Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 51255
• Symbol: RNF181
• Description: ring finger protein 181

DataSource: http://genomecrispr.dkfz.de/#!/results/RNF181

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
85595817	85595840	2	+	26472758	Jiyoye	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	0.8981617340180157	[73]	[103]	6	hSpCas9	negative selection	138171
85596585	85596608	2	+	26472758	Jiyoye	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.9158719879989625	[122]	[174]	6	hSpCas9	negative selection	138172
85596838	85596861	2	+	26472758	Jiyoye	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	-0.7211487154696659	[657]	[300]	-5	hSpCas9	negative selection	138173
85596881	85596904	2	-	26472758	Jiyoye	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	0.6702097873396673	[59]	[71]	5	hSpCas9	negative selection	138174
85596602	85596625	2	+	26472758	Jiyoye	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	0.7856870047596033	[199]	[259]	5	hSpCas9	negative selection	138175
85596870	85596893	2	-	26472758	Jiyoye	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	1.7345373624438638	[105]	[265]	8	hSpCas9	negative selection	138176
85596917	85596940	2	-	26472758	Jiyoye	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.41773791193603527	[247]	[139]	-3	hSpCas9	negative selection	138177
85595781	85595804	2	+	26472758	Jiyoye	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	-0.6885836012995573	[108]	[50]	-5	hSpCas9	negative selection	138178
85595793	85595816	2	+	26472758	Jiyoye	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	-0.9898955712435216	[265]	[100]	-6	hSpCas9	negative selection	138179
85595825	85595848	2	-	26472758	Jiyoye	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	-1.3567572602606022	[179]	[52]	-7	hSpCas9	negative selection	138180
85595817	85595840	2	+	26472758	KBM7	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	1.1278159766814133	[288,440]	[434,339]	9	hSpCas9	negative selection	329289
85596585	85596608	2	+	26472758	KBM7	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.5782392321300779	[713,954]	[477,703]	6	hSpCas9	negative selection	329290
85596838	85596861	2	+	26472758	KBM7	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	-0.3326376068953427	[1950,1469]	[602,658]	-3	hSpCas9	negative selection	329291
85596881	85596904	2	-	26472758	KBM7	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	0.5008584733061738	[376,180]	[172,185]	5	hSpCas9	negative selection	329292
85596602	85596625	2	+	26472758	KBM7	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	0.05215178054599068	[983,571]	[420,325]	0	hSpCas9	negative selection	329293
85596870	85596893	2	-	26472758	KBM7	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	0.2823768269276856	[1086,1063]	[544,681]	3	hSpCas9	negative selection	329294
85596917	85596940	2	-	26472758	KBM7	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.04908956706038303	[1374,1257]	[826,473]	0	hSpCas9	negative selection	329295
85595781	85595804	2	+	26472758	KBM7	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	-0.2320283803182962	[399,255]	[128,128]	-2	hSpCas9	negative selection	329296
85595793	85595816	2	+	26472758	KBM7	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	-0.5609443283434539	[899,880]	[201,358]	-5	hSpCas9	negative selection	329297
85595825	85595848	2	-	26472758	KBM7	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	0.2868472935515709	[550,540]	[296,329]	3	hSpCas9	negative selection	329298
85595817	85595840	2	+	26472758	Raji	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	1.4069438172325075	[116]	[71]	9	hSpCas9	negative selection	520407
85596585	85596608	2	+	26472758	Raji	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.06473919796510574	[411]	[99]	0	hSpCas9	negative selection	520408
85596838	85596861	2	+	26472758	Raji	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	0.09186126325954724	[840]	[207]	0	hSpCas9	negative selection	520409
85596881	85596904	2	-	26472758	Raji	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	1.2190288912025085	[86]	[46]	9	hSpCas9	negative selection	520410
85596602	85596625	2	+	26472758	Raji	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	1.042811534077516	[296]	[141]	8	hSpCas9	negative selection	520411
85596870	85596893	2	-	26472758	Raji	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	0.18723684306281418	[491]	[129]	1	hSpCas9	negative selection	520412
85596917	85596940	2	-	26472758	Raji	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.02249463778708627	[559]	[131]	0	hSpCas9	negative selection	520413
85595781	85595804	2	+	26472758	Raji	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	-0.10561018796059884	[203]	[43]	-1	hSpCas9	negative selection	520414
85595793	85595816	2	+	26472758	Raji	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	-0.4251115454534212	[323]	[55]	-3	hSpCas9	negative selection	520415
85595825	85595848	2	-	26472758	Raji	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	-0.13118881301828283	[268]	[56]	-1	hSpCas9	negative selection	520416
85595817	85595840	2	+	26472758	K562	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	0.5478827596502127	[345]	[426]	4	hSpCas9	negative selection	711525
85596585	85596608	2	+	26472758	K562	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.06577053076414952	[764]	[616]	0	hSpCas9	negative selection	711526
85596838	85596861	2	+	26472758	K562	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	-0.1411202616982885	[1419]	[1086]	-1	hSpCas9	negative selection	711527
85596881	85596904	2	-	26472758	K562	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	1.3584904943752418	[157]	[341]	9	hSpCas9	negative selection	711528
85596602	85596625	2	+	26472758	K562	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	0.03483137596441355	[672]	[581]	0	hSpCas9	negative selection	711529
85596870	85596893	2	-	26472758	K562	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	-0.2588896190674972	[892]	[629]	-2	hSpCas9	negative selection	711530
85596917	85596940	2	-	26472758	K562	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.48728242362065477	[1002]	[603]	-3	hSpCas9	negative selection	711531
85595781	85595804	2	+	26472758	K562	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	-2.6168750015019606	[217]	[29]	-8	hSpCas9	negative selection	711532
85595793	85595816	2	+	26472758	K562	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	-0.157168816398566	[604]	[457]	-1	hSpCas9	negative selection	711533
85595825	85595848	2	-	26472758	K562	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	1.1067642865000984	[477]	[868]	8	hSpCas9	negative selection	711534
85596917	85596940	2	-	26627737	DLD1	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.32631241927357424	[543]	[196,320,137]	3	hSpCas9	negative selection	812929
85596917	85596940	2	-	26627737	GBM cells	viability after 5 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.39002239439086545	[280]	[125,103]	-6	hSpCas9	negative selection	895244
85596917	85596940	2	-	26627737	GBM cells	viability after 13 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.5716017131158915	[280]	[106,98]	-6	hSpCas9	negative selection	977559
85596917	85596940	2	-	26627737	GBM cells	viability after 21 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.08093230659969902	[280]	[159,129]	0	hSpCas9	negative selection	1059874
85596917	85596940	2	-	26627737	RPE1	viability after 9 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.12145250066021518	[887]	[294,311]	0	hSpCas9	negative selection	1142189
85596917	85596940	2	-	26627737	RPE1	viability after 12 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.41962492995073447	[887]	[305,332]	3	hSpCas9	negative selection	1224504
85596917	85596940	2	-	26627737	RPE1	viability after 15 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.10515063520383722	[887]	[146,316]	0	hSpCas9	negative selection	1306819
85596917	85596940	2	-	26627737	RPE1	viability after 18 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.12877977956140402	[887]	[349,167]	0	hSpCas9	negative selection	1389134
85596917	85596940	2	-	26627737	HeLa	viability after 8 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-1.1575784532468298	[484]	[98,138,49]	-8	hSpCas9	negative selection	1471449
85596917	85596940	2	-	26627737	HeLa	viability after 12 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.6743828402264593	[484]	[183,63,136]	-6	hSpCas9	negative selection	1553764
85596917	85596940	2	-	26627737	HeLa	viability after 15 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.8980594680924965	[484]	[112,107,95]	-7	hSpCas9	negative selection	1636079
85596917	85596940	2	-	26627737	HeLa	viability after 18 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.9447337231675024	[484]	[71,85,95]	-7	hSpCas9	negative selection	1718394
85596917	85596940	2	-	26627737	HCT116	viability after 6 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.6595305635392419	[482]	[224,61]	3	hSpCas9	negative selection	1800709
85596917	85596940	2	-	26627737	HCT116	viability after 8 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.03808152897022013	[262]	[113,171,136]	0	hSpCas9	negative selection	1883024
85596917	85596940	2	-	26627737	HCT116	viability after 9 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	1.1546059648328049	[482]	[161,385]	7	hSpCas9	negative selection	1965339
85596917	85596940	2	-	26627737	HCT116	viability after 12 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.30444073145453093	[262]	[111,161,242]	3	hSpCas9	negative selection	2047654
85596917	85596940	2	-	26627737	HCT116	viability after 15 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.20385809711272745	[262]	[98,117,171]	-2	hSpCas9	negative selection	2129969
85596917	85596940	2	-	26627737	HCT116	viability after 18 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.22209050038065137	[262]	[57,112,157]	-2	hSpCas9	negative selection	2212284
85595771	85595794	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGTCGTGTTCATCGAAATAGG	RNF181	ENSG00000168894	0.19102536762428096	[3,3]	[3,3]	4	hSpCas9	positive selection	3017252
85596534	85596557	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATGGACTTTGAAGACTTGGGG	RNF181	ENSG00000168894	0.2286001802035575	[3,3]	[3,3]	5	hSpCas9	positive selection	3017253
85595797	85595820	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCTCCTGCTCAGGGTCCGACGG	RNF181	ENSG00000168894	-0.26816332865695314	[1,1]	[1,0]	-4	hSpCas9	positive selection	3017254
85595782	85595805	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	0.29768509703972296	[2,2]	[3,2]	6	hSpCas9	positive selection	3017255
85595771	85595794	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGTCGTGTTCATCGAAATAGG	RNF181	ENSG00000168894	-0.7799105918982281	[3,3]	[2,0]	-9	hSpCas9	positive selection	3085110
85596534	85596557	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATGGACTTTGAAGACTTGGGG	RNF181	ENSG00000168894	-0.3427349136493278	[3,3]	[2,1]	-5	hSpCas9	positive selection	3085111
85595797	85595820	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCTCCTGCTCAGGGTCCGACGG	RNF181	ENSG00000168894	-0.456409605119509	[1,1]	[0,0]	-6	hSpCas9	positive selection	3085112
85595782	85595805	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	-0.347382692612048	[2,2]	[0,0]	-5	hSpCas9	positive selection	3085113
85596918	85596941		-	24336571	A375	resistance to PLX after 7 days	AAGCAGTACCTTGCTTAGCCAGG	RNF181	ENSG00000168894	0.2798138017828449	[8,8]	[10,10]	7	hSpCas9	positive selection	3141316
85596834	85596857		-	24336571	A375	resistance to PLX after 7 days	CTCAAATTCCAAAAGACACACGG	RNF181	ENSG00000168894	-0.13606478479778716	[7,7]	[7,6]	-4	hSpCas9	positive selection	3141317
85596892	85596915		-	24336571	A375	resistance to PLX after 7 days	GAATGCAGCTGGAATGGAAAAGG	RNF181	ENSG00000168894	-0.06433227991589385	[5,3]	[5,3]	-2	hSpCas9	positive selection	3141318
85596585	85596608		+	24336571	A375	resistance to PLX after 7 days	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.002677771266167195	[15,16]	[15,16]	0	hSpCas9	positive selection	3141319
85596512	85596535		+	24336571	A375	resistance to PLX after 7 days	TCCCCAGGTCACTTTTCAATAGG	RNF181	ENSG00000168894	0.05931568088910533	[9,8]	[8,10]	2	hSpCas9	positive selection	3141321
85596918	85596941		-	24336571	A375	resistance to PLX after 14 days	AAGCAGTACCTTGCTTAGCCAGG	RNF181	ENSG00000168894	0.9950531698913065	[8,9]	[7,9]	7	hSpCas9	positive selection	3199109
85596834	85596857		-	24336571	A375	resistance to PLX after 14 days	CTCAAATTCCAAAAGACACACGG	RNF181	ENSG00000168894	0.13839076547407858	[6,7]	[3,3]	1	hSpCas9	positive selection	3199110
85596892	85596915		-	24336571	A375	resistance to PLX after 14 days	GAATGCAGCTGGAATGGAAAAGG	RNF181	ENSG00000168894	-0.2253348587710693	[4,3]	[1,1]	-2	hSpCas9	positive selection	3199111
85596585	85596608		+	24336571	A375	resistance to PLX after 14 days	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.5804417723263036	[15,20]	[4,5]	-7	hSpCas9	positive selection	3199112
85596512	85596535		+	24336571	A375	resistance to PLX after 14 days	TCCCCAGGTCACTTTTCAATAGG	RNF181	ENSG00000168894	-0.3578642780207826	[9,10]	[2,3]	-4	hSpCas9	positive selection	3199114
85596918	85596941		-	24336571	A375	viability after 7 days	AAGCAGTACCTTGCTTAGCCAGG	RNF181	ENSG00000168894	-0.2908838317075265	[10]	[8,8]	-4	hSpCas9	negative selection	3256902
85596834	85596857		-	24336571	A375	viability after 7 days	CTCAAATTCCAAAAGACACACGG	RNF181	ENSG00000168894	-1.0061275083944272	[17]	[7,7]	-9	hSpCas9	negative selection	3256903
85596892	85596915		-	24336571	A375	viability after 7 days	GAATGCAGCTGGAATGGAAAAGG	RNF181	ENSG00000168894	-0.0921287508440467	[5]	[5,3]	-1	hSpCas9	negative selection	3256904
85596585	85596608		+	24336571	A375	viability after 7 days	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.407111778232107	[12]	[15,16]	6	hSpCas9	negative selection	3256905
85596512	85596535		+	24336571	A375	viability after 7 days	TCCCCAGGTCACTTTTCAATAGG	RNF181	ENSG00000168894	0.10733093596691523	[8]	[9,8]	1	hSpCas9	negative selection	3256907
85596918	85596941		-	24336571	A375	viability after 14 days	AAGCAGTACCTTGCTTAGCCAGG	RNF181	ENSG00000168894	-0.14451790044084795	[10]	[8,9]	-2	hSpCas9	negative selection	3314695
85596834	85596857		-	24336571	A375	viability after 14 days	CTCAAATTCCAAAAGACACACGG	RNF181	ENSG00000168894	-1.1050814317598874	[17]	[6,7]	-8	hSpCas9	negative selection	3314696
85596892	85596915		-	24336571	A375	viability after 14 days	GAATGCAGCTGGAATGGAAAAGG	RNF181	ENSG00000168894	-0.21330379033651137	[5]	[4,3]	-3	hSpCas9	negative selection	3314697
85596585	85596608		+	24336571	A375	viability after 14 days	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.5449712440502711	[12]	[15,20]	7	hSpCas9	negative selection	3314698
85596512	85596535		+	24336571	A375	viability after 14 days	TCCCCAGGTCACTTTTCAATAGG	RNF181	ENSG00000168894	0.28834505467819405	[8]	[9,10]	4	hSpCas9	negative selection	3314700
85597111	85597134	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	2.00939869800225	[37,37]	[0,0]	7	hSpCas9	positive selection	3390148
85596585	85596608	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.2184072195205627	[177,177]	[0,0]	-1	hSpCas9	positive selection	3390149
85597453	85597476	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.4499712893882311	[111,111]	[0,0]	2	hSpCas9	positive selection	3390150
85595771	85595794	2	-	26780180	HT29	viability (Avana library 4 designs)	GCAGTCGTGTTCATCGAAATAGG	RNF181	ENSG00000168894	2.33274313408151	[]	[]	8	hSpCas9	negative selection	3455627
85596533	85596556	2	+	26780180	HT29	viability (Avana library 4 designs)	GGATGGACTTTGAAGACTTGGGG	RNF181	ENSG00000168894	1.4714263191218	[]	[]	6	hSpCas9	negative selection	3455628
85595797	85595820	2	-	26780180	HT29	viability (Avana library 4 designs)	GTCTCCTGCTCAGGGTCCGACGG	RNF181	ENSG00000168894	1.18665171471543	[]	[]	4	hSpCas9	negative selection	3455629
85595781	85595804	2	+	26780180	HT29	viability (Avana library 4 designs)	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	2.26064326561183	[]	[]	7	hSpCas9	negative selection	3455630
85596533	85596556	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGGACTTTGAAGACTTGGGG	RNF181	ENSG00000168894	-1.02546428925721	[]	[]	-1	hSpCas9	negative selection	3553707
85595771	85595794	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGTCGTGTTCATCGAAATAGG	RNF181	ENSG00000168894	2.02301099641523	[]	[]	3	hSpCas9	negative selection	3553708
85595797	85595820	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTCTCCTGCTCAGGGTCCGACGG	RNF181	ENSG00000168894	3.2063604431062	[]	[]	5	hSpCas9	negative selection	3553709
85595781	85595804	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	4.52999444805631	[]	[]	7	hSpCas9	negative selection	3553710
85596585	85596608	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	3.5441665965913	[]	[]	5	hSpCas9	negative selection	3553711
85596537	85596560	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-1.23351028511252	[]	[]	-1	hSpCas9	negative selection	3553712
85596533	85596556	2	+	26780180	A375	viability (Avana lentiGuide)	GGATGGACTTTGAAGACTTGGGG	RNF181	ENSG00000168894	4.10117619151128	[]	[]	4	hSpCas9	negative selection	3662366
85595771	85595794	2	-	26780180	A375	viability (Avana lentiGuide)	GCAGTCGTGTTCATCGAAATAGG	RNF181	ENSG00000168894	1.55200999788235	[]	[]	1	hSpCas9	negative selection	3662367
85595797	85595820	2	-	26780180	A375	viability (Avana lentiGuide)	GTCTCCTGCTCAGGGTCCGACGG	RNF181	ENSG00000168894	12.4342759971284	[]	[]	7	hSpCas9	negative selection	3662368
85595781	85595804	2	+	26780180	A375	viability (Avana lentiGuide)	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	10.4714493872689	[]	[]	7	hSpCas9	negative selection	3662369
85596585	85596608	2	+	26780180	A375	viability (Avana lentiGuide)	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	11.6515001235053	[]	[]	7	hSpCas9	negative selection	3662370
85596537	85596560	2	+	26780180	A375	viability (Avana lentiGuide)	GGACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	20.6081252924089	[]	[]	8	hSpCas9	negative selection	3662371
85596533	85596556	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGGACTTTGAAGACTTGGGG	RNF181	ENSG00000168894	-0.33752022374260493	[5]	[4,3]	-5	hSpCas9	positive selection	3770973
85595771	85595794	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGTCGTGTTCATCGAAATAGG	RNF181	ENSG00000168894	-0.018646476445598414	[4]	[4,3]	0	hSpCas9	positive selection	3770974
85595797	85595820	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCTCCTGCTCAGGGTCCGACGG	RNF181	ENSG00000168894	0.07457163721014612	[3]	[3,4]	2	hSpCas9	positive selection	3770975
85595781	85595804	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	0.2054396348227983	[4]	[5,4]	6	hSpCas9	positive selection	3770976
85596585	85596608	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.28989167592043535	[4]	[5,5]	8	hSpCas9	positive selection	3770977
85596537	85596560	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-0.20156188257017854	[4]	[2,4]	-3	hSpCas9	positive selection	3770978
85596533	85596556	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGGACTTTGAAGACTTGGGG	RNF181	ENSG00000168894	-0.03653168310447973	[5]	[4,4]	0	hSpCas9	positive selection	3879580
85595771	85595794	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGTCGTGTTCATCGAAATAGG	RNF181	ENSG00000168894	-0.8471593208383331	[5]	[2,1]	-8	hSpCas9	positive selection	3879581
85595797	85595820	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCTCCTGCTCAGGGTCCGACGG	RNF181	ENSG00000168894	-0.4339233361923687	[3]	[0,3]	-5	hSpCas9	positive selection	3879582
85595781	85595804	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	-0.3100443349648279	[4]	[2,3]	-4	hSpCas9	positive selection	3879583
85596585	85596608	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.05996867022486185	[4]	[3,4]	-1	hSpCas9	positive selection	3879584
85596537	85596560	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-0.4803818992092941	[5]	[4,1]	-6	hSpCas9	positive selection	3879585
85597453	85597476	2	+	26780180	A375	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.657582475117312	[]	[]	2	hSpCas9	negative selection	3989695
85596826	85596849	2	+	26780180	A375	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.205489581139708	[]	[]	0	hSpCas9	negative selection	3989696
85597138	85597161	2	-	26780180	A375	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	1.30639860224591	[]	[]	7	hSpCas9	negative selection	3989697
85597111	85597134	2	-	26780180	A375	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	1.04021312853126	[]	[]	5	hSpCas9	negative selection	3989698
85596596	85596619	2	-	26780180	A375	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	1.41217530903294	[]	[]	7	hSpCas9	negative selection	3989699
85596585	85596608	2	+	26780180	A375	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	1.57497535900397	[]	[]	8	hSpCas9	negative selection	3989700
85597453	85597476	2	+	26780180	HT29	viability (GeCKOv2 library)	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	1.27890005226698	[]	[]	6	hSpCas9	negative selection	4097661
85596826	85596849	2	+	26780180	HT29	viability (GeCKOv2 library)	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.429936808724658	[]	[]	1	hSpCas9	negative selection	4097662
85597138	85597161	2	-	26780180	HT29	viability (GeCKOv2 library)	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.30121828809981	[]	[]	0	hSpCas9	negative selection	4097663
85597111	85597134	2	-	26780180	HT29	viability (GeCKOv2 library)	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	1.31856280992577	[]	[]	6	hSpCas9	negative selection	4097664
85596596	85596619	2	-	26780180	HT29	viability (GeCKOv2 library)	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	1.10173402217032	[]	[]	5	hSpCas9	negative selection	4097665
85596585	85596608	2	+	26780180	HT29	viability (GeCKOv2 library)	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.951076460055267	[]	[]	4	hSpCas9	negative selection	4097666
85596918	85596941	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGCAGTACCTTGCTTAGCCAGG	RNF181	ENSG00000168894	0.038734578135737524	[3]	[0,3]	1	hSpCas9	positive selection	4166846
85596834	85596857	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCAAATTCCAAAAGACACACGG	RNF181	ENSG00000168894	-0.24162836239769134	[3]	[1,1]	-5	hSpCas9	positive selection	4166847
85596892	85596915	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAATGCAGCTGGAATGGAAAAGG	RNF181	ENSG00000168894	-0.5217507328157402	[2]	[1,0]	-8	hSpCas9	positive selection	4166848
85596585	85596608	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.28472595624524205	[4]	[1,2]	-6	hSpCas9	positive selection	4166849
85596512	85596535	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCCCAGGTCACTTTTCAATAGG	RNF181	ENSG00000168894	-0.31462089849425956	[3]	[1,1]	-6	hSpCas9	positive selection	4166851
85596918	85596941	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGCAGTACCTTGCTTAGCCAGG	RNF181	ENSG00000168894	0.15269749935227128	[3]	[0,2,3,0]	1	hSpCas9	positive selection	4230868
85596834	85596857	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCAAATTCCAAAAGACACACGG	RNF181	ENSG00000168894	0.8929185836660111	[3]	[0,0,1,3]	6	hSpCas9	positive selection	4230869
85596892	85596915	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAATGCAGCTGGAATGGAAAAGG	RNF181	ENSG00000168894	-0.18772050687308545	[2]	[0,3,0,0]	-3	hSpCas9	positive selection	4230870
85596585	85596608	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.16828034755595336	[4]	[2,1,0,0]	-2	hSpCas9	positive selection	4230871
85596512	85596535	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCCCAGGTCACTTTTCAATAGG	RNF181	ENSG00000168894	1.0142615807956945	[3]	[4,2,1,3]	7	hSpCas9	positive selection	4230873
85596826	85596849	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.35481327924338446	[3]	[3,3]	7	hSpCas9	positive selection	4295214
85596596	85596619	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.06579292016862845	[2]	[2,1]	-1	hSpCas9	positive selection	4295215
85597138	85597161	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.05614203880060083	[3]	[3,1]	1	hSpCas9	positive selection	4295216
85597111	85597134	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.0631765680231059	[2]	[1,1]	1	hSpCas9	positive selection	4359468
85596585	85596608	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.2814737620606337	[3]	[3,3]	5	hSpCas9	positive selection	4359469
85597453	85597476	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.20392243260093962	[2]	[2,1]	4	hSpCas9	positive selection	4359470
85595833	85595855	2	+	27760321	OCIAML3	viability	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	0.29483897786214963	[518,497]	[426,568]	3	hSpCas9	negative selection	4435180
85596517	85596539	2	+	27760321	OCIAML3	viability	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	0.6850570487312773	[71,61]	[60,113]	7	hSpCas9	negative selection	4435181
85596538	85596560	2	+	27760321	OCIAML3	viability	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-1.9720581626800486	[4,4]	[0,0]	-9	hSpCas9	negative selection	4435182
85596629	85596651	2	+	27760321	OCIAML3	viability	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	0.012175157000400283	[720,634]	[521,548]	0	hSpCas9	negative selection	4435183
85596832	85596854	2	-	27760321	OCIAML3	viability	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	-0.26657160225808973	[207,180]	[136,111]	-3	hSpCas9	negative selection	4435184
85595833	85595855	2	+	27760321	OCIAML2	viability	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	-0.05927097846573959	[518,497]	[353,449]	-1	hSpCas9	negative selection	4518643
85596517	85596539	2	+	27760321	OCIAML2	viability	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	0.8846711850177975	[71,61]	[88,113]	9	hSpCas9	negative selection	4518644
85596538	85596560	2	+	27760321	OCIAML2	viability	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-2.0208035279450973	[4,4]	[0,0]	-9	hSpCas9	negative selection	4518645
85596629	85596651	2	+	27760321	OCIAML2	viability	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	0.25363939683567494	[720,634]	[558,775]	3	hSpCas9	negative selection	4518646
85596832	85596854	2	-	27760321	OCIAML2	viability	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	-0.4047089680193323	[207,180]	[118,117]	-5	hSpCas9	negative selection	4518647
85595833	85595855	2	+	27760321	MV411	viability	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	-0.8699604720604847	[518,497]	[59,369]	-5	hSpCas9	negative selection	4602106
85596517	85596539	2	+	27760321	MV411	viability	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	2.197694020267346	[71,61]	[262,110]	9	hSpCas9	negative selection	4602107
85596538	85596560	2	+	27760321	MV411	viability	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-1.7269795937653667	[4,4]	[0,0]	-8	hSpCas9	negative selection	4602108
85596629	85596651	2	+	27760321	MV411	viability	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	0.5238279562123946	[720,634]	[687,572]	4	hSpCas9	negative selection	4602109
85596832	85596854	2	-	27760321	MV411	viability	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	-0.17706792818844863	[207,180]	[175,18]	-1	hSpCas9	negative selection	4602110
85595833	85595855	2	+	27760321	HL60	viability	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	-0.13214505510265107	[518,497]	[416,339]	-1	hSpCas9	negative selection	4685569
85596517	85596539	2	+	27760321	HL60	viability	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	0.15986948041757953	[71,61]	[59,61]	2	hSpCas9	negative selection	4685570
85596538	85596560	2	+	27760321	HL60	viability	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-2.0348497555595033	[4,4]	[0,0]	-9	hSpCas9	negative selection	4685571
85596629	85596651	2	+	27760321	HL60	viability	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	0.24292166127140835	[720,634]	[741,560]	3	hSpCas9	negative selection	4685572
85596832	85596854	2	-	27760321	HL60	viability	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	1.0727314815817148	[207,180]	[279,389]	9	hSpCas9	negative selection	4685573
85595833	85595855	2	+	27760321	HT1080	viability	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	0.028590467975237677	[497,388]	[205,151]	0	hSpCas9	negative selection	4769032
85596517	85596539	2	+	27760321	HT1080	viability	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	0.48987738081256804	[61,48]	[0,63]	2	hSpCas9	negative selection	4769033
85596538	85596560	2	+	27760321	HT1080	viability	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-0.8443172389209588	[4,3]	[0,0]	-4	hSpCas9	negative selection	4769034
85596629	85596651	2	+	27760321	HT1080	viability	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	-0.8211083792536512	[634,495]	[32,230]	-3	hSpCas9	negative selection	4769035
85596832	85596854	2	-	27760321	HT1080	viability	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	-6.002932860374814	[180,140]	[0,0]	-9	hSpCas9	negative selection	4769036
85595833	85595855	2	+	27760321	HT29	viability after 7 days	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	0.07656522081851574	[497,388]	[612,438,747]	1	hSpCas9	negative selection	4852495
85596517	85596539	2	+	27760321	HT29	viability after 7 days	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	0.2709333864604484	[61,48]	[122,129,12]	4	hSpCas9	negative selection	4852496
85596538	85596560	2	+	27760321	HT29	viability after 7 days	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-2.533977492470223	[4,3]	[0,0,0]	-9	hSpCas9	negative selection	4852497
85596629	85596651	2	+	27760321	HT29	viability after 7 days	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	0.02108040416447554	[634,495]	[869,743,620]	0	hSpCas9	negative selection	4852498
85596832	85596854	2	-	27760321	HT29	viability after 7 days	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	-0.7439639953712214	[180,140]	[158,104,111]	-8	hSpCas9	negative selection	4852499
85595833	85595855	2	+	27760321	HT29	viability after 25 days	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	-0.48848311848661985	[497,388]	[359,261,472]	-4	hSpCas9	negative selection	4935958
85596517	85596539	2	+	27760321	HT29	viability after 25 days	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	-0.5834422570114022	[61,48]	[35,0,95]	-5	hSpCas9	negative selection	4935959
85596538	85596560	2	+	27760321	HT29	viability after 25 days	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-2.3639995037674826	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	4935960
85596629	85596651	2	+	27760321	HT29	viability after 25 days	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	-0.6289008854877725	[634,495]	[329,361,583]	-5	hSpCas9	negative selection	4935961
85596832	85596854	2	-	27760321	HT29	viability after 25 days	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	-0.018905703536948648	[180,140]	[301,146,76]	0	hSpCas9	negative selection	4935962
85595833	85595855	2	+	27760321	HT29	viability after 22 days	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	-0.6751960120328617	[497,388]	[212,348,404]	-5	hSpCas9	negative selection	5019421
85596517	85596539	2	+	27760321	HT29	viability after 22 days	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	0.41503328703025133	[61,48]	[144,48,60]	4	hSpCas9	negative selection	5019422
85596538	85596560	2	+	27760321	HT29	viability after 22 days	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-2.381318135626742	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	5019423
85596629	85596651	2	+	27760321	HT29	viability after 22 days	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	-0.6296361977368622	[634,495]	[670,371,215]	-5	hSpCas9	negative selection	5019424
85596832	85596854	2	-	27760321	HT29	viability after 22 days	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	0.14544558066890279	[180,140]	[245,209,159]	1	hSpCas9	negative selection	5019425
85595833	85595855	2	+	27760321	HT29	viability after 19 days	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	-0.5415127665102967	[497,388]	[442,419,197]	-5	hSpCas9	negative selection	5102884
85596517	85596539	2	+	27760321	HT29	viability after 19 days	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	-1.1457633223543864	[61,48]	[29,20,34]	-7	hSpCas9	negative selection	5102885
85596538	85596560	2	+	27760321	HT29	viability after 19 days	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-2.365478083203529	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	5102886
85596629	85596651	2	+	27760321	HT29	viability after 19 days	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	-1.0747077096996756	[634,495]	[366,218,339]	-6	hSpCas9	negative selection	5102887
85596832	85596854	2	-	27760321	HT29	viability after 19 days	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	-0.36530024428526686	[180,140]	[119,262,46]	-3	hSpCas9	negative selection	5102888
85595833	85595855	2	+	27760321	HT29	viability after 16 days	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	-0.5735520230290341	[497,388]	[312,345,338]	-5	hSpCas9	negative selection	5186347
85596517	85596539	2	+	27760321	HT29	viability after 16 days	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	-0.4567468477070795	[61,48]	[51,62,20]	-4	hSpCas9	negative selection	5186348
85596538	85596560	2	+	27760321	HT29	viability after 16 days	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-2.334013630782607	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	5186349
85596629	85596651	2	+	27760321	HT29	viability after 16 days	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	-0.16360702488531959	[634,495]	[742,502,466]	-2	hSpCas9	negative selection	5186350
85596832	85596854	2	-	27760321	HT29	viability after 16 days	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	-0.3084233062124906	[180,140]	[201,169,68]	-3	hSpCas9	negative selection	5186351
85595833	85595855	2	+	27760321	HT29	viability after 13 days	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	-0.6608141194290338	[497,388]	[313,194,458]	-6	hSpCas9	negative selection	5269810
85596517	85596539	2	+	27760321	HT29	viability after 13 days	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	0.1497690752901355	[61,48]	[137,16,59]	1	hSpCas9	negative selection	5269811
85596538	85596560	2	+	27760321	HT29	viability after 13 days	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	0.324362639266476	[4,3]	[0,0,16]	4	hSpCas9	negative selection	5269812
85596629	85596651	2	+	27760321	HT29	viability after 13 days	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	-0.2837180986485769	[634,495]	[708,481,431]	-3	hSpCas9	negative selection	5269813
85596832	85596854	2	-	27760321	HT29	viability after 13 days	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	0.07101452198852742	[180,140]	[195,255,139]	0	hSpCas9	negative selection	5269814
85595833	85595855	2	+	27760321	HT29	viability after 10 days	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	-0.47156753652107386	[497,388]	[233,532,433]	-5	hSpCas9	negative selection	5353273
85596517	85596539	2	+	27760321	HT29	viability after 10 days	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	1.0576241113597125	[61,48]	[217,150,65]	9	hSpCas9	negative selection	5353274
85596538	85596560	2	+	27760321	HT29	viability after 10 days	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-1.7543125784870597	[4,3]	[2,0,0]	-9	hSpCas9	negative selection	5353275
85596629	85596651	2	+	27760321	HT29	viability after 10 days	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	-0.20521749140540746	[634,495]	[434,865,544]	-3	hSpCas9	negative selection	5353276
85596832	85596854	2	-	27760321	HT29	viability after 10 days	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	0.19709674177268932	[180,140]	[257,313,123]	2	hSpCas9	negative selection	5353277
85595833	85595855	2	+	27760321	MOLM13	viability	CTGCTGGAGCTCGCAAGGTGGG	RNF181	ENSG00000168894	-0.03208856525483403	[518,497]	[320,246]	0	hSpCas9	negative selection	5436736
85596517	85596539	2	+	27760321	MOLM13	viability	AGGTCACTTTTCAATAGGATGG	RNF181	ENSG00000168894	1.6311920018259678	[71,61]	[240,10]	9	hSpCas9	negative selection	5436737
85596538	85596560	2	+	27760321	MOLM13	viability	GACTTTGAAGACTTGGGGTTGG	RNF181	ENSG00000168894	-1.5009227809377714	[4,4]	[0,0]	-7	hSpCas9	negative selection	5436738
85596629	85596651	2	+	27760321	MOLM13	viability	TCATCAGAGGCTCTCAGGCTGG	RNF181	ENSG00000168894	0.16505313743396033	[720,634]	[480,382]	1	hSpCas9	negative selection	5436739
85596832	85596854	2	-	27760321	MOLM13	viability	AAATTCCAAAAGACACACGGGG	RNF181	ENSG00000168894	-1.6700007329482858	[207,180]	[28,38]	-7	hSpCas9	negative selection	5436740
85595736	85595759	2	+	27661255	K562	viability	GAGGGCTGTGTCAGAAGGCTGGG	RNF181	ENSG00000168894	0.22560904506151164	[592,718]	[676,553]	7	dCas9-KRAB	negative selection	5507909
85595958	85595981	2	+	27661255	K562	viability	GTAATCTGGAGTGTTAGTACGGG	RNF181	ENSG00000168894	-0.03411529909000721	[1501,1620]	[1317,1129]	-1	dCas9-KRAB	negative selection	5507910
85595974	85595997	2	+	27661255	K562	viability	GTACGGGCGGCGAGACTGAGGGG	RNF181	ENSG00000168894	0.3216973326526291	[1000,1120]	[1143,982]	9	dCas9-KRAB	negative selection	5507911
85596112	85596135	2	+	27661255	K562	viability	GCTCTGGGAGGTCTCAGAGAAGG	RNF181	ENSG00000168894	-0.05598171694256027	[281,327]	[250,218]	-2	dCas9-KRAB	negative selection	5507912
85595797	85595820	2	-	27661255	K562	viability	GTCTCCTGCTCAGGGTCCGACGG	RNF181	ENSG00000168894	-0.2088534879044334	[684,658]	[521,415]	-6	dCas9-KRAB	negative selection	5507913
85596826	85596849	2	+	27260156	BXPC3	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.2559686954944852	[663]	[813,836,735,935]	5	hSpCas9	negative selection	5567674
85596596	85596619	2	-	27260156	BXPC3	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.029705290861417155	[352]	[316,442,310,442]	0	hSpCas9	negative selection	5567675
85597138	85597161	2	-	27260156	BXPC3	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.10850392883564712	[500]	[522,519,489,750]	2	hSpCas9	negative selection	5567676
85597111	85597134	2	-	27260156	BXPC3	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	-0.060593898239920785	[204]	[159,165,212,300]	-1	hSpCas9	negative selection	5631928
85596585	85596608	2	+	27260156	BXPC3	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.15473623822084187	[591]	[498,579,553,596]	-4	hSpCas9	negative selection	5631929
85597453	85597476	2	+	27260156	BXPC3	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.022871281262080156	[260]	[245,289,288,285]	0	hSpCas9	negative selection	5631930
85596826	85596849	2	+	27260156	A673	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.15337449111905443	[663]	[888,810,881,969]	3	hSpCas9	negative selection	5688925
85596596	85596619	2	-	27260156	A673	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.1826658513148155	[352]	[587,421,380,550]	4	hSpCas9	negative selection	5688926
85597138	85597161	2	-	27260156	A673	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.11891994778460772	[500]	[679,557,573,814]	3	hSpCas9	negative selection	5688927
85597111	85597134	2	-	27260156	A673	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.12501248180779356	[204]	[247,216,272,337]	3	hSpCas9	negative selection	5753179
85596585	85596608	2	+	27260156	A673	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.1779564545634514	[591]	[631,492,744,645]	-4	hSpCas9	negative selection	5753180
85597453	85597476	2	+	27260156	A673	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.03814143631743516	[260]	[370,247,309,299]	-1	hSpCas9	negative selection	5753181
85596826	85596849	2	+	27260156	A375	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.4827642269885555	[663]	[1230,995,937,1146]	7	hSpCas9	negative selection	5810176
85596596	85596619	2	-	27260156	A375	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.1699553728633773	[352]	[472,384,290,323]	-2	hSpCas9	negative selection	5810177
85597138	85597161	2	-	27260156	A375	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.2268890736048168	[500]	[682,1242,644,290]	3	hSpCas9	negative selection	5810178
85597111	85597134	2	-	27260156	A375	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.03950294822245892	[204]	[216,458,175,169]	0	hSpCas9	negative selection	5874430
85596585	85596608	2	+	27260156	A375	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-1.0158192614527586	[591]	[392,286,362,318]	-8	hSpCas9	negative selection	5874431
85597453	85597476	2	+	27260156	A375	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.04318579117620425	[260]	[163,316,389,375]	0	hSpCas9	negative selection	5874432
85596826	85596849	2	+	27260156	COLO741	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.19414474056918385	[663]	[1070,918,930]	4	hSpCas9	negative selection	5931427
85596596	85596619	2	-	27260156	COLO741	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.17814112435605536	[352]	[507,530,491]	4	hSpCas9	negative selection	5931428
85597138	85597161	2	-	27260156	COLO741	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.20288365861980773	[500]	[909,728,594]	4	hSpCas9	negative selection	5931429
85597111	85597134	2	-	27260156	COLO741	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.038243377338864404	[204]	[334,252,226]	0	hSpCas9	negative selection	5995681
85596585	85596608	2	+	27260156	COLO741	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.14903036871900535	[591]	[665,825,560]	-3	hSpCas9	negative selection	5995682
85597453	85597476	2	+	27260156	COLO741	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.10003288644320718	[260]	[478,195,402]	2	hSpCas9	negative selection	5995683
85596826	85596849	2	+	27260156	CAL120	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.2563314530507764	[663]	[846,1030,1059]	4	hSpCas9	negative selection	6052678
85596596	85596619	2	-	27260156	CAL120	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.2816779941417733	[352]	[441,562,581]	4	hSpCas9	negative selection	6052679
85597138	85597161	2	-	27260156	CAL120	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.5364262668673272	[500]	[545,451,310]	-6	hSpCas9	negative selection	6052680
85597111	85597134	2	-	27260156	CAL120	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	-0.008037604842558776	[204]	[282,208,272]	0	hSpCas9	negative selection	6116932
85596585	85596608	2	+	27260156	CAL120	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.23821892917256718	[591]	[513,731,610]	-3	hSpCas9	negative selection	6116933
85597453	85597476	2	+	27260156	CAL120	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.28068852453384396	[260]	[218,484,451]	4	hSpCas9	negative selection	6116934
85596826	85596849	2	+	27260156	CADOES1	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.4316247941351765	[663]	[909,764,909,742]	7	hSpCas9	negative selection	6173929
85596596	85596619	2	-	27260156	CADOES1	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.23503055665698774	[352]	[294,323,214,281]	-4	hSpCas9	negative selection	6173930
85597138	85597161	2	-	27260156	CADOES1	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.013397795724234815	[500]	[421,380,543,500]	0	hSpCas9	negative selection	6173931
85597111	85597134	2	-	27260156	CADOES1	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.14678310472614542	[204]	[134,255,206,247]	2	hSpCas9	negative selection	6238183
85596585	85596608	2	+	27260156	CADOES1	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.13197718610202794	[591]	[531,574,449,450]	-2	hSpCas9	negative selection	6238184
85597453	85597476	2	+	27260156	CADOES1	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.11886270492150564	[260]	[224,259,268,136]	-2	hSpCas9	negative selection	6238185
85596826	85596849	2	+	27260156	EWS502	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.4259298137319275	[663]	[987,867,923,996]	7	hSpCas9	negative selection	6295180
85596596	85596619	2	-	27260156	EWS502	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.14869312913122118	[352]	[309,425,346,258]	-3	hSpCas9	negative selection	6295181
85597138	85597161	2	-	27260156	EWS502	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.09137443936679561	[500]	[432,569,482,509]	-2	hSpCas9	negative selection	6295182
85597111	85597134	2	-	27260156	EWS502	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.22398057896931267	[204]	[269,190,325,225]	4	hSpCas9	negative selection	6359434
85596585	85596608	2	+	27260156	EWS502	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.333923837573018	[591]	[440,404,605,551]	-5	hSpCas9	negative selection	6359435
85597453	85597476	2	+	27260156	EWS502	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.3154866031204526	[260]	[143,240,199,317]	-5	hSpCas9	negative selection	6359436
85596826	85596849	2	+	27260156	EW8	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.4921683418010897	[663]	[948,667,740,690]	8	hSpCas9	negative selection	6416431
85596596	85596619	2	-	27260156	EW8	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.21533536116738564	[352]	[511,262,339,230]	4	hSpCas9	negative selection	6416432
85597138	85597161	2	-	27260156	EW8	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.2938426039344136	[500]	[299,437,259,334]	-5	hSpCas9	negative selection	6416433
85597111	85597134	2	-	27260156	EW8	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.04928290234460908	[204]	[251,172,136,139]	0	hSpCas9	negative selection	6480685
85596585	85596608	2	+	27260156	EW8	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.2190552890198344	[591]	[393,369,352,537]	-4	hSpCas9	negative selection	6480686
85597453	85597476	2	+	27260156	EW8	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.2894354224247684	[260]	[258,289,171,326]	5	hSpCas9	negative selection	6480687
85596826	85596849	2	+	27260156	CORL105	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.25619239701944785	[663]	[773,928,1182,861]	5	hSpCas9	negative selection	6537682
85596596	85596619	2	-	27260156	CORL105	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.36535695556383924	[352]	[316,268,359,343]	-6	hSpCas9	negative selection	6537683
85597138	85597161	2	-	27260156	CORL105	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.22048022480453106	[500]	[572,298,551,602]	-4	hSpCas9	negative selection	6537684
85597111	85597134	2	-	27260156	CORL105	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.14419002868587394	[204]	[281,136,368,291]	2	hSpCas9	negative selection	6601936
85596585	85596608	2	+	27260156	CORL105	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.4697472669482926	[591]	[710,482,381,414]	-7	hSpCas9	negative selection	6601937
85597453	85597476	2	+	27260156	CORL105	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.11567272874674506	[260]	[298,352,308,357]	2	hSpCas9	negative selection	6601938
85596826	85596849	2	+	27260156	HS294T	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.3893221859283508	[663]	[273,373,347,355]	5	hSpCas9	negative selection	6658933
85596596	85596619	2	-	27260156	HS294T	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.0031918784212905393	[352]	[135,111,130,174]	0	hSpCas9	negative selection	6658934
85597138	85597161	2	-	27260156	HS294T	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.0029699044088779686	[500]	[108,147,337,189]	0	hSpCas9	negative selection	6658935
85597111	85597134	2	-	27260156	HS294T	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.17069008654563156	[204]	[63,93,90,113]	2	hSpCas9	negative selection	6723187
85596585	85596608	2	+	27260156	HS294T	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.6168314308075389	[591]	[110,136,176,180]	-7	hSpCas9	negative selection	6723188
85597453	85597476	2	+	27260156	HS294T	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.04329125658470223	[260]	[90,85,84,136]	0	hSpCas9	negative selection	6723189
85596826	85596849	2	+	27260156	HCC44	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.20525227600698837	[663]	[982,673,1062,809]	3	hSpCas9	negative selection	6780184
85596596	85596619	2	-	27260156	HCC44	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.2513330914980031	[352]	[691,251,505,502]	4	hSpCas9	negative selection	6780185
85597138	85597161	2	-	27260156	HCC44	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.4631747876309308	[500]	[423,267,553,439]	-6	hSpCas9	negative selection	6780186
85597111	85597134	2	-	27260156	HCC44	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.1744795068488254	[204]	[175,167,516,233]	2	hSpCas9	negative selection	6844438
85596585	85596608	2	+	27260156	HCC44	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.5363709439524282	[591]	[440,495,562,356]	-7	hSpCas9	negative selection	6844439
85597453	85597476	2	+	27260156	HCC44	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.2815939237714178	[260]	[256,187,212,312]	-4	hSpCas9	negative selection	6844440
85596826	85596849	2	+	27260156	G402	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.7973782626185152	[663]	[1398,1485,1672,1087]	8	hSpCas9	negative selection	6901435
85596596	85596619	2	-	27260156	G402	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.721877658557246	[352]	[181,405,305,151]	-7	hSpCas9	negative selection	6901436
85597138	85597161	2	-	27260156	G402	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.15669745669775814	[500]	[619,493,691,399]	-2	hSpCas9	negative selection	6901437
85597111	85597134	2	-	27260156	G402	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.1740306134494558	[204]	[125,317,332,327]	2	hSpCas9	negative selection	6965689
85596585	85596608	2	+	27260156	G402	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.7577674457575417	[591]	[454,602,396,273]	-7	hSpCas9	negative selection	6965690
85597453	85597476	2	+	27260156	G402	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.5070683190310574	[260]	[260,1121,219,227]	6	hSpCas9	negative selection	6965691
85596826	85596849	2	+	27260156	L33	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.14665346692232373	[663]	[656,334,460,733]	3	hSpCas9	negative selection	7022686
85596596	85596619	2	-	27260156	L33	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.14449718660669492	[352]	[286,209,209,428]	3	hSpCas9	negative selection	7022687
85597138	85597161	2	-	27260156	L33	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.25143235361259436	[500]	[454,299,339,659]	5	hSpCas9	negative selection	7022688
85597111	85597134	2	-	27260156	L33	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	-0.08061434977116222	[204]	[205,136,86,96]	-2	hSpCas9	negative selection	7086940
85596585	85596608	2	+	27260156	L33	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.6716246765296356	[591]	[408,147,232,344]	-9	hSpCas9	negative selection	7086941
85597453	85597476	2	+	27260156	L33	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.2322871693588504	[260]	[286,137,266,179]	5	hSpCas9	negative selection	7086942
85596826	85596849	2	+	27260156	K562	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.68380788062641	[663]	[1080,898,1149,690]	8	hSpCas9	negative selection	7143937
85596596	85596619	2	-	27260156	K562	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.09995395375636634	[352]	[321,372,143,330]	-1	hSpCas9	negative selection	7143938
85597138	85597161	2	-	27260156	K562	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.29628267935696123	[500]	[612,333,224,300]	-4	hSpCas9	negative selection	7143939
85597111	85597134	2	-	27260156	K562	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.5973624547294891	[204]	[182,185,324,380]	7	hSpCas9	negative selection	7208191
85596585	85596608	2	+	27260156	K562	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-1.0072366791544733	[591]	[345,269,176,258]	-8	hSpCas9	negative selection	7208192
85597453	85597476	2	+	27260156	K562	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.802842016550789	[260]	[155,236,116,38]	-7	hSpCas9	negative selection	7208193
85596826	85596849	2	+	27260156	HT29	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.29140141074228787	[663]	[1357,905,995,736]	6	hSpCas9	negative selection	7265188
85596596	85596619	2	-	27260156	HT29	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.05620521823270547	[352]	[532,485,375,401]	1	hSpCas9	negative selection	7265189
85597138	85597161	2	-	27260156	HT29	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.10169126743807409	[500]	[598,917,674,459]	2	hSpCas9	negative selection	7265190
85597111	85597134	2	-	27260156	HT29	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	-0.13611741266493627	[204]	[310,246,248,119]	-3	hSpCas9	negative selection	7329442
85596585	85596608	2	+	27260156	HT29	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.3225808391448762	[591]	[648,786,413,482]	-6	hSpCas9	negative selection	7329443
85597453	85597476	2	+	27260156	HT29	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.1997494327408431	[260]	[277,218,340,261]	-4	hSpCas9	negative selection	7329444
85596826	85596849	2	+	27260156	MHHES1	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.46309920872330324	[663]	[1143,1057,1185,786]	7	hSpCas9	negative selection	7386439
85596596	85596619	2	-	27260156	MHHES1	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.10093381410175145	[352]	[392,352,585,187]	-2	hSpCas9	negative selection	7386440
85597138	85597161	2	-	27260156	MHHES1	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.05469858481426044	[500]	[562,590,433,571]	-1	hSpCas9	negative selection	7386441
85597111	85597134	2	-	27260156	MHHES1	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.0661065990930485	[204]	[280,344,175,186]	1	hSpCas9	negative selection	7450693
85596585	85596608	2	+	27260156	MHHES1	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.5360395040162248	[591]	[639,339,656,251]	-7	hSpCas9	negative selection	7450694
85597453	85597476	2	+	27260156	MHHES1	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.7291474592975125	[260]	[169,247,160,140]	-8	hSpCas9	negative selection	7450695
85596826	85596849	2	+	27260156	MEWO	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.26073391309684335	[663]	[889,717,652]	5	hSpCas9	negative selection	7507690
85596596	85596619	2	-	27260156	MEWO	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.10833326533634707	[352]	[411,312,353]	2	hSpCas9	negative selection	7507691
85597138	85597161	2	-	27260156	MEWO	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.15129019218405748	[500]	[578,484,508]	3	hSpCas9	negative selection	7507692
85597111	85597134	2	-	27260156	MEWO	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.03429957887255819	[204]	[252,223,122]	0	hSpCas9	negative selection	7571944
85596585	85596608	2	+	27260156	MEWO	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.11224991778061924	[591]	[537,517,485]	-2	hSpCas9	negative selection	7571945
85597453	85597476	2	+	27260156	MEWO	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.17326217888516326	[260]	[227,231,356]	4	hSpCas9	negative selection	7571946
85596826	85596849	2	+	27260156	LNCAPCLONEFGC	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.5438403058253881	[663]	[1032,833,770,852]	8	hSpCas9	negative selection	7628941
85596596	85596619	2	-	27260156	LNCAPCLONEFGC	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.13868092265386517	[352]	[322,267,506,338]	2	hSpCas9	negative selection	7628942
85597138	85597161	2	-	27260156	LNCAPCLONEFGC	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.1415714355424303	[500]	[478,430,559,545]	2	hSpCas9	negative selection	7628943
85597111	85597134	2	-	27260156	LNCAPCLONEFGC	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.061990488806581645	[204]	[134,213,172,249]	0	hSpCas9	negative selection	7693195
85596585	85596608	2	+	27260156	LNCAPCLONEFGC	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.22756997847637367	[591]	[435,421,541,446]	-4	hSpCas9	negative selection	7693196
85597453	85597476	2	+	27260156	LNCAPCLONEFGC	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.2053756580965963	[260]	[162,232,346,362]	3	hSpCas9	negative selection	7693197
85596826	85596849	2	+	27260156	PANC0327	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.39246012610180947	[663]	[1027,777,691,618]	6	hSpCas9	negative selection	7750192
85596596	85596619	2	-	27260156	PANC0327	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.06162250404227193	[352]	[368,348,221,260]	-1	hSpCas9	negative selection	7750193
85597138	85597161	2	-	27260156	PANC0327	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.11120368163673294	[500]	[516,330,388,429]	-2	hSpCas9	negative selection	7750194
85597111	85597134	2	-	27260156	PANC0327	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.044843510904277295	[204]	[192,77,239,254]	0	hSpCas9	negative selection	7814446
85596585	85596608	2	+	27260156	PANC0327	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.10411298691469689	[591]	[611,319,948,415]	1	hSpCas9	negative selection	7814447
85597453	85597476	2	+	27260156	PANC0327	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.06936444498924732	[260]	[229,266,303,167]	1	hSpCas9	negative selection	7814448
85596826	85596849	2	+	27260156	NCIH2009	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.5357363225087449	[663]	[1846,1158,1128]	7	hSpCas9	negative selection	7871443
85596596	85596619	2	-	27260156	NCIH2009	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.2171141726602504	[352]	[472,466,340]	-3	hSpCas9	negative selection	7871444
85597138	85597161	2	-	27260156	NCIH2009	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.4435412385808965	[500]	[623,451,489]	-5	hSpCas9	negative selection	7871445
85597111	85597134	2	-	27260156	NCIH2009	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	-0.10427608930782628	[204]	[259,244,292]	-1	hSpCas9	negative selection	7935697
85596585	85596608	2	+	27260156	NCIH2009	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.5007648354360943	[591]	[846,668,286]	-6	hSpCas9	negative selection	7935698
85597453	85597476	2	+	27260156	NCIH2009	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.3349322721035861	[260]	[348,215,314]	-4	hSpCas9	negative selection	7935699
85596826	85596849	2	+	27260156	NCIH1373	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.8254899835651065	[663]	[2075,1142,1071,290]	8	hSpCas9	negative selection	7992694
85596596	85596619	2	-	27260156	NCIH1373	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-1.1262199142957607	[352]	[116,196,172,59]	-8	hSpCas9	negative selection	7992695
85597138	85597161	2	-	27260156	NCIH1373	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.29740460533833835	[500]	[588,260,421,158]	-3	hSpCas9	negative selection	7992696
85597111	85597134	2	-	27260156	NCIH1373	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.9620038476315094	[204]	[651,251,378,148]	8	hSpCas9	negative selection	8056948
85596585	85596608	2	+	27260156	NCIH1373	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.9715843784250638	[591]	[246,519,287,67]	-7	hSpCas9	negative selection	8056949
85597453	85597476	2	+	27260156	NCIH1373	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.17201261205080964	[260]	[397,416,216,74]	1	hSpCas9	negative selection	8056950
85596826	85596849	2	+	27260156	PATU8902	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	1.141275797258022	[663]	[2049,3141,1255,1882]	9	hSpCas9	negative selection	8113945
85596596	85596619	2	-	27260156	PATU8902	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.7005454520906347	[352]	[524,346,206,129]	-6	hSpCas9	negative selection	8113946
85597138	85597161	2	-	27260156	PATU8902	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.38872062975718874	[500]	[897,362,296,637]	-4	hSpCas9	negative selection	8113947
85597111	85597134	2	-	27260156	PATU8902	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.2238366294571119	[204]	[392,281,243,447]	2	hSpCas9	negative selection	8178199
85596585	85596608	2	+	27260156	PATU8902	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.685737858950004	[591]	[426,315,311,1115]	-6	hSpCas9	negative selection	8178200
85597453	85597476	2	+	27260156	PATU8902	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.5614649285926476	[260]	[304,685,322,933]	6	hSpCas9	negative selection	8178201
85596826	85596849	2	+	27260156	PANC1	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.05912832484112496	[663]	[581,422,806,531]	0	hSpCas9	negative selection	8235196
85596596	85596619	2	-	27260156	PANC1	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.1930943732849231	[352]	[295,514,339,276]	3	hSpCas9	negative selection	8235197
85597138	85597161	2	-	27260156	PANC1	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.07108992512115779	[500]	[533,465,356,444]	1	hSpCas9	negative selection	8235198
85597111	85597134	2	-	27260156	PANC1	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.26333481893826394	[204]	[244,174,231,185]	4	hSpCas9	negative selection	8299450
85596585	85596608	2	+	27260156	PANC1	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.25027847006153503	[591]	[457,581,512,216]	-4	hSpCas9	negative selection	8299451
85597453	85597476	2	+	27260156	PANC1	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.16243546867428238	[260]	[183,341,265,230]	2	hSpCas9	negative selection	8299452
85596826	85596849	2	+	27260156	PANC0813	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.6438526110952224	[663]	[1394,1176,1209,1112]	8	hSpCas9	negative selection	8356447
85596596	85596619	2	-	27260156	PANC0813	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.19852171454099682	[352]	[526,363,358,646]	3	hSpCas9	negative selection	8356448
85597138	85597161	2	-	27260156	PANC0813	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.10896027972977411	[500]	[628,753,476,673]	1	hSpCas9	negative selection	8356449
85597111	85597134	2	-	27260156	PANC0813	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	-0.009959377193998753	[204]	[333,201,176,250]	0	hSpCas9	negative selection	8420701
85596585	85596608	2	+	27260156	PANC0813	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.12180434927155914	[591]	[984,502,433,662]	-2	hSpCas9	negative selection	8420702
85597453	85597476	2	+	27260156	PANC0813	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.08896978959496504	[260]	[409,426,256,222]	1	hSpCas9	negative selection	8420703
85596826	85596849	2	+	27260156	RDES	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.5124112065821301	[663]	[890,909,1228,1408]	7	hSpCas9	negative selection	8477698
85596596	85596619	2	-	27260156	RDES	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.2887351720513958	[352]	[342,343,317,303]	-5	hSpCas9	negative selection	8477699
85597138	85597161	2	-	27260156	RDES	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.1328652932342345	[500]	[548,507,616,387]	-2	hSpCas9	negative selection	8477700
85597111	85597134	2	-	27260156	RDES	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.0531117800658889	[204]	[189,179,252,388]	0	hSpCas9	negative selection	8541952
85596585	85596608	2	+	27260156	RDES	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.3467941341828709	[591]	[428,502,551,691]	-5	hSpCas9	negative selection	8541953
85597453	85597476	2	+	27260156	RDES	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.215198515549065	[260]	[209,203,379,251]	-4	hSpCas9	negative selection	8541954
85596826	85596849	2	+	27260156	PC3	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.17289765532628354	[663]	[464,783,1273,713]	4	hSpCas9	negative selection	8598949
85596596	85596619	2	-	27260156	PC3	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.02272555028519052	[352]	[154,361,600,427]	0	hSpCas9	negative selection	8598950
85597138	85597161	2	-	27260156	PC3	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.13317363369727936	[500]	[327,465,972,643]	3	hSpCas9	negative selection	8598951
85597111	85597134	2	-	27260156	PC3	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	-0.21213250079717438	[204]	[136,110,319,194]	-5	hSpCas9	negative selection	8663203
85596585	85596608	2	+	27260156	PC3	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.9860388232171433	[591]	[156,133,737,385]	-9	hSpCas9	negative selection	8663204
85597453	85597476	2	+	27260156	PC3	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.2488373427306524	[260]	[301,203,555,231]	5	hSpCas9	negative selection	8663205
85596826	85596849	2	+	27260156	PATU8988T	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.14558432825012546	[663]	[524,787,827,702]	2	hSpCas9	negative selection	8720200
85596596	85596619	2	-	27260156	PATU8988T	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.07657907546447107	[352]	[205,310,480,440]	1	hSpCas9	negative selection	8720201
85597138	85597161	2	-	27260156	PATU8988T	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.5734755066497882	[500]	[767,619,699,789]	8	hSpCas9	negative selection	8720202
85597111	85597134	2	-	27260156	PATU8988T	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.20466656056234778	[204]	[220,212,242,234]	3	hSpCas9	negative selection	8784454
85596585	85596608	2	+	27260156	PATU8988T	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.22360150100130785	[591]	[381,521,376,699]	-4	hSpCas9	negative selection	8784455
85597453	85597476	2	+	27260156	PATU8988T	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.139743618644662	[260]	[344,391,132,251]	2	hSpCas9	negative selection	8784456
85596826	85596849	2	+	27260156	T47D	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.20290590330104796	[663]	[773,678,1082,1044]	4	hSpCas9	negative selection	8841451
85596596	85596619	2	-	27260156	T47D	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.029253235308402625	[352]	[479,415,403,377]	0	hSpCas9	negative selection	8841452
85597138	85597161	2	-	27260156	T47D	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.11281431577066696	[500]	[704,543,689,590]	2	hSpCas9	negative selection	8841453
85597111	85597134	2	-	27260156	T47D	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.3963471409104753	[204]	[313,254,263,433]	8	hSpCas9	negative selection	8905705
85596585	85596608	2	+	27260156	T47D	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.1629045225496454	[591]	[773,550,562,581]	-4	hSpCas9	negative selection	8905706
85597453	85597476	2	+	27260156	T47D	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.07050150751531825	[260]	[399,240,346,294]	1	hSpCas9	negative selection	8905707
85596826	85596849	2	+	27260156	SU8686	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.5284342999176729	[663]	[871,820,987,1172]	8	hSpCas9	negative selection	8962702
85596596	85596619	2	-	27260156	SU8686	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.22561881564103342	[352]	[252,327,235,392]	-4	hSpCas9	negative selection	8962703
85597138	85597161	2	-	27260156	SU8686	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.15280832331164	[500]	[378,446,455,521]	-3	hSpCas9	negative selection	8962704
85597111	85597134	2	-	27260156	SU8686	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.14322044101306153	[204]	[160,191,268,298]	2	hSpCas9	negative selection	9026956
85596585	85596608	2	+	27260156	SU8686	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.20632721970279783	[591]	[405,450,492,736]	-4	hSpCas9	negative selection	9026957
85597453	85597476	2	+	27260156	SU8686	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.01609711972636274	[260]	[225,279,278,233]	0	hSpCas9	negative selection	9026958
85596826	85596849	2	+	27260156	SKES1	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.2845000195714521	[663]	[952,874,744,688]	6	hSpCas9	negative selection	9083953
85596596	85596619	2	-	27260156	SKES1	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.23003055212458598	[352]	[253,635,555,226]	5	hSpCas9	negative selection	9083954
85597138	85597161	2	-	27260156	SKES1	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.14627959804278062	[500]	[550,726,551,413]	3	hSpCas9	negative selection	9083955
85597111	85597134	2	-	27260156	SKES1	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.12292094976353196	[204]	[310,199,230,162]	2	hSpCas9	negative selection	9148207
85596585	85596608	2	+	27260156	SKES1	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.15860633532274	[591]	[613,579,467,473]	-3	hSpCas9	negative selection	9148208
85597453	85597476	2	+	27260156	SKES1	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.25092722973202974	[260]	[209,307,163,202]	-5	hSpCas9	negative selection	9148209
85596826	85596849	2	+	27260156	TOV112D	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.3497687112462968	[663]	[716,1018,808,873]	6	hSpCas9	negative selection	9205204
85596596	85596619	2	-	27260156	TOV112D	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.26672245171123066	[352]	[693,461,320,259]	5	hSpCas9	negative selection	9205205
85597138	85597161	2	-	27260156	TOV112D	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	-0.12707928571269148	[500]	[555,503,401,395]	-2	hSpCas9	negative selection	9205206
85597111	85597134	2	-	27260156	TOV112D	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.2119924885365725	[204]	[167,306,175,308]	4	hSpCas9	negative selection	9269458
85596585	85596608	2	+	27260156	TOV112D	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.14698889292220396	[591]	[680,609,321,557]	-3	hSpCas9	negative selection	9269459
85597453	85597476	2	+	27260156	TOV112D	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.6483123421142436	[260]	[575,489,307,300]	9	hSpCas9	negative selection	9269460
85596826	85596849	2	+	27260156	TC71	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.1218256659173027	[663]	[765,739,653,952]	3	hSpCas9	negative selection	9326455
85596596	85596619	2	-	27260156	TC71	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	0.10856744452208084	[352]	[308,476,498,341]	2	hSpCas9	negative selection	9326456
85597138	85597161	2	-	27260156	TC71	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.046539218315804556	[500]	[519,592,535,571]	1	hSpCas9	negative selection	9326457
85597111	85597134	2	-	27260156	TC71	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.1362611503997111	[204]	[241,275,208,239]	3	hSpCas9	negative selection	9390709
85596585	85596608	2	+	27260156	TC71	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.2631754262757181	[591]	[497,508,469,647]	-6	hSpCas9	negative selection	9390710
85597453	85597476	2	+	27260156	TC71	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	-0.23849051149171108	[260]	[184,237,218,312]	-6	hSpCas9	negative selection	9390711
85596826	85596849	2	+	27260156	TC32	viability	CAAGTGCCCCGTGTGTCTTTTGG	RNF181	ENSG00000168894	0.5492244424917184	[663]	[849,631,1403,912]	8	hSpCas9	negative selection	9447706
85596596	85596619	2	-	27260156	TC32	viability	GAGGTTCTCAACCACAGTCTTGG	RNF181	ENSG00000168894	-0.034279087765786254	[352]	[310,272,473,260]	0	hSpCas9	negative selection	9447707
85597138	85597161	2	-	27260156	TC32	viability	CTCATAAGTGTCGTCATCAGTGG	RNF181	ENSG00000168894	0.22256226732164547	[500]	[580,414,547,672]	4	hSpCas9	negative selection	9447708
85597111	85597134	2	-	27260156	TC32	viability	CTCATAGCGGCACAAGGGACAGG	RNF181	ENSG00000168894	0.23949067568756277	[204]	[198,204,319,197]	4	hSpCas9	negative selection	9511960
85596585	85596608	2	+	27260156	TC32	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.38271177152373503	[591]	[429,366,443,465]	-6	hSpCas9	negative selection	9511961
85597453	85597476	2	+	27260156	TC32	viability	ACAGCAGCAGCAACACCGACTGG	RNF181	ENSG00000168894	0.2801111972197575	[260]	[249,251,421,293]	5	hSpCas9	negative selection	9511962
85596917	85596940	2	-	27869803	HPAFII	viability after 27 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.518554341648136	[242]	[140,45,NaN]	-4	hSpCas9	negative selection	9575989
85596917	85596940	2	-	27869803	HPAFII	viability after 15 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.34568439683112184	[242]	[358,314,NaN]	4	hSpCas9	negative selection	9658438
85596917	85596940	2	-	27869803	ASPC1	viability after 36 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-1.666874362120565	[622]	[56,129,26]	-9	hSpCas9	negative selection	9740887
85596917	85596940	2	-	27869803	PATU8988S	viability after 35 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.6056460122624461	[732]	[197,189,NaN]	-6	hSpCas9	negative selection	9823336
85596917	85596940	2	-	27869803	PATU8988S	viability after 31 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.40564037650973434	[732]	[228,209,NaN]	-4	hSpCas9	negative selection	9905785
85596917	85596940	2	-	27869803	HPAFII	viability after 35 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.19074335057939656	[242]	[143,66,NaN]	-1	hSpCas9	negative selection	9988234
85596917	85596940	2	-	27869803	HPAFII	viability after 31 days	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.19645035833548763	[242]	[163,69,NaN]	-1	hSpCas9	negative selection	10070683
85595817	85595840	2	+	28162770	P31FUJ	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	0.22024862080119667	[102]	[140]	2	hSpCas9	negative selection	10226338
85596585	85596608	2	+	28162770	P31FUJ	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.3268456943295167	[411]	[385]	-3	hSpCas9	negative selection	10226339
85596838	85596861	2	+	28162770	P31FUJ	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	-0.20228025963748286	[607]	[620]	-2	hSpCas9	negative selection	10226340
85596881	85596904	2	-	28162770	P31FUJ	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	-0.06287720297206634	[79]	[89]	0	hSpCas9	negative selection	10226341
85596602	85596625	2	+	28162770	P31FUJ	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	-0.05771549785628738	[402]	[454]	0	hSpCas9	negative selection	10226342
85596870	85596893	2	-	28162770	P31FUJ	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	0.16345808783383708	[347]	[457]	1	hSpCas9	negative selection	10226343
85596917	85596940	2	-	28162770	P31FUJ	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.2037840193834639	[514]	[696]	2	hSpCas9	negative selection	10226344
85595781	85595804	2	+	28162770	P31FUJ	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	0.15546838530167972	[135]	[177]	1	hSpCas9	negative selection	10226345
85595793	85595816	2	+	28162770	P31FUJ	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	0.13456886123415068	[299]	[386]	1	hSpCas9	negative selection	10226346
85595825	85595848	2	-	28162770	P31FUJ	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	-0.18779246949681302	[283]	[292]	-2	hSpCas9	negative selection	10226347
85595817	85595840	2	+	28162770	TF1	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	NaN	[NaN]	[133]	1	hSpCas9	negative selection	10395704
85596585	85596608	2	+	28162770	TF1	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	NaN	[NaN]	[593]	1	hSpCas9	negative selection	10395705
85596838	85596861	2	+	28162770	TF1	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	NaN	[NaN]	[433]	1	hSpCas9	negative selection	10395706
85596881	85596904	2	-	28162770	TF1	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	NaN	[NaN]	[179]	1	hSpCas9	negative selection	10395707
85596602	85596625	2	+	28162770	TF1	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	NaN	[NaN]	[359]	1	hSpCas9	negative selection	10395708
85596870	85596893	2	-	28162770	TF1	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	NaN	[NaN]	[480]	1	hSpCas9	negative selection	10395709
85596917	85596940	2	-	28162770	TF1	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	NaN	[NaN]	[595]	1	hSpCas9	negative selection	10395710
85595781	85595804	2	+	28162770	TF1	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10395711
85595793	85595816	2	+	28162770	TF1	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	NaN	[NaN]	[254]	1	hSpCas9	negative selection	10395712
85595825	85595848	2	-	28162770	TF1	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	NaN	[NaN]	[190]	1	hSpCas9	negative selection	10395713
85595817	85595840	2	+	28162770	SKM1	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	0.2869326735311586	[50]	[109]	3	hSpCas9	negative selection	10565070
85596585	85596608	2	+	28162770	SKM1	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.026821489910503593	[101]	[176]	0	hSpCas9	negative selection	10565071
85596838	85596861	2	+	28162770	SKM1	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	-0.2829285958129084	[180]	[262]	-2	hSpCas9	negative selection	10565072
85596881	85596904	2	-	28162770	SKM1	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	0.8218544917527193	[23]	[74]	7	hSpCas9	negative selection	10565073
85596602	85596625	2	+	28162770	SKM1	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	0.10399772053421752	[99]	[189]	1	hSpCas9	negative selection	10565074
85596870	85596893	2	-	28162770	SKM1	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	-0.4500329206350475	[118]	[153]	-4	hSpCas9	negative selection	10565075
85596917	85596940	2	-	28162770	SKM1	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.236891991031563	[119]	[249]	2	hSpCas9	negative selection	10565076
85595781	85595804	2	+	28162770	SKM1	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	-0.21056698593965828	[35]	[54]	-2	hSpCas9	negative selection	10565077
85595793	85595816	2	+	28162770	SKM1	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	0.23244608600037087	[90]	[188]	2	hSpCas9	negative selection	10565078
85595825	85595848	2	-	28162770	SKM1	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	0.02862067793976801	[60]	[109]	0	hSpCas9	negative selection	10565079
85595817	85595840	2	+	28162770	SKM1	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	0.2869326735311586	[50]	[109]	3	hSpCas9	negative selection	10734436
85596585	85596608	2	+	28162770	SKM1	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.026821489910503593	[101]	[176]	0	hSpCas9	negative selection	10734437
85596838	85596861	2	+	28162770	SKM1	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	-0.2829285958129084	[180]	[262]	-2	hSpCas9	negative selection	10734438
85596881	85596904	2	-	28162770	SKM1	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	0.8218544917527193	[23]	[74]	7	hSpCas9	negative selection	10734439
85596602	85596625	2	+	28162770	SKM1	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	0.10399772053421752	[99]	[189]	1	hSpCas9	negative selection	10734440
85596870	85596893	2	-	28162770	SKM1	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	-0.4500329206350475	[118]	[153]	-4	hSpCas9	negative selection	10734441
85596917	85596940	2	-	28162770	SKM1	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.236891991031563	[119]	[249]	2	hSpCas9	negative selection	10734442
85595781	85595804	2	+	28162770	SKM1	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	-0.21056698593965828	[35]	[54]	-2	hSpCas9	negative selection	10734443
85595793	85595816	2	+	28162770	SKM1	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	0.23244608600037087	[90]	[188]	2	hSpCas9	negative selection	10734444
85595825	85595848	2	-	28162770	SKM1	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	0.02862067793976801	[60]	[109]	0	hSpCas9	negative selection	10734445
85595817	85595840	2	+	28162770	PL21	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	0.24257488080971662	[133]	[68]	2	hSpCas9	negative selection	10903802
85596585	85596608	2	+	28162770	PL21	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-1.545977678046416	[368]	[54]	-7	hSpCas9	negative selection	10903803
85596838	85596861	2	+	28162770	PL21	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	-0.22372664416426136	[600]	[223]	-2	hSpCas9	negative selection	10903804
85596881	85596904	2	-	28162770	PL21	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	0.882949438608621	[75]	[60]	7	hSpCas9	negative selection	10903805
85596602	85596625	2	+	28162770	PL21	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	-0.030290125912546095	[419]	[178]	0	hSpCas9	negative selection	10903806
85596870	85596893	2	-	28162770	PL21	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	-0.0488879333505946	[327]	[137]	0	hSpCas9	negative selection	10903807
85596917	85596940	2	-	28162770	PL21	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.5090487629068208	[422]	[261]	4	hSpCas9	negative selection	10903808
85595781	85595804	2	+	28162770	PL21	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	0.4421124047952843	[114]	[67]	4	hSpCas9	negative selection	10903809
85595793	85595816	2	+	28162770	PL21	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	-1.0025753220706617	[266]	[57]	-6	hSpCas9	negative selection	10903810
85595825	85595848	2	-	28162770	PL21	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	0.8862043103554884	[224]	[180]	7	hSpCas9	negative selection	10903811
85595817	85595840	2	+	28162770	P31FUJ	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	0.22024862080119667	[102]	[140]	2	hSpCas9	negative selection	11073168
85596585	85596608	2	+	28162770	P31FUJ	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.3268456943295167	[411]	[385]	-3	hSpCas9	negative selection	11073169
85596838	85596861	2	+	28162770	P31FUJ	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	-0.20228025963748286	[607]	[620]	-2	hSpCas9	negative selection	11073170
85596881	85596904	2	-	28162770	P31FUJ	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	-0.06287720297206634	[79]	[89]	0	hSpCas9	negative selection	11073171
85596602	85596625	2	+	28162770	P31FUJ	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	-0.05771549785628738	[402]	[454]	0	hSpCas9	negative selection	11073172
85596870	85596893	2	-	28162770	P31FUJ	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	0.16345808783383708	[347]	[457]	1	hSpCas9	negative selection	11073173
85596917	85596940	2	-	28162770	P31FUJ	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.2037840193834639	[514]	[696]	2	hSpCas9	negative selection	11073174
85595781	85595804	2	+	28162770	P31FUJ	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	0.15546838530167972	[135]	[177]	1	hSpCas9	negative selection	11073175
85595793	85595816	2	+	28162770	P31FUJ	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	0.13456886123415068	[299]	[386]	1	hSpCas9	negative selection	11073176
85595825	85595848	2	-	28162770	P31FUJ	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	-0.18779246949681302	[283]	[292]	-2	hSpCas9	negative selection	11073177
85595817	85595840	2	+	28162770	OCIAML5	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	0.6583066134364757	[85]	[244]	6	hSpCas9	negative selection	11242534
85596585	85596608	2	+	28162770	OCIAML5	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.5063296910926569	[249]	[640]	4	hSpCas9	negative selection	11242535
85596838	85596861	2	+	28162770	OCIAML5	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	0.08715379906758103	[302]	[580]	0	hSpCas9	negative selection	11242536
85596881	85596904	2	-	28162770	OCIAML5	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	-0.6030390230240823	[68]	[81]	-4	hSpCas9	negative selection	11242537
85596602	85596625	2	+	28162770	OCIAML5	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	0.47163061687642094	[162]	[407]	4	hSpCas9	negative selection	11242538
85596870	85596893	2	-	28162770	OCIAML5	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	0.5446560310347643	[217]	[573]	5	hSpCas9	negative selection	11242539
85596917	85596940	2	-	28162770	OCIAML5	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.10641001643374648	[330]	[554]	-1	hSpCas9	negative selection	11242540
85595781	85595804	2	+	28162770	OCIAML5	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	-0.5998795472671956	[88]	[105]	-4	hSpCas9	negative selection	11242541
85595793	85595816	2	+	28162770	OCIAML5	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	0.533991861443081	[175]	[459]	4	hSpCas9	negative selection	11242542
85595825	85595848	2	-	28162770	OCIAML5	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	0.2589647415247468	[174]	[377]	2	hSpCas9	negative selection	11242543
85595817	85595840	2	+	28162770	EOL1	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	-0.032383506537579515	[263]	[135]	0	hSpCas9	negative selection	11411900
85596585	85596608	2	+	28162770	EOL1	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.47647435888266243	[426]	[312]	4	hSpCas9	negative selection	11411901
85596838	85596861	2	+	28162770	EOL1	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	-0.36249953108748323	[1041]	[426]	-3	hSpCas9	negative selection	11411902
85596881	85596904	2	-	28162770	EOL1	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	0.2640342378422015	[146]	[92]	2	hSpCas9	negative selection	11411903
85596602	85596625	2	+	28162770	EOL1	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	-0.4199581712920375	[804]	[316]	-3	hSpCas9	negative selection	11411904
85596870	85596893	2	-	28162770	EOL1	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	-0.34831950486594154	[794]	[328]	-3	hSpCas9	negative selection	11411905
85596917	85596940	2	-	28162770	EOL1	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.7826300831096015	[490]	[444]	7	hSpCas9	negative selection	11411906
85595781	85595804	2	+	28162770	EOL1	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	-0.4518281073392043	[134]	[51]	-3	hSpCas9	negative selection	11411907
85595793	85595816	2	+	28162770	EOL1	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	0.2744202241829219	[316]	[201]	2	hSpCas9	negative selection	11411908
85595825	85595848	2	-	28162770	EOL1	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	0.4722878083354921	[300]	[219]	4	hSpCas9	negative selection	11411909
85595817	85595840	2	+	28162770	MOLM13	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	1.2240546227348765	[208]	[352]	8	hSpCas9	negative selection	11581266
85596585	85596608	2	+	28162770	MOLM13	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.08035357362507145	[432]	[330]	0	hSpCas9	negative selection	11581267
85596838	85596861	2	+	28162770	MOLM13	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	0.06030176397678422	[836]	[630]	0	hSpCas9	negative selection	11581268
85596881	85596904	2	-	28162770	MOLM13	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	-0.9915422370927187	[98]	[35]	-5	hSpCas9	negative selection	11581269
85596602	85596625	2	+	28162770	MOLM13	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	0.8751073763641234	[554]	[735]	6	hSpCas9	negative selection	11581270
85596870	85596893	2	-	28162770	MOLM13	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	1.0555560911941133	[532]	[800]	7	hSpCas9	negative selection	11581271
85596917	85596940	2	-	28162770	MOLM13	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.5046892997475307	[657]	[674]	4	hSpCas9	negative selection	11581272
85595781	85595804	2	+	28162770	MOLM13	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	0.401291632815555	[132]	[126]	3	hSpCas9	negative selection	11581273
85595793	85595816	2	+	28162770	MOLM13	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	-1.3504645394622823	[394]	[111]	-6	hSpCas9	negative selection	11581274
85595825	85595848	2	-	28162770	MOLM13	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	1.0375527458828526	[315]	[468]	7	hSpCas9	negative selection	11581275
85595817	85595840	2	+	28162770	HEL	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	0.8206205572710125	[220]	[249]	7	hSpCas9	negative selection	11750632
85596585	85596608	2	+	28162770	HEL	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.3042427857001519	[373]	[193]	-2	hSpCas9	negative selection	11750633
85596838	85596861	2	+	28162770	HEL	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	-0.8562211508235777	[813]	[287]	-5	hSpCas9	negative selection	11750634
85596881	85596904	2	-	28162770	HEL	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	0.5496294276088755	[111]	[104]	4	hSpCas9	negative selection	11750635
85596602	85596625	2	+	28162770	HEL	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	-0.39625529961550676	[449]	[218]	-3	hSpCas9	negative selection	11750636
85596870	85596893	2	-	28162770	HEL	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	0.22681542846224256	[542]	[406]	1	hSpCas9	negative selection	11750637
85596917	85596940	2	-	28162770	HEL	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.14096401074263154	[496]	[350]	1	hSpCas9	negative selection	11750638
85595781	85595804	2	+	28162770	HEL	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	1.0064294512789802	[142]	[183]	8	hSpCas9	negative selection	11750639
85595793	85595816	2	+	28162770	HEL	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	-0.28180893957017744	[297]	[156]	-2	hSpCas9	negative selection	11750640
85595825	85595848	2	-	28162770	HEL	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	-0.39031945657893874	[308]	[150]	-3	hSpCas9	negative selection	11750641
85595817	85595840	2	+	28162770	MV411	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	0.9980780818460578	[125]	[211]	8	hSpCas9	negative selection	11919998
85596585	85596608	2	+	28162770	MV411	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.1426413607711654	[313]	[291]	1	hSpCas9	negative selection	11919999
85596838	85596861	2	+	28162770	MV411	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	0.07121531087925326	[573]	[507]	0	hSpCas9	negative selection	11920000
85596881	85596904	2	-	28162770	MV411	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	0.6447730483281603	[81]	[107]	6	hSpCas9	negative selection	11920001
85596602	85596625	2	+	28162770	MV411	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	-0.3740508259634949	[459]	[298]	-3	hSpCas9	negative selection	11920002
85596870	85596893	2	-	28162770	MV411	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	0.37008246462902683	[416]	[453]	3	hSpCas9	negative selection	11920003
85596917	85596940	2	-	28162770	MV411	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.0687316637982529	[411]	[363]	0	hSpCas9	negative selection	11920004
85595781	85595804	2	+	28162770	MV411	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	-0.330329448534177	[99]	[66]	-2	hSpCas9	negative selection	11920005
85595793	85595816	2	+	28162770	MV411	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	-0.44301807878569494	[233]	[144]	-3	hSpCas9	negative selection	11920006
85595825	85595848	2	-	28162770	MV411	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	-0.04838679016868801	[177]	[144]	0	hSpCas9	negative selection	11920007
85595817	85595840	2	+	28162770	MONOMAC1	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	-0.2414309664180072	[98]	[95]	-2	hSpCas9	negative selection	12089364
85596585	85596608	2	+	28162770	MONOMAC1	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.6345656212447276	[235]	[419]	6	hSpCas9	negative selection	12089365
85596838	85596861	2	+	28162770	MONOMAC1	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	0.34497350847705555	[374]	[545]	3	hSpCas9	negative selection	12089366
85596881	85596904	2	-	28162770	MONOMAC1	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	0.4641612394886878	[42]	[67]	4	hSpCas9	negative selection	12089367
85596602	85596625	2	+	28162770	MONOMAC1	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	0.5388055901477151	[256]	[427]	5	hSpCas9	negative selection	12089368
85596870	85596893	2	-	28162770	MONOMAC1	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	0.7009422159999372	[248]	[463]	6	hSpCas9	negative selection	12089369
85596917	85596940	2	-	28162770	MONOMAC1	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.5239208709062604	[289]	[477]	5	hSpCas9	negative selection	12089370
85595781	85595804	2	+	28162770	MONOMAC1	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	-0.8838789617999235	[65]	[40]	-6	hSpCas9	negative selection	12089371
85595793	85595816	2	+	28162770	MONOMAC1	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	-1.5142270229402528	[151]	[60]	-8	hSpCas9	negative selection	12089372
85595825	85595848	2	-	28162770	MONOMAC1	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	0.6714583698119544	[131]	[240]	6	hSpCas9	negative selection	12089373
85595817	85595840	2	+	28162770	OCIAML2	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	0.45274889315492617	[28]	[219]	4	hSpCas9	negative selection	12258730
85596585	85596608	2	+	28162770	OCIAML2	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	0.44026270092385367	[47]	[360]	4	hSpCas9	negative selection	12258731
85596838	85596861	2	+	28162770	OCIAML2	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	0.18770586180921445	[114]	[725]	1	hSpCas9	negative selection	12258732
85596881	85596904	2	-	28162770	OCIAML2	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	0.3367250968154428	[15]	[111]	3	hSpCas9	negative selection	12258733
85596602	85596625	2	+	28162770	OCIAML2	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	-0.27561384283701823	[56]	[260]	-2	hSpCas9	negative selection	12258734
85596870	85596893	2	-	28162770	OCIAML2	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	0.49818851950955945	[75]	[594]	5	hSpCas9	negative selection	12258735
85596917	85596940	2	-	28162770	OCIAML2	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	0.2391391312152753	[82]	[542]	2	hSpCas9	negative selection	12258736
85595781	85595804	2	+	28162770	OCIAML2	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	0.4201411050030803	[23]	[177]	4	hSpCas9	negative selection	12258737
85595793	85595816	2	+	28162770	OCIAML2	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	-0.4897386481898657	[37]	[149]	-4	hSpCas9	negative selection	12258738
85595825	85595848	2	-	28162770	OCIAML2	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	-0.10450192644426398	[44]	[231]	-1	hSpCas9	negative selection	12258739
85595817	85595840	2	+	28162770	OCIAML3	viability	GACGCGAACCAACATGCTGCTGG	RNF181	ENSG00000168894	-0.12007645199175088	[26]	[74]	-1	hSpCas9	negative selection	12428096
85596585	85596608	2	+	28162770	OCIAML3	viability	TCCACCAGCTGCCAAGACTGTGG	RNF181	ENSG00000168894	-0.3299001998251433	[111]	[268]	-3	hSpCas9	negative selection	12428097
85596838	85596861	2	+	28162770	OCIAML3	viability	GTGTCTTTTGGAATTTGAGGAGG	RNF181	ENSG00000168894	0.7978359131644477	[144]	[760]	7	hSpCas9	negative selection	12428098
85596881	85596904	2	-	28162770	OCIAML3	viability	GAATGGAAAAGGTGATGGCAAGG	RNF181	ENSG00000168894	-1.5940076403241632	[30]	[30]	-8	hSpCas9	negative selection	12428099
85596602	85596625	2	+	28162770	OCIAML3	viability	CTGTGGTTGAGAACCTCCCCAGG	RNF181	ENSG00000168894	0.6729539953452703	[106]	[514]	6	hSpCas9	negative selection	12428100
85596870	85596893	2	-	28162770	OCIAML3	viability	GTGATGGCAAGGCATCTCAATGG	RNF181	ENSG00000168894	0.48362977107010274	[103]	[438]	4	hSpCas9	negative selection	12428101
85596917	85596940	2	-	28162770	OCIAML3	viability	AGCAGTACCTTGCTTAGCCAGGG	RNF181	ENSG00000168894	-0.18504465545500381	[118]	[315]	-1	hSpCas9	negative selection	12428102
85595781	85595804	2	+	28162770	OCIAML3	viability	TGAACACGACTGCGAGCCGTCGG	RNF181	ENSG00000168894	0.1684930459491807	[27]	[94]	1	hSpCas9	negative selection	12428103
85595793	85595816	2	+	28162770	OCIAML3	viability	CGAGCCGTCGGACCCTGAGCAGG	RNF181	ENSG00000168894	0.08059207288166959	[103]	[331]	0	hSpCas9	negative selection	12428104
85595825	85595848	2	-	28162770	OCIAML3	viability	TGCGAGCTCCAGCAGCATGTTGG	RNF181	ENSG00000168894	1.8465649510618183	[48]	[531]	9	hSpCas9	negative selection	12428105