Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 83746
• Symbol: L3MBTL2
• Description: L3MBTL histone methyl-lysine binding protein 2

DataSource: http://genomecrispr.dkfz.de/#!/results/L3MBTL2

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
41227270	41227293	22	-	26472758	Jiyoye	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	0.17584983539941756	[26]	[22]	1	hSpCas9	negative selection	88417
41227219	41227242	22	+	26472758	Jiyoye	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	1.8784811004314623	[65]	[182]	8	hSpCas9	negative selection	88418
41219448	41219471	22	+	26472758	Jiyoye	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-0.5538304868782631	[145]	[74]	-4	hSpCas9	negative selection	88419
41220816	41220839	22	-	26472758	Jiyoye	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	0.13587335968847913	[69]	[57]	1	hSpCas9	negative selection	88420
41224052	41224075	22	+	26472758	Jiyoye	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-0.6632139463855247	[83]	[39]	-5	hSpCas9	negative selection	88421
41224202	41224225	22	-	26472758	Jiyoye	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	5.53645839845084	[0]	[34]	9	hSpCas9	negative selection	88422
41225879	41225902	22	-	26472758	Jiyoye	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	-0.23994359527785214	[165]	[105]	-2	hSpCas9	negative selection	88423
41227149	41227172	22	-	26472758	Jiyoye	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	-0.10183826598198431	[36]	[25]	0	hSpCas9	negative selection	88424
41227270	41227293	22	-	26472758	KBM7	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	0.5415052833700482	[81,51]	[53,36]	6	hSpCas9	negative selection	279535
41227219	41227242	22	+	26472758	KBM7	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	1.3054349316387648	[455,328]	[397,497]	9	hSpCas9	negative selection	279536
41219448	41219471	22	+	26472758	KBM7	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-1.084170482162222	[835,549]	[241,69]	-7	hSpCas9	negative selection	279537
41220816	41220839	22	-	26472758	KBM7	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	1.0750438103372686	[198,88]	[94,175]	9	hSpCas9	negative selection	279538
41224052	41224075	22	+	26472758	KBM7	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-1.0732111409642797	[494,472]	[71,140]	-7	hSpCas9	negative selection	279539
41224202	41224225	22	-	26472758	KBM7	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	0.9288609480632661	[161,157]	[110,172]	8	hSpCas9	negative selection	279540
41225879	41225902	22	-	26472758	KBM7	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	0.07438129411142597	[519,419]	[225,235]	0	hSpCas9	negative selection	279541
41227149	41227172	22	-	26472758	KBM7	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	0.6619296275512376	[220,89]	[162,64]	7	hSpCas9	negative selection	279542
41227270	41227293	22	-	26472758	Raji	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	1.4973300536896128	[28]	[18]	9	hSpCas9	negative selection	470653
41227219	41227242	22	+	26472758	Raji	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	2.5779161472441467	[152]	[211]	9	hSpCas9	negative selection	470654
41219448	41219471	22	+	26472758	Raji	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-1.5286531499418259	[459]	[36]	-8	hSpCas9	negative selection	470655
41220816	41220839	22	-	26472758	Raji	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	1.7114548590424603	[24]	[18]	9	hSpCas9	negative selection	470656
41224052	41224075	22	+	26472758	Raji	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-2.049120950306391	[320]	[17]	-8	hSpCas9	negative selection	470657
41224202	41224225	22	-	26472758	Raji	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	1.350240059269763	[119]	[70]	9	hSpCas9	negative selection	470658
41225879	41225902	22	-	26472758	Raji	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	0.8764996531435121	[283]	[120]	7	hSpCas9	negative selection	470659
41227149	41227172	22	-	26472758	Raji	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	1.1073835353735992	[55]	[27]	8	hSpCas9	negative selection	470660
41227270	41227293	22	-	26472758	K562	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	-0.27914322839056593	[45]	[31]	-2	hSpCas9	negative selection	661771
41227219	41227242	22	+	26472758	K562	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	0.6875893659293872	[291]	[396]	5	hSpCas9	negative selection	661772
41219448	41219471	22	+	26472758	K562	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-4.279143228390566	[620]	[26]	-9	hSpCas9	negative selection	661773
41220816	41220839	22	-	26472758	K562	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	-2.7912051820642745	[81]	[9]	-8	hSpCas9	negative selection	661774
41224052	41224075	22	+	26472758	K562	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-2.6624718679420716	[449]	[59]	-8	hSpCas9	negative selection	661775
41224202	41224225	22	-	26472758	K562	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	0.11040137969475938	[123]	[112]	0	hSpCas9	negative selection	661776
41225879	41225902	22	-	26472758	K562	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	-1.9791442373779389	[410]	[87]	-7	hSpCas9	negative selection	661777
41227149	41227172	22	-	26472758	K562	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	-1.1340928955872829	[64]	[24]	-6	hSpCas9	negative selection	661778
41205355	41205378	22	+	26627737	DLD1	viability	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	0.5782537148067517	[33]	[3,38,6]	6	hSpCas9	negative selection	817991
41219433	41219456	22	-	26627737	DLD1	viability	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	-0.37563832630791216	[449]	[101,76,139]	-4	hSpCas9	negative selection	817992
41205355	41205378	22	+	26627737	GBM cells	viability after 5 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-0.9084410471719182	[41]	[16,6]	-8	hSpCas9	negative selection	900306
41219433	41219456	22	-	26627737	GBM cells	viability after 5 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	-0.3878434417328459	[232]	[115,74]	-6	hSpCas9	negative selection	900307
41205355	41205378	22	+	26627737	GBM cells	viability after 13 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-1.1018221135634811	[41]	[3,15]	-8	hSpCas9	negative selection	982621
41219433	41219456	22	-	26627737	GBM cells	viability after 13 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	-0.058842937288805616	[232]	[170,80]	0	hSpCas9	negative selection	982622
41205355	41205378	22	+	26627737	GBM cells	viability after 21 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-0.4397877295070449	[41]	[20,12]	-4	hSpCas9	negative selection	1064936
41219433	41219456	22	-	26627737	GBM cells	viability after 21 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	-0.6303158904239216	[232]	[86,76]	-5	hSpCas9	negative selection	1064937
41205355	41205378	22	+	26627737	RPE1	viability after 9 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-1.4690062895203497	[67]	[8,5]	-8	hSpCas9	negative selection	1147251
41219433	41219456	22	-	26627737	RPE1	viability after 9 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	-0.7072470318568287	[725]	[150,123]	-5	hSpCas9	negative selection	1147252
41205355	41205378	22	+	26627737	RPE1	viability after 12 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	0.26808018906009545	[67]	[38,3]	1	hSpCas9	negative selection	1229566
41219433	41219456	22	-	26627737	RPE1	viability after 12 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	-0.6442402023477266	[725]	[117,131]	-4	hSpCas9	negative selection	1229567
41205355	41205378	22	+	26627737	RPE1	viability after 15 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-1.543346855871699	[67]	[0,11]	-7	hSpCas9	negative selection	1311881
41219433	41219456	22	-	26627737	RPE1	viability after 15 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	-0.6749544395539003	[725]	[92,162]	-4	hSpCas9	negative selection	1311882
41205355	41205378	22	+	26627737	RPE1	viability after 18 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-0.8951394165573645	[67]	[5,13]	-5	hSpCas9	negative selection	1394196
41219433	41219456	22	-	26627737	RPE1	viability after 18 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	-0.6312449815728643	[725]	[169,79]	-4	hSpCas9	negative selection	1394197
41205355	41205378	22	+	26627737	HeLa	viability after 8 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-0.2340113995929589	[92]	[9,25,59]	-2	hSpCas9	negative selection	1476511
41219433	41219456	22	-	26627737	HeLa	viability after 8 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	1.1933311162191491	[148]	[214,14,223]	8	hSpCas9	negative selection	1476512
41205355	41205378	22	+	26627737	HeLa	viability after 12 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-1.7103891828075009	[92]	[0,10,22]	-9	hSpCas9	negative selection	1558826
41219433	41219456	22	-	26627737	HeLa	viability after 12 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	0.8466026205839575	[148]	[123,68,143]	6	hSpCas9	negative selection	1558827
41205355	41205378	22	+	26627737	HeLa	viability after 15 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	1.0500621064274092	[92]	[88,31,116]	7	hSpCas9	negative selection	1641141
41219433	41219456	22	-	26627737	HeLa	viability after 15 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	0.0748758952100732	[148]	[11,35,150]	0	hSpCas9	negative selection	1641142
41205355	41205378	22	+	26627737	HeLa	viability after 18 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	1.035670704899097	[92]	[56,27,116]	7	hSpCas9	negative selection	1723456
41219433	41219456	22	-	26627737	HeLa	viability after 18 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	0.07140360836774184	[148]	[9,26,150]	0	hSpCas9	negative selection	1723457
41205355	41205378	22	+	26627737	HCT116	viability after 6 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-1.85708207709737	[63]	[5,0]	-8	hSpCas9	negative selection	1805771
41219433	41219456	22	-	26627737	HCT116	viability after 6 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	0.04281144486735067	[370]	[110,31]	0	hSpCas9	negative selection	1805772
41205355	41205378	22	+	26627737	HCT116	viability after 8 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	0.3595485042814528	[34]	[15,26,30]	4	hSpCas9	negative selection	1888086
41219433	41219456	22	-	26627737	HCT116	viability after 8 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	1.480651685459183	[113]	[180,167,176]	9	hSpCas9	negative selection	1888087
41205355	41205378	22	+	26627737	HCT116	viability after 9 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-4.0950101886465315	[63]	[0,0]	-9	hSpCas9	negative selection	1970401
41219433	41219456	22	-	26627737	HCT116	viability after 9 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	1.0798072389547972	[370]	[238,185]	7	hSpCas9	negative selection	1970402
41205355	41205378	22	+	26627737	HCT116	viability after 12 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	0.10784821988740445	[34]	[8,43,7]	1	hSpCas9	negative selection	2052716
41219433	41219456	22	-	26627737	HCT116	viability after 12 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	1.4305949251900958	[113]	[196,187,96]	9	hSpCas9	negative selection	2052717
41205355	41205378	22	+	26627737	HCT116	viability after 15 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	0.7239958014466619	[34]	[59,20,21]	6	hSpCas9	negative selection	2135031
41219433	41219456	22	-	26627737	HCT116	viability after 15 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	0.8179907328929471	[113]	[135,116,95]	7	hSpCas9	negative selection	2135032
41205355	41205378	22	+	26627737	HCT116	viability after 18 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-0.5711816579061701	[34]	[4,23,3]	-5	hSpCas9	negative selection	2217346
41219433	41219456	22	-	26627737	HCT116	viability after 18 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	1.5665589270193176	[113]	[254,148,82]	9	hSpCas9	negative selection	2217347
41205373	41205396	22	-	24336569	HL60	viability	CCTTCTCACCTCAATACTCCGGG	L3MBTL2	ENSG00000100395	0.7683071829021126	[315]	[1138]	6	hSpCas9	negative selection	2274346
41205373	41205396	22	-	24336569	KBM7	viability	CCTTCTCACCTCAATACTCCGGG	L3MBTL2	ENSG00000100395	-0.9241919749486797	[358]	[515]	-6	hSpCas9	negative selection	2341523
41220538	41220561	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAATCAGCCGGGCGTGGTGGCAG	L3MBTL2	ENSG00000100395	2.666493729320144	[0,0]	[2,0]	8	dCas9-VP64	positive selection	2406251
41205209	41205232	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGGGAGCAGGCACGGAACCGG	L3MBTL2	ENSG00000100395	-0.7982148280700452	[2,116]	[2,11]	-4	dCas9-VP64	positive selection	2458492
41220538	41220561	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAATCAGCCGGGCGTGGTGGCAG	L3MBTL2	ENSG00000100395	4.409340511338286	[107,137]	[18,1641]	9	dCas9-VP64	positive selection	2501506
41205209	41205232	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGGGAGCAGGCACGGAACCGG	L3MBTL2	ENSG00000100395	-1.344579233256087	[132,176]	[16,21]	-9	dCas9-VP64	positive selection	2553747
41219417	41219440	22	+	27260157	DLD1	viability	AGGTCCCACTCTATGACCAGTGG	L3MBTL2	ENSG00000100395	-0.172493867904028	[]	[]	-1	hSpCas9	negative selection	2575591
41205373	41205396	22	-	27260157	DLD1	viability	CCTTCTCACCTCAATACTCCGGG	L3MBTL2	ENSG00000100395	-0.659489630691206	[]	[]	-5	hSpCas9	negative selection	2581411
41219493	41219516	22	-	27260157	DLD1	viability	CGATCCAGTACACCCGGCTGGGG	L3MBTL2	ENSG00000100395	0.541494973398557	[]	[]	8	hSpCas9	negative selection	2619613
41205372	41205395	22	-	27260157	DLD1	viability	CTTCTCACCTCAATACTCCGGGG	L3MBTL2	ENSG00000100395	0.184323410511236	[]	[]	3	hSpCas9	negative selection	2643599
41219417	41219440	22	+	27260157	HT1080	viability	AGGTCCCACTCTATGACCAGTGG	L3MBTL2	ENSG00000100395	-0.790345638552568	[]	[]	-8	hSpCas9	negative selection	2651721
41205373	41205396	22	-	27260157	HT1080	viability	CCTTCTCACCTCAATACTCCGGG	L3MBTL2	ENSG00000100395	-0.375892027654943	[]	[]	-7	hSpCas9	negative selection	2657541
41219493	41219516	22	-	27260157	HT1080	viability	CGATCCAGTACACCCGGCTGGGG	L3MBTL2	ENSG00000100395	0.0248985442173122	[]	[]	0	hSpCas9	negative selection	2695743
41205372	41205395	22	-	27260157	HT1080	viability	CTTCTCACCTCAATACTCCGGGG	L3MBTL2	ENSG00000100395	0.0781943540998933	[]	[]	0	hSpCas9	negative selection	2719729
41219417	41219440	22	+	27260157	MKN45	viability	AGGTCCCACTCTATGACCAGTGG	L3MBTL2	ENSG00000100395	-0.680660667302163	[]	[]	-7	hSpCas9	negative selection	2727851
41205373	41205396	22	-	27260157	MKN45	viability	CCTTCTCACCTCAATACTCCGGG	L3MBTL2	ENSG00000100395	-0.342259707413068	[]	[]	-1	hSpCas9	negative selection	2733671
41219493	41219516	22	-	27260157	MKN45	viability	CGATCCAGTACACCCGGCTGGGG	L3MBTL2	ENSG00000100395	-0.743539617294643	[]	[]	-7	hSpCas9	negative selection	2771873
41205372	41205395	22	-	27260157	MKN45	viability	CTTCTCACCTCAATACTCCGGGG	L3MBTL2	ENSG00000100395	-1.55848237332263	[]	[]	-9	hSpCas9	negative selection	2795859
41219417	41219440	22	+	27260157	RKO	viability	AGGTCCCACTCTATGACCAGTGG	L3MBTL2	ENSG00000100395	0.0483887087102414	[]	[]	0	hSpCas9	negative selection	2803981
41205373	41205396	22	-	27260157	RKO	viability	CCTTCTCACCTCAATACTCCGGG	L3MBTL2	ENSG00000100395	-0.921964189461695	[]	[]	-8	hSpCas9	negative selection	2809801
41219493	41219516	22	-	27260157	RKO	viability	CGATCCAGTACACCCGGCTGGGG	L3MBTL2	ENSG00000100395	-0.551757987935923	[]	[]	-7	hSpCas9	negative selection	2848003
41205372	41205395	22	-	27260157	RKO	viability	CTTCTCACCTCAATACTCCGGGG	L3MBTL2	ENSG00000100395	-0.741117955023045	[]	[]	-7	hSpCas9	negative selection	2871989
41219417	41219440	22	+	27260157	SF268	viability	AGGTCCCACTCTATGACCAGTGG	L3MBTL2	ENSG00000100395	0.339388426736487	[]	[]	4	hSpCas9	negative selection	2880111
41205373	41205396	22	-	27260157	SF268	viability	CCTTCTCACCTCAATACTCCGGG	L3MBTL2	ENSG00000100395	-0.61261653096309	[]	[]	-5	hSpCas9	negative selection	2885931
41219493	41219516	22	-	27260157	SF268	viability	CGATCCAGTACACCCGGCTGGGG	L3MBTL2	ENSG00000100395	0.722457102816188	[]	[]	8	hSpCas9	negative selection	2924133
41205372	41205395	22	-	27260157	SF268	viability	CTTCTCACCTCAATACTCCGGGG	L3MBTL2	ENSG00000100395	-0.425278230819065	[]	[]	-3	hSpCas9	negative selection	2948119
41221217	41221240	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATGAGGTAGCCCTTCCAGTCGG	L3MBTL2	ENSG00000100395	0.35583921620703096	[3,3]	[3,4]	7	hSpCas9	positive selection	2998717
41205372	41205395	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCTCACCTCAATACTCCGGGG	L3MBTL2	ENSG00000100395	0.2917668991092262	[3,3]	[3,3]	6	hSpCas9	positive selection	2998718
41221217	41221240	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATGAGGTAGCCCTTCCAGTCGG	L3MBTL2	ENSG00000100395	0.3460434791607191	[3,3]	[3,2]	6	hSpCas9	positive selection	3066575
41205372	41205395	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCTCACCTCAATACTCCGGGG	L3MBTL2	ENSG00000100395	0.7017795569055288	[3,3]	[4,3]	9	hSpCas9	positive selection	3066576
41221217	41221240	22	-	26780180	HT29	viability (Avana library 4 designs)	CATGAGGTAGCCCTTCCAGTCGG	L3MBTL2	ENSG00000100395	1.73156573638469	[]	[]	6	hSpCas9	negative selection	3436219
41205372	41205395	22	-	26780180	HT29	viability (Avana library 4 designs)	CTTCTCACCTCAATACTCCGGGG	L3MBTL2	ENSG00000100395	1.01848003547208	[]	[]	4	hSpCas9	negative selection	3436220
41205372	41205395	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCTCACCTCAATACTCCGGGG	L3MBTL2	ENSG00000100395	0.27018633073704	[]	[]	0	hSpCas9	negative selection	3524302
41221217	41221240	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATGAGGTAGCCCTTCCAGTCGG	L3MBTL2	ENSG00000100395	0.227127807743065	[]	[]	0	hSpCas9	negative selection	3524303
41205372	41205395	22	-	26780180	A375	viability (Avana lentiGuide)	CTTCTCACCTCAATACTCCGGGG	L3MBTL2	ENSG00000100395	3.22269279024007	[]	[]	3	hSpCas9	negative selection	3632961
41221217	41221240	22	-	26780180	A375	viability (Avana lentiGuide)	CATGAGGTAGCCCTTCCAGTCGG	L3MBTL2	ENSG00000100395	4.52211906068698	[]	[]	4	hSpCas9	negative selection	3632962
41205372	41205395	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCTCACCTCAATACTCCGGGG	L3MBTL2	ENSG00000100395	-0.43771139278469334	[4]	[2,3]	-6	hSpCas9	positive selection	3741620
41221217	41221240	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGAGGTAGCCCTTCCAGTCGG	L3MBTL2	ENSG00000100395	-0.17875078391386112	[4]	[4,3]	-3	hSpCas9	positive selection	3741621
41205372	41205395	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCTCACCTCAATACTCCGGGG	L3MBTL2	ENSG00000100395	-0.07543043874328059	[5]	[3,4]	-1	hSpCas9	positive selection	3850227
41221217	41221240	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGAGGTAGCCCTTCCAGTCGG	L3MBTL2	ENSG00000100395	-0.2197617702340059	[5]	[5,2]	-3	hSpCas9	positive selection	3850228
41220852	41220875	22	-	26780180	A375	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.513833514288086	[]	[]	1	hSpCas9	negative selection	3956027
41220821	41220844	22	-	26780180	A375	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	1.11489668786053	[]	[]	5	hSpCas9	negative selection	3956028
41220852	41220875	22	-	26780180	HT29	viability (GeCKOv2 library)	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	1.02828015811706	[]	[]	5	hSpCas9	negative selection	4063993
41220821	41220844	22	-	26780180	HT29	viability (GeCKOv2 library)	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	1.34014115859049	[]	[]	6	hSpCas9	negative selection	4063994
41220852	41220875	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.3328581919997975	[3]	[4,2]	6	hSpCas9	positive selection	4279569
41220821	41220844	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	0.48017701586045425	[2]	[1,3]	8	hSpCas9	positive selection	4279571
41219494	41219516	22	-	27760321	OCIAML3	viability	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	-0.3842170606186559	[1048,822]	[577,529]	-4	hSpCas9	negative selection	4413588
41220859	41220881	22	-	27760321	OCIAML3	viability	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	-0.8322105174934536	[610,553]	[223,296]	-7	hSpCas9	negative selection	4413589
41221203	41221225	22	+	27760321	OCIAML3	viability	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	0.10565872226575079	[884,660]	[574,735]	1	hSpCas9	negative selection	4413590
41224118	41224140	22	+	27760321	OCIAML3	viability	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	0.06635265935073598	[354,397]	[193,462]	0	hSpCas9	negative selection	4413591
41219494	41219516	22	-	27760321	OCIAML2	viability	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	0.06301717108903748	[1048,822]	[550,1094]	0	hSpCas9	negative selection	4497051
41220859	41220881	22	-	27760321	OCIAML2	viability	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	-0.804162007466187	[610,553]	[213,342]	-7	hSpCas9	negative selection	4497052
41221203	41221225	22	+	27760321	OCIAML2	viability	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	0.1732048026900973	[884,660]	[632,785]	2	hSpCas9	negative selection	4497053
41224118	41224140	22	+	27760321	OCIAML2	viability	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	0.2288484950235835	[354,397]	[329,398]	3	hSpCas9	negative selection	4497054
41219494	41219516	22	-	27760321	MV411	viability	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	-0.34585473587431104	[1048,822]	[465,507]	-2	hSpCas9	negative selection	4580514
41220859	41220881	22	-	27760321	MV411	viability	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	-0.38695214900751357	[610,553]	[228,390]	-3	hSpCas9	negative selection	4580515
41221203	41221225	22	+	27760321	MV411	viability	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	1.952367996305035	[884,660]	[2379,1321]	9	hSpCas9	negative selection	4580516
41224118	41224140	22	+	27760321	MV411	viability	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	0.9563085115284296	[354,397]	[636,258]	7	hSpCas9	negative selection	4580517
41219494	41219516	22	-	27760321	HL60	viability	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	0.4471845925591964	[1048,822]	[1052,1016]	5	hSpCas9	negative selection	4663977
41220859	41220881	22	-	27760321	HL60	viability	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	0.23263452430321652	[610,553]	[514,604]	3	hSpCas9	negative selection	4663978
41221203	41221225	22	+	27760321	HL60	viability	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	0.6209116857031226	[884,660]	[1068,849]	7	hSpCas9	negative selection	4663979
41224118	41224140	22	+	27760321	HL60	viability	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	0.8501306621171519	[354,397]	[569,546]	8	hSpCas9	negative selection	4663980
41219494	41219516	22	-	27760321	HT1080	viability	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	-0.13503445340863363	[822,641]	[280,248]	0	hSpCas9	negative selection	4747440
41220859	41220881	22	-	27760321	HT1080	viability	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	0.9481751769856818	[553,432]	[312,451]	5	hSpCas9	negative selection	4747441
41221203	41221225	22	+	27760321	HT1080	viability	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	-0.41335545209068003	[660,515]	[218,128]	-2	hSpCas9	negative selection	4747442
41224118	41224140	22	+	27760321	HT1080	viability	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	1.3142965355424159	[397,310]	[397,299]	7	hSpCas9	negative selection	4747443
41219494	41219516	22	-	27760321	HT29	viability after 7 days	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	0.5132451627638837	[822,641]	[1553,1150,1354]	7	hSpCas9	negative selection	4830903
41220859	41220881	22	-	27760321	HT29	viability after 7 days	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	0.5021416784601913	[553,432]	[812,1076,795]	7	hSpCas9	negative selection	4830904
41221203	41221225	22	+	27760321	HT29	viability after 7 days	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	0.36038521293141956	[660,515]	[1064,951,910]	5	hSpCas9	negative selection	4830905
41224118	41224140	22	+	27760321	HT29	viability after 7 days	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	0.7746827071662062	[397,310]	[578,578,1139]	9	hSpCas9	negative selection	4830906
41219494	41219516	22	-	27760321	HT29	viability after 25 days	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	0.47797091113443435	[822,641]	[995,987,1563]	5	hSpCas9	negative selection	4914366
41220859	41220881	22	-	27760321	HT29	viability after 25 days	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	0.1666470546521458	[553,432]	[755,497,636]	1	hSpCas9	negative selection	4914367
41221203	41221225	22	+	27760321	HT29	viability after 25 days	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	0.8659291572902554	[660,515]	[1079,1064,1575]	8	hSpCas9	negative selection	4914368
41224118	41224140	22	+	27760321	HT29	viability after 25 days	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	0.21997300790823052	[397,310]	[345,405,693]	2	hSpCas9	negative selection	4914369
41219494	41219516	22	-	27760321	HT29	viability after 22 days	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	0.6205920911165881	[822,641]	[1429,1198,1272]	7	hSpCas9	negative selection	4997829
41220859	41220881	22	-	27760321	HT29	viability after 22 days	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	-0.30973587086645377	[553,432]	[467,529,381]	-3	hSpCas9	negative selection	4997830
41221203	41221225	22	+	27760321	HT29	viability after 22 days	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	0.7547210635164665	[660,515]	[1431,868,1134]	8	hSpCas9	negative selection	4997831
41224118	41224140	22	+	27760321	HT29	viability after 22 days	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	-0.29671114721285674	[397,310]	[139,344,522]	-3	hSpCas9	negative selection	4997832
41219494	41219516	22	-	27760321	HT29	viability after 19 days	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	0.3582389797725978	[822,641]	[1350,910,990]	3	hSpCas9	negative selection	5081292
41220859	41220881	22	-	27760321	HT29	viability after 19 days	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	0.23673177373495036	[553,432]	[502,597,868]	2	hSpCas9	negative selection	5081293
41221203	41221225	22	+	27760321	HT29	viability after 19 days	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	0.5675181929596622	[660,515]	[1154,930,924]	6	hSpCas9	negative selection	5081294
41224118	41224140	22	+	27760321	HT29	viability after 19 days	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	-0.05059068661628934	[397,310]	[482,314,385]	0	hSpCas9	negative selection	5081295
41219494	41219516	22	-	27760321	HT29	viability after 16 days	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	0.2761090408264453	[822,641]	[992,1028,953]	3	hSpCas9	negative selection	5164755
41220859	41220881	22	-	27760321	HT29	viability after 16 days	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	-0.25420508099464734	[553,432]	[519,471,401]	-3	hSpCas9	negative selection	5164756
41221203	41221225	22	+	27760321	HT29	viability after 16 days	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	0.7227560634118086	[660,515]	[1134,904,1228]	8	hSpCas9	negative selection	5164757
41224118	41224140	22	+	27760321	HT29	viability after 16 days	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	-0.22478537409752414	[397,310]	[314,411,286]	-3	hSpCas9	negative selection	5164758
41219494	41219516	22	-	27760321	HT29	viability after 13 days	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	0.4920106193302598	[822,641]	[1564,820,1197]	6	hSpCas9	negative selection	5248218
41220859	41220881	22	-	27760321	HT29	viability after 13 days	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	0.17621668809174706	[553,432]	[738,579,622]	2	hSpCas9	negative selection	5248219
41221203	41221225	22	+	27760321	HT29	viability after 13 days	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	0.37550582348278994	[660,515]	[702,925,1019]	5	hSpCas9	negative selection	5248220
41224118	41224140	22	+	27760321	HT29	viability after 13 days	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	0.17324055360562268	[397,310]	[385,517,485]	2	hSpCas9	negative selection	5248221
41219494	41219516	22	-	27760321	HT29	viability after 10 days	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	0.5205585288682109	[822,641]	[1187,1456,1294]	7	hSpCas9	negative selection	5331681
41220859	41220881	22	-	27760321	HT29	viability after 10 days	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	0.27395365292794305	[553,432]	[731,888,620]	3	hSpCas9	negative selection	5331682
41221203	41221225	22	+	27760321	HT29	viability after 10 days	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	0.41127248976998687	[660,515]	[1018,911,997]	5	hSpCas9	negative selection	5331683
41224118	41224140	22	+	27760321	HT29	viability after 10 days	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	0.2559773396390413	[397,310]	[452,488,639]	3	hSpCas9	negative selection	5331684
41219494	41219516	22	-	27760321	MOLM13	viability	CGATCCAGTACACCCGGCTGGG	L3MBTL2	ENSG00000100395	0.32112209228381894	[1048,822]	[562,733]	2	hSpCas9	negative selection	5415144
41220859	41220881	22	-	27760321	MOLM13	viability	TCATCAACTCACTCCGTGGGGG	L3MBTL2	ENSG00000100395	-0.28190572510280365	[610,553]	[429,133]	-2	hSpCas9	negative selection	5415145
41221203	41221225	22	+	27760321	MOLM13	viability	CCATGCCAAGTTCACCGACTGG	L3MBTL2	ENSG00000100395	1.1494960500812756	[884,660]	[593,1269]	7	hSpCas9	negative selection	5415146
41224118	41224140	22	+	27760321	MOLM13	viability	AGTAATCGGGGGTCGCCTACGG	L3MBTL2	ENSG00000100395	1.3540026424446254	[354,397]	[764,361]	8	hSpCas9	negative selection	5415147
41205336	41205359	22	+	27661255	K562	viability	GGTGACGCTTGGCGAAACTGAGG	L3MBTL2	ENSG00000100395	0.32349386169896976	[990,1257]	[1264,994]	9	dCas9-KRAB	negative selection	5489654
41205355	41205378	22	+	27661255	K562	viability	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	0.09804725988596175	[726,806]	[714,602]	3	dCas9-KRAB	negative selection	5489655
41205365	41205388	22	+	27661255	K562	viability	GGAGAAGCCCCGGAGTATTGAGG	L3MBTL2	ENSG00000100395	0.06742462197097027	[899,893]	[819,691]	2	dCas9-KRAB	negative selection	5489656
41220852	41220875	22	-	27260156	BXPC3	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.14049242401532425	[715]	[714,815,968,807]	3	hSpCas9	negative selection	5552029
41220821	41220844	22	-	27260156	BXPC3	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.06367372855847364	[313]	[250,322,280,417]	-1	hSpCas9	negative selection	5552031
41220852	41220875	22	-	27260156	A673	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.013970776025395204	[715]	[967,684,905,862]	0	hSpCas9	negative selection	5673280
41220821	41220844	22	-	27260156	A673	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.26576249062376056	[313]	[233,274,313,428]	-6	hSpCas9	negative selection	5673282
41220852	41220875	22	-	27260156	A375	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.07839203294162933	[715]	[749,1129,901,790]	1	hSpCas9	negative selection	5794531
41220821	41220844	22	-	27260156	A375	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.22998320905130187	[313]	[321,450,294,212]	-3	hSpCas9	negative selection	5794533
41220852	41220875	22	-	27260156	COLO741	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.0680961123779582	[715]	[926,952,749]	-1	hSpCas9	negative selection	5915782
41220821	41220844	22	-	27260156	COLO741	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.03727194550766566	[313]	[377,332,454]	-1	hSpCas9	negative selection	5915784
41220852	41220875	22	-	27260156	CAL120	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.3636441467080179	[715]	[1287,1023,1147]	5	hSpCas9	negative selection	6037033
41220821	41220844	22	-	27260156	CAL120	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.4245390250156178	[313]	[276,350,243]	-6	hSpCas9	negative selection	6037035
41220852	41220875	22	-	27260156	CADOES1	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.015194349495155524	[715]	[577,736,614,707]	0	hSpCas9	negative selection	6158284
41220821	41220844	22	-	27260156	CADOES1	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.08412566694083878	[313]	[234,272,243,352]	-1	hSpCas9	negative selection	6158286
41220852	41220875	22	-	27260156	EWS502	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.0781518035040526	[715]	[749,633,688,802]	-1	hSpCas9	negative selection	6279535
41220821	41220844	22	-	27260156	EWS502	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.22820779945598824	[313]	[272,430,218,199]	-4	hSpCas9	negative selection	6279537
41220852	41220875	22	-	27260156	EW8	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.2738811600865434	[715]	[923,669,485,784]	5	hSpCas9	negative selection	6400786
41220821	41220844	22	-	27260156	EW8	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	0.04421500300055936	[313]	[238,298,210,305]	0	hSpCas9	negative selection	6400788
41220852	41220875	22	-	27260156	CORL105	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.24717418647321077	[715]	[1058,1016,1124,800]	4	hSpCas9	negative selection	6522037
41220821	41220844	22	-	27260156	CORL105	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.319825550197934	[313]	[231,153,458,358]	-5	hSpCas9	negative selection	6522039
41220852	41220875	22	-	27260156	HS294T	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.22146145939908846	[715]	[282,192,247,218]	-3	hSpCas9	negative selection	6643288
41220821	41220844	22	-	27260156	HS294T	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.6884815660819039	[313]	[82,68,70,77]	-7	hSpCas9	negative selection	6643290
41220852	41220875	22	-	27260156	HCC44	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.4343634568419291	[715]	[1258,934,1173,1052]	7	hSpCas9	negative selection	6764539
41220821	41220844	22	-	27260156	HCC44	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.3745567320737532	[313]	[292,222,307,283]	-5	hSpCas9	negative selection	6764541
41220852	41220875	22	-	27260156	G402	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.008835993510211915	[715]	[1124,851,934,606]	0	hSpCas9	negative selection	6885790
41220821	41220844	22	-	27260156	G402	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	0.12664763000091966	[313]	[561,276,360,480]	1	hSpCas9	negative selection	6885792
41220852	41220875	22	-	27260156	L33	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.13816374078915034	[715]	[636,270,460,571]	-3	hSpCas9	negative selection	7007041
41220821	41220844	22	-	27260156	L33	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.2969464177551968	[313]	[238,101,210,199]	-6	hSpCas9	negative selection	7007043
41220852	41220875	22	-	27260156	K562	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.4963240286204832	[715]	[1014,823,537,1176]	6	hSpCas9	negative selection	7128292
41220821	41220844	22	-	27260156	K562	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	0.4127751510316948	[313]	[437,250,143,618]	5	hSpCas9	negative selection	7128294
41220852	41220875	22	-	27260156	HT29	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.02235078331653284	[715]	[822,895,915,889]	0	hSpCas9	negative selection	7249543
41220821	41220844	22	-	27260156	HT29	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.03190195085390024	[313]	[320,469,330,372]	0	hSpCas9	negative selection	7249545
41220852	41220875	22	-	27260156	MHHES1	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.08432679166737356	[715]	[684,825,663,829]	-1	hSpCas9	negative selection	7370794
41220821	41220844	22	-	27260156	MHHES1	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.25947504536631794	[313]	[301,224,316,318]	-5	hSpCas9	negative selection	7370796
41220852	41220875	22	-	27260156	MEWO	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.17391183269425192	[715]	[788,617,866]	4	hSpCas9	negative selection	7492045
41220821	41220844	22	-	27260156	MEWO	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.21723241322097198	[313]	[244,161,349]	-5	hSpCas9	negative selection	7492047
41220852	41220875	22	-	27260156	LNCAPCLONEFGC	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.004658160273702583	[715]	[546,616,939,528]	0	hSpCas9	negative selection	7613296
41220821	41220844	22	-	27260156	LNCAPCLONEFGC	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.42122653518824915	[313]	[270,196,202,176]	-6	hSpCas9	negative selection	7613298
41220852	41220875	22	-	27260156	PANC0327	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.23903246346770102	[715]	[875,746,681,707]	3	hSpCas9	negative selection	7734547
41220821	41220844	22	-	27260156	PANC0327	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.7111451752001885	[313]	[108,296,108,144]	-7	hSpCas9	negative selection	7734549
41220852	41220875	22	-	27260156	NCIH2009	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.1953288226556703	[715]	[962,776,898]	-3	hSpCas9	negative selection	7855798
41220821	41220844	22	-	27260156	NCIH2009	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.915690554076388	[313]	[264,214,223]	-8	hSpCas9	negative selection	7855800
41220852	41220875	22	-	27260156	NCIH1373	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.2641839932807733	[715]	[758,523,877,137]	-3	hSpCas9	negative selection	7977049
41220821	41220844	22	-	27260156	NCIH1373	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.5419262341533504	[313]	[412,67,320,53]	-5	hSpCas9	negative selection	7977051
41220852	41220875	22	-	27260156	PATU8902	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.0867250406060367	[715]	[1102,1047,579,1131]	-1	hSpCas9	negative selection	8098300
41220821	41220844	22	-	27260156	PATU8902	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.19595171160436486	[313]	[494,273,139,715]	-2	hSpCas9	negative selection	8098302
41220852	41220875	22	-	27260156	PANC1	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.4169350006199096	[715]	[819,723,991,730]	6	hSpCas9	negative selection	8219551
41220821	41220844	22	-	27260156	PANC1	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.33565874705589294	[313]	[193,264,175,224]	-5	hSpCas9	negative selection	8219553
41220852	41220875	22	-	27260156	PANC0813	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.15852488799369535	[715]	[1044,621,893,1187]	2	hSpCas9	negative selection	8340802
41220821	41220844	22	-	27260156	PANC0813	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.07268562829038061	[313]	[335,381,506,185]	-1	hSpCas9	negative selection	8340804
41220852	41220875	22	-	27260156	RDES	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.2032002350966754	[715]	[667,607,749,854]	-3	hSpCas9	negative selection	8462053
41220821	41220844	22	-	27260156	RDES	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.40662591749113364	[313]	[193,316,236,357]	-6	hSpCas9	negative selection	8462055
41220852	41220875	22	-	27260156	PC3	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.2612627104136651	[715]	[553,772,1298,1026]	5	hSpCas9	negative selection	8583304
41220821	41220844	22	-	27260156	PC3	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.15749710823067642	[313]	[250,111,366,417]	-4	hSpCas9	negative selection	8583306
41220852	41220875	22	-	27260156	PATU8988T	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.2725964933800268	[715]	[960,787,691,904]	5	hSpCas9	negative selection	8704555
41220821	41220844	22	-	27260156	PATU8988T	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	0.062358392131670826	[313]	[191,302,393,380]	1	hSpCas9	negative selection	8704557
41220852	41220875	22	-	27260156	T47D	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.20016811803370904	[715]	[894,958,967,1011]	4	hSpCas9	negative selection	8825806
41220821	41220844	22	-	27260156	T47D	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.3246730995384165	[313]	[271,238,278,385]	-6	hSpCas9	negative selection	8825808
41220852	41220875	22	-	27260156	SU8686	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.3621247201357138	[715]	[471,485,551,743]	-6	hSpCas9	negative selection	8947057
41220821	41220844	22	-	27260156	SU8686	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.7699547947427159	[313]	[141,145,137,335]	-8	hSpCas9	negative selection	8947059
41220852	41220875	22	-	27260156	SKES1	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.14683439307173118	[715]	[954,848,726,668]	3	hSpCas9	negative selection	9068308
41220821	41220844	22	-	27260156	SKES1	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.3440321292914533	[313]	[172,377,174,262]	-6	hSpCas9	negative selection	9068310
41220852	41220875	22	-	27260156	TOV112D	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	-0.05448203698819254	[715]	[786,704,746,537]	-1	hSpCas9	negative selection	9189559
41220821	41220844	22	-	27260156	TOV112D	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.3551912238123789	[313]	[195,309,220,266]	-6	hSpCas9	negative selection	9189561
41220852	41220875	22	-	27260156	TC71	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.17405919598691189	[715]	[830,794,1008,821]	4	hSpCas9	negative selection	9310810
41220821	41220844	22	-	27260156	TC71	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	0.04753109298661817	[313]	[347,345,372,321]	1	hSpCas9	negative selection	9310812
41220852	41220875	22	-	27260156	TC32	viability	ACTCACTCCGTGGGGGCACTAGG	L3MBTL2	ENSG00000100395	0.04915655162980748	[715]	[527,551,1050,753]	0	hSpCas9	negative selection	9432061
41220821	41220844	22	-	27260156	TC32	viability	GTTGATGGCACACCAGCCAATGG	L3MBTL2	ENSG00000100395	-0.2982438180552103	[313]	[304,194,182,260]	-5	hSpCas9	negative selection	9432063
41205355	41205378	22	+	27869803	HPAFII	viability after 27 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-0.21634933853366434	[44]	[9,28,NaN]	-2	hSpCas9	negative selection	9581057
41219433	41219456	22	-	27869803	HPAFII	viability after 27 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	0.21869740217753753	[221]	[185,93,NaN]	1	hSpCas9	negative selection	9581058
41205355	41205378	22	+	27869803	HPAFII	viability after 15 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-0.1474447113263122	[44]	[18,58,NaN]	-2	hSpCas9	negative selection	9663506
41219433	41219456	22	-	27869803	HPAFII	viability after 15 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	0.5247368988104643	[221]	[370,325,NaN]	6	hSpCas9	negative selection	9663507
41205355	41205378	22	+	27869803	ASPC1	viability after 36 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-0.8942444135283338	[159]	[0,4,69]	-7	hSpCas9	negative selection	9745955
41219433	41219456	22	-	27869803	ASPC1	viability after 36 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	0.07670668654278756	[579]	[75,153,354]	0	hSpCas9	negative selection	9745956
41205355	41205378	22	+	27869803	PATU8988S	viability after 35 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	1.149717335826862	[112]	[89,111,NaN]	9	hSpCas9	negative selection	9828404
41219433	41219456	22	-	27869803	PATU8988S	viability after 35 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	-1.0071026464827677	[491]	[137,58,NaN]	-7	hSpCas9	negative selection	9828405
41205355	41205378	22	+	27869803	PATU8988S	viability after 31 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	0.44925481064652395	[112]	[57,65,NaN]	5	hSpCas9	negative selection	9910853
41219433	41219456	22	-	27869803	PATU8988S	viability after 31 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	-0.4947311243018525	[491]	[85,206,NaN]	-5	hSpCas9	negative selection	9910854
41205355	41205378	22	+	27869803	HPAFII	viability after 35 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-1.678976926810273	[44]	[0,13,NaN]	-7	hSpCas9	negative selection	9993302
41219433	41219456	22	-	27869803	HPAFII	viability after 35 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	0.21288886198405388	[221]	[173,80,NaN]	1	hSpCas9	negative selection	9993303
41205355	41205378	22	+	27869803	HPAFII	viability after 31 days	GAGGTCTCATGGAGAAGCCCCGG	L3MBTL2	ENSG00000100395	-1.0270449661337602	[44]	[9,14,NaN]	-6	hSpCas9	negative selection	10075751
41219433	41219456	22	-	27869803	HPAFII	viability after 31 days	CTTTCATCACATCCTCCCACTGG	L3MBTL2	ENSG00000100395	-0.04473864432246913	[221]	[115,125,NaN]	0	hSpCas9	negative selection	10075752
41227270	41227293	22	-	28162770	P31FUJ	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	-2.1588016229706013	[37]	[9]	-8	hSpCas9	negative selection	10182650
41227219	41227242	22	+	28162770	P31FUJ	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	0.32359114411000667	[220]	[324]	3	hSpCas9	negative selection	10182651
41219448	41219471	22	+	28162770	P31FUJ	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-1.7811062345566866	[271]	[92]	-8	hSpCas9	negative selection	10182652
41220816	41220839	22	-	28162770	P31FUJ	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	0.5556936903919094	[43]	[75]	6	hSpCas9	negative selection	10182653
41224052	41224075	22	+	28162770	P31FUJ	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-1.2877105455167681	[240]	[115]	-7	hSpCas9	negative selection	10182654
41224202	41224225	22	-	28162770	P31FUJ	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	-0.3727324655588534	[118]	[107]	-3	hSpCas9	negative selection	10182655
41225879	41225902	22	-	28162770	P31FUJ	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	-0.44792662528678723	[230]	[198]	-4	hSpCas9	negative selection	10182656
41227149	41227172	22	-	28162770	P31FUJ	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	0.6979351331485077	[63]	[121]	7	hSpCas9	negative selection	10182657
41227270	41227293	22	-	28162770	TF1	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10352016
41227219	41227242	22	+	28162770	TF1	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	NaN	[NaN]	[300]	1	hSpCas9	negative selection	10352017
41219448	41219471	22	+	28162770	TF1	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10352018
41220816	41220839	22	-	28162770	TF1	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10352019
41224052	41224075	22	+	28162770	TF1	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10352020
41224202	41224225	22	-	28162770	TF1	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	NaN	[NaN]	[58]	1	hSpCas9	negative selection	10352021
41225879	41225902	22	-	28162770	TF1	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	NaN	[NaN]	[172]	1	hSpCas9	negative selection	10352022
41227149	41227172	22	-	28162770	TF1	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10352023
41227270	41227293	22	-	28162770	SKM1	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	-2.406964198743162	[2]	[0]	-8	hSpCas9	negative selection	10521382
41227219	41227242	22	+	28162770	SKM1	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	0.6042630566800925	[47]	[128]	6	hSpCas9	negative selection	10521383
41219448	41219471	22	+	28162770	SKM1	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-0.9886515674314568	[54]	[48]	-6	hSpCas9	negative selection	10521384
41220816	41220839	22	-	28162770	SKM1	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	1.690448302914783	[16]	[96]	9	hSpCas9	negative selection	10521385
41224052	41224075	22	+	28162770	SKM1	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-0.8500160741916022	[51]	[50]	-6	hSpCas9	negative selection	10521386
41224202	41224225	22	-	28162770	SKM1	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	-1.0564669516590286	[19]	[16]	-6	hSpCas9	negative selection	10521387
41225879	41225902	22	-	28162770	SKM1	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	-0.1260078849121055	[49]	[80]	-1	hSpCas9	negative selection	10521388
41227149	41227172	22	-	28162770	SKM1	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	0.570315724756755	[23]	[62]	5	hSpCas9	negative selection	10521389
41227270	41227293	22	-	28162770	SKM1	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	-2.406964198743162	[2]	[0]	-8	hSpCas9	negative selection	10690748
41227219	41227242	22	+	28162770	SKM1	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	0.6042630566800925	[47]	[128]	6	hSpCas9	negative selection	10690749
41219448	41219471	22	+	28162770	SKM1	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-0.9886515674314568	[54]	[48]	-6	hSpCas9	negative selection	10690750
41220816	41220839	22	-	28162770	SKM1	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	1.690448302914783	[16]	[96]	9	hSpCas9	negative selection	10690751
41224052	41224075	22	+	28162770	SKM1	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-0.8500160741916022	[51]	[50]	-6	hSpCas9	negative selection	10690752
41224202	41224225	22	-	28162770	SKM1	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	-1.0564669516590286	[19]	[16]	-6	hSpCas9	negative selection	10690753
41225879	41225902	22	-	28162770	SKM1	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	-0.1260078849121055	[49]	[80]	-1	hSpCas9	negative selection	10690754
41227149	41227172	22	-	28162770	SKM1	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	0.570315724756755	[23]	[62]	5	hSpCas9	negative selection	10690755
41227270	41227293	22	-	28162770	PL21	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	1.4564793677491057	[35]	[42]	9	hSpCas9	negative selection	10860114
41227219	41227242	22	+	28162770	PL21	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	1.5109882634961926	[182]	[226]	9	hSpCas9	negative selection	10860115
41219448	41219471	22	+	28162770	PL21	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	0.8673349303513522	[232]	[184]	7	hSpCas9	negative selection	10860116
41220816	41220839	22	-	28162770	PL21	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	0.037868185590443026	[46]	[20]	0	hSpCas9	negative selection	10860117
41224052	41224075	22	+	28162770	PL21	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-1.7246728891164609	[242]	[31]	-8	hSpCas9	negative selection	10860118
41224202	41224225	22	-	28162770	PL21	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	2.270528942380718	[39]	[83]	9	hSpCas9	negative selection	10860119
41225879	41225902	22	-	28162770	PL21	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	-0.05620013877046545	[171]	[71]	0	hSpCas9	negative selection	10860120
41227149	41227172	22	-	28162770	PL21	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	-1.8873232267610194	[50]	[5]	-8	hSpCas9	negative selection	10860121
41227270	41227293	22	-	28162770	P31FUJ	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	-2.1588016229706013	[37]	[9]	-8	hSpCas9	negative selection	11029480
41227219	41227242	22	+	28162770	P31FUJ	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	0.32359114411000667	[220]	[324]	3	hSpCas9	negative selection	11029481
41219448	41219471	22	+	28162770	P31FUJ	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-1.7811062345566866	[271]	[92]	-8	hSpCas9	negative selection	11029482
41220816	41220839	22	-	28162770	P31FUJ	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	0.5556936903919094	[43]	[75]	6	hSpCas9	negative selection	11029483
41224052	41224075	22	+	28162770	P31FUJ	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-1.2877105455167681	[240]	[115]	-7	hSpCas9	negative selection	11029484
41224202	41224225	22	-	28162770	P31FUJ	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	-0.3727324655588534	[118]	[107]	-3	hSpCas9	negative selection	11029485
41225879	41225902	22	-	28162770	P31FUJ	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	-0.44792662528678723	[230]	[198]	-4	hSpCas9	negative selection	11029486
41227149	41227172	22	-	28162770	P31FUJ	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	0.6979351331485077	[63]	[121]	7	hSpCas9	negative selection	11029487
41227270	41227293	22	-	28162770	OCIAML5	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	0.9552883511936066	[5]	[20]	8	hSpCas9	negative selection	11198846
41227219	41227242	22	+	28162770	OCIAML5	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	0.22322155644024028	[139]	[294]	1	hSpCas9	negative selection	11198847
41219448	41219471	22	+	28162770	OCIAML5	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-0.5693363636892834	[96]	[117]	-4	hSpCas9	negative selection	11198848
41220816	41220839	22	-	28162770	OCIAML5	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	0.05482402474452153	[23]	[44]	0	hSpCas9	negative selection	11198849
41224052	41224075	22	+	28162770	OCIAML5	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-1.9143508491183394	[141]	[67]	-7	hSpCas9	negative selection	11198850
41224202	41224225	22	-	28162770	OCIAML5	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	0.20321586463719266	[63]	[132]	1	hSpCas9	negative selection	11198851
41225879	41225902	22	-	28162770	OCIAML5	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	-0.10455105735688092	[108]	[182]	-1	hSpCas9	negative selection	11198852
41227149	41227172	22	-	28162770	OCIAML5	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	0.3958609425795885	[31]	[75]	3	hSpCas9	negative selection	11198853
41227270	41227293	22	-	28162770	EOL1	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	3.126181632740185	[54]	[252]	9	hSpCas9	negative selection	11368212
41227219	41227242	22	+	28162770	EOL1	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	3.9736655381352257	[230]	[1911]	9	hSpCas9	negative selection	11368213
41219448	41219471	22	+	28162770	EOL1	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-0.6701957499432071	[443]	[146]	-5	hSpCas9	negative selection	11368214
41220816	41220839	22	-	28162770	EOL1	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	3.3657043318132605	[64]	[352]	9	hSpCas9	negative selection	11368215
41224052	41224075	22	+	28162770	EOL1	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	0.2879231510268858	[198]	[127]	2	hSpCas9	negative selection	11368216
41224202	41224225	22	-	28162770	EOL1	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	1.8864797307370151	[95]	[186]	9	hSpCas9	negative selection	11368217
41225879	41225902	22	-	28162770	EOL1	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	2.5322303487917743	[272]	[831]	9	hSpCas9	negative selection	11368218
41227149	41227172	22	-	28162770	EOL1	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	2.47834934080523	[77]	[228]	9	hSpCas9	negative selection	11368219
41227270	41227293	22	-	28162770	MOLM13	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	0.00845776290728173	[21]	[15]	0	hSpCas9	negative selection	11537578
41227219	41227242	22	+	28162770	MOLM13	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	1.2529297177146477	[241]	[416]	8	hSpCas9	negative selection	11537579
41219448	41219471	22	+	28162770	MOLM13	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-1.6221957476877389	[412]	[96]	-7	hSpCas9	negative selection	11537580
41220816	41220839	22	-	28162770	MOLM13	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	1.785747812122894	[70]	[176]	9	hSpCas9	negative selection	11537581
41224052	41224075	22	+	28162770	MOLM13	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-1.5255379645319351	[218]	[54]	-6	hSpCas9	negative selection	11537582
41224202	41224225	22	-	28162770	MOLM13	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	-0.3230150197324311	[108]	[62]	-2	hSpCas9	negative selection	11537583
41225879	41225902	22	-	28162770	MOLM13	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	0.4878808567320449	[214]	[217]	3	hSpCas9	negative selection	11537584
41227149	41227172	22	-	28162770	MOLM13	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	-0.07959841375791443	[56]	[38]	0	hSpCas9	negative selection	11537585
41227270	41227293	22	-	28162770	HEL	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	0.3988132491142675	[44]	[37]	3	hSpCas9	negative selection	11706944
41227219	41227242	22	+	28162770	HEL	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	0.36887739568220723	[213]	[176]	3	hSpCas9	negative selection	11706945
41219448	41219471	22	+	28162770	HEL	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-0.9081618326471663	[292]	[99]	-5	hSpCas9	negative selection	11706946
41220816	41220839	22	-	28162770	HEL	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	0.46870943222530803	[43]	[38]	4	hSpCas9	negative selection	11706947
41224052	41224075	22	+	28162770	HEL	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-2.181689603416188	[254]	[35]	-8	hSpCas9	negative selection	11706948
41224202	41224225	22	-	28162770	HEL	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	0.1305326737145147	[86]	[60]	1	hSpCas9	negative selection	11706949
41225879	41225902	22	-	28162770	HEL	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	-0.5399534655158333	[226]	[99]	-4	hSpCas9	negative selection	11706950
41227149	41227172	22	-	28162770	HEL	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	1.266590346115108	[60]	[93]	9	hSpCas9	negative selection	11706951
41227270	41227293	22	-	28162770	MV411	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	1.3178268786741731	[9]	[20]	9	hSpCas9	negative selection	11876310
41227219	41227242	22	+	28162770	MV411	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	1.3559620075609444	[159]	[344]	9	hSpCas9	negative selection	11876311
41219448	41219471	22	+	28162770	MV411	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-0.17537729908778765	[247]	[184]	-1	hSpCas9	negative selection	11876312
41220816	41220839	22	-	28162770	MV411	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	-0.3899923698325165	[69]	[44]	-3	hSpCas9	negative selection	11876313
41224052	41224075	22	+	28162770	MV411	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-3.590505691108252	[142]	[9]	-9	hSpCas9	negative selection	11876314
41224202	41224225	22	-	28162770	MV411	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	0.1985279503018288	[89]	[86]	1	hSpCas9	negative selection	11876315
41225879	41225902	22	-	28162770	MV411	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	-1.2096074750176438	[150]	[54]	-7	hSpCas9	negative selection	11876316
41227149	41227172	22	-	28162770	MV411	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	-0.9541963103868754	[68]	[29]	-6	hSpCas9	negative selection	11876317
41227270	41227293	22	-	28162770	MONOMAC1	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	0.9605044299269263	[12]	[28]	8	hSpCas9	negative selection	12045676
41227219	41227242	22	+	28162770	MONOMAC1	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	1.5090347391608685	[117]	[384]	9	hSpCas9	negative selection	12045677
41219448	41219471	22	+	28162770	MONOMAC1	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-0.24115940029186148	[165]	[160]	-2	hSpCas9	negative selection	12045678
41220816	41220839	22	-	28162770	MONOMAC1	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	1.9368188996752371	[17]	[78]	9	hSpCas9	negative selection	12045679
41224052	41224075	22	+	28162770	MONOMAC1	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	0.7641439040499182	[112]	[219]	7	hSpCas9	negative selection	12045680
41224202	41224225	22	-	28162770	MONOMAC1	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	0.6861494879576964	[44]	[82]	6	hSpCas9	negative selection	12045681
41225879	41225902	22	-	28162770	MONOMAC1	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	0.8391833408531996	[117]	[241]	7	hSpCas9	negative selection	12045682
41227149	41227172	22	-	28162770	MONOMAC1	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	1.5483903258548486	[33]	[113]	9	hSpCas9	negative selection	12045683
41227270	41227293	22	-	28162770	OCIAML2	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	-2.1811232080471763	[8]	[10]	-8	hSpCas9	negative selection	12215042
41227219	41227242	22	+	28162770	OCIAML2	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	-0.33312630149222655	[44]	[197]	-3	hSpCas9	negative selection	12215043
41219448	41219471	22	+	28162770	OCIAML2	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	-1.306243007341279	[28]	[64]	-7	hSpCas9	negative selection	12215044
41220816	41220839	22	-	28162770	OCIAML2	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	-0.5530919854341341	[8]	[33]	-4	hSpCas9	negative selection	12215045
41224052	41224075	22	+	28162770	OCIAML2	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	-2.4262357058837076	[31]	[32]	-8	hSpCas9	negative selection	12215046
41224202	41224225	22	-	28162770	OCIAML2	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	-1.1169928706274606	[17]	[45]	-6	hSpCas9	negative selection	12215047
41225879	41225902	22	-	28162770	OCIAML2	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	-1.3428742780437886	[26]	[58]	-7	hSpCas9	negative selection	12215048
41227149	41227172	22	-	28162770	OCIAML2	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	1.2891070765827033	[10]	[148]	9	hSpCas9	negative selection	12215049
41227270	41227293	22	-	28162770	OCIAML3	viability	GGTGAGCTCACACCAGCCGACGG	L3MBTL2	ENSG00000100395	2.9605812113534746	[1]	[46]	9	hSpCas9	negative selection	12384408
41227219	41227242	22	+	28162770	OCIAML3	viability	GGGACAGCGAGTACGACCAGTGG	L3MBTL2	ENSG00000100395	0.8987611621872467	[69]	[393]	7	hSpCas9	negative selection	12384409
41219448	41219471	22	+	28162770	OCIAML3	viability	GATGAAAGGGATGAAGGTGGAGG	L3MBTL2	ENSG00000100395	0.5869303538405671	[57]	[262]	5	hSpCas9	negative selection	12384410
41220816	41220839	22	-	28162770	OCIAML3	viability	TGGCACACCAGCCAATGGGGTGG	L3MBTL2	ENSG00000100395	0.16498426017204215	[12]	[43]	1	hSpCas9	negative selection	12384411
41224052	41224075	22	+	28162770	OCIAML3	viability	GGGCATGCGGCTGGAAGTGGTGG	L3MBTL2	ENSG00000100395	0.7741434713238448	[42]	[221]	7	hSpCas9	negative selection	12384412
41224202	41224225	22	-	28162770	OCIAML3	viability	GTCGTGACCAACCCACTGGGTGG	L3MBTL2	ENSG00000100395	2.570180991569005	[13]	[250]	9	hSpCas9	negative selection	12384413
41225879	41225902	22	-	28162770	OCIAML3	viability	GGTGGCCGGGAAGATGGCGTGGG	L3MBTL2	ENSG00000100395	1.5369232295022854	[49]	[437]	9	hSpCas9	negative selection	12384414
41227149	41227172	22	-	28162770	OCIAML3	viability	GTGGCCACACAGATGAGCCGGGG	L3MBTL2	ENSG00000100395	1.6283847810122847	[11]	[111]	9	hSpCas9	negative selection	12384415