Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 6041
  • Symbol: RNASEL
  • Description: ribonuclease L
DataSource: http://genomecrispr.dkfz.de/#!/results/RNASEL

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
182586302 182586325 1 - 26472758 Jiyoye viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 -0.21797620933098177 [90] [58] -1 hSpCas9 negative selection 137715
182585617 182585640 1 - 26472758 Jiyoye viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 0.6891513509931274 [226] [275] 5 hSpCas9 negative selection 137716
182585846 182585869 1 + 26472758 Jiyoye viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 0.4071753815058732 [346] [346] 3 hSpCas9 negative selection 137717
182585723 182585746 1 + 26472758 Jiyoye viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.7705234037732166 [205] [264] 5 hSpCas9 negative selection 137718
182585598 182585621 1 - 26472758 Jiyoye viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 1.3944643297563193 [56] [112] 8 hSpCas9 negative selection 137719
182586754 182586777 1 - 26472758 Jiyoye viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.4385778309096152 [256] [142] -3 hSpCas9 negative selection 137720
182586329 182586352 1 - 26472758 Jiyoye viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 -2.914752713381489 [129] [12] -9 hSpCas9 negative selection 137721
182586233 182586256 1 - 26472758 Jiyoye viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 -1.7910942456304004 [256] [55] -8 hSpCas9 negative selection 137722
182585776 182585799 1 - 26472758 Jiyoye viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 0.0323269723427284 [117] [90] 0 hSpCas9 negative selection 137723
182585661 182585684 1 - 26472758 Jiyoye viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 -0.6326256265521014 [293] [142] -4 hSpCas9 negative selection 137724
182586302 182586325 1 - 26472758 KBM7 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 0.43411296204744226 [280,337] [266,138] 5 hSpCas9 negative selection 328833
182585617 182585640 1 - 26472758 KBM7 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 0.44787960791621906 [1383,1624] [1033,926] 5 hSpCas9 negative selection 328834
182585846 182585869 1 + 26472758 KBM7 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 0.2064219435574568 [1097,846] [679,382] 2 hSpCas9 negative selection 328835
182585723 182585746 1 + 26472758 KBM7 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 -0.0487188390084925 [1572,1060] [623,558] 0 hSpCas9 negative selection 328836
182585598 182585621 1 - 26472758 KBM7 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 1.0091404178293601 [400,311] [377,295] 9 hSpCas9 negative selection 328837
182586754 182586777 1 - 26472758 KBM7 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 0.46608578270605716 [728,723] [511,439] 5 hSpCas9 negative selection 328838
182586329 182586352 1 - 26472758 KBM7 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 -0.5538101175771606 [181,199] [84,40] -5 hSpCas9 negative selection 328839
182586233 182586256 1 - 26472758 KBM7 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 -0.24532817509586846 [719,443] [171,274] -2 hSpCas9 negative selection 328840
182585776 182585799 1 - 26472758 KBM7 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 0.002809524801444252 [364,377] [219,136] 0 hSpCas9 negative selection 328841
182585661 182585684 1 - 26472758 KBM7 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 0.5677314863325882 [893,939] [552,724] 6 hSpCas9 negative selection 328842
182586302 182586325 1 - 26472758 Raji viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 -0.5771146388984711 [134] [20] -4 hSpCas9 negative selection 519951
182585617 182585640 1 - 26472758 Raji viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 0.34277826077533224 [930] [273] 3 hSpCas9 negative selection 519952
182585846 182585869 1 + 26472758 Raji viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 -0.5566072115128273 [468] [73] -4 hSpCas9 negative selection 519953
182585723 182585746 1 + 26472758 Raji viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.47747362859846865 [488] [157] 4 hSpCas9 negative selection 519954
182585598 182585621 1 - 26472758 Raji viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 0.9919063179536636 [129] [59] 8 hSpCas9 negative selection 519955
182586754 182586777 1 - 26472758 Raji viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.09088609176267476 [256] [55] -1 hSpCas9 negative selection 519956
182586329 182586352 1 - 26472758 Raji viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 -0.026472211361191045 [78] [17] 0 hSpCas9 negative selection 519957
182586233 182586256 1 - 26472758 Raji viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 0.9025637434851014 [271] [117] 8 hSpCas9 negative selection 519958
182585776 182585799 1 - 26472758 Raji viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 0.13614252835502344 [297] [75] 1 hSpCas9 negative selection 519959
182585661 182585684 1 - 26472758 Raji viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 0.6646736176102012 [385] [141] 6 hSpCas9 negative selection 519960
182586302 182586325 1 - 26472758 K562 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 -1.1738070492434445 [301] [112] -6 hSpCas9 negative selection 711069
182585617 182585640 1 - 26472758 K562 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 -0.059378547078931865 [1363] [1104] 0 hSpCas9 negative selection 711070
182585846 182585869 1 + 26472758 K562 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 0.38824209662878495 [848] [937] 3 hSpCas9 negative selection 711071
182585723 182585746 1 + 26472758 K562 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.40824352957234145 [1105] [1238] 3 hSpCas9 negative selection 711072
182585598 182585621 1 - 26472758 K562 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 0.29409388669063663 [313] [324] 2 hSpCas9 negative selection 711073
182586754 182586777 1 - 26472758 K562 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 0.7298455548366887 [539] [755] 6 hSpCas9 negative selection 711074
182586329 182586352 1 - 26472758 K562 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 1.3783731843353109 [184] [405] 9 hSpCas9 negative selection 711075
182586233 182586256 1 - 26472758 K562 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 0.8279449962720842 [334] [501] 7 hSpCas9 negative selection 711076
182585776 182585799 1 - 26472758 K562 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 -0.5170691856338281 [355] [209] -3 hSpCas9 negative selection 711077
182585661 182585684 1 - 26472758 K562 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 0.20747714927831007 [711] [693] 1 hSpCas9 negative selection 711078
182575382 182575405 1 + 26627737 DLD1 viability AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -0.09815621223577675 [778] [206,228,243] -1 hSpCas9 negative selection 767913
182582222 182582245 1 - 26627737 DLD1 viability GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 -1.0475473903017172 [206] [10,64,20] -7 hSpCas9 negative selection 767914
182582243 182582266 1 - 26627737 DLD1 viability TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 0.9735717982171156 [484] [364,395,157] 8 hSpCas9 negative selection 767915
182584143 182584166 1 - 26627737 DLD1 viability TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 0.3791820753210965 [246] [104,106,90] 4 hSpCas9 negative selection 767916
182585525 182585548 1 - 26627737 DLD1 viability CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.004091273383148963 [911] [375,246,239] 0 hSpCas9 negative selection 767917
182585526 182585549 1 - 26627737 DLD1 viability TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 0.5142600359224716 [343] [66,227,166] 5 hSpCas9 negative selection 767918
182575382 182575405 1 + 26627737 GBM cells viability after 5 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -0.9568814022296717 [370] [102,101] -9 hSpCas9 negative selection 850228
182582222 182582245 1 - 26627737 GBM cells viability after 5 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 -0.3162542196828495 [165] [74,67] -5 hSpCas9 negative selection 850229
182582243 182582266 1 - 26627737 GBM cells viability after 5 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 0.04200083083278064 [210] [109,122] 0 hSpCas9 negative selection 850230
182584143 182584166 1 - 26627737 GBM cells viability after 5 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 0.36794626380525863 [176] [126,117] 5 hSpCas9 negative selection 850231
182585525 182585548 1 - 26627737 GBM cells viability after 5 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.3047680519991939 [393] [219,301] 5 hSpCas9 negative selection 850232
182585526 182585549 1 - 26627737 GBM cells viability after 5 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 0.7718019569823464 [82] [91,59] 9 hSpCas9 negative selection 850233
182575382 182575405 1 + 26627737 GBM cells viability after 13 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -0.16474136241418724 [370] [151,201] -2 hSpCas9 negative selection 932543
182582222 182582245 1 - 26627737 GBM cells viability after 13 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 -0.6513257131420033 [165] [58,55] -6 hSpCas9 negative selection 932544
182582243 182582266 1 - 26627737 GBM cells viability after 13 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 0.39926816335708815 [210] [193,115] 5 hSpCas9 negative selection 932545
182584143 182584166 1 - 26627737 GBM cells viability after 13 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 0.3499226540483704 [176] [160,90] 4 hSpCas9 negative selection 932546
182585525 182585548 1 - 26627737 GBM cells viability after 13 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.06332773250269919 [393] [272,182] 0 hSpCas9 negative selection 932547
182585526 182585549 1 - 26627737 GBM cells viability after 13 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 0.3728879188593033 [82] [70,47] 5 hSpCas9 negative selection 932548
182575382 182575405 1 + 26627737 GBM cells viability after 21 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -0.1483928874747107 [370] [196,167] -1 hSpCas9 negative selection 1014858
182582222 182582245 1 - 26627737 GBM cells viability after 21 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 -0.07657869609458667 [165] [84,85] 0 hSpCas9 negative selection 1014859
182582243 182582266 1 - 26627737 GBM cells viability after 21 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 0.3735611734279598 [210] [159,137] 4 hSpCas9 negative selection 1014860
182584143 182584166 1 - 26627737 GBM cells viability after 21 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 -0.13817774045643305 [176] [101,73] -1 hSpCas9 negative selection 1014861
182585525 182585548 1 - 26627737 GBM cells viability after 21 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 -0.035763848434038126 [393] [224,193] 0 hSpCas9 negative selection 1014862
182585526 182585549 1 - 26627737 GBM cells viability after 21 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 0.9525526546054561 [82] [80,92] 8 hSpCas9 negative selection 1014863
182575382 182575405 1 + 26627737 RPE1 viability after 9 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 0.007379786948220057 [660] [238,167] 0 hSpCas9 negative selection 1097173
182582222 182582245 1 - 26627737 RPE1 viability after 9 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 2.398139391081708 [94] [137,180] 9 hSpCas9 negative selection 1097174
182582243 182582266 1 - 26627737 RPE1 viability after 9 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 1.532910897843524 [448] [349,479] 8 hSpCas9 negative selection 1097175
182584143 182584166 1 - 26627737 RPE1 viability after 9 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 0.3043275073584404 [816] [331,294] 2 hSpCas9 negative selection 1097176
182585525 182585548 1 - 26627737 RPE1 viability after 9 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 -0.3246669917406262 [1610] [386,422] -2 hSpCas9 negative selection 1097177
182585526 182585549 1 - 26627737 RPE1 viability after 9 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -0.11474517695767894 [508] [106,198] -1 hSpCas9 negative selection 1097178
182575382 182575405 1 + 26627737 RPE1 viability after 12 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 0.11063397500075481 [660] [301,74] 0 hSpCas9 negative selection 1179488
182582222 182582245 1 - 26627737 RPE1 viability after 12 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 2.852950648884166 [94] [197,169] 9 hSpCas9 negative selection 1179489
182582243 182582266 1 - 26627737 RPE1 viability after 12 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 1.1925699870298296 [448] [265,285] 7 hSpCas9 negative selection 1179490
182584143 182584166 1 - 26627737 RPE1 viability after 12 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 0.45786497583403263 [816] [334,265] 3 hSpCas9 negative selection 1179491
182585525 182585548 1 - 26627737 RPE1 viability after 12 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.20262085606716873 [1610] [653,332] 1 hSpCas9 negative selection 1179492
182585526 182585549 1 - 26627737 RPE1 viability after 12 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -0.9508978521332595 [508] [61,79] -6 hSpCas9 negative selection 1179493
182575382 182575405 1 + 26627737 RPE1 viability after 15 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 0.07946349103306152 [660] [277,119] 0 hSpCas9 negative selection 1261803
182582222 182582245 1 - 26627737 RPE1 viability after 15 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 2.8134274489997315 [94] [165,210] 9 hSpCas9 negative selection 1261804
182582243 182582266 1 - 26627737 RPE1 viability after 15 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 0.6278341863934254 [448] [96,291] 4 hSpCas9 negative selection 1261805
182584143 182584166 1 - 26627737 RPE1 viability after 15 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 0.7194979579135514 [816] [433,328] 4 hSpCas9 negative selection 1261806
182585525 182585548 1 - 26627737 RPE1 viability after 15 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 -0.08955671529903575 [1610] [383,470] 0 hSpCas9 negative selection 1261807
182585526 182585549 1 - 26627737 RPE1 viability after 15 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -0.22861247451053612 [508] [44,197] -1 hSpCas9 negative selection 1261808
182575382 182575405 1 + 26627737 RPE1 viability after 18 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 0.24685514923343865 [660] [376,34] 1 hSpCas9 negative selection 1344118
182582222 182582245 1 - 26627737 RPE1 viability after 18 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 3.296549821024986 [94] [219,285] 9 hSpCas9 negative selection 1344119
182582243 182582266 1 - 26627737 RPE1 viability after 18 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 1.3547136491758112 [448] [262,359] 7 hSpCas9 negative selection 1344120
182584143 182584166 1 - 26627737 RPE1 viability after 18 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 -0.04494333660658886 [816] [292,128] 0 hSpCas9 negative selection 1344121
182585525 182585548 1 - 26627737 RPE1 viability after 18 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 -0.2431699432796326 [1610] [332,403] -1 hSpCas9 negative selection 1344122
182585526 182585549 1 - 26627737 RPE1 viability after 18 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -0.22367915452426923 [508] [106,128] -1 hSpCas9 negative selection 1344123
182575382 182575405 1 + 26627737 HeLa viability after 8 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -0.09473497276412701 [257] [93,173,48] -1 hSpCas9 negative selection 1426433
182582222 182582245 1 - 26627737 HeLa viability after 8 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 -0.36776339754453 [259] [155,62,60] -4 hSpCas9 negative selection 1426434
182582243 182582266 1 - 26627737 HeLa viability after 8 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 -0.9665985061353678 [966] [99,207,305] -7 hSpCas9 negative selection 1426435
182584143 182584166 1 - 26627737 HeLa viability after 8 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 -0.9841549688090173 [405] [237,22,42] -7 hSpCas9 negative selection 1426436
182585525 182585548 1 - 26627737 HeLa viability after 8 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 -0.11002657938108018 [895] [372,435,282] -1 hSpCas9 negative selection 1426437
182585526 182585549 1 - 26627737 HeLa viability after 8 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -2.053996475162626 [482] [112,37,16] -9 hSpCas9 negative selection 1426438
182575382 182575405 1 + 26627737 HeLa viability after 12 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -0.29463280465664254 [257] [47,177,23] -3 hSpCas9 negative selection 1508748
182582222 182582245 1 - 26627737 HeLa viability after 12 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 0.36837792588439155 [259] [201,109,108] 3 hSpCas9 negative selection 1508749
182582243 182582266 1 - 26627737 HeLa viability after 12 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 -1.2110733066505983 [966] [96,225,186] -8 hSpCas9 negative selection 1508750
182584143 182584166 1 - 26627737 HeLa viability after 12 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 -0.6857025954041164 [405] [48,97,164] -6 hSpCas9 negative selection 1508751
182585525 182585548 1 - 26627737 HeLa viability after 12 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 -0.4551405018795218 [895] [233,347,218] -4 hSpCas9 negative selection 1508752
182585526 182585549 1 - 26627737 HeLa viability after 12 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -1.5224473964222773 [482] [19,78,106] -8 hSpCas9 negative selection 1508753
182575382 182575405 1 + 26627737 HeLa viability after 15 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 0.3547584441261165 [257] [175,108,115] 3 hSpCas9 negative selection 1591063
182582222 182582245 1 - 26627737 HeLa viability after 15 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 -0.20149774621157635 [259] [79,119,74] -2 hSpCas9 negative selection 1591064
182582243 182582266 1 - 26627737 HeLa viability after 15 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 -0.4881777491995284 [966] [391,125,325] -4 hSpCas9 negative selection 1591065
182584143 182584166 1 - 26627737 HeLa viability after 15 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 -0.006015696622463616 [405] [130,152,213] 0 hSpCas9 negative selection 1591066
182585525 182585548 1 - 26627737 HeLa viability after 15 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 -0.08995182822688119 [895] [333,402,286] 0 hSpCas9 negative selection 1591067
182585526 182585549 1 - 26627737 HeLa viability after 15 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -2.2635416292857404 [482] [5,79,36] -9 hSpCas9 negative selection 1591068
182575382 182575405 1 + 26627737 HeLa viability after 18 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 0.3988393657598399 [257] [123,92,115] 3 hSpCas9 negative selection 1673378
182582222 182582245 1 - 26627737 HeLa viability after 18 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 -0.22397396432898287 [259] [51,97,74] -2 hSpCas9 negative selection 1673379
182582243 182582266 1 - 26627737 HeLa viability after 18 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 -0.45806193927389804 [966] [273,104,325] -4 hSpCas9 negative selection 1673380
182584143 182584166 1 - 26627737 HeLa viability after 18 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 0.016131739372773297 [405] [90,128,213] 0 hSpCas9 negative selection 1673381
182585525 182585548 1 - 26627737 HeLa viability after 18 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 -0.05416855666089848 [895] [230,345,286] 0 hSpCas9 negative selection 1673382
182585526 182585549 1 - 26627737 HeLa viability after 18 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -2.2070560871350207 [482] [4,68,36] -9 hSpCas9 negative selection 1673383
182575382 182575405 1 + 26627737 HCT116 viability after 6 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -2.0963773275961164 [624] [31,17] -8 hSpCas9 negative selection 1755693
182582222 182582245 1 - 26627737 HCT116 viability after 6 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 1.7738283284065313 [201] [18,157] 8 hSpCas9 negative selection 1755694
182582243 182582266 1 - 26627737 HCT116 viability after 6 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 0.22594139289496856 [763] [124,148] 1 hSpCas9 negative selection 1755695
182584143 182584166 1 - 26627737 HCT116 viability after 6 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 -0.3536892059877291 [484] [49,64] -2 hSpCas9 negative selection 1755696
182585525 182585548 1 - 26627737 HCT116 viability after 6 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 1.2074389910456635 [692] [491,118] 6 hSpCas9 negative selection 1755697
182585526 182585549 1 - 26627737 HCT116 viability after 6 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 2.478621596397031 [143] [4,192] 9 hSpCas9 negative selection 1755698
182575382 182575405 1 + 26627737 HCT116 viability after 8 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 0.0720608252946231 [225] [109,121,159] 0 hSpCas9 negative selection 1838008
182582222 182582245 1 - 26627737 HCT116 viability after 8 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 0.44482336695305946 [141] [116,120,81] 4 hSpCas9 negative selection 1838009
182582243 182582266 1 - 26627737 HCT116 viability after 8 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 0.29095948388091947 [406] [150,317,350] 3 hSpCas9 negative selection 1838010
182584143 182584166 1 - 26627737 HCT116 viability after 8 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 0.5969881660446029 [132] [163,99,69] 6 hSpCas9 negative selection 1838011
182585525 182585548 1 - 26627737 HCT116 viability after 8 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.5222149854554109 [365] [282,312,272] 5 hSpCas9 negative selection 1838012
182585526 182585549 1 - 26627737 HCT116 viability after 8 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -0.9574104853940759 [214] [59,60,61] -8 hSpCas9 negative selection 1838013
182575382 182575405 1 + 26627737 HCT116 viability after 9 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 0.4141501447000032 [624] [151,277] 3 hSpCas9 negative selection 1920323
182582222 182582245 1 - 26627737 HCT116 viability after 9 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 0.3393926354992436 [201] [22,103] 2 hSpCas9 negative selection 1920324
182582243 182582266 1 - 26627737 HCT116 viability after 9 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 -0.08659676193937116 [763] [376,45] 0 hSpCas9 negative selection 1920325
182584143 182584166 1 - 26627737 HCT116 viability after 9 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 -1.4026718792730255 [484] [10,78] -7 hSpCas9 negative selection 1920326
182585525 182585548 1 - 26627737 HCT116 viability after 9 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.9822369879460011 [692] [302,414] 6 hSpCas9 negative selection 1920327
182585526 182585549 1 - 26627737 HCT116 viability after 9 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 0.9940657883185509 [143] [70,80] 7 hSpCas9 negative selection 1920328
182575382 182575405 1 + 26627737 HCT116 viability after 12 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 0.06625680911355458 [225] [83,140,151] 0 hSpCas9 negative selection 2002638
182582222 182582245 1 - 26627737 HCT116 viability after 12 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 0.07411883938824215 [141] [82,107,44] 0 hSpCas9 negative selection 2002639
182582243 182582266 1 - 26627737 HCT116 viability after 12 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 -0.41519306782854193 [406] [159,191,129] -4 hSpCas9 negative selection 2002640
182584143 182584166 1 - 26627737 HCT116 viability after 12 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 0.22593400575190048 [132] [97,130,15] 2 hSpCas9 negative selection 2002641
182585525 182585548 1 - 26627737 HCT116 viability after 12 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.713337352433134 [365] [348,350,243] 6 hSpCas9 negative selection 2002642
182585526 182585549 1 - 26627737 HCT116 viability after 12 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -0.3310033945301536 [214] [32,111,129] -4 hSpCas9 negative selection 2002643
182575382 182575405 1 + 26627737 HCT116 viability after 15 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -0.3990174848660884 [225] [92,133,67] -4 hSpCas9 negative selection 2084953
182582222 182582245 1 - 26627737 HCT116 viability after 15 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 0.9620935549770862 [141] [168,79,227] 7 hSpCas9 negative selection 2084954
182582243 182582266 1 - 26627737 HCT116 viability after 15 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 0.19082039644476984 [406] [529,167,135] 2 hSpCas9 negative selection 2084955
182584143 182584166 1 - 26627737 HCT116 viability after 15 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 1.0799283451991304 [132] [260,114,120] 8 hSpCas9 negative selection 2084956
182585525 182585548 1 - 26627737 HCT116 viability after 15 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.6222461883567278 [365] [344,367,260] 5 hSpCas9 negative selection 2084957
182585526 182585549 1 - 26627737 HCT116 viability after 15 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -1.1989190444904279 [214] [57,60,42] -8 hSpCas9 negative selection 2084958
182575382 182575405 1 + 26627737 HCT116 viability after 18 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 0.29606813749732974 [225] [92,171,134] 2 hSpCas9 negative selection 2167268
182582222 182582245 1 - 26627737 HCT116 viability after 18 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 0.18496580793037032 [141] [103,76,51] 1 hSpCas9 negative selection 2167269
182582243 182582266 1 - 26627737 HCT116 viability after 18 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 0.23617732057578916 [406] [260,324,96] 2 hSpCas9 negative selection 2167270
182584143 182584166 1 - 26627737 HCT116 viability after 18 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 1.3241385457749004 [132] [177,170,131] 8 hSpCas9 negative selection 2167271
182585525 182585548 1 - 26627737 HCT116 viability after 18 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.9381804177506591 [365] [389,284,345] 7 hSpCas9 negative selection 2167272
182585526 182585549 1 - 26627737 HCT116 viability after 18 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -0.3164421764777231 [214] [149,33,68] -3 hSpCas9 negative selection 2167273
182586633 182586656 1 - 24336569 HL60 viability TTAATTTCCAGGAAGAGGAAGGG RNASEL ENSG00000135828 0.36240608085766013 [643] [1751] 3 hSpCas9 negative selection 2289838
182586638 182586661 1 - 24336569 HL60 viability CAATGTTAATTTCCAGGAAGAGG RNASEL ENSG00000135828 0.35584077692317423 [441] [1196] 3 hSpCas9 negative selection 2289839
182586644 182586667 1 - 24336569 HL60 viability TGGAGCCAATGTTAATTTCCAGG RNASEL ENSG00000135828 -0.412178661425353 [946] [1505] -4 hSpCas9 negative selection 2289840
182586662 182586685 1 + 24336569 HL60 viability CTCCACCTTCCAGCAATTGCTGG RNASEL ENSG00000135828 0.03210742507596548 [640] [1386] 0 hSpCas9 negative selection 2289841
182586667 182586690 1 - 24336569 HL60 viability CTGGTCCAGCAATTGCTGGAAGG RNASEL ENSG00000135828 1.247297376084887 [336] [1692] 8 hSpCas9 negative selection 2289842
182586737 182586760 1 - 24336569 HL60 viability CAGCGGTAGAAGGGCTGCAGTGG RNASEL ENSG00000135828 0.8065237813032275 [926] [3430] 6 hSpCas9 negative selection 2289843
182586746 182586769 1 - 24336569 HL60 viability CACGTCCTCCAGCGGTAGAAGGG RNASEL ENSG00000135828 0.666748198712044 [689] [2317] 5 hSpCas9 negative selection 2289844
182586754 182586777 1 - 24336569 HL60 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.7702367477693025 [838] [1040] -6 hSpCas9 negative selection 2289845
182586759 182586782 1 + 24336569 HL60 viability GGAGGACGTGGGTCCCTCCTGGG RNASEL ENSG00000135828 1.4105254143137957 [234] [1321] 8 hSpCas9 negative selection 2289846
182586794 182586817 1 - 24336569 HL60 viability ATTTACCGTCATGGAGAGCAGGG RNASEL ENSG00000135828 -0.3878681346109365 [958] [1550] -3 hSpCas9 negative selection 2289847
182586633 182586656 1 - 24336569 KBM7 viability TTAATTTCCAGGAAGAGGAAGGG RNASEL ENSG00000135828 0.7169016662033021 [471] [2115] 6 hSpCas9 negative selection 2357015
182586638 182586661 1 - 24336569 KBM7 viability CAATGTTAATTTCCAGGAAGAGG RNASEL ENSG00000135828 1.371010929511705 [200] [1417] 9 hSpCas9 negative selection 2357016
182586644 182586667 1 - 24336569 KBM7 viability TGGAGCCAATGTTAATTTCCAGG RNASEL ENSG00000135828 0.7186904659692158 [482] [2167] 6 hSpCas9 negative selection 2357017
182586662 182586685 1 + 24336569 KBM7 viability CTCCACCTTCCAGCAATTGCTGG RNASEL ENSG00000135828 0.425814487071549 [365] [1340] 4 hSpCas9 negative selection 2357018
182586667 182586690 1 - 24336569 KBM7 viability CTGGTCCAGCAATTGCTGGAAGG RNASEL ENSG00000135828 0.5235659407789325 [403] [1583] 5 hSpCas9 negative selection 2357019
182586737 182586760 1 - 24336569 KBM7 viability CAGCGGTAGAAGGGCTGCAGTGG RNASEL ENSG00000135828 0.27915447500636725 [848] [2809] 2 hSpCas9 negative selection 2357020
182586746 182586769 1 - 24336569 KBM7 viability CACGTCCTCCAGCGGTAGAAGGG RNASEL ENSG00000135828 0.8062618552022895 [550] [2627] 7 hSpCas9 negative selection 2357021
182586754 182586777 1 - 24336569 KBM7 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 0.6491359579396532 [255] [1094] 6 hSpCas9 negative selection 2357022
182586759 182586782 1 + 24336569 KBM7 viability GGAGGACGTGGGTCCCTCCTGGG RNASEL ENSG00000135828 0.2999778088850391 [379] [1275] 2 hSpCas9 negative selection 2357023
182586794 182586817 1 - 24336569 KBM7 viability ATTTACCGTCATGGAGAGCAGGG RNASEL ENSG00000135828 0.39244191442904364 [785] [2813] 3 hSpCas9 negative selection 2357024
182585852 182585875 1 - 27013184 SW480 treatment with recombinant TRAIL TTATGACCATTCCCTTGTGAAGG RNASEL ENSG00000135828 -1.2011936574451454 [1,20] [1,1] -5 hSpCas9 positive selection 2960312
182585877 182585900 1 - 27013184 SW480 treatment with recombinant TRAIL ATCTTGTTATGACAGCGAGGCGG RNASEL ENSG00000135828 2.844795263639932 [95,185] [517,291] 9 hSpCas9 positive selection 2960313
182585901 182585924 1 - 27013184 SW480 treatment with recombinant TRAIL GTGGAGCCAGTACAGATTGTGGG RNASEL ENSG00000135828 2.3666528099203976 [74,98] [156,239] 8 hSpCas9 positive selection 2960314
182586128 182586151 1 - 27013184 SW480 treatment with recombinant TRAIL GGCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 -0.3621966905857352 [848,924] [268,335] -2 hSpCas9 positive selection 2960315
182586149 182586172 1 - 27013184 SW480 treatment with recombinant TRAIL CTCTGACGATAGTGATGTGGAGG RNASEL ENSG00000135828 1.494731884073365 [38,80] [99,28] 7 hSpCas9 positive selection 2960316
182586202 182586225 1 - 27013184 SW480 treatment with recombinant TRAIL GTAAACGCCTGTGACAATATGGG RNASEL ENSG00000135828 -1.3584911426932251 [125,89] [29,1] -6 hSpCas9 positive selection 2960317
182586271 182586294 1 - 27013184 SW480 treatment with recombinant TRAIL CTCATGGACGCTGCTGAAAAAGG RNASEL ENSG00000135828 0.43959380222791977 [77,151] [78,45] 2 hSpCas9 positive selection 2960318
182586738 182586761 1 + 27013184 SW480 treatment with recombinant TRAIL CACTGCAGCCCTTCTACCGCTGG RNASEL ENSG00000135828 -2.234801897459454 [738,774] [34,117] -8 hSpCas9 positive selection 2960319
182586741 182586764 1 + 27013184 SW480 treatment with recombinant TRAIL TGCAGCCCTTCTACCGCTGGAGG RNASEL ENSG00000135828 1.1518536478210564 [270,564] [443,308] 5 hSpCas9 positive selection 2960320
182586747 182586770 1 + 27013184 SW480 treatment with recombinant TRAIL CCTTCTACCGCTGGAGGACGTGG RNASEL ENSG00000135828 0.14378635918167687 [194,124] [130,1] 0 hSpCas9 positive selection 2960321
182586748 182586771 1 + 27013184 SW480 treatment with recombinant TRAIL CTTCTACCGCTGGAGGACGTGGG RNASEL ENSG00000135828 -0.9322474993740801 [813,905] [129,283] -4 hSpCas9 positive selection 2960322
182586789 182586812 1 + 27013184 SW480 treatment with recombinant TRAIL ATGATCCCTGCTCTCCATGACGG RNASEL ENSG00000135828 1.0982877944562033 [106,183] [115,152] 5 hSpCas9 positive selection 2960323
182585590 182585613 1 + 27013184 SW480 treatment with recombinant TRAIL GAGACTTCCCGCTGTGCACGTGG RNASEL ENSG00000135828 0.09688140560779379 [880,946] [242,672] 0 hSpCas9 positive selection 2960324
182585720 182585743 1 + 27013184 SW480 treatment with recombinant TRAIL ACTTGAGTTTGCCAATCATAGGG RNASEL ENSG00000135828 -4.252339705200807 [301,289] [2,11] -9 hSpCas9 positive selection 2960325
182586494 182586517 1 + 27013184 SW480 treatment with recombinant TRAIL CGCTCCCCGCAATCGCTGCGAGG RNASEL ENSG00000135828 0.26623051170672607 [822,1022] [291,733] 1 hSpCas9 positive selection 2960326
182586395 182586418 1 - 27013184 SW480 treatment with recombinant TRAIL GGAAGCCGCTGTGTATGGTAAGG RNASEL ENSG00000135828 0.8410631653624137 [185,316] [146,250] 4 hSpCas9 positive selection 2960327
182586498 182586521 1 - 27013184 SW480 treatment with recombinant TRAIL TTATCCTCGCAGCGATTGCGGGG RNASEL ENSG00000135828 -1.6795349909854589 [288,534] [39,73] -6 hSpCas9 positive selection 2960328
182586499 182586522 1 - 27013184 SW480 treatment with recombinant TRAIL TTTATCCTCGCAGCGATTGCGGG RNASEL ENSG00000135828 -0.091251973772978 [61,67] [5,54] 0 hSpCas9 positive selection 2960329
182586500 182586523 1 - 27013184 SW480 treatment with recombinant TRAIL TTTTATCCTCGCAGCGATTGCGG RNASEL ENSG00000135828 0.12697561720497286 [281,325] [72,240] 0 hSpCas9 positive selection 2960330
182586594 182586617 1 - 27013184 SW480 treatment with recombinant TRAIL ATAACGCAGTACAAATGAGCAGG RNASEL ENSG00000135828 0.8300969910716477 [205,187] [107,213] 4 hSpCas9 positive selection 2960331
182586686 182586709 1 - 27013184 SW480 treatment with recombinant TRAIL TCAAAACGAAGATGTTGACCTGG RNASEL ENSG00000135828 -3.977350747868554 [72,72] [1,1] -9 hSpCas9 positive selection 2960332
182586737 182586760 1 - 27013184 SW480 treatment with recombinant TRAIL CAGCGGTAGAAGGGCTGCAGTGG RNASEL ENSG00000135828 1.2242027626800516 [43,5] [16,40] 6 hSpCas9 positive selection 2960333
182586746 182586769 1 - 27013184 SW480 treatment with recombinant TRAIL CACGTCCTCCAGCGGTAGAAGGG RNASEL ENSG00000135828 1.2336981420945987 [1186,632] [907,1005] 6 hSpCas9 positive selection 2960334
182586747 182586770 1 - 27013184 SW480 treatment with recombinant TRAIL CCACGTCCTCCAGCGGTAGAAGG RNASEL ENSG00000135828 3.18846830191978 [79,83] [396,214] 9 hSpCas9 positive selection 2960335
182586794 182586817 1 - 27013184 SW480 treatment with recombinant TRAIL ATTTACCGTCATGGAGAGCAGGG RNASEL ENSG00000135828 -1.6472658190016967 [409,440] [24,105] -6 hSpCas9 positive selection 2960336
182586795 182586818 1 - 27013184 SW480 treatment with recombinant TRAIL CATTTACCGTCATGGAGAGCAGG RNASEL ENSG00000135828 -1.3286968605632667 [370,349] [71,47] -6 hSpCas9 positive selection 2960337
182586803 182586826 1 - 27013184 SW480 treatment with recombinant TRAIL GCAGGTGGCATTTACCGTCATGG RNASEL ENSG00000135828 -0.026633550464209732 [265,232] [95,120] 0 hSpCas9 positive selection 2960338
182585542 182585565 1 - 27013184 SW480 treatment with recombinant TRAIL AGTCACTTGGTGACATTCTATGG RNASEL ENSG00000135828 -1.7195833087543329 [318,294] [60,10] -7 hSpCas9 positive selection 2960339
182585663 182585686 1 - 27013184 SW480 treatment with recombinant TRAIL TTCAGAAGGAGGCATCTACCTGG RNASEL ENSG00000135828 -1.4817646110337184 [8,25] [2,1] -6 hSpCas9 positive selection 2960340
182585731 182585754 1 - 27013184 SW480 treatment with recombinant TRAIL AGAATATACCGCCCTATGATTGG RNASEL ENSG00000135828 0.6928258334525021 [257,310] [98,335] 3 hSpCas9 positive selection 2960341
182586090 182586113 1 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity TCAATGTGAGGGGAGAAAGAGGG RNASEL ENSG00000135828 0.08475975951499648 [4,5] [5,3] 1 hSpCas9 positive selection 3017076
182585724 182585747 1 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.09656692582271278 [3,4] [4,3] 2 hSpCas9 positive selection 3017077
182586498 182586521 1 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity TTATCCTCGCAGCGATTGCGGGG RNASEL ENSG00000135828 0.15371737712508077 [3,3] [1,4] 3 hSpCas9 positive selection 3017078
182586391 182586414 1 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity TTTGACCTTACCATACACAGCGG RNASEL ENSG00000135828 0.27607465081496546 [4,4] [5,3] 6 hSpCas9 positive selection 3017079
182586090 182586113 1 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity TCAATGTGAGGGGAGAAAGAGGG RNASEL ENSG00000135828 0.4613579487981301 [4,4] [4,4] 7 hSpCas9 positive selection 3084934
182585724 182585747 1 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.5436457364096596 [3,3] [4,3] 8 hSpCas9 positive selection 3084935
182586498 182586521 1 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity TTATCCTCGCAGCGATTGCGGGG RNASEL ENSG00000135828 -0.4124439585711293 [3,3] [2,0] -6 hSpCas9 positive selection 3084936
182586391 182586414 1 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity TTTGACCTTACCATACACAGCGG RNASEL ENSG00000135828 0.19686709680668962 [4,4] [4,2] 3 hSpCas9 positive selection 3084937
182582116 182582139 - 24336571 A375 resistance to PLX after 7 days ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.16610034817397934 [29,27] [32,31] 5 hSpCas9 positive selection 3141151
182582153 182582176 - 24336571 A375 resistance to PLX after 7 days GGTTCAACTTTCTCCAGATGAGG RNASEL ENSG00000135828 -0.026401957614482052 [5,5] [5,5] 0 hSpCas9 positive selection 3141152
182582058 182582081 - 24336571 A375 resistance to PLX after 7 days GTCATCCCTTCTTTTGGACTTGG RNASEL ENSG00000135828 -0.24024965462735812 [16,13] [12,12] -7 hSpCas9 positive selection 3141154
182584125 182584148 + 24336571 A375 resistance to PLX after 7 days TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.2245068741520494 [8,8] [10,8] 6 hSpCas9 positive selection 3141155
182582116 182582139 - 24336571 A375 resistance to PLX after 14 days ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.2802465472523823 [30,33] [16,19] 3 hSpCas9 positive selection 3198944
182582153 182582176 - 24336571 A375 resistance to PLX after 14 days GGTTCAACTTTCTCCAGATGAGG RNASEL ENSG00000135828 0.4655281547916984 [5,5] [3,2] 4 hSpCas9 positive selection 3198945
182582058 182582081 - 24336571 A375 resistance to PLX after 14 days GTCATCCCTTCTTTTGGACTTGG RNASEL ENSG00000135828 -0.45697665535969967 [17,14] [4,5] -5 hSpCas9 positive selection 3198947
182584125 182584148 + 24336571 A375 resistance to PLX after 14 days TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -1.0302946868357472 [11,11] [2,1] -9 hSpCas9 positive selection 3198948
182582116 182582139 - 24336571 A375 viability after 7 days ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.15284582729537144 [27] [29,27] 2 hSpCas9 negative selection 3256737
182582153 182582176 - 24336571 A375 viability after 7 days GGTTCAACTTTCTCCAGATGAGG RNASEL ENSG00000135828 0.18655496856197584 [5] [5,5] 3 hSpCas9 negative selection 3256738
182582058 182582081 - 24336571 A375 viability after 7 days GTCATCCCTTCTTTTGGACTTGG RNASEL ENSG00000135828 0.09217803236214428 [14] [16,13] 1 hSpCas9 negative selection 3256740
182584125 182584148 + 24336571 A375 viability after 7 days TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.4329440301844759 [11] [8,8] -6 hSpCas9 negative selection 3256741
182582116 182582139 - 24336571 A375 viability after 14 days ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.3232990522742658 [27] [30,33] 4 hSpCas9 negative selection 3314530
182582153 182582176 - 24336571 A375 viability after 14 days GGTTCAACTTTCTCCAGATGAGG RNASEL ENSG00000135828 0.1821120699837271 [5] [5,5] 2 hSpCas9 negative selection 3314531
182582058 182582081 - 24336571 A375 viability after 14 days GTCATCCCTTCTTTTGGACTTGG RNASEL ENSG00000135828 0.22836928608681017 [14] [17,14] 3 hSpCas9 negative selection 3314533
182584125 182584148 + 24336571 A375 viability after 14 days TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.03267145915550179 [11] [11,11] 0 hSpCas9 negative selection 3314534
182582081 182582104 1 - 27383988 293T resistance to West Nile virus (flavivirus) GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 -0.7979562240553546 [265,265] [0,0] -5 hSpCas9 positive selection 3390018
182584125 182584148 1 + 27383988 293T resistance to West Nile virus (flavivirus) TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.8407058715146917 [273,273] [0,0] -6 hSpCas9 positive selection 3390019
182576308 182576331 1 + 27383988 293T resistance to West Nile virus (flavivirus) GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 1.3746831620839939 [58,58] [0,0] 6 hSpCas9 positive selection 3390020
182586090 182586113 1 - 26780180 HT29 viability (Avana library 4 designs) TCAATGTGAGGGGAGAAAGAGGG RNASEL ENSG00000135828 0.56295980426846 [] [] 2 hSpCas9 negative selection 3455447
182585723 182585746 1 + 26780180 HT29 viability (Avana library 4 designs) TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.755051489261321 [] [] 3 hSpCas9 negative selection 3455448
182586498 182586521 1 - 26780180 HT29 viability (Avana library 4 designs) TTATCCTCGCAGCGATTGCGGGG RNASEL ENSG00000135828 0.674128797247375 [] [] 2 hSpCas9 negative selection 3455449
182586390 182586413 1 + 26780180 HT29 viability (Avana library 4 designs) TTTGACCTTACCATACACAGCGG RNASEL ENSG00000135828 0.437613528447876 [] [] 1 hSpCas9 negative selection 3455450
182586498 182586521 1 - 26780180 A375 viability (Avana lentiCRISPRv2) TTATCCTCGCAGCGATTGCGGGG RNASEL ENSG00000135828 3.57326234718105 [] [] 5 hSpCas9 negative selection 3553440
182585723 182585746 1 + 26780180 A375 viability (Avana lentiCRISPRv2) TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 -0.845770764441694 [] [] -1 hSpCas9 negative selection 3553441
182586390 182586413 1 + 26780180 A375 viability (Avana lentiCRISPRv2) TTTGACCTTACCATACACAGCGG RNASEL ENSG00000135828 -7.29710506046325 [] [] -6 hSpCas9 negative selection 3553442
182586090 182586113 1 - 26780180 A375 viability (Avana lentiCRISPRv2) TCAATGTGAGGGGAGAAAGAGGG RNASEL ENSG00000135828 -1.27506218397153 [] [] -1 hSpCas9 negative selection 3553443
182585841 182585864 1 + 26780180 A375 viability (Avana lentiCRISPRv2) AGAGAGAAGAACCTTCACAAGGG RNASEL ENSG00000135828 -6.13061506114413 [] [] -6 hSpCas9 negative selection 3553444
182586104 182586127 1 + 26780180 A375 viability (Avana lentiCRISPRv2) TCACATTGACATCAGCCCCATGG RNASEL ENSG00000135828 -1.07325839719332 [] [] -1 hSpCas9 negative selection 3553445
182586498 182586521 1 - 26780180 A375 viability (Avana lentiGuide) TTATCCTCGCAGCGATTGCGGGG RNASEL ENSG00000135828 1.60121760728975 [] [] 1 hSpCas9 negative selection 3662099
182585723 182585746 1 + 26780180 A375 viability (Avana lentiGuide) TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 1.93033316663812 [] [] 2 hSpCas9 negative selection 3662100
182586390 182586413 1 + 26780180 A375 viability (Avana lentiGuide) TTTGACCTTACCATACACAGCGG RNASEL ENSG00000135828 4.27253706097052 [] [] 4 hSpCas9 negative selection 3662101
182586090 182586113 1 - 26780180 A375 viability (Avana lentiGuide) TCAATGTGAGGGGAGAAAGAGGG RNASEL ENSG00000135828 -2.79275025992486 [] [] -5 hSpCas9 negative selection 3662102
182585841 182585864 1 + 26780180 A375 viability (Avana lentiGuide) AGAGAGAAGAACCTTCACAAGGG RNASEL ENSG00000135828 2.34471729962676 [] [] 2 hSpCas9 negative selection 3662103
182586104 182586127 1 + 26780180 A375 viability (Avana lentiGuide) TCACATTGACATCAGCCCCATGG RNASEL ENSG00000135828 3.16803121599211 [] [] 3 hSpCas9 negative selection 3662104
182586498 182586521 1 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TTATCCTCGCAGCGATTGCGGGG RNASEL ENSG00000135828 0.08195214050640519 [5] [5,5] 2 hSpCas9 positive selection 3770706
182585723 182585746 1 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 -0.20112452692295024 [5] [4,3] -3 hSpCas9 positive selection 3770707
182586390 182586413 1 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TTTGACCTTACCATACACAGCGG RNASEL ENSG00000135828 -0.5597132970477885 [5] [3,3] -7 hSpCas9 positive selection 3770708
182586090 182586113 1 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TCAATGTGAGGGGAGAAAGAGGG RNASEL ENSG00000135828 0.0316871885031835 [6] [6,5] 0 hSpCas9 positive selection 3770709
182585841 182585864 1 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) AGAGAGAAGAACCTTCACAAGGG RNASEL ENSG00000135828 -0.5833217348831268 [6] [4,3] -7 hSpCas9 positive selection 3770710
182586104 182586127 1 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TCACATTGACATCAGCCCCATGG RNASEL ENSG00000135828 -0.15497265742277724 [4] [3,4] -3 hSpCas9 positive selection 3770711
182586498 182586521 1 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TTATCCTCGCAGCGATTGCGGGG RNASEL ENSG00000135828 -0.31894478123797726 [5] [2,4] -4 hSpCas9 positive selection 3879313
182585723 182585746 1 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 -0.08950527491697445 [5] [5,3] -1 hSpCas9 positive selection 3879314
182586390 182586413 1 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TTTGACCTTACCATACACAGCGG RNASEL ENSG00000135828 0.017420146808655335 [6] [5,4] 0 hSpCas9 positive selection 3879315
182586090 182586113 1 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TCAATGTGAGGGGAGAAAGAGGG RNASEL ENSG00000135828 0.32447214216023024 [6] [6,6] 8 hSpCas9 positive selection 3879316
182585841 182585864 1 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) AGAGAGAAGAACCTTCACAAGGG RNASEL ENSG00000135828 0.1197957636216401 [5] [4,5] 2 hSpCas9 positive selection 3879317
182586104 182586127 1 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TCACATTGACATCAGCCCCATGG RNASEL ENSG00000135828 -0.01034084439817734 [5] [5,3] 0 hSpCas9 positive selection 3879318
182582116 182582139 1 - 26780180 A375 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.973068706566763 [] [] 4 hSpCas9 negative selection 3989432
182581335 182581358 1 + 26780180 A375 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.716828263655451 [] [] 2 hSpCas9 negative selection 3989433
182576308 182576331 1 + 26780180 A375 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.679984461793906 [] [] 2 hSpCas9 negative selection 3989434
182582081 182582104 1 - 26780180 A375 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 2.00932527814629 [] [] 9 hSpCas9 negative selection 3989435
182581339 182581362 1 - 26780180 A375 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.690098421289368 [] [] 2 hSpCas9 negative selection 3989436
182584125 182584148 1 + 26780180 A375 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 1.16353121600172 [] [] 6 hSpCas9 negative selection 3989437
182582116 182582139 1 - 26780180 HT29 viability (GeCKOv2 library) ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 1.00962206975106 [] [] 4 hSpCas9 negative selection 4097398
182581335 182581358 1 + 26780180 HT29 viability (GeCKOv2 library) CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.292823640410042 [] [] 0 hSpCas9 negative selection 4097399
182576308 182576331 1 + 26780180 HT29 viability (GeCKOv2 library) GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 1.14196634885075 [] [] 5 hSpCas9 negative selection 4097400
182582081 182582104 1 - 26780180 HT29 viability (GeCKOv2 library) GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 1.922226913302 [] [] 9 hSpCas9 negative selection 4097401
182581339 182581362 1 - 26780180 HT29 viability (GeCKOv2 library) TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.715200099535156 [] [] 2 hSpCas9 negative selection 4097402
182584125 182584148 1 + 26780180 HT29 viability (GeCKOv2 library) TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 1.61420712555843 [] [] 8 hSpCas9 negative selection 4097403
182582116 182582139 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.26320747429109287 [4] [3,4] 6 hSpCas9 positive selection 4166660
182582153 182582176 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GGTTCAACTTTCTCCAGATGAGG RNASEL ENSG00000135828 0.01927994981504777 [2] [1,1] 0 hSpCas9 positive selection 4166661
182582058 182582081 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GTCATCCCTTCTTTTGGACTTGG RNASEL ENSG00000135828 0.1570833219087152 [3] [2,2] 4 hSpCas9 positive selection 4166663
182584125 182584148 1 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.38074644527396256 [2] [1,0] -7 hSpCas9 positive selection 4166664
182582116 182582139 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.8045293699151981 [4] [0,4,3,3] 5 hSpCas9 positive selection 4230682
182582153 182582176 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GGTTCAACTTTCTCCAGATGAGG RNASEL ENSG00000135828 -0.1468725043317608 [1] [0,0,0,0] -2 hSpCas9 positive selection 4230683
182582058 182582081 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GTCATCCCTTCTTTTGGACTTGG RNASEL ENSG00000135828 0.3796663209892045 [3] [4,2,2,0] 3 hSpCas9 positive selection 4230685
182584125 182584148 1 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.0010619517514688648 [4] [0,4,2,0] 0 hSpCas9 positive selection 4230686
182581339 182581362 1 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.3477154668811675 [3] [2,1] -6 hSpCas9 positive selection 4295070
182581335 182581358 1 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.5459147726484702 [1] [0,0] -8 hSpCas9 positive selection 4295071
182582116 182582139 1 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.2850461917719424 [4] [4,3] 6 hSpCas9 positive selection 4295072
182582081 182582104 1 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 -0.4667256384520425 [3] [2,0] -7 hSpCas9 positive selection 4359324
182584125 182584148 1 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.34358833526671445 [3] [3,3] 7 hSpCas9 positive selection 4359325
182576308 182576331 1 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 -0.6682564277428553 [1] [0,0] -9 hSpCas9 positive selection 4359326
182586128 182586150 1 - 27760321 OCIAML3 viability GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 0.45956184998000876 [617,607] [650,673] 5 hSpCas9 negative selection 4434948
182586156 182586178 1 + 27760321 OCIAML3 viability ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 -0.760531211611633 [556,434] [216,240] -6 hSpCas9 negative selection 4434949
182586203 182586225 1 - 27760321 OCIAML3 viability GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 0.33037173941348147 [288,255] [204,348] 4 hSpCas9 negative selection 4434950
182586508 182586530 1 + 27760321 OCIAML3 viability GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 0.4660746796609795 [510,389] [488,474] 5 hSpCas9 negative selection 4434951
182586602 182586624 1 + 27760321 OCIAML3 viability TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 -0.6431996412954776 [246,224] [108,129] -6 hSpCas9 negative selection 4434952
182586128 182586150 1 - 27760321 OCIAML2 viability GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 0.6715271852342266 [617,607] [576,1074] 8 hSpCas9 negative selection 4518411
182586156 182586178 1 + 27760321 OCIAML2 viability ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 -0.19803430761978782 [556,434] [330,368] -2 hSpCas9 negative selection 4518412
182586203 182586225 1 - 27760321 OCIAML2 viability GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 -0.1716096645265841 [288,255] [200,187] -2 hSpCas9 negative selection 4518413
182586508 182586530 1 + 27760321 OCIAML2 viability GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 0.19532704052362293 [510,389] [448,367] 2 hSpCas9 negative selection 4518414
182586602 182586624 1 + 27760321 OCIAML2 viability TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 0.3096269301442588 [246,224] [185,302] 4 hSpCas9 negative selection 4518415
182586128 182586150 1 - 27760321 MV411 viability GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 0.2923795413194768 [617,607] [367,689] 2 hSpCas9 negative selection 4601874
182586156 182586178 1 + 27760321 MV411 viability ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 -0.09424508120898073 [556,434] [212,441] 0 hSpCas9 negative selection 4601875
182586203 182586225 1 - 27760321 MV411 viability GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 -0.9832572642727805 [288,255] [99,76] -6 hSpCas9 negative selection 4601876
182586508 182586530 1 + 27760321 MV411 viability GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 1.1851639528782678 [510,389] [866,375] 8 hSpCas9 negative selection 4601877
182586602 182586624 1 + 27760321 MV411 viability TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 -1.6863943734454967 [246,224] [1,117] -8 hSpCas9 negative selection 4601878
182586128 182586150 1 - 27760321 HL60 viability GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 0.8788250675614908 [617,607] [946,897] 8 hSpCas9 negative selection 4685337
182586156 182586178 1 + 27760321 HL60 viability ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 0.3520043635466524 [556,434] [566,456] 4 hSpCas9 negative selection 4685338
182586203 182586225 1 - 27760321 HL60 viability GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 -0.17308199204897967 [288,255] [216,175] -2 hSpCas9 negative selection 4685339
182586508 182586530 1 + 27760321 HL60 viability GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 -0.47698515032821587 [510,389] [240,284] -5 hSpCas9 negative selection 4685340
182586602 182586624 1 + 27760321 HL60 viability TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 1.3278377145191194 [246,224] [389,582] 9 hSpCas9 negative selection 4685341
182586128 182586150 1 - 27760321 HT1080 viability GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 0.4206345968300508 [607,474] [230,351] 2 hSpCas9 negative selection 4768800
182586156 182586178 1 + 27760321 HT1080 viability ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 1.5447099751491284 [434,339] [479,417] 8 hSpCas9 negative selection 4768801
182586203 182586225 1 - 27760321 HT1080 viability GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 1.0217009502931906 [255,199] [245,116] 5 hSpCas9 negative selection 4768802
182586508 182586530 1 + 27760321 HT1080 viability GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 0.7487934996522939 [389,304] [140,332] 4 hSpCas9 negative selection 4768803
182586602 182586624 1 + 27760321 HT1080 viability TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 0.963560621032667 [224,175] [87,229] 5 hSpCas9 negative selection 4768804
182586128 182586150 1 - 27760321 HT29 viability after 7 days GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 0.27189033332137413 [607,474] [804,880,829] 4 hSpCas9 negative selection 4852263
182586156 182586178 1 + 27760321 HT29 viability after 7 days ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 -0.13714742857586112 [434,339] [350,475,514] -2 hSpCas9 negative selection 4852264
182586203 182586225 1 - 27760321 HT29 viability after 7 days GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 -0.12618471799563813 [255,199] [264,241,296] -2 hSpCas9 negative selection 4852265
182586508 182586530 1 + 27760321 HT29 viability after 7 days GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 0.388043586426914 [389,304] [717,520,534] 6 hSpCas9 negative selection 4852266
182586602 182586624 1 + 27760321 HT29 viability after 7 days TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 -1.6702474178993283 [224,175] [57,48,130] -9 hSpCas9 negative selection 4852267
182586128 182586150 1 - 27760321 HT29 viability after 25 days GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 0.05258011615252833 [607,474] [517,680,743] 0 hSpCas9 negative selection 4935726
182586156 182586178 1 + 27760321 HT29 viability after 25 days ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 0.38245791243012056 [434,339] [619,482,630] 4 hSpCas9 negative selection 4935727
182586203 182586225 1 - 27760321 HT29 viability after 25 days GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 0.30091974614601563 [255,199] [310,306,347] 3 hSpCas9 negative selection 4935728
182586508 182586530 1 + 27760321 HT29 viability after 25 days GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 0.4341406879407196 [389,304] [486,667,447] 5 hSpCas9 negative selection 4935729
182586602 182586624 1 + 27760321 HT29 viability after 25 days TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 -1.3350739614934328 [224,175] [82,71,120] -7 hSpCas9 negative selection 4935730
182586128 182586150 1 - 27760321 HT29 viability after 22 days GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 0.27336358065610467 [607,474] [460,735,1083] 3 hSpCas9 negative selection 5019189
182586156 182586178 1 + 27760321 HT29 viability after 22 days ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 0.6966294637173861 [434,339] [988,680,498] 7 hSpCas9 negative selection 5019190
182586203 182586225 1 - 27760321 HT29 viability after 22 days GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 0.8311215270499217 [255,199] [444,335,627] 8 hSpCas9 negative selection 5019191
182586508 182586530 1 + 27760321 HT29 viability after 22 days GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 0.21650360224823534 [389,304] [464,627,305] 2 hSpCas9 negative selection 5019192
182586602 182586624 1 + 27760321 HT29 viability after 22 days TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 -0.49812892248764784 [224,175] [112,88,292] -4 hSpCas9 negative selection 5019193
182586128 182586150 1 - 27760321 HT29 viability after 19 days GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 0.26595402563156334 [607,474] [792,762,684] 2 hSpCas9 negative selection 5102652
182586156 182586178 1 + 27760321 HT29 viability after 19 days ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 0.8737637763291969 [434,339] [828,750,855] 8 hSpCas9 negative selection 5102653
182586203 182586225 1 - 27760321 HT29 viability after 19 days GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 0.35111681874050976 [255,199] [386,300,315] 3 hSpCas9 negative selection 5102654
182586508 182586530 1 + 27760321 HT29 viability after 19 days GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 0.66194350445917 [389,304] [899,743,283] 6 hSpCas9 negative selection 5102655
182586602 182586624 1 + 27760321 HT29 viability after 19 days TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 -0.5729131326851921 [224,175] [96,139,216] -5 hSpCas9 negative selection 5102656
182586128 182586150 1 - 27760321 HT29 viability after 16 days GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 0.18005640288415325 [607,474] [714,640,706] 2 hSpCas9 negative selection 5186115
182586156 182586178 1 + 27760321 HT29 viability after 16 days ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 0.4710199541635906 [434,339] [626,611,565] 5 hSpCas9 negative selection 5186116
182586203 182586225 1 - 27760321 HT29 viability after 16 days GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 0.020170552076381743 [255,199] [232,243,296] 0 hSpCas9 negative selection 5186117
182586508 182586530 1 + 27760321 HT29 viability after 16 days GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 0.8070160052411989 [389,304] [713,908,414] 8 hSpCas9 negative selection 5186118
182586602 182586624 1 + 27760321 HT29 viability after 16 days TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 -0.6708964727856802 [224,175] [133,143,143] -6 hSpCas9 negative selection 5186119
182586128 182586150 1 - 27760321 HT29 viability after 13 days GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 0.1594317150571284 [607,474] [630,806,668] 2 hSpCas9 negative selection 5269578
182586156 182586178 1 + 27760321 HT29 viability after 13 days ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 0.2834756096821475 [434,339] [602,433,600] 3 hSpCas9 negative selection 5269579
182586203 182586225 1 - 27760321 HT29 viability after 13 days GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 0.07658805048964745 [255,199] [187,267,374] 0 hSpCas9 negative selection 5269580
182586508 182586530 1 + 27760321 HT29 viability after 13 days GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 0.7262869133112108 [389,304] [984,838,204] 8 hSpCas9 negative selection 5269581
182586602 182586624 1 + 27760321 HT29 viability after 13 days TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 -0.10093308636614684 [224,175] [298,159,192] -1 hSpCas9 negative selection 5269582
182586128 182586150 1 - 27760321 HT29 viability after 10 days GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 -0.062145044880635325 [607,474] [696,629,615] -1 hSpCas9 negative selection 5353041
182586156 182586178 1 + 27760321 HT29 viability after 10 days ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 -0.09720129871501672 [434,339] [623,356,374] -1 hSpCas9 negative selection 5353042
182586203 182586225 1 - 27760321 HT29 viability after 10 days GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 0.13965745491448334 [255,199] [344,242,349] 1 hSpCas9 negative selection 5353043
182586508 182586530 1 + 27760321 HT29 viability after 10 days GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 -0.4379787232206021 [389,304] [433,351,178] -5 hSpCas9 negative selection 5353044
182586602 182586624 1 + 27760321 HT29 viability after 10 days TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 0.019320916802300414 [224,175] [141,379,242] 0 hSpCas9 negative selection 5353045
182586128 182586150 1 - 27760321 MOLM13 viability GCTATTACGCATCTGCTGCTGG RNASEL ENSG00000135828 1.5663892157106838 [617,607] [1161,911] 9 hSpCas9 negative selection 5436504
182586156 182586178 1 + 27760321 MOLM13 viability ATCACTATCGTCAGAGCTCAGG RNASEL ENSG00000135828 0.3331070394272249 [556,434] [213,465] 2 hSpCas9 negative selection 5436505
182586203 182586225 1 - 27760321 MOLM13 viability GTAAACGCCTGTGACAATATGG RNASEL ENSG00000135828 0.5293647031854924 [288,255] [348,112] 3 hSpCas9 negative selection 5436506
182586508 182586530 1 + 27760321 MOLM13 viability GCTGCGAGGATAAAAGGCGTGG RNASEL ENSG00000135828 1.3862941729305753 [510,389] [816,524] 8 hSpCas9 negative selection 5436507
182586602 182586624 1 + 27760321 MOLM13 viability TTTGTACTGCGTTATGCAGAGG RNASEL ENSG00000135828 -0.2135100127989703 [246,224] [211,31] -1 hSpCas9 negative selection 5436508
182588996 182589019 1 + 27661255 K562 viability GAACTCTGGAAGGGCACTGGAGG RNASEL ENSG00000135828 0.1431310072508012 [991,1239] [1054,916] 5 dCas9-KRAB negative selection 5507716
182589231 182589254 1 - 27661255 K562 viability GCAGCAGGAGGAAACTGCTCGGG RNASEL ENSG00000135828 -0.012637579766646145 [339,450] [350,277] 0 dCas9-KRAB negative selection 5507717
182581339 182581362 1 - 27260156 BXPC3 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.030044505084635964 [623] [670,512,462,942] 0 hSpCas9 negative selection 5567530
182581335 182581358 1 + 27260156 BXPC3 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.30314885587934537 [107] [94,73,83,115] -6 hSpCas9 negative selection 5567531
182582116 182582139 1 - 27260156 BXPC3 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.15093734036397222 [1153] [1253,1198,1439,1494] 3 hSpCas9 negative selection 5567532
182582081 182582104 1 - 27260156 BXPC3 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.06120288685588415 [598] [604,549,711,768] 1 hSpCas9 negative selection 5631784
182584125 182584148 1 + 27260156 BXPC3 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.23023879158171856 [802] [706,639,751,771] -5 hSpCas9 negative selection 5631785
182576308 182576331 1 + 27260156 BXPC3 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.014728590149338805 [159] [110,148,237,187] 0 hSpCas9 negative selection 5631786
182581339 182581362 1 - 27260156 A673 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.024457508994783828 [623] [979,672,632,790] 0 hSpCas9 negative selection 5688781
182581335 182581358 1 + 27260156 A673 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.24777782659590541 [107] [132,185,160,130] 6 hSpCas9 negative selection 5688782
182582116 182582139 1 - 27260156 A673 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.28743007772033713 [1153] [1748,1640,1616,1766] 6 hSpCas9 negative selection 5688783
182582081 182582104 1 - 27260156 A673 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.11681090154177065 [598] [879,623,863,763] 3 hSpCas9 negative selection 5753035
182584125 182584148 1 + 27260156 A673 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.08402720531472874 [802] [927,843,813,1063] -2 hSpCas9 negative selection 5753036
182576308 182576331 1 + 27260156 A673 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.4661359091128252 [159] [322,226,264,252] 9 hSpCas9 negative selection 5753037
182581339 182581362 1 - 27260156 A375 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.1551913316668112 [623] [672,798,650,527] -2 hSpCas9 negative selection 5810032
182581335 182581358 1 + 27260156 A375 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.2947385175646402 [107] [64,92,154,96] -4 hSpCas9 negative selection 5810033
182582116 182582139 1 - 27260156 A375 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.555494525771381 [1153] [1687,2426,2703,1245] 7 hSpCas9 negative selection 5810034
182582081 182582104 1 - 27260156 A375 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.1887261286352379 [598] [795,701,1078,617] 2 hSpCas9 negative selection 5874286
182584125 182584148 1 + 27260156 A375 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.40348612074278567 [802] [950,1498,1418,1134] 6 hSpCas9 negative selection 5874287
182576308 182576331 1 + 27260156 A375 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 -0.24385681173337903 [159] [183,167,193,93] -4 hSpCas9 negative selection 5874288
182581339 182581362 1 - 27260156 COLO741 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.016431136944061786 [623] [793,871,703] 0 hSpCas9 negative selection 5931283
182581335 182581358 1 + 27260156 COLO741 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.2843257412688218 [107] [61,181,92] -6 hSpCas9 negative selection 5931284
182582116 182582139 1 - 27260156 COLO741 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.3805327052292613 [1153] [2151,1904,1730] 7 hSpCas9 negative selection 5931285
182582081 182582104 1 - 27260156 COLO741 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.22614973735527183 [598] [1160,876,683] 5 hSpCas9 negative selection 5995537
182584125 182584148 1 + 27260156 COLO741 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.08240406096696185 [802] [1177,970,1112] 1 hSpCas9 negative selection 5995538
182576308 182576331 1 + 27260156 COLO741 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.6451257791984388 [159] [376,152,424] 9 hSpCas9 negative selection 5995539
182581339 182581362 1 - 27260156 CAL120 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.2059375206705562 [623] [541,918,540] -3 hSpCas9 negative selection 6052534
182581335 182581358 1 + 27260156 CAL120 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.396343596970572 [107] [228,28,67] -5 hSpCas9 negative selection 6052535
182582116 182582139 1 - 27260156 CAL120 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.5868508996581487 [1153] [2139,2609,1724] 8 hSpCas9 negative selection 6052536
182582081 182582104 1 - 27260156 CAL120 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.29747761721523475 [598] [613,1093,992] 4 hSpCas9 negative selection 6116788
182584125 182584148 1 + 27260156 CAL120 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.4372745553920051 [802] [1599,1161,1333] 6 hSpCas9 negative selection 6116789
182576308 182576331 1 + 27260156 CAL120 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.08844489114100273 [159] [192,217,220] 1 hSpCas9 negative selection 6116790
182581339 182581362 1 - 27260156 CADOES1 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.20786470894091755 [623] [619,427,394,568] -4 hSpCas9 negative selection 6173785
182581335 182581358 1 + 27260156 CADOES1 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.4146967883010544 [107] [75,116,45,61] -6 hSpCas9 negative selection 6173786
182582116 182582139 1 - 27260156 CADOES1 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.42730794194988997 [1153] [1247,1359,1297,1883] 7 hSpCas9 negative selection 6173787
182582081 182582104 1 - 27260156 CADOES1 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.43852203242686255 [598] [629,738,774,880] 7 hSpCas9 negative selection 6238039
182584125 182584148 1 + 27260156 CADOES1 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.23069076744013517 [802] [859,769,772,1110] 4 hSpCas9 negative selection 6238040
182576308 182576331 1 + 27260156 CADOES1 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 -0.055522015973453964 [159] [140,171,86,173] -1 hSpCas9 negative selection 6238041
182581339 182581362 1 - 27260156 EWS502 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.03849546375482543 [623] [513,689,891,635] 0 hSpCas9 negative selection 6295036
182581335 182581358 1 + 27260156 EWS502 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.2884636861172969 [107] [98,40,101,136] -5 hSpCas9 negative selection 6295037
182582116 182582139 1 - 27260156 EWS502 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.4250715557456324 [1153] [1424,1817,1528,1815] 7 hSpCas9 negative selection 6295038
182582081 182582104 1 - 27260156 EWS502 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.32097146898125367 [598] [840,877,621,815] 5 hSpCas9 negative selection 6359290
182584125 182584148 1 + 27260156 EWS502 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.20027216311654195 [802] [737,800,597,822] -4 hSpCas9 negative selection 6359291
182576308 182576331 1 + 27260156 EWS502 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 -0.12272137376454761 [159] [147,176,202,89] -2 hSpCas9 negative selection 6359292
182581339 182581362 1 - 27260156 EW8 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.09211403489340081 [623] [659,549,504,458] 1 hSpCas9 negative selection 6416287
182581335 182581358 1 + 27260156 EW8 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.1577890649805962 [107] [47,90,43,132] -3 hSpCas9 negative selection 6416288
182582116 182582139 1 - 27260156 EW8 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.3704505427688718 [1153] [1537,1296,946,1131] 6 hSpCas9 negative selection 6416289
182582081 182582104 1 - 27260156 EW8 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.29559455635022897 [598] [685,655,470,599] 5 hSpCas9 negative selection 6480541
182584125 182584148 1 + 27260156 EW8 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.29436560968370207 [802] [813,1092,599,719] 5 hSpCas9 negative selection 6480542
182576308 182576331 1 + 27260156 EW8 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.07244556987144679 [159] [188,138,87,142] 1 hSpCas9 negative selection 6480543
182581339 182581362 1 - 27260156 CORL105 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.14542212419222827 [623] [820,717,685,988] 2 hSpCas9 negative selection 6537538
182581335 182581358 1 + 27260156 CORL105 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.35854951017683145 [107] [139,107,86,58] -6 hSpCas9 negative selection 6537539
182582116 182582139 1 - 27260156 CORL105 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.04003408196666203 [1153] [1477,1099,1661,1366] 0 hSpCas9 negative selection 6537540
182582081 182582104 1 - 27260156 CORL105 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.33449983281019474 [598] [1118,658,939,839] 6 hSpCas9 negative selection 6601792
182584125 182584148 1 + 27260156 CORL105 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.174291420252915 [802] [753,763,988,847] -3 hSpCas9 negative selection 6601793
182576308 182576331 1 + 27260156 CORL105 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.25266785438463435 [159] [127,354,198,200] 5 hSpCas9 negative selection 6601794
182581339 182581362 1 - 27260156 HS294T viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.30130120565612994 [623] [184,169,225,204] -4 hSpCas9 negative selection 6658789
182581335 182581358 1 + 27260156 HS294T viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.1418115394177708 [107] [31,69,34,47] 2 hSpCas9 negative selection 6658790
182582116 182582139 1 - 27260156 HS294T viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.27534638544448087 [1153] [555,521,600,465] 4 hSpCas9 negative selection 6658791
182582081 182582104 1 - 27260156 HS294T viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.5428554027419281 [598] [410,349,221,361] 7 hSpCas9 negative selection 6723043
182584125 182584148 1 + 27260156 HS294T viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.07279825976767018 [802] [208,349,243,549] 1 hSpCas9 negative selection 6723044
182576308 182576331 1 + 27260156 HS294T viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 -0.24707825744981626 [159] [53,21,46,92] -3 hSpCas9 negative selection 6723045
182581339 182581362 1 - 27260156 HCC44 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.10878572719274254 [623] [706,638,959,777] 1 hSpCas9 negative selection 6780040
182581335 182581358 1 + 27260156 HCC44 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.2783742626599657 [107] [149,45,166,63] -4 hSpCas9 negative selection 6780041
182582116 182582139 1 - 27260156 HCC44 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.5555948778285247 [1153] [2324,1633,2504,1389] 8 hSpCas9 negative selection 6780042
182582081 182582104 1 - 27260156 HCC44 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.17012586388900425 [598] [784,629,1059,643] 2 hSpCas9 negative selection 6844294
182584125 182584148 1 + 27260156 HCC44 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.020664908366446633 [802] [1073,730,1246,630] 0 hSpCas9 negative selection 6844295
182576308 182576331 1 + 27260156 HCC44 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.4141421152762004 [159] [440,164,176,198] 6 hSpCas9 negative selection 6844296
182581339 182581362 1 - 27260156 G402 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.3046798707186344 [623] [1200,646,1144,792] 4 hSpCas9 negative selection 6901291
182581335 182581358 1 + 27260156 G402 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.19986492113399024 [107] [303,45,41,90] -3 hSpCas9 negative selection 6901292
182582116 182582139 1 - 27260156 G402 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.5198321212719537 [1153] [3231,1871,1714,1443] 6 hSpCas9 negative selection 6901293
182582081 182582104 1 - 27260156 G402 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.12262893721833434 [598] [745,629,883,897] 1 hSpCas9 negative selection 6965545
182584125 182584148 1 + 27260156 G402 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.3475666820616138 [802] [1334,899,1011,1704] 4 hSpCas9 negative selection 6965546
182576308 182576331 1 + 27260156 G402 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 -0.20101476877503255 [159] [149,187,128,207] -3 hSpCas9 negative selection 6965547
182581339 182581362 1 - 27260156 L33 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.034755638522864674 [623] [610,270,349,606] -1 hSpCas9 negative selection 7022542
182581335 182581358 1 + 27260156 L33 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.0002659453019981939 [107] [116,53,60,85] 0 hSpCas9 negative selection 7022543
182582116 182582139 1 - 27260156 L33 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.17909742254409933 [1153] [1250,561,807,1318] 4 hSpCas9 negative selection 7022544
182582081 182582104 1 - 27260156 L33 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.08376290277321341 [598] [511,251,449,698] 1 hSpCas9 negative selection 7086796
182584125 182584148 1 + 27260156 L33 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.14638887418155333 [802] [650,350,429,711] -3 hSpCas9 negative selection 7086797
182576308 182576331 1 + 27260156 L33 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.14672327104558835 [159] [158,90,88,185] 3 hSpCas9 negative selection 7086798
182581339 182581362 1 - 27260156 K562 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.02441472974273018 [623] [436,643,398,742] 0 hSpCas9 negative selection 7143793
182581335 182581358 1 + 27260156 K562 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.44014105660187086 [107] [124,38,112,225] 5 hSpCas9 negative selection 7143794
182582116 182582139 1 - 27260156 K562 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.26614031107169867 [1153] [920,1115,1474,1361] 3 hSpCas9 negative selection 7143795
182582081 182582104 1 - 27260156 K562 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.2081964524978906 [598] [508,756,707,492] 2 hSpCas9 negative selection 7208047
182584125 182584148 1 + 27260156 K562 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.20504062221482566 [802] [1009,469,495,528] -3 hSpCas9 negative selection 7208048
182576308 182576331 1 + 27260156 K562 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.647006636822774 [159] [124,214,335,205] 8 hSpCas9 negative selection 7208049
182581339 182581362 1 - 27260156 HT29 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.11755003426607313 [623] [712,636,707,725] -2 hSpCas9 negative selection 7265044
182581335 182581358 1 + 27260156 HT29 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.1653027222517347 [107] [162,166,97,160] 3 hSpCas9 negative selection 7265045
182582116 182582139 1 - 27260156 HT29 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.46962079267345636 [1153] [2065,1989,1846,1874] 8 hSpCas9 negative selection 7265046
182582081 182582104 1 - 27260156 HT29 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.3146951957612845 [598] [884,1040,1000,721] 6 hSpCas9 negative selection 7329298
182584125 182584148 1 + 27260156 HT29 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.056194640861244705 [802] [996,1002,1173,623] -1 hSpCas9 negative selection 7329299
182576308 182576331 1 + 27260156 HT29 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.3693105453087413 [159] [200,395,255,168] 7 hSpCas9 negative selection 7329300
182581339 182581362 1 - 27260156 MHHES1 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.3463944697957848 [623] [662,573,413,559] -6 hSpCas9 negative selection 7386295
182581335 182581358 1 + 27260156 MHHES1 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.07509986860139994 [107] [93,207,90,80] -1 hSpCas9 negative selection 7386296
182582116 182582139 1 - 27260156 MHHES1 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.6201636158657886 [1153] [1590,3838,1743,1115] 9 hSpCas9 negative selection 7386297
182582081 182582104 1 - 27260156 MHHES1 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.12712226548941424 [598] [816,923,661,589] 2 hSpCas9 negative selection 7450549
182584125 182584148 1 + 27260156 MHHES1 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.14454176311911815 [802] [1325,860,1143,733] 2 hSpCas9 negative selection 7450550
182576308 182576331 1 + 27260156 MHHES1 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.18774891981633823 [159] [289,339,115,114] 3 hSpCas9 negative selection 7450551
182581339 182581362 1 - 27260156 MEWO viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.09192688611410799 [623] [694,532,652] 2 hSpCas9 negative selection 7507546
182581335 182581358 1 + 27260156 MEWO viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.2957414944583965 [107] [87,86,72] -6 hSpCas9 negative selection 7507547
182582116 182582139 1 - 27260156 MEWO viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.4133412666728713 [1153] [1445,1589,1277] 8 hSpCas9 negative selection 7507548
182582081 182582104 1 - 27260156 MEWO viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.1854898736838379 [598] [739,560,630] 4 hSpCas9 negative selection 7571800
182584125 182584148 1 + 27260156 MEWO viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.18193206068760726 [802] [869,630,525] -4 hSpCas9 negative selection 7571801
182576308 182576331 1 + 27260156 MEWO viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.1548334618025271 [159] [187,175,139] 3 hSpCas9 negative selection 7571802
182581339 182581362 1 - 27260156 LNCAPCLONEFGC viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.09017723836246033 [623] [542,695,686,487] 1 hSpCas9 negative selection 7628797
182581335 182581358 1 + 27260156 LNCAPCLONEFGC viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.4832317638883201 [107] [84,38,105,56] -6 hSpCas9 negative selection 7628798
182582116 182582139 1 - 27260156 LNCAPCLONEFGC viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.4253777321199528 [1153] [1246,1189,1682,1552] 6 hSpCas9 negative selection 7628799
182582081 182582104 1 - 27260156 LNCAPCLONEFGC viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.33904998004479986 [598] [892,402,856,631] 5 hSpCas9 negative selection 7693051
182584125 182584148 1 + 27260156 LNCAPCLONEFGC viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.09173383365269339 [802] [751,423,1052,935] 1 hSpCas9 negative selection 7693052
182576308 182576331 1 + 27260156 LNCAPCLONEFGC viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.23096746268031554 [159] [161,180,144,187] 3 hSpCas9 negative selection 7693053
182581339 182581362 1 - 27260156 PANC0327 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.05149347531227749 [623] [614,435,694,412] 0 hSpCas9 negative selection 7750048
182581335 182581358 1 + 27260156 PANC0327 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.675126300736975 [107] [158,8,41,44] -7 hSpCas9 negative selection 7750049
182582116 182582139 1 - 27260156 PANC0327 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.3267018871573193 [1153] [1295,1208,1357,1289] 5 hSpCas9 negative selection 7750050
182582081 182582104 1 - 27260156 PANC0327 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.5949387621571527 [598] [871,860,897,581] 8 hSpCas9 negative selection 7814302
182584125 182584148 1 + 27260156 PANC0327 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.20335236578051785 [802] [1088,819,746,650] 3 hSpCas9 negative selection 7814303
182576308 182576331 1 + 27260156 PANC0327 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.9796409448727563 [159] [178,223,333,382] 9 hSpCas9 negative selection 7814304
182581339 182581362 1 - 27260156 NCIH2009 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.3128325813835855 [623] [859,573,703] -4 hSpCas9 negative selection 7871299
182581335 182581358 1 + 27260156 NCIH2009 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.2746814735263774 [107] [217,199,135] 4 hSpCas9 negative selection 7871300
182582116 182582139 1 - 27260156 NCIH2009 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.2788588737338362 [1153] [1886,1921,2042] 4 hSpCas9 negative selection 7871301
182582081 182582104 1 - 27260156 NCIH2009 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.10496534846583905 [598] [959,926,822] 1 hSpCas9 negative selection 7935553
182584125 182584148 1 + 27260156 NCIH2009 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.0924727293042199 [802] [1646,789,1245] 1 hSpCas9 negative selection 7935554
182576308 182576331 1 + 27260156 NCIH2009 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 -0.1722699887049397 [159] [221,224,151] -2 hSpCas9 negative selection 7935555
182581339 182581362 1 - 27260156 NCIH1373 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.569118735531277 [623] [424,584,456,102] -5 hSpCas9 negative selection 7992550
182581335 182581358 1 + 27260156 NCIH1373 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.12932723858567852 [107] [83,159,84,50] 1 hSpCas9 negative selection 7992551
182582116 182582139 1 - 27260156 NCIH1373 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.3111188756558565 [1153] [2125,1155,1014,603] 3 hSpCas9 negative selection 7992552
182582081 182582104 1 - 27260156 NCIH1373 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.5644781695423355 [598] [1650,916,938,142] 5 hSpCas9 negative selection 8056804
182584125 182584148 1 + 27260156 NCIH1373 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.19699593755564782 [802] [1457,575,1088,293] 2 hSpCas9 negative selection 8056805
182576308 182576331 1 + 27260156 NCIH1373 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 -0.8780493985918942 [159] [86,69,60,46] -7 hSpCas9 negative selection 8056806
182581339 182581362 1 - 27260156 PATU8902 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.011429637918624502 [623] [908,951,719,966] 0 hSpCas9 negative selection 8113801
182581335 182581358 1 + 27260156 PATU8902 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.5629251076465343 [107] [109,68,132,83] -5 hSpCas9 negative selection 8113802
182582116 182582139 1 - 27260156 PATU8902 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.17768117247787774 [1153] [1611,1524,2117,1939] 1 hSpCas9 negative selection 8113803
182582081 182582104 1 - 27260156 PATU8902 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.5102779182881585 [598] [1060,950,1214,1553] 5 hSpCas9 negative selection 8178055
182584125 182584148 1 + 27260156 PATU8902 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.24871819294487285 [802] [1128,449,931,1285] -3 hSpCas9 negative selection 8178056
182576308 182576331 1 + 27260156 PATU8902 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 -0.12346480117508318 [159] [161,181,363,48] -1 hSpCas9 negative selection 8178057
182581339 182581362 1 - 27260156 PANC1 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.1338344509258072 [623] [556,633,643,527] 2 hSpCas9 negative selection 8235052
182581335 182581358 1 + 27260156 PANC1 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.8562426477825815 [107] [158,233,112,174] 9 hSpCas9 negative selection 8235053
182582116 182582139 1 - 27260156 PANC1 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.5442701453443146 [1153] [1547,1355,1418,1417] 8 hSpCas9 negative selection 8235054
182582081 182582104 1 - 27260156 PANC1 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.23510023778793881 [598] [374,734,988,384] 4 hSpCas9 negative selection 8299306
182584125 182584148 1 + 27260156 PANC1 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.34814753249058683 [802] [776,976,896,869] 5 hSpCas9 negative selection 8299307
182576308 182576331 1 + 27260156 PANC1 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.7349896130494704 [159] [193,403,232,132] 9 hSpCas9 negative selection 8299308
182581339 182581362 1 - 27260156 PANC0813 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.2092050331086695 [623] [1134,879,753,655] 3 hSpCas9 negative selection 8356303
182581335 182581358 1 + 27260156 PANC0813 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.026262873954977728 [107] [156,52,275,38] 0 hSpCas9 negative selection 8356304
182582116 182582139 1 - 27260156 PANC0813 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.36516001142104604 [1153] [1930,1733,1752,1588] 6 hSpCas9 negative selection 8356305
182582081 182582104 1 - 27260156 PANC0813 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.3036047314774422 [598] [835,884,926,823] 5 hSpCas9 negative selection 8420557
182584125 182584148 1 + 27260156 PANC0813 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.28050718812991327 [802] [1048,677,685,719] -4 hSpCas9 negative selection 8420558
182576308 182576331 1 + 27260156 PANC0813 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.08243502390079027 [159] [180,163,142,299] 1 hSpCas9 negative selection 8420559
182581339 182581362 1 - 27260156 RDES viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.30633240970591924 [623] [519,471,507,867] -5 hSpCas9 negative selection 8477554
182581335 182581358 1 + 27260156 RDES viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.18704199893251117 [107] [148,68,83,126] -3 hSpCas9 negative selection 8477555
182582116 182582139 1 - 27260156 RDES viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.3317991551265216 [1153] [1266,1636,1976,1885] 5 hSpCas9 negative selection 8477556
182582081 182582104 1 - 27260156 RDES viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.2484588782114961 [598] [724,657,922,1010] 4 hSpCas9 negative selection 8541808
182584125 182584148 1 + 27260156 RDES viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.15765185519291558 [802] [923,989,1088,1127] 2 hSpCas9 negative selection 8541809
182576308 182576331 1 + 27260156 RDES viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.026879485009088322 [159] [151,163,257,181] 0 hSpCas9 negative selection 8541810
182581339 182581362 1 - 27260156 PC3 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.15706874871558135 [623] [436,637,1205,742] 3 hSpCas9 negative selection 8598805
182581335 182581358 1 + 27260156 PC3 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.6646727954418135 [107] [99,206,185,209] 9 hSpCas9 negative selection 8598806
182582116 182582139 1 - 27260156 PC3 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.289027474090537 [1153] [867,1316,2713,1335] 6 hSpCas9 negative selection 8598807
182582081 182582104 1 - 27260156 PC3 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 -0.16754999709698656 [598] [364,514,958,468] -4 hSpCas9 negative selection 8663059
182584125 182584148 1 + 27260156 PC3 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.007252189789917929 [802] [645,774,1076,797] 0 hSpCas9 negative selection 8663060
182576308 182576331 1 + 27260156 PC3 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.24910097473171078 [159] [158,71,388,213] 5 hSpCas9 negative selection 8663061
182581339 182581362 1 - 27260156 PATU8988T viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.3007511720770802 [623] [730,850,677,719] 5 hSpCas9 negative selection 8720056
182581335 182581358 1 + 27260156 PATU8988T viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.6219293853456718 [107] [189,153,196,94] 8 hSpCas9 negative selection 8720057
182582116 182582139 1 - 27260156 PATU8988T viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.5054831322721285 [1153] [1856,1594,1074,1832] 8 hSpCas9 negative selection 8720058
182582081 182582104 1 - 27260156 PATU8988T viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.2919486873045673 [598] [721,639,583,898] 5 hSpCas9 negative selection 8784310
182584125 182584148 1 + 27260156 PATU8988T viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.12884694474190106 [802] [828,719,730,545] -2 hSpCas9 negative selection 8784311
182576308 182576331 1 + 27260156 PATU8988T viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.43598640843270675 [159] [135,325,117,273] 7 hSpCas9 negative selection 8784312
182581339 182581362 1 - 27260156 T47D viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.11421200860635222 [623] [817,558,547,776] -3 hSpCas9 negative selection 8841307
182581335 182581358 1 + 27260156 T47D viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.2348258973806474 [107] [87,128,95,112] -5 hSpCas9 negative selection 8841308
182582116 182582139 1 - 27260156 T47D viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.37099889911764405 [1153] [1713,1653,1718,1878] 7 hSpCas9 negative selection 8841309
182582081 182582104 1 - 27260156 T47D viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.1606645946475907 [598] [825,638,797,871] 3 hSpCas9 negative selection 8905561
182584125 182584148 1 + 27260156 T47D viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.012652885401613356 [802] [952,995,879,941] 0 hSpCas9 negative selection 8905562
182576308 182576331 1 + 27260156 T47D viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.41210119259082 [159] [280,266,201,240] 8 hSpCas9 negative selection 8905563
182581339 182581362 1 - 27260156 SU8686 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.013088678900915196 [623] [485,644,605,795] 0 hSpCas9 negative selection 8962558
182581335 182581358 1 + 27260156 SU8686 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.35834165031370513 [107] [108,97,142,219] 6 hSpCas9 negative selection 8962559
182582116 182582139 1 - 27260156 SU8686 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.3037232906141252 [1153] [1159,1248,1540,1805] 5 hSpCas9 negative selection 8962560
182582081 182582104 1 - 27260156 SU8686 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.3440408669665755 [598] [701,664,763,923] 6 hSpCas9 negative selection 9026812
182584125 182584148 1 + 27260156 SU8686 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.1317703822560763 [802] [848,724,905,1054] 2 hSpCas9 negative selection 9026813
182576308 182576331 1 + 27260156 SU8686 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 -0.05354773382058986 [159] [81,180,137,224] -1 hSpCas9 negative selection 9026814
182581339 182581362 1 - 27260156 SKES1 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.05421218598403549 [623] [822,661,457,500] -1 hSpCas9 negative selection 9083809
182581335 182581358 1 + 27260156 SKES1 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.08414480056411877 [107] [143,84,172,59] 1 hSpCas9 negative selection 9083810
182582116 182582139 1 - 27260156 SKES1 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.3448215057644881 [1153] [1582,1502,1546,1245] 7 hSpCas9 negative selection 9083811
182582081 182582104 1 - 27260156 SKES1 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.05917389233642567 [598] [606,681,565,632] 1 hSpCas9 negative selection 9148063
182584125 182584148 1 + 27260156 SKES1 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.20028287722134652 [802] [774,664,725,629] -4 hSpCas9 negative selection 9148064
182576308 182576331 1 + 27260156 SKES1 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.6028972602837439 [159] [330,253,165,231] 9 hSpCas9 negative selection 9148065
182581339 182581362 1 - 27260156 TOV112D viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 0.025943740032199458 [623] [603,1147,518,402] 0 hSpCas9 negative selection 9205060
182581335 182581358 1 + 27260156 TOV112D viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.21197242116880544 [107] [112,70,108,76] -4 hSpCas9 negative selection 9205061
182582116 182582139 1 - 27260156 TOV112D viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.3680117804860872 [1153] [1440,1819,1483,1300] 7 hSpCas9 negative selection 9205062
182582081 182582104 1 - 27260156 TOV112D viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.33973370488067084 [598] [706,1216,536,684] 6 hSpCas9 negative selection 9269314
182584125 182584148 1 + 27260156 TOV112D viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.08575101086884829 [802] [770,750,984,528] -2 hSpCas9 negative selection 9269315
182576308 182576331 1 + 27260156 TOV112D viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 -0.5733015860178698 [159] [128,141,139,31] -8 hSpCas9 negative selection 9269316
182581339 182581362 1 - 27260156 TC71 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.04084866030720352 [623] [680,640,616,662] -1 hSpCas9 negative selection 9326311
182581335 182581358 1 + 27260156 TC71 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 0.4603456994090027 [107] [270,114,99,149] 9 hSpCas9 negative selection 9326312
182582116 182582139 1 - 27260156 TC71 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.27110468369389484 [1153] [1503,1372,1459,1643] 6 hSpCas9 negative selection 9326313
182582081 182582104 1 - 27260156 TC71 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.1521628454564013 [598] [781,650,742,672] 4 hSpCas9 negative selection 9390565
182584125 182584148 1 + 27260156 TC71 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 -0.0888524475051804 [802] [744,844,796,854] -2 hSpCas9 negative selection 9390566
182576308 182576331 1 + 27260156 TC71 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 0.27018431468279136 [159] [203,185,245,188] 6 hSpCas9 negative selection 9390567
182581339 182581362 1 - 27260156 TC32 viability TCAGCCGCTATAGGACGCTTCGG RNASEL ENSG00000135828 -0.36232115001514453 [623] [417,469,588,332] -6 hSpCas9 negative selection 9447562
182581335 182581358 1 + 27260156 TC32 viability CATTCCGAAGCGTCCTATAGCGG RNASEL ENSG00000135828 -0.15619253359128926 [107] [153,12,124,94] -3 hSpCas9 negative selection 9447563
182582116 182582139 1 - 27260156 TC32 viability ATTCATCGTCTCTTCCATCCTGG RNASEL ENSG00000135828 0.2781395788880867 [1153] [1321,975,1486,1566] 5 hSpCas9 negative selection 9447564
182582081 182582104 1 - 27260156 TC32 viability GGACTGTCTGAGTGACCTGCTGG RNASEL ENSG00000135828 0.34905110161992076 [598] [654,575,943,751] 6 hSpCas9 negative selection 9511816
182584125 182584148 1 + 27260156 TC32 viability TGCTCTTATCAAAATCTGCCAGG RNASEL ENSG00000135828 0.04743465976326977 [802] [611,699,1116,750] 0 hSpCas9 negative selection 9511817
182576308 182576331 1 + 27260156 TC32 viability GCAGATCACCCACAGTGTTCTGG RNASEL ENSG00000135828 -0.18123153074864828 [159] [126,141,127,119] -3 hSpCas9 negative selection 9511818
182575382 182575405 1 + 27869803 HPAFII viability after 27 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -0.8158891740064493 [255] [28,115,NaN] -5 hSpCas9 negative selection 9530890
182582222 182582245 1 - 27869803 HPAFII viability after 27 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 1.106022867498005 [115] [85,168,NaN] 8 hSpCas9 negative selection 9530891
182582243 182582266 1 - 27869803 HPAFII viability after 27 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 1.3862231698396004 [256] [482,244,NaN] 9 hSpCas9 negative selection 9530892
182584143 182584166 1 - 27869803 HPAFII viability after 27 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 -1.0155303291455682 [164] [67,21,NaN] -6 hSpCas9 negative selection 9530893
182585525 182585548 1 - 27869803 HPAFII viability after 27 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.5116504743749926 [440] [437,240,NaN] 4 hSpCas9 negative selection 9530894
182585526 182585549 1 - 27869803 HPAFII viability after 27 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -2.518045364736563 [103] [14,4,NaN] -8 hSpCas9 negative selection 9530895
182575382 182575405 1 + 27869803 HPAFII viability after 15 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -0.4406864984242602 [255] [153,232,NaN] -5 hSpCas9 negative selection 9613339
182582222 182582245 1 - 27869803 HPAFII viability after 15 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 0.6674270877476005 [115] [234,174,NaN] 7 hSpCas9 negative selection 9613340
182582243 182582266 1 - 27869803 HPAFII viability after 15 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 1.0849405194851192 [256] [707,509,NaN] 9 hSpCas9 negative selection 9613341
182584143 182584166 1 - 27869803 HPAFII viability after 15 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 -0.06456867430058078 [164] [192,154,NaN] 0 hSpCas9 negative selection 9613342
182585525 182585548 1 - 27869803 HPAFII viability after 15 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.43368532790950653 [440] [596,666,NaN] 5 hSpCas9 negative selection 9613343
182585526 182585549 1 - 27869803 HPAFII viability after 15 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -0.1456978685713377 [103] [121,87,NaN] -2 hSpCas9 negative selection 9613344
182575382 182575405 1 + 27869803 ASPC1 viability after 36 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -0.22795756093248348 [754] [393,102,200] -2 hSpCas9 negative selection 9695788
182582222 182582245 1 - 27869803 ASPC1 viability after 36 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 -0.2211897762803836 [288] [143,125,13] -2 hSpCas9 negative selection 9695789
182582243 182582266 1 - 27869803 ASPC1 viability after 36 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 -0.2849511619536218 [852] [279,446,55] -3 hSpCas9 negative selection 9695790
182584143 182584166 1 - 27869803 ASPC1 viability after 36 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 0.19370404250896966 [347] [70,60,246] 2 hSpCas9 negative selection 9695791
182585525 182585548 1 - 27869803 ASPC1 viability after 36 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.09732234492796787 [959] [328,159,532] 0 hSpCas9 negative selection 9695792
182585526 182585549 1 - 27869803 ASPC1 viability after 36 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 0.24851735337982728 [260] [12,189,108] 2 hSpCas9 negative selection 9695793
182575382 182575405 1 + 27869803 PATU8988S viability after 35 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -0.15787005576342178 [546] [183,210,NaN] -2 hSpCas9 negative selection 9778237
182582222 182582245 1 - 27869803 PATU8988S viability after 35 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 0.38191178168199147 [221] [119,112,NaN] 4 hSpCas9 negative selection 9778238
182582243 182582266 1 - 27869803 PATU8988S viability after 35 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 -0.08595360320168169 [591] [284,163,NaN] -1 hSpCas9 negative selection 9778239
182584143 182584166 1 - 27869803 PATU8988S viability after 35 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 0.03072804160339926 [294] [63,178,NaN] 0 hSpCas9 negative selection 9778240
182585525 182585548 1 - 27869803 PATU8988S viability after 35 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 -0.3561931336207418 [864] [342,200,NaN] -4 hSpCas9 negative selection 9778241
182585526 182585549 1 - 27869803 PATU8988S viability after 35 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 0.015506368431992934 [194] [28,129,NaN] 0 hSpCas9 negative selection 9778242
182575382 182575405 1 + 27869803 PATU8988S viability after 31 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 0.4806002166693722 [546] [196,440,NaN] 6 hSpCas9 negative selection 9860686
182582222 182582245 1 - 27869803 PATU8988S viability after 31 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 0.29602769869211754 [221] [120,92,NaN] 3 hSpCas9 negative selection 9860687
182582243 182582266 1 - 27869803 PATU8988S viability after 31 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 0.09730239101151478 [591] [281,214,NaN] 1 hSpCas9 negative selection 9860688
182584143 182584166 1 - 27869803 PATU8988S viability after 31 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 -0.03167545260676241 [294] [89,146,NaN] 0 hSpCas9 negative selection 9860689
182585525 182585548 1 - 27869803 PATU8988S viability after 31 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 -0.2806876252166683 [864] [341,209,NaN] -3 hSpCas9 negative selection 9860690
182585526 182585549 1 - 27869803 PATU8988S viability after 31 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -0.5906512968331425 [194] [15,96,NaN] -6 hSpCas9 negative selection 9860691
182575382 182575405 1 + 27869803 HPAFII viability after 35 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -0.5350835660538604 [255] [24,161,NaN] -3 hSpCas9 negative selection 9943135
182582222 182582245 1 - 27869803 HPAFII viability after 35 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 0.1785751415887381 [115] [49,84,NaN] 1 hSpCas9 negative selection 9943136
182582243 182582266 1 - 27869803 HPAFII viability after 35 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 1.5613225516549887 [256] [446,312,NaN] 9 hSpCas9 negative selection 9943137
182584143 182584166 1 - 27869803 HPAFII viability after 35 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 -1.0988314423868921 [164] [38,38,NaN] -6 hSpCas9 negative selection 9943138
182585525 182585548 1 - 27869803 HPAFII viability after 35 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.8017981647911996 [440] [423,349,NaN] 5 hSpCas9 negative selection 9943139
182585526 182585549 1 - 27869803 HPAFII viability after 35 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -1.4836899064747051 [103] [23,12,NaN] -7 hSpCas9 negative selection 9943140
182575382 182575405 1 + 27869803 HPAFII viability after 31 days AATCAGTCCATCAGCACCCAGGG RNASEL ENSG00000135828 -1.1867341139144338 [255] [20,108,NaN] -6 hSpCas9 negative selection 10025584
182582222 182582245 1 - 27869803 HPAFII viability after 31 days GGTCCTCTATGTGGTAAAGAAGG RNASEL ENSG00000135828 0.6989292636840029 [115] [64,149,NaN] 5 hSpCas9 negative selection 10025585
182582243 182582266 1 - 27869803 HPAFII viability after 31 days TGTGCAGGACCTTGGACGGCTGG RNASEL ENSG00000135828 1.5458391285087176 [256] [501,332,NaN] 9 hSpCas9 negative selection 10025586
182584143 182584166 1 - 27869803 HPAFII viability after 31 days TTCTAAGAAAGCTGCTCACCTGG RNASEL ENSG00000135828 -0.489806522870042 [164] [86,42,NaN] -3 hSpCas9 negative selection 10025587
182585525 182585548 1 - 27869803 HPAFII viability after 31 days CTATGGGAGTGAGAGCCACAGGG RNASEL ENSG00000135828 0.637263614540196 [440] [394,373,NaN] 4 hSpCas9 negative selection 10025588
182585526 182585549 1 - 27869803 HPAFII viability after 31 days TCTATGGGAGTGAGAGCCACAGG RNASEL ENSG00000135828 -2.3798026916318116 [103] [15,5,NaN] -8 hSpCas9 negative selection 10025589
182586302 182586325 1 - 28162770 P31FUJ viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 -0.8268098447385417 [79] [52] -6 hSpCas9 negative selection 10225888
182585617 182585640 1 - 28162770 P31FUJ viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 0.33614007571630533 [814] [1208] 3 hSpCas9 negative selection 10225889
182585846 182585869 1 + 28162770 P31FUJ viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 0.09734639727795213 [384] [483] 1 hSpCas9 negative selection 10225890
182585723 182585746 1 + 28162770 P31FUJ viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 -0.07660609772664828 [480] [535] 0 hSpCas9 negative selection 10225891
182585598 182585621 1 - 28162770 P31FUJ viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 0.5312686199144254 [115] [196] 6 hSpCas9 negative selection 10225892
182586754 182586777 1 - 28162770 P31FUJ viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 0.24232574470079457 [240] [334] 2 hSpCas9 negative selection 10225893
182586329 182586352 1 - 28162770 P31FUJ viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 1.0947724536141257 [101] [255] 9 hSpCas9 negative selection 10225894
182586233 182586256 1 - 28162770 P31FUJ viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 0.3081356724147794 [243] [354] 3 hSpCas9 negative selection 10225895
182585776 182585799 1 - 28162770 P31FUJ viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 0.15532742140094813 [229] [300] 1 hSpCas9 negative selection 10225896
182585661 182585684 1 - 28162770 P31FUJ viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 -0.1638244624957952 [632] [663] -1 hSpCas9 negative selection 10225897
182586302 182586325 1 - 28162770 TF1 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 NaN [NaN] [67] 1 hSpCas9 negative selection 10395254
182585617 182585640 1 - 28162770 TF1 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 NaN [NaN] [581] 1 hSpCas9 negative selection 10395255
182585846 182585869 1 + 28162770 TF1 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 NaN [NaN] [374] 1 hSpCas9 negative selection 10395256
182585723 182585746 1 + 28162770 TF1 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 NaN [NaN] [333] 1 hSpCas9 negative selection 10395257
182585598 182585621 1 - 28162770 TF1 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 NaN [NaN] [133] 1 hSpCas9 negative selection 10395258
182586754 182586777 1 - 28162770 TF1 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 NaN [NaN] [204] 1 hSpCas9 negative selection 10395259
182586329 182586352 1 - 28162770 TF1 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 NaN [NaN] [120] 1 hSpCas9 negative selection 10395260
182586233 182586256 1 - 28162770 TF1 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 NaN [NaN] [201] 1 hSpCas9 negative selection 10395261
182585776 182585799 1 - 28162770 TF1 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 NaN [NaN] [283] 1 hSpCas9 negative selection 10395262
182585661 182585684 1 - 28162770 TF1 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 NaN [NaN] [419] 1 hSpCas9 negative selection 10395263
182586302 182586325 1 - 28162770 SKM1 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 0.1779983019779945 [21] [43] 1 hSpCas9 negative selection 10564620
182585617 182585640 1 - 28162770 SKM1 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 0.6758622323864585 [164] [465] 6 hSpCas9 negative selection 10564621
182585846 182585869 1 + 28162770 SKM1 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 -0.4395320611995924 [111] [145] -4 hSpCas9 negative selection 10564622
182585723 182585746 1 + 28162770 SKM1 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 -0.0747677684019723 [139] [234] 0 hSpCas9 negative selection 10564623
182585598 182585621 1 - 28162770 SKM1 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 0.008073300535682226 [35] [63] 0 hSpCas9 negative selection 10564624
182586754 182586777 1 - 28162770 SKM1 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.7863777882912841 [79] [81] -5 hSpCas9 negative selection 10564625
182586329 182586352 1 - 28162770 SKM1 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 -0.17563865263670597 [22] [35] -1 hSpCas9 negative selection 10564626
182586233 182586256 1 - 28162770 SKM1 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 0.48056107199842585 [59] [147] 4 hSpCas9 negative selection 10564627
182585776 182585799 1 - 28162770 SKM1 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 -0.7789329761301196 [65] [67] -5 hSpCas9 negative selection 10564628
182585661 182585684 1 - 28162770 SKM1 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 0.25756555929631264 [96] [204] 2 hSpCas9 negative selection 10564629
182586302 182586325 1 - 28162770 SKM1 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 0.1779983019779945 [21] [43] 1 hSpCas9 negative selection 10733986
182585617 182585640 1 - 28162770 SKM1 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 0.6758622323864585 [164] [465] 6 hSpCas9 negative selection 10733987
182585846 182585869 1 + 28162770 SKM1 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 -0.4395320611995924 [111] [145] -4 hSpCas9 negative selection 10733988
182585723 182585746 1 + 28162770 SKM1 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 -0.0747677684019723 [139] [234] 0 hSpCas9 negative selection 10733989
182585598 182585621 1 - 28162770 SKM1 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 0.008073300535682226 [35] [63] 0 hSpCas9 negative selection 10733990
182586754 182586777 1 - 28162770 SKM1 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.7863777882912841 [79] [81] -5 hSpCas9 negative selection 10733991
182586329 182586352 1 - 28162770 SKM1 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 -0.17563865263670597 [22] [35] -1 hSpCas9 negative selection 10733992
182586233 182586256 1 - 28162770 SKM1 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 0.48056107199842585 [59] [147] 4 hSpCas9 negative selection 10733993
182585776 182585799 1 - 28162770 SKM1 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 -0.7789329761301196 [65] [67] -5 hSpCas9 negative selection 10733994
182585661 182585684 1 - 28162770 SKM1 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 0.25756555929631264 [96] [204] 2 hSpCas9 negative selection 10733995
182586302 182586325 1 - 28162770 PL21 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 -0.9345099122054614 [100] [22] -6 hSpCas9 negative selection 10903352
182585617 182585640 1 - 28162770 PL21 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 -0.40535981723453074 [565] [185] -3 hSpCas9 negative selection 10903353
182585846 182585869 1 + 28162770 PL21 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 -0.2674097219506655 [400] [144] -2 hSpCas9 negative selection 10903354
182585723 182585746 1 + 28162770 PL21 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.12762711470495214 [407] [193] 1 hSpCas9 negative selection 10903355
182585598 182585621 1 - 28162770 PL21 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 0.22438716073599757 [117] [59] 2 hSpCas9 negative selection 10903356
182586754 182586777 1 - 28162770 PL21 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.654767237048303 [292] [80] -4 hSpCas9 negative selection 10903357
182586329 182586352 1 - 28162770 PL21 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 -2.865949575968453 [66] [3] -9 hSpCas9 negative selection 10903358
182586233 182586256 1 - 28162770 PL21 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 -0.8689020299403313 [213] [50] -5 hSpCas9 negative selection 10903359
182585776 182585799 1 - 28162770 PL21 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 -0.71287708391604 [176] [46] -5 hSpCas9 negative selection 10903360
182585661 182585684 1 - 28162770 PL21 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 0.4175771538830034 [374] [217] 3 hSpCas9 negative selection 10903361
182586302 182586325 1 - 28162770 P31FUJ viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 -0.8268098447385417 [79] [52] -6 hSpCas9 negative selection 11072718
182585617 182585640 1 - 28162770 P31FUJ viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 0.33614007571630533 [814] [1208] 3 hSpCas9 negative selection 11072719
182585846 182585869 1 + 28162770 P31FUJ viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 0.09734639727795213 [384] [483] 1 hSpCas9 negative selection 11072720
182585723 182585746 1 + 28162770 P31FUJ viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 -0.07660609772664828 [480] [535] 0 hSpCas9 negative selection 11072721
182585598 182585621 1 - 28162770 P31FUJ viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 0.5312686199144254 [115] [196] 6 hSpCas9 negative selection 11072722
182586754 182586777 1 - 28162770 P31FUJ viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 0.24232574470079457 [240] [334] 2 hSpCas9 negative selection 11072723
182586329 182586352 1 - 28162770 P31FUJ viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 1.0947724536141257 [101] [255] 9 hSpCas9 negative selection 11072724
182586233 182586256 1 - 28162770 P31FUJ viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 0.3081356724147794 [243] [354] 3 hSpCas9 negative selection 11072725
182585776 182585799 1 - 28162770 P31FUJ viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 0.15532742140094813 [229] [300] 1 hSpCas9 negative selection 11072726
182585661 182585684 1 - 28162770 P31FUJ viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 -0.1638244624957952 [632] [663] -1 hSpCas9 negative selection 11072727
182586302 182586325 1 - 28162770 OCIAML5 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 0.45171417731310615 [31] [78] 4 hSpCas9 negative selection 11242084
182585617 182585640 1 - 28162770 OCIAML5 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 -0.22351480159515802 [488] [755] -2 hSpCas9 negative selection 11242085
182585846 182585869 1 + 28162770 OCIAML5 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 1.1010123817485105 [124] [483] 8 hSpCas9 negative selection 11242086
182585723 182585746 1 + 28162770 OCIAML5 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 -0.049041902305126284 [285] [498] 0 hSpCas9 negative selection 11242087
182585598 182585621 1 - 28162770 OCIAML5 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 0.46986152402336545 [47] [119] 4 hSpCas9 negative selection 11242088
182586754 182586777 1 - 28162770 OCIAML5 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.21374084454411568 [114] [178] -1 hSpCas9 negative selection 11242089
182586329 182586352 1 - 28162770 OCIAML5 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 1.0460538151167897 [32] [122] 8 hSpCas9 negative selection 11242090
182586233 182586256 1 - 28162770 OCIAML5 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 1.0315047541593967 [157] [582] 8 hSpCas9 negative selection 11242091
182585776 182585799 1 - 28162770 OCIAML5 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 -0.9600492517370087 [207] [192] -6 hSpCas9 negative selection 11242092
182585661 182585684 1 - 28162770 OCIAML5 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 0.24226081168415625 [258] [552] 2 hSpCas9 negative selection 11242093
182586302 182586325 1 - 28162770 EOL1 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 -1.10144743696241 [223] [54] -6 hSpCas9 negative selection 11411450
182585617 182585640 1 - 28162770 EOL1 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 0.11555806742198516 [882] [503] 1 hSpCas9 negative selection 11411451
182585846 182585869 1 + 28162770 EOL1 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 0.7529824117469666 [659] [585] 6 hSpCas9 negative selection 11411452
182585723 182585746 1 + 28162770 EOL1 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.8895480621900747 [750] [732] 7 hSpCas9 negative selection 11411453
182585598 182585621 1 - 28162770 EOL1 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 -0.17060946146980577 [234] [109] -1 hSpCas9 negative selection 11411454
182586754 182586777 1 - 28162770 EOL1 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.1846156719171992 [493] [228] -1 hSpCas9 negative selection 11411455
182586329 182586352 1 - 28162770 EOL1 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 -2.308112985219741 [93] [9] -8 hSpCas9 negative selection 11411456
182586233 182586256 1 - 28162770 EOL1 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 0.11240778694755359 [301] [171] 1 hSpCas9 negative selection 11411457
182585776 182585799 1 - 28162770 EOL1 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 -0.3264138019626842 [237] [99] -2 hSpCas9 negative selection 11411458
182585661 182585684 1 - 28162770 EOL1 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 -0.32685863201042004 [518] [217] -2 hSpCas9 negative selection 11411459
182586302 182586325 1 - 28162770 MOLM13 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 0.26065676737913657 [141] [122] 1 hSpCas9 negative selection 11580816
182585617 182585640 1 - 28162770 MOLM13 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 0.27691505658669646 [862] [755] 2 hSpCas9 negative selection 11580817
182585846 182585869 1 + 28162770 MOLM13 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 0.5446151721874073 [475] [501] 4 hSpCas9 negative selection 11580818
182585723 182585746 1 + 28162770 MOLM13 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.6811707521812729 [589] [683] 5 hSpCas9 negative selection 11580819
182585598 182585621 1 - 28162770 MOLM13 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 1.2199618681009934 [189] [319] 8 hSpCas9 negative selection 11580820
182586754 182586777 1 - 28162770 MOLM13 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.08258474279128658 [371] [253] 0 hSpCas9 negative selection 11580821
182586329 182586352 1 - 28162770 MOLM13 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 -1.1668261543736769 [117] [37] -6 hSpCas9 negative selection 11580822
182586233 182586256 1 - 28162770 MOLM13 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 1.1572626043018421 [301] [486] 8 hSpCas9 negative selection 11580823
182585776 182585799 1 - 28162770 MOLM13 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 -0.562916665236596 [283] [138] -3 hSpCas9 negative selection 11580824
182585661 182585684 1 - 28162770 MOLM13 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 1.3568580691558347 [458] [849] 9 hSpCas9 negative selection 11580825
182586302 182586325 1 - 28162770 HEL viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 0.47648948870144303 [146] [130] 4 hSpCas9 negative selection 11750182
182585617 182585640 1 - 28162770 HEL viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 -0.3041273454695703 [772] [400] -2 hSpCas9 negative selection 11750183
182585846 182585869 1 + 28162770 HEL viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 0.5574915453818459 [487] [459] 5 hSpCas9 negative selection 11750184
182585723 182585746 1 + 28162770 HEL viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.30570384472278644 [527] [417] 2 hSpCas9 negative selection 11750185
182585598 182585621 1 - 28162770 HEL viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 0.6502725046857645 [190] [191] 5 hSpCas9 negative selection 11750186
182586754 182586777 1 - 28162770 HEL viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.503809831352585 [351] [158] -3 hSpCas9 negative selection 11750187
182586329 182586352 1 - 28162770 HEL viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 0.9771578710709161 [45] [57] 8 hSpCas9 negative selection 11750188
182586233 182586256 1 - 28162770 HEL viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 1.0091024845435113 [210] [271] 8 hSpCas9 negative selection 11750189
182585776 182585799 1 - 28162770 HEL viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 -0.13570339814200832 [246] [143] -1 hSpCas9 negative selection 11750190
182585661 182585684 1 - 28162770 HEL viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 0.02747773074616211 [408] [266] 0 hSpCas9 negative selection 11750191
182586302 182586325 1 - 28162770 MV411 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 -0.11784691329896901 [75] [58] -1 hSpCas9 negative selection 11919548
182585617 182585640 1 - 28162770 MV411 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 0.7721649443705614 [537] [773] 7 hSpCas9 negative selection 11919549
182585846 182585869 1 + 28162770 MV411 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 -0.4152472453628986 [428] [270] -3 hSpCas9 negative selection 11919550
182585723 182585746 1 + 28162770 MV411 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.1095969093678204 [427] [388] 0 hSpCas9 negative selection 11919551
182585598 182585621 1 - 28162770 MV411 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 0.9609147920266117 [160] [263] 8 hSpCas9 negative selection 11919552
182586754 182586777 1 - 28162770 MV411 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.3612410189121884 [275] [180] -3 hSpCas9 negative selection 11919553
182586329 182586352 1 - 28162770 MV411 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 -0.9541963103868754 [68] [29] -6 hSpCas9 negative selection 11919554
182586233 182586256 1 - 28162770 MV411 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 0.8324000515039315 [209] [314] 7 hSpCas9 negative selection 11919555
182585776 182585799 1 - 28162770 MV411 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 -0.10899339150452633 [200] [156] -1 hSpCas9 negative selection 11919556
182585661 182585684 1 - 28162770 MV411 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 -0.1321511124917787 [401] [308] -1 hSpCas9 negative selection 11919557
182586302 182586325 1 - 28162770 MONOMAC1 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 -0.286304185156641 [49] [46] -3 hSpCas9 negative selection 12088914
182585617 182585640 1 - 28162770 MONOMAC1 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 -0.042763579989676614 [380] [423] 0 hSpCas9 negative selection 12088915
182585846 182585869 1 + 28162770 MONOMAC1 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 0.6062712419353484 [254] [444] 6 hSpCas9 negative selection 12088916
182585723 182585746 1 + 28162770 MONOMAC1 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.13028450659802715 [266] [334] 1 hSpCas9 negative selection 12088917
182585598 182585621 1 - 28162770 MONOMAC1 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 0.3253841875928898 [109] [157] 3 hSpCas9 negative selection 12088918
182586754 182586777 1 - 28162770 MONOMAC1 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 0.2160706251208906 [186] [248] 2 hSpCas9 negative selection 12088919
182586329 182586352 1 - 28162770 MONOMAC1 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 -0.2459464475405002 [59] [57] -2 hSpCas9 negative selection 12088920
182586233 182586256 1 - 28162770 MONOMAC1 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 0.8160193057658929 [164] [332] 7 hSpCas9 negative selection 12088921
182585776 182585799 1 - 28162770 MONOMAC1 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 -0.3992256976728204 [129] [112] -3 hSpCas9 negative selection 12088922
182585661 182585684 1 - 28162770 MONOMAC1 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 -0.5622431903863913 [312] [242] -5 hSpCas9 negative selection 12088923
182586302 182586325 1 - 28162770 OCIAML2 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 -0.8856673245210049 [21] [65] -6 hSpCas9 negative selection 12258280
182585617 182585640 1 - 28162770 OCIAML2 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 0.5830081383599117 [98] [821] 5 hSpCas9 negative selection 12258281
182585846 182585869 1 + 28162770 OCIAML2 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 0.06897214207911939 [69] [406] 0 hSpCas9 negative selection 12258282
182585723 182585746 1 + 28162770 OCIAML2 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 -0.3515771535983976 [92] [403] -3 hSpCas9 negative selection 12258283
182585598 182585621 1 - 28162770 OCIAML2 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 -0.281968261218263 [33] [154] -2 hSpCas9 negative selection 12258284
182586754 182586777 1 - 28162770 OCIAML2 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.9188341884562043 [43] [128] -6 hSpCas9 negative selection 12258285
182586329 182586352 1 - 28162770 OCIAML2 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 -0.6446592250172098 [10] [38] -5 hSpCas9 negative selection 12258286
182586233 182586256 1 - 28162770 OCIAML2 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 1.1757332201431385 [22] [287] 9 hSpCas9 negative selection 12258287
182585776 182585799 1 - 28162770 OCIAML2 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 -0.15747193998253095 [32] [163] -1 hSpCas9 negative selection 12258288
182585661 182585684 1 - 28162770 OCIAML2 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 0.2785620712573045 [46] [315] 2 hSpCas9 negative selection 12258289
182586302 182586325 1 - 28162770 OCIAML3 viability AGAGCGGCTGAGGAAAGGAGGGG RNASEL ENSG00000135828 -1.1414954356266562 [18] [25] -7 hSpCas9 negative selection 12427646
182585617 182585640 1 - 28162770 OCIAML3 viability GCTGTGAAGACGTTCTGTGAGGG RNASEL ENSG00000135828 0.1792214978288147 [164] [563] 1 hSpCas9 negative selection 12427647
182585846 182585869 1 + 28162770 OCIAML3 viability GAAGAACCTTCACAAGGGAATGG RNASEL ENSG00000135828 0.20972696605474384 [113] [397] 2 hSpCas9 negative selection 12427648
182585723 182585746 1 + 28162770 OCIAML3 viability TGAGTTTGCCAATCATAGGGCGG RNASEL ENSG00000135828 0.405992359675837 [123] [495] 4 hSpCas9 negative selection 12427649
182585598 182585621 1 - 28162770 OCIAML3 viability AGGGCAGCCCACGTGCACAGCGG RNASEL ENSG00000135828 -0.16401979957934787 [35] [96] -1 hSpCas9 negative selection 12427650
182586754 182586777 1 - 28162770 OCIAML3 viability GAGGGACCCACGTCCTCCAGCGG RNASEL ENSG00000135828 -0.447166251994892 [55] [123] -3 hSpCas9 negative selection 12427651
182586329 182586352 1 - 28162770 OCIAML3 viability TTTGAGGCGAAAGACAAAGGAGG RNASEL ENSG00000135828 -1.1896173852448277 [33] [44] -7 hSpCas9 negative selection 12427652
182586233 182586256 1 - 28162770 OCIAML3 viability GAAGATTCTCCTTGATGAGATGG RNASEL ENSG00000135828 -0.10302128781202069 [73] [207] -1 hSpCas9 negative selection 12427653
182585776 182585799 1 - 28162770 OCIAML3 viability AAGCCTCAGAGCTCACACTGGGG RNASEL ENSG00000135828 0.5477663208040002 [45] [202] 5 hSpCas9 negative selection 12427654
182585661 182585684 1 - 28162770 OCIAML3 viability CAGAAGGAGGCATCTACCTGGGG RNASEL ENSG00000135828 -0.7548038522272192 [127] [228] -5 hSpCas9 negative selection 12427655