Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 27246
• Symbol: RNF115
• Description: ring finger protein 115

DataSource: http://genomecrispr.dkfz.de/#!/results/RNF115

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
145747987	145748010	1	+	26472758	Jiyoye	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	0.07460004241900287	[67]	[53]	0	hSpCas9	negative selection	137850
145751470	145751493	1	-	26472758	Jiyoye	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	5.107615099646965	[0]	[25]	9	hSpCas9	negative selection	137851
145823814	145823837	1	+	26472758	Jiyoye	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	0.49737319047745154	[92]	[98]	4	hSpCas9	negative selection	137852
145751482	145751505	1	-	26472758	Jiyoye	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	-0.5142147837977602	[124]	[65]	-4	hSpCas9	negative selection	137853
145771852	145771875	1	+	26472758	Jiyoye	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	0.29865092472770444	[137]	[127]	2	hSpCas9	negative selection	137854
145771747	145771770	1	-	26472758	Jiyoye	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	0.9989915532680922	[139]	[210]	6	hSpCas9	negative selection	137855
145752986	145753009	1	+	26472758	Jiyoye	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	-0.1777871192152826	[104]	[69]	-1	hSpCas9	negative selection	137856
145750406	145750429	1	-	26472758	Jiyoye	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	1.179764885402801	[23]	[40]	7	hSpCas9	negative selection	137857
145748004	145748027	1	-	26472758	Jiyoye	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	-1.0206861581305542	[225]	[83]	-6	hSpCas9	negative selection	137858
145771779	145771802	1	-	26472758	Jiyoye	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	1.223729240409942	[133]	[235]	7	hSpCas9	negative selection	137859
145747987	145748010	1	+	26472758	KBM7	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	-0.4340604944925974	[187,183]	[55,72]	-4	hSpCas9	negative selection	328968
145751470	145751493	1	-	26472758	KBM7	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	0.1691136328119509	[120,146]	[73,69]	1	hSpCas9	negative selection	328969
145823814	145823837	1	+	26472758	KBM7	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	-0.5504274099979514	[515,257]	[108,130]	-5	hSpCas9	negative selection	328970
145751482	145751505	1	-	26472758	KBM7	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	-0.20913665141485693	[581,335]	[229,139]	-2	hSpCas9	negative selection	328971
145771852	145771875	1	+	26472758	KBM7	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	-0.4243691033079333	[911,737]	[346,233]	-4	hSpCas9	negative selection	328972
145771747	145771770	1	-	26472758	KBM7	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	-0.12153409851509611	[783,469]	[248,279]	-1	hSpCas9	negative selection	328973
145752986	145753009	1	+	26472758	KBM7	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	-0.4109527240586142	[671,635]	[141,311]	-4	hSpCas9	negative selection	328974
145750406	145750429	1	-	26472758	KBM7	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	-1.1172806283849974	[345,657]	[78,142]	-7	hSpCas9	negative selection	328975
145748004	145748027	1	-	26472758	KBM7	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	-0.20889288845601775	[602,365]	[152,228]	-2	hSpCas9	negative selection	328976
145771779	145771802	1	-	26472758	KBM7	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	0.04198760184437944	[1201,933]	[571,459]	0	hSpCas9	negative selection	328977
145747987	145748010	1	+	26472758	Raji	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	0.08501572234514498	[129]	[31]	0	hSpCas9	negative selection	520086
145751470	145751493	1	-	26472758	Raji	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	0.2678482075668456	[67]	[18]	2	hSpCas9	negative selection	520087
145823814	145823837	1	+	26472758	Raji	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	0.25938662881864943	[215]	[59]	2	hSpCas9	negative selection	520088
145751482	145751505	1	-	26472758	Raji	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	0.3860995634396629	[121]	[36]	3	hSpCas9	negative selection	520089
145771852	145771875	1	+	26472758	Raji	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	-0.2369123725422173	[324]	[63]	-2	hSpCas9	negative selection	520090
145771747	145771770	1	-	26472758	Raji	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	-0.46752530068363374	[285]	[47]	-4	hSpCas9	negative selection	520091
145752986	145753009	1	+	26472758	Raji	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	0.12438996067928923	[252]	[63]	1	hSpCas9	negative selection	520092
145750406	145750429	1	-	26472758	Raji	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	-1.0951724703086796	[312]	[33]	-7	hSpCas9	negative selection	520093
145748004	145748027	1	-	26472758	Raji	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	0.9170523232694502	[266]	[116]	8	hSpCas9	negative selection	520094
145771779	145771802	1	-	26472758	Raji	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.6453650560335342	[673]	[99]	-5	hSpCas9	negative selection	520095
145747987	145748010	1	+	26472758	K562	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	0.30229964374694673	[170]	[177]	2	hSpCas9	negative selection	711204
145751470	145751493	1	-	26472758	K562	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	1.3278347358540843	[83]	[177]	9	hSpCas9	negative selection	711205
145823814	145823837	1	+	26472758	K562	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	0.992546428119953	[308]	[518]	8	hSpCas9	negative selection	711206
145751482	145751505	1	-	26472758	K562	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	-0.4059197819067334	[236]	[150]	-3	hSpCas9	negative selection	711207
145771852	145771875	1	+	26472758	K562	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	0.20430414037507993	[546]	[531]	1	hSpCas9	negative selection	711208
145771747	145771770	1	-	26472758	K562	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	0.5721969118349359	[442]	[555]	4	hSpCas9	negative selection	711209
145752986	145753009	1	+	26472758	K562	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	0.7814865382832916	[489]	[710]	6	hSpCas9	negative selection	711210
145750406	145750429	1	-	26472758	K562	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	0.1249284477398876	[389]	[358]	0	hSpCas9	negative selection	711211
145748004	145748027	1	-	26472758	K562	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	0.4750824111436137	[322]	[378]	4	hSpCas9	negative selection	711212
145771779	145771802	1	-	26472758	K562	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.4327217053116771	[928]	[580]	-3	hSpCas9	negative selection	711213
145771851	145771874	1	+	26627737	DLD1	viability	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.678176221436844	[561]	[245,323,275]	6	hSpCas9	negative selection	765627
145771834	145771857	1	+	26627737	DLD1	viability	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	2.4401544311035175	[5]	[17,0,10]	9	hSpCas9	negative selection	765628
145751505	145751528	1	-	26627737	DLD1	viability	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	0.3738253048021477	[387]	[174,157,140]	4	hSpCas9	negative selection	765629
145751504	145751527	1	-	26627737	DLD1	viability	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	-0.7350581864116813	[319]	[27,123,34]	-6	hSpCas9	negative selection	765630
145747994	145748017	1	-	26627737	DLD1	viability	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	-0.15938997078723247	[586]	[117,194,178]	-2	hSpCas9	negative selection	765631
145746875	145746898	1	-	26627737	DLD1	viability	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	0.48589727938640004	[431]	[143,192,224]	5	hSpCas9	negative selection	765632
145771851	145771874	1	+	26627737	GBM cells	viability after 5 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.13549473910110021	[476]	[253,307]	2	hSpCas9	negative selection	847942
145771834	145771857	1	+	26627737	GBM cells	viability after 5 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	-0.10108612511431492	[11]	[4,6]	-2	hSpCas9	negative selection	847943
145751505	145751528	1	-	26627737	GBM cells	viability after 5 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.09345280021188718	[376]	[174,203]	-1	hSpCas9	negative selection	847944
145751504	145751527	1	-	26627737	GBM cells	viability after 5 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	0.6144604854169861	[189]	[139,171]	8	hSpCas9	negative selection	847945
145747994	145748017	1	-	26627737	GBM cells	viability after 5 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	1.6107884880890613	[115]	[175,203]	9	hSpCas9	negative selection	847946
145746875	145746898	1	-	26627737	GBM cells	viability after 5 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	0.1067187599990872	[354]	[275,133]	1	hSpCas9	negative selection	847947
145771851	145771874	1	+	26627737	GBM cells	viability after 13 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.48213884876717505	[476]	[339,378]	6	hSpCas9	negative selection	930257
145771834	145771857	1	+	26627737	GBM cells	viability after 13 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	-0.7404736689424869	[11]	[4,2]	-7	hSpCas9	negative selection	930258
145751505	145751528	1	-	26627737	GBM cells	viability after 13 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	0.21613594022474503	[376]	[289,194]	2	hSpCas9	negative selection	930259
145751504	145751527	1	-	26627737	GBM cells	viability after 13 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	0.841792901649125	[189]	[272,112]	8	hSpCas9	negative selection	930260
145747994	145748017	1	-	26627737	GBM cells	viability after 13 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	1.3358036721119726	[115]	[170,148]	9	hSpCas9	negative selection	930261
145746875	145746898	1	-	26627737	GBM cells	viability after 13 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-0.45047221550842326	[354]	[194,96]	-5	hSpCas9	negative selection	930262
145771851	145771874	1	+	26627737	GBM cells	viability after 21 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.6942268635691743	[476]	[423,414]	7	hSpCas9	negative selection	1012572
145771834	145771857	1	+	26627737	GBM cells	viability after 21 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	-0.02916415160343533	[11]	[8,3]	0	hSpCas9	negative selection	1012573
145751505	145751528	1	-	26627737	GBM cells	viability after 21 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	0.4675466433450526	[376]	[289,276]	5	hSpCas9	negative selection	1012574
145751504	145751527	1	-	26627737	GBM cells	viability after 21 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	-0.10850543650290279	[189]	[89,100]	-1	hSpCas9	negative selection	1012575
145747994	145748017	1	-	26627737	GBM cells	viability after 21 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	1.434845672664132	[115]	[184,156]	9	hSpCas9	negative selection	1012576
145746875	145746898	1	-	26627737	GBM cells	viability after 21 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-1.0244576784282442	[354]	[110,79]	-7	hSpCas9	negative selection	1012577
145771851	145771874	1	+	26627737	RPE1	viability after 9 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.8488164033117582	[1121]	[667,586]	5	hSpCas9	negative selection	1094887
145771834	145771857	1	+	26627737	RPE1	viability after 9 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	0.5436213188074	[9]	[4,3]	3	hSpCas9	negative selection	1094888
145751505	145751528	1	-	26627737	RPE1	viability after 9 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	0.04696000952555007	[981]	[307,329]	0	hSpCas9	negative selection	1094889
145751504	145751527	1	-	26627737	RPE1	viability after 9 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	-0.09480881250452333	[763]	[116,361]	0	hSpCas9	negative selection	1094890
145747994	145748017	1	-	26627737	RPE1	viability after 9 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.8093719866874989	[855]	[411,543]	5	hSpCas9	negative selection	1094891
145746875	145746898	1	-	26627737	RPE1	viability after 9 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-0.6105328095726543	[1346]	[218,349]	-4	hSpCas9	negative selection	1094892
145771851	145771874	1	+	26627737	RPE1	viability after 12 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	1.193451939544252	[1121]	[702,674]	7	hSpCas9	negative selection	1177202
145771834	145771857	1	+	26627737	RPE1	viability after 12 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	-0.09566808152189399	[9]	[2,1]	0	hSpCas9	negative selection	1177203
145751505	145751528	1	-	26627737	RPE1	viability after 12 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	0.3720929007363529	[981]	[356,324]	2	hSpCas9	negative selection	1177204
145751504	145751527	1	-	26627737	RPE1	viability after 12 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	-0.02637457288132558	[763]	[219,181]	0	hSpCas9	negative selection	1177205
145747994	145748017	1	-	26627737	RPE1	viability after 12 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.7363830251188608	[855]	[353,413]	5	hSpCas9	negative selection	1177206
145746875	145746898	1	-	26627737	RPE1	viability after 12 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-0.6683417318562976	[1346]	[149,309]	-4	hSpCas9	negative selection	1177207
145771851	145771874	1	+	26627737	RPE1	viability after 15 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	1.1911707308504451	[1121]	[627,817]	6	hSpCas9	negative selection	1259517
145771834	145771857	1	+	26627737	RPE1	viability after 15 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	-0.1626683099235846	[9]	[0,3]	-1	hSpCas9	negative selection	1259518
145751505	145751528	1	-	26627737	RPE1	viability after 15 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	0.24905554824189868	[981]	[350,309]	1	hSpCas9	negative selection	1259519
145751504	145751527	1	-	26627737	RPE1	viability after 15 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	-0.048180273219514784	[763]	[235,182]	0	hSpCas9	negative selection	1259520
145747994	145748017	1	-	26627737	RPE1	viability after 15 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.6922246580183342	[855]	[320,458]	4	hSpCas9	negative selection	1259521
145746875	145746898	1	-	26627737	RPE1	viability after 15 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-0.16019562065118764	[1346]	[228,448]	-1	hSpCas9	negative selection	1259522
145771851	145771874	1	+	26627737	RPE1	viability after 18 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	1.2742115227872177	[1121]	[698,767]	7	hSpCas9	negative selection	1341832
145771834	145771857	1	+	26627737	RPE1	viability after 18 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	-0.456391497259518	[9]	[0,2]	-3	hSpCas9	negative selection	1341833
145751505	145751528	1	-	26627737	RPE1	viability after 18 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	0.4004794341445199	[981]	[343,355]	2	hSpCas9	negative selection	1341834
145751504	145751527	1	-	26627737	RPE1	viability after 18 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	0.20253973296329567	[763]	[200,275]	1	hSpCas9	negative selection	1341835
145747994	145748017	1	-	26627737	RPE1	viability after 18 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	1.0567575278538204	[855]	[350,618]	6	hSpCas9	negative selection	1341836
145746875	145746898	1	-	26627737	RPE1	viability after 18 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-0.5781019532186958	[1346]	[155,336]	-4	hSpCas9	negative selection	1341837
145771851	145771874	1	+	26627737	HeLa	viability after 8 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.5071746196037038	[559]	[534,250,297]	4	hSpCas9	negative selection	1424147
145771834	145771857	1	+	26627737	HeLa	viability after 8 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	1.634071009003188	[0]	[0,1,0]	9	hSpCas9	negative selection	1424148
145751505	145751528	1	-	26627737	HeLa	viability after 8 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.8451769645958087	[572]	[164,145,112]	-7	hSpCas9	negative selection	1424149
145751504	145751527	1	-	26627737	HeLa	viability after 8 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	-1.7010127679307805	[382]	[105,25,34]	-9	hSpCas9	negative selection	1424150
145747994	145748017	1	-	26627737	HeLa	viability after 8 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.12033765166795724	[500]	[212,364,134]	1	hSpCas9	negative selection	1424151
145746875	145746898	1	-	26627737	HeLa	viability after 8 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-0.8561972289498203	[577]	[344,49,71]	-7	hSpCas9	negative selection	1424152
145771851	145771874	1	+	26627737	HeLa	viability after 12 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.816393121352606	[559]	[610,374,245]	6	hSpCas9	negative selection	1506462
145771834	145771857	1	+	26627737	HeLa	viability after 12 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	4.364015922614607	[0]	[2,11,9]	9	hSpCas9	negative selection	1506463
145751505	145751528	1	-	26627737	HeLa	viability after 12 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.8218706175557339	[572]	[75,182,135]	-6	hSpCas9	negative selection	1506464
145751504	145751527	1	-	26627737	HeLa	viability after 12 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	-2.1219547579655926	[382]	[8,57,38]	-9	hSpCas9	negative selection	1506465
145747994	145748017	1	-	26627737	HeLa	viability after 12 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.34566657409781004	[500]	[331,265,192]	3	hSpCas9	negative selection	1506466
145746875	145746898	1	-	26627737	HeLa	viability after 12 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-2.1087756911079616	[577]	[9,81,69]	-9	hSpCas9	negative selection	1506467
145771851	145771874	1	+	26627737	HeLa	viability after 15 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.6209306857842535	[559]	[454,358,226]	5	hSpCas9	negative selection	1588777
145771834	145771857	1	+	26627737	HeLa	viability after 15 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	5.199814401469478	[0]	[0,41,0]	9	hSpCas9	negative selection	1588778
145751505	145751528	1	-	26627737	HeLa	viability after 15 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.5390625457871507	[572]	[200,156,119]	-5	hSpCas9	negative selection	1588779
145751504	145751527	1	-	26627737	HeLa	viability after 15 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	-1.3445234947535596	[382]	[92,50,37]	-8	hSpCas9	negative selection	1588780
145747994	145748017	1	-	26627737	HeLa	viability after 15 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	-0.19673444100361684	[500]	[112,191,233]	-2	hSpCas9	negative selection	1588781
145746875	145746898	1	-	26627737	HeLa	viability after 15 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-0.8001888971575729	[577]	[185,176,33]	-6	hSpCas9	negative selection	1588782
145771851	145771874	1	+	26627737	HeLa	viability after 18 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.6583109540937152	[559]	[324,294,226]	5	hSpCas9	negative selection	1671092
145771834	145771857	1	+	26627737	HeLa	viability after 18 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	5.224748165617404	[0]	[0,34,0]	9	hSpCas9	negative selection	1671093
145751505	145751528	1	-	26627737	HeLa	viability after 18 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.464623619602063	[572]	[140,142,119]	-4	hSpCas9	negative selection	1671094
145751504	145751527	1	-	26627737	HeLa	viability after 18 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	-1.3662295379190816	[382]	[59,42,37]	-8	hSpCas9	negative selection	1671095
145747994	145748017	1	-	26627737	HeLa	viability after 18 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	-0.22028191079835374	[500]	[74,152,233]	-2	hSpCas9	negative selection	1671096
145746875	145746898	1	-	26627737	HeLa	viability after 18 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-0.7732639314696027	[577]	[122,154,33]	-6	hSpCas9	negative selection	1671097
145771851	145771874	1	+	26627737	HCT116	viability after 6 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	-1.3525340024046968	[1173]	[157,24]	-6	hSpCas9	negative selection	1753407
145771834	145771857	1	+	26627737	HCT116	viability after 6 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	3.1429179229026296	[1]	[5,0]	9	hSpCas9	negative selection	1753408
145751505	145751528	1	-	26627737	HCT116	viability after 6 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	0.8886996606525186	[694]	[35,293]	5	hSpCas9	negative selection	1753409
145751504	145751527	1	-	26627737	HCT116	viability after 6 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	2.477052090874963	[303]	[180,312]	9	hSpCas9	negative selection	1753410
145747994	145748017	1	-	26627737	HCT116	viability after 6 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.049059862184850866	[788]	[166,106]	0	hSpCas9	negative selection	1753411
145746875	145746898	1	-	26627737	HCT116	viability after 6 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	0.2268382715102285	[1019]	[128,219]	1	hSpCas9	negative selection	1753412
145771851	145771874	1	+	26627737	HCT116	viability after 8 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	-0.3645095582283241	[683]	[281,297,297]	-4	hSpCas9	negative selection	1835722
145771834	145771857	1	+	26627737	HCT116	viability after 8 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	1.141128492458952	[2]	[5,2,1]	8	hSpCas9	negative selection	1835723
145751505	145751528	1	-	26627737	HCT116	viability after 8 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.13920425524049812	[448]	[236,279,157]	-1	hSpCas9	negative selection	1835724
145751504	145751527	1	-	26627737	HCT116	viability after 8 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	-0.5196745211048737	[165]	[85,57,47]	-6	hSpCas9	negative selection	1835725
145747994	145748017	1	-	26627737	HCT116	viability after 8 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.2733822126373932	[296]	[198,161,231]	3	hSpCas9	negative selection	1835726
145746875	145746898	1	-	26627737	HCT116	viability after 8 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-0.09676945213185922	[383]	[141,202,246]	-1	hSpCas9	negative selection	1835727
145771851	145771874	1	+	26627737	HCT116	viability after 9 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	-0.07790776095581786	[1173]	[482,149]	0	hSpCas9	negative selection	1918037
145771834	145771857	1	+	26627737	HCT116	viability after 9 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	2.817933077084245	[1]	[5,1]	9	hSpCas9	negative selection	1918038
145751505	145751528	1	-	26627737	HCT116	viability after 9 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	0.376254755210607	[694]	[284,205]	3	hSpCas9	negative selection	1918039
145751504	145751527	1	-	26627737	HCT116	viability after 9 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	1.574528459911864	[303]	[181,288]	8	hSpCas9	negative selection	1918040
145747994	145748017	1	-	26627737	HCT116	viability after 9 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.31438249169758004	[788]	[266,257]	2	hSpCas9	negative selection	1918041
145746875	145746898	1	-	26627737	HCT116	viability after 9 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-0.20506932834867042	[1019]	[371,128]	-1	hSpCas9	negative selection	1918042
145771851	145771874	1	+	26627737	HCT116	viability after 12 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	-0.4237112032120145	[683]	[209,307,291]	-4	hSpCas9	negative selection	2000352
145771834	145771857	1	+	26627737	HCT116	viability after 12 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	1.6522339191197348	[2]	[3,6,3]	9	hSpCas9	negative selection	2000353
145751505	145751528	1	-	26627737	HCT116	viability after 12 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.801900420725685	[448]	[91,182,135]	-7	hSpCas9	negative selection	2000354
145751504	145751527	1	-	26627737	HCT116	viability after 12 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	0.28508192509602037	[165]	[164,75,71]	3	hSpCas9	negative selection	2000355
145747994	145748017	1	-	26627737	HCT116	viability after 12 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.14597537254512133	[296]	[222,61,225]	1	hSpCas9	negative selection	2000356
145746875	145746898	1	-	26627737	HCT116	viability after 12 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-0.10357097644148139	[383]	[143,215,207]	-1	hSpCas9	negative selection	2000357
145771851	145771874	1	+	26627737	HCT116	viability after 15 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	-0.17368151329359116	[683]	[365,336,343]	-2	hSpCas9	negative selection	2082667
145771834	145771857	1	+	26627737	HCT116	viability after 15 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	0.8420438028302382	[2]	[0,3,3]	7	hSpCas9	negative selection	2082668
145751505	145751528	1	-	26627737	HCT116	viability after 15 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.41388967130227183	[448]	[183,161,232]	-4	hSpCas9	negative selection	2082669
145751504	145751527	1	-	26627737	HCT116	viability after 15 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	1.0770026740000738	[165]	[351,91,177]	8	hSpCas9	negative selection	2082670
145747994	145748017	1	-	26627737	HCT116	viability after 15 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	-0.13572479513176375	[296]	[223,84,164]	-1	hSpCas9	negative selection	2082671
145746875	145746898	1	-	26627737	HCT116	viability after 15 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	0.12377226349527432	[383]	[256,234,230]	1	hSpCas9	negative selection	2082672
145771851	145771874	1	+	26627737	HCT116	viability after 18 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	-0.4787069067429568	[683]	[190,246,274]	-4	hSpCas9	negative selection	2164982
145771834	145771857	1	+	26627737	HCT116	viability after 18 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	-0.14026996347035325	[2]	[0,0,1]	-1	hSpCas9	negative selection	2164983
145751505	145751528	1	-	26627737	HCT116	viability after 18 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.6581929369762699	[448]	[122,131,158]	-6	hSpCas9	negative selection	2164984
145751504	145751527	1	-	26627737	HCT116	viability after 18 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	0.5399954375540481	[165]	[177,91,79]	4	hSpCas9	negative selection	2164985
145747994	145748017	1	-	26627737	HCT116	viability after 18 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.06506830155939052	[296]	[163,89,202]	0	hSpCas9	negative selection	2164986
145746875	145746898	1	-	26627737	HCT116	viability after 18 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	0.2807936599292263	[383]	[227,203,246]	2	hSpCas9	negative selection	2164987
145787530	145787553	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCCCAGGCTGGAGTGCAAGGG	RNF115	ENSG00000265491	-0.29783996533031276	[705,290]	[109,64]	-1	dCas9-VP64	positive selection	2393674
145824057	145824080	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCGCCTCCCAGCACCAAAGAGG	RNF115	ENSG00000265491	1.1447909361983681	[0,4]	[0,1]	4	dCas9-VP64	positive selection	2440096
145824034	145824057	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGCGCCAACAGCTACCCTGCGG	RNF115	ENSG00000265491	2.254680514055491	[1,19]	[0,23]	7	dCas9-VP64	positive selection	2440097
145766104	145766127	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAGGTCTCTGGTTTTCCTAGG	RNF115	ENSG00000265491	-0.5546278987425284	[99,97]	[19,8]	-3	dCas9-VP64	positive selection	2462252
145787530	145787553	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCCCAGGCTGGAGTGCAAGGG	RNF115	ENSG00000265491	-0.2409913144319511	[429,255]	[120,70]	-2	dCas9-VP64	positive selection	2488929
145824057	145824080	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCGCCTCCCAGCACCAAAGAGG	RNF115	ENSG00000265491	1.41039570385198	[1,31]	[3,23]	7	dCas9-VP64	positive selection	2535351
145824034	145824057	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGCGCCAACAGCTACCCTGCGG	RNF115	ENSG00000265491	-0.5834445452003956	[30,3]	[3,1]	-6	dCas9-VP64	positive selection	2535352
145766104	145766127	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAGGTCTCTGGTTTTCCTAGG	RNF115	ENSG00000265491	1.5607946270683937	[160,198]	[146,197]	8	dCas9-VP64	positive selection	2557507
145823803	145823826	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAAGTGGCAGAAAAACCGGTGGG	RNF115	ENSG00000265491	0.47425382410030903	[2,2]	[2,3]	8	hSpCas9	positive selection	3017129
145771710	145771733	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAGATCTCCAGCTATTGAAGGG	RNF115	ENSG00000265491	-0.20021751552892295	[3,3]	[3,1]	-3	hSpCas9	positive selection	3017130
145771853	145771876	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	0.4260032817393357	[2,2]	[2,3]	8	hSpCas9	positive selection	3017131
145771779	145771802	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	0.34643765504622803	[2,1]	[2,2]	7	hSpCas9	positive selection	3017132
145823803	145823826	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAAGTGGCAGAAAAACCGGTGGG	RNF115	ENSG00000265491	-0.7489843899571559	[2,2]	[0,0]	-8	hSpCas9	positive selection	3084987
145771710	145771733	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAGATCTCCAGCTATTGAAGGG	RNF115	ENSG00000265491	-0.7400864950861203	[3,3]	[2,0]	-8	hSpCas9	positive selection	3084988
145771853	145771876	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	0.6749030008073398	[2,2]	[0,4]	9	hSpCas9	positive selection	3084989
145771779	145771802	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.8984059165549344	[2,2]	[0,0]	-9	hSpCas9	positive selection	3084990
145788907	145788930		-	24336571	A375	resistance to PLX after 7 days	AAGAAGTGACAGATGATTCCAGG	RNF115	ENSG00000265491	0.14421741808309774	[19,22]	[23,23]	4	hSpCas9	positive selection	3141187
145788931	145788954		+	24336571	A375	resistance to PLX after 7 days	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.23146381972270302	[10,8]	[9,6]	-7	hSpCas9	positive selection	3141188
145788938	145788961		-	24336571	A375	resistance to PLX after 7 days	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.27567523863412874	[15,17]	[21,19]	7	hSpCas9	positive selection	3141189
145750445	145750468		+	24336571	A375	resistance to PLX after 7 days	GTGATCTTTTCCTTGTCAGCTGG	RNF115	ENSG00000265491	0.35662479837142935	[15,15]	[18,21]	8	hSpCas9	positive selection	3141190
145750416	145750439		-	24336571	A375	resistance to PLX after 7 days	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.2586337359851305	[23,23]	[25,30]	7	hSpCas9	positive selection	3141191
145750485	145750508		-	24336571	A375	resistance to PLX after 7 days	TTTGTAGCTTTTAGGACAACTGG	RNF115	ENSG00000265491	-0.29842482460510045	[12,9]	[7,10]	-8	hSpCas9	positive selection	3141192
145788907	145788930		-	24336571	A375	resistance to PLX after 14 days	AAGAAGTGACAGATGATTCCAGG	RNF115	ENSG00000265491	-0.4220792321107244	[26,25]	[9,7]	-5	hSpCas9	positive selection	3198980
145788931	145788954		+	24336571	A375	resistance to PLX after 14 days	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.43900460031331745	[8,9]	[5,5]	4	hSpCas9	positive selection	3198981
145788938	145788961		-	24336571	A375	resistance to PLX after 14 days	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.1181554340420331	[15,20]	[7,9]	1	hSpCas9	positive selection	3198982
145750445	145750468		+	24336571	A375	resistance to PLX after 14 days	GTGATCTTTTCCTTGTCAGCTGG	RNF115	ENSG00000265491	1.305588003551888	[20,18]	[25,19]	8	hSpCas9	positive selection	3198983
145750416	145750439		-	24336571	A375	resistance to PLX after 14 days	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.9337321055411215	[30,18]	[23,19]	7	hSpCas9	positive selection	3198984
145750485	145750508		-	24336571	A375	resistance to PLX after 14 days	TTTGTAGCTTTTAGGACAACTGG	RNF115	ENSG00000265491	-0.0021264139078556177	[6,9]	[3,2]	0	hSpCas9	positive selection	3198985
145788907	145788930		-	24336571	A375	viability after 7 days	AAGAAGTGACAGATGATTCCAGG	RNF115	ENSG00000265491	0.2577204366538716	[18]	[19,22]	4	hSpCas9	negative selection	3256773
145788931	145788954		+	24336571	A375	viability after 7 days	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.2759944624909497	[8]	[10,8]	4	hSpCas9	negative selection	3256774
145788938	145788961		-	24336571	A375	viability after 7 days	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.1910080349528933	[15]	[15,17]	3	hSpCas9	negative selection	3256775
145750445	145750468		+	24336571	A375	viability after 7 days	GTGATCTTTTCCTTGTCAGCTGG	RNF115	ENSG00000265491	0.24186452175792977	[13]	[15,15]	3	hSpCas9	negative selection	3256776
145750416	145750439		-	24336571	A375	viability after 7 days	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.4285796644956322	[18]	[23,23]	6	hSpCas9	negative selection	3256777
145750485	145750508		-	24336571	A375	viability after 7 days	TTTGTAGCTTTTAGGACAACTGG	RNF115	ENSG00000265491	0.6094416194987881	[7]	[12,9]	8	hSpCas9	negative selection	3256778
145788907	145788930		-	24336571	A375	viability after 14 days	AAGAAGTGACAGATGATTCCAGG	RNF115	ENSG00000265491	0.5707930988893504	[18]	[26,25]	7	hSpCas9	negative selection	3314566
145788931	145788954		+	24336571	A375	viability after 14 days	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.28406761101398526	[8]	[8,9]	3	hSpCas9	negative selection	3314567
145788938	145788961		-	24336571	A375	viability after 14 days	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.2919615900097123	[15]	[15,20]	4	hSpCas9	negative selection	3314568
145750445	145750468		+	24336571	A375	viability after 14 days	GTGATCTTTTCCTTGTCAGCTGG	RNF115	ENSG00000265491	0.565657070639886	[13]	[20,18]	7	hSpCas9	negative selection	3314569
145750416	145750439		-	24336571	A375	viability after 14 days	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.4783524246204089	[18]	[30,18]	6	hSpCas9	negative selection	3314570
145750485	145750508		-	24336571	A375	viability after 14 days	TTTGTAGCTTTTAGGACAACTGG	RNF115	ENSG00000265491	0.23384953724005908	[7]	[6,9]	3	hSpCas9	negative selection	3314571
145788931	145788954	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.17730201619088934	[172,172]	[0,0]	-1	hSpCas9	positive selection	3390056
145750416	145750439	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.45642631152553037	[222,222]	[1,1]	2	hSpCas9	positive selection	3390057
145750455	145750478	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	-0.12637808102821713	[166,166]	[0,0]	0	hSpCas9	positive selection	3390058
145823802	145823825	1	+	26780180	HT29	viability (Avana library 4 designs)	AAAGTGGCAGAAAAACCGGTGGG	RNF115	ENSG00000265491	3.59747565807266	[]	[]	9	hSpCas9	negative selection	3455500
145771710	145771733	1	-	26780180	HT29	viability (Avana library 4 designs)	ACAGATCTCCAGCTATTGAAGGG	RNF115	ENSG00000265491	1.1201900244687	[]	[]	4	hSpCas9	negative selection	3455501
145771852	145771875	1	+	26780180	HT29	viability (Avana library 4 designs)	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	0.665892210907101	[]	[]	2	hSpCas9	negative selection	3455502
145771779	145771802	1	-	26780180	HT29	viability (Avana library 4 designs)	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	1.70566273774185	[]	[]	6	hSpCas9	negative selection	3455503
145771710	145771733	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGATCTCCAGCTATTGAAGGG	RNF115	ENSG00000265491	-6.38725003960228	[]	[]	-6	hSpCas9	negative selection	3553520
145823802	145823825	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAAGTGGCAGAAAAACCGGTGGG	RNF115	ENSG00000265491	-15.880145352329	[]	[]	-9	hSpCas9	negative selection	3553521
145771779	145771802	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-3.43722021277236	[]	[]	-4	hSpCas9	negative selection	3553522
145771852	145771875	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	-7.24012911031626	[]	[]	-6	hSpCas9	negative selection	3553523
145823762	145823785	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCTCTTACCGGTAGTTTGGGG	RNF115	ENSG00000265491	-3.0440322810431	[]	[]	-4	hSpCas9	negative selection	3553524
145823817	145823840	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCCGCTGTAGCCGCCCACCGG	RNF115	ENSG00000265491	5.55376925091208	[]	[]	8	hSpCas9	negative selection	3553525
145771710	145771733	1	-	26780180	A375	viability (Avana lentiGuide)	ACAGATCTCCAGCTATTGAAGGG	RNF115	ENSG00000265491	-0.33315746783482	[]	[]	0	hSpCas9	negative selection	3662179
145823802	145823825	1	+	26780180	A375	viability (Avana lentiGuide)	AAAGTGGCAGAAAAACCGGTGGG	RNF115	ENSG00000265491	13.6421660605236	[]	[]	7	hSpCas9	negative selection	3662180
145771779	145771802	1	-	26780180	A375	viability (Avana lentiGuide)	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	12.8170654777361	[]	[]	7	hSpCas9	negative selection	3662181
145771852	145771875	1	+	26780180	A375	viability (Avana lentiGuide)	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	-0.953863576947991	[]	[]	-1	hSpCas9	negative selection	3662182
145823762	145823785	1	+	26780180	A375	viability (Avana lentiGuide)	GCGCTCTTACCGGTAGTTTGGGG	RNF115	ENSG00000265491	17.7910602776164	[]	[]	8	hSpCas9	negative selection	3662183
145823817	145823840	1	-	26780180	A375	viability (Avana lentiGuide)	GCGCCGCTGTAGCCGCCCACCGG	RNF115	ENSG00000265491	2.08830127777984	[]	[]	2	hSpCas9	negative selection	3662184
145771710	145771733	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGATCTCCAGCTATTGAAGGG	RNF115	ENSG00000265491	-0.5049549036515808	[6]	[5,3]	-6	hSpCas9	positive selection	3770786
145823802	145823825	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAAGTGGCAGAAAAACCGGTGGG	RNF115	ENSG00000265491	-1.552946494330822	[4]	[1,0]	-9	hSpCas9	positive selection	3770787
145771779	145771802	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	0.03416863444210452	[4]	[4,3]	0	hSpCas9	positive selection	3770788
145771852	145771875	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	-0.4276976168955871	[5]	[3,3]	-6	hSpCas9	positive selection	3770789
145823762	145823785	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCTCTTACCGGTAGTTTGGGG	RNF115	ENSG00000265491	-0.07674629831543926	[5]	[5,4]	-1	hSpCas9	positive selection	3770790
145823817	145823840	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCCGCTGTAGCCGCCCACCGG	RNF115	ENSG00000265491	0.45012870098151614	[4]	[5,5]	9	hSpCas9	positive selection	3770791
145771710	145771733	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGATCTCCAGCTATTGAAGGG	RNF115	ENSG00000265491	-0.17305483103500358	[5]	[3,5]	-2	hSpCas9	positive selection	3879393
145823802	145823825	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAAGTGGCAGAAAAACCGGTGGG	RNF115	ENSG00000265491	-1.7327748670488168	[4]	[0,0]	-9	hSpCas9	positive selection	3879394
145771779	145771802	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-1.069119810221291	[4]	[0,2]	-8	hSpCas9	positive selection	3879395
145771852	145771875	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	-0.6239164876811234	[3]	[2,1]	-7	hSpCas9	positive selection	3879396
145823762	145823785	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCTCTTACCGGTAGTTTGGGG	RNF115	ENSG00000265491	-0.23941071356137733	[6]	[3,5]	-3	hSpCas9	positive selection	3879397
145823817	145823840	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCCGCTGTAGCCGCCCACCGG	RNF115	ENSG00000265491	-0.10482233495561599	[5]	[3,4]	-1	hSpCas9	positive selection	3879398
145788931	145788954	1	+	26780180	A375	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.544707760889503	[]	[]	1	hSpCas9	negative selection	3989510
145750455	145750478	1	-	26780180	A375	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	1.11186806306122	[]	[]	5	hSpCas9	negative selection	3989511
145788938	145788961	1	-	26780180	A375	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.667989920826971	[]	[]	2	hSpCas9	negative selection	3989512
145771850	145771873	1	-	26780180	A375	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	1.55834342544715	[]	[]	8	hSpCas9	negative selection	3989513
145771753	145771776	1	+	26780180	A375	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.912395653835927	[]	[]	4	hSpCas9	negative selection	3989514
145750416	145750439	1	-	26780180	A375	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	1.68137244422134	[]	[]	9	hSpCas9	negative selection	3989515
145788931	145788954	1	+	26780180	HT29	viability (GeCKOv2 library)	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	1.12536359165306	[]	[]	5	hSpCas9	negative selection	4097476
145750455	145750478	1	-	26780180	HT29	viability (GeCKOv2 library)	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.633936557525579	[]	[]	2	hSpCas9	negative selection	4097477
145788938	145788961	1	-	26780180	HT29	viability (GeCKOv2 library)	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	1.0967353028151	[]	[]	5	hSpCas9	negative selection	4097478
145771850	145771873	1	-	26780180	HT29	viability (GeCKOv2 library)	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.834659320782203	[]	[]	3	hSpCas9	negative selection	4097479
145771753	145771776	1	+	26780180	HT29	viability (GeCKOv2 library)	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	1.71661668434282	[]	[]	8	hSpCas9	negative selection	4097480
145750416	145750439	1	-	26780180	HT29	viability (GeCKOv2 library)	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	1.58271851289403	[]	[]	8	hSpCas9	negative selection	4097481
145788907	145788930	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGAAGTGACAGATGATTCCAGG	RNF115	ENSG00000265491	-0.0006306107741727851	[4]	[2,3]	0	hSpCas9	positive selection	4166700
145788931	145788954	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.191573693940833	[3]	[0,2]	-4	hSpCas9	positive selection	4166701
145788938	145788961	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.20456448240592912	[3]	[2,3]	5	hSpCas9	positive selection	4166702
145750445	145750468	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGATCTTTTCCTTGTCAGCTGG	RNF115	ENSG00000265491	0.340982985403028	[3]	[1,4]	7	hSpCas9	positive selection	4166703
145750416	145750439	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.22221975163035193	[4]	[2,4]	5	hSpCas9	positive selection	4166704
145750485	145750508	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTGTAGCTTTTAGGACAACTGG	RNF115	ENSG00000265491	-0.1261932978750521	[3]	[1,1]	-3	hSpCas9	positive selection	4166705
145788907	145788930	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGAAGTGACAGATGATTCCAGG	RNF115	ENSG00000265491	0.24181878201737575	[4]	[3,3,3,0]	2	hSpCas9	positive selection	4230722
145788931	145788954	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.7913519376283662	[4]	[0,1,0,0]	-9	hSpCas9	positive selection	4230723
145788938	145788961	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.2092380337382038	[4]	[3,4,1,0]	1	hSpCas9	positive selection	4230724
145750445	145750468	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGATCTTTTCCTTGTCAGCTGG	RNF115	ENSG00000265491	1.1174164766102885	[3]	[4,4,2,3]	8	hSpCas9	positive selection	4230725
145750416	145750439	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.2364064660506583	[4]	[2,2,0,0]	-3	hSpCas9	positive selection	4230726
145750485	145750508	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTGTAGCTTTTAGGACAACTGG	RNF115	ENSG00000265491	0.9962263069034194	[3]	[3,0,2,3]	7	hSpCas9	positive selection	4230727
145771753	145771776	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.4113068716780708	[3]	[2,0]	-7	hSpCas9	positive selection	4295112
145788938	145788961	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.179424484599223	[1]	[1,1]	3	hSpCas9	positive selection	4295113
145771850	145771873	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.13392284628637147	[3]	[2,1]	-3	hSpCas9	positive selection	4295114
145788931	145788954	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.17407878002784366	[2]	[2,2]	3	hSpCas9	positive selection	4359366
145750416	145750439	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.1378945562540052	[3]	[3,1]	-3	hSpCas9	positive selection	4359367
145750455	145750478	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	-0.01431312664545717	[2]	[3,1]	0	hSpCas9	positive selection	4359368
145788932	145788954	1	+	27760321	OCIAML3	viability	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.11683019861676036	[204,159]	[108,211]	1	hSpCas9	negative selection	4435013
145771890	145771912	1	+	27760321	OCIAML3	viability	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	1.2493434739543645	[145,104]	[243,213]	9	hSpCas9	negative selection	4435014
145771850	145771872	1	-	27760321	OCIAML3	viability	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.041783541340083885	[343,327]	[206,318]	0	hSpCas9	negative selection	4435015
145771763	145771785	1	+	27760321	OCIAML3	viability	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	0.04973154479283742	[616,513]	[533,353]	0	hSpCas9	negative selection	4435016
145771703	145771725	1	+	27760321	OCIAML3	viability	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	-0.3588472362118661	[472,361]	[266,233]	-4	hSpCas9	negative selection	4435017
145788932	145788954	1	+	27760321	OCIAML2	viability	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.7198902957594373	[204,159]	[209,282]	8	hSpCas9	negative selection	4518476
145771890	145771912	1	+	27760321	OCIAML2	viability	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	0.45404220143245344	[145,104]	[81,210]	6	hSpCas9	negative selection	4518477
145771850	145771872	1	-	27760321	OCIAML2	viability	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.12468011849939448	[343,327]	[218,289]	-2	hSpCas9	negative selection	4518478
145771763	145771785	1	+	27760321	OCIAML2	viability	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	0.012966926188138161	[616,513]	[466,449]	0	hSpCas9	negative selection	4518479
145771703	145771725	1	+	27760321	OCIAML2	viability	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	0.09879268264690173	[472,361]	[307,425]	1	hSpCas9	negative selection	4518480
145788932	145788954	1	+	27760321	MV411	viability	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.37766207151781583	[204,159]	[154,155]	2	hSpCas9	negative selection	4601939
145771890	145771912	1	+	27760321	MV411	viability	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	0.7573613807447972	[145,104]	[110,179]	5	hSpCas9	negative selection	4601940
145771850	145771872	1	-	27760321	MV411	viability	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.31777786475754355	[343,327]	[432,41]	2	hSpCas9	negative selection	4601941
145771763	145771785	1	+	27760321	MV411	viability	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	0.9248016175053382	[616,513]	[551,935]	6	hSpCas9	negative selection	4601942
145771703	145771725	1	+	27760321	MV411	viability	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	0.7674557983034964	[472,361]	[478,444]	5	hSpCas9	negative selection	4601943
145788932	145788954	1	+	27760321	HL60	viability	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.9356553282488057	[204,159]	[173,398]	8	hSpCas9	negative selection	4685402
145771890	145771912	1	+	27760321	HL60	viability	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	0.3554552769875239	[145,104]	[173,82]	4	hSpCas9	negative selection	4685403
145771850	145771872	1	-	27760321	HL60	viability	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.0779202434879096	[343,327]	[292,286]	1	hSpCas9	negative selection	4685404
145771763	145771785	1	+	27760321	HL60	viability	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	0.4739116281700179	[616,513]	[684,589]	6	hSpCas9	negative selection	4685405
145771703	145771725	1	+	27760321	HL60	viability	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	0.04715756255163072	[472,361]	[355,342]	0	hSpCas9	negative selection	4685406
145788932	145788954	1	+	27760321	HT1080	viability	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-1.731960500091815	[159,124]	[18,14]	-6	hSpCas9	negative selection	4768865
145771890	145771912	1	+	27760321	HT1080	viability	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	0.8765853097209564	[104,81]	[44,93]	5	hSpCas9	negative selection	4768866
145771850	145771872	1	-	27760321	HT1080	viability	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.27641956563153747	[327,255]	[117,71]	-1	hSpCas9	negative selection	4768867
145771763	145771785	1	+	27760321	HT1080	viability	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	1.5863839285388859	[513,400]	[447,655]	8	hSpCas9	negative selection	4768868
145771703	145771725	1	+	27760321	HT1080	viability	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	0.8113958837083517	[361,282]	[319,121]	4	hSpCas9	negative selection	4768869
145788932	145788954	1	+	27760321	HT29	viability after 7 days	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.23893079738401712	[159,124]	[209,191,73]	-3	hSpCas9	negative selection	4852328
145771890	145771912	1	+	27760321	HT29	viability after 7 days	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	0.31940230766013755	[104,81]	[252,140,72]	5	hSpCas9	negative selection	4852329
145771850	145771872	1	-	27760321	HT29	viability after 7 days	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.2975633684401259	[327,255]	[258,493,160]	-4	hSpCas9	negative selection	4852330
145771763	145771785	1	+	27760321	HT29	viability after 7 days	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	0.6162262089353572	[513,400]	[792,958,934]	8	hSpCas9	negative selection	4852331
145771703	145771725	1	+	27760321	HT29	viability after 7 days	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	0.3711734192631165	[361,282]	[616,504,498]	5	hSpCas9	negative selection	4852332
145788932	145788954	1	+	27760321	HT29	viability after 25 days	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.11208715578764794	[159,124]	[109,279,137]	1	hSpCas9	negative selection	4935791
145771890	145771912	1	+	27760321	HT29	viability after 25 days	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	0.6229326192552593	[104,81]	[148,261,73]	7	hSpCas9	negative selection	4935792
145771850	145771872	1	-	27760321	HT29	viability after 25 days	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.36253406817195366	[327,255]	[194,278,313]	-4	hSpCas9	negative selection	4935793
145771763	145771785	1	+	27760321	HT29	viability after 25 days	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	0.4594197543122987	[513,400]	[647,689,833]	5	hSpCas9	negative selection	4935794
145771703	145771725	1	+	27760321	HT29	viability after 25 days	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	0.5410470579849083	[361,282]	[648,510,429]	6	hSpCas9	negative selection	4935795
145788932	145788954	1	+	27760321	HT29	viability after 22 days	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.30501755509447337	[159,124]	[119,189,89]	-3	hSpCas9	negative selection	5019254
145771890	145771912	1	+	27760321	HT29	viability after 22 days	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	1.630776483367648	[104,81]	[504,329,162]	9	hSpCas9	negative selection	5019255
145771850	145771872	1	-	27760321	HT29	viability after 22 days	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.7013989296335473	[327,255]	[208,178,234]	-5	hSpCas9	negative selection	5019256
145771763	145771785	1	+	27760321	HT29	viability after 22 days	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	0.3501787378105659	[513,400]	[662,663,695]	4	hSpCas9	negative selection	5019257
145771703	145771725	1	+	27760321	HT29	viability after 22 days	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	0.33676229679577563	[361,282]	[531,514,362]	3	hSpCas9	negative selection	5019258
145788932	145788954	1	+	27760321	HT29	viability after 19 days	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.06827274566982511	[159,124]	[166,239,63]	0	hSpCas9	negative selection	5102717
145771890	145771912	1	+	27760321	HT29	viability after 19 days	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	0.31479651804859343	[104,81]	[189,110,104]	3	hSpCas9	negative selection	5102718
145771850	145771872	1	-	27760321	HT29	viability after 19 days	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-1.0802247617041725	[327,255]	[180,186,109]	-6	hSpCas9	negative selection	5102719
145771763	145771785	1	+	27760321	HT29	viability after 19 days	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	0.8045105059488173	[513,400]	[958,1097,696]	8	hSpCas9	negative selection	5102720
145771703	145771725	1	+	27760321	HT29	viability after 19 days	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	0.4288620195243244	[361,282]	[626,646,238]	4	hSpCas9	negative selection	5102721
145788932	145788954	1	+	27760321	HT29	viability after 16 days	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.24243809993872834	[159,124]	[128,163,109]	-3	hSpCas9	negative selection	5186180
145771890	145771912	1	+	27760321	HT29	viability after 16 days	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	1.3717655046380353	[104,81]	[273,363,171]	9	hSpCas9	negative selection	5186181
145771850	145771872	1	-	27760321	HT29	viability after 16 days	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.03073999210701045	[327,255]	[299,261,396]	0	hSpCas9	negative selection	5186182
145771763	145771785	1	+	27760321	HT29	viability after 16 days	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	0.8305989756879257	[513,400]	[647,1173,876]	8	hSpCas9	negative selection	5186183
145771703	145771725	1	+	27760321	HT29	viability after 16 days	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	0.942546594379372	[361,282]	[743,740,598]	9	hSpCas9	negative selection	5186184
145788932	145788954	1	+	27760321	HT29	viability after 13 days	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.04906406175140354	[159,124]	[144,235,101]	0	hSpCas9	negative selection	5269643
145771890	145771912	1	+	27760321	HT29	viability after 13 days	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	0.7673685654673366	[104,81]	[306,153,97]	8	hSpCas9	negative selection	5269644
145771850	145771872	1	-	27760321	HT29	viability after 13 days	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.704230054008559	[327,255]	[237,217,169]	-6	hSpCas9	negative selection	5269645
145771763	145771785	1	+	27760321	HT29	viability after 13 days	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	0.4642927875368254	[513,400]	[877,701,622]	6	hSpCas9	negative selection	5269646
145771703	145771725	1	+	27760321	HT29	viability after 13 days	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	-0.08679916749862712	[361,282]	[243,423,386]	-1	hSpCas9	negative selection	5269647
145788932	145788954	1	+	27760321	HT29	viability after 10 days	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.46001139373492017	[159,124]	[285,241,206]	6	hSpCas9	negative selection	5353106
145771890	145771912	1	+	27760321	HT29	viability after 10 days	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	0.019303146121121273	[104,81]	[166,137,51]	0	hSpCas9	negative selection	5353107
145771850	145771872	1	-	27760321	HT29	viability after 10 days	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.30874452886075465	[327,255]	[289,376,219]	-4	hSpCas9	negative selection	5353108
145771763	145771785	1	+	27760321	HT29	viability after 10 days	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	0.6105151492476741	[513,400]	[1030,676,901]	8	hSpCas9	negative selection	5353109
145771703	145771725	1	+	27760321	HT29	viability after 10 days	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	0.26358116163762685	[361,282]	[591,430,426]	3	hSpCas9	negative selection	5353110
145788932	145788954	1	+	27760321	MOLM13	viability	ATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.39186970017061806	[204,159]	[77,181]	2	hSpCas9	negative selection	5436569
145771890	145771912	1	+	27760321	MOLM13	viability	AAACATCGTGTGATCCAAATGG	RNF115	ENSG00000265491	1.276558807375888	[145,104]	[37,281]	8	hSpCas9	negative selection	5436570
145771850	145771872	1	-	27760321	MOLM13	viability	TTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.6846318505933544	[343,327]	[444,185]	5	hSpCas9	negative selection	5436571
145771763	145771785	1	+	27760321	MOLM13	viability	TCCGACCCAATGGCAACCGTGG	RNF115	ENSG00000265491	-1.4313774012289961	[616,513]	[180,63]	-7	hSpCas9	negative selection	5436572
145771703	145771725	1	+	27760321	MOLM13	viability	CAACTCACCCTTCAATAGCTGG	RNF115	ENSG00000265491	0.032223108047799744	[472,361]	[325,164]	0	hSpCas9	negative selection	5436573
145823982	145824005	1	-	27661255	K562	viability	GACCGACGCGGGCTCTGAAGCGG	RNF115	ENSG00000265491	0.23401976359148702	[520,497]	[545,421]	7	dCas9-KRAB	negative selection	5507766
145823978	145824001	1	-	27661255	K562	viability	GACGCGGGCTCTGAAGCGGTGGG	RNF115	ENSG00000265491	0.7690648873946646	[113,238]	[220,250]	9	dCas9-KRAB	negative selection	5507767
145823961	145823984	1	-	27661255	K562	viability	GGTGGGCCGCACCGAGGCGGCGG	RNF115	ENSG00000265491	0.11701838759244976	[1028,1260]	[1139,858]	4	dCas9-KRAB	negative selection	5507768
145823912	145823935	1	-	27661255	K562	viability	GTAGCGGCCTGGCGAGGGACGGG	RNF115	ENSG00000265491	0.19335973043611565	[1025,791]	[940,742]	6	dCas9-KRAB	negative selection	5507769
145823870	145823893	1	-	27661255	K562	viability	GCCGCGGCGGAGGGCAAAAATGG	RNF115	ENSG00000265491	0.5934332060076816	[211,333]	[354,301]	9	dCas9-KRAB	negative selection	5507770
145823867	145823890	1	-	27661255	K562	viability	GCGGCGGAGGGCAAAAATGGCGG	RNF115	ENSG00000265491	0.00960929113541198	[469,541]	[488,334]	0	dCas9-KRAB	negative selection	5507771
145824014	145824037	1	+	27661255	K562	viability	GGCCAGGCCCAGAAACGCGGCGG	RNF115	ENSG00000265491	-0.13607177619167599	[409,399]	[327,265]	-5	dCas9-KRAB	negative selection	5507772
145771753	145771776	1	+	27260156	BXPC3	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.18325855460491575	[461]	[395,437,453,411]	-4	hSpCas9	negative selection	5567572
145788938	145788961	1	-	27260156	BXPC3	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.29437208613282295	[149]	[222,234,155,140]	6	hSpCas9	negative selection	5567573
145771850	145771873	1	-	27260156	BXPC3	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.22702321613386434	[612]	[708,707,711,889]	5	hSpCas9	negative selection	5567574
145788931	145788954	1	+	27260156	BXPC3	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.06928018106176004	[429]	[444,420,469,564]	1	hSpCas9	negative selection	5631826
145750416	145750439	1	-	27260156	BXPC3	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.15970220627200205	[837]	[660,819,788,885]	-4	hSpCas9	negative selection	5631827
145750455	145750478	1	-	27260156	BXPC3	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.037916455405184735	[394]	[399,425,452,415]	0	hSpCas9	negative selection	5631828
145771753	145771776	1	+	27260156	A673	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.12933542703693302	[461]	[574,464,485,510]	-3	hSpCas9	negative selection	5688823
145788938	145788961	1	-	27260156	A673	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.2807885042873066	[149]	[287,201,212,177]	6	hSpCas9	negative selection	5688824
145771850	145771873	1	-	27260156	A673	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.14352093710184355	[612]	[918,666,765,920]	3	hSpCas9	negative selection	5688825
145788931	145788954	1	+	27260156	A673	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.041076647249505494	[429]	[608,526,429,569]	1	hSpCas9	negative selection	5753077
145750416	145750439	1	-	27260156	A673	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.062192507411222175	[837]	[1121,995,849,899]	-1	hSpCas9	negative selection	5753078
145750455	145750478	1	-	27260156	A673	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.11145547622265367	[394]	[675,470,444,474]	2	hSpCas9	negative selection	5753079
145771753	145771776	1	+	27260156	A375	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.6401811051249177	[461]	[320,486,322,279]	-7	hSpCas9	negative selection	5810074
145788938	145788961	1	-	27260156	A375	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.44496508670194634	[149]	[286,212,184,261]	6	hSpCas9	negative selection	5810075
145771850	145771873	1	-	27260156	A375	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.14801851185221532	[612]	[603,702,592,684]	-2	hSpCas9	negative selection	5810076
145788931	145788954	1	+	27260156	A375	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.20025715218216023	[429]	[675,707,559,401]	3	hSpCas9	negative selection	5874328
145750416	145750439	1	-	27260156	A375	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.17956537631808656	[837]	[1256,1087,1122,975]	2	hSpCas9	negative selection	5874329
145750455	145750478	1	-	27260156	A375	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	-0.2125381277082632	[394]	[363,446,391,394]	-3	hSpCas9	negative selection	5874330
145771753	145771776	1	+	27260156	COLO741	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.3120317372770731	[461]	[718,747,728]	6	hSpCas9	negative selection	5931325
145788938	145788961	1	-	27260156	COLO741	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.27438461036214457	[149]	[213,199,275]	6	hSpCas9	negative selection	5931326
145771850	145771873	1	-	27260156	COLO741	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.15336939368493252	[612]	[866,761,973]	3	hSpCas9	negative selection	5931327
145788931	145788954	1	+	27260156	COLO741	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.32152624281030007	[429]	[480,450,392]	-6	hSpCas9	negative selection	5995579
145750416	145750439	1	-	27260156	COLO741	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.1640120333822167	[837]	[1103,1038,749]	-4	hSpCas9	negative selection	5995580
145750455	145750478	1	-	27260156	COLO741	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.22464730601574082	[394]	[453,494,791]	5	hSpCas9	negative selection	5995581
145771753	145771776	1	+	27260156	CAL120	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.026121832785951996	[461]	[620,514,565]	0	hSpCas9	negative selection	6052576
145788938	145788961	1	-	27260156	CAL120	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	-0.19111436369907886	[149]	[111,224,145]	-3	hSpCas9	negative selection	6052577
145771850	145771873	1	-	27260156	CAL120	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.24988772747257956	[612]	[579,471,858]	-4	hSpCas9	negative selection	6052578
145788931	145788954	1	+	27260156	CAL120	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.08331666954803438	[429]	[758,550,421]	1	hSpCas9	negative selection	6116830
145750416	145750439	1	-	27260156	CAL120	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.11865266261608931	[837]	[921,1036,916]	-2	hSpCas9	negative selection	6116831
145750455	145750478	1	-	27260156	CAL120	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.3062486135348818	[394]	[616,573,632]	4	hSpCas9	negative selection	6116832
145771753	145771776	1	+	27260156	CADOES1	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.017930436358963853	[461]	[475,328,344,551]	0	hSpCas9	negative selection	6173827
145788938	145788961	1	-	27260156	CADOES1	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.5194152898825888	[149]	[311,129,168,187]	8	hSpCas9	negative selection	6173828
145771850	145771873	1	-	27260156	CADOES1	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.4627240192513635	[612]	[681,844,759,858]	7	hSpCas9	negative selection	6173829
145788931	145788954	1	+	27260156	CADOES1	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.05369869479963771	[429]	[397,292,413,437]	-1	hSpCas9	negative selection	6238081
145750416	145750439	1	-	27260156	CADOES1	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.1230173018002827	[837]	[782,708,592,779]	-2	hSpCas9	negative selection	6238082
145750455	145750478	1	-	27260156	CADOES1	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.24280007825945052	[394]	[338,552,318,531]	4	hSpCas9	negative selection	6238083
145771753	145771776	1	+	27260156	EWS502	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.04068825492842393	[461]	[564,475,432,410]	0	hSpCas9	negative selection	6295078
145788938	145788961	1	-	27260156	EWS502	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.41625228809406867	[149]	[260,143,327,104]	7	hSpCas9	negative selection	6295079
145771850	145771873	1	-	27260156	EWS502	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.5342309337445985	[612]	[862,1141,919,824]	8	hSpCas9	negative selection	6295080
145788931	145788954	1	+	27260156	EWS502	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.03576914331774694	[429]	[448,426,402,499]	0	hSpCas9	negative selection	6359332
145750416	145750439	1	-	27260156	EWS502	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.04345538790709991	[837]	[1108,881,1069,547]	0	hSpCas9	negative selection	6359333
145750455	145750478	1	-	27260156	EWS502	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.2218382599207105	[394]	[323,521,416,720]	4	hSpCas9	negative selection	6359334
145771753	145771776	1	+	27260156	EW8	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.2909764213596451	[461]	[524,364,300,672]	5	hSpCas9	negative selection	6416329
145788938	145788961	1	-	27260156	EW8	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.10390671718003852	[149]	[103,72,134,205]	2	hSpCas9	negative selection	6416330
145771850	145771873	1	-	27260156	EW8	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.2952758774045555	[612]	[694,641,552,565]	5	hSpCas9	negative selection	6416331
145788931	145788954	1	+	27260156	EW8	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.09145535205805744	[429]	[363,453,227,282]	-2	hSpCas9	negative selection	6480583
145750416	145750439	1	-	27260156	EW8	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.34628505847747454	[837]	[579,494,474,599]	-6	hSpCas9	negative selection	6480584
145750455	145750478	1	-	27260156	EW8	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.019337624253252084	[394]	[404,394,230,290]	0	hSpCas9	negative selection	6480585
145771753	145771776	1	+	27260156	CORL105	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.17966217473792767	[461]	[461,485,519,447]	-3	hSpCas9	negative selection	6537580
145788938	145788961	1	-	27260156	CORL105	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	-0.022872961821335913	[149]	[217,137,187,151]	0	hSpCas9	negative selection	6537581
145771850	145771873	1	-	27260156	CORL105	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.07782819279471342	[612]	[809,714,775,733]	1	hSpCas9	negative selection	6537582
145788931	145788954	1	+	27260156	CORL105	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.1435304065496135	[429]	[404,412,502,507]	-3	hSpCas9	negative selection	6601834
145750416	145750439	1	-	27260156	CORL105	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.18649844079835642	[837]	[994,1319,1144,1001]	3	hSpCas9	negative selection	6601835
145750455	145750478	1	-	27260156	CORL105	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.16047310537563425	[394]	[454,547,533,529]	3	hSpCas9	negative selection	6601836
145771753	145771776	1	+	27260156	HS294T	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.37092640966139884	[461]	[152,82,145,176]	-5	hSpCas9	negative selection	6658831
145788938	145788961	1	-	27260156	HS294T	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	-0.06951922880574157	[149]	[40,37,47,103]	-1	hSpCas9	negative selection	6658832
145771850	145771873	1	-	27260156	HS294T	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.6922710496413429	[612]	[280,389,337,560]	8	hSpCas9	negative selection	6658833
145788931	145788954	1	+	27260156	HS294T	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.02699585141173913	[429]	[160,148,143,205]	0	hSpCas9	negative selection	6723085
145750416	145750439	1	-	27260156	HS294T	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.1420011413620509	[837]	[330,262,291,586]	2	hSpCas9	negative selection	6723086
145750455	145750478	1	-	27260156	HS294T	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.5286906907363188	[394]	[112,214,198,392]	7	hSpCas9	negative selection	6723087
145771753	145771776	1	+	27260156	HCC44	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.6951544606892328	[461]	[354,222,373,360]	-7	hSpCas9	negative selection	6780082
145788938	145788961	1	-	27260156	HCC44	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.7494398715523036	[149]	[616,158,169,222]	9	hSpCas9	negative selection	6780083
145771850	145771873	1	-	27260156	HCC44	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.2529930430549719	[612]	[537,631,767,410]	-4	hSpCas9	negative selection	6780084
145788931	145788954	1	+	27260156	HCC44	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.1896195398313653	[429]	[804,462,433,527]	3	hSpCas9	negative selection	6844336
145750416	145750439	1	-	27260156	HCC44	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.09634223907081474	[837]	[901,942,1006,706]	-1	hSpCas9	negative selection	6844337
145750455	145750478	1	-	27260156	HCC44	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	-0.4808022203799323	[394]	[406,271,477,167]	-6	hSpCas9	negative selection	6844338
145771753	145771776	1	+	27260156	G402	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.07159590257515716	[461]	[530,543,673,605]	0	hSpCas9	negative selection	6901333
145788938	145788961	1	-	27260156	G402	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.21731046414248456	[149]	[103,239,105,377]	2	hSpCas9	negative selection	6901334
145771850	145771873	1	-	27260156	G402	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.22696276379526878	[612]	[786,538,742,506]	-3	hSpCas9	negative selection	6901335
145788931	145788954	1	+	27260156	G402	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.17002542256798203	[429]	[827,488,831,254]	2	hSpCas9	negative selection	6965587
145750416	145750439	1	-	27260156	G402	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.01324341530482298	[837]	[959,947,1601,618]	0	hSpCas9	negative selection	6965588
145750455	145750478	1	-	27260156	G402	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.5022336623347416	[394]	[975,423,706,649]	6	hSpCas9	negative selection	6965589
145771753	145771776	1	+	27260156	L33	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.4298781382855407	[461]	[520,345,310,630]	8	hSpCas9	negative selection	7022584
145788938	145788961	1	-	27260156	L33	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.023379909024762835	[149]	[96,64,85,217]	0	hSpCas9	negative selection	7022585
145771850	145771873	1	-	27260156	L33	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.4612051325525427	[612]	[762,347,635,754]	8	hSpCas9	negative selection	7022586
145788931	145788954	1	+	27260156	L33	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.07989780474023736	[429]	[397,145,289,411]	-2	hSpCas9	negative selection	7086838
145750416	145750439	1	-	27260156	L33	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.21544823692326642	[837]	[701,282,474,738]	-5	hSpCas9	negative selection	7086839
145750455	145750478	1	-	27260156	L33	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.2744510147592124	[394]	[431,180,340,495]	6	hSpCas9	negative selection	7086840
145771753	145771776	1	+	27260156	K562	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.12851850064172848	[461]	[275,469,612,421]	1	hSpCas9	negative selection	7143835
145788938	145788961	1	-	27260156	K562	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.1958049781185578	[149]	[170,191,202,57]	2	hSpCas9	negative selection	7143836
145771850	145771873	1	-	27260156	K562	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.4599808509763734	[612]	[653,1196,738,450]	6	hSpCas9	negative selection	7143837
145788931	145788954	1	+	27260156	K562	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.38082800559722396	[429]	[324,814,454,403]	5	hSpCas9	negative selection	7208089
145750416	145750439	1	-	27260156	K562	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.37049485215826905	[837]	[1081,868,947,948]	5	hSpCas9	negative selection	7208090
145750455	145750478	1	-	27260156	K562	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.249670654413376	[394]	[435,504,412,327]	3	hSpCas9	negative selection	7208091
145771753	145771776	1	+	27260156	HT29	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.06548236175879518	[461]	[622,587,736,421]	1	hSpCas9	negative selection	7265086
145788938	145788961	1	-	27260156	HT29	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.3361104404069275	[149]	[337,251,205,143]	6	hSpCas9	negative selection	7265087
145771850	145771873	1	-	27260156	HT29	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.2149031869554	[612]	[782,943,882,845]	4	hSpCas9	negative selection	7265088
145788931	145788954	1	+	27260156	HT29	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.12919427924067003	[429]	[623,653,527,496]	2	hSpCas9	negative selection	7329340
145750416	145750439	1	-	27260156	HT29	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.13506822628069226	[837]	[856,1082,828,940]	-3	hSpCas9	negative selection	7329341
145750455	145750478	1	-	27260156	HT29	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	-0.11552680677047256	[394]	[499,542,425,327]	-2	hSpCas9	negative selection	7329342
145771753	145771776	1	+	27260156	MHHES1	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.12406428723093206	[461]	[606,548,345,429]	-2	hSpCas9	negative selection	7386337
145788938	145788961	1	-	27260156	MHHES1	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.29136832800565804	[149]	[308,236,155,148]	5	hSpCas9	negative selection	7386338
145771850	145771873	1	-	27260156	MHHES1	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.28925087184951626	[612]	[867,1035,759,737]	5	hSpCas9	negative selection	7386339
145788931	145788954	1	+	27260156	MHHES1	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.05966553854966264	[429]	[494,611,453,335]	-1	hSpCas9	negative selection	7450591
145750416	145750439	1	-	27260156	MHHES1	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.03524892739726371	[837]	[1050,933,1196,728]	0	hSpCas9	negative selection	7450592
145750455	145750478	1	-	27260156	MHHES1	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.20970925367240673	[394]	[515,534,583,432]	4	hSpCas9	negative selection	7450593
145771753	145771776	1	+	27260156	MEWO	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.012994792767755945	[461]	[368,500,424]	0	hSpCas9	negative selection	7507588
145788938	145788961	1	-	27260156	MEWO	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.2613819235368937	[149]	[186,214,105]	5	hSpCas9	negative selection	7507589
145771850	145771873	1	-	27260156	MEWO	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.13239072088514814	[612]	[656,671,561]	3	hSpCas9	negative selection	7507590
145788931	145788954	1	+	27260156	MEWO	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.0997175714259522	[429]	[394,371,362]	-2	hSpCas9	negative selection	7571842
145750416	145750439	1	-	27260156	MEWO	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.10057647911190426	[837]	[954,692,588]	-2	hSpCas9	negative selection	7571843
145750455	145750478	1	-	27260156	MEWO	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.26924942925719303	[394]	[625,446,297]	6	hSpCas9	negative selection	7571844
145771753	145771776	1	+	27260156	LNCAPCLONEFGC	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.3159425649251897	[461]	[278,334,438,307]	-5	hSpCas9	negative selection	7628839
145788938	145788961	1	-	27260156	LNCAPCLONEFGC	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	-0.15568115552353445	[149]	[116,107,95,163]	-2	hSpCas9	negative selection	7628840
145771850	145771873	1	-	27260156	LNCAPCLONEFGC	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.027455257391471255	[612]	[593,484,477,614]	0	hSpCas9	negative selection	7628841
145788931	145788954	1	+	27260156	LNCAPCLONEFGC	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.12697759977071502	[429]	[251,295,574,341]	-2	hSpCas9	negative selection	7693093
145750416	145750439	1	-	27260156	LNCAPCLONEFGC	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.3281687209564178	[837]	[535,616,612,653]	-5	hSpCas9	negative selection	7693094
145750455	145750478	1	-	27260156	LNCAPCLONEFGC	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.012988384797823022	[394]	[284,383,300,464]	0	hSpCas9	negative selection	7693095
145771753	145771776	1	+	27260156	PANC0327	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.8604621578494424	[461]	[237,134,329,213]	-8	hSpCas9	negative selection	7750090
145788938	145788961	1	-	27260156	PANC0327	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	-0.15820457908931052	[149]	[96,78,149,154]	-2	hSpCas9	negative selection	7750091
145771850	145771873	1	-	27260156	PANC0327	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.19706526909185762	[612]	[534,618,605,729]	3	hSpCas9	negative selection	7750092
145788931	145788954	1	+	27260156	PANC0327	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.6446038986859179	[429]	[210,187,351,230]	-7	hSpCas9	negative selection	7814344
145750416	145750439	1	-	27260156	PANC0327	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.613298228283153	[837]	[685,420,397,465]	-7	hSpCas9	negative selection	7814345
145750455	145750478	1	-	27260156	PANC0327	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	-0.19192220649135167	[394]	[350,220,184,485]	-3	hSpCas9	negative selection	7814346
145771753	145771776	1	+	27260156	NCIH2009	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.08250176837504358	[461]	[522,811,471]	-1	hSpCas9	negative selection	7871341
145788938	145788961	1	-	27260156	NCIH2009	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.08837468046105679	[149]	[238,181,250]	1	hSpCas9	negative selection	7871342
145771850	145771873	1	-	27260156	NCIH2009	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.11036438801854231	[612]	[901,792,1074]	1	hSpCas9	negative selection	7871343
145788931	145788954	1	+	27260156	NCIH2009	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.19171308611336738	[429]	[659,693,697]	2	hSpCas9	negative selection	7935595
145750416	145750439	1	-	27260156	NCIH2009	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.10337516439518901	[837]	[1088,844,1337]	-1	hSpCas9	negative selection	7935596
145750455	145750478	1	-	27260156	NCIH2009	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	-0.18680431309045115	[394]	[575,525,368]	-3	hSpCas9	negative selection	7935597
145771753	145771776	1	+	27260156	NCIH1373	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-1.2844007045985282	[461]	[219,130,114,106]	-8	hSpCas9	negative selection	7992592
145788938	145788961	1	-	27260156	NCIH1373	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	1.092771065947538	[149]	[64,487,119,190]	9	hSpCas9	negative selection	7992593
145771850	145771873	1	-	27260156	NCIH1373	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.015171113570475292	[612]	[709,597,860,159]	0	hSpCas9	negative selection	7992594
145788931	145788954	1	+	27260156	NCIH1373	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.495343186723773	[429]	[1253,752,444,85]	5	hSpCas9	negative selection	8056846
145750416	145750439	1	-	27260156	NCIH1373	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.8969962933441351	[837]	[843,375,470,100]	-7	hSpCas9	negative selection	8056847
145750455	145750478	1	-	27260156	NCIH1373	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	-0.2930388220353716	[394]	[704,212,295,77]	-3	hSpCas9	negative selection	8056848
145771753	145771776	1	+	27260156	PATU8902	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.7055717793419475	[461]	[364,477,266,512]	-6	hSpCas9	negative selection	8113843
145788938	145788961	1	-	27260156	PATU8902	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.7631505235795765	[149]	[538,265,272,355]	7	hSpCas9	negative selection	8113844
145771850	145771873	1	-	27260156	PATU8902	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.6380523138410904	[612]	[901,542,315,475]	-6	hSpCas9	negative selection	8113845
145788931	145788954	1	+	27260156	PATU8902	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.22833745857758206	[429]	[633,406,409,627]	-2	hSpCas9	negative selection	8178097
145750416	145750439	1	-	27260156	PATU8902	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.29823316378377274	[837]	[645,717,654,1971]	-3	hSpCas9	negative selection	8178098
145750455	145750478	1	-	27260156	PATU8902	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	-0.8022343258869362	[394]	[346,229,325,357]	-6	hSpCas9	negative selection	8178099
145771753	145771776	1	+	27260156	PANC1	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.03433408037206379	[461]	[345,346,425,412]	0	hSpCas9	negative selection	8235094
145788938	145788961	1	-	27260156	PANC1	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.45138162117545866	[149]	[167,263,121,166]	7	hSpCas9	negative selection	8235095
145771850	145771873	1	-	27260156	PANC1	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.18116148584616742	[612]	[679,608,593,509]	3	hSpCas9	negative selection	8235096
145788931	145788954	1	+	27260156	PANC1	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.14990436668880225	[429]	[381,505,366,398]	2	hSpCas9	negative selection	8299348
145750416	145750439	1	-	27260156	PANC1	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.0665932885731515	[837]	[808,871,707,652]	1	hSpCas9	negative selection	8299349
145750455	145750478	1	-	27260156	PANC1	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.03415409617815565	[394]	[413,150,432,344]	0	hSpCas9	negative selection	8299350
145771753	145771776	1	+	27260156	PANC0813	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.030549041653499257	[461]	[593,473,542,605]	0	hSpCas9	negative selection	8356345
145788938	145788961	1	-	27260156	PANC0813	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.0418480330312434	[149]	[277,119,204,133]	0	hSpCas9	negative selection	8356346
145771850	145771873	1	-	27260156	PANC0813	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.008389550898251164	[612]	[744,760,648,709]	0	hSpCas9	negative selection	8356347
145788931	145788954	1	+	27260156	PANC0813	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.056384072069238025	[429]	[526,418,684,472]	0	hSpCas9	negative selection	8420599
145750416	145750439	1	-	27260156	PANC0813	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.23686217324607106	[837]	[870,868,650,944]	-4	hSpCas9	negative selection	8420600
145750455	145750478	1	-	27260156	PANC0813	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	-0.42142554875021737	[394]	[351,365,327,339]	-6	hSpCas9	negative selection	8420601
145771753	145771776	1	+	27260156	RDES	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.2225358113502337	[461]	[291,451,515,610]	-4	hSpCas9	negative selection	8477596
145788938	145788961	1	-	27260156	RDES	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.32389780270492063	[149]	[202,198,214,248]	5	hSpCas9	negative selection	8477597
145771850	145771873	1	-	27260156	RDES	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.05582659020410102	[612]	[570,859,725,780]	0	hSpCas9	negative selection	8477598
145788931	145788954	1	+	27260156	RDES	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.21358562484495805	[429]	[325,432,482,482]	-4	hSpCas9	negative selection	8541850
145750416	145750439	1	-	27260156	RDES	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.2460082668771172	[837]	[519,883,905,1007]	-4	hSpCas9	negative selection	8541851
145750455	145750478	1	-	27260156	RDES	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.15123339062929103	[394]	[384,513,521,625]	2	hSpCas9	negative selection	8541852
145771753	145771776	1	+	27260156	PC3	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.14865565435098757	[461]	[323,426,952,548]	3	hSpCas9	negative selection	8598847
145788938	145788961	1	-	27260156	PC3	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.4692706243001701	[149]	[187,113,442,158]	8	hSpCas9	negative selection	8598848
145771850	145771873	1	-	27260156	PC3	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.16017239823386842	[612]	[488,650,1271,554]	3	hSpCas9	negative selection	8598849
145788931	145788954	1	+	27260156	PC3	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.057029912439264974	[429]	[236,321,956,532]	1	hSpCas9	negative selection	8663101
145750416	145750439	1	-	27260156	PC3	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.24100788712061716	[837]	[379,615,1021,1034]	-5	hSpCas9	negative selection	8663102
145750455	145750478	1	-	27260156	PC3	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.018265542570009785	[394]	[243,460,534,434]	0	hSpCas9	negative selection	8663103
145771753	145771776	1	+	27260156	PATU8988T	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.18871373846635864	[461]	[384,550,748,336]	3	hSpCas9	negative selection	8720098
145788938	145788961	1	-	27260156	PATU8988T	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.294419226959171	[149]	[212,204,92,205]	5	hSpCas9	negative selection	8720099
145771850	145771873	1	-	27260156	PATU8988T	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.4402289373712083	[612]	[723,697,813,982]	7	hSpCas9	negative selection	8720100
145788931	145788954	1	+	27260156	PATU8988T	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.0928245536279016	[429]	[272,492,311,499]	-2	hSpCas9	negative selection	8784352
145750416	145750439	1	-	27260156	PATU8988T	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.251427629243861	[837]	[538,734,679,779]	-4	hSpCas9	negative selection	8784353
145750455	145750478	1	-	27260156	PATU8988T	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.19919622187982255	[394]	[259,491,545,459]	3	hSpCas9	negative selection	8784354
145771753	145771776	1	+	27260156	T47D	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.20596410971107976	[461]	[463,355,506,550]	-4	hSpCas9	negative selection	8841349
145788938	145788961	1	-	27260156	T47D	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.26924489190398515	[149]	[151,210,290,185]	6	hSpCas9	negative selection	8841350
145771850	145771873	1	-	27260156	T47D	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.1255016311340701	[612]	[805,678,807,832]	2	hSpCas9	negative selection	8841351
145788931	145788954	1	+	27260156	T47D	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.06897683836335242	[429]	[553,453,498,603]	1	hSpCas9	negative selection	8905603
145750416	145750439	1	-	27260156	T47D	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.2199576459993381	[837]	[879,853,845,768]	-5	hSpCas9	negative selection	8905604
145750455	145750478	1	-	27260156	T47D	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.07588777504932276	[394]	[506,466,474,492]	1	hSpCas9	negative selection	8905605
145771753	145771776	1	+	27260156	SU8686	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.13350249573525347	[461]	[370,416,417,475]	-2	hSpCas9	negative selection	8962600
145788938	145788961	1	-	27260156	SU8686	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.7782269348767982	[149]	[208,228,237,368]	9	hSpCas9	negative selection	8962601
145771850	145771873	1	-	27260156	SU8686	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.5557552983600799	[612]	[870,670,1008,1080]	8	hSpCas9	negative selection	8962602
145788931	145788954	1	+	27260156	SU8686	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.14932369190461828	[429]	[478,378,520,530]	2	hSpCas9	negative selection	9026854
145750416	145750439	1	-	27260156	SU8686	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	0.19215600968258928	[837]	[808,715,875,1526]	3	hSpCas9	negative selection	9026855
145750455	145750478	1	-	27260156	SU8686	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.18675879682055696	[394]	[470,427,375,512]	3	hSpCas9	negative selection	9026856
145771753	145771776	1	+	27260156	SKES1	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.3281176488839845	[461]	[615,660,524,527]	7	hSpCas9	negative selection	9083851
145788938	145788961	1	-	27260156	SKES1	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	-0.40442814874132416	[149]	[162,136,51,109]	-7	hSpCas9	negative selection	9083852
145771850	145771873	1	-	27260156	SKES1	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.23725936812009973	[612]	[822,803,762,531]	5	hSpCas9	negative selection	9083853
145788931	145788954	1	+	27260156	SKES1	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	0.20908338965074716	[429]	[454,514,544,462]	4	hSpCas9	negative selection	9148105
145750416	145750439	1	-	27260156	SKES1	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.08787706125156403	[837]	[903,866,648,749]	-2	hSpCas9	negative selection	9148106
145750455	145750478	1	-	27260156	SKES1	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.20679227021994256	[394]	[412,634,445,348]	4	hSpCas9	negative selection	9148107
145771753	145771776	1	+	27260156	TOV112D	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.1827758005792059	[461]	[246,592,521,302]	-4	hSpCas9	negative selection	9205102
145788938	145788961	1	-	27260156	TOV112D	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.4498910718716802	[149]	[148,256,198,222]	8	hSpCas9	negative selection	9205103
145771850	145771873	1	-	27260156	TOV112D	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	-0.007209057448234357	[612]	[569,933,489,526]	0	hSpCas9	negative selection	9205104
145788931	145788954	1	+	27260156	TOV112D	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.39820659797428204	[429]	[319,336,231,416]	-7	hSpCas9	negative selection	9269356
145750416	145750439	1	-	27260156	TOV112D	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.13827964295134476	[837]	[829,724,672,815]	-3	hSpCas9	negative selection	9269357
145750455	145750478	1	-	27260156	TOV112D	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.241776759482781	[394]	[510,524,452,400]	4	hSpCas9	negative selection	9269358
145771753	145771776	1	+	27260156	TC71	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	0.15999766111567787	[461]	[588,453,528,646]	4	hSpCas9	negative selection	9326353
145788938	145788961	1	-	27260156	TC71	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.1854620171172372	[149]	[196,188,169,174]	4	hSpCas9	negative selection	9326354
145771850	145771873	1	-	27260156	TC71	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.4067775384616963	[612]	[901,900,758,928]	8	hSpCas9	negative selection	9326355
145788931	145788954	1	+	27260156	TC71	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.05635454658393618	[429]	[479,412,430,448]	-1	hSpCas9	negative selection	9390607
145750416	145750439	1	-	27260156	TC71	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.2321980581694293	[837]	[705,870,696,789]	-6	hSpCas9	negative selection	9390608
145750455	145750478	1	-	27260156	TC71	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	0.0017219110283681616	[394]	[524,350,397,419]	0	hSpCas9	negative selection	9390609
145771753	145771776	1	+	27260156	TC32	viability	GATCTGTATCTCCGACCCAATGG	RNF115	ENSG00000265491	-0.2434399919459047	[461]	[381,318,462,308]	-4	hSpCas9	negative selection	9447604
145788938	145788961	1	-	27260156	TC32	viability	ATATGTCCCAGATGTGAATCAGG	RNF115	ENSG00000265491	0.4861343194273835	[149]	[175,240,197,143]	8	hSpCas9	negative selection	9447605
145771850	145771873	1	-	27260156	TC32	viability	CTTTCTAAGTAGCAGTCCACTGG	RNF115	ENSG00000265491	0.09532732152545498	[612]	[431,577,883,613]	1	hSpCas9	negative selection	9447606
145788931	145788954	1	+	27260156	TC32	viability	AATAAAGCCTGATTCACATCTGG	RNF115	ENSG00000265491	-0.41577210195022707	[429]	[322,191,398,337]	-7	hSpCas9	negative selection	9511858
145750416	145750439	1	-	27260156	TC32	viability	TCCAACAGTGACAGTAACTCAGG	RNF115	ENSG00000265491	-0.149116412232986	[837]	[693,602,831,731]	-3	hSpCas9	negative selection	9511859
145750455	145750478	1	-	27260156	TC32	viability	AGGCCCTCCCCCAGCTGACAAGG	RNF115	ENSG00000265491	-0.03759870557388273	[394]	[323,219,578,401]	0	hSpCas9	negative selection	9511860
145771851	145771874	1	+	27869803	HPAFII	viability after 27 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.555397896883014	[396]	[255,348,NaN]	4	hSpCas9	negative selection	9528604
145771834	145771857	1	+	27869803	HPAFII	viability after 27 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	3.4339331204004937	[1]	[0,19,NaN]	9	hSpCas9	negative selection	9528605
145751505	145751528	1	-	27869803	HPAFII	viability after 27 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.7505679274546433	[342]	[86,123,NaN]	-5	hSpCas9	negative selection	9528606
145751504	145751527	1	-	27869803	HPAFII	viability after 27 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	1.0425883500475548	[171]	[104,253,NaN]	8	hSpCas9	negative selection	9528607
145747994	145748017	1	-	27869803	HPAFII	viability after 27 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.4594165433752435	[289]	[207,210,NaN]	4	hSpCas9	negative selection	9528608
145746875	145746898	1	-	27869803	HPAFII	viability after 27 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	0.15738882213754568	[377]	[75,342,NaN]	1	hSpCas9	negative selection	9528609
145771851	145771874	1	+	27869803	HPAFII	viability after 15 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.4019716259530921	[396]	[683,488,NaN]	4	hSpCas9	negative selection	9611053
145771834	145771857	1	+	27869803	HPAFII	viability after 15 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	2.4608821341206655	[1]	[17,7,NaN]	9	hSpCas9	negative selection	9611054
145751505	145751528	1	-	27869803	HPAFII	viability after 15 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.5441843800791814	[342]	[430,141,NaN]	-5	hSpCas9	negative selection	9611055
145751504	145751527	1	-	27869803	HPAFII	viability after 15 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	0.25787111125277024	[171]	[204,230,NaN]	3	hSpCas9	negative selection	9611056
145747994	145748017	1	-	27869803	HPAFII	viability after 15 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.22442236263234158	[289]	[492,283,NaN]	2	hSpCas9	negative selection	9611057
145746875	145746898	1	-	27869803	HPAFII	viability after 15 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	-0.5734315570946855	[377]	[153,346,NaN]	-6	hSpCas9	negative selection	9611058
145771851	145771874	1	+	27869803	ASPC1	viability after 36 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.49843178694716317	[1051]	[555,450,540]	5	hSpCas9	negative selection	9693502
145771834	145771857	1	+	27869803	ASPC1	viability after 36 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	-0.46892400989316707	[324]	[148,105,14]	-5	hSpCas9	negative selection	9693503
145751505	145751528	1	-	27869803	ASPC1	viability after 36 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.4734530853051173	[810]	[233,210,174]	-5	hSpCas9	negative selection	9693504
145751504	145751527	1	-	27869803	ASPC1	viability after 36 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	0.005822848236832212	[372]	[181,134,89]	0	hSpCas9	negative selection	9693505
145747994	145748017	1	-	27869803	ASPC1	viability after 36 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.7022727863412103	[645]	[322,663,157]	7	hSpCas9	negative selection	9693506
145746875	145746898	1	-	27869803	ASPC1	viability after 36 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	0.3629757113316277	[783]	[726,69,308]	3	hSpCas9	negative selection	9693507
145771851	145771874	1	+	27869803	PATU8988S	viability after 35 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.6501406484186425	[876]	[467,640,NaN]	7	hSpCas9	negative selection	9775951
145771834	145771857	1	+	27869803	PATU8988S	viability after 35 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	1.3237065008507714	[235]	[200,274,NaN]	9	hSpCas9	negative selection	9775952
145751505	145751528	1	-	27869803	PATU8988S	viability after 35 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.30072699459429914	[727]	[252,222,NaN]	-3	hSpCas9	negative selection	9775953
145751504	145751527	1	-	27869803	PATU8988S	viability after 35 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	0.9168671956583507	[365]	[411,143,NaN]	8	hSpCas9	negative selection	9775954
145747994	145748017	1	-	27869803	PATU8988S	viability after 35 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	-0.10497370528954894	[600]	[253,195,NaN]	-1	hSpCas9	negative selection	9775955
145746875	145746898	1	-	27869803	PATU8988S	viability after 35 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	0.23491645582443604	[691]	[322,332,NaN]	2	hSpCas9	negative selection	9775956
145771851	145771874	1	+	27869803	PATU8988S	viability after 31 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.3178657878887263	[876]	[306,599,NaN]	4	hSpCas9	negative selection	9858400
145771834	145771857	1	+	27869803	PATU8988S	viability after 31 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	0.9626133216535108	[235]	[145,230,NaN]	9	hSpCas9	negative selection	9858401
145751505	145751528	1	-	27869803	PATU8988S	viability after 31 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.6005967291066021	[727]	[179,205,NaN]	-6	hSpCas9	negative selection	9858402
145751504	145751527	1	-	27869803	PATU8988S	viability after 31 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	1.0693093519528794	[365]	[329,275,NaN]	9	hSpCas9	negative selection	9858403
145747994	145748017	1	-	27869803	PATU8988S	viability after 31 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	-0.05423756650111132	[600]	[243,213,NaN]	0	hSpCas9	negative selection	9858404
145746875	145746898	1	-	27869803	PATU8988S	viability after 31 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	0.3470170519736459	[691]	[368,327,NaN]	4	hSpCas9	negative selection	9858405
145771851	145771874	1	+	27869803	HPAFII	viability after 35 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.6864243821355269	[396]	[250,404,NaN]	4	hSpCas9	negative selection	9940849
145771834	145771857	1	+	27869803	HPAFII	viability after 35 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	2.7141989875385333	[1]	[0,12,NaN]	9	hSpCas9	negative selection	9940850
145751505	145751528	1	-	27869803	HPAFII	viability after 35 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.31138579090143736	[342]	[122,158,NaN]	-2	hSpCas9	negative selection	9940851
145751504	145751527	1	-	27869803	HPAFII	viability after 35 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	1.1988529100067808	[171]	[86,326,NaN]	7	hSpCas9	negative selection	9940852
145747994	145748017	1	-	27869803	HPAFII	viability after 35 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.2847204085719176	[289]	[96,270,NaN]	1	hSpCas9	negative selection	9940853
145746875	145746898	1	-	27869803	HPAFII	viability after 35 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	0.15701663666147558	[377]	[115,322,NaN]	1	hSpCas9	negative selection	9940854
145771851	145771874	1	+	27869803	HPAFII	viability after 31 days	CAGTGGACTGCTACTTAGAAAGG	RNF115	ENSG00000265491	0.8045850298876609	[396]	[280,506,NaN]	6	hSpCas9	negative selection	10023298
145771834	145771857	1	+	27869803	HPAFII	viability after 31 days	GCTCTATTATCTTGGTCCAGTGG	RNF115	ENSG00000265491	3.2354696432466037	[1]	[0,20,NaN]	9	hSpCas9	negative selection	10023299
145751505	145751528	1	-	27869803	HPAFII	viability after 31 days	TCTCATCTCACGTATAGGAGCGG	RNF115	ENSG00000265491	-0.6777724950056936	[342]	[138,99,NaN]	-4	hSpCas9	negative selection	10023300
145751504	145751527	1	-	27869803	HPAFII	viability after 31 days	CTCATCTCACGTATAGGAGCGGG	RNF115	ENSG00000265491	0.5715106028544616	[171]	[52,241,NaN]	4	hSpCas9	negative selection	10023301
145747994	145748017	1	-	27869803	HPAFII	viability after 31 days	TATTGTGCCGTGGCTAGAACTGG	RNF115	ENSG00000265491	0.2595764537558749	[289]	[112,283,NaN]	1	hSpCas9	negative selection	10023302
145746875	145746898	1	-	27869803	HPAFII	viability after 31 days	ACAGTCAGCTACATGACCGATGG	RNF115	ENSG00000265491	0.06619435811380348	[377]	[67,389,NaN]	0	hSpCas9	negative selection	10023303
145747987	145748010	1	+	28162770	P31FUJ	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	-0.09307744074776525	[58]	[64]	-1	hSpCas9	negative selection	10226021
145751470	145751493	1	-	28162770	P31FUJ	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	-0.06774295814388243	[65]	[73]	0	hSpCas9	negative selection	10226022
145823814	145823837	1	+	28162770	P31FUJ	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	-0.5698371916919491	[167]	[132]	-5	hSpCas9	negative selection	10226023
145751482	145751505	1	-	28162770	P31FUJ	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	0.14570941883935107	[119]	[155]	1	hSpCas9	negative selection	10226024
145771852	145771875	1	+	28162770	P31FUJ	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	-0.22706583486523407	[250]	[251]	-2	hSpCas9	negative selection	10226025
145771747	145771770	1	-	28162770	P31FUJ	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	-0.16079095949899053	[253]	[266]	-1	hSpCas9	negative selection	10226026
145752986	145753009	1	+	28162770	P31FUJ	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	-0.1533677369199735	[264]	[279]	-1	hSpCas9	negative selection	10226027
145750406	145750429	1	-	28162770	P31FUJ	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	0.03147109805277387	[193]	[232]	0	hSpCas9	negative selection	10226028
145748004	145748027	1	-	28162770	P31FUJ	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	0.1297678749703296	[321]	[413]	1	hSpCas9	negative selection	10226029
145771779	145771802	1	-	28162770	P31FUJ	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.1285912094262447	[800]	[860]	-1	hSpCas9	negative selection	10226030
145747987	145748010	1	+	28162770	TF1	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10395387
145751470	145751493	1	-	28162770	TF1	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10395388
145823814	145823837	1	+	28162770	TF1	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10395389
145751482	145751505	1	-	28162770	TF1	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10395390
145771852	145771875	1	+	28162770	TF1	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	NaN	[NaN]	[107]	1	hSpCas9	negative selection	10395391
145771747	145771770	1	-	28162770	TF1	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	NaN	[NaN]	[236]	1	hSpCas9	negative selection	10395392
145752986	145753009	1	+	28162770	TF1	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	NaN	[NaN]	[342]	1	hSpCas9	negative selection	10395393
145750406	145750429	1	-	28162770	TF1	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	NaN	[NaN]	[33]	1	hSpCas9	negative selection	10395394
145748004	145748027	1	-	28162770	TF1	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	NaN	[NaN]	[358]	1	hSpCas9	negative selection	10395395
145771779	145771802	1	-	28162770	TF1	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	NaN	[NaN]	[825]	1	hSpCas9	negative selection	10395396
145747987	145748010	1	+	28162770	SKM1	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	-0.9740047914670557	[29]	[26]	-6	hSpCas9	negative selection	10564753
145751470	145751493	1	-	28162770	SKM1	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	0.5136013337624336	[20]	[52]	5	hSpCas9	negative selection	10564754
145823814	145823837	1	+	28162770	SKM1	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	-0.718908205057902	[53]	[57]	-5	hSpCas9	negative selection	10564755
145751482	145751505	1	-	28162770	SKM1	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	-0.40017503308052266	[52]	[70]	-3	hSpCas9	negative selection	10564756
145771852	145771875	1	+	28162770	SKM1	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	0.20936247288732968	[90]	[185]	2	hSpCas9	negative selection	10564757
145771747	145771770	1	-	28162770	SKM1	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	-1.0100740461745774	[89]	[78]	-6	hSpCas9	negative selection	10564758
145752986	145753009	1	+	28162770	SKM1	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	-0.10071772608806906	[73]	[121]	-1	hSpCas9	negative selection	10564759
145750406	145750429	1	-	28162770	SKM1	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	-0.34666368847534734	[40]	[56]	-3	hSpCas9	negative selection	10564760
145748004	145748027	1	-	28162770	SKM1	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	0.24212863939771018	[65]	[137]	2	hSpCas9	negative selection	10564761
145771779	145771802	1	-	28162770	SKM1	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.21194821633801886	[132]	[202]	-2	hSpCas9	negative selection	10564762
145747987	145748010	1	+	28162770	SKM1	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	-0.9740047914670557	[29]	[26]	-6	hSpCas9	negative selection	10734119
145751470	145751493	1	-	28162770	SKM1	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	0.5136013337624336	[20]	[52]	5	hSpCas9	negative selection	10734120
145823814	145823837	1	+	28162770	SKM1	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	-0.718908205057902	[53]	[57]	-5	hSpCas9	negative selection	10734121
145751482	145751505	1	-	28162770	SKM1	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	-0.40017503308052266	[52]	[70]	-3	hSpCas9	negative selection	10734122
145771852	145771875	1	+	28162770	SKM1	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	0.20936247288732968	[90]	[185]	2	hSpCas9	negative selection	10734123
145771747	145771770	1	-	28162770	SKM1	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	-1.0100740461745774	[89]	[78]	-6	hSpCas9	negative selection	10734124
145752986	145753009	1	+	28162770	SKM1	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	-0.10071772608806906	[73]	[121]	-1	hSpCas9	negative selection	10734125
145750406	145750429	1	-	28162770	SKM1	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	-0.34666368847534734	[40]	[56]	-3	hSpCas9	negative selection	10734126
145748004	145748027	1	-	28162770	SKM1	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	0.24212863939771018	[65]	[137]	2	hSpCas9	negative selection	10734127
145771779	145771802	1	-	28162770	SKM1	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.21194821633801886	[132]	[202]	-2	hSpCas9	negative selection	10734128
145747987	145748010	1	+	28162770	PL21	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	-2.6200393479258675	[112]	[7]	-9	hSpCas9	negative selection	10903485
145751470	145751493	1	-	28162770	PL21	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	-1.9697853869529927	[35]	[3]	-8	hSpCas9	negative selection	10903486
145823814	145823837	1	+	28162770	PL21	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	-2.283676162774936	[178]	[15]	-8	hSpCas9	negative selection	10903487
145751482	145751505	1	-	28162770	PL21	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	2.14603220914987	[162]	[313]	9	hSpCas9	negative selection	10903488
145771852	145771875	1	+	28162770	PL21	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	-0.010220251352231043	[198]	[85]	0	hSpCas9	negative selection	10903489
145771747	145771770	1	-	28162770	PL21	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	0.8938083746529764	[229]	[185]	7	hSpCas9	negative selection	10903490
145752986	145753009	1	+	28162770	PL21	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	0.9386473734639319	[186]	[155]	7	hSpCas9	negative selection	10903491
145750406	145750429	1	-	28162770	PL21	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	0.6293909729878648	[100]	[67]	5	hSpCas9	negative selection	10903492
145748004	145748027	1	-	28162770	PL21	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	-1.0014942466803305	[206]	[44]	-6	hSpCas9	negative selection	10903493
145771779	145771802	1	-	28162770	PL21	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.4501143464835555	[564]	[179]	-3	hSpCas9	negative selection	10903494
145747987	145748010	1	+	28162770	P31FUJ	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	-0.09307744074776525	[58]	[64]	-1	hSpCas9	negative selection	11072851
145751470	145751493	1	-	28162770	P31FUJ	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	-0.06774295814388243	[65]	[73]	0	hSpCas9	negative selection	11072852
145823814	145823837	1	+	28162770	P31FUJ	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	-0.5698371916919491	[167]	[132]	-5	hSpCas9	negative selection	11072853
145751482	145751505	1	-	28162770	P31FUJ	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	0.14570941883935107	[119]	[155]	1	hSpCas9	negative selection	11072854
145771852	145771875	1	+	28162770	P31FUJ	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	-0.22706583486523407	[250]	[251]	-2	hSpCas9	negative selection	11072855
145771747	145771770	1	-	28162770	P31FUJ	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	-0.16079095949899053	[253]	[266]	-1	hSpCas9	negative selection	11072856
145752986	145753009	1	+	28162770	P31FUJ	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	-0.1533677369199735	[264]	[279]	-1	hSpCas9	negative selection	11072857
145750406	145750429	1	-	28162770	P31FUJ	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	0.03147109805277387	[193]	[232]	0	hSpCas9	negative selection	11072858
145748004	145748027	1	-	28162770	P31FUJ	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	0.1297678749703296	[321]	[413]	1	hSpCas9	negative selection	11072859
145771779	145771802	1	-	28162770	P31FUJ	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.1285912094262447	[800]	[860]	-1	hSpCas9	negative selection	11072860
145747987	145748010	1	+	28162770	OCIAML5	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	-0.6594214929216013	[27]	[31]	-4	hSpCas9	negative selection	11242217
145751470	145751493	1	-	28162770	OCIAML5	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	-0.48949649147928864	[69]	[89]	-3	hSpCas9	negative selection	11242218
145823814	145823837	1	+	28162770	OCIAML5	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	0.359437534329715	[75]	[175]	3	hSpCas9	negative selection	11242219
145751482	145751505	1	-	28162770	OCIAML5	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	0.21919211230582492	[78]	[165]	1	hSpCas9	negative selection	11242220
145771852	145771875	1	+	28162770	OCIAML5	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	0.303211654613914	[219]	[489]	2	hSpCas9	negative selection	11242221
145771747	145771770	1	-	28162770	OCIAML5	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	0.8237110930428261	[117]	[376]	7	hSpCas9	negative selection	11242222
145752986	145753009	1	+	28162770	OCIAML5	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	0.13115771638517626	[172]	[341]	1	hSpCas9	negative selection	11242223
145750406	145750429	1	-	28162770	OCIAML5	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	-1.3182429191346419	[133]	[96]	-6	hSpCas9	negative selection	11242224
145748004	145748027	1	-	28162770	OCIAML5	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	-0.39263495222669964	[199]	[274]	-3	hSpCas9	negative selection	11242225
145771779	145771802	1	-	28162770	OCIAML5	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.48422680424895104	[333]	[430]	-3	hSpCas9	negative selection	11242226
145747987	145748010	1	+	28162770	EOL1	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	0.8921262938781571	[134]	[131]	7	hSpCas9	negative selection	11411583
145751470	145751493	1	-	28162770	EOL1	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	1.1469401929069822	[77]	[90]	8	hSpCas9	negative selection	11411584
145823814	145823837	1	+	28162770	EOL1	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	-0.5054400691742809	[290]	[107]	-4	hSpCas9	negative selection	11411585
145751482	145751505	1	-	28162770	EOL1	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	0.4591668866020509	[242]	[175]	4	hSpCas9	negative selection	11411586
145771852	145771875	1	+	28162770	EOL1	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	0.12504071133561556	[549]	[315]	1	hSpCas9	negative selection	11411587
145771747	145771770	1	-	28162770	EOL1	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	-0.06976111635160975	[505]	[253]	0	hSpCas9	negative selection	11411588
145752986	145753009	1	+	28162770	EOL1	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	-0.12436182891041186	[239]	[115]	-1	hSpCas9	negative selection	11411589
145750406	145750429	1	-	28162770	EOL1	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	0.9968986157952187	[174]	[183]	8	hSpCas9	negative selection	11411590
145748004	145748027	1	-	28162770	EOL1	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	0.5559031777761421	[305]	[236]	5	hSpCas9	negative selection	11411591
145771779	145771802	1	-	28162770	EOL1	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	0.05605255469902626	[722]	[395]	0	hSpCas9	negative selection	11411592
145747987	145748010	1	+	28162770	MOLM13	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	-1.6510516911789286	[138]	[31]	-7	hSpCas9	negative selection	11580949
145751470	145751493	1	-	28162770	MOLM13	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	-0.27835402620963823	[103]	[61]	-2	hSpCas9	negative selection	11580950
145823814	145823837	1	+	28162770	MOLM13	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	-0.34284026729368183	[213]	[121]	-2	hSpCas9	negative selection	11580951
145751482	145751505	1	-	28162770	MOLM13	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	0.440010348969142	[208]	[204]	3	hSpCas9	negative selection	11580952
145771852	145771875	1	+	28162770	MOLM13	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	0.570069776351057	[435]	[467]	4	hSpCas9	negative selection	11580953
145771747	145771770	1	-	28162770	MOLM13	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	1.7225844864656432	[346]	[827]	9	hSpCas9	negative selection	11580954
145752986	145753009	1	+	28162770	MOLM13	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	-0.2921598257346687	[314]	[185]	-2	hSpCas9	negative selection	11580955
145750406	145750429	1	-	28162770	MOLM13	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	-1.6168910386524407	[402]	[94]	-7	hSpCas9	negative selection	11580956
145748004	145748027	1	-	28162770	MOLM13	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	0.27008259848640415	[319]	[278]	2	hSpCas9	negative selection	11580957
145771779	145771802	1	-	28162770	MOLM13	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.6218515995541744	[712]	[334]	-4	hSpCas9	negative selection	11580958
145747987	145748010	1	+	28162770	HEL	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	0.2860453189523181	[104]	[81]	2	hSpCas9	negative selection	11750315
145751470	145751493	1	-	28162770	HEL	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	-2.218554897168051	[108]	[14]	-8	hSpCas9	negative selection	11750316
145823814	145823837	1	+	28162770	HEL	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	0.11637098519004896	[192]	[133]	0	hSpCas9	negative selection	11750317
145751482	145751505	1	-	28162770	HEL	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	0.27500704749986976	[199]	[154]	2	hSpCas9	negative selection	11750318
145771852	145771875	1	+	28162770	HEL	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	-0.3644209595725091	[403]	[200]	-3	hSpCas9	negative selection	11750319
145771747	145771770	1	-	28162770	HEL	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	1.2748816012112911	[370]	[574]	9	hSpCas9	negative selection	11750320
145752986	145753009	1	+	28162770	HEL	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	-0.6830313291813994	[187]	[74]	-4	hSpCas9	negative selection	11750321
145750406	145750429	1	-	28162770	HEL	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	-0.2893571034978396	[331]	[173]	-2	hSpCas9	negative selection	11750322
145748004	145748027	1	-	28162770	HEL	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	0.4249853054674295	[206]	[177]	3	hSpCas9	negative selection	11750323
145771779	145771802	1	-	28162770	HEL	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.13486874666319504	[575]	[335]	-1	hSpCas9	negative selection	11750324
145747987	145748010	1	+	28162770	MV411	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	0.2980636238527432	[55]	[57]	2	hSpCas9	negative selection	11919681
145751470	145751493	1	-	28162770	MV411	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	0.32687201827718004	[52]	[55]	3	hSpCas9	negative selection	11919682
145823814	145823837	1	+	28162770	MV411	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	-0.3175149892068866	[178]	[120]	-2	hSpCas9	negative selection	11919683
145751482	145751505	1	-	28162770	MV411	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	0.6113209621115162	[121]	[156]	5	hSpCas9	negative selection	11919684
145771852	145771875	1	+	28162770	MV411	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	0.15000339987714884	[244]	[228]	1	hSpCas9	negative selection	11919685
145771747	145771770	1	-	28162770	MV411	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	-0.5574321078852342	[289]	[165]	-4	hSpCas9	negative selection	11919686
145752986	145753009	1	+	28162770	MV411	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	0.9002154357315031	[186]	[293]	7	hSpCas9	negative selection	11919687
145750406	145750429	1	-	28162770	MV411	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	-0.63779226197115	[156]	[84]	-4	hSpCas9	negative selection	11919688
145748004	145748027	1	-	28162770	MV411	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	0.5469978326416832	[194]	[239]	5	hSpCas9	negative selection	11919689
145771779	145771802	1	-	28162770	MV411	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.27094947516186507	[486]	[339]	-2	hSpCas9	negative selection	11919690
145747987	145748010	1	+	28162770	MONOMAC1	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	-0.29433404841446853	[45]	[42]	-3	hSpCas9	negative selection	12089047
145751470	145751493	1	-	28162770	MONOMAC1	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	1.4550398495201395	[34]	[109]	9	hSpCas9	negative selection	12089048
145823814	145823837	1	+	28162770	MONOMAC1	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	-0.8011081707284146	[113]	[74]	-6	hSpCas9	negative selection	12089049
145751482	145751505	1	-	28162770	MONOMAC1	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	-0.1464107739895858	[83]	[86]	-1	hSpCas9	negative selection	12089050
145771852	145771875	1	+	28162770	MONOMAC1	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	-0.2890659855518993	[177]	[166]	-3	hSpCas9	negative selection	12089051
145771747	145771770	1	-	28162770	MONOMAC1	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	-0.879296549135625	[137]	[85]	-6	hSpCas9	negative selection	12089052
145752986	145753009	1	+	28162770	MONOMAC1	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	-0.11741967899618544	[140]	[148]	-1	hSpCas9	negative selection	12089053
145750406	145750429	1	-	28162770	MONOMAC1	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	-0.8636131133343619	[99]	[62]	-6	hSpCas9	negative selection	12089054
145748004	145748027	1	-	28162770	MONOMAC1	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	-0.5365233133312206	[123]	[97]	-4	hSpCas9	negative selection	12089055
145771779	145771802	1	-	28162770	MONOMAC1	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-1.0117712994827552	[342]	[194]	-7	hSpCas9	negative selection	12089056
145747987	145748010	1	+	28162770	OCIAML2	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	-0.47062982524216124	[15]	[63]	-4	hSpCas9	negative selection	12258413
145751470	145751493	1	-	28162770	OCIAML2	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	-0.6632749031845571	[15]	[55]	-5	hSpCas9	negative selection	12258414
145823814	145823837	1	+	28162770	OCIAML2	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	-1.1569693463383994	[34]	[86]	-6	hSpCas9	negative selection	12258415
145751482	145751505	1	-	28162770	OCIAML2	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	0.5532169167122066	[29]	[243]	5	hSpCas9	negative selection	12258416
145771852	145771875	1	+	28162770	OCIAML2	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	0.22980989289893095	[69]	[454]	2	hSpCas9	negative selection	12258417
145771747	145771770	1	-	28162770	OCIAML2	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	1.0795672573183186	[48]	[573]	8	hSpCas9	negative selection	12258418
145752986	145753009	1	+	28162770	OCIAML2	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	-0.18522760637991298	[47]	[233]	-1	hSpCas9	negative selection	12258419
145750406	145750429	1	-	28162770	OCIAML2	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	-0.8702372839513989	[30]	[93]	-6	hSpCas9	negative selection	12258420
145748004	145748027	1	-	28162770	OCIAML2	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	-0.1811232080471765	[44]	[219]	-1	hSpCas9	negative selection	12258421
145771779	145771802	1	-	28162770	OCIAML2	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	0.5857250245448742	[90]	[756]	6	hSpCas9	negative selection	12258422
145747987	145748010	1	+	28162770	OCIAML3	viability	GTACTCACCAGTTCTAGCCACGG	RNF115	ENSG00000265491	0.45910369613539936	[19]	[82]	4	hSpCas9	negative selection	12427779
145751470	145751493	1	-	28162770	OCIAML3	viability	CAACCCTGGGGACTATGCCTGGG	RNF115	ENSG00000265491	-0.14149543562665645	[18]	[51]	-1	hSpCas9	negative selection	12427780
145823814	145823837	1	+	28162770	OCIAML3	viability	AAACCGGTGGGCGGCTACAGCGG	RNF115	ENSG00000265491	1.6032938000494545	[28]	[265]	9	hSpCas9	negative selection	12427781
145751482	145751505	1	-	28162770	OCIAML3	viability	GATGCTGCACTCCAACCCTGGGG	RNF115	ENSG00000265491	0.23090565311774575	[34]	[123]	2	hSpCas9	negative selection	12427782
145771852	145771875	1	+	28162770	OCIAML3	viability	AGTGGACTGCTACTTAGAAAGGG	RNF115	ENSG00000265491	-0.07044568426715025	[87]	[252]	0	hSpCas9	negative selection	12427783
145771747	145771770	1	-	28162770	OCIAML3	viability	GGTCGGAGATACAGATCTCGAGG	RNF115	ENSG00000265491	-0.009045139603006958	[72]	[218]	0	hSpCas9	negative selection	12427784
145752986	145753009	1	+	28162770	OCIAML3	viability	AGGGTGTGGAGATCCAGGAATGG	RNF115	ENSG00000265491	0.097870064313505	[51]	[167]	0	hSpCas9	negative selection	12427785
145750406	145750429	1	-	28162770	OCIAML3	viability	ACAGTAACTCAGGAACAAGTTGG	RNF115	ENSG00000265491	0.6408973923258335	[40]	[192]	6	hSpCas9	negative selection	12427786
145748004	145748027	1	-	28162770	OCIAML3	viability	ACAGCAGTTGTATTGTGCCGTGG	RNF115	ENSG00000265491	-0.0009172587196066007	[58]	[177]	0	hSpCas9	negative selection	12427787
145771779	145771802	1	-	28162770	OCIAML3	viability	TCTGGGGAGCAAGACCTCCACGG	RNF115	ENSG00000265491	-0.6042759757779904	[140]	[279]	-4	hSpCas9	negative selection	12427788