Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 55159
• Symbol: RFWD3
• Description: ring finger and WD repeat domain 3

DataSource: http://genomecrispr.dkfz.de/#!/results/RFWD3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
74660970	74660993	16	-	26472758	Jiyoye	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-0.6839725065523219	[48]	[22]	-5	hSpCas9	negative selection	135982
74661136	74661159	16	-	26472758	Jiyoye	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-1.0289237333008001	[183]	[67]	-6	hSpCas9	negative selection	135983
74661376	74661399	16	-	26472758	Jiyoye	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	5.655102894949458	[0]	[37]	9	hSpCas9	negative selection	135984
74661326	74661349	16	+	26472758	Jiyoye	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	1.887801222412294	[42]	[119]	8	hSpCas9	negative selection	135985
74661197	74661220	16	-	26472758	Jiyoye	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	-0.3297902126603327	[349]	[209]	-2	hSpCas9	negative selection	135986
74644692	74644715	16	+	26472758	Jiyoye	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	0.0632209802885122	[329]	[259]	0	hSpCas9	negative selection	135987
74644633	74644656	16	-	26472758	Jiyoye	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	0.2851848571272629	[73]	[67]	2	hSpCas9	negative selection	135988
74636525	74636548	16	-	26472758	Jiyoye	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	0.17890639383275642	[40]	[34]	1	hSpCas9	negative selection	135989
74661431	74661454	16	-	26472758	Jiyoye	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	-0.04028359546534768	[104]	[76]	0	hSpCas9	negative selection	135990
74661224	74661247	16	+	26472758	Jiyoye	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	-0.7148151428727371	[73]	[33]	-5	hSpCas9	negative selection	135991
74660970	74660993	16	-	26472758	KBM7	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-1.5730256782723	[209,185]	[35,26]	-8	hSpCas9	negative selection	327100
74661136	74661159	16	-	26472758	KBM7	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-0.4646376877406979	[272,395]	[188,51]	-4	hSpCas9	negative selection	327101
74661376	74661399	16	-	26472758	KBM7	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	-0.3260454570977027	[216,179]	[90,58]	-3	hSpCas9	negative selection	327102
74661326	74661349	16	+	26472758	KBM7	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	-0.846207739864538	[453,408]	[125,100]	-6	hSpCas9	negative selection	327103
74661197	74661220	16	-	26472758	KBM7	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	0.09835481802406987	[1110,904]	[597,420]	1	hSpCas9	negative selection	327104
74644692	74644715	16	+	26472758	KBM7	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-0.6506954659620133	[1136,1138]	[379,308]	-5	hSpCas9	negative selection	327105
74644633	74644656	16	-	26472758	KBM7	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-1.9187619325302567	[358,593]	[31,86]	-8	hSpCas9	negative selection	327106
74636525	74636548	16	-	26472758	KBM7	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-1.638196534084136	[267,115]	[37,18]	-8	hSpCas9	negative selection	327107
74661431	74661454	16	-	26472758	KBM7	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	-0.0034038898710674337	[337,298]	[154,143]	0	hSpCas9	negative selection	327108
74661224	74661247	16	+	26472758	KBM7	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	-2.192579759794971	[158,147]	[9,20]	-8	hSpCas9	negative selection	327109
74660970	74660993	16	-	26472758	Raji	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	0.37041794120739313	[99]	[29]	3	hSpCas9	negative selection	518218
74661136	74661159	16	-	26472758	Raji	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	0.014937286609004397	[144]	[33]	0	hSpCas9	negative selection	518219
74661376	74661399	16	-	26472758	Raji	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	1.1562931358545456	[57]	[29]	8	hSpCas9	negative selection	518220
74661326	74661349	16	+	26472758	Raji	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	1.3593627526983976	[130]	[77]	9	hSpCas9	negative selection	518221
74661197	74661220	16	-	26472758	Raji	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	0.4799377033309298	[447]	[144]	4	hSpCas9	negative selection	518222
74644692	74644715	16	+	26472758	Raji	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	0.5697267494308002	[449]	[154]	5	hSpCas9	negative selection	518223
74644633	74644656	16	-	26472758	Raji	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-0.15248359138151113	[181]	[37]	-1	hSpCas9	negative selection	518224
74636525	74636548	16	-	26472758	Raji	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-0.8712428138338334	[133]	[16]	-6	hSpCas9	negative selection	518225
74661431	74661454	16	-	26472758	Raji	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.3117420338797859	[183]	[52]	3	hSpCas9	negative selection	518226
74661224	74661247	16	+	26472758	Raji	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	1.3379964635150157	[74]	[43]	9	hSpCas9	negative selection	518227
74660970	74660993	16	-	26472758	K562	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-1.244619353056174	[159]	[56]	-6	hSpCas9	negative selection	709336
74661136	74661159	16	-	26472758	K562	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	0.8011475476586589	[343]	[505]	6	hSpCas9	negative selection	709337
74661376	74661399	16	-	26472758	K562	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.5055435434916093	[125]	[150]	4	hSpCas9	negative selection	709338
74661326	74661349	16	+	26472758	K562	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	-0.020228529135647905	[357]	[297]	0	hSpCas9	negative selection	709339
74661197	74661220	16	-	26472758	K562	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	0.3459248477438719	[877]	[941]	2	hSpCas9	negative selection	709340
74644692	74644715	16	+	26472758	K562	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	0.2980947074489959	[1107]	[1149]	2	hSpCas9	negative selection	709341
74644633	74644656	16	-	26472758	K562	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	0.3100070692940236	[386]	[404]	2	hSpCas9	negative selection	709342
74636525	74636548	16	-	26472758	K562	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	0.17402939977504883	[146]	[139]	1	hSpCas9	negative selection	709343
74661431	74661454	16	-	26472758	K562	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	1.701419520048982	[215]	[592]	9	hSpCas9	negative selection	709344
74661224	74661247	16	+	26472758	K562	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	0.10181433222364644	[169]	[153]	0	hSpCas9	negative selection	709345
74632590	74632613	16	-	26627737	DLD1	viability	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-1.9302286585440285	[853]	[23,40,133]	-8	hSpCas9	negative selection	795359
74636484	74636507	16	-	26627737	DLD1	viability	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.6297014667334772	[300]	[161,145,130]	6	hSpCas9	negative selection	795360
74644375	74644398	16	-	26627737	DLD1	viability	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-1.0442853417258557	[752]	[112,71,149]	-7	hSpCas9	negative selection	795361
74644609	74644632	16	+	26627737	DLD1	viability	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-0.5799760635282127	[365]	[86,29,105]	-5	hSpCas9	negative selection	795362
74652083	74652106	16	-	26627737	DLD1	viability	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	-0.6482928299674021	[283]	[63,62,44]	-6	hSpCas9	negative selection	795363
74661307	74661330	16	-	26627737	DLD1	viability	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	-0.35414690716576436	[214]	[44,59,52]	-4	hSpCas9	negative selection	795364
74632590	74632613	16	-	26627737	GBM cells	viability after 5 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-0.5140251585091602	[457]	[178,164]	-7	hSpCas9	negative selection	877674
74636484	74636507	16	-	26627737	GBM cells	viability after 5 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	-0.26798343385905876	[118]	[65,39]	-4	hSpCas9	negative selection	877675
74644375	74644398	16	-	26627737	GBM cells	viability after 5 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-0.5110490674873118	[472]	[156,198]	-7	hSpCas9	negative selection	877676
74644609	74644632	16	+	26627737	GBM cells	viability after 5 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-0.9221159840689952	[105]	[26,32]	-8	hSpCas9	negative selection	877677
74652083	74652106	16	-	26627737	GBM cells	viability after 5 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	-0.17604818279553636	[157]	[70,78]	-3	hSpCas9	negative selection	877678
74661307	74661330	16	-	26627737	GBM cells	viability after 5 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.5907915795233536	[77]	[71,53]	8	hSpCas9	negative selection	877679
74632590	74632613	16	-	26627737	GBM cells	viability after 13 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-1.3475959795345487	[457]	[79,111]	-8	hSpCas9	negative selection	959989
74636484	74636507	16	-	26627737	GBM cells	viability after 13 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.2828517401043835	[118]	[77,78]	3	hSpCas9	negative selection	959990
74644375	74644398	16	-	26627737	GBM cells	viability after 13 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-1.0785188427250405	[472]	[131,112]	-8	hSpCas9	negative selection	959991
74644609	74644632	16	+	26627737	GBM cells	viability after 13 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.3268749595373064	[105]	[12,30]	-8	hSpCas9	negative selection	959992
74652083	74652106	16	-	26627737	GBM cells	viability after 13 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	0.09807424270476184	[157]	[88,93]	1	hSpCas9	negative selection	959993
74661307	74661330	16	-	26627737	GBM cells	viability after 13 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.7871066096427004	[77]	[61,81]	8	hSpCas9	negative selection	959994
74632590	74632613	16	-	26627737	GBM cells	viability after 21 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-1.659050203952218	[457]	[71,84]	-8	hSpCas9	negative selection	1042304
74636484	74636507	16	-	26627737	GBM cells	viability after 21 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.19984259882720135	[118]	[79,68]	2	hSpCas9	negative selection	1042305
74644375	74644398	16	-	26627737	GBM cells	viability after 21 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-1.3887917132752425	[472]	[94,100]	-8	hSpCas9	negative selection	1042306
74644609	74644632	16	+	26627737	GBM cells	viability after 21 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-3.525759060060178	[105]	[4,4]	-9	hSpCas9	negative selection	1042307
74652083	74652106	16	-	26627737	GBM cells	viability after 21 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	-0.18069092466528125	[157]	[81,69]	-2	hSpCas9	negative selection	1042308
74661307	74661330	16	-	26627737	GBM cells	viability after 21 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	1.1263858275639536	[77]	[103,81]	9	hSpCas9	negative selection	1042309
74632590	74632613	16	-	26627737	RPE1	viability after 9 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-0.6100055261644446	[1477]	[417,154]	-4	hSpCas9	negative selection	1124619
74636484	74636507	16	-	26627737	RPE1	viability after 9 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	-0.6548529740785094	[907]	[204,148]	-5	hSpCas9	negative selection	1124620
74644375	74644398	16	-	26627737	RPE1	viability after 9 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-1.3126264258929288	[1207]	[184,109]	-7	hSpCas9	negative selection	1124621
74644609	74644632	16	+	26627737	RPE1	viability after 9 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-2.06171116538463	[810]	[31,97]	-8	hSpCas9	negative selection	1124622
74652083	74652106	16	-	26627737	RPE1	viability after 9 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	-1.7793004938149446	[510]	[36,58]	-8	hSpCas9	negative selection	1124623
74661307	74661330	16	-	26627737	RPE1	viability after 9 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	-0.9805939796592475	[362]	[71,38]	-6	hSpCas9	negative selection	1124624
74632590	74632613	16	-	26627737	RPE1	viability after 12 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-1.7008934547573573	[1477]	[160,80]	-8	hSpCas9	negative selection	1206934
74636484	74636507	16	-	26627737	RPE1	viability after 12 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	-2.162630964249987	[907]	[53,54]	-8	hSpCas9	negative selection	1206935
74644375	74644398	16	-	26627737	RPE1	viability after 12 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-2.2475746703988024	[1207]	[96,37]	-8	hSpCas9	negative selection	1206936
74644609	74644632	16	+	26627737	RPE1	viability after 12 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-4.6679110189932205	[810]	[10,5]	-9	hSpCas9	negative selection	1206937
74652083	74652106	16	-	26627737	RPE1	viability after 12 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	-1.7905202022280573	[510]	[28,50]	-8	hSpCas9	negative selection	1206938
74661307	74661330	16	-	26627737	RPE1	viability after 12 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	-0.29924527094397657	[362]	[87,69]	-2	hSpCas9	negative selection	1206939
74632590	74632613	16	-	26627737	RPE1	viability after 15 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-1.5826715196936838	[1477]	[190,89]	-7	hSpCas9	negative selection	1289249
74636484	74636507	16	-	26627737	RPE1	viability after 15 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	-2.680344121300405	[907]	[7,70]	-9	hSpCas9	negative selection	1289250
74644375	74644398	16	-	26627737	RPE1	viability after 15 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-2.4919776897439716	[1207]	[46,73]	-8	hSpCas9	negative selection	1289251
74644609	74644632	16	+	26627737	RPE1	viability after 15 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-3.248168838552225	[810]	[15,31]	-9	hSpCas9	negative selection	1289252
74652083	74652106	16	-	26627737	RPE1	viability after 15 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	-3.6282219980322976	[510]	[0,21]	-9	hSpCas9	negative selection	1289253
74661307	74661330	16	-	26627737	RPE1	viability after 15 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	-0.8831982638188716	[362]	[45,64]	-5	hSpCas9	negative selection	1289254
74632590	74632613	16	-	26627737	RPE1	viability after 18 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-1.8569736466166895	[1477]	[156,59]	-8	hSpCas9	negative selection	1371564
74636484	74636507	16	-	26627737	RPE1	viability after 18 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	-3.489307297765127	[907]	[1,42]	-9	hSpCas9	negative selection	1371565
74644375	74644398	16	-	26627737	RPE1	viability after 18 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-2.1760601432299533	[1207]	[46,98]	-8	hSpCas9	negative selection	1371566
74644609	74644632	16	+	26627737	RPE1	viability after 18 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-4.909087583132944	[810]	[0,13]	-9	hSpCas9	negative selection	1371567
74652083	74652106	16	-	26627737	RPE1	viability after 18 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	-2.7893486152030085	[510]	[32,5]	-9	hSpCas9	negative selection	1371568
74661307	74661330	16	-	26627737	RPE1	viability after 18 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.26802194326620465	[362]	[145,87]	1	hSpCas9	negative selection	1371569
74632590	74632613	16	-	26627737	HeLa	viability after 8 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-0.9980792271062127	[657]	[207,73,160]	-7	hSpCas9	negative selection	1453879
74636484	74636507	16	-	26627737	HeLa	viability after 8 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.9838157697247315	[274]	[393,119,230]	7	hSpCas9	negative selection	1453880
74644375	74644398	16	-	26627737	HeLa	viability after 8 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-0.6037413554094924	[785]	[177,293,194]	-5	hSpCas9	negative selection	1453881
74644609	74644632	16	+	26627737	HeLa	viability after 8 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.1020306049716528	[364]	[149,33,55]	-8	hSpCas9	negative selection	1453882
74652083	74652106	16	-	26627737	HeLa	viability after 8 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	0.6190129384503382	[163]	[190,79,77]	5	hSpCas9	negative selection	1453883
74661307	74661330	16	-	26627737	HeLa	viability after 8 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	-0.6705109635101331	[389]	[131,94,98]	-6	hSpCas9	negative selection	1453884
74632590	74632613	16	-	26627737	HeLa	viability after 12 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	0.004080006895943344	[657]	[459,173,199]	0	hSpCas9	negative selection	1536194
74636484	74636507	16	-	26627737	HeLa	viability after 12 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	1.0216624271782062	[274]	[269,233,188]	7	hSpCas9	negative selection	1536195
74644375	74644398	16	-	26627737	HeLa	viability after 12 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-0.9436681518156875	[785]	[177,167,160]	-7	hSpCas9	negative selection	1536196
74644609	74644632	16	+	26627737	HeLa	viability after 12 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.6215702635204787	[364]	[0,26,119]	-9	hSpCas9	negative selection	1536197
74652083	74652106	16	-	26627737	HeLa	viability after 12 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	1.4809576413234395	[163]	[227,138,206]	8	hSpCas9	negative selection	1536198
74661307	74661330	16	-	26627737	HeLa	viability after 12 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	-1.253399551163774	[389]	[124,24,58]	-8	hSpCas9	negative selection	1536199
74632590	74632613	16	-	26627737	HeLa	viability after 15 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-1.816895689232045	[657]	[129,1,96]	-9	hSpCas9	negative selection	1618509
74636484	74636507	16	-	26627737	HeLa	viability after 15 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.9385625827935973	[274]	[138,226,283]	7	hSpCas9	negative selection	1618510
74644375	74644398	16	-	26627737	HeLa	viability after 15 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-1.8080708480597827	[785]	[43,87,146]	-9	hSpCas9	negative selection	1618511
74644609	74644632	16	+	26627737	HeLa	viability after 15 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.0711903093463455	[364]	[38,0,180]	-7	hSpCas9	negative selection	1618512
74652083	74652106	16	-	26627737	HeLa	viability after 15 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	0.5507999081770922	[163]	[87,77,129]	4	hSpCas9	negative selection	1618513
74661307	74661330	16	-	26627737	HeLa	viability after 15 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	-0.6416769916158719	[389]	[150,71,79]	-5	hSpCas9	negative selection	1618514
74632590	74632613	16	-	26627737	HeLa	viability after 18 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-1.7129450550657686	[657]	[97,1,96]	-9	hSpCas9	negative selection	1700824
74636484	74636507	16	-	26627737	HeLa	viability after 18 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.9446542408909856	[274]	[98,182,283]	7	hSpCas9	negative selection	1700825
74644375	74644398	16	-	26627737	HeLa	viability after 18 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-1.83275723794744	[785]	[27,70,146]	-9	hSpCas9	negative selection	1700826
74644609	74644632	16	+	26627737	HeLa	viability after 18 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.0820350870791087	[364]	[24,0,180]	-7	hSpCas9	negative selection	1700827
74652083	74652106	16	-	26627737	HeLa	viability after 18 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	0.5408010978744924	[163]	[54,67,129]	4	hSpCas9	negative selection	1700828
74661307	74661330	16	-	26627737	HeLa	viability after 18 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	-0.6549320870146762	[389]	[99,58,79]	-5	hSpCas9	negative selection	1700829
74632590	74632613	16	-	26627737	HCT116	viability after 6 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	1.2368833991429293	[1034]	[523,305]	6	hSpCas9	negative selection	1783139
74636484	74636507	16	-	26627737	HCT116	viability after 6 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	-0.7022440940159953	[877]	[147,49]	-4	hSpCas9	negative selection	1783140
74644375	74644398	16	-	26627737	HCT116	viability after 6 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	0.5965200144885147	[658]	[262,97]	3	hSpCas9	negative selection	1783141
74644609	74644632	16	+	26627737	HCT116	viability after 6 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-2.4894489465181984	[568]	[42,0]	-8	hSpCas9	negative selection	1783142
74652083	74652106	16	-	26627737	HCT116	viability after 6 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	-0.8571070715974338	[393]	[68,14]	-5	hSpCas9	negative selection	1783143
74661307	74661330	16	-	26627737	HCT116	viability after 6 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	-0.686202653357514	[407]	[64,25]	-4	hSpCas9	negative selection	1783144
74632590	74632613	16	-	26627737	HCT116	viability after 8 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	0.5095168844304304	[437]	[336,298,393]	5	hSpCas9	negative selection	1865454
74636484	74636507	16	-	26627737	HCT116	viability after 8 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.7382049776626776	[182]	[237,192,75]	7	hSpCas9	negative selection	1865455
74644375	74644398	16	-	26627737	HCT116	viability after 8 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	0.016848308333389517	[420]	[212,277,212]	0	hSpCas9	negative selection	1865456
74644609	74644632	16	+	26627737	HCT116	viability after 8 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.0838672935689915	[196]	[49,1,100]	-8	hSpCas9	negative selection	1865457
74652083	74652106	16	-	26627737	HCT116	viability after 8 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	0.2996178710552545	[132]	[64,101,102]	3	hSpCas9	negative selection	1865458
74661307	74661330	16	-	26627737	HCT116	viability after 8 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	1.0479953981695638	[87]	[71,104,122]	8	hSpCas9	negative selection	1865459
74632590	74632613	16	-	26627737	HCT116	viability after 9 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	0.8054541378025541	[1034]	[296,629]	6	hSpCas9	negative selection	1947769
74636484	74636507	16	-	26627737	HCT116	viability after 9 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	-0.3126339846729322	[877]	[252,137]	-2	hSpCas9	negative selection	1947770
74644375	74644398	16	-	26627737	HCT116	viability after 9 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	0.41260780346057735	[658]	[212,250]	3	hSpCas9	negative selection	1947771
74644609	74644632	16	+	26627737	HCT116	viability after 9 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-0.31474773664236144	[568]	[10,209]	-2	hSpCas9	negative selection	1947772
74652083	74652106	16	-	26627737	HCT116	viability after 9 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	1.1098299780088894	[393]	[464,38]	7	hSpCas9	negative selection	1947773
74661307	74661330	16	-	26627737	HCT116	viability after 9 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	-1.0682460899110127	[407]	[80,28]	-6	hSpCas9	negative selection	1947774
74632590	74632613	16	-	26627737	HCT116	viability after 12 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-0.23159249339323562	[437]	[276,153,148]	-2	hSpCas9	negative selection	2030084
74636484	74636507	16	-	26627737	HCT116	viability after 12 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.27094356115427026	[182]	[83,159,107]	2	hSpCas9	negative selection	2030085
74644375	74644398	16	-	26627737	HCT116	viability after 12 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-0.2765928583500107	[420]	[133,214,203]	-3	hSpCas9	negative selection	2030086
74644609	74644632	16	+	26627737	HCT116	viability after 12 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.319849712636935	[196]	[14,10,99]	-8	hSpCas9	negative selection	2030087
74652083	74652106	16	-	26627737	HCT116	viability after 12 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	0.3771047017216975	[132]	[56,119,98]	4	hSpCas9	negative selection	2030088
74661307	74661330	16	-	26627737	HCT116	viability after 12 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.7207039482963955	[87]	[103,67,53]	6	hSpCas9	negative selection	2030089
74632590	74632613	16	-	26627737	HCT116	viability after 15 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-0.025605936486033487	[437]	[316,114,316]	0	hSpCas9	negative selection	2112399
74636484	74636507	16	-	26627737	HCT116	viability after 15 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.5454029548648675	[182]	[60,242,144]	5	hSpCas9	negative selection	2112400
74644375	74644398	16	-	26627737	HCT116	viability after 15 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-0.3852758075043399	[420]	[223,227,108]	-4	hSpCas9	negative selection	2112401
74644609	74644632	16	+	26627737	HCT116	viability after 15 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.6935570183494224	[196]	[19,38,43]	-9	hSpCas9	negative selection	2112402
74652083	74652106	16	-	26627737	HCT116	viability after 15 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	-0.3567342740336903	[132]	[43,69,62]	-4	hSpCas9	negative selection	2112403
74661307	74661330	16	-	26627737	HCT116	viability after 15 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.6413660238781695	[87]	[104,82,51]	6	hSpCas9	negative selection	2112404
74632590	74632613	16	-	26627737	HCT116	viability after 18 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-0.7281375649546238	[437]	[81,167,130]	-6	hSpCas9	negative selection	2194714
74636484	74636507	16	-	26627737	HCT116	viability after 18 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.5507657228490028	[182]	[147,145,91]	4	hSpCas9	negative selection	2194715
74644375	74644398	16	-	26627737	HCT116	viability after 18 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-0.4112642245677954	[420]	[155,135,168]	-4	hSpCas9	negative selection	2194716
74644609	74644632	16	+	26627737	HCT116	viability after 18 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.4650559139671049	[196]	[3,16,85]	-8	hSpCas9	negative selection	2194717
74652083	74652106	16	-	26627737	HCT116	viability after 18 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	-1.0237300892637105	[132]	[16,27,50]	-7	hSpCas9	negative selection	2194718
74661307	74661330	16	-	26627737	HCT116	viability after 18 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.6283846902165076	[87]	[115,21,61]	5	hSpCas9	negative selection	2194719
74661276	74661299	16	+	24336569	HL60	viability	AGCAGGAGCTGGCTGGAGGATGG	RFWD3	ENSG00000168411	-0.28219152486915083	[357]	[622]	-2	hSpCas9	negative selection	2289345
74661307	74661330	16	-	24336569	HL60	viability	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.8503478701612488	[351]	[1342]	7	hSpCas9	negative selection	2289346
74661316	74661339	16	+	24336569	HL60	viability	CTGACCACATCAGCAGGAACAGG	RFWD3	ENSG00000168411	0.07839485722950212	[814]	[1820]	0	hSpCas9	negative selection	2289347
74661323	74661346	16	+	24336569	HL60	viability	CATCAGCAGGAACAGGCTGGAGG	RFWD3	ENSG00000168411	-0.47632371797010964	[993]	[1511]	-4	hSpCas9	negative selection	2289348
74661331	74661354	16	+	24336569	HL60	viability	GGAACAGGCTGGAGGAGGGCTGG	RFWD3	ENSG00000168411	-0.6910741264212502	[855]	[1121]	-6	hSpCas9	negative selection	2289349
74661357	74661380	16	-	24336569	HL60	viability	CTGGCATGGCCAGCAGCCAAGGG	RFWD3	ENSG00000168411	1.589913151909733	[26]	[171]	9	hSpCas9	negative selection	2289350
74661367	74661390	16	+	24336569	HL60	viability	CTGGCCATGCCAGCAGGAGCTGG	RFWD3	ENSG00000168411	-1.70595496553669	[36]	[23]	-9	hSpCas9	negative selection	2289351
74661376	74661399	16	-	24336569	HL60	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	-0.020959361669342425	[1073]	[2239]	0	hSpCas9	negative selection	2289352
74661416	74661439	16	-	24336569	HL60	viability	AGCAATGGAATATGATGTTCAGG	RFWD3	ENSG00000168411	-0.20486851665328865	[1170]	[2149]	-2	hSpCas9	negative selection	2289353
74661431	74661454	16	-	24336569	HL60	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	-1.4304858563985339	[1074]	[843]	-8	hSpCas9	negative selection	2289354
74661276	74661299	16	+	24336569	KBM7	viability	AGCAGGAGCTGGCTGGAGGATGG	RFWD3	ENSG00000168411	0.05668283025000753	[336]	[955]	0	hSpCas9	negative selection	2356522
74661307	74661330	16	-	24336569	KBM7	viability	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.55057945662695	[195]	[782]	5	hSpCas9	negative selection	2356523
74661316	74661339	16	+	24336569	KBM7	viability	CTGACCACATCAGCAGGAACAGG	RFWD3	ENSG00000168411	-0.38599993462952287	[1008]	[2105]	-3	hSpCas9	negative selection	2356524
74661323	74661346	16	+	24336569	KBM7	viability	CATCAGCAGGAACAGGCTGGAGG	RFWD3	ENSG00000168411	-1.0398181571303076	[645]	[856]	-6	hSpCas9	negative selection	2356525
74661331	74661354	16	+	24336569	KBM7	viability	GGAACAGGCTGGAGGAGGGCTGG	RFWD3	ENSG00000168411	-0.5458432128637485	[728]	[1361]	-4	hSpCas9	negative selection	2356526
74661357	74661380	16	-	24336569	KBM7	viability	CTGGCATGGCCAGCAGCCAAGGG	RFWD3	ENSG00000168411	0.3494807447808421	[220]	[767]	3	hSpCas9	negative selection	2356527
74661367	74661390	16	+	24336569	KBM7	viability	CTGGCCATGCCAGCAGGAGCTGG	RFWD3	ENSG00000168411	0.9786855581532152	[23]	[128]	8	hSpCas9	negative selection	2356528
74661376	74661399	16	-	24336569	KBM7	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.08231760344815942	[987]	[2852]	0	hSpCas9	negative selection	2356529
74661416	74661439	16	-	24336569	KBM7	viability	AGCAATGGAATATGATGTTCAGG	RFWD3	ENSG00000168411	-0.6471106600765185	[839]	[1462]	-5	hSpCas9	negative selection	2356530
74661431	74661454	16	-	24336569	KBM7	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.0030822124606825207	[764]	[2090]	0	hSpCas9	negative selection	2356531
74658840	74658863	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCCGCCTCCTAG	RFWD3	ENSG00000168411	-0.7325628323231226	[970,485]	[85,105]	-4	dCas9-VP64	positive selection	2435231
74653232	74653255	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGGCCAAGGTGGGAGGATGG	RFWD3	ENSG00000168411	1.4568039664330525	[0,1]	[0,0]	5	dCas9-VP64	positive selection	2436373
74657493	74657516	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGACGGAGTCTCGCTCTGCGG	RFWD3	ENSG00000168411	-0.9138531946650479	[176,89]	[14,14]	-5	dCas9-VP64	positive selection	2443887
74633014	74633037	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTCTGTAATCCCAGCACTTTGG	RFWD3	ENSG00000168411	0.6101179821993916	[242,252]	[22,147]	2	dCas9-VP64	positive selection	2461143
74645790	74645813	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCGCCCAGGCTGGAGTGTAGCGG	RFWD3	ENSG00000168411	1.1996159195397276	[69,17]	[36,4]	5	dCas9-VP64	positive selection	2463383
74630168	74630191	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCGCAACCTCCGCCTCCGAG	RFWD3	ENSG00000168411	-0.9705266312095737	[543,439]	[39,70]	-6	dCas9-VP64	positive selection	2469179
74653386	74653409	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGGATCACTTGAGCCCGAG	RFWD3	ENSG00000168411	1.3448043646809227	[134,24]	[56,28]	5	dCas9-VP64	positive selection	2469763
74642332	74642355	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCTGGTCTCAAACTCCTGAG	RFWD3	ENSG00000168411	1.754298476960665	[131,229]	[162,104]	6	dCas9-VP64	positive selection	2469922
74658840	74658863	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCCGCCTCCTAG	RFWD3	ENSG00000168411	0.3709996490739482	[598,467]	[394,67]	3	dCas9-VP64	positive selection	2530486
74653232	74653255	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGGCCAAGGTGGGAGGATGG	RFWD3	ENSG00000168411	-0.6172350415270842	[48,19]	[9,3]	-6	dCas9-VP64	positive selection	2531628
74657493	74657516	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGACGGAGTCTCGCTCTGCGG	RFWD3	ENSG00000168411	1.2938008933610645	[146,100]	[61,133]	7	dCas9-VP64	positive selection	2539142
74633014	74633037	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTCTGTAATCCCAGCACTTTGG	RFWD3	ENSG00000168411	-0.5842361043250603	[118,147]	[41,15]	-6	dCas9-VP64	positive selection	2556398
74645790	74645813	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCGCCCAGGCTGGAGTGTAGCGG	RFWD3	ENSG00000168411	2.7040346189546693	[41,50]	[11,181]	9	dCas9-VP64	positive selection	2558638
74630168	74630191	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCGCAACCTCCGCCTCCGAG	RFWD3	ENSG00000168411	0.25678800348412345	[582,649]	[296,187]	2	dCas9-VP64	positive selection	2564434
74653386	74653409	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGGATCACTTGAGCCCGAG	RFWD3	ENSG00000168411	0.9689409693551694	[107,845]	[92,495]	6	dCas9-VP64	positive selection	2565018
74642332	74642355	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCTGGTCTCAAACTCCTGAG	RFWD3	ENSG00000168411	0.3544513964898359	[322,573]	[129,237]	3	dCas9-VP64	positive selection	2565177
74661357	74661380	16	-	27260157	DLD1	viability	CTGGCATGGCCAGCAGCCAAGGG	RFWD3	ENSG00000168411	0.26722083582569	[]	[]	4	hSpCas9	negative selection	2574515
74644390	74644413	16	-	27260157	DLD1	viability	TGCCCGAACCCTGAGAGCTTTGG	RFWD3	ENSG00000168411	-0.21430509572312	[]	[]	-2	hSpCas9	negative selection	2579770
74644375	74644398	16	-	27260157	DLD1	viability	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-0.977461835552923	[]	[]	-7	hSpCas9	negative selection	2582185
74661323	74661346	16	+	27260157	DLD1	viability	CATCAGCAGGAACAGGCTGGAGG	RFWD3	ENSG00000168411	-0.715755193817715	[]	[]	-5	hSpCas9	negative selection	2584057
74661276	74661299	16	+	27260157	DLD1	viability	AGCAGGAGCTGGCTGGAGGATGG	RFWD3	ENSG00000168411	0.851220045392138	[]	[]	9	hSpCas9	negative selection	2584846
74661376	74661399	16	-	27260157	DLD1	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	-0.423515785794	[]	[]	-3	hSpCas9	negative selection	2605673
74637874	74637897	16	-	27260157	DLD1	viability	TCCTCACTGATAAGTGCACTAGG	RFWD3	ENSG00000168411	-1.43570425803591	[]	[]	-8	hSpCas9	negative selection	2606263
74661367	74661390	16	+	27260157	DLD1	viability	CTGGCCATGCCAGCAGGAGCTGG	RFWD3	ENSG00000168411	0.453804648494333	[]	[]	7	hSpCas9	negative selection	2608158
74644606	74644629	16	+	27260157	DLD1	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.414827602809938	[]	[]	-3	hSpCas9	negative selection	2608641
74661127	74661150	16	-	27260157	DLD1	viability	CAACATAGGCAGGGATCTGATGG	RFWD3	ENSG00000168411	-0.175286039296717	[]	[]	-1	hSpCas9	negative selection	2609969
74644396	74644419	16	+	27260157	DLD1	viability	CTCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	-0.0418351981332439	[]	[]	0	hSpCas9	negative selection	2610257
74649190	74649213	16	-	27260157	DLD1	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.0919888080014572	[]	[]	3	hSpCas9	negative selection	2612954
74661431	74661454	16	-	27260157	DLD1	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.352290130836265	[]	[]	4	hSpCas9	negative selection	2614518
74660999	74661022	16	+	27260157	DLD1	viability	TTCTCATTGGCCCTACACTGTGG	RFWD3	ENSG00000168411	-1.00611401846475	[]	[]	-7	hSpCas9	negative selection	2614633
74661047	74661070	16	-	27260157	DLD1	viability	GCAGAGACTTCATGGCATGCTGG	RFWD3	ENSG00000168411	1.3137947243245	[]	[]	9	hSpCas9	negative selection	2615094
74661416	74661439	16	-	27260157	DLD1	viability	AGCAATGGAATATGATGTTCAGG	RFWD3	ENSG00000168411	0.0838948847688772	[]	[]	3	hSpCas9	negative selection	2618374
74661307	74661330	16	-	27260157	DLD1	viability	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.303978093082445	[]	[]	4	hSpCas9	negative selection	2619510
74636460	74636483	16	+	27260157	DLD1	viability	AGTGGTACTTGTGCTTGTGCTGG	RFWD3	ENSG00000168411	-1.03846016905445	[]	[]	-7	hSpCas9	negative selection	2642556
74661331	74661354	16	+	27260157	DLD1	viability	GGAACAGGCTGGAGGAGGGCTGG	RFWD3	ENSG00000168411	-1.13779513361867	[]	[]	-7	hSpCas9	negative selection	2642891
74661316	74661339	16	+	27260157	DLD1	viability	CTGACCACATCAGCAGGAACAGG	RFWD3	ENSG00000168411	-0.528529965469382	[]	[]	-4	hSpCas9	negative selection	2644500
74661357	74661380	16	-	27260157	HT1080	viability	CTGGCATGGCCAGCAGCCAAGGG	RFWD3	ENSG00000168411	-0.244408305719147	[]	[]	0	hSpCas9	negative selection	2650645
74644390	74644413	16	-	27260157	HT1080	viability	TGCCCGAACCCTGAGAGCTTTGG	RFWD3	ENSG00000168411	-0.227351550732769	[]	[]	0	hSpCas9	negative selection	2655900
74644375	74644398	16	-	27260157	HT1080	viability	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-2.01101200313349	[]	[]	-9	hSpCas9	negative selection	2658315
74661323	74661346	16	+	27260157	HT1080	viability	CATCAGCAGGAACAGGCTGGAGG	RFWD3	ENSG00000168411	-0.759965575737602	[]	[]	-8	hSpCas9	negative selection	2660187
74661276	74661299	16	+	27260157	HT1080	viability	AGCAGGAGCTGGCTGGAGGATGG	RFWD3	ENSG00000168411	0.595938915113628	[]	[]	5	hSpCas9	negative selection	2660976
74661376	74661399	16	-	27260157	HT1080	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.0676564938076453	[]	[]	0	hSpCas9	negative selection	2681803
74637874	74637897	16	-	27260157	HT1080	viability	TCCTCACTGATAAGTGCACTAGG	RFWD3	ENSG00000168411	-1.73044054306282	[]	[]	-9	hSpCas9	negative selection	2682393
74661367	74661390	16	+	27260157	HT1080	viability	CTGGCCATGCCAGCAGGAGCTGG	RFWD3	ENSG00000168411	-0.735533340860451	[]	[]	-8	hSpCas9	negative selection	2684288
74644606	74644629	16	+	27260157	HT1080	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.89262735417465	[]	[]	-8	hSpCas9	negative selection	2684771
74661127	74661150	16	-	27260157	HT1080	viability	CAACATAGGCAGGGATCTGATGG	RFWD3	ENSG00000168411	-0.16450562618891	[]	[]	0	hSpCas9	negative selection	2686099
74644396	74644419	16	+	27260157	HT1080	viability	CTCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	-0.48055716284597	[]	[]	-7	hSpCas9	negative selection	2686387
74649190	74649213	16	-	27260157	HT1080	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.739082015167449	[]	[]	6	hSpCas9	negative selection	2689084
74661431	74661454	16	-	27260157	HT1080	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.45896344743005	[]	[]	4	hSpCas9	negative selection	2690648
74660999	74661022	16	+	27260157	HT1080	viability	TTCTCATTGGCCCTACACTGTGG	RFWD3	ENSG00000168411	-0.539380054702073	[]	[]	-7	hSpCas9	negative selection	2690763
74661047	74661070	16	-	27260157	HT1080	viability	GCAGAGACTTCATGGCATGCTGG	RFWD3	ENSG00000168411	1.92031379437073	[]	[]	9	hSpCas9	negative selection	2691224
74661416	74661439	16	-	27260157	HT1080	viability	AGCAATGGAATATGATGTTCAGG	RFWD3	ENSG00000168411	-0.585598222095062	[]	[]	-7	hSpCas9	negative selection	2694504
74661307	74661330	16	-	27260157	HT1080	viability	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.127230674487781	[]	[]	1	hSpCas9	negative selection	2695640
74636460	74636483	16	+	27260157	HT1080	viability	AGTGGTACTTGTGCTTGTGCTGG	RFWD3	ENSG00000168411	-2.5972394547502	[]	[]	-9	hSpCas9	negative selection	2718686
74661331	74661354	16	+	27260157	HT1080	viability	GGAACAGGCTGGAGGAGGGCTGG	RFWD3	ENSG00000168411	-0.438792885292985	[]	[]	-7	hSpCas9	negative selection	2719021
74661316	74661339	16	+	27260157	HT1080	viability	CTGACCACATCAGCAGGAACAGG	RFWD3	ENSG00000168411	0.336829111227505	[]	[]	3	hSpCas9	negative selection	2720630
74661357	74661380	16	-	27260157	MKN45	viability	CTGGCATGGCCAGCAGCCAAGGG	RFWD3	ENSG00000168411	0.48266671927429	[]	[]	6	hSpCas9	negative selection	2726775
74644390	74644413	16	-	27260157	MKN45	viability	TGCCCGAACCCTGAGAGCTTTGG	RFWD3	ENSG00000168411	-0.165630251215867	[]	[]	0	hSpCas9	negative selection	2732030
74644375	74644398	16	-	27260157	MKN45	viability	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-0.901945369043577	[]	[]	-7	hSpCas9	negative selection	2734445
74661323	74661346	16	+	27260157	MKN45	viability	CATCAGCAGGAACAGGCTGGAGG	RFWD3	ENSG00000168411	-0.53435183186156	[]	[]	-6	hSpCas9	negative selection	2736317
74661276	74661299	16	+	27260157	MKN45	viability	AGCAGGAGCTGGCTGGAGGATGG	RFWD3	ENSG00000168411	0.604575939303481	[]	[]	7	hSpCas9	negative selection	2737106
74661376	74661399	16	-	27260157	MKN45	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.488544939440441	[]	[]	6	hSpCas9	negative selection	2757933
74637874	74637897	16	-	27260157	MKN45	viability	TCCTCACTGATAAGTGCACTAGG	RFWD3	ENSG00000168411	-1.03205919351929	[]	[]	-8	hSpCas9	negative selection	2758523
74661367	74661390	16	+	27260157	MKN45	viability	CTGGCCATGCCAGCAGGAGCTGG	RFWD3	ENSG00000168411	0.583239416681573	[]	[]	7	hSpCas9	negative selection	2760418
74644606	74644629	16	+	27260157	MKN45	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.642068959679641	[]	[]	-7	hSpCas9	negative selection	2760901
74661127	74661150	16	-	27260157	MKN45	viability	CAACATAGGCAGGGATCTGATGG	RFWD3	ENSG00000168411	0.948351375699394	[]	[]	8	hSpCas9	negative selection	2762229
74644396	74644419	16	+	27260157	MKN45	viability	CTCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	-0.946148291022817	[]	[]	-7	hSpCas9	negative selection	2762517
74649190	74649213	16	-	27260157	MKN45	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	1.20380968777189	[]	[]	9	hSpCas9	negative selection	2765214
74661431	74661454	16	-	27260157	MKN45	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.308701641198085	[]	[]	5	hSpCas9	negative selection	2766778
74660999	74661022	16	+	27260157	MKN45	viability	TTCTCATTGGCCCTACACTGTGG	RFWD3	ENSG00000168411	-0.728967123595938	[]	[]	-7	hSpCas9	negative selection	2766893
74661047	74661070	16	-	27260157	MKN45	viability	GCAGAGACTTCATGGCATGCTGG	RFWD3	ENSG00000168411	0.257684979978684	[]	[]	5	hSpCas9	negative selection	2767354
74661416	74661439	16	-	27260157	MKN45	viability	AGCAATGGAATATGATGTTCAGG	RFWD3	ENSG00000168411	-0.974451061278856	[]	[]	-7	hSpCas9	negative selection	2770634
74661307	74661330	16	-	27260157	MKN45	viability	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	-0.116953554261217	[]	[]	0	hSpCas9	negative selection	2771770
74636460	74636483	16	+	27260157	MKN45	viability	AGTGGTACTTGTGCTTGTGCTGG	RFWD3	ENSG00000168411	-1.4280585021276	[]	[]	-8	hSpCas9	negative selection	2794816
74661331	74661354	16	+	27260157	MKN45	viability	GGAACAGGCTGGAGGAGGGCTGG	RFWD3	ENSG00000168411	0.0796543978131039	[]	[]	0	hSpCas9	negative selection	2795151
74661316	74661339	16	+	27260157	MKN45	viability	CTGACCACATCAGCAGGAACAGG	RFWD3	ENSG00000168411	-0.0659848469814772	[]	[]	0	hSpCas9	negative selection	2796760
74661357	74661380	16	-	27260157	RKO	viability	CTGGCATGGCCAGCAGCCAAGGG	RFWD3	ENSG00000168411	0.800098195106448	[]	[]	8	hSpCas9	negative selection	2802905
74644390	74644413	16	-	27260157	RKO	viability	TGCCCGAACCCTGAGAGCTTTGG	RFWD3	ENSG00000168411	0.324035735915216	[]	[]	1	hSpCas9	negative selection	2808160
74644375	74644398	16	-	27260157	RKO	viability	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-1.04781596169852	[]	[]	-8	hSpCas9	negative selection	2810575
74661323	74661346	16	+	27260157	RKO	viability	CATCAGCAGGAACAGGCTGGAGG	RFWD3	ENSG00000168411	-1.11048951968879	[]	[]	-8	hSpCas9	negative selection	2812447
74661276	74661299	16	+	27260157	RKO	viability	AGCAGGAGCTGGCTGGAGGATGG	RFWD3	ENSG00000168411	0.965536976495423	[]	[]	8	hSpCas9	negative selection	2813236
74661376	74661399	16	-	27260157	RKO	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.362133674455458	[]	[]	2	hSpCas9	negative selection	2834063
74637874	74637897	16	-	27260157	RKO	viability	TCCTCACTGATAAGTGCACTAGG	RFWD3	ENSG00000168411	-1.57230207444439	[]	[]	-9	hSpCas9	negative selection	2834653
74661367	74661390	16	+	27260157	RKO	viability	CTGGCCATGCCAGCAGGAGCTGG	RFWD3	ENSG00000168411	-0.637874141807676	[]	[]	-7	hSpCas9	negative selection	2836548
74644606	74644629	16	+	27260157	RKO	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-1.60135070126771	[]	[]	-9	hSpCas9	negative selection	2837031
74661127	74661150	16	-	27260157	RKO	viability	CAACATAGGCAGGGATCTGATGG	RFWD3	ENSG00000168411	-0.878468345143248	[]	[]	-8	hSpCas9	negative selection	2838359
74644396	74644419	16	+	27260157	RKO	viability	CTCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	-0.440165266331403	[]	[]	-6	hSpCas9	negative selection	2838647
74649190	74649213	16	-	27260157	RKO	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.111584185317736	[]	[]	0	hSpCas9	negative selection	2841344
74661431	74661454	16	-	27260157	RKO	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	-0.316505071984504	[]	[]	-6	hSpCas9	negative selection	2842908
74660999	74661022	16	+	27260157	RKO	viability	TTCTCATTGGCCCTACACTGTGG	RFWD3	ENSG00000168411	-0.336449317648245	[]	[]	-6	hSpCas9	negative selection	2843023
74661047	74661070	16	-	27260157	RKO	viability	GCAGAGACTTCATGGCATGCTGG	RFWD3	ENSG00000168411	0.960387436455849	[]	[]	8	hSpCas9	negative selection	2843484
74661416	74661439	16	-	27260157	RKO	viability	AGCAATGGAATATGATGTTCAGG	RFWD3	ENSG00000168411	-0.503804602515527	[]	[]	-6	hSpCas9	negative selection	2846764
74661307	74661330	16	-	27260157	RKO	viability	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	-0.442612411304228	[]	[]	-6	hSpCas9	negative selection	2847900
74636460	74636483	16	+	27260157	RKO	viability	AGTGGTACTTGTGCTTGTGCTGG	RFWD3	ENSG00000168411	-0.891810250298676	[]	[]	-8	hSpCas9	negative selection	2870946
74661331	74661354	16	+	27260157	RKO	viability	GGAACAGGCTGGAGGAGGGCTGG	RFWD3	ENSG00000168411	-1.43187160188709	[]	[]	-8	hSpCas9	negative selection	2871281
74661316	74661339	16	+	27260157	RKO	viability	CTGACCACATCAGCAGGAACAGG	RFWD3	ENSG00000168411	0.420224356328711	[]	[]	2	hSpCas9	negative selection	2872890
74661357	74661380	16	-	27260157	SF268	viability	CTGGCATGGCCAGCAGCCAAGGG	RFWD3	ENSG00000168411	0.391384972289597	[]	[]	4	hSpCas9	negative selection	2879035
74644390	74644413	16	-	27260157	SF268	viability	TGCCCGAACCCTGAGAGCTTTGG	RFWD3	ENSG00000168411	0.181857572501766	[]	[]	0	hSpCas9	negative selection	2884290
74644375	74644398	16	-	27260157	SF268	viability	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-0.712233579310481	[]	[]	-5	hSpCas9	negative selection	2886705
74661323	74661346	16	+	27260157	SF268	viability	CATCAGCAGGAACAGGCTGGAGG	RFWD3	ENSG00000168411	-0.62001763895013	[]	[]	-5	hSpCas9	negative selection	2888577
74661276	74661299	16	+	27260157	SF268	viability	AGCAGGAGCTGGCTGGAGGATGG	RFWD3	ENSG00000168411	0.68203153118193	[]	[]	8	hSpCas9	negative selection	2889366
74661376	74661399	16	-	27260157	SF268	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.687094042710458	[]	[]	8	hSpCas9	negative selection	2910193
74637874	74637897	16	-	27260157	SF268	viability	TCCTCACTGATAAGTGCACTAGG	RFWD3	ENSG00000168411	-0.329161345324595	[]	[]	-3	hSpCas9	negative selection	2910783
74661367	74661390	16	+	27260157	SF268	viability	CTGGCCATGCCAGCAGGAGCTGG	RFWD3	ENSG00000168411	-0.987770444095059	[]	[]	-7	hSpCas9	negative selection	2912678
74644606	74644629	16	+	27260157	SF268	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-1.03579771262485	[]	[]	-7	hSpCas9	negative selection	2913161
74661127	74661150	16	-	27260157	SF268	viability	CAACATAGGCAGGGATCTGATGG	RFWD3	ENSG00000168411	-0.263715688167772	[]	[]	-2	hSpCas9	negative selection	2914489
74644396	74644419	16	+	27260157	SF268	viability	CTCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	-1.59528875386776	[]	[]	-8	hSpCas9	negative selection	2914777
74649190	74649213	16	-	27260157	SF268	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.653671188041798	[]	[]	8	hSpCas9	negative selection	2917474
74661431	74661454	16	-	27260157	SF268	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.258745074768026	[]	[]	4	hSpCas9	negative selection	2919038
74660999	74661022	16	+	27260157	SF268	viability	TTCTCATTGGCCCTACACTGTGG	RFWD3	ENSG00000168411	-0.186982691909598	[]	[]	-1	hSpCas9	negative selection	2919153
74661047	74661070	16	-	27260157	SF268	viability	GCAGAGACTTCATGGCATGCTGG	RFWD3	ENSG00000168411	-0.0286620282919831	[]	[]	0	hSpCas9	negative selection	2919614
74661416	74661439	16	-	27260157	SF268	viability	AGCAATGGAATATGATGTTCAGG	RFWD3	ENSG00000168411	-0.332523410434206	[]	[]	-3	hSpCas9	negative selection	2922894
74661307	74661330	16	-	27260157	SF268	viability	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.358174903163073	[]	[]	4	hSpCas9	negative selection	2924030
74636460	74636483	16	+	27260157	SF268	viability	AGTGGTACTTGTGCTTGTGCTGG	RFWD3	ENSG00000168411	-1.23128158332418	[]	[]	-7	hSpCas9	negative selection	2947076
74661331	74661354	16	+	27260157	SF268	viability	GGAACAGGCTGGAGGAGGGCTGG	RFWD3	ENSG00000168411	-0.313714547240203	[]	[]	-2	hSpCas9	negative selection	2947411
74661316	74661339	16	+	27260157	SF268	viability	CTGACCACATCAGCAGGAACAGG	RFWD3	ENSG00000168411	-0.132340276413712	[]	[]	-1	hSpCas9	negative selection	2949020
74644693	74644716	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-0.5095621137901549	[3,3]	[2,0]	-6	hSpCas9	positive selection	3016474
74644571	74644594	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTATAGGTGCATTTCCACGTGG	RFWD3	ENSG00000168411	-0.48066852213868855	[2,3]	[3,0]	-6	hSpCas9	positive selection	3016475
74644557	74644580	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TACTTGTCCTTTAAGCCACGTGG	RFWD3	ENSG00000168411	-0.08530345289639096	[3,2]	[2,2]	-1	hSpCas9	positive selection	3016476
74661305	74661328	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGATGTGGTCAGCAGCCAGGGGG	RFWD3	ENSG00000168411	0.3559954970817272	[3,2]	[1,5]	7	hSpCas9	positive selection	3016477
74644693	74644716	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	0.04787011679419468	[3,3]	[1,2]	0	hSpCas9	positive selection	3084332
74644571	74644594	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTATAGGTGCATTTCCACGTGG	RFWD3	ENSG00000168411	0.1618170276088228	[2,2]	[3,0]	3	hSpCas9	positive selection	3084333
74644557	74644580	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TACTTGTCCTTTAAGCCACGTGG	RFWD3	ENSG00000168411	-1.0492615908165608	[3,3]	[0,0]	-9	hSpCas9	positive selection	3084334
74661305	74661328	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGATGTGGTCAGCAGCCAGGGGG	RFWD3	ENSG00000168411	-0.24941149866514478	[3,3]	[2,1]	-4	hSpCas9	positive selection	3084335
74652012	74652035		+	24336571	A375	resistance to PLX after 7 days	ACCTGCAACTCTTCAGATACAGG	RFWD3	ENSG00000168411	-0.11832465895183586	[30,33]	[28,29]	-4	hSpCas9	positive selection	3140610
74626519	74626542		-	24336571	A375	resistance to PLX after 7 days	CACCATACGAAGTGTGCTGATGG	RFWD3	ENSG00000168411	-0.30920541622618025	[15,17]	[12,13]	-8	hSpCas9	positive selection	3140611
74626491	74626514		-	24336571	A375	resistance to PLX after 7 days	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.046194798806411086	[16,13]	[11,17]	-1	hSpCas9	positive selection	3140612
74652012	74652035		+	24336571	A375	resistance to PLX after 14 days	ACCTGCAACTCTTCAGATACAGG	RFWD3	ENSG00000168411	-0.5803266652009591	[22,30]	[7,7]	-7	hSpCas9	positive selection	3198403
74626519	74626542		-	24336571	A375	resistance to PLX after 14 days	CACCATACGAAGTGTGCTGATGG	RFWD3	ENSG00000168411	-0.37948898161021033	[16,11]	[5,3]	-4	hSpCas9	positive selection	3198404
74626491	74626514		-	24336571	A375	resistance to PLX after 14 days	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.08293247828468184	[10,13]	[4,4]	-1	hSpCas9	positive selection	3198405
74652012	74652035		+	24336571	A375	viability after 7 days	ACCTGCAACTCTTCAGATACAGG	RFWD3	ENSG00000168411	0.17126184059804372	[29]	[30,33]	2	hSpCas9	negative selection	3256196
74626519	74626542		-	24336571	A375	viability after 7 days	CACCATACGAAGTGTGCTGATGG	RFWD3	ENSG00000168411	0.25102088640161024	[14]	[15,17]	4	hSpCas9	negative selection	3256197
74626491	74626514		-	24336571	A375	viability after 7 days	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	0.3941929711865185	[11]	[16,13]	6	hSpCas9	negative selection	3256198
74652012	74652035		+	24336571	A375	viability after 14 days	ACCTGCAACTCTTCAGATACAGG	RFWD3	ENSG00000168411	-0.04578174502372789	[29]	[22,30]	0	hSpCas9	negative selection	3313989
74626519	74626542		-	24336571	A375	viability after 14 days	CACCATACGAAGTGTGCTGATGG	RFWD3	ENSG00000168411	0.050467010915220295	[14]	[16,11]	0	hSpCas9	negative selection	3313990
74626491	74626514		-	24336571	A375	viability after 14 days	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	0.08371782706336708	[11]	[10,13]	1	hSpCas9	negative selection	3313991
74649190	74649213	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.03729453744579207	[156,156]	[0,0]	0	hSpCas9	positive selection	3389595
74644654	74644677	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.30312990105895976	[123,123]	[0,0]	1	hSpCas9	positive selection	3389596
74644606	74644629	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	0.6134700216711103	[99,99]	[0,0]	3	hSpCas9	positive selection	3389597
74644692	74644715	16	+	26780180	HT29	viability (Avana library 4 designs)	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	1.4399360618506	[]	[]	5	hSpCas9	negative selection	3454792
74644571	74644594	16	-	26780180	HT29	viability (Avana library 4 designs)	GGTATAGGTGCATTTCCACGTGG	RFWD3	ENSG00000168411	2.83476842675088	[]	[]	8	hSpCas9	negative selection	3454793
74644556	74644579	16	+	26780180	HT29	viability (Avana library 4 designs)	TACTTGTCCTTTAAGCCACGTGG	RFWD3	ENSG00000168411	1.90355601716064	[]	[]	7	hSpCas9	negative selection	3454794
74661305	74661328	16	-	26780180	HT29	viability (Avana library 4 designs)	TGATGTGGTCAGCAGCCAGGGGG	RFWD3	ENSG00000168411	1.30046665506986	[]	[]	5	hSpCas9	negative selection	3454795
74644571	74644594	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTATAGGTGCATTTCCACGTGG	RFWD3	ENSG00000168411	-3.02212556030443	[]	[]	-4	hSpCas9	negative selection	3552322
74644692	74644715	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-3.78717311485872	[]	[]	-4	hSpCas9	negative selection	3552323
74661305	74661328	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGATGTGGTCAGCAGCCAGGGGG	RFWD3	ENSG00000168411	5.59146182965281	[]	[]	8	hSpCas9	negative selection	3552324
74644556	74644579	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TACTTGTCCTTTAAGCCACGTGG	RFWD3	ENSG00000168411	0.832300998997755	[]	[]	1	hSpCas9	negative selection	3552325
74660987	74661010	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCAATGAGAACAAGAAGGAGGG	RFWD3	ENSG00000168411	-3.59608407215288	[]	[]	-4	hSpCas9	negative selection	3552326
74661136	74661159	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-3.05982765344949	[]	[]	-4	hSpCas9	negative selection	3552327
74644571	74644594	16	-	26780180	A375	viability (Avana lentiGuide)	GGTATAGGTGCATTTCCACGTGG	RFWD3	ENSG00000168411	6.1402651974092	[]	[]	5	hSpCas9	negative selection	3660981
74644692	74644715	16	+	26780180	A375	viability (Avana lentiGuide)	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	5.86274468859216	[]	[]	5	hSpCas9	negative selection	3660982
74661305	74661328	16	-	26780180	A375	viability (Avana lentiGuide)	TGATGTGGTCAGCAGCCAGGGGG	RFWD3	ENSG00000168411	-2.38183817000435	[]	[]	-4	hSpCas9	negative selection	3660983
74644556	74644579	16	+	26780180	A375	viability (Avana lentiGuide)	TACTTGTCCTTTAAGCCACGTGG	RFWD3	ENSG00000168411	-1.38719481000641	[]	[]	-2	hSpCas9	negative selection	3660984
74660987	74661010	16	-	26780180	A375	viability (Avana lentiGuide)	GCCAATGAGAACAAGAAGGAGGG	RFWD3	ENSG00000168411	-2.1896457864582	[]	[]	-4	hSpCas9	negative selection	3660985
74661136	74661159	16	-	26780180	A375	viability (Avana lentiGuide)	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	3.18836655356048	[]	[]	3	hSpCas9	negative selection	3660986
74644571	74644594	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTATAGGTGCATTTCCACGTGG	RFWD3	ENSG00000168411	-0.437012143045263	[4]	[3,2]	-6	hSpCas9	positive selection	3769588
74644692	74644715	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-0.375731442559502	[5]	[3,3]	-5	hSpCas9	positive selection	3769589
74661305	74661328	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATGTGGTCAGCAGCCAGGGGG	RFWD3	ENSG00000168411	0.3647898750155569	[4]	[4,5]	9	hSpCas9	positive selection	3769590
74644556	74644579	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TACTTGTCCTTTAAGCCACGTGG	RFWD3	ENSG00000168411	0.13894142602955598	[5]	[5,5]	3	hSpCas9	positive selection	3769591
74660987	74661010	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCAATGAGAACAAGAAGGAGGG	RFWD3	ENSG00000168411	-0.32024567000090204	[3]	[3,1]	-5	hSpCas9	positive selection	3769592
74661136	74661159	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-0.48705938961121403	[4]	[2,3]	-6	hSpCas9	positive selection	3769593
74644571	74644594	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTATAGGTGCATTTCCACGTGG	RFWD3	ENSG00000168411	-0.4113217993608917	[5]	[2,3]	-5	hSpCas9	positive selection	3878195
74644692	74644715	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-1.2538937672701103	[5]	[0,1]	-9	hSpCas9	positive selection	3878196
74661305	74661328	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATGTGGTCAGCAGCCAGGGGG	RFWD3	ENSG00000168411	-0.5393237414411639	[4]	[2,1]	-6	hSpCas9	positive selection	3878197
74644556	74644579	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TACTTGTCCTTTAAGCCACGTGG	RFWD3	ENSG00000168411	0.09552218911860866	[5]	[4,4]	2	hSpCas9	positive selection	3878198
74660987	74661010	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCAATGAGAACAAGAAGGAGGG	RFWD3	ENSG00000168411	0.26976696460112953	[4]	[4,5]	7	hSpCas9	positive selection	3878199
74661136	74661159	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-0.4615556620345317	[5]	[3,2]	-5	hSpCas9	positive selection	3878200
74652106	74652129	16	-	26780180	A375	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	1.4583191046913	[]	[]	8	hSpCas9	negative selection	3988576
74644606	74644629	16	+	26780180	A375	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	1.59662548483652	[]	[]	8	hSpCas9	negative selection	3988577
74649190	74649213	16	-	26780180	A375	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	1.06450693749156	[]	[]	5	hSpCas9	negative selection	3988578
74644654	74644677	16	-	26780180	A375	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	1.06322128223604	[]	[]	5	hSpCas9	negative selection	3988579
74626491	74626514	16	-	26780180	A375	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	1.72930783600812	[]	[]	9	hSpCas9	negative selection	3988580
74626517	74626540	16	+	26780180	A375	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.75167687959774	[]	[]	2	hSpCas9	negative selection	3988581
74652106	74652129	16	-	26780180	HT29	viability (GeCKOv2 library)	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	0.81538774874594	[]	[]	3	hSpCas9	negative selection	4096542
74644606	74644629	16	+	26780180	HT29	viability (GeCKOv2 library)	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	1.48064383826492	[]	[]	7	hSpCas9	negative selection	4096543
74649190	74649213	16	-	26780180	HT29	viability (GeCKOv2 library)	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	2.01060262597246	[]	[]	9	hSpCas9	negative selection	4096544
74644654	74644677	16	-	26780180	HT29	viability (GeCKOv2 library)	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	1.85118310221154	[]	[]	8	hSpCas9	negative selection	4096545
74626491	74626514	16	-	26780180	HT29	viability (GeCKOv2 library)	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	1.17351657140833	[]	[]	5	hSpCas9	negative selection	4096546
74626517	74626540	16	+	26780180	HT29	viability (GeCKOv2 library)	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	-0.369942743888537	[]	[]	-8	hSpCas9	negative selection	4096547
74652012	74652035	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCTGCAACTCTTCAGATACAGG	RFWD3	ENSG00000168411	0.01852726632171836	[4]	[3,2]	0	hSpCas9	positive selection	4166061
74626519	74626542	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACCATACGAAGTGTGCTGATGG	RFWD3	ENSG00000168411	0.12641378121957852	[3]	[2,2]	3	hSpCas9	positive selection	4166062
74626491	74626514	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	0.4020728766316457	[3]	[4,2]	8	hSpCas9	positive selection	4166063
74652012	74652035	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCTGCAACTCTTCAGATACAGG	RFWD3	ENSG00000168411	0.15433532437170117	[3]	[3,3,0,0]	1	hSpCas9	positive selection	4230083
74626519	74626542	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACCATACGAAGTGTGCTGATGG	RFWD3	ENSG00000168411	0.18016372809586434	[3]	[4,2,0,0]	1	hSpCas9	positive selection	4230084
74626491	74626514	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	0.7160660515943409	[3]	[1,2,0,3]	4	hSpCas9	positive selection	4230085
74626517	74626540	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.24592285066845332	[4]	[4,3]	5	hSpCas9	positive selection	4294590
74626491	74626514	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	0.05438632829290682	[3]	[3,2]	1	hSpCas9	positive selection	4294591
74652106	74652129	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.1503145028896396	[2]	[2,0]	-3	hSpCas9	positive selection	4294592
74649190	74649213	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.7241894897172595	[2]	[1,0]	-9	hSpCas9	positive selection	4358846
74644654	74644677	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	-0.4572835999970678	[2]	[1,0]	-7	hSpCas9	positive selection	4358847
74644606	74644629	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.4347774726288028	[2]	[1,0]	-7	hSpCas9	positive selection	4358848
74652106	74652128	16	-	27760321	OCIAML3	viability	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.7224298054655443	[376,300]	[157,161]	-6	hSpCas9	negative selection	4434216
74637874	74637896	16	+	27760321	OCIAML3	viability	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	-1.4100231067338074	[408,397]	[151,75]	-8	hSpCas9	negative selection	4434217
74644397	74644419	16	+	27760321	OCIAML3	viability	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	-2.5035995925390164	[350,318]	[43,48]	-9	hSpCas9	negative selection	4434218
74644610	74644632	16	+	27760321	OCIAML3	viability	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.2394648092667484	[474,414]	[107,197]	-8	hSpCas9	negative selection	4434219
74649151	74649173	16	-	27760321	OCIAML3	viability	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	-0.5828746995147882	[179,141]	[86,78]	-5	hSpCas9	negative selection	4434220
74652106	74652128	16	-	27760321	OCIAML2	viability	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.17850585480255748	[376,300]	[173,328]	-2	hSpCas9	negative selection	4517679
74637874	74637896	16	+	27760321	OCIAML2	viability	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	-1.1193350999324285	[408,397]	[128,178]	-8	hSpCas9	negative selection	4517680
74644397	74644419	16	+	27760321	OCIAML2	viability	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	-0.797415964350701	[350,318]	[138,177]	-7	hSpCas9	negative selection	4517681
74644610	74644632	16	+	27760321	OCIAML2	viability	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.3463336673686126	[474,414]	[123,163]	-8	hSpCas9	negative selection	4517682
74649151	74649173	16	-	27760321	OCIAML2	viability	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	-0.7839460343056253	[179,141]	[72,77]	-7	hSpCas9	negative selection	4517683
74652106	74652128	16	-	27760321	MV411	viability	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	0.693170452868348	[376,300]	[305,439]	5	hSpCas9	negative selection	4601142
74637874	74637896	16	+	27760321	MV411	viability	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	-0.6280068674800293	[408,397]	[254,48]	-4	hSpCas9	negative selection	4601143
74644397	74644419	16	+	27760321	MV411	viability	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	-0.42944505987639436	[350,318]	[221,76]	-3	hSpCas9	negative selection	4601144
74644610	74644632	16	+	27760321	MV411	viability	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-2.4409539085738903	[474,414]	[3,128]	-9	hSpCas9	negative selection	4601145
74649151	74649173	16	-	27760321	MV411	viability	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	-0.40453554476497144	[179,141]	[20,167]	-3	hSpCas9	negative selection	4601146
74652106	74652128	16	-	27760321	HL60	viability	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.12328093923998634	[376,300]	[243,261]	-1	hSpCas9	negative selection	4684605
74637874	74637896	16	+	27760321	HL60	viability	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	-1.7109602908505919	[408,397]	[80,121]	-9	hSpCas9	negative selection	4684606
74644397	74644419	16	+	27760321	HL60	viability	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	-1.1758783386004206	[350,318]	[105,136]	-8	hSpCas9	negative selection	4684607
74644610	74644632	16	+	27760321	HL60	viability	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-0.710146703101527	[474,414]	[161,284]	-6	hSpCas9	negative selection	4684608
74649151	74649173	16	-	27760321	HL60	viability	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	-1.0562064907993953	[179,141]	[40,85]	-8	hSpCas9	negative selection	4684609
74652106	74652128	16	-	27760321	HT1080	viability	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-3.6276670914869107	[300,234]	[0,16]	-7	hSpCas9	negative selection	4768068
74637874	74637896	16	+	27760321	HT1080	viability	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	-0.7410829595306222	[397,310]	[94,72]	-3	hSpCas9	negative selection	4768069
74644397	74644419	16	+	27760321	HT1080	viability	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	-0.7651858783690026	[318,248]	[67,64]	-3	hSpCas9	negative selection	4768070
74644610	74644632	16	+	27760321	HT1080	viability	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-2.6807062841911633	[414,323]	[0,46]	-7	hSpCas9	negative selection	4768071
74649151	74649173	16	-	27760321	HT1080	viability	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	1.2731526125652484	[141,110]	[180,56]	7	hSpCas9	negative selection	4768072
74652106	74652128	16	-	27760321	HT29	viability after 7 days	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	0.55473416947367	[300,234]	[696,502,349]	8	hSpCas9	negative selection	4851531
74637874	74637896	16	+	27760321	HT29	viability after 7 days	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	0.24711914184499478	[397,310]	[639,509,487]	4	hSpCas9	negative selection	4851532
74644397	74644419	16	+	27760321	HT29	viability after 7 days	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	0.03551378312306308	[318,248]	[456,302,373]	0	hSpCas9	negative selection	4851533
74644610	74644632	16	+	27760321	HT29	viability after 7 days	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-0.4778431468045706	[414,323]	[449,360,230]	-6	hSpCas9	negative selection	4851534
74649151	74649173	16	-	27760321	HT29	viability after 7 days	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	-1.0851569558667227	[141,110]	[76,109,43]	-8	hSpCas9	negative selection	4851535
74652106	74652128	16	-	27760321	HT29	viability after 25 days	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	0.6430880677143392	[300,234]	[662,449,289]	7	hSpCas9	negative selection	4934994
74637874	74637896	16	+	27760321	HT29	viability after 25 days	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	0.17560201324358582	[397,310]	[694,317,330]	1	hSpCas9	negative selection	4934995
74644397	74644419	16	+	27760321	HT29	viability after 25 days	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	0.072672987654464	[318,248]	[140,433,474]	0	hSpCas9	negative selection	4934996
74644610	74644632	16	+	27760321	HT29	viability after 25 days	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-0.24831783604068125	[414,323]	[383,334,343]	-3	hSpCas9	negative selection	4934997
74649151	74649173	16	-	27760321	HT29	viability after 25 days	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	0.34855425552118424	[141,110]	[273,116,151]	3	hSpCas9	negative selection	4934998
74652106	74652128	16	-	27760321	HT29	viability after 22 days	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	0.24041161429269	[300,234]	[471,376,244]	2	hSpCas9	negative selection	5018457
74637874	74637896	16	+	27760321	HT29	viability after 22 days	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	0.4999970577703482	[397,310]	[624,385,727]	5	hSpCas9	negative selection	5018458
74644397	74644419	16	+	27760321	HT29	viability after 22 days	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	0.1345565206830579	[318,248]	[340,354,385]	1	hSpCas9	negative selection	5018459
74644610	74644632	16	+	27760321	HT29	viability after 22 days	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-0.13223060382123686	[414,323]	[368,391,408]	-1	hSpCas9	negative selection	5018460
74649151	74649173	16	-	27760321	HT29	viability after 22 days	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	-0.31760255290164396	[141,110]	[69,96,186]	-3	hSpCas9	negative selection	5018461
74652106	74652128	16	-	27760321	HT29	viability after 19 days	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	0.37474575907280905	[300,234]	[393,623,181]	3	hSpCas9	negative selection	5101920
74637874	74637896	16	+	27760321	HT29	viability after 19 days	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	0.7400694448115323	[397,310]	[734,724,580]	7	hSpCas9	negative selection	5101921
74644397	74644419	16	+	27760321	HT29	viability after 19 days	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	-0.2832303787298537	[318,248]	[474,151,197]	-3	hSpCas9	negative selection	5101922
74644610	74644632	16	+	27760321	HT29	viability after 19 days	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	0.4697713401889947	[414,323]	[474,902,373]	4	hSpCas9	negative selection	5101923
74649151	74649173	16	-	27760321	HT29	viability after 19 days	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	0.9293806332445648	[141,110]	[90,87,614]	8	hSpCas9	negative selection	5101924
74652106	74652128	16	-	27760321	HT29	viability after 16 days	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	0.5439786260209808	[300,234]	[430,316,565]	6	hSpCas9	negative selection	5185383
74637874	74637896	16	+	27760321	HT29	viability after 16 days	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	0.25982576884066566	[397,310]	[598,336,503]	3	hSpCas9	negative selection	5185384
74644397	74644419	16	+	27760321	HT29	viability after 16 days	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	0.24438456270411532	[318,248]	[250,386,478]	2	hSpCas9	negative selection	5185385
74644610	74644632	16	+	27760321	HT29	viability after 16 days	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	0.09469733647929646	[414,323]	[476,312,540]	1	hSpCas9	negative selection	5185386
74649151	74649173	16	-	27760321	HT29	viability after 16 days	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	-1.0567211077432521	[141,110]	[128,24,56]	-7	hSpCas9	negative selection	5185387
74652106	74652128	16	-	27760321	HT29	viability after 13 days	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	0.41922205383225053	[300,234]	[749,192,309]	5	hSpCas9	negative selection	5268846
74637874	74637896	16	+	27760321	HT29	viability after 13 days	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	0.3254183173942125	[397,310]	[538,475,529]	4	hSpCas9	negative selection	5268847
74644397	74644419	16	+	27760321	HT29	viability after 13 days	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	0.402054058539507	[318,248]	[369,429,501]	5	hSpCas9	negative selection	5268848
74644610	74644632	16	+	27760321	HT29	viability after 13 days	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-0.23004189811607645	[414,323]	[380,411,306]	-3	hSpCas9	negative selection	5268849
74649151	74649173	16	-	27760321	HT29	viability after 13 days	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	-1.0173870964770604	[141,110]	[111,42,62]	-7	hSpCas9	negative selection	5268850
74652106	74652128	16	-	27760321	HT29	viability after 10 days	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	0.09088702268026516	[300,234]	[339,281,442]	1	hSpCas9	negative selection	5352309
74637874	74637896	16	+	27760321	HT29	viability after 10 days	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	0.5778286085930676	[397,310]	[890,457,627]	7	hSpCas9	negative selection	5352310
74644397	74644419	16	+	27760321	HT29	viability after 10 days	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	0.5628552000960256	[318,248]	[531,593,448]	7	hSpCas9	negative selection	5352311
74644610	74644632	16	+	27760321	HT29	viability after 10 days	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-0.20489501433488844	[414,323]	[354,545,305]	-3	hSpCas9	negative selection	5352312
74649151	74649173	16	-	27760321	HT29	viability after 10 days	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	-1.004896529644847	[141,110]	[36,114,84]	-8	hSpCas9	negative selection	5352313
74652106	74652128	16	-	27760321	MOLM13	viability	CATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.6275520912437198	[376,300]	[101,140]	-4	hSpCas9	negative selection	5435772
74637874	74637896	16	+	27760321	MOLM13	viability	CCTAGTGCACTTATCAGTGAGG	RFWD3	ENSG00000168411	-0.2772497827542021	[408,397]	[130,236]	-2	hSpCas9	negative selection	5435773
74644397	74644419	16	+	27760321	MOLM13	viability	TCTCAGGGTTCGGGCATAAAGG	RFWD3	ENSG00000168411	-0.4517685767920472	[350,318]	[129,144]	-3	hSpCas9	negative selection	5435774
74644610	74644632	16	+	27760321	MOLM13	viability	GCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-0.6903296960173213	[474,414]	[225,94]	-4	hSpCas9	negative selection	5435775
74649151	74649173	16	-	27760321	MOLM13	viability	AAGTTACATGTATCGATGGAGG	RFWD3	ENSG00000168411	0.06399685039452696	[179,141]	[203,0]	0	hSpCas9	negative selection	5435776
74666445	74666468	16	+	27661255	K562	viability	GCCCGAGGCTAGGCTCTCGGGGG	RFWD3	ENSG00000168411	0.05482934752451207	[156,215]	[202,111]	1	dCas9-KRAB	negative selection	5507048
74666599	74666622	16	+	27661255	K562	viability	GGCTCCTTAGCCCCGACCACTGG	RFWD3	ENSG00000168411	-0.0705025516862744	[578,491]	[434,385]	-3	dCas9-KRAB	negative selection	5507049
74666819	74666842	16	-	27661255	K562	viability	GTAACTACCGAGTCTTCGGCGGG	RFWD3	ENSG00000168411	-0.3243919450876546	[964,1075]	[686,617]	-7	dCas9-KRAB	negative selection	5507050
74666847	74666870	16	-	27661255	K562	viability	GCGTAGGTGCATTCGGAGTGCGG	RFWD3	ENSG00000168411	-0.2524071182295709	[623,599]	[468,360]	-6	dCas9-KRAB	negative selection	5507051
74666854	74666877	16	-	27661255	K562	viability	GCAGTTGGCGTAGGTGCATTCGG	RFWD3	ENSG00000168411	-0.18352635760846425	[211,185]	[142,137]	-5	dCas9-KRAB	negative selection	5507052
74626517	74626540	16	+	27260156	BXPC3	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.18418082145888115	[1407]	[1522,1573,1866,1749]	4	hSpCas9	negative selection	5567050
74626491	74626514	16	-	27260156	BXPC3	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.05425946146446203	[722]	[620,709,757,845]	-1	hSpCas9	negative selection	5567051
74652106	74652129	16	-	27260156	BXPC3	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.10322664340323368	[356]	[311,349,372,357]	-2	hSpCas9	negative selection	5567052
74649190	74649213	16	-	27260156	BXPC3	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.21296318190679617	[393]	[507,396,384,635]	5	hSpCas9	negative selection	5631306
74644654	74644677	16	-	27260156	BXPC3	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.2094537362259674	[249]	[310,209,322,376]	4	hSpCas9	negative selection	5631307
74644606	74644629	16	+	27260156	BXPC3	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.4155796583690152	[325]	[240,218,326,235]	-7	hSpCas9	negative selection	5631308
74626517	74626540	16	+	27260156	A673	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.08411949942573904	[1407]	[1936,1573,1686,2001]	2	hSpCas9	negative selection	5688301
74626491	74626514	16	-	27260156	A673	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.22381587499163846	[722]	[898,631,661,803]	-5	hSpCas9	negative selection	5688302
74652106	74652129	16	-	27260156	A673	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.4861518539746615	[356]	[368,282,195,388]	-8	hSpCas9	negative selection	5688303
74649190	74649213	16	-	27260156	A673	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.12891435108707877	[393]	[466,438,363,465]	-3	hSpCas9	negative selection	5752557
74644654	74644677	16	-	27260156	A673	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	-0.14367510801548866	[249]	[289,311,227,256]	-4	hSpCas9	negative selection	5752558
74644606	74644629	16	+	27260156	A673	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.9460819488289207	[325]	[253,145,223,194]	-9	hSpCas9	negative selection	5752559
74626517	74626540	16	+	27260156	A375	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	-0.11659056497777076	[1407]	[1571,1713,1412,1403]	-2	hSpCas9	negative selection	5809552
74626491	74626514	16	-	27260156	A375	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.3905696029757855	[722]	[681,883,574,485]	-5	hSpCas9	negative selection	5809553
74652106	74652129	16	-	27260156	A375	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.4736459573414226	[356]	[230,415,364,213]	-6	hSpCas9	negative selection	5809554
74649190	74649213	16	-	27260156	A375	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.0052769322650132455	[393]	[388,443,429,554]	0	hSpCas9	negative selection	5873808
74644654	74644677	16	-	27260156	A375	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	-0.03086274545808121	[249]	[448,220,156,304]	0	hSpCas9	negative selection	5873809
74644606	74644629	16	+	27260156	A375	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-1.454948929518106	[325]	[113,70,263,100]	-9	hSpCas9	negative selection	5873810
74626517	74626540	16	+	27260156	COLO741	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.21398995658458042	[1407]	[1956,2206,2080]	4	hSpCas9	negative selection	5930803
74626491	74626514	16	-	27260156	COLO741	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	0.05038528369126527	[722]	[1048,878,947]	1	hSpCas9	negative selection	5930804
74652106	74652129	16	-	27260156	COLO741	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.07822554886698047	[356]	[424,344,517]	-2	hSpCas9	negative selection	5930805
74649190	74649213	16	-	27260156	COLO741	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.20521809383275458	[393]	[500,357,453]	-4	hSpCas9	negative selection	5995059
74644654	74644677	16	-	27260156	COLO741	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.24054997610180717	[249]	[215,552,350]	5	hSpCas9	negative selection	5995060
74644606	74644629	16	+	27260156	COLO741	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.601287657347213	[325]	[207,340,268]	-8	hSpCas9	negative selection	5995061
74626517	74626540	16	+	27260156	CAL120	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.48103428792859493	[1407]	[3014,1730,2670]	7	hSpCas9	negative selection	6052054
74626491	74626514	16	-	27260156	CAL120	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	0.06374733379927766	[722]	[1418,832,645]	1	hSpCas9	negative selection	6052055
74652106	74652129	16	-	27260156	CAL120	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.5896167000854371	[356]	[213,291,365]	-7	hSpCas9	negative selection	6052056
74649190	74649213	16	-	27260156	CAL120	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.04443565326377974	[393]	[504,309,612]	0	hSpCas9	negative selection	6116310
74644654	74644677	16	-	27260156	CAL120	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.0269746977758637	[249]	[260,176,500]	0	hSpCas9	negative selection	6116311
74644606	74644629	16	+	27260156	CAL120	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.30248768172770313	[325]	[510,225,277]	-4	hSpCas9	negative selection	6116312
74626517	74626540	16	+	27260156	CADOES1	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.2660139032018878	[1407]	[1330,1624,1650,1696]	4	hSpCas9	negative selection	6173305
74626491	74626514	16	-	27260156	CADOES1	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.31257877215614327	[722]	[453,608,564,537]	-5	hSpCas9	negative selection	6173306
74652106	74652129	16	-	27260156	CADOES1	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.2683070940073227	[356]	[330,187,266,317]	-4	hSpCas9	negative selection	6173307
74649190	74649213	16	-	27260156	CADOES1	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.3832790084893588	[393]	[366,258,255,239]	-6	hSpCas9	negative selection	6237561
74644654	74644677	16	-	27260156	CADOES1	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	-0.13240364762300005	[249]	[238,228,205,172]	-2	hSpCas9	negative selection	6237562
74644606	74644629	16	+	27260156	CADOES1	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.8537304331639588	[325]	[216,110,145,197]	-9	hSpCas9	negative selection	6237563
74626517	74626540	16	+	27260156	EWS502	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.34068765208409624	[1407]	[1415,2483,1766,1912]	6	hSpCas9	negative selection	6294556
74626491	74626514	16	-	27260156	EWS502	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.5316350658467753	[722]	[418,609,514,586]	-7	hSpCas9	negative selection	6294557
74652106	74652129	16	-	27260156	EWS502	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.9150866989731377	[356]	[194,162,247,197]	-8	hSpCas9	negative selection	6294558
74649190	74649213	16	-	27260156	EWS502	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.441468963710974	[393]	[339,305,311,262]	-6	hSpCas9	negative selection	6358812
74644654	74644677	16	-	27260156	EWS502	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.16280809414638997	[249]	[350,231,230,370]	3	hSpCas9	negative selection	6358813
74644606	74644629	16	+	27260156	EWS502	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.9846817748793288	[325]	[129,222,151,196]	-8	hSpCas9	negative selection	6358814
74626517	74626540	16	+	27260156	EW8	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.2774445991306347	[1407]	[1652,1270,1218,1441]	5	hSpCas9	negative selection	6415807
74626491	74626514	16	-	27260156	EW8	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.3969954273427604	[722]	[716,295,487,299]	-6	hSpCas9	negative selection	6415808
74652106	74652129	16	-	27260156	EW8	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.23975494557673643	[356]	[386,214,203,195]	-4	hSpCas9	negative selection	6415809
74649190	74649213	16	-	27260156	EW8	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.051191446781994165	[393]	[508,179,214,364]	-1	hSpCas9	negative selection	6480063
74644654	74644677	16	-	27260156	EW8	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.2963082943115254	[249]	[273,191,169,373]	5	hSpCas9	negative selection	6480064
74644606	74644629	16	+	27260156	EW8	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.9809032929685404	[325]	[176,169,74,127]	-9	hSpCas9	negative selection	6480065
74626517	74626540	16	+	27260156	CORL105	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	-0.16242277045025455	[1407]	[1418,1495,1720,1291]	-3	hSpCas9	negative selection	6537058
74626491	74626514	16	-	27260156	CORL105	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.24133072911741316	[722]	[578,822,1003,496]	-4	hSpCas9	negative selection	6537059
74652106	74652129	16	-	27260156	CORL105	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.6178831442995774	[356]	[297,252,343,206]	-8	hSpCas9	negative selection	6537060
74649190	74649213	16	-	27260156	CORL105	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.22260547925208718	[393]	[415,407,559,223]	-4	hSpCas9	negative selection	6601314
74644654	74644677	16	-	27260156	CORL105	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.2572209318551423	[249]	[443,288,345,323]	5	hSpCas9	negative selection	6601315
74644606	74644629	16	+	27260156	CORL105	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-1.1021770434309055	[325]	[256,117,108,219]	-9	hSpCas9	negative selection	6601316
74626517	74626540	16	+	27260156	HS294T	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.11599879987400352	[1407]	[512,559,555,766]	1	hSpCas9	negative selection	6658309
74626491	74626514	16	-	27260156	HS294T	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.21838084466903313	[722]	[172,360,216,205]	-3	hSpCas9	negative selection	6658310
74652106	74652129	16	-	27260156	HS294T	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.32103409257691634	[356]	[90,93,128,133]	-4	hSpCas9	negative selection	6658311
74649190	74649213	16	-	27260156	HS294T	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.29646874124199096	[393]	[147,130,90,122]	-4	hSpCas9	negative selection	6722565
74644654	74644677	16	-	27260156	HS294T	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.6913952351296327	[249]	[61,117,104,387]	8	hSpCas9	negative selection	6722566
74644606	74644629	16	+	27260156	HS294T	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.3009087172107904	[325]	[68,134,114,89]	-4	hSpCas9	negative selection	6722567
74626517	74626540	16	+	27260156	HCC44	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.2146224241044299	[1407]	[1903,1639,2231,1705]	3	hSpCas9	negative selection	6779560
74626491	74626514	16	-	27260156	HCC44	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.2617909585005274	[722]	[816,538,696,703]	-4	hSpCas9	negative selection	6779561
74652106	74652129	16	-	27260156	HCC44	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.15963929373219193	[356]	[277,341,456,376]	-3	hSpCas9	negative selection	6779562
74649190	74649213	16	-	27260156	HCC44	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.002453852722189176	[393]	[513,326,596,388]	0	hSpCas9	negative selection	6843816
74644654	74644677	16	-	27260156	HCC44	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.4931522886615922	[249]	[412,353,356,462]	7	hSpCas9	negative selection	6843817
74644606	74644629	16	+	27260156	HCC44	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.6791188483376618	[325]	[225,220,316,172]	-7	hSpCas9	negative selection	6843818
74626517	74626540	16	+	27260156	G402	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.1939107394936621	[1407]	[1959,2022,1975,1899]	2	hSpCas9	negative selection	6900811
74626491	74626514	16	-	27260156	G402	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.6065716033418046	[722]	[1061,326,542,444]	-6	hSpCas9	negative selection	6900812
74652106	74652129	16	-	27260156	G402	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-1.226663527386003	[356]	[265,168,188,132]	-8	hSpCas9	negative selection	6900813
74649190	74649213	16	-	27260156	G402	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.47074440658284067	[393]	[1137,376,813,397]	6	hSpCas9	negative selection	6965067
74644654	74644677	16	-	27260156	G402	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	-0.16274674606025308	[249]	[335,272,318,174]	-2	hSpCas9	negative selection	6965068
74644606	74644629	16	+	27260156	G402	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-2.00422718139016	[325]	[85,67,212,28]	-9	hSpCas9	negative selection	6965069
74626517	74626540	16	+	27260156	L33	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.2819253173859002	[1407]	[1838,716,1008,1649]	6	hSpCas9	negative selection	7022062
74626491	74626514	16	-	27260156	L33	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.2882076305570818	[722]	[660,215,372,584]	-6	hSpCas9	negative selection	7022063
74652106	74652129	16	-	27260156	L33	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	0.07913263769912587	[356]	[511,120,189,394]	1	hSpCas9	negative selection	7022064
74649190	74649213	16	-	27260156	L33	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.305498674224449	[393]	[454,104,171,286]	-6	hSpCas9	negative selection	7086318
74644654	74644677	16	-	27260156	L33	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.06724266827997849	[249]	[357,89,130,258]	1	hSpCas9	negative selection	7086319
74644606	74644629	16	+	27260156	L33	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.4609944166161978	[325]	[193,98,182,221]	-8	hSpCas9	negative selection	7086320
74626517	74626540	16	+	27260156	K562	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.29472412014658067	[1407]	[1549,1162,1631,1736]	3	hSpCas9	negative selection	7143313
74626491	74626514	16	-	27260156	K562	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.4416739960406759	[722]	[445,392,755,305]	-5	hSpCas9	negative selection	7143314
74652106	74652129	16	-	27260156	K562	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	0.45366271332522823	[356]	[525,290,447,464]	6	hSpCas9	negative selection	7143315
74649190	74649213	16	-	27260156	K562	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.023549276825235943	[393]	[280,418,241,421]	0	hSpCas9	negative selection	7207569
74644654	74644677	16	-	27260156	K562	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.07295686524436862	[249]	[170,395,277,105]	0	hSpCas9	negative selection	7207570
74644606	74644629	16	+	27260156	K562	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-1.72089533217201	[325]	[69,33,65,166]	-9	hSpCas9	negative selection	7207571
74626517	74626540	16	+	27260156	HT29	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.3953240096002677	[1407]	[2143,2388,2308,2160]	7	hSpCas9	negative selection	7264564
74626491	74626514	16	-	27260156	HT29	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.018880466777193683	[722]	[1045,743,964,728]	0	hSpCas9	negative selection	7264565
74652106	74652129	16	-	27260156	HT29	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.18419502096251622	[356]	[395,414,461,269]	-4	hSpCas9	negative selection	7264566
74649190	74649213	16	-	27260156	HT29	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.3440872668624849	[393]	[437,455,309,320]	-6	hSpCas9	negative selection	7328820
74644654	74644677	16	-	27260156	HT29	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.07138053620017748	[249]	[425,303,278,277]	1	hSpCas9	negative selection	7328821
74644606	74644629	16	+	27260156	HT29	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.7061130385913861	[325]	[286,253,295,148]	-8	hSpCas9	negative selection	7328822
74626517	74626540	16	+	27260156	MHHES1	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.37730895036210566	[1407]	[2263,2228,2196,1642]	6	hSpCas9	negative selection	7385815
74626491	74626514	16	-	27260156	MHHES1	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.25996634485728476	[722]	[653,795,803,501]	-5	hSpCas9	negative selection	7385816
74652106	74652129	16	-	27260156	MHHES1	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.3201374367658459	[356]	[370,297,292,321]	-6	hSpCas9	negative selection	7385817
74649190	74649213	16	-	27260156	MHHES1	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.24432917123697762	[393]	[334,577,264,335]	-4	hSpCas9	negative selection	7450071
74644654	74644677	16	-	27260156	MHHES1	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	-0.08437424270423133	[249]	[371,253,194,249]	-1	hSpCas9	negative selection	7450072
74644606	74644629	16	+	27260156	MHHES1	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.9505595532707636	[325]	[156,303,209,110]	-9	hSpCas9	negative selection	7450073
74626517	74626540	16	+	27260156	MEWO	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.33193318329923827	[1407]	[1931,1421,1673]	7	hSpCas9	negative selection	7507066
74626491	74626514	16	-	27260156	MEWO	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.33216377132313984	[722]	[685,454,499]	-6	hSpCas9	negative selection	7507067
74652106	74652129	16	-	27260156	MEWO	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.2236083818223204	[356]	[364,153,354]	-5	hSpCas9	negative selection	7507068
74649190	74649213	16	-	27260156	MEWO	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.09186677573969149	[393]	[577,244,259]	-2	hSpCas9	negative selection	7571322
74644654	74644677	16	-	27260156	MEWO	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	-0.36638894601422034	[249]	[225,159,166]	-7	hSpCas9	negative selection	7571323
74644606	74644629	16	+	27260156	MEWO	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.6747876827766237	[325]	[303,191,98]	-8	hSpCas9	negative selection	7571324
74626517	74626540	16	+	27260156	LNCAPCLONEFGC	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.1498629880820268	[1407]	[1516,1176,1461,1523]	2	hSpCas9	negative selection	7628317
74626491	74626514	16	-	27260156	LNCAPCLONEFGC	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	0.03185984696696842	[722]	[642,709,779,558]	0	hSpCas9	negative selection	7628318
74652106	74652129	16	-	27260156	LNCAPCLONEFGC	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.22220486107026088	[356]	[427,201,325,161]	-4	hSpCas9	negative selection	7628319
74649190	74649213	16	-	27260156	LNCAPCLONEFGC	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.1374643488454625	[393]	[327,378,390,473]	2	hSpCas9	negative selection	7692573
74644654	74644677	16	-	27260156	LNCAPCLONEFGC	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.07619728119301195	[249]	[317,106,258,280]	1	hSpCas9	negative selection	7692574
74644606	74644629	16	+	27260156	LNCAPCLONEFGC	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.27989960479928033	[325]	[232,214,358,184]	-4	hSpCas9	negative selection	7692575
74626517	74626540	16	+	27260156	PANC0327	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.3404258071183468	[1407]	[2030,1458,1219,1675]	5	hSpCas9	negative selection	7749568
74626491	74626514	16	-	27260156	PANC0327	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.022938698300077665	[722]	[643,564,687,640]	0	hSpCas9	negative selection	7749569
74652106	74652129	16	-	27260156	PANC0327	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.6463335166620288	[356]	[188,105,344,181]	-7	hSpCas9	negative selection	7749570
74649190	74649213	16	-	27260156	PANC0327	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.36653030404733233	[393]	[492,518,226,559]	5	hSpCas9	negative selection	7813824
74644654	74644677	16	-	27260156	PANC0327	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.3641821756446123	[249]	[393,224,266,273]	5	hSpCas9	negative selection	7813825
74644606	74644629	16	+	27260156	PANC0327	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.9559819190568841	[325]	[240,137,106,119]	-8	hSpCas9	negative selection	7813826
74626517	74626540	16	+	27260156	NCIH2009	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	-0.19001596902086915	[1407]	[1930,1680,1599]	-3	hSpCas9	negative selection	7870819
74626491	74626514	16	-	27260156	NCIH2009	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.42703313915143926	[722]	[803,758,699]	-5	hSpCas9	negative selection	7870820
74652106	74652129	16	-	27260156	NCIH2009	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.587105638678602	[356]	[414,382,212]	-6	hSpCas9	negative selection	7870821
74649190	74649213	16	-	27260156	NCIH2009	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.6269846336331165	[393]	[1243,727,656]	8	hSpCas9	negative selection	7935075
74644654	74644677	16	-	27260156	NCIH2009	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	-0.40611103030791107	[249]	[381,248,182]	-5	hSpCas9	negative selection	7935076
74644606	74644629	16	+	27260156	NCIH2009	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-1.2236041594504237	[325]	[170,251,155]	-8	hSpCas9	negative selection	7935077
74626517	74626540	16	+	27260156	NCIH1373	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.45063839737607747	[1407]	[2437,1674,2109,659]	4	hSpCas9	negative selection	7992070
74626491	74626514	16	-	27260156	NCIH1373	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.05737868727223194	[722]	[727,565,356,401]	0	hSpCas9	negative selection	7992071
74652106	74652129	16	-	27260156	NCIH1373	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.6361689393707681	[356]	[258,385,183,47]	-6	hSpCas9	negative selection	7992072
74649190	74649213	16	-	27260156	NCIH1373	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.23671718044691462	[393]	[312,518,594,163]	2	hSpCas9	negative selection	8056326
74644654	74644677	16	-	27260156	NCIH1373	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.5553583116350954	[249]	[498,162,492,140]	5	hSpCas9	negative selection	8056327
74644606	74644629	16	+	27260156	NCIH1373	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.6017758337865047	[325]	[401,124,71,108]	-5	hSpCas9	negative selection	8056328
74626517	74626540	16	+	27260156	PATU8902	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.3276347068725167	[1407]	[2754,2434,1444,3582]	3	hSpCas9	negative selection	8113321
74626491	74626514	16	-	27260156	PATU8902	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	0.03008566725620554	[722]	[1070,895,1002,1154]	0	hSpCas9	negative selection	8113322
74652106	74652129	16	-	27260156	PATU8902	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.3808191723499021	[356]	[226,639,337,326]	-4	hSpCas9	negative selection	8113323
74649190	74649213	16	-	27260156	PATU8902	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.03017971975105288	[393]	[609,498,204,1075]	0	hSpCas9	negative selection	8177577
74644654	74644677	16	-	27260156	PATU8902	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.9056007132492695	[249]	[570,659,566,852]	8	hSpCas9	negative selection	8177578
74644606	74644629	16	+	27260156	PATU8902	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-2.117526508132821	[325]	[52,133,158,51]	-9	hSpCas9	negative selection	8177579
74626517	74626540	16	+	27260156	PANC1	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.08882571742193601	[1407]	[1348,1516,1320,1025]	1	hSpCas9	negative selection	8234572
74626491	74626514	16	-	27260156	PANC1	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	0.05877062571897662	[722]	[606,689,760,545]	0	hSpCas9	negative selection	8234573
74652106	74652129	16	-	27260156	PANC1	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.8711925389648696	[356]	[169,201,197,113]	-8	hSpCas9	negative selection	8234574
74649190	74649213	16	-	27260156	PANC1	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.15680902848275896	[393]	[260,465,380,409]	2	hSpCas9	negative selection	8298828
74644654	74644677	16	-	27260156	PANC1	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.272817963066153	[249]	[308,292,226,216]	4	hSpCas9	negative selection	8298829
74644606	74644629	16	+	27260156	PANC1	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.8288652585103222	[325]	[141,190,170,134]	-8	hSpCas9	negative selection	8298830
74626517	74626540	16	+	27260156	PANC0813	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.244453233921907	[1407]	[2068,1917,2073,1792]	4	hSpCas9	negative selection	8355823
74626491	74626514	16	-	27260156	PANC0813	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.44237860489417424	[722]	[551,750,652,540]	-6	hSpCas9	negative selection	8355824
74652106	74652129	16	-	27260156	PANC0813	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.49466720294980066	[356]	[318,400,219,253]	-6	hSpCas9	negative selection	8355825
74649190	74649213	16	-	27260156	PANC0813	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	0.31537044293047817	[393]	[687,444,566,610]	5	hSpCas9	negative selection	8420079
74644654	74644677	16	-	27260156	PANC0813	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.5119158454374844	[249]	[682,278,380,358]	7	hSpCas9	negative selection	8420080
74644606	74644629	16	+	27260156	PANC0813	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-1.1036802463537103	[325]	[255,110,179,172]	-8	hSpCas9	negative selection	8420081
74626517	74626540	16	+	27260156	RDES	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.24991009190426583	[1407]	[1547,1886,2054,2300]	4	hSpCas9	negative selection	8477074
74626491	74626514	16	-	27260156	RDES	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.004607082813322005	[722]	[735,770,941,876]	0	hSpCas9	negative selection	8477075
74652106	74652129	16	-	27260156	RDES	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.20072794439127067	[356]	[293,275,408,481]	-3	hSpCas9	negative selection	8477076
74649190	74649213	16	-	27260156	RDES	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.01465214215104732	[393]	[315,443,501,568]	0	hSpCas9	negative selection	8541330
74644654	74644677	16	-	27260156	RDES	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.311226804072291	[249]	[355,261,350,472]	5	hSpCas9	negative selection	8541331
74644606	74644629	16	+	27260156	RDES	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.8708887148590654	[325]	[210,169,214,221]	-9	hSpCas9	negative selection	8541332
74626517	74626540	16	+	27260156	PC3	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.22520925916568402	[1407]	[1194,1563,2648,1559]	5	hSpCas9	negative selection	8598325
74626491	74626514	16	-	27260156	PC3	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.014071636823525524	[722]	[322,528,1023,1253]	0	hSpCas9	negative selection	8598326
74652106	74652129	16	-	27260156	PC3	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.3205551260044284	[356]	[180,284,514,264]	-6	hSpCas9	negative selection	8598327
74649190	74649213	16	-	27260156	PC3	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.2587466371202046	[393]	[249,299,478,340]	-5	hSpCas9	negative selection	8662581
74644654	74644677	16	-	27260156	PC3	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	-0.11475634867436646	[249]	[102,254,251,361]	-3	hSpCas9	negative selection	8662582
74644606	74644629	16	+	27260156	PC3	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.5591113909039704	[325]	[182,228,300,186]	-8	hSpCas9	negative selection	8662583
74626517	74626540	16	+	27260156	PATU8988T	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.09515844161583686	[1407]	[1502,1550,1238,1538]	1	hSpCas9	negative selection	8719576
74626491	74626514	16	-	27260156	PATU8988T	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.02635167451833942	[722]	[606,809,475,880]	0	hSpCas9	negative selection	8719577
74652106	74652129	16	-	27260156	PATU8988T	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.41262861591308225	[356]	[227,252,270,285]	-6	hSpCas9	negative selection	8719578
74649190	74649213	16	-	27260156	PATU8988T	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.07156341493618468	[393]	[451,289,266,440]	-1	hSpCas9	negative selection	8783832
74644654	74644677	16	-	27260156	PATU8988T	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.36104225937673695	[249]	[503,163,319,232]	6	hSpCas9	negative selection	8783833
74644606	74644629	16	+	27260156	PATU8988T	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.8129799480976831	[325]	[203,280,115,121]	-8	hSpCas9	negative selection	8783834
74626517	74626540	16	+	27260156	T47D	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.2596230495350662	[1407]	[2029,1765,1954,2125]	5	hSpCas9	negative selection	8840827
74626491	74626514	16	-	27260156	T47D	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.24713269940556698	[722]	[742,641,726,732]	-5	hSpCas9	negative selection	8840828
74652106	74652129	16	-	27260156	T47D	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.5949081467666368	[356]	[288,265,236,311]	-8	hSpCas9	negative selection	8840829
74649190	74649213	16	-	27260156	T47D	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.3077027279374557	[393]	[407,343,278,458]	-6	hSpCas9	negative selection	8905083
74644654	74644677	16	-	27260156	T47D	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.17989939760586293	[249]	[305,338,332,340]	4	hSpCas9	negative selection	8905084
74644606	74644629	16	+	27260156	T47D	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.8055451095056043	[325]	[149,218,253,245]	-9	hSpCas9	negative selection	8905085
74626517	74626540	16	+	27260156	SU8686	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.2535771815964494	[1407]	[1578,1401,1910,1829]	4	hSpCas9	negative selection	8962078
74626491	74626514	16	-	27260156	SU8686	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.2588986964543865	[722]	[470,585,609,768]	-4	hSpCas9	negative selection	8962079
74652106	74652129	16	-	27260156	SU8686	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.10312173209680991	[356]	[362,290,307,358]	-2	hSpCas9	negative selection	8962080
74649190	74649213	16	-	27260156	SU8686	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.138117245812305	[393]	[413,304,395,292]	-2	hSpCas9	negative selection	9026334
74644654	74644677	16	-	27260156	SU8686	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.11176304554223726	[249]	[170,234,344,348]	1	hSpCas9	negative selection	9026335
74644606	74644629	16	+	27260156	SU8686	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.7510163085374215	[325]	[199,213,111,242]	-8	hSpCas9	negative selection	9026336
74626517	74626540	16	+	27260156	SKES1	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.15682994820568075	[1407]	[1751,1860,1345,1374]	3	hSpCas9	negative selection	9083329
74626491	74626514	16	-	27260156	SKES1	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.2862839403361315	[722]	[569,760,626,436]	-6	hSpCas9	negative selection	9083330
74652106	74652129	16	-	27260156	SKES1	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.45371059843958067	[356]	[317,302,214,219]	-7	hSpCas9	negative selection	9083331
74649190	74649213	16	-	27260156	SKES1	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.16596762486523065	[393]	[353,385,230,423]	-4	hSpCas9	negative selection	9147585
74644654	74644677	16	-	27260156	SKES1	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.12729400871386654	[249]	[362,319,217,211]	2	hSpCas9	negative selection	9147586
74644606	74644629	16	+	27260156	SKES1	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.7716622974851914	[325]	[301,214,166,104]	-9	hSpCas9	negative selection	9147587
74626517	74626540	16	+	27260156	TOV112D	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.3096520760043	[1407]	[1840,2024,1546,1653]	6	hSpCas9	negative selection	9204580
74626491	74626514	16	-	27260156	TOV112D	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.3222392681011757	[722]	[609,965,456,385]	-6	hSpCas9	negative selection	9204581
74652106	74652129	16	-	27260156	TOV112D	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.4619030472729447	[356]	[263,222,343,199]	-7	hSpCas9	negative selection	9204582
74649190	74649213	16	-	27260156	TOV112D	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.015098255244805125	[393]	[304,477,376,414]	0	hSpCas9	negative selection	9268836
74644654	74644677	16	-	27260156	TOV112D	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	0.14113209380277947	[249]	[219,505,230,200]	2	hSpCas9	negative selection	9268837
74644606	74644629	16	+	27260156	TOV112D	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-1.2118998398225682	[325]	[232,125,152,57]	-9	hSpCas9	negative selection	9268838
74626517	74626540	16	+	27260156	TC71	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.294602542934548	[1407]	[2046,1751,1708,1899]	7	hSpCas9	negative selection	9325831
74626491	74626514	16	-	27260156	TC71	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.04312808544489377	[722]	[833,762,539,884]	-1	hSpCas9	negative selection	9325832
74652106	74652129	16	-	27260156	TC71	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	0.020903600989995996	[356]	[380,435,353,382]	0	hSpCas9	negative selection	9325833
74649190	74649213	16	-	27260156	TC71	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.22232915399305647	[393]	[345,433,329,337]	-5	hSpCas9	negative selection	9390087
74644654	74644677	16	-	27260156	TC71	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	-0.13114253884725813	[249]	[248,283,212,232]	-3	hSpCas9	negative selection	9390088
74644606	74644629	16	+	27260156	TC71	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.6241248469073988	[325]	[213,252,199,241]	-9	hSpCas9	negative selection	9390089
74626517	74626540	16	+	27260156	TC32	viability	TTCCATCAGCACACTTCGTATGG	RFWD3	ENSG00000168411	0.10358377293913934	[1407]	[1302,1108,1879,1527]	2	hSpCas9	negative selection	9447082
74626491	74626514	16	-	27260156	TC32	viability	TCCTACCGACTGGATGACACTGG	RFWD3	ENSG00000168411	-0.14508125179379683	[722]	[487,567,677,736]	-3	hSpCas9	negative selection	9447083
74652106	74652129	16	-	27260156	TC32	viability	ACATAGGTTGAGAGCACCATTGG	RFWD3	ENSG00000168411	-0.9413265341412542	[356]	[212,69,242,211]	-9	hSpCas9	negative selection	9447084
74649190	74649213	16	-	27260156	TC32	viability	GACTTGGCAGAGCAACTAGCAGG	RFWD3	ENSG00000168411	-0.38639976275840016	[393]	[259,203,439,271]	-6	hSpCas9	negative selection	9511338
74644654	74644677	16	-	27260156	TC32	viability	GGACACTTGTACAATATGTCTGG	RFWD3	ENSG00000168411	-0.007794098773134195	[249]	[280,97,318,286]	0	hSpCas9	negative selection	9511339
74644606	74644629	16	+	27260156	TC32	viability	CACAGCGTAATGCTGAGAGCCGG	RFWD3	ENSG00000168411	-0.6211710227534668	[325]	[208,155,202,233]	-8	hSpCas9	negative selection	9511340
74632590	74632613	16	-	27869803	HPAFII	viability after 27 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-1.4985925443161736	[535]	[180,31,NaN]	-7	hSpCas9	negative selection	9558377
74636484	74636507	16	-	27869803	HPAFII	viability after 27 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.2537213353379283	[142]	[93,85,NaN]	2	hSpCas9	negative selection	9558378
74644375	74644398	16	-	27869803	HPAFII	viability after 27 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	0.32876992277833283	[432]	[148,399,NaN]	2	hSpCas9	negative selection	9558379
74644609	74644632	16	+	27869803	HPAFII	viability after 27 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-2.6626986437212152	[172]	[3,22,NaN]	-8	hSpCas9	negative selection	9558380
74652083	74652106	16	-	27869803	HPAFII	viability after 27 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	0.7110053596345697	[149]	[193,74,NaN]	6	hSpCas9	negative selection	9558381
74661307	74661330	16	-	27869803	HPAFII	viability after 27 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.7214898453683561	[139]	[194,59,NaN]	6	hSpCas9	negative selection	9558382
74632590	74632613	16	-	27869803	HPAFII	viability after 15 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-0.8029613433964086	[535]	[278,361,NaN]	-7	hSpCas9	negative selection	9640826
74636484	74636507	16	-	27869803	HPAFII	viability after 15 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.772124063115239	[142]	[222,286,NaN]	8	hSpCas9	negative selection	9640827
74644375	74644398	16	-	27869803	HPAFII	viability after 15 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-0.009080848061818414	[432]	[512,430,NaN]	0	hSpCas9	negative selection	9640828
74644609	74644632	16	+	27869803	HPAFII	viability after 15 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.233531742078176	[172]	[120,52,NaN]	-8	hSpCas9	negative selection	9640829
74652083	74652106	16	-	27869803	HPAFII	viability after 15 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	0.17289936750953594	[149]	[198,170,NaN]	2	hSpCas9	negative selection	9640830
74661307	74661330	16	-	27869803	HPAFII	viability after 15 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.27239296382844225	[139]	[317,96,NaN]	3	hSpCas9	negative selection	9640831
74632590	74632613	16	-	27869803	ASPC1	viability after 36 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-0.8253098385746271	[1288]	[257,421,114]	-7	hSpCas9	negative selection	9723275
74636484	74636507	16	-	27869803	ASPC1	viability after 36 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.06436550817001052	[488]	[195,290,74]	0	hSpCas9	negative selection	9723276
74644375	74644398	16	-	27869803	ASPC1	viability after 36 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-0.27182398925237383	[907]	[214,370,206]	-3	hSpCas9	negative selection	9723277
74644609	74644632	16	+	27869803	ASPC1	viability after 36 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-1.409881662077376	[344]	[83,49,13]	-8	hSpCas9	negative selection	9723278
74652083	74652106	16	-	27869803	ASPC1	viability after 36 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	0.023283939559335498	[334]	[195,63,106]	0	hSpCas9	negative selection	9723279
74661307	74661330	16	-	27869803	ASPC1	viability after 36 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.2595470857207465	[293]	[25,285,59]	2	hSpCas9	negative selection	9723280
74632590	74632613	16	-	27869803	PATU8988S	viability after 35 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	0.3012627030295867	[1051]	[558,484,NaN]	3	hSpCas9	negative selection	9805724
74636484	74636507	16	-	27869803	PATU8988S	viability after 35 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	1.3282277517065721	[316]	[353,286,NaN]	9	hSpCas9	negative selection	9805725
74644375	74644398	16	-	27869803	PATU8988S	viability after 35 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	0.056379721584728815	[778]	[214,437,NaN]	0	hSpCas9	negative selection	9805726
74644609	74644632	16	+	27869803	PATU8988S	viability after 35 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-0.5428350402980058	[312]	[99,72,NaN]	-5	hSpCas9	negative selection	9805727
74652083	74652106	16	-	27869803	PATU8988S	viability after 35 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	0.3254386587062093	[335]	[198,139,NaN]	4	hSpCas9	negative selection	9805728
74661307	74661330	16	-	27869803	PATU8988S	viability after 35 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	1.7054204736844178	[197]	[288,230,NaN]	9	hSpCas9	negative selection	9805729
74632590	74632613	16	-	27869803	PATU8988S	viability after 31 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	0.47060682127876086	[1051]	[520,657,NaN]	5	hSpCas9	negative selection	9888173
74636484	74636507	16	-	27869803	PATU8988S	viability after 31 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	1.151937320654057	[316]	[279,281,NaN]	9	hSpCas9	negative selection	9888174
74644375	74644398	16	-	27869803	PATU8988S	viability after 31 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	0.09041933746977993	[778]	[291,379,NaN]	1	hSpCas9	negative selection	9888175
74644609	74644632	16	+	27869803	PATU8988S	viability after 31 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-0.49043037022844094	[312]	[83,94,NaN]	-5	hSpCas9	negative selection	9888176
74652083	74652106	16	-	27869803	PATU8988S	viability after 31 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	-0.2584953092711523	[335]	[111,111,NaN]	-3	hSpCas9	negative selection	9888177
74661307	74661330	16	-	27869803	PATU8988S	viability after 31 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	1.4388679814776917	[197]	[228,194,NaN]	9	hSpCas9	negative selection	9888178
74632590	74632613	16	-	27869803	HPAFII	viability after 35 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-0.7161240739456362	[535]	[167,161,NaN]	-4	hSpCas9	negative selection	9970622
74636484	74636507	16	-	27869803	HPAFII	viability after 35 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.2883077872887658	[142]	[78,98,NaN]	1	hSpCas9	negative selection	9970623
74644375	74644398	16	-	27869803	HPAFII	viability after 35 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	-0.03352233040074115	[432]	[81,362,NaN]	0	hSpCas9	negative selection	9970624
74644609	74644632	16	+	27869803	HPAFII	viability after 35 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-3.1220833083713018	[172]	[10,8,NaN]	-8	hSpCas9	negative selection	9970625
74652083	74652106	16	-	27869803	HPAFII	viability after 35 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	1.007262117382542	[149]	[257,33,NaN]	6	hSpCas9	negative selection	9970626
74661307	74661330	16	-	27869803	HPAFII	viability after 35 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.8147984816504308	[139]	[174,67,NaN]	5	hSpCas9	negative selection	9970627
74632590	74632613	16	-	27869803	HPAFII	viability after 31 days	TGGCAAACAGATCCGTGGACTGG	RFWD3	ENSG00000168411	-1.5471181785096193	[535]	[134,67,NaN]	-7	hSpCas9	negative selection	10053071
74636484	74636507	16	-	27869803	HPAFII	viability after 31 days	GAGCTGCTCACCCTCCAGCCAGG	RFWD3	ENSG00000168411	0.3354815011659322	[142]	[95,106,NaN]	2	hSpCas9	negative selection	10053072
74644375	74644398	16	-	27869803	HPAFII	viability after 31 days	AGCTTTGGACACTAGTGAACAGG	RFWD3	ENSG00000168411	0.2598462557435671	[432]	[144,449,NaN]	1	hSpCas9	negative selection	10053073
74644609	74644632	16	+	27869803	HPAFII	viability after 31 days	AGCGTAATGCTGAGAGCCGGTGG	RFWD3	ENSG00000168411	-2.906376835162275	[172]	[22,1,NaN]	-8	hSpCas9	negative selection	10053074
74652083	74652106	16	-	27869803	HPAFII	viability after 31 days	ATGCTTACTTTCAGGTGAGCAGG	RFWD3	ENSG00000168411	0.844866838513087	[149]	[177,121,NaN]	6	hSpCas9	negative selection	10053075
74661307	74661330	16	-	27869803	HPAFII	viability after 31 days	GCTGATGTGGTCAGCAGCCAGGG	RFWD3	ENSG00000168411	0.42421026673308326	[139]	[114,94,NaN]	3	hSpCas9	negative selection	10053076
74660970	74660993	16	-	28162770	P31FUJ	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-1.638058682900637	[97]	[36]	-8	hSpCas9	negative selection	10224376
74661136	74661159	16	-	28162770	P31FUJ	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	0.10930377241061409	[212]	[269]	1	hSpCas9	negative selection	10224377
74661376	74661399	16	-	28162770	P31FUJ	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.04837954812967471	[78]	[95]	0	hSpCas9	negative selection	10224378
74661326	74661349	16	+	28162770	P31FUJ	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	0.9154277259286149	[133]	[296]	9	hSpCas9	negative selection	10224379
74661197	74661220	16	-	28162770	P31FUJ	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	-0.22719949818500276	[256]	[257]	-2	hSpCas9	negative selection	10224380
74644692	74644715	16	+	28162770	P31FUJ	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-1.1707412362821272	[363]	[189]	-7	hSpCas9	negative selection	10224381
74644633	74644656	16	-	28162770	P31FUJ	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-2.0306133538011117	[225]	[64]	-8	hSpCas9	negative selection	10224382
74636525	74636548	16	-	28162770	P31FUJ	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-1.3381552045606073	[141]	[65]	-7	hSpCas9	negative selection	10224383
74661431	74661454	16	-	28162770	P31FUJ	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.07128457771279659	[178]	[220]	0	hSpCas9	negative selection	10224384
74661224	74661247	16	+	28162770	P31FUJ	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	-1.3045928874823884	[102]	[48]	-7	hSpCas9	negative selection	10224385
74660970	74660993	16	-	28162770	TF1	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10393742
74661136	74661159	16	-	28162770	TF1	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	NaN	[NaN]	[216]	1	hSpCas9	negative selection	10393743
74661376	74661399	16	-	28162770	TF1	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10393744
74661326	74661349	16	+	28162770	TF1	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	NaN	[NaN]	[52]	1	hSpCas9	negative selection	10393745
74661197	74661220	16	-	28162770	TF1	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	NaN	[NaN]	[208]	1	hSpCas9	negative selection	10393746
74644692	74644715	16	+	28162770	TF1	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10393747
74644633	74644656	16	-	28162770	TF1	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10393748
74636525	74636548	16	-	28162770	TF1	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	NaN	[NaN]	[68]	1	hSpCas9	negative selection	10393749
74661431	74661454	16	-	28162770	TF1	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	NaN	[NaN]	[236]	1	hSpCas9	negative selection	10393750
74661224	74661247	16	+	28162770	TF1	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10393751
74660970	74660993	16	-	28162770	SKM1	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-3.4069641987431614	[23]	[3]	-9	hSpCas9	negative selection	10563108
74661136	74661159	16	-	28162770	SKM1	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-0.913149586080201	[48]	[45]	-6	hSpCas9	negative selection	10563109
74661376	74661399	16	-	28162770	SKM1	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.3300013954230443	[17]	[39]	3	hSpCas9	negative selection	10563110
74661326	74661349	16	+	28162770	SKM1	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	0.29901370293936036	[39]	[86]	3	hSpCas9	negative selection	10563111
74661197	74661220	16	-	28162770	SKM1	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	-0.06457200129608387	[83]	[141]	0	hSpCas9	negative selection	10563112
74644692	74644715	16	+	28162770	SKM1	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-1.0753859338220801	[148]	[124]	-7	hSpCas9	negative selection	10563113
74644633	74644656	16	-	28162770	SKM1	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-2.09884190338083	[62]	[25]	-8	hSpCas9	negative selection	10563114
74636525	74636548	16	-	28162770	SKM1	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-0.6355885737911244	[28]	[32]	-5	hSpCas9	negative selection	10563115
74661431	74661454	16	-	28162770	SKM1	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	1.0336083926428197	[20]	[75]	8	hSpCas9	negative selection	10563116
74661224	74661247	16	+	28162770	SKM1	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	0.277533975528909	[13]	[29]	2	hSpCas9	negative selection	10563117
74660970	74660993	16	-	28162770	SKM1	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-3.4069641987431614	[23]	[3]	-9	hSpCas9	negative selection	10732474
74661136	74661159	16	-	28162770	SKM1	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-0.913149586080201	[48]	[45]	-6	hSpCas9	negative selection	10732475
74661376	74661399	16	-	28162770	SKM1	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.3300013954230443	[17]	[39]	3	hSpCas9	negative selection	10732476
74661326	74661349	16	+	28162770	SKM1	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	0.29901370293936036	[39]	[86]	3	hSpCas9	negative selection	10732477
74661197	74661220	16	-	28162770	SKM1	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	-0.06457200129608387	[83]	[141]	0	hSpCas9	negative selection	10732478
74644692	74644715	16	+	28162770	SKM1	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-1.0753859338220801	[148]	[124]	-7	hSpCas9	negative selection	10732479
74644633	74644656	16	-	28162770	SKM1	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-2.09884190338083	[62]	[25]	-8	hSpCas9	negative selection	10732480
74636525	74636548	16	-	28162770	SKM1	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-0.6355885737911244	[28]	[32]	-5	hSpCas9	negative selection	10732481
74661431	74661454	16	-	28162770	SKM1	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	1.0336083926428197	[20]	[75]	8	hSpCas9	negative selection	10732482
74661224	74661247	16	+	28162770	SKM1	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	0.277533975528909	[13]	[29]	2	hSpCas9	negative selection	10732483
74660970	74660993	16	-	28162770	PL21	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-2.369715993841628	[94]	[7]	-8	hSpCas9	negative selection	10901840
74661136	74661159	16	-	28162770	PL21	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	0.893250919066099	[166]	[134]	7	hSpCas9	negative selection	10901841
74661376	74661399	16	-	28162770	PL21	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	-0.5256854220716856	[85]	[25]	-4	hSpCas9	negative selection	10901842
74661326	74661349	16	+	28162770	PL21	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	-0.6188343908351174	[186]	[52]	-4	hSpCas9	negative selection	10901843
74661197	74661220	16	-	28162770	PL21	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	1.0509460546310943	[284]	[256]	8	hSpCas9	negative selection	10901844
74644692	74644715	16	+	28162770	PL21	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-0.3054546475363452	[388]	[136]	-2	hSpCas9	negative selection	10901845
74644633	74644656	16	-	28162770	PL21	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-0.10132437783832662	[174]	[70]	0	hSpCas9	negative selection	10901846
74636525	74636548	16	-	28162770	PL21	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-0.2592920041479774	[87]	[31]	-2	hSpCas9	negative selection	10901847
74661431	74661454	16	-	28162770	PL21	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.7526806375180987	[104]	[76]	6	hSpCas9	negative selection	10901848
74661224	74661247	16	+	28162770	PL21	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	0.4819105829046999	[50]	[30]	4	hSpCas9	negative selection	10901849
74660970	74660993	16	-	28162770	P31FUJ	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-1.638058682900637	[97]	[36]	-8	hSpCas9	negative selection	11071206
74661136	74661159	16	-	28162770	P31FUJ	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	0.10930377241061409	[212]	[269]	1	hSpCas9	negative selection	11071207
74661376	74661399	16	-	28162770	P31FUJ	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.04837954812967471	[78]	[95]	0	hSpCas9	negative selection	11071208
74661326	74661349	16	+	28162770	P31FUJ	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	0.9154277259286149	[133]	[296]	9	hSpCas9	negative selection	11071209
74661197	74661220	16	-	28162770	P31FUJ	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	-0.22719949818500276	[256]	[257]	-2	hSpCas9	negative selection	11071210
74644692	74644715	16	+	28162770	P31FUJ	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-1.1707412362821272	[363]	[189]	-7	hSpCas9	negative selection	11071211
74644633	74644656	16	-	28162770	P31FUJ	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-2.0306133538011117	[225]	[64]	-8	hSpCas9	negative selection	11071212
74636525	74636548	16	-	28162770	P31FUJ	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-1.3381552045606073	[141]	[65]	-7	hSpCas9	negative selection	11071213
74661431	74661454	16	-	28162770	P31FUJ	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.07128457771279659	[178]	[220]	0	hSpCas9	negative selection	11071214
74661224	74661247	16	+	28162770	P31FUJ	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	-1.3045928874823884	[102]	[48]	-7	hSpCas9	negative selection	11071215
74660970	74660993	16	-	28162770	OCIAML5	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-0.5345843810078268	[64]	[80]	-4	hSpCas9	negative selection	11240572
74661136	74661159	16	-	28162770	OCIAML5	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-0.6777363903016834	[217]	[245]	-4	hSpCas9	negative selection	11240573
74661376	74661399	16	-	28162770	OCIAML5	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	-0.3468312626135751	[61]	[87]	-2	hSpCas9	negative selection	11240574
74661326	74661349	16	+	28162770	OCIAML5	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	-0.9377964448898808	[51]	[48]	-5	hSpCas9	negative selection	11240575
74661197	74661220	16	-	28162770	OCIAML5	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	0.2657699194298614	[140]	[305]	2	hSpCas9	negative selection	11240576
74644692	74644715	16	+	28162770	OCIAML5	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-1.1296005463929057	[279]	[230]	-6	hSpCas9	negative selection	11240577
74644633	74644656	16	-	28162770	OCIAML5	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-2.8417246266425376	[138]	[34]	-8	hSpCas9	negative selection	11240578
74636525	74636548	16	-	28162770	OCIAML5	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-1.895135292755883	[67]	[32]	-7	hSpCas9	negative selection	11240579
74661431	74661454	16	-	28162770	OCIAML5	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.023306774622258164	[144]	[265]	0	hSpCas9	negative selection	11240580
74661224	74661247	16	+	28162770	OCIAML5	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	-1.958981774780509	[55]	[25]	-8	hSpCas9	negative selection	11240581
74660970	74660993	16	-	28162770	EOL1	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-3.0854363170020878	[144]	[8]	-9	hSpCas9	negative selection	11409938
74661136	74661159	16	-	28162770	EOL1	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-0.2956504363530015	[218]	[93]	-2	hSpCas9	negative selection	11409939
74661376	74661399	16	-	28162770	EOL1	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	1.0400249889904705	[131]	[142]	8	hSpCas9	negative selection	11409940
74661326	74661349	16	+	28162770	EOL1	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	0.5199722111103153	[228]	[172]	5	hSpCas9	negative selection	11409941
74661197	74661220	16	-	28162770	EOL1	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	-0.14555646689381396	[505]	[240]	-1	hSpCas9	negative selection	11409942
74644692	74644715	16	+	28162770	EOL1	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-0.9798228320594684	[714]	[190]	-6	hSpCas9	negative selection	11409943
74644633	74644656	16	-	28162770	EOL1	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-2.0283182528383707	[270]	[34]	-8	hSpCas9	negative selection	11409944
74636525	74636548	16	-	28162770	EOL1	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-1.5631175277957066	[128]	[22]	-7	hSpCas9	negative selection	11409945
74661431	74661454	16	-	28162770	EOL1	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.6690470384221482	[190]	[159]	6	hSpCas9	negative selection	11409946
74661224	74661247	16	+	28162770	EOL1	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	2.4139326123094595	[77]	[218]	9	hSpCas9	negative selection	11409947
74660970	74660993	16	-	28162770	MOLM13	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-1.636447278270157	[85]	[19]	-7	hSpCas9	negative selection	11579304
74661136	74661159	16	-	28162770	MOLM13	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-0.9695159307627197	[324]	[119]	-5	hSpCas9	negative selection	11579305
74661376	74661399	16	-	28162770	MOLM13	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.07123041158058951	[103]	[78]	0	hSpCas9	negative selection	11579306
74661326	74661349	16	+	28162770	MOLM13	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	0.6520117859533097	[190]	[216]	5	hSpCas9	negative selection	11579307
74661197	74661220	16	-	28162770	MOLM13	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	-0.0751557301103366	[423]	[290]	0	hSpCas9	negative selection	11579308
74644692	74644715	16	+	28162770	MOLM13	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-1.0510755604023374	[469]	[163]	-5	hSpCas9	negative selection	11579309
74644633	74644656	16	-	28162770	MOLM13	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-2.2426040012604362	[287]	[43]	-7	hSpCas9	negative selection	11579310
74636525	74636548	16	-	28162770	MOLM13	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-3.0210462314028015	[246]	[21]	-8	hSpCas9	negative selection	11579311
74661431	74661454	16	-	28162770	MOLM13	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.24200797412825095	[206]	[176]	1	hSpCas9	negative selection	11579312
74661224	74661247	16	+	28162770	MOLM13	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	-1.8875912730538098	[86]	[16]	-7	hSpCas9	negative selection	11579313
74660970	74660993	16	-	28162770	HEL	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	0.28256326775603147	[85]	[66]	2	hSpCas9	negative selection	11748670
74661136	74661159	16	-	28162770	HEL	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-0.11939733790075521	[211]	[124]	-1	hSpCas9	negative selection	11748671
74661376	74661399	16	-	28162770	HEL	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.41803254482566243	[103]	[88]	3	hSpCas9	negative selection	11748672
74661326	74661349	16	+	28162770	HEL	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	1.1800667610826288	[194]	[282]	9	hSpCas9	negative selection	11748673
74661197	74661220	16	-	28162770	HEL	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	0.1691976139476239	[410]	[295]	1	hSpCas9	negative selection	11748674
74644692	74644715	16	+	28162770	HEL	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-0.12642367840693836	[437]	[256]	-1	hSpCas9	negative selection	11748675
74644633	74644656	16	-	28162770	HEL	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-2.610602177629593	[266]	[27]	-8	hSpCas9	negative selection	11748676
74636525	74636548	16	-	28162770	HEL	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-0.24622985561089927	[149]	[80]	-2	hSpCas9	negative selection	11748677
74661431	74661454	16	-	28162770	HEL	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.16722747369519791	[202]	[145]	1	hSpCas9	negative selection	11748678
74661224	74661247	16	+	28162770	HEL	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	-0.3777252705593588	[70]	[34]	-3	hSpCas9	negative selection	11748679
74660970	74660993	16	-	28162770	MV411	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-1.8745529735958348	[73]	[16]	-8	hSpCas9	negative selection	11918036
74661136	74661159	16	-	28162770	MV411	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-0.5122993510420891	[148]	[87]	-4	hSpCas9	negative selection	11918037
74661376	74661399	16	-	28162770	MV411	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	-0.5025841962088771	[73]	[43]	-4	hSpCas9	negative selection	11918038
74661326	74661349	16	+	28162770	MV411	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	-1.0155968550510186	[119]	[49]	-6	hSpCas9	negative selection	11918039
74661197	74661220	16	-	28162770	MV411	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	-0.43383205428891186	[270]	[168]	-3	hSpCas9	negative selection	11918040
74644692	74644715	16	+	28162770	MV411	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-0.3966254621649633	[435]	[278]	-3	hSpCas9	negative selection	11918041
74644633	74644656	16	-	28162770	MV411	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-0.9659660873264179	[159]	[68]	-6	hSpCas9	negative selection	11918042
74636525	74636548	16	-	28162770	MV411	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-0.8614968207703886	[109]	[50]	-5	hSpCas9	negative selection	11918043
74661431	74661454	16	-	28162770	MV411	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.5654076321014543	[145]	[181]	5	hSpCas9	negative selection	11918044
74661224	74661247	16	+	28162770	MV411	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	-2.103059696301358	[50]	[9]	-8	hSpCas9	negative selection	11918045
74660970	74660993	16	-	28162770	MONOMAC1	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-2.3776090927013747	[67]	[14]	-9	hSpCas9	negative selection	12087402
74661136	74661159	16	-	28162770	MONOMAC1	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	0.5326054063007937	[78]	[130]	5	hSpCas9	negative selection	12087403
74661376	74661399	16	-	28162770	MONOMAC1	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	-0.8447351031286725	[46]	[29]	-6	hSpCas9	negative selection	12087404
74661326	74661349	16	+	28162770	MONOMAC1	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	0.12224166941385922	[108]	[135]	1	hSpCas9	negative selection	12087405
74661197	74661220	16	-	28162770	MONOMAC1	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	-0.13691585462198297	[187]	[195]	-1	hSpCas9	negative selection	12087406
74644692	74644715	16	+	28162770	MONOMAC1	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	0.026892809415292263	[267]	[312]	0	hSpCas9	negative selection	12087407
74644633	74644656	16	-	28162770	MONOMAC1	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-0.493021674694634	[123]	[100]	-4	hSpCas9	negative selection	12087408
74636525	74636548	16	-	28162770	MONOMAC1	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-0.5755484703132835	[64]	[49]	-5	hSpCas9	negative selection	12087409
74661431	74661454	16	-	28162770	MONOMAC1	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	-0.7008032649327289	[94]	[66]	-5	hSpCas9	negative selection	12087410
74661224	74661247	16	+	28162770	MONOMAC1	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	0.23264742818369166	[48]	[65]	2	hSpCas9	negative selection	12087411
74660970	74660993	16	-	28162770	OCIAML2	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-0.5637392296336425	[15]	[59]	-4	hSpCas9	negative selection	12256768
74661136	74661159	16	-	28162770	OCIAML2	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-0.06463746556632435	[29]	[158]	0	hSpCas9	negative selection	12256769
74661376	74661399	16	-	28162770	OCIAML2	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	-1.068531381670816	[13]	[36]	-6	hSpCas9	negative selection	12256770
74661326	74661349	16	+	28162770	OCIAML2	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	0.10468250544527569	[24]	[148]	1	hSpCas9	negative selection	12256771
74661197	74661220	16	-	28162770	OCIAML2	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	-0.11122702493613594	[37]	[194]	-1	hSpCas9	negative selection	12256772
74644692	74644715	16	+	28162770	OCIAML2	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	-0.22962172573836626	[65]	[311]	-2	hSpCas9	negative selection	12256773
74644633	74644656	16	-	28162770	OCIAML2	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-1.7982044832706654	[31]	[50]	-8	hSpCas9	negative selection	12256774
74636525	74636548	16	-	28162770	OCIAML2	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-1.3881676650501882	[16]	[35]	-7	hSpCas9	negative selection	12256775
74661431	74661454	16	-	28162770	OCIAML2	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	-0.7028032673711945	[36]	[125]	-5	hSpCas9	negative selection	12256776
74661224	74661247	16	+	28162770	OCIAML2	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	-0.7336642310759549	[11]	[39]	-5	hSpCas9	negative selection	12256777
74660970	74660993	16	-	28162770	OCIAML3	viability	GGAGGGTATCTGCTTCACGGAGG	RFWD3	ENSG00000168411	-1.700922844240675	[13]	[12]	-8	hSpCas9	negative selection	12426134
74661136	74661159	16	-	28162770	OCIAML3	viability	ACTTCAGAACAACATAGGCAGGG	RFWD3	ENSG00000168411	-0.009045139603006978	[54]	[164]	0	hSpCas9	negative selection	12426135
74661376	74661399	16	-	28162770	OCIAML3	viability	GAACAACAGCCAGCTCCTGCTGG	RFWD3	ENSG00000168411	0.5055280332267511	[20]	[89]	5	hSpCas9	negative selection	12426136
74661326	74661349	16	+	28162770	OCIAML3	viability	CAGCAGGAACAGGCTGGAGGAGG	RFWD3	ENSG00000168411	0.40599235967583686	[28]	[115]	4	hSpCas9	negative selection	12426137
74661197	74661220	16	-	28162770	OCIAML3	viability	TGTTGACCTGACAGAAGTGGAGG	RFWD3	ENSG00000168411	-0.15129772256076468	[70]	[192]	-1	hSpCas9	negative selection	12426138
74644692	74644715	16	+	28162770	OCIAML3	viability	ATAGAAGCAGAAGGTAGCAGAGG	RFWD3	ENSG00000168411	0.28181294845510696	[96]	[355]	2	hSpCas9	negative selection	12426139
74644633	74644656	16	-	28162770	OCIAML3	viability	GGAACAGTGGACCAATGCTGGGG	RFWD3	ENSG00000168411	-0.7949203342501596	[49]	[86]	-5	hSpCas9	negative selection	12426140
74636525	74636548	16	-	28162770	OCIAML3	viability	CAGAATTTACAGCAACCCAGGGG	RFWD3	ENSG00000168411	-1.0755405513899137	[36]	[52]	-6	hSpCas9	negative selection	12426141
74661431	74661454	16	-	28162770	OCIAML3	viability	AGTGATGGCTCATGAAGCAATGG	RFWD3	ENSG00000168411	0.3157945507042587	[32]	[123]	3	hSpCas9	negative selection	12426142
74661224	74661247	16	+	28162770	OCIAML3	viability	GTTGCGGAGCAGGCTGGAGCAGG	RFWD3	ENSG00000168411	0.21334728173344097	[21]	[76]	2	hSpCas9	negative selection	12426143