Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 10016
• Symbol: PDCD6
• Description: programmed cell death 6

DataSource: http://genomecrispr.dkfz.de/#!/results/PDCD6

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
271725	271748	5	-	26472758	Jiyoye	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-0.7835081801032363	[209]	[91]	-5	hSpCas9	negative selection	117817
271800	271823	5	+	26472758	Jiyoye	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.8980395079798278	[453]	[637]	6	hSpCas9	negative selection	117819
271725	271748	5	-	26472758	KBM7	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-0.829695307019225	[823,687]	[139,251]	-6	hSpCas9	negative selection	308935
271800	271823	5	+	26472758	KBM7	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.3759428226533359	[2618,2235]	[1751,1229]	4	hSpCas9	negative selection	308937
271725	271748	5	-	26472758	Raji	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-0.6100292613712062	[341]	[51]	-5	hSpCas9	negative selection	500053
271800	271823	5	+	26472758	Raji	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.18912668481513584	[891]	[235]	1	hSpCas9	negative selection	500055
271725	271748	5	-	26472758	K562	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-0.8033344037819212	[644]	[311]	-5	hSpCas9	negative selection	691171
271800	271823	5	+	26472758	K562	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.3555777884926936	[1672]	[1806]	2	hSpCas9	negative selection	691173
271718	271741	5	-	24336569	HL60	viability	CGGTAAGAGTAGGCGGCCATGGG	PDCD6	ENSG00000249915	0.3115470923199486	[494]	[1299]	3	hSpCas9	negative selection	2283223
271755	271778	5	-	24336569	HL60	viability	GCCTGCAGCAGGCCCAGGGCCGG	PDCD6	ENSG00000249915	-0.6580492528121145	[600]	[805]	-5	hSpCas9	negative selection	2283224
271718	271741	5	-	24336569	KBM7	viability	CGGTAAGAGTAGGCGGCCATGGG	PDCD6	ENSG00000249915	-0.5446466145090474	[729]	[1364]	-4	hSpCas9	negative selection	2350400
271755	271778	5	-	24336569	KBM7	viability	GCCTGCAGCAGGCCCAGGGCCGG	PDCD6	ENSG00000249915	-0.12224047349886821	[337]	[846]	-1	hSpCas9	negative selection	2350401
304045	304068	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGTGGTTTTCTAGACACTCCAGG	PDCD6	ENSG00000249915	1.3952183349278156	[1101,425]	[112,791]	5	dCas9-VP64	positive selection	2452282
304027	304050	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGGCAGCCGACACGTCACCTGG	PDCD6	ENSG00000249915	0.13112022966096193	[532,251]	[56,133]	0	dCas9-VP64	positive selection	2452284
303977	304000	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGCAGGGTGTGAACCCACCAGG	PDCD6	ENSG00000249915	6.206546620039431	[117,75]	[88,3190]	9	dCas9-VP64	positive selection	2452285
290522	290545	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTACCACCAACCCTCCAACATGG	PDCD6	ENSG00000249915	2.2176916459102958	[147,55]	[193,6]	7	dCas9-VP64	positive selection	2471187
304045	304068	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGTGGTTTTCTAGACACTCCAGG	PDCD6	ENSG00000249915	0.09498543722859931	[247,118]	[69,58]	0	dCas9-VP64	positive selection	2547537
304027	304050	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGGCAGCCGACACGTCACCTGG	PDCD6	ENSG00000249915	1.166837590289494	[275,243]	[80,292]	7	dCas9-VP64	positive selection	2547539
303977	304000	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGCAGGGTGTGAACCCACCAGG	PDCD6	ENSG00000249915	5.615364120530151	[50,40]	[26,1422]	9	dCas9-VP64	positive selection	2547540
290522	290545	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTACCACCAACCCTCCAACATGG	PDCD6	ENSG00000249915	-1.2614224522991961	[121,208]	[28,14]	-9	dCas9-VP64	positive selection	2566442
271801	271824	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCTCTGGAAAACGTTCCACAGG	PDCD6	ENSG00000249915	0.18536394465660977	[3,2]	[2,3]	4	hSpCas9	positive selection	3010304
271759	271782	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCGCGCCTGCAGCAGGCCCAGGG	PDCD6	ENSG00000249915	-0.9307105648950681	[3,3]	[1,0]	-9	hSpCas9	positive selection	3010305
271725	271748	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCGCCTACTCTTACCGCCCCGG	PDCD6	ENSG00000249915	0.2725691382893123	[3,3]	[2,4]	6	hSpCas9	positive selection	3010306
271725	271748	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	0.15566585225277535	[3,3]	[2,4]	3	hSpCas9	positive selection	3010307
271801	271824	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCTCTGGAAAACGTTCCACAGG	PDCD6	ENSG00000249915	-0.6293856118996637	[3,3]	[1,1]	-8	hSpCas9	positive selection	3078162
271759	271782	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCGCGCCTGCAGCAGGCCCAGGG	PDCD6	ENSG00000249915	-0.07227193025595069	[3,3]	[3,1]	-1	hSpCas9	positive selection	3078163
271725	271748	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCGCCTACTCTTACCGCCCCGG	PDCD6	ENSG00000249915	0.14597797209726454	[3,3]	[3,1]	2	hSpCas9	positive selection	3078164
271725	271748	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-0.6595232868143481	[3,3]	[2,0]	-8	hSpCas9	positive selection	3078165
272746	272769	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.2425196756373702	[180,180]	[0,0]	-1	hSpCas9	positive selection	3385067
272704	272727	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	1.529405756882636	[52,52]	[0,0]	6	hSpCas9	positive selection	3385068
271801	271824	5	-	26780180	HT29	viability (Avana library 4 designs)	ACCTCTGGAAAACGTTCCACAGG	PDCD6	ENSG00000249915	1.00168760499473	[]	[]	4	hSpCas9	negative selection	3448355
271759	271782	5	-	26780180	HT29	viability (Avana library 4 designs)	CCGCGCCTGCAGCAGGCCCAGGG	PDCD6	ENSG00000249915	2.9597833892222	[]	[]	8	hSpCas9	negative selection	3448356
271724	271747	5	+	26780180	HT29	viability (Avana library 4 designs)	GCCGCCTACTCTTACCGCCCCGG	PDCD6	ENSG00000249915	2.86456846733868	[]	[]	8	hSpCas9	negative selection	3448357
271725	271748	5	-	26780180	HT29	viability (Avana library 4 designs)	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	2.80193185444493	[]	[]	8	hSpCas9	negative selection	3448358
271725	271748	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-0.208087414893195	[]	[]	0	hSpCas9	negative selection	3542599
271759	271782	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCGCGCCTGCAGCAGGCCCAGGG	PDCD6	ENSG00000249915	-1.06448940766745	[]	[]	-1	hSpCas9	negative selection	3542600
271801	271824	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCTCTGGAAAACGTTCCACAGG	PDCD6	ENSG00000249915	-6.54282601716816	[]	[]	-6	hSpCas9	negative selection	3542601
271724	271747	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCGCCTACTCTTACCGCCCCGG	PDCD6	ENSG00000249915	-5.99792928233494	[]	[]	-6	hSpCas9	negative selection	3542602
271732	271755	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTCTTACCGCCCCGGCCCTGGGG	PDCD6	ENSG00000249915	3.17497301175137	[]	[]	5	hSpCas9	negative selection	3542603
271747	271770	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGGCCCAGGGCCGGCCCCAGGG	PDCD6	ENSG00000249915	8.15278044756003	[]	[]	9	hSpCas9	negative selection	3542604
271725	271748	5	-	26780180	A375	viability (Avana lentiGuide)	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	5.45377976513886	[]	[]	5	hSpCas9	negative selection	3651258
271759	271782	5	-	26780180	A375	viability (Avana lentiGuide)	CCGCGCCTGCAGCAGGCCCAGGG	PDCD6	ENSG00000249915	20.9168777873085	[]	[]	8	hSpCas9	negative selection	3651259
271801	271824	5	-	26780180	A375	viability (Avana lentiGuide)	ACCTCTGGAAAACGTTCCACAGG	PDCD6	ENSG00000249915	7.44086330711068	[]	[]	6	hSpCas9	negative selection	3651260
271724	271747	5	+	26780180	A375	viability (Avana lentiGuide)	GCCGCCTACTCTTACCGCCCCGG	PDCD6	ENSG00000249915	11.2947157711121	[]	[]	7	hSpCas9	negative selection	3651261
271732	271755	5	+	26780180	A375	viability (Avana lentiGuide)	CTCTTACCGCCCCGGCCCTGGGG	PDCD6	ENSG00000249915	-0.257883582443083	[]	[]	0	hSpCas9	negative selection	3651262
271747	271770	5	-	26780180	A375	viability (Avana lentiGuide)	CAGGCCCAGGGCCGGCCCCAGGG	PDCD6	ENSG00000249915	-3.82685073453121	[]	[]	-6	hSpCas9	negative selection	3651263
271725	271748	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-0.10535202786458536	[5]	[5,4]	-2	hSpCas9	positive selection	3759917
271759	271782	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCGCGCCTGCAGCAGGCCCAGGG	PDCD6	ENSG00000249915	0.00315040629030495	[5]	[5,4]	0	hSpCas9	positive selection	3759918
271801	271824	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCTCTGGAAAACGTTCCACAGG	PDCD6	ENSG00000249915	-0.5414036474059261	[4]	[2,2]	-7	hSpCas9	positive selection	3759919
271724	271747	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCGCCTACTCTTACCGCCCCGG	PDCD6	ENSG00000249915	-0.3111139534064912	[5]	[4,3]	-5	hSpCas9	positive selection	3759920
271732	271755	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCTTACCGCCCCGGCCCTGGGG	PDCD6	ENSG00000249915	0.263163421614935	[5]	[7,6]	7	hSpCas9	positive selection	3759921
271747	271770	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGGCCCAGGGCCGGCCCCAGGG	PDCD6	ENSG00000249915	0.38322423697531516	[5]	[6,6]	9	hSpCas9	positive selection	3759922
271725	271748	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-0.35876698461211065	[5]	[2,4]	-5	hSpCas9	positive selection	3868524
271759	271782	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCGCGCCTGCAGCAGGCCCAGGG	PDCD6	ENSG00000249915	-1.8934376873311562	[6]	[0,0]	-9	hSpCas9	positive selection	3868525
271801	271824	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCTCTGGAAAACGTTCCACAGG	PDCD6	ENSG00000249915	-0.5982962247381449	[4]	[3,0]	-6	hSpCas9	positive selection	3868526
271724	271747	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCGCCTACTCTTACCGCCCCGG	PDCD6	ENSG00000249915	-0.2771434906598577	[6]	[4,3]	-4	hSpCas9	positive selection	3868527
271732	271755	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCTTACCGCCCCGGCCCTGGGG	PDCD6	ENSG00000249915	0.2776916777730196	[6]	[7,6]	7	hSpCas9	positive selection	3868528
271747	271770	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGGCCCAGGGCCGGCCCCAGGG	PDCD6	ENSG00000249915	0.28169393598204495	[5]	[6,5]	7	hSpCas9	positive selection	3868529
272746	272769	5	-	26780180	A375	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	1.55370263586665	[]	[]	8	hSpCas9	negative selection	3979300
272704	272727	5	+	26780180	A375	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	1.45706582865322	[]	[]	8	hSpCas9	negative selection	3979301
272746	272769	5	-	26780180	HT29	viability (GeCKOv2 library)	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	2.14439302015461	[]	[]	9	hSpCas9	negative selection	4087266
272704	272727	5	+	26780180	HT29	viability (GeCKOv2 library)	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	1.17554459009697	[]	[]	5	hSpCas9	negative selection	4087267
272746	272769	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.6098463163692969	[3]	[2,0]	-8	hSpCas9	positive selection	4353641
272704	272727	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.280359324231672	[1]	[0,1]	-5	hSpCas9	positive selection	4353642
271801	271823	5	+	27760321	OCIAML3	viability	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	-0.4199045477978138	[412,286]	[170,242]	-4	hSpCas9	negative selection	4426448
271816	271838	5	-	27760321	OCIAML3	viability	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	-0.7711747012230925	[741,759]	[296,408]	-6	hSpCas9	negative selection	4426449
272705	272727	5	+	27760321	OCIAML3	viability	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-3.4710052556090902	[18,9]	[0,0]	-9	hSpCas9	negative selection	4426450
272746	272768	5	-	27760321	OCIAML3	viability	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.245852048789979	[465,406]	[150,133]	-8	hSpCas9	negative selection	4426451
271801	271823	5	+	27760321	OCIAML2	viability	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	-0.433720487082254	[412,286]	[217,192]	-5	hSpCas9	negative selection	4509911
271816	271838	5	-	27760321	OCIAML2	viability	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	-0.2656413241694382	[741,759]	[431,606]	-3	hSpCas9	negative selection	4509912
272705	272727	5	+	27760321	OCIAML2	viability	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-1.0478562070107484	[18,9]	[8,0]	-7	hSpCas9	negative selection	4509913
272746	272768	5	-	27760321	OCIAML2	viability	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.0887066839026787	[465,406]	[153,180]	-7	hSpCas9	negative selection	4509914
271801	271823	5	+	27760321	MV411	viability	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	-1.4846184330310817	[412,286]	[63,107]	-7	hSpCas9	negative selection	4593374
271816	271838	5	-	27760321	MV411	viability	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	-0.013001683588398372	[741,759]	[535,428]	0	hSpCas9	negative selection	4593375
272705	272727	5	+	27760321	MV411	viability	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-3.2259266866944083	[18,9]	[0,0]	-9	hSpCas9	negative selection	4593376
272746	272768	5	-	27760321	MV411	viability	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.0156439076088712	[465,406]	[78,236]	-6	hSpCas9	negative selection	4593377
271801	271823	5	+	27760321	HL60	viability	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	-0.3957708329833584	[412,286]	[158,273]	-4	hSpCas9	negative selection	4676837
271816	271838	5	-	27760321	HL60	viability	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	-0.06427628315519318	[741,759]	[613,562]	0	hSpCas9	negative selection	4676838
272705	272727	5	+	27760321	HL60	viability	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	0.4244828389566644	[18,9]	[16,13]	5	hSpCas9	negative selection	4676839
272746	272768	5	-	27760321	HL60	viability	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.4758450231547581	[465,406]	[265,244]	-5	hSpCas9	negative selection	4676840
271801	271823	5	+	27760321	HT1080	viability	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	-1.1673824213479644	[286,223]	[51,37]	-4	hSpCas9	negative selection	4760300
271816	271838	5	-	27760321	HT1080	viability	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	-1.7749779151564788	[759,592]	[104,49]	-6	hSpCas9	negative selection	4760301
272705	272727	5	+	27760321	HT1080	viability	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-1.8443172389209588	[9,7]	[0,0]	-6	hSpCas9	negative selection	4760302
272746	272768	5	-	27760321	HT1080	viability	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.9822987157343566	[406,317]	[5,69]	-6	hSpCas9	negative selection	4760303
271801	271823	5	+	27760321	HT29	viability after 7 days	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.8284843123980444	[286,223]	[590,565,592]	9	hSpCas9	negative selection	4843763
271816	271838	5	-	27760321	HT29	viability after 7 days	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	-0.22088314904884032	[759,592]	[1080,631,577]	-3	hSpCas9	negative selection	4843764
272705	272727	5	+	27760321	HT29	viability after 7 days	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	0.7100097042031939	[9,7]	[17,28,9]	9	hSpCas9	negative selection	4843765
272746	272768	5	-	27760321	HT29	viability after 7 days	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.821298400187095	[406,317]	[415,206,191]	-8	hSpCas9	negative selection	4843766
271801	271823	5	+	27760321	HT29	viability after 25 days	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.44699535954156844	[286,223]	[347,309,554]	5	hSpCas9	negative selection	4927226
271816	271838	5	-	27760321	HT29	viability after 25 days	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	0.006130708263853535	[759,592]	[956,562,798]	0	hSpCas9	negative selection	4927227
272705	272727	5	+	27760321	HT29	viability after 25 days	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.1009911094690974	[9,7]	[17,2,6]	-1	hSpCas9	negative selection	4927228
272746	272768	5	-	27760321	HT29	viability after 25 days	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.2878822402482974	[406,317]	[225,145,128]	-7	hSpCas9	negative selection	4927229
271801	271823	5	+	27760321	HT29	viability after 22 days	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.575249129448778	[286,223]	[336,338,648]	6	hSpCas9	negative selection	5010689
271816	271838	5	-	27760321	HT29	viability after 22 days	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	-0.29707455448565123	[759,592]	[703,430,773]	-3	hSpCas9	negative selection	5010690
272705	272727	5	+	27760321	HT29	viability after 22 days	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	1.1070577777576869	[9,7]	[8,4,53]	9	hSpCas9	negative selection	5010691
272746	272768	5	-	27760321	HT29	viability after 22 days	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.4397708762048333	[406,317]	[178,212,69]	-7	hSpCas9	negative selection	5010692
271801	271823	5	+	27760321	HT29	viability after 19 days	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.412513900713055	[286,223]	[338,317,499]	4	hSpCas9	negative selection	5094152
271816	271838	5	-	27760321	HT29	viability after 19 days	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	-0.10334914822779973	[759,592]	[800,658,708]	-1	hSpCas9	negative selection	5094153
272705	272727	5	+	27760321	HT29	viability after 19 days	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	2.814664528397878	[9,7]	[14,136,59]	9	hSpCas9	negative selection	5094154
272746	272768	5	-	27760321	HT29	viability after 19 days	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.9167944224974802	[406,317]	[220,90,31]	-8	hSpCas9	negative selection	5094155
271801	271823	5	+	27760321	HT29	viability after 16 days	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	-0.1366677063845641	[286,223]	[241,271,263]	-1	hSpCas9	negative selection	5177615
271816	271838	5	-	27760321	HT29	viability after 16 days	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	-0.10471019567204087	[759,592]	[966,487,686]	-1	hSpCas9	negative selection	5177616
272705	272727	5	+	27760321	HT29	viability after 16 days	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	1.1682752746672467	[9,7]	[33,24,9]	9	hSpCas9	negative selection	5177617
272746	272768	5	-	27760321	HT29	viability after 16 days	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.6240178349082635	[406,317]	[260,91,54]	-8	hSpCas9	negative selection	5177618
271801	271823	5	+	27760321	HT29	viability after 13 days	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.6830852840563939	[286,223]	[324,405,683]	8	hSpCas9	negative selection	5261078
271816	271838	5	-	27760321	HT29	viability after 13 days	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	-0.0009720600547844516	[759,592]	[986,679,690]	0	hSpCas9	negative selection	5261079
272705	272727	5	+	27760321	HT29	viability after 13 days	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.9458776775543516	[9,7]	[4,0,9]	-7	hSpCas9	negative selection	5261080
272746	272768	5	-	27760321	HT29	viability after 13 days	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.127187968927104	[406,317]	[133,255,187]	-7	hSpCas9	negative selection	5261081
271801	271823	5	+	27760321	HT29	viability after 10 days	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.8675307014154491	[286,223]	[431,768,550]	9	hSpCas9	negative selection	5344541
271816	271838	5	-	27760321	HT29	viability after 10 days	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	-0.3297431497545523	[759,592]	[800,532,677]	-4	hSpCas9	negative selection	5344542
272705	272727	5	+	27760321	HT29	viability after 10 days	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	1.8950314196685745	[9,7]	[62,0,59]	9	hSpCas9	negative selection	5344543
272746	272768	5	-	27760321	HT29	viability after 10 days	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.3977739423856296	[406,317]	[381,393,257]	-5	hSpCas9	negative selection	5344544
271801	271823	5	+	27760321	MOLM13	viability	CCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	-0.805305076672882	[412,286]	[108,113]	-5	hSpCas9	negative selection	5428004
271816	271838	5	-	27760321	MOLM13	viability	CGGTGCCAGGCCGCACCTCTGG	PDCD6	ENSG00000249915	-0.0076395441993718505	[741,759]	[385,454]	0	hSpCas9	negative selection	5428005
272705	272727	5	+	27760321	MOLM13	viability	TTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-2.999869873866813	[18,9]	[0,0]	-9	hSpCas9	negative selection	5428006
272746	272768	5	-	27760321	MOLM13	viability	GAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.1171204445433245	[465,406]	[122,104]	-6	hSpCas9	negative selection	5428007
271652	271675	5	+	27661255	K562	viability	GGAAGCGGAGTCGGCCTGAGAGG	PDCD6	ENSG00000249915	0.14162615613530538	[1026,1155]	[989,933]	5	dCas9-KRAB	negative selection	5500817
271666	271689	5	-	27661255	K562	viability	GCAGCGACGAGAGACCTCTCAGG	PDCD6	ENSG00000249915	0.12655011895790702	[132,200]	[136,150]	4	dCas9-KRAB	negative selection	5500818
271901	271924	5	-	27661255	K562	viability	GCAGTAGAACCGGCAGGGAACGG	PDCD6	ENSG00000249915	-0.019900889709017378	[257,265]	[235,180]	-1	dCas9-KRAB	negative selection	5500819
271911	271934	5	-	27661255	K562	viability	GGAGGAGGCCGCAGTAGAACCGG	PDCD6	ENSG00000249915	0.06565458598503275	[766,824]	[764,578]	2	dCas9-KRAB	negative selection	5500820
271926	271949	5	-	27661255	K562	viability	GACCCGACAGGGGACGGAGGAGG	PDCD6	ENSG00000249915	-0.7653926223415897	[294,219]	[112,128]	-8	dCas9-KRAB	negative selection	5500821
271936	271959	5	-	27661255	K562	viability	GGCCGCGGGGGACCCGACAGGGG	PDCD6	ENSG00000249915	0.09406072551040823	[570,463]	[518,377]	3	dCas9-KRAB	negative selection	5500822
272746	272769	5	-	27260156	BXPC3	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.656488993113979	[501]	[298,304,408,321]	-8	hSpCas9	negative selection	5626101
272704	272727	5	+	27260156	BXPC3	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.9592557168021898	[189]	[100,106,86,113]	-9	hSpCas9	negative selection	5626102
272746	272769	5	-	27260156	A673	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.32893584798861997	[501]	[595,373,552,406]	-7	hSpCas9	negative selection	5747352
272704	272727	5	+	27260156	A673	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.40127525385491647	[189]	[221,102,110,267]	-7	hSpCas9	negative selection	5747353
272746	272769	5	-	27260156	A375	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.8454292284755082	[501]	[425,167,364,323]	-8	hSpCas9	negative selection	5868603
272704	272727	5	+	27260156	A375	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.7643299716339182	[189]	[111,85,170,144]	-7	hSpCas9	negative selection	5868604
272746	272769	5	-	27260156	COLO741	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.7898790961285842	[501]	[384,422,309]	-9	hSpCas9	negative selection	5989854
272704	272727	5	+	27260156	COLO741	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.9782023488778351	[189]	[77,168,118]	-9	hSpCas9	negative selection	5989855
272746	272769	5	-	27260156	CAL120	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.31078099769321677	[501]	[566,326,623]	-4	hSpCas9	negative selection	6111105
272704	272727	5	+	27260156	CAL120	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.13288398984497607	[189]	[249,243,158]	-2	hSpCas9	negative selection	6111106
272746	272769	5	-	27260156	CADOES1	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.38495286968989073	[501]	[360,422,347,295]	-6	hSpCas9	negative selection	6232356
272704	272727	5	+	27260156	CADOES1	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.5090789454735909	[189]	[156,118,85,134]	-7	hSpCas9	negative selection	6232357
272746	272769	5	-	27260156	EWS502	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.6092149256055838	[501]	[337,260,325,481]	-7	hSpCas9	negative selection	6353607
272704	272727	5	+	27260156	EWS502	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.6150996934806117	[189]	[57,132,244,96]	-7	hSpCas9	negative selection	6353608
272746	272769	5	-	27260156	EW8	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.47798513188494895	[501]	[391,336,136,338]	-7	hSpCas9	negative selection	6474858
272704	272727	5	+	27260156	EW8	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.5967595148590135	[189]	[142,111,75,84]	-8	hSpCas9	negative selection	6474859
272746	272769	5	-	27260156	CORL105	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.61369354816289	[501]	[354,439,276,444]	-8	hSpCas9	negative selection	6596109
272704	272727	5	+	27260156	CORL105	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.26781606935266256	[189]	[171,255,188,120]	-5	hSpCas9	negative selection	6596110
272746	272769	5	-	27260156	HS294T	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.31373275226257036	[501]	[262,83,108,160]	-4	hSpCas9	negative selection	6717360
272704	272727	5	+	27260156	HS294T	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.6862276760599064	[189]	[50,40,34,56]	-7	hSpCas9	negative selection	6717361
272746	272769	5	-	27260156	HCC44	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.9798507985410715	[501]	[228,237,546,184]	-8	hSpCas9	negative selection	6838611
272704	272727	5	+	27260156	HCC44	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.6767839884337545	[189]	[66,243,144,62]	-7	hSpCas9	negative selection	6838612
272746	272769	5	-	27260156	G402	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.7885857677785921	[501]	[338,272,293,496]	-7	hSpCas9	negative selection	6959862
272704	272727	5	+	27260156	G402	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.09428739109423234	[189]	[111,352,187,207]	-1	hSpCas9	negative selection	6959863
272746	272769	5	-	27260156	L33	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.7632531131410366	[501]	[316,124,211,223]	-9	hSpCas9	negative selection	7081113
272704	272727	5	+	27260156	L33	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.719368608773205	[189]	[103,34,100,111]	-9	hSpCas9	negative selection	7081114
272746	272769	5	-	27260156	K562	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.085815284670952	[501]	[211,201,191,229]	-8	hSpCas9	negative selection	7202364
272704	272727	5	+	27260156	K562	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.20291636915993982	[189]	[391,108,45,65]	-3	hSpCas9	negative selection	7202365
272746	272769	5	-	27260156	HT29	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.7057404676583343	[501]	[505,279,452,269]	-8	hSpCas9	negative selection	7323615
272704	272727	5	+	27260156	HT29	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.24829981602747342	[189]	[244,207,201,133]	-5	hSpCas9	negative selection	7323616
272746	272769	5	-	27260156	MHHES1	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.4309837251628427	[501]	[570,535,269,338]	-7	hSpCas9	negative selection	7444866
272704	272727	5	+	27260156	MHHES1	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.2883563663926503	[189]	[215,255,136,114]	-5	hSpCas9	negative selection	7444867
272746	272769	5	-	27260156	MEWO	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.26969108347407905	[501]	[376,430,357]	-5	hSpCas9	negative selection	7566117
272704	272727	5	+	27260156	MEWO	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.5041014450245171	[189]	[191,103,92]	-8	hSpCas9	negative selection	7566118
272746	272769	5	-	27260156	LNCAPCLONEFGC	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.8471510970648652	[501]	[152,324,251,277]	-8	hSpCas9	negative selection	7687368
272704	272727	5	+	27260156	LNCAPCLONEFGC	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.6926772780307728	[189]	[51,151,106,112]	-8	hSpCas9	negative selection	7687369
272746	272769	5	-	27260156	PANC0327	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.9451537483689524	[501]	[321,212,144,255]	-8	hSpCas9	negative selection	7808619
272704	272727	5	+	27260156	PANC0327	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.15386770985048437	[189]	[319,46,103,162]	-2	hSpCas9	negative selection	7808620
272746	272769	5	-	27260156	NCIH2009	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.1808137480506808	[501]	[352,321,260]	-8	hSpCas9	negative selection	7929870
272704	272727	5	+	27260156	NCIH2009	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.9753987895289757	[189]	[128,58,216]	-8	hSpCas9	negative selection	7929871
272746	272769	5	-	27260156	NCIH1373	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.6978783333275235	[501]	[223,473,469,44]	-6	hSpCas9	negative selection	8051121
272704	272727	5	+	27260156	NCIH1373	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.8830843586893788	[189]	[133,88,90,40]	-7	hSpCas9	negative selection	8051122
272746	272769	5	-	27260156	PATU8902	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.9380503425939632	[501]	[411,348,397,277]	-7	hSpCas9	negative selection	8172372
272704	272727	5	+	27260156	PATU8902	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.25324528903042287	[189]	[290,113,237,239]	-3	hSpCas9	negative selection	8172373
272746	272769	5	-	27260156	PANC1	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.9004338249966127	[501]	[249,302,157,223]	-8	hSpCas9	negative selection	8293623
272704	272727	5	+	27260156	PANC1	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.785871013166088	[189]	[79,109,118,74]	-8	hSpCas9	negative selection	8293624
272746	272769	5	-	27260156	PANC0813	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.9405804237746178	[501]	[325,285,324,293]	-8	hSpCas9	negative selection	8414874
272704	272727	5	+	27260156	PANC0813	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.5164931489453384	[189]	[116,131,240,131]	-7	hSpCas9	negative selection	8414875
272746	272769	5	-	27260156	RDES	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.19589392254631113	[501]	[375,423,589,676]	-3	hSpCas9	negative selection	8536125
272704	272727	5	+	27260156	RDES	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.3162902164820516	[189]	[182,198,153,150]	-5	hSpCas9	negative selection	8536126
272746	272769	5	-	27260156	PC3	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.7653350755242585	[501]	[139,280,596,324]	-9	hSpCas9	negative selection	8657376
272704	272727	5	+	27260156	PC3	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.3268920018792023	[189]	[176,139,215,54]	-6	hSpCas9	negative selection	8657377
272746	272769	5	-	27260156	PATU8988T	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.6653463359268466	[501]	[187,267,218,566]	-8	hSpCas9	negative selection	8778627
272704	272727	5	+	27260156	PATU8988T	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.7427205886052053	[189]	[51,198,91,103]	-8	hSpCas9	negative selection	8778628
272746	272769	5	-	27260156	T47D	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.818090854241448	[501]	[313,355,315,338]	-9	hSpCas9	negative selection	8899878
272704	272727	5	+	27260156	T47D	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.7121869249410047	[189]	[144,173,100,116]	-8	hSpCas9	negative selection	8899879
272746	272769	5	-	27260156	SU8686	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.42020644304221966	[501]	[308,327,381,499]	-6	hSpCas9	negative selection	9021129
272704	272727	5	+	27260156	SU8686	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.26637934524001494	[189]	[190,98,167,173]	-4	hSpCas9	negative selection	9021130
272746	272769	5	-	27260156	SKES1	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.7977645228240307	[501]	[266,309,294,277]	-9	hSpCas9	negative selection	9142380
272704	272727	5	+	27260156	SKES1	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-1.2741513874726405	[189]	[58,122,79,55]	-9	hSpCas9	negative selection	9142381
272746	272769	5	-	27260156	TOV112D	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.38224963762734393	[501]	[368,573,501,148]	-6	hSpCas9	negative selection	9263631
272704	272727	5	+	27260156	TOV112D	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.6532379302773665	[189]	[101,112,135,128]	-8	hSpCas9	negative selection	9263632
272746	272769	5	-	27260156	TC71	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-0.33407091826950747	[501]	[342,407,458,502]	-7	hSpCas9	negative selection	9384882
272704	272727	5	+	27260156	TC71	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.2144742593368012	[189]	[148,142,141,275]	-5	hSpCas9	negative selection	9384883
272746	272769	5	-	27260156	TC32	viability	GGAGAGAGCTTGCTGAAGCTCGG	PDCD6	ENSG00000249915	-1.0378475483043856	[501]	[230,168,284,253]	-9	hSpCas9	negative selection	9506133
272704	272727	5	+	27260156	TC32	viability	GTTATAGGGTCGATAAAGACAGG	PDCD6	ENSG00000249915	-0.8225257413119338	[189]	[138,85,100,69]	-9	hSpCas9	negative selection	9506134
271725	271748	5	-	28162770	P31FUJ	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-1.6227487227303918	[227]	[86]	-7	hSpCas9	negative selection	10208574
271800	271823	5	+	28162770	P31FUJ	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.23140813684616757	[821]	[1133]	2	hSpCas9	negative selection	10208575
271725	271748	5	-	28162770	TF1	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10377940
271800	271823	5	+	28162770	TF1	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	NaN	[NaN]	[526]	1	hSpCas9	negative selection	10377941
271725	271748	5	-	28162770	SKM1	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-1.7813597135246597	[69]	[35]	-8	hSpCas9	negative selection	10547306
271800	271823	5	+	28162770	SKM1	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	-0.8105969347497559	[251]	[253]	-6	hSpCas9	negative selection	10547307
271725	271748	5	-	28162770	SKM1	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-1.7813597135246597	[69]	[35]	-8	hSpCas9	negative selection	10716672
271800	271823	5	+	28162770	SKM1	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	-0.8105969347497559	[251]	[253]	-6	hSpCas9	negative selection	10716673
271725	271748	5	-	28162770	PL21	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-1.3786443113027118	[232]	[38]	-7	hSpCas9	negative selection	10886038
271800	271823	5	+	28162770	PL21	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	-0.19748535250271737	[850]	[322]	-1	hSpCas9	negative selection	10886039
271725	271748	5	-	28162770	P31FUJ	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-1.6227487227303918	[227]	[86]	-7	hSpCas9	negative selection	11055404
271800	271823	5	+	28162770	P31FUJ	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.23140813684616757	[821]	[1133]	2	hSpCas9	negative selection	11055405
271725	271748	5	-	28162770	OCIAML5	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-1.890105931883171	[268]	[130]	-7	hSpCas9	negative selection	11224770
271800	271823	5	+	28162770	OCIAML5	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.21851410858161602	[358]	[753]	1	hSpCas9	negative selection	11224771
271725	271748	5	-	28162770	EOL1	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-1.33986786466162	[417]	[86]	-7	hSpCas9	negative selection	11394136
271800	271823	5	+	28162770	EOL1	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.13764244832489236	[1400]	[811]	1	hSpCas9	negative selection	11394137
271725	271748	5	-	28162770	MOLM13	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-2.2272560369270002	[271]	[41]	-7	hSpCas9	negative selection	11563502
271800	271823	5	+	28162770	MOLM13	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.3993022962871664	[1119]	[1067]	3	hSpCas9	negative selection	11563503
271725	271748	5	-	28162770	HEL	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-0.8541989209235751	[301]	[106]	-5	hSpCas9	negative selection	11732868
271800	271823	5	+	28162770	HEL	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.7340068895676706	[979]	[1043]	6	hSpCas9	negative selection	11732869
271725	271748	5	-	28162770	MV411	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-1.8006567374182696	[243]	[58]	-8	hSpCas9	negative selection	11902234
271800	271823	5	+	28162770	MV411	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	-0.12462866320577204	[870]	[672]	-1	hSpCas9	negative selection	11902235
271725	271748	5	-	28162770	MONOMAC1	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-3.686421687798479	[145]	[12]	-9	hSpCas9	negative selection	12071600
271800	271823	5	+	28162770	MONOMAC1	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.08463855648705376	[486]	[591]	0	hSpCas9	negative selection	12071601
271725	271748	5	-	28162770	OCIAML2	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-1.7103002380104448	[48]	[82]	-7	hSpCas9	negative selection	12240966
271800	271823	5	+	28162770	OCIAML2	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	0.6053880416026161	[133]	[1129]	6	hSpCas9	negative selection	12240967
271725	271748	5	-	28162770	OCIAML3	viability	GCCGGGGCGGTAAGAGTAGGCGG	PDCD6	ENSG00000249915	-1.4273577709147118	[48]	[54]	-7	hSpCas9	negative selection	12410332
271800	271823	5	+	28162770	OCIAML3	viability	TCCTGTGGAACGTTTTCCAGAGG	PDCD6	ENSG00000249915	-1.0425976993140338	[231]	[339]	-6	hSpCas9	negative selection	12410333