Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 285368
• Symbol: PRRT3
• Description: proline rich transmembrane protein 3

DataSource: http://genomecrispr.dkfz.de/#!/results/PRRT3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
9946307	9946330	3	-	26627737	DLD1	viability	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	0.6842298857694462	[104]	[50,46,58]	6	hSpCas9	negative selection	823311
9946398	9946421	3	+	26627737	DLD1	viability	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.49345203424418316	[218]	[102,200,3]	5	hSpCas9	negative selection	823312
9946698	9946721	3	+	26627737	DLD1	viability	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	0.20070320585468904	[906]	[396,383,215]	2	hSpCas9	negative selection	823313
9946307	9946330	3	-	26627737	GBM cells	viability after 5 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	0.36730079875746324	[72]	[58,41]	5	hSpCas9	negative selection	905626
9946398	9946421	3	+	26627737	GBM cells	viability after 5 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.1722902249409386	[138]	[83,83]	2	hSpCas9	negative selection	905627
9946698	9946721	3	+	26627737	GBM cells	viability after 5 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	-0.4344271852747783	[348]	[104,171]	-6	hSpCas9	negative selection	905628
9946307	9946330	3	-	26627737	GBM cells	viability after 13 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	0.8451598700795089	[72]	[106,41]	8	hSpCas9	negative selection	987941
9946398	9946421	3	+	26627737	GBM cells	viability after 13 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.823857982542494	[138]	[170,102]	8	hSpCas9	negative selection	987942
9946698	9946721	3	+	26627737	GBM cells	viability after 13 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	-0.2846869444270348	[348]	[155,154]	-3	hSpCas9	negative selection	987943
9946307	9946330	3	-	26627737	GBM cells	viability after 21 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	0.056925244260706664	[72]	[46,35]	0	hSpCas9	negative selection	1070256
9946398	9946421	3	+	26627737	GBM cells	viability after 21 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.28555096878298847	[138]	[90,92]	3	hSpCas9	negative selection	1070257
9946698	9946721	3	+	26627737	GBM cells	viability after 21 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	-0.40944684540635384	[348]	[171,115]	-4	hSpCas9	negative selection	1070258
9946307	9946330	3	-	26627737	RPE1	viability after 9 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	2.3723900957290276	[93]	[123,188]	9	hSpCas9	negative selection	1152571
9946398	9946421	3	+	26627737	RPE1	viability after 9 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	1.6958323982747072	[288]	[255,340]	8	hSpCas9	negative selection	1152572
9946698	9946721	3	+	26627737	RPE1	viability after 9 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	0.8800489833898777	[626]	[493,189]	5	hSpCas9	negative selection	1152573
9946307	9946330	3	-	26627737	RPE1	viability after 12 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	2.3708492312650122	[93]	[83,179]	9	hSpCas9	negative selection	1234886
9946398	9946421	3	+	26627737	RPE1	viability after 12 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	1.4755006196828897	[288]	[161,272]	7	hSpCas9	negative selection	1234887
9946698	9946721	3	+	26627737	RPE1	viability after 12 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	0.38233630650426587	[626]	[238,198]	2	hSpCas9	negative selection	1234888
9946307	9946330	3	-	26627737	RPE1	viability after 15 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	2.269656872512975	[93]	[171,85]	9	hSpCas9	negative selection	1317201
9946398	9946421	3	+	26627737	RPE1	viability after 15 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	2.013501436147582	[288]	[212,442]	8	hSpCas9	negative selection	1317202
9946698	9946721	3	+	26627737	RPE1	viability after 15 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	0.7495812015235799	[626]	[342,254]	4	hSpCas9	negative selection	1317203
9946307	9946330	3	-	26627737	RPE1	viability after 18 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	2.7576025874635843	[93]	[143,200]	9	hSpCas9	negative selection	1399516
9946398	9946421	3	+	26627737	RPE1	viability after 18 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	2.298333381825958	[288]	[270,503]	9	hSpCas9	negative selection	1399517
9946698	9946721	3	+	26627737	RPE1	viability after 18 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	0.782527389505959	[626]	[321,257]	5	hSpCas9	negative selection	1399518
9946307	9946330	3	-	26627737	HeLa	viability after 8 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	1.8954299900588156	[47]	[148,24,74]	9	hSpCas9	negative selection	1481831
9946398	9946421	3	+	26627737	HeLa	viability after 8 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.8647908356832213	[193]	[182,254,37]	7	hSpCas9	negative selection	1481832
9946698	9946721	3	+	26627737	HeLa	viability after 8 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	1.3133938340414417	[277]	[247,336,304]	8	hSpCas9	negative selection	1481833
9946307	9946330	3	-	26627737	HeLa	viability after 12 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	2.0058025775291046	[47]	[117,42,82]	9	hSpCas9	negative selection	1564146
9946398	9946421	3	+	26627737	HeLa	viability after 12 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	1.494082690188959	[193]	[227,268,175]	8	hSpCas9	negative selection	1564147
9946698	9946721	3	+	26627737	HeLa	viability after 12 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	0.9316778403850616	[277]	[342,77,254]	7	hSpCas9	negative selection	1564148
9946307	9946330	3	-	26627737	HeLa	viability after 15 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	2.1981248839658174	[47]	[13,141,115]	9	hSpCas9	negative selection	1646461
9946398	9946421	3	+	26627737	HeLa	viability after 15 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	1.0737025194204184	[193]	[38,250,213]	7	hSpCas9	negative selection	1646462
9946698	9946721	3	+	26627737	HeLa	viability after 15 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	1.23469966714246	[277]	[281,223,294]	8	hSpCas9	negative selection	1646463
9946307	9946330	3	-	26627737	HeLa	viability after 18 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	2.1624751261504573	[47]	[3,118,115]	9	hSpCas9	negative selection	1728776
9946398	9946421	3	+	26627737	HeLa	viability after 18 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	1.102698896873712	[193]	[26,214,213]	7	hSpCas9	negative selection	1728777
9946698	9946721	3	+	26627737	HeLa	viability after 18 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	1.2639337845053236	[277]	[196,188,294]	8	hSpCas9	negative selection	1728778
9946307	9946330	3	-	26627737	HCT116	viability after 6 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	-1.1565363101863113	[74]	[3,5]	-6	hSpCas9	negative selection	1811091
9946398	9946421	3	+	26627737	HCT116	viability after 6 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	2.603020306040262	[432]	[196,532]	9	hSpCas9	negative selection	1811092
9946698	9946721	3	+	26627737	HCT116	viability after 6 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	-0.13992615090804816	[1299]	[247,150]	-1	hSpCas9	negative selection	1811093
9946307	9946330	3	-	26627737	HCT116	viability after 8 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	0.3905620785990904	[65]	[49,39,52]	4	hSpCas9	negative selection	1893406
9946398	9946421	3	+	26627737	HCT116	viability after 8 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.034908171685225586	[218]	[129,116,123]	0	hSpCas9	negative selection	1893407
9946698	9946721	3	+	26627737	HCT116	viability after 8 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	-1.0141853658203588	[766]	[191,106,326]	-8	hSpCas9	negative selection	1893408
9946307	9946330	3	-	26627737	HCT116	viability after 9 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	2.1185169180790657	[74]	[10,146]	9	hSpCas9	negative selection	1975721
9946398	9946421	3	+	26627737	HCT116	viability after 9 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	1.3586768088015715	[432]	[181,386]	8	hSpCas9	negative selection	1975722
9946698	9946721	3	+	26627737	HCT116	viability after 9 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	-0.4261657860535347	[1299]	[359,177]	-3	hSpCas9	negative selection	1975723
9946307	9946330	3	-	26627737	HCT116	viability after 12 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	0.19578346245177958	[65]	[38,70,9]	2	hSpCas9	negative selection	2058036
9946398	9946421	3	+	26627737	HCT116	viability after 12 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	-0.09950771837051248	[218]	[86,63,171]	-1	hSpCas9	negative selection	2058037
9946698	9946721	3	+	26627737	HCT116	viability after 12 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	-0.906396852117249	[766]	[183,178,283]	-7	hSpCas9	negative selection	2058038
9946307	9946330	3	-	26627737	HCT116	viability after 15 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	0.15601202445797213	[65]	[42,58,24]	1	hSpCas9	negative selection	2140351
9946398	9946421	3	+	26627737	HCT116	viability after 15 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.14992522976618633	[218]	[87,71,250]	1	hSpCas9	negative selection	2140352
9946698	9946721	3	+	26627737	HCT116	viability after 15 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	-0.7992015294037169	[766]	[215,212,324]	-7	hSpCas9	negative selection	2140353
9946307	9946330	3	-	26627737	HCT116	viability after 18 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	-1.0567345341081529	[65]	[12,24,6]	-7	hSpCas9	negative selection	2222666
9946398	9946421	3	+	26627737	HCT116	viability after 18 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.22666618361785393	[218]	[112,56,209]	2	hSpCas9	negative selection	2222667
9946698	9946721	3	+	26627737	HCT116	viability after 18 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	-1.4056425278119085	[766]	[108,125,187]	-8	hSpCas9	negative selection	2222668
9946582	9946605		-	24336571	A375	resistance to PLX after 7 days	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	0.021298116846476034	[9,7]	[8,9]	0	hSpCas9	positive selection	3138134
9946582	9946605		-	24336571	A375	resistance to PLX after 14 days	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.3796725170763443	[6,7]	[2,1]	-4	hSpCas9	positive selection	3195927
9946582	9946605		-	24336571	A375	viability after 7 days	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.2303386297489151	[11]	[9,7]	-3	hSpCas9	negative selection	3253720
9946582	9946605		-	24336571	A375	viability after 14 days	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.4407426396349749	[11]	[6,7]	-5	hSpCas9	negative selection	3311513
9946582	9946605	3	-	26780180	A375	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	1.99572759699257	[]	[]	9	hSpCas9	negative selection	3984884
9946787	9946810	3	-	26780180	A375	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.0195646949386327	[]	[]	0	hSpCas9	negative selection	3984885
9946582	9946605	3	-	26780180	HT29	viability (GeCKOv2 library)	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	1.28686057842454	[]	[]	6	hSpCas9	negative selection	4092850
9946787	9946810	3	-	26780180	HT29	viability (GeCKOv2 library)	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	1.0684140860933	[]	[]	5	hSpCas9	negative selection	4092851
9946582	9946605	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.12460946310168072	[3]	[2,0]	-3	hSpCas9	positive selection	4163337
9946582	9946605	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	1.444990124387129	[2]	[1,0,4,3]	9	hSpCas9	positive selection	4227359
9946582	9946605	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.41700728374646456	[3]	[1,1]	-7	hSpCas9	positive selection	4292521
9946787	9946810	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	-0.14420895990325522	[2]	[2,0]	-3	hSpCas9	positive selection	4292522
9946582	9946605	3	-	27260156	BXPC3	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.21333842659000657	[780]	[828,727,549,684]	-5	hSpCas9	negative selection	5564981
9946787	9946810	3	-	27260156	BXPC3	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.21244449615699468	[246]	[286,272,325,313]	5	hSpCas9	negative selection	5564982
9946582	9946605	3	-	27260156	A673	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.38739159315942556	[780]	[745,650,625,856]	-7	hSpCas9	negative selection	5686232
9946787	9946810	3	-	27260156	A673	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.36260104659280734	[246]	[371,369,437,340]	8	hSpCas9	negative selection	5686233
9946582	9946605	3	-	27260156	A375	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.20952794741853598	[780]	[726,813,940,685]	-3	hSpCas9	negative selection	5807483
9946787	9946810	3	-	27260156	A375	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.5832629438114552	[246]	[571,359,388,400]	8	hSpCas9	negative selection	5807484
9946582	9946605	3	-	27260156	COLO741	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.12088586766361242	[780]	[826,1005,910]	-3	hSpCas9	negative selection	5928734
9946787	9946810	3	-	27260156	COLO741	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.25897018148323947	[246]	[436,391,312]	5	hSpCas9	negative selection	5928735
9946582	9946605	3	-	27260156	CAL120	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.5144351179255677	[780]	[1046,368,679]	-6	hSpCas9	negative selection	6049985
9946787	9946810	3	-	27260156	CAL120	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.1790503049257195	[246]	[395,417,238]	2	hSpCas9	negative selection	6049986
9946582	9946605	3	-	27260156	CADOES1	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.6800040913246387	[780]	[606,352,422,428]	-8	hSpCas9	negative selection	6171236
9946787	9946810	3	-	27260156	CADOES1	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.3771988303035536	[246]	[331,235,307,317]	6	hSpCas9	negative selection	6171237
9946582	9946605	3	-	27260156	EWS502	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.3582271060390539	[780]	[489,636,820,652]	-6	hSpCas9	negative selection	6292487
9946787	9946810	3	-	27260156	EWS502	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.4024742333420329	[246]	[213,294,414,486]	7	hSpCas9	negative selection	6292488
9946582	9946605	3	-	27260156	EW8	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.6125509893946782	[780]	[440,496,313,422]	-8	hSpCas9	negative selection	6413738
9946787	9946810	3	-	27260156	EW8	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.537246231163554	[246]	[361,298,213,306]	8	hSpCas9	negative selection	6413739
9946582	9946605	3	-	27260156	CORL105	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.01811107494684372	[780]	[654,756,1277,973]	0	hSpCas9	negative selection	6534989
9946787	9946810	3	-	27260156	CORL105	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.5059602636274589	[246]	[411,300,509,436]	8	hSpCas9	negative selection	6534990
9946582	9946605	3	-	27260156	HS294T	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.501213956765982	[780]	[233,138,192,301]	-6	hSpCas9	negative selection	6656240
9946787	9946810	3	-	27260156	HS294T	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.3212830951761807	[246]	[60,187,92,141]	4	hSpCas9	negative selection	6656241
9946582	9946605	3	-	27260156	HCC44	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.5033751283108191	[780]	[646,633,691,529]	-6	hSpCas9	negative selection	6777491
9946787	9946810	3	-	27260156	HCC44	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.20999425375569536	[246]	[360,261,523,193]	3	hSpCas9	negative selection	6777492
9946582	9946605	3	-	27260156	G402	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.44828243542363294	[780]	[801,510,716,761]	-5	hSpCas9	negative selection	6898742
9946787	9946810	3	-	27260156	G402	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.4142956035308525	[246]	[349,496,330,423]	5	hSpCas9	negative selection	6898743
9946582	9946605	3	-	27260156	L33	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.3125215197616656	[780]	[514,296,362,699]	-6	hSpCas9	negative selection	7019993
9946787	9946810	3	-	27260156	L33	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	-0.26330698071916325	[246]	[223,51,186,174]	-6	hSpCas9	negative selection	7019994
9946582	9946605	3	-	27260156	K562	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.43292349323077595	[780]	[630,640,378,426]	-5	hSpCas9	negative selection	7141244
9946787	9946810	3	-	27260156	K562	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.789899474308735	[246]	[150,454,621,282]	8	hSpCas9	negative selection	7141245
9946582	9946605	3	-	27260156	HT29	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.2659851762890603	[780]	[690,902,747,809]	-5	hSpCas9	negative selection	7262495
9946787	9946810	3	-	27260156	HT29	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.3182940128196633	[246]	[361,481,355,310]	6	hSpCas9	negative selection	7262496
9946582	9946605	3	-	27260156	MHHES1	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	0.1455235314159281	[780]	[1534,923,901,647]	2	hSpCas9	negative selection	7383746
9946787	9946810	3	-	27260156	MHHES1	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.35982771505457756	[246]	[173,467,353,401]	6	hSpCas9	negative selection	7383747
9946582	9946605	3	-	27260156	MEWO	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.48443485837237643	[780]	[479,624,452]	-8	hSpCas9	negative selection	7504997
9946787	9946810	3	-	27260156	MEWO	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.7080971978116261	[246]	[529,169,462]	9	hSpCas9	negative selection	7504998
9946582	9946605	3	-	27260156	LNCAPCLONEFGC	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.5881377578187013	[780]	[506,433,437,499]	-7	hSpCas9	negative selection	7626248
9946787	9946810	3	-	27260156	LNCAPCLONEFGC	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.5910916801580148	[246]	[319,403,310,304]	8	hSpCas9	negative selection	7626249
9946582	9946605	3	-	27260156	PANC0327	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.16676706850461498	[780]	[689,534,806,456]	-2	hSpCas9	negative selection	7747499
9946787	9946810	3	-	27260156	PANC0327	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.8022174651133056	[246]	[307,638,280,262]	9	hSpCas9	negative selection	7747500
9946582	9946605	3	-	27260156	NCIH2009	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.21586209326181127	[780]	[1153,741,966]	-3	hSpCas9	negative selection	7868750
9946787	9946810	3	-	27260156	NCIH2009	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.5371521435627029	[246]	[701,403,436]	7	hSpCas9	negative selection	7868751
9946582	9946605	3	-	27260156	NCIH1373	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.13573354970530804	[780]	[1184,992,623,104]	-1	hSpCas9	negative selection	7990001
9946787	9946810	3	-	27260156	NCIH1373	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.473078375811516	[246]	[508,516,176,88]	4	hSpCas9	negative selection	7990002
9946582	9946605	3	-	27260156	PATU8902	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.6160378735407548	[780]	[792,822,629,592]	-5	hSpCas9	negative selection	8111252
9946787	9946810	3	-	27260156	PATU8902	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.7185896689182667	[246]	[586,130,666,884]	7	hSpCas9	negative selection	8111253
9946582	9946605	3	-	27260156	PANC1	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.4193108301962711	[780]	[638,512,553,321]	-6	hSpCas9	negative selection	8232503
9946787	9946810	3	-	27260156	PANC1	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.5283378433879298	[246]	[248,407,305,281]	8	hSpCas9	negative selection	8232504
9946582	9946605	3	-	27260156	PANC0813	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.08690538516082846	[780]	[1149,762,764,804]	-1	hSpCas9	negative selection	8353754
9946787	9946810	3	-	27260156	PANC0813	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.230713449912903	[246]	[385,424,199,352]	4	hSpCas9	negative selection	8353755
9946582	9946605	3	-	27260156	RDES	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.0796191491507604	[780]	[735,696,957,1057]	-1	hSpCas9	negative selection	8475005
9946787	9946810	3	-	27260156	RDES	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.42656736563355657	[246]	[321,309,467,448]	6	hSpCas9	negative selection	8475006
9946582	9946605	3	-	27260156	PC3	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.5148381979657748	[780]	[349,639,761,535]	-8	hSpCas9	negative selection	8596256
9946787	9946810	3	-	27260156	PC3	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.4174103749253444	[246]	[165,357,716,265]	8	hSpCas9	negative selection	8596257
9946582	9946605	3	-	27260156	PATU8988T	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.623136725968841	[780]	[433,346,759,393]	-7	hSpCas9	negative selection	8717507
9946787	9946810	3	-	27260156	PATU8988T	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	-0.763814821396192	[246]	[199,131,90,138]	-8	hSpCas9	negative selection	8717508
9946582	9946605	3	-	27260156	T47D	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.40078729099331034	[780]	[716,635,671,737]	-7	hSpCas9	negative selection	8838758
9946787	9946810	3	-	27260156	T47D	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.2864141112925739	[246]	[337,234,376,466]	6	hSpCas9	negative selection	8838759
9946582	9946605	3	-	27260156	SU8686	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.1621766919774651	[780]	[672,465,791,899]	-3	hSpCas9	negative selection	8960009
9946787	9946810	3	-	27260156	SU8686	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.10647674408436603	[246]	[303,207,277,265]	1	hSpCas9	negative selection	8960010
9946582	9946605	3	-	27260156	SKES1	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.39774265806016285	[780]	[511,680,552,610]	-7	hSpCas9	negative selection	9081260
9946787	9946810	3	-	27260156	SKES1	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.2579502788614084	[246]	[268,382,306,230]	5	hSpCas9	negative selection	9081261
9946582	9946605	3	-	27260156	TOV112D	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.22540084068670918	[780]	[412,1025,435,860]	-4	hSpCas9	negative selection	9202511
9946787	9946810	3	-	27260156	TOV112D	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.18391053939784974	[246]	[306,369,345,128]	3	hSpCas9	negative selection	9202512
9946582	9946605	3	-	27260156	TC71	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.2609096698227096	[780]	[681,743,779,578]	-6	hSpCas9	negative selection	9323762
9946787	9946810	3	-	27260156	TC71	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	-0.19983210593078748	[246]	[246,164,298,206]	-5	hSpCas9	negative selection	9323763
9946582	9946605	3	-	27260156	TC32	viability	AAAGCCGAGCTCGACGACGCTGG	PRRT3	ENSG00000163704	-0.5359524767925767	[780]	[584,239,648,645]	-8	hSpCas9	negative selection	9445013
9946787	9946810	3	-	27260156	TC32	viability	GTCCCGCAACGGTGTGGGACCGG	PRRT3	ENSG00000163704	0.32589579573680705	[246]	[189,236,446,335]	6	hSpCas9	negative selection	9445014
9946307	9946330	3	-	27869803	HPAFII	viability after 27 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	1.2201451645076524	[73]	[28,141,NaN]	8	hSpCas9	negative selection	9586382
9946398	9946421	3	+	27869803	HPAFII	viability after 27 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.7755773609306537	[159]	[137,148,NaN]	6	hSpCas9	negative selection	9586383
9946698	9946721	3	+	27869803	HPAFII	viability after 27 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	0.7428966621359905	[459]	[515,311,NaN]	6	hSpCas9	negative selection	9586384
9946307	9946330	3	-	27869803	HPAFII	viability after 15 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	0.298600725639127	[73]	[111,88,NaN]	3	hSpCas9	negative selection	9668831
9946398	9946421	3	+	27869803	HPAFII	viability after 15 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.4506796455493163	[159]	[345,165,NaN]	5	hSpCas9	negative selection	9668832
9946698	9946721	3	+	27869803	HPAFII	viability after 15 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	0.29719234592461574	[459]	[760,511,NaN]	3	hSpCas9	negative selection	9668833
9946307	9946330	3	-	27869803	ASPC1	viability after 36 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	1.36572683774855	[155]	[25,84,262]	9	hSpCas9	negative selection	9751280
9946398	9946421	3	+	27869803	ASPC1	viability after 36 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	-0.2608028342309301	[366]	[122,31,153]	-3	hSpCas9	negative selection	9751281
9946698	9946721	3	+	27869803	ASPC1	viability after 36 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	0.617424247467795	[1047]	[342,688,606]	6	hSpCas9	negative selection	9751282
9946307	9946330	3	-	27869803	PATU8988S	viability after 35 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	0.943271715765877	[99]	[52,101,NaN]	8	hSpCas9	negative selection	9833729
9946398	9946421	3	+	27869803	PATU8988S	viability after 35 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.8371403213026807	[436]	[282,345,NaN]	8	hSpCas9	negative selection	9833730
9946698	9946721	3	+	27869803	PATU8988S	viability after 35 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	-0.008341615969866822	[782]	[328,297,NaN]	0	hSpCas9	negative selection	9833731
9946307	9946330	3	-	27869803	PATU8988S	viability after 31 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	1.3673317968938434	[99]	[68,145,NaN]	9	hSpCas9	negative selection	9916178
9946398	9946421	3	+	27869803	PATU8988S	viability after 31 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.24415958853022596	[436]	[124,309,NaN]	3	hSpCas9	negative selection	9916179
9946698	9946721	3	+	27869803	PATU8988S	viability after 31 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	0.1766503489621719	[782]	[373,325,NaN]	2	hSpCas9	negative selection	9916180
9946307	9946330	3	-	27869803	HPAFII	viability after 35 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	1.6336607764478417	[73]	[16,227,NaN]	9	hSpCas9	negative selection	9998627
9946398	9946421	3	+	27869803	HPAFII	viability after 35 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	1.5064684406871751	[159]	[255,200,NaN]	8	hSpCas9	negative selection	9998628
9946698	9946721	3	+	27869803	HPAFII	viability after 35 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	0.43074700439168456	[459]	[343,279,NaN]	2	hSpCas9	negative selection	9998629
9946307	9946330	3	-	27869803	HPAFII	viability after 31 days	TGATTCTACCGCCGCTCGGCAGG	PRRT3	ENSG00000163704	1.503938595426171	[73]	[45,195,NaN]	9	hSpCas9	negative selection	10081076
9946398	9946421	3	+	27869803	HPAFII	viability after 31 days	TGATGACAGCCCGTGGCGCCAGG	PRRT3	ENSG00000163704	0.8138535552135182	[159]	[187,124,NaN]	6	hSpCas9	negative selection	10081077
9946698	9946721	3	+	27869803	HPAFII	viability after 31 days	TAGGTGCTCGCGGAAGAGCGCGG	PRRT3	ENSG00000163704	0.6916611561576649	[459]	[471,356,NaN]	5	hSpCas9	negative selection	10081078