Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 348801
• Symbol: LNP1
• Description: leukemia NUP98 fusion partner 1

DataSource: http://genomecrispr.dkfz.de/#!/results/LNP1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
100429782	100429805	3	+	26472758	Jiyoye	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.22116339589592446	[123]	[108]	1	hSpCas9	negative selection	91681
100451835	100451858	3	+	26472758	Jiyoye	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	3.107615099646966	[9]	[64]	9	hSpCas9	negative selection	91682
100429792	100429815	3	+	26472758	Jiyoye	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-5.8022779841230765	[73]	[0]	-9	hSpCas9	negative selection	91683
100429851	100429874	3	-	26472758	Jiyoye	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.31746126015101916	[480]	[451]	2	hSpCas9	negative selection	91684
100429810	100429833	3	+	26472758	Jiyoye	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	1.7060198632801944	[62]	[154]	8	hSpCas9	negative selection	91685
100451722	100451745	3	-	26472758	Jiyoye	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.15733490198193456	[282]	[237]	1	hSpCas9	negative selection	91686
100429772	100429795	3	+	26472758	Jiyoye	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.4616231655282501	[51]	[53]	3	hSpCas9	negative selection	91687
100429837	100429860	3	-	26472758	Jiyoye	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	-1.9620584281598457	[216]	[41]	-8	hSpCas9	negative selection	91688
100451851	100451874	3	-	26472758	Jiyoye	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	-0.3655244243935458	[544]	[318]	-3	hSpCas9	negative selection	91689
100429869	100429892	3	-	26472758	Jiyoye	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	-2.2612031274029203	[88]	[13]	-8	hSpCas9	negative selection	91690
100429782	100429805	3	+	26472758	KBM7	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	1.5754550101289015	[485,286]	[841,250]	9	hSpCas9	negative selection	282799
100451835	100451858	3	+	26472758	KBM7	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	0.38300380318607274	[359,286]	[35,340]	4	hSpCas9	negative selection	282800
100429792	100429815	3	+	26472758	KBM7	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-1.8048756747293222	[209,50]	[24,8]	-8	hSpCas9	negative selection	282801
100429851	100429874	3	-	26472758	KBM7	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.35319033668083843	[1585,911]	[749,717]	4	hSpCas9	negative selection	282802
100429810	100429833	3	+	26472758	KBM7	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	0.3989956429204551	[684,476]	[338,369]	4	hSpCas9	negative selection	282803
100451722	100451745	3	-	26472758	KBM7	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.6089686673656751	[947,755]	[702,520]	6	hSpCas9	negative selection	282804
100429772	100429795	3	+	26472758	KBM7	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.6106743751172611	[284,166]	[97,212]	6	hSpCas9	negative selection	282805
100429837	100429860	3	-	26472758	KBM7	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	0.174169119916871	[454,308]	[233,168]	1	hSpCas9	negative selection	282806
100451851	100451874	3	-	26472758	KBM7	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.7601655110874721	[1610,1497]	[1062,1396]	8	hSpCas9	negative selection	282807
100429869	100429892	3	-	26472758	KBM7	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	0.8856005372601978	[232,134]	[122,185]	8	hSpCas9	negative selection	282808
100429782	100429805	3	+	26472758	Raji	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.14248733632951543	[202]	[51]	1	hSpCas9	negative selection	473917
100451835	100451858	3	+	26472758	Raji	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	0.8568400737230024	[137]	[57]	7	hSpCas9	negative selection	473918
100429792	100429815	3	+	26472758	Raji	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-3.6475039667898694	[53]	[0]	-9	hSpCas9	negative selection	473919
100429851	100429874	3	-	26472758	Raji	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.9363057611644883	[625]	[277]	8	hSpCas9	negative selection	473920
100429810	100429833	3	+	26472758	Raji	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	0.13337874390654386	[219]	[55]	1	hSpCas9	negative selection	473921
100451722	100451745	3	-	26472758	Raji	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.3513091182596887	[303]	[89]	3	hSpCas9	negative selection	473922
100429772	100429795	3	+	26472758	Raji	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	-1.2772803148617256	[187]	[17]	-7	hSpCas9	negative selection	473923
100429837	100429860	3	-	26472758	Raji	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	-0.03945785295567161	[154]	[34]	0	hSpCas9	negative selection	473924
100451851	100451874	3	-	26472758	Raji	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.33526961909953457	[1010]	[295]	3	hSpCas9	negative selection	473925
100429869	100429892	3	-	26472758	Raji	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	-0.08330002623551036	[104]	[22]	0	hSpCas9	negative selection	473926
100429782	100429805	3	+	26472758	K562	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.03405886182489623	[397]	[343]	0	hSpCas9	negative selection	665035
100451835	100451858	3	+	26472758	K562	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	1.426622058887196	[129]	[294]	9	hSpCas9	negative selection	665036
100429792	100429815	3	+	26472758	K562	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-0.95113208145136	[212]	[92]	-5	hSpCas9	negative selection	665037
100429851	100429874	3	-	26472758	K562	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.5072460134021333	[1160]	[1392]	4	hSpCas9	negative selection	665038
100429810	100429833	3	+	26472758	K562	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	0.061237629521867676	[368]	[324]	0	hSpCas9	negative selection	665039
100451722	100451745	3	-	26472758	K562	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.7587485924526419	[592]	[846]	6	hSpCas9	negative selection	665040
100429772	100429795	3	+	26472758	K562	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.07919634518942303	[267]	[238]	0	hSpCas9	negative selection	665041
100429837	100429860	3	-	26472758	K562	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	1.6249466965186814	[274]	[715]	9	hSpCas9	negative selection	665042
100451851	100451874	3	-	26472758	K562	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.7899696107145546	[1372]	[2003]	6	hSpCas9	negative selection	665043
100429869	100429892	3	-	26472758	K562	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	1.4538720932953968	[143]	[332]	9	hSpCas9	negative selection	665044
100429878	100429901	3	-	26627737	DLD1	viability	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.6192563438857202	[339]	[39,41,116]	-6	hSpCas9	negative selection	818558
100429878	100429901	3	-	26627737	GBM cells	viability after 5 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	0.28690655115030067	[174]	[141,86]	4	hSpCas9	negative selection	900873
100429878	100429901	3	-	26627737	GBM cells	viability after 13 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	0.044843938827405116	[174]	[135,66]	0	hSpCas9	negative selection	983188
100429878	100429901	3	-	26627737	GBM cells	viability after 21 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	0.11474435236828301	[174]	[115,90]	1	hSpCas9	negative selection	1065503
100429878	100429901	3	-	26627737	RPE1	viability after 9 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-2.1530035484968097	[1371]	[41,166]	-9	hSpCas9	negative selection	1147818
100429878	100429901	3	-	26627737	RPE1	viability after 12 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-3.112204551189403	[1371]	[29,55]	-9	hSpCas9	negative selection	1230133
100429878	100429901	3	-	26627737	RPE1	viability after 15 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-1.6806166618019858	[1371]	[88,151]	-7	hSpCas9	negative selection	1312448
100429878	100429901	3	-	26627737	RPE1	viability after 18 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-2.6815060971746774	[1371]	[63,50]	-9	hSpCas9	negative selection	1394763
100429878	100429901	3	-	26627737	HeLa	viability after 8 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	1.451610661792214	[85]	[86,44,166]	8	hSpCas9	negative selection	1477078
100429878	100429901	3	-	26627737	HeLa	viability after 12 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	0.945607917256384	[85]	[16,85,98]	7	hSpCas9	negative selection	1559393
100429878	100429901	3	-	26627737	HeLa	viability after 15 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	1.098188055288247	[85]	[0,207,11]	7	hSpCas9	negative selection	1641708
100429878	100429901	3	-	26627737	HeLa	viability after 18 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	1.1539508888928407	[85]	[0,178,11]	7	hSpCas9	negative selection	1724023
100429878	100429901	3	-	26627737	HCT116	viability after 6 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-3.242792194503095	[973]	[30,7]	-9	hSpCas9	negative selection	1806338
100429878	100429901	3	-	26627737	HCT116	viability after 8 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	0.5188716889996507	[152]	[102,131,126]	5	hSpCas9	negative selection	1888653
100429878	100429901	3	-	26627737	HCT116	viability after 9 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-2.623062778215844	[973]	[63,24]	-9	hSpCas9	negative selection	1970968
100429878	100429901	3	-	26627737	HCT116	viability after 12 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	0.947099709917263	[152]	[190,158,111]	7	hSpCas9	negative selection	2053283
100429878	100429901	3	-	26627737	HCT116	viability after 15 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	0.8971215497608025	[152]	[136,213,136]	7	hSpCas9	negative selection	2135598
100429878	100429901	3	-	26627737	HCT116	viability after 18 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.09331069603867526	[152]	[39,89,76]	-1	hSpCas9	negative selection	2217913
100434601	100434624	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCTGCCTCCAGG	LNP1	ENSG00000206535	0.3736894149735144	[619,564]	[67,277]	1	dCas9-VP64	positive selection	2444055
100401537	100401560	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGTGGCTATAACTGGAAAACTGG	LNP1	ENSG00000206535	-0.6565577978177697	[21,284]	[24,16]	-3	dCas9-VP64	positive selection	2444959
100401469	100401492	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTATTGGCTAGCAAGGGTGGTGG	LNP1	ENSG00000206535	-2.1750827552346466	[70,73]	[2,3]	-9	dCas9-VP64	positive selection	2444960
100401502	100401525	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GACCGAGCTACCCAGTTTACTGG	LNP1	ENSG00000206535	-1.1429301417720583	[82,145]	[9,11]	-6	dCas9-VP64	positive selection	2444961
100431780	100431803	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCTGGTCTCAAACTCCTTAG	LNP1	ENSG00000206535	1.754298476960665	[131,229]	[162,104]	6	dCas9-VP64	positive selection	2469890
100434601	100434624	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCTGCCTCCAGG	LNP1	ENSG00000206535	2.2699980135687987	[309,268]	[879,61]	8	dCas9-VP64	positive selection	2539310
100401537	100401560	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGTGGCTATAACTGGAAAACTGG	LNP1	ENSG00000206535	-0.4669001491881395	[17,23]	[2,5]	-5	dCas9-VP64	positive selection	2540214
100401469	100401492	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTATTGGCTAGCAAGGGTGGTGG	LNP1	ENSG00000206535	7.170172668171412	[11,19]	[1577,14]	9	dCas9-VP64	positive selection	2540215
100401502	100401525	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GACCGAGCTACCCAGTTTACTGG	LNP1	ENSG00000206535	0.4257511685329941	[76,79]	[42,25]	3	dCas9-VP64	positive selection	2540216
100431780	100431803	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCTGGTCTCAAACTCCTTAG	LNP1	ENSG00000206535	0.3544513964898359	[322,573]	[129,237]	3	dCas9-VP64	positive selection	2565145
100451812	100451835	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATTACAGAAAATACTCAGAGG	LNP1	ENSG00000206535	0.5838605732042152	[2,3]	[3,4]	9	hSpCas9	positive selection	2999754
100429877	100429900	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGACAATCACTCACTGGGCAGGG	LNP1	ENSG00000206535	0.20578802981836689	[3,3]	[2,4]	4	hSpCas9	positive selection	2999755
100429803	100429826	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGGAGAGAGGAGGATCAGAGAGG	LNP1	ENSG00000206535	-0.21471649684499783	[5,5]	[3,3]	-3	hSpCas9	positive selection	2999756
100451796	100451819	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	0.5284672763108698	[4,4]	[5,6]	9	hSpCas9	positive selection	2999757
100451812	100451835	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATTACAGAAAATACTCAGAGG	LNP1	ENSG00000206535	0.3419079402894041	[2,2]	[2,2]	6	hSpCas9	positive selection	3067612
100429877	100429900	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGACAATCACTCACTGGGCAGGG	LNP1	ENSG00000206535	0.6509855901385536	[3,3]	[5,3]	9	hSpCas9	positive selection	3067613
100429803	100429826	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGGAGAGAGGAGGATCAGAGAGG	LNP1	ENSG00000206535	0.3691327906353758	[5,5]	[5,4]	6	hSpCas9	positive selection	3067614
100451796	100451819	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	-0.027120796652679025	[4,4]	[3,2]	0	hSpCas9	positive selection	3067615
100429770	100429793		-	24336571	A375	resistance to PLX after 7 days	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	-0.22562267029265354	[21,19]	[17,16]	-7	hSpCas9	positive selection	3124941
100451789	100451812		+	24336571	A375	resistance to PLX after 7 days	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.11568581670904776	[27,23]	[27,28]	4	hSpCas9	positive selection	3124942
100429770	100429793		-	24336571	A375	resistance to PLX after 14 days	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	-0.872569376223014	[24,21]	[5,4]	-8	hSpCas9	positive selection	3182734
100451789	100451812		+	24336571	A375	resistance to PLX after 14 days	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	-0.730318056160765	[29,29]	[7,8]	-8	hSpCas9	positive selection	3182735
100429770	100429793		-	24336571	A375	viability after 7 days	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.3504825372251484	[16]	[21,19]	5	hSpCas9	negative selection	3240527
100451789	100451812		+	24336571	A375	viability after 7 days	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.4428726452242694	[19]	[27,23]	6	hSpCas9	negative selection	3240528
100429770	100429793		-	24336571	A375	viability after 14 days	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.5281862625991016	[16]	[24,21]	6	hSpCas9	negative selection	3298320
100451789	100451812		+	24336571	A375	viability after 14 days	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.6370682724118498	[19]	[29,29]	7	hSpCas9	negative selection	3298321
100455894	100455917	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	1.4244361972810935	[56,56]	[0,0]	6	hSpCas9	positive selection	3377366
100429840	100429863	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.16893854325626279	[171,171]	[0,0]	-1	hSpCas9	positive selection	3377367
100455861	100455884	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	5.257326211445835	[3,3]	[0,0]	9	hSpCas9	positive selection	3377368
100451811	100451834	3	+	26780180	HT29	viability (Avana library 4 designs)	GGATTACAGAAAATACTCAGAGG	LNP1	ENSG00000206535	0.887519852493763	[]	[]	3	hSpCas9	negative selection	3437315
100429877	100429900	3	-	26780180	HT29	viability (Avana library 4 designs)	TGACAATCACTCACTGGGCAGGG	LNP1	ENSG00000206535	1.59186055973188	[]	[]	6	hSpCas9	negative selection	3437316
100429802	100429825	3	+	26780180	HT29	viability (Avana library 4 designs)	TGGAGAGAGGAGGATCAGAGAGG	LNP1	ENSG00000206535	1.32119493996875	[]	[]	5	hSpCas9	negative selection	3437317
100451796	100451819	3	-	26780180	HT29	viability (Avana library 4 designs)	TGTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	1.42599453812138	[]	[]	5	hSpCas9	negative selection	3437318
100451811	100451834	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATTACAGAAAATACTCAGAGG	LNP1	ENSG00000206535	-9.56714242759656	[]	[]	-7	hSpCas9	negative selection	3525970
100429877	100429900	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGACAATCACTCACTGGGCAGGG	LNP1	ENSG00000206535	1.83942509293075	[]	[]	2	hSpCas9	negative selection	3525971
100429802	100429825	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGAGAGAGGAGGATCAGAGAGG	LNP1	ENSG00000206535	1.07674720519896	[]	[]	1	hSpCas9	negative selection	3525972
100451796	100451819	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	2.38761309340731	[]	[]	3	hSpCas9	negative selection	3525973
100429795	100429818	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATCCTCCTCTCTCCAGCTGTGG	LNP1	ENSG00000206535	0.650950557085449	[]	[]	0	hSpCas9	negative selection	3525974
100429770	100429793	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	5.48852871013005	[]	[]	8	hSpCas9	negative selection	3525975
100451811	100451834	3	+	26780180	A375	viability (Avana lentiGuide)	GGATTACAGAAAATACTCAGAGG	LNP1	ENSG00000206535	-9.2381164125596	[]	[]	-9	hSpCas9	negative selection	3634629
100429877	100429900	3	-	26780180	A375	viability (Avana lentiGuide)	TGACAATCACTCACTGGGCAGGG	LNP1	ENSG00000206535	1.31038889428828	[]	[]	1	hSpCas9	negative selection	3634630
100429802	100429825	3	+	26780180	A375	viability (Avana lentiGuide)	TGGAGAGAGGAGGATCAGAGAGG	LNP1	ENSG00000206535	3.13972859333592	[]	[]	3	hSpCas9	negative selection	3634631
100451796	100451819	3	-	26780180	A375	viability (Avana lentiGuide)	TGTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	0.788700738728006	[]	[]	1	hSpCas9	negative selection	3634632
100429795	100429818	3	-	26780180	A375	viability (Avana lentiGuide)	GATCCTCCTCTCTCCAGCTGTGG	LNP1	ENSG00000206535	6.55747798176634	[]	[]	5	hSpCas9	negative selection	3634633
100429770	100429793	3	-	26780180	A375	viability (Avana lentiGuide)	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	-6.43825718756611	[]	[]	-9	hSpCas9	negative selection	3634634
100451811	100451834	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATTACAGAAAATACTCAGAGG	LNP1	ENSG00000206535	-1.0702835078974238	[6]	[1,3]	-9	hSpCas9	positive selection	3743288
100429877	100429900	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGACAATCACTCACTGGGCAGGG	LNP1	ENSG00000206535	-0.013951153085271149	[4]	[5,3]	0	hSpCas9	positive selection	3743289
100429802	100429825	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGAGAGAGGAGGATCAGAGAGG	LNP1	ENSG00000206535	0.21821076879663842	[6]	[7,8]	6	hSpCas9	positive selection	3743290
100451796	100451819	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	0.17213765382738638	[6]	[7,7]	5	hSpCas9	positive selection	3743291
100429795	100429818	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCCTCCTCTCTCCAGCTGTGG	LNP1	ENSG00000206535	-0.013849499212701427	[5]	[4,5]	0	hSpCas9	positive selection	3743292
100429770	100429793	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.32455974267487275	[4]	[5,5]	8	hSpCas9	positive selection	3743293
100451811	100451834	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATTACAGAAAATACTCAGAGG	LNP1	ENSG00000206535	0.36782687874816955	[4]	[4,6]	9	hSpCas9	positive selection	3851895
100429877	100429900	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGACAATCACTCACTGGGCAGGG	LNP1	ENSG00000206535	-0.7220911278080857	[5]	[2,2]	-7	hSpCas9	positive selection	3851896
100429802	100429825	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGAGAGAGGAGGATCAGAGAGG	LNP1	ENSG00000206535	0.058404761833667274	[7]	[6,6]	1	hSpCas9	positive selection	3851897
100451796	100451819	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	0.18143605282378272	[6]	[6,6]	4	hSpCas9	positive selection	3851898
100429795	100429818	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCCTCCTCTCTCCAGCTGTGG	LNP1	ENSG00000206535	-0.06637912924218511	[6]	[5,4]	-1	hSpCas9	positive selection	3851899
100429770	100429793	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.3465378302484269	[6]	[7,6]	8	hSpCas9	positive selection	3851900
100451903	100451926	3	-	26780180	A375	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	1.03483069728212	[]	[]	5	hSpCas9	negative selection	3957543
100455861	100455884	3	+	26780180	A375	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-0.0106141350372599	[]	[]	0	hSpCas9	negative selection	3957544
100455894	100455917	3	+	26780180	A375	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.238437294345934	[]	[]	0	hSpCas9	negative selection	3957545
100429770	100429793	3	-	26780180	A375	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	-0.00212172289682395	[]	[]	0	hSpCas9	negative selection	3957546
100429840	100429863	3	-	26780180	A375	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	1.47698220030077	[]	[]	8	hSpCas9	negative selection	3957547
100451789	100451812	3	+	26780180	A375	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.727416277694827	[]	[]	2	hSpCas9	negative selection	3957548
100451903	100451926	3	-	26780180	HT29	viability (GeCKOv2 library)	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	1.4875798880192	[]	[]	7	hSpCas9	negative selection	4065509
100455861	100455884	3	+	26780180	HT29	viability (GeCKOv2 library)	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.194179624628406	[]	[]	0	hSpCas9	negative selection	4065510
100455894	100455917	3	+	26780180	HT29	viability (GeCKOv2 library)	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.861035590687103	[]	[]	3	hSpCas9	negative selection	4065511
100429770	100429793	3	-	26780180	HT29	viability (GeCKOv2 library)	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	-0.806119208498235	[]	[]	-9	hSpCas9	negative selection	4065512
100429840	100429863	3	-	26780180	HT29	viability (GeCKOv2 library)	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	1.52418256843041	[]	[]	7	hSpCas9	negative selection	4065513
100451789	100451812	3	+	26780180	HT29	viability (GeCKOv2 library)	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	1.96681965857892	[]	[]	9	hSpCas9	negative selection	4065514
100429770	100429793	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	-0.013766638926931363	[4]	[3,2]	0	hSpCas9	positive selection	4149029
100451789	100451812	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.04864375873440557	[4]	[3,2]	1	hSpCas9	positive selection	4149030
100429770	100429793	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.3397584335074953	[3]	[2,3,2,0]	2	hSpCas9	positive selection	4213051
100451789	100451812	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.9724114868716003	[4]	[4,5,1,3]	6	hSpCas9	positive selection	4213052
100451789	100451812	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.17835400975345922	[2]	[2,1]	3	hSpCas9	positive selection	4280402
100451903	100451926	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.23056453332965093	[2]	[1,2]	4	hSpCas9	positive selection	4280403
100429770	100429793	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.43846994122075134	[3]	[4,3]	8	hSpCas9	positive selection	4280404
100455894	100455917	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.39509878068392656	[1]	[2,1]	7	hSpCas9	positive selection	4344662
100429840	100429863	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	0.2040877320533042	[3]	[3,3]	4	hSpCas9	positive selection	4344663
100455861	100455884	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.720734658648477	[0]	[1,0]	9	hSpCas9	positive selection	4344664
100429828	100429850	3	-	27760321	OCIAML3	viability	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	0.2929626687238802	[1161,970]	[824,1268]	3	hSpCas9	negative selection	4414817
100429878	100429900	3	-	27760321	OCIAML3	viability	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.6725179893145008	[662,531]	[284,299]	-6	hSpCas9	negative selection	4414818
100451745	100451767	3	+	27760321	OCIAML3	viability	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	0.7192144462996553	[522,450]	[557,712]	8	hSpCas9	negative selection	4414819
100451796	100451818	3	-	27760321	OCIAML3	viability	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	-0.2609810311262728	[706,588]	[464,363]	-3	hSpCas9	negative selection	4414820
100451846	100451868	3	+	27760321	OCIAML3	viability	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	-0.1576122857100608	[168,132]	[56,167]	-2	hSpCas9	negative selection	4414821
100429828	100429850	3	-	27760321	OCIAML2	viability	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	0.4115333017216245	[1161,970]	[971,1367]	5	hSpCas9	negative selection	4498280
100429878	100429900	3	-	27760321	OCIAML2	viability	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	0.004254443645659467	[662,531]	[396,593]	0	hSpCas9	negative selection	4498281
100451745	100451767	3	+	27760321	OCIAML2	viability	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	0.23415873493395117	[522,450]	[405,535]	3	hSpCas9	negative selection	4498282
100451796	100451818	3	-	27760321	OCIAML2	viability	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	0.5607690057297018	[706,588]	[728,823]	7	hSpCas9	negative selection	4498283
100451846	100451868	3	+	27760321	OCIAML2	viability	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	0.6522499016729562	[168,132]	[125,275]	8	hSpCas9	negative selection	4498284
100429828	100429850	3	-	27760321	MV411	viability	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	0.29515414301055354	[1161,970]	[911,781]	2	hSpCas9	negative selection	4581743
100429878	100429900	3	-	27760321	MV411	viability	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.07541930689317461	[662,531]	[455,245]	0	hSpCas9	negative selection	4581744
100451745	100451767	3	+	27760321	MV411	viability	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	0.8454447219138401	[522,450]	[622,504]	6	hSpCas9	negative selection	4581745
100451796	100451818	3	-	27760321	MV411	viability	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	0.024600976627458082	[706,588]	[369,527]	0	hSpCas9	negative selection	4581746
100451846	100451868	3	+	27760321	MV411	viability	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	0.017169239676614545	[168,132]	[78,131]	0	hSpCas9	negative selection	4581747
100429828	100429850	3	-	27760321	HL60	viability	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	0.7953645180852267	[1161,970]	[1549,1458]	8	hSpCas9	negative selection	4665206
100429878	100429900	3	-	27760321	HL60	viability	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.04067653495507839	[662,531]	[398,548]	0	hSpCas9	negative selection	4665207
100451745	100451767	3	+	27760321	HL60	viability	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	0.12846279051855547	[522,450]	[471,392]	1	hSpCas9	negative selection	4665208
100451796	100451818	3	-	27760321	HL60	viability	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	-0.17517074969097335	[706,588]	[494,436]	-2	hSpCas9	negative selection	4665209
100451846	100451868	3	+	27760321	HL60	viability	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	0.8062254881137128	[168,132]	[256,168]	8	hSpCas9	negative selection	4665210
100429828	100429850	3	-	27760321	HT1080	viability	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	-0.3483752930361499	[970,757]	[333,200]	-2	hSpCas9	negative selection	4748669
100429878	100429900	3	-	27760321	HT1080	viability	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.3758836699197028	[531,414]	[173,113]	-2	hSpCas9	negative selection	4748670
100451745	100451767	3	+	27760321	HT1080	viability	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	0.628125568957841	[450,351]	[103,403]	3	hSpCas9	negative selection	4748671
100451796	100451818	3	-	27760321	HT1080	viability	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	0.7137916645054563	[588,459]	[325,360]	4	hSpCas9	negative selection	4748672
100451846	100451868	3	+	27760321	HT1080	viability	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	0.9906551246569156	[132,103]	[110,74]	5	hSpCas9	negative selection	4748673
100429828	100429850	3	-	27760321	HT29	viability after 7 days	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	0.060396325538953466	[970,757]	[1128,1146,1193]	0	hSpCas9	negative selection	4832132
100429878	100429900	3	-	27760321	HT29	viability after 7 days	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	0.05557368048141481	[531,414]	[829,454,639]	0	hSpCas9	negative selection	4832133
100451745	100451767	3	+	27760321	HT29	viability after 7 days	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	0.44406998973698564	[450,351]	[659,648,787]	6	hSpCas9	negative selection	4832134
100451796	100451818	3	-	27760321	HT29	viability after 7 days	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	-0.2606952223328665	[588,459]	[543,635,506]	-4	hSpCas9	negative selection	4832135
100451846	100451868	3	+	27760321	HT29	viability after 7 days	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	0.9224069398632108	[132,103]	[366,344,168]	9	hSpCas9	negative selection	4832136
100429828	100429850	3	-	27760321	HT29	viability after 25 days	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	-0.012344882001197988	[970,757]	[998,965,969]	0	hSpCas9	negative selection	4915595
100429878	100429900	3	-	27760321	HT29	viability after 25 days	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.12079922113659641	[531,414]	[459,670,347]	-1	hSpCas9	negative selection	4915596
100451745	100451767	3	+	27760321	HT29	viability after 25 days	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	0.19178297622307403	[450,351]	[289,678,627]	2	hSpCas9	negative selection	4915597
100451796	100451818	3	-	27760321	HT29	viability after 25 days	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	-0.12918281139062515	[588,459]	[618,488,528]	-1	hSpCas9	negative selection	4915598
100451846	100451868	3	+	27760321	HT29	viability after 25 days	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	0.6951131702533379	[132,103]	[202,214,242]	7	hSpCas9	negative selection	4915599
100429828	100429850	3	-	27760321	HT29	viability after 22 days	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	0.08927228259314512	[970,757]	[992,1082,1115]	0	hSpCas9	negative selection	4999058
100429878	100429900	3	-	27760321	HT29	viability after 22 days	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.18443419832729427	[531,414]	[521,538,381]	-2	hSpCas9	negative selection	4999059
100451745	100451767	3	+	27760321	HT29	viability after 22 days	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	0.34509104464936713	[450,351]	[515,739,513]	3	hSpCas9	negative selection	4999060
100451796	100451818	3	-	27760321	HT29	viability after 22 days	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	-0.2918834082698866	[588,459]	[403,522,561]	-3	hSpCas9	negative selection	4999061
100451846	100451868	3	+	27760321	HT29	viability after 22 days	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	0.963132451394288	[132,103]	[98,422,283]	9	hSpCas9	negative selection	4999062
100429828	100429850	3	-	27760321	HT29	viability after 19 days	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	0.20729976228682467	[970,757]	[1258,1382,806]	2	hSpCas9	negative selection	5082521
100429878	100429900	3	-	27760321	HT29	viability after 19 days	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	0.2510711739781576	[531,414]	[659,561,709]	2	hSpCas9	negative selection	5082522
100451745	100451767	3	+	27760321	HT29	viability after 19 days	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	0.14454673897043127	[450,351]	[506,766,257]	1	hSpCas9	negative selection	5082523
100451796	100451818	3	-	27760321	HT29	viability after 19 days	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	0.05057842115258715	[588,459]	[624,648,590]	0	hSpCas9	negative selection	5082524
100451846	100451868	3	+	27760321	HT29	viability after 19 days	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	0.4990733223718864	[132,103]	[252,109,216]	5	hSpCas9	negative selection	5082525
100429828	100429850	3	-	27760321	HT29	viability after 16 days	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	-0.14909631088062558	[970,757]	[869,772,975]	-1	hSpCas9	negative selection	5165984
100429878	100429900	3	-	27760321	HT29	viability after 16 days	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.2908760823204337	[531,414]	[568,463,277]	-3	hSpCas9	negative selection	5165985
100451745	100451767	3	+	27760321	HT29	viability after 16 days	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	0.37347064151418763	[450,351]	[266,808,633]	4	hSpCas9	negative selection	5165986
100451796	100451818	3	-	27760321	HT29	viability after 16 days	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	-0.2361625932768232	[588,459]	[468,376,648]	-3	hSpCas9	negative selection	5165987
100451846	100451868	3	+	27760321	HT29	viability after 16 days	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	0.8185445911107104	[132,103]	[134,354,198]	8	hSpCas9	negative selection	5165988
100429828	100429850	3	-	27760321	HT29	viability after 13 days	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	0.17202619815446862	[970,757]	[1439,1127,838]	2	hSpCas9	negative selection	5249447
100429878	100429900	3	-	27760321	HT29	viability after 13 days	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.04555201931400038	[531,414]	[452,683,463]	0	hSpCas9	negative selection	5249448
100451745	100451767	3	+	27760321	HT29	viability after 13 days	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	0.5145286406081533	[450,351]	[656,723,617]	6	hSpCas9	negative selection	5249449
100451796	100451818	3	-	27760321	HT29	viability after 13 days	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	0.05579542437091223	[588,459]	[470,542,868]	0	hSpCas9	negative selection	5249450
100451846	100451868	3	+	27760321	HT29	viability after 13 days	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	0.8290734305503943	[132,103]	[162,241,322]	9	hSpCas9	negative selection	5249451
100429828	100429850	3	-	27760321	HT29	viability after 10 days	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	-0.13490654187544382	[970,757]	[1124,1000,826]	-2	hSpCas9	negative selection	5332910
100429878	100429900	3	-	27760321	HT29	viability after 10 days	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.12712335718590873	[531,414]	[765,463,394]	-2	hSpCas9	negative selection	5332911
100451745	100451767	3	+	27760321	HT29	viability after 10 days	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	0.16414795035180732	[450,351]	[648,401,627]	2	hSpCas9	negative selection	5332912
100451796	100451818	3	-	27760321	HT29	viability after 10 days	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	0.10842446215240253	[588,459]	[725,758,635]	1	hSpCas9	negative selection	5332913
100451846	100451868	3	+	27760321	HT29	viability after 10 days	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	0.7465167170406659	[132,103]	[258,308,179]	8	hSpCas9	negative selection	5332914
100429828	100429850	3	-	27760321	MOLM13	viability	TTGCAGTCGGTGGCGTTCCCGG	LNP1	ENSG00000206535	0.4283795106785544	[1161,970]	[517,1051]	3	hSpCas9	negative selection	5416373
100429878	100429900	3	-	27760321	MOLM13	viability	TGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	0.29761067868444246	[662,531]	[640,216]	2	hSpCas9	negative selection	5416374
100451745	100451767	3	+	27760321	MOLM13	viability	ATCTGACTGCCATCCTAGAAGG	LNP1	ENSG00000206535	1.0237470431689006	[522,450]	[723,414]	7	hSpCas9	negative selection	5416375
100451796	100451818	3	-	27760321	MOLM13	viability	GTAATCCCGTACGTGGCTACGG	LNP1	ENSG00000206535	0.3399938639791946	[706,588]	[469,452]	2	hSpCas9	negative selection	5416376
100451846	100451868	3	+	27760321	MOLM13	viability	AGGAGCCACTGGAATCAAAAGG	LNP1	ENSG00000206535	3.010776135442601	[168,132]	[840,546]	9	hSpCas9	negative selection	5416377
100401388	100401411	3	+	27661255	K562	viability	GGGCGCTCAAGAGATCCGAGTGG	LNP1	ENSG00000206535	0.07564247967135795	[1777,2173]	[1773,1557]	2	dCas9-KRAB	negative selection	5490598
100401740	100401763	3	+	27661255	K562	viability	GGTTATAGGGGAGATAGCGATGG	LNP1	ENSG00000206535	-0.06987167825168328	[888,1131]	[823,715]	-3	dCas9-KRAB	negative selection	5490599
100401388	100401411	3	+	27661255	K562	viability	GGGCGCTCAAGAGATCCGAGTGG	LNP1	ENSG00000206535	0.07564247967135795	[1777,2173]	[1773,1557]	2	dCas9-KRAB	negative selection	5519098
100451789	100451812	3	+	27260156	BXPC3	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	-0.05143829376941883	[360]	[323,340,401,397]	-1	hSpCas9	negative selection	5552862
100451903	100451926	3	-	27260156	BXPC3	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.07535636749202534	[363]	[269,298,281,637]	-2	hSpCas9	negative selection	5552863
100429770	100429793	3	-	27260156	BXPC3	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.5695060076791493	[881]	[1137,1336,1411,1638]	9	hSpCas9	negative selection	5552864
100455894	100455917	3	+	27260156	BXPC3	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.2765142295315104	[169]	[132,203,254,286]	6	hSpCas9	negative selection	5617122
100429840	100429863	3	-	27260156	BXPC3	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.0504939141068651	[738]	[646,772,672,914]	-1	hSpCas9	negative selection	5617123
100455861	100455884	3	+	27260156	BXPC3	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.018385443925646783	[11]	[19,21,2,2]	0	hSpCas9	negative selection	5617124
100451789	100451812	3	+	27260156	A673	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	-0.18202241908428324	[360]	[364,304,412,447]	-4	hSpCas9	negative selection	5674113
100451903	100451926	3	-	27260156	A673	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.05708507455145567	[363]	[430,402,342,509]	-1	hSpCas9	negative selection	5674114
100429770	100429793	3	-	27260156	A673	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.7240968040855594	[881]	[1802,1709,1700,1789]	9	hSpCas9	negative selection	5674115
100455894	100455917	3	+	27260156	A673	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.14888400795475043	[169]	[218,264,181,237]	3	hSpCas9	negative selection	5738373
100429840	100429863	3	-	27260156	A673	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.11653260722009828	[738]	[859,639,953,826]	-3	hSpCas9	negative selection	5738374
100455861	100455884	3	+	27260156	A673	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.04037599424320604	[11]	[24,0,15,18]	0	hSpCas9	negative selection	5738375
100451789	100451812	3	+	27260156	A375	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.23025906852625513	[360]	[519,592,323,546]	3	hSpCas9	negative selection	5795364
100451903	100451926	3	-	27260156	A375	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.13283540216354164	[363]	[248,441,424,711]	2	hSpCas9	negative selection	5795365
100429770	100429793	3	-	27260156	A375	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.7859154405950323	[881]	[1593,2031,1996,1537]	9	hSpCas9	negative selection	5795366
100455894	100455917	3	+	27260156	A375	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.7975683105266825	[169]	[326,525,342,222]	9	hSpCas9	negative selection	5859624
100429840	100429863	3	-	27260156	A375	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	0.10518608109057015	[738]	[1020,921,848,918]	1	hSpCas9	negative selection	5859625
100455861	100455884	3	+	27260156	A375	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-1.4156882068874879	[11]	[0,8,10,0]	-9	hSpCas9	negative selection	5859626
100451789	100451812	3	+	27260156	COLO741	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	-0.07843547661558425	[360]	[410,411,480]	-2	hSpCas9	negative selection	5916615
100451903	100451926	3	-	27260156	COLO741	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.05414616225286695	[363]	[584,443,333]	-1	hSpCas9	negative selection	5916616
100429770	100429793	3	-	27260156	COLO741	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.6150303776442042	[881]	[1676,1737,1752]	9	hSpCas9	negative selection	5916617
100455894	100455917	3	+	27260156	COLO741	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.4816633503989669	[169]	[341,302,269]	8	hSpCas9	negative selection	5980875
100429840	100429863	3	-	27260156	COLO741	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.49459052908298706	[738]	[910,573,552]	-8	hSpCas9	negative selection	5980876
100455861	100455884	3	+	27260156	COLO741	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-1.4774348072524788	[11]	[10,0,4]	-9	hSpCas9	negative selection	5980877
100451789	100451812	3	+	27260156	CAL120	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.3605938829155627	[360]	[647,469,621]	5	hSpCas9	negative selection	6037866
100451903	100451926	3	-	27260156	CAL120	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.7235978533685656	[363]	[927,612,729]	9	hSpCas9	negative selection	6037867
100429770	100429793	3	-	27260156	CAL120	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.9024763574972713	[881]	[2308,2070,1816]	9	hSpCas9	negative selection	6037868
100455894	100455917	3	+	27260156	CAL120	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.28174604964286787	[169]	[184,343,231]	4	hSpCas9	negative selection	6102126
100429840	100429863	3	-	27260156	CAL120	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.21326087018823342	[738]	[738,770,859]	-3	hSpCas9	negative selection	6102127
100455861	100455884	3	+	27260156	CAL120	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-1.6063530979383662	[11]	[12,1,0]	-9	hSpCas9	negative selection	6102128
100451789	100451812	3	+	27260156	CADOES1	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.21279686285018898	[360]	[409,329,382,434]	3	hSpCas9	negative selection	6159117
100451903	100451926	3	-	27260156	CADOES1	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.0536760586918309	[363]	[458,399,305,235]	0	hSpCas9	negative selection	6159118
100429770	100429793	3	-	27260156	CADOES1	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.7803703164592425	[881]	[1390,1503,1281,1460]	9	hSpCas9	negative selection	6159119
100455894	100455917	3	+	27260156	CADOES1	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	-0.0830530105348033	[169]	[192,138,113,150]	-1	hSpCas9	negative selection	6223377
100429840	100429863	3	-	27260156	CADOES1	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.4836507975847981	[738]	[488,426,711,331]	-7	hSpCas9	negative selection	6223378
100455861	100455884	3	+	27260156	CADOES1	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.6619012370983288	[11]	[13,3,24,27]	9	hSpCas9	negative selection	6223379
100451789	100451812	3	+	27260156	EWS502	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	-0.18442528288276822	[360]	[319,329,331,366]	-3	hSpCas9	negative selection	6280368
100451903	100451926	3	-	27260156	EWS502	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.14068441773746865	[363]	[328,295,497,275]	-3	hSpCas9	negative selection	6280369
100429770	100429793	3	-	27260156	EWS502	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.9320220238763047	[881]	[1634,1678,1995,1841]	9	hSpCas9	negative selection	6280370
100455894	100455917	3	+	27260156	EWS502	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.05398618152656498	[169]	[126,252,192,177]	0	hSpCas9	negative selection	6344628
100429840	100429863	3	-	27260156	EWS502	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.3510621999019828	[738]	[455,620,693,707]	-6	hSpCas9	negative selection	6344629
100455861	100455884	3	+	27260156	EWS502	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-0.19316546945377322	[11]	[25,1,1,12]	-3	hSpCas9	negative selection	6344630
100451789	100451812	3	+	27260156	EW8	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.0817036083256284	[360]	[338,381,251,277]	1	hSpCas9	negative selection	6401619
100451903	100451926	3	-	27260156	EW8	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.14170501361784515	[363]	[254,250,268,291]	-3	hSpCas9	negative selection	6401620
100429770	100429793	3	-	27260156	EW8	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.738227461434147	[881]	[1622,1264,850,1132]	9	hSpCas9	negative selection	6401621
100455894	100455917	3	+	27260156	EW8	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.5070226408231941	[169]	[307,232,132,131]	8	hSpCas9	negative selection	6465879
100429840	100429863	3	-	27260156	EW8	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.24355506757068796	[738]	[511,550,493,467]	-4	hSpCas9	negative selection	6465880
100455861	100455884	3	+	27260156	EW8	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.008300829976880308	[11]	[31,0,0,8]	0	hSpCas9	negative selection	6465881
100451789	100451812	3	+	27260156	CORL105	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.21182049811136253	[360]	[497,533,543,389]	4	hSpCas9	negative selection	6522870
100451903	100451926	3	-	27260156	CORL105	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.1781945020241673	[363]	[478,345,421,270]	-3	hSpCas9	negative selection	6522871
100429770	100429793	3	-	27260156	CORL105	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.7544993652307709	[881]	[1804,1709,1928,1555]	9	hSpCas9	negative selection	6522872
100455894	100455917	3	+	27260156	CORL105	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.30756439685544845	[169]	[246,193,308,245]	6	hSpCas9	negative selection	6587130
100429840	100429863	3	-	27260156	CORL105	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.024303290832638158	[738]	[701,764,1112,859]	0	hSpCas9	negative selection	6587131
100455861	100455884	3	+	27260156	CORL105	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	1.1482987152765771	[11]	[35,37,45,6]	9	hSpCas9	negative selection	6587132
100451789	100451812	3	+	27260156	HS294T	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.3721672554434591	[360]	[265,134,129,184]	5	hSpCas9	negative selection	6644121
100451903	100451926	3	-	27260156	HS294T	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.10887173372616021	[363]	[127,113,141,139]	-1	hSpCas9	negative selection	6644122
100429770	100429793	3	-	27260156	HS294T	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.8131910634545226	[881]	[591,758,479,550]	9	hSpCas9	negative selection	6644123
100455894	100455917	3	+	27260156	HS294T	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.36208659141951904	[169]	[106,70,82,72]	5	hSpCas9	negative selection	6708381
100429840	100429863	3	-	27260156	HS294T	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	0.26018683594961944	[738]	[275,344,300,473]	3	hSpCas9	negative selection	6708382
100455861	100455884	3	+	27260156	HS294T	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-0.17721543861901345	[11]	[3,0,4,6]	-2	hSpCas9	negative selection	6708383
100451789	100451812	3	+	27260156	HCC44	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	-0.3145011648075586	[360]	[311,179,456,400]	-5	hSpCas9	negative selection	6765372
100451903	100451926	3	-	27260156	HCC44	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.15562472956991188	[363]	[400,681,342,350]	2	hSpCas9	negative selection	6765373
100429770	100429793	3	-	27260156	HCC44	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.7244308161285066	[881]	[1198,1919,2041,1413]	9	hSpCas9	negative selection	6765374
100455894	100455917	3	+	27260156	HCC44	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.7852732119984372	[169]	[276,250,392,415]	9	hSpCas9	negative selection	6829632
100429840	100429863	3	-	27260156	HCC44	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.0520001275781915	[738]	[609,766,1107,773]	-1	hSpCas9	negative selection	6829633
100455861	100455884	3	+	27260156	HCC44	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.30611078898629973	[11]	[20,38,0,0]	5	hSpCas9	negative selection	6829634
100451789	100451812	3	+	27260156	G402	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.4734444780596123	[360]	[866,763,464,403]	6	hSpCas9	negative selection	6886623
100451903	100451926	3	-	27260156	G402	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.14719562979956693	[363]	[568,685,241,490]	1	hSpCas9	negative selection	6886624
100429770	100429793	3	-	27260156	G402	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.8032686575942204	[881]	[2156,1923,1845,1632]	8	hSpCas9	negative selection	6886625
100455894	100455917	3	+	27260156	G402	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.3047805200978013	[169]	[110,227,335,322]	4	hSpCas9	negative selection	6950883
100429840	100429863	3	-	27260156	G402	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	0.23811121617165731	[738]	[988,1005,1284,960]	3	hSpCas9	negative selection	6950884
100455861	100455884	3	+	27260156	G402	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-0.3599480209940271	[11]	[0,0,40,0]	-4	hSpCas9	negative selection	6950885
100451789	100451812	3	+	27260156	L33	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.36657592521016463	[360]	[486,176,276,500]	7	hSpCas9	negative selection	7007874
100451903	100451926	3	-	27260156	L33	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.3496754547373295	[363]	[398,233,271,453]	7	hSpCas9	negative selection	7007875
100429770	100429793	3	-	27260156	L33	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.5522211389796011	[881]	[1320,556,862,1120]	9	hSpCas9	negative selection	7007876
100455894	100455917	3	+	27260156	L33	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.4112218019218512	[169]	[220,69,178,227]	8	hSpCas9	negative selection	7072134
100429840	100429863	3	-	27260156	L33	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.2787694672282004	[738]	[617,260,416,518]	-6	hSpCas9	negative selection	7072135
100455861	100455884	3	+	27260156	L33	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.59928765945123	[11]	[3,15,11,10]	9	hSpCas9	negative selection	7072136
100451789	100451812	3	+	27260156	K562	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.2637493351273702	[360]	[459,234,453,385]	3	hSpCas9	negative selection	7129125
100451903	100451926	3	-	27260156	K562	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.20389346860396682	[363]	[578,256,472,207]	2	hSpCas9	negative selection	7129126
100429770	100429793	3	-	27260156	K562	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	1.0252044215242644	[881]	[1951,916,2593,969]	9	hSpCas9	negative selection	7129127
100455894	100455917	3	+	27260156	K562	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.0941092475971983	[169]	[116,210,233,88]	1	hSpCas9	negative selection	7193385
100429840	100429863	3	-	27260156	K562	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	0.10311761053420665	[738]	[460,891,1062,421]	1	hSpCas9	negative selection	7193386
100455861	100455884	3	+	27260156	K562	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-3.088042853315338	[11]	[0,0,1,0]	-9	hSpCas9	negative selection	7193387
100451789	100451812	3	+	27260156	HT29	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.06643107193396591	[360]	[394,549,553,351]	1	hSpCas9	negative selection	7250376
100451903	100451926	3	-	27260156	HT29	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.03457636798134589	[363]	[512,346,343,509]	0	hSpCas9	negative selection	7250377
100429770	100429793	3	-	27260156	HT29	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.8005317322722677	[881]	[1949,2000,1996,1563]	9	hSpCas9	negative selection	7250378
100455894	100455917	3	+	27260156	HT29	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.1847935602501396	[169]	[202,199,227,293]	3	hSpCas9	negative selection	7314636
100429840	100429863	3	-	27260156	HT29	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.049202832303196664	[738]	[836,1066,832,757]	-1	hSpCas9	negative selection	7314637
100455861	100455884	3	+	27260156	HT29	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-1.0711546877994955	[11]	[0,3,5,14]	-9	hSpCas9	negative selection	7314638
100451789	100451812	3	+	27260156	MHHES1	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.27794254493615367	[360]	[393,569,482,505]	5	hSpCas9	negative selection	7371627
100451903	100451926	3	-	27260156	MHHES1	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.3199756262245551	[363]	[480,353,339,185]	-6	hSpCas9	negative selection	7371628
100429770	100429793	3	-	27260156	MHHES1	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.8868848789483953	[881]	[2159,2299,1853,1222]	9	hSpCas9	negative selection	7371629
100455894	100455917	3	+	27260156	MHHES1	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.6237116997217983	[169]	[349,296,370,187]	9	hSpCas9	negative selection	7435887
100429840	100429863	3	-	27260156	MHHES1	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.411444515995932	[738]	[487,879,771,409]	-6	hSpCas9	negative selection	7435888
100455861	100455884	3	+	27260156	MHHES1	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-0.04268610550236751	[11]	[0,0,0,39]	-1	hSpCas9	negative selection	7435889
100451789	100451812	3	+	27260156	MEWO	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	-0.26328785591627274	[360]	[308,174,365]	-5	hSpCas9	negative selection	7492878
100451903	100451926	3	-	27260156	MEWO	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.14365638020835278	[363]	[340,313,466]	3	hSpCas9	negative selection	7492879
100429770	100429793	3	-	27260156	MEWO	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.36754989457316267	[881]	[1132,1023,1049]	7	hSpCas9	negative selection	7492880
100455894	100455917	3	+	27260156	MEWO	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.6912042883478194	[169]	[238,234,292]	9	hSpCas9	negative selection	7557138
100429840	100429863	3	-	27260156	MEWO	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.09801450810368684	[738]	[700,527,719]	-2	hSpCas9	negative selection	7557139
100455861	100455884	3	+	27260156	MEWO	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.059722557322009706	[11]	[5,10,16]	1	hSpCas9	negative selection	7557140
100451789	100451812	3	+	27260156	LNCAPCLONEFGC	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.1680641878085245	[360]	[390,302,338,435]	2	hSpCas9	negative selection	7614129
100451903	100451926	3	-	27260156	LNCAPCLONEFGC	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.31638127124806814	[363]	[299,225,224,303]	-5	hSpCas9	negative selection	7614130
100429770	100429793	3	-	27260156	LNCAPCLONEFGC	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.7985698061360026	[881]	[1375,1165,1578,1479]	9	hSpCas9	negative selection	7614131
100455894	100455917	3	+	27260156	LNCAPCLONEFGC	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.29813988831856	[169]	[163,147,239,215]	5	hSpCas9	negative selection	7678389
100429840	100429863	3	-	27260156	LNCAPCLONEFGC	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.33179144567824614	[738]	[421,483,642,599]	-5	hSpCas9	negative selection	7678390
100455861	100455884	3	+	27260156	LNCAPCLONEFGC	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-0.6598403802186095	[11]	[2,19,1,0]	-7	hSpCas9	negative selection	7678391
100451789	100451812	3	+	27260156	PANC0327	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.4834582849125382	[360]	[514,344,452,498]	7	hSpCas9	negative selection	7735380
100451903	100451926	3	-	27260156	PANC0327	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.2928533490710902	[363]	[197,272,231,345]	-4	hSpCas9	negative selection	7735381
100429770	100429793	3	-	27260156	PANC0327	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.5208410627489487	[881]	[1142,1065,1019,1275]	7	hSpCas9	negative selection	7735382
100455894	100455917	3	+	27260156	PANC0327	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	-0.3340159870450987	[169]	[205,74,101,108]	-5	hSpCas9	negative selection	7799640
100429840	100429863	3	-	27260156	PANC0327	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.11359136726902341	[738]	[615,511,706,604]	-2	hSpCas9	negative selection	7799641
100455861	100455884	3	+	27260156	PANC0327	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.5139841384762525	[11]	[1,36,16,0]	7	hSpCas9	negative selection	7799642
100451789	100451812	3	+	27260156	NCIH2009	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.8801342448717382	[360]	[1046,864,895]	9	hSpCas9	negative selection	7856631
100451903	100451926	3	-	27260156	NCIH2009	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.1306980954319855	[363]	[722,626,350]	1	hSpCas9	negative selection	7856632
100429770	100429793	3	-	27260156	NCIH2009	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.8179239771122914	[881]	[2718,2307,1591]	9	hSpCas9	negative selection	7856633
100455894	100455917	3	+	27260156	NCIH2009	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.6222340479417783	[169]	[455,312,345]	8	hSpCas9	negative selection	7920891
100429840	100429863	3	-	27260156	NCIH2009	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.4208435419036063	[738]	[910,831,595]	-5	hSpCas9	negative selection	7920892
100455861	100455884	3	+	27260156	NCIH2009	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-0.8825178136656859	[11]	[6,0,18]	-8	hSpCas9	negative selection	7920893
100451789	100451812	3	+	27260156	NCIH1373	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.8409725678954818	[360]	[876,725,675,166]	8	hSpCas9	negative selection	7977882
100451903	100451926	3	-	27260156	NCIH1373	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.5388517902897088	[363]	[1071,383,674,82]	5	hSpCas9	negative selection	7977883
100429770	100429793	3	-	27260156	NCIH1373	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	1.3594510546080643	[881]	[2728,2487,2236,717]	9	hSpCas9	negative selection	7977884
100455894	100455917	3	+	27260156	NCIH1373	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	1.0477375197412466	[169]	[699,406,213,77]	9	hSpCas9	negative selection	8042142
100429840	100429863	3	-	27260156	NCIH1373	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-1.030246270459775	[738]	[569,116,561,111]	-8	hSpCas9	negative selection	8042143
100455861	100455884	3	+	27260156	NCIH1373	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-1.6937656442896039	[11]	[1,2,3,1]	-9	hSpCas9	negative selection	8042144
100451789	100451812	3	+	27260156	PATU8902	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.6140639959885	[360]	[772,808,892,536]	6	hSpCas9	negative selection	8099133
100451903	100451926	3	-	27260156	PATU8902	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.06627606899446986	[363]	[518,523,620,417]	0	hSpCas9	negative selection	8099134
100429770	100429793	3	-	27260156	PATU8902	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.9974024657376618	[881]	[2503,2468,2235,2660]	9	hSpCas9	negative selection	8099135
100455894	100455917	3	+	27260156	PATU8902	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.03806196883572599	[169]	[515,86,153,230]	0	hSpCas9	negative selection	8163393
100429840	100429863	3	-	27260156	PATU8902	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.2514711463711439	[738]	[1193,1338,251,816]	-3	hSpCas9	negative selection	8163394
100455861	100455884	3	+	27260156	PATU8902	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.8766306258438421	[11]	[28,1,10,92]	8	hSpCas9	negative selection	8163395
100451789	100451812	3	+	27260156	PANC1	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.10184090633071419	[360]	[370,521,315,179]	1	hSpCas9	negative selection	8220384
100451903	100451926	3	-	27260156	PANC1	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.33253915630050634	[363]	[266,293,343,115]	-5	hSpCas9	negative selection	8220385
100429770	100429793	3	-	27260156	PANC1	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.8072356019956736	[881]	[1193,1463,1628,1069]	9	hSpCas9	negative selection	8220386
100455894	100455917	3	+	27260156	PANC1	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.12385771773019005	[169]	[174,231,142,106]	2	hSpCas9	negative selection	8284644
100429840	100429863	3	-	27260156	PANC1	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.49195731250690433	[738]	[346,644,439,413]	-6	hSpCas9	negative selection	8284645
100455861	100455884	3	+	27260156	PANC1	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.25640645693396813	[11]	[20,21,3,4]	4	hSpCas9	negative selection	8284646
100451789	100451812	3	+	27260156	PANC0813	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.42275903087258654	[360]	[554,550,619,546]	6	hSpCas9	negative selection	8341635
100451903	100451926	3	-	27260156	PANC0813	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.13759523253886138	[363]	[431,577,401,464]	2	hSpCas9	negative selection	8341636
100429770	100429793	3	-	27260156	PANC0813	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.9439729533619386	[881]	[1976,2175,2029,1795]	9	hSpCas9	negative selection	8341637
100455894	100455917	3	+	27260156	PANC0813	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.4747768378907866	[169]	[327,276,316,196]	7	hSpCas9	negative selection	8405895
100429840	100429863	3	-	27260156	PANC0813	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.5137045014650139	[738]	[769,449,649,577]	-6	hSpCas9	negative selection	8405896
100455861	100455884	3	+	27260156	PANC0813	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-0.6932209464686627	[11]	[5,25,1,0]	-7	hSpCas9	negative selection	8405897
100451789	100451812	3	+	27260156	RDES	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.45172475466791345	[360]	[541,508,424,820]	7	hSpCas9	negative selection	8462886
100451903	100451926	3	-	27260156	RDES	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.11821379644818486	[363]	[451,397,503,455]	2	hSpCas9	negative selection	8462887
100429770	100429793	3	-	27260156	RDES	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.873045866575947	[881]	[1682,1464,2173,2188]	9	hSpCas9	negative selection	8462888
100455894	100455917	3	+	27260156	RDES	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.38149677713722285	[169]	[215,236,279,294]	6	hSpCas9	negative selection	8527146
100429840	100429863	3	-	27260156	RDES	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.23100017740187007	[738]	[681,761,661,776]	-4	hSpCas9	negative selection	8527147
100455861	100455884	3	+	27260156	RDES	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.3685661064185366	[11]	[34,2,10,18]	6	hSpCas9	negative selection	8527148
100451789	100451812	3	+	27260156	PC3	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	-0.43276654601202685	[360]	[227,144,411,330]	-7	hSpCas9	negative selection	8584137
100451903	100451926	3	-	27260156	PC3	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.16391696552437607	[363]	[261,280,476,324]	-4	hSpCas9	negative selection	8584138
100429770	100429793	3	-	27260156	PC3	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.515604862703685	[881]	[879,959,2126,1456]	9	hSpCas9	negative selection	8584139
100455894	100455917	3	+	27260156	PC3	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.15064686520039117	[169]	[126,238,246,164]	3	hSpCas9	negative selection	8648397
100429840	100429863	3	-	27260156	PC3	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.46814931877168725	[738]	[277,521,992,586]	-8	hSpCas9	negative selection	8648398
100455861	100455884	3	+	27260156	PC3	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.18786021295202904	[11]	[8,1,41,13]	4	hSpCas9	negative selection	8648399
100451789	100451812	3	+	27260156	PATU8988T	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	-0.05396327190546979	[360]	[355,463,278,250]	-1	hSpCas9	negative selection	8705388
100451903	100451926	3	-	27260156	PATU8988T	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.2536096067756186	[363]	[235,396,252,304]	-4	hSpCas9	negative selection	8705389
100429770	100429793	3	-	27260156	PATU8988T	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.5633246237749557	[881]	[985,1112,1268,1689]	8	hSpCas9	negative selection	8705390
100455894	100455917	3	+	27260156	PATU8988T	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.6786026988951587	[169]	[99,187,465,289]	9	hSpCas9	negative selection	8769648
100429840	100429863	3	-	27260156	PATU8988T	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.046637388467568486	[738]	[521,775,870,593]	-1	hSpCas9	negative selection	8769649
100455861	100455884	3	+	27260156	PATU8988T	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.6422304894641302	[11]	[4,5,1,61]	9	hSpCas9	negative selection	8769650
100451789	100451812	3	+	27260156	T47D	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.05657278472036137	[360]	[392,433,417,506]	1	hSpCas9	negative selection	8826639
100451903	100451926	3	-	27260156	T47D	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.23919078534266466	[363]	[424,553,530,485]	5	hSpCas9	negative selection	8826640
100429770	100429793	3	-	27260156	T47D	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.7163914357900031	[881]	[1719,1583,1615,1847]	9	hSpCas9	negative selection	8826641
100455894	100455917	3	+	27260156	T47D	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.22752528454721288	[169]	[200,278,282,156]	5	hSpCas9	negative selection	8890899
100429840	100429863	3	-	27260156	T47D	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.07053500247930722	[738]	[928,761,719,876]	-1	hSpCas9	negative selection	8890900
100455861	100455884	3	+	27260156	T47D	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-0.028572659281556945	[11]	[12,21,9,8]	0	hSpCas9	negative selection	8890901
100451789	100451812	3	+	27260156	SU8686	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.2704552323490164	[360]	[404,440,353,540]	4	hSpCas9	negative selection	8947890
100451903	100451926	3	-	27260156	SU8686	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.2608829152438993	[363]	[274,432,204,266]	-4	hSpCas9	negative selection	8947891
100429770	100429793	3	-	27260156	SU8686	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.9032108731746716	[881]	[1353,1469,1808,2016]	9	hSpCas9	negative selection	8947892
100455894	100455917	3	+	27260156	SU8686	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.40059985907934514	[169]	[196,156,298,253]	6	hSpCas9	negative selection	9012150
100429840	100429863	3	-	27260156	SU8686	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.5022837403927419	[738]	[426,478,545,650]	-7	hSpCas9	negative selection	9012151
100455861	100455884	3	+	27260156	SU8686	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.5854871616163244	[11]	[29,13,8,16]	8	hSpCas9	negative selection	9012152
100451789	100451812	3	+	27260156	SKES1	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	-0.09153295712163256	[360]	[460,279,392,235]	-2	hSpCas9	negative selection	9069141
100451903	100451926	3	-	27260156	SKES1	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.04392635117900168	[363]	[421,294,418,355]	1	hSpCas9	negative selection	9069142
100429770	100429793	3	-	27260156	SKES1	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.6749927578804803	[881]	[1403,1732,1299,1228]	9	hSpCas9	negative selection	9069143
100455894	100455917	3	+	27260156	SKES1	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.5636774631490057	[169]	[319,234,261,196]	9	hSpCas9	negative selection	9133401
100429840	100429863	3	-	27260156	SKES1	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.28417415293048576	[738]	[621,516,713,557]	-6	hSpCas9	negative selection	9133402
100455861	100455884	3	+	27260156	SKES1	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	0.3891977739353285	[11]	[5,7,39,6]	7	hSpCas9	negative selection	9133403
100451789	100451812	3	+	27260156	TOV112D	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	-0.16910150491556603	[360]	[311,410,372,213]	-3	hSpCas9	negative selection	9190392
100451903	100451926	3	-	27260156	TOV112D	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.016825904470991415	[363]	[364,365,367,343]	0	hSpCas9	negative selection	9190393
100429770	100429793	3	-	27260156	TOV112D	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.6044234456530783	[881]	[1175,1391,1567,1234]	9	hSpCas9	negative selection	9190394
100455894	100455917	3	+	27260156	TOV112D	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.4790671057573256	[169]	[166,284,239,261]	8	hSpCas9	negative selection	9254652
100429840	100429863	3	-	27260156	TOV112D	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.07556467619096807	[738]	[782,563,728,704]	-1	hSpCas9	negative selection	9254653
100455861	100455884	3	+	27260156	TOV112D	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-0.71245667142367	[11]	[14,2,6,3]	-8	hSpCas9	negative selection	9254654
100451789	100451812	3	+	27260156	TC71	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.08433585134836413	[360]	[314,385,510,428]	2	hSpCas9	negative selection	9311643
100451903	100451926	3	-	27260156	TC71	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	0.0083400129972786	[363]	[420,356,347,447]	0	hSpCas9	negative selection	9311644
100429770	100429793	3	-	27260156	TC71	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.6433334050817562	[881]	[1415,1466,1524,1499]	9	hSpCas9	negative selection	9311645
100455894	100455917	3	+	27260156	TC71	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	-0.1165539115449219	[169]	[202,140,157,169]	-3	hSpCas9	negative selection	9375903
100429840	100429863	3	-	27260156	TC71	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.3071540612886614	[738]	[546,659,679,676]	-7	hSpCas9	negative selection	9375904
100455861	100455884	3	+	27260156	TC71	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-0.9644257345018827	[11]	[0,9,12,1]	-9	hSpCas9	negative selection	9375905
100451789	100451812	3	+	27260156	TC32	viability	TTCGATGCCGTAGCCACGTACGG	LNP1	ENSG00000206535	0.18255182433000638	[360]	[282,274,563,487]	3	hSpCas9	negative selection	9432894
100451903	100451926	3	-	27260156	TC32	viability	AAAGCACAGTTGCCGTTCAAAGG	LNP1	ENSG00000206535	-0.3089549865198893	[363]	[240,236,393,253]	-5	hSpCas9	negative selection	9432895
100429770	100429793	3	-	27260156	TC32	viability	CCAGAAGCTGCTCATCCATTTGG	LNP1	ENSG00000206535	0.7206807766432187	[881]	[1353,1007,1545,1657]	9	hSpCas9	negative selection	9432896
100455894	100455917	3	+	27260156	TC32	viability	ATGGCTCCCCTGTTTGAAAAAGG	LNP1	ENSG00000206535	0.296626211456104	[169]	[133,194,327,143]	5	hSpCas9	negative selection	9497154
100429840	100429863	3	-	27260156	TC32	viability	TGTGACTGGTGGCTTGCAGTCGG	LNP1	ENSG00000206535	-0.48742854932949026	[738]	[507,368,557,577]	-7	hSpCas9	negative selection	9497155
100455861	100455884	3	+	27260156	TC32	viability	AGCTCTAGGAAAGAAGAGCATGG	LNP1	ENSG00000206535	-0.3817931585957606	[11]	[9,0,4,20]	-6	hSpCas9	negative selection	9497156
100429878	100429901	3	-	27869803	HPAFII	viability after 27 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.5451305023116108	[190]	[16,111,NaN]	-4	hSpCas9	negative selection	9581629
100429878	100429901	3	-	27869803	HPAFII	viability after 15 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.5215317750115276	[190]	[142,142,NaN]	-5	hSpCas9	negative selection	9664078
100429878	100429901	3	-	27869803	ASPC1	viability after 36 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	0.9302659381324618	[353]	[127,463,126]	8	hSpCas9	negative selection	9746527
100429878	100429901	3	-	27869803	PATU8988S	viability after 35 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-1.1461318694053553	[293]	[53,52,NaN]	-8	hSpCas9	negative selection	9828976
100429878	100429901	3	-	27869803	PATU8988S	viability after 31 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.7521239495541816	[293]	[84,49,NaN]	-7	hSpCas9	negative selection	9911425
100429878	100429901	3	-	27869803	HPAFII	viability after 35 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.3770522520353623	[190]	[41,110,NaN]	-2	hSpCas9	negative selection	9993874
100429878	100429901	3	-	27869803	HPAFII	viability after 31 days	ATGACAATCACTCACTGGGCAGG	LNP1	ENSG00000206535	-0.4378005973786877	[190]	[3,160,NaN]	-3	hSpCas9	negative selection	10076323
100429782	100429805	3	+	28162770	P31FUJ	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.10452598376672911	[204]	[258]	1	hSpCas9	negative selection	10185179
100451835	100451858	3	+	28162770	P31FUJ	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	-0.32810916451010586	[218]	[204]	-3	hSpCas9	negative selection	10185180
100429792	100429815	3	+	28162770	P31FUJ	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-1.8177647051355348	[35]	[11]	-8	hSpCas9	negative selection	10185181
100429851	100429874	3	-	28162770	P31FUJ	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.04949410358004824	[619]	[753]	0	hSpCas9	negative selection	10185182
100429810	100429833	3	+	28162770	P31FUJ	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	-0.19948213121435215	[213]	[218]	-2	hSpCas9	negative selection	10185183
100451722	100451745	3	-	28162770	P31FUJ	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.41972358011941224	[291]	[458]	5	hSpCas9	negative selection	10185184
100429772	100429795	3	+	28162770	P31FUJ	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.3891976756313072	[140]	[216]	4	hSpCas9	negative selection	10185185
100429837	100429860	3	-	28162770	P31FUJ	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	0.9620511933237876	[203]	[466]	9	hSpCas9	negative selection	10185186
100451851	100451874	3	-	28162770	P31FUJ	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.6951061724632228	[953]	[1814]	7	hSpCas9	negative selection	10185187
100429869	100429892	3	-	28162770	P31FUJ	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	0.28843469869639016	[107]	[154]	3	hSpCas9	negative selection	10185188
100429782	100429805	3	+	28162770	TF1	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	NaN	[NaN]	[261]	1	hSpCas9	negative selection	10354545
100451835	100451858	3	+	28162770	TF1	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	NaN	[NaN]	[101]	1	hSpCas9	negative selection	10354546
100429792	100429815	3	+	28162770	TF1	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10354547
100429851	100429874	3	-	28162770	TF1	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	NaN	[NaN]	[373]	1	hSpCas9	negative selection	10354548
100429810	100429833	3	+	28162770	TF1	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	NaN	[NaN]	[158]	1	hSpCas9	negative selection	10354549
100451722	100451745	3	-	28162770	TF1	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	NaN	[NaN]	[301]	1	hSpCas9	negative selection	10354550
100429772	100429795	3	+	28162770	TF1	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10354551
100429837	100429860	3	-	28162770	TF1	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	NaN	[NaN]	[214]	1	hSpCas9	negative selection	10354552
100451851	100451874	3	-	28162770	TF1	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	NaN	[NaN]	[1871]	1	hSpCas9	negative selection	10354553
100429869	100429892	3	-	28162770	TF1	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	NaN	[NaN]	[145]	1	hSpCas9	negative selection	10354554
100429782	100429805	3	+	28162770	SKM1	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	-0.5211352186624729	[68]	[84]	-4	hSpCas9	negative selection	10523911
100451835	100451858	3	+	28162770	SKM1	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	0.7305393250067731	[29]	[87]	7	hSpCas9	negative selection	10523912
100429792	100429815	3	+	28162770	SKM1	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-1.0850361038557996	[17]	[14]	-7	hSpCas9	negative selection	10523913
100429851	100429874	3	-	28162770	SKM1	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	-0.3682837305791019	[137]	[188]	-3	hSpCas9	negative selection	10523914
100429810	100429833	3	+	28162770	SKM1	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	-0.28666996502544984	[68]	[99]	-2	hSpCas9	negative selection	10523915
100451722	100451745	3	-	28162770	SKM1	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.16092478861905313	[84]	[167]	1	hSpCas9	negative selection	10523916
100429772	100429795	3	+	28162770	SKM1	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.8362097847297891	[31]	[100]	7	hSpCas9	negative selection	10523917
100429837	100429860	3	-	28162770	SKM1	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	0.6227831446508904	[35]	[97]	6	hSpCas9	negative selection	10523918
100451851	100451874	3	-	28162770	SKM1	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.5181721057933668	[219]	[556]	5	hSpCas9	negative selection	10523919
100429869	100429892	3	-	28162770	SKM1	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	1.122288869391707	[32]	[126]	9	hSpCas9	negative selection	10523920
100429782	100429805	3	+	28162770	SKM1	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	-0.5211352186624729	[68]	[84]	-4	hSpCas9	negative selection	10693277
100451835	100451858	3	+	28162770	SKM1	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	0.7305393250067731	[29]	[87]	7	hSpCas9	negative selection	10693278
100429792	100429815	3	+	28162770	SKM1	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-1.0850361038557996	[17]	[14]	-7	hSpCas9	negative selection	10693279
100429851	100429874	3	-	28162770	SKM1	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	-0.3682837305791019	[137]	[188]	-3	hSpCas9	negative selection	10693280
100429810	100429833	3	+	28162770	SKM1	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	-0.28666996502544984	[68]	[99]	-2	hSpCas9	negative selection	10693281
100451722	100451745	3	-	28162770	SKM1	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.16092478861905313	[84]	[167]	1	hSpCas9	negative selection	10693282
100429772	100429795	3	+	28162770	SKM1	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.8362097847297891	[31]	[100]	7	hSpCas9	negative selection	10693283
100429837	100429860	3	-	28162770	SKM1	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	0.6227831446508904	[35]	[97]	6	hSpCas9	negative selection	10693284
100451851	100451874	3	-	28162770	SKM1	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.5181721057933668	[219]	[556]	5	hSpCas9	negative selection	10693285
100429869	100429892	3	-	28162770	SKM1	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	1.122288869391707	[32]	[126]	9	hSpCas9	negative selection	10693286
100429782	100429805	3	+	28162770	PL21	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.00020204398056808404	[169]	[73]	0	hSpCas9	negative selection	10862643
100451835	100451858	3	+	28162770	PL21	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	-0.5325765066755281	[112]	[33]	-4	hSpCas9	negative selection	10862644
100429792	100429815	3	+	28162770	PL21	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-1.455212214123234	[62]	[9]	-7	hSpCas9	negative selection	10862645
100429851	100429874	3	-	28162770	PL21	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.9817160953558177	[483]	[415]	7	hSpCas9	negative selection	10862646
100429810	100429833	3	+	28162770	PL21	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	0.47144163630671443	[231]	[139]	4	hSpCas9	negative selection	10862647
100451722	100451745	3	-	28162770	PL21	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.10244294060218695	[335]	[156]	0	hSpCas9	negative selection	10862648
100429772	100429795	3	+	28162770	PL21	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	-0.6411626394916217	[85]	[23]	-4	hSpCas9	negative selection	10862649
100429837	100429860	3	-	28162770	PL21	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	1.0705043340727247	[127]	[116]	8	hSpCas9	negative selection	10862650
100451851	100451874	3	-	28162770	PL21	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.7989742897920338	[827]	[626]	6	hSpCas9	negative selection	10862651
100429869	100429892	3	-	28162770	PL21	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	1.967966172360287	[73]	[125]	9	hSpCas9	negative selection	10862652
100429782	100429805	3	+	28162770	P31FUJ	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.10452598376672911	[204]	[258]	1	hSpCas9	negative selection	11032009
100451835	100451858	3	+	28162770	P31FUJ	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	-0.32810916451010586	[218]	[204]	-3	hSpCas9	negative selection	11032010
100429792	100429815	3	+	28162770	P31FUJ	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-1.8177647051355348	[35]	[11]	-8	hSpCas9	negative selection	11032011
100429851	100429874	3	-	28162770	P31FUJ	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.04949410358004824	[619]	[753]	0	hSpCas9	negative selection	11032012
100429810	100429833	3	+	28162770	P31FUJ	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	-0.19948213121435215	[213]	[218]	-2	hSpCas9	negative selection	11032013
100451722	100451745	3	-	28162770	P31FUJ	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.41972358011941224	[291]	[458]	5	hSpCas9	negative selection	11032014
100429772	100429795	3	+	28162770	P31FUJ	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.3891976756313072	[140]	[216]	4	hSpCas9	negative selection	11032015
100429837	100429860	3	-	28162770	P31FUJ	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	0.9620511933237876	[203]	[466]	9	hSpCas9	negative selection	11032016
100451851	100451874	3	-	28162770	P31FUJ	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.6951061724632228	[953]	[1814]	7	hSpCas9	negative selection	11032017
100429869	100429892	3	-	28162770	P31FUJ	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	0.28843469869639016	[107]	[154]	3	hSpCas9	negative selection	11032018
100429782	100429805	3	+	28162770	OCIAML5	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	-0.11115379218112786	[145]	[243]	-1	hSpCas9	negative selection	11201375
100451835	100451858	3	+	28162770	OCIAML5	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	0.1118641744284814	[80]	[157]	0	hSpCas9	negative selection	11201376
100429792	100429815	3	+	28162770	OCIAML5	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-1.947223803904337	[46]	[21]	-8	hSpCas9	negative selection	11201377
100429851	100429874	3	-	28162770	OCIAML5	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.23948736702544293	[289]	[617]	2	hSpCas9	negative selection	11201378
100429810	100429833	3	+	28162770	OCIAML5	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	0.30547470612248284	[116]	[260]	2	hSpCas9	negative selection	11201379
100451722	100451745	3	-	28162770	OCIAML5	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.5601281786460215	[126]	[337]	5	hSpCas9	negative selection	11201380
100429772	100429795	3	+	28162770	OCIAML5	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.9601871506064463	[83]	[294]	8	hSpCas9	negative selection	11201381
100429837	100429860	3	-	28162770	OCIAML5	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	0.5171672388017221	[83]	[216]	4	hSpCas9	negative selection	11201382
100451851	100451874	3	-	28162770	OCIAML5	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.9257713047177369	[521]	[1789]	7	hSpCas9	negative selection	11201383
100429869	100429892	3	-	28162770	OCIAML5	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	-0.13122064206106798	[53]	[88]	-1	hSpCas9	negative selection	11201384
100429782	100429805	3	+	28162770	EOL1	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.41890772351078426	[344]	[242]	4	hSpCas9	negative selection	11370741
100451835	100451858	3	+	28162770	EOL1	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	-0.6911115263735379	[189]	[61]	-5	hSpCas9	negative selection	11370742
100429792	100429815	3	+	28162770	EOL1	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-5.56730532475914	[89]	[0]	-9	hSpCas9	negative selection	11370743
100429851	100429874	3	-	28162770	EOL1	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.7666578350485704	[954]	[855]	6	hSpCas9	negative selection	11370744
100429810	100429833	3	+	28162770	EOL1	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	-0.8540958538455422	[397]	[115]	-5	hSpCas9	negative selection	11370745
100451722	100451745	3	-	28162770	EOL1	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.4747448541310142	[615]	[450]	4	hSpCas9	negative selection	11370746
100429772	100429795	3	+	28162770	EOL1	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.6462466090834302	[113]	[93]	6	hSpCas9	negative selection	11370747
100429837	100429860	3	-	28162770	EOL1	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	1.4112081986798866	[166]	[233]	9	hSpCas9	negative selection	11370748
100451851	100451874	3	-	28162770	EOL1	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.9823734429728301	[1026]	[1068]	8	hSpCas9	negative selection	11370749
100429869	100429892	3	-	28162770	EOL1	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	0.74654946959254	[111]	[98]	6	hSpCas9	negative selection	11370750
100429782	100429805	3	+	28162770	MOLM13	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.3399366505775823	[270]	[247]	2	hSpCas9	negative selection	11540107
100451835	100451858	3	+	28162770	MOLM13	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	0.7103474259351323	[152]	[180]	5	hSpCas9	negative selection	11540108
100429792	100429815	3	+	28162770	MOLM13	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	1.1719045539094985	[61]	[100]	8	hSpCas9	negative selection	11540109
100429851	100429874	3	-	28162770	MOLM13	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.9908575952072223	[633]	[910]	7	hSpCas9	negative selection	11540110
100429810	100429833	3	+	28162770	MOLM13	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	1.1207089695108667	[352]	[554]	8	hSpCas9	negative selection	11540111
100451722	100451745	3	-	28162770	MOLM13	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.7012729808401156	[466]	[548]	5	hSpCas9	negative selection	11540112
100429772	100429795	3	+	28162770	MOLM13	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	-0.687388843933332	[195]	[87]	-4	hSpCas9	negative selection	11540113
100429837	100429860	3	-	28162770	MOLM13	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	0.5587428119956924	[199]	[212]	4	hSpCas9	negative selection	11540114
100451851	100451874	3	-	28162770	MOLM13	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.3533002497426456	[1217]	[1124]	2	hSpCas9	negative selection	11540115
100429869	100429892	3	-	28162770	MOLM13	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	1.1630348000161579	[83]	[135]	8	hSpCas9	negative selection	11540116
100429782	100429805	3	+	28162770	HEL	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.4860133283129038	[271]	[243]	4	hSpCas9	negative selection	11709473
100451835	100451858	3	+	28162770	HEL	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	0.44375779727396153	[162]	[141]	4	hSpCas9	negative selection	11709474
100429792	100429815	3	+	28162770	HEL	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-3.922045786783169	[70]	[2]	-9	hSpCas9	negative selection	11709475
100429851	100429874	3	-	28162770	HEL	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.7598804940382626	[732]	[794]	6	hSpCas9	negative selection	11709476
100429810	100429833	3	+	28162770	HEL	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	0.8252833199737828	[214]	[243]	7	hSpCas9	negative selection	11709477
100451722	100451745	3	-	28162770	HEL	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.2973517642890058	[464]	[365]	2	hSpCas9	negative selection	11709478
100429772	100429795	3	+	28162770	HEL	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.1379466799631841	[104]	[73]	1	hSpCas9	negative selection	11709479
100429837	100429860	3	-	28162770	HEL	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	1.1635709953017974	[114]	[164]	8	hSpCas9	negative selection	11709480
100451851	100451874	3	-	28162770	HEL	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.34952203375452173	[994]	[811]	3	hSpCas9	negative selection	11709481
100429869	100429892	3	-	28162770	HEL	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	1.7041393766645003	[68]	[143]	9	hSpCas9	negative selection	11709482
100429782	100429805	3	+	28162770	MV411	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.10262099793099472	[177]	[160]	0	hSpCas9	negative selection	11878839
100451835	100451858	3	+	28162770	MV411	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	0.03403391267358216	[159]	[137]	0	hSpCas9	negative selection	11878840
100429792	100429815	3	+	28162770	MV411	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-1.2886153494574346	[28]	[9]	-7	hSpCas9	negative selection	11878841
100429851	100429874	3	-	28162770	MV411	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.07032217113398365	[527]	[466]	0	hSpCas9	negative selection	11878842
100429810	100429833	3	+	28162770	MV411	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	-0.0674357865706367	[254]	[204]	0	hSpCas9	negative selection	11878843
100451722	100451745	3	-	28162770	MV411	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.6397549735615355	[367]	[482]	6	hSpCas9	negative selection	11878844
100429772	100429795	3	+	28162770	MV411	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	-0.0697526250979239	[75]	[60]	0	hSpCas9	negative selection	11878845
100429837	100429860	3	-	28162770	MV411	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	-0.46625826406058357	[122]	[74]	-3	hSpCas9	negative selection	11878846
100451851	100451874	3	-	28162770	MV411	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.6689942434451601	[827]	[1108]	6	hSpCas9	negative selection	11878847
100429869	100429892	3	-	28162770	MV411	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	1.6624750500616192	[44]	[119]	9	hSpCas9	negative selection	11878848
100429782	100429805	3	+	28162770	MONOMAC1	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.10729718781307036	[131]	[162]	1	hSpCas9	negative selection	12048205
100451835	100451858	3	+	28162770	MONOMAC1	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	0.06947812750920179	[68]	[82]	0	hSpCas9	negative selection	12048206
100429792	100429815	3	+	28162770	MONOMAC1	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-3.482439065921802	[38]	[3]	-9	hSpCas9	negative selection	12048207
100429851	100429874	3	-	28162770	MONOMAC1	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.2662368378721376	[374]	[516]	2	hSpCas9	negative selection	12048208
100429810	100429833	3	+	28162770	MONOMAC1	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	-0.5068921096463411	[118]	[95]	-4	hSpCas9	negative selection	12048209
100451722	100451745	3	-	28162770	MONOMAC1	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.695410011785643	[173]	[322]	6	hSpCas9	negative selection	12048210
100429772	100429795	3	+	28162770	MONOMAC1	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.8029631529404465	[66]	[133]	7	hSpCas9	negative selection	12048211
100429837	100429860	3	-	28162770	MONOMAC1	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	-0.830254516387931	[75]	[48]	-6	hSpCas9	negative selection	12048212
100451851	100451874	3	-	28162770	MONOMAC1	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.5510738343595012	[489]	[822]	5	hSpCas9	negative selection	12048213
100429869	100429892	3	-	28162770	MONOMAC1	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	0.2840898426770626	[47]	[66]	3	hSpCas9	negative selection	12048214
100429782	100429805	3	+	28162770	OCIAML2	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.20524117167720535	[40]	[261]	2	hSpCas9	negative selection	12217571
100451835	100451858	3	+	28162770	OCIAML2	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	0.7099424203996596	[29]	[271]	7	hSpCas9	negative selection	12217572
100429792	100429815	3	+	28162770	OCIAML2	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	-0.5961607073260198	[8]	[32]	-4	hSpCas9	negative selection	12217573
100429851	100429874	3	-	28162770	OCIAML2	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.12654862518863408	[97]	[592]	1	hSpCas9	negative selection	12217574
100429810	100429833	3	+	28162770	OCIAML2	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	-0.32658345562545443	[49]	[220]	-3	hSpCas9	negative selection	12217575
100451722	100451745	3	-	28162770	OCIAML2	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	0.9132260187884031	[56]	[594]	8	hSpCas9	negative selection	12217576
100429772	100429795	3	+	28162770	OCIAML2	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.05661717762270757	[16]	[97]	0	hSpCas9	negative selection	12217577
100429837	100429860	3	-	28162770	OCIAML2	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	-0.2311638905467717	[35]	[169]	-2	hSpCas9	negative selection	12217578
100451851	100451874	3	-	28162770	OCIAML2	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.5957714004803485	[137]	[1155]	6	hSpCas9	negative selection	12217579
100429869	100429892	3	-	28162770	OCIAML2	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	1.0699385561205417	[10]	[127]	8	hSpCas9	negative selection	12217580
100429782	100429805	3	+	28162770	OCIAML3	viability	GCAGCTTCTGGGGCCACAGCTGG	LNP1	ENSG00000206535	0.3434078222978139	[52]	[202]	3	hSpCas9	negative selection	12386937
100451835	100451858	3	+	28162770	OCIAML3	viability	TGGGTCATTCAAGGAGCCACTGG	LNP1	ENSG00000206535	-0.23786383009888784	[49]	[127]	-2	hSpCas9	negative selection	12386938
100429792	100429815	3	+	28162770	OCIAML3	viability	GGGCCACAGCTGGAGAGAGGAGG	LNP1	ENSG00000206535	0.8080908032471825	[6]	[36]	7	hSpCas9	negative selection	12386939
100429851	100429874	3	-	28162770	OCIAML3	viability	GGAGGTTTTCCTGTGACTGGTGG	LNP1	ENSG00000206535	0.4794221418872857	[157]	[664]	4	hSpCas9	negative selection	12386940
100429810	100429833	3	+	28162770	OCIAML3	viability	GGAGGATCAGAGAGGACTCCGGG	LNP1	ENSG00000206535	-0.61538129111673	[67]	[133]	-5	hSpCas9	negative selection	12386941
100451722	100451745	3	-	28162770	OCIAML3	viability	GATGGAATTCTGGGAAGCACAGG	LNP1	ENSG00000206535	-0.3215482217011007	[88]	[214]	-3	hSpCas9	negative selection	12386942
100429772	100429795	3	+	28162770	OCIAML3	viability	AAATGGATGAGCAGCTTCTGGGG	LNP1	ENSG00000206535	0.9909548603969931	[33]	[203]	8	hSpCas9	negative selection	12386943
100429837	100429860	3	-	28162770	OCIAML3	viability	GACTGGTGGCTTGCAGTCGGTGG	LNP1	ENSG00000206535	0.7667397034537273	[43]	[225]	7	hSpCas9	negative selection	12386944
100451851	100451874	3	-	28162770	OCIAML3	viability	GATCTTCCTTTTGATTCCAGTGG	LNP1	ENSG00000206535	0.019524012593763906	[199]	[611]	0	hSpCas9	negative selection	12386945
100429869	100429892	3	-	28162770	OCIAML3	viability	ACTCACTGGGCAGGGCAGGGAGG	LNP1	ENSG00000206535	0.6244158788093391	[25]	[120]	6	hSpCas9	negative selection	12386946