Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5324
• Symbol: PLAG1
• Description: PLAG1 zinc finger

DataSource: http://genomecrispr.dkfz.de/#!/results/PLAG1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
56167001	56167024	8	-	26472758	Jiyoye	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.32113555043918196	[379]	[357]	2	hSpCas9	negative selection	121703
56167112	56167135	8	-	26472758	Jiyoye	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	0.13334157481955566	[294]	[243]	1	hSpCas9	negative selection	121704
56166926	56166949	8	+	26472758	Jiyoye	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.8307748942881412	[125]	[168]	6	hSpCas9	negative selection	121705
56166248	56166271	8	+	26472758	Jiyoye	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	-0.0078621177729703	[35]	[26]	0	hSpCas9	negative selection	121706
56167293	56167316	8	+	26472758	Jiyoye	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-0.1954891209487416	[204]	[134]	-1	hSpCas9	negative selection	121707
56167225	56167248	8	-	26472758	Jiyoye	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	0.27111383192984484	[99]	[90]	2	hSpCas9	negative selection	121708
56167169	56167192	8	+	26472758	Jiyoye	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.7883754276119335	[70]	[30]	-5	hSpCas9	negative selection	121709
56167130	56167153	8	-	26472758	Jiyoye	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.009091015508226774	[140]	[106]	0	hSpCas9	negative selection	121710
56167085	56167108	8	+	26472758	Jiyoye	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	-0.1752932637267246	[288]	[192]	-1	hSpCas9	negative selection	121711
56167210	56167233	8	-	26472758	Jiyoye	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	-1.2094959789426207	[137]	[44]	-7	hSpCas9	negative selection	121712
56167001	56167024	8	-	26472758	KBM7	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.4779867952385739	[1265,743]	[702,590]	5	hSpCas9	negative selection	312821
56167112	56167135	8	-	26472758	KBM7	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	0.8070645898517265	[707,912]	[930,452]	8	hSpCas9	negative selection	312822
56166926	56166949	8	+	26472758	KBM7	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	-0.07427800017073416	[967,571]	[326,344]	0	hSpCas9	negative selection	312823
56166248	56166271	8	+	26472758	KBM7	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	0.20662165052347214	[107,125]	[105,26]	2	hSpCas9	negative selection	312824
56167293	56167316	8	+	26472758	KBM7	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	0.55020933688439	[525,640]	[440,377]	6	hSpCas9	negative selection	312825
56167225	56167248	8	-	26472758	KBM7	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	-0.10282379265013875	[436,350]	[153,186]	-1	hSpCas9	negative selection	312826
56167169	56167192	8	+	26472758	KBM7	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.23359603103149346	[314,349]	[146,122]	-2	hSpCas9	negative selection	312827
56167130	56167153	8	-	26472758	KBM7	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.3329293038350958	[709,488]	[245,197]	-3	hSpCas9	negative selection	312828
56167085	56167108	8	+	26472758	KBM7	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	-0.23653894016757948	[1016,1115]	[453,407]	-2	hSpCas9	negative selection	312829
56167210	56167233	8	-	26472758	KBM7	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	-0.5008532615950628	[422,606]	[182,167]	-4	hSpCas9	negative selection	312830
56167001	56167024	8	-	26472758	Raji	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.01992069412326014	[577]	[135]	0	hSpCas9	negative selection	503939
56167112	56167135	8	-	26472758	Raji	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	0.8834186942183979	[305]	[130]	7	hSpCas9	negative selection	503940
56166926	56166949	8	+	26472758	Raji	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.7725163847787389	[279]	[110]	7	hSpCas9	negative selection	503941
56166248	56166271	8	+	26472758	Raji	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	0.1898456955655723	[67]	[17]	1	hSpCas9	negative selection	503942
56167293	56167316	8	+	26472758	Raji	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-0.003510056138624318	[418]	[96]	0	hSpCas9	negative selection	503943
56167225	56167248	8	-	26472758	Raji	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	-0.6345483116859563	[193]	[28]	-5	hSpCas9	negative selection	503944
56167169	56167192	8	+	26472758	Raji	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	0.44745897697122133	[157]	[49]	4	hSpCas9	negative selection	503945
56167130	56167153	8	-	26472758	Raji	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.3265129911565601	[307]	[56]	-3	hSpCas9	negative selection	503946
56167085	56167108	8	+	26472758	Raji	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	-0.19433133862425422	[566]	[114]	-2	hSpCas9	negative selection	503947
56167210	56167233	8	-	26472758	Raji	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	-0.7480656748850496	[426]	[58]	-5	hSpCas9	negative selection	503948
56167001	56167024	8	-	26472758	K562	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.9024308834958408	[859]	[1356]	7	hSpCas9	negative selection	695057
56167112	56167135	8	-	26472758	K562	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	0.5413214266331741	[848]	[1042]	4	hSpCas9	negative selection	695058
56166926	56166949	8	+	26472758	K562	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.06608148640793432	[601]	[531]	0	hSpCas9	negative selection	695059
56166248	56166271	8	+	26472758	K562	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	-0.8472117477991215	[129]	[60]	-5	hSpCas9	negative selection	695060
56167293	56167316	8	+	26472758	K562	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-0.8457790813051314	[725]	[340]	-5	hSpCas9	negative selection	695061
56167225	56167248	8	-	26472758	K562	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	-1.1735012801455182	[333]	[124]	-6	hSpCas9	negative selection	695062
56167169	56167192	8	+	26472758	K562	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.03526691871751075	[243]	[200]	0	hSpCas9	negative selection	695063
56167130	56167153	8	-	26472758	K562	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.6896429475441667	[602]	[820]	5	hSpCas9	negative selection	695064
56167085	56167108	8	+	26472758	K562	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	-0.6397005602834134	[824]	[446]	-4	hSpCas9	negative selection	695065
56167210	56167233	8	-	26472758	K562	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	0.654472819431035	[434]	[577]	5	hSpCas9	negative selection	695066
56166252	56166275	8	+	26627737	DLD1	viability	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	0.7154774198457488	[212]	[109,73,137]	7	hSpCas9	negative selection	839789
56166649	56166672	8	-	26627737	DLD1	viability	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	0.07090775745872568	[315]	[90,146,78]	0	hSpCas9	negative selection	839790
56167148	56167171	8	+	26627737	DLD1	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.5185216922767342	[761]	[419,322,287]	5	hSpCas9	negative selection	839791
56167151	56167174	8	-	26627737	DLD1	viability	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.10317758536348154	[692]	[182,279,152]	-1	hSpCas9	negative selection	839792
56168243	56168266	8	+	26627737	DLD1	viability	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	0.038652081877500244	[750]	[265,300,169]	0	hSpCas9	negative selection	839793
56166252	56166275	8	+	26627737	GBM cells	viability after 5 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	-0.4387815358599932	[229]	[90,90]	-6	hSpCas9	negative selection	922104
56166649	56166672	8	-	26627737	GBM cells	viability after 5 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-1.2023694609514963	[235]	[60,48]	-9	hSpCas9	negative selection	922105
56167148	56167171	8	+	26627737	GBM cells	viability after 5 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.08959743649479535	[551]	[318,310]	1	hSpCas9	negative selection	922106
56167151	56167174	8	-	26627737	GBM cells	viability after 5 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.31612902746989935	[330]	[233,207]	5	hSpCas9	negative selection	922107
56168243	56168266	8	+	26627737	GBM cells	viability after 5 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	-0.4453022872034615	[423]	[129,203]	-6	hSpCas9	negative selection	922108
56166252	56166275	8	+	26627737	GBM cells	viability after 13 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	-0.33896774026417975	[229]	[112,86]	-4	hSpCas9	negative selection	1004419
56166649	56166672	8	-	26627737	GBM cells	viability after 13 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-1.4616092628597377	[235]	[67,28]	-9	hSpCas9	negative selection	1004420
56167148	56167171	8	+	26627737	GBM cells	viability after 13 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.266668838637395	[551]	[431,301]	3	hSpCas9	negative selection	1004421
56167151	56167174	8	-	26627737	GBM cells	viability after 13 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.5756037054943113	[330]	[324,220]	7	hSpCas9	negative selection	1004422
56168243	56168266	8	+	26627737	GBM cells	viability after 13 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	-0.7738818243820538	[423]	[192,86]	-7	hSpCas9	negative selection	1004423
56166252	56166275	8	+	26627737	GBM cells	viability after 21 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	0.004625373946471667	[229]	[116,132]	0	hSpCas9	negative selection	1086734
56166649	56166672	8	-	26627737	GBM cells	viability after 21 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-1.0968556017004785	[235]	[72,47]	-7	hSpCas9	negative selection	1086735
56167148	56167171	8	+	26627737	GBM cells	viability after 21 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.248297551002586	[551]	[362,349]	2	hSpCas9	negative selection	1086736
56167151	56167174	8	-	26627737	GBM cells	viability after 21 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.14898709918220587	[330]	[201,196]	1	hSpCas9	negative selection	1086737
56168243	56168266	8	+	26627737	GBM cells	viability after 21 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	-0.8940080322489034	[423]	[124,122]	-6	hSpCas9	negative selection	1086738
56166252	56166275	8	+	26627737	RPE1	viability after 9 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	1.5163873772944485	[135]	[85,167]	8	hSpCas9	negative selection	1169049
56166649	56166672	8	-	26627737	RPE1	viability after 9 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.3999834204815811	[654]	[171,133]	-3	hSpCas9	negative selection	1169050
56167148	56167171	8	+	26627737	RPE1	viability after 9 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	1.3289441778816689	[815]	[591,705]	7	hSpCas9	negative selection	1169051
56167151	56167174	8	-	26627737	RPE1	viability after 9 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.2623265776897552	[1560]	[351,478]	-2	hSpCas9	negative selection	1169052
56168243	56168266	8	+	26627737	RPE1	viability after 9 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	-1.217473386554353	[1513]	[181,231]	-7	hSpCas9	negative selection	1169053
56166252	56166275	8	+	26627737	RPE1	viability after 12 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	1.9153797453779169	[135]	[131,143]	8	hSpCas9	negative selection	1251364
56166649	56166672	8	-	26627737	RPE1	viability after 12 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.3793739913408939	[654]	[110,160]	-3	hSpCas9	negative selection	1251365
56167148	56167171	8	+	26627737	RPE1	viability after 12 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	1.5148238717144251	[815]	[557,698]	8	hSpCas9	negative selection	1251366
56167151	56167174	8	-	26627737	RPE1	viability after 12 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.5106495690353507	[1560]	[238,352]	-4	hSpCas9	negative selection	1251367
56168243	56168266	8	+	26627737	RPE1	viability after 12 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	-1.3993791232849218	[1513]	[160,146]	-7	hSpCas9	negative selection	1251368
56166252	56166275	8	+	26627737	RPE1	viability after 15 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	1.2630185633755864	[135]	[129,55]	7	hSpCas9	negative selection	1333679
56166649	56166672	8	-	26627737	RPE1	viability after 15 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.7358673498910946	[654]	[124,97]	-5	hSpCas9	negative selection	1333680
56167148	56167171	8	+	26627737	RPE1	viability after 15 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	1.7023446307969474	[815]	[543,950]	8	hSpCas9	negative selection	1333681
56167151	56167174	8	-	26627737	RPE1	viability after 15 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.4632932190613348	[1560]	[247,389]	-3	hSpCas9	negative selection	1333682
56168243	56168266	8	+	26627737	RPE1	viability after 15 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	-0.7634249194420709	[1513]	[319,186]	-5	hSpCas9	negative selection	1333683
56166252	56166275	8	+	26627737	RPE1	viability after 18 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	1.6593019941610245	[135]	[142,86]	8	hSpCas9	negative selection	1415994
56166649	56166672	8	-	26627737	RPE1	viability after 18 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.4978214727416441	[654]	[144,103]	-3	hSpCas9	negative selection	1415995
56167148	56167171	8	+	26627737	RPE1	viability after 18 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	2.0579388202108544	[815]	[725,1120]	8	hSpCas9	negative selection	1415996
56167151	56167174	8	-	26627737	RPE1	viability after 18 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.2315466705809286	[1560]	[352,364]	-1	hSpCas9	negative selection	1415997
56168243	56168266	8	+	26627737	RPE1	viability after 18 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	-1.0285752717698715	[1513]	[193,206]	-6	hSpCas9	negative selection	1415998
56166252	56166275	8	+	26627737	HeLa	viability after 8 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	-1.001942871091897	[377]	[149,53,58]	-7	hSpCas9	negative selection	1498309
56166649	56166672	8	-	26627737	HeLa	viability after 8 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.1428344333373085	[290]	[128,129,89]	-1	hSpCas9	negative selection	1498310
56167148	56167171	8	+	26627737	HeLa	viability after 8 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.1587965242851952	[798]	[462,405,316]	1	hSpCas9	negative selection	1498311
56167151	56167174	8	-	26627737	HeLa	viability after 8 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.12862704221733556	[647]	[455,158,339]	1	hSpCas9	negative selection	1498312
56168243	56168266	8	+	26627737	HeLa	viability after 8 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	0.08667345728847436	[554]	[363,186,242]	0	hSpCas9	negative selection	1498313
56166252	56166275	8	+	26627737	HeLa	viability after 12 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	-0.7753381211679887	[377]	[88,135,43]	-6	hSpCas9	negative selection	1580624
56166649	56166672	8	-	26627737	HeLa	viability after 12 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.1003903322318701	[290]	[265,64,14]	-1	hSpCas9	negative selection	1580625
56167148	56167171	8	+	26627737	HeLa	viability after 12 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.38694469625661077	[798]	[583,268,463]	3	hSpCas9	negative selection	1580626
56167151	56167174	8	-	26627737	HeLa	viability after 12 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.36138242384741864	[647]	[203,172,251]	-3	hSpCas9	negative selection	1580627
56168243	56168266	8	+	26627737	HeLa	viability after 12 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	-0.3344656113756633	[554]	[164,98,289]	-3	hSpCas9	negative selection	1580628
56166252	56166275	8	+	26627737	HeLa	viability after 15 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	-1.4311176737182068	[377]	[28,43,101]	-8	hSpCas9	negative selection	1662939
56166649	56166672	8	-	26627737	HeLa	viability after 15 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.38762253631286037	[290]	[156,32,79]	-3	hSpCas9	negative selection	1662940
56167148	56167171	8	+	26627737	HeLa	viability after 15 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.24138218578727755	[798]	[242,471,444]	2	hSpCas9	negative selection	1662941
56167151	56167174	8	-	26627737	HeLa	viability after 15 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.0978960610777363	[647]	[122,274,464]	0	hSpCas9	negative selection	1662942
56168243	56168266	8	+	26627737	HeLa	viability after 15 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	0.048837305103056006	[554]	[156,107,453]	0	hSpCas9	negative selection	1662943
56166252	56166275	8	+	26627737	HeLa	viability after 18 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	-1.3927028094622032	[377]	[21,36,101]	-8	hSpCas9	negative selection	1745254
56166649	56166672	8	-	26627737	HeLa	viability after 18 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.3017851742159764	[290]	[117,24,79]	-3	hSpCas9	negative selection	1745255
56167148	56167171	8	+	26627737	HeLa	viability after 18 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.22409736226239874	[798]	[161,380,444]	2	hSpCas9	negative selection	1745256
56167151	56167174	8	-	26627737	HeLa	viability after 18 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.10550853054967002	[647]	[81,231,464]	0	hSpCas9	negative selection	1745257
56168243	56168266	8	+	26627737	HeLa	viability after 18 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	0.04730267936366245	[554]	[101,92,453]	0	hSpCas9	negative selection	1745258
56166252	56166275	8	+	26627737	HCT116	viability after 6 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	0.9638453055009113	[465]	[265,74]	5	hSpCas9	negative selection	1827569
56166649	56166672	8	-	26627737	HCT116	viability after 6 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	0.7927986677965804	[632]	[47,240]	4	hSpCas9	negative selection	1827570
56167148	56167171	8	+	26627737	HCT116	viability after 6 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	-0.7153213969305153	[914]	[153,50]	-4	hSpCas9	negative selection	1827571
56167151	56167174	8	-	26627737	HCT116	viability after 6 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.7365168922070914	[575]	[117,168]	4	hSpCas9	negative selection	1827572
56168243	56168266	8	+	26627737	HCT116	viability after 6 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	0.5352129179242654	[459]	[263,16]	3	hSpCas9	negative selection	1827573
56166252	56166275	8	+	26627737	HCT116	viability after 8 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	-1.0336044286818682	[306]	[81,91,73]	-8	hSpCas9	negative selection	1909884
56166649	56166672	8	-	26627737	HCT116	viability after 8 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-1.2838793376919857	[491]	[143,111,78]	-9	hSpCas9	negative selection	1909885
56167148	56167171	8	+	26627737	HCT116	viability after 8 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.24465684031230894	[530]	[489,323,229]	2	hSpCas9	negative selection	1909886
56167151	56167174	8	-	26627737	HCT116	viability after 8 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.17520576283929123	[541]	[175,274,339]	-2	hSpCas9	negative selection	1909887
56168243	56168266	8	+	26627737	HCT116	viability after 8 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	1.3609108455068655	[154]	[263,182,211]	9	hSpCas9	negative selection	1909888
56166252	56166275	8	+	26627737	HCT116	viability after 9 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	0.5678931687478349	[465]	[141,217]	4	hSpCas9	negative selection	1992199
56166649	56166672	8	-	26627737	HCT116	viability after 9 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-1.4510743338673242	[632]	[115,18]	-7	hSpCas9	negative selection	1992200
56167148	56167171	8	+	26627737	HCT116	viability after 9 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	1.0126475243141053	[914]	[378,582]	7	hSpCas9	negative selection	1992201
56167151	56167174	8	-	26627737	HCT116	viability after 9 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	1.5161586460432477	[575]	[454,427]	8	hSpCas9	negative selection	1992202
56168243	56168266	8	+	26627737	HCT116	viability after 9 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	1.4252704706596488	[459]	[373,294]	8	hSpCas9	negative selection	1992203
56166252	56166275	8	+	26627737	HCT116	viability after 12 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	-0.11150848895747636	[306]	[73,205,175]	-1	hSpCas9	negative selection	2074514
56166649	56166672	8	-	26627737	HCT116	viability after 12 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-1.1512620448071336	[491]	[54,172,127]	-8	hSpCas9	negative selection	2074515
56167148	56167171	8	+	26627737	HCT116	viability after 12 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.32074770222491533	[530]	[372,329,339]	3	hSpCas9	negative selection	2074516
56167151	56167174	8	-	26627737	HCT116	viability after 12 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.45096007496964463	[541]	[133,263,234]	-5	hSpCas9	negative selection	2074517
56168243	56168266	8	+	26627737	HCT116	viability after 12 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	1.5012157337955139	[154]	[252,238,197]	9	hSpCas9	negative selection	2074518
56166252	56166275	8	+	26627737	HCT116	viability after 15 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	-0.024636192047572537	[306]	[60,163,279]	0	hSpCas9	negative selection	2156829
56166649	56166672	8	-	26627737	HCT116	viability after 15 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-1.2362489340023717	[491]	[71,163,117]	-8	hSpCas9	negative selection	2156830
56167148	56167171	8	+	26627737	HCT116	viability after 15 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	-0.026648376665251994	[530]	[324,340,235]	0	hSpCas9	negative selection	2156831
56167151	56167174	8	-	26627737	HCT116	viability after 15 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.32965601606065276	[541]	[345,159,248]	-3	hSpCas9	negative selection	2156832
56168243	56168266	8	+	26627737	HCT116	viability after 15 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	1.4010074352226898	[154]	[303,205,203]	9	hSpCas9	negative selection	2156833
56166252	56166275	8	+	26627737	HCT116	viability after 18 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	0.03220865880591465	[306]	[73,134,251]	0	hSpCas9	negative selection	2239144
56166649	56166672	8	-	26627737	HCT116	viability after 18 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-1.7295879126482654	[491]	[29,115,65]	-8	hSpCas9	negative selection	2239145
56167148	56167171	8	+	26627737	HCT116	viability after 18 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	-0.37747661200784405	[530]	[219,109,271]	-3	hSpCas9	negative selection	2239146
56167151	56167174	8	-	26627737	HCT116	viability after 18 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.5070567432140882	[541]	[188,157,208]	-4	hSpCas9	negative selection	2239147
56168243	56168266	8	+	26627737	HCT116	viability after 18 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	1.9398934018723426	[154]	[379,176,313]	9	hSpCas9	negative selection	2239148
56167286	56167309	8	-	24336569	HL60	viability	AAGTGGTGACCTCACCTGTAAGG	PLAG1	ENSG00000181690	1.7037605520633616	[121]	[840]	9	hSpCas9	negative selection	2284473
56167293	56167316	8	+	24336569	HL60	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-1.0379312060741828	[456]	[470]	-7	hSpCas9	negative selection	2284474
56167302	56167325	8	+	24336569	HL60	viability	ACCACTTGTTGCGGCATGCAAGG	PLAG1	ENSG00000181690	0.624212265878343	[549]	[1793]	5	hSpCas9	negative selection	2284475
56167325	56167348	8	-	24336569	HL60	viability	GCTTGGATTTAAACGTCACTTGG	PLAG1	ENSG00000181690	-0.4464438933530035	[641]	[996]	-4	hSpCas9	negative selection	2284476
56167342	56167365	8	-	24336569	HL60	viability	AAGAACTACAATACCAAGCTTGG	PLAG1	ENSG00000181690	-0.4965015999077402	[499]	[749]	-4	hSpCas9	negative selection	2284477
56167366	56167389	8	-	24336569	HL60	viability	ACGTTTAAGTGCGAAGAATGTGG	PLAG1	ENSG00000181690	-0.3304654474237997	[797]	[1342]	-3	hSpCas9	negative selection	2284478
56167378	56167401	8	+	24336569	HL60	viability	CACTTAAACGTCTCTTTGTTAGG	PLAG1	ENSG00000181690	0.32737205948163106	[611]	[1624]	3	hSpCas9	negative selection	2284479
56167391	56167414	8	+	24336569	HL60	viability	CTTTGTTAGGGTCGTGTGTATGG	PLAG1	ENSG00000181690	0.060938222533877595	[587]	[1297]	0	hSpCas9	negative selection	2284480
56167418	56167441	8	+	24336569	HL60	viability	GATTCTTCAGATGATCTTTCCGG	PLAG1	ENSG00000181690	0.9691619724410716	[587]	[2435]	7	hSpCas9	negative selection	2284481
56167451	56167474	8	+	24336569	HL60	viability	TCTCACAATAATTACACTTGTGG	PLAG1	ENSG00000181690	0.3494571781082033	[891]	[2404]	3	hSpCas9	negative selection	2284482
56167286	56167309	8	-	24336569	KBM7	viability	AAGTGGTGACCTCACCTGTAAGG	PLAG1	ENSG00000181690	1.046454337971993	[190]	[1075]	8	hSpCas9	negative selection	2351650
56167293	56167316	8	+	24336569	KBM7	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-1.8082895334383693	[442]	[344]	-8	hSpCas9	negative selection	2351651
56167302	56167325	8	+	24336569	KBM7	viability	ACCACTTGTTGCGGCATGCAAGG	PLAG1	ENSG00000181690	0.8518147132818308	[541]	[2667]	7	hSpCas9	negative selection	2351652
56167325	56167348	8	-	24336569	KBM7	viability	GCTTGGATTTAAACGTCACTTGG	PLAG1	ENSG00000181690	0.9678403218082928	[235]	[1258]	8	hSpCas9	negative selection	2351653
56167342	56167365	8	-	24336569	KBM7	viability	AAGAACTACAATACCAAGCTTGG	PLAG1	ENSG00000181690	-0.3956924548839141	[354]	[735]	-3	hSpCas9	negative selection	2351654
56167366	56167389	8	-	24336569	KBM7	viability	ACGTTTAAGTGCGAAGAATGTGG	PLAG1	ENSG00000181690	-0.24836479009491164	[492]	[1131]	-2	hSpCas9	negative selection	2351655
56167378	56167401	8	+	24336569	KBM7	viability	CACTTAAACGTCTCTTTGTTAGG	PLAG1	ENSG00000181690	0.738885481043361	[211]	[964]	6	hSpCas9	negative selection	2351656
56167391	56167414	8	+	24336569	KBM7	viability	CTTTGTTAGGGTCGTGTGTATGG	PLAG1	ENSG00000181690	0.17418874517082122	[515]	[1587]	1	hSpCas9	negative selection	2351657
56167418	56167441	8	+	24336569	KBM7	viability	GATTCTTCAGATGATCTTTCCGG	PLAG1	ENSG00000181690	0.1562316188056394	[582]	[1771]	1	hSpCas9	negative selection	2351658
56167451	56167474	8	+	24336569	KBM7	viability	TCTCACAATAATTACACTTGTGG	PLAG1	ENSG00000181690	0.25912857652464294	[741]	[2421]	2	hSpCas9	negative selection	2351659
56169751	56169774	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGGCTGGTCTTGAACTCCAGG	PLAG1	ENSG00000181690	1.1112377139242877	[89,193]	[7,132]	4	dCas9-VP64	positive selection	2451719
56169751	56169774	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGGCTGGTCTTGAACTCCAGG	PLAG1	ENSG00000181690	-0.05379639634842043	[67,143]	[20,43]	0	dCas9-VP64	positive selection	2546974
56167130	56167153	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.07462246316671889	[2,2]	[2,2]	1	hSpCas9	positive selection	3011740
56167294	56167317	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-0.10051850218782968	[4,4]	[5,2]	-1	hSpCas9	positive selection	3011741
56167086	56167109	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	-0.30059339605394464	[3,3]	[1,2]	-4	hSpCas9	positive selection	3011742
56167137	56167160	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTGTCTCCGGACATCCTTTCGG	PLAG1	ENSG00000181690	0.3366741820699233	[4,4]	[3,5]	7	hSpCas9	positive selection	3011743
56167130	56167153	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.22565716826895688	[2,2]	[2,1]	4	hSpCas9	positive selection	3079598
56167294	56167317	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-0.11655619097282569	[4,4]	[3,2]	-2	hSpCas9	positive selection	3079599
56167086	56167109	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	0.6111348951910403	[3,3]	[2,4]	8	hSpCas9	positive selection	3079600
56167137	56167160	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTGTCTCCGGACATCCTTTCGG	PLAG1	ENSG00000181690	0.12061444378222794	[4,4]	[4,2]	2	hSpCas9	positive selection	3079601
56167302	56167325		+	24336571	A375	resistance to PLX after 7 days	ACCACTTGTTGCGGCATGCAAGG	PLAG1	ENSG00000181690	-0.04256284249407205	[46,45]	[47,41]	-1	hSpCas9	positive selection	3136012
56167167	56167190		-	24336571	A375	resistance to PLX after 7 days	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	0.07480223478281012	[56,50]	[56,55]	2	hSpCas9	positive selection	3136013
56168193	56168216		+	24336571	A375	resistance to PLX after 7 days	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	-0.05592446165094955	[22,22]	[21,20]	-2	hSpCas9	positive selection	3136015
56168250	56168273		-	24336571	A375	resistance to PLX after 7 days	GCGATGGCCACTGTCATTCCTGG	PLAG1	ENSG00000181690	-0.23507754408975096	[14,13]	[10,12]	-7	hSpCas9	positive selection	3136016
56167302	56167325		+	24336571	A375	resistance to PLX after 14 days	ACCACTTGTTGCGGCATGCAAGG	PLAG1	ENSG00000181690	-0.2780971095528648	[41,40]	[16,13]	-3	hSpCas9	positive selection	3193805
56167167	56167190		-	24336571	A375	resistance to PLX after 14 days	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	0.14994337792413814	[54,44]	[22,27]	1	hSpCas9	positive selection	3193806
56168193	56168216		+	24336571	A375	resistance to PLX after 14 days	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	-0.781160278783769	[26,21]	[4,6]	-8	hSpCas9	positive selection	3193808
56168250	56168273		-	24336571	A375	resistance to PLX after 14 days	GCGATGGCCACTGTCATTCCTGG	PLAG1	ENSG00000181690	-1.043148582395597	[16,14]	[2,2]	-9	hSpCas9	positive selection	3193809
56167302	56167325		+	24336571	A375	viability after 7 days	ACCACTTGTTGCGGCATGCAAGG	PLAG1	ENSG00000181690	0.8858582323691986	[25]	[46,45]	9	hSpCas9	negative selection	3251598
56167167	56167190		-	24336571	A375	viability after 7 days	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	0.06748884920196319	[53]	[56,50]	1	hSpCas9	negative selection	3251599
56168193	56168216		+	24336571	A375	viability after 7 days	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.3558713697253482	[18]	[22,22]	5	hSpCas9	negative selection	3251601
56168250	56168273		-	24336571	A375	viability after 7 days	GCGATGGCCACTGTCATTCCTGG	PLAG1	ENSG00000181690	0.8400334676084262	[7]	[14,13]	9	hSpCas9	negative selection	3251602
56167302	56167325		+	24336571	A375	viability after 14 days	ACCACTTGTTGCGGCATGCAAGG	PLAG1	ENSG00000181690	0.7383506890976188	[25]	[41,40]	8	hSpCas9	negative selection	3309391
56167167	56167190		-	24336571	A375	viability after 14 days	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.023835801408182755	[53]	[54,44]	0	hSpCas9	negative selection	3309392
56168193	56168216		+	24336571	A375	viability after 14 days	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.45803532137265174	[18]	[26,21]	6	hSpCas9	negative selection	3309394
56168250	56168273		-	24336571	A375	viability after 14 days	GCGATGGCCACTGTCATTCCTGG	PLAG1	ENSG00000181690	1.0135873393864279	[7]	[16,14]	9	hSpCas9	negative selection	3309395
56168208	56168231	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	1.3031299010589596	[61,61]	[0,0]	5	hSpCas9	positive selection	3386165
56167148	56167171	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	-0.40088527130595975	[201,201]	[0,0]	-3	hSpCas9	positive selection	3386166
56167303	56167326	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.5568864933047428	[103,103]	[0,0]	3	hSpCas9	positive selection	3386167
56167130	56167153	8	-	26780180	HT29	viability (Avana library 4 designs)	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	2.77893830332333	[]	[]	8	hSpCas9	negative selection	3449831
56167293	56167316	8	+	26780180	HT29	viability (Avana library 4 designs)	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	0.605257890174298	[]	[]	2	hSpCas9	negative selection	3449832
56167085	56167108	8	+	26780180	HT29	viability (Avana library 4 designs)	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	1.0961561043616	[]	[]	4	hSpCas9	negative selection	3449833
56167136	56167159	8	+	26780180	HT29	viability (Avana library 4 designs)	TGTGTCTCCGGACATCCTTTCGG	PLAG1	ENSG00000181690	-0.376955180351119	[]	[]	-6	hSpCas9	negative selection	3449834
56167136	56167159	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGTCTCCGGACATCCTTTCGG	PLAG1	ENSG00000181690	5.14924124410989	[]	[]	8	hSpCas9	negative selection	3544782
56167293	56167316	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	3.81433810685461	[]	[]	6	hSpCas9	negative selection	3544783
56167130	56167153	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	3.94931265171203	[]	[]	6	hSpCas9	negative selection	3544784
56167085	56167108	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	0.141898999502313	[]	[]	0	hSpCas9	negative selection	3544785
56167394	56167417	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTTAGGGTCGTGTGTATGGAGG	PLAG1	ENSG00000181690	-0.428564067865535	[]	[]	0	hSpCas9	negative selection	3544786
56167277	56167300	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAACATACCTTACAGGTGAGG	PLAG1	ENSG00000181690	5.30614363310891	[]	[]	8	hSpCas9	negative selection	3544787
56167136	56167159	8	+	26780180	A375	viability (Avana lentiGuide)	TGTGTCTCCGGACATCCTTTCGG	PLAG1	ENSG00000181690	-4.87331926334474	[]	[]	-8	hSpCas9	negative selection	3653441
56167293	56167316	8	+	26780180	A375	viability (Avana lentiGuide)	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	0.827695874493246	[]	[]	1	hSpCas9	negative selection	3653442
56167130	56167153	8	-	26780180	A375	viability (Avana lentiGuide)	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	1.0086991026894	[]	[]	1	hSpCas9	negative selection	3653443
56167085	56167108	8	+	26780180	A375	viability (Avana lentiGuide)	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	4.60874765121028	[]	[]	4	hSpCas9	negative selection	3653444
56167394	56167417	8	+	26780180	A375	viability (Avana lentiGuide)	TGTTAGGGTCGTGTGTATGGAGG	PLAG1	ENSG00000181690	0.224483007775285	[]	[]	0	hSpCas9	negative selection	3653445
56167277	56167300	8	+	26780180	A375	viability (Avana lentiGuide)	GCAAACATACCTTACAGGTGAGG	PLAG1	ENSG00000181690	-0.526942921212807	[]	[]	-1	hSpCas9	negative selection	3653446
56167136	56167159	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGTCTCCGGACATCCTTTCGG	PLAG1	ENSG00000181690	0.15487452962214146	[5]	[6,6]	4	hSpCas9	positive selection	3762100
56167293	56167316	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	0.13086526258888145	[5]	[7,5]	3	hSpCas9	positive selection	3762101
56167130	56167153	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.054053032527294764	[3]	[4,3]	1	hSpCas9	positive selection	3762102
56167085	56167108	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	0.11016431288350542	[5]	[6,5]	3	hSpCas9	positive selection	3762103
56167394	56167417	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTTAGGGTCGTGTGTATGGAGG	PLAG1	ENSG00000181690	0.08149185002121873	[5]	[5,5]	2	hSpCas9	positive selection	3762104
56167277	56167300	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAACATACCTTACAGGTGAGG	PLAG1	ENSG00000181690	0.24429638364015263	[4]	[5,4]	7	hSpCas9	positive selection	3762105
56167136	56167159	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGTCTCCGGACATCCTTTCGG	PLAG1	ENSG00000181690	0.27537619816219416	[6]	[6,6]	7	hSpCas9	positive selection	3870707
56167293	56167316	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	0.16089445564666793	[6]	[7,5]	4	hSpCas9	positive selection	3870708
56167130	56167153	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.17143060897232187	[4]	[5,3]	4	hSpCas9	positive selection	3870709
56167085	56167108	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	0.3292825475518646	[5]	[6,5]	8	hSpCas9	positive selection	3870710
56167394	56167417	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTTAGGGTCGTGTGTATGGAGG	PLAG1	ENSG00000181690	-0.01570458488836543	[6]	[5,4]	0	hSpCas9	positive selection	3870711
56167277	56167300	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAACATACCTTACAGGTGAGG	PLAG1	ENSG00000181690	-0.23152080361365565	[4]	[2,3]	-3	hSpCas9	positive selection	3870712
56167167	56167190	8	-	26780180	A375	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	2.16471974036632	[]	[]	9	hSpCas9	negative selection	3981526
56167148	56167171	8	+	26780180	A375	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.192073237531513	[]	[]	0	hSpCas9	negative selection	3981527
56168193	56168216	8	+	26780180	A375	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.755701199168061	[]	[]	3	hSpCas9	negative selection	3981528
56168208	56168231	8	-	26780180	A375	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.834557652846224	[]	[]	3	hSpCas9	negative selection	3981529
56167303	56167326	8	-	26780180	A375	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.924683968063944	[]	[]	4	hSpCas9	negative selection	3981530
56167043	56167066	8	+	26780180	A375	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	1.13335843559214	[]	[]	6	hSpCas9	negative selection	3981531
56167167	56167190	8	-	26780180	HT29	viability (GeCKOv2 library)	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	2.47801152621267	[]	[]	9	hSpCas9	negative selection	4089492
56167148	56167171	8	+	26780180	HT29	viability (GeCKOv2 library)	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.766629184713574	[]	[]	3	hSpCas9	negative selection	4089493
56168193	56168216	8	+	26780180	HT29	viability (GeCKOv2 library)	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.851283084378018	[]	[]	3	hSpCas9	negative selection	4089494
56168208	56168231	8	-	26780180	HT29	viability (GeCKOv2 library)	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	1.04359019486049	[]	[]	5	hSpCas9	negative selection	4089495
56167303	56167326	8	-	26780180	HT29	viability (GeCKOv2 library)	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	1.33820185331909	[]	[]	6	hSpCas9	negative selection	4089496
56167043	56167066	8	+	26780180	HT29	viability (GeCKOv2 library)	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.995078004079362	[]	[]	4	hSpCas9	negative selection	4089497
56167302	56167325	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCACTTGTTGCGGCATGCAAGG	PLAG1	ENSG00000181690	0.1379678600424687	[5]	[3,3]	3	hSpCas9	positive selection	4161004
56167167	56167190	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	0.19658099762124448	[5]	[4,4]	5	hSpCas9	positive selection	4161005
56168193	56168216	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	-0.05035695405375751	[4]	[2,2]	-1	hSpCas9	positive selection	4161007
56168250	56168273	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGATGGCCACTGTCATTCCTGG	PLAG1	ENSG00000181690	-0.08127370239229777	[3]	[2,1]	-2	hSpCas9	positive selection	4161008
56167302	56167325	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCACTTGTTGCGGCATGCAAGG	PLAG1	ENSG00000181690	1.0240953478463632	[4]	[5,4,3,3]	7	hSpCas9	positive selection	4225026
56167167	56167190	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	0.8530384032714866	[5]	[3,4,3,3]	5	hSpCas9	positive selection	4225027
56168193	56168216	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	1.1486905570771828	[3]	[3,1,2,4]	8	hSpCas9	positive selection	4225029
56168250	56168273	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGATGGCCACTGTCATTCCTGG	PLAG1	ENSG00000181690	0.4149257527838478	[3]	[4,2,1,0]	3	hSpCas9	positive selection	4225030
56167167	56167190	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.37689275693266466	[3]	[2,1]	-7	hSpCas9	positive selection	4290600
56167043	56167066	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.05172315992398524	[3]	[2,2]	1	hSpCas9	positive selection	4290601
56168193	56168216	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	-0.22032301741732285	[1]	[1,0]	-4	hSpCas9	positive selection	4290602
56168208	56168231	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.09380706364437263	[2]	[3,0]	2	hSpCas9	positive selection	4354852
56167148	56167171	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	-0.23557637196055997	[2]	[2,0]	-5	hSpCas9	positive selection	4354853
56167303	56167326	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.3901700256638169	[2]	[1,0]	-7	hSpCas9	positive selection	4354854
56167044	56167066	8	+	27760321	OCIAML3	viability	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.008956699425095124	[409,399]	[295,349]	0	hSpCas9	negative selection	4428318
56167130	56167152	8	-	27760321	OCIAML3	viability	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.24750981124386462	[518,439]	[302,626]	3	hSpCas9	negative selection	4428319
56167151	56167173	8	-	27760321	OCIAML3	viability	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.43798156924824594	[573,482]	[329,269]	-4	hSpCas9	negative selection	4428320
56167170	56167192	8	+	27760321	OCIAML3	viability	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.647725635886579	[499,444]	[149,346]	-6	hSpCas9	negative selection	4428321
56167303	56167325	8	-	27760321	OCIAML3	viability	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.26947201245911195	[442,402]	[289,539]	3	hSpCas9	negative selection	4428322
56167044	56167066	8	+	27760321	OCIAML2	viability	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.26997308637197037	[409,399]	[223,335]	-3	hSpCas9	negative selection	4511781
56167130	56167152	8	-	27760321	OCIAML2	viability	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.6012824595332867	[518,439]	[462,748]	7	hSpCas9	negative selection	4511782
56167151	56167173	8	-	27760321	OCIAML2	viability	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.21295859786464033	[573,482]	[319,429]	-3	hSpCas9	negative selection	4511783
56167170	56167192	8	+	27760321	OCIAML2	viability	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.16513213354204026	[499,444]	[304,386]	-2	hSpCas9	negative selection	4511784
56167303	56167325	8	-	27760321	OCIAML2	viability	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.4631324152284376	[442,402]	[448,500]	6	hSpCas9	negative selection	4511785
56167044	56167066	8	+	27760321	MV411	viability	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.727176632703057	[409,399]	[178,135]	-5	hSpCas9	negative selection	4595244
56167130	56167152	8	-	27760321	MV411	viability	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.45738663519064765	[518,439]	[376,516]	3	hSpCas9	negative selection	4595245
56167151	56167173	8	-	27760321	MV411	viability	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	-0.14838669537261806	[573,482]	[167,531]	-1	hSpCas9	negative selection	4595246
56167170	56167192	8	+	27760321	MV411	viability	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	0.23480815224655815	[499,444]	[84,788]	1	hSpCas9	negative selection	4595247
56167303	56167325	8	-	27760321	MV411	viability	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.5885164248414357	[442,402]	[526,257]	4	hSpCas9	negative selection	4595248
56167044	56167066	8	+	27760321	HL60	viability	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.13761802786777103	[409,399]	[364,233]	-1	hSpCas9	negative selection	4678707
56167130	56167152	8	-	27760321	HL60	viability	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.4743835040403574	[518,439]	[212,352]	-5	hSpCas9	negative selection	4678708
56167151	56167173	8	-	27760321	HL60	viability	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.8968361791032515	[573,482]	[777,824]	8	hSpCas9	negative selection	4678709
56167170	56167192	8	+	27760321	HL60	viability	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.37497236001021356	[499,444]	[203,395]	-4	hSpCas9	negative selection	4678710
56167303	56167325	8	-	27760321	HL60	viability	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.44060905880120116	[442,402]	[457,479]	5	hSpCas9	negative selection	4678711
56167044	56167066	8	+	27760321	HT1080	viability	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.8990762199625644	[399,311]	[76,74]	-4	hSpCas9	negative selection	4762170
56167130	56167152	8	-	27760321	HT1080	viability	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.26823622771066014	[439,343]	[189,185]	1	hSpCas9	negative selection	4762171
56167151	56167173	8	-	27760321	HT1080	viability	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	1.2232456164699126	[482,376]	[366,435]	6	hSpCas9	negative selection	4762172
56167170	56167192	8	+	27760321	HT1080	viability	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.5772916027989851	[444,346]	[120,88]	-3	hSpCas9	negative selection	4762173
56167303	56167325	8	-	27760321	HT1080	viability	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.5403270802554134	[402,314]	[52,147]	-2	hSpCas9	negative selection	4762174
56167044	56167066	8	+	27760321	HT29	viability after 7 days	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.701469305688772	[399,311]	[167,384,274]	-7	hSpCas9	negative selection	4845633
56167130	56167152	8	-	27760321	HT29	viability after 7 days	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.17054068443418088	[439,343]	[443,406,489]	-3	hSpCas9	negative selection	4845634
56167151	56167173	8	-	27760321	HT29	viability after 7 days	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.09859480154329825	[482,376]	[752,643,406]	1	hSpCas9	negative selection	4845635
56167170	56167192	8	+	27760321	HT29	viability after 7 days	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	0.03361762785782785	[444,346]	[609,530,436]	0	hSpCas9	negative selection	4845636
56167303	56167325	8	-	27760321	HT29	viability after 7 days	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.025954459953253586	[402,314]	[496,504,412]	0	hSpCas9	negative selection	4845637
56167044	56167066	8	+	27760321	HT29	viability after 25 days	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.44645659891368505	[399,311]	[409,206,267]	-4	hSpCas9	negative selection	4929096
56167130	56167152	8	-	27760321	HT29	viability after 25 days	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.2702713422953417	[439,343]	[148,356,650]	-3	hSpCas9	negative selection	4929097
56167151	56167173	8	-	27760321	HT29	viability after 25 days	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.332794207004206	[482,376]	[609,802,422]	3	hSpCas9	negative selection	4929098
56167170	56167192	8	+	27760321	HT29	viability after 25 days	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.4657191466661369	[444,346]	[241,279,481]	-4	hSpCas9	negative selection	4929099
56167303	56167325	8	-	27760321	HT29	viability after 25 days	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.41125126348630336	[402,314]	[418,731,486]	4	hSpCas9	negative selection	4929100
56167044	56167066	8	+	27760321	HT29	viability after 22 days	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.16657805452765606	[399,311]	[668,364,344]	1	hSpCas9	negative selection	5012559
56167130	56167152	8	-	27760321	HT29	viability after 22 days	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.7351929437172774	[439,343]	[149,302,367]	-6	hSpCas9	negative selection	5012560
56167151	56167173	8	-	27760321	HT29	viability after 22 days	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.4121539605915768	[482,376]	[763,623,592]	4	hSpCas9	negative selection	5012561
56167170	56167192	8	+	27760321	HT29	viability after 22 days	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.41135245400865283	[444,346]	[248,355,430]	-4	hSpCas9	negative selection	5012562
56167303	56167325	8	-	27760321	HT29	viability after 22 days	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.13734646344198012	[402,314]	[458,397,512]	1	hSpCas9	negative selection	5012563
56167044	56167066	8	+	27760321	HT29	viability after 19 days	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.23202271483824322	[399,311]	[463,294,294]	-2	hSpCas9	negative selection	5096022
56167130	56167152	8	-	27760321	HT29	viability after 19 days	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.09869291735298273	[439,343]	[219,486,523]	-1	hSpCas9	negative selection	5096023
56167151	56167173	8	-	27760321	HT29	viability after 19 days	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.47473282294281133	[482,376]	[650,1076,331]	5	hSpCas9	negative selection	5096024
56167170	56167192	8	+	27760321	HT29	viability after 19 days	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	0.13379749251720421	[444,346]	[204,710,541]	1	hSpCas9	negative selection	5096025
56167303	56167325	8	-	27760321	HT29	viability after 19 days	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.632382270346662	[402,314]	[358,1070,456]	6	hSpCas9	negative selection	5096026
56167044	56167066	8	+	27760321	HT29	viability after 16 days	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.14339603742423812	[399,311]	[409,260,417]	-1	hSpCas9	negative selection	5179485
56167130	56167152	8	-	27760321	HT29	viability after 16 days	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.08904410946114699	[439,343]	[297,420,506]	-1	hSpCas9	negative selection	5179486
56167151	56167173	8	-	27760321	HT29	viability after 16 days	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.12603911233388904	[482,376]	[793,461,345]	1	hSpCas9	negative selection	5179487
56167170	56167192	8	+	27760321	HT29	viability after 16 days	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.162451627512878	[444,346]	[283,391,500]	-2	hSpCas9	negative selection	5179488
56167303	56167325	8	-	27760321	HT29	viability after 16 days	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.2507686113066222	[402,314]	[378,531,511]	2	hSpCas9	negative selection	5179489
56167044	56167066	8	+	27760321	HT29	viability after 13 days	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.5956485605812339	[399,311]	[230,299,287]	-6	hSpCas9	negative selection	5262948
56167130	56167152	8	-	27760321	HT29	viability after 13 days	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.33615025191276	[439,343]	[175,336,555]	-4	hSpCas9	negative selection	5262949
56167151	56167173	8	-	27760321	HT29	viability after 13 days	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.6055644835617777	[482,376]	[814,824,643]	7	hSpCas9	negative selection	5262950
56167170	56167192	8	+	27760321	HT29	viability after 13 days	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.6078047690751376	[444,346]	[241,319,339]	-6	hSpCas9	negative selection	5262951
56167303	56167325	8	-	27760321	HT29	viability after 13 days	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.104737969755544	[402,314]	[493,410,438]	1	hSpCas9	negative selection	5262952
56167044	56167066	8	+	27760321	HT29	viability after 10 days	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.7044935684790594	[399,311]	[239,202,370]	-7	hSpCas9	negative selection	5346411
56167130	56167152	8	-	27760321	HT29	viability after 10 days	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.39811497542054963	[439,343]	[274,388,448]	-5	hSpCas9	negative selection	5346412
56167151	56167173	8	-	27760321	HT29	viability after 10 days	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.11700185157409254	[482,376]	[717,428,594]	1	hSpCas9	negative selection	5346413
56167170	56167192	8	+	27760321	HT29	viability after 10 days	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.4876487750001708	[444,346]	[496,212,343]	-6	hSpCas9	negative selection	5346414
56167303	56167325	8	-	27760321	HT29	viability after 10 days	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.12608029502943996	[402,314]	[395,599,474]	1	hSpCas9	negative selection	5346415
56167044	56167066	8	+	27760321	MOLM13	viability	CTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.5949282492395037	[409,399]	[521,195]	4	hSpCas9	negative selection	5429874
56167130	56167152	8	-	27760321	MOLM13	viability	GATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-1.0547552515566336	[518,439]	[78,172]	-6	hSpCas9	negative selection	5429875
56167151	56167173	8	-	27760321	MOLM13	viability	CGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.05937051959024131	[573,482]	[214,389]	0	hSpCas9	negative selection	5429876
56167170	56167192	8	+	27760321	MOLM13	viability	GCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-2.6290711709220456	[499,444]	[82,8]	-8	hSpCas9	negative selection	5429877
56167303	56167325	8	-	27760321	MOLM13	viability	CCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.29820396565449986	[442,402]	[302,284]	2	hSpCas9	negative selection	5429878
56210842	56210865	8	-	27661255	K562	viability	GACCCGAAGGTGAGGTCGGTGGG	PLAG1	ENSG00000181690	0.29218471925811995	[1191,1483]	[1430,1194]	8	dCas9-KRAB	negative selection	5502325
56211063	56211086	8	-	27661255	K562	viability	GTTTAGCGGGAGAAATATCAGGG	PLAG1	ENSG00000181690	0.07457596669900468	[1684,1925]	[1709,1348]	2	dCas9-KRAB	negative selection	5502326
56211258	56211281	8	-	27661255	K562	viability	GGGCAGCGCATACACTACAATGG	PLAG1	ENSG00000181690	-0.01698235529044656	[1032,942]	[885,691]	0	dCas9-KRAB	negative selection	5502327
56211287	56211310	8	-	27661255	K562	viability	GGCGGCGGCAGCTGCAAGTTGGG	PLAG1	ENSG00000181690	0.14631858542562848	[536,442]	[465,407]	5	dCas9-KRAB	negative selection	5502328
56167167	56167190	8	-	27260156	BXPC3	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.2892943009577067	[568]	[456,441,459,604]	-6	hSpCas9	negative selection	5563060
56167043	56167066	8	+	27260156	BXPC3	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.028950138684165433	[560]	[478,506,713,617]	0	hSpCas9	negative selection	5563061
56168193	56168216	8	+	27260156	BXPC3	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.6418567763350944	[152]	[289,158,221,336]	9	hSpCas9	negative selection	5563062
56168208	56168231	8	-	27260156	BXPC3	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.1816004237705634	[208]	[265,205,216,307]	4	hSpCas9	negative selection	5627312
56167148	56167171	8	+	27260156	BXPC3	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.20345430924860408	[358]	[441,309,558,421]	4	hSpCas9	negative selection	5627313
56167303	56167326	8	-	27260156	BXPC3	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.017960416529369416	[338]	[335,406,301,349]	0	hSpCas9	negative selection	5627314
56167167	56167190	8	-	27260156	A673	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.4110176262559072	[568]	[596,471,559,430]	-7	hSpCas9	negative selection	5684311
56167043	56167066	8	+	27260156	A673	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.28987776236612556	[560]	[598,514,564,528]	-6	hSpCas9	negative selection	5684312
56168193	56168216	8	+	27260156	A673	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.18787866884799764	[152]	[206,230,173,224]	4	hSpCas9	negative selection	5684313
56168208	56168231	8	-	27260156	A673	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.18297160516861077	[208]	[252,321,265,293]	4	hSpCas9	negative selection	5748563
56167148	56167171	8	+	27260156	A673	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.2919097784837644	[358]	[596,490,503,526]	6	hSpCas9	negative selection	5748564
56167303	56167326	8	-	27260156	A673	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.10411101720748517	[338]	[401,289,468,355]	-3	hSpCas9	negative selection	5748565
56167167	56167190	8	-	27260156	A375	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.2512595015548328	[568]	[495,672,724,374]	-4	hSpCas9	negative selection	5805562
56167043	56167066	8	+	27260156	A375	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.19417163820907385	[560]	[591,659,933,790]	3	hSpCas9	negative selection	5805563
56168193	56168216	8	+	27260156	A375	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.4784178014786713	[152]	[228,302,227,242]	7	hSpCas9	negative selection	5805564
56168208	56168231	8	-	27260156	A375	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.42561894581104043	[208]	[277,333,391,308]	6	hSpCas9	negative selection	5869814
56167148	56167171	8	+	27260156	A375	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.3766637397563747	[358]	[490,795,571,371]	5	hSpCas9	negative selection	5869815
56167303	56167326	8	-	27260156	A375	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.21663518300617435	[338]	[509,361,320,190]	-3	hSpCas9	negative selection	5869816
56167167	56167190	8	-	27260156	COLO741	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.2968933063287706	[568]	[712,533,540]	-6	hSpCas9	negative selection	5926813
56167043	56167066	8	+	27260156	COLO741	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.1525981728448509	[560]	[1055,947,433]	3	hSpCas9	negative selection	5926814
56168193	56168216	8	+	27260156	COLO741	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.14152232617666627	[152]	[153,280,206]	3	hSpCas9	negative selection	5926815
56168208	56168231	8	-	27260156	COLO741	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.1927373703980927	[208]	[421,397,118]	4	hSpCas9	negative selection	5991065
56167148	56167171	8	+	27260156	COLO741	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.12043461762567886	[358]	[551,431,513]	2	hSpCas9	negative selection	5991066
56167303	56167326	8	-	27260156	COLO741	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.044356352787950803	[338]	[462,369,428]	-1	hSpCas9	negative selection	5991067
56167167	56167190	8	-	27260156	CAL120	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.43484797219397664	[568]	[597,552,432]	-6	hSpCas9	negative selection	6048064
56167043	56167066	8	+	27260156	CAL120	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.12408257024961133	[560]	[1047,443,831]	1	hSpCas9	negative selection	6048065
56168193	56168216	8	+	27260156	CAL120	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.30571012681848386	[152]	[341,203,176]	4	hSpCas9	negative selection	6048066
56168208	56168231	8	-	27260156	CAL120	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.27532868762423224	[208]	[345,295,306]	4	hSpCas9	negative selection	6112316
56167148	56167171	8	+	27260156	CAL120	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.2384399037555173	[358]	[446,493,625]	3	hSpCas9	negative selection	6112317
56167303	56167326	8	-	27260156	CAL120	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.31129824315606897	[338]	[325,724,489]	5	hSpCas9	negative selection	6112318
56167167	56167190	8	-	27260156	CADOES1	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.6049126091236655	[568]	[310,328,476,271]	-8	hSpCas9	negative selection	6169315
56167043	56167066	8	+	27260156	CADOES1	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.05646670120183839	[560]	[432,337,675,561]	-1	hSpCas9	negative selection	6169316
56168193	56168216	8	+	27260156	CADOES1	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.429953865367265	[152]	[168,228,226,139]	7	hSpCas9	negative selection	6169317
56168208	56168231	8	-	27260156	CADOES1	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	-0.1361620282268865	[208]	[154,155,206,189]	-2	hSpCas9	negative selection	6233567
56167148	56167171	8	+	27260156	CADOES1	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.15045564379520301	[358]	[260,444,349,428]	2	hSpCas9	negative selection	6233568
56167303	56167326	8	-	27260156	CADOES1	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.7649183389043259	[338]	[214,122,191,212]	-8	hSpCas9	negative selection	6233569
56167167	56167190	8	-	27260156	EWS502	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.31907257620102386	[568]	[654,447,303,502]	-5	hSpCas9	negative selection	6290566
56167043	56167066	8	+	27260156	EWS502	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.03140965411631247	[560]	[753,604,467,577]	0	hSpCas9	negative selection	6290567
56168193	56168216	8	+	27260156	EWS502	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.1486537740042213	[152]	[189,201,194,124]	2	hSpCas9	negative selection	6290568
56168208	56168231	8	-	27260156	EWS502	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.4963305239815664	[208]	[243,313,259,446]	8	hSpCas9	negative selection	6354818
56167148	56167171	8	+	27260156	EWS502	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.21063057000663812	[358]	[270,426,631,452]	3	hSpCas9	negative selection	6354819
56167303	56167326	8	-	27260156	EWS502	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.025878984410728167	[338]	[221,378,548,270]	0	hSpCas9	negative selection	6354820
56167167	56167190	8	-	27260156	EW8	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.10949679074917673	[568]	[631,369,271,482]	-2	hSpCas9	negative selection	6411817
56167043	56167066	8	+	27260156	EW8	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.15947319454853975	[560]	[668,575,467,341]	3	hSpCas9	negative selection	6411818
56168193	56168216	8	+	27260156	EW8	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.6029887328886188	[152]	[205,276,160,115]	9	hSpCas9	negative selection	6411819
56168208	56168231	8	-	27260156	EW8	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.5189619626422155	[208]	[323,319,127,226]	8	hSpCas9	negative selection	6476069
56167148	56167171	8	+	27260156	EW8	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.32465204941460785	[358]	[228,494,274,457]	6	hSpCas9	negative selection	6476070
56167303	56167326	8	-	27260156	EW8	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.13008156504485296	[338]	[233,388,281,292]	2	hSpCas9	negative selection	6476071
56167167	56167190	8	-	27260156	CORL105	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.1513204986124796	[568]	[564,516,737,600]	-3	hSpCas9	negative selection	6533068
56167043	56167066	8	+	27260156	CORL105	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.21561665302767777	[560]	[570,435,575,682]	-4	hSpCas9	negative selection	6533069
56168193	56168216	8	+	27260156	CORL105	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.46507119386436613	[152]	[225,236,301,231]	8	hSpCas9	negative selection	6533070
56168208	56168231	8	-	27260156	CORL105	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.3285392525297903	[208]	[222,285,369,356]	6	hSpCas9	negative selection	6597320
56167148	56167171	8	+	27260156	CORL105	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.3153666315949998	[358]	[556,406,686,469]	6	hSpCas9	negative selection	6597321
56167303	56167326	8	-	27260156	CORL105	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.43452777728603065	[338]	[317,247,248,353]	-7	hSpCas9	negative selection	6597322
56167167	56167190	8	-	27260156	HS294T	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.2546850968976816	[568]	[154,153,211,226]	-4	hSpCas9	negative selection	6654319
56167043	56167066	8	+	27260156	HS294T	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.23251306080856005	[560]	[204,158,156,221]	-3	hSpCas9	negative selection	6654320
56168193	56168216	8	+	27260156	HS294T	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.7290379468185724	[152]	[57,178,72,79]	8	hSpCas9	negative selection	6654321
56168208	56168231	8	-	27260156	HS294T	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.6462738126561325	[208]	[70,96,121,240]	8	hSpCas9	negative selection	6718571
56167148	56167171	8	+	27260156	HS294T	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.38020033037741613	[358]	[160,151,145,282]	5	hSpCas9	negative selection	6718572
56167303	56167326	8	-	27260156	HS294T	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.37460055847188334	[338]	[99,119,84,97]	-5	hSpCas9	negative selection	6718573
56167167	56167190	8	-	27260156	HCC44	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.5689867633465933	[568]	[302,471,624,349]	-7	hSpCas9	negative selection	6775570
56167043	56167066	8	+	27260156	HCC44	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.09120146617913669	[560]	[468,488,832,629]	-1	hSpCas9	negative selection	6775571
56168193	56168216	8	+	27260156	HCC44	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.8884219539720942	[152]	[408,114,474,342]	9	hSpCas9	negative selection	6775572
56168208	56168231	8	-	27260156	HCC44	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.6687259454052972	[208]	[407,306,454,356]	9	hSpCas9	negative selection	6839822
56167148	56167171	8	+	27260156	HCC44	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.3797085467289776	[358]	[521,567,598,428]	6	hSpCas9	negative selection	6839823
56167303	56167326	8	-	27260156	HCC44	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.29478970019883033	[338]	[437,154,314,371]	-5	hSpCas9	negative selection	6839824
56167167	56167190	8	-	27260156	G402	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.2723210771574622	[568]	[696,428,787,400]	-3	hSpCas9	negative selection	6896821
56167043	56167066	8	+	27260156	G402	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.28242035216881345	[560]	[1048,775,846,689]	3	hSpCas9	negative selection	6896822
56168193	56168216	8	+	27260156	G402	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.7937041661849028	[152]	[425,328,221,330]	8	hSpCas9	negative selection	6896823
56168208	56168231	8	-	27260156	G402	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.29956345042853516	[208]	[345,138,327,429]	4	hSpCas9	negative selection	6961073
56167148	56167171	8	+	27260156	G402	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.5900960013811621	[358]	[870,469,618,692]	7	hSpCas9	negative selection	6961074
56167303	56167326	8	-	27260156	G402	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.2300162119640419	[338]	[849,681,285,198]	3	hSpCas9	negative selection	6961075
56167167	56167190	8	-	27260156	L33	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.24707367699073682	[568]	[546,218,312,337]	-5	hSpCas9	negative selection	7018072
56167043	56167066	8	+	27260156	L33	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.4212133427870409	[560]	[383,151,261,503]	-7	hSpCas9	negative selection	7018073
56168193	56168216	8	+	27260156	L33	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	-0.029957475707737435	[152]	[113,70,127,109]	0	hSpCas9	negative selection	7018074
56168208	56168231	8	-	27260156	L33	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	-0.013477010758778274	[208]	[189,48,154,271]	0	hSpCas9	negative selection	7082324
56167148	56167171	8	+	27260156	L33	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.18547754685045725	[358]	[426,227,194,338]	4	hSpCas9	negative selection	7082325
56167303	56167326	8	-	27260156	L33	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.540447305707505	[338]	[232,115,165,152]	-8	hSpCas9	negative selection	7082326
56167167	56167190	8	-	27260156	K562	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.30586450510489305	[568]	[419,523,284,409]	-4	hSpCas9	negative selection	7139323
56167043	56167066	8	+	27260156	K562	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.3040497887370177	[560]	[708,544,694,521]	4	hSpCas9	negative selection	7139324
56168193	56168216	8	+	27260156	K562	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.8296158444728898	[152]	[361,132,303,176]	9	hSpCas9	negative selection	7139325
56168208	56168231	8	-	27260156	K562	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.35924149650365045	[208]	[255,154,168,353]	4	hSpCas9	negative selection	7203575
56167148	56167171	8	+	27260156	K562	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.15816109777038367	[358]	[326,373,436,288]	2	hSpCas9	negative selection	7203576
56167303	56167326	8	-	27260156	K562	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.8165027340342397	[338]	[122,284,146,133]	-7	hSpCas9	negative selection	7203577
56167167	56167190	8	-	27260156	HT29	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.6171401299828123	[568]	[400,617,358,434]	-8	hSpCas9	negative selection	7260574
56167043	56167066	8	+	27260156	HT29	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.13366038474419395	[560]	[758,581,471,669]	-3	hSpCas9	negative selection	7260575
56168193	56168216	8	+	27260156	HT29	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.4362937763094856	[152]	[281,255,257,215]	8	hSpCas9	negative selection	7260576
56168208	56168231	8	-	27260156	HT29	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.2717048348133885	[208]	[333,347,328,228]	5	hSpCas9	negative selection	7324826
56167148	56167171	8	+	27260156	HT29	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.2105741447240834	[358]	[533,560,357,562]	4	hSpCas9	negative selection	7324827
56167303	56167326	8	-	27260156	HT29	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.5705443918613369	[338]	[392,201,225,287]	-7	hSpCas9	negative selection	7324828
56167167	56167190	8	-	27260156	MHHES1	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.261855481934055	[568]	[671,472,408,571]	-5	hSpCas9	negative selection	7381825
56167043	56167066	8	+	27260156	MHHES1	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.035538018838404045	[560]	[935,455,682,440]	0	hSpCas9	negative selection	7381826
56168193	56168216	8	+	27260156	MHHES1	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.37498657237826705	[152]	[213,339,208,152]	6	hSpCas9	negative selection	7381827
56168208	56168231	8	-	27260156	MHHES1	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.32576339580136027	[208]	[430,327,284,176]	6	hSpCas9	negative selection	7446077
56167148	56167171	8	+	27260156	MHHES1	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.4395815989245258	[358]	[449,585,629,514]	7	hSpCas9	negative selection	7446078
56167303	56167326	8	-	27260156	MHHES1	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.03263647574982431	[338]	[364,399,408,323]	0	hSpCas9	negative selection	7446079
56167167	56167190	8	-	27260156	MEWO	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.3535180467770182	[568]	[479,439,341]	-6	hSpCas9	negative selection	7503076
56167043	56167066	8	+	27260156	MEWO	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.08978633030559852	[560]	[528,569,386]	-2	hSpCas9	negative selection	7503077
56168193	56168216	8	+	27260156	MEWO	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.46525087723385594	[152]	[270,200,134]	8	hSpCas9	negative selection	7503078
56168208	56168231	8	-	27260156	MEWO	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.3301840291972524	[208]	[305,257,184]	7	hSpCas9	negative selection	7567328
56167148	56167171	8	+	27260156	MEWO	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.06986467256002726	[358]	[303,375,367]	1	hSpCas9	negative selection	7567329
56167303	56167326	8	-	27260156	MEWO	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.20284498152440378	[338]	[231,309,275]	-4	hSpCas9	negative selection	7567330
56167167	56167190	8	-	27260156	LNCAPCLONEFGC	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.30016013941917374	[568]	[328,357,499,504]	-5	hSpCas9	negative selection	7624327
56167043	56167066	8	+	27260156	LNCAPCLONEFGC	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.29781062402125325	[560]	[746,674,599,466]	5	hSpCas9	negative selection	7624328
56168193	56168216	8	+	27260156	LNCAPCLONEFGC	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.6259122818576545	[152]	[213,204,166,262]	8	hSpCas9	negative selection	7624329
56168208	56168231	8	-	27260156	LNCAPCLONEFGC	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.6535491765896849	[208]	[265,319,282,318]	9	hSpCas9	negative selection	7688579
56167148	56167171	8	+	27260156	LNCAPCLONEFGC	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.3191340374113567	[358]	[529,281,463,360]	5	hSpCas9	negative selection	7688580
56167303	56167326	8	-	27260156	LNCAPCLONEFGC	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.342975264028729	[338]	[210,138,324,312]	-5	hSpCas9	negative selection	7688581
56167167	56167190	8	-	27260156	PANC0327	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	0.255413932496948	[568]	[675,639,399,697]	4	hSpCas9	negative selection	7745578
56167043	56167066	8	+	27260156	PANC0327	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.18016652869351146	[560]	[738,605,380,540]	2	hSpCas9	negative selection	7745579
56168193	56168216	8	+	27260156	PANC0327	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.016812569258983334	[152]	[120,156,90,176]	0	hSpCas9	negative selection	7745580
56168208	56168231	8	-	27260156	PANC0327	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.7437585905939408	[208]	[283,406,352,184]	9	hSpCas9	negative selection	7809830
56167148	56167171	8	+	27260156	PANC0327	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.7423784636203219	[358]	[923,531,406,302]	9	hSpCas9	negative selection	7809831
56167303	56167326	8	-	27260156	PANC0327	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.4572192022188092	[338]	[272,315,75,203]	-6	hSpCas9	negative selection	7809832
56167167	56167190	8	-	27260156	NCIH2009	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.3958696178135215	[568]	[824,672,355]	-5	hSpCas9	negative selection	7866829
56167043	56167066	8	+	27260156	NCIH2009	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.39353519548578053	[560]	[896,507,444]	-5	hSpCas9	negative selection	7866830
56168193	56168216	8	+	27260156	NCIH2009	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	-0.15084511304308656	[152]	[209,233,135]	-2	hSpCas9	negative selection	7866831
56168208	56168231	8	-	27260156	NCIH2009	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.10116798566947183	[208]	[424,269,266]	1	hSpCas9	negative selection	7931081
56167148	56167171	8	+	27260156	NCIH2009	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.25130029342849036	[358]	[683,554,568]	3	hSpCas9	negative selection	7931082
56167303	56167326	8	-	27260156	NCIH2009	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.5118040535549138	[338]	[426,316,270]	-6	hSpCas9	negative selection	7931083
56167167	56167190	8	-	27260156	NCIH1373	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	0.25097735346320615	[568]	[1101,514,534,256]	2	hSpCas9	negative selection	7988080
56167043	56167066	8	+	27260156	NCIH1373	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.2666167828961934	[560]	[1167,721,700,126]	2	hSpCas9	negative selection	7988081
56168193	56168216	8	+	27260156	NCIH1373	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.9815992506439306	[152]	[116,373,183,173]	8	hSpCas9	negative selection	7988082
56168208	56168231	8	-	27260156	NCIH1373	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.40511642501248835	[208]	[159,201,481,100]	4	hSpCas9	negative selection	8052332
56167148	56167171	8	+	27260156	NCIH1373	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.4023786975422529	[358]	[332,528,516,190]	4	hSpCas9	negative selection	8052333
56167303	56167326	8	-	27260156	NCIH1373	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.44737055554436084	[338]	[348,363,542,215]	4	hSpCas9	negative selection	8052334
56167167	56167190	8	-	27260156	PATU8902	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-1.3037375870286039	[568]	[249,341,320,375]	-8	hSpCas9	negative selection	8109331
56167043	56167066	8	+	27260156	PATU8902	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.7654112737951534	[560]	[725,662,197,292]	-6	hSpCas9	negative selection	8109332
56168193	56168216	8	+	27260156	PATU8902	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	-0.16863849460972635	[152]	[242,162,235,89]	-2	hSpCas9	negative selection	8109333
56168208	56168231	8	-	27260156	PATU8902	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.6938228782725055	[208]	[394,531,364,635]	7	hSpCas9	negative selection	8173583
56167148	56167171	8	+	27260156	PATU8902	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.5777176238108994	[358]	[923,547,985,415]	6	hSpCas9	negative selection	8173584
56167303	56167326	8	-	27260156	PATU8902	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.46466622449327943	[338]	[188,546,168,530]	-4	hSpCas9	negative selection	8173585
56167167	56167190	8	-	27260156	PANC1	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.3256075726578823	[568]	[374,462,483,267]	-5	hSpCas9	negative selection	8230582
56167043	56167066	8	+	27260156	PANC1	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.3469404762459486	[560]	[369,747,755,602]	5	hSpCas9	negative selection	8230583
56168193	56168216	8	+	27260156	PANC1	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	-0.006366997121552531	[152]	[82,197,150,107]	0	hSpCas9	negative selection	8230584
56168208	56168231	8	-	27260156	PANC1	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.16770911691670976	[208]	[92,401,226,135]	2	hSpCas9	negative selection	8294834
56167148	56167171	8	+	27260156	PANC1	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.5573945397215841	[358]	[467,497,430,423]	8	hSpCas9	negative selection	8294835
56167303	56167326	8	-	27260156	PANC1	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.3631167097060527	[338]	[214,225,234,225]	-5	hSpCas9	negative selection	8294836
56167167	56167190	8	-	27260156	PANC0813	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	0.0864410837619316	[568]	[647,821,645,714]	1	hSpCas9	negative selection	8351833
56167043	56167066	8	+	27260156	PANC0813	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.05299363436592042	[560]	[607,734,595,599]	-1	hSpCas9	negative selection	8351834
56168193	56168216	8	+	27260156	PANC0813	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.3893338311706769	[152]	[299,228,286,136]	6	hSpCas9	negative selection	8351835
56168208	56168231	8	-	27260156	PANC0813	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.4795225882733337	[208]	[468,362,176,368]	7	hSpCas9	negative selection	8416085
56167148	56167171	8	+	27260156	PANC0813	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.4325217153366992	[358]	[794,607,336,555]	7	hSpCas9	negative selection	8416086
56167303	56167326	8	-	27260156	PANC0813	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.10310229369737023	[338]	[513,280,304,393]	-2	hSpCas9	negative selection	8416087
56167167	56167190	8	-	27260156	RDES	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.3197453756574068	[568]	[491,518,545,531]	-5	hSpCas9	negative selection	8473084
56167043	56167066	8	+	27260156	RDES	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.09962635314230156	[560]	[507,810,647,823]	1	hSpCas9	negative selection	8473085
56168193	56168216	8	+	27260156	RDES	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.4357693189615348	[152]	[187,233,292,243]	7	hSpCas9	negative selection	8473086
56168208	56168231	8	-	27260156	RDES	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.3774058656713061	[208]	[253,325,302,376]	6	hSpCas9	negative selection	8537336
56167148	56167171	8	+	27260156	RDES	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.5415028027946476	[358]	[559,474,731,650]	8	hSpCas9	negative selection	8537337
56167303	56167326	8	-	27260156	RDES	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.30640356014594017	[338]	[231,265,296,508]	-5	hSpCas9	negative selection	8537338
56167167	56167190	8	-	27260156	PC3	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.557449292213364	[568]	[266,266,769,406]	-8	hSpCas9	negative selection	8594335
56167043	56167066	8	+	27260156	PC3	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.44835856239804106	[560]	[277,291,847,414]	-8	hSpCas9	negative selection	8594336
56168193	56168216	8	+	27260156	PC3	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.6830537200439551	[152]	[143,181,567,236]	9	hSpCas9	negative selection	8594337
56168208	56168231	8	-	27260156	PC3	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.7357046141587223	[208]	[242,307,671,299]	9	hSpCas9	negative selection	8658587
56167148	56167171	8	+	27260156	PC3	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.05635617732551107	[358]	[219,224,780,467]	1	hSpCas9	negative selection	8658588
56167303	56167326	8	-	27260156	PC3	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.1410362854623306	[338]	[177,309,527,324]	-3	hSpCas9	negative selection	8658589
56167167	56167190	8	-	27260156	PATU8988T	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.44693388902272324	[568]	[314,422,337,551]	-6	hSpCas9	negative selection	8715586
56167043	56167066	8	+	27260156	PATU8988T	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.4341096680145685	[560]	[361,366,310,576]	-6	hSpCas9	negative selection	8715587
56168193	56168216	8	+	27260156	PATU8988T	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.6812660649791238	[152]	[103,282,290,276]	9	hSpCas9	negative selection	8715588
56168208	56168231	8	-	27260156	PATU8988T	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.5741645111178276	[208]	[393,301,256,245]	8	hSpCas9	negative selection	8779838
56167148	56167171	8	+	27260156	PATU8988T	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.07665274960295776	[358]	[346,409,331,379]	1	hSpCas9	negative selection	8779839
56167303	56167326	8	-	27260156	PATU8988T	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.2519427414016755	[338]	[543,155,158,227]	-4	hSpCas9	negative selection	8779840
56167167	56167190	8	-	27260156	T47D	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.3289406416240953	[568]	[608,491,543,466]	-6	hSpCas9	negative selection	8836837
56167043	56167066	8	+	27260156	T47D	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.0908094526900079	[560]	[767,623,667,731]	2	hSpCas9	negative selection	8836838
56168193	56168216	8	+	27260156	T47D	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.545398742779291	[152]	[246,306,260,219]	9	hSpCas9	negative selection	8836839
56168208	56168231	8	-	27260156	T47D	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.40725611168301346	[208]	[341,243,355,356]	8	hSpCas9	negative selection	8901089
56167148	56167171	8	+	27260156	T47D	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.2656681781589688	[358]	[434,458,488,635]	5	hSpCas9	negative selection	8901090
56167303	56167326	8	-	27260156	T47D	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.35081490175789765	[338]	[279,277,316,367]	-6	hSpCas9	negative selection	8901091
56167167	56167190	8	-	27260156	SU8686	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.30205001762388484	[568]	[346,451,442,624]	-5	hSpCas9	negative selection	8958088
56167043	56167066	8	+	27260156	SU8686	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.24327729100525197	[560]	[423,426,528,515]	-4	hSpCas9	negative selection	8958089
56168193	56168216	8	+	27260156	SU8686	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.5962509565854801	[152]	[182,239,252,246]	8	hSpCas9	negative selection	8958090
56168208	56168231	8	-	27260156	SU8686	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.5837476392283953	[208]	[267,216,280,524]	8	hSpCas9	negative selection	9022340
56167148	56167171	8	+	27260156	SU8686	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.1457886413413991	[358]	[348,317,448,487]	2	hSpCas9	negative selection	9022341
56167303	56167326	8	-	27260156	SU8686	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.4180662881195837	[338]	[273,161,237,355]	-6	hSpCas9	negative selection	9022342
56167167	56167190	8	-	27260156	SKES1	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.1176537729671247	[568]	[739,502,558,334]	-3	hSpCas9	negative selection	9079339
56167043	56167066	8	+	27260156	SKES1	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.09539870051778707	[560]	[552,703,462,409]	-2	hSpCas9	negative selection	9079340
56168193	56168216	8	+	27260156	SKES1	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.5630035038861854	[152]	[198,300,236,173]	9	hSpCas9	negative selection	9079341
56168208	56168231	8	-	27260156	SKES1	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.19735325965232298	[208]	[194,313,302,153]	4	hSpCas9	negative selection	9143591
56167148	56167171	8	+	27260156	SKES1	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.22348458805099225	[358]	[496,433,467,295]	5	hSpCas9	negative selection	9143592
56167303	56167326	8	-	27260156	SKES1	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.28644535351060896	[338]	[329,257,323,206]	-6	hSpCas9	negative selection	9143593
56167167	56167190	8	-	27260156	TOV112D	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	0.032949341194302095	[568]	[505,815,655,408]	0	hSpCas9	negative selection	9200590
56167043	56167066	8	+	27260156	TOV112D	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	0.2787213991015063	[560]	[433,1428,473,554]	5	hSpCas9	negative selection	9200591
56168193	56168216	8	+	27260156	TOV112D	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.3920793148369397	[152]	[150,275,144,244]	7	hSpCas9	negative selection	9200592
56168208	56168231	8	-	27260156	TOV112D	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.5939277667890017	[208]	[386,430,179,299]	9	hSpCas9	negative selection	9264842
56167148	56167171	8	+	27260156	TOV112D	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.20342992848895608	[358]	[328,558,386,408]	4	hSpCas9	negative selection	9264843
56167303	56167326	8	-	27260156	TOV112D	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	0.2571106260915685	[338]	[355,571,321,408]	5	hSpCas9	negative selection	9264844
56167167	56167190	8	-	27260156	TC71	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.3912904318751174	[568]	[475,441,401,546]	-8	hSpCas9	negative selection	9321841
56167043	56167066	8	+	27260156	TC71	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.19881599501557407	[560]	[486,480,581,545]	-5	hSpCas9	negative selection	9321842
56168193	56168216	8	+	27260156	TC71	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	-0.06317949168309056	[152]	[179,146,151,147]	-2	hSpCas9	negative selection	9321843
56168208	56168231	8	-	27260156	TC71	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.12616373345482335	[208]	[203,208,273,293]	3	hSpCas9	negative selection	9386093
56167148	56167171	8	+	27260156	TC71	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	-0.052071023634897406	[358]	[390,365,353,373]	-1	hSpCas9	negative selection	9386094
56167303	56167326	8	-	27260156	TC71	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.5781055678293217	[338]	[245,200,274,250]	-9	hSpCas9	negative selection	9386095
56167167	56167190	8	-	27260156	TC32	viability	AGTGCGAACATTGTGATCGCCGG	PLAG1	ENSG00000181690	-0.3407917408587168	[568]	[414,454,347,416]	-6	hSpCas9	negative selection	9443092
56167043	56167066	8	+	27260156	TC32	viability	TCTTCTTCATATGTCGAGTCAGG	PLAG1	ENSG00000181690	-0.3955257996537752	[560]	[371,264,529,495]	-6	hSpCas9	negative selection	9443093
56168193	56168216	8	+	27260156	TC32	viability	CCACGCTTACGTTTCCCTGAAGG	PLAG1	ENSG00000181690	0.4002347044960459	[152]	[195,130,166,275]	7	hSpCas9	negative selection	9443094
56168208	56168231	8	-	27260156	TC32	viability	GATACCCAGAAAGTCCCTTCAGG	PLAG1	ENSG00000181690	0.13320419130747863	[208]	[144,202,278,247]	2	hSpCas9	negative selection	9507344
56167148	56167171	8	+	27260156	TC32	viability	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	-0.1337095921214846	[358]	[303,210,387,362]	-2	hSpCas9	negative selection	9507345
56167303	56167326	8	-	27260156	TC32	viability	GCCTTGCATGCCGCAACAAGTGG	PLAG1	ENSG00000181690	-0.7084179862943614	[338]	[119,162,272,250]	-8	hSpCas9	negative selection	9507346
56166252	56166275	8	+	27869803	HPAFII	viability after 27 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	0.6336141889900186	[179]	[88,194,NaN]	5	hSpCas9	negative selection	9602893
56166649	56166672	8	-	27869803	HPAFII	viability after 27 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.7711739815479189	[174]	[60,47,NaN]	-5	hSpCas9	negative selection	9602894
56167148	56167171	8	+	27869803	HPAFII	viability after 27 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.5796571509553965	[307]	[271,216,NaN]	5	hSpCas9	negative selection	9602895
56167151	56167174	8	-	27869803	HPAFII	viability after 27 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.41698594590284394	[347]	[282,211,NaN]	3	hSpCas9	negative selection	9602896
56168243	56168266	8	+	27869803	HPAFII	viability after 27 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	0.9528287330235253	[344]	[391,316,NaN]	7	hSpCas9	negative selection	9602897
56166252	56166275	8	+	27869803	HPAFII	viability after 15 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	0.04334392257015235	[179]	[215,188,NaN]	0	hSpCas9	negative selection	9685342
56166649	56166672	8	-	27869803	HPAFII	viability after 15 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.5106174959334139	[174]	[123,136,NaN]	-5	hSpCas9	negative selection	9685343
56167148	56167171	8	+	27869803	HPAFII	viability after 15 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.7330320473587375	[307]	[646,489,NaN]	7	hSpCas9	negative selection	9685344
56167151	56167174	8	-	27869803	HPAFII	viability after 15 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.179655440966158	[347]	[467,395,NaN]	2	hSpCas9	negative selection	9685345
56168243	56168266	8	+	27869803	HPAFII	viability after 15 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	0.23721427876605838	[344]	[568,354,NaN]	2	hSpCas9	negative selection	9685346
56166252	56166275	8	+	27869803	ASPC1	viability after 36 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	-0.6096269074857719	[376]	[179,91,14]	-6	hSpCas9	negative selection	9767791
56166649	56166672	8	-	27869803	ASPC1	viability after 36 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.1467836363723663	[522]	[220,141,141]	-1	hSpCas9	negative selection	9767792
56167148	56167171	8	+	27869803	ASPC1	viability after 36 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.4522781344059299	[1100]	[598,841,217]	4	hSpCas9	negative selection	9767793
56167151	56167174	8	-	27869803	ASPC1	viability after 36 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.6130907273636915	[792]	[429,482,366]	6	hSpCas9	negative selection	9767794
56168243	56168266	8	+	27869803	ASPC1	viability after 36 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	-0.415467790675028	[846]	[431,131,142]	-4	hSpCas9	negative selection	9767795
56166252	56166275	8	+	27869803	PATU8988S	viability after 35 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	-0.18122982438301827	[324]	[89,140,NaN]	-2	hSpCas9	negative selection	9850240
56166649	56166672	8	-	27869803	PATU8988S	viability after 35 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.2409285684498012	[414]	[112,169,NaN]	-3	hSpCas9	negative selection	9850241
56167148	56167171	8	+	27869803	PATU8988S	viability after 35 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	-0.04025693693689858	[963]	[406,347,NaN]	0	hSpCas9	negative selection	9850242
56167151	56167174	8	-	27869803	PATU8988S	viability after 35 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.388413722354411	[607]	[331,308,NaN]	4	hSpCas9	negative selection	9850243
56168243	56168266	8	+	27869803	PATU8988S	viability after 35 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	-0.6827388940781083	[649]	[201,123,NaN]	-6	hSpCas9	negative selection	9850244
56166252	56166275	8	+	27869803	PATU8988S	viability after 31 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	-0.26734009441077733	[324]	[64,161,NaN]	-3	hSpCas9	negative selection	9932689
56166649	56166672	8	-	27869803	PATU8988S	viability after 31 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	0.024151924304199712	[414]	[129,216,NaN]	0	hSpCas9	negative selection	9932690
56167148	56167171	8	+	27869803	PATU8988S	viability after 31 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	-0.09311581736201713	[963]	[373,342,NaN]	-1	hSpCas9	negative selection	9932691
56167151	56167174	8	-	27869803	PATU8988S	viability after 31 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.3746599151877846	[607]	[345,273,NaN]	4	hSpCas9	negative selection	9932692
56168243	56168266	8	+	27869803	PATU8988S	viability after 31 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	-0.28768787663802997	[649]	[243,171,NaN]	-3	hSpCas9	negative selection	9932693
56166252	56166275	8	+	27869803	HPAFII	viability after 35 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	1.1534067897388538	[179]	[62,359,NaN]	7	hSpCas9	negative selection	10015138
56166649	56166672	8	-	27869803	HPAFII	viability after 35 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.3179304964806048	[174]	[95,42,NaN]	-2	hSpCas9	negative selection	10015139
56167148	56167171	8	+	27869803	HPAFII	viability after 35 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.4365363215044065	[307]	[250,165,NaN]	3	hSpCas9	negative selection	10015140
56167151	56167174	8	-	27869803	HPAFII	viability after 35 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.5599548484733188	[347]	[286,228,NaN]	3	hSpCas9	negative selection	10015141
56168243	56168266	8	+	27869803	HPAFII	viability after 35 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	1.2886194152371107	[344]	[357,503,NaN]	8	hSpCas9	negative selection	10015142
56166252	56166275	8	+	27869803	HPAFII	viability after 31 days	AGCTTGATGGAAACGTGGGAGGG	PLAG1	ENSG00000181690	0.9348291853572008	[179]	[83,311,NaN]	7	hSpCas9	negative selection	10097587
56166649	56166672	8	-	27869803	HPAFII	viability after 31 days	TACCTGATGGAGTTACAAGGTGG	PLAG1	ENSG00000181690	-0.25564558353393185	[174]	[76,87,NaN]	-2	hSpCas9	negative selection	10097588
56167148	56167171	8	+	27869803	HPAFII	viability after 31 days	CATCCTTTCGGGTGTAGAACCGG	PLAG1	ENSG00000181690	0.5994175609632344	[307]	[225,300,NaN]	4	hSpCas9	negative selection	10097589
56167151	56167174	8	-	27869803	HPAFII	viability after 31 days	TCGCCGGTTCTACACCCGAAAGG	PLAG1	ENSG00000181690	0.7980293163640235	[347]	[452,215,NaN]	6	hSpCas9	negative selection	10097590
56168243	56168266	8	+	27869803	HPAFII	viability after 31 days	CAAATCACCAGGAATGACAGTGG	PLAG1	ENSG00000181690	1.0692187470059498	[344]	[322,496,NaN]	7	hSpCas9	negative selection	10097591
56167001	56167024	8	-	28162770	P31FUJ	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.4688565210158748	[363]	[591]	5	hSpCas9	negative selection	10212308
56167112	56167135	8	-	28162770	P31FUJ	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	0.12831974933718504	[442]	[568]	1	hSpCas9	negative selection	10212309
56166926	56166949	8	+	28162770	P31FUJ	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.5667707057459649	[238]	[415]	6	hSpCas9	negative selection	10212310
56166248	56166271	8	+	28162770	P31FUJ	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	0.2266294142229186	[39]	[54]	2	hSpCas9	negative selection	10212311
56167293	56167316	8	+	28162770	P31FUJ	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-0.15598660736354772	[255]	[269]	-1	hSpCas9	negative selection	10212312
56167225	56167248	8	-	28162770	P31FUJ	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	-0.11149590819224486	[113]	[123]	-1	hSpCas9	negative selection	10212313
56167169	56167192	8	+	28162770	P31FUJ	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.10683261317680032	[273]	[298]	-1	hSpCas9	negative selection	10212314
56167130	56167153	8	-	28162770	P31FUJ	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.2537118082186832	[378]	[530]	2	hSpCas9	negative selection	10212315
56167085	56167108	8	+	28162770	P31FUJ	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	0.17024274832817188	[452]	[598]	1	hSpCas9	negative selection	10212316
56167210	56167233	8	-	28162770	P31FUJ	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	0.3456025802846153	[293]	[438]	4	hSpCas9	negative selection	10212317
56167001	56167024	8	-	28162770	TF1	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	NaN	[NaN]	[395]	1	hSpCas9	negative selection	10381674
56167112	56167135	8	-	28162770	TF1	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	NaN	[NaN]	[662]	1	hSpCas9	negative selection	10381675
56166926	56166949	8	+	28162770	TF1	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	NaN	[NaN]	[218]	1	hSpCas9	negative selection	10381676
56166248	56166271	8	+	28162770	TF1	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10381677
56167293	56167316	8	+	28162770	TF1	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	NaN	[NaN]	[231]	1	hSpCas9	negative selection	10381678
56167225	56167248	8	-	28162770	TF1	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	NaN	[NaN]	[106]	1	hSpCas9	negative selection	10381679
56167169	56167192	8	+	28162770	TF1	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10381680
56167130	56167153	8	-	28162770	TF1	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	NaN	[NaN]	[281]	1	hSpCas9	negative selection	10381681
56167085	56167108	8	+	28162770	TF1	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	NaN	[NaN]	[432]	1	hSpCas9	negative selection	10381682
56167210	56167233	8	-	28162770	TF1	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	NaN	[NaN]	[143]	1	hSpCas9	negative selection	10381683
56167001	56167024	8	-	28162770	SKM1	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.5930358012568383	[110]	[295]	6	hSpCas9	negative selection	10551040
56167112	56167135	8	-	28162770	SKM1	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	1.0922684279521104	[90]	[342]	8	hSpCas9	negative selection	10551041
56166926	56166949	8	+	28162770	SKM1	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.18771345681120616	[73]	[148]	1	hSpCas9	negative selection	10551042
56166248	56166271	8	+	28162770	SKM1	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	-1.0146467759644016	[15]	[13]	-6	hSpCas9	negative selection	10551043
56167293	56167316	8	+	28162770	SKM1	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	0.19762710872692707	[72]	[147]	2	hSpCas9	negative selection	10551044
56167225	56167248	8	-	28162770	SKM1	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	-1.0255350921071378	[37]	[32]	-6	hSpCas9	negative selection	10551045
56167169	56167192	8	+	28162770	SKM1	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.29148698132322576	[53]	[77]	-2	hSpCas9	negative selection	10551046
56167130	56167153	8	-	28162770	SKM1	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.7618807055844347	[93]	[97]	-5	hSpCas9	negative selection	10551047
56167085	56167108	8	+	28162770	SKM1	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	0.6919214657672957	[110]	[316]	6	hSpCas9	negative selection	10551048
56167210	56167233	8	-	28162770	SKM1	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	0.10548580219362656	[50]	[96]	1	hSpCas9	negative selection	10551049
56167001	56167024	8	-	28162770	SKM1	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.5930358012568383	[110]	[295]	6	hSpCas9	negative selection	10720406
56167112	56167135	8	-	28162770	SKM1	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	1.0922684279521104	[90]	[342]	8	hSpCas9	negative selection	10720407
56166926	56166949	8	+	28162770	SKM1	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.18771345681120616	[73]	[148]	1	hSpCas9	negative selection	10720408
56166248	56166271	8	+	28162770	SKM1	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	-1.0146467759644016	[15]	[13]	-6	hSpCas9	negative selection	10720409
56167293	56167316	8	+	28162770	SKM1	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	0.19762710872692707	[72]	[147]	2	hSpCas9	negative selection	10720410
56167225	56167248	8	-	28162770	SKM1	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	-1.0255350921071378	[37]	[32]	-6	hSpCas9	negative selection	10720411
56167169	56167192	8	+	28162770	SKM1	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.29148698132322576	[53]	[77]	-2	hSpCas9	negative selection	10720412
56167130	56167153	8	-	28162770	SKM1	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.7618807055844347	[93]	[97]	-5	hSpCas9	negative selection	10720413
56167085	56167108	8	+	28162770	SKM1	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	0.6919214657672957	[110]	[316]	6	hSpCas9	negative selection	10720414
56167210	56167233	8	-	28162770	SKM1	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	0.10548580219362656	[50]	[96]	1	hSpCas9	negative selection	10720415
56167001	56167024	8	-	28162770	PL21	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	-0.6367797651104226	[492]	[137]	-4	hSpCas9	negative selection	10889772
56167112	56167135	8	-	28162770	PL21	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	0.46317402032311394	[314]	[188]	4	hSpCas9	negative selection	10889773
56166926	56166949	8	+	28162770	PL21	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.35423964876994996	[274]	[152]	3	hSpCas9	negative selection	10889774
56166248	56166271	8	+	28162770	PL21	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	-0.4569726719876712	[40]	[12]	-3	hSpCas9	negative selection	10889775
56167293	56167316	8	+	28162770	PL21	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-0.6792702446970915	[194]	[52]	-5	hSpCas9	negative selection	10889776
56167225	56167248	8	-	28162770	PL21	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	1.3135976642726042	[109]	[118]	9	hSpCas9	negative selection	10889777
56167169	56167192	8	+	28162770	PL21	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	1.139839104221506	[170]	[163]	8	hSpCas9	negative selection	10889778
56167130	56167153	8	-	28162770	PL21	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.3874181826819007	[201]	[114]	3	hSpCas9	negative selection	10889779
56167085	56167108	8	+	28162770	PL21	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	0.33198427050538126	[417]	[228]	3	hSpCas9	negative selection	10889780
56167210	56167233	8	-	28162770	PL21	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	-0.40189639959077766	[169]	[55]	-3	hSpCas9	negative selection	10889781
56167001	56167024	8	-	28162770	P31FUJ	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.4688565210158748	[363]	[591]	5	hSpCas9	negative selection	11059138
56167112	56167135	8	-	28162770	P31FUJ	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	0.12831974933718504	[442]	[568]	1	hSpCas9	negative selection	11059139
56166926	56166949	8	+	28162770	P31FUJ	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.5667707057459649	[238]	[415]	6	hSpCas9	negative selection	11059140
56166248	56166271	8	+	28162770	P31FUJ	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	0.2266294142229186	[39]	[54]	2	hSpCas9	negative selection	11059141
56167293	56167316	8	+	28162770	P31FUJ	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-0.15598660736354772	[255]	[269]	-1	hSpCas9	negative selection	11059142
56167225	56167248	8	-	28162770	P31FUJ	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	-0.11149590819224486	[113]	[123]	-1	hSpCas9	negative selection	11059143
56167169	56167192	8	+	28162770	P31FUJ	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.10683261317680032	[273]	[298]	-1	hSpCas9	negative selection	11059144
56167130	56167153	8	-	28162770	P31FUJ	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.2537118082186832	[378]	[530]	2	hSpCas9	negative selection	11059145
56167085	56167108	8	+	28162770	P31FUJ	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	0.17024274832817188	[452]	[598]	1	hSpCas9	negative selection	11059146
56167210	56167233	8	-	28162770	P31FUJ	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	0.3456025802846153	[293]	[438]	4	hSpCas9	negative selection	11059147
56167001	56167024	8	-	28162770	OCIAML5	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.5622435802568195	[247]	[660]	5	hSpCas9	negative selection	11228504
56167112	56167135	8	-	28162770	OCIAML5	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	0.3582022913899614	[238]	[552]	3	hSpCas9	negative selection	11228505
56166926	56166949	8	+	28162770	OCIAML5	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.9671299638381237	[103]	[366]	8	hSpCas9	negative selection	11228506
56166248	56166271	8	+	28162770	OCIAML5	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	0.08081923327746598	[54]	[104]	0	hSpCas9	negative selection	11228507
56167293	56167316	8	+	28162770	OCIAML5	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-0.49484972597349536	[209]	[268]	-3	hSpCas9	negative selection	11228508
56167225	56167248	8	-	28162770	OCIAML5	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	-0.34305292337613946	[77]	[110]	-2	hSpCas9	negative selection	11228509
56167169	56167192	8	+	28162770	OCIAML5	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	0.15273441539982424	[149]	[300]	1	hSpCas9	negative selection	11228510
56167130	56167153	8	-	28162770	OCIAML5	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.36942557272661325	[228]	[533]	3	hSpCas9	negative selection	11228511
56167085	56167108	8	+	28162770	OCIAML5	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	-0.11232922744773721	[311]	[520]	-1	hSpCas9	negative selection	11228512
56167210	56167233	8	-	28162770	OCIAML5	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	0.5828704858525517	[107]	[291]	5	hSpCas9	negative selection	11228513
56167001	56167024	8	-	28162770	EOL1	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.3454721139262924	[855]	[572]	3	hSpCas9	negative selection	11397870
56167112	56167135	8	-	28162770	EOL1	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	-0.11021764659014205	[419]	[204]	-1	hSpCas9	negative selection	11397871
56166926	56166949	8	+	28162770	EOL1	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.6081437231548092	[390]	[313]	5	hSpCas9	negative selection	11397872
56166248	56166271	8	+	28162770	EOL1	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	-1.4601160786647902	[93]	[17]	-7	hSpCas9	negative selection	11397873
56167293	56167316	8	+	28162770	EOL1	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	0.1412038233578382	[431]	[250]	1	hSpCas9	negative selection	11397874
56167225	56167248	8	-	28162770	EOL1	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	0.47656617367677545	[250]	[183]	4	hSpCas9	negative selection	11397875
56167169	56167192	8	+	28162770	EOL1	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.7574821471107865	[291]	[90]	-5	hSpCas9	negative selection	11397876
56167130	56167153	8	-	28162770	EOL1	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.2320425913701672	[349]	[156]	-2	hSpCas9	negative selection	11397877
56167085	56167108	8	+	28162770	EOL1	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	0.7765236846854344	[522]	[471]	6	hSpCas9	negative selection	11397878
56167210	56167233	8	-	28162770	EOL1	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	-0.36150328698823125	[277]	[113]	-3	hSpCas9	negative selection	11397879
56167001	56167024	8	-	28162770	MOLM13	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	-0.11933972614852228	[636]	[423]	0	hSpCas9	negative selection	11567236
56167112	56167135	8	-	28162770	MOLM13	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	-0.27167332410766654	[555]	[332]	-2	hSpCas9	negative selection	11567237
56166926	56166949	8	+	28162770	MOLM13	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	-0.2120215232318401	[313]	[195]	-1	hSpCas9	negative selection	11567238
56166248	56166271	8	+	28162770	MOLM13	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	-0.8719606213400459	[80]	[31]	-5	hSpCas9	negative selection	11567239
56167293	56167316	8	+	28162770	MOLM13	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	0.5334777231721557	[300]	[314]	4	hSpCas9	negative selection	11567240
56167225	56167248	8	-	28162770	MOLM13	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	-0.3492465613056106	[221]	[125]	-2	hSpCas9	negative selection	11567241
56167169	56167192	8	+	28162770	MOLM13	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.7403819315472164	[304]	[131]	-4	hSpCas9	negative selection	11567242
56167130	56167153	8	-	28162770	MOLM13	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-2.0478104567394637	[365]	[63]	-7	hSpCas9	negative selection	11567243
56167085	56167108	8	+	28162770	MOLM13	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	-1.4278352964116132	[546]	[146]	-6	hSpCas9	negative selection	11567244
56167210	56167233	8	-	28162770	MOLM13	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	-1.3971810383693124	[254]	[69]	-6	hSpCas9	negative selection	11567245
56167001	56167024	8	-	28162770	HEL	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.4448710077692879	[592]	[516]	4	hSpCas9	negative selection	11736602
56167112	56167135	8	-	28162770	HEL	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	1.0090105042839372	[345]	[445]	8	hSpCas9	negative selection	11736603
56166926	56166949	8	+	28162770	HEL	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.31488590315588927	[304]	[242]	2	hSpCas9	negative selection	11736604
56166248	56166271	8	+	28162770	HEL	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	1.2130545567571118	[65]	[97]	9	hSpCas9	negative selection	11736605
56167293	56167316	8	+	28162770	HEL	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-0.026719942807572783	[333]	[209]	0	hSpCas9	negative selection	11736606
56167225	56167248	8	-	28162770	HEL	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	0.46701154449151094	[217]	[192]	4	hSpCas9	negative selection	11736607
56167169	56167192	8	+	28162770	HEL	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.40535545620068814	[243]	[117]	-3	hSpCas9	negative selection	11736608
56167130	56167153	8	-	28162770	HEL	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.00402895319427099	[309]	[197]	0	hSpCas9	negative selection	11736609
56167085	56167108	8	+	28162770	HEL	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	-0.3326591947665649	[406]	[206]	-2	hSpCas9	negative selection	11736610
56167210	56167233	8	-	28162770	HEL	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	-0.22529582779113816	[260]	[142]	-2	hSpCas9	negative selection	11736611
56167001	56167024	8	-	28162770	MV411	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.7187986567912346	[426]	[591]	6	hSpCas9	negative selection	11905968
56167112	56167135	8	-	28162770	MV411	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	0.3099467522607863	[270]	[282]	2	hSpCas9	negative selection	11905969
56166926	56166949	8	+	28162770	MV411	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.5135778674843907	[231]	[278]	4	hSpCas9	negative selection	11905970
56166248	56166271	8	+	28162770	MV411	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	-1.8400252904675642	[50]	[11]	-8	hSpCas9	negative selection	11905971
56167293	56167316	8	+	28162770	MV411	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	0.1178022703661799	[255]	[233]	1	hSpCas9	negative selection	11905972
56167225	56167248	8	-	28162770	MV411	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	-0.16375788220167442	[124]	[93]	-1	hSpCas9	negative selection	11905973
56167169	56167192	8	+	28162770	MV411	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.4846292439705918	[195]	[117]	-4	hSpCas9	negative selection	11905974
56167130	56167153	8	-	28162770	MV411	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.614219881454398	[227]	[293]	5	hSpCas9	negative selection	11905975
56167085	56167108	8	+	28162770	MV411	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	-0.43148075801555874	[340]	[212]	-3	hSpCas9	negative selection	11905976
56167210	56167233	8	-	28162770	MV411	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	-0.46783297228411186	[219]	[133]	-3	hSpCas9	negative selection	11905977
56167001	56167024	8	-	28162770	MONOMAC1	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.6849411785834774	[330]	[609]	6	hSpCas9	negative selection	12075334
56167112	56167135	8	-	28162770	MONOMAC1	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	0.37993286290807204	[180]	[269]	4	hSpCas9	negative selection	12075335
56166926	56166949	8	+	28162770	MONOMAC1	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.8670934903601619	[153]	[321]	7	hSpCas9	negative selection	12075336
56166248	56166271	8	+	28162770	MONOMAC1	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	-0.3303033779230178	[33]	[30]	-3	hSpCas9	negative selection	12075337
56167293	56167316	8	+	28162770	MONOMAC1	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	0.20735340801978164	[135]	[179]	2	hSpCas9	negative selection	12075338
56167225	56167248	8	-	28162770	MONOMAC1	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	0.9693215393625665	[44]	[100]	8	hSpCas9	negative selection	12075339
56167169	56167192	8	+	28162770	MONOMAC1	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	0.3611729260559172	[126]	[186]	3	hSpCas9	negative selection	12075340
56167130	56167153	8	-	28162770	MONOMAC1	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-0.17455283290817458	[190]	[193]	-1	hSpCas9	negative selection	12075341
56167085	56167108	8	+	28162770	MONOMAC1	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	0.5688717029176119	[226]	[385]	5	hSpCas9	negative selection	12075342
56167210	56167233	8	-	28162770	MONOMAC1	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	-0.20760608876974102	[136]	[135]	-2	hSpCas9	negative selection	12075343
56167001	56167024	8	-	28162770	OCIAML2	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	0.0016030756182254802	[101]	[565]	0	hSpCas9	negative selection	12244700
56167112	56167135	8	-	28162770	OCIAML2	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	0.3844218388467393	[50]	[368]	3	hSpCas9	negative selection	12244701
56166926	56166949	8	+	28162770	OCIAML2	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	0.6735649011067335	[43]	[388]	6	hSpCas9	negative selection	12244702
56166248	56166271	8	+	28162770	OCIAML2	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	-0.956056652412403	[13]	[39]	-6	hSpCas9	negative selection	12244703
56167293	56167316	8	+	28162770	OCIAML2	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	0.8626432432392105	[37]	[382]	8	hSpCas9	negative selection	12244704
56167225	56167248	8	-	28162770	OCIAML2	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	-0.622632918687211	[24]	[89]	-5	hSpCas9	negative selection	12244705
56167169	56167192	8	+	28162770	OCIAML2	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-0.5202118540927215	[36]	[142]	-4	hSpCas9	negative selection	12244706
56167130	56167153	8	-	28162770	OCIAML2	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	0.41201322411968	[39]	[294]	4	hSpCas9	negative selection	12244707
56167085	56167108	8	+	28162770	OCIAML2	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	0.14696367971896163	[50]	[312]	1	hSpCas9	negative selection	12244708
56167210	56167233	8	-	28162770	OCIAML2	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	0.22980989289893097	[35]	[233]	2	hSpCas9	negative selection	12244709
56167001	56167024	8	-	28162770	OCIAML3	viability	GAAGGTCAAAACAGAACCAGTGG	PLAG1	ENSG00000181690	-0.37677692410349417	[119]	[278]	-3	hSpCas9	negative selection	12414066
56167112	56167135	8	-	28162770	OCIAML3	viability	GGTGGTGCACACTGGAAGAAAGG	PLAG1	ENSG00000181690	-0.5338866478865922	[93]	[195]	-4	hSpCas9	negative selection	12414067
56166926	56166949	8	+	28162770	OCIAML3	viability	AAGGTAAGGACATCACCGGAAGG	PLAG1	ENSG00000181690	-0.7498785512089264	[82]	[148]	-5	hSpCas9	negative selection	12414068
56166248	56166271	8	+	28162770	OCIAML3	viability	GAAAAGCTTGATGGAAACGTGGG	PLAG1	ENSG00000181690	-2.594007640324163	[23]	[11]	-9	hSpCas9	negative selection	12414069
56167293	56167316	8	+	28162770	OCIAML3	viability	GGTGAGGTCACCACTTGTTGCGG	PLAG1	ENSG00000181690	-0.6051481979293635	[64]	[128]	-4	hSpCas9	negative selection	12414070
56167225	56167248	8	-	28162770	OCIAML3	viability	GAGCACCTTAAATCTCATGCAGG	PLAG1	ENSG00000181690	0.9038981261277699	[36]	[208]	7	hSpCas9	negative selection	12414071
56167169	56167192	8	+	28162770	OCIAML3	viability	GGCGATCACAATGTTCGCACTGG	PLAG1	ENSG00000181690	-2.0011830218300366	[60]	[45]	-8	hSpCas9	negative selection	12414072
56167130	56167153	8	-	28162770	OCIAML3	viability	GGATGTCCGGAGACACATGGTGG	PLAG1	ENSG00000181690	-1.4013625623817674	[83]	[95]	-7	hSpCas9	negative selection	12414073
56167085	56167108	8	+	28162770	OCIAML3	viability	TCTGTGCACAATACTGACAGAGG	PLAG1	ENSG00000181690	-1.2213487433158712	[94]	[122]	-7	hSpCas9	negative selection	12414074
56167210	56167233	8	-	28162770	OCIAML3	viability	CATGCAGGCAAGTCGTCTGGTGG	PLAG1	ENSG00000181690	-1.120076451991751	[53]	[74]	-7	hSpCas9	negative selection	12414075