Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 153830
• Symbol: RNF145
• Description: ring finger protein 145

DataSource: http://genomecrispr.dkfz.de/#!/results/RNF145

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
159161559	159161582	5	-	26472758	Jiyoye	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	-0.19466093777967886	[257]	[169]	-1	hSpCas9	negative selection	138004
159174098	159174121	5	+	26472758	Jiyoye	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	-0.09163047546556835	[64]	[45]	0	hSpCas9	negative selection	138005
159203593	159203616	5	-	26472758	Jiyoye	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	2.051031571280598	[7]	[24]	8	hSpCas9	negative selection	138006
159162920	159162943	5	+	26472758	Jiyoye	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	1.2510561795885915	[77]	[139]	7	hSpCas9	negative selection	138007
159161493	159161516	5	+	26472758	Jiyoye	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	0.4699111368538361	[44]	[46]	3	hSpCas9	negative selection	138008
159161352	159161375	5	-	26472758	Jiyoye	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-0.25908722131713097	[145]	[91]	-2	hSpCas9	negative selection	138009
159203569	159203592	5	-	26472758	Jiyoye	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	0.06279243579081539	[258]	[203]	0	hSpCas9	negative selection	138010
159203548	159203571	5	-	26472758	Jiyoye	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.9832840950523045	[96]	[36]	-6	hSpCas9	negative selection	138011
159174119	159174142	5	+	26472758	Jiyoye	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	3.5771003829481853	[0]	[8]	9	hSpCas9	negative selection	138012
159161472	159161495	5	+	26472758	Jiyoye	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	-0.06736312952163243	[131]	[94]	0	hSpCas9	negative selection	138013
159161559	159161582	5	-	26472758	KBM7	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	0.13656631040536704	[577,351]	[281,193]	1	hSpCas9	negative selection	329122
159174098	159174121	5	+	26472758	KBM7	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	0.4986480821296692	[303,232]	[198,156]	5	hSpCas9	negative selection	329123
159203593	159203616	5	-	26472758	KBM7	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	0.4778796803506362	[114,113]	[144,12]	5	hSpCas9	negative selection	329124
159162920	159162943	5	+	26472758	KBM7	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	0.3739634638604949	[673,465]	[445,249]	4	hSpCas9	negative selection	329125
159161493	159161516	5	+	26472758	KBM7	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	0.09144595676095713	[273,107]	[74,106]	0	hSpCas9	negative selection	329126
159161352	159161375	5	-	26472758	KBM7	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-0.1903119234997851	[981,500]	[326,269]	-2	hSpCas9	negative selection	329127
159203569	159203592	5	-	26472758	KBM7	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	0.7498858946246665	[1184,1002]	[1005,732]	7	hSpCas9	negative selection	329128
159203548	159203571	5	-	26472758	KBM7	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	0.8710487838292995	[275,225]	[191,234]	8	hSpCas9	negative selection	329129
159174119	159174142	5	+	26472758	KBM7	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	0.7766192246245824	[96,65]	[79,50]	8	hSpCas9	negative selection	329130
159161472	159161495	5	+	26472758	KBM7	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	1.0439374236757866	[579,574]	[640,491]	9	hSpCas9	negative selection	329131
159161559	159161582	5	-	26472758	Raji	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	0.329077145826494	[294]	[85]	3	hSpCas9	negative selection	520240
159174098	159174121	5	+	26472758	Raji	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	0.44687000164526636	[97]	[30]	4	hSpCas9	negative selection	520241
159203593	159203616	5	-	26472758	Raji	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	-0.10762935559725095	[64]	[13]	-1	hSpCas9	negative selection	520242
159162920	159162943	5	+	26472758	Raji	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	0.1803853663165062	[288]	[75]	1	hSpCas9	negative selection	520243
159161493	159161516	5	+	26472758	Raji	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	-0.3311894783660334	[102]	[18]	-3	hSpCas9	negative selection	520244
159161352	159161375	5	-	26472758	Raji	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-1.2276007123392092	[443]	[43]	-7	hSpCas9	negative selection	520245
159203569	159203592	5	-	26472758	Raji	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	0.05932739402909615	[640]	[154]	0	hSpCas9	negative selection	520246
159203548	159203571	5	-	26472758	Raji	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.5235913631043929	[222]	[35]	-4	hSpCas9	negative selection	520247
159174119	159174142	5	+	26472758	Raji	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	-1.0784830099377343	[90]	[9]	-7	hSpCas9	negative selection	520248
159161472	159161495	5	+	26472758	Raji	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	-0.4382660413227307	[361]	[61]	-4	hSpCas9	negative selection	520249
159161559	159161582	5	-	26472758	K562	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	0.7728429603321642	[424]	[612]	6	hSpCas9	negative selection	711358
159174098	159174121	5	+	26472758	K562	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	-0.0051951624050252665	[213]	[179]	0	hSpCas9	negative selection	711359
159203593	159203616	5	-	26472758	K562	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	-6.588471286498294	[113]	[0]	-9	hSpCas9	negative selection	711360
159162920	159162943	5	+	26472758	K562	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	-0.0035087857771386455	[645]	[543]	0	hSpCas9	negative selection	711361
159161493	159161516	5	+	26472758	K562	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	0.2718994640885539	[103]	[105]	2	hSpCas9	negative selection	711362
159161352	159161375	5	-	26472758	K562	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-0.1210629471381646	[495]	[384]	-1	hSpCas9	negative selection	711363
159203569	159203592	5	-	26472758	K562	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	-0.206194544173534	[998]	[730]	-1	hSpCas9	negative selection	711364
159203548	159203571	5	-	26472758	K562	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.5683027041409724	[201]	[114]	-4	hSpCas9	negative selection	711365
159174119	159174142	5	+	26472758	K562	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	2.147742708254773	[53]	[201]	9	hSpCas9	negative selection	711366
159161472	159161495	5	+	26472758	K562	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.46573169138359427	[572]	[667]	3	hSpCas9	negative selection	711367
159158741	159158764	5	-	26627737	DLD1	viability	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.7057873650281672	[1157]	[456,744,577]	7	hSpCas9	negative selection	827827
159161472	159161495	5	+	26627737	DLD1	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.38096750651539324	[2508]	[1265,988,835]	4	hSpCas9	negative selection	827828
159203531	159203554	5	-	26627737	DLD1	viability	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	-0.38452449893298546	[867]	[187,254,185]	-4	hSpCas9	negative selection	827829
159209889	159209912	5	-	26627737	DLD1	viability	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.8598569866528851	[391]	[257,158,243]	8	hSpCas9	negative selection	827830
159209894	159209917	5	-	26627737	DLD1	viability	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-0.3383558438213832	[225]	[80,55,33]	-4	hSpCas9	negative selection	827831
159158741	159158764	5	-	26627737	GBM cells	viability after 5 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	-0.22753446035525338	[857]	[388,396]	-4	hSpCas9	negative selection	910142
159161472	159161495	5	+	26627737	GBM cells	viability after 5 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	-0.07745246861057975	[1331]	[692,660]	-1	hSpCas9	negative selection	910143
159203531	159203554	5	-	26627737	GBM cells	viability after 5 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.07018530203551454	[356]	[179,221]	1	hSpCas9	negative selection	910144
159209889	159209912	5	-	26627737	GBM cells	viability after 5 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.7534388244381333	[244]	[215,226]	8	hSpCas9	negative selection	910145
159209894	159209917	5	-	26627737	GBM cells	viability after 5 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-0.5521928791006803	[107]	[41,36]	-7	hSpCas9	negative selection	910146
159158741	159158764	5	-	26627737	GBM cells	viability after 13 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	-0.3575321350106475	[857]	[439,300]	-4	hSpCas9	negative selection	992457
159161472	159161495	5	+	26627737	GBM cells	viability after 13 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	-0.5925742192728889	[1331]	[620,363]	-6	hSpCas9	negative selection	992458
159203531	159203554	5	-	26627737	GBM cells	viability after 13 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	-0.027821532119704284	[356]	[189,189]	0	hSpCas9	negative selection	992459
159209889	159209912	5	-	26627737	GBM cells	viability after 13 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	1.0710305976650079	[244]	[361,211]	9	hSpCas9	negative selection	992460
159209894	159209917	5	-	26627737	GBM cells	viability after 13 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	0.04625418773407319	[107]	[38,77]	0	hSpCas9	negative selection	992461
159158741	159158764	5	-	26627737	GBM cells	viability after 21 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	-0.12062637075811944	[857]	[422,433]	-1	hSpCas9	negative selection	1074772
159161472	159161495	5	+	26627737	GBM cells	viability after 21 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	-0.7166928169299323	[1331]	[455,425]	-6	hSpCas9	negative selection	1074773
159203531	159203554	5	-	26627737	GBM cells	viability after 21 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	-0.46056416179181436	[356]	[153,128]	-4	hSpCas9	negative selection	1074774
159209889	159209912	5	-	26627737	GBM cells	viability after 21 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.589854040603117	[244]	[215,185]	6	hSpCas9	negative selection	1074775
159209894	159209917	5	-	26627737	GBM cells	viability after 21 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-0.41376605169099645	[107]	[42,44]	-4	hSpCas9	negative selection	1074776
159158741	159158764	5	-	26627737	RPE1	viability after 9 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.1228102513331717	[2374]	[582,1101]	0	hSpCas9	negative selection	1157087
159161472	159161495	5	+	26627737	RPE1	viability after 9 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.2880237726242427	[4564]	[1692,1811]	2	hSpCas9	negative selection	1157088
159203531	159203554	5	-	26627737	RPE1	viability after 9 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	-0.5808426018887152	[1337]	[214,363]	-4	hSpCas9	negative selection	1157089
159209889	159209912	5	-	26627737	RPE1	viability after 9 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	1.9333649789436445	[501]	[670,508]	8	hSpCas9	negative selection	1157090
159209894	159209917	5	-	26627737	RPE1	viability after 9 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-0.8907632540897766	[421]	[41,108]	-6	hSpCas9	negative selection	1157091
159158741	159158764	5	-	26627737	RPE1	viability after 12 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.31829907951384695	[2374]	[543,1061]	2	hSpCas9	negative selection	1239402
159161472	159161495	5	+	26627737	RPE1	viability after 12 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.28542144453078544	[4564]	[1435,1556]	2	hSpCas9	negative selection	1239403
159203531	159203554	5	-	26627737	RPE1	viability after 12 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	-0.32771938968364445	[1337]	[266,306]	-2	hSpCas9	negative selection	1239404
159209889	159209912	5	-	26627737	RPE1	viability after 12 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	2.237904419374517	[501]	[761,502]	9	hSpCas9	negative selection	1239405
159209894	159209917	5	-	26627737	RPE1	viability after 12 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-0.552857915264836	[421]	[35,120]	-4	hSpCas9	negative selection	1239406
159158741	159158764	5	-	26627737	RPE1	viability after 15 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.43936581676878794	[2374]	[853,965]	3	hSpCas9	negative selection	1321717
159161472	159161495	5	+	26627737	RPE1	viability after 15 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.26592279445167266	[4564]	[1568,1536]	1	hSpCas9	negative selection	1321718
159203531	159203554	5	-	26627737	RPE1	viability after 15 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	-0.6946138912332349	[1337]	[297,171]	-4	hSpCas9	negative selection	1321719
159209889	159209912	5	-	26627737	RPE1	viability after 15 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	1.9032588959064047	[501]	[492,567]	8	hSpCas9	negative selection	1321720
159209894	159209917	5	-	26627737	RPE1	viability after 15 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-0.34427541501029435	[421]	[35,149]	-2	hSpCas9	negative selection	1321721
159158741	159158764	5	-	26627737	RPE1	viability after 18 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.5870644170102401	[2374]	[796,1139]	3	hSpCas9	negative selection	1404032
159161472	159161495	5	+	26627737	RPE1	viability after 18 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.3147642294492403	[4564]	[1351,1724]	2	hSpCas9	negative selection	1404033
159203531	159203554	5	-	26627737	RPE1	viability after 18 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	-0.8171810621865123	[1337]	[202,206]	-5	hSpCas9	negative selection	1404034
159209889	159209912	5	-	26627737	RPE1	viability after 18 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	1.836507549016312	[501]	[449,519]	8	hSpCas9	negative selection	1404035
159209894	159209917	5	-	26627737	RPE1	viability after 18 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-0.45894749428571935	[421]	[63,102]	-3	hSpCas9	negative selection	1404036
159158741	159158764	5	-	26627737	HeLa	viability after 8 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.06313867678921836	[1502]	[1046,475,611]	0	hSpCas9	negative selection	1486347
159161472	159161495	5	+	26627737	HeLa	viability after 8 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.30533831064326256	[1791]	[1187,757,991]	3	hSpCas9	negative selection	1486348
159203531	159203554	5	-	26627737	HeLa	viability after 8 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.325362808262061	[555]	[397,209,320]	3	hSpCas9	negative selection	1486349
159209889	159209912	5	-	26627737	HeLa	viability after 8 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.16655800241930352	[344]	[120,219,154]	1	hSpCas9	negative selection	1486350
159209894	159209917	5	-	26627737	HeLa	viability after 8 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-0.45200448510973956	[159]	[16,73,53]	-4	hSpCas9	negative selection	1486351
159158741	159158764	5	-	26627737	HeLa	viability after 12 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	-0.660094451978946	[1502]	[264,463,438]	-5	hSpCas9	negative selection	1568662
159161472	159161495	5	+	26627737	HeLa	viability after 12 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.32957057794384736	[1791]	[714,1096,955]	3	hSpCas9	negative selection	1568663
159203531	159203554	5	-	26627737	HeLa	viability after 12 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.20039678780306658	[555]	[175,211,406]	1	hSpCas9	negative selection	1568664
159209889	159209912	5	-	26627737	HeLa	viability after 12 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.39369498684312043	[344]	[162,179,218]	3	hSpCas9	negative selection	1568665
159209894	159209917	5	-	26627737	HeLa	viability after 12 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-0.8856792910899876	[159]	[11,60,30]	-7	hSpCas9	negative selection	1568666
159158741	159158764	5	-	26627737	HeLa	viability after 15 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	-0.6574981366004555	[1502]	[520,337,295]	-5	hSpCas9	negative selection	1650977
159161472	159161495	5	+	26627737	HeLa	viability after 15 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.8123049981229298	[1791]	[1104,993,1784]	6	hSpCas9	negative selection	1650978
159203531	159203554	5	-	26627737	HeLa	viability after 15 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.3064711252854465	[555]	[299,313,220]	2	hSpCas9	negative selection	1650979
159209889	159209912	5	-	26627737	HeLa	viability after 15 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.8301021426940118	[344]	[278,143,331]	6	hSpCas9	negative selection	1650980
159209894	159209917	5	-	26627737	HeLa	viability after 15 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-2.326605617047383	[159]	[15,20,0]	-9	hSpCas9	negative selection	1650981
159158741	159158764	5	-	26627737	HeLa	viability after 18 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	-0.6831003367263553	[1502]	[336,278,295]	-5	hSpCas9	negative selection	1733292
159161472	159161495	5	+	26627737	HeLa	viability after 18 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.8050700024586797	[1791]	[728,822,1784]	6	hSpCas9	negative selection	1733293
159203531	159203554	5	-	26627737	HeLa	viability after 18 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.32571017433653104	[555]	[210,256,220]	2	hSpCas9	negative selection	1733294
159209889	159209912	5	-	26627737	HeLa	viability after 18 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.865926298476206	[344]	[197,120,331]	6	hSpCas9	negative selection	1733295
159209894	159209917	5	-	26627737	HeLa	viability after 18 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-2.0492641837131407	[159]	[13,19,0]	-9	hSpCas9	negative selection	1733296
159158741	159158764	5	-	26627737	HCT116	viability after 6 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	2.2934375405922216	[1773]	[924,1610]	9	hSpCas9	negative selection	1815607
159161472	159161495	5	+	26627737	HCT116	viability after 6 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	1.0739752593438192	[3009]	[1797,553]	6	hSpCas9	negative selection	1815608
159203531	159203554	5	-	26627737	HCT116	viability after 6 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	-1.5660081886580735	[1402]	[185,12]	-7	hSpCas9	negative selection	1815609
159209889	159209912	5	-	26627737	HCT116	viability after 6 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.24497578361217504	[451]	[167,37]	1	hSpCas9	negative selection	1815610
159209894	159209917	5	-	26627737	HCT116	viability after 6 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	1.5644054546264021	[162]	[20,105]	7	hSpCas9	negative selection	1815611
159158741	159158764	5	-	26627737	HCT116	viability after 8 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	1.014338791841751	[633]	[648,593,870]	8	hSpCas9	negative selection	1897922
159161472	159161495	5	+	26627737	HCT116	viability after 8 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.6607668359271726	[1245]	[970,1012,1267]	6	hSpCas9	negative selection	1897923
159203531	159203554	5	-	26627737	HCT116	viability after 8 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	-0.17275357470752384	[461]	[273,145,257]	-2	hSpCas9	negative selection	1897924
159209889	159209912	5	-	26627737	HCT116	viability after 8 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	-0.5865202523404515	[335]	[131,110,126]	-6	hSpCas9	negative selection	1897925
159209894	159209917	5	-	26627737	HCT116	viability after 8 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-1.7061053863106985	[134]	[10,18,37]	-9	hSpCas9	negative selection	1897926
159158741	159158764	5	-	26627737	HCT116	viability after 9 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.15735653093796254	[1773]	[682,405]	1	hSpCas9	negative selection	1980237
159161472	159161495	5	+	26627737	HCT116	viability after 9 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.47694844564837524	[3009]	[940,1258]	3	hSpCas9	negative selection	1980238
159203531	159203554	5	-	26627737	HCT116	viability after 9 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	-0.45883938439505656	[1402]	[290,257]	-3	hSpCas9	negative selection	1980239
159209889	159209912	5	-	26627737	HCT116	viability after 9 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	1.4750379138904968	[451]	[301,361]	8	hSpCas9	negative selection	1980240
159209894	159209917	5	-	26627737	HCT116	viability after 9 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	0.0747287460566406	[162]	[13,70]	0	hSpCas9	negative selection	1980241
159158741	159158764	5	-	26627737	HCT116	viability after 12 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.5520826019776355	[633]	[428,497,543]	5	hSpCas9	negative selection	2062552
159161472	159161495	5	+	26627737	HCT116	viability after 12 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.5543073022261158	[1245]	[778,890,1228]	5	hSpCas9	negative selection	2062553
159203531	159203554	5	-	26627737	HCT116	viability after 12 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.2920647045609339	[461]	[382,243,255]	3	hSpCas9	negative selection	2062554
159209889	159209912	5	-	26627737	HCT116	viability after 12 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.2396133842347539	[335]	[255,114,247]	2	hSpCas9	negative selection	2062555
159209894	159209917	5	-	26627737	HCT116	viability after 12 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-0.44497914120576554	[134]	[59,24,69]	-5	hSpCas9	negative selection	2062556
159158741	159158764	5	-	26627737	HCT116	viability after 15 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	1.0650503980649997	[633]	[837,640,814]	8	hSpCas9	negative selection	2144867
159161472	159161495	5	+	26627737	HCT116	viability after 15 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.713066688584151	[1245]	[981,1105,1404]	6	hSpCas9	negative selection	2144868
159203531	159203554	5	-	26627737	HCT116	viability after 15 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.0237801686821405	[461]	[406,156,261]	0	hSpCas9	negative selection	2144869
159209889	159209912	5	-	26627737	HCT116	viability after 15 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.6088145142396518	[335]	[242,291,340]	5	hSpCas9	negative selection	2144870
159209894	159209917	5	-	26627737	HCT116	viability after 15 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-0.3463469557148746	[134]	[57,97,26]	-4	hSpCas9	negative selection	2144871
159158741	159158764	5	-	26627737	HCT116	viability after 18 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	1.219873009946648	[633]	[525,917,682]	8	hSpCas9	negative selection	2227182
159161472	159161495	5	+	26627737	HCT116	viability after 18 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.7739649546264005	[1245]	[801,1124,1162]	6	hSpCas9	negative selection	2227183
159203531	159203554	5	-	26627737	HCT116	viability after 18 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.31561076990958903	[461]	[333,142,369]	2	hSpCas9	negative selection	2227184
159209889	159209912	5	-	26627737	HCT116	viability after 18 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.8772623446025445	[335]	[196,366,327]	7	hSpCas9	negative selection	2227185
159209894	159209917	5	-	26627737	HCT116	viability after 18 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	0.10677605543319846	[134]	[52,75,81]	0	hSpCas9	negative selection	2227186
159186888	159186911	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATCACTTGAGCCCTGG	RNF145	ENSG00000145860	1.6338811116880798	[2,7]	[1,4]	6	dCas9-VP64	positive selection	2394934
159190066	159190089	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGGTCTTGTTCTGTCACCAGG	RNF145	ENSG00000145860	1.8873495753995055	[277,92]	[61,243]	6	dCas9-VP64	positive selection	2402525
159165531	159165554	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAATTAGCCGGGCGTAGTGGCGG	RNF145	ENSG00000145860	-0.8514681672512537	[13,97]	[5,6]	-5	dCas9-VP64	positive selection	2404275
159208296	159208319	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACCCTTGGCGAGATAGGAGGGG	RNF145	ENSG00000145860	-1.4752272356787817	[196,18]	[5,9]	-8	dCas9-VP64	positive selection	2410397
159208256	159208279	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGTTCAGCAAAAACTCTTCCAGG	RNF145	ENSG00000145860	-1.4652217667269372	[91,275]	[9,19]	-8	dCas9-VP64	positive selection	2410398
159208274	159208297	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGCTCTCGAGCCTCTTTCCTGG	RNF145	ENSG00000145860	-1.6423371715481	[163,108]	[11,5]	-8	dCas9-VP64	positive selection	2410399
159207798	159207821	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATCTCCCAAACCGCAAAGACAGG	RNF145	ENSG00000145860	2.065937932651203	[16,50]	[16,45]	7	dCas9-VP64	positive selection	2410400
159207820	159207843	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTACTCTGAATACAAAGG	RNF145	ENSG00000145860	1.3214681371076005	[137,279]	[159,68]	5	dCas9-VP64	positive selection	2410401
159207754	159207777	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	TAGTAGTTTATGTGGAGATCAGG	RNF145	ENSG00000145860	-0.381987828270558	[118,80]	[24,6]	-2	dCas9-VP64	positive selection	2410402
159209651	159209674	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGGTGCGGAAAGCACTCCGCGGG	RNF145	ENSG00000145860	-1.580019118556653	[399,72]	[30,1]	-8	dCas9-VP64	positive selection	2410403
159209703	159209726	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTAGCCAAGCCCATACAGCCCGG	RNF145	ENSG00000145860	-0.29367914225249725	[126,64]	[25,6]	-1	dCas9-VP64	positive selection	2410404
159209721	159209744	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCCATAGCCACCCGAGCCGGG	RNF145	ENSG00000145860	-0.8915876972620331	[140,228]	[34,6]	-5	dCas9-VP64	positive selection	2410405
159207900	159207923	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGTCGTGACCCAGGCTGAGCGG	RNF145	ENSG00000145860	0.6469831363910472	[295,187]	[55,111]	2	dCas9-VP64	positive selection	2465503
159207925	159207948	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCACCGACAGCTCATTCTTTTGG	RNF145	ENSG00000145860	-0.6852914912764261	[142,76]	[5,23]	-3	dCas9-VP64	positive selection	2465504
159207887	159207910	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCTGAGCGGCCGATGGCAGAGG	RNF145	ENSG00000145860	2.4233407576453243	[48,44]	[96,11]	7	dCas9-VP64	positive selection	2465505
159186888	159186911	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATCACTTGAGCCCTGG	RNF145	ENSG00000145860	0.9117627085384212	[38,78]	[28,41]	6	dCas9-VP64	positive selection	2490189
159190066	159190089	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGGTCTTGTTCTGTCACCAGG	RNF145	ENSG00000145860	-0.6627118139888153	[169,193]	[38,34]	-6	dCas9-VP64	positive selection	2497780
159165531	159165554	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAATTAGCCGGGCGTAGTGGCGG	RNF145	ENSG00000145860	0.40157018881037165	[169,39]	[83,8]	3	dCas9-VP64	positive selection	2499530
159208296	159208319	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACCCTTGGCGAGATAGGAGGGG	RNF145	ENSG00000145860	-0.10161299245994804	[42,53]	[16,11]	-1	dCas9-VP64	positive selection	2505652
159208256	159208279	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGTTCAGCAAAAACTCTTCCAGG	RNF145	ENSG00000145860	0.5184734557595434	[57,48]	[19,28]	4	dCas9-VP64	positive selection	2505653
159208274	159208297	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGCTCTCGAGCCTCTTTCCTGG	RNF145	ENSG00000145860	0.4696409919588288	[106,275]	[39,127]	3	dCas9-VP64	positive selection	2505654
159207798	159207821	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATCTCCCAAACCGCAAAGACAGG	RNF145	ENSG00000145860	-0.09324396745501518	[111,389]	[78,72]	0	dCas9-VP64	positive selection	2505655
159207820	159207843	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTACTCTGAATACAAAGG	RNF145	ENSG00000145860	0.16154368240754424	[189,296]	[90,85]	1	dCas9-VP64	positive selection	2505656
159207754	159207777	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	TAGTAGTTTATGTGGAGATCAGG	RNF145	ENSG00000145860	-0.8624282271352351	[42,89]	[11,10]	-7	dCas9-VP64	positive selection	2505657
159209651	159209674	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGGTGCGGAAAGCACTCCGCGGG	RNF145	ENSG00000145860	0.9386043131635127	[30,40]	[12,30]	6	dCas9-VP64	positive selection	2505658
159209703	159209726	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTAGCCAAGCCCATACAGCCCGG	RNF145	ENSG00000145860	2.640648257454072	[65,54]	[237,16]	9	dCas9-VP64	positive selection	2505659
159209721	159209744	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCCATAGCCACCCGAGCCGGG	RNF145	ENSG00000145860	0.2361661114755662	[165,266]	[57,105]	2	dCas9-VP64	positive selection	2505660
159207900	159207923	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGTCGTGACCCAGGCTGAGCGG	RNF145	ENSG00000145860	-0.33529151375089217	[65,146]	[23,29]	-3	dCas9-VP64	positive selection	2560758
159207925	159207948	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCACCGACAGCTCATTCTTTTGG	RNF145	ENSG00000145860	-1.4407134332895422	[211,205]	[27,21]	-9	dCas9-VP64	positive selection	2560759
159207887	159207910	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCTGAGCGGCCGATGGCAGAGG	RNF145	ENSG00000145860	0.34898577279672083	[67,28]	[16,22]	3	dCas9-VP64	positive selection	2560760
159174100	159174123	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACTACCAGTTGATTCCACAGGG	RNF145	ENSG00000145860	-0.007520942773738548	[4,5]	[3,4]	0	hSpCas9	positive selection	3017189
159169733	159169756	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGAGTGTGAGAACACCCAAGG	RNF145	ENSG00000145860	-0.8649156635323046	[2,2]	[1,0]	-8	hSpCas9	positive selection	3017190
159181975	159181998	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	-0.06411195735711037	[4,4]	[3,3]	-1	hSpCas9	positive selection	3017191
159203530	159203553	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGGATGTCCTGTACAGATGGG	RNF145	ENSG00000145860	0.27319518587318325	[4,4]	[4,5]	6	hSpCas9	positive selection	3017192
159174100	159174123	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACTACCAGTTGATTCCACAGGG	RNF145	ENSG00000145860	0.21183692066503518	[4,4]	[4,3]	4	hSpCas9	positive selection	3085047
159169733	159169756	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGAGTGTGAGAACACCCAAGG	RNF145	ENSG00000145860	-0.9259996203349457	[2,2]	[0,0]	-9	hSpCas9	positive selection	3085048
159181975	159181998	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	-0.40377602956451886	[4,4]	[1,2]	-6	hSpCas9	positive selection	3085049
159203530	159203553	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGGATGTCCTGTACAGATGGG	RNF145	ENSG00000145860	0.5170920313707008	[4,4]	[4,4]	8	hSpCas9	positive selection	3085050
159203544	159203567		+	24336571	A375	resistance to PLX after 7 days	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.3090679398188909	[119,113]	[96,90]	-8	hSpCas9	positive selection	3141251
159203449	159203472		+	24336571	A375	resistance to PLX after 7 days	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.28846436067099146	[21,27]	[32,27]	7	hSpCas9	positive selection	3141252
159194807	159194830		-	24336571	A375	resistance to PLX after 7 days	TACAGGTTATATCTTAAGTGTGG	RNF145	ENSG00000145860	-0.2680721227538454	[53,44]	[40,39]	-7	hSpCas9	positive selection	3141253
159203544	159203567		+	24336571	A375	resistance to PLX after 14 days	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.46887179974320725	[130,105]	[34,44]	-5	hSpCas9	positive selection	3199044
159203449	159203472		+	24336571	A375	resistance to PLX after 14 days	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.6780946048194165	[21,27]	[20,15]	6	hSpCas9	positive selection	3199045
159194807	159194830		-	24336571	A375	resistance to PLX after 14 days	TACAGGTTATATCTTAAGTGTGG	RNF145	ENSG00000145860	-0.6553143439306233	[37,51]	[13,11]	-7	hSpCas9	positive selection	3199046
159203544	159203567		+	24336571	A375	viability after 7 days	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.7777937244629047	[71]	[119,113]	9	hSpCas9	negative selection	3256837
159203449	159203472		+	24336571	A375	viability after 7 days	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.7510556422975417	[43]	[21,27]	-8	hSpCas9	negative selection	3256838
159194807	159194830		-	24336571	A375	viability after 7 days	TACAGGTTATATCTTAAGTGTGG	RNF145	ENSG00000145860	-0.3191796655464596	[64]	[53,44]	-4	hSpCas9	negative selection	3256839
159203544	159203567		+	24336571	A375	viability after 14 days	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.8133479545886209	[71]	[130,105]	8	hSpCas9	negative selection	3314630
159203449	159203472		+	24336571	A375	viability after 14 days	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.7192445288538596	[43]	[21,27]	-7	hSpCas9	negative selection	3314631
159194807	159194830		-	24336571	A375	viability after 14 days	TACAGGTTATATCTTAAGTGTGG	RNF145	ENSG00000145860	-0.4255415764152617	[64]	[37,51]	-5	hSpCas9	negative selection	3314632
159207762	159207785	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.7199537120540815	[251,251]	[0,0]	-5	hSpCas9	positive selection	3390100
159203544	159203567	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.8822251409529586	[281,281]	[0,0]	-6	hSpCas9	positive selection	3390101
159203578	159203601	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	0.7495315712471388	[90,90]	[0,0]	3	hSpCas9	positive selection	3390102
159174099	159174122	5	+	26780180	HT29	viability (Avana library 4 designs)	GACTACCAGTTGATTCCACAGGG	RNF145	ENSG00000145860	0.748442406019111	[]	[]	3	hSpCas9	negative selection	3455560
159169732	159169755	5	+	26780180	HT29	viability (Avana library 4 designs)	GCAGAGTGTGAGAACACCCAAGG	RNF145	ENSG00000145860	1.51328679547218	[]	[]	6	hSpCas9	negative selection	3455561
159181974	159181997	5	+	26780180	HT29	viability (Avana library 4 designs)	GTAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	1.96170160532016	[]	[]	7	hSpCas9	negative selection	3455562
159203530	159203553	5	-	26780180	HT29	viability (Avana library 4 designs)	GTTGGATGTCCTGTACAGATGGG	RNF145	ENSG00000145860	0.7951652565275	[]	[]	3	hSpCas9	negative selection	3455563
159174099	159174122	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACTACCAGTTGATTCCACAGGG	RNF145	ENSG00000145860	-0.948507864064498	[]	[]	-1	hSpCas9	negative selection	3553610
159181974	159181997	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	-2.99861590626901	[]	[]	-4	hSpCas9	negative selection	3553611
159169732	159169755	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGAGTGTGAGAACACCCAAGG	RNF145	ENSG00000145860	-0.768439251110331	[]	[]	-1	hSpCas9	negative selection	3553612
159203530	159203553	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGGATGTCCTGTACAGATGGG	RNF145	ENSG00000145860	2.6580714969264	[]	[]	4	hSpCas9	negative selection	3553613
159176768	159176791	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGCAGAGTCGTGCTAGCAGAGG	RNF145	ENSG00000145860	-11.6970550532466	[]	[]	-8	hSpCas9	negative selection	3553614
159169678	159169701	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAATGATCCTGCCATGAATCGG	RNF145	ENSG00000145860	-3.79927835294895	[]	[]	-4	hSpCas9	negative selection	3553615
159174099	159174122	5	+	26780180	A375	viability (Avana lentiGuide)	GACTACCAGTTGATTCCACAGGG	RNF145	ENSG00000145860	2.5945663750681	[]	[]	2	hSpCas9	negative selection	3662269
159181974	159181997	5	+	26780180	A375	viability (Avana lentiGuide)	GTAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	2.47554637371521	[]	[]	2	hSpCas9	negative selection	3662270
159169732	159169755	5	+	26780180	A375	viability (Avana lentiGuide)	GCAGAGTGTGAGAACACCCAAGG	RNF145	ENSG00000145860	7.43860263928124	[]	[]	6	hSpCas9	negative selection	3662271
159203530	159203553	5	-	26780180	A375	viability (Avana lentiGuide)	GTTGGATGTCCTGTACAGATGGG	RNF145	ENSG00000145860	-3.54403185246541	[]	[]	-6	hSpCas9	negative selection	3662272
159176768	159176791	5	+	26780180	A375	viability (Avana lentiGuide)	AGGCAGAGTCGTGCTAGCAGAGG	RNF145	ENSG00000145860	13.63872216233	[]	[]	7	hSpCas9	negative selection	3662273
159169678	159169701	5	-	26780180	A375	viability (Avana lentiGuide)	TGAATGATCCTGCCATGAATCGG	RNF145	ENSG00000145860	4.47350879766897	[]	[]	4	hSpCas9	negative selection	3662274
159174099	159174122	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACTACCAGTTGATTCCACAGGG	RNF145	ENSG00000145860	-0.28555288822997493	[6]	[5,4]	-4	hSpCas9	positive selection	3770876
159181974	159181997	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	-0.28101547986212266	[6]	[5,4]	-4	hSpCas9	positive selection	3770877
159169732	159169755	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGAGTGTGAGAACACCCAAGG	RNF145	ENSG00000145860	-0.017762095854069126	[4]	[4,3]	0	hSpCas9	positive selection	3770878
159203530	159203553	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGGATGTCCTGTACAGATGGG	RNF145	ENSG00000145860	0.19908978024099713	[5]	[6,6]	5	hSpCas9	positive selection	3770879
159176768	159176791	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGCAGAGTCGTGCTAGCAGAGG	RNF145	ENSG00000145860	-1.2644151684430986	[4]	[1,0]	-9	hSpCas9	positive selection	3770880
159169678	159169701	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAATGATCCTGCCATGAATCGG	RNF145	ENSG00000145860	-0.4549686495325689	[6]	[4,3]	-6	hSpCas9	positive selection	3770881
159174099	159174122	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACTACCAGTTGATTCCACAGGG	RNF145	ENSG00000145860	0.13555867782895792	[6]	[6,6]	3	hSpCas9	positive selection	3879483
159181974	159181997	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	-0.4717871062337055	[6]	[2,3]	-6	hSpCas9	positive selection	3879484
159169732	159169755	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGAGTGTGAGAACACCCAAGG	RNF145	ENSG00000145860	-0.3092761662329657	[4]	[4,0]	-4	hSpCas9	positive selection	3879485
159203530	159203553	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGGATGTCCTGTACAGATGGG	RNF145	ENSG00000145860	0.2573381482327194	[6]	[6,6]	7	hSpCas9	positive selection	3879486
159176768	159176791	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGCAGAGTCGTGCTAGCAGAGG	RNF145	ENSG00000145860	-0.7303576879534222	[5]	[2,2]	-7	hSpCas9	positive selection	3879487
159169678	159169701	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAATGATCCTGCCATGAATCGG	RNF145	ENSG00000145860	-0.3938817103149589	[5]	[3,3]	-5	hSpCas9	positive selection	3879488
159203544	159203567	5	+	26780180	A375	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.510650870536926	[]	[]	1	hSpCas9	negative selection	3989600
159203578	159203601	5	-	26780180	A375	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	0.691863901790296	[]	[]	2	hSpCas9	negative selection	3989601
159207762	159207785	5	-	26780180	A375	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.880885052445143	[]	[]	3	hSpCas9	negative selection	3989602
159203521	159203544	5	+	26780180	A375	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.757557381997819	[]	[]	3	hSpCas9	negative selection	3989603
159207766	159207789	5	+	26780180	A375	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.967655925267728	[]	[]	4	hSpCas9	negative selection	3989604
159203449	159203472	5	+	26780180	A375	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.816705066768838	[]	[]	3	hSpCas9	negative selection	3989605
159203544	159203567	5	+	26780180	HT29	viability (GeCKOv2 library)	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.411178435137746	[]	[]	1	hSpCas9	negative selection	4097566
159203578	159203601	5	-	26780180	HT29	viability (GeCKOv2 library)	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	0.867115856539012	[]	[]	3	hSpCas9	negative selection	4097567
159207762	159207785	5	-	26780180	HT29	viability (GeCKOv2 library)	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.783165519080878	[]	[]	3	hSpCas9	negative selection	4097568
159203521	159203544	5	+	26780180	HT29	viability (GeCKOv2 library)	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.893024875299965	[]	[]	4	hSpCas9	negative selection	4097569
159207766	159207789	5	+	26780180	HT29	viability (GeCKOv2 library)	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.337054763432983	[]	[]	0	hSpCas9	negative selection	4097570
159203449	159203472	5	+	26780180	HT29	viability (GeCKOv2 library)	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	1.58806145899066	[]	[]	8	hSpCas9	negative selection	4097571
159203544	159203567	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.15666475604329577	[6]	[4,5]	4	hSpCas9	positive selection	4166775
159203449	159203472	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.14238387397014593	[4]	[2,4]	3	hSpCas9	positive selection	4166776
159194807	159194830	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACAGGTTATATCTTAAGTGTGG	RNF145	ENSG00000145860	0.07952686167868428	[5]	[4,3]	2	hSpCas9	positive selection	4166777
159203544	159203567	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	1.1481385578036376	[5]	[5,5,4,5]	8	hSpCas9	positive selection	4230797
159203449	159203472	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.46388027649649416	[4]	[3,3,4,0]	3	hSpCas9	positive selection	4230798
159194807	159194830	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACAGGTTATATCTTAAGTGTGG	RNF145	ENSG00000145860	1.2551801086370533	[4]	[4,3,5,4]	9	hSpCas9	positive selection	4230799
159203449	159203472	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.19087745266492578	[1]	[1,0]	-4	hSpCas9	positive selection	4295163
159203521	159203544	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.5409391813556408	[2]	[3,3]	9	hSpCas9	positive selection	4295164
159207766	159207789	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.010906331081322579	[3]	[3,1]	0	hSpCas9	positive selection	4295165
159207762	159207785	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.21261768008151505	[3]	[2,2]	4	hSpCas9	positive selection	4359417
159203544	159203567	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.14132821310515148	[4]	[4,3]	3	hSpCas9	positive selection	4359418
159203578	159203601	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.1854498668081644	[2]	[3,0]	-4	hSpCas9	positive selection	4359419
159169671	159169693	5	+	27760321	OCIAML3	viability	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	-0.2989367602544045	[621,507]	[326,396]	-3	hSpCas9	negative selection	4435088
159174025	159174047	5	+	27760321	OCIAML3	viability	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	-0.4973764777008003	[126,100]	[57,68]	-5	hSpCas9	negative selection	4435089
159174128	159174150	5	-	27760321	OCIAML3	viability	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	0.7849687314285826	[769,708]	[939,1069]	8	hSpCas9	negative selection	4435090
159181953	159181975	5	+	27760321	OCIAML3	viability	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	2.6583508348088762	[30,29]	[103,211]	9	hSpCas9	negative selection	4435091
159181975	159181997	5	+	27760321	OCIAML3	viability	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	-1.9218491327502059	[66,42]	[18,0]	-9	hSpCas9	negative selection	4435092
159169671	159169693	5	+	27760321	OCIAML2	viability	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	-0.8547886824283882	[621,507]	[203,313]	-7	hSpCas9	negative selection	4518551
159174025	159174047	5	+	27760321	OCIAML2	viability	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	-0.6108523410371092	[126,100]	[56,63]	-6	hSpCas9	negative selection	4518552
159174128	159174150	5	-	27760321	OCIAML2	viability	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	0.42672100559631987	[769,708]	[693,948]	6	hSpCas9	negative selection	4518553
159181953	159181975	5	+	27760321	OCIAML2	viability	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	-3.1918375933148733	[30,29]	[3,0]	-9	hSpCas9	negative selection	4518554
159181975	159181997	5	+	27760321	OCIAML2	viability	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	-1.652463118290449	[66,42]	[0,30]	-8	hSpCas9	negative selection	4518555
159169671	159169693	5	+	27760321	MV411	viability	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	0.26038390486179164	[621,507]	[636,154]	1	hSpCas9	negative selection	4602014
159174025	159174047	5	+	27760321	MV411	viability	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	-2.662973079429359	[126,100]	[18,0]	-9	hSpCas9	negative selection	4602015
159174128	159174150	5	-	27760321	MV411	viability	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	0.5789377850649869	[769,708]	[572,962]	4	hSpCas9	negative selection	4602016
159181953	159181975	5	+	27760321	MV411	viability	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	-0.7742328245295651	[30,29]	[0,27]	-5	hSpCas9	negative selection	4602017
159181975	159181997	5	+	27760321	MV411	viability	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	0.18246447615149597	[66,42]	[22,66]	1	hSpCas9	negative selection	4602018
159169671	159169693	5	+	27760321	HL60	viability	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	-0.39681820265544865	[621,507]	[308,390]	-4	hSpCas9	negative selection	4685477
159174025	159174047	5	+	27760321	HL60	viability	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	-1.0281462780125734	[126,100]	[24,66]	-7	hSpCas9	negative selection	4685478
159174128	159174150	5	-	27760321	HL60	viability	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	-0.05349305274468397	[769,708]	[549,615]	0	hSpCas9	negative selection	4685479
159181953	159181975	5	+	27760321	HL60	viability	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	-0.7081183969269214	[30,29]	[7,22]	-6	hSpCas9	negative selection	4685480
159181975	159181997	5	+	27760321	HL60	viability	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	0.08359438406884978	[66,42]	[43,49]	1	hSpCas9	negative selection	4685481
159169671	159169693	5	+	27760321	HT1080	viability	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	-0.5045988961233124	[507,396]	[117,136]	-2	hSpCas9	negative selection	4768940
159174025	159174047	5	+	27760321	HT1080	viability	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	0.3249376124434169	[100,78]	[0,92]	1	hSpCas9	negative selection	4768941
159174128	159174150	5	-	27760321	HT1080	viability	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	0.028829551075817084	[708,552]	[233,280]	0	hSpCas9	negative selection	4768942
159181953	159181975	5	+	27760321	HT1080	viability	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	1.1554732953740072	[29,23]	[44,0]	6	hSpCas9	negative selection	4768943
159181975	159181997	5	+	27760321	HT1080	viability	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	2.6802079259702807	[42,33]	[116,77]	9	hSpCas9	negative selection	4768944
159169671	159169693	5	+	27760321	HT29	viability after 7 days	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	-0.9429908673134559	[507,396]	[333,371,208]	-8	hSpCas9	negative selection	4852403
159174025	159174047	5	+	27760321	HT29	viability after 7 days	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	-0.8535603760596902	[100,78]	[102,74,20]	-8	hSpCas9	negative selection	4852404
159174128	159174150	5	-	27760321	HT29	viability after 7 days	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	0.1729924371568231	[708,552]	[907,1028,807]	2	hSpCas9	negative selection	4852405
159181953	159181975	5	+	27760321	HT29	viability after 7 days	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	-0.4212507035811761	[29,23]	[0,37,34]	-6	hSpCas9	negative selection	4852406
159181975	159181997	5	+	27760321	HT29	viability after 7 days	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	-1.0607262531382409	[42,33]	[22,20,26]	-8	hSpCas9	negative selection	4852407
159169671	159169693	5	+	27760321	HT29	viability after 25 days	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	-0.08727744383046576	[507,396]	[643,411,382]	-1	hSpCas9	negative selection	4935866
159174025	159174047	5	+	27760321	HT29	viability after 25 days	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	-0.8295726522781	[100,78]	[73,53,42]	-6	hSpCas9	negative selection	4935867
159174128	159174150	5	-	27760321	HT29	viability after 25 days	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	0.3716900785799572	[708,552]	[1031,837,919]	4	hSpCas9	negative selection	4935868
159181953	159181975	5	+	27760321	HT29	viability after 25 days	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	0.19576223392118752	[29,23]	[8,52,46]	2	hSpCas9	negative selection	4935869
159181975	159181997	5	+	27760321	HT29	viability after 25 days	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	-0.006956010469724383	[42,33]	[42,82,0]	0	hSpCas9	negative selection	4935870
159169671	159169693	5	+	27760321	HT29	viability after 22 days	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	-0.1394191814962712	[507,396]	[503,558,359]	-1	hSpCas9	negative selection	5019329
159174025	159174047	5	+	27760321	HT29	viability after 22 days	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	-1.1700441305769302	[100,78]	[98,23,13]	-7	hSpCas9	negative selection	5019330
159174128	159174150	5	-	27760321	HT29	viability after 22 days	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	0.25585979976226103	[708,552]	[1006,651,950]	2	hSpCas9	negative selection	5019331
159181953	159181975	5	+	27760321	HT29	viability after 22 days	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	-0.49892352807974927	[29,23]	[7,9,48]	-4	hSpCas9	negative selection	5019332
159181975	159181997	5	+	27760321	HT29	viability after 22 days	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	-0.28644242306826984	[42,33]	[7,100,0]	-3	hSpCas9	negative selection	5019333
159169671	159169693	5	+	27760321	HT29	viability after 19 days	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	-0.3644915813249923	[507,396]	[527,504,193]	-3	hSpCas9	negative selection	5102792
159174025	159174047	5	+	27760321	HT29	viability after 19 days	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	-2.946633774430473	[100,78]	[29,3,7]	-8	hSpCas9	negative selection	5102793
159174128	159174150	5	-	27760321	HT29	viability after 19 days	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	0.9854728908114404	[708,552]	[1432,1078,1760]	8	hSpCas9	negative selection	5102794
159181953	159181975	5	+	27760321	HT29	viability after 19 days	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	-3.044969512724319	[29,23]	[9,0,0]	-8	hSpCas9	negative selection	5102795
159181975	159181997	5	+	27760321	HT29	viability after 19 days	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	0.6230809951680869	[42,33]	[75,102,26]	6	hSpCas9	negative selection	5102796
159169671	159169693	5	+	27760321	HT29	viability after 16 days	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	-0.5799631055193188	[507,396]	[506,183,344]	-5	hSpCas9	negative selection	5186255
159174025	159174047	5	+	27760321	HT29	viability after 16 days	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	-2.150871855858189	[100,78]	[41,16,10]	-8	hSpCas9	negative selection	5186256
159174128	159174150	5	-	27760321	HT29	viability after 16 days	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	0.2685558399606537	[708,552]	[1201,704,680]	3	hSpCas9	negative selection	5186257
159181953	159181975	5	+	27760321	HT29	viability after 16 days	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	0.7587669740064791	[29,23]	[9,76,61]	8	hSpCas9	negative selection	5186258
159181975	159181997	5	+	27760321	HT29	viability after 16 days	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	-1.6338585040701092	[42,33]	[27,13,0]	-8	hSpCas9	negative selection	5186259
159169671	159169693	5	+	27760321	HT29	viability after 13 days	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	-0.29364414526810795	[507,396]	[363,577,347]	-4	hSpCas9	negative selection	5269718
159174025	159174047	5	+	27760321	HT29	viability after 13 days	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	-2.128843836835305	[100,78]	[19,16,33]	-8	hSpCas9	negative selection	5269719
159174128	159174150	5	-	27760321	HT29	viability after 13 days	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	0.09821414036946752	[708,552]	[1094,729,539]	1	hSpCas9	negative selection	5269720
159181953	159181975	5	+	27760321	HT29	viability after 13 days	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	0.19763257123473998	[29,23]	[80,10,16]	2	hSpCas9	negative selection	5269721
159181975	159181997	5	+	27760321	HT29	viability after 13 days	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	0.1166242385308145	[42,33]	[10,77,55]	1	hSpCas9	negative selection	5269722
159169671	159169693	5	+	27760321	HT29	viability after 10 days	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	-0.604664557496565	[507,396]	[553,276,282]	-6	hSpCas9	negative selection	5353181
159174025	159174047	5	+	27760321	HT29	viability after 10 days	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	-2.2785932279035617	[100,78]	[10,58,0]	-9	hSpCas9	negative selection	5353182
159174128	159174150	5	-	27760321	HT29	viability after 10 days	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	-0.03401797380487137	[708,552]	[723,604,969]	0	hSpCas9	negative selection	5353183
159181953	159181975	5	+	27760321	HT29	viability after 10 days	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	0.024111639644475158	[29,23]	[57,43,1]	0	hSpCas9	negative selection	5353184
159181975	159181997	5	+	27760321	HT29	viability after 10 days	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	0.05817886363757596	[42,33]	[105,39,4]	0	hSpCas9	negative selection	5353185
159169671	159169693	5	+	27760321	MOLM13	viability	GAACTTACCGATTCATGGCAGG	RNF145	ENSG00000145860	-1.800999214832823	[621,507]	[83,96]	-7	hSpCas9	negative selection	5436644
159174025	159174047	5	+	27760321	MOLM13	viability	TGATCTCGAGTACTGAAATAGG	RNF145	ENSG00000145860	-1.1152269815735147	[126,100]	[62,0]	-6	hSpCas9	negative selection	5436645
159174128	159174150	5	-	27760321	MOLM13	viability	GTATATGGCCTTCTCGCCTTGG	RNF145	ENSG00000145860	0.11374976727723352	[769,708]	[640,289]	0	hSpCas9	negative selection	5436646
159181953	159181975	5	+	27760321	MOLM13	viability	TACTTACCTATTAAGGCTGTGG	RNF145	ENSG00000145860	-4.107795664308663	[30,29]	[0,0]	-9	hSpCas9	negative selection	5436647
159181975	159181997	5	+	27760321	MOLM13	viability	TAAACCGATTCATAGAGAGAGG	RNF145	ENSG00000145860	-4.934367862361164	[66,42]	[0,0]	-9	hSpCas9	negative selection	5436648
159207820	159207843	5	+	27661255	K562	viability	GGAGTCTACTCTGAATACAAAGG	RNF145	ENSG00000145860	-0.17554448207051654	[1167,1108]	[839,776]	-5	dCas9-KRAB	negative selection	5507844
159209088	159209111	5	+	27661255	K562	viability	GGGAGGTGAAGCGAGATAAAAGG	RNF145	ENSG00000145860	-0.16667756074046242	[867,675]	[580,526]	-5	dCas9-KRAB	negative selection	5507845
159209473	159209496	5	+	27661255	K562	viability	GGGCCGAGCCCCTTAGCAGCCGG	RNF145	ENSG00000145860	0.5164803798142095	[177,221]	[252,205]	9	dCas9-KRAB	negative selection	5507846
159208069	159208092	5	-	27661255	K562	viability	GAGCAGGCATCAAAGATTAGTGG	RNF145	ENSG00000145860	-0.24402843788922318	[1016,803]	[694,549]	-6	dCas9-KRAB	negative selection	5507847
159209520	159209543	5	-	27661255	K562	viability	GGGGCGGGAGGAGCAAACGCAGG	RNF145	ENSG00000145860	0.0717656458362248	[1024,1190]	[1039,831]	2	dCas9-KRAB	negative selection	5507848
159203449	159203472	5	+	27260156	BXPC3	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.12843629467442685	[172]	[127,221,220,228]	3	hSpCas9	negative selection	5567623
159203521	159203544	5	+	27260156	BXPC3	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.607132274122907	[392]	[489,660,703,662]	9	hSpCas9	negative selection	5567624
159207766	159207789	5	+	27260156	BXPC3	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.08783294622018961	[559]	[491,613,659,749]	2	hSpCas9	negative selection	5567625
159207762	159207785	5	-	27260156	BXPC3	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.10118655536095095	[571]	[531,556,722,785]	2	hSpCas9	negative selection	5631877
159203544	159203567	5	+	27260156	BXPC3	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.09393994706840259	[1501]	[1321,1292,1530,1797]	-2	hSpCas9	negative selection	5631878
159203578	159203601	5	-	27260156	BXPC3	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.12709997273831258	[350]	[265,355,409,314]	-3	hSpCas9	negative selection	5631879
159203449	159203472	5	+	27260156	A673	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.04240992191002757	[172]	[214,230,225,180]	1	hSpCas9	negative selection	5688874
159203521	159203544	5	+	27260156	A673	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.4650307613947272	[392]	[689,641,597,680]	9	hSpCas9	negative selection	5688875
159207766	159207789	5	+	27260156	A673	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.022142403923240184	[559]	[717,610,656,753]	0	hSpCas9	negative selection	5688876
159207762	159207785	5	-	27260156	A673	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.04159034698970129	[571]	[926,629,600,533]	-1	hSpCas9	negative selection	5753128
159203544	159203567	5	+	27260156	A673	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.09543725268591641	[1501]	[1823,1554,1844,1533]	-2	hSpCas9	negative selection	5753129
159203578	159203601	5	-	27260156	A673	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.18657865964302706	[350]	[421,347,380,333]	-5	hSpCas9	negative selection	5753130
159203449	159203472	5	+	27260156	A375	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.44524172403737006	[172]	[162,124,98,196]	-6	hSpCas9	negative selection	5810125
159203521	159203544	5	+	27260156	A375	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.2799357628254036	[392]	[522,685,480,554]	4	hSpCas9	negative selection	5810126
159207766	159207789	5	+	27260156	A375	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.11499679202845003	[559]	[799,832,630,597]	1	hSpCas9	negative selection	5810127
159207762	159207785	5	-	27260156	A375	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.11116920459544524	[571]	[558,809,510,617]	-2	hSpCas9	negative selection	5874379
159203544	159203567	5	+	27260156	A375	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.0627445672154896	[1501]	[1693,2282,1489,1366]	-1	hSpCas9	negative selection	5874380
159203578	159203601	5	-	27260156	A375	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.3462023299574773	[350]	[326,427,341,218]	-5	hSpCas9	negative selection	5874381
159203449	159203472	5	+	27260156	COLO741	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.30979080509747225	[172]	[191,238,109]	-6	hSpCas9	negative selection	5931376
159203521	159203544	5	+	27260156	COLO741	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.333602848878497	[392]	[683,679,543]	7	hSpCas9	negative selection	5931377
159207766	159207789	5	+	27260156	COLO741	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.19064296840882666	[559]	[811,991,655]	4	hSpCas9	negative selection	5931378
159207762	159207785	5	-	27260156	COLO741	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.07802441620960915	[571]	[885,843,604]	1	hSpCas9	negative selection	5995630
159203544	159203567	5	+	27260156	COLO741	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.2963921016418234	[1501]	[1730,1675,1310]	-6	hSpCas9	negative selection	5995631
159203578	159203601	5	-	27260156	COLO741	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.11558370523406519	[350]	[582,356,321]	-2	hSpCas9	negative selection	5995632
159203449	159203472	5	+	27260156	CAL120	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.7040390847369253	[172]	[633,188,272]	9	hSpCas9	negative selection	6052627
159203521	159203544	5	+	27260156	CAL120	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.30681366700659424	[392]	[495,799,503]	4	hSpCas9	negative selection	6052628
159207766	159207789	5	+	27260156	CAL120	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.3934569616658986	[559]	[841,1109,784]	6	hSpCas9	negative selection	6052629
159207762	159207785	5	-	27260156	CAL120	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.2606581572709975	[571]	[658,710,424]	-4	hSpCas9	negative selection	6116881
159203544	159203567	5	+	27260156	CAL120	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.31779260088343975	[1501]	[1634,1640,1246]	-5	hSpCas9	negative selection	6116882
159203578	159203601	5	-	27260156	CAL120	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.5196376785111223	[350]	[334,308,274]	-6	hSpCas9	negative selection	6116883
159203449	159203472	5	+	27260156	CADOES1	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.4020389656048684	[172]	[139,89,133,122]	-6	hSpCas9	negative selection	6173878
159203521	159203544	5	+	27260156	CADOES1	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.11422761673079151	[392]	[260,428,392,503]	2	hSpCas9	negative selection	6173879
159207766	159207789	5	+	27260156	CADOES1	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.12479102949727405	[559]	[657,584,393,636]	2	hSpCas9	negative selection	6173880
159207762	159207785	5	-	27260156	CADOES1	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.03104084551923736	[571]	[650,536,594,384]	0	hSpCas9	negative selection	6238132
159203544	159203567	5	+	27260156	CADOES1	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.24192007714185704	[1501]	[1145,1262,1221,1090]	-4	hSpCas9	negative selection	6238133
159203578	159203601	5	-	27260156	CADOES1	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.575615171983745	[350]	[272,280,133,186]	-7	hSpCas9	negative selection	6238134
159203449	159203472	5	+	27260156	EWS502	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.2740230267843553	[172]	[297,224,221,123]	5	hSpCas9	negative selection	6295129
159203521	159203544	5	+	27260156	EWS502	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.19758031759852138	[392]	[435,552,506,408]	3	hSpCas9	negative selection	6295130
159207766	159207789	5	+	27260156	EWS502	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.11301738382532256	[559]	[552,560,598,880]	2	hSpCas9	negative selection	6295131
159207762	159207785	5	-	27260156	EWS502	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.04291876090169866	[571]	[538,511,820,640]	0	hSpCas9	negative selection	6359383
159203544	159203567	5	+	27260156	EWS502	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.20275956034601328	[1501]	[1231,1060,1696,1583]	-4	hSpCas9	negative selection	6359384
159203578	159203601	5	-	27260156	EWS502	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.31363218030938483	[350]	[227,373,266,333]	-5	hSpCas9	negative selection	6359385
159203449	159203472	5	+	27260156	EW8	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.2634630317863138	[172]	[307,189,117,80]	5	hSpCas9	negative selection	6416380
159203521	159203544	5	+	27260156	EW8	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.33443736880153024	[392]	[431,419,267,510]	6	hSpCas9	negative selection	6416381
159207766	159207789	5	+	27260156	EW8	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.016567713408795703	[559]	[476,567,433,362]	0	hSpCas9	negative selection	6416382
159207762	159207785	5	-	27260156	EW8	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.172771674629926	[571]	[707,397,525,475]	3	hSpCas9	negative selection	6480634
159203544	159203567	5	+	27260156	EW8	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.03729097530334946	[1501]	[1409,1263,970,1157]	0	hSpCas9	negative selection	6480635
159203578	159203601	5	-	27260156	EW8	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.12797308063446627	[350]	[275,328,210,234]	-2	hSpCas9	negative selection	6480636
159203449	159203472	5	+	27260156	CORL105	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.2663816614327752	[172]	[131,111,174,254]	-5	hSpCas9	negative selection	6537631
159203521	159203544	5	+	27260156	CORL105	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.5471593269224335	[392]	[682,599,769,652]	8	hSpCas9	negative selection	6537632
159207766	159207789	5	+	27260156	CORL105	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.059347780534867	[559]	[572,710,860,610]	1	hSpCas9	negative selection	6537633
159207762	159207785	5	-	27260156	CORL105	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.14986339138361465	[571]	[693,896,947,460]	3	hSpCas9	negative selection	6601885
159203544	159203567	5	+	27260156	CORL105	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.033708269378490696	[1501]	[1961,1812,1792,1635]	0	hSpCas9	negative selection	6601886
159203578	159203601	5	-	27260156	CORL105	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	0.07800040360687799	[350]	[452,413,515,365]	1	hSpCas9	negative selection	6601887
159203449	159203472	5	+	27260156	HS294T	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.13230498282755399	[172]	[45,37,101,59]	-2	hSpCas9	negative selection	6658882
159203521	159203544	5	+	27260156	HS294T	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.9533279145488558	[392]	[349,326,264,213]	9	hSpCas9	negative selection	6658883
159207766	159207789	5	+	27260156	HS294T	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.4357453875596534	[559]	[379,341,206,218]	6	hSpCas9	negative selection	6658884
159207762	159207785	5	-	27260156	HS294T	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.053832536862016916	[571]	[160,220,262,210]	0	hSpCas9	negative selection	6723136
159203544	159203567	5	+	27260156	HS294T	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.36141531857213915	[1501]	[883,552,606,967]	5	hSpCas9	negative selection	6723137
159203578	159203601	5	-	27260156	HS294T	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.29357883535404955	[350]	[103,102,137,95]	-4	hSpCas9	negative selection	6723138
159203449	159203472	5	+	27260156	HCC44	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.1325021570261702	[172]	[265,111,247,117]	-2	hSpCas9	negative selection	6780133
159203521	159203544	5	+	27260156	HCC44	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.5294042536649763	[392]	[606,635,794,549]	8	hSpCas9	negative selection	6780134
159207766	159207789	5	+	27260156	HCC44	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.338258990237832	[559]	[957,572,732,961]	5	hSpCas9	negative selection	6780135
159207762	159207785	5	-	27260156	HCC44	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.0938034101617195	[571]	[652,926,707,441]	1	hSpCas9	negative selection	6844387
159203544	159203567	5	+	27260156	HCC44	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.15567249588866217	[1501]	[1572,1201,1375,1946]	-3	hSpCas9	negative selection	6844388
159203578	159203601	5	-	27260156	HCC44	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	0.22520571557401264	[350]	[566,423,668,249]	3	hSpCas9	negative selection	6844389
159203449	159203472	5	+	27260156	G402	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.32160045616834054	[172]	[275,123,227,64]	-4	hSpCas9	negative selection	6901384
159203521	159203544	5	+	27260156	G402	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.6163093049771071	[392]	[471,1174,878,414]	7	hSpCas9	negative selection	6901385
159207766	159207789	5	+	27260156	G402	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	-0.02125400151148077	[559]	[856,502,900,456]	0	hSpCas9	negative selection	6901386
159207762	159207785	5	-	27260156	G402	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.07107263815524095	[571]	[612,716,1088,503]	0	hSpCas9	negative selection	6965638
159203544	159203567	5	+	27260156	G402	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.111884584000707	[1501]	[1725,1873,1177,1998]	-1	hSpCas9	negative selection	6965639
159203578	159203601	5	-	27260156	G402	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.30658306001966523	[350]	[484,560,270,110]	-4	hSpCas9	negative selection	6965640
159203449	159203472	5	+	27260156	L33	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.25359533184217065	[172]	[118,38,103,200]	-5	hSpCas9	negative selection	7022635
159203521	159203544	5	+	27260156	L33	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.8521653974009109	[392]	[580,349,463,667]	9	hSpCas9	negative selection	7022636
159207766	159207789	5	+	27260156	L33	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	-0.17769772013480556	[559]	[387,201,305,613]	-4	hSpCas9	negative selection	7022637
159207762	159207785	5	-	27260156	L33	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.1762110307710219	[571]	[564,181,321,501]	-4	hSpCas9	negative selection	7086889
159203544	159203567	5	+	27260156	L33	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.09553065287986273	[1501]	[1393,775,1064,1443]	2	hSpCas9	negative selection	7086890
159203578	159203601	5	-	27260156	L33	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.2198049441489382	[350]	[228,145,190,317]	-5	hSpCas9	negative selection	7086891
159203449	159203472	5	+	27260156	K562	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.09337626843152158	[172]	[400,64,114,24]	-1	hSpCas9	negative selection	7143886
159203521	159203544	5	+	27260156	K562	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.5802654366609838	[392]	[476,580,361,647]	7	hSpCas9	negative selection	7143887
159207766	159207789	5	+	27260156	K562	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.26395269974002344	[559]	[417,539,785,619]	3	hSpCas9	negative selection	7143888
159207762	159207785	5	-	27260156	K562	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.5289189063653366	[571]	[688,742,1112,415]	6	hSpCas9	negative selection	7208140
159203544	159203567	5	+	27260156	K562	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.2942202567933563	[1501]	[1270,1134,971,993]	-4	hSpCas9	negative selection	7208141
159203578	159203601	5	-	27260156	K562	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	0.3136723325188807	[350]	[221,293,799,230]	4	hSpCas9	negative selection	7208142
159203449	159203472	5	+	27260156	HT29	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.19837925957153324	[172]	[247,275,273,176]	4	hSpCas9	negative selection	7265137
159203521	159203544	5	+	27260156	HT29	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.33757134565064756	[392]	[623,670,575,552]	6	hSpCas9	negative selection	7265138
159207766	159207789	5	+	27260156	HT29	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.24748394689867337	[559]	[871,960,812,621]	5	hSpCas9	negative selection	7265139
159207762	159207785	5	-	27260156	HT29	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.1702274414421397	[571]	[841,761,912,628]	3	hSpCas9	negative selection	7329391
159203544	159203567	5	+	27260156	HT29	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.06244933822999266	[1501]	[1839,1963,1644,1578]	-1	hSpCas9	negative selection	7329392
159203578	159203601	5	-	27260156	HT29	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.05341032646347721	[350]	[436,518,429,282]	-1	hSpCas9	negative selection	7329393
159203449	159203472	5	+	27260156	MHHES1	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.05247214157637092	[172]	[202,156,152,223]	-1	hSpCas9	negative selection	7386388
159203521	159203544	5	+	27260156	MHHES1	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.7986633585453362	[392]	[754,1064,856,481]	9	hSpCas9	negative selection	7386389
159207766	159207789	5	+	27260156	MHHES1	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.0868152362606529	[559]	[590,766,788,546]	1	hSpCas9	negative selection	7386390
159207762	159207785	5	-	27260156	MHHES1	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.03937000150923686	[571]	[865,833,469,533]	0	hSpCas9	negative selection	7450642
159203544	159203567	5	+	27260156	MHHES1	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.2411102929556841	[1501]	[1450,1232,1423,1539]	-4	hSpCas9	negative selection	7450643
159203578	159203601	5	-	27260156	MHHES1	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.41996478540951593	[350]	[322,262,429,185]	-7	hSpCas9	negative selection	7450644
159203449	159203472	5	+	27260156	MEWO	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.21451792065722652	[172]	[208,119,102]	-5	hSpCas9	negative selection	7507639
159203521	159203544	5	+	27260156	MEWO	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.6085621016046558	[392]	[720,514,476]	9	hSpCas9	negative selection	7507640
159207766	159207789	5	+	27260156	MEWO	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.21132031824098352	[559]	[744,681,418]	4	hSpCas9	negative selection	7507641
159207762	159207785	5	-	27260156	MEWO	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.06504063756744716	[571]	[642,512,403]	-1	hSpCas9	negative selection	7571893
159203544	159203567	5	+	27260156	MEWO	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.18088865986553015	[1501]	[1616,973,1201]	-4	hSpCas9	negative selection	7571894
159203578	159203601	5	-	27260156	MEWO	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.010316755653920318	[350]	[362,369,251]	0	hSpCas9	negative selection	7571895
159203449	159203472	5	+	27260156	LNCAPCLONEFGC	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.26554403772203705	[172]	[110,135,147,128]	-4	hSpCas9	negative selection	7628890
159203521	159203544	5	+	27260156	LNCAPCLONEFGC	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.07359288025551866	[392]	[412,331,405,353]	1	hSpCas9	negative selection	7628891
159207766	159207789	5	+	27260156	LNCAPCLONEFGC	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.3147851896080244	[559]	[610,552,684,687]	5	hSpCas9	negative selection	7628892
159207762	159207785	5	-	27260156	LNCAPCLONEFGC	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.050253702648686976	[571]	[689,487,328,465]	-1	hSpCas9	negative selection	7693144
159203544	159203567	5	+	27260156	LNCAPCLONEFGC	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.12962154450276997	[1501]	[990,1243,1406,1360]	-2	hSpCas9	negative selection	7693145
159203578	159203601	5	-	27260156	LNCAPCLONEFGC	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.2339618329098801	[350]	[180,297,329,280]	-4	hSpCas9	negative selection	7693146
159203449	159203472	5	+	27260156	PANC0327	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.3332969982523868	[172]	[260,215,150,148]	5	hSpCas9	negative selection	7750141
159203521	159203544	5	+	27260156	PANC0327	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.4817199570458162	[392]	[625,503,424,403]	7	hSpCas9	negative selection	7750142
159207766	159207789	5	+	27260156	PANC0327	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.006075394359019104	[559]	[436,347,778,448]	0	hSpCas9	negative selection	7750143
159207762	159207785	5	-	27260156	PANC0327	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.23029171133772103	[571]	[664,423,677,644]	3	hSpCas9	negative selection	7814395
159203544	159203567	5	+	27260156	PANC0327	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.11152586738221948	[1501]	[1430,1386,1196,1755]	1	hSpCas9	negative selection	7814396
159203578	159203601	5	-	27260156	PANC0327	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.2983858586807359	[350]	[433,190,244,166]	-4	hSpCas9	negative selection	7814397
159203449	159203472	5	+	27260156	NCIH2009	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.5159930256860843	[172]	[150,126,225]	-6	hSpCas9	negative selection	7871392
159203521	159203544	5	+	27260156	NCIH2009	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	1.2684483084239604	[392]	[2088,1017,1015]	9	hSpCas9	negative selection	7871393
159207766	159207789	5	+	27260156	NCIH2009	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	-0.16066098127021014	[559]	[918,532,692]	-2	hSpCas9	negative selection	7871394
159207762	159207785	5	-	27260156	NCIH2009	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.07625698656995583	[571]	[973,853,723]	1	hSpCas9	negative selection	7935646
159203544	159203567	5	+	27260156	NCIH2009	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.007778770842666871	[1501]	[2220,1944,2184]	0	hSpCas9	negative selection	7935647
159203578	159203601	5	-	27260156	NCIH2009	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	0.19216505854050397	[350]	[436,642,573]	2	hSpCas9	negative selection	7935648
159203449	159203472	5	+	27260156	NCIH1373	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.19187503258595684	[172]	[168,196,262,65]	2	hSpCas9	negative selection	7992643
159203521	159203544	5	+	27260156	NCIH1373	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.4965018743630524	[392]	[1051,608,388,130]	5	hSpCas9	negative selection	7992644
159207766	159207789	5	+	27260156	NCIH1373	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.1580363508303006	[559]	[647,454,785,246]	1	hSpCas9	negative selection	7992645
159207762	159207785	5	-	27260156	NCIH1373	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.05087557491033745	[571]	[1033,495,745,114]	0	hSpCas9	negative selection	8056897
159203544	159203567	5	+	27260156	NCIH1373	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.2894405642533182	[1501]	[1672,1596,1648,887]	3	hSpCas9	negative selection	8056898
159203578	159203601	5	-	27260156	NCIH1373	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.9439030420731325	[350]	[119,138,178,100]	-7	hSpCas9	negative selection	8056899
159203449	159203472	5	+	27260156	PATU8902	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.15209779363816267	[172]	[286,274,202,87]	-1	hSpCas9	negative selection	8113894
159203521	159203544	5	+	27260156	PATU8902	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.5158340815602214	[392]	[855,986,457,923]	5	hSpCas9	negative selection	8113895
159207766	159207789	5	+	27260156	PATU8902	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.19168626769088903	[559]	[836,1152,700,918]	2	hSpCas9	negative selection	8113896
159207762	159207785	5	-	27260156	PATU8902	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.26111872554388255	[571]	[1036,734,1136,838]	2	hSpCas9	negative selection	8178148
159203544	159203567	5	+	27260156	PATU8902	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.6950689451349586	[1501]	[1660,966,1024,1605]	-6	hSpCas9	negative selection	8178149
159203578	159203601	5	-	27260156	PATU8902	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.3864039614392127	[350]	[466,525,274,232]	-4	hSpCas9	negative selection	8178150
159203449	159203472	5	+	27260156	PANC1	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.0253327229310214	[172]	[199,160,177,76]	0	hSpCas9	negative selection	8235145
159203521	159203544	5	+	27260156	PANC1	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	-0.15737530332345817	[392]	[269,448,242,277]	-3	hSpCas9	negative selection	8235146
159207766	159207789	5	+	27260156	PANC1	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.2834158610211224	[559]	[650,665,524,515]	4	hSpCas9	negative selection	8235147
159207762	159207785	5	-	27260156	PANC1	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.23190748574521441	[571]	[579,807,491,480]	3	hSpCas9	negative selection	8299399
159203544	159203567	5	+	27260156	PANC1	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.272687958002404	[1501]	[977,1436,1047,896]	-4	hSpCas9	negative selection	8299400
159203578	159203601	5	-	27260156	PANC1	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.6777796372639859	[350]	[105,328,189,160]	-7	hSpCas9	negative selection	8299401
159203449	159203472	5	+	27260156	PANC0813	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.5581894017766196	[172]	[134,141,195,81]	-7	hSpCas9	negative selection	8356396
159203521	159203544	5	+	27260156	PANC0813	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.868798255446338	[392]	[886,669,881,930]	9	hSpCas9	negative selection	8356397
159207766	159207789	5	+	27260156	PANC0813	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.137017930034522	[559]	[706,670,789,722]	2	hSpCas9	negative selection	8356398
159207762	159207785	5	-	27260156	PANC0813	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.05291566026598715	[571]	[698,839,660,407]	-1	hSpCas9	negative selection	8420650
159203544	159203567	5	+	27260156	PANC0813	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.10191843906401443	[1501]	[1814,1678,1449,1643]	-2	hSpCas9	negative selection	8420651
159203578	159203601	5	-	27260156	PANC0813	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.47036563299129125	[350]	[312,283,325,269]	-6	hSpCas9	negative selection	8420652
159203449	159203472	5	+	27260156	RDES	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.19937767216932278	[172]	[147,186,161,197]	-3	hSpCas9	negative selection	8477647
159203521	159203544	5	+	27260156	RDES	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.46961862909431096	[392]	[390,503,890,800]	7	hSpCas9	negative selection	8477648
159207766	159207789	5	+	27260156	RDES	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.2988091522640771	[559]	[618,792,777,1027]	5	hSpCas9	negative selection	8477649
159207762	159207785	5	-	27260156	RDES	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.10742915455709101	[571]	[628,538,669,1060]	1	hSpCas9	negative selection	8541901
159203544	159203567	5	+	27260156	RDES	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.077981267146771	[1501]	[1350,1412,1687,2218]	-1	hSpCas9	negative selection	8541902
159203578	159203601	5	-	27260156	RDES	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.2942443942934136	[350]	[313,210,416,391]	-5	hSpCas9	negative selection	8541903
159203449	159203472	5	+	27260156	PC3	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.025302026332351568	[172]	[63,194,503,100]	0	hSpCas9	negative selection	8598898
159203521	159203544	5	+	27260156	PC3	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.46867286278636444	[392]	[471,364,826,587]	8	hSpCas9	negative selection	8598899
159207766	159207789	5	+	27260156	PC3	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.36073672395476786	[559]	[418,593,1556,696]	7	hSpCas9	negative selection	8598900
159207762	159207785	5	-	27260156	PC3	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.4072848328911547	[571]	[374,301,693,426]	-7	hSpCas9	negative selection	8663152
159203544	159203567	5	+	27260156	PC3	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.018139043060990456	[1501]	[1234,1412,2353,1161]	0	hSpCas9	negative selection	8663153
159203578	159203601	5	-	27260156	PC3	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	0.05951569672629964	[350]	[163,485,676,303]	1	hSpCas9	negative selection	8663154
159203449	159203472	5	+	27260156	PATU8988T	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.08105413632470215	[172]	[139,169,297,89]	1	hSpCas9	negative selection	8720149
159203521	159203544	5	+	27260156	PATU8988T	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.6006997586074825	[392]	[561,749,293,729]	8	hSpCas9	negative selection	8720150
159207766	159207789	5	+	27260156	PATU8988T	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.5344857465202529	[559]	[578,1202,528,873]	8	hSpCas9	negative selection	8720151
159207762	159207785	5	-	27260156	PATU8988T	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.23964919969374038	[571]	[962,693,435,512]	4	hSpCas9	negative selection	8784403
159203544	159203567	5	+	27260156	PATU8988T	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	0.108241680547837	[1501]	[1509,1532,1171,2086]	1	hSpCas9	negative selection	8784404
159203578	159203601	5	-	27260156	PATU8988T	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	0.733702955855745	[350]	[485,638,698,425]	9	hSpCas9	negative selection	8784405
159203449	159203472	5	+	27260156	T47D	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.02969947412734575	[172]	[175,163,222,264]	0	hSpCas9	negative selection	8841400
159203521	159203544	5	+	27260156	T47D	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.12407525465612154	[392]	[491,400,496,617]	2	hSpCas9	negative selection	8841401
159207766	159207789	5	+	27260156	T47D	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.0645116759585419	[559]	[669,622,667,775]	1	hSpCas9	negative selection	8841402
159207762	159207785	5	-	27260156	T47D	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.01712387532240245	[571]	[634,570,703,732]	0	hSpCas9	negative selection	8905654
159203544	159203567	5	+	27260156	T47D	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.19299867502911172	[1501]	[1558,1291,1628,1665]	-4	hSpCas9	negative selection	8905655
159203578	159203601	5	-	27260156	T47D	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	0.034036160947744865	[350]	[390,358,411,520]	0	hSpCas9	negative selection	8905656
159203449	159203472	5	+	27260156	SU8686	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.2684917399609221	[172]	[106,117,238,108]	-4	hSpCas9	negative selection	8962651
159203521	159203544	5	+	27260156	SU8686	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.835637363784858	[392]	[652,502,766,921]	9	hSpCas9	negative selection	8962652
159207766	159207789	5	+	27260156	SU8686	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.27094353199759813	[559]	[539,525,793,886]	4	hSpCas9	negative selection	8962653
159207762	159207785	5	-	27260156	SU8686	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.08624265333486364	[571]	[502,490,653,817]	1	hSpCas9	negative selection	9026905
159203544	159203567	5	+	27260156	SU8686	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.22383357266675508	[1501]	[1099,1154,1268,1665]	-4	hSpCas9	negative selection	9026906
159203578	159203601	5	-	27260156	SU8686	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.2309586492665196	[350]	[239,261,309,399]	-4	hSpCas9	negative selection	9026907
159203449	159203472	5	+	27260156	SKES1	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.47696812388983245	[172]	[117,197,109,81]	-8	hSpCas9	negative selection	9083902
159203521	159203544	5	+	27260156	SKES1	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.5700254281999395	[392]	[692,730,443,498]	9	hSpCas9	negative selection	9083903
159207766	159207789	5	+	27260156	SKES1	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.3272300889779527	[559]	[743,738,607,714]	6	hSpCas9	negative selection	9083904
159207762	159207785	5	-	27260156	SKES1	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.026912963925303846	[571]	[655,534,583,478]	0	hSpCas9	negative selection	9148156
159203544	159203567	5	+	27260156	SKES1	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.2555390559373518	[1501]	[1467,1502,1065,1055]	-5	hSpCas9	negative selection	9148157
159203578	159203601	5	-	27260156	SKES1	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.40338427376821445	[350]	[300,290,290,189]	-7	hSpCas9	negative selection	9148158
159203449	159203472	5	+	27260156	TOV112D	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.43425375022349977	[172]	[108,131,141,128]	-7	hSpCas9	negative selection	9205153
159203521	159203544	5	+	27260156	TOV112D	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.014889126703914901	[392]	[308,513,525,265]	0	hSpCas9	negative selection	9205154
159207766	159207789	5	+	27260156	TOV112D	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.007580587814724704	[559]	[598,784,517,413]	0	hSpCas9	negative selection	9205155
159207762	159207785	5	-	27260156	TOV112D	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.26714296072017363	[571]	[356,487,454,592]	-5	hSpCas9	negative selection	9269407
159203544	159203567	5	+	27260156	TOV112D	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.2221513037844256	[1501]	[1650,1188,1536,798]	-4	hSpCas9	negative selection	9269408
159203578	159203601	5	-	27260156	TOV112D	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.07853978157323649	[350]	[416,384,287,262]	-1	hSpCas9	negative selection	9269409
159203449	159203472	5	+	27260156	TC71	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	-0.18064292863417064	[172]	[140,153,134,229]	-5	hSpCas9	negative selection	9326404
159203521	159203544	5	+	27260156	TC71	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.4083139570119445	[392]	[550,532,605,543]	8	hSpCas9	negative selection	9326405
159207766	159207789	5	+	27260156	TC71	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	0.10385030086130348	[559]	[521,661,656,747]	2	hSpCas9	negative selection	9326406
159207762	159207785	5	-	27260156	TC71	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	0.016978094871714422	[571]	[524,655,637,666]	0	hSpCas9	negative selection	9390658
159203544	159203567	5	+	27260156	TC71	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.20594553046872788	[1501]	[1424,1294,1299,1576]	-5	hSpCas9	negative selection	9390659
159203578	159203601	5	-	27260156	TC71	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.010656198006356088	[350]	[320,344,377,455]	0	hSpCas9	negative selection	9390660
159203449	159203472	5	+	27260156	TC32	viability	TAAGAGCCAAATACTTATACTGG	RNF145	ENSG00000145860	0.2928667995580063	[172]	[140,160,188,320]	5	hSpCas9	negative selection	9447655
159203521	159203544	5	+	27260156	TC32	viability	AGCTGACATCCCATCTGTACAGG	RNF145	ENSG00000145860	0.47335192880864563	[392]	[422,588,592,400]	7	hSpCas9	negative selection	9447656
159207766	159207789	5	+	27260156	TC32	viability	ATAAACTACTAGCAATTCTGTGG	RNF145	ENSG00000145860	-0.026498416060973917	[559]	[549,355,585,617]	0	hSpCas9	negative selection	9447657
159207762	159207785	5	-	27260156	TC32	viability	AGAATTGCTAGTAGTTTATGTGG	RNF145	ENSG00000145860	-0.04547208640445438	[571]	[493,385,666,588]	-1	hSpCas9	negative selection	9511909
159203544	159203567	5	+	27260156	TC32	viability	ACATCCAACAGCATGATGCTTGG	RNF145	ENSG00000145860	-0.21134278840080833	[1501]	[1139,980,1382,1438]	-4	hSpCas9	negative selection	9511910
159203578	159203601	5	-	27260156	TC32	viability	ACTGGAGGCAGTGTTAAATGTGG	RNF145	ENSG00000145860	-0.3593975900829665	[350]	[267,254,169,304]	-6	hSpCas9	negative selection	9511911
159158741	159158764	5	-	27869803	HPAFII	viability after 27 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.8874131577302631	[883]	[1228,551,NaN]	7	hSpCas9	negative selection	9590926
159161472	159161495	5	+	27869803	HPAFII	viability after 27 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.6806529727104058	[1097]	[1197,697,NaN]	5	hSpCas9	negative selection	9590927
159203531	159203554	5	-	27869803	HPAFII	viability after 27 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.9353578049674227	[369]	[473,286,NaN]	7	hSpCas9	negative selection	9590928
159209889	159209912	5	-	27869803	HPAFII	viability after 27 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	-0.1484118928292865	[325]	[248,75,NaN]	-1	hSpCas9	negative selection	9590929
159209894	159209917	5	-	27869803	HPAFII	viability after 27 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-1.2543171887326847	[98]	[17,24,NaN]	-7	hSpCas9	negative selection	9590930
159158741	159158764	5	-	27869803	HPAFII	viability after 15 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.4188884649144269	[883]	[1977,829,NaN]	5	hSpCas9	negative selection	9673375
159161472	159161495	5	+	27869803	HPAFII	viability after 15 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.5112495946626807	[1097]	[1803,1605,NaN]	6	hSpCas9	negative selection	9673376
159203531	159203554	5	-	27869803	HPAFII	viability after 15 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.7810576211314724	[369]	[871,565,NaN]	8	hSpCas9	negative selection	9673377
159209889	159209912	5	-	27869803	HPAFII	viability after 15 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.25417487785376847	[325]	[526,349,NaN]	3	hSpCas9	negative selection	9673378
159209894	159209917	5	-	27869803	HPAFII	viability after 15 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-1.791521153201592	[98]	[47,19,NaN]	-9	hSpCas9	negative selection	9673379
159158741	159158764	5	-	27869803	ASPC1	viability after 36 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.7297493060114031	[1937]	[1660,962,857]	7	hSpCas9	negative selection	9755824
159161472	159161495	5	+	27869803	ASPC1	viability after 36 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.41262713272873874	[2814]	[1365,1964,731]	4	hSpCas9	negative selection	9755825
159203531	159203554	5	-	27869803	ASPC1	viability after 36 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.7593382252263272	[846]	[354,360,707]	7	hSpCas9	negative selection	9755826
159209889	159209912	5	-	27869803	ASPC1	viability after 36 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	-0.2914903729818539	[669]	[452,57,110]	-3	hSpCas9	negative selection	9755827
159209894	159209917	5	-	27869803	ASPC1	viability after 36 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	0.8180836299470357	[188]	[178,152,41]	7	hSpCas9	negative selection	9755828
159158741	159158764	5	-	27869803	PATU8988S	viability after 35 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.5418424068993615	[1710]	[1099,905,NaN]	6	hSpCas9	negative selection	9838273
159161472	159161495	5	+	27869803	PATU8988S	viability after 35 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.03518813315665348	[2748]	[1351,915,NaN]	0	hSpCas9	negative selection	9838274
159203531	159203554	5	-	27869803	PATU8988S	viability after 35 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.6046487535304598	[832]	[356,663,NaN]	6	hSpCas9	negative selection	9838275
159209889	159209912	5	-	27869803	PATU8988S	viability after 35 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.05524304940091468	[631]	[252,275,NaN]	0	hSpCas9	negative selection	9838276
159209894	159209917	5	-	27869803	PATU8988S	viability after 35 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	0.11473152900522843	[155]	[80,54,NaN]	1	hSpCas9	negative selection	9838277
159158741	159158764	5	-	27869803	PATU8988S	viability after 31 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.2856929457120121	[1710]	[733,955,NaN]	3	hSpCas9	negative selection	9920722
159161472	159161495	5	+	27869803	PATU8988S	viability after 31 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	-0.06017599307245103	[2748]	[1075,1019,NaN]	0	hSpCas9	negative selection	9920723
159203531	159203554	5	-	27869803	PATU8988S	viability after 31 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	0.4723425276296115	[832]	[345,606,NaN]	6	hSpCas9	negative selection	9920724
159209889	159209912	5	-	27869803	PATU8988S	viability after 31 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.40149490138200644	[631]	[276,403,NaN]	5	hSpCas9	negative selection	9920725
159209894	159209917	5	-	27869803	PATU8988S	viability after 31 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-0.021616260168379142	[155]	[55,67,NaN]	0	hSpCas9	negative selection	9920726
159158741	159158764	5	-	27869803	HPAFII	viability after 35 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	1.1271593032839107	[883]	[1183,744,NaN]	7	hSpCas9	negative selection	10003171
159161472	159161495	5	+	27869803	HPAFII	viability after 35 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.9111335530864175	[1097]	[1303,753,NaN]	6	hSpCas9	negative selection	10003172
159203531	159203554	5	-	27869803	HPAFII	viability after 35 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	1.1117246762437587	[369]	[329,488,NaN]	7	hSpCas9	negative selection	10003173
159209889	159209912	5	-	27869803	HPAFII	viability after 35 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	0.1289152706447393	[325]	[163,198,NaN]	0	hSpCas9	negative selection	10003174
159209894	159209917	5	-	27869803	HPAFII	viability after 35 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-1.8707895205744112	[98]	[8,18,NaN]	-7	hSpCas9	negative selection	10003175
159158741	159158764	5	-	27869803	HPAFII	viability after 31 days	TGCCAGACGACCAGATAACCAGG	RNF145	ENSG00000145860	0.663801699021429	[883]	[1097,445,NaN]	5	hSpCas9	negative selection	10085620
159161472	159161495	5	+	27869803	HPAFII	viability after 31 days	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.5966849102773719	[1097]	[1006,849,NaN]	4	hSpCas9	negative selection	10085621
159203531	159203554	5	-	27869803	HPAFII	viability after 31 days	TGTTGGATGTCCTGTACAGATGG	RNF145	ENSG00000145860	1.3273073032797376	[369]	[421,628,NaN]	8	hSpCas9	negative selection	10085622
159209889	159209912	5	-	27869803	HPAFII	viability after 31 days	TACTGCGAATGCACCGGGACAGG	RNF145	ENSG00000145860	-0.2277105282871834	[325]	[183,125,NaN]	-1	hSpCas9	negative selection	10085623
159209894	159209917	5	-	27869803	HPAFII	viability after 31 days	ATTGCTACTGCGAATGCACCGGG	RNF145	ENSG00000145860	-1.0525935570787126	[98]	[21,31,NaN]	-6	hSpCas9	negative selection	10085624
159161559	159161582	5	-	28162770	P31FUJ	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	-0.4099587750877669	[224]	[198]	-4	hSpCas9	negative selection	10226175
159174098	159174121	5	+	28162770	P31FUJ	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	0.25716378237103077	[135]	[190]	2	hSpCas9	negative selection	10226176
159203593	159203616	5	-	28162770	P31FUJ	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	-4.960722658977577	[52]	[1]	-9	hSpCas9	negative selection	10226177
159162920	159162943	5	+	28162770	P31FUJ	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	0.7524762898788557	[196]	[389]	8	hSpCas9	negative selection	10226178
159161493	159161516	5	+	28162770	P31FUJ	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	-0.5440038927086828	[66]	[53]	-4	hSpCas9	negative selection	10226179
159161352	159161375	5	-	28162770	P31FUJ	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-1.9967348461808538	[359]	[105]	-8	hSpCas9	negative selection	10226180
159203569	159203592	5	-	28162770	P31FUJ	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	-0.10247033606669853	[549]	[601]	-1	hSpCas9	negative selection	10226181
159203548	159203571	5	-	28162770	P31FUJ	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.3760592553946109	[200]	[181]	-3	hSpCas9	negative selection	10226182
159174119	159174142	5	+	28162770	P31FUJ	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	0.4906801603882054	[42]	[70]	5	hSpCas9	negative selection	10226183
159161472	159161495	5	+	28162770	P31FUJ	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.22031564029071649	[457]	[626]	2	hSpCas9	negative selection	10226184
159161559	159161582	5	-	28162770	TF1	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10395541
159174098	159174121	5	+	28162770	TF1	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10395542
159203593	159203616	5	-	28162770	TF1	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	NaN	[NaN]	[49]	1	hSpCas9	negative selection	10395543
159162920	159162943	5	+	28162770	TF1	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	NaN	[NaN]	[247]	1	hSpCas9	negative selection	10395544
159161493	159161516	5	+	28162770	TF1	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10395545
159161352	159161375	5	-	28162770	TF1	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	NaN	[NaN]	[182]	1	hSpCas9	negative selection	10395546
159203569	159203592	5	-	28162770	TF1	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	NaN	[NaN]	[552]	1	hSpCas9	negative selection	10395547
159203548	159203571	5	-	28162770	TF1	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10395548
159174119	159174142	5	+	28162770	TF1	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10395549
159161472	159161495	5	+	28162770	TF1	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	NaN	[NaN]	[522]	1	hSpCas9	negative selection	10395550
159161559	159161582	5	-	28162770	SKM1	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	1.2014572748019836	[60]	[247]	9	hSpCas9	negative selection	10564907
159174098	159174121	5	+	28162770	SKM1	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	0.970556222107518	[27]	[96]	8	hSpCas9	negative selection	10564908
159203593	159203616	5	-	28162770	SKM1	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	0.3300013954230443	[8]	[19]	3	hSpCas9	negative selection	10564909
159162920	159162943	5	+	28162770	SKM1	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	0.2898911820488917	[61]	[133]	3	hSpCas9	negative selection	10564910
159161493	159161516	5	+	28162770	SKM1	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	0.6804986425071778	[23]	[67]	6	hSpCas9	negative selection	10564911
159161352	159161375	5	-	28162770	SKM1	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-0.3365748708517637	[84]	[118]	-3	hSpCas9	negative selection	10564912
159203569	159203592	5	-	28162770	SKM1	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	0.7056750620819332	[136]	[394]	6	hSpCas9	negative selection	10564913
159203548	159203571	5	-	28162770	SKM1	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.5071283606685936	[40]	[50]	-4	hSpCas9	negative selection	10564914
159174119	159174142	5	+	28162770	SKM1	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	-1.0443941193584534	[13]	[11]	-6	hSpCas9	negative selection	10564915
159161472	159161495	5	+	28162770	SKM1	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	1.1048318894160227	[90]	[345]	8	hSpCas9	negative selection	10564916
159161559	159161582	5	-	28162770	SKM1	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	1.2014572748019836	[60]	[247]	9	hSpCas9	negative selection	10734273
159174098	159174121	5	+	28162770	SKM1	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	0.970556222107518	[27]	[96]	8	hSpCas9	negative selection	10734274
159203593	159203616	5	-	28162770	SKM1	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	0.3300013954230443	[8]	[19]	3	hSpCas9	negative selection	10734275
159162920	159162943	5	+	28162770	SKM1	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	0.2898911820488917	[61]	[133]	3	hSpCas9	negative selection	10734276
159161493	159161516	5	+	28162770	SKM1	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	0.6804986425071778	[23]	[67]	6	hSpCas9	negative selection	10734277
159161352	159161375	5	-	28162770	SKM1	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-0.3365748708517637	[84]	[118]	-3	hSpCas9	negative selection	10734278
159203569	159203592	5	-	28162770	SKM1	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	0.7056750620819332	[136]	[394]	6	hSpCas9	negative selection	10734279
159203548	159203571	5	-	28162770	SKM1	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.5071283606685936	[40]	[50]	-4	hSpCas9	negative selection	10734280
159174119	159174142	5	+	28162770	SKM1	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	-1.0443941193584534	[13]	[11]	-6	hSpCas9	negative selection	10734281
159161472	159161495	5	+	28162770	SKM1	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	1.1048318894160227	[90]	[345]	8	hSpCas9	negative selection	10734282
159161559	159161582	5	-	28162770	PL21	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	-0.4142066930129302	[247]	[80]	-3	hSpCas9	negative selection	10903639
159174098	159174121	5	+	28162770	PL21	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	0.2423678498786177	[100]	[51]	2	hSpCas9	negative selection	10903640
159203593	159203616	5	-	28162770	PL21	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	-0.47228572748217545	[50]	[15]	-3	hSpCas9	negative selection	10903641
159162920	159162943	5	+	28162770	PL21	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	1.2001396144893202	[186]	[186]	8	hSpCas9	negative selection	10903642
159161493	159161516	5	+	28162770	PL21	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	0.4916024286496312	[66]	[40]	4	hSpCas9	negative selection	10903643
159161352	159161375	5	-	28162770	PL21	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-0.6175869916407224	[348]	[98]	-4	hSpCas9	negative selection	10903644
159203569	159203592	5	-	28162770	PL21	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	0.7666960001132201	[446]	[330]	6	hSpCas9	negative selection	10903645
159203548	159203571	5	-	28162770	PL21	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.7384598408465366	[91]	[23]	-5	hSpCas9	negative selection	10903646
159174119	159174142	5	+	28162770	PL21	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	0.837569535104612	[53]	[41]	7	hSpCas9	negative selection	10903647
159161472	159161495	5	+	28162770	PL21	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.4793842475043729	[294]	[178]	4	hSpCas9	negative selection	10903648
159161559	159161582	5	-	28162770	P31FUJ	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	-0.4099587750877669	[224]	[198]	-4	hSpCas9	negative selection	11073005
159174098	159174121	5	+	28162770	P31FUJ	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	0.25716378237103077	[135]	[190]	2	hSpCas9	negative selection	11073006
159203593	159203616	5	-	28162770	P31FUJ	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	-4.960722658977577	[52]	[1]	-9	hSpCas9	negative selection	11073007
159162920	159162943	5	+	28162770	P31FUJ	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	0.7524762898788557	[196]	[389]	8	hSpCas9	negative selection	11073008
159161493	159161516	5	+	28162770	P31FUJ	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	-0.5440038927086828	[66]	[53]	-4	hSpCas9	negative selection	11073009
159161352	159161375	5	-	28162770	P31FUJ	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-1.9967348461808538	[359]	[105]	-8	hSpCas9	negative selection	11073010
159203569	159203592	5	-	28162770	P31FUJ	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	-0.10247033606669853	[549]	[601]	-1	hSpCas9	negative selection	11073011
159203548	159203571	5	-	28162770	P31FUJ	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.3760592553946109	[200]	[181]	-3	hSpCas9	negative selection	11073012
159174119	159174142	5	+	28162770	P31FUJ	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	0.4906801603882054	[42]	[70]	5	hSpCas9	negative selection	11073013
159161472	159161495	5	+	28162770	P31FUJ	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.22031564029071649	[457]	[626]	2	hSpCas9	negative selection	11073014
159161559	159161582	5	-	28162770	OCIAML5	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	0.9255410077995551	[83]	[287]	7	hSpCas9	negative selection	11242371
159174098	159174121	5	+	28162770	OCIAML5	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	0.36819954936406296	[96]	[225]	3	hSpCas9	negative selection	11242372
159203593	159203616	5	-	28162770	OCIAML5	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	-3.267104070142841	[63]	[11]	-9	hSpCas9	negative selection	11242373
159162920	159162943	5	+	28162770	OCIAML5	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	0.37925897524245866	[137]	[323]	3	hSpCas9	negative selection	11242374
159161493	159161516	5	+	28162770	OCIAML5	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	0.12590712280600425	[32]	[64]	1	hSpCas9	negative selection	11242375
159161352	159161375	5	-	28162770	OCIAML5	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-0.6870073245935007	[197]	[221]	-4	hSpCas9	negative selection	11242376
159203569	159203592	5	-	28162770	OCIAML5	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	0.20266616181442898	[374]	[778]	1	hSpCas9	negative selection	11242377
159203548	159203571	5	-	28162770	OCIAML5	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.21463665024870515	[80]	[125]	-1	hSpCas9	negative selection	11242378
159174119	159174142	5	+	28162770	OCIAML5	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	-0.8047608560856404	[59]	[61]	-5	hSpCas9	negative selection	11242379
159161472	159161495	5	+	28162770	OCIAML5	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	-1.7300760464853866	[203]	[110]	-7	hSpCas9	negative selection	11242380
159161559	159161582	5	-	28162770	EOL1	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	-0.40947846583469794	[478]	[189]	-3	hSpCas9	negative selection	11411737
159174098	159174121	5	+	28162770	EOL1	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	-0.8075190231828324	[195]	[58]	-5	hSpCas9	negative selection	11411738
159203593	159203616	5	-	28162770	EOL1	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	-1.2523299905135445	[103]	[22]	-7	hSpCas9	negative selection	11411739
159162920	159162943	5	+	28162770	EOL1	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	-0.8401207513855193	[332]	[97]	-5	hSpCas9	negative selection	11411740
159161493	159161516	5	+	28162770	EOL1	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	-0.6831348056507052	[127]	[41]	-5	hSpCas9	negative selection	11411741
159161352	159161375	5	-	28162770	EOL1	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-1.353697884499431	[552]	[113]	-7	hSpCas9	negative selection	11411742
159203569	159203592	5	-	28162770	EOL1	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	0.6317660223426889	[636]	[519]	5	hSpCas9	negative selection	11411743
159203548	159203571	5	-	28162770	EOL1	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.8624585050952672	[175]	[50]	-6	hSpCas9	negative selection	11411744
159174119	159174142	5	+	28162770	EOL1	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	0.1540296176933018	[57]	[33]	1	hSpCas9	negative selection	11411745
159161472	159161495	5	+	28162770	EOL1	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.5056579467960841	[499]	[373]	4	hSpCas9	negative selection	11411746
159161559	159161582	5	-	28162770	MOLM13	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	0.9590475141415689	[322]	[453]	7	hSpCas9	negative selection	11581103
159174098	159174121	5	+	28162770	MOLM13	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	-1.4845822483728355	[208]	[53]	-6	hSpCas9	negative selection	11581104
159203593	159203616	5	-	28162770	MOLM13	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	-0.2805718514594566	[83]	[49]	-2	hSpCas9	negative selection	11581105
159162920	159162943	5	+	28162770	MOLM13	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	-0.1628768087897021	[335]	[216]	-1	hSpCas9	negative selection	11581106
159161493	159161516	5	+	28162770	MOLM13	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	-0.4166334010354855	[95]	[51]	-2	hSpCas9	negative selection	11581107
159161352	159161375	5	-	28162770	MOLM13	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-2.1561078323606604	[486]	[78]	-7	hSpCas9	negative selection	11581108
159203569	159203592	5	-	28162770	MOLM13	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	-1.093989506063536	[681]	[230]	-5	hSpCas9	negative selection	11581109
159203548	159203571	5	-	28162770	MOLM13	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.039070607175304306	[188]	[132]	0	hSpCas9	negative selection	11581110
159174119	159174142	5	+	28162770	MOLM13	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	-0.639025822371933	[55]	[25]	-4	hSpCas9	negative selection	11581111
159161472	159161495	5	+	28162770	MOLM13	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	-0.5182250922004714	[516]	[260]	-3	hSpCas9	negative selection	11581112
159161559	159161582	5	-	28162770	HEL	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	0.1260962898831347	[298]	[208]	1	hSpCas9	negative selection	11750469
159174098	159174121	5	+	28162770	HEL	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	-0.24900827734761954	[153]	[82]	-2	hSpCas9	negative selection	11750470
159203593	159203616	5	-	28162770	HEL	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	-2.6584307027202083	[68]	[6]	-8	hSpCas9	negative selection	11750471
159162920	159162943	5	+	28162770	HEL	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	0.18330721336305952	[274]	[199]	1	hSpCas9	negative selection	11750472
159161493	159161516	5	+	28162770	HEL	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	-1.5347993535518307	[94]	[20]	-7	hSpCas9	negative selection	11750473
159161352	159161375	5	-	28162770	HEL	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-0.7415680480386921	[448]	[171]	-5	hSpCas9	negative selection	11750474
159203569	159203592	5	-	28162770	HEL	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	-0.47988045466359874	[539]	[247]	-3	hSpCas9	negative selection	11750475
159203548	159203571	5	-	28162770	HEL	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	0.16357099530179753	[137]	[98]	1	hSpCas9	negative selection	11750476
159174119	159174142	5	+	28162770	HEL	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	0.10840240434916915	[41]	[28]	0	hSpCas9	negative selection	11750477
159161472	159161495	5	+	28162770	HEL	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.01777826334728172	[383]	[248]	0	hSpCas9	negative selection	11750478
159161559	159161582	5	-	28162770	MV411	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	-1.018296004651974	[213]	[88]	-6	hSpCas9	negative selection	11919835
159174098	159174121	5	+	28162770	MV411	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	-0.905641779221614	[148]	[66]	-6	hSpCas9	negative selection	11919836
159203593	159203616	5	-	28162770	MV411	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	0.7746845536476441	[33]	[48]	7	hSpCas9	negative selection	11919837
159162920	159162943	5	+	28162770	MV411	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	-0.618545101245537	[225]	[123]	-4	hSpCas9	negative selection	11919838
159161493	159161516	5	+	28162770	MV411	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	0.02504512944632742	[27]	[23]	0	hSpCas9	negative selection	11919839
159161352	159161375	5	-	28162770	MV411	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-1.4518576254173756	[314]	[96]	-7	hSpCas9	negative selection	11919840
159203569	159203592	5	-	28162770	MV411	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	0.34677732576038456	[490]	[525]	3	hSpCas9	negative selection	11919841
159203548	159203571	5	-	28162770	MV411	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.9452075271596208	[111]	[48]	-6	hSpCas9	negative selection	11919842
159174119	159174142	5	+	28162770	MV411	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	0.29050627267466167	[32]	[33]	2	hSpCas9	negative selection	11919843
159161472	159161495	5	+	28162770	MV411	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.03984213137440784	[290]	[251]	0	hSpCas9	negative selection	11919844
159161559	159161582	5	-	28162770	MONOMAC1	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	0.6065659401369428	[164]	[287]	6	hSpCas9	negative selection	12089201
159174098	159174121	5	+	28162770	MONOMAC1	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	0.36906662641028665	[76]	[113]	3	hSpCas9	negative selection	12089202
159203593	159203616	5	-	28162770	MONOMAC1	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	-0.4085409522532655	[43]	[37]	-4	hSpCas9	negative selection	12089203
159162920	159162943	5	+	28162770	MONOMAC1	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	-0.9615487681114225	[140]	[82]	-6	hSpCas9	negative selection	12089204
159161493	159161516	5	+	28162770	MONOMAC1	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	1.1248912478278086	[39]	[99]	8	hSpCas9	negative selection	12089205
159161352	159161375	5	-	28162770	MONOMAC1	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	0.45214809661592914	[226]	[355]	4	hSpCas9	negative selection	12089206
159203569	159203592	5	-	28162770	MONOMAC1	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	0.1086281235034543	[338]	[418]	1	hSpCas9	negative selection	12089207
159203548	159203571	5	-	28162770	MONOMAC1	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	1.2724484362416664	[51]	[143]	9	hSpCas9	negative selection	12089208
159174119	159174142	5	+	28162770	MONOMAC1	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	0.7289625714966697	[19]	[37]	7	hSpCas9	negative selection	12089209
159161472	159161495	5	+	28162770	MONOMAC1	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.24700052394184258	[196]	[267]	2	hSpCas9	negative selection	12089210
159161559	159161582	5	-	28162770	OCIAML2	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	0.28171099481096074	[41]	[282]	2	hSpCas9	negative selection	12258567
159174098	159174121	5	+	28162770	OCIAML2	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	0.4769027548637033	[20]	[161]	4	hSpCas9	negative selection	12258568
159203593	159203616	5	-	28162770	OCIAML2	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	-0.30070482379984886	[11]	[53]	-2	hSpCas9	negative selection	12258569
159162920	159162943	5	+	28162770	OCIAML2	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	0.37456844796011524	[42]	[308]	3	hSpCas9	negative selection	12258570
159161493	159161516	5	+	28162770	OCIAML2	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	-0.2689959640725106	[14]	[68]	-2	hSpCas9	negative selection	12258571
159161352	159161375	5	-	28162770	OCIAML2	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-1.2262110975757146	[64]	[153]	-7	hSpCas9	negative selection	12258572
159203569	159203592	5	-	28162770	OCIAML2	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	-0.34863930086355066	[84]	[369]	-3	hSpCas9	negative selection	12258573
159203548	159203571	5	-	28162770	OCIAML2	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	-0.4311014610555237	[17]	[73]	-3	hSpCas9	negative selection	12258574
159174119	159174142	5	+	28162770	OCIAML2	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	0.1408048868401861	[8]	[54]	1	hSpCas9	negative selection	12258575
159161472	159161495	5	+	28162770	OCIAML2	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	0.028402496691819046	[48]	[276]	0	hSpCas9	negative selection	12258576
159161559	159161582	5	-	28162770	OCIAML3	viability	GGAATTCAGAAAAGAGCCAGTGG	RNF145	ENSG00000145860	0.34709867062226823	[49]	[191]	3	hSpCas9	negative selection	12427933
159174098	159174121	5	+	28162770	OCIAML3	viability	GGACTACCAGTTGATTCCACAGG	RNF145	ENSG00000145860	-0.20794920801708527	[43]	[114]	-2	hSpCas9	negative selection	12427934
159203593	159203616	5	-	28162770	OCIAML3	viability	GGCTGCAAAGGAGAAACTGGAGG	RNF145	ENSG00000145860	-0.15343504893818194	[13]	[37]	-1	hSpCas9	negative selection	12427935
159162920	159162943	5	+	28162770	OCIAML3	viability	TCATAGGCTTACCTGAAGAGAGG	RNF145	ENSG00000145860	0.28700432345875004	[59]	[220]	2	hSpCas9	negative selection	12427936
159161493	159161516	5	+	28162770	OCIAML3	viability	GGGCCACAAGAAACTCCAGCAGG	RNF145	ENSG00000145860	1.38461870888327	[16]	[133]	9	hSpCas9	negative selection	12427937
159161352	159161375	5	-	28162770	OCIAML3	viability	GAAGAGCTTTCTTCTCCGCAGGG	RNF145	ENSG00000145860	-0.38931722072117436	[81]	[188]	-3	hSpCas9	negative selection	12427938
159203569	159203592	5	-	28162770	OCIAML3	viability	AGTGTTAAATGTGGCCCTGAGGG	RNF145	ENSG00000145860	0.4109930407342033	[143]	[577]	4	hSpCas9	negative selection	12427939
159203548	159203571	5	-	28162770	OCIAML3	viability	GGTGCCAAGCATCATGCTGTTGG	RNF145	ENSG00000145860	1.0258886505063802	[33]	[208]	8	hSpCas9	negative selection	12427940
159174119	159174142	5	+	28162770	OCIAML3	viability	GGGACATTCCCAAGGCGAGAAGG	RNF145	ENSG00000145860	0.16680469579641066	[17]	[60]	1	hSpCas9	negative selection	12427941
159161472	159161495	5	+	28162770	OCIAML3	viability	CGCCATAGGCCACCACACAGAGG	RNF145	ENSG00000145860	-0.10858081315392154	[89]	[251]	-1	hSpCas9	negative selection	12427942