Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 284996
• Symbol: RNF149
• Description: ring finger protein 149

DataSource: http://genomecrispr.dkfz.de/#!/results/RNF149

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
101274294	101274317	2	-	26472758	Jiyoye	viability	GGGTCCTGGCATCTTGTCCATGG	RNF149	ENSG00000163162	-3.955394697878835	[143]	[6]	-9	hSpCas9	negative selection	124878
101308577	101308600	2	-	26472758	Jiyoye	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	0.7394950822398314	[165]	[208]	5	hSpCas9	negative selection	138034
101295079	101295102	2	-	26472758	Jiyoye	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	-0.9147527133814889	[224]	[89]	-6	hSpCas9	negative selection	138035
101308319	101308342	2	+	26472758	Jiyoye	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	0.13621405990045077	[145]	[120]	1	hSpCas9	negative selection	138036
101286127	101286150	2	+	26472758	Jiyoye	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	-0.1817560214182284	[181]	[120]	-1	hSpCas9	negative selection	138037
101281993	101282016	2	+	26472758	Jiyoye	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-0.2750843205701976	[68]	[42]	-2	hSpCas9	negative selection	138038
101308415	101308438	2	+	26472758	Jiyoye	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	1.1727101278688508	[29]	[50]	7	hSpCas9	negative selection	138039
101308172	101308195	2	+	26472758	Jiyoye	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	-0.8304034436452505	[190]	[80]	-5	hSpCas9	negative selection	138040
101281921	101281944	2	+	26472758	Jiyoye	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	-0.3412858514981623	[125]	[74]	-2	hSpCas9	negative selection	138041
101308426	101308449	2	-	26472758	Jiyoye	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	0.14937762403822674	[54]	[45]	1	hSpCas9	negative selection	138042
101308245	101308268	2	+	26472758	Jiyoye	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	-1.0078621177729703	[23]	[8]	-6	hSpCas9	negative selection	138043
101274294	101274317	2	-	26472758	KBM7	viability	GGGTCCTGGCATCTTGTCCATGG	RNF149	ENSG00000163162	-5.154653382515178	[374,290]	[6,1]	-9	hSpCas9	negative selection	315996
101308577	101308600	2	-	26472758	KBM7	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	-0.11260370834284938	[1215,682]	[344,454]	-1	hSpCas9	negative selection	329152
101295079	101295102	2	-	26472758	KBM7	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.2629387094262704	[666,680]	[419,348]	2	hSpCas9	negative selection	329153
101308319	101308342	2	+	26472758	KBM7	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	0.45952940495165445	[581,326]	[383,199]	5	hSpCas9	negative selection	329154
101286127	101286150	2	+	26472758	KBM7	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	-0.21490278835464074	[645,442]	[274,165]	-2	hSpCas9	negative selection	329155
101281993	101282016	2	+	26472758	KBM7	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-0.22764448377809066	[281,164]	[157,24]	-2	hSpCas9	negative selection	329156
101308415	101308438	2	+	26472758	KBM7	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	-0.7729457590284436	[203,185]	[59,47]	-6	hSpCas9	negative selection	329157
101308172	101308195	2	+	26472758	KBM7	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	0.07527435719859879	[440,373]	[254,152]	0	hSpCas9	negative selection	329158
101281921	101281944	2	+	26472758	KBM7	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	-0.7177209251980571	[726,677]	[217,185]	-5	hSpCas9	negative selection	329159
101308426	101308449	2	-	26472758	KBM7	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	0.1261949129395143	[333,350]	[241,118]	1	hSpCas9	negative selection	329160
101308245	101308268	2	+	26472758	KBM7	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	0.6924586682504688	[93,87]	[73,64]	7	hSpCas9	negative selection	329161
101274294	101274317	2	-	26472758	Raji	viability	GGGTCCTGGCATCTTGTCCATGG	RNF149	ENSG00000163162	-3.922363808020453	[195]	[2]	-9	hSpCas9	negative selection	507114
101308577	101308600	2	-	26472758	Raji	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	0.31927909221559236	[334]	[96]	3	hSpCas9	negative selection	520270
101295079	101295102	2	-	26472758	Raji	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	-0.7693450897246668	[425]	[57]	-5	hSpCas9	negative selection	520271
101308319	101308342	2	+	26472758	Raji	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	0.1936392687240183	[210]	[55]	1	hSpCas9	negative selection	520272
101286127	101286150	2	+	26472758	Raji	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	0.3444227326744488	[223]	[65]	3	hSpCas9	negative selection	520273
101281993	101282016	2	+	26472758	Raji	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	0.18599337006996586	[124]	[32]	1	hSpCas9	negative selection	520274
101308415	101308438	2	+	26472758	Raji	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	-0.7450592762125428	[64]	[8]	-5	hSpCas9	negative selection	520275
101308172	101308195	2	+	26472758	Raji	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	-0.3188812193284986	[171]	[31]	-3	hSpCas9	negative selection	520276
101281921	101281944	2	+	26472758	Raji	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	0.06696926692769145	[361]	[87]	0	hSpCas9	negative selection	520277
101308426	101308449	2	-	26472758	Raji	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	1.0268936175132317	[128]	[60]	8	hSpCas9	negative selection	520278
101308245	101308268	2	+	26472758	Raji	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	1.0799027989514924	[52]	[25]	8	hSpCas9	negative selection	520279
101274294	101274317	2	-	26472758	K562	viability	GGGTCCTGGCATCTTGTCCATGG	RNF149	ENSG00000163162	-6.490290892559392	[212]	[1]	-9	hSpCas9	negative selection	698232
101308577	101308600	2	-	26472758	K562	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	0.5878621432086092	[598]	[759]	5	hSpCas9	negative selection	711388
101295079	101295102	2	-	26472758	K562	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.637900083578843	[589]	[774]	5	hSpCas9	negative selection	711389
101308319	101308342	2	+	26472758	K562	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	-0.22733316260671854	[293]	[211]	-1	hSpCas9	negative selection	711390
101286127	101286150	2	+	26472758	K562	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	0.7088223042662702	[315]	[435]	6	hSpCas9	negative selection	711391
101281993	101282016	2	+	26472758	K562	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-1.4754733531408177	[223]	[67]	-6	hSpCas9	negative selection	711392
101308415	101308438	2	+	26472758	K562	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	0.8505045199533573	[112]	[171]	7	hSpCas9	negative selection	711393
101308172	101308195	2	+	26472758	K562	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	0.8556925055034504	[325]	[497]	7	hSpCas9	negative selection	711394
101281921	101281944	2	+	26472758	K562	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	0.10583614998371843	[534]	[485]	0	hSpCas9	negative selection	711395
101308426	101308449	2	-	26472758	K562	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	-0.08287587697073082	[403]	[321]	0	hSpCas9	negative selection	711396
101308245	101308268	2	+	26472758	K562	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	0.8293812283876032	[99]	[149]	7	hSpCas9	negative selection	711397
101277226	101277249	2	+	26627737	DLD1	viability	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-0.8991313083652723	[624]	[86,145,85]	-7	hSpCas9	negative selection	807979
101277271	101277294	2	-	26627737	DLD1	viability	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	2.1152247205215855	[9]	[39,0,0]	9	hSpCas9	negative selection	807980
101281906	101281929	2	+	26627737	DLD1	viability	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	0.8498141177864724	[363]	[223,258,143]	7	hSpCas9	negative selection	807981
101281978	101282001	2	+	26627737	DLD1	viability	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	0.5254332714970005	[145]	[62,78,56]	5	hSpCas9	negative selection	807982
101308121	101308144	2	+	26627737	DLD1	viability	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.8537000069657322	[992]	[179,215,127]	-7	hSpCas9	negative selection	807983
101308129	101308152	2	-	26627737	DLD1	viability	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.20005864186147848	[1494]	[407,784,442]	2	hSpCas9	negative selection	807984
101277226	101277249	2	+	26627737	GBM cells	viability after 5 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-0.4807297178579641	[254]	[92,102]	-6	hSpCas9	negative selection	890294
101277271	101277294	2	-	26627737	GBM cells	viability after 5 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-0.42301422000167666	[9]	[5,1]	-6	hSpCas9	negative selection	890295
101281906	101281929	2	+	26627737	GBM cells	viability after 5 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	0.30500241743704654	[282]	[207,166]	5	hSpCas9	negative selection	890296
101281978	101282001	2	+	26627737	GBM cells	viability after 5 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	1.2208419697730477	[53]	[52,81]	9	hSpCas9	negative selection	890297
101308121	101308144	2	+	26627737	GBM cells	viability after 5 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-1.0911706562492318	[434]	[117,100]	-9	hSpCas9	negative selection	890298
101308129	101308152	2	-	26627737	GBM cells	viability after 5 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	-0.031050355622159076	[582]	[369,241]	0	hSpCas9	negative selection	890299
101277226	101277249	2	+	26627737	GBM cells	viability after 13 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-0.5067707952187415	[254]	[87,104]	-6	hSpCas9	negative selection	972609
101277271	101277294	2	-	26627737	GBM cells	viability after 13 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	0.1696797136750332	[9]	[4,6]	2	hSpCas9	negative selection	972610
101281906	101281929	2	+	26627737	GBM cells	viability after 13 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	-0.08696887889175162	[282]	[175,118]	-1	hSpCas9	negative selection	972611
101281978	101282001	2	+	26627737	GBM cells	viability after 13 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	1.0109370525693164	[53]	[79,41]	9	hSpCas9	negative selection	972612
101308121	101308144	2	+	26627737	GBM cells	viability after 13 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.9096198065692248	[434]	[91,152]	-8	hSpCas9	negative selection	972613
101308129	101308152	2	-	26627737	GBM cells	viability after 13 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.4076067491819564	[582]	[439,402]	5	hSpCas9	negative selection	972614
101277226	101277249	2	+	26627737	GBM cells	viability after 21 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-0.8904401700462916	[254]	[80,68]	-6	hSpCas9	negative selection	1054924
101277271	101277294	2	-	26627737	GBM cells	viability after 21 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-1.1326479916810737	[9]	[2,1]	-7	hSpCas9	negative selection	1054925
101281906	101281929	2	+	26627737	GBM cells	viability after 21 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	-0.0919418725734346	[282]	[149,138]	-1	hSpCas9	negative selection	1054926
101281978	101282001	2	+	26627737	GBM cells	viability after 21 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	0.07539940566475423	[53]	[32,28]	0	hSpCas9	negative selection	1054927
101308121	101308144	2	+	26627737	GBM cells	viability after 21 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-1.215202013603695	[434]	[94,107]	-7	hSpCas9	negative selection	1054928
101308129	101308152	2	-	26627737	GBM cells	viability after 21 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.6625075773716431	[582]	[516,486]	6	hSpCas9	negative selection	1054929
101277226	101277249	2	+	26627737	RPE1	viability after 9 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-1.7529656467374206	[1043]	[113,74]	-8	hSpCas9	negative selection	1137239
101277271	101277294	2	-	26627737	RPE1	viability after 9 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	0.3028560768146389	[49]	[17,20]	2	hSpCas9	negative selection	1137240
101281906	101281929	2	+	26627737	RPE1	viability after 9 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	0.5169451326329009	[810]	[206,564]	3	hSpCas9	negative selection	1137241
101281978	101282001	2	+	26627737	RPE1	viability after 9 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	2.0724273514461933	[138]	[165,204]	9	hSpCas9	negative selection	1137242
101308121	101308144	2	+	26627737	RPE1	viability after 9 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.7838829831495068	[2188]	[349,459]	-5	hSpCas9	negative selection	1137243
101308129	101308152	2	-	26627737	RPE1	viability after 9 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.8953714450487867	[875]	[479,548]	6	hSpCas9	negative selection	1137244
101277226	101277249	2	+	26627737	RPE1	viability after 12 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-2.6190259089137364	[1043]	[67,21]	-9	hSpCas9	negative selection	1219554
101277271	101277294	2	-	26627737	RPE1	viability after 12 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	0.4583625596473717	[49]	[16,19]	3	hSpCas9	negative selection	1219555
101281906	101281929	2	+	26627737	RPE1	viability after 12 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	0.37356561698293844	[810]	[172,397]	2	hSpCas9	negative selection	1219556
101281978	101282001	2	+	26627737	RPE1	viability after 12 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	2.0788624945927334	[138]	[200,111]	9	hSpCas9	negative selection	1219557
101308121	101308144	2	+	26627737	RPE1	viability after 12 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.31372567543063967	[2188]	[512,430]	-2	hSpCas9	negative selection	1219558
101308129	101308152	2	-	26627737	RPE1	viability after 12 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.555356794013297	[875]	[459,224]	3	hSpCas9	negative selection	1219559
101277226	101277249	2	+	26627737	RPE1	viability after 15 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-3.6146813150181596	[1043]	[17,29]	-9	hSpCas9	negative selection	1301869
101277271	101277294	2	-	26627737	RPE1	viability after 15 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	0.4422185180531404	[49]	[6,30]	3	hSpCas9	negative selection	1301870
101281906	101281929	2	+	26627737	RPE1	viability after 15 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	0.12061573788961222	[810]	[253,244]	0	hSpCas9	negative selection	1301871
101281978	101282001	2	+	26627737	RPE1	viability after 15 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	2.2442461119262376	[138]	[225,147]	9	hSpCas9	negative selection	1301872
101308121	101308144	2	+	26627737	RPE1	viability after 15 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.24037989989852337	[2188]	[541,506]	-1	hSpCas9	negative selection	1301873
101308129	101308152	2	-	26627737	RPE1	viability after 15 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.3721705922277644	[875]	[335,305]	2	hSpCas9	negative selection	1301874
101277226	101277249	2	+	26627737	RPE1	viability after 18 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-3.9630045212663854	[1043]	[19,15]	-9	hSpCas9	negative selection	1384184
101277271	101277294	2	-	26627737	RPE1	viability after 18 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-0.15505067313951804	[49]	[0,23]	-1	hSpCas9	negative selection	1384185
101281906	101281929	2	+	26627737	RPE1	viability after 18 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	-0.8532194965219514	[810]	[110,131]	-5	hSpCas9	negative selection	1384186
101281978	101282001	2	+	26627737	RPE1	viability after 18 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	2.3054311302647554	[138]	[226,140]	9	hSpCas9	negative selection	1384187
101308121	101308144	2	+	26627737	RPE1	viability after 18 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.1837309197038084	[2188]	[493,547]	-1	hSpCas9	negative selection	1384188
101308129	101308152	2	-	26627737	RPE1	viability after 18 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.12883554340679976	[875]	[228,289]	0	hSpCas9	negative selection	1384189
101277226	101277249	2	+	26627737	HeLa	viability after 8 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-1.517810864034757	[495]	[91,50,85]	-9	hSpCas9	negative selection	1466499
101277271	101277294	2	-	26627737	HeLa	viability after 8 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-0.5283476183287226	[44]	[10,27,1]	-5	hSpCas9	negative selection	1466500
101281906	101281929	2	+	26627737	HeLa	viability after 8 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	-0.21957788824648183	[572]	[283,251,127]	-2	hSpCas9	negative selection	1466501
101281978	101282001	2	+	26627737	HeLa	viability after 8 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	-0.027817527792006747	[136]	[64,10,97]	0	hSpCas9	negative selection	1466502
101308121	101308144	2	+	26627737	HeLa	viability after 8 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.7687181480817433	[1018]	[310,295,189]	-6	hSpCas9	negative selection	1466503
101308129	101308152	2	-	26627737	HeLa	viability after 8 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.4455405488228782	[493]	[383,246,268]	4	hSpCas9	negative selection	1466504
101277226	101277249	2	+	26627737	HeLa	viability after 12 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-0.8265718715288188	[495]	[129,135,78]	-6	hSpCas9	negative selection	1548814
101277271	101277294	2	-	26627737	HeLa	viability after 12 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-0.14607961179315998	[44]	[47,0,3]	-1	hSpCas9	negative selection	1548815
101281906	101281929	2	+	26627737	HeLa	viability after 12 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	-1.3296439859213884	[572]	[57,146,70]	-8	hSpCas9	negative selection	1548816
101281978	101282001	2	+	26627737	HeLa	viability after 12 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	-0.13293108319612545	[136]	[36,74,39]	-1	hSpCas9	negative selection	1548817
101308121	101308144	2	+	26627737	HeLa	viability after 12 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.6784479123201215	[1018]	[284,168,345]	-6	hSpCas9	negative selection	1548818
101308129	101308152	2	-	26627737	HeLa	viability after 12 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.6146253145169258	[493]	[558,160,240]	5	hSpCas9	negative selection	1548819
101277226	101277249	2	+	26627737	HeLa	viability after 15 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-0.47980399615721536	[495]	[171,177,78]	-4	hSpCas9	negative selection	1631129
101277271	101277294	2	-	26627737	HeLa	viability after 15 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-0.10447749580293086	[44]	[0,0,51]	-1	hSpCas9	negative selection	1631130
101281906	101281929	2	+	26627737	HeLa	viability after 15 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	-0.7281348833170139	[572]	[36,146,247]	-6	hSpCas9	negative selection	1631131
101281978	101282001	2	+	26627737	HeLa	viability after 15 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	0.4440185636920897	[136]	[94,60,70]	3	hSpCas9	negative selection	1631132
101308121	101308144	2	+	26627737	HeLa	viability after 15 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.9947867495932978	[1018]	[196,166,264]	-7	hSpCas9	negative selection	1631133
101308129	101308152	2	-	26627737	HeLa	viability after 15 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.3946839514666691	[493]	[238,283,270]	3	hSpCas9	negative selection	1631134
101277226	101277249	2	+	26627737	HeLa	viability after 18 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-0.4701921199257627	[495]	[119,143,78]	-4	hSpCas9	negative selection	1713444
101277271	101277294	2	-	26627737	HeLa	viability after 18 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-0.08430911093687632	[44]	[0,0,51]	0	hSpCas9	negative selection	1713445
101281906	101281929	2	+	26627737	HeLa	viability after 18 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	-0.6948229680352921	[572]	[30,121,247]	-6	hSpCas9	negative selection	1713446
101281978	101282001	2	+	26627737	HeLa	viability after 18 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	0.4542504383763062	[136]	[65,48,70]	4	hSpCas9	negative selection	1713447
101308121	101308144	2	+	26627737	HeLa	viability after 18 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.9862782252618456	[1018]	[137,133,264]	-7	hSpCas9	negative selection	1713448
101308129	101308152	2	-	26627737	HeLa	viability after 18 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.3586420690415887	[493]	[150,230,270]	3	hSpCas9	negative selection	1713449
101277226	101277249	2	+	26627737	HCT116	viability after 6 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	0.567565152228122	[525]	[21,177]	3	hSpCas9	negative selection	1795759
101277271	101277294	2	-	26627737	HCT116	viability after 6 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-2.79017136144973	[43]	[0,0]	-9	hSpCas9	negative selection	1795760
101281906	101281929	2	+	26627737	HCT116	viability after 6 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	-1.049242754751192	[693]	[131,8]	-6	hSpCas9	negative selection	1795761
101281978	101282001	2	+	26627737	HCT116	viability after 6 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	0.04711547891268031	[330]	[143,3]	0	hSpCas9	negative selection	1795762
101308121	101308144	2	+	26627737	HCT116	viability after 6 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	0.160285445529468	[947]	[230,130]	0	hSpCas9	negative selection	1795763
101308129	101308152	2	-	26627737	HCT116	viability after 6 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	1.5129879839970477	[1200]	[485,567]	7	hSpCas9	negative selection	1795764
101277226	101277249	2	+	26627737	HCT116	viability after 8 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	0.1230556430235289	[208]	[150,123,101]	1	hSpCas9	negative selection	1878074
101277271	101277294	2	-	26627737	HCT116	viability after 8 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-1.155670432535362	[26]	[4,7,6]	-8	hSpCas9	negative selection	1878075
101281906	101281929	2	+	26627737	HCT116	viability after 8 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	0.30876774078884206	[348]	[268,194,250]	3	hSpCas9	negative selection	1878076
101281978	101282001	2	+	26627737	HCT116	viability after 8 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	0.1155768261417719	[142]	[119,73,62]	1	hSpCas9	negative selection	1878077
101308121	101308144	2	+	26627737	HCT116	viability after 8 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.16165962379175952	[377]	[194,112,249]	-2	hSpCas9	negative selection	1878078
101308129	101308152	2	-	26627737	HCT116	viability after 8 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.44123645890067953	[481]	[410,331,339]	4	hSpCas9	negative selection	1878079
101277226	101277249	2	+	26627737	HCT116	viability after 9 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	0.08200822126031485	[525]	[127,164]	0	hSpCas9	negative selection	1960389
101277271	101277294	2	-	26627737	HCT116	viability after 9 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-2.134538552833169	[43]	[0,3]	-8	hSpCas9	negative selection	1960390
101281906	101281929	2	+	26627737	HCT116	viability after 9 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	-0.2015940885425405	[693]	[216,116]	-1	hSpCas9	negative selection	1960391
101281978	101282001	2	+	26627737	HCT116	viability after 9 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	0.66107662840069	[330]	[246,54]	5	hSpCas9	negative selection	1960392
101308121	101308144	2	+	26627737	HCT116	viability after 9 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	0.28981117423093494	[947]	[266,342]	2	hSpCas9	negative selection	1960393
101308129	101308152	2	-	26627737	HCT116	viability after 9 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	1.1381070932785042	[1200]	[988,481]	7	hSpCas9	negative selection	1960394
101277226	101277249	2	+	26627737	HCT116	viability after 12 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-0.3158331770582572	[208]	[114,72,73]	-3	hSpCas9	negative selection	2042704
101277271	101277294	2	-	26627737	HCT116	viability after 12 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-1.699772437180128	[26]	[5,5,0]	-9	hSpCas9	negative selection	2042705
101281906	101281929	2	+	26627737	HCT116	viability after 12 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	0.484555435866704	[348]	[411,206,135]	5	hSpCas9	negative selection	2042706
101281978	101282001	2	+	26627737	HCT116	viability after 12 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	0.3555949601212277	[142]	[135,14,131]	3	hSpCas9	negative selection	2042707
101308121	101308144	2	+	26627737	HCT116	viability after 12 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	0.011135817308966567	[377]	[179,144,275]	0	hSpCas9	negative selection	2042708
101308129	101308152	2	-	26627737	HCT116	viability after 12 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.7079397439405398	[481]	[538,442,248]	6	hSpCas9	negative selection	2042709
101277226	101277249	2	+	26627737	HCT116	viability after 15 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	0.4223945810140965	[208]	[237,179,74]	4	hSpCas9	negative selection	2125019
101277271	101277294	2	-	26627737	HCT116	viability after 15 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-2.457440902365647	[26]	[6,0,0]	-9	hSpCas9	negative selection	2125020
101281906	101281929	2	+	26627737	HCT116	viability after 15 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	0.30608369281209413	[348]	[318,345,88]	3	hSpCas9	negative selection	2125021
101281978	101282001	2	+	26627737	HCT116	viability after 15 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	0.04388548043496843	[142]	[111,34,109]	0	hSpCas9	negative selection	2125022
101308121	101308144	2	+	26627737	HCT116	viability after 15 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.4410944311916124	[377]	[249,108,131]	-4	hSpCas9	negative selection	2125023
101308129	101308152	2	-	26627737	HCT116	viability after 15 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.5202630513682037	[481]	[506,515,183]	5	hSpCas9	negative selection	2125024
101277226	101277249	2	+	26627737	HCT116	viability after 18 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	0.3545180450433828	[208]	[97,103,189]	3	hSpCas9	negative selection	2207334
101277271	101277294	2	-	26627737	HCT116	viability after 18 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-2.7111063327989786	[26]	[3,0,0]	-9	hSpCas9	negative selection	2207335
101281906	101281929	2	+	26627737	HCT116	viability after 18 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	0.9465202596158211	[348]	[496,395,65]	7	hSpCas9	negative selection	2207336
101281978	101282001	2	+	26627737	HCT116	viability after 18 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	0.32205574235851975	[142]	[110,52,97]	3	hSpCas9	negative selection	2207337
101308121	101308144	2	+	26627737	HCT116	viability after 18 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.031005098571815326	[377]	[210,84,249]	0	hSpCas9	negative selection	2207338
101308129	101308152	2	-	26627737	HCT116	viability after 18 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.6565558534352619	[481]	[339,283,488]	5	hSpCas9	negative selection	2207339
101275716	101275739	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCGCGCCCGG	RNF149	ENSG00000163162	-0.8581528486253212	[26,35]	[2,3]	-5	dCas9-VP64	positive selection	2392133
101284967	101284990	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCTGCCTCCCAG	RNF149	ENSG00000163162	0.3736894149735144	[619,564]	[67,277]	1	dCas9-VP64	positive selection	2443999
101275716	101275739	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCGCGCCCGG	RNF149	ENSG00000163162	-0.2201981089703296	[184,135]	[60,29]	-2	dCas9-VP64	positive selection	2487388
101284967	101284990	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCTGCCTCCCAG	RNF149	ENSG00000163162	2.2699980135687987	[309,268]	[879,61]	8	dCas9-VP64	positive selection	2539254
101308173	101308196	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	0.5833527472067279	[2,3]	[1,5]	9	hSpCas9	positive selection	3017201
101308449	101308472	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	-0.7006920827133309	[3,3]	[3,0]	-8	hSpCas9	positive selection	3017202
101308323	101308346	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCCCGGCGGAGACCTCGAGGG	RNF149	ENSG00000163162	-1.60562114623519	[2,2]	[0,0]	-9	hSpCas9	positive selection	3017203
101308426	101308449	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	1.0981829603738196	[2,2]	[3,5]	9	hSpCas9	positive selection	3017204
101308173	101308196	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	-1.18336974111723	[2,2]	[0,0]	-9	hSpCas9	positive selection	3085059
101308449	101308472	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	0.3628189625382762	[3,3]	[3,3]	6	hSpCas9	positive selection	3085060
101308323	101308346	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCCCGGCGGAGACCTCGAGGG	RNF149	ENSG00000163162	-0.8465407048985492	[2,2]	[1,0]	-9	hSpCas9	positive selection	3085061
101308426	101308449	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	0.029740189094802083	[2,2]	[3,0]	0	hSpCas9	positive selection	3085062
101294051	101294074		-	24336571	A375	resistance to PLX after 7 days	AAAGAAACTAAGAAAGTTATTGG	RNF149	ENSG00000163162	-0.15231364049775986	[4,3]	[3,3]	-5	hSpCas9	positive selection	3141258
101308159	101308182		+	24336571	A375	resistance to PLX after 7 days	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	0.2083058732383678	[1,2]	[2,2]	6	hSpCas9	positive selection	3141260
101308447	101308470		-	24336571	A375	resistance to PLX after 7 days	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.01785876499853987	[11,13]	[10,13]	0	hSpCas9	positive selection	3141261
101294021	101294044		-	24336571	A375	resistance to PLX after 7 days	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	-0.4507931357456805	[4,4]	[2,2]	-9	hSpCas9	positive selection	3141262
101294028	101294051		+	24336571	A375	resistance to PLX after 7 days	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.13276624945564408	[2,3]	[3,3]	4	hSpCas9	positive selection	3141263
101294051	101294074		-	24336571	A375	resistance to PLX after 14 days	AAAGAAACTAAGAAAGTTATTGG	RNF149	ENSG00000163162	0.27243515682067465	[4,5]	[2,2]	2	hSpCas9	positive selection	3199051
101308159	101308182		+	24336571	A375	resistance to PLX after 14 days	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	0.6501004626871558	[2,1]	[1,1]	6	hSpCas9	positive selection	3199053
101308447	101308470		-	24336571	A375	resistance to PLX after 14 days	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.631761880048463	[11,5]	[5,5]	5	hSpCas9	positive selection	3199054
101294021	101294044		-	24336571	A375	resistance to PLX after 14 days	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.006271865313737468	[1,5]	[1,1]	0	hSpCas9	positive selection	3199055
101294028	101294051		+	24336571	A375	resistance to PLX after 14 days	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	1.1764599019652668	[1,1]	[1,1]	8	hSpCas9	positive selection	3199056
101294051	101294074		-	24336571	A375	viability after 7 days	AAAGAAACTAAGAAAGTTATTGG	RNF149	ENSG00000163162	-0.48608233194452266	[6]	[4,3]	-6	hSpCas9	negative selection	3256844
101308159	101308182		+	24336571	A375	viability after 7 days	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.3066110724784381	[2]	[1,2]	-4	hSpCas9	negative selection	3256846
101308447	101308470		-	24336571	A375	viability after 7 days	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.13865715070521867	[11]	[11,13]	2	hSpCas9	negative selection	3256847
101294021	101294044		-	24336571	A375	viability after 7 days	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	-0.023587874374819684	[4]	[4,4]	0	hSpCas9	negative selection	3256848
101294028	101294051		+	24336571	A375	viability after 7 days	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.4930213542148987	[4]	[2,3]	-6	hSpCas9	negative selection	3256849
101294051	101294074		-	24336571	A375	viability after 14 days	AAAGAAACTAAGAAAGTTATTGG	RNF149	ENSG00000163162	-0.2160670538505547	[6]	[4,5]	-3	hSpCas9	negative selection	3314637
101308159	101308182		+	24336571	A375	viability after 14 days	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.3750774056331525	[2]	[2,1]	-4	hSpCas9	negative selection	3314639
101308447	101308470		-	24336571	A375	viability after 14 days	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.3283452271488033	[11]	[11,5]	-4	hSpCas9	negative selection	3314640
101294021	101294044		-	24336571	A375	viability after 14 days	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	-0.21196900172747668	[4]	[1,5]	-2	hSpCas9	negative selection	3314641
101294028	101294051		+	24336571	A375	viability after 14 days	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-1.0487638171125497	[4]	[1,1]	-8	hSpCas9	negative selection	3314642
101294021	101294044	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	-0.3573836326693731	[195,195]	[0,0]	-2	hSpCas9	positive selection	3390109
101288998	101289021	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.6574133692587072	[96,96]	[0,0]	3	hSpCas9	positive selection	3390110
101308284	101308307	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	-2.030386168103614	[624,624]	[0,0]	-9	hSpCas9	positive selection	3390111
101308172	101308195	2	+	26780180	HT29	viability (Avana library 4 designs)	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	2.69479994956081	[]	[]	8	hSpCas9	negative selection	3455572
101308448	101308471	2	+	26780180	HT29	viability (Avana library 4 designs)	CACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	0.93436535119578	[]	[]	3	hSpCas9	negative selection	3455573
101308323	101308346	2	-	26780180	HT29	viability (Avana library 4 designs)	GCGCCCGGCGGAGACCTCGAGGG	RNF149	ENSG00000163162	0.906635485335583	[]	[]	3	hSpCas9	negative selection	3455574
101308426	101308449	2	-	26780180	HT29	viability (Avana library 4 designs)	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	1.57798612313277	[]	[]	6	hSpCas9	negative selection	3455575
101308426	101308449	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	2.10094570624137	[]	[]	3	hSpCas9	negative selection	3553628
101308448	101308471	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	1.07280738856515	[]	[]	1	hSpCas9	negative selection	3553629
101308323	101308346	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCCCGGCGGAGACCTCGAGGG	RNF149	ENSG00000163162	3.91448009224339	[]	[]	6	hSpCas9	negative selection	3553630
101308172	101308195	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	1.36525145839986	[]	[]	2	hSpCas9	negative selection	3553631
101308281	101308304	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCTTCGTGCCCGAGCCCGGCGG	RNF149	ENSG00000163162	3.94016071027372	[]	[]	6	hSpCas9	negative selection	3553632
101295049	101295072	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATGTACAGGAGTTCATCAGCGG	RNF149	ENSG00000163162	4.07944966449083	[]	[]	6	hSpCas9	negative selection	3553633
101308426	101308449	2	-	26780180	A375	viability (Avana lentiGuide)	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	-4.37555074857119	[]	[]	-7	hSpCas9	negative selection	3662287
101308448	101308471	2	+	26780180	A375	viability (Avana lentiGuide)	CACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	1.8445522323795	[]	[]	2	hSpCas9	negative selection	3662288
101308323	101308346	2	-	26780180	A375	viability (Avana lentiGuide)	GCGCCCGGCGGAGACCTCGAGGG	RNF149	ENSG00000163162	5.41693513830659	[]	[]	5	hSpCas9	negative selection	3662289
101308172	101308195	2	+	26780180	A375	viability (Avana lentiGuide)	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	2.76586858931113	[]	[]	3	hSpCas9	negative selection	3662290
101308281	101308304	2	-	26780180	A375	viability (Avana lentiGuide)	TTCTTCGTGCCCGAGCCCGGCGG	RNF149	ENSG00000163162	2.00711942094372	[]	[]	2	hSpCas9	negative selection	3662291
101295049	101295072	2	-	26780180	A375	viability (Avana lentiGuide)	CATGTACAGGAGTTCATCAGCGG	RNF149	ENSG00000163162	-2.32365613303129	[]	[]	-4	hSpCas9	negative selection	3662292
101308426	101308449	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	-0.17510106183725224	[4]	[5,2]	-3	hSpCas9	positive selection	3770894
101308448	101308471	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	-0.009190233053344779	[5]	[5,4]	0	hSpCas9	positive selection	3770895
101308323	101308346	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCCCGGCGGAGACCTCGAGGG	RNF149	ENSG00000163162	0.1166064392369871	[3]	[2,4]	3	hSpCas9	positive selection	3770896
101308172	101308195	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	0.22906696206497743	[5]	[5,6]	6	hSpCas9	positive selection	3770897
101308281	101308304	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCTTCGTGCCCGAGCCCGGCGG	RNF149	ENSG00000163162	0.30191942016673506	[5]	[7,6]	8	hSpCas9	positive selection	3770898
101295049	101295072	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGTACAGGAGTTCATCAGCGG	RNF149	ENSG00000163162	0.18781006983008638	[6]	[6,6]	5	hSpCas9	positive selection	3770899
101308426	101308449	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	0.32669866954125903	[4]	[4,4]	8	hSpCas9	positive selection	3879501
101308448	101308471	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	-0.3114499932518269	[6]	[3,4]	-4	hSpCas9	positive selection	3879502
101308323	101308346	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCCCGGCGGAGACCTCGAGGG	RNF149	ENSG00000163162	0.04007953081520868	[4]	[3,4]	0	hSpCas9	positive selection	3879503
101308172	101308195	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	0.18394972739704615	[5]	[4,4]	4	hSpCas9	positive selection	3879504
101308281	101308304	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCTTCGTGCCCGAGCCCGGCGG	RNF149	ENSG00000163162	0.20378431912816353	[6]	[6,5]	5	hSpCas9	positive selection	3879505
101295049	101295072	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGTACAGGAGTTCATCAGCGG	RNF149	ENSG00000163162	0.25965740804526466	[6]	[7,6]	7	hSpCas9	positive selection	3879506
101308284	101308307	2	-	26780180	A375	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.258321272863579	[]	[]	0	hSpCas9	negative selection	3989618
101308159	101308182	2	+	26780180	A375	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	1.04794924818641	[]	[]	5	hSpCas9	negative selection	3989619
101308447	101308470	2	-	26780180	A375	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	1.07463077499869	[]	[]	5	hSpCas9	negative selection	3989620
101294021	101294044	2	-	26780180	A375	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.855310458719349	[]	[]	3	hSpCas9	negative selection	3989621
101288998	101289021	2	-	26780180	A375	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.798936637685426	[]	[]	3	hSpCas9	negative selection	3989622
101294028	101294051	2	+	26780180	A375	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	1.75388561189077	[]	[]	9	hSpCas9	negative selection	3989623
101308284	101308307	2	-	26780180	HT29	viability (GeCKOv2 library)	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.711356449238137	[]	[]	2	hSpCas9	negative selection	4097584
101308159	101308182	2	+	26780180	HT29	viability (GeCKOv2 library)	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	0.875864599785241	[]	[]	3	hSpCas9	negative selection	4097585
101308447	101308470	2	-	26780180	HT29	viability (GeCKOv2 library)	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	1.41724171920135	[]	[]	7	hSpCas9	negative selection	4097586
101294021	101294044	2	-	26780180	HT29	viability (GeCKOv2 library)	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	1.34733921462605	[]	[]	7	hSpCas9	negative selection	4097587
101288998	101289021	2	-	26780180	HT29	viability (GeCKOv2 library)	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	1.15906779682936	[]	[]	5	hSpCas9	negative selection	4097588
101294028	101294051	2	+	26780180	HT29	viability (GeCKOv2 library)	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	1.81808771101045	[]	[]	8	hSpCas9	negative selection	4097589
101294051	101294074	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAAGAAACTAAGAAAGTTATTGG	RNF149	ENSG00000163162	-0.17162917779272158	[2]	[0,1]	-4	hSpCas9	positive selection	4166782
101308159	101308182	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.26311284637010024	[1]	[1,0]	-6	hSpCas9	positive selection	4166785
101308447	101308470	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.17537588611921762	[3]	[2,2]	4	hSpCas9	positive selection	4166786
101294021	101294044	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.2394417207223435	[1]	[1,0]	6	hSpCas9	positive selection	4166787
101294028	101294051	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.2548669792678683	[2]	[0,0]	-6	hSpCas9	positive selection	4166788
101294051	101294074	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAAGAAACTAAGAAAGTTATTGG	RNF149	ENSG00000163162	-0.18849358231180846	[2]	[1,0,0,0]	-3	hSpCas9	positive selection	4230804
101308159	101308182	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.4894661808134654	[2]	[0,0,0,0]	-7	hSpCas9	positive selection	4230807
101308447	101308470	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.14153488071438813	[3]	[2,2,0,0]	1	hSpCas9	positive selection	4230808
101294021	101294044	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.23359605215695384	[3]	[3,3,1,0]	1	hSpCas9	positive selection	4230809
101294028	101294051	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	2.146001253774233	[0]	[0,0,0,3]	9	hSpCas9	positive selection	4230810
101308159	101308182	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	0.23364543894709383	[3]	[3,3]	5	hSpCas9	positive selection	4295172
101308447	101308470	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.022210760178239974	[3]	[3,1]	0	hSpCas9	positive selection	4295173
101294028	101294051	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.37425963148561475	[2]	[2,0]	-7	hSpCas9	positive selection	4295174
101294021	101294044	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.06973706181702015	[3]	[2,1]	1	hSpCas9	positive selection	4359426
101288998	101289021	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.4368311168788025	[2]	[2,2]	8	hSpCas9	positive selection	4359427
101308284	101308307	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.23790361944112143	[4]	[4,2]	5	hSpCas9	positive selection	4359428
101295079	101295101	2	-	27760321	OCIAML3	viability	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.665846582057091	[456,375]	[519,506]	7	hSpCas9	negative selection	4435103
101308157	101308179	2	-	27760321	OCIAML3	viability	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	0.0206279268227684	[411,323]	[263,323]	0	hSpCas9	negative selection	4435104
101308382	101308404	2	+	27760321	OCIAML3	viability	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	0.7881419958329332	[316,264]	[324,477]	8	hSpCas9	negative selection	4435105
101308412	101308434	2	+	27760321	OCIAML3	viability	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	-0.18617802515402737	[1052,929]	[665,698]	-2	hSpCas9	negative selection	4435106
101308449	101308471	2	+	27760321	OCIAML3	viability	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	0.5593345592717751	[244,237]	[218,356]	6	hSpCas9	negative selection	4435107
101295079	101295101	2	-	27760321	OCIAML2	viability	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.6235464240624875	[456,375]	[482,560]	8	hSpCas9	negative selection	4518566
101308157	101308179	2	-	27760321	OCIAML2	viability	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	-0.264596808346143	[411,323]	[196,310]	-3	hSpCas9	negative selection	4518567
101308382	101308404	2	+	27760321	OCIAML2	viability	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	0.16582164525152027	[316,264]	[281,237]	2	hSpCas9	negative selection	4518568
101308412	101308434	2	+	27760321	OCIAML2	viability	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	-0.1837709590536094	[1052,929]	[555,900]	-2	hSpCas9	negative selection	4518569
101308449	101308471	2	+	27760321	OCIAML2	viability	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	0.08324631065540722	[244,237]	[231,174]	1	hSpCas9	negative selection	4518570
101295079	101295101	2	-	27760321	MV411	viability	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.5123843528885811	[456,375]	[153,744]	3	hSpCas9	negative selection	4602029
101308157	101308179	2	-	27760321	MV411	viability	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	0.07664458640446808	[411,323]	[279,215]	0	hSpCas9	negative selection	4602030
101308382	101308404	2	+	27760321	MV411	viability	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	0.22165476327734657	[316,264]	[240,195]	1	hSpCas9	negative selection	4602031
101308412	101308434	2	+	27760321	MV411	viability	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	0.5481917477067393	[1052,929]	[725,1298]	4	hSpCas9	negative selection	4602032
101308449	101308471	2	+	27760321	MV411	viability	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	1.2646837620711984	[244,237]	[43,893]	8	hSpCas9	negative selection	4602033
101295079	101295101	2	-	27760321	HL60	viability	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.26256807000469856	[456,375]	[479,327]	3	hSpCas9	negative selection	4685492
101308157	101308179	2	-	27760321	HL60	viability	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	-0.27449577968052924	[411,323]	[309,179]	-3	hSpCas9	negative selection	4685493
101308382	101308404	2	+	27760321	HL60	viability	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	0.8647383074524719	[316,264]	[401,461]	8	hSpCas9	negative selection	4685494
101308412	101308434	2	+	27760321	HL60	viability	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	0.56211202020651	[1052,929]	[949,1451]	6	hSpCas9	negative selection	4685495
101308449	101308471	2	+	27760321	HL60	viability	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	0.32208416742518975	[244,237]	[201,294]	4	hSpCas9	negative selection	4685496
101295079	101295101	2	-	27760321	HT1080	viability	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.9437319530301354	[375,293]	[250,262]	5	hSpCas9	negative selection	4768955
101308157	101308179	2	-	27760321	HT1080	viability	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	-1.9204438131667776	[323,252]	[37,21]	-6	hSpCas9	negative selection	4768956
101308382	101308404	2	+	27760321	HT1080	viability	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	1.508069748943823	[264,206]	[465,49]	8	hSpCas9	negative selection	4768957
101308412	101308434	2	+	27760321	HT1080	viability	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	0.3441796700157882	[929,725]	[412,424]	1	hSpCas9	negative selection	4768958
101308449	101308471	2	+	27760321	HT1080	viability	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	1.2316698302081117	[237,185]	[289,97]	6	hSpCas9	negative selection	4768959
101295079	101295101	2	-	27760321	HT29	viability after 7 days	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.0018112783582267256	[375,293]	[478,386,433]	0	hSpCas9	negative selection	4852418
101308157	101308179	2	-	27760321	HT29	viability after 7 days	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	-0.5246700162105072	[323,252]	[259,176,333]	-6	hSpCas9	negative selection	4852419
101308382	101308404	2	+	27760321	HT29	viability after 7 days	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	-0.16212069378354443	[264,206]	[430,261,146]	-2	hSpCas9	negative selection	4852420
101308412	101308434	2	+	27760321	HT29	viability after 7 days	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	-0.3108799023103309	[929,725]	[916,1035,635]	-4	hSpCas9	negative selection	4852421
101308449	101308471	2	+	27760321	HT29	viability after 7 days	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	-0.39732147477686974	[237,185]	[233,263,128]	-5	hSpCas9	negative selection	4852422
101295079	101295101	2	-	27760321	HT29	viability after 25 days	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.4122307128659851	[375,293]	[456,444,642]	4	hSpCas9	negative selection	4935881
101308157	101308179	2	-	27760321	HT29	viability after 25 days	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	-0.5862409697149429	[323,252]	[131,260,276]	-5	hSpCas9	negative selection	4935882
101308382	101308404	2	+	27760321	HT29	viability after 25 days	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	-0.47007482015617164	[264,206]	[153,249,180]	-4	hSpCas9	negative selection	4935883
101308412	101308434	2	+	27760321	HT29	viability after 25 days	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	0.28689644553687854	[929,725]	[977,1320,1175]	3	hSpCas9	negative selection	4935884
101308449	101308471	2	+	27760321	HT29	viability after 25 days	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	0.3815279989822929	[237,185]	[262,239,461]	4	hSpCas9	negative selection	4935885
101295079	101295101	2	-	27760321	HT29	viability after 22 days	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.17150495028343182	[375,293]	[306,580,423]	1	hSpCas9	negative selection	5019344
101308157	101308179	2	-	27760321	HT29	viability after 22 days	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	-0.6097353117740335	[323,252]	[89,263,305]	-5	hSpCas9	negative selection	5019345
101308382	101308404	2	+	27760321	HT29	viability after 22 days	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	-0.3718488154014442	[264,206]	[231,185,213]	-4	hSpCas9	negative selection	5019346
101308412	101308434	2	+	27760321	HT29	viability after 22 days	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	0.426879767345407	[929,725]	[1255,1446,1156]	4	hSpCas9	negative selection	5019347
101308449	101308471	2	+	27760321	HT29	viability after 22 days	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	-0.27670446658921966	[237,185]	[107,248,252]	-3	hSpCas9	negative selection	5019348
101295079	101295101	2	-	27760321	HT29	viability after 19 days	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	-0.6564960507895902	[375,293]	[264,131,330]	-5	hSpCas9	negative selection	5102807
101308157	101308179	2	-	27760321	HT29	viability after 19 days	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	-0.44109172049172674	[323,252]	[108,203,395]	-4	hSpCas9	negative selection	5102808
101308382	101308404	2	+	27760321	HT29	viability after 19 days	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	-0.5932624074107046	[264,206]	[221,216,104]	-5	hSpCas9	negative selection	5102809
101308412	101308434	2	+	27760321	HT29	viability after 19 days	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	0.34651215555650117	[929,725]	[1010,1183,1388]	3	hSpCas9	negative selection	5102810
101308449	101308471	2	+	27760321	HT29	viability after 19 days	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	0.8122577222201688	[237,185]	[211,142,881]	8	hSpCas9	negative selection	5102811
101295079	101295101	2	-	27760321	HT29	viability after 16 days	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	-0.07646014112166162	[375,293]	[377,299,391]	-1	hSpCas9	negative selection	5186270
101308157	101308179	2	-	27760321	HT29	viability after 16 days	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	-0.35396808383464207	[323,252]	[171,214,363]	-4	hSpCas9	negative selection	5186271
101308382	101308404	2	+	27760321	HT29	viability after 16 days	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	-0.1846776344635127	[264,206]	[151,283,251]	-2	hSpCas9	negative selection	5186272
101308412	101308434	2	+	27760321	HT29	viability after 16 days	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	0.03357966910831256	[929,725]	[953,832,1060]	0	hSpCas9	negative selection	5186273
101308449	101308471	2	+	27760321	HT29	viability after 16 days	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	0.04829596826461435	[237,185]	[189,190,350]	0	hSpCas9	negative selection	5186274
101295079	101295101	2	-	27760321	HT29	viability after 13 days	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	-0.15341151000762843	[375,293]	[226,307,503]	-2	hSpCas9	negative selection	5269733
101308157	101308179	2	-	27760321	HT29	viability after 13 days	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	-0.27506474468153874	[323,252]	[168,247,404]	-3	hSpCas9	negative selection	5269734
101308382	101308404	2	+	27760321	HT29	viability after 13 days	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	0.17058260101290257	[264,206]	[306,386,234]	2	hSpCas9	negative selection	5269735
101308412	101308434	2	+	27760321	HT29	viability after 13 days	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	0.03637192635872921	[929,725]	[1218,927,817]	0	hSpCas9	negative selection	5269736
101308449	101308471	2	+	27760321	HT29	viability after 13 days	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	-0.6324658203789452	[237,185]	[88,89,288]	-6	hSpCas9	negative selection	5269737
101295079	101295101	2	-	27760321	HT29	viability after 10 days	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.47561491238567194	[375,293]	[617,506,616]	6	hSpCas9	negative selection	5353196
101308157	101308179	2	-	27760321	HT29	viability after 10 days	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	-0.3995985054194259	[323,252]	[215,194,402]	-5	hSpCas9	negative selection	5353197
101308382	101308404	2	+	27760321	HT29	viability after 10 days	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	-0.20931631321265365	[264,206]	[196,308,259]	-3	hSpCas9	negative selection	5353198
101308412	101308434	2	+	27760321	HT29	viability after 10 days	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	-0.28071496411075403	[929,725]	[755,874,920]	-4	hSpCas9	negative selection	5353199
101308449	101308471	2	+	27760321	HT29	viability after 10 days	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	-0.17648602352595433	[237,185]	[76,190,428]	-2	hSpCas9	negative selection	5353200
101295079	101295101	2	-	27760321	MOLM13	viability	TAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.2794199979401181	[456,375]	[399,184]	2	hSpCas9	negative selection	5436659
101308157	101308179	2	-	27760321	MOLM13	viability	CTACAATGAGGAGCGCTACGGG	RNF149	ENSG00000163162	-0.2576190216096082	[411,323]	[319,46]	-2	hSpCas9	negative selection	5436660
101308382	101308404	2	+	27760321	MOLM13	viability	GGGCGAGCTGTCGCCGAAGCGG	RNF149	ENSG00000163162	-0.22652858384845365	[316,264]	[21,239]	-1	hSpCas9	negative selection	5436661
101308412	101308434	2	+	27760321	MOLM13	viability	CGAGACGCTCCACACCGTCAGG	RNF149	ENSG00000163162	-0.29099507205853337	[1052,929]	[551,374]	-2	hSpCas9	negative selection	5436662
101308449	101308471	2	+	27760321	MOLM13	viability	ACGTACTCGATGTTTACCACGG	RNF149	ENSG00000163162	-0.7105339776389579	[244,237]	[90,76]	-4	hSpCas9	negative selection	5436663
101308235	101308258	2	+	27661255	K562	viability	GCAGCCCCCACGAGCCACCAGGG	RNF149	ENSG00000163162	-0.22397863741846094	[789,785]	[545,532]	-6	dCas9-KRAB	negative selection	5507854
101308617	101308640	2	+	27661255	K562	viability	GTCAGGGTCACGCGCGAGTGCGG	RNF149	ENSG00000163162	-0.06879838365394597	[509,522]	[437,354]	-3	dCas9-KRAB	negative selection	5507855
101308239	101308262	2	-	27661255	K562	viability	GTCGCCCTGGTGGCTCGTGGGGG	RNF149	ENSG00000163162	0.30533357146593865	[541,548]	[533,541]	8	dCas9-KRAB	negative selection	5507856
101308323	101308346	2	-	27661255	K562	viability	GCGCCCGGCGGAGACCTCGAGGG	RNF149	ENSG00000163162	-0.054351340835045114	[623,644]	[503,473]	-2	dCas9-KRAB	negative selection	5507857
101308534	101308557	2	-	27661255	K562	viability	GGCTCGCGGCGTGTTGGCTCTGG	RNF149	ENSG00000163162	-0.012937281328994521	[389,310]	[310,250]	0	dCas9-KRAB	negative selection	5507858
101308159	101308182	2	+	27260156	BXPC3	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	0.23242749602799928	[764]	[696,1080,957,1047]	5	hSpCas9	negative selection	5567632
101308447	101308470	2	-	27260156	BXPC3	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.32701056093067726	[771]	[897,1144,827,1195]	7	hSpCas9	negative selection	5567633
101294028	101294051	2	+	27260156	BXPC3	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.12095298693349932	[354]	[351,390,425,455]	2	hSpCas9	negative selection	5567634
101294021	101294044	2	-	27260156	BXPC3	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.23794721762602355	[466]	[580,466,510,768]	5	hSpCas9	negative selection	5631886
101288998	101289021	2	-	27260156	BXPC3	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.19190754535650917	[316]	[348,330,396,449]	4	hSpCas9	negative selection	5631887
101308284	101308307	2	-	27260156	BXPC3	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.2979614482660835	[1062]	[1463,1472,1266,1213]	6	hSpCas9	negative selection	5631888
101308159	101308182	2	+	27260156	A673	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.01588086461122229	[764]	[980,881,907,867]	0	hSpCas9	negative selection	5688883
101308447	101308470	2	-	27260156	A673	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.06670130363590154	[771]	[945,833,705,1072]	-2	hSpCas9	negative selection	5688884
101294028	101294051	2	+	27260156	A673	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.13289354448747354	[354]	[552,340,480,508]	3	hSpCas9	negative selection	5688885
101294021	101294044	2	-	27260156	A673	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.2174459386102349	[466]	[740,601,657,614]	5	hSpCas9	negative selection	5753137
101288998	101289021	2	-	27260156	A673	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.26216566512712103	[316]	[412,320,223,322]	-6	hSpCas9	negative selection	5753138
101308284	101308307	2	-	27260156	A673	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.2860707660709434	[1062]	[1852,1386,1473,1546]	6	hSpCas9	negative selection	5753139
101308159	101308182	2	+	27260156	A375	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.2238854378603194	[764]	[1005,939,571,586]	-3	hSpCas9	negative selection	5810134
101308447	101308470	2	-	27260156	A375	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.031794644191710075	[771]	[772,1044,822,902]	0	hSpCas9	negative selection	5810135
101294028	101294051	2	+	27260156	A375	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.08437066354243256	[354]	[368,391,458,347]	-1	hSpCas9	negative selection	5810136
101294021	101294044	2	-	27260156	A375	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.34784024367447164	[466]	[589,747,658,773]	5	hSpCas9	negative selection	5874388
101288998	101289021	2	-	27260156	A375	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.3624691412403426	[316]	[625,357,418,482]	5	hSpCas9	negative selection	5874389
101308284	101308307	2	-	27260156	A375	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.4743956805448455	[1062]	[1711,2085,1713,1462]	7	hSpCas9	negative selection	5874390
101308159	101308182	2	+	27260156	COLO741	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.11210145275048222	[764]	[1096,822,813]	-2	hSpCas9	negative selection	5931385
101308447	101308470	2	-	27260156	COLO741	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.03317072637731633	[771]	[1198,896,949]	0	hSpCas9	negative selection	5931386
101294028	101294051	2	+	27260156	COLO741	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.23561491345677416	[354]	[467,437,264]	-5	hSpCas9	negative selection	5931387
101294021	101294044	2	-	27260156	COLO741	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.2881335514273518	[466]	[812,814,574]	6	hSpCas9	negative selection	5995639
101288998	101289021	2	-	27260156	COLO741	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.020714883284265406	[316]	[459,343,397]	0	hSpCas9	negative selection	5995640
101308284	101308307	2	-	27260156	COLO741	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	1.0387299628418785	[1062]	[1963,1586,4604]	9	hSpCas9	negative selection	5995641
101308159	101308182	2	+	27260156	CAL120	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.6434754109938193	[764]	[695,478,664]	-7	hSpCas9	negative selection	6052636
101308447	101308470	2	-	27260156	CAL120	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.2717814169685825	[771]	[1423,783,1307]	4	hSpCas9	negative selection	6052637
101294028	101294051	2	+	27260156	CAL120	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.05336511957181256	[354]	[522,308,458]	-1	hSpCas9	negative selection	6052638
101294021	101294044	2	-	27260156	CAL120	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.3821613738241225	[466]	[571,973,698]	6	hSpCas9	negative selection	6116890
101288998	101289021	2	-	27260156	CAL120	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.27395476588784823	[316]	[410,601,408]	4	hSpCas9	negative selection	6116891
101308284	101308307	2	-	27260156	CAL120	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.32433847061185417	[1062]	[1794,1597,1596]	5	hSpCas9	negative selection	6116892
101308159	101308182	2	+	27260156	CADOES1	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.22463748484678048	[764]	[615,565,529,727]	-4	hSpCas9	negative selection	6173887
101308447	101308470	2	-	27260156	CADOES1	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.030204281144133427	[771]	[691,668,861,584]	0	hSpCas9	negative selection	6173888
101294028	101294051	2	+	27260156	CADOES1	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.020117935138691867	[354]	[263,340,358,376]	0	hSpCas9	negative selection	6173889
101294021	101294044	2	-	27260156	CADOES1	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.0767377952473829	[466]	[456,341,421,616]	1	hSpCas9	negative selection	6238141
101288998	101289021	2	-	27260156	CADOES1	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.1615559147665674	[316]	[282,210,301,257]	-3	hSpCas9	negative selection	6238142
101308284	101308307	2	-	27260156	CADOES1	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.5910132887679955	[1062]	[1346,1601,1249,1768]	8	hSpCas9	negative selection	6238143
101308159	101308182	2	+	27260156	EWS502	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.445786127749429	[764]	[601,502,766,503]	-6	hSpCas9	negative selection	6295138
101308447	101308470	2	-	27260156	EWS502	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.10906584432482724	[771]	[598,923,780,736]	-2	hSpCas9	negative selection	6295139
101294028	101294051	2	+	27260156	EWS502	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.1288110111122951	[354]	[397,342,599,300]	2	hSpCas9	negative selection	6295140
101294021	101294044	2	-	27260156	EWS502	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	-0.08199918204730126	[466]	[276,493,444,688]	-1	hSpCas9	negative selection	6359392
101288998	101289021	2	-	27260156	EWS502	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.46133030444515066	[316]	[498,371,501,474]	7	hSpCas9	negative selection	6359393
101308284	101308307	2	-	27260156	EWS502	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.33388431864185075	[1062]	[1564,1289,1462,1334]	6	hSpCas9	negative selection	6359394
101308159	101308182	2	+	27260156	EW8	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.5620334611441449	[764]	[432,423,431,388]	-7	hSpCas9	negative selection	6416389
101308447	101308470	2	-	27260156	EW8	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.34054718323886957	[771]	[655,442,432,470]	-6	hSpCas9	negative selection	6416390
101294028	101294051	2	+	27260156	EW8	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.23568531681226074	[354]	[226,300,190,264]	-4	hSpCas9	negative selection	6416391
101294021	101294044	2	-	27260156	EW8	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	-0.02469555068351236	[466]	[607,407,275,237]	0	hSpCas9	negative selection	6480643
101288998	101289021	2	-	27260156	EW8	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.019903162256381335	[316]	[372,272,223,189]	0	hSpCas9	negative selection	6480644
101308284	101308307	2	-	27260156	EW8	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.400588484411984	[1062]	[1339,1007,946,1303]	7	hSpCas9	negative selection	6480645
101308159	101308182	2	+	27260156	CORL105	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.11996123290075178	[764]	[956,615,870,867]	-2	hSpCas9	negative selection	6537640
101308447	101308470	2	-	27260156	CORL105	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.1683740427826078	[771]	[1236,905,1087,852]	3	hSpCas9	negative selection	6537641
101294028	101294051	2	+	27260156	CORL105	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.015412692311753518	[354]	[428,442,393,375]	0	hSpCas9	negative selection	6537642
101294021	101294044	2	-	27260156	CORL105	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.17079209920957641	[466]	[726,438,624,678]	3	hSpCas9	negative selection	6601894
101288998	101289021	2	-	27260156	CORL105	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.21981273782120037	[316]	[371,343,279,273]	-4	hSpCas9	negative selection	6601895
101308284	101308307	2	-	27260156	CORL105	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.2451943984359306	[1062]	[1612,1346,1720,1264]	4	hSpCas9	negative selection	6601896
101308159	101308182	2	+	27260156	HS294T	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.010540166238021786	[764]	[374,259,246,282]	0	hSpCas9	negative selection	6658891
101308447	101308470	2	-	27260156	HS294T	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.1870449178257485	[771]	[288,366,336,374]	2	hSpCas9	negative selection	6658892
101294028	101294051	2	+	27260156	HS294T	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.7388944381796557	[354]	[137,143,452,184]	8	hSpCas9	negative selection	6658893
101294021	101294044	2	-	27260156	HS294T	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.5336865678194871	[466]	[381,203,236,201]	7	hSpCas9	negative selection	6723145
101288998	101289021	2	-	27260156	HS294T	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.261614989074191	[316]	[131,87,109,70]	-4	hSpCas9	negative selection	6723146
101308284	101308307	2	-	27260156	HS294T	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.4206581661331237	[1062]	[513,605,531,547]	5	hSpCas9	negative selection	6723147
101308159	101308182	2	+	27260156	HCC44	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.8805010749085185	[764]	[567,341,582,430]	-8	hSpCas9	negative selection	6780142
101308447	101308470	2	-	27260156	HCC44	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.47118183335771024	[771]	[567,489,781,711]	-6	hSpCas9	negative selection	6780143
101294028	101294051	2	+	27260156	HCC44	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.21156271895271808	[354]	[579,157,643,555]	3	hSpCas9	negative selection	6780144
101294021	101294044	2	-	27260156	HCC44	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	-0.08808657743139878	[466]	[598,330,619,487]	-1	hSpCas9	negative selection	6844396
101288998	101289021	2	-	27260156	HCC44	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.1717279325589911	[316]	[293,254,491,267]	-3	hSpCas9	negative selection	6844397
101308284	101308307	2	-	27260156	HCC44	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.5131044373629827	[1062]	[1856,1374,2004,1722]	8	hSpCas9	negative selection	6844398
101308159	101308182	2	+	27260156	G402	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.2504847086991023	[764]	[1039,536,920,665]	-3	hSpCas9	negative selection	6901393
101308447	101308470	2	-	27260156	G402	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.28271900115869225	[771]	[731,1161,445,770]	-4	hSpCas9	negative selection	6901394
101294028	101294051	2	+	27260156	G402	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.09608212044344044	[354]	[615,492,406,362]	1	hSpCas9	negative selection	6901395
101294021	101294044	2	-	27260156	G402	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	-0.188496461317394	[466]	[719,471,455,385]	-2	hSpCas9	negative selection	6965647
101288998	101289021	2	-	27260156	G402	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.9692356325374729	[316]	[698,527,289,1452]	9	hSpCas9	negative selection	6965648
101308284	101308307	2	-	27260156	G402	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.5584356556629781	[1062]	[2491,1893,1900,1451]	7	hSpCas9	negative selection	6965649
101308159	101308182	2	+	27260156	L33	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.2673227774805283	[764]	[508,289,418,661]	-6	hSpCas9	negative selection	7022644
101308447	101308470	2	-	27260156	L33	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.1259272052060959	[771]	[839,324,576,818]	3	hSpCas9	negative selection	7022645
101294028	101294051	2	+	27260156	L33	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.25516154321879086	[354]	[246,169,204,203]	-5	hSpCas9	negative selection	7022646
101294021	101294044	2	-	27260156	L33	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.043214518850749485	[466]	[398,185,298,596]	1	hSpCas9	negative selection	7086898
101288998	101289021	2	-	27260156	L33	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.32401521987917203	[316]	[305,90,147,247]	-6	hSpCas9	negative selection	7086899
101308284	101308307	2	-	27260156	L33	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.12275070842388502	[1062]	[1042,552,722,1089]	2	hSpCas9	negative selection	7086900
101308159	101308182	2	+	27260156	K562	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.09858439675423503	[764]	[1252,580,477,307]	-1	hSpCas9	negative selection	7143895
101308447	101308470	2	-	27260156	K562	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.24652096547085134	[771]	[590,1011,250,487]	-3	hSpCas9	negative selection	7143896
101294028	101294051	2	+	27260156	K562	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.2887392711436093	[354]	[567,338,481,184]	3	hSpCas9	negative selection	7143897
101294021	101294044	2	-	27260156	K562	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	-0.06521246555199788	[466]	[682,456,304,188]	-1	hSpCas9	negative selection	7208149
101288998	101289021	2	-	27260156	K562	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.7695080631097029	[316]	[892,429,423,229]	8	hSpCas9	negative selection	7208150
101308284	101308307	2	-	27260156	K562	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.7616822854928185	[1062]	[1239,1486,1911,1703]	8	hSpCas9	negative selection	7208151
101308159	101308182	2	+	27260156	HT29	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.17518691383837837	[764]	[809,739,868,856]	-4	hSpCas9	negative selection	7265146
101308447	101308470	2	-	27260156	HT29	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.038032078929088775	[771]	[854,1177,840,806]	-1	hSpCas9	negative selection	7265147
101294028	101294051	2	+	27260156	HT29	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.04596949419904123	[354]	[403,472,389,406]	-1	hSpCas9	negative selection	7265148
101294021	101294044	2	-	27260156	HT29	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.10550724539327803	[466]	[621,705,592,535]	2	hSpCas9	negative selection	7329400
101288998	101289021	2	-	27260156	HT29	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.10223174089134168	[316]	[367,362,376,329]	-2	hSpCas9	negative selection	7329401
101308284	101308307	2	-	27260156	HT29	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.35952953830995504	[1062]	[1556,1793,1610,1660]	7	hSpCas9	negative selection	7329402
101308159	101308182	2	+	27260156	MHHES1	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.11313828196241882	[764]	[927,822,878,602]	-2	hSpCas9	negative selection	7386397
101308447	101308470	2	-	27260156	MHHES1	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.011273884785990673	[771]	[1004,995,750,781]	0	hSpCas9	negative selection	7386398
101294028	101294051	2	+	27260156	MHHES1	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.0628097440134493	[354]	[473,387,271,507]	1	hSpCas9	negative selection	7386399
101294021	101294044	2	-	27260156	MHHES1	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.2430260770107534	[466]	[879,420,634,563]	4	hSpCas9	negative selection	7450651
101288998	101289021	2	-	27260156	MHHES1	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.24255270662604683	[316]	[461,291,521,400]	4	hSpCas9	negative selection	7450652
101308284	101308307	2	-	27260156	MHHES1	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.27292282032491033	[1062]	[1637,1677,1234,1284]	5	hSpCas9	negative selection	7450653
101308159	101308182	2	+	27260156	MEWO	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.16614612844549514	[764]	[675,596,647]	-4	hSpCas9	negative selection	7507648
101308447	101308470	2	-	27260156	MEWO	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.02383018356351696	[771]	[637,725,752]	0	hSpCas9	negative selection	7507649
101294028	101294051	2	+	27260156	MEWO	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.1604599427735724	[354]	[407,276,227]	-4	hSpCas9	negative selection	7507650
101294021	101294044	2	-	27260156	MEWO	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.0706336728675163	[466]	[646,426,338]	1	hSpCas9	negative selection	7571902
101288998	101289021	2	-	27260156	MEWO	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.45366480597771064	[316]	[194,305,143]	-7	hSpCas9	negative selection	7571903
101308284	101308307	2	-	27260156	MEWO	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	-0.022093128487345348	[1062]	[1134,793,1039]	0	hSpCas9	negative selection	7571904
101308159	101308182	2	+	27260156	LNCAPCLONEFGC	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.09699060796276704	[764]	[644,703,589,639]	-1	hSpCas9	negative selection	7628899
101308447	101308470	2	-	27260156	LNCAPCLONEFGC	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.052979271600816946	[771]	[543,624,904,661]	-1	hSpCas9	negative selection	7628900
101294028	101294051	2	+	27260156	LNCAPCLONEFGC	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.2501120357488906	[354]	[317,345,535,355]	4	hSpCas9	negative selection	7628901
101294021	101294044	2	-	27260156	LNCAPCLONEFGC	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.3624544376766268	[466]	[546,426,666,559]	6	hSpCas9	negative selection	7693153
101288998	101289021	2	-	27260156	LNCAPCLONEFGC	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.24147145079983373	[316]	[181,258,392,539]	4	hSpCas9	negative selection	7693154
101308284	101308307	2	-	27260156	LNCAPCLONEFGC	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.6735180423284077	[1062]	[1583,1247,1856,1518]	9	hSpCas9	negative selection	7693155
101308159	101308182	2	+	27260156	PANC0327	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.6661893128793545	[764]	[374,493,439,390]	-7	hSpCas9	negative selection	7750150
101308447	101308470	2	-	27260156	PANC0327	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.25832882900547016	[771]	[985,1191,511,555]	4	hSpCas9	negative selection	7750151
101294028	101294051	2	+	27260156	PANC0327	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.08350002582804833	[354]	[473,158,409,179]	-1	hSpCas9	negative selection	7750152
101294021	101294044	2	-	27260156	PANC0327	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.45653165628700587	[466]	[311,992,471,423]	6	hSpCas9	negative selection	7814404
101288998	101289021	2	-	27260156	PANC0327	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.2791481485020504	[316]	[453,487,244,169]	4	hSpCas9	negative selection	7814405
101308284	101308307	2	-	27260156	PANC0327	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.26031927178866154	[1062]	[1188,822,1147,1407]	4	hSpCas9	negative selection	7814406
101308159	101308182	2	+	27260156	NCIH2009	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.13628415550708417	[764]	[1135,1198,608]	-2	hSpCas9	negative selection	7871401
101308447	101308470	2	-	27260156	NCIH2009	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.1398718313732742	[771]	[1293,752,1544]	2	hSpCas9	negative selection	7871402
101294028	101294051	2	+	27260156	NCIH2009	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.296966745850991	[354]	[585,375,284]	-4	hSpCas9	negative selection	7871403
101294021	101294044	2	-	27260156	NCIH2009	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.20229628922778306	[466]	[863,815,591]	2	hSpCas9	negative selection	7935655
101288998	101289021	2	-	27260156	NCIH2009	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.2961606597219645	[316]	[502,514,604]	4	hSpCas9	negative selection	7935656
101308284	101308307	2	-	27260156	NCIH2009	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.6230606745861453	[1062]	[3097,2313,1605]	8	hSpCas9	negative selection	7935657
101308159	101308182	2	+	27260156	NCIH1373	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.663648770165269	[764]	[628,553,382,161]	-6	hSpCas9	negative selection	7992652
101308447	101308470	2	-	27260156	NCIH1373	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.5231193490444436	[771]	[847,540,434,165]	-5	hSpCas9	negative selection	7992653
101294028	101294051	2	+	27260156	NCIH1373	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.3863448657917635	[354]	[1455,345,218,54]	4	hSpCas9	negative selection	7992654
101294021	101294044	2	-	27260156	NCIH1373	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.3637459083823396	[466]	[581,471,750,237]	3	hSpCas9	negative selection	8056906
101288998	101289021	2	-	27260156	NCIH1373	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.39836550281355343	[316]	[328,426,429,178]	4	hSpCas9	negative selection	8056907
101308284	101308307	2	-	27260156	NCIH1373	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.9719998487126185	[1062]	[2905,1697,2027,762]	8	hSpCas9	negative selection	8056908
101308159	101308182	2	+	27260156	PATU8902	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.009835669381972334	[764]	[1072,1009,872,1350]	0	hSpCas9	negative selection	8113903
101308447	101308470	2	-	27260156	PATU8902	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.6102656965657904	[771]	[400,845,587,1052]	-5	hSpCas9	negative selection	8113904
101294028	101294051	2	+	27260156	PATU8902	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.6835368660621861	[354]	[438,397,202,201]	-6	hSpCas9	negative selection	8113905
101294021	101294044	2	-	27260156	PATU8902	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.02100121598412101	[466]	[683,740,437,851]	0	hSpCas9	negative selection	8178157
101288998	101289021	2	-	27260156	PATU8902	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.7979152850755307	[316]	[1113,910,291,879]	8	hSpCas9	negative selection	8178158
101308284	101308307	2	-	27260156	PATU8902	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	1.137690100727941	[1062]	[2661,3440,3213,3766]	9	hSpCas9	negative selection	8178159
101308159	101308182	2	+	27260156	PANC1	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.713347394888484	[764]	[445,439,430,302]	-7	hSpCas9	negative selection	8235154
101308447	101308470	2	-	27260156	PANC1	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.24000703729521744	[771]	[548,605,690,423]	-4	hSpCas9	negative selection	8235155
101294028	101294051	2	+	27260156	PANC1	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.37221577081731283	[354]	[283,438,610,271]	6	hSpCas9	negative selection	8235156
101294021	101294044	2	-	27260156	PANC1	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.23729148047241763	[466]	[337,879,400,367]	4	hSpCas9	negative selection	8299408
101288998	101289021	2	-	27260156	PANC1	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.17470138061676277	[316]	[298,307,326,292]	2	hSpCas9	negative selection	8299409
101308284	101308307	2	-	27260156	PANC1	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.183948545775235	[1062]	[1051,1364,1132,704]	3	hSpCas9	negative selection	8299410
101308159	101308182	2	+	27260156	PANC0813	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	0.10308300269958282	[764]	[1188,816,1087,795]	1	hSpCas9	negative selection	8356405
101308447	101308470	2	-	27260156	PANC0813	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.08259478829895628	[771]	[1046,970,868,959]	1	hSpCas9	negative selection	8356406
101294028	101294051	2	+	27260156	PANC0813	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.17251402871132043	[354]	[406,485,218,369]	-3	hSpCas9	negative selection	8356407
101294021	101294044	2	-	27260156	PANC0813	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.38352298148196545	[466]	[995,738,558,598]	6	hSpCas9	negative selection	8420659
101288998	101289021	2	-	27260156	PANC0813	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.10081074339312723	[316]	[512,249,370,273]	-2	hSpCas9	negative selection	8420660
101308284	101308307	2	-	27260156	PANC0813	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.5444775408612907	[1062]	[2092,1812,1878,1537]	8	hSpCas9	negative selection	8420661
101308159	101308182	2	+	27260156	RDES	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.16172451353595774	[764]	[751,661,903,832]	-3	hSpCas9	negative selection	8477656
101308447	101308470	2	-	27260156	RDES	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.1771830637681221	[771]	[621,752,921,877]	-3	hSpCas9	negative selection	8477657
101294028	101294051	2	+	27260156	RDES	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.011407024292344414	[354]	[308,390,386,598]	0	hSpCas9	negative selection	8477658
101294021	101294044	2	-	27260156	RDES	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.08630317548221224	[466]	[371,787,633,479]	1	hSpCas9	negative selection	8541910
101288998	101289021	2	-	27260156	RDES	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.20017191406899687	[316]	[362,400,324,612]	3	hSpCas9	negative selection	8541911
101308284	101308307	2	-	27260156	RDES	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.46076733674477666	[1062]	[1407,1705,1697,1965]	7	hSpCas9	negative selection	8541912
101308159	101308182	2	+	27260156	PC3	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.43263301903651563	[764]	[368,645,606,681]	-7	hSpCas9	negative selection	8598907
101308447	101308470	2	-	27260156	PC3	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.19474068084941087	[771]	[396,628,1265,690]	-4	hSpCas9	negative selection	8598908
101294028	101294051	2	+	27260156	PC3	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.06661232078564133	[354]	[227,305,460,422]	-1	hSpCas9	negative selection	8598909
101294021	101294044	2	-	27260156	PC3	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	-0.0404052514516889	[466]	[211,452,871,510]	-1	hSpCas9	negative selection	8663161
101288998	101289021	2	-	27260156	PC3	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.031062339338674527	[316]	[142,317,663,356]	0	hSpCas9	negative selection	8663162
101308284	101308307	2	-	27260156	PC3	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.16706223665127107	[1062]	[760,965,2542,1096]	4	hSpCas9	negative selection	8663163
101308159	101308182	2	+	27260156	PATU8988T	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.06356328840760372	[764]	[715,751,630,737]	-1	hSpCas9	negative selection	8720158
101308447	101308470	2	-	27260156	PATU8988T	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.46794040954352256	[771]	[525,641,391,614]	-6	hSpCas9	negative selection	8720159
101294028	101294051	2	+	27260156	PATU8988T	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.024631466198953733	[354]	[288,528,324,262]	0	hSpCas9	negative selection	8720160
101294021	101294044	2	-	27260156	PATU8988T	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	-0.43195833542822143	[466]	[362,454,228,300]	-6	hSpCas9	negative selection	8784412
101288998	101289021	2	-	27260156	PATU8988T	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.18597969577866114	[316]	[208,330,182,368]	-3	hSpCas9	negative selection	8784413
101308284	101308307	2	-	27260156	PATU8988T	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.31117921153783423	[1062]	[1044,1426,1261,1386]	5	hSpCas9	negative selection	8784414
101308159	101308182	2	+	27260156	T47D	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.23882367009375827	[764]	[621,794,889,705]	-5	hSpCas9	negative selection	8841409
101308447	101308470	2	-	27260156	T47D	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.02761375760349427	[771]	[1007,839,865,961]	0	hSpCas9	negative selection	8841410
101294028	101294051	2	+	27260156	T47D	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.15858043559258755	[354]	[377,326,351,430]	-4	hSpCas9	negative selection	8841411
101294021	101294044	2	-	27260156	T47D	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.060199140598118775	[466]	[639,478,495,665]	1	hSpCas9	negative selection	8905663
101288998	101289021	2	-	27260156	T47D	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.35416958053738357	[316]	[508,501,437,435]	7	hSpCas9	negative selection	8905664
101308284	101308307	2	-	27260156	T47D	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.2953812400207163	[1062]	[1566,1413,1440,1671]	6	hSpCas9	negative selection	8905665
101308159	101308182	2	+	27260156	SU8686	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	0.01347536341818334	[764]	[712,555,871,987]	0	hSpCas9	negative selection	8962660
101308447	101308470	2	-	27260156	SU8686	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.01717374158430729	[771]	[789,634,661,977]	0	hSpCas9	negative selection	8962661
101294028	101294051	2	+	27260156	SU8686	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.05201154596763219	[354]	[348,231,538,359]	0	hSpCas9	negative selection	8962662
101294021	101294044	2	-	27260156	SU8686	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.4533368246455977	[466]	[582,564,571,860]	7	hSpCas9	negative selection	9026914
101288998	101289021	2	-	27260156	SU8686	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.0335738908638511	[316]	[271,314,281,439]	0	hSpCas9	negative selection	9026915
101308284	101308307	2	-	27260156	SU8686	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.3119109764162873	[1062]	[1154,1271,1280,1580]	5	hSpCas9	negative selection	9026916
101308159	101308182	2	+	27260156	SKES1	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.2581870269081847	[764]	[663,779,608,526]	-5	hSpCas9	negative selection	9083911
101308447	101308470	2	-	27260156	SKES1	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.016439721943700136	[771]	[574,955,683,874]	0	hSpCas9	negative selection	9083912
101294028	101294051	2	+	27260156	SKES1	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.025793507596314047	[354]	[187,370,534,279]	0	hSpCas9	negative selection	9083913
101294021	101294044	2	-	27260156	SKES1	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.06936078833411381	[466]	[463,522,528,439]	1	hSpCas9	negative selection	9148165
101288998	101289021	2	-	27260156	SKES1	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.328857367765397	[316]	[283,350,235,160]	-6	hSpCas9	negative selection	9148166
101308284	101308307	2	-	27260156	SKES1	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.04423490132953645	[1062]	[1329,1047,1069,957]	1	hSpCas9	negative selection	9148167
101308159	101308182	2	+	27260156	TOV112D	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.19076727628072532	[764]	[638,1010,772,350]	-4	hSpCas9	negative selection	9205162
101308447	101308470	2	-	27260156	TOV112D	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.004716490858525879	[771]	[622,1083,628,808]	0	hSpCas9	negative selection	9205163
101294028	101294051	2	+	27260156	TOV112D	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	0.02392650903235244	[354]	[249,357,496,330]	0	hSpCas9	negative selection	9205164
101294021	101294044	2	-	27260156	TOV112D	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	-0.224013389376281	[466]	[432,512,480,209]	-4	hSpCas9	negative selection	9269416
101288998	101289021	2	-	27260156	TOV112D	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.237714192074924	[316]	[381,329,198,569]	4	hSpCas9	negative selection	9269417
101308284	101308307	2	-	27260156	TOV112D	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.22150257035745713	[1062]	[1207,1504,1276,1040]	4	hSpCas9	negative selection	9269418
101308159	101308182	2	+	27260156	TC71	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.2656605750745548	[764]	[593,816,606,716]	-6	hSpCas9	negative selection	9326413
101308447	101308470	2	-	27260156	TC71	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	-0.21408699761579708	[771]	[582,692,758,826]	-5	hSpCas9	negative selection	9326414
101294028	101294051	2	+	27260156	TC71	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.21423444772697403	[354]	[319,341,286,366]	-5	hSpCas9	negative selection	9326415
101294021	101294044	2	-	27260156	TC71	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.029246791957253583	[466]	[531,569,436,505]	0	hSpCas9	negative selection	9390667
101288998	101289021	2	-	27260156	TC71	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	-0.10657496271195399	[316]	[311,330,272,349]	-3	hSpCas9	negative selection	9390668
101308284	101308307	2	-	27260156	TC71	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.21248718473323125	[1062]	[1296,1069,1414,1507]	5	hSpCas9	negative selection	9390669
101308159	101308182	2	+	27260156	TC32	viability	CGTAGCGCTCCTCATTGTAGAGG	RNF149	ENSG00000163162	-0.07994529831752883	[764]	[666,601,767,686]	-1	hSpCas9	negative selection	9447664
101308447	101308470	2	-	27260156	TC32	viability	CGTGGTAAACATCGAGTACGTGG	RNF149	ENSG00000163162	0.1509191563971124	[771]	[812,740,921,732]	2	hSpCas9	negative selection	9447665
101294028	101294051	2	+	27260156	TC32	viability	TTACAGTATGAAGTAGAAGCTGG	RNF149	ENSG00000163162	-0.040658499684252725	[354]	[287,232,376,434]	0	hSpCas9	negative selection	9447666
101294021	101294044	2	-	27260156	TC32	viability	CTACTTCATACTGTAAAGCATGG	RNF149	ENSG00000163162	0.24128658338100398	[466]	[372,543,660,495]	4	hSpCas9	negative selection	9511918
101288998	101289021	2	-	27260156	TC32	viability	TATTGAAAATTTCAAAGTAAAGG	RNF149	ENSG00000163162	0.23381805861636912	[316]	[406,221,485,328]	4	hSpCas9	negative selection	9511919
101308284	101308307	2	-	27260156	TC32	viability	CGCTTCTTCGTGCCCGAGCCCGG	RNF149	ENSG00000163162	0.41292578285392323	[1062]	[1293,950,1636,1573]	7	hSpCas9	negative selection	9511920
101277226	101277249	2	+	27869803	HPAFII	viability after 27 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-1.3939490509136299	[328]	[85,48,NaN]	-7	hSpCas9	negative selection	9571018
101277271	101277294	2	-	27869803	HPAFII	viability after 27 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-0.8156441302621849	[13]	[7,0,NaN]	-5	hSpCas9	negative selection	9571019
101281906	101281929	2	+	27869803	HPAFII	viability after 27 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	2.756910066690569	[131]	[179,709,NaN]	9	hSpCas9	negative selection	9571020
101281978	101282001	2	+	27869803	HPAFII	viability after 27 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	-0.29919040747131875	[129]	[6,95,NaN]	-2	hSpCas9	negative selection	9571021
101308121	101308144	2	+	27869803	HPAFII	viability after 27 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-1.0390961016375264	[532]	[131,139,NaN]	-6	hSpCas9	negative selection	9571022
101308129	101308152	2	-	27869803	HPAFII	viability after 27 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	-0.23019546440049254	[386]	[119,217,NaN]	-2	hSpCas9	negative selection	9571023
101277226	101277249	2	+	27869803	HPAFII	viability after 15 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-1.043006373324968	[328]	[178,166,NaN]	-8	hSpCas9	negative selection	9653467
101277271	101277294	2	-	27869803	HPAFII	viability after 15 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	0.3887686410513749	[13]	[15,21,NaN]	4	hSpCas9	negative selection	9653468
101281906	101281929	2	+	27869803	HPAFII	viability after 15 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	1.9157268687612892	[131]	[287,688,NaN]	9	hSpCas9	negative selection	9653469
101281978	101282001	2	+	27869803	HPAFII	viability after 15 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	0.3638674191533906	[129]	[127,211,NaN]	4	hSpCas9	negative selection	9653470
101308121	101308144	2	+	27869803	HPAFII	viability after 15 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.8982447476037546	[532]	[442,222,NaN]	-7	hSpCas9	negative selection	9653471
101308129	101308152	2	-	27869803	HPAFII	viability after 15 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.24366577728947758	[386]	[653,391,NaN]	3	hSpCas9	negative selection	9653472
101277226	101277249	2	+	27869803	ASPC1	viability after 36 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	0.2819070230042729	[794]	[453,373,222]	3	hSpCas9	negative selection	9735916
101277271	101277294	2	-	27869803	ASPC1	viability after 36 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-2.005533122079495	[62]	[0,14,0]	-9	hSpCas9	negative selection	9735917
101281906	101281929	2	+	27869803	ASPC1	viability after 36 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	0.19155621115973825	[500]	[300,241,92]	2	hSpCas9	negative selection	9735918
101281978	101282001	2	+	27869803	ASPC1	viability after 36 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	-1.577179357447372	[242]	[20,14,43]	-8	hSpCas9	negative selection	9735919
101308121	101308144	2	+	27869803	ASPC1	viability after 36 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	0.3427001496912022	[1115]	[448,98,833]	3	hSpCas9	negative selection	9735920
101308129	101308152	2	-	27869803	ASPC1	viability after 36 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.5910998488319259	[1138]	[677,481,629]	6	hSpCas9	negative selection	9735921
101277226	101277249	2	+	27869803	PATU8988S	viability after 35 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	0.11171931443842831	[650]	[195,370,NaN]	1	hSpCas9	negative selection	9818365
101277271	101277294	2	-	27869803	PATU8988S	viability after 35 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-1.687957223926186	[31]	[3,3,NaN]	-8	hSpCas9	negative selection	9818366
101281906	101281929	2	+	27869803	PATU8988S	viability after 35 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	0.28368357301678115	[364]	[155,201,NaN]	3	hSpCas9	negative selection	9818367
101281978	101282001	2	+	27869803	PATU8988S	viability after 35 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	-0.5226142164488261	[245]	[54,82,NaN]	-5	hSpCas9	negative selection	9818368
101308121	101308144	2	+	27869803	PATU8988S	viability after 35 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	0.42806217538582547	[991]	[552,521,NaN]	5	hSpCas9	negative selection	9818369
101308129	101308152	2	-	27869803	PATU8988S	viability after 35 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.7724041859574269	[847]	[528,637,NaN]	8	hSpCas9	negative selection	9818370
101277226	101277249	2	+	27869803	PATU8988S	viability after 31 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	0.25135296212370317	[650]	[242,392,NaN]	3	hSpCas9	negative selection	9900814
101277271	101277294	2	-	27869803	PATU8988S	viability after 31 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-2.317337883334516	[31]	[2,1,NaN]	-9	hSpCas9	negative selection	9900815
101281906	101281929	2	+	27869803	PATU8988S	viability after 31 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	0.7001549846424627	[364]	[129,371,NaN]	7	hSpCas9	negative selection	9900816
101281978	101282001	2	+	27869803	PATU8988S	viability after 31 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	-0.7043122586875004	[245]	[68,48,NaN]	-6	hSpCas9	negative selection	9900817
101308121	101308144	2	+	27869803	PATU8988S	viability after 31 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	0.6037315466588317	[991]	[502,725,NaN]	7	hSpCas9	negative selection	9900818
101308129	101308152	2	-	27869803	PATU8988S	viability after 31 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.5604721357095064	[847]	[422,594,NaN]	6	hSpCas9	negative selection	9900819
101277226	101277249	2	+	27869803	HPAFII	viability after 35 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-1.518437248426035	[328]	[99,10,NaN]	-7	hSpCas9	negative selection	9983263
101277271	101277294	2	-	27869803	HPAFII	viability after 35 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	0.49723184835544476	[13]	[17,0,NaN]	3	hSpCas9	negative selection	9983264
101281906	101281929	2	+	27869803	HPAFII	viability after 35 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	2.4694611367643393	[131]	[93,680,NaN]	9	hSpCas9	negative selection	9983265
101281978	101282001	2	+	27869803	HPAFII	viability after 35 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	-0.9262283354031391	[129]	[4,67,NaN]	-5	hSpCas9	negative selection	9983266
101308121	101308144	2	+	27869803	HPAFII	viability after 35 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-0.5416272035829496	[532]	[103,276,NaN]	-3	hSpCas9	negative selection	9983267
101308129	101308152	2	-	27869803	HPAFII	viability after 35 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	-0.05899680538872487	[386]	[85,302,NaN]	0	hSpCas9	negative selection	9983268
101277226	101277249	2	+	27869803	HPAFII	viability after 31 days	TGGGCACGTGTGCTAGGAGATGG	RNF149	ENSG00000163162	-1.8624246714638195	[328]	[56,43,NaN]	-8	hSpCas9	negative selection	10065712
101277271	101277294	2	-	27869803	HPAFII	viability after 31 days	GCTCTCTTGCAGAAGCCGGCAGG	RNF149	ENSG00000163162	-1.6154267055042615	[13]	[3,0,NaN]	-7	hSpCas9	negative selection	10065713
101281906	101281929	2	+	27869803	HPAFII	viability after 31 days	CACTGTGGCTCAGATTCAGCAGG	RNF149	ENSG00000163162	2.6152758662413422	[131]	[105,832,NaN]	9	hSpCas9	negative selection	10065714
101281978	101282001	2	+	27869803	HPAFII	viability after 31 days	GCTAGACTCAAATTTGCAGCTGG	RNF149	ENSG00000163162	0.5411580931422866	[129]	[53,162,NaN]	4	hSpCas9	negative selection	10065715
101308121	101308144	2	+	27869803	HPAFII	viability after 31 days	CTGCTCACCCGCGTGAGACATGG	RNF149	ENSG00000163162	-1.0610067846197122	[532]	[106,182,NaN]	-6	hSpCas9	negative selection	10065716
101308129	101308152	2	-	27869803	HPAFII	viability after 31 days	CACCTTGCCCATGTCTCACGCGG	RNF149	ENSG00000163162	0.2146249286250539	[386]	[73,445,NaN]	1	hSpCas9	negative selection	10065717
101308577	101308600	2	-	28162770	P31FUJ	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	0.02753809225015208	[267]	[320]	0	hSpCas9	negative selection	10226205
101295079	101295102	2	-	28162770	P31FUJ	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.5813312502742874	[272]	[479]	6	hSpCas9	negative selection	10226206
101308319	101308342	2	+	28162770	P31FUJ	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	0.4862212190414714	[177]	[292]	5	hSpCas9	negative selection	10226207
101286127	101286150	2	+	28162770	P31FUJ	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	0.0597094024962489	[217]	[266]	0	hSpCas9	negative selection	10226208
101281993	101282016	2	+	28162770	P31FUJ	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-0.18454703580715748	[146]	[151]	-2	hSpCas9	negative selection	10226209
101308415	101308438	2	+	28162770	P31FUJ	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	0.5108580423258355	[42]	[71]	6	hSpCas9	negative selection	10226210
101308172	101308195	2	+	28162770	P31FUJ	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	0.7890021659039699	[196]	[399]	8	hSpCas9	negative selection	10226211
101281921	101281944	2	+	28162770	P31FUJ	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	0.046012784109993765	[393]	[477]	0	hSpCas9	negative selection	10226212
101308426	101308449	2	-	28162770	P31FUJ	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	-0.27394089920786513	[248]	[241]	-3	hSpCas9	negative selection	10226213
101308245	101308268	2	+	28162770	P31FUJ	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	0.9598428735280174	[55]	[127]	9	hSpCas9	negative selection	10226214
101308577	101308600	2	-	28162770	TF1	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	NaN	[NaN]	[217]	1	hSpCas9	negative selection	10395571
101295079	101295102	2	-	28162770	TF1	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	NaN	[NaN]	[500]	1	hSpCas9	negative selection	10395572
101308319	101308342	2	+	28162770	TF1	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10395573
101286127	101286150	2	+	28162770	TF1	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10395574
101281993	101282016	2	+	28162770	TF1	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10395575
101308415	101308438	2	+	28162770	TF1	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10395576
101308172	101308195	2	+	28162770	TF1	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	NaN	[NaN]	[222]	1	hSpCas9	negative selection	10395577
101281921	101281944	2	+	28162770	TF1	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	NaN	[NaN]	[171]	1	hSpCas9	negative selection	10395578
101308426	101308449	2	-	28162770	TF1	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	NaN	[NaN]	[393]	1	hSpCas9	negative selection	10395579
101308245	101308268	2	+	28162770	TF1	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10395580
101308577	101308600	2	-	28162770	SKM1	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	0.9447991256849639	[66]	[227]	8	hSpCas9	negative selection	10564937
101295079	101295102	2	-	28162770	SKM1	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.3206026974207949	[76]	[169]	3	hSpCas9	negative selection	10564938
101308319	101308342	2	+	28162770	SKM1	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	0.5851736834838679	[45]	[121]	5	hSpCas9	negative selection	10564939
101286127	101286150	2	+	28162770	SKM1	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	0.4003907233144425	[59]	[139]	4	hSpCas9	negative selection	10564940
101281993	101282016	2	+	28162770	SKM1	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	0.10760897408659653	[41]	[79]	1	hSpCas9	negative selection	10564941
101308415	101308438	2	+	28162770	SKM1	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	-1.117457581548177	[26]	[21]	-7	hSpCas9	negative selection	10564942
101308172	101308195	2	+	28162770	SKM1	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	-0.06527284903436947	[57]	[97]	0	hSpCas9	negative selection	10564943
101281921	101281944	2	+	28162770	SKM1	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	0.7483140267347492	[65]	[195]	7	hSpCas9	negative selection	10564944
101308426	101308449	2	-	28162770	SKM1	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	0.6506321025962744	[88]	[246]	6	hSpCas9	negative selection	10564945
101308245	101308268	2	+	28162770	SKM1	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	-1.2143191208007655	[20]	[15]	-7	hSpCas9	negative selection	10564946
101308577	101308600	2	-	28162770	SKM1	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	0.9447991256849639	[66]	[227]	8	hSpCas9	negative selection	10734303
101295079	101295102	2	-	28162770	SKM1	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.3206026974207949	[76]	[169]	3	hSpCas9	negative selection	10734304
101308319	101308342	2	+	28162770	SKM1	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	0.5851736834838679	[45]	[121]	5	hSpCas9	negative selection	10734305
101286127	101286150	2	+	28162770	SKM1	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	0.4003907233144425	[59]	[139]	4	hSpCas9	negative selection	10734306
101281993	101282016	2	+	28162770	SKM1	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	0.10760897408659653	[41]	[79]	1	hSpCas9	negative selection	10734307
101308415	101308438	2	+	28162770	SKM1	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	-1.117457581548177	[26]	[21]	-7	hSpCas9	negative selection	10734308
101308172	101308195	2	+	28162770	SKM1	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	-0.06527284903436947	[57]	[97]	0	hSpCas9	negative selection	10734309
101281921	101281944	2	+	28162770	SKM1	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	0.7483140267347492	[65]	[195]	7	hSpCas9	negative selection	10734310
101308426	101308449	2	-	28162770	SKM1	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	0.6506321025962744	[88]	[246]	6	hSpCas9	negative selection	10734311
101308245	101308268	2	+	28162770	SKM1	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	-1.2143191208007655	[20]	[15]	-7	hSpCas9	negative selection	10734312
101308577	101308600	2	-	28162770	PL21	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	1.0731004259001842	[260]	[238]	8	hSpCas9	negative selection	10903669
101295079	101295102	2	-	28162770	PL21	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.5251449129056913	[280]	[175]	4	hSpCas9	negative selection	10903670
101308319	101308342	2	+	28162770	PL21	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	0.4365798103114007	[145]	[85]	4	hSpCas9	negative selection	10903671
101286127	101286150	2	+	28162770	PL21	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	0.9522121010457346	[189]	[159]	7	hSpCas9	negative selection	10903672
101281993	101282016	2	+	28162770	PL21	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-1.3848228862318361	[167]	[27]	-7	hSpCas9	negative selection	10903673
101308415	101308438	2	+	28162770	PL21	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	1.2001396144893202	[78]	[78]	8	hSpCas9	negative selection	10903674
101308172	101308195	2	+	28162770	PL21	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	1.0806759478877486	[150]	[138]	8	hSpCas9	negative selection	10903675
101281921	101281944	2	+	28162770	PL21	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	0.15866297851316086	[246]	[119]	1	hSpCas9	negative selection	10903676
101308426	101308449	2	-	28162770	PL21	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	-0.16141555451875314	[202]	[78]	-1	hSpCas9	negative selection	10903677
101308245	101308268	2	+	28162770	PL21	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	2.245943304102445	[30]	[63]	9	hSpCas9	negative selection	10903678
101308577	101308600	2	-	28162770	P31FUJ	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	0.02753809225015208	[267]	[320]	0	hSpCas9	negative selection	11073035
101295079	101295102	2	-	28162770	P31FUJ	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.5813312502742874	[272]	[479]	6	hSpCas9	negative selection	11073036
101308319	101308342	2	+	28162770	P31FUJ	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	0.4862212190414714	[177]	[292]	5	hSpCas9	negative selection	11073037
101286127	101286150	2	+	28162770	P31FUJ	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	0.0597094024962489	[217]	[266]	0	hSpCas9	negative selection	11073038
101281993	101282016	2	+	28162770	P31FUJ	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-0.18454703580715748	[146]	[151]	-2	hSpCas9	negative selection	11073039
101308415	101308438	2	+	28162770	P31FUJ	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	0.5108580423258355	[42]	[71]	6	hSpCas9	negative selection	11073040
101308172	101308195	2	+	28162770	P31FUJ	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	0.7890021659039699	[196]	[399]	8	hSpCas9	negative selection	11073041
101281921	101281944	2	+	28162770	P31FUJ	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	0.046012784109993765	[393]	[477]	0	hSpCas9	negative selection	11073042
101308426	101308449	2	-	28162770	P31FUJ	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	-0.27394089920786513	[248]	[241]	-3	hSpCas9	negative selection	11073043
101308245	101308268	2	+	28162770	P31FUJ	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	0.9598428735280174	[55]	[127]	9	hSpCas9	negative selection	11073044
101308577	101308600	2	-	28162770	OCIAML5	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	0.3021043592637631	[132]	[295]	2	hSpCas9	negative selection	11242401
101295079	101295102	2	-	28162770	OCIAML5	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	1.3020044793774785	[121]	[542]	9	hSpCas9	negative selection	11242402
101308319	101308342	2	+	28162770	OCIAML5	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	0.25645788591417207	[95]	[206]	2	hSpCas9	negative selection	11242403
101286127	101286150	2	+	28162770	OCIAML5	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	0.24746910268691746	[111]	[239]	2	hSpCas9	negative selection	11242404
101281993	101282016	2	+	28162770	OCIAML5	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-1.1944587683110748	[70]	[55]	-6	hSpCas9	negative selection	11242405
101308415	101308438	2	+	28162770	OCIAML5	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	0.013003849049894267	[27]	[50]	0	hSpCas9	negative selection	11242406
101308172	101308195	2	+	28162770	OCIAML5	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	1.4399600383095033	[77]	[381]	9	hSpCas9	negative selection	11242407
101281921	101281944	2	+	28162770	OCIAML5	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	0.08129623610571252	[143]	[274]	0	hSpCas9	negative selection	11242408
101308426	101308449	2	-	28162770	OCIAML5	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	1.0354586998775905	[109]	[406]	8	hSpCas9	negative selection	11242409
101308245	101308268	2	+	28162770	OCIAML5	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	-1.8520665708639967	[19]	[9]	-7	hSpCas9	negative selection	11242410
101308577	101308600	2	-	28162770	EOL1	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	-0.16954139179978345	[490]	[229]	-1	hSpCas9	negative selection	11411767
101295079	101295102	2	-	28162770	EOL1	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	-0.5124387005419542	[286]	[105]	-4	hSpCas9	negative selection	11411768
101308319	101308342	2	+	28162770	EOL1	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	-0.24537722987177774	[323]	[143]	-2	hSpCas9	negative selection	11411769
101286127	101286150	2	+	28162770	EOL1	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	-0.5358696312123181	[365]	[132]	-4	hSpCas9	negative selection	11411770
101281993	101282016	2	+	28162770	EOL1	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-1.8828071504870696	[286]	[40]	-8	hSpCas9	negative selection	11411771
101308415	101308438	2	+	28162770	EOL1	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	0.4830380609304996	[109]	[80]	4	hSpCas9	negative selection	11411772
101308172	101308195	2	+	28162770	EOL1	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	1.5378245538861046	[184]	[282]	9	hSpCas9	negative selection	11411773
101281921	101281944	2	+	28162770	EOL1	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	-0.1653943537422639	[363]	[170]	-1	hSpCas9	negative selection	11411774
101308426	101308449	2	-	28162770	EOL1	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	-0.23388159103394845	[249]	[111]	-2	hSpCas9	negative selection	11411775
101308245	101308268	2	+	28162770	EOL1	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	-2.8033726829926646	[52]	[3]	-9	hSpCas9	negative selection	11411776
101308577	101308600	2	-	28162770	MOLM13	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	1.1737954948539422	[384]	[627]	8	hSpCas9	negative selection	11581133
101295079	101295102	2	-	28162770	MOLM13	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.6368183905131672	[321]	[361]	5	hSpCas9	negative selection	11581134
101308319	101308342	2	+	28162770	MOLM13	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	0.0011897624432423148	[198]	[143]	0	hSpCas9	negative selection	11581135
101286127	101286150	2	+	28162770	MOLM13	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	1.6344285681475093	[236]	[531]	9	hSpCas9	negative selection	11581136
101281993	101282016	2	+	28162770	MOLM13	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-0.6859159545344565	[177]	[79]	-4	hSpCas9	negative selection	11581137
101308415	101308438	2	+	28162770	MOLM13	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	-0.06816351869563109	[57]	[39]	0	hSpCas9	negative selection	11581138
101308172	101308195	2	+	28162770	MOLM13	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	0.8922406319630523	[192]	[258]	6	hSpCas9	negative selection	11581139
101281921	101281944	2	+	28162770	MOLM13	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	0.08937775829084899	[311]	[239]	0	hSpCas9	negative selection	11581140
101308426	101308449	2	-	28162770	MOLM13	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	0.9785045408056537	[291]	[415]	7	hSpCas9	negative selection	11581141
101308245	101308268	2	+	28162770	MOLM13	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	-0.687388843933332	[48]	[21]	-4	hSpCas9	negative selection	11581142
101308577	101308600	2	-	28162770	HEL	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	0.7527923774652707	[327]	[353]	6	hSpCas9	negative selection	11750499
101295079	101295102	2	-	28162770	HEL	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	-0.025341301455119647	[258]	[162]	0	hSpCas9	negative selection	11750500
101308319	101308342	2	+	28162770	HEL	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	1.4403307851180636	[232]	[404]	9	hSpCas9	negative selection	11750501
101286127	101286150	2	+	28162770	HEL	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	0.5411406919925502	[249]	[232]	4	hSpCas9	negative selection	11750502
101281993	101282016	2	+	28162770	HEL	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-1.5648565874080103	[193]	[41]	-7	hSpCas9	negative selection	11750503
101308415	101308438	2	+	28162770	HEL	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	-1.1286367929516805	[98]	[28]	-6	hSpCas9	negative selection	11750504
101308172	101308195	2	+	28162770	HEL	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	1.019043936790486	[150]	[195]	8	hSpCas9	negative selection	11750505
101281921	101281944	2	+	28162770	HEL	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	-0.43180812136469704	[277]	[131]	-3	hSpCas9	negative selection	11750506
101308426	101308449	2	-	28162770	HEL	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	0.144619591226958	[273]	[193]	1	hSpCas9	negative selection	11750507
101308245	101308268	2	+	28162770	HEL	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	0.6157717844000876	[53]	[52]	5	hSpCas9	negative selection	11750508
101308577	101308600	2	-	28162770	MV411	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	0.9478772689238674	[279]	[454]	8	hSpCas9	negative selection	11919865
101295079	101295102	2	-	28162770	MV411	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.4983991243159941	[199]	[237]	4	hSpCas9	negative selection	11919866
101308319	101308342	2	+	28162770	MV411	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	0.20276850144904712	[163]	[158]	1	hSpCas9	negative selection	11919867
101286127	101286150	2	+	28162770	MV411	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	0.39231118016972033	[141]	[156]	3	hSpCas9	negative selection	11919868
101281993	101282016	2	+	28162770	MV411	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	0.2619371204778904	[98]	[99]	2	hSpCas9	negative selection	11919869
101308415	101308438	2	+	28162770	MV411	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	-0.8900659729671596	[32]	[14]	-6	hSpCas9	negative selection	11919870
101308172	101308195	2	+	28162770	MV411	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	1.2804526080107381	[107]	[220]	9	hSpCas9	negative selection	11919871
101281921	101281944	2	+	28162770	MV411	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	-0.1316803742411257	[237]	[182]	-1	hSpCas9	negative selection	11919872
101308426	101308449	2	-	28162770	MV411	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	0.26492497751161653	[163]	[165]	2	hSpCas9	negative selection	11919873
101308245	101308268	2	+	28162770	MV411	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	0.32687201827718004	[52]	[55]	3	hSpCas9	negative selection	11919874
101308577	101308600	2	-	28162770	MONOMAC1	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	-0.6267211223027989	[197]	[146]	-5	hSpCas9	negative selection	12089231
101295079	101295102	2	-	28162770	MONOMAC1	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	-0.0031571134655186406	[145]	[166]	0	hSpCas9	negative selection	12089232
101308319	101308342	2	+	28162770	MONOMAC1	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	-0.6995371875887371	[118]	[83]	-5	hSpCas9	negative selection	12089233
101286127	101286150	2	+	28162770	MONOMAC1	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	-0.43001401903716774	[113]	[96]	-4	hSpCas9	negative selection	12089234
101281993	101282016	2	+	28162770	MONOMAC1	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-0.5463710992875679	[92]	[72]	-4	hSpCas9	negative selection	12089235
101308415	101308438	2	+	28162770	MONOMAC1	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	1.659598977769269	[36]	[133]	9	hSpCas9	negative selection	12089236
101308172	101308195	2	+	28162770	MONOMAC1	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	-0.06524697450401247	[114]	[125]	0	hSpCas9	negative selection	12089237
101281921	101281944	2	+	28162770	MONOMAC1	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	-0.7819993477807098	[143]	[95]	-6	hSpCas9	negative selection	12089238
101308426	101308449	2	-	28162770	MONOMAC1	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	0.5166589677838053	[99]	[163]	5	hSpCas9	negative selection	12089239
101308245	101308268	2	+	28162770	MONOMAC1	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	-1.3225677291434126	[23]	[10]	-7	hSpCas9	negative selection	12089240
101308577	101308600	2	-	28162770	OCIAML2	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	-0.31932050196719586	[51]	[230]	-3	hSpCas9	negative selection	12258597
101295079	101295102	2	-	28162770	OCIAML2	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.4845159389735785	[48]	[379]	5	hSpCas9	negative selection	12258598
101308319	101308342	2	+	28162770	OCIAML2	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	0.3856346972963891	[28]	[209]	4	hSpCas9	negative selection	12258599
101286127	101286150	2	+	28162770	OCIAML2	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	0.5180548615300047	[31]	[253]	5	hSpCas9	negative selection	12258600
101281993	101282016	2	+	28162770	OCIAML2	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-1.4420606730453902	[24]	[50]	-7	hSpCas9	negative selection	12258601
101308415	101308438	2	+	28162770	OCIAML2	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	0.38735116988541085	[11]	[86]	4	hSpCas9	negative selection	12258602
101308172	101308195	2	+	28162770	OCIAML2	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	-0.08980804130123021	[23]	[124]	0	hSpCas9	negative selection	12258603
101281921	101281944	2	+	28162770	OCIAML2	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	-0.38505409353608727	[44]	[190]	-3	hSpCas9	negative selection	12258604
101308426	101308449	2	-	28162770	OCIAML2	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	0.008538011456398181	[32]	[183]	0	hSpCas9	negative selection	12258605
101308245	101308268	2	+	28162770	OCIAML2	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	-1.3551526078222254	[11]	[25]	-7	hSpCas9	negative selection	12258606
101308577	101308600	2	-	28162770	OCIAML3	viability	GCGGTGCTGCCATGGCGTGGCGG	RNF149	ENSG00000163162	-0.15790852551748977	[67]	[183]	-1	hSpCas9	negative selection	12427963
101295079	101295102	2	-	28162770	OCIAML3	viability	GTAACGATGACCATAGGGGTTGG	RNF149	ENSG00000163162	0.7238507902541522	[70]	[353]	6	hSpCas9	negative selection	12427964
101308319	101308342	2	+	28162770	OCIAML3	viability	GCAGCCCTCGAGGTCTCCGCCGG	RNF149	ENSG00000163162	-0.13457602168686578	[31]	[87]	-1	hSpCas9	negative selection	12427965
101286127	101286150	2	+	28162770	OCIAML3	viability	GTTCGGTGATCCAAAAGCCATGG	RNF149	ENSG00000163162	0.699983578060076	[72]	[357]	6	hSpCas9	negative selection	12427966
101281993	101282016	2	+	28162770	OCIAML3	viability	GCAGCTGGATCCCTTCCAGGAGG	RNF149	ENSG00000163162	-0.5796523473470931	[49]	[100]	-4	hSpCas9	negative selection	12427967
101308415	101308438	2	+	28162770	OCIAML3	viability	GACGCTCCACACCGTCAGGTTGG	RNF149	ENSG00000163162	-0.009045139603007124	[15]	[47]	0	hSpCas9	negative selection	12427968
101308172	101308195	2	+	28162770	OCIAML3	viability	ATTGTAGAGGACGACGGCCGAGG	RNF149	ENSG00000163162	-0.4720171159455526	[33]	[73]	-4	hSpCas9	negative selection	12427969
101281921	101281944	2	+	28162770	OCIAML3	viability	TCAGCAGGGGAGGCTGATGGTGG	RNF149	ENSG00000163162	0.8534513366470582	[76]	[419]	7	hSpCas9	negative selection	12427970
101308426	101308449	2	-	28162770	OCIAML3	viability	GGACCCGCAGACCAACCTGACGG	RNF149	ENSG00000163162	0.24729461365677866	[59]	[214]	2	hSpCas9	negative selection	12427971
101308245	101308268	2	+	28162770	OCIAML3	viability	CGAGCCACCAGGGCGACCCAGGG	RNF149	ENSG00000163162	0.21334728173344075	[9]	[34]	2	hSpCas9	negative selection	12427972