]	6	hSpCas9	negative selection	7490026
33721196	33721219	21	-	27260156	MEWO	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.6370139027772086	[532]	[909,626,815]	9	hSpCas9	negative selection	7490027
33751885	33751908	21	+	27260156	MEWO	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.18583333766028698	[719]	[820,779,707]	4	hSpCas9	negative selection	7490028
33721249	33721272	21	-	27260156	MEWO	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.4170886533324395	[967]	[789,730,534]	-7	hSpCas9	negative selection	7554281
33722632	33722655	21	-	27260156	MEWO	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.09899431940447197	[403]	[473,353,399]	2	hSpCas9	negative selection	7554282
33721237	33721260	21	+	27260156	MEWO	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	-0.08036751981541546	[476]	[430,397,438]	-2	hSpCas9	negative selection	7554283
33751851	33751874	21	-	27260156	LNCAPCLONEFGC	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.10593148285358578	[766]	[672,537,971,855]	1	hSpCas9	negative selection	7611277
33721196	33721219	21	-	27260156	LNCAPCLONEFGC	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.8739755054599461	[532]	[1008,801,918,816]	9	hSpCas9	negative selection	7611278
33751885	33751908	21	+	27260156	LNCAPCLONEFGC	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.5518750865665509	[719]	[936,876,1201,849]	8	hSpCas9	negative selection	7611279
33721249	33721272	21	-	27260156	LNCAPCLONEFGC	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.5185361709493156	[967]	[517,618,817,524]	-7	hSpCas9	negative selection	7675532
33722632	33722655	21	-	27260156	LNCAPCLONEFGC	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.020571847703450552	[403]	[266,395,424,404]	0	hSpCas9	negative selection	7675533
33721237	33721260	21	+	27260156	LNCAPCLONEFGC	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.02107911005594651	[476]	[525,394,507,335]	0	hSpCas9	negative selection	7675534
33751851	33751874	21	-	27260156	PANC0327	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.25880304902639506	[766]	[797,870,819,762]	4	hSpCas9	negative selection	7732528
33721196	33721219	21	-	27260156	PANC0327	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.7951810133873727	[532]	[1068,710,900,639]	9	hSpCas9	negative selection	7732529
33751885	33751908	21	+	27260156	PANC0327	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.7178622240131798	[719]	[1338,805,733,1382]	9	hSpCas9	negative selection	7732530
33721249	33721272	21	-	27260156	PANC0327	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.2834855300580873	[967]	[959,817,559,493]	-4	hSpCas9	negative selection	7796783
33722632	33722655	21	-	27260156	PANC0327	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.1060729263832326	[403]	[345,284,374,334]	-1	hSpCas9	negative selection	7796784
33721237	33721260	21	+	27260156	PANC0327	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.284539003638213	[476]	[588,840,269,327]	4	hSpCas9	negative selection	7796785
33751851	33751874	21	-	27260156	NCIH2009	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.2599532542774844	[766]	[1794,1149,1005]	3	hSpCas9	negative selection	7853779
33721196	33721219	21	-	27260156	NCIH2009	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.6857044950584228	[532]	[1171,1269,1142]	8	hSpCas9	negative selection	7853780
33751885	33751908	21	+	27260156	NCIH2009	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.477512680538585	[719]	[1961,1095,1257]	6	hSpCas9	negative selection	7853781
33721249	33721272	21	-	27260156	NCIH2009	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.21673093881637517	[967]	[1474,1104,971]	-3	hSpCas9	negative selection	7918034
33722632	33722655	21	-	27260156	NCIH2009	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.0678326971571161	[403]	[726,515,558]	0	hSpCas9	negative selection	7918035
33721237	33721260	21	+	27260156	NCIH2009	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.2593256352225348	[476]	[788,850,748]	3	hSpCas9	negative selection	7918036
33751851	33751874	21	-	27260156	NCIH1373	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	-0.06174957794123803	[766]	[563,586,1050,284]	0	hSpCas9	negative selection	7975030
33721196	33721219	21	-	27260156	NCIH1373	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	1.121773271991222	[532]	[1366,825,1747,342]	9	hSpCas9	negative selection	7975031
33751885	33751908	21	+	27260156	NCIH1373	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.9529310764608518	[719]	[1422,1022,1860,522]	8	hSpCas9	negative selection	7975032
33721249	33721272	21	-	27260156	NCIH1373	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.5187011224295008	[967]	[956,770,429,239]	-5	hSpCas9	negative selection	8039285
33722632	33722655	21	-	27260156	NCIH1373	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.10728903500200992	[403]	[383,665,496,93]	1	hSpCas9	negative selection	8039286
33721237	33721260	21	+	27260156	NCIH1373	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.5169212120431909	[476]	[889,716,856,158]	5	hSpCas9	negative selection	8039287
33751851	33751874	21	-	27260156	PATU8902	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.2426318755567417	[766]	[1140,1123,1659,984]	2	hSpCas9	negative selection	8096281
33721196	33721219	21	-	27260156	PATU8902	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	1.3715130027462006	[532]	[2329,1418,1949,1957]	9	hSpCas9	negative selection	8096282
33751885	33751908	21	+	27260156	PATU8902	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.8910484292011978	[719]	[1551,1507,1456,3170]	8	hSpCas9	negative selection	8096283
33721249	33721272	21	-	27260156	PATU8902	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.21982909056347788	[967]	[810,1579,953,1358]	-2	hSpCas9	negative selection	8160536
33722632	33722655	21	-	27260156	PATU8902	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.14231590836474084	[403]	[497,734,297,1089]	1	hSpCas9	negative selection	8160537
33721237	33721260	21	+	27260156	PATU8902	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.42079710374428037	[476]	[1089,841,995,550]	4	hSpCas9	negative selection	8160538
33751851	33751874	21	-	27260156	PANC1	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.11126390941490105	[766]	[669,872,740,602]	1	hSpCas9	negative selection	8217532
33721196	33721219	21	-	27260156	PANC1	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.6747572158298083	[532]	[679,810,770,675]	9	hSpCas9	negative selection	8217533
33751885	33751908	21	+	27260156	PANC1	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.31136009504517526	[719]	[917,776,731,647]	5	hSpCas9	negative selection	8217534
33721249	33721272	21	-	27260156	PANC1	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.3309157625254414	[967]	[578,972,587,572]	-5	hSpCas9	negative selection	8281787
33722632	33722655	21	-	27260156	PANC1	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.060183715402169574	[403]	[202,507,297,351]	-1	hSpCas9	negative selection	8281788
33721237	33721260	21	+	27260156	PANC1	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.46361444824076303	[476]	[556,680,413,612]	7	hSpCas9	negative selection	8281789
33751851	33751874	21	-	27260156	PANC0813	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.299370259859455	[766]	[1381,890,951,1225]	5	hSpCas9	negative selection	8338783
33721196	33721219	21	-	27260156	PANC0813	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.7373647443272311	[532]	[1191,874,985,1128]	9	hSpCas9	negative selection	8338784
33751885	33751908	21	+	27260156	PANC0813	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.4257288837172457	[719]	[1157,838,1346,1197]	7	hSpCas9	negative selection	8338785
33721249	33721272	21	-	27260156	PANC0813	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.08787779111881433	[967]	[1295,1045,976,983]	-1	hSpCas9	negative selection	8403038
33722632	33722655	21	-	27260156	PANC0813	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.2879873656428776	[403]	[433,737,637,497]	4	hSpCas9	negative selection	8403039
33721237	33721260	21	+	27260156	PANC0813	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	-0.19669276977972644	[476]	[419,587,465,474]	-3	hSpCas9	negative selection	8403040
33751851	33751874	21	-	27260156	RDES	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.003516595691506086	[766]	[763,867,970,945]	0	hSpCas9	negative selection	8460034
33721196	33721219	21	-	27260156	RDES	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.79410586750599	[532]	[840,1028,1000,1457]	9	hSpCas9	negative selection	8460035
33751885	33751908	21	+	27260156	RDES	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.5349086297323387	[719]	[1005,1301,1057,1460]	8	hSpCas9	negative selection	8460036
33721249	33721272	21	-	27260156	RDES	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.35335677981574554	[967]	[811,773,801,1127]	-6	hSpCas9	negative selection	8524289
33722632	33722655	21	-	27260156	RDES	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.161120273536985	[403]	[446,557,558,508]	2	hSpCas9	negative selection	8524290
33721237	33721260	21	+	27260156	RDES	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.09632900121686007	[476]	[559,560,691,513]	1	hSpCas9	negative selection	8524291
33751851	33751874	21	-	27260156	PC3	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.05536126930216967	[766]	[439,907,1215,858]	1	hSpCas9	negative selection	8581285
33721196	33721219	21	-	27260156	PC3	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.6508002126169501	[532]	[637,848,1239,750]	9	hSpCas9	negative selection	8581286
33751885	33751908	21	+	27260156	PC3	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.26690692895840307	[719]	[611,900,1314,812]	6	hSpCas9	negative selection	8581287
33721249	33721272	21	-	27260156	PC3	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.22984011518384562	[967]	[610,881,1053,828]	-5	hSpCas9	negative selection	8645540
33722632	33722655	21	-	27260156	PC3	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.25550623087192803	[403]	[217,289,526,412]	-5	hSpCas9	negative selection	8645541
33721237	33721260	21	+	27260156	PC3	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	-0.28087514555943566	[476]	[307,388,440,437]	-6	hSpCas9	negative selection	8645542
33751851	33751874	21	-	27260156	PATU8988T	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	-0.10725848959990114	[766]	[582,786,713,675]	-2	hSpCas9	negative selection	8702536
33721196	33721219	21	-	27260156	PATU8988T	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.6673668659343137	[532]	[747,811,482,1268]	9	hSpCas9	negative selection	8702537
33751885	33751908	21	+	27260156	PATU8988T	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.3418876754779985	[719]	[898,971,820,840]	6	hSpCas9	negative selection	8702538
33721249	33721272	21	-	27260156	PATU8988T	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.02297622766542684	[967]	[1022,1027,625,1027]	0	hSpCas9	negative selection	8766791
33722632	33722655	21	-	27260156	PATU8988T	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.16707386106882666	[403]	[351,493,413,503]	3	hSpCas9	negative selection	8766792
33721237	33721260	21	+	27260156	PATU8988T	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.055127054871928496	[476]	[297,717,328,604]	1	hSpCas9	negative selection	8766793
33751851	33751874	21	-	27260156	T47D	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.12475492261078636	[766]	[957,861,911,1181]	2	hSpCas9	negative selection	8823787
33721196	33721219	21	-	27260156	T47D	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.5815613703135429	[532]	[882,926,1032,869]	9	hSpCas9	negative selection	8823788
33751885	33751908	21	+	27260156	T47D	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.2902897511200916	[719]	[973,1060,1040,1022]	6	hSpCas9	negative selection	8823789
33721249	33721272	21	-	27260156	T47D	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.1942521375038332	[967]	[980,841,965,1171]	-4	hSpCas9	negative selection	8888042
33722632	33722655	21	-	27260156	T47D	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.007909296166021068	[403]	[473,443,561,411]	0	hSpCas9	negative selection	8888043
33721237	33721260	21	+	27260156	T47D	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.010045291848369602	[476]	[444,464,600,739]	0	hSpCas9	negative selection	8888044
33751851	33751874	21	-	27260156	SU8686	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.3116948623254947	[766]	[862,1015,851,1051]	5	hSpCas9	negative selection	8945038
33721196	33721219	21	-	27260156	SU8686	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.9280303016640514	[532]	[985,870,1074,1122]	9	hSpCas9	negative selection	8945039
33751885	33751908	21	+	27260156	SU8686	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.5648254975471791	[719]	[1010,852,943,1509]	8	hSpCas9	negative selection	8945040
33721249	33721272	21	-	27260156	SU8686	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	0.061324972239210185	[967]	[872,973,1035,1159]	1	hSpCas9	negative selection	9009293
33722632	33722655	21	-	27260156	SU8686	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.19524513796818774	[403]	[254,327,369,478]	-3	hSpCas9	negative selection	9009294
33721237	33721260	21	+	27260156	SU8686	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.13848356828814667	[476]	[375,521,382,865]	2	hSpCas9	negative selection	9009295
33751851	33751874	21	-	27260156	SKES1	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.10722828330012701	[766]	[993,789,701,822]	2	hSpCas9	negative selection	9066289
33721196	33721219	21	-	27260156	SKES1	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.7080383816290083	[532]	[815,1116,771,792]	9	hSpCas9	negative selection	9066290
33751885	33751908	21	+	27260156	SKES1	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.149406817551338	[719]	[982,1003,705,564]	3	hSpCas9	negative selection	9066291
33721249	33721272	21	-	27260156	SKES1	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.21730379121808152	[967]	[717,882,823,873]	-5	hSpCas9	negative selection	9130544
33722632	33722655	21	-	27260156	SKES1	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.12215387046127832	[403]	[371,383,432,297]	-3	hSpCas9	negative selection	9130545
33721237	33721260	21	+	27260156	SKES1	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	-0.10867035068006542	[476]	[456,479,399,431]	-2	hSpCas9	negative selection	9130546
33751851	33751874	21	-	27260156	TOV112D	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.0029357170747185135	[766]	[647,1202,766,561]	0	hSpCas9	negative selection	9187540
33721196	33721219	21	-	27260156	TOV112D	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.7744765096782316	[532]	[901,1136,599,1061]	9	hSpCas9	negative selection	9187541
33751885	33751908	21	+	27260156	TOV112D	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.3370295640139753	[719]	[853,1125,1010,704]	6	hSpCas9	negative selection	9187542
33721249	33721272	21	-	27260156	TOV112D	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.20961323339402205	[967]	[1128,1022,790,488]	-4	hSpCas9	negative selection	9251795
33722632	33722655	21	-	27260156	TOV112D	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.17920802479244058	[403]	[413,540,308,580]	3	hSpCas9	negative selection	9251796
33721237	33721260	21	+	27260156	TOV112D	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.18980057839856646	[476]	[708,561,352,571]	3	hSpCas9	negative selection	9251797
33751851	33751874	21	-	27260156	TC71	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	-0.10908575772149087	[766]	[765,769,655,866]	-3	hSpCas9	negative selection	9308791
33721196	33721219	21	-	27260156	TC71	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.5967843196488383	[532]	[758,892,850,961]	9	hSpCas9	negative selection	9308792
33751885	33751908	21	+	27260156	TC71	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.027167826149374408	[719]	[732,837,698,885]	0	hSpCas9	negative selection	9308793
33721249	33721272	21	-	27260156	TC71	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.11127869536221935	[967]	[848,1059,918,1021]	-3	hSpCas9	negative selection	9373046
33722632	33722655	21	-	27260156	TC71	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	-0.10466137757286123	[403]	[395,396,332,492]	-3	hSpCas9	negative selection	9373047
33721237	33721260	21	+	27260156	TC71	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.12671501835701904	[476]	[557,562,574,534]	3	hSpCas9	negative selection	9373048
33751851	33751874	21	-	27260156	TC32	viability	TTAGTGTTTAGTTGTGACCCTGG	ITSN1	ENSG00000205726	0.3329147453875214	[766]	[714,807,1052,1097]	6	hSpCas9	negative selection	9430042
33721196	33721219	21	-	27260156	TC32	viability	CGCTCTTTCCTCTACAGTTATGG	ITSN1	ENSG00000205726	0.8360197315559028	[532]	[928,678,913,1090]	9	hSpCas9	negative selection	9430043
33751885	33751908	21	+	27260156	TC32	viability	CACAGTCATTTGATGTGGCCAGG	ITSN1	ENSG00000205726	0.4808103577084535	[719]	[1081,763,905,1011]	7	hSpCas9	negative selection	9430044
33721249	33721272	21	-	27260156	TC32	viability	CCAGTAATGAATCCAGATATTGG	ITSN1	ENSG00000205726	-0.3414933096800692	[967]	[773,513,834,799]	-6	hSpCas9	negative selection	9494297
33722632	33722655	21	-	27260156	TC32	viability	TACCATATCTGTGCTAAAACAGG	ITSN1	ENSG00000205726	0.2173849364313998	[403]	[484,281,634,424]	4	hSpCas9	negative selection	9494298
33721237	33721260	21	+	27260156	TC32	viability	CATAGTTTAAAGCCAATATCTGG	ITSN1	ENSG00000205726	0.16606443677546429	[476]	[386,530,650,435]	3	hSpCas9	negative selection	9494299
33735155	33735178	21	-	27869803	HPAFII	viability after 27 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.8340000060094731	[426]	[445,361,NaN]	6	hSpCas9	negative selection	9579129
33750283	33750306	21	-	27869803	HPAFII	viability after 27 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	0.7070393037165967	[176]	[248,70,NaN]	6	hSpCas9	negative selection	9579130
33755304	33755327	21	-	27869803	HPAFII	viability after 27 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-1.2099230693742313	[79]	[21,14,NaN]	-7	hSpCas9	negative selection	9579131
33761954	33761977	21	+	27869803	HPAFII	viability after 27 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.6000434297429021	[204]	[146,176,NaN]	5	hSpCas9	negative selection	9579132
33772269	33772292	21	+	27869803	HPAFII	viability after 27 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.2555682422227743	[410]	[108,240,NaN]	-2	hSpCas9	negative selection	9579133
33775011	33775034	21	+	27869803	HPAFII	viability after 27 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.8471078756621475	[61]	[20,89,NaN]	7	hSpCas9	negative selection	9579134
33735155	33735178	21	-	27869803	HPAFII	viability after 15 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.9560474184101176	[426]	[1020,808,NaN]	9	hSpCas9	negative selection	9661578
33750283	33750306	21	-	27869803	HPAFII	viability after 15 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	0.6823887255190771	[176]	[398,246,NaN]	7	hSpCas9	negative selection	9661579
33755304	33755327	21	-	27869803	HPAFII	viability after 15 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-0.9762360175485656	[79]	[76,22,NaN]	-7	hSpCas9	negative selection	9661580
33761954	33761977	21	+	27869803	HPAFII	viability after 15 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.6010281153951339	[204]	[475,245,NaN]	6	hSpCas9	negative selection	9661581
33772269	33772292	21	+	27869803	HPAFII	viability after 15 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.21895906061164638	[410]	[352,395,NaN]	-3	hSpCas9	negative selection	9661582
33775011	33775034	21	+	27869803	HPAFII	viability after 15 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	1.0127231215295835	[61]	[102,153,NaN]	9	hSpCas9	negative selection	9661583
33735155	33735178	21	-	27869803	ASPC1	viability after 36 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.8861330885517261	[1115]	[1245,683,371]	8	hSpCas9	negative selection	9744027
33750283	33750306	21	-	27869803	ASPC1	viability after 36 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-0.46407576831020847	[646]	[264,140,108]	-5	hSpCas9	negative selection	9744028
33755304	33755327	21	-	27869803	ASPC1	viability after 36 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	2.3343502296788405	[86]	[324,132,46]	9	hSpCas9	negative selection	9744029
33761954	33761977	21	+	27869803	ASPC1	viability after 36 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.35084092031816877	[487]	[154,212,261]	3	hSpCas9	negative selection	9744030
33772269	33772292	21	+	27869803	ASPC1	viability after 36 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.08944580926748757	[796]	[279,303,211]	-1	hSpCas9	negative selection	9744031
33775011	33775034	21	+	27869803	ASPC1	viability after 36 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	-0.01552775152303898	[229]	[82,139,27]	0	hSpCas9	negative selection	9744032
33735155	33735178	21	-	27869803	PATU8988S	viability after 35 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.5291270896020744	[1021]	[802,383,NaN]	6	hSpCas9	negative selection	9826476
33750283	33750306	21	-	27869803	PATU8988S	viability after 35 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-0.2946894868000232	[401]	[128,134,NaN]	-3	hSpCas9	negative selection	9826477
33755304	33755327	21	-	27869803	PATU8988S	viability after 35 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-0.44008736639392376	[95]	[27,28,NaN]	-4	hSpCas9	negative selection	9826478
33761954	33761977	21	+	27869803	PATU8988S	viability after 35 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.321118380654084	[417]	[130,289,NaN]	3	hSpCas9	negative selection	9826479
33772269	33772292	21	+	27869803	PATU8988S	viability after 35 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	0.7793494676554145	[759]	[463,586,NaN]	8	hSpCas9	negative selection	9826480
33775011	33775034	21	+	27869803	PATU8988S	viability after 35 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.9242120805545829	[221]	[24,314,NaN]	8	hSpCas9	negative selection	9826481
33735155	33735178	21	-	27869803	PATU8988S	viability after 31 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.3961396231338953	[1021]	[552,514,NaN]	5	hSpCas9	negative selection	9908925
33750283	33750306	21	-	27869803	PATU8988S	viability after 31 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	-0.6208142995822792	[401]	[105,101,NaN]	-6	hSpCas9	negative selection	9908926
33755304	33755327	21	-	27869803	PATU8988S	viability after 31 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	0.8159677968788173	[95]	[18,128,NaN]	8	hSpCas9	negative selection	9908927
33761954	33761977	21	+	27869803	PATU8988S	viability after 31 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.2914371799752635	[417]	[137,287,NaN]	3	hSpCas9	negative selection	9908928
33772269	33772292	21	+	27869803	PATU8988S	viability after 31 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	0.5149330125747618	[759]	[381,497,NaN]	6	hSpCas9	negative selection	9908929
33775011	33775034	21	+	27869803	PATU8988S	viability after 31 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	0.6544949138388626	[221]	[31,275,NaN]	7	hSpCas9	negative selection	9908930
33735155	33735178	21	-	27869803	HPAFII	viability after 35 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	1.022514995341174	[426]	[472,400,NaN]	7	hSpCas9	negative selection	9991374
33750283	33750306	21	-	27869803	HPAFII	viability after 35 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	1.0710420665235358	[176]	[231,138,NaN]	7	hSpCas9	negative selection	9991375
33755304	33755327	21	-	27869803	HPAFII	viability after 35 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-4.383253902270304	[79]	[0,2,NaN]	-9	hSpCas9	negative selection	9991376
33761954	33761977	21	+	27869803	HPAFII	viability after 35 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.8242476842032456	[204]	[163,205,NaN]	5	hSpCas9	negative selection	9991377
33772269	33772292	21	+	27869803	HPAFII	viability after 35 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.5600611075949253	[410]	[39,254,NaN]	-3	hSpCas9	negative selection	9991378
33775011	33775034	21	+	27869803	HPAFII	viability after 35 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	1.6450438842741577	[61]	[76,121,NaN]	9	hSpCas9	negative selection	9991379
33735155	33735178	21	-	27869803	HPAFII	viability after 31 days	CTGGTTGCTGTTTCATGACAGGG	ITSN1	ENSG00000205726	0.9987089316219183	[426]	[508,445,NaN]	7	hSpCas9	negative selection	10073823
33750283	33750306	21	-	27869803	HPAFII	viability after 31 days	GGCAGAGGTTGTATAACAGGGGG	ITSN1	ENSG00000205726	0.8177420700558243	[176]	[232,111,NaN]	6	hSpCas9	negative selection	10073824
33755304	33755327	21	-	27869803	HPAFII	viability after 31 days	GGAACAGCCCACTCTGCCACTGG	ITSN1	ENSG00000205726	-5.488556895212104	[79]	[0,0,NaN]	-9	hSpCas9	negative selection	10073825
33761954	33761977	21	+	27869803	HPAFII	viability after 31 days	AAGTTTACCACAGGCTCAGCTGG	ITSN1	ENSG00000205726	0.7723814837516358	[204]	[207,183,NaN]	5	hSpCas9	negative selection	10073826
33772269	33772292	21	+	27869803	HPAFII	viability after 31 days	GGAGCTAGAACGGCAGAGAGAGG	ITSN1	ENSG00000205726	-0.5991896034577632	[410]	[79,230,NaN]	-4	hSpCas9	negative selection	10073827
33775011	33775034	21	+	27869803	HPAFII	viability after 31 days	GATGTCGATTGACCACCCAAAGG	ITSN1	ENSG00000205726	1.9819379859139734	[61]	[46,235,NaN]	9	hSpCas9	negative selection	10073828
33718827	33718850	21	-	28162770	P31FUJ	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	0.10979945873773356	[193]	[245]	1	hSpCas9	negative selection	10176570
33735154	33735177	21	-	28162770	P31FUJ	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	0.3561456442579567	[481]	[724]	4	hSpCas9	negative selection	10176571
33750166	33750189	21	-	28162770	P31FUJ	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	0.7628457710459143	[165]	[330]	8	hSpCas9	negative selection	10176572
33750298	33750321	21	-	28162770	P31FUJ	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.19331474074495497	[226]	[304]	2	hSpCas9	negative selection	10176573
33765966	33765989	21	-	28162770	P31FUJ	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-3.2409761358600786	[176]	[21]	-9	hSpCas9	negative selection	10176574
33772248	33772271	21	+	28162770	P31FUJ	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	-0.03159511296855866	[146]	[168]	0	hSpCas9	negative selection	10176575
33772272	33772295	21	+	28162770	P31FUJ	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	0.7906567684096103	[121]	[247]	8	hSpCas9	negative selection	10176576
33811153	33811176	21	-	28162770	P31FUJ	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	-0.21745424008094266	[186]	[188]	-2	hSpCas9	negative selection	10176577
33813993	33814016	21	+	28162770	P31FUJ	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	0.198629733115134	[174]	[235]	2	hSpCas9	negative selection	10176578
33814047	33814070	21	-	28162770	P31FUJ	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	0.6611561581752967	[126]	[235]	7	hSpCas9	negative selection	10176579
33718827	33718850	21	-	28162770	TF1	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	NaN	[NaN]	[174]	1	hSpCas9	negative selection	10345936
33735154	33735177	21	-	28162770	TF1	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	NaN	[NaN]	[307]	1	hSpCas9	negative selection	10345937
33750166	33750189	21	-	28162770	TF1	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10345938
33750298	33750321	21	-	28162770	TF1	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10345939
33765966	33765989	21	-	28162770	TF1	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10345940
33772248	33772271	21	+	28162770	TF1	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	NaN	[NaN]	[209]	1	hSpCas9	negative selection	10345941
33772272	33772295	21	+	28162770	TF1	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10345942
33811153	33811176	21	-	28162770	TF1	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	NaN	[NaN]	[222]	1	hSpCas9	negative selection	10345943
33813993	33814016	21	+	28162770	TF1	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10345944
33814047	33814070	21	-	28162770	TF1	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	NaN	[NaN]	[143]	1	hSpCas9	negative selection	10345945
33718827	33718850	21	-	28162770	SKM1	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	0.8746061585280597	[57]	[187]	8	hSpCas9	negative selection	10515302
33735154	33735177	21	-	28162770	SKM1	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	0.10895665754834305	[106]	[203]	1	hSpCas9	negative selection	10515303
33750166	33750189	21	-	28162770	SKM1	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	0.5642768082754144	[56]	[148]	5	hSpCas9	negative selection	10515304
33750298	33750321	21	-	28162770	SKM1	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.07671496614081286	[58]	[109]	0	hSpCas9	negative selection	10515305
33765966	33765989	21	-	28162770	SKM1	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-1.8220016980220057	[53]	[26]	-8	hSpCas9	negative selection	10515306
33772248	33772271	21	+	28162770	SKM1	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	-0.6818240399737454	[48]	[53]	-5	hSpCas9	negative selection	10515307
33772272	33772295	21	+	28162770	SKM1	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	0.37064337992039054	[27]	[63]	3	hSpCas9	negative selection	10515308
33811153	33811176	21	-	28162770	SKM1	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	1.499926396865357	[34]	[174]	9	hSpCas9	negative selection	10515309
33813993	33814016	21	+	28162770	SKM1	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	-0.5088438127623752	[32]	[40]	-4	hSpCas9	negative selection	10515310
33814047	33814070	21	-	28162770	SKM1	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	0.27315553501833456	[21]	[46]	2	hSpCas9	negative selection	10515311
33718827	33718850	21	-	28162770	SKM1	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	0.8746061585280597	[57]	[187]	8	hSpCas9	negative selection	10684668
33735154	33735177	21	-	28162770	SKM1	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	0.10895665754834305	[106]	[203]	1	hSpCas9	negative selection	10684669
33750166	33750189	21	-	28162770	SKM1	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	0.5642768082754144	[56]	[148]	5	hSpCas9	negative selection	10684670
33750298	33750321	21	-	28162770	SKM1	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.07671496614081286	[58]	[109]	0	hSpCas9	negative selection	10684671
33765966	33765989	21	-	28162770	SKM1	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-1.8220016980220057	[53]	[26]	-8	hSpCas9	negative selection	10684672
33772248	33772271	21	+	28162770	SKM1	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	-0.6818240399737454	[48]	[53]	-5	hSpCas9	negative selection	10684673
33772272	33772295	21	+	28162770	SKM1	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	0.37064337992039054	[27]	[63]	3	hSpCas9	negative selection	10684674
33811153	33811176	21	-	28162770	SKM1	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	1.499926396865357	[34]	[174]	9	hSpCas9	negative selection	10684675
33813993	33814016	21	+	28162770	SKM1	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	-0.5088438127623752	[32]	[40]	-4	hSpCas9	negative selection	10684676
33814047	33814070	21	-	28162770	SKM1	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	0.27315553501833456	[21]	[46]	2	hSpCas9	negative selection	10684677
33718827	33718850	21	-	28162770	PL21	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	0.03639318797613206	[232]	[103]	0	hSpCas9	negative selection	10854034
33735154	33735177	21	-	28162770	PL21	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	0.400836964726449	[267]	[153]	3	hSpCas9	negative selection	10854035
33750166	33750189	21	-	28162770	PL21	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	0.33289482334109166	[165]	[90]	3	hSpCas9	negative selection	10854036
33750298	33750321	21	-	28162770	PL21	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	-0.23170617247607778	[258]	[95]	-2	hSpCas9	negative selection	10854037
33765966	33765989	21	-	28162770	PL21	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-1.2866424922929325	[212]	[37]	-7	hSpCas9	negative selection	10854038
33772248	33772271	21	+	28162770	PL21	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	-0.45436381948491306	[169]	[53]	-3	hSpCas9	negative selection	10854039
33772272	33772295	21	+	28162770	PL21	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	0.566921945160943	[75]	[48]	5	hSpCas9	negative selection	10854040
33811153	33811176	21	-	28162770	PL21	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	-0.29462507726025766	[123]	[43]	-2	hSpCas9	negative selection	10854041
33813993	33814016	21	+	28162770	PL21	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	1.2932490188808015	[104]	[111]	9	hSpCas9	negative selection	10854042
33814047	33814070	21	-	28162770	PL21	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	-0.13546341729511857	[52]	[20]	-1	hSpCas9	negative selection	10854043
33718827	33718850	21	-	28162770	P31FUJ	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	0.10979945873773356	[193]	[245]	1	hSpCas9	negative selection	11023400
33735154	33735177	21	-	28162770	P31FUJ	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	0.3561456442579567	[481]	[724]	4	hSpCas9	negative selection	11023401
33750166	33750189	21	-	28162770	P31FUJ	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	0.7628457710459143	[165]	[330]	8	hSpCas9	negative selection	11023402
33750298	33750321	21	-	28162770	P31FUJ	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.19331474074495497	[226]	[304]	2	hSpCas9	negative selection	11023403
33765966	33765989	21	-	28162770	P31FUJ	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-3.2409761358600786	[176]	[21]	-9	hSpCas9	negative selection	11023404
33772248	33772271	21	+	28162770	P31FUJ	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	-0.03159511296855866	[146]	[168]	0	hSpCas9	negative selection	11023405
33772272	33772295	21	+	28162770	P31FUJ	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	0.7906567684096103	[121]	[247]	8	hSpCas9	negative selection	11023406
33811153	33811176	21	-	28162770	P31FUJ	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	-0.21745424008094266	[186]	[188]	-2	hSpCas9	negative selection	11023407
33813993	33814016	21	+	28162770	P31FUJ	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	0.198629733115134	[174]	[235]	2	hSpCas9	negative selection	11023408
33814047	33814070	21	-	28162770	P31FUJ	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	0.6611561581752967	[126]	[235]	7	hSpCas9	negative selection	11023409
33718827	33718850	21	-	28162770	OCIAML5	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	-0.5461305087445358	[126]	[156]	-4	hSpCas9	negative selection	11192766
33735154	33735177	21	-	28162770	OCIAML5	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	1.0231151650171835	[183]	[674]	8	hSpCas9	negative selection	11192767
33750166	33750189	21	-	28162770	OCIAML5	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	0.9658190186857766	[77]	[274]	8	hSpCas9	negative selection	11192768
33750298	33750321	21	-	28162770	OCIAML5	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.10862050511117707	[92]	[180]	0	hSpCas9	negative selection	11192769
33765966	33765989	21	-	28162770	OCIAML5	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-3.1151009766977906	[143]	[29]	-9	hSpCas9	negative selection	11192770
33772248	33772271	21	+	28162770	OCIAML5	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	0.5402508519147634	[79]	[209]	5	hSpCas9	negative selection	11192771
33772272	33772295	21	+	28162770	OCIAML5	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	-0.0012100101698062637	[55]	[100]	0	hSpCas9	negative selection	11192772
33811153	33811176	21	-	28162770	OCIAML5	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	-0.1643903836942621	[130]	[210]	-1	hSpCas9	negative selection	11192773
33813993	33814016	21	+	28162770	OCIAML5	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	0.694676607626669	[50]	[148]	6	hSpCas9	negative selection	11192774
33814047	33814070	21	-	28162770	OCIAML5	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	-1.1396431609605822	[82]	[67]	-6	hSpCas9	negative selection	11192775
33718827	33718850	21	-	28162770	EOL1	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	0.6695506848021591	[357]	[299]	6	hSpCas9	negative selection	11362132
33735154	33735177	21	-	28162770	EOL1	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	-0.8497163640186471	[430]	[125]	-5	hSpCas9	negative selection	11362133
33750166	33750189	21	-	28162770	EOL1	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	-0.6400660837588191	[351]	[118]	-4	hSpCas9	negative selection	11362134
33750298	33750321	21	-	28162770	EOL1	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.10197346189549122	[404]	[228]	0	hSpCas9	negative selection	11362135
33765966	33765989	21	-	28162770	EOL1	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-2.728025635305299	[414]	[32]	-9	hSpCas9	negative selection	11362136
33772248	33772271	21	+	28162770	EOL1	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	0.9583624845627783	[252]	[258]	8	hSpCas9	negative selection	11362137
33772272	33772295	21	+	28162770	EOL1	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	0.3662532213114583	[133]	[90]	3	hSpCas9	negative selection	11362138
33811153	33811176	21	-	28162770	EOL1	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	2.3973007687056658	[146]	[407]	9	hSpCas9	negative selection	11362139
33813993	33814016	21	+	28162770	EOL1	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	0.35844429810069434	[113]	[76]	3	hSpCas9	negative selection	11362140
33814047	33814070	21	-	28162770	EOL1	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	0.15082362739421074	[105]	[61]	1	hSpCas9	negative selection	11362141
33718827	33718850	21	-	28162770	MOLM13	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	0.4918152207900593	[298]	[303]	3	hSpCas9	negative selection	11531498
33735154	33735177	21	-	28162770	MOLM13	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	-0.6794930512466453	[380]	[171]	-4	hSpCas9	negative selection	11531499
33750166	33750189	21	-	28162770	MOLM13	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	0.933974486413815	[235]	[325]	7	hSpCas9	negative selection	11531500
33750298	33750321	21	-	28162770	MOLM13	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	0.719021698322081	[283]	[337]	5	hSpCas9	negative selection	11531501
33765966	33765989	21	-	28162770	MOLM13	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-1.581863653652521	[235]	[56]	-7	hSpCas9	negative selection	11531502
33772248	33772271	21	+	28162770	MOLM13	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	0.3389916483623213	[233]	[213]	2	hSpCas9	negative selection	11531503
33772272	33772295	21	+	28162770	MOLM13	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	0.4045634461757496	[162]	[155]	3	hSpCas9	negative selection	11531504
33811153	33811176	21	-	28162770	MOLM13	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	1.2806577997885473	[151]	[266]	8	hSpCas9	negative selection	11531505
33813993	33814016	21	+	28162770	MOLM13	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	-1.181203456596293	[137]	[43]	-6	hSpCas9	negative selection	11531506
33814047	33814070	21	-	28162770	MOLM13	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	0.04817539505626178	[102]	[76]	0	hSpCas9	negative selection	11531507
33718827	33718850	21	-	28162770	HEL	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	-0.06352996494293271	[247]	[151]	0	hSpCas9	negative selection	11700864
33735154	33735177	21	-	28162770	HEL	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	-0.17717955152115944	[345]	[195]	-1	hSpCas9	negative selection	11700865
33750166	33750189	21	-	28162770	HEL	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	-1.7116107405793828	[224]	[43]	-7	hSpCas9	negative selection	11700866
33750298	33750321	21	-	28162770	HEL	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	-0.6270665318108728	[298]	[123]	-4	hSpCas9	negative selection	11700867
33765966	33765989	21	-	28162770	HEL	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-2.2728689807092706	[248]	[32]	-8	hSpCas9	negative selection	11700868
33772248	33772271	21	+	28162770	HEL	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	-0.3379821055047602	[222]	[112]	-2	hSpCas9	negative selection	11700869
33772272	33772295	21	+	28162770	HEL	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	-1.752562449217225	[120]	[22]	-7	hSpCas9	negative selection	11700870
33811153	33811176	21	-	28162770	HEL	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	0.5768508963438999	[111]	[106]	5	hSpCas9	negative selection	11700871
33813993	33814016	21	+	28162770	HEL	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	-0.919681100069711	[126]	[42]	-5	hSpCas9	negative selection	11700872
33814047	33814070	21	-	28162770	HEL	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	-1.3896826456920204	[89]	[21]	-7	hSpCas9	negative selection	11700873
33718827	33718850	21	-	28162770	MV411	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	-0.18749950593377343	[218]	[161]	-1	hSpCas9	negative selection	11870230
33735154	33735177	21	-	28162770	MV411	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	0.26980536381122977	[319]	[324]	2	hSpCas9	negative selection	11870231
33750166	33750189	21	-	28162770	MV411	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	0.7986117380476481	[143]	[210]	7	hSpCas9	negative selection	11870232
33750298	33750321	21	-	28162770	MV411	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	-0.208791635816178	[224]	[163]	-2	hSpCas9	negative selection	11870233
33765966	33765989	21	-	28162770	MV411	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-1.9670061174381819	[180]	[38]	-8	hSpCas9	negative selection	11870234
33772248	33772271	21	+	28162770	MV411	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	0.192575615748257	[133]	[128]	1	hSpCas9	negative selection	11870235
33772272	33772295	21	+	28162770	MV411	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	-0.5155232519163755	[111]	[65]	-4	hSpCas9	negative selection	11870236
33811153	33811176	21	-	28162770	MV411	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	-0.09586419489715414	[84]	[66]	0	hSpCas9	negative selection	11870237
33813993	33814016	21	+	28162770	MV411	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	0.2202160820477509	[106]	[104]	2	hSpCas9	negative selection	11870238
33814047	33814070	21	-	28162770	MV411	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	0.011809302289633505	[72]	[61]	0	hSpCas9	negative selection	11870239
33718827	33718850	21	-	28162770	MONOMAC1	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	-0.6524064403736156	[132]	[96]	-5	hSpCas9	negative selection	12039596
33735154	33735177	21	-	28162770	MONOMAC1	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	-0.40821787643937724	[234]	[202]	-4	hSpCas9	negative selection	12039597
33750166	33750189	21	-	28162770	MONOMAC1	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	0.40562765539506135	[107]	[163]	4	hSpCas9	negative selection	12039598
33750298	33750321	21	-	28162770	MONOMAC1	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	-0.35750151925279994	[151]	[135]	-3	hSpCas9	negative selection	12039599
33765966	33765989	21	-	28162770	MONOMAC1	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-1.684702146425795	[128]	[45]	-8	hSpCas9	negative selection	12039600
33772248	33772271	21	+	28162770	MONOMAC1	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	-0.01903854508155922	[98]	[111]	0	hSpCas9	negative selection	12039601
33772272	33772295	21	+	28162770	MONOMAC1	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	0.38792565366160253	[67]	[101]	4	hSpCas9	negative selection	12039602
33811153	33811176	21	-	28162770	MONOMAC1	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	-0.21721472899718408	[71]	[70]	-2	hSpCas9	negative selection	12039603
33813993	33814016	21	+	28162770	MONOMAC1	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	0.9905901561162176	[71]	[163]	8	hSpCas9	negative selection	12039604
33814047	33814070	21	-	28162770	MONOMAC1	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	0.0659975587742403	[44]	[53]	0	hSpCas9	negative selection	12039605
33718827	33718850	21	-	28162770	OCIAML2	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	1.9797282097696738	[28]	[633]	9	hSpCas9	negative selection	12208962
33735154	33735177	21	-	28162770	OCIAML2	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	-0.11640123845148881	[52]	[270]	-1	hSpCas9	negative selection	12208963
33750166	33750189	21	-	28162770	OCIAML2	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	-0.74816380077107	[39]	[131]	-5	hSpCas9	negative selection	12208964
33750298	33750321	21	-	28162770	OCIAML2	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	-0.164242581250577	[55]	[276]	-1	hSpCas9	negative selection	12208965
33765966	33765989	21	-	28162770	OCIAML2	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	-2.4233241104638044	[29]	[30]	-8	hSpCas9	negative selection	12208966
33772248	33772271	21	+	28162770	OCIAML2	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	0.5231382210463241	[28]	[230]	5	hSpCas9	negative selection	12208967
33772272	33772295	21	+	28162770	OCIAML2	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	0.12474929142433339	[22]	[138]	1	hSpCas9	negative selection	12208968
33811153	33811176	21	-	28162770	OCIAML2	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	0.8632709113112771	[23]	[241]	8	hSpCas9	negative selection	12208969
33813993	33814016	21	+	28162770	OCIAML2	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	0.8869221793759224	[11]	[122]	8	hSpCas9	negative selection	12208970
33814047	33814070	21	-	28162770	OCIAML2	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	-0.9527815203795418	[21]	[62]	-6	hSpCas9	negative selection	12208971
33718827	33718850	21	-	28162770	OCIAML3	viability	AGGTGTTGGAAACTGAGCCATGG	ITSN1	ENSG00000205726	0.25712897376135396	[50]	[183]	2	hSpCas9	negative selection	12378328
33735154	33735177	21	-	28162770	OCIAML3	viability	TGGTTGCTGTTTCATGACAGGGG	ITSN1	ENSG00000205726	0.6506147283957503	[91]	[435]	6	hSpCas9	negative selection	12378329
33750166	33750189	21	-	28162770	OCIAML3	viability	GGAGCAACAGCTGTAAGCGGTGG	ITSN1	ENSG00000205726	-0.43354296813091703	[50]	[113]	-3	hSpCas9	negative selection	12378330
33750298	33750321	21	-	28162770	OCIAML3	viability	GGATGAGCAAATGCAGGCAGAGG	ITSN1	ENSG00000205726	1.5561541062967192	[48]	[434]	9	hSpCas9	negative selection	12378331
33765966	33765989	21	-	28162770	OCIAML3	viability	GGAGGCAGGACAGGTGGCAGTGG	ITSN1	ENSG00000205726	0.4416162694065581	[49]	[204]	4	hSpCas9	negative selection	12378332
33772248	33772271	21	+	28162770	OCIAML3	viability	GAAGCAACTGGAAAAGCAGCGGG	ITSN1	ENSG00000205726	0.18232038611281653	[46]	[160]	1	hSpCas9	negative selection	12378333
33772272	33772295	21	+	28162770	OCIAML3	viability	GCTAGAACGGCAGAGAGAGGAGG	ITSN1	ENSG00000205726	0.31745568507417943	[20]	[78]	3	hSpCas9	negative selection	12378334
33811153	33811176	21	-	28162770	OCIAML3	viability	AGAGGTTACTGCCAAAGGGGCGG	ITSN1	ENSG00000205726	1.6790108540822528	[29]	[289]	9	hSpCas9	negative selection	12378335
33813993	33814016	21	+	28162770	OCIAML3	viability	GTGCCGGCCAGTTAAGGCAGAGG	ITSN1	ENSG00000205726	0.990954860396993	[19]	[119]	8	hSpCas9	negative selection	12378336
33814047	33814070	21	-	28162770	OCIAML3	viability	GCCTAGCACAGGAGACGGGGAGG	ITSN1	ENSG00000205726	0.5540909986649708	[36]	[163]	5	hSpCas9	negative selection	12378337