Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 29941
• Symbol: PKN3
• Description: protein kinase N3

DataSource: http://genomecrispr.dkfz.de/#!/results/PKN3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
128705362	128705385	9	+	26472758	Jiyoye	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	-0.1894689242629182	[123]	[81]	-1	hSpCas9	negative selection	121375
128713557	128713580	9	-	26472758	Jiyoye	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-0.5152880180231062	[162]	[85]	-4	hSpCas9	negative selection	121376
128715196	128715219	9	-	26472758	Jiyoye	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	1.150399966143762	[45]	[76]	7	hSpCas9	negative selection	121377
128702905	128702928	9	+	26472758	Jiyoye	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.4168255515395927	[148]	[149]	3	hSpCas9	negative selection	121378
128705416	128705439	9	-	26472758	Jiyoye	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-0.02416393010207102	[88]	[65]	0	hSpCas9	negative selection	121379
128705782	128705805	9	+	26472758	Jiyoye	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	0.5081042903566543	[68]	[73]	4	hSpCas9	negative selection	121380
128706745	128706768	9	+	26472758	Jiyoye	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	1.3052957674866597	[43]	[81]	7	hSpCas9	negative selection	121381
128706781	128706804	9	+	26472758	Jiyoye	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	-0.9464615731088271	[45]	[17]	-6	hSpCas9	negative selection	121382
128707263	128707286	9	-	26472758	Jiyoye	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	0.5877476271476945	[14]	[16]	4	hSpCas9	negative selection	121383
128713139	128713162	9	-	26472758	Jiyoye	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	0.2678598059696041	[238]	[216]	2	hSpCas9	negative selection	121384
128705362	128705385	9	+	26472758	KBM7	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	0.519181137253858	[282,272]	[170,202]	5	hSpCas9	negative selection	312493
128713557	128713580	9	-	26472758	KBM7	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-0.44363304840343265	[673,673]	[287,185]	-4	hSpCas9	negative selection	312494
128715196	128715219	9	-	26472758	KBM7	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	0.4069574055125257	[249,248]	[188,126]	4	hSpCas9	negative selection	312495
128702905	128702928	9	+	26472758	KBM7	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.003812121679932501	[709,511]	[271,295]	0	hSpCas9	negative selection	312496
128705416	128705439	9	-	26472758	KBM7	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	0.45374105440595325	[184,131]	[141,63]	5	hSpCas9	negative selection	312497
128705782	128705805	9	+	26472758	KBM7	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	0.8159452653824146	[112,136]	[142,70]	8	hSpCas9	negative selection	312498
128706745	128706768	9	+	26472758	KBM7	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	0.32519922161260406	[209,220]	[195,66]	3	hSpCas9	negative selection	312499
128706781	128706804	9	+	26472758	KBM7	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	0.039857205157864506	[158,137]	[78,64]	0	hSpCas9	negative selection	312500
128707263	128707286	9	-	26472758	KBM7	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-0.20933726055596247	[141,117]	[87,20]	-2	hSpCas9	negative selection	312501
128713139	128713162	9	-	26472758	KBM7	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	0.558982625215541	[969,704]	[628,523]	6	hSpCas9	negative selection	312502
128705362	128705385	9	+	26472758	Raji	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	0.058473934892652846	[119]	[28]	0	hSpCas9	negative selection	503611
128713557	128713580	9	-	26472758	Raji	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-0.1871291019333624	[416]	[84]	-1	hSpCas9	negative selection	503612
128715196	128715219	9	-	26472758	Raji	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	1.0835367934192315	[121]	[59]	8	hSpCas9	negative selection	503613
128702905	128702928	9	+	26472758	Raji	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.583047393603944	[232]	[80]	5	hSpCas9	negative selection	503614
128705416	128705439	9	-	26472758	Raji	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-1.4992740364468755	[133]	[10]	-8	hSpCas9	negative selection	503615
128705782	128705805	9	+	26472758	Raji	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	0.4935661719802581	[100]	[32]	5	hSpCas9	negative selection	503616
128706745	128706768	9	+	26472758	Raji	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	-0.08091999538356748	[236]	[51]	0	hSpCas9	negative selection	503617
128706781	128706804	9	+	26472758	Raji	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	-1.365104236089144	[110]	[9]	-7	hSpCas9	negative selection	503618
128707263	128707286	9	-	26472758	Raji	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-0.9105383726236629	[80]	[9]	-6	hSpCas9	negative selection	503619
128713139	128713162	9	-	26472758	Raji	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	0.5771952571966081	[490]	[169]	5	hSpCas9	negative selection	503620
128705362	128705385	9	+	26472758	K562	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	0.306613489273791	[226]	[236]	2	hSpCas9	negative selection	694729
128713557	128713580	9	-	26472758	K562	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-2.1537449530480006	[679]	[128]	-7	hSpCas9	negative selection	694730
128715196	128715219	9	-	26472758	K562	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	0.8377934682038033	[227]	[343]	7	hSpCas9	negative selection	694731
128702905	128702928	9	+	26472758	K562	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	1.0010131285815858	[437]	[739]	8	hSpCas9	negative selection	694732
128705416	128705439	9	-	26472758	K562	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-0.4925468664997591	[204]	[122]	-3	hSpCas9	negative selection	694733
128705782	128705805	9	+	26472758	K562	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	-0.6914509349138376	[131]	[68]	-4	hSpCas9	negative selection	694734
128706745	128706768	9	+	26472758	K562	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	-0.4457260097467657	[191]	[118]	-3	hSpCas9	negative selection	694735
128706781	128706804	9	+	26472758	K562	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	0.9362964323041152	[64]	[104]	7	hSpCas9	negative selection	694736
128707263	128707286	9	-	26472758	K562	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-5.732861195833468	[62]	[0]	-9	hSpCas9	negative selection	694737
128713139	128713162	9	-	26472758	K562	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	0.16705017227812946	[631]	[598]	1	hSpCas9	negative selection	694738
128705332	128705355	9	+	26627737	DLD1	viability	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	0.4314709978569383	[382]	[35,273,176]	4	hSpCas9	negative selection	841516
128705753	128705776	9	-	26627737	DLD1	viability	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	-1.5346727973530019	[379]	[110,9,5]	-8	hSpCas9	negative selection	841517
128706748	128706771	9	+	26627737	DLD1	viability	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	1.138885489220685	[51]	[51,20,33]	9	hSpCas9	negative selection	841518
128706990	128707013	9	+	26627737	DLD1	viability	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.5627082549591913	[719]	[309,446,256]	5	hSpCas9	negative selection	841519
128707391	128707414	9	-	26627737	DLD1	viability	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.2576648514874154	[602]	[297,191,189]	2	hSpCas9	negative selection	841520
128713159	128713182	9	+	26627737	DLD1	viability	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	-0.16089346462553566	[968]	[275,209,316]	-2	hSpCas9	negative selection	841521
128705332	128705355	9	+	26627737	GBM cells	viability after 5 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	0.40338645774647386	[85]	[43,77]	6	hSpCas9	negative selection	923831
128705753	128705776	9	-	26627737	GBM cells	viability after 5 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.30490623456152255	[119]	[77,80]	5	hSpCas9	negative selection	923832
128706748	128706771	9	+	26627737	GBM cells	viability after 5 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	0.5769857799983233	[4]	[2,4]	8	hSpCas9	negative selection	923833
128706990	128707013	9	+	26627737	GBM cells	viability after 5 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	-0.09096190784060702	[283]	[147,137]	-1	hSpCas9	negative selection	923834
128707391	128707414	9	-	26627737	GBM cells	viability after 5 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	-0.4079748205375355	[333]	[184,84]	-6	hSpCas9	negative selection	923835
128713159	128713182	9	+	26627737	GBM cells	viability after 5 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	0.03835706382479864	[472]	[272,247]	0	hSpCas9	negative selection	923836
128705332	128705355	9	+	26627737	GBM cells	viability after 13 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	0.9128570499368004	[85]	[67,103]	9	hSpCas9	negative selection	1006146
128705753	128705776	9	-	26627737	GBM cells	viability after 13 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.1125050807200576	[119]	[92,51]	1	hSpCas9	negative selection	1006147
128706748	128706771	9	+	26627737	GBM cells	viability after 13 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	1.4571306462418843	[4]	[7,6]	9	hSpCas9	negative selection	1006148
128706990	128707013	9	+	26627737	GBM cells	viability after 13 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	-0.02846669150956027	[283]	[176,129]	0	hSpCas9	negative selection	1006149
128707391	128707414	9	-	26627737	GBM cells	viability after 13 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	-0.3406916552246919	[333]	[141,143]	-4	hSpCas9	negative selection	1006150
128713159	128713182	9	+	26627737	GBM cells	viability after 13 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	0.5279602229616235	[472]	[315,413]	6	hSpCas9	negative selection	1006151
128705332	128705355	9	+	26627737	GBM cells	viability after 21 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	0.701896058357146	[85]	[75,75]	7	hSpCas9	negative selection	1088461
128705753	128705776	9	-	26627737	GBM cells	viability after 21 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	-0.08884212718944084	[119]	[65,56]	-1	hSpCas9	negative selection	1088462
128706748	128706771	9	+	26627737	GBM cells	viability after 21 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	1.761680399894372	[4]	[15,2]	9	hSpCas9	negative selection	1088463
128706990	128707013	9	+	26627737	GBM cells	viability after 21 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.21975435985614689	[283]	[198,161]	2	hSpCas9	negative selection	1088464
128707391	128707414	9	-	26627737	GBM cells	viability after 21 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	-0.27647017427743314	[333]	[165,134]	-3	hSpCas9	negative selection	1088465
128713159	128713182	9	+	26627737	GBM cells	viability after 21 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	0.43651277342429495	[472]	[364,331]	4	hSpCas9	negative selection	1088466
128705332	128705355	9	+	26627737	RPE1	viability after 9 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	0.7259690212484456	[344]	[158,203]	5	hSpCas9	negative selection	1170776
128705753	128705776	9	-	26627737	RPE1	viability after 9 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.6903016500420555	[263]	[128,138]	4	hSpCas9	negative selection	1170777
128706748	128706771	9	+	26627737	RPE1	viability after 9 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	-0.49575369885618037	[270]	[50,71]	-4	hSpCas9	negative selection	1170778
128706990	128707013	9	+	26627737	RPE1	viability after 9 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.3857180688121329	[1658]	[592,788]	2	hSpCas9	negative selection	1170779
128707391	128707414	9	-	26627737	RPE1	viability after 9 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	-0.5733460007524462	[1168]	[224,272]	-4	hSpCas9	negative selection	1170780
128713159	128713182	9	+	26627737	RPE1	viability after 9 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	-0.7278617390367419	[2625]	[505,483]	-5	hSpCas9	negative selection	1170781
128705332	128705355	9	+	26627737	RPE1	viability after 12 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	1.0681191337704818	[344]	[205,181]	6	hSpCas9	negative selection	1253091
128705753	128705776	9	-	26627737	RPE1	viability after 12 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.8571814440387339	[263]	[110,146]	5	hSpCas9	negative selection	1253092
128706748	128706771	9	+	26627737	RPE1	viability after 12 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	-0.2212429609537956	[270]	[60,63]	-1	hSpCas9	negative selection	1253093
128706990	128707013	9	+	26627737	RPE1	viability after 12 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.4363008386049856	[1658]	[487,724]	3	hSpCas9	negative selection	1253094
128707391	128707414	9	-	26627737	RPE1	viability after 12 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	-0.5864058106067906	[1168]	[197,220]	-4	hSpCas9	negative selection	1253095
128713159	128713182	9	+	26627737	RPE1	viability after 12 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	-0.6624719200403941	[2625]	[504,382]	-4	hSpCas9	negative selection	1253096
128705332	128705355	9	+	26627737	RPE1	viability after 15 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-0.01124935357491541	[344]	[77,114]	0	hSpCas9	negative selection	1335406
128705753	128705776	9	-	26627737	RPE1	viability after 15 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.607665609941885	[263]	[68,156]	4	hSpCas9	negative selection	1335407
128706748	128706771	9	+	26627737	RPE1	viability after 15 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	-0.22036464672841993	[270]	[76,54]	-1	hSpCas9	negative selection	1335408
128706990	128707013	9	+	26627737	RPE1	viability after 15 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.0386145272131011	[1658]	[339,618]	0	hSpCas9	negative selection	1335409
128707391	128707414	9	-	26627737	RPE1	viability after 15 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	-0.42389298741278725	[1168]	[302,191]	-3	hSpCas9	negative selection	1335410
128713159	128713182	9	+	26627737	RPE1	viability after 15 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	-0.8618473701738526	[2625]	[394,421]	-5	hSpCas9	negative selection	1335411
128705332	128705355	9	+	26627737	RPE1	viability after 18 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	1.2349390966264222	[344]	[164,276]	7	hSpCas9	negative selection	1417721
128705753	128705776	9	-	26627737	RPE1	viability after 18 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.6319695922338003	[263]	[63,159]	4	hSpCas9	negative selection	1417722
128706748	128706771	9	+	26627737	RPE1	viability after 18 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	-0.4564556384195104	[270]	[61,43]	-3	hSpCas9	negative selection	1417723
128706990	128707013	9	+	26627737	RPE1	viability after 18 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.15877991640295286	[1658]	[493,505]	1	hSpCas9	negative selection	1417724
128707391	128707414	9	-	26627737	RPE1	viability after 18 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	-0.17994336769445668	[1168]	[277,278]	-1	hSpCas9	negative selection	1417725
128713159	128713182	9	+	26627737	RPE1	viability after 18 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	-0.7751161767772944	[2625]	[358,472]	-5	hSpCas9	negative selection	1417726
128705332	128705355	9	+	26627737	HeLa	viability after 8 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-0.837912562682797	[315]	[6,184,26]	-7	hSpCas9	negative selection	1500036
128705753	128705776	9	-	26627737	HeLa	viability after 8 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.10869397038306583	[225]	[67,109,129]	1	hSpCas9	negative selection	1500037
128706748	128706771	9	+	26627737	HeLa	viability after 8 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	0.6698435067972289	[399]	[278,257,292]	6	hSpCas9	negative selection	1500038
128706990	128707013	9	+	26627737	HeLa	viability after 8 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.49584134083218767	[617]	[324,440,360]	4	hSpCas9	negative selection	1500039
128707391	128707414	9	-	26627737	HeLa	viability after 8 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.26237425616910093	[533]	[493,295,105]	2	hSpCas9	negative selection	1500040
128713159	128713182	9	+	26627737	HeLa	viability after 8 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	-0.10593100300393085	[475]	[254,22,304]	-1	hSpCas9	negative selection	1500041
128705332	128705355	9	+	26627737	HeLa	viability after 12 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-0.3027428068101666	[315]	[183,0,145]	-3	hSpCas9	negative selection	1582351
128705753	128705776	9	-	26627737	HeLa	viability after 12 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	-0.01556401456866241	[225]	[104,40,136]	0	hSpCas9	negative selection	1582352
128706748	128706771	9	+	26627737	HeLa	viability after 12 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	0.5981416062573813	[399]	[495,144,127]	5	hSpCas9	negative selection	1582353
128706990	128707013	9	+	26627737	HeLa	viability after 12 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	-0.1710524733875496	[617]	[246,142,299]	-1	hSpCas9	negative selection	1582354
128707391	128707414	9	-	26627737	HeLa	viability after 12 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.33529125529183956	[533]	[395,265,177]	3	hSpCas9	negative selection	1582355
128713159	128713182	9	+	26627737	HeLa	viability after 12 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	0.4274034541515514	[475]	[156,240,394]	3	hSpCas9	negative selection	1582356
128705332	128705355	9	+	26627737	HeLa	viability after 15 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-1.8646309700987227	[315]	[61,27,13]	-9	hSpCas9	negative selection	1664666
128705753	128705776	9	-	26627737	HeLa	viability after 15 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.37632936543665896	[225]	[65,148,145]	3	hSpCas9	negative selection	1664667
128706748	128706771	9	+	26627737	HeLa	viability after 15 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	0.31026336897115425	[399]	[244,87,277]	2	hSpCas9	negative selection	1664668
128706990	128707013	9	+	26627737	HeLa	viability after 15 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.2615673394220258	[617]	[486,154,256]	2	hSpCas9	negative selection	1664669
128707391	128707414	9	-	26627737	HeLa	viability after 15 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.23662175314489697	[533]	[113,221,448]	2	hSpCas9	negative selection	1664670
128713159	128713182	9	+	26627737	HeLa	viability after 15 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	-0.40834962818690235	[475]	[241,154,30]	-4	hSpCas9	negative selection	1664671
128705332	128705355	9	+	26627737	HeLa	viability after 18 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-1.7583660359422182	[315]	[42,27,13]	-9	hSpCas9	negative selection	1746981
128705753	128705776	9	-	26627737	HeLa	viability after 18 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.451444968628297	[225]	[52,127,145]	4	hSpCas9	negative selection	1746982
128706748	128706771	9	+	26627737	HeLa	viability after 18 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	0.318760046791974	[399]	[168,69,277]	2	hSpCas9	negative selection	1746983
128706990	128707013	9	+	26627737	HeLa	viability after 18 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.2673680282479767	[617]	[326,130,256]	2	hSpCas9	negative selection	1746984
128707391	128707414	9	-	26627737	HeLa	viability after 18 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.23155229793200516	[533]	[72,185,448]	2	hSpCas9	negative selection	1746985
128713159	128713182	9	+	26627737	HeLa	viability after 18 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	-0.4373356707911592	[475]	[152,132,30]	-4	hSpCas9	negative selection	1746986
128705332	128705355	9	+	26627737	HCT116	viability after 6 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-1.8844892521479673	[622]	[70,1]	-8	hSpCas9	negative selection	1829296
128705753	128705776	9	-	26627737	HCT116	viability after 6 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	-2.227566219028464	[653]	[39,11]	-8	hSpCas9	negative selection	1829297
128706748	128706771	9	+	26627737	HCT116	viability after 6 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	-1.8873239462129636	[1038]	[67,30]	-8	hSpCas9	negative selection	1829298
128706990	128707013	9	+	26627737	HCT116	viability after 6 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	1.2657090258394113	[968]	[422,334]	6	hSpCas9	negative selection	1829299
128707391	128707414	9	-	26627737	HCT116	viability after 6 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.39357952426284715	[481]	[192,47]	2	hSpCas9	negative selection	1829300
128713159	128713182	9	+	26627737	HCT116	viability after 6 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	0.6449885728730479	[868]	[328,149]	3	hSpCas9	negative selection	1829301
128705332	128705355	9	+	26627737	HCT116	viability after 8 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-1.4144878932689162	[293]	[89,44,47]	-9	hSpCas9	negative selection	1911611
128705753	128705776	9	-	26627737	HCT116	viability after 8 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.5791354102403221	[116]	[49,131,105]	6	hSpCas9	negative selection	1911612
128706748	128706771	9	+	26627737	HCT116	viability after 8 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	0.30196963695389506	[411]	[327,273,238]	3	hSpCas9	negative selection	1911613
128706990	128707013	9	+	26627737	HCT116	viability after 8 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	-0.02106460080562611	[623]	[371,292,351]	0	hSpCas9	negative selection	1911614
128707391	128707414	9	-	26627737	HCT116	viability after 8 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	-0.2533228149312083	[404]	[231,185,144]	-3	hSpCas9	negative selection	1911615
128713159	128713182	9	+	26627737	HCT116	viability after 8 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	1.7014963829441643	[275]	[502,399,579]	9	hSpCas9	negative selection	1911616
128705332	128705355	9	+	26627737	HCT116	viability after 9 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-0.3928976372297432	[622]	[162,97]	-3	hSpCas9	negative selection	1993926
128705753	128705776	9	-	26627737	HCT116	viability after 9 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	-1.7655735943616586	[653]	[66,38]	-8	hSpCas9	negative selection	1993927
128706748	128706771	9	+	26627737	HCT116	viability after 9 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	-4.252194511149055	[1038]	[13,14]	-9	hSpCas9	negative selection	1993928
128706990	128707013	9	+	26627737	HCT116	viability after 9 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.133605861031437	[968]	[394,195]	1	hSpCas9	negative selection	1993929
128707391	128707414	9	-	26627737	HCT116	viability after 9 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	1.2322256785972536	[481]	[131,436]	7	hSpCas9	negative selection	1993930
128713159	128713182	9	+	26627737	HCT116	viability after 9 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	0.6289656583024373	[868]	[636,138]	4	hSpCas9	negative selection	1993931
128705332	128705355	9	+	26627737	HCT116	viability after 12 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-1.1949775126344304	[293]	[68,53,78]	-8	hSpCas9	negative selection	2076241
128705753	128705776	9	-	26627737	HCT116	viability after 12 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.6410463819789473	[116]	[51,115,123]	6	hSpCas9	negative selection	2076242
128706748	128706771	9	+	26627737	HCT116	viability after 12 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	0.10436988430716049	[411]	[281,151,257]	1	hSpCas9	negative selection	2076243
128706990	128707013	9	+	26627737	HCT116	viability after 12 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	-0.1345644654212249	[623]	[397,279,208]	-1	hSpCas9	negative selection	2076244
128707391	128707414	9	-	26627737	HCT116	viability after 12 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.40543475790174066	[404]	[318,345,178]	4	hSpCas9	negative selection	2076245
128713159	128713182	9	+	26627737	HCT116	viability after 12 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	1.4722820012047098	[275]	[470,265,460]	9	hSpCas9	negative selection	2076246
128705332	128705355	9	+	26627737	HCT116	viability after 15 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-1.6499579093742047	[293]	[52,28,78]	-9	hSpCas9	negative selection	2158556
128705753	128705776	9	-	26627737	HCT116	viability after 15 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	1.2094231343509527	[116]	[150,191,122]	8	hSpCas9	negative selection	2158557
128706748	128706771	9	+	26627737	HCT116	viability after 15 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	0.12757983910947374	[411]	[174,223,364]	1	hSpCas9	negative selection	2158558
128706990	128707013	9	+	26627737	HCT116	viability after 15 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.26379973156823455	[623]	[790,388,157]	2	hSpCas9	negative selection	2158559
128707391	128707414	9	-	26627737	HCT116	viability after 15 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.31852388529527387	[404]	[393,297,191]	3	hSpCas9	negative selection	2158560
128713159	128713182	9	+	26627737	HCT116	viability after 15 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	1.6090210527042226	[275]	[738,372,370]	9	hSpCas9	negative selection	2158561
128705332	128705355	9	+	26627737	HCT116	viability after 18 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-1.364523689866337	[293]	[6,62,96]	-8	hSpCas9	negative selection	2240871
128705753	128705776	9	-	26627737	HCT116	viability after 18 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.7753326113697279	[116]	[109,137,36]	6	hSpCas9	negative selection	2240872
128706748	128706771	9	+	26627737	HCT116	viability after 18 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	0.45038760695322816	[411]	[240,194,390]	4	hSpCas9	negative selection	2240873
128706990	128707013	9	+	26627737	HCT116	viability after 18 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.5947555545219887	[623]	[638,386,339]	5	hSpCas9	negative selection	2240874
128707391	128707414	9	-	26627737	HCT116	viability after 18 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.0383314785302194	[404]	[259,152,192]	0	hSpCas9	negative selection	2240875
128713159	128713182	9	+	26627737	HCT116	viability after 18 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	1.7901730011700363	[275]	[657,418,302]	9	hSpCas9	negative selection	2240876
128702903	128702926	9	+	24336569	HL60	viability	CCGGAGCGGCGCCATGGAGGAGG	PKN3	ENSG00000160447	0.5048562308192109	[353]	[1062]	4	hSpCas9	negative selection	2284413
128702931	128702954	9	-	24336569	HL60	viability	CCCACGCCGTTCACCTGCCGCGG	PKN3	ENSG00000160447	0.33506301679043404	[362]	[968]	3	hSpCas9	negative selection	2284414
128705298	128705321	9	+	24336569	HL60	viability	TGCAGCCTGGGCCGAGCCAGTGG	PKN3	ENSG00000160447	-0.4400402639348552	[1210]	[1888]	-4	hSpCas9	negative selection	2284415
128705323	128705346	9	-	24336569	HL60	viability	TCACCTCCTTCTCATCCTCTGGG	PKN3	ENSG00000160447	-0.16307786618254827	[199]	[377]	-1	hSpCas9	negative selection	2284416
128705331	128705354	9	+	24336569	HL60	viability	ATGAGAAGGAGGTGATCCGCCGG	PKN3	ENSG00000160447	-0.3748781332477398	[1026]	[1675]	-3	hSpCas9	negative selection	2284417
128705347	128705370	9	-	24336569	HL60	viability	GCTCTTTCTGGATGGCCCGGCGG	PKN3	ENSG00000160447	0.2421838772845931	[502]	[1258]	2	hSpCas9	negative selection	2284418
128705355	128705378	9	-	24336569	HL60	viability	GATCTTCAGCTCTTTCTGGATGG	PKN3	ENSG00000160447	0.45577535958322657	[460]	[1337]	4	hSpCas9	negative selection	2284419
128705362	128705385	9	+	24336569	HL60	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	0.7349284060525653	[340]	[1200]	6	hSpCas9	negative selection	2284420
128705386	128705409	9	+	24336569	HL60	viability	GGTGGAGAACCTGCGGCGCGTGG	PKN3	ENSG00000160447	-0.5598154107190169	[1016]	[1459]	-5	hSpCas9	negative selection	2284421
128705395	128705418	9	-	24336569	HL60	viability	GGTCTGTGGCCACGCGCCGCAGG	PKN3	ENSG00000160447	0.8157763249459028	[199]	[744]	6	hSpCas9	negative selection	2284422
128702903	128702926	9	+	24336569	KBM7	viability	CCGGAGCGGCGCCATGGAGGAGG	PKN3	ENSG00000160447	0.9316737275899878	[448]	[2335]	7	hSpCas9	negative selection	2351590
128702931	128702954	9	-	24336569	KBM7	viability	CCCACGCCGTTCACCTGCCGCGG	PKN3	ENSG00000160447	1.2493517358150712	[189]	[1231]	8	hSpCas9	negative selection	2351591
128705298	128705321	9	+	24336569	KBM7	viability	TGCAGCCTGGGCCGAGCCAGTGG	PKN3	ENSG00000160447	-0.1608586739220068	[588]	[1436]	-1	hSpCas9	negative selection	2351592
128705323	128705346	9	-	24336569	KBM7	viability	TCACCTCCTTCTCATCCTCTGGG	PKN3	ENSG00000160447	4.190494640631837	[19]	[995]	9	hSpCas9	negative selection	2351593
128705331	128705354	9	+	24336569	KBM7	viability	ATGAGAAGGAGGTGATCCGCCGG	PKN3	ENSG00000160447	0.6576174901413302	[584]	[2516]	6	hSpCas9	negative selection	2351594
128705347	128705370	9	-	24336569	KBM7	viability	GCTCTTTCTGGATGGCCCGGCGG	PKN3	ENSG00000160447	1.0458552092227253	[384]	[2167]	8	hSpCas9	negative selection	2351595
128705355	128705378	9	-	24336569	KBM7	viability	GATCTTCAGCTCTTTCTGGATGG	PKN3	ENSG00000160447	0.07620283349847223	[569]	[1638]	0	hSpCas9	negative selection	2351596
128705362	128705385	9	+	24336569	KBM7	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	0.5973415499520818	[331]	[1369]	5	hSpCas9	negative selection	2351597
128705386	128705409	9	+	24336569	KBM7	viability	GGTGGAGAACCTGCGGCGCGTGG	PKN3	ENSG00000160447	0.1064603244103795	[502]	[1476]	1	hSpCas9	negative selection	2351598
128705395	128705418	9	-	24336569	KBM7	viability	GGTCTGTGGCCACGCGCCGCAGG	PKN3	ENSG00000160447	-0.0871769538468844	[258]	[664]	0	hSpCas9	negative selection	2351599
128713190	128713213	9	+	27013184	SW480	treatment with recombinant TRAIL	AGCTTGCCAGTGAGTAGGGAAGG	PKN3	ENSG00000160447	-0.05360197957272528	[417,423]	[150,208]	0	hSpCas9	positive selection	2962622
128713297	128713320	9	+	27013184	SW480	treatment with recombinant TRAIL	AAAGGTGGACAACCGTGTTGTGG	PKN3	ENSG00000160447	-1.3954443137747807	[87,181]	[25,14]	-6	hSpCas9	positive selection	2962623
128713298	128713321	9	+	27013184	SW480	treatment with recombinant TRAIL	AAGGTGGACAACCGTGTTGTGGG	PKN3	ENSG00000160447	0.7949817679324432	[136,327]	[130,219]	4	hSpCas9	positive selection	2962624
128713299	128713322	9	+	27013184	SW480	treatment with recombinant TRAIL	AGGTGGACAACCGTGTTGTGGGG	PKN3	ENSG00000160447	0.7883421931085235	[420,529]	[214,543]	4	hSpCas9	positive selection	2962625
128714584	128714607	9	-	27013184	SW480	treatment with recombinant TRAIL	GGTGTCATCTCTTCACCCAAGGG	PKN3	ENSG00000160447	1.5531085257524566	[175,207]	[93,450]	7	hSpCas9	positive selection	2962626
128714585	128714608	9	-	27013184	SW480	treatment with recombinant TRAIL	GGGTGTCATCTCTTCACCCAAGG	PKN3	ENSG00000160447	-0.13517900798612598	[371,275]	[109,155]	0	hSpCas9	positive selection	2962627
128714619	128714642	9	-	27013184	SW480	treatment with recombinant TRAIL	CCTGGGGGAGGTAGAGGCGTGGG	PKN3	ENSG00000160447	-2.690704150556185	[23,36]	[1,1]	-8	hSpCas9	positive selection	2962628
128714644	128714667	9	-	27013184	SW480	treatment with recombinant TRAIL	ACCGGAGTCTCCTCGGATGTTGG	PKN3	ENSG00000160447	-0.170663366907692	[274,244]	[67,145]	0	hSpCas9	positive selection	2962629
128713335	128713358	9	+	27013184	SW480	treatment with recombinant TRAIL	GGCAGGTGGCCGAACAGTCCTGG	PKN3	ENSG00000160447	-0.5706489104945656	[269,271]	[48,120]	-3	hSpCas9	positive selection	2962630
128713336	128713359	9	+	27013184	SW480	treatment with recombinant TRAIL	GCAGGTGGCCGAACAGTCCTGGG	PKN3	ENSG00000160447	-1.2438767441925371	[332,308]	[16,117]	-5	hSpCas9	positive selection	2962631
128713360	128713383	9	+	27013184	SW480	treatment with recombinant TRAIL	CCAGACCTTTGTCATCCCACTGG	PKN3	ENSG00000160447	1.2666628499291963	[493,807]	[646,681]	6	hSpCas9	positive selection	2962632
128713371	128713394	9	+	27013184	SW480	treatment with recombinant TRAIL	TCATCCCACTGGAGCGAGTAAGG	PKN3	ENSG00000160447	0.9059022397244134	[339,294]	[318,171]	4	hSpCas9	positive selection	2962633
128713375	128713398	9	+	27013184	SW480	treatment with recombinant TRAIL	CCCACTGGAGCGAGTAAGGCTGG	PKN3	ENSG00000160447	5.470495380466827	[1,2]	[1,110]	9	hSpCas9	positive selection	2962634
128714619	128714642	9	+	27013184	SW480	treatment with recombinant TRAIL	CCCACGCCTCTACCTCCCCCAGG	PKN3	ENSG00000160447	-0.9620671602226653	[635,505]	[76,199]	-4	hSpCas9	positive selection	2962635
128714648	128714671	9	+	27013184	SW480	treatment with recombinant TRAIL	CATCCGAGGAGACTCCGGTGAGG	PKN3	ENSG00000160447	-0.05702634892477146	[261,141]	[111,48]	0	hSpCas9	positive selection	2962636
128714649	128714672	9	+	27013184	SW480	treatment with recombinant TRAIL	ATCCGAGGAGACTCCGGTGAGGG	PKN3	ENSG00000160447	-1.126754884039645	[86,242]	[29,32]	-5	hSpCas9	positive selection	2962637
128714650	128714673	9	+	27013184	SW480	treatment with recombinant TRAIL	TCCGAGGAGACTCCGGTGAGGGG	PKN3	ENSG00000160447	2.436846437464446	[256,318]	[578,790]	9	hSpCas9	positive selection	2962638
128714654	128714677	9	+	27013184	SW480	treatment with recombinant TRAIL	AGGAGACTCCGGTGAGGGGCTGG	PKN3	ENSG00000160447	-0.27694878567443865	[152,188]	[68,47]	-1	hSpCas9	positive selection	2962639
128714657	128714680	9	+	27013184	SW480	treatment with recombinant TRAIL	AGACTCCGGTGAGGGGCTGGAGG	PKN3	ENSG00000160447	-1.6693627738368657	[426,517]	[25,116]	-6	hSpCas9	positive selection	2962640
128714658	128714681	9	+	27013184	SW480	treatment with recombinant TRAIL	GACTCCGGTGAGGGGCTGGAGGG	PKN3	ENSG00000160447	-2.126675963234305	[47,168]	[3,18]	-7	hSpCas9	positive selection	2962641
128713143	128713166	9	+	27013184	SW480	treatment with recombinant TRAIL	CGAGGGCTGGCTTCGGACCAAGG	PKN3	ENSG00000160447	-3.423721138827425	[461,711]	[30,11]	-9	hSpCas9	positive selection	2962642
128713185	128713208	9	+	27013184	SW480	treatment with recombinant TRAIL	AGGCGAGCTTGCCAGTGAGTAGG	PKN3	ENSG00000160447	1.8597634013663515	[15,32]	[4,82]	8	hSpCas9	positive selection	2962643
128713186	128713209	9	+	27013184	SW480	treatment with recombinant TRAIL	GGCGAGCTTGCCAGTGAGTAGGG	PKN3	ENSG00000160447	-1.755873808027851	[387,454]	[24,93]	-7	hSpCas9	positive selection	2962644
128713142	128713165	9	-	27013184	SW480	treatment with recombinant TRAIL	CTTGGTCCGAAGCCAGCCCTCGG	PKN3	ENSG00000160447	-0.2914689500572567	[822,1093]	[251,449]	-1	hSpCas9	positive selection	2962645
128713173	128713196	9	-	27013184	SW480	treatment with recombinant TRAIL	CAAGCTCGCCTCGGCCACGCTGG	PKN3	ENSG00000160447	3.616331810973463	[135,107]	[735,532]	9	hSpCas9	positive selection	2962646
128713182	128713205	9	-	27013184	SW480	treatment with recombinant TRAIL	ACTCACTGGCAAGCTCGCCTCGG	PKN3	ENSG00000160447	0.29250910995776896	[219,270]	[64,218]	1	hSpCas9	positive selection	2962647
128713196	128713219	9	-	27013184	SW480	treatment with recombinant TRAIL	GAAGCTCCTTCCCTACTCACTGG	PKN3	ENSG00000160447	-0.18221201929427	[5474,3908]	[1136,2769]	-1	hSpCas9	positive selection	2962648
128713365	128713388	9	-	27013184	SW480	treatment with recombinant TRAIL	TCGCTCCAGTGGGATGACAAAGG	PKN3	ENSG00000160447	-0.38285305741933257	[294,505]	[88,186]	-2	hSpCas9	positive selection	2962649
128713375	128713398	9	-	27013184	SW480	treatment with recombinant TRAIL	CCAGCCTTACTCGCTCCAGTGGG	PKN3	ENSG00000160447	0.6848542981621215	[164,401]	[209,159]	3	hSpCas9	positive selection	2962650
128713376	128713399	9	-	27013184	SW480	treatment with recombinant TRAIL	GCCAGCCTTACTCGCTCCAGTGG	PKN3	ENSG00000160447	-4.242725637062844	[406,497]	[15,1]	-9	hSpCas9	positive selection	2962651
128713375	128713398	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGCCTTACTCGCTCCAGTGGG	PKN3	ENSG00000160447	0.11651304739407678	[4,3]	[3,3]	2	hSpCas9	positive selection	3011609
128705416	128705439	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-1.4245990877976369	[2,2]	[0,0]	-9	hSpCas9	positive selection	3011610
128714057	128714080	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	0.2178404362698192	[4,5]	[4,5]	4	hSpCas9	positive selection	3011611
128713605	128713628	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCCTCAGCCTGGTACCGCAGGG	PKN3	ENSG00000160447	-0.5841801428233295	[2,2]	[2,0]	-7	hSpCas9	positive selection	3011612
128713375	128713398	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGCCTTACTCGCTCCAGTGGG	PKN3	ENSG00000160447	0.21945259180852736	[4,4]	[3,3]	4	hSpCas9	positive selection	3079467
128705416	128705439	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-0.29623042586447	[2,2]	[1,0]	-4	hSpCas9	positive selection	3079468
128714057	128714080	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	-0.17505379032039003	[4,4]	[4,1]	-3	hSpCas9	positive selection	3079469
128713605	128713628	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCCTCAGCCTGGTACCGCAGGG	PKN3	ENSG00000160447	0.13295454704315607	[2,2]	[3,0]	2	hSpCas9	positive selection	3079470
128706921	128706944		+	24336571	A375	resistance to PLX after 7 days	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.00766508521669329	[17,17]	[15,18]	0	hSpCas9	positive selection	3135879
128702914	128702937		-	24336571	A375	resistance to PLX after 7 days	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	0.4650048270621955	[5,5]	[7,8]	9	hSpCas9	positive selection	3135880
128706981	128707004		+	24336571	A375	resistance to PLX after 7 days	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.22984028496973208	[1,1]	[1,1]	-7	hSpCas9	positive selection	3135881
128702905	128702928		+	24336571	A375	resistance to PLX after 7 days	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.012392902759575053	[5,4]	[4,4]	0	hSpCas9	positive selection	3135882
128706921	128706944		+	24336571	A375	resistance to PLX after 14 days	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.5608797161329621	[11,18]	[4,3]	-6	hSpCas9	positive selection	3193672
128702914	128702937		-	24336571	A375	resistance to PLX after 14 days	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	0.9356397798647813	[5,3]	[3,3]	7	hSpCas9	positive selection	3193673
128706981	128707004		+	24336571	A375	resistance to PLX after 14 days	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	0.5964810439130803	[2,1]	[1,1]	5	hSpCas9	positive selection	3193674
128702905	128702928		+	24336571	A375	resistance to PLX after 14 days	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	2.0035624049316474	[4,3]	[8,6]	9	hSpCas9	positive selection	3193675
128706921	128706944		+	24336571	A375	viability after 7 days	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.06697135982805247	[19]	[17,17]	-1	hSpCas9	negative selection	3251465
128702914	128702937		-	24336571	A375	viability after 7 days	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.9361957076383949	[11]	[5,5]	-8	hSpCas9	negative selection	3251466
128706981	128707004		+	24336571	A375	viability after 7 days	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.27365976141306136	[2]	[1,1]	-4	hSpCas9	negative selection	3251467
128702905	128702928		+	24336571	A375	viability after 7 days	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.40022419613382965	[7]	[5,4]	-5	hSpCas9	negative selection	3251468
128706921	128706944		+	24336571	A375	viability after 14 days	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.2553204330143465	[19]	[11,18]	-3	hSpCas9	negative selection	3309258
128702914	128702937		-	24336571	A375	viability after 14 days	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-1.19072388624576	[11]	[5,3]	-9	hSpCas9	negative selection	3309259
128706981	128707004		+	24336571	A375	viability after 14 days	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.1409328112832342	[2]	[2,1]	-2	hSpCas9	negative selection	3309260
128702905	128702928		+	24336571	A375	viability after 14 days	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.6983121513199547	[7]	[4,3]	-7	hSpCas9	negative selection	3309261
128707394	128707417	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.7654731151161606	[89,89]	[0,0]	4	hSpCas9	positive selection	3386067
128702905	128702928	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	3.4499712893882313	[13,13]	[0,0]	9	hSpCas9	positive selection	3386068
128702914	128702937	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	0.8997742068277513	[81,81]	[0,0]	4	hSpCas9	positive selection	3386069
128713375	128713398	9	-	26780180	HT29	viability (Avana library 4 designs)	CCAGCCTTACTCGCTCCAGTGGG	PKN3	ENSG00000160447	1.30441366424441	[]	[]	5	hSpCas9	negative selection	3449700
128705416	128705439	9	-	26780180	HT29	viability (Avana library 4 designs)	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	1.63114251828325	[]	[]	6	hSpCas9	negative selection	3449701
128714056	128714079	9	+	26780180	HT29	viability (Avana library 4 designs)	GCGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	1.10757817971721	[]	[]	4	hSpCas9	negative selection	3449702
128713604	128713627	9	+	26780180	HT29	viability (Avana library 4 designs)	TCCCTCAGCCTGGTACCGCAGGG	PKN3	ENSG00000160447	2.02967891446291	[]	[]	7	hSpCas9	negative selection	3449703
128705416	128705439	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	1.8581799181244	[]	[]	2	hSpCas9	negative selection	3544586
128714056	128714079	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	2.51237112494284	[]	[]	4	hSpCas9	negative selection	3544587
128713375	128713398	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGCCTTACTCGCTCCAGTGGG	PKN3	ENSG00000160447	-3.30196671999176	[]	[]	-4	hSpCas9	negative selection	3544588
128713604	128713627	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCCTCAGCCTGGTACCGCAGGG	PKN3	ENSG00000160447	-0.281788307376409	[]	[]	0	hSpCas9	negative selection	3544589
128714053	128714076	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGCGATCCTGTCATTGAGAGG	PKN3	ENSG00000160447	3.49588484618397	[]	[]	5	hSpCas9	negative selection	3544590
128705347	128705370	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCTTTCTGGATGGCCCGGCGG	PKN3	ENSG00000160447	4.82173759213823	[]	[]	7	hSpCas9	negative selection	3544591
128705416	128705439	9	-	26780180	A375	viability (Avana lentiGuide)	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	4.44409119900437	[]	[]	4	hSpCas9	negative selection	3653245
128714056	128714079	9	+	26780180	A375	viability (Avana lentiGuide)	GCGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	2.71707231396669	[]	[]	3	hSpCas9	negative selection	3653246
128713375	128713398	9	-	26780180	A375	viability (Avana lentiGuide)	CCAGCCTTACTCGCTCCAGTGGG	PKN3	ENSG00000160447	5.24267455098013	[]	[]	4	hSpCas9	negative selection	3653247
128713604	128713627	9	+	26780180	A375	viability (Avana lentiGuide)	TCCCTCAGCCTGGTACCGCAGGG	PKN3	ENSG00000160447	4.23193989676447	[]	[]	4	hSpCas9	negative selection	3653248
128714053	128714076	9	+	26780180	A375	viability (Avana lentiGuide)	TCTGCGATCCTGTCATTGAGAGG	PKN3	ENSG00000160447	5.21065285290544	[]	[]	4	hSpCas9	negative selection	3653249
128705347	128705370	9	-	26780180	A375	viability (Avana lentiGuide)	GCTCTTTCTGGATGGCCCGGCGG	PKN3	ENSG00000160447	1.72491496551408	[]	[]	2	hSpCas9	negative selection	3653250
128705416	128705439	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-0.18814537378186513	[3]	[3,3]	-3	hSpCas9	positive selection	3761904
128714056	128714079	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	-0.06615765697438943	[5]	[5,4]	-1	hSpCas9	positive selection	3761905
128713375	128713398	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGCCTTACTCGCTCCAGTGGG	PKN3	ENSG00000160447	0.021082164390553285	[4]	[4,4]	0	hSpCas9	positive selection	3761906
128713604	128713627	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCCTCAGCCTGGTACCGCAGGG	PKN3	ENSG00000160447	0.008890899674237007	[4]	[3,4]	0	hSpCas9	positive selection	3761907
128714053	128714076	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGCGATCCTGTCATTGAGAGG	PKN3	ENSG00000160447	0.1492745012427994	[5]	[5,5]	4	hSpCas9	positive selection	3761908
128705347	128705370	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCTTTCTGGATGGCCCGGCGG	PKN3	ENSG00000160447	0.17107222182556103	[5]	[6,6]	4	hSpCas9	positive selection	3761909
128705416	128705439	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-0.44942248054031525	[4]	[2,2]	-5	hSpCas9	positive selection	3870511
128714056	128714079	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	-0.17861890291418397	[7]	[6,3]	-2	hSpCas9	positive selection	3870512
128713375	128713398	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGCCTTACTCGCTCCAGTGGG	PKN3	ENSG00000160447	-0.18251829026176747	[5]	[4,3]	-3	hSpCas9	positive selection	3870513
128713604	128713627	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCCTCAGCCTGGTACCGCAGGG	PKN3	ENSG00000160447	-0.1778666285584814	[4]	[3,2]	-2	hSpCas9	positive selection	3870514
128714053	128714076	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGCGATCCTGTCATTGAGAGG	PKN3	ENSG00000160447	0.18966595534061928	[6]	[5,5]	4	hSpCas9	positive selection	3870515
128705347	128705370	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCTTTCTGGATGGCCCGGCGG	PKN3	ENSG00000160447	0.10859549083300907	[6]	[5,6]	2	hSpCas9	positive selection	3870516
128706921	128706944	9	+	26780180	A375	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	1.78227191794608	[]	[]	9	hSpCas9	negative selection	3981328
128702914	128702937	9	-	26780180	A375	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	0.966815772845281	[]	[]	4	hSpCas9	negative selection	3981329
128707394	128707417	9	-	26780180	A375	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.978003728437584	[]	[]	4	hSpCas9	negative selection	3981330
128706981	128707004	9	+	26780180	A375	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	1.39627003747906	[]	[]	7	hSpCas9	negative selection	3981331
128702905	128702928	9	+	26780180	A375	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.42527386082678	[]	[]	1	hSpCas9	negative selection	3981332
128707384	128707407	9	+	26780180	A375	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.11475838673746	[]	[]	0	hSpCas9	negative selection	3981333
128706921	128706944	9	+	26780180	HT29	viability (GeCKOv2 library)	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	0.456795421203283	[]	[]	1	hSpCas9	negative selection	4089294
128702914	128702937	9	-	26780180	HT29	viability (GeCKOv2 library)	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	0.891600214991471	[]	[]	4	hSpCas9	negative selection	4089295
128707394	128707417	9	-	26780180	HT29	viability (GeCKOv2 library)	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.28489666055488	[]	[]	0	hSpCas9	negative selection	4089296
128706981	128707004	9	+	26780180	HT29	viability (GeCKOv2 library)	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	1.52255951820525	[]	[]	7	hSpCas9	negative selection	4089297
128702905	128702928	9	+	26780180	HT29	viability (GeCKOv2 library)	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.983802899678681	[]	[]	4	hSpCas9	negative selection	4089298
128707384	128707407	9	+	26780180	HT29	viability (GeCKOv2 library)	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.664883533623503	[]	[]	2	hSpCas9	negative selection	4089299
128706921	128706944	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.11859417698250832	[3]	[2,2]	-3	hSpCas9	positive selection	4160857
128702914	128702937	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.2395365844121982	[3]	[1,1]	-5	hSpCas9	positive selection	4160858
128706981	128707004	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.1610890498498776	[0]	[0,0]	-4	hSpCas9	positive selection	4160859
128702905	128702928	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.0977719944251938	[2]	[0,2]	2	hSpCas9	positive selection	4160860
128706921	128706944	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	0.31538564189414736	[3]	[5,4,0,0]	2	hSpCas9	positive selection	4224879
128702914	128702937	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.00079827190535392	[3]	[2,0,1,0]	0	hSpCas9	positive selection	4224880
128706981	128707004	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	1.1669202328532997	[0]	[0,0,0,0]	8	hSpCas9	positive selection	4224881
128702905	128702928	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.8823218078212633	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4224882
128706981	128707004	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.4491075386880996	[2]	[1,0]	-7	hSpCas9	positive selection	4290492
128707384	128707407	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.06101932088832364	[3]	[3,1]	1	hSpCas9	positive selection	4290493
128706921	128706944	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.25669168816002297	[5]	[3,2]	-5	hSpCas9	positive selection	4290494
128707394	128707417	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.29917426517627665	[2]	[2,2]	6	hSpCas9	positive selection	4354744
128702905	128702928	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.10281521798931215	[0]	[0,0]	2	hSpCas9	positive selection	4354745
128702914	128702937	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.5156721377796887	[2]	[2,0]	-8	hSpCas9	positive selection	4354746
128705408	128705430	9	+	27760321	OCIAML3	viability	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	0.39790825829178456	[1053,860]	[854,1146]	5	hSpCas9	negative selection	4428161
128705852	128705874	9	-	27760321	OCIAML3	viability	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	0.17862870120313423	[742,709]	[554,759]	2	hSpCas9	negative selection	4428162
128706982	128707004	9	+	27760321	OCIAML3	viability	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.37778125323368505	[395,359]	[219,236]	-4	hSpCas9	negative selection	4428163
128707390	128707412	9	-	27760321	OCIAML3	viability	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	0.35546054823882733	[474,411]	[403,492]	4	hSpCas9	negative selection	4428164
128714057	128714079	9	+	27760321	OCIAML3	viability	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	0.3078269915372972	[408,403]	[322,487]	3	hSpCas9	negative selection	4428165
128705408	128705430	9	+	27760321	OCIAML2	viability	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	0.4093509713208483	[1053,860]	[938,1134]	5	hSpCas9	negative selection	4511624
128705852	128705874	9	-	27760321	OCIAML2	viability	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	0.010816648050160693	[742,709]	[554,642]	0	hSpCas9	negative selection	4511625
128706982	128707004	9	+	27760321	OCIAML2	viability	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.1285138181852897	[395,359]	[219,357]	-2	hSpCas9	negative selection	4511626
128707390	128707412	9	-	27760321	OCIAML2	viability	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	-0.1289577791299644	[474,411]	[309,349]	-2	hSpCas9	negative selection	4511627
128714057	128714079	9	+	27760321	OCIAML2	viability	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	-0.1392384653424481	[408,403]	[279,324]	-2	hSpCas9	negative selection	4511628
128705408	128705430	9	+	27760321	MV411	viability	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	1.3228417796132539	[1053,860]	[1515,1657]	8	hSpCas9	negative selection	4595087
128705852	128705874	9	-	27760321	MV411	viability	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	0.8978428050986881	[742,709]	[842,971]	6	hSpCas9	negative selection	4595088
128706982	128707004	9	+	27760321	MV411	viability	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-1.2894947539664885	[395,359]	[79,134]	-7	hSpCas9	negative selection	4595089
128707390	128707412	9	-	27760321	MV411	viability	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	0.6622637231958238	[474,411]	[441,491]	5	hSpCas9	negative selection	4595090
128714057	128714079	9	+	27760321	MV411	viability	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	0.24172439138133206	[408,403]	[391,206]	1	hSpCas9	negative selection	4595091
128705408	128705430	9	+	27760321	HL60	viability	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	0.45342828431798865	[1053,860]	[954,1182]	5	hSpCas9	negative selection	4678550
128705852	128705874	9	-	27760321	HL60	viability	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	0.2756215745424643	[742,709]	[583,862]	3	hSpCas9	negative selection	4678551
128706982	128707004	9	+	27760321	HL60	viability	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.9599179223280557	[395,359]	[212,100]	-7	hSpCas9	negative selection	4678552
128707390	128707412	9	-	27760321	HL60	viability	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	0.020373930541127683	[474,411]	[349,383]	0	hSpCas9	negative selection	4678553
128714057	128714079	9	+	27760321	HL60	viability	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	-0.7211852441250094	[408,403]	[184,219]	-6	hSpCas9	negative selection	4678554
128705408	128705430	9	+	27760321	HT1080	viability	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	0.716825268032258	[860,671]	[361,654]	4	hSpCas9	negative selection	4762013
128705852	128705874	9	-	27760321	HT1080	viability	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	1.3263895411367408	[709,553]	[891,345]	7	hSpCas9	negative selection	4762014
128706982	128707004	9	+	27760321	HT1080	viability	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	1.3442205037519872	[359,280]	[0,677]	7	hSpCas9	negative selection	4762015
128707390	128707412	9	-	27760321	HT1080	viability	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	0.488247222131048	[411,321]	[143,271]	2	hSpCas9	negative selection	4762016
128714057	128714079	9	+	27760321	HT1080	viability	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	1.0643592457963782	[403,314]	[298,299]	6	hSpCas9	negative selection	4762017
128705408	128705430	9	+	27760321	HT29	viability after 7 days	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	0.43427264207093375	[860,671]	[1693,1220,1135]	6	hSpCas9	negative selection	4845476
128705852	128705874	9	-	27760321	HT29	viability after 7 days	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	-0.036318255617785455	[709,553]	[970,688,742]	0	hSpCas9	negative selection	4845477
128706982	128707004	9	+	27760321	HT29	viability after 7 days	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.9091779842421474	[359,280]	[409,146,130]	-8	hSpCas9	negative selection	4845478
128707390	128707412	9	-	27760321	HT29	viability after 7 days	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	-0.38249825766267626	[411,321]	[536,229,343]	-5	hSpCas9	negative selection	4845479
128714057	128714079	9	+	27760321	HT29	viability after 7 days	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	0.1036539558231559	[403,314]	[449,329,695]	1	hSpCas9	negative selection	4845480
128705408	128705430	9	+	27760321	HT29	viability after 25 days	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	0.7774773774882968	[860,671]	[1387,1313,1842]	8	hSpCas9	negative selection	4928939
128705852	128705874	9	-	27760321	HT29	viability after 25 days	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	0.14002687282012527	[709,553]	[631,1000,759]	1	hSpCas9	negative selection	4928940
128706982	128707004	9	+	27760321	HT29	viability after 25 days	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.4437105228237189	[359,280]	[182,316,317]	-4	hSpCas9	negative selection	4928941
128707390	128707412	9	-	27760321	HT29	viability after 25 days	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	-0.39556557269530673	[411,321]	[270,197,509]	-4	hSpCas9	negative selection	4928942
128714057	128714079	9	+	27760321	HT29	viability after 25 days	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	0.013375809170626734	[403,314]	[313,405,542]	0	hSpCas9	negative selection	4928943
128705408	128705430	9	+	27760321	HT29	viability after 22 days	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	0.9248503353232227	[860,671]	[1738,1751,1552]	9	hSpCas9	negative selection	5012402
128705852	128705874	9	-	27760321	HT29	viability after 22 days	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	0.0353945832011886	[709,553]	[596,731,922]	0	hSpCas9	negative selection	5012403
128706982	128707004	9	+	27760321	HT29	viability after 22 days	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.4017454684511035	[359,280]	[349,259,228]	-4	hSpCas9	negative selection	5012404
128707390	128707412	9	-	27760321	HT29	viability after 22 days	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	-0.19245280084090538	[411,321]	[433,227,450]	-2	hSpCas9	negative selection	5012405
128714057	128714079	9	+	27760321	HT29	viability after 22 days	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	-0.05463223379838354	[403,314]	[424,343,430]	0	hSpCas9	negative selection	5012406
128705408	128705430	9	+	27760321	HT29	viability after 19 days	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	0.9333668953192742	[860,671]	[1759,1750,1524]	8	hSpCas9	negative selection	5095865
128705852	128705874	9	-	27760321	HT29	viability after 19 days	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	0.3920763862448824	[709,553]	[896,980,960]	4	hSpCas9	negative selection	5095866
128706982	128707004	9	+	27760321	HT29	viability after 19 days	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	0.2895725048257347	[359,280]	[475,644,233]	2	hSpCas9	negative selection	5095867
128707390	128707412	9	-	27760321	HT29	viability after 19 days	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	-0.041989699547650944	[411,321]	[467,347,412]	0	hSpCas9	negative selection	5095868
128714057	128714079	9	+	27760321	HT29	viability after 19 days	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	0.3546640067078011	[403,314]	[278,506,755]	3	hSpCas9	negative selection	5095869
128705408	128705430	9	+	27760321	HT29	viability after 16 days	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	0.7439430989361517	[860,671]	[1286,1408,1598]	8	hSpCas9	negative selection	5179328
128705852	128705874	9	-	27760321	HT29	viability after 16 days	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	0.09099648595006171	[709,553]	[664,671,915]	0	hSpCas9	negative selection	5179329
128706982	128707004	9	+	27760321	HT29	viability after 16 days	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	0.2241601926208469	[359,280]	[477,268,518]	2	hSpCas9	negative selection	5179330
128707390	128707412	9	-	27760321	HT29	viability after 16 days	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	-0.4706280301249844	[411,321]	[178,214,485]	-5	hSpCas9	negative selection	5179331
128714057	128714079	9	+	27760321	HT29	viability after 16 days	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	-0.5783101180014195	[403,314]	[228,239,335]	-5	hSpCas9	negative selection	5179332
128705408	128705430	9	+	27760321	HT29	viability after 13 days	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	0.7681913477994489	[860,671]	[1340,1559,1634]	8	hSpCas9	negative selection	5262791
128705852	128705874	9	-	27760321	HT29	viability after 13 days	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	-0.12024499015478396	[709,553]	[646,572,795]	-1	hSpCas9	negative selection	5262792
128706982	128707004	9	+	27760321	HT29	viability after 13 days	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.22393526986308876	[359,280]	[383,322,251]	-3	hSpCas9	negative selection	5262793
128707390	128707412	9	-	27760321	HT29	viability after 13 days	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	-0.20202354152806687	[411,321]	[285,341,475]	-2	hSpCas9	negative selection	5262794
128714057	128714079	9	+	27760321	HT29	viability after 13 days	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	0.22403797628514044	[403,314]	[223,753,483]	2	hSpCas9	negative selection	5262795
128705408	128705430	9	+	27760321	HT29	viability after 10 days	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	0.6908975679899614	[860,671]	[1402,1498,1726]	8	hSpCas9	negative selection	5346254
128705852	128705874	9	-	27760321	HT29	viability after 10 days	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	-0.019023203836239344	[709,553]	[921,772,643]	0	hSpCas9	negative selection	5346255
128706982	128707004	9	+	27760321	HT29	viability after 10 days	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.764033420789633	[359,280]	[242,254,209]	-7	hSpCas9	negative selection	5346256
128707390	128707412	9	-	27760321	HT29	viability after 10 days	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	0.06059657562949597	[411,321]	[574,420,436]	0	hSpCas9	negative selection	5346257
128714057	128714079	9	+	27760321	HT29	viability after 10 days	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	-0.3643028598269967	[403,314]	[311,345,386]	-5	hSpCas9	negative selection	5346258
128705408	128705430	9	+	27760321	MOLM13	viability	GCCACAGACCGCCGCCACTTGG	PKN3	ENSG00000160447	0.37024954214651284	[1053,860]	[468,886]	2	hSpCas9	negative selection	5429717
128705852	128705874	9	-	27760321	MOLM13	viability	GGTGCCACTGGCGCACGTGTGG	PKN3	ENSG00000160447	1.1180927668188887	[742,709]	[1146,672]	7	hSpCas9	negative selection	5429718
128706982	128707004	9	+	27760321	MOLM13	viability	CTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.7634385685979548	[395,359]	[144,108]	-5	hSpCas9	negative selection	5429719
128707390	128707412	9	-	27760321	MOLM13	viability	GACTACCTGTTAGGGCGGTGGG	PKN3	ENSG00000160447	0.464537696805855	[474,411]	[365,325]	3	hSpCas9	negative selection	5429720
128714057	128714079	9	+	27760321	MOLM13	viability	CGATCCTGTCATTGAGAGGCGG	PKN3	ENSG00000160447	0.031555922685863824	[408,403]	[408,86]	0	hSpCas9	negative selection	5429721
128702767	128702790	9	+	27661255	K562	viability	GGCCAGCGGGTCTCGGGAGGGGG	PKN3	ENSG00000160447	-0.7954846999147148	[743,874]	[425,324]	-8	dCas9-KRAB	negative selection	5502194
128702935	128702958	9	+	27661255	K562	viability	GGCAGGTGAACGGCGTGGGAGGG	PKN3	ENSG00000160447	0.0027833957498542006	[415,360]	[328,296]	0	dCas9-KRAB	negative selection	5502195
128702505	128702528	9	-	27661255	K562	viability	GAGCCGGCCAGTTAGGGACAGGG	PKN3	ENSG00000160447	-0.04212104782731252	[1108,1467]	[1107,897]	-2	dCas9-KRAB	negative selection	5502196
128702595	128702618	9	-	27661255	K562	viability	GCGTGACCGCGCCTCACCCCCGG	PKN3	ENSG00000160447	0.09979033347811928	[597,603]	[522,506]	3	dCas9-KRAB	negative selection	5502197
128702986	128703009	9	-	27661255	K562	viability	GGGCTCCGGGGCGATGACAGAGG	PKN3	ENSG00000160447	0.14395318322073614	[826,891]	[830,694]	5	dCas9-KRAB	negative selection	5502198
128706981	128707004	9	+	27260156	BXPC3	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.4345152002549182	[227]	[121,147,222,225]	-7	hSpCas9	negative selection	5562952
128707384	128707407	9	+	27260156	BXPC3	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.09572801228527184	[530]	[528,480,692,693]	2	hSpCas9	negative selection	5562953
128706921	128706944	9	+	27260156	BXPC3	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.3110974027597295	[2043]	[1467,1564,1932,1985]	-6	hSpCas9	negative selection	5562954
128707394	128707417	9	-	27260156	BXPC3	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.4125143514518249	[284]	[214,206,195,284]	-7	hSpCas9	negative selection	5627204
128702905	128702928	9	+	27260156	BXPC3	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.20466954298359008	[58]	[118,52,60,42]	4	hSpCas9	negative selection	5627205
128702914	128702937	9	-	27260156	BXPC3	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.38646374535586003	[375]	[292,329,254,323]	-7	hSpCas9	negative selection	5627206
128706981	128707004	9	+	27260156	A673	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.36007553399831216	[227]	[266,186,160,246]	-7	hSpCas9	negative selection	5684203
128707384	128707407	9	+	27260156	A673	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.05177371297212793	[530]	[835,517,654,656]	1	hSpCas9	negative selection	5684204
128706921	128706944	9	+	27260156	A673	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.24848759982307111	[2043]	[2098,1914,2060,2199]	-6	hSpCas9	negative selection	5684205
128707394	128707417	9	-	27260156	A673	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.07950922243947112	[284]	[324,367,279,320]	-2	hSpCas9	negative selection	5748455
128702905	128702928	9	+	27260156	A673	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.2189700400699821	[58]	[82,46,59,55]	-5	hSpCas9	negative selection	5748456
128702914	128702937	9	-	27260156	A673	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	0.2149905045513058	[375]	[661,449,452,549]	5	hSpCas9	negative selection	5748457
128706981	128707004	9	+	27260156	A375	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.6258341448682618	[227]	[233,130,143,174]	-7	hSpCas9	negative selection	5805454
128707384	128707407	9	+	27260156	A375	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.4628545492806665	[530]	[858,876,855,829]	6	hSpCas9	negative selection	5805455
128706921	128706944	9	+	27260156	A375	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.5188166338465197	[2043]	[2451,1511,1494,1235]	-6	hSpCas9	negative selection	5805456
128707394	128707417	9	-	27260156	A375	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.020212977632642515	[284]	[327,214,341,401]	0	hSpCas9	negative selection	5869706
128702905	128702928	9	+	27260156	A375	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.21978736344680305	[58]	[32,28,63,100]	-3	hSpCas9	negative selection	5869707
128702914	128702937	9	-	27260156	A375	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.5259584859169482	[375]	[231,491,258,265]	-6	hSpCas9	negative selection	5869708
128706981	128707004	9	+	27260156	COLO741	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	0.003944262516703434	[227]	[243,269,352]	0	hSpCas9	negative selection	5926705
128707384	128707407	9	+	27260156	COLO741	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.172065073595074	[530]	[958,784,577]	3	hSpCas9	negative selection	5926706
128706921	128706944	9	+	27260156	COLO741	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.35942453788488704	[2043]	[2214,2181,1742]	-6	hSpCas9	negative selection	5926707
128707394	128707417	9	-	27260156	COLO741	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.10991766637698996	[284]	[525,366,302]	2	hSpCas9	negative selection	5990957
128702905	128702928	9	+	27260156	COLO741	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.15909103950156345	[58]	[66,62,71]	-3	hSpCas9	negative selection	5990958
128702914	128702937	9	-	27260156	COLO741	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	0.20639871858796086	[375]	[575,442,637]	4	hSpCas9	negative selection	5990959
128706981	128707004	9	+	27260156	CAL120	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.6108633474207341	[227]	[206,141,210]	-7	hSpCas9	negative selection	6047956
128707384	128707407	9	+	27260156	CAL120	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.7516648521117946	[530]	[1138,854,1342]	9	hSpCas9	negative selection	6047957
128706921	128706944	9	+	27260156	CAL120	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.20804199430927883	[2043]	[2014,1809,2741]	-3	hSpCas9	negative selection	6047958
128707394	128707417	9	-	27260156	CAL120	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.13612949064320023	[284]	[404,467,299]	2	hSpCas9	negative selection	6112208
128702905	128702928	9	+	27260156	CAL120	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.5807377684502977	[58]	[37,81,25]	-7	hSpCas9	negative selection	6112209
128702914	128702937	9	-	27260156	CAL120	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	0.08129707146282578	[375]	[521,421,543]	1	hSpCas9	negative selection	6112210
128706981	128707004	9	+	27260156	CADOES1	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.7394803152191827	[227]	[116,48,160,182]	-8	hSpCas9	negative selection	6169207
128707384	128707407	9	+	27260156	CADOES1	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.30576716289012107	[530]	[567,556,725,589]	5	hSpCas9	negative selection	6169208
128706921	128706944	9	+	27260156	CADOES1	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.4805364389735247	[2043]	[1266,1219,1316,1656]	-7	hSpCas9	negative selection	6169209
128707394	128707417	9	-	27260156	CADOES1	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.2402620212000831	[284]	[199,177,283,235]	-4	hSpCas9	negative selection	6233459
128702905	128702928	9	+	27260156	CADOES1	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.951824951789439	[58]	[20,25,24,41]	-9	hSpCas9	negative selection	6233460
128702914	128702937	9	-	27260156	CADOES1	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.4314524700965835	[375]	[224,298,238,274]	-6	hSpCas9	negative selection	6233461
128706981	128707004	9	+	27260156	EWS502	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	0.16987799044189433	[227]	[317,293,290,168]	3	hSpCas9	negative selection	6290458
128707384	128707407	9	+	27260156	EWS502	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.19760696618753942	[530]	[446,685,635,844]	3	hSpCas9	negative selection	6290459
128706921	128706944	9	+	27260156	EWS502	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.2549649604505808	[2043]	[1642,1451,2358,1840]	-4	hSpCas9	negative selection	6290460
128707394	128707417	9	-	27260156	EWS502	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.02007406906668796	[284]	[282,368,328,200]	0	hSpCas9	negative selection	6354710
128702905	128702928	9	+	27260156	EWS502	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.10769098053936021	[58]	[10,39,148,78]	1	hSpCas9	negative selection	6354711
128702914	128702937	9	-	27260156	EWS502	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.31434172780503333	[375]	[219,279,440,356]	-5	hSpCas9	negative selection	6354712
128706981	128707004	9	+	27260156	EW8	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.1911872324198367	[227]	[207,194,121,133]	-4	hSpCas9	negative selection	6411709
128707384	128707407	9	+	27260156	EW8	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.3626704104830444	[530]	[1088,419,409,375]	6	hSpCas9	negative selection	6411710
128706921	128706944	9	+	27260156	EW8	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.23361376014026858	[2043]	[1695,1430,1161,1415]	-4	hSpCas9	negative selection	6411711
128707394	128707417	9	-	27260156	EW8	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.21894322189335313	[284]	[222,169,196,205]	-4	hSpCas9	negative selection	6475961
128702905	128702928	9	+	27260156	EW8	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.3515020383013807	[58]	[28,73,56,80]	6	hSpCas9	negative selection	6475962
128702914	128702937	9	-	27260156	EW8	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.36353368625578775	[375]	[271,263,271,136]	-6	hSpCas9	negative selection	6475963
128706981	128707004	9	+	27260156	CORL105	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.16550977980517678	[227]	[339,272,198,136]	-3	hSpCas9	negative selection	6532960
128707384	128707407	9	+	27260156	CORL105	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.09285527451446468	[530]	[738,507,750,672]	1	hSpCas9	negative selection	6532961
128706921	128706944	9	+	27260156	CORL105	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.40258205712281714	[2043]	[2026,1703,2083,1478]	-6	hSpCas9	negative selection	6532962
128707394	128707417	9	-	27260156	CORL105	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.05126176801441007	[284]	[221,374,429,363]	0	hSpCas9	negative selection	6597212
128702905	128702928	9	+	27260156	CORL105	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.30501260284255727	[58]	[95,36,119,94]	5	hSpCas9	negative selection	6597213
128702914	128702937	9	-	27260156	CORL105	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.04854375821416479	[375]	[472,356,411,460]	-1	hSpCas9	negative selection	6597214
128706981	128707004	9	+	27260156	HS294T	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.40661306116414964	[227]	[18,32,160,56]	-5	hSpCas9	negative selection	6654211
128707384	128707407	9	+	27260156	HS294T	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.10993958773573631	[530]	[233,169,260,220]	1	hSpCas9	negative selection	6654212
128706921	128706944	9	+	27260156	HS294T	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.14557518721846763	[2043]	[660,527,733,989]	-2	hSpCas9	negative selection	6654213
128707394	128707417	9	-	27260156	HS294T	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.565874489511928	[284]	[55,66,74,106]	-7	hSpCas9	negative selection	6718463
128702905	128702928	9	+	27260156	HS294T	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.6466451788907324	[58]	[15,4,9,29]	-7	hSpCas9	negative selection	6718464
128702914	128702937	9	-	27260156	HS294T	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.824005338448042	[375]	[53,84,108,82]	-8	hSpCas9	negative selection	6718465
128706981	128707004	9	+	27260156	HCC44	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.23514758651972967	[227]	[307,250,108,191]	-4	hSpCas9	negative selection	6775462
128707384	128707407	9	+	27260156	HCC44	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.4645873764293339	[530]	[830,846,905,737]	7	hSpCas9	negative selection	6775463
128706921	128706944	9	+	27260156	HCC44	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.3357885936287164	[2043]	[1935,1614,2088,1758]	-5	hSpCas9	negative selection	6775464
128707394	128707417	9	-	27260156	HCC44	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.015546824248050095	[284]	[240,399,377,273]	0	hSpCas9	negative selection	6839714
128702905	128702928	9	+	27260156	HCC44	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.02734063670263165	[58]	[63,50,121,36]	0	hSpCas9	negative selection	6839715
128702914	128702937	9	-	27260156	HCC44	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.010273669403873031	[375]	[363,446,512,369]	0	hSpCas9	negative selection	6839716
128706981	128707004	9	+	27260156	G402	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	0.158350060229978	[227]	[63,221,497,410]	2	hSpCas9	negative selection	6896713
128707384	128707407	9	+	27260156	G402	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.3744344968739787	[530]	[600,1651,463,660]	5	hSpCas9	negative selection	6896714
128706921	128706944	9	+	27260156	G402	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.7271420194334834	[2043]	[1729,1339,1584,1393]	-7	hSpCas9	negative selection	6896715
128707394	128707417	9	-	27260156	G402	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.31154205710419947	[284]	[250,526,200,156]	-4	hSpCas9	negative selection	6960965
128702905	128702928	9	+	27260156	G402	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-1.5001252095913173	[58]	[3,0,83,8]	-9	hSpCas9	negative selection	6960966
128702914	128702937	9	-	27260156	G402	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-1.5406486162563562	[375]	[175,250,153,61]	-9	hSpCas9	negative selection	6960967
128706981	128707004	9	+	27260156	L33	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.6468452087492307	[227]	[107,66,81,180]	-9	hSpCas9	negative selection	7017964
128707384	128707407	9	+	27260156	L33	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.24556584098309814	[530]	[563,267,434,609]	5	hSpCas9	negative selection	7017965
128706921	128706944	9	+	27260156	L33	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.21667918937116393	[2043]	[1680,706,1183,1747]	-5	hSpCas9	negative selection	7017966
128707394	128707417	9	-	27260156	L33	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.027824647450813145	[284]	[240,113,190,295]	0	hSpCas9	negative selection	7082216
128702905	128702928	9	+	27260156	L33	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.3934850119675093	[58]	[74,21,13,27]	-7	hSpCas9	negative selection	7082217
128702914	128702937	9	-	27260156	L33	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	0.017157401294844776	[375]	[444,157,233,317]	0	hSpCas9	negative selection	7082218
128706981	128707004	9	+	27260156	K562	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.08068639659358179	[227]	[405,108,120,146]	-1	hSpCas9	negative selection	7139215
128707384	128707407	9	+	27260156	K562	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.49390233055280197	[530]	[765,907,374,627]	6	hSpCas9	negative selection	7139216
128706921	128706944	9	+	27260156	K562	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.28206909252488743	[2043]	[1574,1527,1398,1469]	-3	hSpCas9	negative selection	7139217
128707394	128707417	9	-	27260156	K562	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.5956672060958322	[284]	[105,403,53,117]	-6	hSpCas9	negative selection	7203467
128702905	128702928	9	+	27260156	K562	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.8400840214340213	[58]	[21,48,32,14]	-7	hSpCas9	negative selection	7203468
128702914	128702937	9	-	27260156	K562	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.6230228616313012	[375]	[151,323,238,157]	-6	hSpCas9	negative selection	7203469
128706981	128707004	9	+	27260156	HT29	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	0.053042272751971375	[227]	[200,208,457,268]	1	hSpCas9	negative selection	7260466
128707384	128707407	9	+	27260156	HT29	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.25291755719260617	[530]	[898,739,799,653]	5	hSpCas9	negative selection	7260467
128706921	128706944	9	+	27260156	HT29	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.3536915199268089	[2043]	[2047,2004,1968,1775]	-6	hSpCas9	negative selection	7260468
128707394	128707417	9	-	27260156	HT29	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.045820719127040443	[284]	[310,386,330,315]	-1	hSpCas9	negative selection	7324718
128702905	128702928	9	+	27260156	HT29	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.27399044416891494	[58]	[37,73,87,38]	-5	hSpCas9	negative selection	7324719
128702914	128702937	9	-	27260156	HT29	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.5463544437890402	[375]	[286,328,319,312]	-7	hSpCas9	negative selection	7324720
128706981	128707004	9	+	27260156	MHHES1	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	0.1311416237732005	[227]	[258,373,252,246]	2	hSpCas9	negative selection	7381717
128707384	128707407	9	+	27260156	MHHES1	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.19977859541837356	[530]	[722,676,725,623]	3	hSpCas9	negative selection	7381718
128706921	128706944	9	+	27260156	MHHES1	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.34441049027496207	[2043]	[1906,2086,1788,1532]	-6	hSpCas9	negative selection	7381719
128707394	128707417	9	-	27260156	MHHES1	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.17970341748289953	[284]	[280,470,237,179]	-3	hSpCas9	negative selection	7445969
128702905	128702928	9	+	27260156	MHHES1	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.5163542123487814	[58]	[63,22,7,80]	-7	hSpCas9	negative selection	7445970
128702914	128702937	9	-	27260156	MHHES1	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.7695276620819277	[375]	[409,251,213,153]	-8	hSpCas9	negative selection	7445971
128706981	128707004	9	+	27260156	MEWO	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.467893126782408	[227]	[136,216,104]	-7	hSpCas9	negative selection	7502968
128707384	128707407	9	+	27260156	MEWO	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.2157608268487079	[530]	[858,430,495]	5	hSpCas9	negative selection	7502969
128706921	128706944	9	+	27260156	MEWO	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.30837207903990804	[2043]	[1853,1437,1400]	-6	hSpCas9	negative selection	7502970
128707394	128707417	9	-	27260156	MEWO	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.03769347200293127	[284]	[385,227,228]	0	hSpCas9	negative selection	7567220
128702905	128702928	9	+	27260156	MEWO	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.32852173212224356	[58]	[176,25,25]	7	hSpCas9	negative selection	7567221
128702914	128702937	9	-	27260156	MEWO	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.006537267870577956	[375]	[512,351,216]	0	hSpCas9	negative selection	7567222
128706981	128707004	9	+	27260156	LNCAPCLONEFGC	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.1357560745518147	[227]	[96,244,168,235]	-2	hSpCas9	negative selection	7624219
128707384	128707407	9	+	27260156	LNCAPCLONEFGC	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.3854485527139515	[530]	[774,574,718,457]	6	hSpCas9	negative selection	7624220
128706921	128706944	9	+	27260156	LNCAPCLONEFGC	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.4171595793424059	[2043]	[991,1364,1637,1596]	-6	hSpCas9	negative selection	7624221
128707394	128707417	9	-	27260156	LNCAPCLONEFGC	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.07211203630198382	[284]	[302,252,277,252]	1	hSpCas9	negative selection	7688471
128702905	128702928	9	+	27260156	LNCAPCLONEFGC	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.03364269137145737	[58]	[19,25,58,116]	0	hSpCas9	negative selection	7688472
128702914	128702937	9	-	27260156	LNCAPCLONEFGC	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.6496174291172812	[375]	[202,169,272,233]	-7	hSpCas9	negative selection	7688473
128706981	128707004	9	+	27260156	PANC0327	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.1089217952024748	[227]	[235,127,261,136]	-2	hSpCas9	negative selection	7745470
128707384	128707407	9	+	27260156	PANC0327	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.36271149061270735	[530]	[451,590,553,817]	5	hSpCas9	negative selection	7745471
128706921	128706944	9	+	27260156	PANC0327	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.4472138812903754	[2043]	[1551,1255,1129,1415]	-6	hSpCas9	negative selection	7745472
128707394	128707417	9	-	27260156	PANC0327	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.0907628631108991	[284]	[311,195,144,437]	1	hSpCas9	negative selection	7809722
128702905	128702928	9	+	27260156	PANC0327	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	1.2448634460911385	[58]	[214,34,228,36]	9	hSpCas9	negative selection	7809723
128702914	128702937	9	-	27260156	PANC0327	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.1704883662717333	[375]	[399,368,180,235]	-3	hSpCas9	negative selection	7809724
128706981	128707004	9	+	27260156	NCIH2009	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.4458551651469014	[227]	[172,242,272]	-5	hSpCas9	negative selection	7866721
128707384	128707407	9	+	27260156	NCIH2009	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.34936091574353656	[530]	[1031,837,982]	5	hSpCas9	negative selection	7866722
128706921	128706944	9	+	27260156	NCIH2009	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.37065188462897214	[2043]	[2613,2518,1563]	-5	hSpCas9	negative selection	7866723
128707394	128707417	9	-	27260156	NCIH2009	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.702451438127106	[284]	[224,287,215]	-7	hSpCas9	negative selection	7930973
128702905	128702928	9	+	27260156	NCIH2009	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.17942410317920077	[58]	[72,88,55]	-2	hSpCas9	negative selection	7930974
128702914	128702937	9	-	27260156	NCIH2009	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.31650599171540517	[375]	[507,523,247]	-4	hSpCas9	negative selection	7930975
128706981	128707004	9	+	27260156	NCIH1373	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	0.20776985852023278	[227]	[216,320,128,134]	2	hSpCas9	negative selection	7987972
128707384	128707407	9	+	27260156	NCIH1373	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.9946522104697697	[530]	[1105,1439,1181,250]	8	hSpCas9	negative selection	7987973
128706921	128706944	9	+	27260156	NCIH1373	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.6606612957185545	[2043]	[1359,991,1643,485]	-6	hSpCas9	negative selection	7987974
128707394	128707417	9	-	27260156	NCIH1373	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.4591414671809201	[284]	[135,247,209,84]	-4	hSpCas9	negative selection	8052224
128702905	128702928	9	+	27260156	NCIH1373	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-1.6988174884171503	[58]	[6,30,20,4]	-9	hSpCas9	negative selection	8052225
128702914	128702937	9	-	27260156	NCIH1373	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-1.4042708894518912	[375]	[124,220,132,37]	-8	hSpCas9	negative selection	8052226
128706981	128707004	9	+	27260156	PATU8902	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.33455737939094554	[227]	[169,377,178,304]	-3	hSpCas9	negative selection	8109223
128707384	128707407	9	+	27260156	PATU8902	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.867035951282294	[530]	[1316,2130,866,1176]	8	hSpCas9	negative selection	8109224
128706921	128706944	9	+	27260156	PATU8902	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.49062669231026446	[2043]	[1866,1834,1373,3339]	-5	hSpCas9	negative selection	8109225
128707394	128707417	9	-	27260156	PATU8902	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.6328099138730446	[284]	[304,190,222,317]	-6	hSpCas9	negative selection	8173475
128702905	128702928	9	+	27260156	PATU8902	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-3.1135780023840107	[58]	[2,10,17,2]	-9	hSpCas9	negative selection	8173476
128702914	128702937	9	-	27260156	PATU8902	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.8791061900417149	[375]	[429,251,102,411]	-7	hSpCas9	negative selection	8173477
128706981	128707004	9	+	27260156	PANC1	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.5299476740245908	[227]	[136,167,68,166]	-7	hSpCas9	negative selection	8230474
128707384	128707407	9	+	27260156	PANC1	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.21303939677015243	[530]	[524,798,567,306]	3	hSpCas9	negative selection	8230475
128706921	128706944	9	+	27260156	PANC1	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.3593556947447989	[2043]	[1136,1679,1566,1170]	-5	hSpCas9	negative selection	8230476
128707394	128707417	9	-	27260156	PANC1	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.015221587586136232	[284]	[294,227,235,224]	0	hSpCas9	negative selection	8294726
128702905	128702928	9	+	27260156	PANC1	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.30754203204209274	[58]	[14,49,41,55]	-5	hSpCas9	negative selection	8294727
128702914	128702937	9	-	27260156	PANC1	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.4975175739873582	[375]	[156,354,260,174]	-6	hSpCas9	negative selection	8294728
128706981	128707004	9	+	27260156	PANC0813	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.03861838073990631	[227]	[155,456,222,199]	0	hSpCas9	negative selection	8351725
128707384	128707407	9	+	27260156	PANC0813	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.2219308351357297	[530]	[659,743,743,752]	3	hSpCas9	negative selection	8351726
128706921	128706944	9	+	27260156	PANC0813	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.12456973616109202	[2043]	[2025,2138,2207,2404]	-2	hSpCas9	negative selection	8351727
128707394	128707417	9	-	27260156	PANC0813	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.24105096811531757	[284]	[312,334,170,313]	-4	hSpCas9	negative selection	8415977
128702905	128702928	9	+	27260156	PANC0813	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.45665017972840793	[58]	[97,76,133,72]	7	hSpCas9	negative selection	8415978
128702914	128702937	9	-	27260156	PANC0813	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.9375862543264241	[375]	[230,244,198,245]	-8	hSpCas9	negative selection	8415979
128706981	128707004	9	+	27260156	RDES	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.571159775806368	[227]	[153,170,166,219]	-7	hSpCas9	negative selection	8472976
128707384	128707407	9	+	27260156	RDES	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.4900288946543142	[530]	[853,716,831,1039]	7	hSpCas9	negative selection	8472977
128706921	128706944	9	+	27260156	RDES	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.4771110859857193	[2043]	[1467,1734,1638,1937]	-7	hSpCas9	negative selection	8472978
128707394	128707417	9	-	27260156	RDES	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.27282572961390705	[284]	[278,277,265,245]	-5	hSpCas9	negative selection	8537228
128702905	128702928	9	+	27260156	RDES	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.18695327573602594	[58]	[60,53,44,78]	-3	hSpCas9	negative selection	8537229
128702914	128702937	9	-	27260156	RDES	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.7746743545741938	[375]	[255,196,288,268]	-8	hSpCas9	negative selection	8537230
128706981	128707004	9	+	27260156	PC3	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.2628972172836428	[227]	[174,172,296,132]	-5	hSpCas9	negative selection	8594227
128707384	128707407	9	+	27260156	PC3	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.3430762898800124	[530]	[377,539,1437,707]	7	hSpCas9	negative selection	8594228
128706921	128706944	9	+	27260156	PC3	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.22355493735811804	[2043]	[1165,1845,2729,1684]	-5	hSpCas9	negative selection	8594229
128707394	128707417	9	-	27260156	PC3	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.13978153887328515	[284]	[269,288,485,250]	3	hSpCas9	negative selection	8658479
128702905	128702928	9	+	27260156	PC3	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.08935507789276276	[58]	[63,77,35,49]	2	hSpCas9	negative selection	8658480
128702914	128702937	9	-	27260156	PC3	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	0.4014152637145032	[375]	[236,550,903,519]	8	hSpCas9	negative selection	8658481
128706981	128707004	9	+	27260156	PATU8988T	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.5203980355679034	[227]	[236,167,97,109]	-7	hSpCas9	negative selection	8715478
128707384	128707407	9	+	27260156	PATU8988T	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.1198942174675961	[530]	[445,590,570,630]	2	hSpCas9	negative selection	8715479
128706921	128706944	9	+	27260156	PATU8988T	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.2193481406975204	[2043]	[1828,1968,1512,1485]	-4	hSpCas9	negative selection	8715480
128707394	128707417	9	-	27260156	PATU8988T	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.11473215471235487	[284]	[308,237,472,152]	2	hSpCas9	negative selection	8779730
128702905	128702928	9	+	27260156	PATU8988T	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.2546483125974186	[58]	[45,78,15,53]	-4	hSpCas9	negative selection	8779731
128702914	128702937	9	-	27260156	PATU8988T	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.07199770426557345	[375]	[185,337,416,447]	-1	hSpCas9	negative selection	8779732
128706981	128707004	9	+	27260156	T47D	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.7486638293484607	[227]	[127,177,171,151]	-9	hSpCas9	negative selection	8836729
128707384	128707407	9	+	27260156	T47D	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.2568474319489179	[530]	[815,623,846,675]	5	hSpCas9	negative selection	8836730
128706921	128706944	9	+	27260156	T47D	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.5489899264899079	[2043]	[1652,1499,1579,1793]	-8	hSpCas9	negative selection	8836731
128707394	128707417	9	-	27260156	T47D	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.03197356911280991	[284]	[310,319,398,327]	0	hSpCas9	negative selection	8900981
128702905	128702928	9	+	27260156	T47D	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.8292788215266675	[58]	[35,21,55,41]	-9	hSpCas9	negative selection	8900982
128702914	128702937	9	-	27260156	T47D	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.37157138966606285	[375]	[314,295,380,365]	-7	hSpCas9	negative selection	8900983
128706981	128707004	9	+	27260156	SU8686	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.08542743659805518	[227]	[230,314,129,145]	-1	hSpCas9	negative selection	8957980
128707384	128707407	9	+	27260156	SU8686	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.30949549895652373	[530]	[551,620,608,872]	5	hSpCas9	negative selection	8957981
128706921	128706944	9	+	27260156	SU8686	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.30523224828578854	[2043]	[1508,1668,1575,1834]	-5	hSpCas9	negative selection	8957982
128707394	128707417	9	-	27260156	SU8686	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.8608848758358304	[284]	[144,136,179,164]	-8	hSpCas9	negative selection	9022232
128702905	128702928	9	+	27260156	SU8686	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.39691713804039885	[58]	[28,46,59,42]	-6	hSpCas9	negative selection	9022233
128702914	128702937	9	-	27260156	SU8686	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.15372841803526904	[375]	[350,312,271,413]	-3	hSpCas9	negative selection	9022234
128706981	128707004	9	+	27260156	SKES1	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.325866004158341	[227]	[358,139,177,78]	-6	hSpCas9	negative selection	9079231
128707384	128707407	9	+	27260156	SKES1	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.08590930939128366	[530]	[680,554,401,615]	2	hSpCas9	negative selection	9079232
128706921	128706944	9	+	27260156	SKES1	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.6738492578153492	[2043]	[1567,1324,1199,1076]	-9	hSpCas9	negative selection	9079233
128707394	128707417	9	-	27260156	SKES1	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	-0.39317689916174337	[284]	[226,267,149,225]	-7	hSpCas9	negative selection	9143483
128702905	128702928	9	+	27260156	SKES1	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.35483122033724035	[58]	[56,48,132,56]	7	hSpCas9	negative selection	9143484
128702914	128702937	9	-	27260156	SKES1	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.04855858220592019	[375]	[634,361,266,236]	-1	hSpCas9	negative selection	9143485
128706981	128707004	9	+	27260156	TOV112D	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.5353087061580513	[227]	[203,101,147,165]	-8	hSpCas9	negative selection	9200482
128707384	128707407	9	+	27260156	TOV112D	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.0267046808074351	[530]	[505,698,533,464]	0	hSpCas9	negative selection	9200483
128706921	128706944	9	+	27260156	TOV112D	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.1149400604433799	[2043]	[1541,2699,1582,1902]	-2	hSpCas9	negative selection	9200484
128707394	128707417	9	-	27260156	TOV112D	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.14981733915692141	[284]	[311,337,302,317]	3	hSpCas9	negative selection	9264734
128702905	128702928	9	+	27260156	TOV112D	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.2810458164687941	[58]	[30,139,41,86]	5	hSpCas9	negative selection	9264735
128702914	128702937	9	-	27260156	TOV112D	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.1417496141109968	[375]	[349,541,220,302]	-3	hSpCas9	negative selection	9264736
128706981	128707004	9	+	27260156	TC71	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	-0.24320990201470605	[227]	[210,184,175,257]	-6	hSpCas9	negative selection	9321733
128707384	128707407	9	+	27260156	TC71	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.0439507709132991	[530]	[565,570,507,712]	1	hSpCas9	negative selection	9321734
128706921	128706944	9	+	27260156	TC71	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.237987999708972	[2043]	[1648,1963,1866,1961]	-6	hSpCas9	negative selection	9321735
128707394	128707417	9	-	27260156	TC71	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.1166860946469831	[284]	[374,323,345,274]	3	hSpCas9	negative selection	9385985
128702905	128702928	9	+	27260156	TC71	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.09419668413259341	[58]	[94,52,42,79]	2	hSpCas9	negative selection	9385986
128702914	128702937	9	-	27260156	TC71	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	0.5731722816667146	[375]	[474,640,529,767]	9	hSpCas9	negative selection	9385987
128706981	128707004	9	+	27260156	TC32	viability	GCTTAGTAGCCGGAGAACACAGG	PKN3	ENSG00000160447	0.09465676726082295	[227]	[209,231,234,224]	1	hSpCas9	negative selection	9442984
128707384	128707407	9	+	27260156	TC32	viability	GTGAAGCCCACCGCCCTAACAGG	PKN3	ENSG00000160447	0.1358953980083405	[530]	[552,435,516,697]	2	hSpCas9	negative selection	9442985
128706921	128706944	9	+	27260156	TC32	viability	ACAGCATCGACTGCACGTTGAGG	PKN3	ENSG00000160447	-0.197618484914581	[2043]	[1579,1349,2187,1704]	-4	hSpCas9	negative selection	9442986
128707394	128707417	9	-	27260156	TC32	viability	CTTCTGACTACCTGTTAGGGCGG	PKN3	ENSG00000160447	0.08898309105732105	[284]	[358,192,400,209]	1	hSpCas9	negative selection	9507236
128702905	128702928	9	+	27260156	TC32	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.9988987435448848	[58]	[31,5,53,29]	-9	hSpCas9	negative selection	9507237
128702914	128702937	9	-	27260156	TC32	viability	CCGCGGCGCCCCCTCCTCCATGG	PKN3	ENSG00000160447	-0.6094035428077322	[375]	[283,80,363,259]	-8	hSpCas9	negative selection	9507238
128705332	128705355	9	+	27869803	HPAFII	viability after 27 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-2.4272176230710008	[225]	[38,7,NaN]	-8	hSpCas9	negative selection	9604621
128705753	128705776	9	-	27869803	HPAFII	viability after 27 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	-0.510215250314139	[181]	[52,78,NaN]	-4	hSpCas9	negative selection	9604622
128706748	128706771	9	+	27869803	HPAFII	viability after 27 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	-1.1204430883834409	[596]	[115,167,NaN]	-6	hSpCas9	negative selection	9604623
128706990	128707013	9	+	27869803	HPAFII	viability after 27 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	-0.027101073917477514	[489]	[104,375,NaN]	0	hSpCas9	negative selection	9604624
128707391	128707414	9	-	27869803	HPAFII	viability after 27 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.23302042647449692	[255]	[119,189,NaN]	1	hSpCas9	negative selection	9604625
128713159	128713182	9	+	27869803	HPAFII	viability after 27 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	0.03187374725584391	[421]	[174,269,NaN]	0	hSpCas9	negative selection	9604626
128705332	128705355	9	+	27869803	HPAFII	viability after 15 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-0.48011149122700814	[225]	[339,70,NaN]	-5	hSpCas9	negative selection	9687070
128705753	128705776	9	-	27869803	HPAFII	viability after 15 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	-0.4211240519963271	[181]	[142,147,NaN]	-4	hSpCas9	negative selection	9687071
128706748	128706771	9	+	27869803	HPAFII	viability after 15 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	-0.6103391277982844	[596]	[431,412,NaN]	-6	hSpCas9	negative selection	9687072
128706990	128707013	9	+	27869803	HPAFII	viability after 15 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	-0.5008711121103038	[489]	[373,370,NaN]	-5	hSpCas9	negative selection	9687073
128707391	128707414	9	-	27869803	HPAFII	viability after 15 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	-0.08499267715557172	[255]	[333,212,NaN]	-1	hSpCas9	negative selection	9687074
128713159	128713182	9	+	27869803	HPAFII	viability after 15 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	0.025002898066124435	[421]	[614,365,NaN]	0	hSpCas9	negative selection	9687075
128705332	128705355	9	+	27869803	ASPC1	viability after 36 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	1.049372188346373	[259]	[134,382,67]	8	hSpCas9	negative selection	9769519
128705753	128705776	9	-	27869803	ASPC1	viability after 36 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	-1.0563205670354923	[524]	[171,46,60]	-7	hSpCas9	negative selection	9769520
128706748	128706771	9	+	27869803	ASPC1	viability after 36 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	1.1783674070946448	[778]	[1015,438,467]	9	hSpCas9	negative selection	9769521
128706990	128707013	9	+	27869803	ASPC1	viability after 36 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.06488254531131166	[1054]	[858,360,67]	0	hSpCas9	negative selection	9769522
128707391	128707414	9	-	27869803	ASPC1	viability after 36 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.3424288774196098	[657]	[154,436,267]	3	hSpCas9	negative selection	9769523
128713159	128713182	9	+	27869803	ASPC1	viability after 36 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	0.16793470713530212	[907]	[332,386,343]	1	hSpCas9	negative selection	9769524
128705332	128705355	9	+	27869803	PATU8988S	viability after 35 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-0.34519462740765505	[294]	[105,80,NaN]	-4	hSpCas9	negative selection	9851968
128705753	128705776	9	-	27869803	PATU8988S	viability after 35 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.19205780602028397	[418]	[96,288,NaN]	2	hSpCas9	negative selection	9851969
128706748	128706771	9	+	27869803	PATU8988S	viability after 35 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	0.34953864733887996	[843]	[481,383,NaN]	4	hSpCas9	negative selection	9851970
128706990	128707013	9	+	27869803	PATU8988S	viability after 35 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	-0.660480239250873	[908]	[283,178,NaN]	-6	hSpCas9	negative selection	9851971
128707391	128707414	9	-	27869803	PATU8988S	viability after 35 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.1884749477860298	[451]	[184,229,NaN]	2	hSpCas9	negative selection	9851972
128713159	128713182	9	+	27869803	PATU8988S	viability after 35 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	-0.2744059831550264	[864]	[303,271,NaN]	-3	hSpCas9	negative selection	9851973
128705332	128705355	9	+	27869803	PATU8988S	viability after 31 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-0.2465350402968488	[294]	[59,148,NaN]	-3	hSpCas9	negative selection	9934417
128705753	128705776	9	-	27869803	PATU8988S	viability after 31 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.35512375638033983	[418]	[130,318,NaN]	4	hSpCas9	negative selection	9934418
128706748	128706771	9	+	27869803	PATU8988S	viability after 31 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	0.6701260401355131	[843]	[465,623,NaN]	7	hSpCas9	negative selection	9934419
128706990	128707013	9	+	27869803	PATU8988S	viability after 31 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	-0.6202049895101672	[908]	[270,190,NaN]	-6	hSpCas9	negative selection	9934420
128707391	128707414	9	-	27869803	PATU8988S	viability after 31 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	0.7769358189784852	[451]	[237,398,NaN]	8	hSpCas9	negative selection	9934421
128713159	128713182	9	+	27869803	PATU8988S	viability after 31 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	-0.03131151372546648	[864]	[278,411,NaN]	0	hSpCas9	negative selection	9934422
128705332	128705355	9	+	27869803	HPAFII	viability after 35 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-2.1085569836729996	[225]	[26,25,NaN]	-8	hSpCas9	negative selection	10016866
128705753	128705776	9	-	27869803	HPAFII	viability after 35 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	0.1435851499489742	[181]	[10,203,NaN]	0	hSpCas9	negative selection	10016867
128706748	128706771	9	+	27869803	HPAFII	viability after 35 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	-1.2888475871311984	[596]	[102,146,NaN]	-6	hSpCas9	negative selection	10016868
128706990	128707013	9	+	27869803	HPAFII	viability after 35 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	0.635497651453321	[489]	[33,780,NaN]	4	hSpCas9	negative selection	10016869
128707391	128707414	9	-	27869803	HPAFII	viability after 35 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	-0.4463761236859688	[255]	[80,110,NaN]	-3	hSpCas9	negative selection	10016870
128713159	128713182	9	+	27869803	HPAFII	viability after 35 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	-0.49649549016881894	[421]	[70,241,NaN]	-3	hSpCas9	negative selection	10016871
128705332	128705355	9	+	27869803	HPAFII	viability after 31 days	TGAGAAGGAGGTGATCCGCCGGG	PKN3	ENSG00000160447	-1.2782657704882021	[225]	[69,32,NaN]	-6	hSpCas9	negative selection	10099315
128705753	128705776	9	-	27869803	HPAFII	viability after 31 days	TGAGCTGCTCTGCCCACGGCCGG	PKN3	ENSG00000160447	-0.36141086886588714	[181]	[34,127,NaN]	-2	hSpCas9	negative selection	10099316
128706748	128706771	9	+	27869803	HPAFII	viability after 31 days	GCGGGACAGCCAGCTGAAGGTGG	PKN3	ENSG00000160447	-1.121094842912651	[596]	[98,213,NaN]	-6	hSpCas9	negative selection	10099317
128706990	128707013	9	+	27869803	HPAFII	viability after 31 days	CCGGAGAACACAGGACCGCAAGG	PKN3	ENSG00000160447	-0.0021915100108630403	[489]	[52,515,NaN]	0	hSpCas9	negative selection	10099318
128707391	128707414	9	-	27869803	HPAFII	viability after 31 days	CTGACTACCTGTTAGGGCGGTGG	PKN3	ENSG00000160447	-0.11654694978628487	[255]	[132,131,NaN]	-1	hSpCas9	negative selection	10099319
128713159	128713182	9	+	27869803	HPAFII	viability after 31 days	ACCAAGGCCAAGCACCAGCGTGG	PKN3	ENSG00000160447	-0.11831515499191825	[421]	[65,383,NaN]	-1	hSpCas9	negative selection	10099320
128705362	128705385	9	+	28162770	P31FUJ	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	-0.4632860381043744	[148]	[126]	-4	hSpCas9	negative selection	10211971
128713557	128713580	9	-	28162770	P31FUJ	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-0.39326687660762477	[360]	[322]	-4	hSpCas9	negative selection	10211972
128715196	128715219	9	-	28162770	P31FUJ	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	0.42220779383503404	[133]	[210]	5	hSpCas9	negative selection	10211973
128702905	128702928	9	+	28162770	P31FUJ	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.030232201419415294	[179]	[215]	0	hSpCas9	negative selection	10211974
128705416	128705439	9	-	28162770	P31FUJ	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	1.4864613880183688	[81]	[269]	9	hSpCas9	negative selection	10211975
128705782	128705805	9	+	28162770	P31FUJ	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	0.6602825916691093	[62]	[116]	7	hSpCas9	negative selection	10211976
128706745	128706768	9	+	28162770	P31FUJ	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	0.9436954509514202	[145]	[329]	9	hSpCas9	negative selection	10211977
128706781	128706804	9	+	28162770	P31FUJ	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	0.37725127726960794	[75]	[115]	4	hSpCas9	negative selection	10211978
128707263	128707286	9	-	28162770	P31FUJ	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-1.1258870004978665	[64]	[34]	-7	hSpCas9	negative selection	10211979
128713139	128713162	9	-	28162770	P31FUJ	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	0.16649789151049643	[529]	[698]	1	hSpCas9	negative selection	10211980
128705362	128705385	9	+	28162770	TF1	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10381337
128713557	128713580	9	-	28162770	TF1	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	NaN	[NaN]	[190]	1	hSpCas9	negative selection	10381338
128715196	128715219	9	-	28162770	TF1	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	NaN	[NaN]	[92]	1	hSpCas9	negative selection	10381339
128702905	128702928	9	+	28162770	TF1	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	NaN	[NaN]	[223]	1	hSpCas9	negative selection	10381340
128705416	128705439	9	-	28162770	TF1	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10381341
128705782	128705805	9	+	28162770	TF1	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	NaN	[NaN]	[49]	1	hSpCas9	negative selection	10381342
128706745	128706768	9	+	28162770	TF1	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	NaN	[NaN]	[220]	1	hSpCas9	negative selection	10381343
128706781	128706804	9	+	28162770	TF1	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10381344
128707263	128707286	9	-	28162770	TF1	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10381345
128713139	128713162	9	-	28162770	TF1	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	NaN	[NaN]	[381]	1	hSpCas9	negative selection	10381346
128705362	128705385	9	+	28162770	SKM1	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	0.8036027871964966	[34]	[107]	7	hSpCas9	negative selection	10550703
128713557	128713580	9	-	28162770	SKM1	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-0.2781778920943357	[82]	[120]	-2	hSpCas9	negative selection	10550704
128715196	128715219	9	-	28162770	SKM1	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	0.35249603321013107	[34]	[78]	3	hSpCas9	negative selection	10550705
128702905	128702928	9	+	28162770	SKM1	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.06300979752580047	[64]	[109]	0	hSpCas9	negative selection	10550706
128705416	128705439	9	-	28162770	SKM1	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-0.2205510745122805	[28]	[43]	-2	hSpCas9	negative selection	10550707
128705782	128705805	9	+	28162770	SKM1	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	1.7994866787242647	[12]	[79]	9	hSpCas9	negative selection	10550708
128706745	128706768	9	+	28162770	SKM1	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	-1.3272370062724275	[43]	[30]	-7	hSpCas9	negative selection	10550709
128706781	128706804	9	+	28162770	SKM1	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	-1.5589672921882116	[14]	[8]	-8	hSpCas9	negative selection	10550710
128707263	128707286	9	-	28162770	SKM1	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-0.8220016980220057	[13]	[13]	-6	hSpCas9	negative selection	10550711
128713139	128713162	9	-	28162770	SKM1	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	-0.29784247636304917	[104]	[150]	-3	hSpCas9	negative selection	10550712
128705362	128705385	9	+	28162770	SKM1	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	0.8036027871964966	[34]	[107]	7	hSpCas9	negative selection	10720069
128713557	128713580	9	-	28162770	SKM1	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-0.2781778920943357	[82]	[120]	-2	hSpCas9	negative selection	10720070
128715196	128715219	9	-	28162770	SKM1	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	0.35249603321013107	[34]	[78]	3	hSpCas9	negative selection	10720071
128702905	128702928	9	+	28162770	SKM1	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.06300979752580047	[64]	[109]	0	hSpCas9	negative selection	10720072
128705416	128705439	9	-	28162770	SKM1	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-0.2205510745122805	[28]	[43]	-2	hSpCas9	negative selection	10720073
128705782	128705805	9	+	28162770	SKM1	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	1.7994866787242647	[12]	[79]	9	hSpCas9	negative selection	10720074
128706745	128706768	9	+	28162770	SKM1	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	-1.3272370062724275	[43]	[30]	-7	hSpCas9	negative selection	10720075
128706781	128706804	9	+	28162770	SKM1	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	-1.5589672921882116	[14]	[8]	-8	hSpCas9	negative selection	10720076
128707263	128707286	9	-	28162770	SKM1	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-0.8220016980220057	[13]	[13]	-6	hSpCas9	negative selection	10720077
128713139	128713162	9	-	28162770	SKM1	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	-0.29784247636304917	[104]	[150]	-3	hSpCas9	negative selection	10720078
128705362	128705385	9	+	28162770	PL21	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	0.015715043351892638	[174]	[76]	0	hSpCas9	negative selection	10889435
128713557	128713580	9	-	28162770	PL21	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-0.41251462010088435	[262]	[85]	-3	hSpCas9	negative selection	10889436
128715196	128715219	9	-	28162770	PL21	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	-0.787369441327483	[114]	[28]	-5	hSpCas9	negative selection	10889437
128702905	128702928	9	+	28162770	PL21	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	-0.32511664010756824	[212]	[73]	-2	hSpCas9	negative selection	10889438
128705416	128705439	9	-	28162770	PL21	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-0.9487237714251623	[101]	[22]	-6	hSpCas9	negative selection	10889439
128705782	128705805	9	+	28162770	PL21	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	-1.182330022333093	[72]	[13]	-7	hSpCas9	negative selection	10889440
128706745	128706768	9	+	28162770	PL21	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	1.6777185798368768	[78]	[109]	9	hSpCas9	negative selection	10889441
128706781	128706804	9	+	28162770	PL21	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	-2.79986038551068	[63]	[3]	-9	hSpCas9	negative selection	10889442
128707263	128707286	9	-	28162770	PL21	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-0.5703785393879124	[57]	[16]	-4	hSpCas9	negative selection	10889443
128713139	128713162	9	-	28162770	PL21	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	0.6405052937141884	[366]	[248]	5	hSpCas9	negative selection	10889444
128705362	128705385	9	+	28162770	P31FUJ	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	-0.4632860381043744	[148]	[126]	-4	hSpCas9	negative selection	11058801
128713557	128713580	9	-	28162770	P31FUJ	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-0.39326687660762477	[360]	[322]	-4	hSpCas9	negative selection	11058802
128715196	128715219	9	-	28162770	P31FUJ	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	0.42220779383503404	[133]	[210]	5	hSpCas9	negative selection	11058803
128702905	128702928	9	+	28162770	P31FUJ	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.030232201419415294	[179]	[215]	0	hSpCas9	negative selection	11058804
128705416	128705439	9	-	28162770	P31FUJ	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	1.4864613880183688	[81]	[269]	9	hSpCas9	negative selection	11058805
128705782	128705805	9	+	28162770	P31FUJ	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	0.6602825916691093	[62]	[116]	7	hSpCas9	negative selection	11058806
128706745	128706768	9	+	28162770	P31FUJ	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	0.9436954509514202	[145]	[329]	9	hSpCas9	negative selection	11058807
128706781	128706804	9	+	28162770	P31FUJ	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	0.37725127726960794	[75]	[115]	4	hSpCas9	negative selection	11058808
128707263	128707286	9	-	28162770	P31FUJ	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-1.1258870004978665	[64]	[34]	-7	hSpCas9	negative selection	11058809
128713139	128713162	9	-	28162770	P31FUJ	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	0.16649789151049643	[529]	[698]	1	hSpCas9	negative selection	11058810
128705362	128705385	9	+	28162770	OCIAML5	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	-0.3082427649363273	[82]	[120]	-2	hSpCas9	negative selection	11228167
128713557	128713580	9	-	28162770	OCIAML5	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	0.21489925300480783	[220]	[462]	1	hSpCas9	negative selection	11228168
128715196	128715219	9	-	28162770	OCIAML5	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	1.4402160622748406	[58]	[288]	9	hSpCas9	negative selection	11228169
128702905	128702928	9	+	28162770	OCIAML5	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.27176201598886146	[105]	[230]	2	hSpCas9	negative selection	11228170
128705416	128705439	9	-	28162770	OCIAML5	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-0.2926391622499782	[37]	[55]	-2	hSpCas9	negative selection	11228171
128705782	128705805	9	+	28162770	OCIAML5	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	1.0654712689440302	[26]	[101]	8	hSpCas9	negative selection	11228172
128706745	128706768	9	+	28162770	OCIAML5	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	1.336063025955906	[69]	[318]	9	hSpCas9	negative selection	11228173
128706781	128706804	9	+	28162770	OCIAML5	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	-0.26087211643132635	[76]	[115]	-2	hSpCas9	negative selection	11228174
128707263	128707286	9	-	28162770	OCIAML5	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-1.4859386720660994	[44]	[28]	-7	hSpCas9	negative selection	11228175
128713139	128713162	9	-	28162770	OCIAML5	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	0.44216979015431734	[262]	[644]	4	hSpCas9	negative selection	11228176
128705362	128705385	9	+	28162770	EOL1	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	-1.4607423843142573	[255]	[48]	-7	hSpCas9	negative selection	11397533
128713557	128713580	9	-	28162770	EOL1	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-0.5465948295934595	[401]	[144]	-4	hSpCas9	negative selection	11397534
128715196	128715219	9	-	28162770	EOL1	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	-0.08794317261266243	[231]	[114]	0	hSpCas9	negative selection	11397535
128702905	128702928	9	+	28162770	EOL1	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.5424349107325519	[360]	[276]	5	hSpCas9	negative selection	11397536
128705416	128705439	9	-	28162770	EOL1	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-0.6604147291506217	[161]	[53]	-5	hSpCas9	negative selection	11397537
128705782	128705805	9	+	28162770	EOL1	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	-0.2978446497659133	[139]	[59]	-2	hSpCas9	negative selection	11397538
128706745	128706768	9	+	28162770	EOL1	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	-1.2978446497659133	[139]	[29]	-7	hSpCas9	negative selection	11397539
128706781	128706804	9	+	28162770	EOL1	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	-1.0437433687021271	[89]	[22]	-6	hSpCas9	negative selection	11397540
128707263	128707286	9	-	28162770	EOL1	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-1.1507403557337024	[58]	[13]	-6	hSpCas9	negative selection	11397541
128713139	128713162	9	-	28162770	EOL1	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	-1.0268720479844038	[583]	[150]	-6	hSpCas9	negative selection	11397542
128705362	128705385	9	+	28162770	MOLM13	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	0.8806277647338345	[156]	[208]	6	hSpCas9	negative selection	11566899
128713557	128713580	9	-	28162770	MOLM13	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-1.05658135882021	[396]	[137]	-5	hSpCas9	negative selection	11566900
128715196	128715219	9	-	28162770	MOLM13	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	0.8852078220746609	[157]	[210]	6	hSpCas9	negative selection	11566901
128702905	128702928	9	+	28162770	MOLM13	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.1647656880952737	[342]	[277]	1	hSpCas9	negative selection	11566902
128705416	128705439	9	-	28162770	MOLM13	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	0.10689172197862407	[130]	[101]	0	hSpCas9	negative selection	11566903
128705782	128705805	9	+	28162770	MOLM13	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	1.3909273997296947	[76]	[145]	9	hSpCas9	negative selection	11566904
128706745	128706768	9	+	28162770	MOLM13	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	0.9084619729305601	[125]	[170]	7	hSpCas9	negative selection	11566905
128706781	128706804	9	+	28162770	MOLM13	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	-1.688615104135412	[106]	[23]	-7	hSpCas9	negative selection	11566906
128707263	128707286	9	-	28162770	MOLM13	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-3.2325503365965136	[51]	[3]	-8	hSpCas9	negative selection	11566907
128713139	128713162	9	-	28162770	MOLM13	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	-1.1946940162990514	[629]	[198]	-6	hSpCas9	negative selection	11566908
128705362	128705385	9	+	28162770	HEL	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	-0.02563967690843677	[177]	[111]	0	hSpCas9	negative selection	11736265
128713557	128713580	9	-	28162770	HEL	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	0.5358236280838451	[265]	[246]	4	hSpCas9	negative selection	11736266
128715196	128715219	9	-	28162770	HEL	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	-0.39790315249698904	[143]	[69]	-3	hSpCas9	negative selection	11736267
128702905	128702928	9	+	28162770	HEL	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	1.780242355750292	[259]	[571]	9	hSpCas9	negative selection	11736268
128705416	128705439	9	-	28162770	HEL	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-1.1593217903877342	[135]	[38]	-6	hSpCas9	negative selection	11736269
128705782	128705805	9	+	28162770	HEL	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	0.832563390880374	[63]	[72]	7	hSpCas9	negative selection	11736270
128706745	128706768	9	+	28162770	HEL	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	-0.32601023401520335	[136]	[69]	-2	hSpCas9	negative selection	11736271
128706781	128706804	9	+	28162770	HEL	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	-1.5041025563289139	[61]	[13]	-7	hSpCas9	negative selection	11736272
128707263	128707286	9	-	28162770	HEL	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-4.486544184944609	[69]	[1]	-9	hSpCas9	negative selection	11736273
128713139	128713162	9	-	28162770	HEL	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	0.00255436154418176	[465]	[298]	0	hSpCas9	negative selection	11736274
128705362	128705385	9	+	28162770	MV411	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	-0.18552185649333103	[134]	[99]	-1	hSpCas9	negative selection	11905631
128713557	128713580	9	-	28162770	MV411	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-0.8114561382707932	[249]	[119]	-5	hSpCas9	negative selection	11905632
128715196	128715219	9	-	28162770	MV411	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	0.654861865951744	[94]	[125]	6	hSpCas9	negative selection	11905633
128702905	128702928	9	+	28162770	MV411	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.35337099553184037	[209]	[225]	3	hSpCas9	negative selection	11905634
128705416	128705439	9	-	28162770	MV411	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	0.35549729664022833	[89]	[96]	3	hSpCas9	negative selection	11905635
128705782	128705805	9	+	28162770	MV411	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	-0.868039666637161	[64]	[29]	-5	hSpCas9	negative selection	11905636
128706745	128706768	9	+	28162770	MV411	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	1.3959600754928634	[82]	[183]	9	hSpCas9	negative selection	11905637
128706781	128706804	9	+	28162770	MV411	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	-1.0103602066848716	[54]	[22]	-6	hSpCas9	negative selection	11905638
128707263	128707286	9	-	28162770	MV411	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-0.9452075271596205	[47]	[20]	-6	hSpCas9	negative selection	11905639
128713139	128713162	9	-	28162770	MV411	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	-0.40311329156595777	[404]	[257]	-3	hSpCas9	negative selection	11905640
128705362	128705385	9	+	28162770	MONOMAC1	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	-0.05953332330961869	[89]	[98]	0	hSpCas9	negative selection	12074997
128713557	128713580	9	-	28162770	MONOMAC1	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-1.2191758243288022	[196]	[96]	-7	hSpCas9	negative selection	12074998
128715196	128715219	9	-	28162770	MONOMAC1	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	0.17883005493861232	[83]	[108]	1	hSpCas9	negative selection	12074999
128702905	128702928	9	+	28162770	MONOMAC1	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.5587263425607786	[121]	[205]	5	hSpCas9	negative selection	12075000
128705416	128705439	9	-	28162770	MONOMAC1	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	1.4231150821239025	[53]	[165]	9	hSpCas9	negative selection	12075001
128705782	128705805	9	+	28162770	MONOMAC1	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	0.7590198053528494	[49]	[96]	7	hSpCas9	negative selection	12075002
128706745	128706768	9	+	28162770	MONOMAC1	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	-0.3270973876239267	[57]	[52]	-3	hSpCas9	negative selection	12075003
128706781	128706804	9	+	28162770	MONOMAC1	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	-2.071505964975695	[43]	[11]	-9	hSpCas9	negative selection	12075004
128707263	128707286	9	-	28162770	MONOMAC1	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	-0.027111845617241226	[23]	[26]	0	hSpCas9	negative selection	12075005
128713139	128713162	9	-	28162770	MONOMAC1	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	-0.05454991579536328	[288]	[318]	0	hSpCas9	negative selection	12075006
128705362	128705385	9	+	28162770	OCIAML2	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	-0.36629316542742574	[19]	[85]	-3	hSpCas9	negative selection	12244363
128713557	128713580	9	-	28162770	OCIAML2	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-0.051404528999883986	[42]	[229]	0	hSpCas9	negative selection	12244364
128715196	128715219	9	-	28162770	OCIAML2	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	0.5680506429218986	[22]	[188]	5	hSpCas9	negative selection	12244365
128702905	128702928	9	+	28162770	OCIAML2	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	0.0699385561205415	[43]	[255]	0	hSpCas9	negative selection	12244366
128705416	128705439	9	-	28162770	OCIAML2	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	-0.40454063478438873	[15]	[66]	-3	hSpCas9	negative selection	12244367
128705782	128705805	9	+	28162770	OCIAML2	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	1.2298098928989312	[10]	[142]	9	hSpCas9	negative selection	12244368
128706745	128706768	9	+	28162770	OCIAML2	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	-0.6366397766810904	[22]	[81]	-5	hSpCas9	negative selection	12244369
128706781	128706804	9	+	28162770	OCIAML2	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	-2.108059745857453	[13]	[17]	-8	hSpCas9	negative selection	12244370
128707263	128707286	9	-	28162770	OCIAML2	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	0.6586531917028051	[7]	[69]	6	hSpCas9	negative selection	12244371
128713139	128713162	9	-	28162770	OCIAML2	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	-0.5751604087134679	[92]	[345]	-4	hSpCas9	negative selection	12244372
128705362	128705385	9	+	28162770	OCIAML3	viability	GAAAGAGCTGAAGATCAAGGAGG	PKN3	ENSG00000160447	0.5835305452280243	[41]	[189]	5	hSpCas9	negative selection	12413729
128713557	128713580	9	-	28162770	OCIAML3	viability	GAAGTCCTCAAGTCTCAGGAAGG	PKN3	ENSG00000160447	-0.23036929355196345	[74]	[192]	-2	hSpCas9	negative selection	12413730
128715196	128715219	9	-	28162770	OCIAML3	viability	GGCCCAGCACAGCTAAGCAGCGG	PKN3	ENSG00000160447	0.13779624872626428	[27]	[92]	1	hSpCas9	negative selection	12413731
128702905	128702928	9	+	28162770	OCIAML3	viability	GGAGCGGCGCCATGGAGGAGGGG	PKN3	ENSG00000160447	1.4595078690028385	[42]	[356]	9	hSpCas9	negative selection	12413732
128705416	128705439	9	-	28162770	OCIAML3	viability	GCACATGGCCCAAGTGGCGGCGG	PKN3	ENSG00000160447	0.19026366862039978	[26]	[92]	1	hSpCas9	negative selection	12413733
128705782	128705805	9	+	28162770	OCIAML3	viability	GGCACCTAGAGGCTCTCCGGAGG	PKN3	ENSG00000160447	-0.17316451936411337	[30]	[82]	-1	hSpCas9	negative selection	12413734
128706745	128706768	9	+	28162770	OCIAML3	viability	GCTGCGGGACAGCCAGCTGAAGG	PKN3	ENSG00000160447	0.11294538477560345	[33]	[110]	1	hSpCas9	negative selection	12413735
128706781	128706804	9	+	28162770	OCIAML3	viability	GATGAAGATCAGCAGCCTGGAGG	PKN3	ENSG00000160447	0.5270077606372027	[19]	[86]	5	hSpCas9	negative selection	12413736
128707263	128707286	9	-	28162770	OCIAML3	viability	GCTGCTCCAAGGCCAGGCGCAGG	PKN3	ENSG00000160447	1.8359802004206522	[8]	[96]	9	hSpCas9	negative selection	12413737
128713139	128713162	9	-	28162770	OCIAML3	viability	GGTCCGAAGCCAGCCCTCGGAGG	PKN3	ENSG00000160447	-0.4588480570425274	[111]	[245]	-4	hSpCas9	negative selection	12413738