Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5325
• Symbol: PLAGL1
• Description: PLAG1 like zinc finger 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PLAGL1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
143941935	143941958	6	+	26472758	Jiyoye	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	5.494638222756212	[0]	[33]	9	hSpCas9	negative selection	121713
143942275	143942298	6	+	26472758	Jiyoye	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	0.6813503449448675	[85]	[103]	5	hSpCas9	negative selection	121714
143941924	143941947	6	+	26472758	Jiyoye	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-2.4607210824867813	[72]	[9]	-9	hSpCas9	negative selection	121715
143942473	143942496	6	-	26472758	Jiyoye	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	0.5908163760652139	[220]	[250]	4	hSpCas9	negative selection	121716
143942308	143942331	6	-	26472758	Jiyoye	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	1.6295678028423213	[35]	[83]	8	hSpCas9	negative selection	121717
143941558	143941581	6	+	26472758	Jiyoye	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.5720293934007638	[189]	[212]	4	hSpCas9	negative selection	121718
143942503	143942526	6	-	26472758	Jiyoye	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.1350958360690726	[255]	[211]	1	hSpCas9	negative selection	121719
143942437	143942460	6	+	26472758	Jiyoye	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-1.4042150537868874	[357]	[101]	-7	hSpCas9	negative selection	121720
143942399	143942422	6	+	26472758	Jiyoye	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.1261552301987171	[112]	[92]	1	hSpCas9	negative selection	121721
143942383	143942406	6	+	26472758	Jiyoye	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	-1.3842379966827094	[179]	[51]	-7	hSpCas9	negative selection	121722
143941935	143941958	6	+	26472758	KBM7	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	0.7962263850228055	[158,120]	[107,117]	8	hSpCas9	negative selection	312831
143942275	143942298	6	+	26472758	KBM7	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	0.32604081923718875	[529,328]	[194,295]	3	hSpCas9	negative selection	312832
143941924	143941947	6	+	26472758	KBM7	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-2.871267476237568	[442,165]	[13,22]	-9	hSpCas9	negative selection	312833
143942473	143942496	6	-	26472758	KBM7	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	0.3781126906128305	[1129,825]	[646,540]	4	hSpCas9	negative selection	312834
143942308	143942331	6	-	26472758	KBM7	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.6485777908486245	[327,212]	[157,229]	7	hSpCas9	negative selection	312835
143941558	143941581	6	+	26472758	KBM7	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.29198446455382976	[1088,656]	[571,420]	3	hSpCas9	negative selection	312836
143942503	143942526	6	-	26472758	KBM7	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.25349619006507784	[1086,1374]	[831,584]	2	hSpCas9	negative selection	312837
143942437	143942460	6	+	26472758	KBM7	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-0.3043555018285815	[719,598]	[240,257]	-3	hSpCas9	negative selection	312838
143942399	143942422	6	+	26472758	KBM7	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.5408969577526954	[802,652]	[557,438]	6	hSpCas9	negative selection	312839
143942383	143942406	6	+	26472758	KBM7	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	0.12341474445537247	[332,579]	[242,239]	1	hSpCas9	negative selection	312840
143941935	143941958	6	+	26472758	Raji	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	-0.6811123594326887	[75]	[10]	-5	hSpCas9	negative selection	503949
143942275	143942298	6	+	26472758	Raji	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	0.5497715227973989	[208]	[70]	5	hSpCas9	negative selection	503950
143941924	143941947	6	+	26472758	Raji	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-1.6230094048691204	[145]	[10]	-8	hSpCas9	negative selection	503951
143942473	143942496	6	-	26472758	Raji	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	0.04234000346771982	[430]	[102]	0	hSpCas9	negative selection	503952
143942308	143942331	6	-	26472758	Raji	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	-0.7995070602349192	[194]	[25]	-6	hSpCas9	negative selection	503953
143941558	143941581	6	+	26472758	Raji	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.6779386122737301	[368]	[136]	6	hSpCas9	negative selection	503954
143942503	143942526	6	-	26472758	Raji	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.5928103625438412	[559]	[195]	5	hSpCas9	negative selection	503955
143942437	143942460	6	+	26472758	Raji	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-1.1521786785533894	[497]	[51]	-7	hSpCas9	negative selection	503956
143942399	143942422	6	+	26472758	Raji	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	-0.6129308182424427	[401]	[60]	-5	hSpCas9	negative selection	503957
143942383	143942406	6	+	26472758	Raji	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	0.7892075753473446	[191]	[76]	7	hSpCas9	negative selection	503958
143941935	143941958	6	+	26472758	K562	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	-1.4336531774461907	[127]	[39]	-6	hSpCas9	negative selection	695067
143942275	143942298	6	+	26472758	K562	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	0.20931492671053092	[415]	[405]	1	hSpCas9	negative selection	695068
143941924	143941947	6	+	26472758	K562	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-6.930506954834232	[288]	[1]	-9	hSpCas9	negative selection	695069
143942473	143942496	6	-	26472758	K562	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	-0.7445766801447424	[652]	[328]	-4	hSpCas9	negative selection	695070
143942308	143942331	6	-	26472758	K562	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.2754456232870713	[275]	[281]	2	hSpCas9	negative selection	695071
143941558	143941581	6	+	26472758	K562	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	-0.14589634220116576	[674]	[514]	-1	hSpCas9	negative selection	695072
143942503	143942526	6	-	26472758	K562	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.3740650472719602	[1020]	[1116]	3	hSpCas9	negative selection	695073
143942437	143942460	6	+	26472758	K562	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-2.6522035324882447	[699]	[93]	-8	hSpCas9	negative selection	695074
143942399	143942422	6	+	26472758	K562	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	-0.481231553271925	[634]	[383]	-3	hSpCas9	negative selection	695075
143942383	143942406	6	+	26472758	K562	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	0.32899649843681134	[264]	[280]	2	hSpCas9	negative selection	695076
143941600	143941623	6	-	26627737	DLD1	viability	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-0.17027244874335726	[479]	[171,79,143]	-2	hSpCas9	negative selection	830803
143942114	143942137	6	+	26627737	DLD1	viability	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	-0.6235481373099854	[564]	[106,155,86]	-6	hSpCas9	negative selection	830804
143942326	143942349	6	+	26627737	DLD1	viability	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.10867780352642209	[269]	[67,63,98]	-1	hSpCas9	negative selection	830805
143942485	143942508	6	-	26627737	DLD1	viability	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	1.296973108362643	[52]	[31,69,23]	9	hSpCas9	negative selection	830806
143948040	143948063	6	+	26627737	DLD1	viability	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.03161034761589476	[817]	[341,145,286]	0	hSpCas9	negative selection	830807
143941600	143941623	6	-	26627737	GBM cells	viability after 5 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-0.5356638107888033	[222]	[69,94]	-7	hSpCas9	negative selection	913118
143942114	143942137	6	+	26627737	GBM cells	viability after 5 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	0.3139513741645294	[254]	[168,170]	5	hSpCas9	negative selection	913119
143942326	143942349	6	+	26627737	GBM cells	viability after 5 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.20925399549783608	[74]	[48,43]	3	hSpCas9	negative selection	913120
143942485	143942508	6	-	26627737	GBM cells	viability after 5 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.40858824830260443	[58]	[52,30]	6	hSpCas9	negative selection	913121
143948040	143948063	6	+	26627737	GBM cells	viability after 5 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.25428016149155447	[289]	[184,185]	4	hSpCas9	negative selection	913122
143941600	143941623	6	-	26627737	GBM cells	viability after 13 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-0.12552818245053282	[222]	[143,83]	-1	hSpCas9	negative selection	995433
143942114	143942137	6	+	26627737	GBM cells	viability after 13 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	0.4476890560907466	[254]	[207,172]	5	hSpCas9	negative selection	995434
143942326	143942349	6	+	26627737	GBM cells	viability after 13 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.8167109428735764	[74]	[21,23]	-7	hSpCas9	negative selection	995435
143942485	143942508	6	-	26627737	GBM cells	viability after 13 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	-0.3272828195681101	[58]	[19,29]	-4	hSpCas9	negative selection	995436
143948040	143948063	6	+	26627737	GBM cells	viability after 13 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.12685435373337645	[289]	[205,143]	1	hSpCas9	negative selection	995437
143941600	143941623	6	-	26627737	GBM cells	viability after 21 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-0.4528799322701351	[222]	[99,77]	-4	hSpCas9	negative selection	1077748
143942114	143942137	6	+	26627737	GBM cells	viability after 21 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	0.1843752631790398	[254]	[170,144]	2	hSpCas9	negative selection	1077749
143942326	143942349	6	+	26627737	GBM cells	viability after 21 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.1567409937277242	[74]	[58,32]	1	hSpCas9	negative selection	1077750
143942485	143942508	6	-	26627737	GBM cells	viability after 21 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.06845658097346163	[58]	[30,35]	0	hSpCas9	negative selection	1077751
143948040	143948063	6	+	26627737	GBM cells	viability after 21 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.1986637356039737	[289]	[196,165]	2	hSpCas9	negative selection	1077752
143941600	143941623	6	-	26627737	RPE1	viability after 9 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-0.8443338520248896	[596]	[121,80]	-6	hSpCas9	negative selection	1160063
143942114	143942137	6	+	26627737	RPE1	viability after 9 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	-0.37708848813059015	[667]	[143,182]	-3	hSpCas9	negative selection	1160064
143942326	143942349	6	+	26627737	RPE1	viability after 9 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	2.734155483464315	[87]	[150,224]	9	hSpCas9	negative selection	1160065
143942485	143942508	6	-	26627737	RPE1	viability after 9 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	2.4472853571559074	[34]	[33,92]	9	hSpCas9	negative selection	1160066
143948040	143948063	6	+	26627737	RPE1	viability after 9 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	-0.5857523801141433	[1466]	[281,336]	-4	hSpCas9	negative selection	1160067
143941600	143941623	6	-	26627737	RPE1	viability after 12 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-0.10658385900107714	[596]	[164,131]	0	hSpCas9	negative selection	1242378
143942114	143942137	6	+	26627737	RPE1	viability after 12 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	-0.2380391845352666	[667]	[225,73]	-2	hSpCas9	negative selection	1242379
143942326	143942349	6	+	26627737	RPE1	viability after 12 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	1.9597936375685523	[87]	[73,110]	8	hSpCas9	negative selection	1242380
143942485	143942508	6	-	26627737	RPE1	viability after 12 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	1.517128627395988	[34]	[6,47]	8	hSpCas9	negative selection	1242381
143948040	143948063	6	+	26627737	RPE1	viability after 12 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	-0.6288350380906484	[1466]	[284,222]	-4	hSpCas9	negative selection	1242382
143941600	143941623	6	-	26627737	RPE1	viability after 15 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-1.2881950617889912	[596]	[116,22]	-7	hSpCas9	negative selection	1324693
143942114	143942137	6	+	26627737	RPE1	viability after 15 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	-0.10080009441088092	[667]	[304,51]	0	hSpCas9	negative selection	1324694
143942326	143942349	6	+	26627737	RPE1	viability after 15 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	2.5869082968593506	[87]	[117,179]	9	hSpCas9	negative selection	1324695
143942485	143942508	6	-	26627737	RPE1	viability after 15 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.8432240073046877	[34]	[2,31]	5	hSpCas9	negative selection	1324696
143948040	143948063	6	+	26627737	RPE1	viability after 15 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	-0.2532950053154578	[1466]	[310,383]	-1	hSpCas9	negative selection	1324697
143941600	143941623	6	-	26627737	RPE1	viability after 18 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-1.3470617404097056	[596]	[72,52]	-7	hSpCas9	negative selection	1407008
143942114	143942137	6	+	26627737	RPE1	viability after 18 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	-0.17150978749152165	[667]	[161,157]	-1	hSpCas9	negative selection	1407009
143942326	143942349	6	+	26627737	RPE1	viability after 18 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	2.3172189745628797	[87]	[84,153]	9	hSpCas9	negative selection	1407010
143942485	143942508	6	-	26627737	RPE1	viability after 18 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	3.3102383292670283	[34]	[40,149]	9	hSpCas9	negative selection	1407011
143948040	143948063	6	+	26627737	RPE1	viability after 18 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	-0.6339344786737904	[1466]	[214,297]	-4	hSpCas9	negative selection	1407012
143941600	143941623	6	-	26627737	HeLa	viability after 8 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-0.4476961708856808	[449]	[179,133,125]	-4	hSpCas9	negative selection	1489323
143942114	143942137	6	+	26627737	HeLa	viability after 8 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	1.12991030848343	[183]	[286,187,81]	8	hSpCas9	negative selection	1489324
143942326	143942349	6	+	26627737	HeLa	viability after 8 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.34610934551021666	[143]	[162,39,55]	3	hSpCas9	negative selection	1489325
143942485	143942508	6	-	26627737	HeLa	viability after 8 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	-0.998926207247449	[259]	[180,0,17]	-7	hSpCas9	negative selection	1489326
143948040	143948063	6	+	26627737	HeLa	viability after 8 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.3642294240967978	[461]	[371,344,95]	3	hSpCas9	negative selection	1489327
143941600	143941623	6	-	26627737	HeLa	viability after 12 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-0.621184345217934	[449]	[158,156,43]	-5	hSpCas9	negative selection	1571638
143942114	143942137	6	+	26627737	HeLa	viability after 12 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	0.32616814260654936	[183]	[69,59,158]	3	hSpCas9	negative selection	1571639
143942326	143942349	6	+	26627737	HeLa	viability after 12 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.2371748829357816	[143]	[85,87,34]	2	hSpCas9	negative selection	1571640
143942485	143942508	6	-	26627737	HeLa	viability after 12 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.19670904410567974	[259]	[136,64,173]	1	hSpCas9	negative selection	1571641
143948040	143948063	6	+	26627737	HeLa	viability after 12 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.21419523549704558	[461]	[223,235,202]	2	hSpCas9	negative selection	1571642
143941600	143941623	6	-	26627737	HeLa	viability after 15 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-1.038332713132287	[449]	[73,101,91]	-7	hSpCas9	negative selection	1653953
143942114	143942137	6	+	26627737	HeLa	viability after 15 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	1.2220636506577411	[183]	[142,274,100]	8	hSpCas9	negative selection	1653954
143942326	143942349	6	+	26627737	HeLa	viability after 15 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.6168806540959966	[143]	[150,26,90]	5	hSpCas9	negative selection	1653955
143942485	143942508	6	-	26627737	HeLa	viability after 15 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.34370256512396186	[259]	[247,0,153]	3	hSpCas9	negative selection	1653956
143948040	143948063	6	+	26627737	HeLa	viability after 15 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	-0.0017730401384913053	[461]	[112,281,167]	0	hSpCas9	negative selection	1653957
143941600	143941623	6	-	26627737	HeLa	viability after 18 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-1.1031149845870927	[449]	[43,81,91]	-7	hSpCas9	negative selection	1736268
143942114	143942137	6	+	26627737	HeLa	viability after 18 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	1.2019153473685122	[183]	[90,227,100]	8	hSpCas9	negative selection	1736269
143942326	143942349	6	+	26627737	HeLa	viability after 18 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.6052718649632132	[143]	[100,20,90]	5	hSpCas9	negative selection	1736270
143942485	143942508	6	-	26627737	HeLa	viability after 18 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.4123758140242406	[259]	[178,0,153]	3	hSpCas9	negative selection	1736271
143948040	143948063	6	+	26627737	HeLa	viability after 18 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.023192215176180836	[461]	[76,239,167]	0	hSpCas9	negative selection	1736272
143941600	143941623	6	-	26627737	HCT116	viability after 6 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	1.2236524106029953	[499]	[102,227]	6	hSpCas9	negative selection	1818583
143942114	143942137	6	+	26627737	HCT116	viability after 6 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	1.3452546001106531	[577]	[226,232]	7	hSpCas9	negative selection	1818584
143942326	143942349	6	+	26627737	HCT116	viability after 6 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.013468599788934665	[399]	[2,94]	0	hSpCas9	negative selection	1818585
143942485	143942508	6	-	26627737	HCT116	viability after 6 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	-0.3521442147071854	[148]	[47,1]	-2	hSpCas9	negative selection	1818586
143948040	143948063	6	+	26627737	HCT116	viability after 6 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	-1.171932530486432	[1269]	[154,51]	-6	hSpCas9	negative selection	1818587
143941600	143941623	6	-	26627737	HCT116	viability after 8 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	0.6999863263114522	[128]	[99,118,126]	6	hSpCas9	negative selection	1900898
143942114	143942137	6	+	26627737	HCT116	viability after 8 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	0.28327283538478976	[203]	[123,135,149]	3	hSpCas9	negative selection	1900899
143942326	143942349	6	+	26627737	HCT116	viability after 8 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.014301449229117358	[150]	[87,55,102]	0	hSpCas9	negative selection	1900900
143942485	143942508	6	-	26627737	HCT116	viability after 8 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	-0.35785965975864936	[228]	[107,124,62]	-4	hSpCas9	negative selection	1900901
143948040	143948063	6	+	26627737	HCT116	viability after 8 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.14436053664580184	[446]	[321,257,237]	1	hSpCas9	negative selection	1900902
143941600	143941623	6	-	26627737	HCT116	viability after 9 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	0.18173593829262205	[499]	[194,116]	1	hSpCas9	negative selection	1983213
143942114	143942137	6	+	26627737	HCT116	viability after 9 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	0.13470708615570504	[577]	[231,119]	1	hSpCas9	negative selection	1983214
143942326	143942349	6	+	26627737	HCT116	viability after 9 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.32886393648192713	[399]	[36,122]	-2	hSpCas9	negative selection	1983215
143942485	143942508	6	-	26627737	HCT116	viability after 9 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.16665696801152752	[148]	[66,26]	1	hSpCas9	negative selection	1983216
143948040	143948063	6	+	26627737	HCT116	viability after 9 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	-0.28883412667898967	[1269]	[333,232]	-2	hSpCas9	negative selection	1983217
143941600	143941623	6	-	26627737	HCT116	viability after 12 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	1.2360502538102964	[128]	[188,56,227]	8	hSpCas9	negative selection	2065528
143942114	143942137	6	+	26627737	HCT116	viability after 12 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	0.05796566300300843	[203]	[99,159,76]	0	hSpCas9	negative selection	2065529
143942326	143942349	6	+	26627737	HCT116	viability after 12 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.04037037246046771	[150]	[77,75,90]	0	hSpCas9	negative selection	2065530
143942485	143942508	6	-	26627737	HCT116	viability after 12 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	-0.027472757171230267	[228]	[166,120,61]	0	hSpCas9	negative selection	2065531
143948040	143948063	6	+	26627737	HCT116	viability after 12 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.044167266214563794	[446]	[281,194,244]	0	hSpCas9	negative selection	2065532
143941600	143941623	6	-	26627737	HCT116	viability after 15 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	-0.4287209949108308	[128]	[60,62,41]	-4	hSpCas9	negative selection	2147843
143942114	143942137	6	+	26627737	HCT116	viability after 15 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	-0.29737033054541173	[203]	[54,122,102]	-3	hSpCas9	negative selection	2147844
143942326	143942349	6	+	26627737	HCT116	viability after 15 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-1.4887874872702807	[150]	[31,43,16]	-8	hSpCas9	negative selection	2147845
143942485	143942508	6	-	26627737	HCT116	viability after 15 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.14434424271376775	[228]	[169,201,67]	1	hSpCas9	negative selection	2147846
143948040	143948063	6	+	26627737	HCT116	viability after 15 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.21620020621993485	[446]	[403,162,339]	2	hSpCas9	negative selection	2147847
143941600	143941623	6	-	26627737	HCT116	viability after 18 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	0.5386471358688402	[128]	[154,27,92]	4	hSpCas9	negative selection	2230158
143942114	143942137	6	+	26627737	HCT116	viability after 18 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	-0.13531846143238246	[203]	[80,70,119]	-1	hSpCas9	negative selection	2230159
143942326	143942349	6	+	26627737	HCT116	viability after 18 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.4599920317468362	[150]	[82,83,136]	4	hSpCas9	negative selection	2230160
143942485	143942508	6	-	26627737	HCT116	viability after 18 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	-0.04360206560986879	[228]	[155,80,85]	0	hSpCas9	negative selection	2230161
143948040	143948063	6	+	26627737	HCT116	viability after 18 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.18935986265329574	[446]	[221,189,334]	1	hSpCas9	negative selection	2230162
143942426	143942449	6	-	24336569	HL60	viability	GGGTCTGTGCCCTGGAGCTAGGG	PLAGL1	ENSG00000118495	0.2424803398569706	[285]	[715]	2	hSpCas9	negative selection	2284483
143942462	143942485	6	-	24336569	HL60	viability	CCCTCCATGCGGCCAGCAGTGGG	PLAGL1	ENSG00000118495	-0.4249152275232939	[936]	[1476]	-4	hSpCas9	negative selection	2284484
143942467	143942490	6	+	24336569	HL60	viability	TGCTGGCCGCATGGAGGGCCAGG	PLAGL1	ENSG00000118495	-0.2255402783023175	[483]	[875]	-2	hSpCas9	negative selection	2284485
143942473	143942496	6	-	24336569	HL60	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	-0.4479214194626784	[583]	[905]	-4	hSpCas9	negative selection	2284486
143942485	143942508	6	-	24336569	HL60	viability	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	-1.2876462947840852	[412]	[357]	-8	hSpCas9	negative selection	2284487
143942492	143942515	6	-	24336569	HL60	viability	ACACCATGCTGGGCTATAAGAGG	PLAGL1	ENSG00000118495	0.21797012478167477	[1072]	[2640]	2	hSpCas9	negative selection	2284488
143942502	143942525	6	-	24336569	HL60	viability	AAGAAGTACAACACCATGCTGGG	PLAGL1	ENSG00000118495	-0.38909330177599344	[1392]	[2250]	-3	hSpCas9	negative selection	2284489
143942597	143942620	6	-	24336569	HL60	viability	ACTGTGAGAAGACGTTCAACCGG	PLAGL1	ENSG00000118495	-0.876435298230668	[405]	[467]	-7	hSpCas9	negative selection	2284490
143942608	143942631	6	+	24336569	HL60	viability	TCTTCTCACAGTGAGCACACTGG	PLAGL1	ENSG00000118495	0.5604432632992502	[562]	[1756]	5	hSpCas9	negative selection	2284491
143942620	143942643	6	+	24336569	HL60	viability	GAGCACACTGGTGAGATTTCTGG	PLAGL1	ENSG00000118495	0.09388457276843842	[471]	[1065]	0	hSpCas9	negative selection	2284492
143942426	143942449	6	-	24336569	KBM7	viability	GGGTCTGTGCCCTGGAGCTAGGG	PLAGL1	ENSG00000118495	1.1276022833796884	[147]	[881]	8	hSpCas9	negative selection	2351660
143942462	143942485	6	-	24336569	KBM7	viability	CCCTCCATGCGGCCAGCAGTGGG	PLAGL1	ENSG00000118495	1.6725294696026993	[310]	[2703]	9	hSpCas9	negative selection	2351661
143942467	143942490	6	+	24336569	KBM7	viability	TGCTGGCCGCATGGAGGGCCAGG	PLAGL1	ENSG00000118495	0.3815362442475324	[328]	[1168]	3	hSpCas9	negative selection	2351662
143942473	143942496	6	-	24336569	KBM7	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	-0.14313852839036123	[331]	[819]	-1	hSpCas9	negative selection	2351663
143942485	143942508	6	-	24336569	KBM7	viability	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	-0.7272835834912907	[382]	[630]	-5	hSpCas9	negative selection	2351664
143942492	143942515	6	-	24336569	KBM7	viability	ACACCATGCTGGGCTATAAGAGG	PLAGL1	ENSG00000118495	0.22129740777515416	[845]	[2689]	2	hSpCas9	negative selection	2351665
143942502	143942525	6	-	24336569	KBM7	viability	AAGAAGTACAACACCATGCTGGG	PLAGL1	ENSG00000118495	0.23740629238442978	[1183]	[3806]	2	hSpCas9	negative selection	2351666
143942597	143942620	6	-	24336569	KBM7	viability	ACTGTGAGAAGACGTTCAACCGG	PLAGL1	ENSG00000118495	0.14167066257537164	[111]	[336]	1	hSpCas9	negative selection	2351667
143942608	143942631	6	+	24336569	KBM7	viability	TCTTCTCACAGTGAGCACACTGG	PLAGL1	ENSG00000118495	0.18633837895751804	[704]	[2187]	1	hSpCas9	negative selection	2351668
143942620	143942643	6	+	24336569	KBM7	viability	GAGCACACTGGTGAGATTTCTGG	PLAGL1	ENSG00000118495	0.2129343371794503	[402]	[1273]	2	hSpCas9	negative selection	2351669
144008527	144008550	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCCACACGTCCTGCGGGCCGG	PLAGL1	ENSG00000118495	0.923147766582594	[795,937]	[478,236]	4	dCas9-VP64	positive selection	2393954
144008546	144008569	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTTTGCCCCCACCGGTGACCCGG	PLAGL1	ENSG00000118495	0.17055565987074406	[2163,2671]	[600,599]	0	dCas9-VP64	positive selection	2393955
144008569	144008592	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCTGTACCTGGGCGACCTTGG	PLAGL1	ENSG00000118495	0.3356324710415022	[835,818]	[191,270]	1	dCas9-VP64	positive selection	2393956
144008522	144008545	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCGGCACCCACACGTCCTGCGG	PLAGL1	ENSG00000118495	-0.6381704573230231	[486,283]	[50,57]	-3	dCas9-VP64	positive selection	2426020
144008527	144008550	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCCACACGTCCTGCGGGCCGG	PLAGL1	ENSG00000118495	4.565177001170699	[596,592]	[128,8804]	9	dCas9-VP64	positive selection	2489209
144008546	144008569	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTTTGCCCCCACCGGTGACCCGG	PLAGL1	ENSG00000118495	0.5014210504054506	[1124,1308]	[330,778]	4	dCas9-VP64	positive selection	2489210
144008569	144008592	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCTGTACCTGGGCGACCTTGG	PLAGL1	ENSG00000118495	1.6702812024344054	[913,831]	[1564,295]	8	dCas9-VP64	positive selection	2489211
144008522	144008545	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCGGCACCCACACGTCCTGCGG	PLAGL1	ENSG00000118495	-0.4853689752163839	[1056,557]	[272,110]	-5	dCas9-VP64	positive selection	2521275
143942416	143942439	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGGAGCTAGGGAGCACCGAGG	PLAGL1	ENSG00000118495	0.1732872490224073	[2,2]	[2,3]	3	hSpCas9	positive selection	3011744
143942400	143942423	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.18448986942532838	[3,4]	[2,4]	4	hSpCas9	positive selection	3011745
143942386	143942409	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACCACCTCAAAGCCCATGCGG	PLAGL1	ENSG00000118495	0.0957130184214154	[3,3]	[4,2]	2	hSpCas9	positive selection	3011746
143942318	143942341	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTAGAAGCATCTTTCACAGTGG	PLAGL1	ENSG00000118495	-0.0642807235933752	[3,3]	[1,3]	-1	hSpCas9	positive selection	3011747
143942416	143942439	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGGAGCTAGGGAGCACCGAGG	PLAGL1	ENSG00000118495	-0.42037723750546013	[2,2]	[0,1]	-6	hSpCas9	positive selection	3079602
143942400	143942423	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.2015963596436264	[3,3]	[2,3]	3	hSpCas9	positive selection	3079603
143942386	143942409	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACCACCTCAAAGCCCATGCGG	PLAGL1	ENSG00000118495	0.66740620591447	[3,3]	[4,3]	9	hSpCas9	positive selection	3079604
143942318	143942341	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTAGAAGCATCTTTCACAGTGG	PLAGL1	ENSG00000118495	-0.23576972557000928	[3,3]	[1,1]	-3	hSpCas9	positive selection	3079605
143942359	143942382		-	24336571	A375	resistance to PLX after 7 days	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.07220380457456355	[6,5]	[7,5]	2	hSpCas9	positive selection	3136017
143948097	143948120		+	24336571	A375	resistance to PLX after 7 days	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.21600043874854258	[10,9]	[9,7]	-6	hSpCas9	positive selection	3136018
143942293	143942316		+	24336571	A375	resistance to PLX after 7 days	GGTGGCGTCGCACATCCTTCCGG	PLAGL1	ENSG00000118495	0.019047551194903534	[67,66]	[73,62]	0	hSpCas9	positive selection	3136019
143942359	143942382		-	24336571	A375	resistance to PLX after 14 days	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.03251432020844325	[5,7]	[2,2]	0	hSpCas9	positive selection	3193810
143948097	143948120		+	24336571	A375	resistance to PLX after 14 days	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.008678695694828265	[15,14]	[5,6]	0	hSpCas9	positive selection	3193811
143942293	143942316		+	24336571	A375	resistance to PLX after 14 days	GGTGGCGTCGCACATCCTTCCGG	PLAGL1	ENSG00000118495	2.554734079437124	[71,56]	[157,197]	9	hSpCas9	positive selection	3193812
143942359	143942382		-	24336571	A375	viability after 7 days	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.1125309105246648	[7]	[6,5]	-2	hSpCas9	negative selection	3251603
143948097	143948120		+	24336571	A375	viability after 7 days	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.3644429792731041	[7]	[10,9]	5	hSpCas9	negative selection	3251604
143942293	143942316		+	24336571	A375	viability after 7 days	GGTGGCGTCGCACATCCTTCCGG	PLAGL1	ENSG00000118495	0.5442723176934148	[48]	[67,66]	7	hSpCas9	negative selection	3251605
143942359	143942382		-	24336571	A375	viability after 14 days	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.03777246656294475	[7]	[5,7]	0	hSpCas9	negative selection	3309396
143948097	143948120		+	24336571	A375	viability after 14 days	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.935260494920584	[7]	[15,14]	9	hSpCas9	negative selection	3309397
143942293	143942316		+	24336571	A375	viability after 14 days	GGTGGCGTCGCACATCCTTCCGG	PLAGL1	ENSG00000118495	0.49027827716050676	[48]	[71,56]	6	hSpCas9	negative selection	3309398
143948070	143948093	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.7654731151161606	[89,89]	[0,0]	4	hSpCas9	positive selection	3386168
143942371	143942394	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.30312990105895976	[123,123]	[0,0]	1	hSpCas9	positive selection	3386169
143942548	143942571	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	-0.7026757206222457	[248,248]	[0,0]	-5	hSpCas9	positive selection	3386170
143942416	143942439	6	-	26780180	HT29	viability (Avana library 4 designs)	CCTGGAGCTAGGGAGCACCGAGG	PLAGL1	ENSG00000118495	1.84100930946337	[]	[]	7	hSpCas9	negative selection	3449835
143942399	143942422	6	+	26780180	HT29	viability (Avana library 4 designs)	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	1.25754446407096	[]	[]	5	hSpCas9	negative selection	3449836
143942386	143942409	6	-	26780180	HT29	viability (Avana library 4 designs)	GGACCACCTCAAAGCCCATGCGG	PLAGL1	ENSG00000118495	0.507241924499907	[]	[]	2	hSpCas9	negative selection	3449837
143942317	143942340	6	+	26780180	HT29	viability (Avana library 4 designs)	TGTAGAAGCATCTTTCACAGTGG	PLAGL1	ENSG00000118495	0.820084331255835	[]	[]	3	hSpCas9	negative selection	3449838
143942416	143942439	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGAGCTAGGGAGCACCGAGG	PLAGL1	ENSG00000118495	4.74326161398098	[]	[]	7	hSpCas9	negative selection	3544788
143942317	143942340	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTAGAAGCATCTTTCACAGTGG	PLAGL1	ENSG00000118495	-2.2124208346354	[]	[]	-3	hSpCas9	negative selection	3544789
143942386	143942409	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACCACCTCAAAGCCCATGCGG	PLAGL1	ENSG00000118495	4.79183750588462	[]	[]	7	hSpCas9	negative selection	3544790
143942399	143942422	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	-0.221499004003735	[]	[]	0	hSpCas9	negative selection	3544791
143942492	143942515	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACACCATGCTGGGCTATAAGAGG	PLAGL1	ENSG00000118495	2.9349806660731	[]	[]	4	hSpCas9	negative selection	3544792
143942068	143942091	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGGGCAGAAGCTCCTAAAGGG	PLAGL1	ENSG00000118495	4.24151684032431	[]	[]	7	hSpCas9	negative selection	3544793
143942416	143942439	6	-	26780180	A375	viability (Avana lentiGuide)	CCTGGAGCTAGGGAGCACCGAGG	PLAGL1	ENSG00000118495	0.200222037238459	[]	[]	0	hSpCas9	negative selection	3653447
143942317	143942340	6	+	26780180	A375	viability (Avana lentiGuide)	TGTAGAAGCATCTTTCACAGTGG	PLAGL1	ENSG00000118495	-3.67775203469981	[]	[]	-6	hSpCas9	negative selection	3653448
143942386	143942409	6	-	26780180	A375	viability (Avana lentiGuide)	GGACCACCTCAAAGCCCATGCGG	PLAGL1	ENSG00000118495	-1.03559906995746	[]	[]	-2	hSpCas9	negative selection	3653449
143942399	143942422	6	+	26780180	A375	viability (Avana lentiGuide)	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	6.00174725349047	[]	[]	5	hSpCas9	negative selection	3653450
143942492	143942515	6	-	26780180	A375	viability (Avana lentiGuide)	ACACCATGCTGGGCTATAAGAGG	PLAGL1	ENSG00000118495	-2.59537281395657	[]	[]	-4	hSpCas9	negative selection	3653451
143942068	143942091	6	+	26780180	A375	viability (Avana lentiGuide)	TCTGGGCAGAAGCTCCTAAAGGG	PLAGL1	ENSG00000118495	-1.34210769767007	[]	[]	-2	hSpCas9	negative selection	3653452
143942416	143942439	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGAGCTAGGGAGCACCGAGG	PLAGL1	ENSG00000118495	0.2648218864929553	[4]	[5,4]	7	hSpCas9	positive selection	3762106
143942317	143942340	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTAGAAGCATCTTTCACAGTGG	PLAGL1	ENSG00000118495	-0.2226120563042832	[5]	[4,4]	-4	hSpCas9	positive selection	3762107
143942386	143942409	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACCACCTCAAAGCCCATGCGG	PLAGL1	ENSG00000118495	0.2606068182807471	[4]	[5,3]	7	hSpCas9	positive selection	3762108
143942399	143942422	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.11537365762203186	[5]	[5,5]	3	hSpCas9	positive selection	3762109
143942492	143942515	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACCATGCTGGGCTATAAGAGG	PLAGL1	ENSG00000118495	0.20448640037066904	[6]	[7,6]	5	hSpCas9	positive selection	3762110
143942068	143942091	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGGGCAGAAGCTCCTAAAGGG	PLAGL1	ENSG00000118495	-0.09464339720775358	[4]	[4,3]	-1	hSpCas9	positive selection	3762111
143942416	143942439	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGAGCTAGGGAGCACCGAGG	PLAGL1	ENSG00000118495	0.09159038316764971	[5]	[3,4]	2	hSpCas9	positive selection	3870713
143942317	143942340	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTAGAAGCATCTTTCACAGTGG	PLAGL1	ENSG00000118495	0.1850397001946763	[4]	[5,3]	4	hSpCas9	positive selection	3870714
143942386	143942409	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACCACCTCAAAGCCCATGCGG	PLAGL1	ENSG00000118495	0.05276496882357409	[4]	[5,2]	1	hSpCas9	positive selection	3870715
143942399	143942422	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.16635016114489215	[6]	[5,5]	4	hSpCas9	positive selection	3870716
143942492	143942515	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACCATGCTGGGCTATAAGAGG	PLAGL1	ENSG00000118495	0.33984164727409244	[6]	[6,7]	8	hSpCas9	positive selection	3870717
143942068	143942091	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGGGCAGAAGCTCCTAAAGGG	PLAGL1	ENSG00000118495	0.3879897446411456	[4]	[4,5]	9	hSpCas9	positive selection	3870718
143942050	143942073	6	+	26780180	A375	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	1.00308339663154	[]	[]	4	hSpCas9	negative selection	3981532
143942359	143942382	6	-	26780180	A375	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.645452530519461	[]	[]	2	hSpCas9	negative selection	3981533
143942548	143942571	6	-	26780180	A375	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.915207036772404	[]	[]	4	hSpCas9	negative selection	3981534
143948097	143948120	6	+	26780180	A375	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	1.21594887664526	[]	[]	6	hSpCas9	negative selection	3981535
143942371	143942394	6	+	26780180	A375	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	1.0283284124742	[]	[]	5	hSpCas9	negative selection	3981536
143948070	143948093	6	+	26780180	A375	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	1.50495010250541	[]	[]	8	hSpCas9	negative selection	3981537
143942050	143942073	6	+	26780180	HT29	viability (GeCKOv2 library)	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	1.53372312007301	[]	[]	7	hSpCas9	negative selection	4089498
143942359	143942382	6	-	26780180	HT29	viability (GeCKOv2 library)	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.614706248823796	[]	[]	2	hSpCas9	negative selection	4089499
143942548	143942571	6	-	26780180	HT29	viability (GeCKOv2 library)	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	1.51995526799138	[]	[]	7	hSpCas9	negative selection	4089500
143948097	143948120	6	+	26780180	HT29	viability (GeCKOv2 library)	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	1.46193261131984	[]	[]	7	hSpCas9	negative selection	4089501
143942371	143942394	6	+	26780180	HT29	viability (GeCKOv2 library)	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.802109358451374	[]	[]	3	hSpCas9	negative selection	4089502
143948070	143948093	6	+	26780180	HT29	viability (GeCKOv2 library)	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	1.3900696282085	[]	[]	7	hSpCas9	negative selection	4089503
143942359	143942382	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.15421864064385285	[3]	[1,1]	-4	hSpCas9	positive selection	4161009
143948097	143948120	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.7035387492423001	[2]	[2,2]	9	hSpCas9	positive selection	4161010
143942293	143942316	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTGGCGTCGCACATCCTTCCGG	PLAGL1	ENSG00000118495	0.6963460620137389	[5]	[6,7]	9	hSpCas9	positive selection	4161011
143942359	143942382	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.40494671066192295	[2]	[0,0,0,1]	3	hSpCas9	positive selection	4225031
143948097	143948120	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.5379198153560394	[2]	[4,2,0,0]	3	hSpCas9	positive selection	4225032
143942293	143942316	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTGGCGTCGCACATCCTTCCGG	PLAGL1	ENSG00000118495	1.0571932923513914	[5]	[5,5,6,4]	7	hSpCas9	positive selection	4225033
143948097	143948120	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.219305531862584	[3]	[3,0]	-4	hSpCas9	positive selection	4290603
143942050	143942073	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.5150770436924952	[3]	[2,4]	9	hSpCas9	positive selection	4290604
143942359	143942382	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.09006289661316746	[1]	[1,0]	1	hSpCas9	positive selection	4290605
143948070	143948093	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.03612056234206573	[2]	[2,1]	0	hSpCas9	positive selection	4354855
143942371	143942394	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	-0.3378421895636793	[2]	[2,0]	-6	hSpCas9	positive selection	4354856
143942548	143942571	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.3869017460704774	[2]	[2,3]	7	hSpCas9	positive selection	4354857
143942201	143942223	6	+	27760321	OCIAML3	viability	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	0.12618284982955175	[896,756]	[655,764]	1	hSpCas9	negative selection	4428323
143942290	143942312	6	-	27760321	OCIAML3	viability	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	0.2468505902301253	[413,421]	[428,337]	3	hSpCas9	negative selection	4428324
143942308	143942330	6	-	27760321	OCIAML3	viability	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.40095220064642684	[612,505]	[519,646]	5	hSpCas9	negative selection	4428325
143942327	143942349	6	+	27760321	OCIAML3	viability	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.3116948397875138	[613,651]	[309,519]	-3	hSpCas9	negative selection	4428326
143942356	143942378	6	+	27760321	OCIAML3	viability	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	0.3344131069057343	[553,532]	[446,653]	4	hSpCas9	negative selection	4428327
143942201	143942223	6	+	27760321	OCIAML2	viability	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	0.3097672790703224	[896,756]	[691,1002]	4	hSpCas9	negative selection	4511786
143942290	143942312	6	-	27760321	OCIAML2	viability	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	0.8791892887641506	[413,421]	[447,856]	9	hSpCas9	negative selection	4511787
143942308	143942330	6	-	27760321	OCIAML2	viability	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.07944286256123895	[612,505]	[384,595]	1	hSpCas9	negative selection	4511788
143942327	143942349	6	+	27760321	OCIAML2	viability	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.11749890002146357	[613,651]	[450,505]	-1	hSpCas9	negative selection	4511789
143942356	143942378	6	+	27760321	OCIAML2	viability	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	0.49503543565787983	[553,532]	[517,755]	6	hSpCas9	negative selection	4511790
143942201	143942223	6	+	27760321	MV411	viability	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	4.270704160647121e-05	[896,756]	[247,987]	0	hSpCas9	negative selection	4595249
143942290	143942312	6	-	27760321	MV411	viability	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	1.7733549234046333	[413,421]	[929,971]	9	hSpCas9	negative selection	4595250
143942308	143942330	6	-	27760321	MV411	viability	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	-0.002162946954148981	[612,505]	[340,405]	0	hSpCas9	negative selection	4595251
143942327	143942349	6	+	27760321	MV411	viability	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.7700187125509417	[613,651]	[199,315]	-5	hSpCas9	negative selection	4595252
143942356	143942378	6	+	27760321	MV411	viability	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	-0.16059154721423793	[553,532]	[344,285]	-1	hSpCas9	negative selection	4595253
143942201	143942223	6	+	27760321	HL60	viability	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	0.301346130529179	[896,756]	[760,901]	4	hSpCas9	negative selection	4678712
143942290	143942312	6	-	27760321	HL60	viability	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	0.4999704485645055	[413,421]	[545,419]	6	hSpCas9	negative selection	4678713
143942308	143942330	6	-	27760321	HL60	viability	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.694469358305907	[612,505]	[727,744]	7	hSpCas9	negative selection	4678714
143942327	143942349	6	+	27760321	HL60	viability	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.4311287907002581	[613,651]	[425,342]	-5	hSpCas9	negative selection	4678715
143942356	143942378	6	+	27760321	HL60	viability	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	0.5436983345659543	[553,532]	[640,655]	6	hSpCas9	negative selection	4678716
143942201	143942223	6	+	27760321	HT1080	viability	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	0.93255756081293	[756,590]	[722,281]	5	hSpCas9	negative selection	4762175
143942290	143942312	6	-	27760321	HT1080	viability	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	-1.502254247564195	[421,329]	[81,20]	-5	hSpCas9	negative selection	4762176
143942308	143942330	6	-	27760321	HT1080	viability	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.4790027894325202	[505,394]	[231,269]	2	hSpCas9	negative selection	4762177
143942327	143942349	6	+	27760321	HT1080	viability	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.46205057824468876	[651,508]	[382,247]	2	hSpCas9	negative selection	4762178
143942356	143942378	6	+	27760321	HT1080	viability	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	-1.3766939374994522	[532,415]	[78,65]	-5	hSpCas9	negative selection	4762179
143942201	143942223	6	+	27760321	HT29	viability after 7 days	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	-0.2598845748459703	[756,590]	[841,588,754]	-4	hSpCas9	negative selection	4845638
143942290	143942312	6	-	27760321	HT29	viability after 7 days	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	0.014879234988070741	[421,329]	[475,402,580]	0	hSpCas9	negative selection	4845639
143942308	143942330	6	-	27760321	HT29	viability after 7 days	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.32641440112553904	[505,394]	[561,917,675]	5	hSpCas9	negative selection	4845640
143942327	143942349	6	+	27760321	HT29	viability after 7 days	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.46363994861506336	[651,508]	[697,492,456]	-6	hSpCas9	negative selection	4845641
143942356	143942378	6	+	27760321	HT29	viability after 7 days	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	-0.4211315066477073	[532,415]	[488,458,423]	-6	hSpCas9	negative selection	4845642
143942201	143942223	6	+	27760321	HT29	viability after 25 days	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	0.23374188844969224	[756,590]	[852,677,1220]	2	hSpCas9	negative selection	4929101
143942290	143942312	6	-	27760321	HT29	viability after 25 days	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	-0.0890043276809385	[421,329]	[308,413,504]	-1	hSpCas9	negative selection	4929102
143942308	143942330	6	-	27760321	HT29	viability after 25 days	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.24393481604329098	[505,394]	[493,838,489]	2	hSpCas9	negative selection	4929103
143942327	143942349	6	+	27760321	HT29	viability after 25 days	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.5724946257832184	[651,508]	[314,523,513]	-5	hSpCas9	negative selection	4929104
143942356	143942378	6	+	27760321	HT29	viability after 25 days	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	0.11825636027627329	[532,415]	[440,547,807]	1	hSpCas9	negative selection	4929105
143942201	143942223	6	+	27760321	HT29	viability after 22 days	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	0.15502331622989396	[756,590]	[649,839,1120]	1	hSpCas9	negative selection	5012564
143942290	143942312	6	-	27760321	HT29	viability after 22 days	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	0.019083915141992064	[421,329]	[349,321,653]	0	hSpCas9	negative selection	5012565
143942308	143942330	6	-	27760321	HT29	viability after 22 days	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.3346267555827314	[505,394]	[476,749,748]	3	hSpCas9	negative selection	5012566
143942327	143942349	6	+	27760321	HT29	viability after 22 days	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.16316587028370133	[651,508]	[464,904,429]	-2	hSpCas9	negative selection	5012567
143942356	143942378	6	+	27760321	HT29	viability after 22 days	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	-0.09908517600031524	[532,415]	[751,255,521]	-1	hSpCas9	negative selection	5012568
143942201	143942223	6	+	27760321	HT29	viability after 19 days	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	-0.3113591735271649	[756,590]	[633,620,609]	-3	hSpCas9	negative selection	5096027
143942290	143942312	6	-	27760321	HT29	viability after 19 days	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	0.6209488580854845	[421,329]	[413,617,915]	6	hSpCas9	negative selection	5096028
143942308	143942330	6	-	27760321	HT29	viability after 19 days	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.2862611850897609	[505,394]	[554,804,520]	2	hSpCas9	negative selection	5096029
143942327	143942349	6	+	27760321	HT29	viability after 19 days	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.1376252663889328	[651,508]	[506,628,1019]	1	hSpCas9	negative selection	5096030
143942356	143942378	6	+	27760321	HT29	viability after 19 days	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	-0.018016613225822264	[532,415]	[562,449,594]	0	hSpCas9	negative selection	5096031
143942201	143942223	6	+	27760321	HT29	viability after 16 days	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	0.1954238827496253	[756,590]	[1051,675,884]	2	hSpCas9	negative selection	5179490
143942290	143942312	6	-	27760321	HT29	viability after 16 days	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	-0.0006522082479052949	[421,329]	[316,563,366]	0	hSpCas9	negative selection	5179491
143942308	143942330	6	-	27760321	HT29	viability after 16 days	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.46360382788984716	[505,394]	[760,589,742]	5	hSpCas9	negative selection	5179492
143942327	143942349	6	+	27760321	HT29	viability after 16 days	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.1379662056085097	[651,508]	[583,706,475]	-1	hSpCas9	negative selection	5179493
143942356	143942378	6	+	27760321	HT29	viability after 16 days	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	-0.07825744246207678	[532,415]	[550,387,576]	-1	hSpCas9	negative selection	5179494
143942201	143942223	6	+	27760321	HT29	viability after 13 days	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	0.2026486036552524	[756,590]	[826,792,1068]	2	hSpCas9	negative selection	5262953
143942290	143942312	6	-	27760321	HT29	viability after 13 days	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	0.5094557140905969	[421,329]	[720,474,663]	6	hSpCas9	negative selection	5262954
143942308	143942330	6	-	27760321	HT29	viability after 13 days	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.6080067546699282	[505,394]	[682,912,793]	7	hSpCas9	negative selection	5262955
143942327	143942349	6	+	27760321	HT29	viability after 13 days	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.316614503052376	[651,508]	[511,650,463]	-4	hSpCas9	negative selection	5262956
143942356	143942378	6	+	27760321	HT29	viability after 13 days	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	-0.07188426409185378	[532,415]	[696,321,549]	-1	hSpCas9	negative selection	5262957
143942201	143942223	6	+	27760321	HT29	viability after 10 days	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	0.02951618282878654	[756,590]	[903,664,998]	0	hSpCas9	negative selection	5346416
143942290	143942312	6	-	27760321	HT29	viability after 10 days	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	0.014847717727946547	[421,329]	[318,442,655]	0	hSpCas9	negative selection	5346417
143942308	143942330	6	-	27760321	HT29	viability after 10 days	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.3910766370470243	[505,394]	[819,765,629]	5	hSpCas9	negative selection	5346418
143942327	143942349	6	+	27760321	HT29	viability after 10 days	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.5255174009100688	[651,508]	[596,511,403]	-6	hSpCas9	negative selection	5346419
143942356	143942378	6	+	27760321	HT29	viability after 10 days	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	-0.12328780072589934	[532,415]	[524,438,661]	-2	hSpCas9	negative selection	5346420
143942201	143942223	6	+	27760321	MOLM13	viability	CTTCTTGGTATGCCGGGTGAGG	PLAGL1	ENSG00000118495	-0.37190420767422505	[896,756]	[355,361]	-2	hSpCas9	negative selection	5429879
143942290	143942312	6	-	27760321	MOLM13	viability	AAGGATGTGCGACGCCACCTGG	PLAGL1	ENSG00000118495	0.6089096600336239	[413,421]	[513,230]	4	hSpCas9	negative selection	5429880
143942308	143942330	6	-	27760321	MOLM13	viability	AGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.5783052454706665	[612,505]	[170,722]	4	hSpCas9	negative selection	5429881
143942327	143942349	6	+	27760321	MOLM13	viability	TCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-1.404629867140188	[613,651]	[166,108]	-7	hSpCas9	negative selection	5429882
143942356	143942378	6	+	27760321	MOLM13	viability	TTTCCTTGGTTCCGCTAGGGGG	PLAGL1	ENSG00000118495	0.7092199170829043	[553,532]	[492,509]	5	hSpCas9	negative selection	5429883
144007859	144007882	6	+	27661255	K562	viability	GCGGCGTCCAGGGGGTCCGGCGG	PLAGL1	ENSG00000118495	0.001490164242273495	[692,598]	[579,464]	0	dCas9-KRAB	negative selection	5502329
144008146	144008169	6	+	27661255	K562	viability	GCGGCCATGACGGCGACCCGGGG	PLAGL1	ENSG00000118495	-0.0539164983386497	[1089,832]	[784,707]	-2	dCas9-KRAB	negative selection	5502330
144064114	144064137	6	+	27661255	K562	viability	GCGGGGCGGGCGCTAGGTGGCGG	PLAGL1	ENSG00000118495	-0.1996734647602172	[119,99]	[79,73]	-6	dCas9-KRAB	negative selection	5502331
144064191	144064214	6	+	27661255	K562	viability	GCTGCAGACGACGGAGAAAAGGG	PLAGL1	ENSG00000118495	0.14306245187084676	[860,967]	[852,763]	5	dCas9-KRAB	negative selection	5502332
144064566	144064589	6	+	27661255	K562	viability	GCGGCGCAGCTCCGACTCGGCGG	PLAGL1	ENSG00000118495	0.21962984001857078	[401,361]	[389,326]	7	dCas9-KRAB	negative selection	5502333
144064579	144064602	6	+	27661255	K562	viability	GACTCGGCGGCGCGGAAAAGGGG	PLAGL1	ENSG00000118495	0.009078322770885716	[564,575]	[553,376]	0	dCas9-KRAB	negative selection	5502334
144008225	144008248	6	-	27661255	K562	viability	GCGGGTGCTGGACGGACGGACGG	PLAGL1	ENSG00000118495	-0.015782725406613296	[848,763]	[679,602]	0	dCas9-KRAB	negative selection	5502335
144064512	144064535	6	-	27661255	K562	viability	GAGCTGACCCAGTGGGCCACGGG	PLAGL1	ENSG00000118495	-0.006132967330352512	[1269,1354]	[1106,987]	0	dCas9-KRAB	negative selection	5502336
144064555	144064578	6	-	27661255	K562	viability	GAGCTGCGCCGCACGCCCAGCGG	PLAGL1	ENSG00000118495	-0.05860708720479246	[1132,1147]	[927,828]	-2	dCas9-KRAB	negative selection	5502337
143948097	143948120	6	+	27260156	BXPC3	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.28325745173147554	[627]	[584,472,536,560]	-6	hSpCas9	negative selection	5563063
143942050	143942073	6	+	27260156	BXPC3	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	-0.16335818597695298	[504]	[345,514,491,550]	-4	hSpCas9	negative selection	5563064
143942359	143942382	6	-	27260156	BXPC3	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.07058332699532799	[132]	[140,118,83,190]	-2	hSpCas9	negative selection	5563065
143948070	143948093	6	+	27260156	BXPC3	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.13871999230354604	[293]	[254,258,289,319]	-3	hSpCas9	negative selection	5627315
143942371	143942394	6	+	27260156	BXPC3	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	-0.05851287217582618	[346]	[320,385,299,388]	-1	hSpCas9	negative selection	5627316
143942548	143942571	6	-	27260156	BXPC3	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.21311500572422712	[412]	[394,543,551,519]	5	hSpCas9	negative selection	5627317
143948097	143948120	6	+	27260156	A673	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.06584014615669431	[627]	[819,647,657,770]	-2	hSpCas9	negative selection	5684314
143942050	143942073	6	+	27260156	A673	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	-0.041485885322477205	[504]	[663,595,495,609]	-1	hSpCas9	negative selection	5684315
143942359	143942382	6	-	27260156	A673	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.014454458652554791	[132]	[148,156,138,200]	0	hSpCas9	negative selection	5684316
143948070	143948093	6	+	27260156	A673	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.17161597587383437	[293]	[382,214,341,323]	-4	hSpCas9	negative selection	5748566
143942371	143942394	6	+	27260156	A673	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.3192628227555221	[346]	[617,368,513,596]	7	hSpCas9	negative selection	5748567
143942548	143942571	6	-	27260156	A673	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.30684993017545903	[412]	[643,569,658,581]	7	hSpCas9	negative selection	5748568
143948097	143948120	6	+	27260156	A375	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.164594433621155	[627]	[688,883,592,499]	-2	hSpCas9	negative selection	5805565
143942050	143942073	6	+	27260156	A375	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.30032054600206887	[504]	[821,825,763,528]	4	hSpCas9	negative selection	5805566
143942359	143942382	6	-	27260156	A375	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.2417818936487519	[132]	[119,108,264,38]	-3	hSpCas9	negative selection	5805567
143948070	143948093	6	+	27260156	A375	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.03229881078252317	[293]	[240,585,259,293]	0	hSpCas9	negative selection	5869817
143942371	143942394	6	+	27260156	A375	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.23725636623654744	[346]	[361,669,443,460]	3	hSpCas9	negative selection	5869818
143942548	143942571	6	-	27260156	A375	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.6269103073323318	[412]	[911,750,821,520]	8	hSpCas9	negative selection	5869819
143948097	143948120	6	+	27260156	COLO741	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.1812586668410196	[627]	[1065,745,926]	4	hSpCas9	negative selection	5926816
143942050	143942073	6	+	27260156	COLO741	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.11520123564952416	[504]	[665,652,767]	2	hSpCas9	negative selection	5926817
143942359	143942382	6	-	27260156	COLO741	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.35896705550298136	[132]	[198,237,214]	7	hSpCas9	negative selection	5926818
143948070	143948093	6	+	27260156	COLO741	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.32913823225636174	[293]	[400,276,231]	-6	hSpCas9	negative selection	5991068
143942371	143942394	6	+	27260156	COLO741	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.022360575203335953	[346]	[473,443,434]	0	hSpCas9	negative selection	5991069
143942548	143942571	6	-	27260156	COLO741	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.18917722399954487	[412]	[496,669,625]	4	hSpCas9	negative selection	5991070
143948097	143948120	6	+	27260156	CAL120	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.08391945861121075	[627]	[869,422,934]	-1	hSpCas9	negative selection	6048067
143942050	143942073	6	+	27260156	CAL120	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.526553557414137	[504]	[923,546,1240]	7	hSpCas9	negative selection	6048068
143942359	143942382	6	-	27260156	CAL120	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.0654559859668653	[132]	[128,180,159]	-1	hSpCas9	negative selection	6048069
143948070	143948093	6	+	27260156	CAL120	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.01749773564598922	[293]	[634,166,348]	0	hSpCas9	negative selection	6112319
143942371	143942394	6	+	27260156	CAL120	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.8856866304952087	[346]	[1329,781,368]	9	hSpCas9	negative selection	6112320
143942548	143942571	6	-	27260156	CAL120	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.11355997818212561	[412]	[517,581,561]	1	hSpCas9	negative selection	6112321
143948097	143948120	6	+	27260156	CADOES1	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.05689503521936429	[627]	[482,887,610,442]	1	hSpCas9	negative selection	6169318
143942050	143942073	6	+	27260156	CADOES1	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.05289661177235251	[504]	[659,470,315,501]	0	hSpCas9	negative selection	6169319
143942359	143942382	6	-	27260156	CADOES1	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.1419383121885296	[132]	[157,99,171,114]	2	hSpCas9	negative selection	6169320
143948070	143948093	6	+	27260156	CADOES1	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.11571571999904706	[293]	[270,300,269,344]	2	hSpCas9	negative selection	6233570
143942371	143942394	6	+	27260156	CADOES1	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.16005045231442555	[346]	[526,315,260,336]	2	hSpCas9	negative selection	6233571
143942548	143942571	6	-	27260156	CADOES1	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.3862858440716869	[412]	[460,633,349,565]	6	hSpCas9	negative selection	6233572
143948097	143948120	6	+	27260156	EWS502	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.06201879017391376	[627]	[763,574,575,615]	-1	hSpCas9	negative selection	6290569
143942050	143942073	6	+	27260156	EWS502	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.1774943085768474	[504]	[646,565,589,610]	3	hSpCas9	negative selection	6290570
143942359	143942382	6	-	27260156	EWS502	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.37417369635899345	[132]	[64,167,143,56]	-6	hSpCas9	negative selection	6290571
143948070	143948093	6	+	27260156	EWS502	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.14423138192426488	[293]	[216,206,336,383]	-3	hSpCas9	negative selection	6354821
143942371	143942394	6	+	27260156	EWS502	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.12755127274541	[346]	[456,254,522,367]	2	hSpCas9	negative selection	6354822
143942548	143942571	6	-	27260156	EWS502	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.33629224126123125	[412]	[610,472,570,547]	6	hSpCas9	negative selection	6354823
143948097	143948120	6	+	27260156	EW8	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.2250907364067226	[627]	[577,468,283,450]	-4	hSpCas9	negative selection	6411820
143942050	143942073	6	+	27260156	EW8	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.0754544104163825	[504]	[434,326,492,457]	1	hSpCas9	negative selection	6411821
143942359	143942382	6	-	27260156	EW8	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.5208081051004081	[132]	[51,93,115,28]	-7	hSpCas9	negative selection	6411822
143948070	143948093	6	+	27260156	EW8	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.19117701845037127	[293]	[172,198,202,255]	-4	hSpCas9	negative selection	6476072
143942371	143942394	6	+	27260156	EW8	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.39677714013511217	[346]	[304,343,413,401]	7	hSpCas9	negative selection	6476073
143942548	143942571	6	-	27260156	EW8	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.15162536203673596	[412]	[489,341,330,342]	3	hSpCas9	negative selection	6476074
143948097	143948120	6	+	27260156	CORL105	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.12401756906258049	[627]	[743,739,874,855]	2	hSpCas9	negative selection	6533071
143942050	143942073	6	+	27260156	CORL105	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.387568932536144	[504]	[930,693,675,783]	7	hSpCas9	negative selection	6533072
143942359	143942382	6	-	27260156	CORL105	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.02157082334135163	[132]	[98,250,103,147]	0	hSpCas9	negative selection	6533073
143948070	143948093	6	+	27260156	CORL105	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.04755985213784708	[293]	[382,261,297,472]	0	hSpCas9	negative selection	6597323
143942371	143942394	6	+	27260156	CORL105	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.1139644467906833	[346]	[495,409,464,393]	2	hSpCas9	negative selection	6597324
143942548	143942571	6	-	27260156	CORL105	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.2729484412975723	[412]	[650,465,696,544]	5	hSpCas9	negative selection	6597325
143948097	143948120	6	+	27260156	HS294T	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.98340045117487	[627]	[376,718,421,386]	9	hSpCas9	negative selection	6654322
143942050	143942073	6	+	27260156	HS294T	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.29242529871405776	[504]	[174,179,259,370]	4	hSpCas9	negative selection	6654323
143942359	143942382	6	-	27260156	HS294T	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.1973718909386133	[132]	[38,95,53,44]	2	hSpCas9	negative selection	6654324
143948070	143948093	6	+	27260156	HS294T	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.0585296142529087	[293]	[109,143,130,81]	0	hSpCas9	negative selection	6718574
143942371	143942394	6	+	27260156	HS294T	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.10456342403513946	[346]	[137,146,122,173]	1	hSpCas9	negative selection	6718575
143942548	143942571	6	-	27260156	HS294T	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.024859704631115143	[412]	[128,166,200,153]	0	hSpCas9	negative selection	6718576
143948097	143948120	6	+	27260156	HCC44	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.22165894338835337	[627]	[746,426,676,629]	-4	hSpCas9	negative selection	6775573
143942050	143942073	6	+	27260156	HCC44	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.44858167100971175	[504]	[869,526,928,852]	7	hSpCas9	negative selection	6775574
143942359	143942382	6	-	27260156	HCC44	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.1817338665242223	[132]	[39,219,119,269]	3	hSpCas9	negative selection	6775575
143948070	143948093	6	+	27260156	HCC44	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.1764852693888429	[293]	[282,211,349,347]	-3	hSpCas9	negative selection	6839825
143942371	143942394	6	+	27260156	HCC44	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.04869220244629241	[346]	[295,397,440,479]	0	hSpCas9	negative selection	6839826
143942548	143942571	6	-	27260156	HCC44	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.4384155313129996	[412]	[757,521,1060,297]	7	hSpCas9	negative selection	6839827
143948097	143948120	6	+	27260156	G402	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.23594256648404993	[627]	[806,892,1054,839]	3	hSpCas9	negative selection	6896824
143942050	143942073	6	+	27260156	G402	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.06152704397992566	[504]	[521,708,574,744]	0	hSpCas9	negative selection	6896825
143942359	143942382	6	-	27260156	G402	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.5755600500606981	[132]	[317,140,342,172]	7	hSpCas9	negative selection	6896826
143948070	143948093	6	+	27260156	G402	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.24730162084541318	[293]	[512,199,390,588]	3	hSpCas9	negative selection	6961076
143942371	143942394	6	+	27260156	G402	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	-0.014842956188445777	[346]	[505,635,332,233]	0	hSpCas9	negative selection	6961077
143942548	143942571	6	-	27260156	G402	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.5618848245357655	[412]	[722,816,922,521]	7	hSpCas9	negative selection	6961078
143948097	143948120	6	+	27260156	L33	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.2014092119954074	[627]	[463,263,324,560]	-4	hSpCas9	negative selection	7018075
143942050	143942073	6	+	27260156	L33	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.20704714089766002	[504]	[532,274,391,505]	4	hSpCas9	negative selection	7018076
143942359	143942382	6	-	27260156	L33	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.6683141440724532	[132]	[176,96,130,223]	9	hSpCas9	negative selection	7018077
143948070	143948093	6	+	27260156	L33	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.021310449761785644	[293]	[283,115,204,265]	0	hSpCas9	negative selection	7082327
143942371	143942394	6	+	27260156	L33	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	-0.04587655723547346	[346]	[311,132,195,395]	-1	hSpCas9	negative selection	7082328
143942548	143942571	6	-	27260156	L33	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.22401997001951737	[412]	[372,219,384,410]	5	hSpCas9	negative selection	7082329
143948097	143948120	6	+	27260156	K562	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.10402443952360169	[627]	[827,783,391,436]	1	hSpCas9	negative selection	7139326
143942050	143942073	6	+	27260156	K562	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	-0.2924839872062626	[504]	[343,533,374,231]	-4	hSpCas9	negative selection	7139327
143942359	143942382	6	-	27260156	K562	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-1.3491018801044543	[132]	[22,47,81,31]	-8	hSpCas9	negative selection	7139328
143948070	143948093	6	+	27260156	K562	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.3043663117199675	[293]	[219,194,418,425]	4	hSpCas9	negative selection	7203578
143942371	143942394	6	+	27260156	K562	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.4469171108488313	[346]	[430,419,386,437]	5	hSpCas9	negative selection	7203579
143942548	143942571	6	-	27260156	K562	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	-0.18323698921640874	[412]	[387,473,277,179]	-2	hSpCas9	negative selection	7203580
143948097	143948120	6	+	27260156	HT29	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.03255722843772857	[627]	[768,788,766,669]	0	hSpCas9	negative selection	7260577
143942050	143942073	6	+	27260156	HT29	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.09964508114980293	[504]	[639,465,884,621]	2	hSpCas9	negative selection	7260578
143942359	143942382	6	-	27260156	HT29	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.4354681073725155	[132]	[100,62,177,127]	-7	hSpCas9	negative selection	7260579
143948070	143948093	6	+	27260156	HT29	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.102350955748848	[293]	[523,435,300,296]	2	hSpCas9	negative selection	7324829
143942371	143942394	6	+	27260156	HT29	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.251176277172047	[346]	[604,370,458,558]	5	hSpCas9	negative selection	7324830
143942548	143942571	6	-	27260156	HT29	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.19425363463177744	[412]	[653,598,566,491]	4	hSpCas9	negative selection	7324831
143948097	143948120	6	+	27260156	MHHES1	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.05352677683457113	[627]	[780,922,770,519]	1	hSpCas9	negative selection	7381828
143942050	143942073	6	+	27260156	MHHES1	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.1316896107202683	[504]	[737,621,664,496]	2	hSpCas9	negative selection	7381829
143942359	143942382	6	-	27260156	MHHES1	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.009559017537100312	[132]	[152,95,137,189]	0	hSpCas9	negative selection	7381830
143948070	143948093	6	+	27260156	MHHES1	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.4378417601722241	[293]	[219,466,167,156]	-7	hSpCas9	negative selection	7446080
143942371	143942394	6	+	27260156	MHHES1	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.28040399523627596	[346]	[446,619,547,320]	5	hSpCas9	negative selection	7446081
143942548	143942571	6	-	27260156	MHHES1	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.4757567823128993	[412]	[642,1002,551,454]	8	hSpCas9	negative selection	7446082
143948097	143948120	6	+	27260156	MEWO	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.00983636917894376	[627]	[624,485,647]	0	hSpCas9	negative selection	7503079
143942050	143942073	6	+	27260156	MEWO	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	-0.22911918666833192	[504]	[533,303,396]	-5	hSpCas9	negative selection	7503080
143942359	143942382	6	-	27260156	MEWO	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.3498521086869748	[132]	[113,108,72]	-6	hSpCas9	negative selection	7503081
143948070	143948093	6	+	27260156	MEWO	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.08926813095575115	[293]	[254,239,279]	-2	hSpCas9	negative selection	7567331
143942371	143942394	6	+	27260156	MEWO	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	-0.17268264372238523	[346]	[379,248,252]	-4	hSpCas9	negative selection	7567332
143942548	143942571	6	-	27260156	MEWO	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.13947318844734985	[412]	[551,468,279]	3	hSpCas9	negative selection	7567333
143948097	143948120	6	+	27260156	LNCAPCLONEFGC	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.008929426520905503	[627]	[458,547,623,641]	0	hSpCas9	negative selection	7624330
143942050	143942073	6	+	27260156	LNCAPCLONEFGC	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.059819333224243446	[504]	[417,486,547,464]	0	hSpCas9	negative selection	7624331
143942359	143942382	6	-	27260156	LNCAPCLONEFGC	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.22065053849018668	[132]	[116,87,184,181]	3	hSpCas9	negative selection	7624332
143948070	143948093	6	+	27260156	LNCAPCLONEFGC	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.13236998297582103	[293]	[163,208,252,350]	-2	hSpCas9	negative selection	7688582
143942371	143942394	6	+	27260156	LNCAPCLONEFGC	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.4739846146383859	[346]	[350,510,410,465]	7	hSpCas9	negative selection	7688583
143942548	143942571	6	-	27260156	LNCAPCLONEFGC	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.26589462643166584	[412]	[533,464,453,343]	4	hSpCas9	negative selection	7688584
143948097	143948120	6	+	27260156	PANC0327	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.01841759447090463	[627]	[978,259,697,338]	0	hSpCas9	negative selection	7745581
143942050	143942073	6	+	27260156	PANC0327	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	-0.12627581817826863	[504]	[275,679,325,315]	-2	hSpCas9	negative selection	7745582
143942359	143942382	6	-	27260156	PANC0327	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.7291492918264595	[132]	[22,56,108,93]	-7	hSpCas9	negative selection	7745583
143948070	143948093	6	+	27260156	PANC0327	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.10355657369534588	[293]	[287,388,277,153]	1	hSpCas9	negative selection	7809833
143942371	143942394	6	+	27260156	PANC0327	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.11663119390540239	[346]	[172,310,609,232]	1	hSpCas9	negative selection	7809834
143942548	143942571	6	-	27260156	PANC0327	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.460938684802925	[412]	[524,604,265,611]	6	hSpCas9	negative selection	7809835
143948097	143948120	6	+	27260156	NCIH2009	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.1797220952763599	[627]	[1199,801,1021]	2	hSpCas9	negative selection	7866832
143942050	143942073	6	+	27260156	NCIH2009	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.13393056611942766	[504]	[840,635,859]	1	hSpCas9	negative selection	7866833
143942359	143942382	6	-	27260156	NCIH2009	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.20592168974612202	[132]	[147,240,89]	-3	hSpCas9	negative selection	7866834
143948070	143948093	6	+	27260156	NCIH2009	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.1974102443300748	[293]	[491,489,433]	2	hSpCas9	negative selection	7931084
143942371	143942394	6	+	27260156	NCIH2009	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.3921667318035678	[346]	[816,492,635]	5	hSpCas9	negative selection	7931085
143942548	143942571	6	-	27260156	NCIH2009	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.758599187272676	[412]	[1037,990,909]	9	hSpCas9	negative selection	7931086
143948097	143948120	6	+	27260156	NCIH1373	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.0016870327683400355	[627]	[671,728,499,240]	0	hSpCas9	negative selection	7988083
143942050	143942073	6	+	27260156	NCIH1373	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.47824241998898037	[504]	[700,519,728,326]	5	hSpCas9	negative selection	7988084
143942359	143942382	6	-	27260156	NCIH1373	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.5586539163459201	[132]	[79,135,71,28]	-5	hSpCas9	negative selection	7988085
143948070	143948093	6	+	27260156	NCIH1373	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.7743257158469178	[293]	[311,121,164,51]	-7	hSpCas9	negative selection	8052335
143942371	143942394	6	+	27260156	NCIH1373	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.4784476236630543	[346]	[666,273,587,181]	5	hSpCas9	negative selection	8052336
143942548	143942571	6	-	27260156	NCIH1373	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.23291968301507515	[412]	[967,441,633,47]	2	hSpCas9	negative selection	8052337
143948097	143948120	6	+	27260156	PATU8902	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.09680022712732428	[627]	[1014,832,641,817]	-1	hSpCas9	negative selection	8109334
143942050	143942073	6	+	27260156	PATU8902	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.11150611117280364	[504]	[1109,549,451,1027]	1	hSpCas9	negative selection	8109335
143942359	143942382	6	-	27260156	PATU8902	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.20384797238155516	[132]	[54,286,318,158]	2	hSpCas9	negative selection	8109336
143948070	143948093	6	+	27260156	PATU8902	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.14076511825388272	[293]	[628,281,198,795]	1	hSpCas9	negative selection	8173586
143942371	143942394	6	+	27260156	PATU8902	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.2116382618529836	[346]	[721,328,425,819]	2	hSpCas9	negative selection	8173587
143942548	143942571	6	-	27260156	PATU8902	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.25539183269493004	[412]	[506,505,463,1409]	2	hSpCas9	negative selection	8173588
143948097	143948120	6	+	27260156	PANC1	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.37294968337151185	[627]	[656,882,646,642]	6	hSpCas9	negative selection	8230585
143942050	143942073	6	+	27260156	PANC1	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	-0.30380312014544175	[504]	[322,591,417,150]	-5	hSpCas9	negative selection	8230586
143942359	143942382	6	-	27260156	PANC1	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.17686711394147947	[132]	[132,224,116,68]	3	hSpCas9	negative selection	8230587
143948070	143948093	6	+	27260156	PANC1	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.4268223168157991	[293]	[211,168,156,202]	-6	hSpCas9	negative selection	8294837
143942371	143942394	6	+	27260156	PANC1	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.14059002774958207	[346]	[411,465,249,223]	2	hSpCas9	negative selection	8294838
143942548	143942571	6	-	27260156	PANC1	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.36768841978324074	[412]	[493,601,411,359]	6	hSpCas9	negative selection	8294839
143948097	143948120	6	+	27260156	PANC0813	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.2758356447430304	[627]	[987,489,602,401]	-4	hSpCas9	negative selection	8351836
143942050	143942073	6	+	27260156	PANC0813	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.12191515105253899	[504]	[725,545,712,605]	2	hSpCas9	negative selection	8351837
143942359	143942382	6	-	27260156	PANC0813	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.5697827198392058	[132]	[333,145,213,241]	8	hSpCas9	negative selection	8351838
143948070	143948093	6	+	27260156	PANC0813	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.1778428823327463	[293]	[367,490,319,380]	3	hSpCas9	negative selection	8416088
143942371	143942394	6	+	27260156	PANC0813	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.0027902493228264547	[346]	[384,565,442,245]	0	hSpCas9	negative selection	8416089
143942548	143942571	6	-	27260156	PANC0813	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.3172350456293873	[412]	[668,532,567,649]	5	hSpCas9	negative selection	8416090
143948097	143948120	6	+	27260156	RDES	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.3159432438927803	[627]	[554,471,712,582]	-5	hSpCas9	negative selection	8473087
143942050	143942073	6	+	27260156	RDES	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.11624516628936492	[504]	[455,510,718,909]	2	hSpCas9	negative selection	8473088
143942359	143942382	6	-	27260156	RDES	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.20111151135591632	[132]	[98,161,137,133]	-3	hSpCas9	negative selection	8473089
143948070	143948093	6	+	27260156	RDES	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.03259723005925785	[293]	[356,305,315,400]	0	hSpCas9	negative selection	8537339
143942371	143942394	6	+	27260156	RDES	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.16557067824012645	[346]	[311,338,663,522]	2	hSpCas9	negative selection	8537340
143942548	143942571	6	-	27260156	RDES	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.3670584085894427	[412]	[502,460,887,631]	6	hSpCas9	negative selection	8537341
143948097	143948120	6	+	27260156	PC3	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.11019542922631459	[627]	[439,829,1251,418]	2	hSpCas9	negative selection	8594338
143942050	143942073	6	+	27260156	PC3	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.04888893776321594	[504]	[381,465,759,575]	1	hSpCas9	negative selection	8594339
143942359	143942382	6	-	27260156	PC3	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.49022284401471605	[132]	[59,87,185,84]	-8	hSpCas9	negative selection	8594340
143948070	143948093	6	+	27260156	PC3	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.2305674813412092	[293]	[122,215,337,400]	-5	hSpCas9	negative selection	8658590
143942371	143942394	6	+	27260156	PC3	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	-0.034314477340620875	[346]	[162,360,456,470]	0	hSpCas9	negative selection	8658591
143942548	143942571	6	-	27260156	PC3	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	-0.2806388621781279	[412]	[225,415,548,251]	-6	hSpCas9	negative selection	8658592
143948097	143948120	6	+	27260156	PATU8988T	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.06935045655378919	[627]	[491,362,874,800]	1	hSpCas9	negative selection	8715589
143942050	143942073	6	+	27260156	PATU8988T	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	-0.4467394909740992	[504]	[379,474,248,338]	-6	hSpCas9	negative selection	8715590
143942359	143942382	6	-	27260156	PATU8988T	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.892117201243552	[132]	[236,277,313,117]	9	hSpCas9	negative selection	8715591
143948070	143948093	6	+	27260156	PATU8988T	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.186755604769969	[293]	[303,546,335,109]	3	hSpCas9	negative selection	8779841
143942371	143942394	6	+	27260156	PATU8988T	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.5984751358846433	[346]	[335,832,393,498]	8	hSpCas9	negative selection	8779842
143942548	143942571	6	-	27260156	PATU8988T	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.191626860947188	[412]	[288,415,425,708]	3	hSpCas9	negative selection	8779843
143948097	143948120	6	+	27260156	T47D	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.2090487519512233	[627]	[750,580,540,665]	-4	hSpCas9	negative selection	8836840
143942050	143942073	6	+	27260156	T47D	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.1467666594355344	[504]	[676,528,759,647]	3	hSpCas9	negative selection	8836841
143942359	143942382	6	-	27260156	T47D	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.12334462332115903	[132]	[220,127,179,148]	2	hSpCas9	negative selection	8836842
143948070	143948093	6	+	27260156	T47D	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.03385367477511614	[293]	[369,240,326,410]	0	hSpCas9	negative selection	8901092
143942371	143942394	6	+	27260156	T47D	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.29059910609145456	[346]	[444,449,545,540]	6	hSpCas9	negative selection	8901093
143942548	143942571	6	-	27260156	T47D	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.17649897948284643	[412]	[520,547,562,541]	4	hSpCas9	negative selection	8901094
143948097	143948120	6	+	27260156	SU8686	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	0.12829217028996925	[627]	[595,604,744,813]	2	hSpCas9	negative selection	8958091
143942050	143942073	6	+	27260156	SU8686	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.3993294190727131	[504]	[591,675,675,705]	6	hSpCas9	negative selection	8958092
143942359	143942382	6	-	27260156	SU8686	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	0.15362880708849214	[132]	[137,87,132,251]	2	hSpCas9	negative selection	8958093
143948070	143948093	6	+	27260156	SU8686	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.1880361432017148	[293]	[188,188,228,463]	-3	hSpCas9	negative selection	9022343
143942371	143942394	6	+	27260156	SU8686	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.38940985034575076	[346]	[389,427,558,431]	6	hSpCas9	negative selection	9022344
143942548	143942571	6	-	27260156	SU8686	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.4402900529694393	[412]	[498,521,566,657]	7	hSpCas9	negative selection	9022345
143948097	143948120	6	+	27260156	SKES1	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.3847170930241935	[627]	[545,540,466,387]	-7	hSpCas9	negative selection	9079342
143942050	143942073	6	+	27260156	SKES1	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	-0.02239434254200552	[504]	[524,698,373,419]	0	hSpCas9	negative selection	9079343
143942359	143942382	6	-	27260156	SKES1	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.2560156274513261	[132]	[126,73,89,145]	-5	hSpCas9	negative selection	9079344
143948070	143948093	6	+	27260156	SKES1	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.37167430352375386	[293]	[324,193,202,195]	-7	hSpCas9	negative selection	9143594
143942371	143942394	6	+	27260156	SKES1	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.24198244173332104	[346]	[295,445,459,417]	5	hSpCas9	negative selection	9143595
143942548	143942571	6	-	27260156	SKES1	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.46833904318886427	[412]	[655,551,615,470]	8	hSpCas9	negative selection	9143596
143948097	143948120	6	+	27260156	TOV112D	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.20339516599473115	[627]	[653,676,550,348]	-4	hSpCas9	negative selection	9200593
143942050	143942073	6	+	27260156	TOV112D	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.2137572959469468	[504]	[672,555,419,692]	4	hSpCas9	negative selection	9200594
143942359	143942382	6	-	27260156	TOV112D	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.6070265095460621	[132]	[100,125,70,62]	-8	hSpCas9	negative selection	9200595
143948070	143948093	6	+	27260156	TOV112D	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.27592020318682386	[293]	[362,279,230,120]	-5	hSpCas9	negative selection	9264845
143942371	143942394	6	+	27260156	TOV112D	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.1290721710715132	[346]	[387,287,490,331]	2	hSpCas9	negative selection	9264846
143942548	143942571	6	-	27260156	TOV112D	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.2524866679393711	[412]	[618,611,243,533]	5	hSpCas9	negative selection	9264847
143948097	143948120	6	+	27260156	TC71	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.13435352015009305	[627]	[660,536,592,664]	-4	hSpCas9	negative selection	9321844
143942050	143942073	6	+	27260156	TC71	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	-0.19760768082172542	[504]	[444,461,443,542]	-5	hSpCas9	negative selection	9321845
143942359	143942382	6	-	27260156	TC71	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.028844806294525682	[132]	[113,136,183,121]	0	hSpCas9	negative selection	9321846
143948070	143948093	6	+	27260156	TC71	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	0.044888488782615754	[293]	[272,285,400,339]	1	hSpCas9	negative selection	9386096
143942371	143942394	6	+	27260156	TC71	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.449514568257416	[346]	[530,485,518,493]	9	hSpCas9	negative selection	9386097
143942548	143942571	6	-	27260156	TC71	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.04537939317989109	[412]	[364,458,371,647]	1	hSpCas9	negative selection	9386098
143948097	143948120	6	+	27260156	TC32	viability	GGAACGTCTTGCCACATAACTGG	PLAGL1	ENSG00000118495	-0.1813477876324836	[627]	[489,280,744,679]	-3	hSpCas9	negative selection	9443095
143942050	143942073	6	+	27260156	TC32	viability	AGCTACTTGCAAGCCCGTTCTGG	PLAGL1	ENSG00000118495	0.2691075198651672	[504]	[438,462,789,662]	5	hSpCas9	negative selection	9443096
143942359	143942382	6	-	27260156	TC32	viability	GAAGCCCCCTAGCGGAACCAAGG	PLAGL1	ENSG00000118495	-0.2976922944868954	[132]	[93,103,109,92]	-5	hSpCas9	negative selection	9443097
143948070	143948093	6	+	27260156	TC32	viability	TGTGAATCGTGAACTTCTCCAGG	PLAGL1	ENSG00000118495	-0.18878117164299213	[293]	[282,98,363,282]	-3	hSpCas9	negative selection	9507347
143942371	143942394	6	+	27260156	TC32	viability	TAGGGGGCTTCTCTTCCGCATGG	PLAGL1	ENSG00000118495	0.3419533524071606	[346]	[396,344,528,403]	6	hSpCas9	negative selection	9507348
143942548	143942571	6	-	27260156	TC32	viability	GACCCACGACCCCAACAAAATGG	PLAGL1	ENSG00000118495	0.4235001498015157	[412]	[479,367,760,548]	7	hSpCas9	negative selection	9507349
143941600	143941623	6	-	27869803	HPAFII	viability after 27 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	1.3216001723854642	[153]	[107,280,NaN]	9	hSpCas9	negative selection	9593907
143942114	143942137	6	+	27869803	HPAFII	viability after 27 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	-0.5533522334725159	[168]	[101,25,NaN]	-4	hSpCas9	negative selection	9593908
143942326	143942349	6	+	27869803	HPAFII	viability after 27 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.9491270160260378	[144]	[6,263,NaN]	7	hSpCas9	negative selection	9593909
143942485	143942508	6	-	27869803	HPAFII	viability after 27 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	-0.7362734099803432	[122]	[70,11,NaN]	-5	hSpCas9	negative selection	9593910
143948040	143948063	6	+	27869803	HPAFII	viability after 27 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.42811289831608856	[305]	[240,195,NaN]	3	hSpCas9	negative selection	9593911
143941600	143941623	6	-	27869803	HPAFII	viability after 15 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	0.701506737712659	[153]	[270,267,NaN]	7	hSpCas9	negative selection	9676356
143942114	143942137	6	+	27869803	HPAFII	viability after 15 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	-0.15784672968628177	[168]	[221,125,NaN]	-2	hSpCas9	negative selection	9676357
143942326	143942349	6	+	27869803	HPAFII	viability after 15 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.301410980861132	[144]	[130,229,NaN]	3	hSpCas9	negative selection	9676358
143942485	143942508	6	-	27869803	HPAFII	viability after 15 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.157857686102453	[122]	[255,79,NaN]	1	hSpCas9	negative selection	9676359
143948040	143948063	6	+	27869803	HPAFII	viability after 15 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	-0.4184746550041917	[305]	[213,265,NaN]	-4	hSpCas9	negative selection	9676360
143941600	143941623	6	-	27869803	ASPC1	viability after 36 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	0.4702406164789076	[301]	[223,39,173]	5	hSpCas9	negative selection	9758805
143942114	143942137	6	+	27869803	ASPC1	viability after 36 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	0.5173456995143446	[384]	[91,186,264]	5	hSpCas9	negative selection	9758806
143942326	143942349	6	+	27869803	ASPC1	viability after 36 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.28848087594839233	[236]	[71,69,144]	3	hSpCas9	negative selection	9758807
143942485	143942508	6	-	27869803	ASPC1	viability after 36 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.766573902106051	[248]	[185,72,178]	7	hSpCas9	negative selection	9758808
143948040	143948063	6	+	27869803	ASPC1	viability after 36 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.7001099199107421	[728]	[457,518,293]	7	hSpCas9	negative selection	9758809
143941600	143941623	6	-	27869803	PATU8988S	viability after 35 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	0.6118635618554199	[379]	[184,282,NaN]	6	hSpCas9	negative selection	9841254
143942114	143942137	6	+	27869803	PATU8988S	viability after 35 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	0.3252161195434631	[408]	[151,260,NaN]	4	hSpCas9	negative selection	9841255
143942326	143942349	6	+	27869803	PATU8988S	viability after 35 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	-0.0888437265701667	[217]	[106,57,NaN]	-1	hSpCas9	negative selection	9841256
143942485	143942508	6	-	27869803	PATU8988S	viability after 35 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	-0.09919600387372496	[270]	[54,148,NaN]	-1	hSpCas9	negative selection	9841257
143948040	143948063	6	+	27869803	PATU8988S	viability after 35 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.31026098232047705	[680]	[374,304,NaN]	3	hSpCas9	negative selection	9841258
143941600	143941623	6	-	27869803	PATU8988S	viability after 31 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	0.5582154728259434	[379]	[168,291,NaN]	6	hSpCas9	negative selection	9923703
143942114	143942137	6	+	27869803	PATU8988S	viability after 31 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	0.322630777471132	[408]	[188,222,NaN]	4	hSpCas9	negative selection	9923704
143942326	143942349	6	+	27869803	PATU8988S	viability after 31 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	0.006518596118520348	[217]	[85,88,NaN]	0	hSpCas9	negative selection	9923705
143942485	143942508	6	-	27869803	PATU8988S	viability after 31 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.07910090058695374	[270]	[63,177,NaN]	1	hSpCas9	negative selection	9923706
143948040	143948063	6	+	27869803	PATU8988S	viability after 31 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.40584572739827884	[680]	[357,361,NaN]	5	hSpCas9	negative selection	9923707
143941600	143941623	6	-	27869803	HPAFII	viability after 35 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	1.161061162590506	[153]	[147,203,NaN]	7	hSpCas9	negative selection	10006152
143942114	143942137	6	+	27869803	HPAFII	viability after 35 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	0.19807028481576588	[168]	[155,32,NaN]	1	hSpCas9	negative selection	10006153
143942326	143942349	6	+	27869803	HPAFII	viability after 35 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	2.1512748998767326	[144]	[17,672,NaN]	9	hSpCas9	negative selection	10006154
143942485	143942508	6	-	27869803	HPAFII	viability after 35 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.8565197390265316	[122]	[195,18,NaN]	5	hSpCas9	negative selection	10006155
143948040	143948063	6	+	27869803	HPAFII	viability after 35 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	-0.21304512981203708	[305]	[127,139,NaN]	-1	hSpCas9	negative selection	10006156
143941600	143941623	6	-	27869803	HPAFII	viability after 31 days	TGGGAATAGCACTCTTGCCCTGG	PLAGL1	ENSG00000118495	1.2075525694302547	[153]	[145,257,NaN]	8	hSpCas9	negative selection	10088601
143942114	143942137	6	+	27869803	HPAFII	viability after 31 days	CAGTTGGAATGAAGGCGAGATGG	PLAGL1	ENSG00000118495	-0.6258317766243272	[168]	[82,37,NaN]	-4	hSpCas9	negative selection	10088602
143942326	143942349	6	+	27869803	HPAFII	viability after 31 days	ATCTTTCACAGTGGTCGCACTGG	PLAGL1	ENSG00000118495	1.6143328734564935	[144]	[17,500,NaN]	9	hSpCas9	negative selection	10088603
143942485	143942508	6	-	27869803	HPAFII	viability after 31 days	GCTGGGCTATAAGAGGCACCTGG	PLAGL1	ENSG00000118495	0.3099139650671996	[122]	[142,22,NaN]	2	hSpCas9	negative selection	10088604
143948040	143948063	6	+	27869803	HPAFII	viability after 31 days	TGTACGGCCGCTCCCTGGAGTGG	PLAGL1	ENSG00000118495	0.3001561071240454	[305]	[187,236,NaN]	2	hSpCas9	negative selection	10088605
143941935	143941958	6	+	28162770	P31FUJ	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	0.30062999566669557	[75]	[109]	3	hSpCas9	negative selection	10212318
143942275	143942298	6	+	28162770	P31FUJ	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	-0.05549767260646879	[259]	[293]	0	hSpCas9	negative selection	10212319
143941924	143941947	6	+	28162770	P31FUJ	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-5.014161917939038	[109]	[3]	-9	hSpCas9	negative selection	10212320
143942473	143942496	6	-	28162770	P31FUJ	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	-0.09044928100304778	[269]	[297]	-1	hSpCas9	negative selection	10212321
143942308	143942331	6	-	28162770	P31FUJ	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.6113268847008583	[82]	[148]	7	hSpCas9	negative selection	10212322
143941558	143941581	6	+	28162770	P31FUJ	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.24173630661312706	[379]	[527]	2	hSpCas9	negative selection	10212323
143942503	143942526	6	-	28162770	P31FUJ	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.19090816978423386	[538]	[722]	2	hSpCas9	negative selection	10212324
143942437	143942460	6	+	28162770	P31FUJ	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	0.20816375985499092	[385]	[523]	2	hSpCas9	negative selection	10212325
143942399	143942422	6	+	28162770	P31FUJ	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.1646883132827579	[516]	[680]	1	hSpCas9	negative selection	10212326
143942383	143942406	6	+	28162770	P31FUJ	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	0.6526694075592343	[189]	[350]	7	hSpCas9	negative selection	10212327
143941935	143941958	6	+	28162770	TF1	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10381684
143942275	143942298	6	+	28162770	TF1	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	NaN	[NaN]	[244]	1	hSpCas9	negative selection	10381685
143941924	143941947	6	+	28162770	TF1	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10381686
143942473	143942496	6	-	28162770	TF1	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	NaN	[NaN]	[216]	1	hSpCas9	negative selection	10381687
143942308	143942331	6	-	28162770	TF1	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	NaN	[NaN]	[212]	1	hSpCas9	negative selection	10381688
143941558	143941581	6	+	28162770	TF1	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	NaN	[NaN]	[198]	1	hSpCas9	negative selection	10381689
143942503	143942526	6	-	28162770	TF1	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	NaN	[NaN]	[891]	1	hSpCas9	negative selection	10381690
143942437	143942460	6	+	28162770	TF1	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	NaN	[NaN]	[333]	1	hSpCas9	negative selection	10381691
143942399	143942422	6	+	28162770	TF1	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	NaN	[NaN]	[274]	1	hSpCas9	negative selection	10381692
143942383	143942406	6	+	28162770	TF1	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10381693
143941935	143941958	6	+	28162770	SKM1	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	0.27110770636947623	[14]	[31]	2	hSpCas9	negative selection	10551050
143942275	143942298	6	+	28162770	SKM1	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	1.1178773095404237	[48]	[187]	9	hSpCas9	negative selection	10551051
143941924	143941947	6	+	28162770	SKM1	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-2.217930374353145	[49]	[18]	-8	hSpCas9	negative selection	10551052
143942473	143942496	6	-	28162770	SKM1	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	0.6817647198511698	[66]	[189]	6	hSpCas9	negative selection	10551053
143942308	143942331	6	-	28162770	SKM1	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.15200309344505003	[27]	[54]	1	hSpCas9	negative selection	10551054
143941558	143941581	6	+	28162770	SKM1	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.07943446749440497	[105]	[197]	0	hSpCas9	negative selection	10551055
143942503	143942526	6	-	28162770	SKM1	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.40039072331444236	[125]	[293]	4	hSpCas9	negative selection	10551056
143942437	143942460	6	+	28162770	SKM1	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-0.008656338122018492	[102]	[180]	0	hSpCas9	negative selection	10551057
143942399	143942422	6	+	28162770	SKM1	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.44569408518165143	[102]	[247]	4	hSpCas9	negative selection	10551058
143942383	143942406	6	+	28162770	SKM1	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	-0.7453804164190929	[54]	[57]	-5	hSpCas9	negative selection	10551059
143941935	143941958	6	+	28162770	SKM1	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	0.27110770636947623	[14]	[31]	2	hSpCas9	negative selection	10720416
143942275	143942298	6	+	28162770	SKM1	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	1.1178773095404237	[48]	[187]	9	hSpCas9	negative selection	10720417
143941924	143941947	6	+	28162770	SKM1	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-2.217930374353145	[49]	[18]	-8	hSpCas9	negative selection	10720418
143942473	143942496	6	-	28162770	SKM1	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	0.6817647198511698	[66]	[189]	6	hSpCas9	negative selection	10720419
143942308	143942331	6	-	28162770	SKM1	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.15200309344505003	[27]	[54]	1	hSpCas9	negative selection	10720420
143941558	143941581	6	+	28162770	SKM1	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.07943446749440497	[105]	[197]	0	hSpCas9	negative selection	10720421
143942503	143942526	6	-	28162770	SKM1	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.40039072331444236	[125]	[293]	4	hSpCas9	negative selection	10720422
143942437	143942460	6	+	28162770	SKM1	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-0.008656338122018492	[102]	[180]	0	hSpCas9	negative selection	10720423
143942399	143942422	6	+	28162770	SKM1	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.44569408518165143	[102]	[247]	4	hSpCas9	negative selection	10720424
143942383	143942406	6	+	28162770	SKM1	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	-0.7453804164190929	[54]	[57]	-5	hSpCas9	negative selection	10720425
143941935	143941958	6	+	28162770	PL21	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	0.29324901888080146	[59]	[31]	2	hSpCas9	negative selection	10889782
143942275	143942298	6	+	28162770	PL21	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	-0.39209088669587544	[198]	[65]	-3	hSpCas9	negative selection	10889783
143941924	143941947	6	+	28162770	PL21	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-1.3531140265044979	[134]	[22]	-7	hSpCas9	negative selection	10889784
143942473	143942496	6	-	28162770	PL21	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	0.027560159601029754	[407]	[180]	0	hSpCas9	negative selection	10889785
143942308	143942331	6	-	28162770	PL21	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	-1.2101443548188888	[100]	[18]	-7	hSpCas9	negative selection	10889786
143941558	143941581	6	+	28162770	PL21	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.3831696035549945	[413]	[234]	3	hSpCas9	negative selection	10889787
143942503	143942526	6	-	28162770	PL21	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.5470881239259948	[422]	[268]	5	hSpCas9	negative selection	10889788
143942437	143942460	6	+	28162770	PL21	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	0.1285863534642862	[247]	[117]	1	hSpCas9	negative selection	10889789
143942399	143942422	6	+	28162770	PL21	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.38535448695622765	[291]	[165]	3	hSpCas9	negative selection	10889790
143942383	143942406	6	+	28162770	PL21	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	0.8496423674051868	[101]	[79]	7	hSpCas9	negative selection	10889791
143941935	143941958	6	+	28162770	P31FUJ	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	0.30062999566669557	[75]	[109]	3	hSpCas9	negative selection	11059148
143942275	143942298	6	+	28162770	P31FUJ	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	-0.05549767260646879	[259]	[293]	0	hSpCas9	negative selection	11059149
143941924	143941947	6	+	28162770	P31FUJ	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-5.014161917939038	[109]	[3]	-9	hSpCas9	negative selection	11059150
143942473	143942496	6	-	28162770	P31FUJ	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	-0.09044928100304778	[269]	[297]	-1	hSpCas9	negative selection	11059151
143942308	143942331	6	-	28162770	P31FUJ	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.6113268847008583	[82]	[148]	7	hSpCas9	negative selection	11059152
143941558	143941581	6	+	28162770	P31FUJ	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.24173630661312706	[379]	[527]	2	hSpCas9	negative selection	11059153
143942503	143942526	6	-	28162770	P31FUJ	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.19090816978423386	[538]	[722]	2	hSpCas9	negative selection	11059154
143942437	143942460	6	+	28162770	P31FUJ	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	0.20816375985499092	[385]	[523]	2	hSpCas9	negative selection	11059155
143942399	143942422	6	+	28162770	P31FUJ	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.1646883132827579	[516]	[680]	1	hSpCas9	negative selection	11059156
143942383	143942406	6	+	28162770	P31FUJ	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	0.6526694075592343	[189]	[350]	7	hSpCas9	negative selection	11059157
143941935	143941958	6	+	28162770	OCIAML5	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	0.0020825626725478052	[25]	[46]	0	hSpCas9	negative selection	11228514
143942275	143942298	6	+	28162770	OCIAML5	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	0.455831964119307	[123]	[306]	4	hSpCas9	negative selection	11228515
143941924	143941947	6	+	28162770	OCIAML5	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-3.2255249663914416	[56]	[10]	-9	hSpCas9	negative selection	11228516
143942473	143942496	6	-	28162770	OCIAML5	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	-0.23875944444887903	[167]	[256]	-2	hSpCas9	negative selection	11228517
143942308	143942331	6	-	28162770	OCIAML5	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.5312620686875087	[68]	[179]	4	hSpCas9	negative selection	11228518
143941558	143941581	6	+	28162770	OCIAML5	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	-0.09137678263399507	[192]	[326]	0	hSpCas9	negative selection	11228519
143942503	143942526	6	-	28162770	OCIAML5	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.37871363596517016	[293]	[689]	3	hSpCas9	negative selection	11228520
143942437	143942460	6	+	28162770	OCIAML5	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-0.718978337602056	[237]	[260]	-5	hSpCas9	negative selection	11228521
143942399	143942422	6	+	28162770	OCIAML5	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.18156420701728326	[211]	[433]	1	hSpCas9	negative selection	11228522
143942383	143942406	6	+	28162770	OCIAML5	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	0.906115509211905	[80]	[273]	7	hSpCas9	negative selection	11228523
143941935	143941958	6	+	28162770	EOL1	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	-0.7257061894023407	[112]	[35]	-5	hSpCas9	negative selection	11397880
143942275	143942298	6	+	28162770	EOL1	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	-0.5534995252341098	[311]	[111]	-4	hSpCas9	negative selection	11397881
143941924	143941947	6	+	28162770	EOL1	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-4.736517708236413	[252]	[4]	-9	hSpCas9	negative selection	11397882
143942473	143942496	6	-	28162770	EOL1	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	-0.7742826937089005	[671]	[206]	-5	hSpCas9	negative selection	11397883
143942308	143942331	6	-	28162770	EOL1	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.9310318051407331	[221]	[222]	7	hSpCas9	negative selection	11397884
143941558	143941581	6	+	28162770	EOL1	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	2.4995899333151224	[680]	[2028]	9	hSpCas9	negative selection	11397885
143942503	143942526	6	-	28162770	EOL1	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	-0.5210780475417323	[571]	[209]	-4	hSpCas9	negative selection	11397886
143942437	143942460	6	+	28162770	EOL1	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-0.22818746857426264	[437]	[196]	-2	hSpCas9	negative selection	11397887
143942399	143942422	6	+	28162770	EOL1	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.744913559148294	[409]	[361]	6	hSpCas9	negative selection	11397888
143942383	143942406	6	+	28162770	EOL1	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	0.9811312999369018	[149]	[155]	8	hSpCas9	negative selection	11397889
143941935	143941958	6	+	28162770	MOLM13	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	1.5991339148228312	[41]	[91]	9	hSpCas9	negative selection	11567246
143942275	143942298	6	+	28162770	MOLM13	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	-0.07643113467923143	[279]	[191]	0	hSpCas9	negative selection	11567247
143941924	143941947	6	+	28162770	MOLM13	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-1.7337444796250716	[160]	[34]	-7	hSpCas9	negative selection	11567248
143942473	143942496	6	-	28162770	MOLM13	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	0.1444024588006546	[462]	[369]	1	hSpCas9	negative selection	11567249
143942308	143942331	6	-	28162770	MOLM13	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.7579686103926014	[228]	[279]	6	hSpCas9	negative selection	11567250
143941558	143941581	6	+	28162770	MOLM13	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.6823711865381858	[417]	[484]	5	hSpCas9	negative selection	11567251
143942503	143942526	6	-	28162770	MOLM13	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	-0.6815838622562436	[822]	[370]	-4	hSpCas9	negative selection	11567252
143942437	143942460	6	+	28162770	MOLM13	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-0.8362640116148075	[483]	[195]	-4	hSpCas9	negative selection	11567253
143942399	143942422	6	+	28162770	MOLM13	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	-0.0806497109267037	[527]	[360]	0	hSpCas9	negative selection	11567254
143942383	143942406	6	+	28162770	MOLM13	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	-2.5119327365177906	[212]	[26]	-8	hSpCas9	negative selection	11567255
143941935	143941958	6	+	28162770	HEL	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	-0.70518447141995	[83]	[32]	-4	hSpCas9	negative selection	11736612
143942275	143942298	6	+	28162770	HEL	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	0.5945297389577372	[212]	[205]	5	hSpCas9	negative selection	11736613
143941924	143941947	6	+	28162770	HEL	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-4.942223668720799	[191]	[3]	-9	hSpCas9	negative selection	11736614
143942473	143942496	6	-	28162770	HEL	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	-0.7877414129408111	[406]	[150]	-5	hSpCas9	negative selection	11736615
143942308	143942331	6	-	28162770	HEL	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.3522236897444561	[158]	[129]	3	hSpCas9	negative selection	11736616
143941558	143941581	6	+	28162770	HEL	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	-0.08595914618224865	[405]	[244]	0	hSpCas9	negative selection	11736617
143942503	143942526	6	-	28162770	HEL	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.0038375241683972217	[544]	[349]	0	hSpCas9	negative selection	11736618
143942437	143942460	6	+	28162770	HEL	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-1.6250334928401	[365]	[75]	-7	hSpCas9	negative selection	11736619
143942399	143942422	6	+	28162770	HEL	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.08772955338082855	[428]	[291]	0	hSpCas9	negative selection	11736620
143942383	143942406	6	+	28162770	HEL	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	0.5328612142279834	[149]	[138]	4	hSpCas9	negative selection	11736621
143941935	143941958	6	+	28162770	MV411	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	1.5997392947136564	[46]	[119]	9	hSpCas9	negative selection	11905978
143942275	143942298	6	+	28162770	MV411	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	0.10364776418540927	[252]	[228]	0	hSpCas9	negative selection	11905979
143941924	143941947	6	+	28162770	MV411	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-4.807844884718414	[132]	[3]	-9	hSpCas9	negative selection	11905980
143942473	143942496	6	-	28162770	MV411	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	-0.41240361725277586	[345]	[218]	-3	hSpCas9	negative selection	11905981
143942308	143942331	6	-	28162770	MV411	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	-0.3964186389919493	[149]	[95]	-3	hSpCas9	negative selection	11905982
143941558	143941581	6	+	28162770	MV411	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.5534680187899292	[291]	[360]	5	hSpCas9	negative selection	11905983
143942503	143942526	6	-	28162770	MV411	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.32468054971523586	[399]	[421]	3	hSpCas9	negative selection	11905984
143942437	143942460	6	+	28162770	MV411	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-0.5199016924269497	[319]	[187]	-4	hSpCas9	negative selection	11905985
143942399	143942422	6	+	28162770	MV411	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.4237603234232383	[399]	[451]	4	hSpCas9	negative selection	11905986
143942383	143942406	6	+	28162770	MV411	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	1.3242531478336064	[127]	[269]	9	hSpCas9	negative selection	11905987
143941935	143941958	6	+	28162770	MONOMAC1	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	0.8029631529404462	[37]	[75]	7	hSpCas9	negative selection	12075344
143942275	143942298	6	+	28162770	MONOMAC1	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	-0.08552853184256318	[111]	[120]	0	hSpCas9	negative selection	12075345
143941924	143941947	6	+	28162770	MONOMAC1	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-1.5358387605113122	[85]	[33]	-8	hSpCas9	negative selection	12075346
143942473	143942496	6	-	28162770	MONOMAC1	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	-0.30495218622644116	[221]	[205]	-3	hSpCas9	negative selection	12075347
143942308	143942331	6	-	28162770	MONOMAC1	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.7738168072809299	[74]	[146]	7	hSpCas9	negative selection	12075348
143941558	143941581	6	+	28162770	MONOMAC1	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.669284717708477	[225]	[411]	6	hSpCas9	negative selection	12075349
143942503	143942526	6	-	28162770	MONOMAC1	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.24747785329612393	[326]	[444]	2	hSpCas9	negative selection	12075350
143942437	143942460	6	+	28162770	MONOMAC1	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-0.559606926444262	[197]	[153]	-5	hSpCas9	negative selection	12075351
143942399	143942422	6	+	28162770	MONOMAC1	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	-0.08575351352580896	[211]	[228]	0	hSpCas9	negative selection	12075352
143942383	143942406	6	+	28162770	MONOMAC1	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	-1.1970368470595536	[91]	[45]	-7	hSpCas9	negative selection	12075353
143941935	143941958	6	+	28162770	OCIAML2	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	-2.9401151085433814	[17]	[12]	-9	hSpCas9	negative selection	12244710
143942275	143942298	6	+	28162770	OCIAML2	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	0.5405974301810929	[31]	[257]	5	hSpCas9	negative selection	12244711
143941924	143941947	6	+	28162770	OCIAML2	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-3.470629825242162	[13]	[6]	-9	hSpCas9	negative selection	12244712
143942473	143942496	6	-	28162770	OCIAML2	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	-0.33425738351087547	[57]	[254]	-3	hSpCas9	negative selection	12244713
143942308	143942331	6	-	28162770	OCIAML2	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	1.1598473347313636	[12]	[160]	9	hSpCas9	negative selection	12244714
143941558	143941581	6	+	28162770	OCIAML2	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.38044647424476075	[64]	[468]	3	hSpCas9	negative selection	12244715
143942503	143942526	6	-	28162770	OCIAML2	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.23288928583090307	[71]	[468]	2	hSpCas9	negative selection	12244716
143942437	143942460	6	+	28162770	OCIAML2	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	-0.0827041715805587	[46]	[245]	0	hSpCas9	negative selection	12244717
143942399	143942422	6	+	28162770	OCIAML2	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	-0.06254508660508451	[64]	[344]	0	hSpCas9	negative selection	12244718
143942383	143942406	6	+	28162770	OCIAML2	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	0.3367250968154429	[28]	[202]	3	hSpCas9	negative selection	12244719
143941935	143941958	6	+	28162770	OCIAML3	viability	GGAGAGCCAGGGGATACCGAGGG	PLAGL1	ENSG00000118495	0.939424559756911	[18]	[109]	7	hSpCas9	negative selection	12414076
143942275	143942298	6	+	28162770	OCIAML3	viability	ATCCTGTGTGGACCACCAGGTGG	PLAGL1	ENSG00000118495	-0.7305096402290252	[71]	[130]	-5	hSpCas9	negative selection	12414077
143941924	143941947	6	+	28162770	OCIAML3	viability	GGGGTGGCGGAGGAGAGCCAGGG	PLAGL1	ENSG00000118495	-2.4134353946823426	[29]	[16]	-9	hSpCas9	negative selection	12414078
143942473	143942496	6	-	28162770	OCIAML3	viability	GAGGCACCTGGCCCTCCATGCGG	PLAGL1	ENSG00000118495	0.11540223132148159	[73]	[241]	1	hSpCas9	negative selection	12414079
143942308	143942331	6	-	28162770	OCIAML3	viability	AAGATGCTTCTACACCCGGAAGG	PLAGL1	ENSG00000118495	0.6565358213264338	[28]	[137]	6	hSpCas9	negative selection	12414080
143941558	143941581	6	+	28162770	OCIAML3	viability	GCCCCAGACAGCTTAACCTGTGG	PLAGL1	ENSG00000118495	0.21763464013653933	[95]	[336]	2	hSpCas9	negative selection	12414081
143942503	143942526	6	-	28162770	OCIAML3	viability	GAAGAAGTACAACACCATGCTGG	PLAGL1	ENSG00000118495	0.34033293356937655	[117]	[450]	3	hSpCas9	negative selection	12414082
143942437	143942460	6	+	28162770	OCIAML3	viability	GGGCACAGACCCCACAGGTGAGG	PLAGL1	ENSG00000118495	0.16363152210679266	[96]	[327]	1	hSpCas9	negative selection	12414083
143942399	143942422	6	+	28162770	OCIAML3	viability	GAGGTGGTCCAGTAGCACCTCGG	PLAGL1	ENSG00000118495	0.10959935689561218	[104]	[341]	1	hSpCas9	negative selection	12414084
143942383	143942406	6	+	28162770	OCIAML3	viability	CTTCCGCATGGGCTTTGAGGTGG	PLAGL1	ENSG00000118495	-0.6085072100192782	[49]	[98]	-5	hSpCas9	negative selection	12414085