Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 79705
• Symbol: LRRK1
• Description: leucine rich repeat kinase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/LRRK1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
101021854	101021877	15	-	26472758	Jiyoye	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	0.648183481009668	[21]	[25]	5	hSpCas9	negative selection	93167
100988647	100988670	15	-	26472758	Jiyoye	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	1.6295678028423213	[59]	[139]	8	hSpCas9	negative selection	93168
101022495	101022518	15	+	26472758	Jiyoye	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	0.38548031040655417	[133]	[131]	3	hSpCas9	negative selection	93169
100924665	100924688	15	+	26472758	Jiyoye	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	1.5501333353479165	[23]	[52]	8	hSpCas9	negative selection	93170
100924695	100924718	15	+	26472758	Jiyoye	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.5714648482787528	[455]	[510]	4	hSpCas9	negative selection	93171
100973876	100973899	15	+	26472758	Jiyoye	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.3300075209834134	[95]	[90]	2	hSpCas9	negative selection	93172
100973890	100973913	15	+	26472758	Jiyoye	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	-0.14251164446775233	[100]	[68]	-1	hSpCas9	negative selection	93173
100983602	100983625	15	+	26472758	Jiyoye	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	0.5495283049172042	[134]	[148]	4	hSpCas9	negative selection	93174
100983620	100983643	15	+	26472758	Jiyoye	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-0.7232212557498016	[80]	[36]	-5	hSpCas9	negative selection	93175
101021854	101021877	15	-	26472758	KBM7	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-0.40867107782528156	[144,116]	[24,64]	-4	hSpCas9	negative selection	284285
100988647	100988670	15	-	26472758	KBM7	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	0.4236367297531404	[338,284]	[167,220]	4	hSpCas9	negative selection	284286
101022495	101022518	15	+	26472758	KBM7	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	-0.03884628651524791	[606,493]	[211,284]	0	hSpCas9	negative selection	284287
100924665	100924688	15	+	26472758	KBM7	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	0.5198343438719739	[143,103]	[51,109]	5	hSpCas9	negative selection	284288
100924695	100924718	15	+	26472758	KBM7	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.29932430298355817	[2125,1836]	[1265,1033]	3	hSpCas9	negative selection	284289
100973876	100973899	15	+	26472758	KBM7	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.5058886035393068	[603,500]	[382,352]	5	hSpCas9	negative selection	284290
100973890	100973913	15	+	26472758	KBM7	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	-0.027053090129931512	[287,166]	[33,163]	0	hSpCas9	negative selection	284291
100983602	100983625	15	+	26472758	KBM7	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	0.4976636526829839	[714,481]	[431,354]	5	hSpCas9	negative selection	284292
100983620	100983643	15	+	26472758	KBM7	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.5795491657352525	[165,133]	[80,125]	6	hSpCas9	negative selection	284293
101021854	101021877	15	-	26472758	Raji	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-1.9941544910884628	[102]	[5]	-8	hSpCas9	negative selection	475403
100988647	100988670	15	-	26472758	Raji	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	-0.5531299983547335	[195]	[30]	-4	hSpCas9	negative selection	475404
101022495	101022518	15	+	26472758	Raji	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	0.042092075121880304	[225]	[53]	0	hSpCas9	negative selection	475405
100924665	100924688	15	+	26472758	Raji	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	1.0749620576812222	[44]	[21]	8	hSpCas9	negative selection	475406
100924695	100924718	15	+	26472758	Raji	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.5793648314788897	[769]	[266]	5	hSpCas9	negative selection	475407
100973876	100973899	15	+	26472758	Raji	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.391889471510218	[288]	[87]	4	hSpCas9	negative selection	475408
100973890	100973913	15	+	26472758	Raji	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	0.15696556422415997	[142]	[36]	1	hSpCas9	negative selection	475409
100983602	100983625	15	+	26472758	Raji	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	0.1851386928880448	[306]	[80]	1	hSpCas9	negative selection	475410
100983620	100983643	15	+	26472758	Raji	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	1.392785754235848	[63]	[38]	9	hSpCas9	negative selection	475411
101021854	101021877	15	-	26472758	K562	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-1.018615678167347	[107]	[44]	-5	hSpCas9	negative selection	666521
100988647	100988670	15	-	26472758	K562	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	0.6486725512320496	[234]	[310]	5	hSpCas9	negative selection	666522
101022495	101022518	15	+	26472758	K562	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	0.41175593461960336	[495]	[556]	3	hSpCas9	negative selection	666523
100924665	100924688	15	+	26472758	K562	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	0.5847588596676896	[108]	[137]	5	hSpCas9	negative selection	666524
100924695	100924718	15	+	26472758	K562	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.6990374962105341	[1473]	[2019]	6	hSpCas9	negative selection	666525
100973876	100973899	15	+	26472758	K562	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.5817010694308454	[485]	[613]	5	hSpCas9	negative selection	666526
100973890	100973913	15	+	26472758	K562	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	1.019858469647289	[110]	[189]	8	hSpCas9	negative selection	666527
100983602	100983625	15	+	26472758	K562	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	0.2911352265734771	[394]	[407]	2	hSpCas9	negative selection	666528
100983620	100983643	15	+	26472758	K562	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	1.049402745261304	[86]	[151]	8	hSpCas9	negative selection	666529
100973943	100973966	15	-	26627737	DLD1	viability	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.8210868219271077	[385]	[189,262,191]	7	hSpCas9	negative selection	790031
100983620	100983643	15	+	26627737	DLD1	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.2366760123490499	[1637]	[930,593,326]	2	hSpCas9	negative selection	790032
100988709	100988732	15	+	26627737	DLD1	viability	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	0.26523792320543454	[552]	[130,352,153]	2	hSpCas9	negative selection	790033
100989264	100989287	15	+	26627737	DLD1	viability	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.028103771423294233	[644]	[153,183,246]	0	hSpCas9	negative selection	790034
101009026	101009049	15	-	26627737	DLD1	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.34422382597027357	[493]	[192,255,148]	3	hSpCas9	negative selection	790035
101010820	101010843	15	-	26627737	DLD1	viability	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.2823355332659237	[608]	[422,137,142]	3	hSpCas9	negative selection	790036
100973943	100973966	15	-	26627737	GBM cells	viability after 5 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.6799040929438899	[212]	[201,163]	8	hSpCas9	negative selection	872346
100983620	100983643	15	+	26627737	GBM cells	viability after 5 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.47940844066114763	[538]	[448,356]	7	hSpCas9	negative selection	872347
100988709	100988732	15	+	26627737	GBM cells	viability after 5 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	0.439122974702293	[250]	[191,172]	6	hSpCas9	negative selection	872348
100989264	100989287	15	+	26627737	GBM cells	viability after 5 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	0.07268094262239212	[249]	[155,125]	1	hSpCas9	negative selection	872349
101009026	101009049	15	-	26627737	GBM cells	viability after 5 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	-0.044300099022737	[273]	[128,155]	0	hSpCas9	negative selection	872350
101010820	101010843	15	-	26627737	GBM cells	viability after 5 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.3669358300962506	[273]	[190,187]	5	hSpCas9	negative selection	872351
100973943	100973966	15	-	26627737	GBM cells	viability after 13 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.38972700032297136	[212]	[146,154]	5	hSpCas9	negative selection	954661
100983620	100983643	15	+	26627737	GBM cells	viability after 13 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.5278034235458713	[538]	[371,461]	6	hSpCas9	negative selection	954662
100988709	100988732	15	+	26627737	GBM cells	viability after 13 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	0.4358500634219861	[250]	[213,159]	5	hSpCas9	negative selection	954663
100989264	100989287	15	+	26627737	GBM cells	viability after 13 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	0.1502204297054673	[249]	[176,128]	2	hSpCas9	negative selection	954664
101009026	101009049	15	-	26627737	GBM cells	viability after 13 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.06675067886298003	[273]	[190,126]	0	hSpCas9	negative selection	954665
101010820	101010843	15	-	26627737	GBM cells	viability after 13 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.7978042236753462	[273]	[258,257]	8	hSpCas9	negative selection	954666
100973943	100973966	15	-	26627737	GBM cells	viability after 21 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	1.0062658141944492	[212]	[221,241]	8	hSpCas9	negative selection	1036976
100983620	100983643	15	+	26627737	GBM cells	viability after 21 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.7293202666991494	[538]	[497,473]	7	hSpCas9	negative selection	1036977
100988709	100988732	15	+	26627737	GBM cells	viability after 21 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	-0.4041873392902628	[250]	[101,103]	-4	hSpCas9	negative selection	1036978
100989264	100989287	15	+	26627737	GBM cells	viability after 21 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	0.29315329295031156	[249]	[179,153]	3	hSpCas9	negative selection	1036979
101009026	101009049	15	-	26627737	GBM cells	viability after 21 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.494002005855054	[273]	[217,201]	5	hSpCas9	negative selection	1036980
101010820	101010843	15	-	26627737	GBM cells	viability after 21 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.6366540771472629	[273]	[232,229]	6	hSpCas9	negative selection	1036981
100973943	100973966	15	-	26627737	RPE1	viability after 9 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	1.6215548163718405	[488]	[381,585]	8	hSpCas9	negative selection	1119291
100983620	100983643	15	+	26627737	RPE1	viability after 9 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-0.9132333176807679	[3677]	[541,700]	-6	hSpCas9	negative selection	1119292
100988709	100988732	15	+	26627737	RPE1	viability after 9 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	2.5368342361445695	[120]	[166,287]	9	hSpCas9	negative selection	1119293
100989264	100989287	15	+	26627737	RPE1	viability after 9 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.25792944137220275	[1028]	[285,247]	-2	hSpCas9	negative selection	1119294
101009026	101009049	15	-	26627737	RPE1	viability after 9 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.6151694802672402	[844]	[416,389]	4	hSpCas9	negative selection	1119295
101010820	101010843	15	-	26627737	RPE1	viability after 9 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.17104984726519257	[385]	[70,219]	1	hSpCas9	negative selection	1119296
100973943	100973966	15	-	26627737	RPE1	viability after 12 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	1.1784043657834762	[488]	[240,356]	7	hSpCas9	negative selection	1201606
100983620	100983643	15	+	26627737	RPE1	viability after 12 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-1.064554696258319	[3677]	[470,473]	-6	hSpCas9	negative selection	1201607
100988709	100988732	15	+	26627737	RPE1	viability after 12 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	2.5805565934185855	[120]	[90,303]	9	hSpCas9	negative selection	1201608
100989264	100989287	15	+	26627737	RPE1	viability after 12 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.8079179749516361	[1028]	[171,142]	-5	hSpCas9	negative selection	1201609
101009026	101009049	15	-	26627737	RPE1	viability after 12 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.7131273748949251	[844]	[360,383]	4	hSpCas9	negative selection	1201610
101010820	101010843	15	-	26627737	RPE1	viability after 12 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.5800446897419569	[385]	[155,153]	4	hSpCas9	negative selection	1201611
100973943	100973966	15	-	26627737	RPE1	viability after 15 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	1.4483824067063784	[488]	[236,512]	7	hSpCas9	negative selection	1283921
100983620	100983643	15	+	26627737	RPE1	viability after 15 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-0.6970053914659857	[3677]	[709,575]	-4	hSpCas9	negative selection	1283922
100988709	100988732	15	+	26627737	RPE1	viability after 15 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	3.0247941447308984	[120]	[161,390]	9	hSpCas9	negative selection	1283923
100989264	100989287	15	+	26627737	RPE1	viability after 15 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.29765112538830313	[1028]	[218,253]	-2	hSpCas9	negative selection	1283924
101009026	101009049	15	-	26627737	RPE1	viability after 15 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.09187327254200525	[844]	[296,213]	0	hSpCas9	negative selection	1283925
101010820	101010843	15	-	26627737	RPE1	viability after 15 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.032853185502972115	[385]	[71,149]	0	hSpCas9	negative selection	1283926
100973943	100973966	15	-	26627737	RPE1	viability after 18 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	1.3795167456110242	[488]	[338,347]	7	hSpCas9	negative selection	1366236
100983620	100983643	15	+	26627737	RPE1	viability after 18 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-1.286975932979022	[3677]	[399,413]	-7	hSpCas9	negative selection	1366237
100988709	100988732	15	+	26627737	RPE1	viability after 18 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	2.2886676784972164	[120]	[58,266]	9	hSpCas9	negative selection	1366238
100989264	100989287	15	+	26627737	RPE1	viability after 18 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.5436579823732854	[1028]	[146,236]	-3	hSpCas9	negative selection	1366239
101009026	101009049	15	-	26627737	RPE1	viability after 18 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.6294744505169209	[844]	[389,312]	4	hSpCas9	negative selection	1366240
101010820	101010843	15	-	26627737	RPE1	viability after 18 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.5348006754747354	[385]	[60,246]	3	hSpCas9	negative selection	1366241
100973943	100973966	15	-	26627737	HeLa	viability after 8 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	-0.427748130574742	[524]	[181,142,185]	-4	hSpCas9	negative selection	1448551
100983620	100983643	15	+	26627737	HeLa	viability after 8 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.24199658330116547	[1198]	[734,539,602]	2	hSpCas9	negative selection	1448552
100988709	100988732	15	+	26627737	HeLa	viability after 8 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	-0.24983020224082875	[575]	[229,201,204]	-2	hSpCas9	negative selection	1448553
100989264	100989287	15	+	26627737	HeLa	viability after 8 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-1.0256746339534266	[716]	[175,168,121]	-8	hSpCas9	negative selection	1448554
101009026	101009049	15	-	26627737	HeLa	viability after 8 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	1.2709849735247807	[344]	[553,226,348]	8	hSpCas9	negative selection	1448555
101010820	101010843	15	-	26627737	HeLa	viability after 8 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	-0.04357366941418922	[508]	[228,295,128]	0	hSpCas9	negative selection	1448556
100973943	100973966	15	-	26627737	HeLa	viability after 12 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	-0.6882700644074731	[524]	[182,52,177]	-6	hSpCas9	negative selection	1530866
100983620	100983643	15	+	26627737	HeLa	viability after 12 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-0.2805685584282771	[1198]	[692,219,338]	-2	hSpCas9	negative selection	1530867
100988709	100988732	15	+	26627737	HeLa	viability after 12 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	-0.06607633749602837	[575]	[214,215,251]	0	hSpCas9	negative selection	1530868
100989264	100989287	15	+	26627737	HeLa	viability after 12 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.8243963498472047	[716]	[198,175,126]	-6	hSpCas9	negative selection	1530869
101009026	101009049	15	-	26627737	HeLa	viability after 12 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	1.2727214920327357	[344]	[419,161,472]	8	hSpCas9	negative selection	1530870
101010820	101010843	15	-	26627737	HeLa	viability after 12 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.47976354829250534	[508]	[398,246,241]	4	hSpCas9	negative selection	1530871
100973943	100973966	15	-	26627737	HeLa	viability after 15 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	-0.1050101702294845	[524]	[171,219,204]	-1	hSpCas9	negative selection	1613181
100983620	100983643	15	+	26627737	HeLa	viability after 15 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.3998754486742071	[1198]	[515,588,843]	3	hSpCas9	negative selection	1613182
100988709	100988732	15	+	26627737	HeLa	viability after 15 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	0.29400825963081534	[575]	[378,270,204]	2	hSpCas9	negative selection	1613183
100989264	100989287	15	+	26627737	HeLa	viability after 15 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.9532543302709081	[716]	[174,197,72]	-7	hSpCas9	negative selection	1613184
101009026	101009049	15	-	26627737	HeLa	viability after 15 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	1.379114076330928	[344]	[606,154,327]	8	hSpCas9	negative selection	1613185
101010820	101010843	15	-	26627737	HeLa	viability after 15 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.24015108039715016	[508]	[234,258,239]	2	hSpCas9	negative selection	1613186
100973943	100973966	15	-	26627737	HeLa	viability after 18 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	-0.07669698991899898	[524]	[115,190,204]	0	hSpCas9	negative selection	1695496
100983620	100983643	15	+	26627737	HeLa	viability after 18 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.3989711621253622	[1198]	[345,486,843]	3	hSpCas9	negative selection	1695497
100988709	100988732	15	+	26627737	HeLa	viability after 18 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	0.30169443244424055	[575]	[255,225,204]	2	hSpCas9	negative selection	1695498
100989264	100989287	15	+	26627737	HeLa	viability after 18 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.9095390631388128	[716]	[123,166,72]	-7	hSpCas9	negative selection	1695499
101009026	101009049	15	-	26627737	HeLa	viability after 18 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	1.424769213794362	[344]	[427,130,327]	8	hSpCas9	negative selection	1695500
101010820	101010843	15	-	26627737	HeLa	viability after 18 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.2266196408103085	[508]	[147,220,239]	2	hSpCas9	negative selection	1695501
100973943	100973966	15	-	26627737	HCT116	viability after 6 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	1.2064689251866199	[624]	[24,337]	6	hSpCas9	negative selection	1777811
100983620	100983643	15	+	26627737	HCT116	viability after 6 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.615643747195876	[1438]	[597,207]	3	hSpCas9	negative selection	1777812
100988709	100988732	15	+	26627737	HCT116	viability after 6 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	1.0244991769381466	[872]	[643,77]	5	hSpCas9	negative selection	1777813
100989264	100989287	15	+	26627737	HCT116	viability after 6 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	0.9329462767545669	[562]	[177,163]	5	hSpCas9	negative selection	1777814
101009026	101009049	15	-	26627737	HCT116	viability after 6 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	-1.514585714423311	[724]	[26,46]	-7	hSpCas9	negative selection	1777815
101010820	101010843	15	-	26627737	HCT116	viability after 6 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	-1.1721722982876202	[1101]	[150,35]	-6	hSpCas9	negative selection	1777816
100973943	100973966	15	-	26627737	HCT116	viability after 8 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	-0.41383510298453174	[266]	[135,104,90]	-5	hSpCas9	negative selection	1860126
100983620	100983643	15	+	26627737	HCT116	viability after 8 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-0.23844177469791994	[1257]	[555,518,685]	-3	hSpCas9	negative selection	1860127
100988709	100988732	15	+	26627737	HCT116	viability after 8 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	1.3502149249739823	[210]	[360,280,248]	9	hSpCas9	negative selection	1860128
100989264	100989287	15	+	26627737	HCT116	viability after 8 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.0365967660741646	[290]	[168,207,92]	0	hSpCas9	negative selection	1860129
101009026	101009049	15	-	26627737	HCT116	viability after 8 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.5966260153517751	[243]	[220,164,223]	6	hSpCas9	negative selection	1860130
101010820	101010843	15	-	26627737	HCT116	viability after 8 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	1.3685205884726663	[145]	[210,184,226]	9	hSpCas9	negative selection	1860131
100973943	100973966	15	-	26627737	HCT116	viability after 9 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.719666968627424	[624]	[99,412]	5	hSpCas9	negative selection	1942441
100983620	100983643	15	+	26627737	HCT116	viability after 9 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.43242684534737075	[1438]	[274,710]	3	hSpCas9	negative selection	1942442
100988709	100988732	15	+	26627737	HCT116	viability after 9 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	-0.746561645978157	[872]	[253,47]	-5	hSpCas9	negative selection	1942443
100989264	100989287	15	+	26627737	HCT116	viability after 9 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.22713554555494503	[562]	[233,44]	-1	hSpCas9	negative selection	1942444
101009026	101009049	15	-	26627737	HCT116	viability after 9 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.9379024119550505	[724]	[147,546]	6	hSpCas9	negative selection	1942445
101010820	101010843	15	-	26627737	HCT116	viability after 9 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	-0.14217123466635428	[1101]	[312,229]	-1	hSpCas9	negative selection	1942446
100973943	100973966	15	-	26627737	HCT116	viability after 12 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	-0.090539723058472	[266]	[212,81,91]	-1	hSpCas9	negative selection	2024756
100983620	100983643	15	+	26627737	HCT116	viability after 12 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-0.3326909668301963	[1257]	[727,481,345]	-4	hSpCas9	negative selection	2024757
100988709	100988732	15	+	26627737	HCT116	viability after 12 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	1.2176871580341087	[210]	[223,230,320]	8	hSpCas9	negative selection	2024758
100989264	100989287	15	+	26627737	HCT116	viability after 12 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	0.7064494107946284	[290]	[278,164,299]	6	hSpCas9	negative selection	2024759
101009026	101009049	15	-	26627737	HCT116	viability after 12 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.8092189238446104	[243]	[117,288,277]	7	hSpCas9	negative selection	2024760
101010820	101010843	15	-	26627737	HCT116	viability after 12 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	1.3477542933752793	[145]	[201,225,157]	9	hSpCas9	negative selection	2024761
100973943	100973966	15	-	26627737	HCT116	viability after 15 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.06130337281503313	[266]	[361,101,41]	0	hSpCas9	negative selection	2107071
100983620	100983643	15	+	26627737	HCT116	viability after 15 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-0.4534402413739831	[1257]	[646,557,393]	-5	hSpCas9	negative selection	2107072
100988709	100988732	15	+	26627737	HCT116	viability after 15 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	1.0379045729071394	[210]	[323,135,294]	8	hSpCas9	negative selection	2107073
100989264	100989287	15	+	26627737	HCT116	viability after 15 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	0.4657580255252124	[290]	[253,191,248]	4	hSpCas9	negative selection	2107074
101009026	101009049	15	-	26627737	HCT116	viability after 15 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.7144446225003139	[243]	[238,313,138]	6	hSpCas9	negative selection	2107075
101010820	101010843	15	-	26627737	HCT116	viability after 15 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	1.7356008069526818	[145]	[350,264,230]	9	hSpCas9	negative selection	2107076
100973943	100973966	15	-	26627737	HCT116	viability after 18 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.8858442293900364	[266]	[485,98,134]	7	hSpCas9	negative selection	2189386
100983620	100983643	15	+	26627737	HCT116	viability after 18 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.2020661833650399	[1257]	[841,776,463]	1	hSpCas9	negative selection	2189387
100988709	100988732	15	+	26627737	HCT116	viability after 18 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	1.7277522117858704	[210]	[367,321,323]	9	hSpCas9	negative selection	2189388
100989264	100989287	15	+	26627737	HCT116	viability after 18 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	0.5157257420580227	[290]	[116,204,284]	4	hSpCas9	negative selection	2189389
101009026	101009049	15	-	26627737	HCT116	viability after 18 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.25750894861915286	[243]	[126,129,167]	2	hSpCas9	negative selection	2189390
101010820	101010843	15	-	26627737	HCT116	viability after 18 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	1.8843409260692576	[145]	[403,113,273]	9	hSpCas9	negative selection	2189391
100924618	100924641	15	+	24336569	HL60	viability	CTGCTGCAAGGGTTGATGGCTGG	LRRK1	ENSG00000154237	-0.5701972685233949	[829]	[1182]	-5	hSpCas9	negative selection	2275114
100924657	100924680	15	-	24336569	HL60	viability	CCCACACACCAGTACATGCTGGG	LRRK1	ENSG00000154237	0.6088997795426926	[839]	[2710]	5	hSpCas9	negative selection	2275115
100924681	100924704	15	-	24336569	HL60	viability	GGACACACAGCTGACTCCTCCGG	LRRK1	ENSG00000154237	1.3855768778211932	[360]	[1995]	8	hSpCas9	negative selection	2275116
100924695	100924718	15	+	24336569	HL60	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	-0.3798621163578968	[858]	[1396]	-3	hSpCas9	negative selection	2275117
100924702	100924725	15	-	24336569	HL60	viability	AGCGTCTCCATGGCACGTTCTGG	LRRK1	ENSG00000154237	1.826603724780471	[244]	[1838]	9	hSpCas9	negative selection	2275118
100924708	100924731	15	+	24336569	HL60	viability	CGTGCCATGGAGACGCTTAACGG	LRRK1	ENSG00000154237	0.7507416853793685	[295]	[1053]	6	hSpCas9	negative selection	2275119
100973789	100973812	15	+	24336569	HL60	viability	CTTCCTCCCGCGCAGGTGCCGGG	LRRK1	ENSG00000154237	2.1915543937775195	[77]	[753]	9	hSpCas9	negative selection	2275120
100973816	100973839	15	+	24336569	HL60	viability	CGGGCGGCAAGCCGTCCACGCGG	LRRK1	ENSG00000154237	1.1566433640594445	[449]	[2122]	8	hSpCas9	negative selection	2275121
100973846	100973869	15	+	24336569	HL60	viability	ACCCTGCAGCGCGGTCCCGCAGG	LRRK1	ENSG00000154237	-0.5697055209529178	[666]	[950]	-5	hSpCas9	negative selection	2275122
100973854	100973877	15	+	24336569	HL60	viability	GCGCGGTCCCGCAGGACGGAAGG	LRRK1	ENSG00000154237	0.38116285716820775	[1229]	[3389]	3	hSpCas9	negative selection	2275123
100924618	100924641	15	+	24336569	KBM7	viability	CTGCTGCAAGGGTTGATGGCTGG	LRRK1	ENSG00000154237	0.9278464468311047	[179]	[933]	7	hSpCas9	negative selection	2342291
100924657	100924680	15	-	24336569	KBM7	viability	CCCACACACCAGTACATGCTGGG	LRRK1	ENSG00000154237	0.13999451762881154	[919]	[2764]	1	hSpCas9	negative selection	2342292
100924681	100924704	15	-	24336569	KBM7	viability	GGACACACAGCTGACTCCTCCGG	LRRK1	ENSG00000154237	1.4573941960653454	[250]	[1879]	9	hSpCas9	negative selection	2342293
100924695	100924718	15	+	24336569	KBM7	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.41455535428032153	[597]	[2173]	4	hSpCas9	negative selection	2342294
100924702	100924725	15	-	24336569	KBM7	viability	AGCGTCTCCATGGCACGTTCTGG	LRRK1	ENSG00000154237	0.9379715382295806	[345]	[1807]	7	hSpCas9	negative selection	2342295
100924708	100924731	15	+	24336569	KBM7	viability	CGTGCCATGGAGACGCTTAACGG	LRRK1	ENSG00000154237	1.351460457296718	[173]	[1210]	9	hSpCas9	negative selection	2342296
100973789	100973812	15	+	24336569	KBM7	viability	CTTCCTCCCGCGCAGGTGCCGGG	LRRK1	ENSG00000154237	0.2933335821339864	[145]	[487]	2	hSpCas9	negative selection	2342297
100973816	100973839	15	+	24336569	KBM7	viability	CGGGCGGCAAGCCGTCCACGCGG	LRRK1	ENSG00000154237	1.2987070255938018	[323]	[2173]	9	hSpCas9	negative selection	2342298
100973846	100973869	15	+	24336569	KBM7	viability	ACCCTGCAGCGCGGTCCCGCAGG	LRRK1	ENSG00000154237	0.6161262981563356	[442]	[1851]	5	hSpCas9	negative selection	2342299
100973854	100973877	15	+	24336569	KBM7	viability	GCGCGGTCCCGCAGGACGGAAGG	LRRK1	ENSG00000154237	0.2993877897748227	[1034]	[3473]	2	hSpCas9	negative selection	2342300
100949972	100949995	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGAATAGAAGTAGTGAGAGTGG	LRRK1	ENSG00000154237	-2.9880937035431487	[24,695]	[10,7]	-9	dCas9-VP64	positive selection	2472211
100949972	100949995	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGAATAGAAGTAGTGAGAGTGG	LRRK1	ENSG00000154237	0.8873452437188831	[22,11]	[13,6]	6	dCas9-VP64	positive selection	2567466
101022489	101022512	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCGTCTGTAAGATCTCCAGGAGG	LRRK1	ENSG00000154237	-0.11674684132639061	[3,4]	[3,2]	-2	hSpCas9	positive selection	3000296
101010493	101010516	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGAGGTGCAAGAATCCAGGAGG	LRRK1	ENSG00000154237	0.20368188156966055	[4,4]	[4,5]	4	hSpCas9	positive selection	3000297
101012108	101012131	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACTCAAAGAAGTTCCCCTGGG	LRRK1	ENSG00000154237	0.47551649565752163	[2,3]	[3,4]	8	hSpCas9	positive selection	3000298
101026030	101026053	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGTTGCAATCCTTTCCACACGG	LRRK1	ENSG00000154237	-0.6626734004567632	[2,2]	[0,1]	-7	hSpCas9	positive selection	3000299
101022489	101022512	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCGTCTGTAAGATCTCCAGGAGG	LRRK1	ENSG00000154237	0.5437433798903094	[3,3]	[3,4]	8	hSpCas9	positive selection	3068154
101010493	101010516	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGAGGTGCAAGAATCCAGGAGG	LRRK1	ENSG00000154237	-0.3091733211224352	[4,4]	[4,0]	-5	hSpCas9	positive selection	3068155
101012108	101012131	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACTCAAAGAAGTTCCCCTGGG	LRRK1	ENSG00000154237	-0.263743561835568	[2,2]	[3,0]	-4	hSpCas9	positive selection	3068156
101026030	101026053	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGTTGCAATCCTTTCCACACGG	LRRK1	ENSG00000154237	0.1342388235524591	[2,2]	[2,1]	2	hSpCas9	positive selection	3068157
100973873	100973896		+	24336571	A375	resistance to PLX after 7 days	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.29055044761907123	[11,11]	[13,14]	7	hSpCas9	positive selection	3125500
100989272	100989295		-	24336571	A375	resistance to PLX after 7 days	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.09119324370009751	[4,4]	[4,3]	-3	hSpCas9	positive selection	3125501
100989301	100989324		-	24336571	A375	resistance to PLX after 7 days	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	0.15738126901357083	[11,12]	[14,12]	5	hSpCas9	positive selection	3125502
100973885	100973908		-	24336571	A375	resistance to PLX after 7 days	GCGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.019210655353958717	[6,6]	[6,5]	0	hSpCas9	positive selection	3125504
100973873	100973896		+	24336571	A375	resistance to PLX after 14 days	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	1.1106874545944847	[15,13]	[15,13]	8	hSpCas9	positive selection	3183293
100989272	100989295		-	24336571	A375	resistance to PLX after 14 days	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.1808116588154587	[4,3]	[1,1]	-2	hSpCas9	positive selection	3183294
100989301	100989324		-	24336571	A375	resistance to PLX after 14 days	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	0.814261574461335	[10,11]	[9,8]	7	hSpCas9	positive selection	3183295
100973885	100973908		-	24336571	A375	resistance to PLX after 14 days	GCGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.6509701450642739	[7,7]	[4,5]	6	hSpCas9	positive selection	3183297
100973873	100973896		+	24336571	A375	viability after 7 days	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.11060205748243737	[11]	[11,11]	1	hSpCas9	negative selection	3241086
100989272	100989295		-	24336571	A375	viability after 7 days	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.20570087485364086	[5]	[4,4]	-3	hSpCas9	negative selection	3241087
100989301	100989324		-	24336571	A375	viability after 7 days	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	0.06995011584360783	[11]	[11,12]	1	hSpCas9	negative selection	3241088
100973885	100973908		-	24336571	A375	viability after 7 days	GCGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.5874420489816137	[4]	[6,6]	8	hSpCas9	negative selection	3241090
100973873	100973896		+	24336571	A375	viability after 14 days	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.405137307261003	[11]	[15,13]	5	hSpCas9	negative selection	3298879
100989272	100989295		-	24336571	A375	viability after 14 days	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.281471517999478	[5]	[4,3]	-3	hSpCas9	negative selection	3298880
100989301	100989324		-	24336571	A375	viability after 14 days	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.012116319735471587	[11]	[10,11]	0	hSpCas9	negative selection	3298881
100973885	100973908		-	24336571	A375	viability after 14 days	GCGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.824353797017717	[4]	[7,7]	9	hSpCas9	negative selection	3298883
101008995	101009018	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	-0.8354309294740174	[272,272]	[0,0]	-5	hSpCas9	positive selection	3377785
100989301	100989324	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-1.7870679079126182	[527,527]	[0,0]	-9	hSpCas9	positive selection	3377786
100989272	100989295	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.22390320990838475	[130,130]	[0,0]	1	hSpCas9	positive selection	3377787
101022489	101022512	15	-	26780180	HT29	viability (Avana library 4 designs)	CCGTCTGTAAGATCTCCAGGAGG	LRRK1	ENSG00000154237	0.571786198793684	[]	[]	2	hSpCas9	negative selection	3437876
101010493	101010516	15	-	26780180	HT29	viability (Avana library 4 designs)	GAGAGGTGCAAGAATCCAGGAGG	LRRK1	ENSG00000154237	0.37669685887542	[]	[]	1	hSpCas9	negative selection	3437877
101012107	101012130	15	+	26780180	HT29	viability (Avana library 4 designs)	GCACTCAAAGAAGTTCCCCTGGG	LRRK1	ENSG00000154237	0.632282981793842	[]	[]	2	hSpCas9	negative selection	3437878
101026030	101026053	15	-	26780180	HT29	viability (Avana library 4 designs)	GCGTTGCAATCCTTTCCACACGG	LRRK1	ENSG00000154237	0.0217845601130308	[]	[]	0	hSpCas9	negative selection	3437879
101012107	101012130	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACTCAAAGAAGTTCCCCTGGG	LRRK1	ENSG00000154237	-2.67338495981949	[]	[]	-3	hSpCas9	negative selection	3526807
101010493	101010516	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAGGTGCAAGAATCCAGGAGG	LRRK1	ENSG00000154237	-1.07595662716387	[]	[]	-1	hSpCas9	negative selection	3526808
101026030	101026053	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGTTGCAATCCTTTCCACACGG	LRRK1	ENSG00000154237	2.16519282085207	[]	[]	3	hSpCas9	negative selection	3526809
101022489	101022512	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCGTCTGTAAGATCTCCAGGAGG	LRRK1	ENSG00000154237	-1.58457997798449	[]	[]	-2	hSpCas9	negative selection	3526810
101021137	101021160	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCTTCAGTAGGCAAACCGAGG	LRRK1	ENSG00000154237	-0.483192467356825	[]	[]	0	hSpCas9	negative selection	3526811
101027356	101027379	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCAGCGACTGGCAGGGCGG	LRRK1	ENSG00000154237	4.86077970234939	[]	[]	8	hSpCas9	negative selection	3526812
101012107	101012130	15	+	26780180	A375	viability (Avana lentiGuide)	GCACTCAAAGAAGTTCCCCTGGG	LRRK1	ENSG00000154237	-1.02480913877206	[]	[]	-2	hSpCas9	negative selection	3635466
101010493	101010516	15	-	26780180	A375	viability (Avana lentiGuide)	GAGAGGTGCAAGAATCCAGGAGG	LRRK1	ENSG00000154237	11.123370931839	[]	[]	7	hSpCas9	negative selection	3635467
101026030	101026053	15	-	26780180	A375	viability (Avana lentiGuide)	GCGTTGCAATCCTTTCCACACGG	LRRK1	ENSG00000154237	2.51959830018598	[]	[]	2	hSpCas9	negative selection	3635468
101022489	101022512	15	-	26780180	A375	viability (Avana lentiGuide)	CCGTCTGTAAGATCTCCAGGAGG	LRRK1	ENSG00000154237	0.709860581877445	[]	[]	0	hSpCas9	negative selection	3635469
101021137	101021160	15	-	26780180	A375	viability (Avana lentiGuide)	GCTCTTCAGTAGGCAAACCGAGG	LRRK1	ENSG00000154237	4.66731397111416	[]	[]	4	hSpCas9	negative selection	3635470
101027356	101027379	15	+	26780180	A375	viability (Avana lentiGuide)	GCTGCCAGCGACTGGCAGGGCGG	LRRK1	ENSG00000154237	8.18355141988691	[]	[]	6	hSpCas9	negative selection	3635471
101012107	101012130	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACTCAAAGAAGTTCCCCTGGG	LRRK1	ENSG00000154237	-0.23542884194163502	[5]	[2,4]	-4	hSpCas9	positive selection	3744125
101010493	101010516	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAGGTGCAAGAATCCAGGAGG	LRRK1	ENSG00000154237	-0.2025516718103951	[5]	[5,4]	-3	hSpCas9	positive selection	3744126
101026030	101026053	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGTTGCAATCCTTTCCACACGG	LRRK1	ENSG00000154237	0.3233362984268996	[4]	[6,3]	8	hSpCas9	positive selection	3744127
101022489	101022512	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCGTCTGTAAGATCTCCAGGAGG	LRRK1	ENSG00000154237	0.08662776912205722	[5]	[5,5]	2	hSpCas9	positive selection	3744128
101021137	101021160	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCTTCAGTAGGCAAACCGAGG	LRRK1	ENSG00000154237	0.058219589931272034	[5]	[5,5]	1	hSpCas9	positive selection	3744129
101027356	101027379	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCAGCGACTGGCAGGGCGG	LRRK1	ENSG00000154237	0.3085449769004538	[3]	[5,4]	8	hSpCas9	positive selection	3744130
101012107	101012130	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACTCAAAGAAGTTCCCCTGGG	LRRK1	ENSG00000154237	0.06345498554079557	[5]	[4,4]	1	hSpCas9	positive selection	3852732
101010493	101010516	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAGGTGCAAGAATCCAGGAGG	LRRK1	ENSG00000154237	-0.6756074683056361	[6]	[3,3]	-7	hSpCas9	positive selection	3852733
101026030	101026053	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGTTGCAATCCTTTCCACACGG	LRRK1	ENSG00000154237	0.3573584634917214	[4]	[5,4]	9	hSpCas9	positive selection	3852734
101022489	101022512	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCGTCTGTAAGATCTCCAGGAGG	LRRK1	ENSG00000154237	-0.040604588035026416	[5]	[4,4]	0	hSpCas9	positive selection	3852735
101021137	101021160	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCTTCAGTAGGCAAACCGAGG	LRRK1	ENSG00000154237	0.001463328886696813	[6]	[6,3]	0	hSpCas9	positive selection	3852736
101027356	101027379	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCAGCGACTGGCAGGGCGG	LRRK1	ENSG00000154237	-0.08044226718065545	[4]	[3,3]	-1	hSpCas9	positive selection	3852737
100973873	100973896	15	+	26780180	A375	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	1.30941146314112	[]	[]	7	hSpCas9	negative selection	3958376
100989272	100989295	15	-	26780180	A375	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	1.32160168590866	[]	[]	7	hSpCas9	negative selection	3958377
100989301	100989324	15	-	26780180	A375	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	1.18860964168466	[]	[]	6	hSpCas9	negative selection	3958378
101008995	101009018	15	+	26780180	A375	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	1.28685774185322	[]	[]	7	hSpCas9	negative selection	3958379
100973821	100973844	15	+	26780180	A375	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	0.0171275576350274	[]	[]	0	hSpCas9	negative selection	3958380
101009026	101009049	15	-	26780180	A375	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.943448511065687	[]	[]	4	hSpCas9	negative selection	3958381
100973873	100973896	15	+	26780180	HT29	viability (GeCKOv2 library)	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	1.07183491457297	[]	[]	5	hSpCas9	negative selection	4066342
100989272	100989295	15	-	26780180	HT29	viability (GeCKOv2 library)	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.917944239987327	[]	[]	4	hSpCas9	negative selection	4066343
100989301	100989324	15	-	26780180	HT29	viability (GeCKOv2 library)	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	1.02714360826353	[]	[]	5	hSpCas9	negative selection	4066344
101008995	101009018	15	+	26780180	HT29	viability (GeCKOv2 library)	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	1.10102063262023	[]	[]	5	hSpCas9	negative selection	4066345
100973821	100973844	15	+	26780180	HT29	viability (GeCKOv2 library)	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	0.0266799357817992	[]	[]	0	hSpCas9	negative selection	4066346
101009026	101009049	15	-	26780180	HT29	viability (GeCKOv2 library)	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.86403703232014	[]	[]	3	hSpCas9	negative selection	4066347
100973873	100973896	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.4369695012355382	[2]	[1,3]	8	hSpCas9	positive selection	4149652
100989272	100989295	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.7116880994990056	[2]	[0,0]	-9	hSpCas9	positive selection	4149653
100989301	100989324	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	0.11417656004441963	[3]	[2,3]	3	hSpCas9	positive selection	4149654
100973885	100973908	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.03231813261183855	[2]	[1,2]	0	hSpCas9	positive selection	4149656
100973873	100973896	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.01517562238585668	[4]	[3,1,3,0]	0	hSpCas9	positive selection	4213674
100989272	100989295	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.416541620328108	[2]	[2,2,2,0]	3	hSpCas9	positive selection	4213675
100989301	100989324	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	0.7778007182933819	[4]	[3,0,4,3]	5	hSpCas9	positive selection	4213676
100973885	100973908	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.37695455427352775	[2]	[0,2,4,0]	3	hSpCas9	positive selection	4213678
101009026	101009049	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	-0.04779255359442791	[3]	[3,1]	-1	hSpCas9	positive selection	4281123
100973873	100973896	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	-0.13477212615531592	[3]	[2,1]	-3	hSpCas9	positive selection	4281124
100973821	100973844	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	0.3317026227452684	[0]	[0,0]	6	hSpCas9	positive selection	4281125
101008995	101009018	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.16393762829791547	[3]	[3,2]	3	hSpCas9	positive selection	4345382
100989301	100989324	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	0.32419833319121266	[4]	[4,4]	6	hSpCas9	positive selection	4345383
100989272	100989295	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.2519136351726608	[2]	[2,2]	5	hSpCas9	positive selection	4345384
100973885	100973907	15	-	27760321	OCIAML3	viability	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.7600183634509349	[829,782]	[799,1419]	8	hSpCas9	negative selection	4415514
101027697	101027719	15	-	27760321	OCIAML3	viability	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	-0.33739724994108466	[1222,1095]	[570,906]	-4	hSpCas9	negative selection	4415515
100988771	100988793	15	-	27760321	OCIAML3	viability	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	0.40525455535860144	[318,242]	[250,337]	5	hSpCas9	negative selection	4415516
101009026	101009048	15	-	27760321	OCIAML3	viability	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.680456521523314	[984,812]	[799,1540]	7	hSpCas9	negative selection	4415517
100973885	100973907	15	-	27760321	OCIAML2	viability	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.3608721280092798	[829,782]	[813,870]	5	hSpCas9	negative selection	4498977
101027697	101027719	15	-	27760321	OCIAML2	viability	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	-0.1685123729094784	[1222,1095]	[707,998]	-2	hSpCas9	negative selection	4498978
100988771	100988793	15	-	27760321	OCIAML2	viability	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	-0.13293085585951026	[318,242]	[146,282]	-2	hSpCas9	negative selection	4498979
101009026	101009048	15	-	27760321	OCIAML2	viability	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.5059546160448714	[984,812]	[835,1280]	7	hSpCas9	negative selection	4498980
100973885	100973907	15	-	27760321	MV411	viability	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.6302645755100437	[829,782]	[963,614]	4	hSpCas9	negative selection	4582440
101027697	101027719	15	-	27760321	MV411	viability	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	0.24092118825331954	[1222,1095]	[1052,677]	1	hSpCas9	negative selection	4582441
100988771	100988793	15	-	27760321	MV411	viability	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	0.7664931455816167	[318,242]	[286,351]	5	hSpCas9	negative selection	4582442
101009026	101009048	15	-	27760321	MV411	viability	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.3177701407185971	[984,812]	[556,1004]	2	hSpCas9	negative selection	4582443
100973885	100973907	15	-	27760321	HL60	viability	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.32909037753515713	[829,782]	[839,815]	4	hSpCas9	negative selection	4665903
101027697	101027719	15	-	27760321	HL60	viability	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	-0.34909652258025914	[1222,1095]	[682,805]	-4	hSpCas9	negative selection	4665904
100988771	100988793	15	-	27760321	HL60	viability	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	-0.22115194460350196	[318,242]	[207,181]	-2	hSpCas9	negative selection	4665905
101009026	101009048	15	-	27760321	HL60	viability	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.11115886060256264	[984,812]	[824,751]	1	hSpCas9	negative selection	4665906
100973885	100973907	15	-	27760321	HT1080	viability	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	1.4424907916412368	[782,610]	[778,727]	7	hSpCas9	negative selection	4749366
101027697	101027719	15	-	27760321	HT1080	viability	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	-0.2587110021459482	[1095,854]	[130,536]	-1	hSpCas9	negative selection	4749367
100988771	100988793	15	-	27760321	HT1080	viability	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	2.96267512027908	[242,189]	[533,823]	9	hSpCas9	negative selection	4749368
101009026	101009048	15	-	27760321	HT1080	viability	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	-1.5717176295913806	[812,634]	[44,153]	-5	hSpCas9	negative selection	4749369
100973885	100973907	15	-	27760321	HT29	viability after 7 days	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.4698529506972602	[782,610]	[1493,1066,1197]	7	hSpCas9	negative selection	4832829
101027697	101027719	15	-	27760321	HT29	viability after 7 days	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	-0.27508404856699165	[1095,854]	[1185,1186,764]	-4	hSpCas9	negative selection	4832830
100988771	100988793	15	-	27760321	HT29	viability after 7 days	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	-0.19278249826477178	[242,189]	[502,168,99]	-3	hSpCas9	negative selection	4832831
101009026	101009048	15	-	27760321	HT29	viability after 7 days	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.23413673777416277	[812,634]	[1046,836,1382]	3	hSpCas9	negative selection	4832832
100973885	100973907	15	-	27760321	HT29	viability after 25 days	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.528061165550425	[782,610]	[1093,855,1537]	6	hSpCas9	negative selection	4916292
101027697	101027719	15	-	27760321	HT29	viability after 25 days	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	-0.266897662370041	[1095,854]	[1009,817,946]	-3	hSpCas9	negative selection	4916293
100988771	100988793	15	-	27760321	HT29	viability after 25 days	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	0.3088231420052731	[242,189]	[309,326,278]	3	hSpCas9	negative selection	4916294
101009026	101009048	15	-	27760321	HT29	viability after 25 days	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.5541019309200284	[812,634]	[922,1309,1452]	6	hSpCas9	negative selection	4916295
100973885	100973907	15	-	27760321	HT29	viability after 22 days	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.4036784118298167	[782,610]	[1028,968,1201]	4	hSpCas9	negative selection	4999755
101027697	101027719	15	-	27760321	HT29	viability after 22 days	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	-0.040477653308646167	[1095,854]	[760,1075,1464]	0	hSpCas9	negative selection	4999756
100988771	100988793	15	-	27760321	HT29	viability after 22 days	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	1.0639413711609427	[242,189]	[606,505,453]	9	hSpCas9	negative selection	4999757
101009026	101009048	15	-	27760321	HT29	viability after 22 days	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.9033901682986789	[812,634]	[1592,1434,1668]	9	hSpCas9	negative selection	4999758
100973885	100973907	15	-	27760321	HT29	viability after 19 days	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.5342039600133643	[782,610]	[1349,1010,1122]	5	hSpCas9	negative selection	5083218
101027697	101027719	15	-	27760321	HT29	viability after 19 days	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	0.1407972525065866	[1095,854]	[1378,1075,1248]	1	hSpCas9	negative selection	5083219
100988771	100988793	15	-	27760321	HT29	viability after 19 days	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	0.3346501228526023	[242,189]	[279,199,447]	3	hSpCas9	negative selection	5083220
101009026	101009048	15	-	27760321	HT29	viability after 19 days	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.764644064919539	[812,634]	[1359,1510,1345]	7	hSpCas9	negative selection	5083221
100973885	100973907	15	-	27760321	HT29	viability after 16 days	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.5427757204032122	[782,610]	[1237,615,1576]	6	hSpCas9	negative selection	5166681
101027697	101027719	15	-	27760321	HT29	viability after 16 days	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	-0.26370107343120663	[1095,854]	[1015,1027,689]	-3	hSpCas9	negative selection	5166682
100988771	100988793	15	-	27760321	HT29	viability after 16 days	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	0.6597944107447097	[242,189]	[441,370,340]	7	hSpCas9	negative selection	5166683
101009026	101009048	15	-	27760321	HT29	viability after 16 days	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.7659430232338633	[812,634]	[1075,1060,1974]	8	hSpCas9	negative selection	5166684
100973885	100973907	15	-	27760321	HT29	viability after 13 days	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.46289885060570835	[782,610]	[1258,834,1240]	6	hSpCas9	negative selection	5250144
101027697	101027719	15	-	27760321	HT29	viability after 13 days	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	-0.10093701839659763	[1095,854]	[1111,823,1218]	-1	hSpCas9	negative selection	5250145
100988771	100988793	15	-	27760321	HT29	viability after 13 days	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	0.032231946233720055	[242,189]	[144,320,301]	0	hSpCas9	negative selection	5250146
101009026	101009048	15	-	27760321	HT29	viability after 13 days	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.7625987779964967	[812,634]	[1621,1374,1285]	8	hSpCas9	negative selection	5250147
100973885	100973907	15	-	27760321	HT29	viability after 10 days	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.35895290733168483	[782,610]	[1243,917,1178]	5	hSpCas9	negative selection	5333607
101027697	101027719	15	-	27760321	HT29	viability after 10 days	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	-0.045503124872562584	[1095,854]	[1087,1117,1328]	0	hSpCas9	negative selection	5333608
100988771	100988793	15	-	27760321	HT29	viability after 10 days	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	-0.9739036925296995	[242,189]	[134,160,117]	-8	hSpCas9	negative selection	5333609
101009026	101009048	15	-	27760321	HT29	viability after 10 days	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.8214042111268463	[812,634]	[1471,1469,1840]	9	hSpCas9	negative selection	5333610
100973885	100973907	15	-	27760321	MOLM13	viability	CGGTCTCCCCGCCTGTACGCGG	LRRK1	ENSG00000154237	0.5088262582209727	[829,782]	[761,550]	3	hSpCas9	negative selection	5417070
101027697	101027719	15	-	27760321	MOLM13	viability	GTACTGCACGTCGTCGTCCCGG	LRRK1	ENSG00000154237	0.034336636167052514	[1222,1095]	[505,807]	0	hSpCas9	negative selection	5417071
100988771	100988793	15	-	27760321	MOLM13	viability	GGGGCAAGCGCACGATGACAGG	LRRK1	ENSG00000154237	0.4924456168703422	[318,242]	[445,29]	3	hSpCas9	negative selection	5417072
101009026	101009048	15	-	27760321	MOLM13	viability	CGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.9380574903373413	[984,812]	[1002,936]	6	hSpCas9	negative selection	5417073
100919743	100919766	15	+	27661255	K562	viability	GGAACCCCGAAACCCCGTCCGGG	LRRK1	ENSG00000154237	0.010823395539793945	[1545,1489]	[1262,1187]	0	dCas9-KRAB	negative selection	5491176
100919789	100919812	15	+	27661255	K562	viability	GGAGGCAAGAGACACGAGTCGGG	LRRK1	ENSG00000154237	0.07131222571339418	[434,625]	[484,405]	2	dCas9-KRAB	negative selection	5491177
100919387	100919410	15	-	27661255	K562	viability	GGGCCGGGCGGACACACTGGCGG	LRRK1	ENSG00000154237	0.3342382247862027	[822,1016]	[909,933]	9	dCas9-KRAB	negative selection	5491178
100919390	100919413	15	-	27661255	K562	viability	GCGGGGCCGGGCGGACACACTGG	LRRK1	ENSG00000154237	-0.02152728076101984	[922,1094]	[823,763]	-1	dCas9-KRAB	negative selection	5491179
100919443	100919466	15	-	27661255	K562	viability	GGAGCGGCGCTTACCTGAGGCGG	LRRK1	ENSG00000154237	0.1623591689985725	[431,435]	[449,334]	5	dCas9-KRAB	negative selection	5491180
100919821	100919844	15	-	27661255	K562	viability	GAGGAAACCTATGGGCTCCCCGG	LRRK1	ENSG00000154237	0.04190749443479248	[644,716]	[579,540]	1	dCas9-KRAB	negative selection	5491181
101009026	101009049	15	-	27260156	BXPC3	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.41612070381811594	[715]	[875,942,999,1212]	8	hSpCas9	negative selection	5553583
100973873	100973896	15	+	27260156	BXPC3	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.23294565933836148	[565]	[670,732,694,675]	5	hSpCas9	negative selection	5553584
100973821	100973844	15	+	27260156	BXPC3	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.0617178076973293	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	5553585
101008995	101009018	15	+	27260156	BXPC3	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.05125920463679512	[679]	[628,689,772,882]	1	hSpCas9	negative selection	5617842
100989301	100989324	15	-	27260156	BXPC3	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.1162397031105935	[1311]	[959,1427,1154,1569]	-3	hSpCas9	negative selection	5617843
100989272	100989295	15	-	27260156	BXPC3	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.4011322638672699	[437]	[261,391,416,317]	-7	hSpCas9	negative selection	5617844
101009026	101009049	15	-	27260156	A673	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.3395526565019087	[715]	[1245,987,938,1204]	7	hSpCas9	negative selection	5674834
100973873	100973896	15	+	27260156	A673	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.05087716602397002	[565]	[886,706,628,607]	1	hSpCas9	negative selection	5674835
100973821	100973844	15	+	27260156	A673	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.2631622979798074	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	5674836
101008995	101009018	15	+	27260156	A673	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.3857756527838726	[679]	[959,1076,1041,1179]	8	hSpCas9	negative selection	5739093
100989301	100989324	15	-	27260156	A673	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.07546649840791653	[1311]	[1652,1532,1433,1367]	-2	hSpCas9	negative selection	5739094
100989272	100989295	15	-	27260156	A673	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.10718851595691292	[437]	[519,389,495,555]	-3	hSpCas9	negative selection	5739095
101009026	101009049	15	-	27260156	A375	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.424719219601725	[715]	[1097,1339,1242,865]	6	hSpCas9	negative selection	5796085
100973873	100973896	15	+	27260156	A375	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.3319297291591811	[565]	[835,996,718,799]	5	hSpCas9	negative selection	5796086
100973821	100973844	15	+	27260156	A375	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.2226069809400268	[1]	[0,0,0,0]	-8	hSpCas9	negative selection	5796087
101008995	101009018	15	+	27260156	A375	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.6474828845568996	[679]	[1312,1377,965,1323]	8	hSpCas9	negative selection	5860344
100989301	100989324	15	-	27260156	A375	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.18544820452508692	[1311]	[1158,1790,1163,1332]	-3	hSpCas9	negative selection	5860345
100989272	100989295	15	-	27260156	A375	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.14248376171394259	[437]	[619,354,573,307]	-2	hSpCas9	negative selection	5860346
101009026	101009049	15	-	27260156	COLO741	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.31241812291411164	[715]	[1122,1110,1167]	6	hSpCas9	negative selection	5917336
100973873	100973896	15	+	27260156	COLO741	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	-0.11933653230127497	[565]	[759,652,595]	-3	hSpCas9	negative selection	5917337
100973821	100973844	15	+	27260156	COLO741	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.3524737808476335	[1]	[0,0,0]	-9	hSpCas9	negative selection	5917338
101008995	101009018	15	+	27260156	COLO741	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.18408493204253018	[679]	[1297,925,776]	4	hSpCas9	negative selection	5981595
100989301	100989324	15	-	27260156	COLO741	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.49566920451097163	[1311]	[1577,936,1088]	-8	hSpCas9	negative selection	5981596
100989272	100989295	15	-	27260156	COLO741	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.6169865401562891	[437]	[437,311,350]	-8	hSpCas9	negative selection	5981597
101009026	101009049	15	-	27260156	CAL120	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.33494470572194557	[715]	[1583,998,861]	5	hSpCas9	negative selection	6038587
100973873	100973896	15	+	27260156	CAL120	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.09194891775825625	[565]	[1111,606,589]	1	hSpCas9	negative selection	6038588
100973821	100973844	15	+	27260156	CAL120	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.3152262340772953	[1]	[0,0,0]	-9	hSpCas9	negative selection	6038589
101008995	101009018	15	+	27260156	CAL120	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.4026110506383719	[679]	[1375,900,1116]	6	hSpCas9	negative selection	6102846
100989301	100989324	15	-	27260156	CAL120	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.15753027183329738	[1311]	[1526,1399,1472]	-2	hSpCas9	negative selection	6102847
100989272	100989295	15	-	27260156	CAL120	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.0921189418777647	[437]	[687,564,310]	-1	hSpCas9	negative selection	6102848
101009026	101009049	15	-	27260156	CADOES1	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.37621937528098937	[715]	[765,780,977,934]	6	hSpCas9	negative selection	6159838
100973873	100973896	15	+	27260156	CADOES1	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.18978576891038612	[565]	[521,563,760,552]	3	hSpCas9	negative selection	6159839
100973821	100973844	15	+	27260156	CADOES1	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.8953925876426645	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	6159840
101008995	101009018	15	+	27260156	CADOES1	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.508742169389951	[679]	[931,804,963,897]	8	hSpCas9	negative selection	6224097
100989301	100989324	15	-	27260156	CADOES1	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.25995825940756445	[1311]	[1039,1111,861,1063]	-4	hSpCas9	negative selection	6224098
100989272	100989295	15	-	27260156	CADOES1	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.09810795684387767	[437]	[599,467,387,281]	1	hSpCas9	negative selection	6224099
101009026	101009049	15	-	27260156	EWS502	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.5156181085367925	[715]	[1183,821,1182,1147]	8	hSpCas9	negative selection	6281089
100973873	100973896	15	+	27260156	EWS502	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.48085152648191515	[565]	[746,785,672,1171]	8	hSpCas9	negative selection	6281090
100973821	100973844	15	+	27260156	EWS502	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.081568668955347	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	6281091
101008995	101009018	15	+	27260156	EWS502	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.48811651956668145	[679]	[1080,864,873,1227]	8	hSpCas9	negative selection	6345348
100989301	100989324	15	-	27260156	EWS502	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.1912592182143933	[1311]	[1140,1161,1133,1453]	-3	hSpCas9	negative selection	6345349
100989272	100989295	15	-	27260156	EWS502	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.24978207228685362	[437]	[307,447,375,437]	-4	hSpCas9	negative selection	6345350
101009026	101009049	15	-	27260156	EW8	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.1935000991212955	[715]	[688,658,609,705]	3	hSpCas9	negative selection	6402340
100973873	100973896	15	+	27260156	EW8	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.2067088369446814	[565]	[588,570,456,517]	4	hSpCas9	negative selection	6402341
100973821	100973844	15	+	27260156	EW8	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.6956901434935379	[1]	[0,0,0,0]	-8	hSpCas9	negative selection	6402342
101008995	101009018	15	+	27260156	EW8	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.5948755669779697	[679]	[852,1209,616,687]	9	hSpCas9	negative selection	6466599
100989301	100989324	15	-	27260156	EW8	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.07274221803994507	[1311]	[1347,813,899,1033]	-1	hSpCas9	negative selection	6466600
100989272	100989295	15	-	27260156	EW8	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.10106081937589803	[437]	[574,188,429,339]	1	hSpCas9	negative selection	6466601
101009026	101009049	15	-	27260156	CORL105	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.46982732171438724	[715]	[1102,1063,1414,1100]	8	hSpCas9	negative selection	6523591
100973873	100973896	15	+	27260156	CORL105	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.4040760768144804	[565]	[701,743,981,1090]	7	hSpCas9	negative selection	6523592
100973821	100973844	15	+	27260156	CORL105	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.2272128118109151	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	6523593
101008995	101009018	15	+	27260156	CORL105	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.4963852560972204	[679]	[1133,1107,1152,1101]	8	hSpCas9	negative selection	6587850
100989301	100989324	15	-	27260156	CORL105	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.2839269213222897	[1311]	[1070,1306,1350,1322]	-5	hSpCas9	negative selection	6587851
100989272	100989295	15	-	27260156	CORL105	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.01913120489813297	[437]	[340,476,606,660]	0	hSpCas9	negative selection	6587852
101009026	101009049	15	-	27260156	HS294T	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.25007178694839094	[715]	[329,306,272,421]	3	hSpCas9	negative selection	6644842
100973873	100973896	15	+	27260156	HS294T	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.4459906268121589	[565]	[396,253,270,253]	6	hSpCas9	negative selection	6644843
100973821	100973844	15	+	27260156	HS294T	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	0.37212190850741855	[1]	[0,0,0,0]	5	hSpCas9	negative selection	6644844
101008995	101009018	15	+	27260156	HS294T	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.4354661340005491	[679]	[353,324,283,479]	6	hSpCas9	negative selection	6709101
100989301	100989324	15	-	27260156	HS294T	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	0.5765257369496792	[1311]	[903,725,688,677]	7	hSpCas9	negative selection	6709102
100989272	100989295	15	-	27260156	HS294T	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.32621792317801757	[437]	[125,112,129,179]	-4	hSpCas9	negative selection	6709103
101009026	101009049	15	-	27260156	HCC44	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.3615809181817401	[715]	[990,847,1246,1122]	6	hSpCas9	negative selection	6766093
100973873	100973896	15	+	27260156	HCC44	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	-0.016373298443198847	[565]	[760,379,688,749]	0	hSpCas9	negative selection	6766094
100973821	100973844	15	+	27260156	HCC44	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.1745335162055088	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	6766095
101008995	101009018	15	+	27260156	HCC44	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.5658212945316554	[679]	[1217,1088,1251,1022]	8	hSpCas9	negative selection	6830352
100989301	100989324	15	-	27260156	HCC44	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.2184342101753043	[1311]	[1364,1098,1732,1014]	-4	hSpCas9	negative selection	6830353
100989272	100989295	15	-	27260156	HCC44	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.009855291293870541	[437]	[873,431,395,320]	0	hSpCas9	negative selection	6830354
101009026	101009049	15	-	27260156	G402	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.7425831432112259	[715]	[1420,1728,1448,1261]	8	hSpCas9	negative selection	6887344
100973873	100973896	15	+	27260156	G402	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	-0.11919614443016932	[565]	[752,677,718,420]	-1	hSpCas9	negative selection	6887345
100973821	100973844	15	+	27260156	G402	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.2856599024101332	[1]	[0,0,0,0]	-8	hSpCas9	negative selection	6887346
101008995	101009018	15	+	27260156	G402	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.46692742213635086	[679]	[1032,1357,1131,1059]	6	hSpCas9	negative selection	6951603
100989301	100989324	15	-	27260156	G402	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.008827760057364076	[1311]	[2534,1645,1194,1143]	0	hSpCas9	negative selection	6951604
100989272	100989295	15	-	27260156	G402	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.43981900629115095	[437]	[411,841,909,695]	5	hSpCas9	negative selection	6951605
101009026	101009049	15	-	27260156	L33	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.26628759402902924	[715]	[790,392,592,753]	6	hSpCas9	negative selection	7008595
100973873	100973896	15	+	27260156	L33	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.11572064240391955	[565]	[578,284,365,596]	2	hSpCas9	negative selection	7008596
100973821	100973844	15	+	27260156	L33	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.18931687623787496	[1]	[0,0,0,1]	-4	hSpCas9	negative selection	7008597
101008995	101009018	15	+	27260156	L33	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.22367480219104208	[679]	[581,298,688,774]	5	hSpCas9	negative selection	7072854
100989301	100989324	15	-	27260156	L33	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.33260543033399426	[1311]	[1050,351,658,1206]	-7	hSpCas9	negative selection	7072855
100989272	100989295	15	-	27260156	L33	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.1065282727296003	[437]	[358,142,308,428]	-2	hSpCas9	negative selection	7072856
101009026	101009049	15	-	27260156	K562	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.5088864497507605	[715]	[725,1046,535,1254]	6	hSpCas9	negative selection	7129846
100973873	100973896	15	+	27260156	K562	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.44483193667770377	[565]	[885,848,516,523]	5	hSpCas9	negative selection	7129847
100973821	100973844	15	+	27260156	K562	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.8261501679237142	[1]	[0,0,0,0]	-7	hSpCas9	negative selection	7129848
101008995	101009018	15	+	27260156	K562	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.5389085008836387	[679]	[680,1155,1015,672]	7	hSpCas9	negative selection	7194105
100989301	100989324	15	-	27260156	K562	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.20622949744894292	[1311]	[1133,987,1007,921]	-3	hSpCas9	negative selection	7194106
100989272	100989295	15	-	27260156	K562	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.23819344180076818	[437]	[520,256,271,283]	-3	hSpCas9	negative selection	7194107
101009026	101009049	15	-	27260156	HT29	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.462123958919311	[715]	[1215,1371,1245,994]	8	hSpCas9	negative selection	7251097
100973873	100973896	15	+	27260156	HT29	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.15960202944678087	[565]	[719,943,684,734]	3	hSpCas9	negative selection	7251098
100973821	100973844	15	+	27260156	HT29	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.2790189480051524	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	7251099
101008995	101009018	15	+	27260156	HT29	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.42599330836983873	[679]	[1442,1045,1032,951]	8	hSpCas9	negative selection	7315356
100989301	100989324	15	-	27260156	HT29	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.10786873200454217	[1311]	[1476,1662,1684,1141]	-2	hSpCas9	negative selection	7315357
100989272	100989295	15	-	27260156	HT29	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.2873774583527745	[437]	[426,511,428,385]	-5	hSpCas9	negative selection	7315358
101009026	101009049	15	-	27260156	MHHES1	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.5029438845787989	[715]	[1355,1285,967,1005]	8	hSpCas9	negative selection	7372348
100973873	100973896	15	+	27260156	MHHES1	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.18208469215360285	[565]	[565,917,894,541]	3	hSpCas9	negative selection	7372349
100973821	100973844	15	+	27260156	MHHES1	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.1630968580950416	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	7372350
101008995	101009018	15	+	27260156	MHHES1	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.31410927358151497	[679]	[1062,1517,648,687]	6	hSpCas9	negative selection	7436607
100989301	100989324	15	-	27260156	MHHES1	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	0.07358594505484173	[1311]	[1453,1844,1995,1032]	1	hSpCas9	negative selection	7436608
100989272	100989295	15	-	27260156	MHHES1	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.14708755526526607	[437]	[526,672,300,329]	-3	hSpCas9	negative selection	7436609
101009026	101009049	15	-	27260156	MEWO	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.4007301646107365	[715]	[1032,804,843]	8	hSpCas9	negative selection	7493599
100973873	100973896	15	+	27260156	MEWO	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	-0.102822939565893	[565]	[562,438,490]	-2	hSpCas9	negative selection	7493600
100973821	100973844	15	+	27260156	MEWO	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.9037906333919228	[1]	[0,0,0]	-9	hSpCas9	negative selection	7493601
101008995	101009018	15	+	27260156	MEWO	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.4000789081618982	[679]	[827,852,834]	8	hSpCas9	negative selection	7557858
100989301	100989324	15	-	27260156	MEWO	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.10859873424496636	[1311]	[1358,1103,994]	-2	hSpCas9	negative selection	7557859
100989272	100989295	15	-	27260156	MEWO	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.3535902569347954	[437]	[370,276,323]	-6	hSpCas9	negative selection	7557860
101009026	101009049	15	-	27260156	LNCAPCLONEFGC	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.4769931810706044	[715]	[894,834,902,981]	7	hSpCas9	negative selection	7614850
100973873	100973896	15	+	27260156	LNCAPCLONEFGC	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.3299232369045572	[565]	[645,475,903,600]	5	hSpCas9	negative selection	7614851
100973821	100973844	15	+	27260156	LNCAPCLONEFGC	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.8571017168614112	[1]	[0,0,0,0]	-8	hSpCas9	negative selection	7614852
101008995	101009018	15	+	27260156	LNCAPCLONEFGC	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.4661190046271929	[679]	[767,773,1202,716]	7	hSpCas9	negative selection	7679109
100989301	100989324	15	-	27260156	LNCAPCLONEFGC	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.20469965412277014	[1311]	[1058,829,1218,1056]	-3	hSpCas9	negative selection	7679110
100989272	100989295	15	-	27260156	LNCAPCLONEFGC	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.30335572510788156	[437]	[484,510,517,446]	5	hSpCas9	negative selection	7679111
101009026	101009049	15	-	27260156	PANC0327	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.3421221949712555	[715]	[1165,491,900,735]	5	hSpCas9	negative selection	7736101
100973873	100973896	15	+	27260156	PANC0327	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	-0.4162987151499966	[565]	[330,332,481,362]	-6	hSpCas9	negative selection	7736102
100973821	100973844	15	+	27260156	PANC0327	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.8290241986648574	[1]	[0,0,0,0]	-8	hSpCas9	negative selection	7736103
101008995	101009018	15	+	27260156	PANC0327	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.325643719913827	[679]	[777,678,945,636]	5	hSpCas9	negative selection	7800360
100989301	100989324	15	-	27260156	PANC0327	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	0.35667423599023684	[1311]	[1556,1273,957,2211]	5	hSpCas9	negative selection	7800361
100989272	100989295	15	-	27260156	PANC0327	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.23037636907890566	[437]	[534,238,440,644]	3	hSpCas9	negative selection	7800362
101009026	101009049	15	-	27260156	NCIH2009	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.502644866272795	[715]	[1661,1137,1502]	7	hSpCas9	negative selection	7857352
100973873	100973896	15	+	27260156	NCIH2009	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.1465757099991552	[565]	[1179,643,864]	2	hSpCas9	negative selection	7857353
100973821	100973844	15	+	27260156	NCIH2009	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.7029693363496463	[1]	[0,1,1]	-7	hSpCas9	negative selection	7857354
101008995	101009018	15	+	27260156	NCIH2009	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.4708514108061794	[679]	[1512,1411,1059]	6	hSpCas9	negative selection	7921611
100989301	100989324	15	-	27260156	NCIH2009	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.19293805858606294	[1311]	[1950,1535,1390]	-3	hSpCas9	negative selection	7921612
100989272	100989295	15	-	27260156	NCIH2009	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.2553321841432785	[437]	[655,804,712]	3	hSpCas9	negative selection	7921613
101009026	101009049	15	-	27260156	NCIH1373	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	1.043136231763445	[715]	[2222,1653,836,530]	9	hSpCas9	negative selection	7978603
100973873	100973896	15	+	27260156	NCIH1373	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.981357001784082	[565]	[1619,1092,751,432]	8	hSpCas9	negative selection	7978604
100973821	100973844	15	+	27260156	NCIH1373	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.41989036405288616	[1]	[0,0,0,0]	-4	hSpCas9	negative selection	7978605
101008995	101009018	15	+	27260156	NCIH1373	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.3531807795557489	[679]	[1239,878,811,266]	3	hSpCas9	negative selection	8042862
100989301	100989324	15	-	27260156	NCIH1373	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	0.013895749721765771	[1311]	[1698,1047,1571,447]	0	hSpCas9	negative selection	8042863
100989272	100989295	15	-	27260156	NCIH1373	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.12017810405888099	[437]	[410,347,667,97]	-1	hSpCas9	negative selection	8042864
101009026	101009049	15	-	27260156	PATU8902	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.38014867214035075	[715]	[1017,1536,1002,1758]	4	hSpCas9	negative selection	8099854
100973873	100973896	15	+	27260156	PATU8902	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.40294736797418645	[565]	[1344,1025,939,848]	4	hSpCas9	negative selection	8099855
100973821	100973844	15	+	27260156	PATU8902	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.197557463276775	[1]	[0,0,0,1]	-8	hSpCas9	negative selection	8099856
101008995	101009018	15	+	27260156	PATU8902	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.7165751075752538	[679]	[1594,1328,1998,1120]	7	hSpCas9	negative selection	8164113
100989301	100989324	15	-	27260156	PATU8902	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	0.0655483594461157	[1311]	[2686,1794,1312,1992]	0	hSpCas9	negative selection	8164114
100989272	100989295	15	-	27260156	PATU8902	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.3089525129276201	[437]	[592,510,256,687]	-3	hSpCas9	negative selection	8164115
101009026	101009049	15	-	27260156	PANC1	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.2865726120154327	[715]	[715,936,768,625]	4	hSpCas9	negative selection	8221105
100973873	100973896	15	+	27260156	PANC1	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.04578853511173592	[565]	[408,643,561,427]	0	hSpCas9	negative selection	8221106
100973821	100973844	15	+	27260156	PANC1	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.774428360376552	[1]	[0,0,0,0]	-8	hSpCas9	negative selection	8221107
101008995	101009018	15	+	27260156	PANC1	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.16394318226264903	[679]	[636,914,639,494]	2	hSpCas9	negative selection	8285364
100989301	100989324	15	-	27260156	PANC1	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.052493274845392346	[1311]	[836,1324,1021,1181]	-1	hSpCas9	negative selection	8285365
100989272	100989295	15	-	27260156	PANC1	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.021077517982617283	[437]	[313,474,468,297]	0	hSpCas9	negative selection	8285366
101009026	101009049	15	-	27260156	PANC0813	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.3683609179090145	[715]	[1367,1048,1154,810]	6	hSpCas9	negative selection	8342356
100973873	100973896	15	+	27260156	PANC0813	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.26426176078729086	[565]	[881,711,919,692]	4	hSpCas9	negative selection	8342357
100973821	100973844	15	+	27260156	PANC0813	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.38317126943584334	[1]	[0,0,0,3]	-5	hSpCas9	negative selection	8342358
101008995	101009018	15	+	27260156	PANC0813	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.5088457931629851	[679]	[1357,1065,1222,929]	7	hSpCas9	negative selection	8406615
100989301	100989324	15	-	27260156	PANC0813	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.08254051651536587	[1311]	[1502,1187,1850,1292]	-1	hSpCas9	negative selection	8406616
100989272	100989295	15	-	27260156	PANC0813	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.12929109855948914	[437]	[657,402,474,367]	-2	hSpCas9	negative selection	8406617
101009026	101009049	15	-	27260156	RDES	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.4598623123761437	[715]	[942,1062,1052,1543]	7	hSpCas9	negative selection	8463607
100973873	100973896	15	+	27260156	RDES	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.00733797439610917	[565]	[522,667,693,755]	0	hSpCas9	negative selection	8463608
100973821	100973844	15	+	27260156	RDES	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.1894203535537233	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	8463609
101008995	101009018	15	+	27260156	RDES	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.36177709881870357	[679]	[824,936,1208,1082]	6	hSpCas9	negative selection	8527866
100989301	100989324	15	-	27260156	RDES	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.1317491457179214	[1311]	[1014,1372,1585,1617]	-2	hSpCas9	negative selection	8527867
100989272	100989295	15	-	27260156	RDES	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.25688927851341076	[437]	[358,357,523,461]	-4	hSpCas9	negative selection	8527868
101009026	101009049	15	-	27260156	PC3	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.3263265999892374	[715]	[636,886,1121,1042]	7	hSpCas9	negative selection	8584858
100973873	100973896	15	+	27260156	PC3	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	-0.2280026169965194	[565]	[273,617,956,293]	-5	hSpCas9	negative selection	8584859
100973821	100973844	15	+	27260156	PC3	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.9424665231552556	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	8584860
101008995	101009018	15	+	27260156	PC3	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.08218497612739595	[679]	[455,795,1146,674]	1	hSpCas9	negative selection	8649117
100989301	100989324	15	-	27260156	PC3	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.3547402323455129	[1311]	[654,750,2132,1063]	-7	hSpCas9	negative selection	8649118
100989272	100989295	15	-	27260156	PC3	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.1609440564932679	[437]	[261,614,636,547]	3	hSpCas9	negative selection	8649119
101009026	101009049	15	-	27260156	PATU8988T	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.20661960169142757	[715]	[672,846,730,960]	3	hSpCas9	negative selection	8706109
100973873	100973896	15	+	27260156	PATU8988T	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	-0.14091089425586217	[565]	[472,441,605,452]	-2	hSpCas9	negative selection	8706110
100973821	100973844	15	+	27260156	PATU8988T	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.9504748017735896	[1]	[0,0,0,0]	-8	hSpCas9	negative selection	8706111
101008995	101009018	15	+	27260156	PATU8988T	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.31631551438871364	[679]	[745,869,715,957]	5	hSpCas9	negative selection	8770368
100989301	100989324	15	-	27260156	PATU8988T	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.1419424170238568	[1311]	[1133,1033,1093,1338]	-2	hSpCas9	negative selection	8770369
100989272	100989295	15	-	27260156	PATU8988T	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.10168353945444214	[437]	[336,490,316,446]	-2	hSpCas9	negative selection	8770370
101009026	101009049	15	-	27260156	T47D	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.2705841146916166	[715]	[902,995,1019,1108]	6	hSpCas9	negative selection	8827360
100973873	100973896	15	+	27260156	T47D	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.15185053539812632	[565]	[705,815,681,718]	3	hSpCas9	negative selection	8827361
100973821	100973844	15	+	27260156	T47D	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.2201891943612022	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	8827362
101008995	101009018	15	+	27260156	T47D	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.2550129801354375	[679]	[1047,862,869,1010]	5	hSpCas9	negative selection	8891619
100989301	100989324	15	-	27260156	T47D	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.12198423625881438	[1311]	[1405,1260,1409,1557]	-3	hSpCas9	negative selection	8891620
100989272	100989295	15	-	27260156	T47D	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.04987604626588926	[437]	[461,443,460,612]	-1	hSpCas9	negative selection	8891621
101009026	101009049	15	-	27260156	SU8686	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.5656622742462446	[715]	[1090,850,1060,1244]	8	hSpCas9	negative selection	8948611
100973873	100973896	15	+	27260156	SU8686	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.3475914178077338	[565]	[603,604,839,854]	6	hSpCas9	negative selection	8948612
100973821	100973844	15	+	27260156	SU8686	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.6345296763298549	[1]	[1,0,0,0]	-7	hSpCas9	negative selection	8948613
101008995	101009018	15	+	27260156	SU8686	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.37990632878918906	[679]	[723,898,816,1113]	6	hSpCas9	negative selection	9012870
100989301	100989324	15	-	27260156	SU8686	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.27166694565742855	[1311]	[925,1016,1130,1288]	-4	hSpCas9	negative selection	9012871
100989272	100989295	15	-	27260156	SU8686	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.06452271296762238	[437]	[431,322,402,527]	-1	hSpCas9	negative selection	9012872
101009026	101009049	15	-	27260156	SKES1	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.3873591227089387	[715]	[1317,1019,918,576]	7	hSpCas9	negative selection	9069862
100973873	100973896	15	+	27260156	SKES1	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	0.08279705326499776	[565]	[665,560,608,558]	1	hSpCas9	negative selection	9069863
100973821	100973844	15	+	27260156	SKES1	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.9924535729692447	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	9069864
101008995	101009018	15	+	27260156	SKES1	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.2997122096580056	[679]	[792,906,817,817]	6	hSpCas9	negative selection	9134121
100989301	100989324	15	-	27260156	SKES1	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.2461375070406262	[1311]	[1002,1064,1385,944]	-5	hSpCas9	negative selection	9134122
100989272	100989295	15	-	27260156	SKES1	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.10577620715239541	[437]	[541,498,386,241]	-2	hSpCas9	negative selection	9134123
101009026	101009049	15	-	27260156	TOV112D	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.4133235050885532	[715]	[776,1407,812,917]	7	hSpCas9	negative selection	9191113
100973873	100973896	15	+	27260156	TOV112D	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	-0.06764957778855174	[565]	[549,857,562,277]	-1	hSpCas9	negative selection	9191114
100973821	100973844	15	+	27260156	TOV112D	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.14125609854053955	[1]	[0,4,0,0]	-3	hSpCas9	negative selection	9191115
101008995	101009018	15	+	27260156	TOV112D	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.196206700434291	[679]	[830,1004,585,757]	4	hSpCas9	negative selection	9255372
100989301	100989324	15	-	27260156	TOV112D	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	0.08268944894035779	[1311]	[1307,1447,1649,1170]	1	hSpCas9	negative selection	9255373
100989272	100989295	15	-	27260156	TOV112D	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.0118384579752812	[437]	[658,607,277,260]	0	hSpCas9	negative selection	9255374
101009026	101009049	15	-	27260156	TC71	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.19183307138122918	[715]	[785,817,1000,900]	5	hSpCas9	negative selection	9312364
100973873	100973896	15	+	27260156	TC71	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	-0.02507248308360238	[565]	[690,577,523,591]	0	hSpCas9	negative selection	9312365
100973821	100973844	15	+	27260156	TC71	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-1.1001916311946562	[1]	[0,0,0,0]	-9	hSpCas9	negative selection	9312366
101008995	101009018	15	+	27260156	TC71	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.2758977467829643	[679]	[900,880,827,923]	6	hSpCas9	negative selection	9376623
100989301	100989324	15	-	27260156	TC71	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.13686526151759137	[1311]	[1328,1291,1228,1265]	-4	hSpCas9	negative selection	9376624
100989272	100989295	15	-	27260156	TC71	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	-0.09305017938742671	[437]	[447,355,494,460]	-2	hSpCas9	negative selection	9376625
101009026	101009049	15	-	27260156	TC32	viability	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.6748273899650105	[715]	[984,957,1246,1126]	9	hSpCas9	negative selection	9433615
100973873	100973896	15	+	27260156	TC32	viability	AAGGCATCCGCGCCGCGTACAGG	LRRK1	ENSG00000154237	-0.2454377492397387	[565]	[349,350,535,604]	-4	hSpCas9	negative selection	9433616
100973821	100973844	15	+	27260156	TC32	viability	GGCAAGCCGTCCACGCGGGGCGG	LRRK1	ENSG00000154237	-0.6023200098772072	[1]	[0,0,0,1]	-8	hSpCas9	negative selection	9433617
101008995	101009018	15	+	27260156	TC32	viability	GAACCTCTCCGACAACCACCTGG	LRRK1	ENSG00000154237	0.6267541376237131	[679]	[738,965,1134,1116]	9	hSpCas9	negative selection	9497874
100989301	100989324	15	-	27260156	TC32	viability	AGGACTATCCAGCAAGATGTAGG	LRRK1	ENSG00000154237	-0.21605996283584483	[1311]	[909,827,1454,1171]	-4	hSpCas9	negative selection	9497875
100989272	100989295	15	-	27260156	TC32	viability	AATAGGCCCCATGCCGAAGCAGG	LRRK1	ENSG00000154237	0.04907422217874636	[437]	[321,448,517,405]	0	hSpCas9	negative selection	9497876
100973943	100973966	15	-	27869803	HPAFII	viability after 27 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.28047343215867526	[206]	[195,78,NaN]	2	hSpCas9	negative selection	9553037
100983620	100983643	15	+	27869803	HPAFII	viability after 27 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.19119379081152355	[905]	[461,611,NaN]	1	hSpCas9	negative selection	9553038
100988709	100988732	15	+	27869803	HPAFII	viability after 27 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	0.011109815149601326	[272]	[184,110,NaN]	0	hSpCas9	negative selection	9553039
100989264	100989287	15	+	27869803	HPAFII	viability after 27 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	0.1936954134989164	[240]	[151,138,NaN]	1	hSpCas9	negative selection	9553040
101009026	101009049	15	-	27869803	HPAFII	viability after 27 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.44746287313312316	[359]	[346,183,NaN]	3	hSpCas9	negative selection	9553041
101010820	101010843	15	-	27869803	HPAFII	viability after 27 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.4926117519761842	[306]	[123,312,NaN]	4	hSpCas9	negative selection	9553042
100973943	100973966	15	-	27869803	HPAFII	viability after 15 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.626920225123557	[206]	[530,226,NaN]	7	hSpCas9	negative selection	9635486
100983620	100983643	15	+	27869803	HPAFII	viability after 15 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-0.36565214830986137	[905]	[862,688,NaN]	-4	hSpCas9	negative selection	9635487
100988709	100988732	15	+	27869803	HPAFII	viability after 15 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	-0.34973496638836227	[272]	[302,184,NaN]	-4	hSpCas9	negative selection	9635488
100989264	100989287	15	+	27869803	HPAFII	viability after 15 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	0.5183430506565532	[240]	[534,268,NaN]	6	hSpCas9	negative selection	9635489
101009026	101009049	15	-	27869803	HPAFII	viability after 15 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	-0.2459346936977297	[359]	[464,239,NaN]	-3	hSpCas9	negative selection	9635490
101010820	101010843	15	-	27869803	HPAFII	viability after 15 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	-0.16372028987013681	[306]	[251,320,NaN]	-2	hSpCas9	negative selection	9635491
100973943	100973966	15	-	27869803	ASPC1	viability after 36 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.5337743149207221	[582]	[214,410,254]	5	hSpCas9	negative selection	9717935
100983620	100983643	15	+	27869803	ASPC1	viability after 36 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.8723144681629067	[1625]	[1129,692,1238]	8	hSpCas9	negative selection	9717936
100988709	100988732	15	+	27869803	ASPC1	viability after 36 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	0.36927617474099433	[632]	[291,327,243]	3	hSpCas9	negative selection	9717937
100989264	100989287	15	+	27869803	ASPC1	viability after 36 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.6490904338040094	[825]	[182,210,160]	-6	hSpCas9	negative selection	9717938
101009026	101009049	15	-	27869803	ASPC1	viability after 36 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.8083533617163478	[725]	[414,379,509]	7	hSpCas9	negative selection	9717939
101010820	101010843	15	-	27869803	ASPC1	viability after 36 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	0.13960037804464803	[748]	[608,55,243]	1	hSpCas9	negative selection	9717940
100973943	100973966	15	-	27869803	PATU8988S	viability after 35 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.24605041147582934	[419]	[248,151,NaN]	3	hSpCas9	negative selection	9800384
100983620	100983643	15	+	27869803	PATU8988S	viability after 35 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.2743746563788034	[1497]	[815,642,NaN]	3	hSpCas9	negative selection	9800385
100988709	100988732	15	+	27869803	PATU8988S	viability after 35 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	0.10520221861985612	[653]	[424,140,NaN]	1	hSpCas9	negative selection	9800386
100989264	100989287	15	+	27869803	PATU8988S	viability after 35 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.08328842084007343	[522]	[120,276,NaN]	-1	hSpCas9	negative selection	9800387
101009026	101009049	15	-	27869803	PATU8988S	viability after 35 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.7196321000752303	[519]	[292,396,NaN]	7	hSpCas9	negative selection	9800388
101010820	101010843	15	-	27869803	PATU8988S	viability after 35 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	-0.1503622333821245	[662]	[281,198,NaN]	-1	hSpCas9	negative selection	9800389
100973943	100973966	15	-	27869803	PATU8988S	viability after 31 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.044825119060886265	[419]	[159,188,NaN]	0	hSpCas9	negative selection	9882833
100983620	100983643	15	+	27869803	PATU8988S	viability after 31 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.19804476678519656	[1497]	[726,631,NaN]	2	hSpCas9	negative selection	9882834
100988709	100988732	15	+	27869803	PATU8988S	viability after 31 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	-0.3409415803137444	[653]	[259,136,NaN]	-4	hSpCas9	negative selection	9882835
100989264	100989287	15	+	27869803	PATU8988S	viability after 31 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	0.06972045178105704	[522]	[162,289,NaN]	0	hSpCas9	negative selection	9882836
101009026	101009049	15	-	27869803	PATU8988S	viability after 31 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.7011312250590599	[519]	[238,461,NaN]	7	hSpCas9	negative selection	9882837
101010820	101010843	15	-	27869803	PATU8988S	viability after 31 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	-0.2033563455698499	[662]	[277,167,NaN]	-2	hSpCas9	negative selection	9882838
100973943	100973966	15	-	27869803	HPAFII	viability after 35 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.3868417784828869	[206]	[176,91,NaN]	2	hSpCas9	negative selection	9965282
100983620	100983643	15	+	27869803	HPAFII	viability after 35 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.22526789569586292	[905]	[284,818,NaN]	1	hSpCas9	negative selection	9965283
100988709	100988732	15	+	27869803	HPAFII	viability after 35 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	0.6470936240156667	[272]	[254,172,NaN]	4	hSpCas9	negative selection	9965284
100989264	100989287	15	+	27869803	HPAFII	viability after 35 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.5415414306468594	[240]	[80,86,NaN]	-3	hSpCas9	negative selection	9965285
101009026	101009049	15	-	27869803	HPAFII	viability after 35 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.5681910735645002	[359]	[344,185,NaN]	3	hSpCas9	negative selection	9965286
101010820	101010843	15	-	27869803	HPAFII	viability after 35 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	1.5063472859186875	[306]	[76,851,NaN]	8	hSpCas9	negative selection	9965287
100973943	100973966	15	-	27869803	HPAFII	viability after 31 days	TTTCCAGCTGGGACGCGCACTGG	LRRK1	ENSG00000154237	0.37671849664798485	[206]	[135,166,NaN]	2	hSpCas9	negative selection	10047731
100983620	100983643	15	+	27869803	HPAFII	viability after 31 days	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.31530030653805463	[905]	[345,944,NaN]	2	hSpCas9	negative selection	10047732
100988709	100988732	15	+	27869803	HPAFII	viability after 31 days	AGCTCCTGGTCCTGACGCACGGG	LRRK1	ENSG00000154237	0.13194972236671862	[272]	[142,194,NaN]	0	hSpCas9	negative selection	10047733
100989264	100989287	15	+	27869803	HPAFII	viability after 31 days	GCAATATTCCTGCTTCGGCATGG	LRRK1	ENSG00000154237	-0.36340911505853535	[240]	[96,113,NaN]	-2	hSpCas9	negative selection	10047734
101009026	101009049	15	-	27869803	HPAFII	viability after 31 days	TCGTCCGATGACTGCACGCCAGG	LRRK1	ENSG00000154237	0.39428020822776	[359]	[310,215,NaN]	3	hSpCas9	negative selection	10047735
101010820	101010843	15	-	27869803	HPAFII	viability after 31 days	CTCACCAAAGGGCAGGCCCAGGG	LRRK1	ENSG00000154237	1.1855918218974728	[306]	[154,649,NaN]	8	hSpCas9	negative selection	10047736
101021854	101021877	15	-	28162770	P31FUJ	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-0.692233823051676	[109]	[79]	-5	hSpCas9	negative selection	10186572
100988647	100988670	15	-	28162770	P31FUJ	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	0.7993564633599957	[243]	[498]	8	hSpCas9	negative selection	10186573
101022495	101022518	15	+	28162770	P31FUJ	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	0.2220363029224402	[142]	[195]	2	hSpCas9	negative selection	10186574
100924665	100924688	15	+	28162770	P31FUJ	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	0.63540792303008	[62]	[114]	7	hSpCas9	negative selection	10186575
100924695	100924718	15	+	28162770	P31FUJ	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.49651235403584515	[604]	[1002]	5	hSpCas9	negative selection	10186576
100973876	100973899	15	+	28162770	P31FUJ	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.6517205781656853	[311]	[575]	7	hSpCas9	negative selection	10186577
100973890	100973913	15	+	28162770	P31FUJ	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	0.6970367241682206	[157]	[300]	7	hSpCas9	negative selection	10186578
100983602	100983625	15	+	28162770	P31FUJ	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	0.30109713563359697	[392]	[568]	3	hSpCas9	negative selection	10186579
100983620	100983643	15	+	28162770	P31FUJ	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.1382919472768681	[149]	[193]	1	hSpCas9	negative selection	10186580
101021854	101021877	15	-	28162770	TF1	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	NaN	[NaN]	[9]	1	hSpCas9	negative selection	10355938
100988647	100988670	15	-	28162770	TF1	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	NaN	[NaN]	[240]	1	hSpCas9	negative selection	10355939
101022495	101022518	15	+	28162770	TF1	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	NaN	[NaN]	[136]	1	hSpCas9	negative selection	10355940
100924665	100924688	15	+	28162770	TF1	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10355941
100924695	100924718	15	+	28162770	TF1	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	NaN	[NaN]	[407]	1	hSpCas9	negative selection	10355942
100973876	100973899	15	+	28162770	TF1	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	NaN	[NaN]	[695]	1	hSpCas9	negative selection	10355943
100973890	100973913	15	+	28162770	TF1	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	NaN	[NaN]	[194]	1	hSpCas9	negative selection	10355944
100983602	100983625	15	+	28162770	TF1	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	NaN	[NaN]	[392]	1	hSpCas9	negative selection	10355945
100983620	100983643	15	+	28162770	TF1	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10355946
101021854	101021877	15	-	28162770	SKM1	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	0.6889602212553739	[19]	[56]	6	hSpCas9	negative selection	10525304
100988647	100988670	15	-	28162770	SKM1	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	0.29089235838392796	[42]	[92]	3	hSpCas9	negative selection	10525305
101022495	101022518	15	+	28162770	SKM1	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	-0.7950346504217363	[52]	[53]	-5	hSpCas9	negative selection	10525306
100924665	100924688	15	+	28162770	SKM1	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	0.4124635556150176	[16]	[39]	4	hSpCas9	negative selection	10525307
100924695	100924718	15	+	28162770	SKM1	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.6865476871799827	[167]	[477]	6	hSpCas9	negative selection	10525308
100973876	100973899	15	+	28162770	SKM1	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.4464871379038963	[65]	[158]	4	hSpCas9	negative selection	10525309
100973890	100973913	15	+	28162770	SKM1	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	1.0643415201824273	[32]	[121]	8	hSpCas9	negative selection	10525310
100983602	100983625	15	+	28162770	SKM1	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	-0.1885406796096592	[77]	[120]	-2	hSpCas9	negative selection	10525311
100983620	100983643	15	+	28162770	SKM1	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.21194563390133236	[20]	[42]	2	hSpCas9	negative selection	10525312
101021854	101021877	15	-	28162770	SKM1	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	0.6889602212553739	[19]	[56]	6	hSpCas9	negative selection	10694670
100988647	100988670	15	-	28162770	SKM1	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	0.29089235838392796	[42]	[92]	3	hSpCas9	negative selection	10694671
101022495	101022518	15	+	28162770	SKM1	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	-0.7950346504217363	[52]	[53]	-5	hSpCas9	negative selection	10694672
100924665	100924688	15	+	28162770	SKM1	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	0.4124635556150176	[16]	[39]	4	hSpCas9	negative selection	10694673
100924695	100924718	15	+	28162770	SKM1	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.6865476871799827	[167]	[477]	6	hSpCas9	negative selection	10694674
100973876	100973899	15	+	28162770	SKM1	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.4464871379038963	[65]	[158]	4	hSpCas9	negative selection	10694675
100973890	100973913	15	+	28162770	SKM1	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	1.0643415201824273	[32]	[121]	8	hSpCas9	negative selection	10694676
100983602	100983625	15	+	28162770	SKM1	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	-0.1885406796096592	[77]	[120]	-2	hSpCas9	negative selection	10694677
100983620	100983643	15	+	28162770	SKM1	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.21194563390133236	[20]	[42]	2	hSpCas9	negative selection	10694678
101021854	101021877	15	-	28162770	PL21	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-2.784753493120472	[94]	[5]	-9	hSpCas9	negative selection	10864036
100988647	100988670	15	-	28162770	PL21	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	0.931650778563418	[158]	[131]	7	hSpCas9	negative selection	10864037
101022495	101022518	15	+	28162770	PL21	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	0.7878164999075121	[176]	[132]	6	hSpCas9	negative selection	10864038
100924665	100924688	15	+	28162770	PL21	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	-0.7784867347181128	[66]	[16]	-5	hSpCas9	negative selection	10864039
100924695	100924718	15	+	28162770	PL21	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	-0.5957196687304547	[624]	[179]	-4	hSpCas9	negative selection	10864040
100973876	100973899	15	+	28162770	PL21	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	-0.8543081695330561	[215]	[51]	-5	hSpCas9	negative selection	10864041
100973890	100973913	15	+	28162770	PL21	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	-1.8923066342752748	[144]	[16]	-8	hSpCas9	negative selection	10864042
100983602	100983625	15	+	28162770	PL21	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	0.1857843215122501	[302]	[149]	1	hSpCas9	negative selection	10864043
100983620	100983643	15	+	28162770	PL21	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-0.7998603855106796	[67]	[16]	-5	hSpCas9	negative selection	10864044
101021854	101021877	15	-	28162770	P31FUJ	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-0.692233823051676	[109]	[79]	-5	hSpCas9	negative selection	11033402
100988647	100988670	15	-	28162770	P31FUJ	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	0.7993564633599957	[243]	[498]	8	hSpCas9	negative selection	11033403
101022495	101022518	15	+	28162770	P31FUJ	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	0.2220363029224402	[142]	[195]	2	hSpCas9	negative selection	11033404
100924665	100924688	15	+	28162770	P31FUJ	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	0.63540792303008	[62]	[114]	7	hSpCas9	negative selection	11033405
100924695	100924718	15	+	28162770	P31FUJ	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.49651235403584515	[604]	[1002]	5	hSpCas9	negative selection	11033406
100973876	100973899	15	+	28162770	P31FUJ	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.6517205781656853	[311]	[575]	7	hSpCas9	negative selection	11033407
100973890	100973913	15	+	28162770	P31FUJ	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	0.6970367241682206	[157]	[300]	7	hSpCas9	negative selection	11033408
100983602	100983625	15	+	28162770	P31FUJ	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	0.30109713563359697	[392]	[568]	3	hSpCas9	negative selection	11033409
100983620	100983643	15	+	28162770	P31FUJ	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.1382919472768681	[149]	[193]	1	hSpCas9	negative selection	11033410
101021854	101021877	15	-	28162770	OCIAML5	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-0.48169812091888153	[40]	[52]	-3	hSpCas9	negative selection	11202768
100988647	100988670	15	-	28162770	OCIAML5	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	-0.30164248884731953	[154]	[226]	-2	hSpCas9	negative selection	11202769
101022495	101022518	15	+	28162770	OCIAML5	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	0.2756889763343758	[80]	[176]	2	hSpCas9	negative selection	11202770
100924665	100924688	15	+	28162770	OCIAML5	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	-0.10204482387234437	[21]	[36]	0	hSpCas9	negative selection	11202771
100924695	100924718	15	+	28162770	OCIAML5	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.46021135398964597	[359]	[893]	4	hSpCas9	negative selection	11202772
100973876	100973899	15	+	28162770	OCIAML5	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.4840753832430662	[201]	[509]	4	hSpCas9	negative selection	11202773
100973890	100973913	15	+	28162770	OCIAML5	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	0.2726291765853175	[71]	[156]	2	hSpCas9	negative selection	11202774
100983602	100983625	15	+	28162770	OCIAML5	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	-0.13237896812962635	[251]	[414]	-1	hSpCas9	negative selection	11202775
100983620	100983643	15	+	28162770	OCIAML5	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.07238239612882613	[48]	[92]	0	hSpCas9	negative selection	11202776
101021854	101021877	15	-	28162770	EOL1	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-0.9006184266035303	[162]	[45]	-6	hSpCas9	negative selection	11372134
100988647	100988670	15	-	28162770	EOL1	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	0.27996128816295984	[246]	[157]	2	hSpCas9	negative selection	11372135
101022495	101022518	15	+	28162770	EOL1	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	0.30111112303474263	[284]	[184]	2	hSpCas9	negative selection	11372136
100924665	100924688	15	+	28162770	EOL1	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	1.2336518261003133	[112]	[139]	8	hSpCas9	negative selection	11372137
100924695	100924718	15	+	28162770	EOL1	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.3711208442824854	[1085]	[739]	3	hSpCas9	negative selection	11372138
100973876	100973899	15	+	28162770	EOL1	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.9146662600565706	[292]	[290]	7	hSpCas9	negative selection	11372139
100973890	100973913	15	+	28162770	EOL1	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	-0.6513125220433692	[157]	[52]	-5	hSpCas9	negative selection	11372140
100983602	100983625	15	+	28162770	EOL1	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	-0.07545222842946553	[467]	[233]	0	hSpCas9	negative selection	11372141
100983620	100983643	15	+	28162770	EOL1	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.05947735165664292	[101]	[55]	0	hSpCas9	negative selection	11372142
101021854	101021877	15	-	28162770	MOLM13	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-4.076431134679231	[139]	[5]	-9	hSpCas9	negative selection	11541500
100988647	100988670	15	-	28162770	MOLM13	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	0.484763200108975	[254]	[257]	3	hSpCas9	negative selection	11541501
101022495	101022518	15	+	28162770	MOLM13	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	1.135314042457708	[271]	[431]	8	hSpCas9	negative selection	11541502
100924665	100924688	15	+	28162770	MOLM13	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	1.2048549757107851	[56]	[94]	8	hSpCas9	negative selection	11541503
100924695	100924718	15	+	28162770	MOLM13	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	1.5219152632270896	[759]	[1577]	9	hSpCas9	negative selection	11541504
100973876	100973899	15	+	28162770	MOLM13	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.920881232184628	[346]	[474]	7	hSpCas9	negative selection	11541505
100973890	100973913	15	+	28162770	MOLM13	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	-0.5852219549149834	[165]	[79]	-3	hSpCas9	negative selection	11541506
100983602	100983625	15	+	28162770	MOLM13	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	0.3965843474714458	[393]	[374]	3	hSpCas9	negative selection	11541507
100983620	100983643	15	+	28162770	MOLM13	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	1.1612280433105269	[93]	[151]	8	hSpCas9	negative selection	11541508
101021854	101021877	15	-	28162770	HEL	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-2.8311923563320556	[99]	[8]	-8	hSpCas9	negative selection	11710866
100988647	100988670	15	-	28162770	HEL	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	1.2533271403970077	[185]	[283]	9	hSpCas9	negative selection	11710867
101022495	101022518	15	+	28162770	HEL	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	0.10930663191928283	[219]	[151]	0	hSpCas9	negative selection	11710868
100924665	100924688	15	+	28162770	HEL	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	-2.772298667278487	[63]	[5]	-8	hSpCas9	negative selection	11710869
100924695	100924718	15	+	28162770	HEL	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.6899156253684235	[721]	[745]	6	hSpCas9	negative selection	11710870
100973876	100973899	15	+	28162770	HEL	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.7926342624834157	[273]	[303]	7	hSpCas9	negative selection	11710871
100973890	100973913	15	+	28162770	HEL	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	-2.228746427476963	[160]	[21]	-8	hSpCas9	negative selection	11710872
100983602	100983625	15	+	28162770	HEL	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	-0.19053656884782738	[350]	[196]	-1	hSpCas9	negative selection	11710873
100983620	100983643	15	+	28162770	HEL	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.3174980030721589	[108]	[86]	2	hSpCas9	negative selection	11710874
101021854	101021877	15	-	28162770	MV411	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-0.21199406785452224	[76]	[55]	-2	hSpCas9	negative selection	11880232
100988647	100988670	15	-	28162770	MV411	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	1.2474375507827753	[147]	[295]	9	hSpCas9	negative selection	11880233
101022495	101022518	15	+	28162770	MV411	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	0.051040337979271974	[164]	[143]	0	hSpCas9	negative selection	11880234
100924665	100924688	15	+	28162770	MV411	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	-0.46305583202224	[53]	[32]	-3	hSpCas9	negative selection	11880235
100924695	100924718	15	+	28162770	MV411	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.043904156697643026	[531]	[461]	0	hSpCas9	negative selection	11880236
100973876	100973899	15	+	28162770	MV411	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.5143764110724853	[245]	[295]	4	hSpCas9	negative selection	11880237
100973890	100973913	15	+	28162770	MV411	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	-0.35715375668731353	[110]	[72]	-3	hSpCas9	negative selection	11880238
100983602	100983625	15	+	28162770	MV411	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	-0.13266615838668128	[271]	[208]	-1	hSpCas9	negative selection	11880239
100983620	100983643	15	+	28162770	MV411	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	1.6035813610080507	[99]	[255]	9	hSpCas9	negative selection	11880240
101021854	101021877	15	-	28162770	MONOMAC1	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-0.27949900725152643	[53]	[50]	-2	hSpCas9	negative selection	12049598
100988647	100988670	15	-	28162770	MONOMAC1	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	0.942237941542574	[73]	[162]	8	hSpCas9	negative selection	12049599
101022495	101022518	15	+	28162770	MONOMAC1	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	1.3924983834514266	[104]	[315]	9	hSpCas9	negative selection	12049600
100924665	100924688	15	+	28162770	MONOMAC1	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	-0.956028747555759	[43]	[25]	-6	hSpCas9	negative selection	12049601
100924695	100924718	15	+	28162770	MONOMAC1	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.4147257130053177	[319]	[488]	4	hSpCas9	negative selection	12049602
100973876	100973899	15	+	28162770	MONOMAC1	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.7730926233583085	[121]	[238]	7	hSpCas9	negative selection	12049603
100973890	100973913	15	+	28162770	MONOMAC1	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	0.374119854136572	[69]	[103]	4	hSpCas9	negative selection	12049604
100983602	100983625	15	+	28162770	MONOMAC1	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	0.29098009757639565	[158]	[222]	3	hSpCas9	negative selection	12049605
100983620	100983643	15	+	28162770	MONOMAC1	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-0.020159084975474473	[45]	[51]	0	hSpCas9	negative selection	12049606
101021854	101021877	15	-	28162770	OCIAML2	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-2.055592325963317	[17]	[23]	-8	hSpCas9	negative selection	12218964
100988647	100988670	15	-	28162770	OCIAML2	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	-0.0066827254823711435	[28]	[159]	0	hSpCas9	negative selection	12218965
101022495	101022518	15	+	28162770	OCIAML2	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	-0.9112024166281427	[37]	[111]	-6	hSpCas9	negative selection	12218966
100924665	100924688	15	+	28162770	OCIAML2	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	0.8986039844235576	[5]	[61]	8	hSpCas9	negative selection	12218967
100924695	100924718	15	+	28162770	OCIAML2	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.8498691511124012	[100]	[1008]	7	hSpCas9	negative selection	12218968
100973876	100973899	15	+	28162770	OCIAML2	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.6786848965248651	[46]	[416]	6	hSpCas9	negative selection	12218969
100973890	100973913	15	+	28162770	OCIAML2	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	0.38735116988541096	[15]	[115]	4	hSpCas9	negative selection	12218970
100983602	100983625	15	+	28162770	OCIAML2	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	-0.9122615345327181	[72]	[214]	-6	hSpCas9	negative selection	12218971
100983620	100983643	15	+	28162770	OCIAML2	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	0.35718919937515836	[9]	[70]	3	hSpCas9	negative selection	12218972
101021854	101021877	15	-	28162770	OCIAML3	viability	GCTCAGGAGGGAGCTCCCGGAGG	LRRK1	ENSG00000154237	-1.1085808131539212	[34]	[48]	-7	hSpCas9	negative selection	12388330
100988647	100988670	15	-	28162770	OCIAML3	viability	GCATCCAGTTCAGAAGCCGCTGG	LRRK1	ENSG00000154237	-0.29444735846525527	[64]	[159]	-2	hSpCas9	negative selection	12388331
101022495	101022518	15	+	28162770	OCIAML3	viability	GGAGATCTTACAGACGGGGAGGG	LRRK1	ENSG00000154237	-0.4033240787150535	[45]	[104]	-3	hSpCas9	negative selection	12388332
100924665	100924688	15	+	28162770	OCIAML3	viability	GTACTGGTGTGTGGGGCCGGAGG	LRRK1	ENSG00000154237	1.1377962487262643	[13]	[92]	8	hSpCas9	negative selection	12388333
100924695	100924718	15	+	28162770	OCIAML3	viability	TGTGTGTCCAGAACGTGCCATGG	LRRK1	ENSG00000154237	0.31517113187962553	[167]	[630]	3	hSpCas9	negative selection	12388334
100973876	100973899	15	+	28162770	OCIAML3	viability	GCATCCGCGCCGCGTACAGGCGG	LRRK1	ENSG00000154237	0.48913359497608266	[58]	[249]	4	hSpCas9	negative selection	12388335
100973890	100973913	15	+	28162770	OCIAML3	viability	TACAGGCGGGGAGACCGCGGCGG	LRRK1	ENSG00000154237	-0.6871170447156447	[31]	[59]	-5	hSpCas9	negative selection	12388336
100983602	100983625	15	+	28162770	OCIAML3	viability	GGAGCTGCCCACCGAGCCCACGG	LRRK1	ENSG00000154237	-0.6689696980053852	[78]	[149]	-5	hSpCas9	negative selection	12388337
100983620	100983643	15	+	28162770	OCIAML3	viability	CACGGATGACAACCCAGCCGTGG	LRRK1	ENSG00000154237	-1.0634929236253832	[17]	[25]	-6	hSpCas9	negative selection	12388338