Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5578
• Symbol: PRKCA
• Description: protein kinase C alpha

DataSource: http://genomecrispr.dkfz.de/#!/results/PRKCA

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
66302850	66302873	17	-	26472758	Jiyoye	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	0.2101385344463197	[187]	[163]	1	hSpCas9	negative selection	127392
66735554	66735577	17	+	26472758	Jiyoye	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	0.538419914784126	[62]	[68]	4	hSpCas9	negative selection	127393
66302935	66302958	17	+	26472758	Jiyoye	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	-0.029264594505194585	[248]	[183]	0	hSpCas9	negative selection	127394
66645437	66645460	17	+	26472758	Jiyoye	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	0.44539470373636375	[148]	[152]	3	hSpCas9	negative selection	127395
66687228	66687251	17	+	26472758	Jiyoye	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.8204253308333357	[184]	[78]	-5	hSpCas9	negative selection	127396
66738779	66738802	17	+	26472758	Jiyoye	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	0.4071753815058735	[80]	[80]	3	hSpCas9	negative selection	127397
66742685	66742708	17	+	26472758	Jiyoye	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	1.1441409756720795	[35]	[59]	7	hSpCas9	negative selection	127398
66688389	66688412	17	-	26472758	Jiyoye	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-3.293264336635219	[51]	[3]	-9	hSpCas9	negative selection	127399
66688427	66688450	17	-	26472758	Jiyoye	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	0.6613588697574017	[108]	[129]	5	hSpCas9	negative selection	127400
66735488	66735511	17	+	26472758	Jiyoye	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	-0.3353283962017629	[86]	[51]	-2	hSpCas9	negative selection	127401
66302850	66302873	17	-	26472758	KBM7	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	0.41568228979671074	[676,538]	[420,340]	4	hSpCas9	negative selection	318510
66735554	66735577	17	+	26472758	KBM7	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	0.08983103428030054	[452,240]	[167,169]	0	hSpCas9	negative selection	318511
66302935	66302958	17	+	26472758	KBM7	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	-0.2482427710599524	[1139,1100]	[568,333]	-2	hSpCas9	negative selection	318512
66645437	66645460	17	+	26472758	KBM7	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	-1.0290912824514509	[641,524]	[157,111]	-7	hSpCas9	negative selection	318513
66687228	66687251	17	+	26472758	KBM7	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.44639398298462907	[227,235]	[78,81]	-4	hSpCas9	negative selection	318514
66738779	66738802	17	+	26472758	KBM7	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	-0.27901324758833956	[563,240]	[162,138]	-3	hSpCas9	negative selection	318515
66742685	66742708	17	+	26472758	KBM7	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	-0.11252442806057603	[315,571]	[251,152]	-1	hSpCas9	negative selection	318516
66688389	66688412	17	-	26472758	KBM7	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.6183998019802699	[195,115]	[22,67]	-5	hSpCas9	negative selection	318517
66688427	66688450	17	-	26472758	KBM7	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	0.6387989770628477	[574,640]	[529,377]	7	hSpCas9	negative selection	318518
66735488	66735511	17	+	26472758	KBM7	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	0.6351222822953081	[210,240]	[214,123]	7	hSpCas9	negative selection	318519
66302850	66302873	17	-	26472758	Raji	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	-0.0011409214045694505	[344]	[79]	0	hSpCas9	negative selection	509628
66735554	66735577	17	+	26472758	Raji	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	0.3324500910083731	[153]	[44]	3	hSpCas9	negative selection	509629
66302935	66302958	17	+	26472758	Raji	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	0.6155304390439246	[359]	[127]	6	hSpCas9	negative selection	509630
66645437	66645460	17	+	26472758	Raji	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	-0.46896583504284883	[166]	[27]	-4	hSpCas9	negative selection	509631
66687228	66687251	17	+	26472758	Raji	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.8666212560934561	[109]	[13]	-6	hSpCas9	negative selection	509632
66738779	66738802	17	+	26472758	Raji	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	1.7428111030777433	[102]	[79]	9	hSpCas9	negative selection	509633
66742685	66742708	17	+	26472758	Raji	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	-0.43058148581038735	[150]	[25]	-4	hSpCas9	negative selection	509634
66688389	66688412	17	-	26472758	Raji	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.013631865587766523	[86]	[19]	0	hSpCas9	negative selection	509635
66688427	66688450	17	-	26472758	Raji	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	0.19592020997525691	[236]	[62]	1	hSpCas9	negative selection	509636
66735488	66735511	17	+	26472758	Raji	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	0.6699782230663012	[129]	[47]	6	hSpCas9	negative selection	509637
66302850	66302873	17	-	26472758	K562	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	0.3763615982645397	[448]	[491]	3	hSpCas9	negative selection	700746
66735554	66735577	17	+	26472758	K562	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	0.07310049092426829	[258]	[229]	0	hSpCas9	negative selection	700747
66302935	66302958	17	+	26472758	K562	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	0.34680594564593914	[774]	[831]	2	hSpCas9	negative selection	700748
66645437	66645460	17	+	26472758	K562	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	-1.284181330435597	[501]	[173]	-6	hSpCas9	negative selection	700749
66687228	66687251	17	+	26472758	K562	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	0.3675138586383934	[246]	[268]	3	hSpCas9	negative selection	700750
66738779	66738802	17	+	26472758	K562	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	0.6158998609585509	[268]	[347]	5	hSpCas9	negative selection	700751
66742685	66742708	17	+	26472758	K562	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	-0.6756129676301379	[385]	[203]	-4	hSpCas9	negative selection	700752
66688389	66688412	17	-	26472758	K562	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.425865599003979	[96]	[109]	3	hSpCas9	negative selection	700753
66688427	66688450	17	-	26472758	K562	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	0.15432526144549372	[445]	[418]	1	hSpCas9	negative selection	700754
66735488	66735511	17	+	26472758	K562	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	1.055657084211279	[158]	[278]	8	hSpCas9	negative selection	700755
66302902	66302925	17	+	26627737	DLD1	viability	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.4237642073234076	[1132]	[375,532,512]	4	hSpCas9	negative selection	799421
66687222	66687245	17	-	26627737	DLD1	viability	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	0.8090274200854213	[250]	[97,252,75]	7	hSpCas9	negative selection	799425
66688389	66688412	17	-	26627737	DLD1	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.05885132572666074	[177]	[58,22,85]	0	hSpCas9	negative selection	799426
66688985	66689008	17	+	26627737	DLD1	viability	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-2.033306588167839	[369]	[8,61,16]	-9	hSpCas9	negative selection	799427
66732703	66732726	17	-	26627737	DLD1	viability	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	-0.11052673519333944	[315]	[86,97,89]	-1	hSpCas9	negative selection	799428
66735484	66735507	17	+	26627737	DLD1	viability	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	0.38211563657280934	[842]	[271,309,432]	4	hSpCas9	negative selection	799429
66302902	66302925	17	+	26627737	GBM cells	viability after 5 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.3036405513495666	[666]	[450,431]	5	hSpCas9	negative selection	881736
66687222	66687245	17	-	26627737	GBM cells	viability after 5 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-0.6478293036049804	[148]	[62,38]	-8	hSpCas9	negative selection	881740
66688389	66688412	17	-	26627737	GBM cells	viability after 5 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.021358932643580353	[87]	[45,46]	0	hSpCas9	negative selection	881741
66688985	66689008	17	+	26627737	GBM cells	viability after 5 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.15101135044599678	[146]	[84,56]	-2	hSpCas9	negative selection	881742
66732703	66732726	17	-	26627737	GBM cells	viability after 5 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	0.42247583094269847	[143]	[100,105]	6	hSpCas9	negative selection	881743
66735484	66735507	17	+	26627737	GBM cells	viability after 5 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	0.7094360760219727	[194]	[172,168]	8	hSpCas9	negative selection	881744
66302902	66302925	17	+	26627737	GBM cells	viability after 13 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.35024122878257113	[666]	[446,472]	4	hSpCas9	negative selection	964051
66687222	66687245	17	-	26627737	GBM cells	viability after 13 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-0.23223542366328642	[148]	[59,75]	-3	hSpCas9	negative selection	964055
66688389	66688412	17	-	26627737	GBM cells	viability after 13 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.14397178014122303	[87]	[49,54]	1	hSpCas9	negative selection	964056
66688985	66689008	17	+	26627737	GBM cells	viability after 13 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.0859244866832728	[146]	[94,58]	-1	hSpCas9	negative selection	964057
66732703	66732726	17	-	26627737	GBM cells	viability after 13 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	0.08376260783401335	[143]	[100,67]	1	hSpCas9	negative selection	964058
66735484	66735507	17	+	26627737	GBM cells	viability after 13 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	0.11295712366309141	[194]	[125,104]	1	hSpCas9	negative selection	964059
66302902	66302925	17	+	26627737	GBM cells	viability after 21 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.5315013902389285	[666]	[528,518]	5	hSpCas9	negative selection	1046366
66687222	66687245	17	-	26627737	GBM cells	viability after 21 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-0.14933026696590357	[148]	[84,61]	-1	hSpCas9	negative selection	1046370
66688389	66688412	17	-	26627737	GBM cells	viability after 21 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.6293883027897786	[87]	[74,72]	6	hSpCas9	negative selection	1046371
66688985	66689008	17	+	26627737	GBM cells	viability after 21 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.12129417013093535	[146]	[86,60]	-1	hSpCas9	negative selection	1046372
66732703	66732726	17	-	26627737	GBM cells	viability after 21 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	0.3567270020158923	[143]	[95,103]	3	hSpCas9	negative selection	1046373
66735484	66735507	17	+	26627737	GBM cells	viability after 21 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	0.6995404818286843	[194]	[170,172]	7	hSpCas9	negative selection	1046374
66302902	66302925	17	+	26627737	RPE1	viability after 9 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.8647434219893265	[1480]	[942,716]	5	hSpCas9	negative selection	1128681
66687222	66687245	17	-	26627737	RPE1	viability after 9 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-1.8790472160109049	[907]	[92,56]	-8	hSpCas9	negative selection	1128685
66688389	66688412	17	-	26627737	RPE1	viability after 9 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.08104718711242909	[586]	[164,184]	0	hSpCas9	negative selection	1128686
66688985	66689008	17	+	26627737	RPE1	viability after 9 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.23857352935180398	[399]	[113,95]	-2	hSpCas9	negative selection	1128687
66732703	66732726	17	-	26627737	RPE1	viability after 9 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	-0.4695007238354525	[1068]	[218,270]	-3	hSpCas9	negative selection	1128688
66735484	66735507	17	+	26627737	RPE1	viability after 9 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	0.5142833667443838	[1014]	[352,583]	3	hSpCas9	negative selection	1128689
66302902	66302925	17	+	26627737	RPE1	viability after 12 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.4701127802268673	[1480]	[556,544]	3	hSpCas9	negative selection	1210996
66687222	66687245	17	-	26627737	RPE1	viability after 12 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-1.1312017173048534	[907]	[140,79]	-7	hSpCas9	negative selection	1211000
66688389	66688412	17	-	26627737	RPE1	viability after 12 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.4631028487030325	[586]	[145,292]	3	hSpCas9	negative selection	1211001
66688985	66689008	17	+	26627737	RPE1	viability after 12 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.9951490874461081	[399]	[33,74]	-6	hSpCas9	negative selection	1211002
66732703	66732726	17	-	26627737	RPE1	viability after 12 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	-0.012563653265898755	[1068]	[308,258]	0	hSpCas9	negative selection	1211003
66735484	66735507	17	+	26627737	RPE1	viability after 12 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	0.4193572759349447	[1014]	[370,357]	3	hSpCas9	negative selection	1211004
66302902	66302925	17	+	26627737	RPE1	viability after 15 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.6784475257002275	[1480]	[783,560]	4	hSpCas9	negative selection	1293311
66687222	66687245	17	-	26627737	RPE1	viability after 15 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-1.2860536719253224	[907]	[114,95]	-7	hSpCas9	negative selection	1293315
66688389	66688412	17	-	26627737	RPE1	viability after 15 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.033846314480462825	[586]	[57,277]	0	hSpCas9	negative selection	1293316
66688985	66689008	17	+	26627737	RPE1	viability after 15 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.7281311676938164	[399]	[50,84]	-4	hSpCas9	negative selection	1293317
66732703	66732726	17	-	26627737	RPE1	viability after 15 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	-0.360991239674717	[1068]	[237,232]	-2	hSpCas9	negative selection	1293318
66735484	66735507	17	+	26627737	RPE1	viability after 15 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	0.3677969744784077	[1014]	[426,315]	2	hSpCas9	negative selection	1293319
66302902	66302925	17	+	26627737	RPE1	viability after 18 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.6080822216900338	[1480]	[716,493]	4	hSpCas9	negative selection	1375626
66687222	66687245	17	-	26627737	RPE1	viability after 18 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-2.160377029113869	[907]	[63,44]	-8	hSpCas9	negative selection	1375630
66688389	66688412	17	-	26627737	RPE1	viability after 18 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.024175119712539495	[586]	[119,204]	0	hSpCas9	negative selection	1375631
66688985	66689008	17	+	26627737	RPE1	viability after 18 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.494879738549448	[399]	[64,88]	-3	hSpCas9	negative selection	1375632
66732703	66732726	17	-	26627737	RPE1	viability after 18 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	-0.23122594009867786	[1068]	[238,252]	-1	hSpCas9	negative selection	1375633
66735484	66735507	17	+	26627737	RPE1	viability after 18 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	0.05260872787403842	[1014]	[242,327]	0	hSpCas9	negative selection	1375634
66302902	66302925	17	+	26627737	HeLa	viability after 8 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.09087813847833126	[990]	[289,805,258]	0	hSpCas9	negative selection	1457941
66687222	66687245	17	-	26627737	HeLa	viability after 8 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	0.6712196857533638	[158]	[23,183,103]	6	hSpCas9	negative selection	1457945
66688389	66688412	17	-	26627737	HeLa	viability after 8 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.8928473291856798	[56]	[35,24,72]	7	hSpCas9	negative selection	1457946
66688985	66689008	17	+	26627737	HeLa	viability after 8 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	1.1595752109886592	[128]	[201,64,125]	8	hSpCas9	negative selection	1457947
66732703	66732726	17	-	26627737	HeLa	viability after 8 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	0.6587917333111384	[175]	[231,90,67]	5	hSpCas9	negative selection	1457948
66735484	66735507	17	+	26627737	HeLa	viability after 8 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	-0.9027248264411168	[623]	[267,112,85]	-7	hSpCas9	negative selection	1457949
66302902	66302925	17	+	26627737	HeLa	viability after 12 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.08130368679478783	[990]	[395,468,429]	0	hSpCas9	negative selection	1540256
66687222	66687245	17	-	26627737	HeLa	viability after 12 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	0.7087209310962382	[158]	[90,113,115]	6	hSpCas9	negative selection	1540260
66688389	66688412	17	-	26627737	HeLa	viability after 12 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	2.1696036035523503	[56]	[112,78,128]	9	hSpCas9	negative selection	1540261
66688985	66689008	17	+	26627737	HeLa	viability after 12 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	0.01979391223872029	[128]	[14,72,70]	0	hSpCas9	negative selection	1540262
66732703	66732726	17	-	26627737	HeLa	viability after 12 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	-0.9587448795027373	[175]	[20,25,65]	-7	hSpCas9	negative selection	1540263
66735484	66735507	17	+	26627737	HeLa	viability after 12 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	-1.0937731244243585	[623]	[75,112,172]	-7	hSpCas9	negative selection	1540264
66302902	66302925	17	+	26627737	HeLa	viability after 15 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.5817090844371196	[990]	[645,534,631]	5	hSpCas9	negative selection	1622571
66687222	66687245	17	-	26627737	HeLa	viability after 15 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	0.38337564890603004	[158]	[103,40,109]	3	hSpCas9	negative selection	1622575
66688389	66688412	17	-	26627737	HeLa	viability after 15 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	1.8037508922222925	[56]	[45,49,152]	9	hSpCas9	negative selection	1622576
66688985	66689008	17	+	26627737	HeLa	viability after 15 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.6709386319661108	[128]	[46,3,48]	-5	hSpCas9	negative selection	1622577
66732703	66732726	17	-	26627737	HeLa	viability after 15 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	0.9295912211415697	[175]	[171,87,149]	7	hSpCas9	negative selection	1622578
66735484	66735507	17	+	26627737	HeLa	viability after 15 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	-0.20355265655004456	[623]	[186,317,151]	-2	hSpCas9	negative selection	1622579
66302902	66302925	17	+	26627737	HeLa	viability after 18 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.5759980592573293	[990]	[431,438,631]	4	hSpCas9	negative selection	1704886
66687222	66687245	17	-	26627737	HeLa	viability after 18 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	0.369784925094123	[158]	[68,32,109]	3	hSpCas9	negative selection	1704890
66688389	66688412	17	-	26627737	HeLa	viability after 18 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	1.7421643257544652	[56]	[22,42,152]	9	hSpCas9	negative selection	1704891
66688985	66689008	17	+	26627737	HeLa	viability after 18 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.5791496033339867	[128]	[35,2,48]	-5	hSpCas9	negative selection	1704892
66732703	66732726	17	-	26627737	HeLa	viability after 18 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	0.886009086080683	[175]	[104,75,149]	6	hSpCas9	negative selection	1704893
66735484	66735507	17	+	26627737	HeLa	viability after 18 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	-0.21951176545016488	[623]	[120,262,151]	-2	hSpCas9	negative selection	1704894
66302902	66302925	17	+	26627737	HCT116	viability after 6 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.6463513502453591	[1221]	[446,219]	3	hSpCas9	negative selection	1787201
66687222	66687245	17	-	26627737	HCT116	viability after 6 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-0.3034995782447425	[228]	[72,4]	-2	hSpCas9	negative selection	1787205
66688389	66688412	17	-	26627737	HCT116	viability after 6 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.7467199506427271	[340]	[78,5]	-4	hSpCas9	negative selection	1787206
66688985	66689008	17	+	26627737	HCT116	viability after 6 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.36153223468622964	[576]	[194,1]	-2	hSpCas9	negative selection	1787207
66732703	66732726	17	-	26627737	HCT116	viability after 6 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	0.3181703122098588	[269]	[137,5]	1	hSpCas9	negative selection	1787208
66735484	66735507	17	+	26627737	HCT116	viability after 6 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	-0.01841592998216801	[287]	[103,11]	0	hSpCas9	negative selection	1787209
66302902	66302925	17	+	26627737	HCT116	viability after 8 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	-0.0217501898331256	[658]	[425,430,218]	0	hSpCas9	negative selection	1869516
66687222	66687245	17	-	26627737	HCT116	viability after 8 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	0.5820023687863296	[153]	[157,126,96]	6	hSpCas9	negative selection	1869520
66688389	66688412	17	-	26627737	HCT116	viability after 8 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.2468639961879744	[208]	[101,71,116]	-3	hSpCas9	negative selection	1869521
66688985	66689008	17	+	26627737	HCT116	viability after 8 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.7664042052722764	[192]	[70,77,38]	-7	hSpCas9	negative selection	1869522
66732703	66732726	17	-	26627737	HCT116	viability after 8 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	-0.35716284387344466	[176]	[94,76,56]	-4	hSpCas9	negative selection	1869523
66735484	66735507	17	+	26627737	HCT116	viability after 8 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	1.543280967439131	[126]	[176,196,236]	9	hSpCas9	negative selection	1869524
66302902	66302925	17	+	26627737	HCT116	viability after 9 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.6526242344819171	[1221]	[460,553]	5	hSpCas9	negative selection	1951831
66687222	66687245	17	-	26627737	HCT116	viability after 9 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-0.5964514621780366	[228]	[40,39]	-4	hSpCas9	negative selection	1951835
66688389	66688412	17	-	26627737	HCT116	viability after 9 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-2.3961633884122913	[340]	[23,11]	-9	hSpCas9	negative selection	1951836
66688985	66689008	17	+	26627737	HCT116	viability after 9 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-2.301549438355738	[576]	[4,51]	-9	hSpCas9	negative selection	1951837
66732703	66732726	17	-	26627737	HCT116	viability after 9 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	1.461136672402537	[269]	[312,107]	8	hSpCas9	negative selection	1951838
66735484	66735507	17	+	26627737	HCT116	viability after 9 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	2.4459022629730236	[287]	[499,354]	9	hSpCas9	negative selection	1951839
66302902	66302925	17	+	26627737	HCT116	viability after 12 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.03349265219041797	[658]	[362,328,369]	0	hSpCas9	negative selection	2034146
66687222	66687245	17	-	26627737	HCT116	viability after 12 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	0.715447181713715	[153]	[64,106,231]	6	hSpCas9	negative selection	2034150
66688389	66688412	17	-	26627737	HCT116	viability after 12 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.7943461964391101	[208]	[63,65,59]	-7	hSpCas9	negative selection	2034151
66688985	66689008	17	+	26627737	HCT116	viability after 12 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.6980608000466622	[192]	[56,101,29]	-6	hSpCas9	negative selection	2034152
66732703	66732726	17	-	26627737	HCT116	viability after 12 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	-0.22276717028155513	[176]	[83,89,64]	-2	hSpCas9	negative selection	2034153
66735484	66735507	17	+	26627737	HCT116	viability after 12 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	1.765123622488957	[126]	[297,130,242]	9	hSpCas9	negative selection	2034154
66302902	66302925	17	+	26627737	HCT116	viability after 15 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.053268830006534484	[658]	[382,408,384]	0	hSpCas9	negative selection	2116461
66687222	66687245	17	-	26627737	HCT116	viability after 15 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-0.13777560673761768	[153]	[56,74,105]	-1	hSpCas9	negative selection	2116465
66688389	66688412	17	-	26627737	HCT116	viability after 15 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.4373036568055719	[208]	[95,96,73]	-4	hSpCas9	negative selection	2116466
66688985	66689008	17	+	26627737	HCT116	viability after 15 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.5293040855508016	[192]	[46,121,57]	-5	hSpCas9	negative selection	2116467
66732703	66732726	17	-	26627737	HCT116	viability after 15 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	0.2735258425420152	[176]	[89,100,172]	2	hSpCas9	negative selection	2116468
66735484	66735507	17	+	26627737	HCT116	viability after 15 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	1.9511671380059625	[126]	[214,262,358]	9	hSpCas9	negative selection	2116469
66302902	66302925	17	+	26627737	HCT116	viability after 18 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.10359876723895045	[658]	[328,372,321]	0	hSpCas9	negative selection	2198776
66687222	66687245	17	-	26627737	HCT116	viability after 18 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	0.5322534524108747	[153]	[113,147,55]	4	hSpCas9	negative selection	2198780
66688389	66688412	17	-	26627737	HCT116	viability after 18 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.5601880484723116	[208]	[65,65,73]	-5	hSpCas9	negative selection	2198781
66688985	66689008	17	+	26627737	HCT116	viability after 18 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.22178399536782012	[192]	[59,156,14]	-2	hSpCas9	negative selection	2198782
66732703	66732726	17	-	26627737	HCT116	viability after 18 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	-0.29923925616435376	[176]	[61,77,67]	-3	hSpCas9	negative selection	2198783
66735484	66735507	17	+	26627737	HCT116	viability after 18 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	2.2673429621028776	[126]	[290,209,395]	9	hSpCas9	negative selection	2198784
66302863	66302886	17	+	24336569	HL60	viability	TTTCCCGGGCAACGACTCCACGG	PRKCA	ENSG00000154229	0.10756972376112062	[224]	[512]	1	hSpCas9	negative selection	2286402
66302872	66302895	17	+	24336569	HL60	viability	CAACGACTCCACGGCGTCTCAGG	PRKCA	ENSG00000154229	0.32457059226899476	[642]	[1703]	3	hSpCas9	negative selection	2286403
66302878	66302901	17	+	24336569	HL60	viability	CTCCACGGCGTCTCAGGACGTGG	PRKCA	ENSG00000154229	-0.6296761239192068	[842]	[1152]	-5	hSpCas9	negative selection	2286404
66302900	66302923	17	+	24336569	HL60	viability	GCCAACCGCTTCGCCCGCAAAGG	PRKCA	ENSG00000154229	0.049624234275299495	[1003]	[2198]	0	hSpCas9	negative selection	2286405
66302929	66302952	17	+	24336569	HL60	viability	GAGGCAGAAGAACGTGCACGAGG	PRKCA	ENSG00000154229	0.9877852074158328	[421]	[1770]	7	hSpCas9	negative selection	2286406
66302935	66302958	17	+	24336569	HL60	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	-0.13350563268499038	[1128]	[2177]	-1	hSpCas9	negative selection	2286407
66302959	66302982	17	-	24336569	HL60	viability	AGAAGCGCGCGATGAATTTGTGG	PRKCA	ENSG00000154229	0.4878429580440602	[802]	[2382]	4	hSpCas9	negative selection	2286408
66303012	66303035	17	-	24336569	HL60	viability	CGGCACCTACCAGATGAAGTCGG	PRKCA	ENSG00000154229	0.38924858097906345	[358]	[994]	3	hSpCas9	negative selection	2286409
66306106	66306129	17	+	24336569	HL60	viability	AAACAAGGCTTCCAGTGCCAAGG	PRKCA	ENSG00000154229	0.6043954525800057	[611]	[1968]	5	hSpCas9	negative selection	2286410
66306117	66306140	17	-	24336569	HL60	viability	GTGGTAGCTTACCTTGGCACTGG	PRKCA	ENSG00000154229	-0.4698588471383611	[1537]	[2349]	-4	hSpCas9	negative selection	2286411
66302863	66302886	17	+	24336569	KBM7	viability	TTTCCCGGGCAACGACTCCACGG	PRKCA	ENSG00000154229	0.4560920762003333	[328]	[1230]	4	hSpCas9	negative selection	2353579
66302872	66302895	17	+	24336569	KBM7	viability	CAACGACTCCACGGCGTCTCAGG	PRKCA	ENSG00000154229	0.932109416401692	[376]	[1961]	7	hSpCas9	negative selection	2353580
66302878	66302901	17	+	24336569	KBM7	viability	CTCCACGGCGTCTCAGGACGTGG	PRKCA	ENSG00000154229	0.4043800718510948	[504]	[1822]	4	hSpCas9	negative selection	2353581
66302900	66302923	17	+	24336569	KBM7	viability	GCCAACCGCTTCGCCCGCAAAGG	PRKCA	ENSG00000154229	0.4517686368423728	[830]	[3099]	4	hSpCas9	negative selection	2353582
66302929	66302952	17	+	24336569	KBM7	viability	GAGGCAGAAGAACGTGCACGAGG	PRKCA	ENSG00000154229	1.8819221180432808	[227]	[2291]	9	hSpCas9	negative selection	2353583
66302935	66302958	17	+	24336569	KBM7	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	0.5185619994350815	[678]	[2652]	5	hSpCas9	negative selection	2353584
66302959	66302982	17	-	24336569	KBM7	viability	AGAAGCGCGCGATGAATTTGTGG	PRKCA	ENSG00000154229	1.270182186720172	[483]	[3183]	9	hSpCas9	negative selection	2353585
66303012	66303035	17	-	24336569	KBM7	viability	CGGCACCTACCAGATGAAGTCGG	PRKCA	ENSG00000154229	1.493527114397549	[299]	[2303]	9	hSpCas9	negative selection	2353586
66306106	66306129	17	+	24336569	KBM7	viability	AAACAAGGCTTCCAGTGCCAAGG	PRKCA	ENSG00000154229	0.511337897483075	[560]	[2180]	5	hSpCas9	negative selection	2353587
66306117	66306140	17	-	24336569	KBM7	viability	GTGGTAGCTTACCTTGGCACTGG	PRKCA	ENSG00000154229	0.9206716986165959	[1041]	[5379]	7	hSpCas9	negative selection	2353588
66368418	66368441	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTCTCTGTCACCCAGGCTGG	PRKCA	ENSG00000154229	1.918629985265858	[203,15]	[169,3]	6	dCas9-VP64	positive selection	2406672
66312047	66312070	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGAGGTTGCAGTGAGCCAAAG	PRKCA	ENSG00000154229	1.1995393964604157	[18,52]	[7,28]	5	dCas9-VP64	positive selection	2409418
66639918	66639941	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCTGCCTCCCAG	PRKCA	ENSG00000154229	-2.007733074360467	[162,472]	[3,30]	-9	dCas9-VP64	positive selection	2423945
66433617	66433640	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCTGCCTCCCGG	PRKCA	ENSG00000154229	-2.007733074360467	[162,472]	[3,30]	-9	dCas9-VP64	positive selection	2423995
66481871	66481894	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTGGGTGGATCACAAGGTCGGG	PRKCA	ENSG00000154229	7.202920170586078	[87,43]	[405,4032]	9	dCas9-VP64	positive selection	2429560
66302711	66302734	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGGTGGCCGAGGTCGCGGCGAGG	PRKCA	ENSG00000154229	-0.0965556957518543	[40,7]	[5,2]	0	dCas9-VP64	positive selection	2431018
66302662	66302685	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGCTGGTGCTGCGCGGAGCGGG	PRKCA	ENSG00000154229	2.0011064056049905	[44,179]	[19,185]	7	dCas9-VP64	positive selection	2431019
66302614	66302637	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGTGAGCCTGGGGCCAGCGGG	PRKCA	ENSG00000154229	-0.1639581069864875	[104,237]	[43,21]	0	dCas9-VP64	positive selection	2431020
66346292	66346315	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCACCGTGTTAGCTAGGATGG	PRKCA	ENSG00000154229	-0.43622771658323056	[174,104]	[36,6]	-2	dCas9-VP64	positive selection	2433035
66771044	66771067	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGGCTGGAGTGCAGTGGGGG	PRKCA	ENSG00000154229	-1.2921060931449064	[66,2]	[3,0]	-7	dCas9-VP64	positive selection	2435154
66595532	66595555	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCCGCCTCCCAG	PRKCA	ENSG00000154229	-0.7325628323231226	[970,485]	[85,105]	-4	dCas9-VP64	positive selection	2435256
66549081	66549104	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCACCGTGCCGGG	PRKCA	ENSG00000154229	-0.779191386983709	[52,249]	[14,23]	-4	dCas9-VP64	positive selection	2445680
66592260	66592283	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATCGCTTGAACCCAAG	PRKCA	ENSG00000154229	-1.1949452889942442	[147,110]	[6,17]	-7	dCas9-VP64	positive selection	2450030
66551153	66551176	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGAGGATCACTTGAGGCCAGG	PRKCA	ENSG00000154229	3.7396651611807004	[3,72]	[11,226]	9	dCas9-VP64	positive selection	2451802
66350596	66350619	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCACCCTTGACCTCCCAGG	PRKCA	ENSG00000154229	1.9771960985489354	[459,700]	[75,968]	7	dCas9-VP64	positive selection	2453498
66497268	66497291	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGCGGATCACCTGAGGTCGAG	PRKCA	ENSG00000154229	8.572613315975907	[14,15]	[366,2389]	9	dCas9-VP64	positive selection	2455558
66368418	66368441	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTCTCTGTCACCCAGGCTGG	PRKCA	ENSG00000154229	-0.026856909013432545	[158,111]	[47,38]	0	dCas9-VP64	positive selection	2501927
66312047	66312070	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGAGGTTGCAGTGAGCCAAAG	PRKCA	ENSG00000154229	-0.6764771816619682	[119,87]	[20,20]	-6	dCas9-VP64	positive selection	2504673
66639918	66639941	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCTGCCTCCCAG	PRKCA	ENSG00000154229	2.233334387673139	[58,128]	[217,75]	8	dCas9-VP64	positive selection	2519200
66433617	66433640	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCTGCCTCCCGG	PRKCA	ENSG00000154229	2.233334387673139	[58,128]	[217,75]	8	dCas9-VP64	positive selection	2519250
66481871	66481894	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTGGGTGGATCACAAGGTCGGG	PRKCA	ENSG00000154229	1.0563740175773226	[49,79]	[37,48]	6	dCas9-VP64	positive selection	2524815
66302711	66302734	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGGTGGCCGAGGTCGCGGCGAGG	PRKCA	ENSG00000154229	-0.34220862738173174	[32,30]	[7,7]	-3	dCas9-VP64	positive selection	2526273
66302662	66302685	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGCTGGTGCTGCGCGGAGCGGG	PRKCA	ENSG00000154229	0.4105952990847166	[68,32]	[36,7]	3	dCas9-VP64	positive selection	2526274
66302614	66302637	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGTGAGCCTGGGGCCAGCGGG	PRKCA	ENSG00000154229	7.464764349531096	[99,68]	[10168,12]	9	dCas9-VP64	positive selection	2526275
66346292	66346315	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCACCGTGTTAGCTAGGATGG	PRKCA	ENSG00000154229	1.4735482921306557	[116,143]	[227,15]	8	dCas9-VP64	positive selection	2528290
66771044	66771067	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGGCTGGAGTGCAGTGGGGG	PRKCA	ENSG00000154229	0.4307409852930557	[33,0]	[13,0]	3	dCas9-VP64	positive selection	2530409
66595532	66595555	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCCGCCTCCCAG	PRKCA	ENSG00000154229	0.3709996490739482	[598,467]	[394,67]	3	dCas9-VP64	positive selection	2530511
66549081	66549104	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCACCGTGCCGGG	PRKCA	ENSG00000154229	0.389783500937638	[291,598]	[109,262]	3	dCas9-VP64	positive selection	2540935
66592260	66592283	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATCGCTTGAACCCAAG	PRKCA	ENSG00000154229	1.2597172262171965	[381,372]	[459,141]	7	dCas9-VP64	positive selection	2545285
66551153	66551176	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGAGGATCACTTGAGGCCAGG	PRKCA	ENSG00000154229	0.5989374680558959	[87,40]	[52,11]	4	dCas9-VP64	positive selection	2547057
66350596	66350619	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCACCCTTGACCTCCCAGG	PRKCA	ENSG00000154229	-0.13896238492127178	[332,394]	[87,125]	-1	dCas9-VP64	positive selection	2548753
66497268	66497291	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGCGGATCACCTGAGGTCGAG	PRKCA	ENSG00000154229	1.5525228181942226	[88,74]	[56,98]	8	dCas9-VP64	positive selection	2550813
66303003	66303026	17	+	27013184	SW480	treatment with recombinant TRAIL	GCCACTGCACCGACTTCATCTGG	PRKCA	ENSG00000154229	0.49434655509944236	[688,901]	[398,589]	2	hSpCas9	positive selection	2963704
66687129	66687152	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTAATCCCTATGGATCCAAACGG	PRKCA	ENSG00000154229	-0.22769164022934812	[3,3]	[1,3]	-3	hSpCas9	positive selection	3013657
66687229	66687252	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.5554209505039218	[2,3]	[0,2]	-7	hSpCas9	positive selection	3013658
66687129	66687152	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTAATCCCTATGGATCCAAACGG	PRKCA	ENSG00000154229	-0.24169401664062484	[3,3]	[3,1]	-4	hSpCas9	positive selection	3081515
66687229	66687252	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.4858732065855031	[2,2]	[2,0]	-7	hSpCas9	positive selection	3081516
66496273	66496296		-	24336571	A375	resistance to PLX after 7 days	AGGACTACTTACATCAGTGTCGG	PRKCA	ENSG00000154229	-0.3771551805671013	[11,8]	[7,7]	-9	hSpCas9	positive selection	3137781
66306117	66306140		-	24336571	A375	resistance to PLX after 7 days	GTGGTAGCTTACCTTGGCACTGG	PRKCA	ENSG00000154229	0.2308783375390332	[15,16]	[20,16]	6	hSpCas9	positive selection	3137782
66496273	66496296		-	24336571	A375	resistance to PLX after 14 days	AGGACTACTTACATCAGTGTCGG	PRKCA	ENSG00000154229	1.5274161110498021	[7,8]	[8,14]	9	hSpCas9	positive selection	3195574
66306117	66306140		-	24336571	A375	resistance to PLX after 14 days	GTGGTAGCTTACCTTGGCACTGG	PRKCA	ENSG00000154229	1.4869613235444583	[11,11]	[12,18]	9	hSpCas9	positive selection	3195575
66496273	66496296		-	24336571	A375	viability after 7 days	AGGACTACTTACATCAGTGTCGG	PRKCA	ENSG00000154229	-0.3758156357294656	[14]	[11,8]	-5	hSpCas9	negative selection	3253367
66306117	66306140		-	24336571	A375	viability after 7 days	GTGGTAGCTTACCTTGGCACTGG	PRKCA	ENSG00000154229	0.22838065801279483	[14]	[15,16]	3	hSpCas9	negative selection	3253368
66496273	66496296		-	24336571	A375	viability after 14 days	AGGACTACTTACATCAGTGTCGG	PRKCA	ENSG00000154229	-0.6602413776919522	[14]	[7,8]	-7	hSpCas9	negative selection	3311160
66306117	66306140		-	24336571	A375	viability after 14 days	GTGGTAGCTTACCTTGGCACTGG	PRKCA	ENSG00000154229	-0.2021911052776069	[14]	[11,11]	-2	hSpCas9	negative selection	3311161
66306091	66306114	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	1.0093986980022496	[75,75]	[0,0]	4	hSpCas9	positive selection	3387474
66496229	66496252	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAGAAAAAGTAACAAATTCATGG	PRKCA	ENSG00000154229	0.02850752094995433	[149,149]	[0,0]	0	hSpCas9	positive selection	3387475
66641373	66641396	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.7815927804794374	[88,88]	[0,0]	4	hSpCas9	positive selection	3387476
66687226	66687249	17	-	26780180	HT29	viability (Avana library 4 designs)	ACTGCGGATTTAGTGTGGAGCGG	PRKCA	ENSG00000154229	0.823552723645202	[]	[]	3	hSpCas9	negative selection	3451844
66688326	66688349	17	-	26780180	HT29	viability (Avana library 4 designs)	AGATTTCTACAGACAGTCGTCGG	PRKCA	ENSG00000154229	1.09715705295562	[]	[]	4	hSpCas9	negative selection	3451845
66687128	66687151	17	+	26780180	HT29	viability (Avana library 4 designs)	CTAATCCCTATGGATCCAAACGG	PRKCA	ENSG00000154229	0.43898221570669	[]	[]	1	hSpCas9	negative selection	3451846
66687228	66687251	17	+	26780180	HT29	viability (Avana library 4 designs)	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	1.93310393187744	[]	[]	7	hSpCas9	negative selection	3451847
66688326	66688349	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGATTTCTACAGACAGTCGTCGG	PRKCA	ENSG00000154229	-0.351949568070577	[]	[]	0	hSpCas9	negative selection	3547932
66687226	66687249	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGCGGATTTAGTGTGGAGCGG	PRKCA	ENSG00000154229	4.46470366737901	[]	[]	7	hSpCas9	negative selection	3547933
66687128	66687151	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAATCCCTATGGATCCAAACGG	PRKCA	ENSG00000154229	-12.3198696529061	[]	[]	-8	hSpCas9	negative selection	3547934
66687228	66687251	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-4.02592363593818	[]	[]	-4	hSpCas9	negative selection	3547935
66688326	66688349	17	-	26780180	A375	viability (Avana lentiGuide)	AGATTTCTACAGACAGTCGTCGG	PRKCA	ENSG00000154229	5.33674465444815	[]	[]	5	hSpCas9	negative selection	3656591
66687226	66687249	17	-	26780180	A375	viability (Avana lentiGuide)	ACTGCGGATTTAGTGTGGAGCGG	PRKCA	ENSG00000154229	-1.15931594491695	[]	[]	-2	hSpCas9	negative selection	3656592
66687128	66687151	17	+	26780180	A375	viability (Avana lentiGuide)	CTAATCCCTATGGATCCAAACGG	PRKCA	ENSG00000154229	-2.22374760469115	[]	[]	-4	hSpCas9	negative selection	3656593
66687228	66687251	17	+	26780180	A375	viability (Avana lentiGuide)	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	14.404685390035	[]	[]	8	hSpCas9	negative selection	3656594
66688326	66688349	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATTTCTACAGACAGTCGTCGG	PRKCA	ENSG00000154229	-0.2958981527334024	[5]	[3,4]	-4	hSpCas9	positive selection	3765198
66687226	66687249	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGCGGATTTAGTGTGGAGCGG	PRKCA	ENSG00000154229	0.17976625904380186	[5]	[5,5]	5	hSpCas9	positive selection	3765199
66687128	66687151	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAATCCCTATGGATCCAAACGG	PRKCA	ENSG00000154229	-0.803621113430053	[6]	[3,2]	-8	hSpCas9	positive selection	3765200
66687228	66687251	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-1.2000035549657246	[3]	[1,0]	-9	hSpCas9	positive selection	3765201
66688326	66688349	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATTTCTACAGACAGTCGTCGG	PRKCA	ENSG00000154229	-0.1733490060397248	[6]	[3,5]	-2	hSpCas9	positive selection	3873805
66687226	66687249	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGCGGATTTAGTGTGGAGCGG	PRKCA	ENSG00000154229	-0.41259500850777925	[5]	[2,3]	-5	hSpCas9	positive selection	3873806
66687128	66687151	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAATCCCTATGGATCCAAACGG	PRKCA	ENSG00000154229	0.20407009732759301	[5]	[6,4]	5	hSpCas9	positive selection	3873807
66687228	66687251	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.5064819002640861	[4]	[2,2]	-6	hSpCas9	positive selection	3873808
66641373	66641396	17	+	26780180	A375	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.75327119610857	[]	[]	3	hSpCas9	negative selection	3984253
66641430	66641453	17	+	26780180	A375	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	1.06581123758461	[]	[]	5	hSpCas9	negative selection	3984254
66496272	66496295	17	-	26780180	A375	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.630256937540772	[]	[]	2	hSpCas9	negative selection	3984255
66306091	66306114	17	+	26780180	A375	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	1.82903357686458	[]	[]	9	hSpCas9	negative selection	3984256
66641359	66641382	17	-	26780180	A375	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.35509446235798	[]	[]	0	hSpCas9	negative selection	3984257
66641373	66641396	17	+	26780180	HT29	viability (GeCKOv2 library)	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.84563934913725	[]	[]	3	hSpCas9	negative selection	4092219
66641430	66641453	17	+	26780180	HT29	viability (GeCKOv2 library)	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.350321156254797	[]	[]	1	hSpCas9	negative selection	4092220
66496272	66496295	17	-	26780180	HT29	viability (GeCKOv2 library)	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.715554673387224	[]	[]	2	hSpCas9	negative selection	4092221
66306091	66306114	17	+	26780180	HT29	viability (GeCKOv2 library)	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	2.75924083019188	[]	[]	9	hSpCas9	negative selection	4092222
66641359	66641382	17	-	26780180	HT29	viability (GeCKOv2 library)	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.538409858901566	[]	[]	1	hSpCas9	negative selection	4092223
66496273	66496296	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGACTACTTACATCAGTGTCGG	PRKCA	ENSG00000154229	0.42976542613660373	[2]	[1,3]	8	hSpCas9	positive selection	4162940
66306117	66306140	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGGTAGCTTACCTTGGCACTGG	PRKCA	ENSG00000154229	0.18748644639318707	[4]	[2,3]	5	hSpCas9	positive selection	4162941
66496273	66496296	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGACTACTTACATCAGTGTCGG	PRKCA	ENSG00000154229	0.9914154882606858	[4]	[4,0,3,4]	7	hSpCas9	positive selection	4226962
66306117	66306140	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGGTAGCTTACCTTGGCACTGG	PRKCA	ENSG00000154229	0.7818382653603403	[3]	[0,2,0,4]	5	hSpCas9	positive selection	4226963
66496272	66496295	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	-0.03336711315638688	[2]	[2,1]	0	hSpCas9	positive selection	4292168
66641430	66641453	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.08358719383134518	[3]	[3,1]	1	hSpCas9	positive selection	4292169
66641359	66641382	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.1278965148741737	[3]	[4,2]	2	hSpCas9	positive selection	4292170
66306091	66306114	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.23565283690494132	[3]	[3,0]	-5	hSpCas9	positive selection	4356426
66641373	66641396	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.19524655836254706	[2]	[3,0]	4	hSpCas9	positive selection	4356428
66496249	66496271	17	+	27760321	OCIAML3	viability	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	-0.06318393512672772	[457,450]	[229,485]	0	hSpCas9	negative selection	4430594
66645383	66645405	17	-	27760321	OCIAML3	viability	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	-1.3317087169559019	[375,358]	[86,149]	-8	hSpCas9	negative selection	4430595
66645457	66645479	17	+	27760321	OCIAML3	viability	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	0.6578853335968096	[209,169]	[273,179]	7	hSpCas9	negative selection	4430596
66688987	66689009	17	+	27760321	OCIAML3	viability	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	0.11310288536193523	[464,394]	[312,426]	1	hSpCas9	negative selection	4430597
66732759	66732781	17	-	27760321	OCIAML3	viability	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	0.39614525881109375	[634,514]	[546,642]	5	hSpCas9	negative selection	4430598
66496249	66496271	17	+	27760321	OCIAML2	viability	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	0.4807675417734987	[457,450]	[428,626]	6	hSpCas9	negative selection	4514057
66645383	66645405	17	-	27760321	OCIAML2	viability	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	-0.665671997727971	[375,358]	[172,206]	-6	hSpCas9	negative selection	4514058
66645457	66645479	17	+	27760321	OCIAML2	viability	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	-0.43554347706712715	[209,169]	[106,120]	-5	hSpCas9	negative selection	4514059
66688987	66689009	17	+	27760321	OCIAML2	viability	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	-0.6108271188570653	[464,394]	[204,255]	-6	hSpCas9	negative selection	4514060
66732759	66732781	17	-	27760321	OCIAML2	viability	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	0.7539131381153175	[634,514]	[781,777]	8	hSpCas9	negative selection	4514061
66496249	66496271	17	+	27760321	MV411	viability	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	0.8459628405353937	[457,450]	[460,659]	6	hSpCas9	negative selection	4597520
66645383	66645405	17	-	27760321	MV411	viability	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	-1.786218583565757	[375,358]	[81,52]	-8	hSpCas9	negative selection	4597521
66645457	66645479	17	+	27760321	MV411	viability	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	0.8019428298845014	[209,169]	[246,172]	6	hSpCas9	negative selection	4597522
66688987	66689009	17	+	27760321	MV411	viability	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	-0.39969107320719444	[464,394]	[169,280]	-3	hSpCas9	negative selection	4597523
66732759	66732781	17	-	27760321	MV411	viability	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	0.3701374885849872	[634,514]	[524,431]	2	hSpCas9	negative selection	4597524
66496249	66496271	17	+	27760321	HL60	viability	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	0.5163584764557022	[457,450]	[563,498]	6	hSpCas9	negative selection	4680983
66645383	66645405	17	-	27760321	HL60	viability	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	-1.0434126123783993	[375,358]	[140,150]	-7	hSpCas9	negative selection	4680984
66645457	66645479	17	+	27760321	HL60	viability	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	0.932163655782275	[209,169]	[213,379]	8	hSpCas9	negative selection	4680985
66688987	66689009	17	+	27760321	HL60	viability	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	0.18775637668645082	[464,394]	[405,390]	2	hSpCas9	negative selection	4680986
66732759	66732781	17	-	27760321	HL60	viability	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	0.27679504244956077	[634,514]	[467,669]	3	hSpCas9	negative selection	4680987
66496249	66496271	17	+	27760321	HT1080	viability	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	1.2135218080210948	[450,351]	[442,291]	6	hSpCas9	negative selection	4764446
66645383	66645405	17	-	27760321	HT1080	viability	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	-0.35181529595626976	[358,279]	[72,128]	-2	hSpCas9	negative selection	4764447
66645457	66645479	17	+	27760321	HT1080	viability	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	-1.1536278738092909	[169,132]	[50,0]	-4	hSpCas9	negative selection	4764448
66688987	66689009	17	+	27760321	HT1080	viability	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	-0.41141139375026364	[394,307]	[68,144]	-2	hSpCas9	negative selection	4764449
66732759	66732781	17	-	27760321	HT1080	viability	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	1.1908205949593307	[514,401]	[331,509]	6	hSpCas9	negative selection	4764450
66496249	66496271	17	+	27760321	HT29	viability after 7 days	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	-0.3550613997210055	[450,351]	[444,395,375]	-5	hSpCas9	negative selection	4847909
66645383	66645405	17	-	27760321	HT29	viability after 7 days	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	-1.0008786862943218	[358,279]	[241,245,134]	-8	hSpCas9	negative selection	4847910
66645457	66645479	17	+	27760321	HT29	viability after 7 days	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	0.0885904785380014	[169,132]	[146,239,224]	1	hSpCas9	negative selection	4847911
66688987	66689009	17	+	27760321	HT29	viability after 7 days	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	-0.37171057598057716	[394,307]	[262,359,409]	-5	hSpCas9	negative selection	4847912
66732759	66732781	17	-	27760321	HT29	viability after 7 days	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	0.25873189746725356	[514,401]	[637,625,836]	4	hSpCas9	negative selection	4847913
66496249	66496271	17	+	27760321	HT29	viability after 25 days	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	-0.1900246190643864	[450,351]	[534,386,260]	-2	hSpCas9	negative selection	4931372
66645383	66645405	17	-	27760321	HT29	viability after 25 days	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	-1.9226249743317898	[358,279]	[33,133,127]	-8	hSpCas9	negative selection	4931373
66645457	66645479	17	+	27760321	HT29	viability after 25 days	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	0.8668985549514603	[169,132]	[202,426,324]	8	hSpCas9	negative selection	4931374
66688987	66689009	17	+	27760321	HT29	viability after 25 days	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	0.07937082599454445	[394,307]	[221,494,584]	0	hSpCas9	negative selection	4931375
66732759	66732781	17	-	27760321	HT29	viability after 25 days	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	0.038473368424105536	[514,401]	[671,370,564]	0	hSpCas9	negative selection	4931376
66496249	66496271	17	+	27760321	HT29	viability after 22 days	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	0.0029519894954329884	[450,351]	[571,397,421]	0	hSpCas9	negative selection	5014835
66645383	66645405	17	-	27760321	HT29	viability after 22 days	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	-1.132497078749894	[358,279]	[74,255,176]	-7	hSpCas9	negative selection	5014836
66645457	66645479	17	+	27760321	HT29	viability after 22 days	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	0.11797627843698222	[169,132]	[242,223,100]	1	hSpCas9	negative selection	5014837
66688987	66689009	17	+	27760321	HT29	viability after 22 days	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	-0.08737585996907418	[394,307]	[327,417,402]	-1	hSpCas9	negative selection	5014838
66732759	66732781	17	-	27760321	HT29	viability after 22 days	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	0.09670572374992659	[514,401]	[509,720,469]	0	hSpCas9	negative selection	5014839
66496249	66496271	17	+	27760321	HT29	viability after 19 days	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	-0.08841449193631337	[450,351]	[650,360,310]	-1	hSpCas9	negative selection	5098298
66645383	66645405	17	-	27760321	HT29	viability after 19 days	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	-0.9335721565146877	[358,279]	[323,241,27]	-6	hSpCas9	negative selection	5098299
66645457	66645479	17	+	27760321	HT29	viability after 19 days	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	1.5758225187164008	[169,132]	[368,755,412]	9	hSpCas9	negative selection	5098300
66688987	66689009	17	+	27760321	HT29	viability after 19 days	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	-0.04902641722021881	[394,307]	[239,364,538]	0	hSpCas9	negative selection	5098301
66732759	66732781	17	-	27760321	HT29	viability after 19 days	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	0.4336317490752005	[514,401]	[1005,697,460]	4	hSpCas9	negative selection	5098302
66496249	66496271	17	+	27760321	HT29	viability after 16 days	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	-0.25020151360713144	[450,351]	[492,410,238]	-3	hSpCas9	negative selection	5181761
66645383	66645405	17	-	27760321	HT29	viability after 16 days	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	-1.384752848499076	[358,279]	[14,217,163]	-7	hSpCas9	negative selection	5181762
66645457	66645479	17	+	27760321	HT29	viability after 16 days	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	0.5501191048810303	[169,132]	[279,156,312]	6	hSpCas9	negative selection	5181763
66688987	66689009	17	+	27760321	HT29	viability after 16 days	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	-0.18690228902327854	[394,307]	[449,275,321]	-2	hSpCas9	negative selection	5181764
66732759	66732781	17	-	27760321	HT29	viability after 16 days	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	0.3469578935773886	[514,401]	[815,639,516]	4	hSpCas9	negative selection	5181765
66496249	66496271	17	+	27760321	HT29	viability after 13 days	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	-0.6172346958313776	[450,351]	[151,365,387]	-6	hSpCas9	negative selection	5265224
66645383	66645405	17	-	27760321	HT29	viability after 13 days	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	-1.69118306814215	[358,279]	[135,54,150]	-8	hSpCas9	negative selection	5265225
66645457	66645479	17	+	27760321	HT29	viability after 13 days	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	0.6576233330023287	[169,132]	[286,338,209]	8	hSpCas9	negative selection	5265226
66688987	66689009	17	+	27760321	HT29	viability after 13 days	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	0.059265075434781406	[394,307]	[388,399,481]	0	hSpCas9	negative selection	5265227
66732759	66732781	17	-	27760321	HT29	viability after 13 days	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	-0.11169809064012101	[514,401]	[445,625,409]	-1	hSpCas9	negative selection	5265228
66496249	66496271	17	+	27760321	HT29	viability after 10 days	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	-0.20379749874080544	[450,351]	[525,520,264]	-3	hSpCas9	negative selection	5348687
66645383	66645405	17	-	27760321	HT29	viability after 10 days	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	-1.248852951317007	[358,279]	[204,220,80]	-8	hSpCas9	negative selection	5348688
66645457	66645479	17	+	27760321	HT29	viability after 10 days	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	0.24283607561298015	[169,132]	[365,108,193]	3	hSpCas9	negative selection	5348689
66688987	66689009	17	+	27760321	HT29	viability after 10 days	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	-0.31666769081873924	[394,307]	[348,513,201]	-4	hSpCas9	negative selection	5348690
66732759	66732781	17	-	27760321	HT29	viability after 10 days	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	0.17216875381053842	[514,401]	[576,735,624]	2	hSpCas9	negative selection	5348691
66496249	66496271	17	+	27760321	MOLM13	viability	CTTGTCCGGGTGCGGATAAGGG	PRKCA	ENSG00000154229	0.8523209045719093	[457,450]	[528,408]	6	hSpCas9	negative selection	5432150
66645383	66645405	17	-	27760321	MOLM13	viability	TTGTGAACGTTCATATCGCAGG	PRKCA	ENSG00000154229	0.7443483478511119	[375,358]	[134,528]	5	hSpCas9	negative selection	5432151
66645457	66645479	17	+	27760321	MOLM13	viability	AGGGGGCGGATTTACCTAAAGG	PRKCA	ENSG00000154229	0.16870749213450997	[209,169]	[20,203]	1	hSpCas9	negative selection	5432152
66688987	66689009	17	+	27760321	MOLM13	viability	CAACGTACCCATTCCGGAAGGG	PRKCA	ENSG00000154229	-0.20080732225423978	[464,394]	[265,162]	-1	hSpCas9	negative selection	5432153
66732759	66732781	17	-	27760321	MOLM13	viability	CGTGAGTTTCACTCGGTCAAGG	PRKCA	ENSG00000154229	-0.1647315967715257	[634,514]	[228,337]	-1	hSpCas9	negative selection	5432154
66302662	66302685	17	-	27661255	K562	viability	GGGCTGGTGCTGCGCGGAGCGGG	PRKCA	ENSG00000154229	0.04762168438627673	[914,1115]	[883,793]	1	dCas9-KRAB	negative selection	5504143
66302880	66302903	17	-	27661255	K562	viability	GGCCACGTCCTGAGACGCCGTGG	PRKCA	ENSG00000154229	-0.049086960690262305	[505,409]	[375,336]	-2	dCas9-KRAB	negative selection	5504144
66496272	66496295	17	-	27260156	BXPC3	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.1350616768592191	[290]	[197,367,457,323]	3	hSpCas9	negative selection	5564628
66641430	66641453	17	+	27260156	BXPC3	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.43917529920914344	[566]	[573,801,806,1086]	8	hSpCas9	negative selection	5564629
66641359	66641382	17	-	27260156	BXPC3	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.3917550294402776	[842]	[1299,1016,1189,1095]	8	hSpCas9	negative selection	5564630
66306091	66306114	17	+	27260156	BXPC3	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.5735415231920418	[521]	[401,264,349,460]	-8	hSpCas9	negative selection	5628886
66641373	66641396	17	+	27260156	BXPC3	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.21634404975459942	[252]	[258,242,399,339]	5	hSpCas9	negative selection	5628888
66496272	66496295	17	-	27260156	A673	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.03618928447451952	[290]	[407,294,343,394]	0	hSpCas9	negative selection	5685879
66641430	66641453	17	+	27260156	A673	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.26488695982889876	[566]	[878,721,825,854]	6	hSpCas9	negative selection	5685880
66641359	66641382	17	-	27260156	A673	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.2978343741115457	[842]	[1349,1243,1073,1324]	7	hSpCas9	negative selection	5685881
66306091	66306114	17	+	27260156	A673	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.8388698141737666	[521]	[411,362,302,328]	-9	hSpCas9	negative selection	5750137
66641373	66641396	17	+	27260156	A673	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.06610380796857873	[252]	[418,301,291,267]	1	hSpCas9	negative selection	5750139
66496272	66496295	17	-	27260156	A375	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.2671714632394362	[290]	[412,600,355,303]	4	hSpCas9	negative selection	5807130
66641430	66641453	17	+	27260156	A375	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.5119919649050408	[566]	[690,894,1168,1002]	7	hSpCas9	negative selection	5807131
66641359	66641382	17	-	27260156	A375	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.8157002727489056	[842]	[1891,1775,1654,1622]	9	hSpCas9	negative selection	5807132
66306091	66306114	17	+	27260156	A375	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.46694983996790457	[521]	[331,434,496,490]	-6	hSpCas9	negative selection	5871388
66641373	66641396	17	+	27260156	A375	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.8639353775957708	[252]	[416,715,621,430]	9	hSpCas9	negative selection	5871390
66496272	66496295	17	-	27260156	COLO741	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.028320997673896398	[290]	[569,321,268]	0	hSpCas9	negative selection	5928381
66641430	66641453	17	+	27260156	COLO741	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.31097561170455656	[566]	[976,1038,699]	6	hSpCas9	negative selection	5928382
66641359	66641382	17	-	27260156	COLO741	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.41886158127777007	[842]	[1606,1346,1380]	8	hSpCas9	negative selection	5928383
66306091	66306114	17	+	27260156	COLO741	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.9342934811670767	[521]	[329,327,383]	-9	hSpCas9	negative selection	5992639
66641373	66641396	17	+	27260156	COLO741	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.6179998475093947	[252]	[716,326,463]	9	hSpCas9	negative selection	5992641
66496272	66496295	17	-	27260156	CAL120	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	-0.2374785251166508	[290]	[321,373,228]	-3	hSpCas9	negative selection	6049632
66641430	66641453	17	+	27260156	CAL120	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.6267184067572851	[566]	[1547,1099,695]	8	hSpCas9	negative selection	6049633
66641359	66641382	17	-	27260156	CAL120	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.49865525653018694	[842]	[1806,1332,1356]	7	hSpCas9	negative selection	6049634
66306091	66306114	17	+	27260156	CAL120	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.5690948928291772	[521]	[644,233,464]	-7	hSpCas9	negative selection	6113890
66641373	66641396	17	+	27260156	CAL120	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.5885141726497454	[252]	[519,654,255]	8	hSpCas9	negative selection	6113892
66496272	66496295	17	-	27260156	CADOES1	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.29406832314074527	[290]	[419,280,294,330]	5	hSpCas9	negative selection	6170883
66641430	66641453	17	+	27260156	CADOES1	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.7309346936505562	[566]	[808,771,862,1063]	9	hSpCas9	negative selection	6170884
66641359	66641382	17	-	27260156	CADOES1	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.6090190710086232	[842]	[1171,1422,1270,906]	8	hSpCas9	negative selection	6170885
66306091	66306114	17	+	27260156	CADOES1	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.6809571337802064	[521]	[310,275,326,296]	-8	hSpCas9	negative selection	6235141
66641373	66641396	17	+	27260156	CADOES1	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.03920025582223341	[252]	[205,328,226,203]	0	hSpCas9	negative selection	6235143
66496272	66496295	17	-	27260156	EWS502	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.14939145871606718	[290]	[237,350,332,464]	2	hSpCas9	negative selection	6292134
66641430	66641453	17	+	27260156	EWS502	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.5186802142367296	[566]	[774,792,921,969]	8	hSpCas9	negative selection	6292135
66641359	66641382	17	-	27260156	EWS502	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.5549667348990532	[842]	[1068,1347,1354,1512]	8	hSpCas9	negative selection	6292136
66306091	66306114	17	+	27260156	EWS502	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-1.130035006950202	[521]	[279,233,187,307]	-9	hSpCas9	negative selection	6356392
66641373	66641396	17	+	27260156	EWS502	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.14593808224745664	[252]	[187,286,319,411]	2	hSpCas9	negative selection	6356394
66496272	66496295	17	-	27260156	EW8	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	-0.1503079983145187	[290]	[238,262,186,167]	-3	hSpCas9	negative selection	6413385
66641430	66641453	17	+	27260156	EW8	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.5618384045276373	[566]	[753,810,466,723]	8	hSpCas9	negative selection	6413386
66641359	66641382	17	-	27260156	EW8	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.6672997802483869	[842]	[1274,1243,846,1032]	9	hSpCas9	negative selection	6413387
66306091	66306114	17	+	27260156	EW8	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-1.1681718979368463	[521]	[216,267,141,136]	-9	hSpCas9	negative selection	6477643
66641373	66641396	17	+	27260156	EW8	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.615377474583462	[252]	[295,424,255,286]	9	hSpCas9	negative selection	6477645
66496272	66496295	17	-	27260156	CORL105	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.5891445375899685	[290]	[651,543,570,296]	9	hSpCas9	negative selection	6534636
66641430	66641453	17	+	27260156	CORL105	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.3407200212545548	[566]	[783,965,796,803]	6	hSpCas9	negative selection	6534637
66641359	66641382	17	-	27260156	CORL105	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.4923688013009062	[842]	[1458,1306,1233,1531]	8	hSpCas9	negative selection	6534638
66306091	66306114	17	+	27260156	CORL105	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.7883018882846303	[521]	[441,250,364,363]	-8	hSpCas9	negative selection	6598894
66641373	66641396	17	+	27260156	CORL105	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.2030201933824951	[252]	[292,386,402,287]	4	hSpCas9	negative selection	6598896
66496272	66496295	17	-	27260156	HS294T	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	-0.25549506099858543	[290]	[47,103,118,112]	-4	hSpCas9	negative selection	6655887
66641430	66641453	17	+	27260156	HS294T	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.61211197010651	[566]	[240,433,199,496]	7	hSpCas9	negative selection	6655888
66641359	66641382	17	-	27260156	HS294T	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.3330128946694222	[842]	[333,394,478,446]	4	hSpCas9	negative selection	6655889
66306091	66306114	17	+	27260156	HS294T	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.8173129483635437	[521]	[118,82,88,177]	-8	hSpCas9	negative selection	6720145
66641373	66641396	17	+	27260156	HS294T	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.14817847567722453	[252]	[94,83,124,135]	2	hSpCas9	negative selection	6720147
66496272	66496295	17	-	27260156	HCC44	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.48109672493273786	[290]	[646,238,705,336]	7	hSpCas9	negative selection	6777138
66641430	66641453	17	+	27260156	HCC44	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.5879604722839197	[566]	[1165,886,790,1001]	8	hSpCas9	negative selection	6777139
66641359	66641382	17	-	27260156	HCC44	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.3618180476967887	[842]	[1170,995,1557,1249]	6	hSpCas9	negative selection	6777140
66306091	66306114	17	+	27260156	HCC44	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.9720750476526672	[521]	[183,314,321,368]	-8	hSpCas9	negative selection	6841396
66641373	66641396	17	+	27260156	HCC44	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.3326590946531748	[252]	[413,248,496,323]	5	hSpCas9	negative selection	6841398
66496272	66496295	17	-	27260156	G402	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.5217662711210288	[290]	[309,821,522,377]	6	hSpCas9	negative selection	6898389
66641430	66641453	17	+	27260156	G402	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	1.2756793340193981	[566]	[1820,1290,1597,1967]	9	hSpCas9	negative selection	6898390
66641359	66641382	17	-	27260156	G402	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.8715358544038598	[842]	[1361,2135,1119,2796]	9	hSpCas9	negative selection	6898391
66306091	66306114	17	+	27260156	G402	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.8880883481140662	[521]	[465,658,170,125]	-8	hSpCas9	negative selection	6962647
66641373	66641396	17	+	27260156	G402	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	-0.3697281353628874	[252]	[351,240,134,242]	-5	hSpCas9	negative selection	6962649
66496272	66496295	17	-	27260156	L33	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	-0.26034982422805	[290]	[230,90,163,257]	-6	hSpCas9	negative selection	7019640
66641430	66641453	17	+	27260156	L33	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.13809243674445776	[566]	[718,320,292,524]	3	hSpCas9	negative selection	7019641
66641359	66641382	17	-	27260156	L33	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.2184718332956883	[842]	[880,414,573,1116]	5	hSpCas9	negative selection	7019642
66306091	66306114	17	+	27260156	L33	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-1.2151655107800134	[521]	[293,106,91,195]	-9	hSpCas9	negative selection	7083898
66641373	66641396	17	+	27260156	L33	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.19546493090624117	[252]	[286,124,208,234]	4	hSpCas9	negative selection	7083900
66496272	66496295	17	-	27260156	K562	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.20380988846019532	[290]	[217,375,378,221]	2	hSpCas9	negative selection	7140891
66641430	66641453	17	+	27260156	K562	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.5652992934123837	[566]	[372,605,597,1294]	7	hSpCas9	negative selection	7140892
66641359	66641382	17	-	27260156	K562	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.5262710146823129	[842]	[1252,812,741,1452]	6	hSpCas9	negative selection	7140893
66306091	66306114	17	+	27260156	K562	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.521593082048863	[521]	[195,394,285,396]	-6	hSpCas9	negative selection	7205149
66641373	66641396	17	+	27260156	K562	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.4688092489344489	[252]	[664,354,93,174]	6	hSpCas9	negative selection	7205151
66496272	66496295	17	-	27260156	HT29	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.11501386298028937	[290]	[428,408,364,337]	2	hSpCas9	negative selection	7262142
66641430	66641453	17	+	27260156	HT29	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.29959767345857435	[566]	[932,801,925,741]	6	hSpCas9	negative selection	7262143
66641359	66641382	17	-	27260156	HT29	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.3453465979281545	[842]	[1319,1329,1420,1149]	6	hSpCas9	negative selection	7262144
66306091	66306114	17	+	27260156	HT29	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.7123935288623942	[521]	[449,399,447,268]	-8	hSpCas9	negative selection	7326400
66641373	66641396	17	+	27260156	HT29	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.03294760764720983	[252]	[349,258,408,244]	0	hSpCas9	negative selection	7326402
66496272	66496295	17	-	27260156	MHHES1	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	-0.1601013387765926	[290]	[296,426,290,189]	-3	hSpCas9	negative selection	7383393
66641430	66641453	17	+	27260156	MHHES1	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.3673300062106254	[566]	[691,1106,995,557]	6	hSpCas9	negative selection	7383394
66641359	66641382	17	-	27260156	MHHES1	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.21130105648522135	[842]	[1112,1086,1110,1067]	4	hSpCas9	negative selection	7383395
66306091	66306114	17	+	27260156	MHHES1	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.9304439031865882	[521]	[487,263,323,194]	-9	hSpCas9	negative selection	7447651
66641373	66641396	17	+	27260156	MHHES1	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	-0.3318341881446569	[252]	[266,249,258,149]	-6	hSpCas9	negative selection	7447653
66496272	66496295	17	-	27260156	MEWO	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.13321310078239657	[290]	[392,293,226]	3	hSpCas9	negative selection	7504644
66641430	66641453	17	+	27260156	MEWO	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.2229372490298422	[566]	[801,540,549]	5	hSpCas9	negative selection	7504645
66641359	66641382	17	-	27260156	MEWO	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.25910807506986977	[842]	[1038,892,917]	5	hSpCas9	negative selection	7504646
66306091	66306114	17	+	27260156	MEWO	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-1.2632215801493258	[521]	[219,107,285]	-9	hSpCas9	negative selection	7568902
66641373	66641396	17	+	27260156	MEWO	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.305145683186006	[252]	[276,351,244]	6	hSpCas9	negative selection	7568904
66496272	66496295	17	-	27260156	LNCAPCLONEFGC	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.6743284587888002	[290]	[420,499,358,387]	9	hSpCas9	negative selection	7625895
66641430	66641453	17	+	27260156	LNCAPCLONEFGC	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.41444382412873726	[566]	[767,653,730,591]	6	hSpCas9	negative selection	7625896
66641359	66641382	17	-	27260156	LNCAPCLONEFGC	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.5925316768037427	[842]	[929,980,1395,1349]	8	hSpCas9	negative selection	7625897
66306091	66306114	17	+	27260156	LNCAPCLONEFGC	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-1.1322836569420494	[521]	[150,225,233,254]	-9	hSpCas9	negative selection	7690153
66641373	66641396	17	+	27260156	LNCAPCLONEFGC	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.21834887442315343	[252]	[200,214,380,290]	3	hSpCas9	negative selection	7690155
66496272	66496295	17	-	27260156	PANC0327	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.2450955787799461	[290]	[342,171,460,269]	3	hSpCas9	negative selection	7747146
66641430	66641453	17	+	27260156	PANC0327	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.2350843731032659	[566]	[334,826,719,437]	3	hSpCas9	negative selection	7747147
66641359	66641382	17	-	27260156	PANC0327	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.8224943458078577	[842]	[1292,1053,1362,1618]	9	hSpCas9	negative selection	7747148
66306091	66306114	17	+	27260156	PANC0327	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	0.010031960519335748	[521]	[941,386,427,159]	0	hSpCas9	negative selection	7811404
66641373	66641396	17	+	27260156	PANC0327	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	-0.061798383769191556	[252]	[266,155,176,272]	-1	hSpCas9	negative selection	7811406
66496272	66496295	17	-	27260156	NCIH2009	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.10576934528257453	[290]	[464,392,459]	1	hSpCas9	negative selection	7868397
66641430	66641453	17	+	27260156	NCIH2009	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.5364605376309913	[566]	[1357,947,1183]	7	hSpCas9	negative selection	7868398
66641359	66641382	17	-	27260156	NCIH2009	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.6017029869928323	[842]	[2295,1262,1909]	8	hSpCas9	negative selection	7868399
66306091	66306114	17	+	27260156	NCIH2009	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.6134972840113017	[521]	[425,654,334]	-6	hSpCas9	negative selection	7932655
66641373	66641396	17	+	27260156	NCIH2009	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	-0.12116301910044514	[252]	[290,310,365]	-2	hSpCas9	negative selection	7932657
66496272	66496295	17	-	27260156	NCIH1373	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.33887055714951075	[290]	[586,297,384,109]	3	hSpCas9	negative selection	7989648
66641430	66641453	17	+	27260156	NCIH1373	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.5149372898468475	[566]	[913,667,828,332]	5	hSpCas9	negative selection	7989649
66641359	66641382	17	-	27260156	NCIH1373	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	1.2047511436939196	[842]	[1515,2691,2246,545]	9	hSpCas9	negative selection	7989650
66306091	66306114	17	+	27260156	NCIH1373	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.45842735984384103	[521]	[573,240,210,194]	-4	hSpCas9	negative selection	8053906
66641373	66641396	17	+	27260156	NCIH1373	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.006798138627821859	[252]	[261,444,239,42]	0	hSpCas9	negative selection	8053908
66496272	66496295	17	-	27260156	PATU8902	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.09609738355175512	[290]	[363,564,492,273]	1	hSpCas9	negative selection	8110899
66641430	66641453	17	+	27260156	PATU8902	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.27774567150219087	[566]	[1297,834,704,1055]	3	hSpCas9	negative selection	8110900
66641359	66641382	17	-	27260156	PATU8902	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	1.0659623434549663	[842]	[1857,2599,2508,2891]	9	hSpCas9	negative selection	8110901
66306091	66306114	17	+	27260156	PATU8902	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.6490388323762419	[521]	[113,1282,211,293]	-6	hSpCas9	negative selection	8175157
66641373	66641396	17	+	27260156	PATU8902	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	-0.17798638455428706	[252]	[314,295,191,492]	-2	hSpCas9	negative selection	8175159
66496272	66496295	17	-	27260156	PANC1	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.3050300038023674	[290]	[352,444,190,272]	5	hSpCas9	negative selection	8232150
66641430	66641453	17	+	27260156	PANC1	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.38413080841030245	[566]	[651,696,616,585]	6	hSpCas9	negative selection	8232151
66641359	66641382	17	-	27260156	PANC1	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.26833361870808004	[842]	[830,1270,916,585]	4	hSpCas9	negative selection	8232152
66306091	66306114	17	+	27260156	PANC1	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.5887145121270057	[521]	[267,296,277,337]	-7	hSpCas9	negative selection	8296408
66641373	66641396	17	+	27260156	PANC1	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	-0.28406077067233304	[252]	[225,188,147,152]	-4	hSpCas9	negative selection	8296410
66496272	66496295	17	-	27260156	PANC0813	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.7669833698962418	[290]	[551,545,517,699]	9	hSpCas9	negative selection	8353401
66641430	66641453	17	+	27260156	PANC0813	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.024512671988022594	[566]	[860,543,685,636]	0	hSpCas9	negative selection	8353402
66641359	66641382	17	-	27260156	PANC0813	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.45971536037483895	[842]	[1616,1289,1286,1278]	7	hSpCas9	negative selection	8353403
66306091	66306114	17	+	27260156	PANC0813	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-1.006605285396681	[521]	[442,247,207,331]	-8	hSpCas9	negative selection	8417659
66641373	66641396	17	+	27260156	PANC0813	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	-0.0695522292957772	[252]	[296,157,357,318]	-1	hSpCas9	negative selection	8417661
66496272	66496295	17	-	27260156	RDES	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.21540950940046483	[290]	[313,359,397,507]	3	hSpCas9	negative selection	8474652
66641430	66641453	17	+	27260156	RDES	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.19433434940073357	[566]	[606,631,800,1004]	3	hSpCas9	negative selection	8474653
66641359	66641382	17	-	27260156	RDES	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.6042503552572691	[842]	[1274,1456,1489,1706]	8	hSpCas9	negative selection	8474654
66306091	66306114	17	+	27260156	RDES	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-1.1824332254297496	[521]	[208,210,344,312]	-9	hSpCas9	negative selection	8538910
66641373	66641396	17	+	27260156	RDES	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.0904956947679324	[252]	[216,379,221,440]	1	hSpCas9	negative selection	8538912
66496272	66496295	17	-	27260156	PC3	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.1158980697828782	[290]	[203,243,535,383]	2	hSpCas9	negative selection	8595903
66641430	66641453	17	+	27260156	PC3	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.09906876035654272	[566]	[481,565,906,564]	2	hSpCas9	negative selection	8595904
66641359	66641382	17	-	27260156	PC3	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.32404038127597046	[842]	[721,964,1566,1198]	7	hSpCas9	negative selection	8595905
66306091	66306114	17	+	27260156	PC3	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-1.0143976010828775	[521]	[116,201,580,304]	-9	hSpCas9	negative selection	8660161
66641373	66641396	17	+	27260156	PC3	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.19208120173860188	[252]	[118,319,523,335]	4	hSpCas9	negative selection	8660163
66496272	66496295	17	-	27260156	PATU8988T	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.20748207313793454	[290]	[411,278,269,334]	3	hSpCas9	negative selection	8717154
66641430	66641453	17	+	27260156	PATU8988T	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.20425526189157062	[566]	[575,460,768,706]	3	hSpCas9	negative selection	8717155
66641359	66641382	17	-	27260156	PATU8988T	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.3060583982964875	[842]	[926,979,1219,885]	5	hSpCas9	negative selection	8717156
66306091	66306114	17	+	27260156	PATU8988T	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-1.368004556000183	[521]	[91,225,215,254]	-9	hSpCas9	negative selection	8781412
66641373	66641396	17	+	27260156	PATU8988T	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	-0.1512992826048143	[252]	[114,286,323,153]	-3	hSpCas9	negative selection	8781414
66496272	66496295	17	-	27260156	T47D	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	-0.00012975194773845455	[290]	[363,280,383,330]	0	hSpCas9	negative selection	8838405
66641430	66641453	17	+	27260156	T47D	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.38591421139383997	[566]	[874,771,884,929]	7	hSpCas9	negative selection	8838406
66641359	66641382	17	-	27260156	T47D	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.43618451945527204	[842]	[1361,1314,1295,1343]	8	hSpCas9	negative selection	8838407
66306091	66306114	17	+	27260156	T47D	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.8431456024546908	[521]	[287,350,415,296]	-9	hSpCas9	negative selection	8902663
66641373	66641396	17	+	27260156	T47D	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	-0.049603236562270725	[252]	[298,236,314,291]	-1	hSpCas9	negative selection	8902665
66496272	66496295	17	-	27260156	SU8686	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	-0.05308673059100899	[290]	[185,241,314,403]	-1	hSpCas9	negative selection	8959656
66641430	66641453	17	+	27260156	SU8686	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.33911097010382196	[566]	[661,592,695,946]	6	hSpCas9	negative selection	8959657
66641359	66641382	17	-	27260156	SU8686	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.4200500357068886	[842]	[1126,914,1280,1181]	7	hSpCas9	negative selection	8959658
66306091	66306114	17	+	27260156	SU8686	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.8053279912599551	[521]	[274,179,392,365]	-8	hSpCas9	negative selection	9023914
66641373	66641396	17	+	27260156	SU8686	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.2898340642206586	[252]	[315,261,258,406]	5	hSpCas9	negative selection	9023916
66496272	66496295	17	-	27260156	SKES1	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.31727062657599403	[290]	[310,488,309,343]	6	hSpCas9	negative selection	9080907
66641430	66641453	17	+	27260156	SKES1	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.32076256137296655	[566]	[725,758,894,472]	6	hSpCas9	negative selection	9080908
66641359	66641382	17	-	27260156	SKES1	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.45777072227740767	[842]	[1469,1167,1189,859]	8	hSpCas9	negative selection	9080909
66306091	66306114	17	+	27260156	SKES1	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-1.2910596449008054	[521]	[271,249,213,134]	-9	hSpCas9	negative selection	9145165
66641373	66641396	17	+	27260156	SKES1	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.37745847349520534	[252]	[485,279,289,274]	7	hSpCas9	negative selection	9145167
66496272	66496295	17	-	27260156	TOV112D	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.15799344522149972	[290]	[270,386,260,389]	3	hSpCas9	negative selection	9202158
66641430	66641453	17	+	27260156	TOV112D	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.3409175928015643	[566]	[578,827,663,816]	6	hSpCas9	negative selection	9202159
66641359	66641382	17	-	27260156	TOV112D	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.6112301053877265	[842]	[1315,1563,1183,1165]	9	hSpCas9	negative selection	9202160
66306091	66306114	17	+	27260156	TOV112D	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-1.446329698757746	[521]	[189,366,132,121]	-9	hSpCas9	negative selection	9266416
66641373	66641396	17	+	27260156	TOV112D	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.18192470596982468	[252]	[195,454,249,281]	3	hSpCas9	negative selection	9266418
66496272	66496295	17	-	27260156	TC71	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	-0.010177112475456607	[290]	[334,256,330,314]	0	hSpCas9	negative selection	9323409
66641430	66641453	17	+	27260156	TC71	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.33231725841195636	[566]	[784,779,805,682]	7	hSpCas9	negative selection	9323410
66641359	66641382	17	-	27260156	TC71	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.20721967336067215	[842]	[952,894,1058,1281]	5	hSpCas9	negative selection	9323411
66306091	66306114	17	+	27260156	TC71	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.6158561328395149	[521]	[308,438,331,383]	-9	hSpCas9	negative selection	9387667
66641373	66641396	17	+	27260156	TC71	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.01904810274309454	[252]	[251,228,306,312]	0	hSpCas9	negative selection	9387669
66496272	66496295	17	-	27260156	TC32	viability	GGACTACTTACATCAGTGTCGGG	PRKCA	ENSG00000154229	0.24612274938180173	[290]	[341,269,299,381]	4	hSpCas9	negative selection	9444660
66641430	66641453	17	+	27260156	TC32	viability	CTCTATGGACTTATCCATCAAGG	PRKCA	ENSG00000154229	0.19617802516621047	[566]	[583,329,812,838]	3	hSpCas9	negative selection	9444661
66641359	66641382	17	-	27260156	TC32	viability	TTTGAACTTGTGCTTGCTCCTGG	PRKCA	ENSG00000154229	0.5052680283127631	[842]	[953,959,1359,1288]	8	hSpCas9	negative selection	9444662
66306091	66306114	17	+	27260156	TC32	viability	TTCAGGGGGTTTGGGAAACAAGG	PRKCA	ENSG00000154229	-0.9238793502051305	[521]	[274,156,434,216]	-9	hSpCas9	negative selection	9508918
66641373	66641396	17	+	27260156	TC32	viability	AAGTTCAAAATCCACACTTACGG	PRKCA	ENSG00000154229	0.2674657051444058	[252]	[249,266,283,339]	5	hSpCas9	negative selection	9508920
66302902	66302925	17	+	27869803	HPAFII	viability after 27 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.2074245905918134	[467]	[162,384,NaN]	1	hSpCas9	negative selection	9562451
66687222	66687245	17	-	27869803	HPAFII	viability after 27 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-0.5541695436851883	[113]	[54,28,NaN]	-4	hSpCas9	negative selection	9562455
66688389	66688412	17	-	27869803	HPAFII	viability after 27 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.766971570362976	[106]	[116,77,NaN]	6	hSpCas9	negative selection	9562456
66688985	66689008	17	+	27869803	HPAFII	viability after 27 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-3.520880046440591	[130]	[11,0,NaN]	-9	hSpCas9	negative selection	9562457
66732703	66732726	17	-	27869803	HPAFII	viability after 27 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	1.8300156759959125	[113]	[175,243,NaN]	9	hSpCas9	negative selection	9562458
66735484	66735507	17	+	27869803	HPAFII	viability after 27 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	1.2363842628315764	[258]	[286,348,NaN]	8	hSpCas9	negative selection	9562459
66302902	66302925	17	+	27869803	HPAFII	viability after 15 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.0571028389336119	[467]	[497,538,NaN]	0	hSpCas9	negative selection	9644900
66687222	66687245	17	-	27869803	HPAFII	viability after 15 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-0.21574094892902607	[113]	[123,93,NaN]	-2	hSpCas9	negative selection	9644904
66688389	66688412	17	-	27869803	HPAFII	viability after 15 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.6125848554241636	[106]	[300,97,NaN]	7	hSpCas9	negative selection	9644905
66688985	66689008	17	+	27869803	HPAFII	viability after 15 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-1.3740851938920942	[130]	[49,56,NaN]	-8	hSpCas9	negative selection	9644906
66732703	66732726	17	-	27869803	HPAFII	viability after 15 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	0.9361340904070187	[113]	[173,271,NaN]	8	hSpCas9	negative selection	9644907
66735484	66735507	17	+	27869803	HPAFII	viability after 15 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	0.3283733669954437	[258]	[367,337,NaN]	4	hSpCas9	negative selection	9644908
66302902	66302925	17	+	27869803	ASPC1	viability after 36 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.11014246177949572	[1393]	[746,513,372]	1	hSpCas9	negative selection	9727349
66687222	66687245	17	-	27869803	ASPC1	viability after 36 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	0.3341932406081946	[394]	[179,54,261]	3	hSpCas9	negative selection	9727353
66688389	66688412	17	-	27869803	ASPC1	viability after 36 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.3437760124287135	[367]	[55,90,139]	-4	hSpCas9	negative selection	9727354
66688985	66689008	17	+	27869803	ASPC1	viability after 36 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.711278892173448	[434]	[37,194,48]	-6	hSpCas9	negative selection	9727355
66732703	66732726	17	-	27869803	ASPC1	viability after 36 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	-0.30069079864954296	[323]	[17,74,155]	-3	hSpCas9	negative selection	9727356
66735484	66735507	17	+	27869803	ASPC1	viability after 36 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	-0.17178984645278797	[629]	[319,190,108]	-2	hSpCas9	negative selection	9727357
66302902	66302925	17	+	27869803	PATU8988S	viability after 35 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	-0.42485589018339665	[1292]	[351,423,NaN]	-4	hSpCas9	negative selection	9809798
66687222	66687245	17	-	27869803	PATU8988S	viability after 35 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-0.27410804087582097	[248]	[52,112,NaN]	-3	hSpCas9	negative selection	9809802
66688389	66688412	17	-	27869803	PATU8988S	viability after 35 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.20907099357849535	[202]	[97,90,NaN]	2	hSpCas9	negative selection	9809803
66688985	66689008	17	+	27869803	PATU8988S	viability after 35 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.258441991857559	[303]	[38,165,NaN]	-3	hSpCas9	negative selection	9809804
66732703	66732726	17	-	27869803	PATU8988S	viability after 35 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	0.47819447456878894	[252]	[115,167,NaN]	5	hSpCas9	negative selection	9809805
66735484	66735507	17	+	27869803	PATU8988S	viability after 35 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	0.5945394634035072	[530]	[290,354,NaN]	6	hSpCas9	negative selection	9809806
66302902	66302925	17	+	27869803	PATU8988S	viability after 31 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	-0.31929700492822266	[1292]	[282,578,NaN]	-4	hSpCas9	negative selection	9892247
66687222	66687245	17	-	27869803	PATU8988S	viability after 31 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-0.6086526449022056	[248]	[32,105,NaN]	-6	hSpCas9	negative selection	9892251
66688389	66688412	17	-	27869803	PATU8988S	viability after 31 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.30207296069020617	[202]	[90,110,NaN]	4	hSpCas9	negative selection	9892252
66688985	66689008	17	+	27869803	PATU8988S	viability after 31 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-0.3133417281808598	[303]	[64,138,NaN]	-4	hSpCas9	negative selection	9892253
66732703	66732726	17	-	27869803	PATU8988S	viability after 31 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	0.31651524918707663	[252]	[78,184,NaN]	4	hSpCas9	negative selection	9892254
66735484	66735507	17	+	27869803	PATU8988S	viability after 31 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	0.49998907103014734	[530]	[265,341,NaN]	6	hSpCas9	negative selection	9892255
66302902	66302925	17	+	27869803	HPAFII	viability after 35 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	-0.02840382082096715	[467]	[133,342,NaN]	0	hSpCas9	negative selection	9974696
66687222	66687245	17	-	27869803	HPAFII	viability after 35 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-2.169792272975876	[113]	[17,6,NaN]	-8	hSpCas9	negative selection	9974700
66688389	66688412	17	-	27869803	HPAFII	viability after 35 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.2641293994706515	[106]	[49,81,NaN]	1	hSpCas9	negative selection	9974701
66688985	66689008	17	+	27869803	HPAFII	viability after 35 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-5.438138267090675	[130]	[1,0,NaN]	-9	hSpCas9	negative selection	9974702
66732703	66732726	17	-	27869803	HPAFII	viability after 35 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	2.0930800335923125	[113]	[122,384,NaN]	9	hSpCas9	negative selection	9974703
66735484	66735507	17	+	27869803	HPAFII	viability after 35 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	2.14696778579739	[258]	[599,558,NaN]	9	hSpCas9	negative selection	9974704
66302902	66302925	17	+	27869803	HPAFII	viability after 31 days	CAACCGCTTCGCCCGCAAAGGGG	PRKCA	ENSG00000154229	0.23340193229982853	[467]	[191,435,NaN]	1	hSpCas9	negative selection	10057145
66687222	66687245	17	-	27869803	HPAFII	viability after 31 days	CGGATTTAGTGTGGAGCGGATGG	PRKCA	ENSG00000154229	-1.13763432529444	[113]	[41,14,NaN]	-6	hSpCas9	negative selection	10057149
66688389	66688412	17	-	27869803	HPAFII	viability after 31 days	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.38599977284763765	[106]	[88,66,NaN]	3	hSpCas9	negative selection	10057150
66688985	66689008	17	+	27869803	HPAFII	viability after 31 days	TACAACGTACCCATTCCGGAAGG	PRKCA	ENSG00000154229	-4.349195241168002	[130]	[5,0,NaN]	-9	hSpCas9	negative selection	10057151
66732703	66732726	17	-	27869803	HPAFII	viability after 31 days	CTGATGACTTTGTTGCCAGCAGG	PRKCA	ENSG00000154229	2.1765830798621812	[113]	[59,538,NaN]	9	hSpCas9	negative selection	10057152
66735484	66735507	17	+	27869803	HPAFII	viability after 31 days	CTCAGGTGATGCTTGCCGACAGG	PRKCA	ENSG00000154229	1.5346064486007143	[258]	[389,454,NaN]	9	hSpCas9	negative selection	10057153
66302850	66302873	17	-	28162770	P31FUJ	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	-0.08719688216747926	[225]	[249]	-1	hSpCas9	negative selection	10217049
66735554	66735577	17	+	28162770	P31FUJ	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	0.8274329027189915	[128]	[268]	8	hSpCas9	negative selection	10217050
66302935	66302958	17	+	28162770	P31FUJ	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	0.2136597476098434	[192]	[262]	2	hSpCas9	negative selection	10217051
66645437	66645460	17	+	28162770	P31FUJ	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	-0.2423882532435766	[150]	[149]	-2	hSpCas9	negative selection	10217052
66687228	66687251	17	+	28162770	P31FUJ	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.6113138276681083	[129]	[99]	-5	hSpCas9	negative selection	10217053
66738779	66738802	17	+	28162770	P31FUJ	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	1.1297678749703295	[90]	[233]	9	hSpCas9	negative selection	10217054
66742685	66742708	17	+	28162770	P31FUJ	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	-0.14043818626571913	[241]	[257]	-1	hSpCas9	negative selection	10217055
66688389	66688412	17	-	28162770	P31FUJ	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.0008701417880720985	[90]	[106]	0	hSpCas9	negative selection	10217056
66688427	66688450	17	-	28162770	P31FUJ	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	-0.3709331232778712	[459]	[417]	-3	hSpCas9	negative selection	10217057
66735488	66735511	17	+	28162770	P31FUJ	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	0.5598728223381151	[126]	[219]	6	hSpCas9	negative selection	10217058
66302850	66302873	17	-	28162770	TF1	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10386415
66735554	66735577	17	+	28162770	TF1	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10386416
66302935	66302958	17	+	28162770	TF1	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	NaN	[NaN]	[379]	1	hSpCas9	negative selection	10386417
66645437	66645460	17	+	28162770	TF1	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	NaN	[NaN]	[130]	1	hSpCas9	negative selection	10386418
66687228	66687251	17	+	28162770	TF1	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10386419
66738779	66738802	17	+	28162770	TF1	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	NaN	[NaN]	[52]	1	hSpCas9	negative selection	10386420
66742685	66742708	17	+	28162770	TF1	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10386421
66688389	66688412	17	-	28162770	TF1	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	NaN	[NaN]	[264]	1	hSpCas9	negative selection	10386422
66688427	66688450	17	-	28162770	TF1	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	NaN	[NaN]	[334]	1	hSpCas9	negative selection	10386423
66735488	66735511	17	+	28162770	TF1	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	NaN	[NaN]	[136]	1	hSpCas9	negative selection	10386424
66302850	66302873	17	-	28162770	SKM1	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	0.6703946839630779	[58]	[165]	6	hSpCas9	negative selection	10555781
66735554	66735577	17	+	28162770	SKM1	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	-0.47150445093787235	[39]	[50]	-4	hSpCas9	negative selection	10555782
66302935	66302958	17	+	28162770	SKM1	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	0.33180363805702995	[79]	[177]	3	hSpCas9	negative selection	10555783
66645437	66645460	17	+	28162770	SKM1	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	0.23143756093945503	[52]	[109]	2	hSpCas9	negative selection	10555784
66687228	66687251	17	+	28162770	SKM1	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.07280980152253991	[46]	[78]	0	hSpCas9	negative selection	10555785
66738779	66738802	17	+	28162770	SKM1	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	-0.2005133212757353	[38]	[59]	-2	hSpCas9	negative selection	10555786
66742685	66742708	17	+	28162770	SKM1	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	0.2849135058945065	[38]	[83]	2	hSpCas9	negative selection	10555787
66688389	66688412	17	-	28162770	SKM1	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.2914869813232257	[17]	[25]	-2	hSpCas9	negative selection	10555788
66688427	66688450	17	-	28162770	SKM1	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	0.8428141103883654	[81]	[259]	7	hSpCas9	negative selection	10555789
66735488	66735511	17	+	28162770	SKM1	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	0.5378942470643773	[29]	[76]	5	hSpCas9	negative selection	10555790
66302850	66302873	17	-	28162770	SKM1	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	0.6703946839630779	[58]	[165]	6	hSpCas9	negative selection	10725147
66735554	66735577	17	+	28162770	SKM1	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	-0.47150445093787235	[39]	[50]	-4	hSpCas9	negative selection	10725148
66302935	66302958	17	+	28162770	SKM1	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	0.33180363805702995	[79]	[177]	3	hSpCas9	negative selection	10725149
66645437	66645460	17	+	28162770	SKM1	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	0.23143756093945503	[52]	[109]	2	hSpCas9	negative selection	10725150
66687228	66687251	17	+	28162770	SKM1	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.07280980152253991	[46]	[78]	0	hSpCas9	negative selection	10725151
66738779	66738802	17	+	28162770	SKM1	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	-0.2005133212757353	[38]	[59]	-2	hSpCas9	negative selection	10725152
66742685	66742708	17	+	28162770	SKM1	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	0.2849135058945065	[38]	[83]	2	hSpCas9	negative selection	10725153
66688389	66688412	17	-	28162770	SKM1	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.2914869813232257	[17]	[25]	-2	hSpCas9	negative selection	10725154
66688427	66688450	17	-	28162770	SKM1	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	0.8428141103883654	[81]	[259]	7	hSpCas9	negative selection	10725155
66735488	66735511	17	+	28162770	SKM1	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	0.5378942470643773	[29]	[76]	5	hSpCas9	negative selection	10725156
66302850	66302873	17	-	28162770	PL21	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	1.3016209323552037	[246]	[264]	9	hSpCas9	negative selection	10894513
66735554	66735577	17	+	28162770	PL21	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	3.7776846436479934	[129]	[775]	9	hSpCas9	negative selection	10894514
66302935	66302958	17	+	28162770	PL21	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	-0.017337316433011285	[292]	[125]	0	hSpCas9	negative selection	10894515
66645437	66645460	17	+	28162770	PL21	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	1.3216031269749875	[147]	[160]	9	hSpCas9	negative selection	10894516
66687228	66687251	17	+	28162770	PL21	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-1.6906313157559214	[177]	[23]	-8	hSpCas9	negative selection	10894517
66738779	66738802	17	+	28162770	PL21	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	-0.8800307341946629	[147]	[34]	-6	hSpCas9	negative selection	10894518
66742685	66742708	17	+	28162770	PL21	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	0.12485148718508292	[176]	[83]	1	hSpCas9	negative selection	10894519
66688389	66688412	17	-	28162770	PL21	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.5368259796768862	[69]	[20]	-4	hSpCas9	negative selection	10894520
66688427	66688450	17	-	28162770	PL21	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	-0.1082419485600945	[264]	[106]	-1	hSpCas9	negative selection	10894521
66735488	66735511	17	+	28162770	PL21	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	-0.5599095927899272	[104]	[30]	-4	hSpCas9	negative selection	10894522
66302850	66302873	17	-	28162770	P31FUJ	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	-0.08719688216747926	[225]	[249]	-1	hSpCas9	negative selection	11063879
66735554	66735577	17	+	28162770	P31FUJ	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	0.8274329027189915	[128]	[268]	8	hSpCas9	negative selection	11063880
66302935	66302958	17	+	28162770	P31FUJ	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	0.2136597476098434	[192]	[262]	2	hSpCas9	negative selection	11063881
66645437	66645460	17	+	28162770	P31FUJ	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	-0.2423882532435766	[150]	[149]	-2	hSpCas9	negative selection	11063882
66687228	66687251	17	+	28162770	P31FUJ	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.6113138276681083	[129]	[99]	-5	hSpCas9	negative selection	11063883
66738779	66738802	17	+	28162770	P31FUJ	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	1.1297678749703295	[90]	[233]	9	hSpCas9	negative selection	11063884
66742685	66742708	17	+	28162770	P31FUJ	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	-0.14043818626571913	[241]	[257]	-1	hSpCas9	negative selection	11063885
66688389	66688412	17	-	28162770	P31FUJ	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.0008701417880720985	[90]	[106]	0	hSpCas9	negative selection	11063886
66688427	66688450	17	-	28162770	P31FUJ	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	-0.3709331232778712	[459]	[417]	-3	hSpCas9	negative selection	11063887
66735488	66735511	17	+	28162770	P31FUJ	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	0.5598728223381151	[126]	[219]	6	hSpCas9	negative selection	11063888
66302850	66302873	17	-	28162770	OCIAML5	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	0.16010814308210516	[117]	[237]	1	hSpCas9	negative selection	11233245
66735554	66735577	17	+	28162770	OCIAML5	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	0.28068863798777455	[82]	[181]	2	hSpCas9	negative selection	11233246
66302935	66302958	17	+	28162770	OCIAML5	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	1.3812471368497974	[93]	[441]	9	hSpCas9	negative selection	11233247
66645437	66645460	17	+	28162770	OCIAML5	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	0.6760335929014829	[68]	[198]	6	hSpCas9	negative selection	11233248
66687228	66687251	17	+	28162770	OCIAML5	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	1.8886906024645833	[37]	[253]	9	hSpCas9	negative selection	11233249
66738779	66738802	17	+	28162770	OCIAML5	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	-0.5119911292663751	[78]	[99]	-4	hSpCas9	negative selection	11233250
66742685	66742708	17	+	28162770	OCIAML5	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	0.13596078746992718	[120]	[239]	1	hSpCas9	negative selection	11233251
66688389	66688412	17	-	28162770	OCIAML5	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.3089242458374678	[69]	[101]	-2	hSpCas9	negative selection	11233252
66688427	66688450	17	-	28162770	OCIAML5	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	-0.28197734662437113	[259]	[385]	-2	hSpCas9	negative selection	11233253
66735488	66735511	17	+	28162770	OCIAML5	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	-0.24301845161852764	[98]	[150]	-2	hSpCas9	negative selection	11233254
66302850	66302873	17	-	28162770	EOL1	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	0.20222895336872992	[489]	[296]	1	hSpCas9	negative selection	11402611
66735554	66735577	17	+	28162770	EOL1	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	1.7355139471805174	[113]	[199]	9	hSpCas9	negative selection	11402612
66302935	66302958	17	+	28162770	EOL1	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	0.9732630566035626	[494]	[511]	8	hSpCas9	negative selection	11402613
66645437	66645460	17	+	28162770	EOL1	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	-1.0618631636815103	[316]	[79]	-6	hSpCas9	negative selection	11402614
66687228	66687251	17	+	28162770	EOL1	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.6012796050632894	[238]	[82]	-4	hSpCas9	negative selection	11402615
66738779	66738802	17	+	28162770	EOL1	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	-0.12952890118525814	[298]	[143]	-1	hSpCas9	negative selection	11402616
66742685	66742708	17	+	28162770	EOL1	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	0.47653294984541794	[235]	[172]	4	hSpCas9	negative selection	11402617
66688389	66688412	17	-	28162770	EOL1	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	2.516174002572701	[71]	[216]	9	hSpCas9	negative selection	11402618
66688427	66688450	17	-	28162770	EOL1	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	-0.763508222114725	[405]	[125]	-5	hSpCas9	negative selection	11402619
66735488	66735511	17	+	28162770	EOL1	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	1.1196781129025248	[144]	[165]	8	hSpCas9	negative selection	11402620
66302850	66302873	17	-	28162770	MOLM13	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	0.46058458092134547	[395]	[393]	3	hSpCas9	negative selection	11571977
66735554	66735577	17	+	28162770	MOLM13	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	-0.3692601427733788	[158]	[88]	-2	hSpCas9	negative selection	11571978
66302935	66302958	17	+	28162770	MOLM13	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	0.32043738033071556	[421]	[380]	2	hSpCas9	negative selection	11571979
66645437	66645460	17	+	28162770	MOLM13	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	-0.3005687600251643	[246]	[144]	-2	hSpCas9	negative selection	11571980
66687228	66687251	17	+	28162770	MOLM13	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.20254246136592696	[225]	[141]	-1	hSpCas9	negative selection	11571981
66738779	66738802	17	+	28162770	MOLM13	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	0.5966226956667816	[149]	[163]	4	hSpCas9	negative selection	11571982
66742685	66742708	17	+	28162770	MOLM13	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	-0.990401315688149	[315]	[114]	-5	hSpCas9	negative selection	11571983
66688389	66688412	17	-	28162770	MOLM13	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.39388880010080196	[119]	[113]	3	hSpCas9	negative selection	11571984
66688427	66688450	17	-	28162770	MOLM13	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	-0.3822151879723624	[547]	[303]	-2	hSpCas9	negative selection	11571985
66735488	66735511	17	+	28162770	MOLM13	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	1.1175048406079884	[159]	[250]	8	hSpCas9	negative selection	11571986
66302850	66302873	17	-	28162770	HEL	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	1.2194147215365523	[290]	[433]	9	hSpCas9	negative selection	11741343
66735554	66735577	17	+	28162770	HEL	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	-0.7657260133550006	[145]	[54]	-5	hSpCas9	negative selection	11741344
66302935	66302958	17	+	28162770	HEL	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	0.4105653898713235	[369]	[314]	3	hSpCas9	negative selection	11741345
66645437	66645460	17	+	28162770	HEL	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	0.8555874806659339	[194]	[225]	7	hSpCas9	negative selection	11741346
66687228	66687251	17	+	28162770	HEL	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	1.2632454495791803	[146]	[225]	9	hSpCas9	negative selection	11741347
66738779	66738802	17	+	28162770	HEL	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	1.0872201091716827	[193]	[263]	8	hSpCas9	negative selection	11741348
66742685	66742708	17	+	28162770	HEL	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	-0.5392590017425305	[269]	[118]	-4	hSpCas9	negative selection	11741349
66688389	66688412	17	-	28162770	HEL	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-1.500219121841686	[105]	[23]	-7	hSpCas9	negative selection	11741350
66688427	66688450	17	-	28162770	HEL	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	-0.6249894498244848	[430]	[178]	-4	hSpCas9	negative selection	11741351
66735488	66735511	17	+	28162770	HEL	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	0.7322369828394596	[124]	[132]	6	hSpCas9	negative selection	11741352
66302850	66302873	17	-	28162770	MV411	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	0.09483842550074573	[268]	[241]	0	hSpCas9	negative selection	11910709
66735554	66735577	17	+	28162770	MV411	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	0.6910442022583901	[99]	[135]	6	hSpCas9	negative selection	11910710
66302935	66302958	17	+	28162770	MV411	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	-0.9258940521027865	[317]	[140]	-6	hSpCas9	negative selection	11910711
66645437	66645460	17	+	28162770	MV411	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	-0.3770533141250182	[184]	[119]	-3	hSpCas9	negative selection	11910712
66687228	66687251	17	+	28162770	MV411	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-0.8563982602017648	[143]	[66]	-5	hSpCas9	negative selection	11910713
66738779	66738802	17	+	28162770	MV411	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	-0.28743971850207173	[183]	[126]	-2	hSpCas9	negative selection	11910714
66742685	66742708	17	+	28162770	MV411	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	-0.12730724254803538	[152]	[117]	-1	hSpCas9	negative selection	11910715
66688389	66688412	17	-	28162770	MV411	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	2.2309494279942066	[21]	[86]	9	hSpCas9	negative selection	11910716
66688427	66688450	17	-	28162770	MV411	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	-0.3201578179682928	[288]	[194]	-2	hSpCas9	negative selection	11910717
66735488	66735511	17	+	28162770	MV411	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	-0.21913024913615042	[75]	[54]	-2	hSpCas9	negative selection	11910718
66302850	66302873	17	-	28162770	MONOMAC1	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	1.5217814003963932	[143]	[473]	9	hSpCas9	negative selection	12080075
66735554	66735577	17	+	28162770	MONOMAC1	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	0.6960479490239344	[55]	[103]	6	hSpCas9	negative selection	12080076
66302935	66302958	17	+	28162770	MONOMAC1	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	-0.05264693772437873	[170]	[188]	0	hSpCas9	negative selection	12080077
66645437	66645460	17	+	28162770	MONOMAC1	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	0.4365355978862241	[106]	[165]	4	hSpCas9	negative selection	12080078
66687228	66687251	17	+	28162770	MONOMAC1	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	0.32379531624188684	[68]	[98]	3	hSpCas9	negative selection	12080079
66738779	66738802	17	+	28162770	MONOMAC1	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	-0.7323685800561093	[99]	[68]	-6	hSpCas9	negative selection	12080080
66742685	66742708	17	+	28162770	MONOMAC1	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	0.5606023153714023	[96]	[163]	5	hSpCas9	negative selection	12080081
66688389	66688412	17	-	28162770	MONOMAC1	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	0.8711346555820256	[30]	[64]	7	hSpCas9	negative selection	12080082
66688427	66688450	17	-	28162770	MONOMAC1	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	-0.24036427872365448	[168]	[163]	-2	hSpCas9	negative selection	12080083
66735488	66735511	17	+	28162770	MONOMAC1	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	0.45503984952013965	[55]	[87]	4	hSpCas9	negative selection	12080084
66302850	66302873	17	-	28162770	OCIAML2	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	0.48257596327889773	[46]	[363]	5	hSpCas9	negative selection	12249441
66735554	66735577	17	+	28162770	OCIAML2	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	1.2356389717011285	[18]	[247]	9	hSpCas9	negative selection	12249442
66302935	66302958	17	+	28162770	OCIAML2	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	-0.32125220120393455	[54]	[243]	-3	hSpCas9	negative selection	12249443
66645437	66645460	17	+	28162770	OCIAML2	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	-0.3276718714001181	[35]	[158]	-3	hSpCas9	negative selection	12249444
66687228	66687251	17	+	28162770	OCIAML2	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	0.39444059467173026	[20]	[152]	4	hSpCas9	negative selection	12249445
66738779	66738802	17	+	28162770	OCIAML2	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	0.7517625960942866	[26]	[251]	7	hSpCas9	negative selection	12249446
66742685	66742708	17	+	28162770	OCIAML2	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	0.8243312220449317	[26]	[264]	7	hSpCas9	negative selection	12249447
66688389	66688412	17	-	28162770	OCIAML2	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	-0.5831045545005737	[19]	[73]	-4	hSpCas9	negative selection	12249448
66688427	66688450	17	-	28162770	OCIAML2	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	0.23596211988052615	[35]	[234]	2	hSpCas9	negative selection	12249449
66735488	66735511	17	+	28162770	OCIAML2	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	1.4249009082018096	[16]	[252]	9	hSpCas9	negative selection	12249450
66302850	66302873	17	-	28162770	OCIAML3	viability	GCCCGGGAAAACGTCAGCCATGG	PRKCA	ENSG00000154229	-0.3442293311926362	[81]	[194]	-3	hSpCas9	negative selection	12418807
66735554	66735577	17	+	28162770	OCIAML3	viability	GGTGATTCAGGATGATGACGTGG	PRKCA	ENSG00000154229	0.14707406231427494	[34]	[116]	1	hSpCas9	negative selection	12418808
66302935	66302958	17	+	28162770	OCIAML3	viability	GAAGAACGTGCACGAGGTGAAGG	PRKCA	ENSG00000154229	-0.37161521898771527	[62]	[146]	-3	hSpCas9	negative selection	12418809
66645437	66645460	17	+	28162770	OCIAML3	viability	GAATGGATCACACTGAGAAGAGG	PRKCA	ENSG00000154229	0.5674557823699532	[37]	[169]	5	hSpCas9	negative selection	12418810
66687228	66687251	17	+	28162770	OCIAML3	viability	GCTCCACACTAAATCCGCAGTGG	PRKCA	ENSG00000154229	-1.09150729979498	[35]	[50]	-7	hSpCas9	negative selection	12418811
66738779	66738802	17	+	28162770	OCIAML3	viability	GTCATGGAATATGTCAACGGTGG	PRKCA	ENSG00000154229	-1.6611218361827	[43]	[41]	-8	hSpCas9	negative selection	12418812
66742685	66742708	17	+	28162770	OCIAML3	viability	GATGTGCAAGGAACACATGATGG	PRKCA	ENSG00000154229	-1.4496177309889882	[37]	[41]	-7	hSpCas9	negative selection	12418813
66688389	66688412	17	-	28162770	OCIAML3	viability	GCTCCGAAACTCCAAAGGAAAGG	PRKCA	ENSG00000154229	1.5843296009343493	[18]	[171]	9	hSpCas9	negative selection	12418814
66688427	66688450	17	-	28162770	OCIAML3	viability	GCGGCTTCCATACCATCCACTGG	PRKCA	ENSG00000154229	-0.23143756093945483	[69]	[179]	-2	hSpCas9	negative selection	12418815
66735488	66735511	17	+	28162770	OCIAML3	viability	GGTGATGCTTGCCGACAGGAAGG	PRKCA	ENSG00000154229	0.6589731008457078	[29]	[142]	6	hSpCas9	negative selection	12418816