Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1463
• Symbol: NCAN
• Description: neurocan

DataSource: http://genomecrispr.dkfz.de/#!/results/NCAN

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
19227644	19227667	19	-	26472758	Jiyoye	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	-0.7537608367091845	[359]	[160]	-5	hSpCas9	negative selection	106149
19226745	19226768	19	+	26472758	Jiyoye	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	-1.0386243715436576	[78]	[28]	-6	hSpCas9	negative selection	106150
19238371	19238394	19	+	26472758	Jiyoye	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-0.7795253326872655	[172]	[75]	-5	hSpCas9	negative selection	106151
19219009	19219032	19	-	26472758	Jiyoye	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-0.1920009784349836	[152]	[100]	-1	hSpCas9	negative selection	106152
19219065	19219088	19	+	26472758	Jiyoye	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	0.0889994214796187	[95]	[76]	0	hSpCas9	negative selection	106153
19224066	19224089	19	-	26472758	Jiyoye	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-0.9620584281598454	[30]	[11]	-6	hSpCas9	negative selection	106154
19224119	19224142	19	-	26472758	Jiyoye	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	-0.4859094145776144	[51]	[27]	-3	hSpCas9	negative selection	106155
19224342	19224365	19	+	26472758	Jiyoye	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	-0.4511265334408151	[280]	[154]	-3	hSpCas9	negative selection	106156
19225061	19225084	19	-	26472758	Jiyoye	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	0.8201144149007196	[171]	[228]	6	hSpCas9	negative selection	106157
19226580	19226603	19	+	26472758	Jiyoye	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-3.2481764471066805	[62]	[4]	-9	hSpCas9	negative selection	106158
19227644	19227667	19	-	26472758	KBM7	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	-0.04553260875540621	[1197,901]	[524,427]	0	hSpCas9	negative selection	297267
19226745	19226768	19	+	26472758	KBM7	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	0.11700609185666655	[268,176]	[104,117]	1	hSpCas9	negative selection	297268
19238371	19238394	19	+	26472758	KBM7	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	0.07918698239477656	[683,396]	[290,236]	0	hSpCas9	negative selection	297269
19219009	19219032	19	-	26472758	KBM7	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-0.4598931750825661	[723,452]	[198,195]	-4	hSpCas9	negative selection	297270
19219065	19219088	19	+	26472758	KBM7	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-0.36155903822658625	[308,393]	[161,102]	-3	hSpCas9	negative selection	297271
19224066	19224089	19	-	26472758	KBM7	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-0.9870693991755186	[229,147]	[42,44]	-6	hSpCas9	negative selection	297272
19224119	19224142	19	-	26472758	KBM7	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	0.5042270627424716	[155,152]	[132,76]	5	hSpCas9	negative selection	297273
19224342	19224365	19	+	26472758	KBM7	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	0.20693387695018783	[1205,954]	[661,510]	2	hSpCas9	negative selection	297274
19225061	19225084	19	-	26472758	KBM7	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	0.8620232558994589	[784,561]	[518,612]	8	hSpCas9	negative selection	297275
19226580	19226603	19	+	26472758	KBM7	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-3.966094635209862	[232,226]	[7,5]	-9	hSpCas9	negative selection	297276
19227644	19227667	19	-	26472758	Raji	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	0.17449773123213652	[377]	[98]	1	hSpCas9	negative selection	488385
19226745	19226768	19	+	26472758	Raji	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	-0.7670855825425416	[65]	[8]	-5	hSpCas9	negative selection	488386
19238371	19238394	19	+	26472758	Raji	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-0.13450506158864553	[297]	[62]	-1	hSpCas9	negative selection	488387
19219009	19219032	19	-	26472758	Raji	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-1.4353507299582593	[302]	[25]	-7	hSpCas9	negative selection	488388
19219065	19219088	19	+	26472758	Raji	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	0.06521408112966001	[242]	[58]	0	hSpCas9	negative selection	488389
19224066	19224089	19	-	26472758	Raji	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-5.011557537349908	[138]	[0]	-9	hSpCas9	negative selection	488390
19224119	19224142	19	-	26472758	Raji	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	0.176646197810713	[121]	[31]	1	hSpCas9	negative selection	488391
19224342	19224365	19	+	26472758	Raji	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	-0.4916541505592795	[617]	[101]	-4	hSpCas9	negative selection	488392
19225061	19225084	19	-	26472758	Raji	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	-0.03526853591860912	[392]	[88]	0	hSpCas9	negative selection	488393
19226580	19226603	19	+	26472758	Raji	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-4.416178420683414	[183]	[1]	-9	hSpCas9	negative selection	488394
19227644	19227667	19	-	26472758	K562	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	0.28013547790306537	[757]	[776]	2	hSpCas9	negative selection	679503
19226745	19226768	19	+	26472758	K562	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	-0.26853252813932116	[126]	[88]	-2	hSpCas9	negative selection	679504
19238371	19238394	19	+	26472758	K562	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-3.169518737216068	[436]	[40]	-8	hSpCas9	negative selection	679505
19219009	19219032	19	-	26472758	K562	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-2.028599766739969	[347]	[71]	-7	hSpCas9	negative selection	679506
19219065	19219088	19	+	26472758	K562	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-3.5925478505016963	[442]	[30]	-8	hSpCas9	negative selection	679507
19224066	19224089	19	-	26472758	K562	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-2.707752747242938	[177]	[22]	-8	hSpCas9	negative selection	679508
19224119	19224142	19	-	26472758	K562	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	-0.007120039329517658	[149]	[125]	0	hSpCas9	negative selection	679509
19224342	19224365	19	+	26472758	K562	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	-0.17708343533852833	[670]	[500]	-1	hSpCas9	negative selection	679510
19225061	19225084	19	-	26472758	K562	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	0.22052810745842555	[547]	[538]	1	hSpCas9	negative selection	679511
19226580	19226603	19	+	26472758	K562	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-2.6598700727537916	[276]	[36]	-8	hSpCas9	negative selection	679512
19216963	19216986	19	-	26627737	DLD1	viability	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.2204368975913749	[430]	[160,229,92]	2	hSpCas9	negative selection	803583
19219060	19219083	19	-	26627737	DLD1	viability	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	1.1840771993558077	[294]	[190,173,254]	9	hSpCas9	negative selection	803584
19224027	19224050	19	+	26627737	DLD1	viability	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.01209766419956071	[442]	[192,105,114]	0	hSpCas9	negative selection	803585
19224324	19224347	19	-	26627737	DLD1	viability	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.8100729308301571	[103]	[92,63,19]	7	hSpCas9	negative selection	803586
19225237	19225260	19	-	26627737	DLD1	viability	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	-0.5099799234565952	[74]	[15,31,3]	-5	hSpCas9	negative selection	803587
19226796	19226819	19	+	26627737	DLD1	viability	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.15945211066698528	[1349]	[174,345,579]	-2	hSpCas9	negative selection	803588
19216963	19216986	19	-	26627737	GBM cells	viability after 5 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.37268249687155275	[354]	[287,204]	6	hSpCas9	negative selection	885898
19219060	19219083	19	-	26627737	GBM cells	viability after 5 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.44795212175157906	[247]	[117,76]	-6	hSpCas9	negative selection	885899
19224027	19224050	19	+	26627737	GBM cells	viability after 5 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.154415627520441	[247]	[143,94]	-2	hSpCas9	negative selection	885900
19224324	19224347	19	-	26627737	GBM cells	viability after 5 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	-0.14999572559526086	[119]	[44,70]	-2	hSpCas9	negative selection	885901
19225237	19225260	19	-	26627737	GBM cells	viability after 5 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	-1.1285668615364215	[52]	[7,17]	-9	hSpCas9	negative selection	885902
19226796	19226819	19	+	26627737	GBM cells	viability after 5 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	0.2148278403224282	[624]	[412,364]	3	hSpCas9	negative selection	885903
19216963	19216986	19	-	26627737	GBM cells	viability after 13 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.2573009559620961	[354]	[259,205]	3	hSpCas9	negative selection	968213
19219060	19219083	19	-	26627737	GBM cells	viability after 13 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.8396017173718238	[247]	[115,41]	-7	hSpCas9	negative selection	968214
19224027	19224050	19	+	26627737	GBM cells	viability after 13 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.1198658419216821	[247]	[130,117]	-1	hSpCas9	negative selection	968215
19224324	19224347	19	-	26627737	GBM cells	viability after 13 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.6981204869033175	[119]	[130,84]	8	hSpCas9	negative selection	968216
19225237	19225260	19	-	26627737	GBM cells	viability after 13 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	-0.05063712287324984	[52]	[40,16]	0	hSpCas9	negative selection	968217
19226796	19226819	19	+	26627737	GBM cells	viability after 13 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	0.07871016767326555	[624]	[329,380]	1	hSpCas9	negative selection	968218
19216963	19216986	19	-	26627737	GBM cells	viability after 21 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.35750928566503615	[354]	[279,216]	3	hSpCas9	negative selection	1050528
19219060	19219083	19	-	26627737	GBM cells	viability after 21 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-1.8885369157887162	[247]	[38,33]	-8	hSpCas9	negative selection	1050529
19224027	19224050	19	+	26627737	GBM cells	viability after 21 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.2768058859557952	[247]	[117,104]	-3	hSpCas9	negative selection	1050530
19224324	19224347	19	-	26627737	GBM cells	viability after 21 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.2142930020709587	[119]	[95,56]	2	hSpCas9	negative selection	1050531
19225237	19225260	19	-	26627737	GBM cells	viability after 21 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	-0.46455890362344077	[52]	[23,17]	-4	hSpCas9	negative selection	1050532
19226796	19226819	19	+	26627737	GBM cells	viability after 21 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	0.19985123381581982	[624]	[389,389]	2	hSpCas9	negative selection	1050533
19216963	19216986	19	-	26627737	RPE1	viability after 9 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	1.0758782044376856	[961]	[695,555]	6	hSpCas9	negative selection	1132843
19219060	19219083	19	-	26627737	RPE1	viability after 9 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	1.0906021622480497	[85]	[38,80]	6	hSpCas9	negative selection	1132844
19224027	19224050	19	+	26627737	RPE1	viability after 9 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.028668648260177412	[720]	[236,200]	0	hSpCas9	negative selection	1132845
19224324	19224347	19	-	26627737	RPE1	viability after 9 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	-0.09561411853564483	[475]	[121,161]	0	hSpCas9	negative selection	1132846
19225237	19225260	19	-	26627737	RPE1	viability after 9 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	2.82194086203385	[16]	[41,31]	9	hSpCas9	negative selection	1132847
19226796	19226819	19	+	26627737	RPE1	viability after 9 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.5522577683487968	[3093]	[412,979]	-4	hSpCas9	negative selection	1132848
19216963	19216986	19	-	26627737	RPE1	viability after 12 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.9664395267151351	[961]	[403,611]	6	hSpCas9	negative selection	1215158
19219060	19219083	19	-	26627737	RPE1	viability after 12 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	2.770754810217769	[85]	[129,186]	9	hSpCas9	negative selection	1215159
19224027	19224050	19	+	26627737	RPE1	viability after 12 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.4195416059231744	[720]	[121,168]	-3	hSpCas9	negative selection	1215160
19224324	19224347	19	-	26627737	RPE1	viability after 12 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	-0.7644021220551952	[475]	[50,100]	-5	hSpCas9	negative selection	1215161
19225237	19225260	19	-	26627737	RPE1	viability after 12 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	3.4818819185990546	[16]	[34,67]	9	hSpCas9	negative selection	1215162
19226796	19226819	19	+	26627737	RPE1	viability after 12 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.7126538673760558	[3093]	[208,822]	-5	hSpCas9	negative selection	1215163
19216963	19216986	19	-	26627737	RPE1	viability after 15 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.6919093061258872	[961]	[461,417]	4	hSpCas9	negative selection	1297473
19219060	19219083	19	-	26627737	RPE1	viability after 15 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	1.8829786168945752	[85]	[104,74]	8	hSpCas9	negative selection	1297474
19224027	19224050	19	+	26627737	RPE1	viability after 15 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.24017887527130732	[720]	[218,127]	-1	hSpCas9	negative selection	1297475
19224324	19224347	19	-	26627737	RPE1	viability after 15 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.5664887218371893	[475]	[260,139]	3	hSpCas9	negative selection	1297476
19225237	19225260	19	-	26627737	RPE1	viability after 15 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	4.373696317365088	[16]	[116,82]	9	hSpCas9	negative selection	1297477
19226796	19226819	19	+	26627737	RPE1	viability after 15 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.6862257784353012	[3093]	[378,702]	-4	hSpCas9	negative selection	1297478
19216963	19216986	19	-	26627737	RPE1	viability after 18 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.653004696160749	[961]	[443,369]	4	hSpCas9	negative selection	1379788
19219060	19219083	19	-	26627737	RPE1	viability after 18 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	1.9679636549827089	[85]	[113,65]	8	hSpCas9	negative selection	1379789
19224027	19224050	19	+	26627737	RPE1	viability after 18 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.5905767576214266	[720]	[149,106]	-4	hSpCas9	negative selection	1379790
19224324	19224347	19	-	26627737	RPE1	viability after 18 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	-0.6435174995057081	[475]	[88,74]	-4	hSpCas9	negative selection	1379791
19225237	19225260	19	-	26627737	RPE1	viability after 18 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	3.354319039997552	[16]	[29,64]	9	hSpCas9	negative selection	1379792
19226796	19226819	19	+	26627737	RPE1	viability after 18 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.6774212785504958	[3093]	[349,705]	-4	hSpCas9	negative selection	1379793
19216963	19216986	19	-	26627737	HeLa	viability after 8 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.3417065340437258	[453]	[352,234,189]	3	hSpCas9	negative selection	1462103
19219060	19219083	19	-	26627737	HeLa	viability after 8 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.023160460493132584	[240]	[88,136,81]	0	hSpCas9	negative selection	1462104
19224027	19224050	19	+	26627737	HeLa	viability after 8 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.39429040720231956	[446]	[140,146,153]	-4	hSpCas9	negative selection	1462105
19224324	19224347	19	-	26627737	HeLa	viability after 8 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	-0.6788205928327404	[322]	[140,29,102]	-6	hSpCas9	negative selection	1462106
19225237	19225260	19	-	26627737	HeLa	viability after 8 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	-1.4890299440706039	[206]	[28,10,53]	-9	hSpCas9	negative selection	1462107
19226796	19226819	19	+	26627737	HeLa	viability after 8 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	0.3588217836397103	[833]	[462,398,528]	3	hSpCas9	negative selection	1462108
19216963	19216986	19	-	26627737	HeLa	viability after 12 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	-0.1067545935606266	[453]	[184,183,152]	-1	hSpCas9	negative selection	1544418
19219060	19219083	19	-	26627737	HeLa	viability after 12 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	1.043517901908193	[240]	[423,65,146]	7	hSpCas9	negative selection	1544419
19224027	19224050	19	+	26627737	HeLa	viability after 12 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.42483872853671745	[446]	[87,178,139]	-4	hSpCas9	negative selection	1544420
19224324	19224347	19	-	26627737	HeLa	viability after 12 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	-0.10051137218807144	[322]	[110,134,125]	-1	hSpCas9	negative selection	1544421
19225237	19225260	19	-	26627737	HeLa	viability after 12 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	-2.2961866776460957	[206]	[1,24,23]	-9	hSpCas9	negative selection	1544422
19226796	19226819	19	+	26627737	HeLa	viability after 12 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	0.2584437748683326	[833]	[490,271,490]	2	hSpCas9	negative selection	1544423
19216963	19216986	19	-	26627737	HeLa	viability after 15 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.48549722516479304	[453]	[237,334,198]	4	hSpCas9	negative selection	1626733
19219060	19219083	19	-	26627737	HeLa	viability after 15 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.29749390643824836	[240]	[106,53,77]	-3	hSpCas9	negative selection	1626734
19224027	19224050	19	+	26627737	HeLa	viability after 15 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	0.09977399806737633	[446]	[100,292,191]	0	hSpCas9	negative selection	1626735
19224324	19224347	19	-	26627737	HeLa	viability after 15 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.6346055675238089	[322]	[256,195,154]	5	hSpCas9	negative selection	1626736
19225237	19225260	19	-	26627737	HeLa	viability after 15 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	-1.0206401192645687	[206]	[55,31,35]	-7	hSpCas9	negative selection	1626737
19226796	19226819	19	+	26627737	HeLa	viability after 15 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	0.6092923987710213	[833]	[496,298,777]	5	hSpCas9	negative selection	1626738
19216963	19216986	19	-	26627737	HeLa	viability after 18 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.45712775779354536	[453]	[158,265,198]	4	hSpCas9	negative selection	1709048
19219060	19219083	19	-	26627737	HeLa	viability after 18 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.24965163216013153	[240]	[75,45,77]	-2	hSpCas9	negative selection	1709049
19224027	19224050	19	+	26627737	HeLa	viability after 18 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	0.10790210331994923	[446]	[75,234,191]	0	hSpCas9	negative selection	1709050
19224324	19224347	19	-	26627737	HeLa	viability after 18 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.6248610542090262	[322]	[165,166,154]	5	hSpCas9	negative selection	1709051
19225237	19225260	19	-	26627737	HeLa	viability after 18 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	-0.9035909354841053	[206]	[43,26,35]	-7	hSpCas9	negative selection	1709052
19226796	19226819	19	+	26627737	HeLa	viability after 18 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	0.613960713506279	[833]	[337,245,777]	5	hSpCas9	negative selection	1709053
19216963	19216986	19	-	26627737	HCT116	viability after 6 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	-0.18340933310848362	[592]	[181,26]	-1	hSpCas9	negative selection	1791363
19219060	19219083	19	-	26627737	HCT116	viability after 6 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	1.163653008500653	[856]	[43,443]	6	hSpCas9	negative selection	1791364
19224027	19224050	19	+	26627737	HCT116	viability after 6 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.19802199052961567	[334]	[52,41]	-1	hSpCas9	negative selection	1791365
19224324	19224347	19	-	26627737	HCT116	viability after 6 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	-2.4459370931060986	[170]	[2,5]	-8	hSpCas9	negative selection	1791366
19225237	19225260	19	-	26627737	HCT116	viability after 6 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	-4.469396422776977	[190]	[1,0]	-9	hSpCas9	negative selection	1791367
19226796	19226819	19	+	26627737	HCT116	viability after 6 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	0.9679015184889386	[1707]	[1181,162]	5	hSpCas9	negative selection	1791368
19216963	19216986	19	-	26627737	HCT116	viability after 8 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.6315149894796563	[282]	[238,268,216]	6	hSpCas9	negative selection	1873678
19219060	19219083	19	-	26627737	HCT116	viability after 8 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.8299880702194924	[371]	[57,96,188]	-8	hSpCas9	negative selection	1873679
19224027	19224050	19	+	26627737	HCT116	viability after 8 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.5500761958082004	[369]	[142,68,204]	-6	hSpCas9	negative selection	1873680
19224324	19224347	19	-	26627737	HCT116	viability after 8 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.22707180866355525	[102]	[53,72,71]	2	hSpCas9	negative selection	1873681
19225237	19225260	19	-	26627737	HCT116	viability after 8 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	-0.005984144298956995	[27]	[15,5,23]	0	hSpCas9	negative selection	1873682
19226796	19226819	19	+	26627737	HCT116	viability after 8 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.2761309632822182	[979]	[499,410,427]	-3	hSpCas9	negative selection	1873683
19216963	19216986	19	-	26627737	HCT116	viability after 9 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	-0.13201777458530528	[592]	[134,151]	-1	hSpCas9	negative selection	1955993
19219060	19219083	19	-	26627737	HCT116	viability after 9 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.9180099372354757	[856]	[38,185]	-6	hSpCas9	negative selection	1955994
19224027	19224050	19	+	26627737	HCT116	viability after 9 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.21691627329312912	[334]	[62,87]	-1	hSpCas9	negative selection	1955995
19224324	19224347	19	-	26627737	HCT116	viability after 9 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.27556905866773196	[170]	[4,94]	2	hSpCas9	negative selection	1955996
19225237	19225260	19	-	26627737	HCT116	viability after 9 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	-2.194225098056016	[190]	[4,15]	-9	hSpCas9	negative selection	1955997
19226796	19226819	19	+	26627737	HCT116	viability after 9 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.5322037150565694	[1707]	[473,189]	-4	hSpCas9	negative selection	1955998
19216963	19216986	19	-	26627737	HCT116	viability after 12 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.38298484429254576	[282]	[127,250,209]	4	hSpCas9	negative selection	2038308
19219060	19219083	19	-	26627737	HCT116	viability after 12 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.6804772127975443	[371]	[112,132,120]	-6	hSpCas9	negative selection	2038309
19224027	19224050	19	+	26627737	HCT116	viability after 12 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	0.01706993606157786	[369]	[239,176,168]	0	hSpCas9	negative selection	2038310
19224324	19224347	19	-	26627737	HCT116	viability after 12 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	1.149665014032753	[102]	[92,92,175]	8	hSpCas9	negative selection	2038311
19225237	19225260	19	-	26627737	HCT116	viability after 12 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	0.5957943666634566	[27]	[16,14,34]	5	hSpCas9	negative selection	2038312
19226796	19226819	19	+	26627737	HCT116	viability after 12 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.3837762537363172	[979]	[475,475,226]	-4	hSpCas9	negative selection	2038313
19216963	19216986	19	-	26627737	HCT116	viability after 15 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.4217525301850812	[282]	[341,169,156]	4	hSpCas9	negative selection	2120623
19219060	19219083	19	-	26627737	HCT116	viability after 15 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.48129612982259323	[371]	[81,176,190]	-5	hSpCas9	negative selection	2120624
19224027	19224050	19	+	26627737	HCT116	viability after 15 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.27956100904806397	[369]	[249,167,116]	-3	hSpCas9	negative selection	2120625
19224324	19224347	19	-	26627737	HCT116	viability after 15 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	1.0269135180394193	[102]	[128,60,171]	8	hSpCas9	negative selection	2120626
19225237	19225260	19	-	26627737	HCT116	viability after 15 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	1.961671290906486	[27]	[34,41,106]	9	hSpCas9	negative selection	2120627
19226796	19226819	19	+	26627737	HCT116	viability after 15 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.4580844870628842	[979]	[711,319,235]	-5	hSpCas9	negative selection	2120628
19216963	19216986	19	-	26627737	HCT116	viability after 18 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.3998642466691229	[282]	[121,251,161]	3	hSpCas9	negative selection	2202938
19219060	19219083	19	-	26627737	HCT116	viability after 18 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.45167228110544755	[371]	[48,143,203]	-4	hSpCas9	negative selection	2202939
19224027	19224050	19	+	26627737	HCT116	viability after 18 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.5501352875812473	[369]	[147,72,149]	-5	hSpCas9	negative selection	2202940
19224324	19224347	19	-	26627737	HCT116	viability after 18 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.5998924372302248	[102]	[30,62,135]	5	hSpCas9	negative selection	2202941
19225237	19225260	19	-	26627737	HCT116	viability after 18 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	1.28468931857237	[27]	[62,2,34]	8	hSpCas9	negative selection	2202942
19226796	19226819	19	+	26627737	HCT116	viability after 18 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	0.1498236379506701	[979]	[816,250,526]	1	hSpCas9	negative selection	2202943
19212036	19212059	19	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CCCCGGGATGCGTCCGAGCTAGG	NCAN	ENSG00000130287	-0.13172129451479866	[2556,2867,2836]	[0,0,0]	-1	hSpCas9	positive selection	2381118
19218923	19218947	19	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.17452394104758048	[2927,2995,2608]	[0,0,0]	-1	hSpCas9	positive selection	2381119
19219201	19219224	19	+	24717434	HeLa	essential genes for diphteria toxin toxicity	AGCCAACGCCACGCTACTTCTGG	NCAN	ENSG00000130287	0.01157480095761116	[2670,2086,2748]	[0,0,0]	0	hSpCas9	positive selection	2381120
19212036	19212059	19	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCCCGGGATGCGTCCGAGCTAGG	NCAN	ENSG00000130287	-0.1319260304729462	[2556,2867,2836]	[0,0,0]	-1	hSpCas9	positive selection	2382400
19212036	19212059	19	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCCCGGGATGCGTCCGAGCTAGG	NCAN	ENSG00000130287	-0.1319260304729462	[2556,2867,2836]	[0,0,0]	-1	hSpCas9	positive selection	2382401
19218923	19218947	19	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.17504666046138892	[2927,2995,2608]	[0,0,0]	-2	hSpCas9	positive selection	2382402
19218923	19218947	19	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.17504666046138892	[2927,2995,2608]	[0,0,0]	-2	hSpCas9	positive selection	2382403
19219201	19219224	19	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AGCCAACGCCACGCTACTTCTGG	NCAN	ENSG00000130287	3.674977592445207	[2670,2086,2748]	[0,0,35]	6	hSpCas9	positive selection	2382404
19219201	19219224	19	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AGCCAACGCCACGCTACTTCTGG	NCAN	ENSG00000130287	3.674977592445207	[2670,2086,2748]	[0,0,35]	6	hSpCas9	positive selection	2382405
19223002	19223025	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGGCTGAGGCAGGAGAATGG	NCAN	ENSG00000130287	-0.8896445471743792	[26,0]	[0,0]	-5	dCas9-VP64	positive selection	2422267
19220820	19220843	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCACTTTGGGAGGCTGAAGAGG	NCAN	ENSG00000130287	6.35516198632701	[126,1064]	[8429,13566]	9	dCas9-VP64	positive selection	2467119
19223002	19223025	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGGCTGAGGCAGGAGAATGG	NCAN	ENSG00000130287	0.4958448470370793	[21,20]	[10,7]	4	dCas9-VP64	positive selection	2517522
19220820	19220843	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCACTTTGGGAGGCTGAAGAGG	NCAN	ENSG00000130287	6.970706058095935	[220,255]	[14367,5508]	9	dCas9-VP64	positive selection	2562374
19227030	19227053	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATTGGTCAGATCAGCCCAGGGG	NCAN	ENSG00000130287	0.3779490750903388	[2,3]	[1,4]	7	hSpCas9	positive selection	3004769
19224056	19224079	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.04493088749583796	[4,4]	[3,2]	0	hSpCas9	positive selection	3004770
19219059	19219082	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	0.17188752955881068	[3,3]	[2,3]	3	hSpCas9	positive selection	3004771
19225238	19225261	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGGCGTCGAAGCGCTCGGCGG	NCAN	ENSG00000130287	0.6447515421054445	[2,2]	[1,5]	9	hSpCas9	positive selection	3004772
19227030	19227053	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATTGGTCAGATCAGCCCAGGGG	NCAN	ENSG00000130287	-0.4397584577838296	[2,2]	[1,0]	-6	hSpCas9	positive selection	3072627
19224056	19224079	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.09120143393021768	[4,4]	[5,0]	-1	hSpCas9	positive selection	3072628
19219059	19219082	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	0.6952968758053043	[3,3]	[3,4]	9	hSpCas9	positive selection	3072629
19225238	19225261	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGGCGTCGAAGCGCTCGGCGG	NCAN	ENSG00000130287	0.2745795368240246	[2,2]	[3,1]	5	hSpCas9	positive selection	3072630
19218924	19218947		+	24336571	A375	resistance to PLX after 7 days	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	0.005791476508088478	[14,17]	[16,15]	0	hSpCas9	positive selection	3129816
19224184	19224207		-	24336571	A375	resistance to PLX after 7 days	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.19557556165372958	[18,16]	[20,20]	6	hSpCas9	positive selection	3129819
19224052	19224075		-	24336571	A375	resistance to PLX after 7 days	CAGCGAAGGTCAGTGCATAGCGG	NCAN	ENSG00000130287	0.18412269464642456	[7,8]	[8,10]	5	hSpCas9	positive selection	3129820
19218924	19218947		+	24336571	A375	resistance to PLX after 14 days	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	0.9402752991077912	[11,12]	[11,9]	7	hSpCas9	positive selection	3187609
19224184	19224207		-	24336571	A375	resistance to PLX after 14 days	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.9286406059585373	[19,10]	[13,13]	7	hSpCas9	positive selection	3187612
19224052	19224075		-	24336571	A375	resistance to PLX after 14 days	CAGCGAAGGTCAGTGCATAGCGG	NCAN	ENSG00000130287	0.14844881000750304	[9,7]	[4,3]	1	hSpCas9	positive selection	3187613
19218924	19218947		+	24336571	A375	viability after 7 days	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	0.07484758770431676	[15]	[14,17]	1	hSpCas9	negative selection	3245402
19224184	19224207		-	24336571	A375	viability after 7 days	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	-0.06412086725667099	[19]	[18,16]	-1	hSpCas9	negative selection	3245405
19224052	19224075		-	24336571	A375	viability after 7 days	CAGCGAAGGTCAGTGCATAGCGG	NCAN	ENSG00000130287	0.057218448962280566	[8]	[7,8]	0	hSpCas9	negative selection	3245406
19218924	19218947		+	24336571	A375	viability after 14 days	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.3155217895349296	[15]	[11,12]	-4	hSpCas9	negative selection	3303195
19224184	19224207		-	24336571	A375	viability after 14 days	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	-0.2561354195174784	[19]	[19,10]	-3	hSpCas9	negative selection	3303198
19224052	19224075		-	24336571	A375	viability after 14 days	CAGCGAAGGTCAGTGCATAGCGG	NCAN	ENSG00000130287	0.12659560955843463	[8]	[9,7]	1	hSpCas9	negative selection	3303199
19224340	19224363	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	-0.3573836326693731	[195,195]	[0,0]	-2	hSpCas9	positive selection	3381082
19224055	19224078	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	0.4499712893882311	[111,111]	[0,0]	2	hSpCas9	positive selection	3381083
19224372	19224395	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.6134700216711103	[99,99]	[0,0]	3	hSpCas9	positive selection	3381084
19227030	19227053	19	-	26780180	HT29	viability (Avana library 4 designs)	CATTGGTCAGATCAGCCCAGGGG	NCAN	ENSG00000130287	0.767635501520485	[]	[]	3	hSpCas9	negative selection	3442603
19224055	19224078	19	+	26780180	HT29	viability (Avana library 4 designs)	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	1.64132876322685	[]	[]	6	hSpCas9	negative selection	3442604
19219059	19219082	19	-	26780180	HT29	viability (Avana library 4 designs)	CTTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	2.29614280267633	[]	[]	8	hSpCas9	negative selection	3442605
19225238	19225261	19	-	26780180	HT29	viability (Avana library 4 designs)	GTAGGCGTCGAAGCGCTCGGCGG	NCAN	ENSG00000130287	3.1867345119519	[]	[]	8	hSpCas9	negative selection	3442606
19225238	19225261	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGGCGTCGAAGCGCTCGGCGG	NCAN	ENSG00000130287	3.72172589014715	[]	[]	6	hSpCas9	negative selection	3533877
19224055	19224078	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.838846586597341	[]	[]	-1	hSpCas9	negative selection	3533878
19219059	19219082	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	5.3328082647423	[]	[]	8	hSpCas9	negative selection	3533879
19227030	19227053	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATTGGTCAGATCAGCCCAGGGG	NCAN	ENSG00000130287	-1.43301278371838	[]	[]	-2	hSpCas9	negative selection	3533880
19224117	19224140	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCAGCCTGTAGATGCCGAGGGG	NCAN	ENSG00000130287	3.48640501428226	[]	[]	5	hSpCas9	negative selection	3533881
19219044	19219067	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCAGCCCGAGATGCCCCTCGG	NCAN	ENSG00000130287	4.52391115558537	[]	[]	7	hSpCas9	negative selection	3533882
19225238	19225261	19	-	26780180	A375	viability (Avana lentiGuide)	GTAGGCGTCGAAGCGCTCGGCGG	NCAN	ENSG00000130287	3.05796310921676	[]	[]	3	hSpCas9	negative selection	3642536
19224055	19224078	19	+	26780180	A375	viability (Avana lentiGuide)	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	2.68739026118483	[]	[]	3	hSpCas9	negative selection	3642537
19219059	19219082	19	-	26780180	A375	viability (Avana lentiGuide)	CTTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	8.94833945546246	[]	[]	6	hSpCas9	negative selection	3642538
19227030	19227053	19	-	26780180	A375	viability (Avana lentiGuide)	CATTGGTCAGATCAGCCCAGGGG	NCAN	ENSG00000130287	-1.01964747354765	[]	[]	-1	hSpCas9	negative selection	3642539
19224117	19224140	19	-	26780180	A375	viability (Avana lentiGuide)	GGCAGCCTGTAGATGCCGAGGGG	NCAN	ENSG00000130287	6.98426135855397	[]	[]	5	hSpCas9	negative selection	3642540
19219044	19219067	19	+	26780180	A375	viability (Avana lentiGuide)	GCGCAGCCCGAGATGCCCCTCGG	NCAN	ENSG00000130287	1.12317645840898	[]	[]	1	hSpCas9	negative selection	3642541
19225238	19225261	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGGCGTCGAAGCGCTCGGCGG	NCAN	ENSG00000130287	0.19494180523903282	[4]	[5,5]	5	hSpCas9	positive selection	3751195
19224055	19224078	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.26899166929058405	[6]	[5,4]	-4	hSpCas9	positive selection	3751196
19219059	19219082	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	0.2575386907177497	[4]	[5,4]	7	hSpCas9	positive selection	3751197
19227030	19227053	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTGGTCAGATCAGCCCAGGGG	NCAN	ENSG00000130287	-0.014291476589940427	[4]	[4,3]	0	hSpCas9	positive selection	3751198
19224117	19224140	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCAGCCTGTAGATGCCGAGGGG	NCAN	ENSG00000130287	0.32919518315780594	[4]	[5,5]	8	hSpCas9	positive selection	3751199
19219044	19219067	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCAGCCCGAGATGCCCCTCGG	NCAN	ENSG00000130287	0.3269871562911183	[4]	[5,5]	8	hSpCas9	positive selection	3751200
19225238	19225261	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGGCGTCGAAGCGCTCGGCGG	NCAN	ENSG00000130287	-0.3583299794858194	[5]	[1,4]	-5	hSpCas9	positive selection	3859802
19224055	19224078	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.3208780293227094	[6]	[5,2]	-4	hSpCas9	positive selection	3859803
19219059	19219082	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	-0.0051680828460081984	[5]	[5,2]	0	hSpCas9	positive selection	3859804
19227030	19227053	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTGGTCAGATCAGCCCAGGGG	NCAN	ENSG00000130287	-0.0017034332836460275	[4]	[3,2]	0	hSpCas9	positive selection	3859805
19224117	19224140	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCAGCCTGTAGATGCCGAGGGG	NCAN	ENSG00000130287	-0.5123629153023762	[4]	[0,4]	-6	hSpCas9	positive selection	3859806
19219044	19219067	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCAGCCCGAGATGCCCCTCGG	NCAN	ENSG00000130287	0.16757563136995207	[5]	[5,4]	4	hSpCas9	positive selection	3859807
19218924	19218947	19	+	26780180	A375	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	1.42353460794067	[]	[]	7	hSpCas9	negative selection	3971121
19224184	19224207	19	-	26780180	A375	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	1.21803155490158	[]	[]	6	hSpCas9	negative selection	3971122
19224055	19224078	19	+	26780180	A375	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	1.65925678874592	[]	[]	8	hSpCas9	negative selection	3971123
19224372	19224395	19	+	26780180	A375	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	1.93043389925135	[]	[]	9	hSpCas9	negative selection	3971124
19219075	19219098	19	+	26780180	A375	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.890629331024215	[]	[]	4	hSpCas9	negative selection	3971125
19224340	19224363	19	+	26780180	A375	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	1.41476508618488	[]	[]	7	hSpCas9	negative selection	3971126
19218924	19218947	19	+	26780180	HT29	viability (GeCKOv2 library)	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	1.31869482975418	[]	[]	6	hSpCas9	negative selection	4079087
19224184	19224207	19	-	26780180	HT29	viability (GeCKOv2 library)	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	1.0638524628124	[]	[]	5	hSpCas9	negative selection	4079088
19224055	19224078	19	+	26780180	HT29	viability (GeCKOv2 library)	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	1.99230150567682	[]	[]	9	hSpCas9	negative selection	4079089
19224372	19224395	19	+	26780180	HT29	viability (GeCKOv2 library)	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	3.23980952184934	[]	[]	9	hSpCas9	negative selection	4079090
19219075	19219098	19	+	26780180	HT29	viability (GeCKOv2 library)	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	1.70825227766627	[]	[]	8	hSpCas9	negative selection	4079091
19224340	19224363	19	+	26780180	HT29	viability (GeCKOv2 library)	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	1.6707865169631	[]	[]	8	hSpCas9	negative selection	4079092
19218924	19218947	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	0.24700566301962945	[3]	[2,3]	6	hSpCas9	positive selection	4154422
19224184	19224207	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	-0.005089743279488357	[4]	[1,3]	0	hSpCas9	positive selection	4154425
19224052	19224075	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGCGAAGGTCAGTGCATAGCGG	NCAN	ENSG00000130287	0.10765563857151653	[3]	[2,1]	2	hSpCas9	positive selection	4154426
19218924	19218947	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	1.3010028978590695	[3]	[5,4,2,4]	9	hSpCas9	positive selection	4218444
19224184	19224207	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	-0.7277126265773671	[4]	[0,0,1,0]	-8	hSpCas9	positive selection	4218447
19224052	19224075	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGCGAAGGTCAGTGCATAGCGG	NCAN	ENSG00000130287	0.5212751795581189	[4]	[3,0,0,3]	3	hSpCas9	positive selection	4218448
19218924	19218947	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.09710017845443632	[3]	[2,1]	-2	hSpCas9	positive selection	4284915
19219075	19219098	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.08554837336860754	[2]	[2,1]	1	hSpCas9	positive selection	4284916
19224184	19224207	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	-0.19920011640073992	[3]	[3,0]	-4	hSpCas9	positive selection	4284917
19224340	19224363	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	-0.46254548538452755	[2]	[2,0]	-7	hSpCas9	positive selection	4349174
19224055	19224078	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	0.15558358799154184	[2]	[1,2]	3	hSpCas9	positive selection	4349175
19224372	19224395	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.22812569201018001	[4]	[2,2]	-5	hSpCas9	positive selection	4349176
19219059	19219081	19	-	27760321	OCIAML3	viability	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	-0.8494615667885107	[294,265]	[82,171]	-7	hSpCas9	negative selection	4421290
19224180	19224202	19	+	27760321	OCIAML3	viability	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.5673918543624937	[675,596]	[264,426]	-5	hSpCas9	negative selection	4421291
19224354	19224376	19	-	27760321	OCIAML3	viability	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	0.1870115985746651	[628,458]	[355,640]	2	hSpCas9	negative selection	4421292
19225186	19225208	19	-	27760321	OCIAML3	viability	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	0.1461604637972651	[501,514]	[441,441]	1	hSpCas9	negative selection	4421293
19225206	19225228	19	-	27760321	OCIAML3	viability	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	-0.3442404350213871	[251,230]	[202,77]	-4	hSpCas9	negative selection	4421294
19219059	19219081	19	-	27760321	OCIAML2	viability	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	0.4925322368580009	[294,265]	[264,389]	6	hSpCas9	negative selection	4504753
19224180	19224202	19	+	27760321	OCIAML2	viability	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.14109232899817403	[675,596]	[390,564]	-2	hSpCas9	negative selection	4504754
19224354	19224376	19	-	27760321	OCIAML2	viability	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	-0.040575597075495184	[628,458]	[308,574]	0	hSpCas9	negative selection	4504755
19225186	19225208	19	-	27760321	OCIAML2	viability	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	-0.21960501484640008	[501,514]	[299,426]	-3	hSpCas9	negative selection	4504756
19225206	19225228	19	-	27760321	OCIAML2	viability	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	0.012559818129952549	[251,230]	[152,254]	0	hSpCas9	negative selection	4504757
19219059	19219081	19	-	27760321	MV411	viability	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	0.2926738876923221	[294,265]	[124,378]	2	hSpCas9	negative selection	4588216
19224180	19224202	19	+	27760321	MV411	viability	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.6943064444028995	[675,596]	[149,422]	-5	hSpCas9	negative selection	4588217
19224354	19224376	19	-	27760321	MV411	viability	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	0.24326414018810644	[628,458]	[258,663]	1	hSpCas9	negative selection	4588218
19225186	19225208	19	-	27760321	MV411	viability	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	-0.39560783573086666	[501,514]	[240,278]	-3	hSpCas9	negative selection	4588219
19225206	19225228	19	-	27760321	MV411	viability	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	-0.615902120623142	[251,230]	[55,175]	-4	hSpCas9	negative selection	4588220
19219059	19219081	19	-	27760321	HL60	viability	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	-0.05722183409863246	[294,265]	[236,201]	0	hSpCas9	negative selection	4671679
19224180	19224202	19	+	27760321	HL60	viability	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.32777063695017855	[675,596]	[463,359]	-4	hSpCas9	negative selection	4671680
19224354	19224376	19	-	27760321	HL60	viability	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	-0.07713699952870012	[628,458]	[374,461]	-1	hSpCas9	negative selection	4671681
19225186	19225208	19	-	27760321	HL60	viability	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	0.006215117526588099	[501,514]	[434,401]	0	hSpCas9	negative selection	4671682
19225206	19225228	19	-	27760321	HL60	viability	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	0.42821466642095835	[251,230]	[343,181]	5	hSpCas9	negative selection	4671683
19219059	19219081	19	-	27760321	HT1080	viability	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	0.5989152670658984	[265,207]	[195,84]	3	hSpCas9	negative selection	4755142
19224180	19224202	19	+	27760321	HT1080	viability	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.6393605566044074	[596,465]	[123,148]	-3	hSpCas9	negative selection	4755143
19224354	19224376	19	-	27760321	HT1080	viability	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	1.7076134348150478	[458,357]	[520,542]	8	hSpCas9	negative selection	4755144
19225186	19225208	19	-	27760321	HT1080	viability	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	-0.032279262344497905	[514,401]	[180,175]	0	hSpCas9	negative selection	4755145
19225206	19225228	19	-	27760321	HT1080	viability	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	0.7038710219314009	[230,179]	[171,90]	4	hSpCas9	negative selection	4755146
19219059	19219081	19	-	27760321	HT29	viability after 7 days	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	-1.24797674503667	[265,207]	[170,64,153]	-9	hSpCas9	negative selection	4838605
19224180	19224202	19	+	27760321	HT29	viability after 7 days	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.5572730104469161	[596,465]	[595,404,411]	-7	hSpCas9	negative selection	4838606
19224354	19224376	19	-	27760321	HT29	viability after 7 days	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	0.12292682682911504	[458,357]	[488,671,542]	1	hSpCas9	negative selection	4838607
19225186	19225208	19	-	27760321	HT29	viability after 7 days	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	-0.05735366330258812	[514,401]	[542,699,455]	-1	hSpCas9	negative selection	4838608
19225206	19225228	19	-	27760321	HT29	viability after 7 days	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	0.37198191351256504	[230,179]	[387,245,395]	5	hSpCas9	negative selection	4838609
19219059	19219081	19	-	27760321	HT29	viability after 25 days	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	-0.4640989973733891	[265,207]	[187,181,221]	-4	hSpCas9	negative selection	4922068
19224180	19224202	19	+	27760321	HT29	viability after 25 days	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.46908367116417793	[596,465]	[302,524,502]	-4	hSpCas9	negative selection	4922069
19224354	19224376	19	-	27760321	HT29	viability after 25 days	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	0.2682357183359028	[458,357]	[401,609,697]	2	hSpCas9	negative selection	4922070
19225186	19225208	19	-	27760321	HT29	viability after 25 days	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	0.01478328413054969	[514,401]	[490,532,569]	0	hSpCas9	negative selection	4922071
19225206	19225228	19	-	27760321	HT29	viability after 25 days	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	0.1160814187652136	[230,179]	[209,205,360]	1	hSpCas9	negative selection	4922072
19219059	19219081	19	-	27760321	HT29	viability after 22 days	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	-0.6309155728630209	[265,207]	[257,161,107]	-5	hSpCas9	negative selection	5005531
19224180	19224202	19	+	27760321	HT29	viability after 22 days	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.51662791699288	[596,465]	[608,310,362]	-5	hSpCas9	negative selection	5005532
19224354	19224376	19	-	27760321	HT29	viability after 22 days	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	0.5548262897331695	[458,357]	[630,732,718]	6	hSpCas9	negative selection	5005533
19225186	19225208	19	-	27760321	HT29	viability after 22 days	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	-0.01638572954713524	[514,401]	[427,703,441]	0	hSpCas9	negative selection	5005534
19225206	19225228	19	-	27760321	HT29	viability after 22 days	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	0.3903075151791358	[230,179]	[199,323,413]	4	hSpCas9	negative selection	5005535
19219059	19219081	19	-	27760321	HT29	viability after 19 days	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	-0.0936743701049545	[265,207]	[183,165,398]	-1	hSpCas9	negative selection	5088994
19224180	19224202	19	+	27760321	HT29	viability after 19 days	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.9057666987931052	[596,465]	[437,248,298]	-6	hSpCas9	negative selection	5088995
19224354	19224376	19	-	27760321	HT29	viability after 19 days	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	0.014476269652152318	[458,357]	[402,529,474]	0	hSpCas9	negative selection	5088996
19225186	19225208	19	-	27760321	HT29	viability after 19 days	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	0.24323082749617508	[514,401]	[748,396,724]	2	hSpCas9	negative selection	5088997
19225206	19225228	19	-	27760321	HT29	viability after 19 days	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	-0.015129528322876729	[230,179]	[229,40,418]	0	hSpCas9	negative selection	5088998
19219059	19219081	19	-	27760321	HT29	viability after 16 days	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	-0.2700930365590355	[265,207]	[301,198,166]	-3	hSpCas9	negative selection	5172457
19224180	19224202	19	+	27760321	HT29	viability after 16 days	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.1543078612968931	[596,465]	[411,585,591]	-2	hSpCas9	negative selection	5172458
19224354	19224376	19	-	27760321	HT29	viability after 16 days	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	0.21889384519887284	[458,357]	[450,682,449]	2	hSpCas9	negative selection	5172459
19225186	19225208	19	-	27760321	HT29	viability after 16 days	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	0.29277674979323076	[514,401]	[697,576,617]	3	hSpCas9	negative selection	5172460
19225206	19225228	19	-	27760321	HT29	viability after 16 days	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	0.5948463468375673	[230,179]	[366,363,311]	7	hSpCas9	negative selection	5172461
19219059	19219081	19	-	27760321	HT29	viability after 13 days	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	-0.4928087971926154	[265,207]	[104,244,233]	-5	hSpCas9	negative selection	5255920
19224180	19224202	19	+	27760321	HT29	viability after 13 days	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.11544345686142848	[596,465]	[524,586,593]	-1	hSpCas9	negative selection	5255921
19224354	19224376	19	-	27760321	HT29	viability after 13 days	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	0.02783971553759987	[458,357]	[278,674,494]	0	hSpCas9	negative selection	5255922
19225186	19225208	19	-	27760321	HT29	viability after 13 days	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	-0.23576131671527886	[514,401]	[362,654,343]	-3	hSpCas9	negative selection	5255923
19225206	19225228	19	-	27760321	HT29	viability after 13 days	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	0.11960385297346932	[230,179]	[274,142,352]	1	hSpCas9	negative selection	5255924
19219059	19219081	19	-	27760321	HT29	viability after 10 days	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	-0.2976635170698305	[265,207]	[234,257,229]	-4	hSpCas9	negative selection	5339383
19224180	19224202	19	+	27760321	HT29	viability after 10 days	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.9231878817782209	[596,465]	[396,332,319]	-7	hSpCas9	negative selection	5339384
19224354	19224376	19	-	27760321	HT29	viability after 10 days	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	0.1713874999917367	[458,357]	[408,488,816]	2	hSpCas9	negative selection	5339385
19225186	19225208	19	-	27760321	HT29	viability after 10 days	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	0.06290259377548119	[514,401]	[633,564,593]	0	hSpCas9	negative selection	5339386
19225206	19225228	19	-	27760321	HT29	viability after 10 days	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	-0.12862849648603547	[230,179]	[257,284,163]	-2	hSpCas9	negative selection	5339387
19219059	19219081	19	-	27760321	MOLM13	viability	TTGGTCCACTTTATCCGAGGGG	NCAN	ENSG00000130287	-2.0196318226255947	[294,265]	[65,15]	-8	hSpCas9	negative selection	5422846
19224180	19224202	19	+	27760321	MOLM13	viability	CTGACCGCACTGTTCGGTGAGG	NCAN	ENSG00000130287	-0.26418710869434264	[675,596]	[170,406]	-2	hSpCas9	negative selection	5422847
19224354	19224376	19	-	27760321	MOLM13	viability	ATAGCTCCGAACCCCTGGAAGG	NCAN	ENSG00000130287	0.7310278313826761	[628,458]	[321,659]	5	hSpCas9	negative selection	5422848
19225186	19225208	19	-	27760321	MOLM13	viability	GGTAGACGGTGCGCACGCCCGG	NCAN	ENSG00000130287	0.9059674481651774	[501,514]	[910,223]	6	hSpCas9	negative selection	5422849
19225206	19225228	19	-	27760321	MOLM13	viability	GCCGGTCCGGTTAGCGAAGCGG	NCAN	ENSG00000130287	-1.5373646165609425	[251,230]	[20,68]	-7	hSpCas9	negative selection	5422850
19212282	19212305	19	+	27661255	K562	viability	GGAATCCGGAGACTACCCCCCGG	NCAN	ENSG00000130287	0.0827158939675191	[946,901]	[819,750]	3	dCas9-KRAB	negative selection	5495753
19212405	19212428	19	+	27661255	K562	viability	GACACCCAGATGCCGAATGGGGG	NCAN	ENSG00000130287	0.3013067878904264	[700,847]	[850,681]	8	dCas9-KRAB	negative selection	5495754
19212444	19212467	19	-	27661255	K562	viability	GTGTCTCGGCTGAGATACGGGGG	NCAN	ENSG00000130287	0.17611430578182385	[879,958]	[901,765]	6	dCas9-KRAB	negative selection	5495755
19212447	19212470	19	-	27661255	K562	viability	GGGGTGTCTCGGCTGAGATACGG	NCAN	ENSG00000130287	0.12246154740843462	[1060,1122]	[960,937]	4	dCas9-KRAB	negative selection	5495756
19218924	19218947	19	+	27260156	BXPC3	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	0.007477665197709482	[611]	[458,688,710,739]	0	hSpCas9	negative selection	5557375
19219075	19219098	19	+	27260156	BXPC3	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.29585904179366374	[236]	[194,215,206,185]	-6	hSpCas9	negative selection	5557376
19224184	19224207	19	-	27260156	BXPC3	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.30526355508861236	[563]	[707,696,743,769]	6	hSpCas9	negative selection	5557377
19224340	19224363	19	+	27260156	BXPC3	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.21211018843850168	[387]	[435,468,396,591]	5	hSpCas9	negative selection	5621634
19224055	19224078	19	+	27260156	BXPC3	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.326785087283739	[381]	[304,295,297,382]	-6	hSpCas9	negative selection	5621635
19224372	19224395	19	+	27260156	BXPC3	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.2228173336438699	[1057]	[1181,1126,1454,1432]	5	hSpCas9	negative selection	5621636
19218924	19218947	19	+	27260156	A673	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.265146022529421	[611]	[616,580,590,659]	-6	hSpCas9	negative selection	5678626
19219075	19219098	19	+	27260156	A673	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.18558926994573277	[236]	[321,369,319,277]	4	hSpCas9	negative selection	5678627
19224184	19224207	19	-	27260156	A673	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.12141038076555183	[563]	[860,693,731,669]	3	hSpCas9	negative selection	5678628
19224340	19224363	19	+	27260156	A673	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.13771389995882027	[387]	[588,550,462,450]	3	hSpCas9	negative selection	5742885
19224055	19224078	19	+	27260156	A673	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.21087413584055403	[381]	[504,458,349,274]	-5	hSpCas9	negative selection	5742886
19224372	19224395	19	+	27260156	A673	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.13935105879783927	[1057]	[1353,1333,1305,1608]	3	hSpCas9	negative selection	5742887
19218924	19218947	19	+	27260156	A375	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.5376229985073819	[611]	[440,719,464,385]	-6	hSpCas9	negative selection	5799877
19219075	19219098	19	+	27260156	A375	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.13662253381561973	[236]	[122,521,285,126]	-2	hSpCas9	negative selection	5799878
19224184	19224207	19	-	27260156	A375	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.2937600718857417	[563]	[814,1187,710,591]	4	hSpCas9	negative selection	5799879
19224340	19224363	19	+	27260156	A375	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.5117906043396464	[387]	[548,775,688,591]	7	hSpCas9	negative selection	5864136
19224055	19224078	19	+	27260156	A375	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.6233294175543714	[381]	[283,306,243,320]	-7	hSpCas9	negative selection	5864137
19224372	19224395	19	+	27260156	A375	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.99646067293955	[1057]	[682,724,441,637]	-8	hSpCas9	negative selection	5864138
19218924	19218947	19	+	27260156	COLO741	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.024337233957435866	[611]	[773,743,785]	0	hSpCas9	negative selection	5921128
19219075	19219098	19	+	27260156	COLO741	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.19001316243528654	[236]	[284,252,481]	4	hSpCas9	negative selection	5921129
19224184	19224207	19	-	27260156	COLO741	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.5720121635404873	[563]	[1780,638,865]	9	hSpCas9	negative selection	5921130
19224340	19224363	19	+	27260156	COLO741	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.3892753393619953	[387]	[691,608,648]	7	hSpCas9	negative selection	5985387
19224055	19224078	19	+	27260156	COLO741	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	0.00016837617314890974	[381]	[664,422,396]	0	hSpCas9	negative selection	5985388
19224372	19224395	19	+	27260156	COLO741	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-1.0314582400617236	[1057]	[756,440,782]	-9	hSpCas9	negative selection	5985389
19218924	19218947	19	+	27260156	CAL120	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	0.11098964589597171	[611]	[1025,722,749]	1	hSpCas9	negative selection	6042379
19219075	19219098	19	+	27260156	CAL120	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	1.122089970098603	[236]	[1351,409,276]	9	hSpCas9	negative selection	6042380
19224184	19224207	19	-	27260156	CAL120	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.7061355942931028	[563]	[1321,818,1316]	9	hSpCas9	negative selection	6042381
19224340	19224363	19	+	27260156	CAL120	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.35028925272205047	[387]	[641,745,464]	5	hSpCas9	negative selection	6106638
19224055	19224078	19	+	27260156	CAL120	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.29531321381182674	[381]	[528,364,290]	-4	hSpCas9	negative selection	6106639
19224372	19224395	19	+	27260156	CAL120	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.7429660889069862	[1057]	[747,604,996]	-8	hSpCas9	negative selection	6106640
19218924	19218947	19	+	27260156	CADOES1	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.24977487466977508	[611]	[468,293,479,678]	-4	hSpCas9	negative selection	6163630
19219075	19219098	19	+	27260156	CADOES1	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.43019078374711905	[236]	[134,216,152,148]	-6	hSpCas9	negative selection	6163631
19224184	19224207	19	-	27260156	CADOES1	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.2609919928611526	[563]	[607,761,557,584]	4	hSpCas9	negative selection	6163632
19224340	19224363	19	+	27260156	CADOES1	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.464993329077338	[387]	[435,462,530,564]	7	hSpCas9	negative selection	6227889
19224055	19224078	19	+	27260156	CADOES1	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.09074368741940358	[381]	[273,402,216,444]	-1	hSpCas9	negative selection	6227890
19224372	19224395	19	+	27260156	CADOES1	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.006226129935035463	[1057]	[956,940,1091,961]	0	hSpCas9	negative selection	6227891
19218924	19218947	19	+	27260156	EWS502	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.21802424494657296	[611]	[559,495,568,607]	-4	hSpCas9	negative selection	6284881
19219075	19219098	19	+	27260156	EWS502	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.37735537094085114	[236]	[303,350,349,297]	6	hSpCas9	negative selection	6284882
19224184	19224207	19	-	27260156	EWS502	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.5241499483933568	[563]	[854,939,790,841]	8	hSpCas9	negative selection	6284883
19224340	19224363	19	+	27260156	EWS502	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.4346640335057188	[387]	[595,617,530,459]	7	hSpCas9	negative selection	6349140
19224055	19224078	19	+	27260156	EWS502	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.11479695156174125	[381]	[369,265,467,396]	-2	hSpCas9	negative selection	6349141
19224372	19224395	19	+	27260156	EWS502	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.019589166081846132	[1057]	[904,1199,994,1487]	0	hSpCas9	negative selection	6349142
19218924	19218947	19	+	27260156	EW8	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.23752952284184142	[611]	[490,283,344,580]	-4	hSpCas9	negative selection	6406132
19219075	19219098	19	+	27260156	EW8	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.32770977704024795	[236]	[125,152,120,213]	-6	hSpCas9	negative selection	6406133
19224184	19224207	19	-	27260156	EW8	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.3460511999036918	[563]	[758,584,486,526]	6	hSpCas9	negative selection	6406134
19224340	19224363	19	+	27260156	EW8	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.5071289786217023	[387]	[700,348,375,399]	8	hSpCas9	negative selection	6470391
19224055	19224078	19	+	27260156	EW8	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	0.019673957561556432	[381]	[519,229,295,233]	0	hSpCas9	negative selection	6470392
19224372	19224395	19	+	27260156	EW8	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.042053040623523774	[1057]	[927,798,851,756]	-1	hSpCas9	negative selection	6470393
19218924	19218947	19	+	27260156	CORL105	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	0.06814782917155243	[611]	[795,673,987,586]	1	hSpCas9	negative selection	6527383
19219075	19219098	19	+	27260156	CORL105	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.06843214359266203	[236]	[194,220,368,287]	-1	hSpCas9	negative selection	6527384
19224184	19224207	19	-	27260156	CORL105	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.5266353399264613	[563]	[1043,799,1024,952]	8	hSpCas9	negative selection	6527385
19224340	19224363	19	+	27260156	CORL105	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.30284392966946977	[387]	[595,479,805,400]	5	hSpCas9	negative selection	6591642
19224055	19224078	19	+	27260156	CORL105	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.2352966886882607	[381]	[419,316,354,425]	-4	hSpCas9	negative selection	6591643
19224372	19224395	19	+	27260156	CORL105	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.16579214853124657	[1057]	[1055,1003,1267,1113]	-3	hSpCas9	negative selection	6591644
19218924	19218947	19	+	27260156	HS294T	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.1458684899321875	[611]	[199,169,291,191]	-2	hSpCas9	negative selection	6648634
19219075	19219098	19	+	27260156	HS294T	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.2195051264437522	[236]	[128,30,68,82]	-3	hSpCas9	negative selection	6648635
19224184	19224207	19	-	27260156	HS294T	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.46854897253580696	[563]	[184,448,252,329]	6	hSpCas9	negative selection	6648636
19224340	19224363	19	+	27260156	HS294T	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.6005956961219177	[387]	[239,150,344,163]	7	hSpCas9	negative selection	6712893
19224055	19224078	19	+	27260156	HS294T	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.3017452603165629	[381]	[71,107,178,125]	-4	hSpCas9	negative selection	6712894
19224372	19224395	19	+	27260156	HS294T	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.17210198062636706	[1057]	[225,283,434,553]	-2	hSpCas9	negative selection	6712895
19218924	19218947	19	+	27260156	HCC44	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.0604665192934577	[611]	[886,505,686,617]	-1	hSpCas9	negative selection	6769885
19219075	19219098	19	+	27260156	HCC44	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.37387049874084965	[236]	[332,246,635,236]	6	hSpCas9	negative selection	6769886
19224184	19224207	19	-	27260156	HCC44	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.5425493847203815	[563]	[1098,614,1050,1021]	8	hSpCas9	negative selection	6769887
19224340	19224363	19	+	27260156	HCC44	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	-0.00466998871112656	[387]	[491,492,377,371]	0	hSpCas9	negative selection	6834144
19224055	19224078	19	+	27260156	HCC44	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.3226979706331301	[381]	[356,303,516,240]	-5	hSpCas9	negative selection	6834145
19224372	19224395	19	+	27260156	HCC44	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-1.109361808091776	[1057]	[611,552,573,485]	-8	hSpCas9	negative selection	6834146
19218924	19218947	19	+	27260156	G402	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.4137485194284517	[611]	[402,425,299,1055]	-5	hSpCas9	negative selection	6891136
19219075	19219098	19	+	27260156	G402	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.25045779951419844	[236]	[548,428,102,328]	3	hSpCas9	negative selection	6891137
19224184	19224207	19	-	27260156	G402	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	-0.04671890793503314	[563]	[668,617,641,727]	0	hSpCas9	negative selection	6891138
19224340	19224363	19	+	27260156	G402	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.40880643538579753	[387]	[811,850,320,569]	5	hSpCas9	negative selection	6955395
19224055	19224078	19	+	27260156	G402	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.9124736158601408	[381]	[355,188,212,243]	-8	hSpCas9	negative selection	6955396
19224372	19224395	19	+	27260156	G402	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.3928385603264357	[1057]	[2030,1410,1509,1845]	5	hSpCas9	negative selection	6955397
19218924	19218947	19	+	27260156	L33	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	0.0322570767588542	[611]	[761,216,391,584]	0	hSpCas9	negative selection	7012387
19219075	19219098	19	+	27260156	L33	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.19615038840359666	[236]	[191,78,157,191]	-4	hSpCas9	negative selection	7012388
19224184	19224207	19	-	27260156	L33	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.5440541901114548	[563]	[778,295,546,917]	9	hSpCas9	negative selection	7012389
19224340	19224363	19	+	27260156	L33	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.011376730951830671	[387]	[388,153,280,352]	0	hSpCas9	negative selection	7076646
19224055	19224078	19	+	27260156	L33	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	0.10271231503265266	[381]	[421,142,242,481]	2	hSpCas9	negative selection	7076647
19224372	19224395	19	+	27260156	L33	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.5585598941273785	[1057]	[614,325,384,850]	-8	hSpCas9	negative selection	7076648
19218924	19218947	19	+	27260156	K562	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.2503207405221825	[611]	[600,290,652,300]	-3	hSpCas9	negative selection	7133638
19219075	19219098	19	+	27260156	K562	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.48585745530161273	[236]	[324,400,126,327]	6	hSpCas9	negative selection	7133639
19224184	19224207	19	-	27260156	K562	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.3007395171942422	[563]	[656,895,656,307]	4	hSpCas9	negative selection	7133640
19224340	19224363	19	+	27260156	K562	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.7337443585220578	[387]	[520,416,561,753]	8	hSpCas9	negative selection	7197897
19224055	19224078	19	+	27260156	K562	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.4528623560461297	[381]	[156,317,235,271]	-5	hSpCas9	negative selection	7197898
19224372	19224395	19	+	27260156	K562	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.009917566855926818	[1057]	[886,1171,858,828]	0	hSpCas9	negative selection	7197899
19218924	19218947	19	+	27260156	HT29	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.32410579578445664	[611]	[701,694,589,423]	-6	hSpCas9	negative selection	7254889
19219075	19219098	19	+	27260156	HT29	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.17137597283055306	[236]	[283,248,206,279]	-3	hSpCas9	negative selection	7254890
19224184	19224207	19	-	27260156	HT29	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.04326924137519894	[563]	[787,647,831,570]	0	hSpCas9	negative selection	7254891
19224340	19224363	19	+	27260156	HT29	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.4810307902449807	[387]	[726,817,574,541]	8	hSpCas9	negative selection	7319148
19224055	19224078	19	+	27260156	HT29	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.15638002964550612	[381]	[583,368,424,307]	-3	hSpCas9	negative selection	7319149
19224372	19224395	19	+	27260156	HT29	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.053310172918223264	[1057]	[1285,1580,1263,893]	-1	hSpCas9	negative selection	7319150
19218924	19218947	19	+	27260156	MHHES1	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.6350097637137112	[611]	[391,535,386,450]	-8	hSpCas9	negative selection	7376140
19219075	19219098	19	+	27260156	MHHES1	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.5444419366391693	[236]	[177,298,167,110]	-7	hSpCas9	negative selection	7376141
19224184	19224207	19	-	27260156	MHHES1	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.15582604157646307	[563]	[678,637,940,577]	3	hSpCas9	negative selection	7376142
19224340	19224363	19	+	27260156	MHHES1	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.20849760842920673	[387]	[729,362,481,456]	4	hSpCas9	negative selection	7440399
19224055	19224078	19	+	27260156	MHHES1	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.599871132197689	[381]	[233,232,431,231]	-8	hSpCas9	negative selection	7440400
19224372	19224395	19	+	27260156	MHHES1	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.09273928887208793	[1057]	[2201,1187,1107,775]	1	hSpCas9	negative selection	7440401
19218924	19218947	19	+	27260156	MEWO	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.1635791995591371	[611]	[590,493,463]	-4	hSpCas9	negative selection	7497391
19219075	19219098	19	+	27260156	MEWO	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.16686970297141224	[236]	[285,223,243]	3	hSpCas9	negative selection	7497392
19224184	19224207	19	-	27260156	MEWO	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.3244388023812952	[563]	[725,590,677]	7	hSpCas9	negative selection	7497393
19224340	19224363	19	+	27260156	MEWO	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.20011936014062787	[387]	[499,419,346]	4	hSpCas9	negative selection	7561650
19224055	19224078	19	+	27260156	MEWO	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.057984924886081146	[381]	[389,319,328]	-1	hSpCas9	negative selection	7561651
19224372	19224395	19	+	27260156	MEWO	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.9959120726908235	[1057]	[614,461,434]	-9	hSpCas9	negative selection	7561652
19218924	19218947	19	+	27260156	LNCAPCLONEFGC	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.3841977796916632	[611]	[401,379,537,398]	-5	hSpCas9	negative selection	7618642
19219075	19219098	19	+	27260156	LNCAPCLONEFGC	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.13866804287397905	[236]	[318,166,207,249]	2	hSpCas9	negative selection	7618643
19224184	19224207	19	-	27260156	LNCAPCLONEFGC	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.4225840954403367	[563]	[849,624,688,575]	6	hSpCas9	negative selection	7618644
19224340	19224363	19	+	27260156	LNCAPCLONEFGC	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.5224185940696386	[387]	[470,458,708,413]	7	hSpCas9	negative selection	7682901
19224055	19224078	19	+	27260156	LNCAPCLONEFGC	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.280120431304571	[381]	[371,349,185,210]	-4	hSpCas9	negative selection	7682902
19224372	19224395	19	+	27260156	LNCAPCLONEFGC	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-1.350648886245025	[1057]	[286,436,411,369]	-9	hSpCas9	negative selection	7682903
19218924	19218947	19	+	27260156	PANC0327	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.11521162163830284	[611]	[433,389,808,383]	-2	hSpCas9	negative selection	7739893
19219075	19219098	19	+	27260156	PANC0327	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.4767495478927546	[236]	[82,216,142,147]	-6	hSpCas9	negative selection	7739894
19224184	19224207	19	-	27260156	PANC0327	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.5853542165412254	[563]	[764,598,615,1046]	8	hSpCas9	negative selection	7739895
19224340	19224363	19	+	27260156	PANC0327	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.06239765417062185	[387]	[405,235,278,537]	0	hSpCas9	negative selection	7804152
19224055	19224078	19	+	27260156	PANC0327	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.8207389797001623	[381]	[189,171,273,134]	-8	hSpCas9	negative selection	7804153
19224372	19224395	19	+	27260156	PANC0327	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.06673139607363443	[1057]	[1198,743,1165,876]	1	hSpCas9	negative selection	7804154
19218924	19218947	19	+	27260156	NCIH2009	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.0665490469920163	[611]	[766,1001,665]	-1	hSpCas9	negative selection	7861144
19219075	19219098	19	+	27260156	NCIH2009	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.028997696187658573	[236]	[375,255,389]	0	hSpCas9	negative selection	7861145
19224184	19224207	19	-	27260156	NCIH2009	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.4307114192352993	[563]	[1182,1199,822]	6	hSpCas9	negative selection	7861146
19224340	19224363	19	+	27260156	NCIH2009	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.5940999446728421	[387]	[1086,633,788]	7	hSpCas9	negative selection	7925403
19224055	19224078	19	+	27260156	NCIH2009	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	0.1068342487085494	[381]	[786,474,504]	1	hSpCas9	negative selection	7925404
19224372	19224395	19	+	27260156	NCIH2009	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.14054998438869037	[1057]	[1273,1528,1200]	-2	hSpCas9	negative selection	7925405
19218924	19218947	19	+	27260156	NCIH1373	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	0.3864875547850359	[611]	[939,1233,498,232]	4	hSpCas9	negative selection	7982395
19219075	19219098	19	+	27260156	NCIH1373	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.45753824485300343	[236]	[222,191,154,54]	-4	hSpCas9	negative selection	7982396
19224184	19224207	19	-	27260156	NCIH1373	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.2850012516042125	[563]	[1096,651,807,149]	3	hSpCas9	negative selection	7982397
19224340	19224363	19	+	27260156	NCIH1373	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.842570666392744	[387]	[1184,473,751,210]	8	hSpCas9	negative selection	8046654
19224055	19224078	19	+	27260156	NCIH1373	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.1681974933806939	[381]	[255,332,156,207]	-2	hSpCas9	negative selection	8046655
19224372	19224395	19	+	27260156	NCIH1373	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.21166279050309944	[1057]	[1133,1302,1670,351]	2	hSpCas9	negative selection	8046656
19218924	19218947	19	+	27260156	PATU8902	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.552319730277909	[611]	[1049,211,438,657]	-5	hSpCas9	negative selection	8103646
19219075	19219098	19	+	27260156	PATU8902	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-1.8597121245157604	[236]	[187,19,15,165]	-9	hSpCas9	negative selection	8103647
19224184	19224207	19	-	27260156	PATU8902	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.3359693415554982	[563]	[475,675,1288,1506]	3	hSpCas9	negative selection	8103648
19224340	19224363	19	+	27260156	PATU8902	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.4293241246662709	[387]	[1088,947,500,379]	4	hSpCas9	negative selection	8167905
19224055	19224078	19	+	27260156	PATU8902	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-1.1723255794014	[381]	[395,145,128,304]	-8	hSpCas9	negative selection	8167906
19224372	19224395	19	+	27260156	PATU8902	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.21906219920987358	[1057]	[1286,1899,1549,2218]	2	hSpCas9	negative selection	8167907
19218924	19218947	19	+	27260156	PANC1	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	0.04245259629293929	[611]	[410,885,583,376]	0	hSpCas9	negative selection	8224897
19219075	19219098	19	+	27260156	PANC1	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.6185655695403536	[236]	[100,128,189,111]	-7	hSpCas9	negative selection	8224898
19224184	19224207	19	-	27260156	PANC1	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.12827455359976586	[563]	[463,585,541,529]	2	hSpCas9	negative selection	8224899
19224340	19224363	19	+	27260156	PANC1	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	-0.06971284411859296	[387]	[314,340,272,336]	-1	hSpCas9	negative selection	8289156
19224055	19224078	19	+	27260156	PANC1	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.502740440808332	[381]	[210,154,278,257]	-6	hSpCas9	negative selection	8289157
19224372	19224395	19	+	27260156	PANC1	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.02950814269683022	[1057]	[879,1068,874,777]	0	hSpCas9	negative selection	8289158
19218924	19218947	19	+	27260156	PANC0813	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.060762482766454184	[611]	[651,721,717,661]	-1	hSpCas9	negative selection	8346148
19219075	19219098	19	+	27260156	PANC0813	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-1.098844963848463	[236]	[148,173,65,131]	-8	hSpCas9	negative selection	8346149
19224184	19224207	19	-	27260156	PANC0813	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.603970459808002	[563]	[1275,953,1018,812]	8	hSpCas9	negative selection	8346150
19224340	19224363	19	+	27260156	PANC0813	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	-0.019060637427884553	[387]	[505,521,480,302]	0	hSpCas9	negative selection	8410407
19224055	19224078	19	+	27260156	PANC0813	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.03569626082788446	[381]	[380,485,508,372]	0	hSpCas9	negative selection	8410408
19224372	19224395	19	+	27260156	PANC0813	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.2003672655019435	[1057]	[1096,1068,1299,872]	-3	hSpCas9	negative selection	8410409
19218924	19218947	19	+	27260156	RDES	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.1825197652037024	[611]	[504,550,673,791]	-3	hSpCas9	negative selection	8467399
19219075	19219098	19	+	27260156	RDES	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.413023569559519	[236]	[314,336,403,404]	6	hSpCas9	negative selection	8467400
19224184	19224207	19	-	27260156	RDES	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.2799000296005121	[563]	[593,765,790,1061]	4	hSpCas9	negative selection	8467401
19224340	19224363	19	+	27260156	RDES	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.44300989050896056	[387]	[414,603,604,866]	7	hSpCas9	negative selection	8531658
19224055	19224078	19	+	27260156	RDES	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.3255493939221652	[381]	[288,271,365,510]	-5	hSpCas9	negative selection	8531659
19224372	19224395	19	+	27260156	RDES	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.9774616825606188	[1057]	[508,555,803,620]	-9	hSpCas9	negative selection	8531660
19218924	19218947	19	+	27260156	PC3	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.37193728142958393	[611]	[293,569,668,453]	-7	hSpCas9	negative selection	8588650
19219075	19219098	19	+	27260156	PC3	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.33369842132425787	[236]	[166,292,744,186]	7	hSpCas9	negative selection	8588651
19224184	19224207	19	-	27260156	PC3	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.15135452707532643	[563]	[371,626,1081,647]	3	hSpCas9	negative selection	8588652
19224340	19224363	19	+	27260156	PC3	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.4462917089688624	[387]	[440,370,1015,447]	8	hSpCas9	negative selection	8652909
19224055	19224078	19	+	27260156	PC3	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.21039769389242668	[381]	[159,525,488,234]	-5	hSpCas9	negative selection	8652910
19224372	19224395	19	+	27260156	PC3	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-1.4323288928217608	[1057]	[224,291,815,441]	-9	hSpCas9	negative selection	8652911
19218924	19218947	19	+	27260156	PATU8988T	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.45571426153594674	[611]	[440,378,441,459]	-6	hSpCas9	negative selection	8709901
19219075	19219098	19	+	27260156	PATU8988T	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.03677022851910028	[236]	[225,301,277,130]	0	hSpCas9	negative selection	8709902
19224184	19224207	19	-	27260156	PATU8988T	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.2700761639565853	[563]	[934,649,415,627]	4	hSpCas9	negative selection	8709903
19224340	19224363	19	+	27260156	PATU8988T	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.12934297831013714	[387]	[339,381,448,470]	2	hSpCas9	negative selection	8774160
19224055	19224078	19	+	27260156	PATU8988T	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	0.20406915290225106	[381]	[759,296,314,308]	3	hSpCas9	negative selection	8774161
19224372	19224395	19	+	27260156	PATU8988T	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.190896193871247	[1057]	[960,1151,1346,1206]	3	hSpCas9	negative selection	8774162
19218924	19218947	19	+	27260156	T47D	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.10172626206974883	[611]	[696,666,587,707]	-2	hSpCas9	negative selection	8831152
19219075	19219098	19	+	27260156	T47D	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.05913032482538361	[236]	[261,258,280,257]	-1	hSpCas9	negative selection	8831153
19224184	19224207	19	-	27260156	T47D	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.23867421077207351	[563]	[916,685,768,735]	5	hSpCas9	negative selection	8831154
19224340	19224363	19	+	27260156	T47D	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.16260258805612118	[387]	[449,454,433,695]	3	hSpCas9	negative selection	8895411
19224055	19224078	19	+	27260156	T47D	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.5472790671077665	[381]	[351,312,296,253]	-8	hSpCas9	negative selection	8895412
19224372	19224395	19	+	27260156	T47D	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.03483758082213706	[1057]	[1189,1188,1331,1346]	0	hSpCas9	negative selection	8895413
19218924	19218947	19	+	27260156	SU8686	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.2702746048164707	[611]	[285,639,451,661]	-4	hSpCas9	negative selection	8952403
19219075	19219098	19	+	27260156	SU8686	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.5866414074054136	[236]	[204,118,171,122]	-7	hSpCas9	negative selection	8952404
19224184	19224207	19	-	27260156	SU8686	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.4332386309246038	[563]	[703,605,837,920]	7	hSpCas9	negative selection	8952405
19224340	19224363	19	+	27260156	SU8686	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.1501108860311961	[387]	[400,476,473,334]	2	hSpCas9	negative selection	9016662
19224055	19224078	19	+	27260156	SU8686	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.3908160377082177	[381]	[199,334,338,283]	-6	hSpCas9	negative selection	9016663
19224372	19224395	19	+	27260156	SU8686	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-0.30610608953465723	[1057]	[897,815,884,775]	-5	hSpCas9	negative selection	9016664
19218924	19218947	19	+	27260156	SKES1	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.08251454880780873	[611]	[564,507,604,607]	-2	hSpCas9	negative selection	9073654
19219075	19219098	19	+	27260156	SKES1	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.18902437769626756	[236]	[275,331,295,188]	4	hSpCas9	negative selection	9073655
19224184	19224207	19	-	27260156	SKES1	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.15055981426215648	[563]	[593,677,608,613]	3	hSpCas9	negative selection	9073656
19224340	19224363	19	+	27260156	SKES1	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.2679055790064173	[387]	[552,444,462,413]	5	hSpCas9	negative selection	9137913
19224055	19224078	19	+	27260156	SKES1	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.053728894317012166	[381]	[365,348,295,442]	-1	hSpCas9	negative selection	9137914
19224372	19224395	19	+	27260156	SKES1	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-1.0483291091812177	[1057]	[458,755,536,327]	-9	hSpCas9	negative selection	9137915
19218924	19218947	19	+	27260156	TOV112D	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	0.031017734932114793	[611]	[743,472,696,563]	0	hSpCas9	negative selection	9194905
19219075	19219098	19	+	27260156	TOV112D	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.09253285820192403	[236]	[201,237,385,179]	1	hSpCas9	negative selection	9194906
19224184	19224207	19	-	27260156	TOV112D	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.40871460630202383	[563]	[743,664,532,1026]	7	hSpCas9	negative selection	9194907
19224340	19224363	19	+	27260156	TOV112D	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.28556381482273385	[387]	[691,636,314,312]	5	hSpCas9	negative selection	9259164
19224055	19224078	19	+	27260156	TOV112D	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.47534616258657514	[381]	[345,394,163,231]	-7	hSpCas9	negative selection	9259165
19224372	19224395	19	+	27260156	TOV112D	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	-1.419558356067845	[1057]	[542,329,385,322]	-9	hSpCas9	negative selection	9259166
19218924	19218947	19	+	27260156	TC71	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.19881685178065794	[611]	[521,753,508,499]	-5	hSpCas9	negative selection	9316156
19219075	19219098	19	+	27260156	TC71	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	0.13026717067398952	[236]	[260,385,194,272]	3	hSpCas9	negative selection	9316157
19224184	19224207	19	-	27260156	TC71	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.09611604751989383	[563]	[655,575,631,725]	2	hSpCas9	negative selection	9316158
19224340	19224363	19	+	27260156	TC71	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.05856867666836238	[387]	[362,480,409,483]	1	hSpCas9	negative selection	9380415
19224055	19224078	19	+	27260156	TC71	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.04309127496687215	[381]	[345,426,380,439]	-1	hSpCas9	negative selection	9380416
19224372	19224395	19	+	27260156	TC71	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.054526273896725375	[1057]	[1314,1276,971,1148]	1	hSpCas9	negative selection	9380417
19218924	19218947	19	+	27260156	TC32	viability	ATATCACCGATGCCAGCGAAAGG	NCAN	ENSG00000130287	-0.4605452457386566	[611]	[421,186,602,564]	-7	hSpCas9	negative selection	9437407
19219075	19219098	19	+	27260156	TC32	viability	GACCAAGGTGCGGACTGCGTCGG	NCAN	ENSG00000130287	-0.013702440369761426	[236]	[227,143,303,236]	0	hSpCas9	negative selection	9437408
19224184	19224207	19	-	27260156	TC32	viability	ATCCCCCTCACCGAACAGTGCGG	NCAN	ENSG00000130287	0.43332431638223234	[563]	[603,553,914,865]	7	hSpCas9	negative selection	9437409
19224340	19224363	19	+	27260156	TC32	viability	GGCGACCGTAGCAGCCTTCCAGG	NCAN	ENSG00000130287	0.6461586078075249	[387]	[477,447,841,586]	9	hSpCas9	negative selection	9501666
19224055	19224078	19	+	27260156	TC32	viability	CTATGCACTGACCTTCGCTGAGG	NCAN	ENSG00000130287	-0.018817160273624567	[381]	[322,270,511,352]	0	hSpCas9	negative selection	9501667
19224372	19224395	19	+	27260156	TC32	viability	CTATGGGAGGCGCAACCCACAGG	NCAN	ENSG00000130287	0.10054294472606307	[1057]	[1095,727,1435,1132]	1	hSpCas9	negative selection	9501668
19216963	19216986	19	-	27869803	HPAFII	viability after 27 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	1.2751713012809112	[309]	[454,343,NaN]	9	hSpCas9	negative selection	9566619
19219060	19219083	19	-	27869803	HPAFII	viability after 27 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	0.26228813829184633	[187]	[237,18,NaN]	2	hSpCas9	negative selection	9566620
19224027	19224050	19	+	27869803	HPAFII	viability after 27 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.18425818598088445	[233]	[38,165,NaN]	-1	hSpCas9	negative selection	9566621
19224324	19224347	19	-	27869803	HPAFII	viability after 27 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.6663233139848921	[117]	[98,97,NaN]	5	hSpCas9	negative selection	9566622
19225237	19225260	19	-	27869803	HPAFII	viability after 27 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	-0.6467151212935969	[48]	[28,5,NaN]	-5	hSpCas9	negative selection	9566623
19226796	19226819	19	+	27869803	HPAFII	viability after 27 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	0.12741515526047587	[554]	[441,215,NaN]	1	hSpCas9	negative selection	9566624
19216963	19216986	19	-	27869803	HPAFII	viability after 15 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.48679247375803397	[309]	[723,306,NaN]	5	hSpCas9	negative selection	9649068
19219060	19219083	19	-	27869803	HPAFII	viability after 15 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.3946096813343001	[187]	[305,58,NaN]	-4	hSpCas9	negative selection	9649069
19224027	19224050	19	+	27869803	HPAFII	viability after 15 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.30110173044061267	[233]	[184,215,NaN]	-3	hSpCas9	negative selection	9649070
19224324	19224347	19	-	27869803	HPAFII	viability after 15 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.36273619013627767	[117]	[204,136,NaN]	4	hSpCas9	negative selection	9649071
19225237	19225260	19	-	27869803	HPAFII	viability after 15 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	0.46234956918670655	[48]	[140,29,NaN]	5	hSpCas9	negative selection	9649072
19226796	19226819	19	+	27869803	HPAFII	viability after 15 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	0.05997708343752284	[554]	[569,653,NaN]	0	hSpCas9	negative selection	9649073
19216963	19216986	19	-	27869803	ASPC1	viability after 36 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.16739578372919123	[863]	[242,362,382]	1	hSpCas9	negative selection	9731517
19219060	19219083	19	-	27869803	ASPC1	viability after 36 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	0.12222758238505932	[495]	[326,53,195]	1	hSpCas9	negative selection	9731518
19224027	19224050	19	+	27869803	ASPC1	viability after 36 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.42205961685384014	[488]	[86,171,118]	-4	hSpCas9	negative selection	9731519
19224324	19224347	19	-	27869803	ASPC1	viability after 36 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.973865083582206	[286]	[20,386,166]	8	hSpCas9	negative selection	9731520
19225237	19225260	19	-	27869803	ASPC1	viability after 36 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	1.0300433767835064	[109]	[0,8,186]	8	hSpCas9	negative selection	9731521
19226796	19226819	19	+	27869803	ASPC1	viability after 36 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	0.39704278770165957	[1401]	[1603,537,48]	4	hSpCas9	negative selection	9731522
19216963	19216986	19	-	27869803	PATU8988S	viability after 35 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.5037066676800817	[618]	[341,364,NaN]	5	hSpCas9	negative selection	9813966
19219060	19219083	19	-	27869803	PATU8988S	viability after 35 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.9288976707432557	[498]	[132,77,NaN]	-7	hSpCas9	negative selection	9813967
19224027	19224050	19	+	27869803	PATU8988S	viability after 35 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	0.22196243326364484	[406]	[270,110,NaN]	2	hSpCas9	negative selection	9813968
19224324	19224347	19	-	27869803	PATU8988S	viability after 35 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.5705343408871246	[305]	[192,172,NaN]	6	hSpCas9	negative selection	9813969
19225237	19225260	19	-	27869803	PATU8988S	viability after 35 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	1.3536681417473277	[66]	[51,85,NaN]	9	hSpCas9	negative selection	9813970
19226796	19226819	19	+	27869803	PATU8988S	viability after 35 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.41345796851025673	[1303]	[315,472,NaN]	-4	hSpCas9	negative selection	9813971
19216963	19216986	19	-	27869803	PATU8988S	viability after 31 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	0.18625944092364832	[618]	[264,300,NaN]	2	hSpCas9	negative selection	9896415
19219060	19219083	19	-	27869803	PATU8988S	viability after 31 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.5223914237752041	[498]	[178,86,NaN]	-5	hSpCas9	negative selection	9896416
19224027	19224050	19	+	27869803	PATU8988S	viability after 31 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	0.3591224632078682	[406]	[201,215,NaN]	4	hSpCas9	negative selection	9896417
19224324	19224347	19	-	27869803	PATU8988S	viability after 31 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.7233175570591976	[305]	[222,173,NaN]	8	hSpCas9	negative selection	9896418
19225237	19225260	19	-	27869803	PATU8988S	viability after 31 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	1.2513019986315055	[66]	[56,71,NaN]	9	hSpCas9	negative selection	9896419
19226796	19226819	19	+	27869803	PATU8988S	viability after 31 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.38727297887453194	[1303]	[342,466,NaN]	-4	hSpCas9	negative selection	9896420
19216963	19216986	19	-	27869803	HPAFII	viability after 35 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	1.428170951091243	[309]	[482,353,NaN]	8	hSpCas9	negative selection	9978864
19219060	19219083	19	-	27869803	HPAFII	viability after 35 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.4209873343525301	[187]	[127,6,NaN]	-3	hSpCas9	negative selection	9978865
19224027	19224050	19	+	27869803	HPAFII	viability after 35 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.6107176889723945	[233]	[54,102,NaN]	-4	hSpCas9	negative selection	9978866
19224324	19224347	19	-	27869803	HPAFII	viability after 35 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.7972509635135043	[117]	[76,133,NaN]	5	hSpCas9	negative selection	9978867
19225237	19225260	19	-	27869803	HPAFII	viability after 35 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	0.402063511183534	[48]	[60,0,NaN]	2	hSpCas9	negative selection	9978868
19226796	19226819	19	+	27869803	HPAFII	viability after 35 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.0736662661223304	[554]	[226,311,NaN]	0	hSpCas9	negative selection	9978869
19216963	19216986	19	-	27869803	HPAFII	viability after 31 days	AGGCCCAAGGCCCAGACAAACGG	NCAN	ENSG00000130287	1.3153748100092384	[309]	[543,311,NaN]	8	hSpCas9	negative selection	10061313
19219060	19219083	19	-	27869803	HPAFII	viability after 31 days	CCTTGGTCCACTTTATCCGAGGG	NCAN	ENSG00000130287	-0.06883359575652609	[187]	[191,0,NaN]	0	hSpCas9	negative selection	10061314
19224027	19224050	19	+	27869803	HPAFII	viability after 31 days	TGTTCCACTACCGATCAGCCCGG	NCAN	ENSG00000130287	-0.25535278926591093	[233]	[76,145,NaN]	-2	hSpCas9	negative selection	10061315
19224324	19224347	19	-	27869803	HPAFII	viability after 31 days	GGTCGCCATAGCAACCAGGACGG	NCAN	ENSG00000130287	0.664482871907145	[117]	[92,117,NaN]	5	hSpCas9	negative selection	10061316
19225237	19225260	19	-	27869803	HPAFII	viability after 31 days	TAGGCGTCGAAGCGCTCGGCGGG	NCAN	ENSG00000130287	0.581481881094313	[48]	[77,0,NaN]	4	hSpCas9	negative selection	10061317
19226796	19226819	19	+	27869803	HPAFII	viability after 31 days	CACTGCAGCAAGTTCACACACGG	NCAN	ENSG00000130287	-0.017525149075607205	[554]	[345,265,NaN]	0	hSpCas9	negative selection	10061318
19227644	19227667	19	-	28162770	P31FUJ	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	-0.13794301807293724	[308]	[329]	-1	hSpCas9	negative selection	10198109
19226745	19226768	19	+	28162770	P31FUJ	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	1.1872359759228315	[107]	[288]	9	hSpCas9	negative selection	10198110
19238371	19238394	19	+	28162770	P31FUJ	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-1.286440168016452	[273]	[131]	-7	hSpCas9	negative selection	10198111
19219009	19219032	19	-	28162770	P31FUJ	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-1.4551946257508266	[230]	[98]	-7	hSpCas9	negative selection	10198112
19219065	19219088	19	+	28162770	P31FUJ	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-0.9128119137685089	[148]	[92]	-6	hSpCas9	negative selection	10198113
19224066	19224089	19	-	28162770	P31FUJ	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-3.49958874510928	[76]	[7]	-9	hSpCas9	negative selection	10198114
19224119	19224142	19	-	28162770	P31FUJ	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	0.05670441278060623	[71]	[87]	0	hSpCas9	negative selection	10198115
19224342	19224365	19	+	28162770	P31FUJ	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	-0.5148101113644906	[596]	[490]	-4	hSpCas9	negative selection	10198116
19225061	19225084	19	-	28162770	P31FUJ	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	0.10981828562608498	[622]	[789]	1	hSpCas9	negative selection	10198117
19226580	19226603	19	+	28162770	P31FUJ	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-2.2513381558518066	[234]	[57]	-8	hSpCas9	negative selection	10198118
19227644	19227667	19	-	28162770	TF1	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	NaN	[NaN]	[169]	1	hSpCas9	negative selection	10367475
19226745	19226768	19	+	28162770	TF1	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10367476
19238371	19238394	19	+	28162770	TF1	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10367477
19219009	19219032	19	-	28162770	TF1	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10367478
19219065	19219088	19	+	28162770	TF1	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10367479
19224066	19224089	19	-	28162770	TF1	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10367480
19224119	19224142	19	-	28162770	TF1	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10367481
19224342	19224365	19	+	28162770	TF1	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	NaN	[NaN]	[244]	1	hSpCas9	negative selection	10367482
19225061	19225084	19	-	28162770	TF1	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	NaN	[NaN]	[396]	1	hSpCas9	negative selection	10367483
19226580	19226603	19	+	28162770	TF1	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10367484
19227644	19227667	19	-	28162770	SKM1	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	0.233851536711512	[75]	[157]	2	hSpCas9	negative selection	10536841
19226745	19226768	19	+	28162770	SKM1	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	-0.5849625007211563	[27]	[32]	-5	hSpCas9	negative selection	10536842
19238371	19238394	19	+	28162770	SKM1	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-1.737609510731633	[82]	[43]	-8	hSpCas9	negative selection	10536843
19219009	19219032	19	-	28162770	SKM1	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-1.0223003485078368	[53]	[46]	-6	hSpCas9	negative selection	10536844
19219065	19219088	19	+	28162770	SKM1	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-0.6520766965796932	[47]	[53]	-5	hSpCas9	negative selection	10536845
19224066	19224089	19	-	28162770	SKM1	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-2.3580545982622154	[28]	[9]	-8	hSpCas9	negative selection	10536846
19224119	19224142	19	-	28162770	SKM1	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	0.6849582906978773	[18]	[53]	6	hSpCas9	negative selection	10536847
19224342	19224365	19	+	28162770	SKM1	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	0.29867978440045784	[148]	[323]	3	hSpCas9	negative selection	10536848
19225061	19225084	19	-	28162770	SKM1	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	-0.18973348252249256	[139]	[216]	-2	hSpCas9	negative selection	10536849
19226580	19226603	19	+	28162770	SKM1	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-3.3525164147207853	[51]	[8]	-9	hSpCas9	negative selection	10536850
19227644	19227667	19	-	28162770	SKM1	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	0.233851536711512	[75]	[157]	2	hSpCas9	negative selection	10706207
19226745	19226768	19	+	28162770	SKM1	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	-0.5849625007211563	[27]	[32]	-5	hSpCas9	negative selection	10706208
19238371	19238394	19	+	28162770	SKM1	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-1.737609510731633	[82]	[43]	-8	hSpCas9	negative selection	10706209
19219009	19219032	19	-	28162770	SKM1	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-1.0223003485078368	[53]	[46]	-6	hSpCas9	negative selection	10706210
19219065	19219088	19	+	28162770	SKM1	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-0.6520766965796932	[47]	[53]	-5	hSpCas9	negative selection	10706211
19224066	19224089	19	-	28162770	SKM1	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-2.3580545982622154	[28]	[9]	-8	hSpCas9	negative selection	10706212
19224119	19224142	19	-	28162770	SKM1	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	0.6849582906978773	[18]	[53]	6	hSpCas9	negative selection	10706213
19224342	19224365	19	+	28162770	SKM1	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	0.29867978440045784	[148]	[323]	3	hSpCas9	negative selection	10706214
19225061	19225084	19	-	28162770	SKM1	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	-0.18973348252249256	[139]	[216]	-2	hSpCas9	negative selection	10706215
19226580	19226603	19	+	28162770	SKM1	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-3.3525164147207853	[51]	[8]	-9	hSpCas9	negative selection	10706216
19227644	19227667	19	-	28162770	PL21	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	-0.16701773439103973	[404]	[156]	-1	hSpCas9	negative selection	10875573
19226745	19226768	19	+	28162770	PL21	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	-0.7796825035730497	[70]	[17]	-5	hSpCas9	negative selection	10875574
19238371	19238394	19	+	28162770	PL21	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-1.0767005908695042	[251]	[51]	-6	hSpCas9	negative selection	10875575
19219009	19219032	19	-	28162770	PL21	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-0.10861309165030891	[217]	[87]	-1	hSpCas9	negative selection	10875576
19219065	19219088	19	+	28162770	PL21	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-0.6026280380726321	[156]	[44]	-4	hSpCas9	negative selection	10875577
19224066	19224089	19	-	28162770	PL21	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-0.7998603855106801	[71]	[17]	-5	hSpCas9	negative selection	10875578
19224119	19224142	19	-	28162770	PL21	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	-0.07996830470341498	[84]	[34]	0	hSpCas9	negative selection	10875579
19224342	19224365	19	+	28162770	PL21	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	-0.6873856562522672	[480]	[129]	-5	hSpCas9	negative selection	10875580
19225061	19225084	19	-	28162770	PL21	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	0.8830125058657791	[374]	[300]	7	hSpCas9	negative selection	10875581
19226580	19226603	19	+	28162770	PL21	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-0.9888942099006969	[113]	[24]	-6	hSpCas9	negative selection	10875582
19227644	19227667	19	-	28162770	P31FUJ	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	-0.13794301807293724	[308]	[329]	-1	hSpCas9	negative selection	11044939
19226745	19226768	19	+	28162770	P31FUJ	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	1.1872359759228315	[107]	[288]	9	hSpCas9	negative selection	11044940
19238371	19238394	19	+	28162770	P31FUJ	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-1.286440168016452	[273]	[131]	-7	hSpCas9	negative selection	11044941
19219009	19219032	19	-	28162770	P31FUJ	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-1.4551946257508266	[230]	[98]	-7	hSpCas9	negative selection	11044942
19219065	19219088	19	+	28162770	P31FUJ	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-0.9128119137685089	[148]	[92]	-6	hSpCas9	negative selection	11044943
19224066	19224089	19	-	28162770	P31FUJ	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-3.49958874510928	[76]	[7]	-9	hSpCas9	negative selection	11044944
19224119	19224142	19	-	28162770	P31FUJ	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	0.05670441278060623	[71]	[87]	0	hSpCas9	negative selection	11044945
19224342	19224365	19	+	28162770	P31FUJ	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	-0.5148101113644906	[596]	[490]	-4	hSpCas9	negative selection	11044946
19225061	19225084	19	-	28162770	P31FUJ	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	0.10981828562608498	[622]	[789]	1	hSpCas9	negative selection	11044947
19226580	19226603	19	+	28162770	P31FUJ	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-2.2513381558518066	[234]	[57]	-8	hSpCas9	negative selection	11044948
19227644	19227667	19	-	28162770	OCIAML5	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	-0.0017595036218457372	[207]	[374]	0	hSpCas9	negative selection	11214305
19226745	19226768	19	+	28162770	OCIAML5	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	-0.04820909304262	[58]	[102]	0	hSpCas9	negative selection	11214306
19238371	19238394	19	+	28162770	OCIAML5	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-1.5750592224775988	[136]	[82]	-7	hSpCas9	negative selection	11214307
19219009	19219032	19	-	28162770	OCIAML5	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-0.7849523750054599	[104]	[109]	-5	hSpCas9	negative selection	11214308
19219065	19219088	19	+	28162770	OCIAML5	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-1.1079054752935868	[79]	[66]	-6	hSpCas9	negative selection	11214309
19224066	19224089	19	-	28162770	OCIAML5	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-0.48433478636351013	[30]	[39]	-3	hSpCas9	negative selection	11214310
19224119	19224142	19	-	28162770	OCIAML5	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	-1.5983099786182138	[51]	[30]	-7	hSpCas9	negative selection	11214311
19224342	19224365	19	+	28162770	OCIAML5	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	-0.8610834442214307	[320]	[318]	-5	hSpCas9	negative selection	11214312
19225061	19225084	19	-	28162770	OCIAML5	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	-0.17275576911800083	[290]	[465]	-1	hSpCas9	negative selection	11214313
19226580	19226603	19	+	28162770	OCIAML5	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-7.874434383892451	[129]	[0]	-9	hSpCas9	negative selection	11214314
19227644	19227667	19	-	28162770	EOL1	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	0.6295029708341198	[637]	[519]	5	hSpCas9	negative selection	11383671
19226745	19226768	19	+	28162770	EOL1	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	1.0323510611050497	[115]	[124]	8	hSpCas9	negative selection	11383672
19238371	19238394	19	+	28162770	EOL1	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-1.0046119878790165	[456]	[119]	-6	hSpCas9	negative selection	11383673
19219009	19219032	19	-	28162770	EOL1	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	0.7866198633372075	[339]	[308]	7	hSpCas9	negative selection	11383674
19219065	19219088	19	+	28162770	EOL1	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-0.26511344793303987	[275]	[120]	-2	hSpCas9	negative selection	11383675
19224066	19224089	19	-	28162770	EOL1	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-2.204735245374432	[139]	[15]	-8	hSpCas9	negative selection	11383676
19224119	19224142	19	-	28162770	EOL1	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	1.169170140290448	[91]	[108]	8	hSpCas9	negative selection	11383677
19224342	19224365	19	+	28162770	EOL1	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	-0.5319224466956555	[729]	[265]	-4	hSpCas9	negative selection	11383678
19225061	19225084	19	-	28162770	EOL1	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	0.40517361247695516	[601]	[419]	3	hSpCas9	negative selection	11383679
19226580	19226603	19	+	28162770	EOL1	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-1.1994409457049189	[169]	[38]	-7	hSpCas9	negative selection	11383680
19227644	19227667	19	-	28162770	MOLM13	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	0.7291215447443873	[533]	[639]	5	hSpCas9	negative selection	11553037
19226745	19226768	19	+	28162770	MOLM13	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	-0.38010752501037115	[161]	[89]	-2	hSpCas9	negative selection	11553038
19238371	19238394	19	+	28162770	MOLM13	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-1.1086853336838587	[342]	[114]	-5	hSpCas9	negative selection	11553039
19219009	19219032	19	-	28162770	MOLM13	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-2.067032436676982	[254]	[43]	-7	hSpCas9	negative selection	11553040
19219065	19219088	19	+	28162770	MOLM13	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-0.6267474925934964	[251]	[117]	-4	hSpCas9	negative selection	11553041
19224066	19224089	19	-	28162770	MOLM13	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	0.1495279016774087	[100]	[80]	1	hSpCas9	negative selection	11553042
19224119	19224142	19	-	28162770	MOLM13	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	-1.876939115452862	[126]	[24]	-7	hSpCas9	negative selection	11553043
19224342	19224365	19	+	28162770	MOLM13	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	-0.2161812641895018	[722]	[449]	-1	hSpCas9	negative selection	11553044
19225061	19225084	19	-	28162770	MOLM13	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	0.45574029887846257	[476]	[472]	3	hSpCas9	negative selection	11553045
19226580	19226603	19	+	28162770	MOLM13	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-6.941501554593123	[169]	[0]	-9	hSpCas9	negative selection	11553046
19227644	19227667	19	-	28162770	HEL	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	0.2247956015461019	[496]	[371]	1	hSpCas9	negative selection	11722403
19226745	19226768	19	+	28162770	HEL	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	0.8014365780194154	[85]	[95]	7	hSpCas9	negative selection	11722404
19238371	19238394	19	+	28162770	HEL	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-0.3478624699973935	[305]	[153]	-2	hSpCas9	negative selection	11722405
19219009	19219032	19	-	28162770	HEL	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	0.2779745392027368	[187]	[145]	2	hSpCas9	negative selection	11722406
19219065	19219088	19	+	28162770	HEL	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-0.11910143080487845	[194]	[114]	-1	hSpCas9	negative selection	11722407
19224066	19224089	19	-	28162770	HEL	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-0.4447240092499827	[84]	[39]	-3	hSpCas9	negative selection	11722408
19224119	19224142	19	-	28162770	HEL	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	0.2138955331964827	[69]	[51]	1	hSpCas9	negative selection	11722409
19224342	19224365	19	+	28162770	HEL	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	0.3571029972294306	[578]	[474]	3	hSpCas9	negative selection	11722410
19225061	19225084	19	-	28162770	HEL	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	1.0185169008319734	[446]	[579]	8	hSpCas9	negative selection	11722411
19226580	19226603	19	+	28162770	HEL	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-4.576429688461804	[148]	[3]	-9	hSpCas9	negative selection	11722412
19227644	19227667	19	-	28162770	MV411	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	0.3680912898701242	[320]	[348]	3	hSpCas9	negative selection	11891769
19226745	19226768	19	+	28162770	MV411	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	-0.5930842352100283	[76]	[42]	-4	hSpCas9	negative selection	11891770
19238371	19238394	19	+	28162770	MV411	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-0.7116644180352258	[312]	[160]	-5	hSpCas9	negative selection	11891771
19219009	19219032	19	-	28162770	MV411	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-0.30373663648209753	[210]	[143]	-2	hSpCas9	negative selection	11891772
19219065	19219088	19	+	28162770	MV411	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-0.026737412656218762	[103]	[85]	0	hSpCas9	negative selection	11891773
19224066	19224089	19	-	28162770	MV411	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-6.39641863899195	[99]	[0]	-9	hSpCas9	negative selection	11891774
19224119	19224142	19	-	28162770	MV411	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	0.43506455395854654	[107]	[122]	4	hSpCas9	negative selection	11891775
19224342	19224365	19	+	28162770	MV411	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	-0.8812046006563294	[421]	[192]	-6	hSpCas9	negative selection	11891776
19225061	19225084	19	-	28162770	MV411	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	0.0003966675264047703	[304]	[256]	0	hSpCas9	negative selection	11891777
19226580	19226603	19	+	28162770	MV411	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-2.5033338429084613	[174]	[25]	-8	hSpCas9	negative selection	11891778
19227644	19227667	19	-	28162770	MONOMAC1	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	0.12489124782780858	[255]	[319]	1	hSpCas9	negative selection	12061135
19226745	19226768	19	+	28162770	MONOMAC1	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	-0.19703684705955393	[63]	[63]	-2	hSpCas9	negative selection	12061136
19238371	19238394	19	+	28162770	MONOMAC1	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-0.4865434642545386	[164]	[134]	-4	hSpCas9	negative selection	12061137
19219009	19219032	19	-	28162770	MONOMAC1	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-0.34142675639472836	[146]	[132]	-3	hSpCas9	negative selection	12061138
19219065	19219088	19	+	28162770	MONOMAC1	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	0.46983685144822007	[96]	[153]	4	hSpCas9	negative selection	12061139
19224066	19224089	19	-	28162770	MONOMAC1	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	0.6394644206575667	[41]	[74]	6	hSpCas9	negative selection	12061140
19224119	19224142	19	-	28162770	MONOMAC1	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	-0.16789050140003714	[48]	[49]	-1	hSpCas9	negative selection	12061141
19224342	19224365	19	+	28162770	MONOMAC1	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	-0.1333421717421639	[287]	[300]	-1	hSpCas9	negative selection	12061142
19225061	19225084	19	-	28162770	MONOMAC1	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	0.694149665801521	[233]	[433]	6	hSpCas9	negative selection	12061143
19226580	19226603	19	+	28162770	MONOMAC1	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-1.0252704987930736	[86]	[48]	-7	hSpCas9	negative selection	12061144
19227644	19227667	19	-	28162770	OCIAML2	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	-0.1645993572350074	[72]	[360]	-1	hSpCas9	negative selection	12230501
19226745	19226768	19	+	28162770	OCIAML2	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	1.0863182993093983	[12]	[152]	9	hSpCas9	negative selection	12230502
19238371	19238394	19	+	28162770	OCIAML2	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-1.1634483157239852	[58]	[145]	-6	hSpCas9	negative selection	12230503
19219009	19219032	19	-	28162770	OCIAML2	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-0.7902477594423224	[38]	[124]	-5	hSpCas9	negative selection	12230504
19219065	19219088	19	+	28162770	OCIAML2	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	-0.3114312303929073	[29]	[133]	-3	hSpCas9	negative selection	12230505
19224066	19224089	19	-	28162770	OCIAML2	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-3.011198206604864	[15]	[10]	-9	hSpCas9	negative selection	12230506
19224119	19224142	19	-	28162770	OCIAML2	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	-0.30070482379984886	[9]	[44]	-2	hSpCas9	negative selection	12230507
19224342	19224365	19	+	28162770	OCIAML2	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	0.27187395246547497	[77]	[521]	2	hSpCas9	negative selection	12230508
19225061	19225084	19	-	28162770	OCIAML2	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	-0.07831240246340088	[63]	[335]	0	hSpCas9	negative selection	12230509
19226580	19226603	19	+	28162770	OCIAML2	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-2.608133348992096	[21]	[19]	-8	hSpCas9	negative selection	12230510
19227644	19227667	19	-	28162770	OCIAML3	viability	GAGAGGCAGGGAATACACCTTGG	NCAN	ENSG00000130287	0.017921907997262343	[105]	[323]	0	hSpCas9	negative selection	12399867
19226745	19226768	19	+	28162770	OCIAML3	viability	GGAAGTGTGGCTAAGCACGGTGG	NCAN	ENSG00000130287	-0.5326070956600202	[22]	[47]	-4	hSpCas9	negative selection	12399868
19238371	19238394	19	+	28162770	OCIAML3	viability	GACCAGCGTCCACTCACCGGAGG	NCAN	ENSG00000130287	-0.17897014104531922	[62]	[167]	-1	hSpCas9	negative selection	12399869
19219009	19219032	19	-	28162770	OCIAML3	viability	GCAGGGTAAAGAGACAGGGCAGG	NCAN	ENSG00000130287	-0.734870176164013	[42]	[77]	-5	hSpCas9	negative selection	12399870
19219065	19219088	19	+	28162770	OCIAML3	viability	GGATAAAGTGGACCAAGGTGCGG	NCAN	ENSG00000130287	0.0743708685846306	[27]	[88]	0	hSpCas9	negative selection	12399871
19224066	19224089	19	-	28162770	OCIAML3	viability	GGCCTCCTGGGCCTCAGCGAAGG	NCAN	ENSG00000130287	-1.1651643415202888	[25]	[34]	-7	hSpCas9	negative selection	12399872
19224119	19224142	19	-	28162770	OCIAML3	viability	AAGGCAGCCTGTAGATGCCGAGG	NCAN	ENSG00000130287	0.05806905625553016	[27]	[87]	0	hSpCas9	negative selection	12399873
19224342	19224365	19	+	28162770	OCIAML3	viability	CGACCGTAGCAGCCTTCCAGGGG	NCAN	ENSG00000130287	0.7523734982877381	[116]	[594]	6	hSpCas9	negative selection	12399874
19225061	19225084	19	-	28162770	OCIAML3	viability	CAGGTGCAGCTGTCCCACCGAGG	NCAN	ENSG00000130287	0.4905258698875048	[115]	[491]	4	hSpCas9	negative selection	12399875
19226580	19226603	19	+	28162770	OCIAML3	viability	ACTGGAGCCCACCCTGGAGGAGG	NCAN	ENSG00000130287	-3.3665971442210907	[40]	[11]	-9	hSpCas9	negative selection	12399876