Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 643596
• Symbol: RNF224
• Description: ring finger protein 224

DataSource: http://genomecrispr.dkfz.de/#!/results/RNF224

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
137228732	137228755	9	-	26472758	Jiyoye	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	-0.6319952157748044	[223]	[108]	-4	hSpCas9	negative selection	138371
137229060	137229083	9	-	26472758	Jiyoye	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	3.214530303563477	[0]	[6]	9	hSpCas9	negative selection	138372
137228755	137228778	9	+	26472758	Jiyoye	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	0.7152976768682052	[62]	[77]	5	hSpCas9	negative selection	138373
137228665	137228688	9	-	26472758	Jiyoye	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.5794662356391076	[429]	[216]	-4	hSpCas9	negative selection	138374
137228810	137228833	9	-	26472758	Jiyoye	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	1.5090549955250872	[81]	[175]	8	hSpCas9	negative selection	138375
137228844	137228867	9	-	26472758	Jiyoye	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	0.5081042903566542	[206]	[221]	4	hSpCas9	negative selection	138376
137228858	137228881	9	+	26472758	Jiyoye	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	-0.7274741451889085	[302]	[137]	-5	hSpCas9	negative selection	138377
137228928	137228951	9	-	26472758	Jiyoye	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	-0.146760223594658	[68]	[46]	-1	hSpCas9	negative selection	138378
137228992	137229015	9	-	26472758	Jiyoye	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	-1.4900650440689258	[148]	[39]	-7	hSpCas9	negative selection	138379
137229015	137229038	9	-	26472758	Jiyoye	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	-1.4838902469409627	[203]	[54]	-7	hSpCas9	negative selection	138380
137228732	137228755	9	-	26472758	KBM7	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	1.1816628745157256	[595,374]	[738,301]	9	hSpCas9	negative selection	329489
137229060	137229083	9	-	26472758	KBM7	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	-0.5101931626781449	[19,2]	[2,3]	-4	hSpCas9	negative selection	329490
137228755	137228778	9	+	26472758	KBM7	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	0.7546111717665794	[333,275]	[244,236]	8	hSpCas9	negative selection	329491
137228665	137228688	9	-	26472758	KBM7	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.1355490024236543	[1514,840]	[672,329]	-1	hSpCas9	negative selection	329492
137228810	137228833	9	-	26472758	KBM7	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	-0.3356546975582716	[772,529]	[280,201]	-3	hSpCas9	negative selection	329493
137228844	137228867	9	-	26472758	KBM7	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	0.5220994742932699	[811,425]	[431,383]	5	hSpCas9	negative selection	329494
137228858	137228881	9	+	26472758	KBM7	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	0.40771443636268023	[764,444]	[236,486]	4	hSpCas9	negative selection	329495
137228928	137228951	9	-	26472758	KBM7	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	-0.05262304712623178	[366,229]	[211,61]	0	hSpCas9	negative selection	329496
137228992	137229015	9	-	26472758	KBM7	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	-0.47150722445527693	[600,324]	[124,177]	-4	hSpCas9	negative selection	329497
137229015	137229038	9	-	26472758	KBM7	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.3135044281811871	[511,393]	[234,286]	3	hSpCas9	negative selection	329498
137228732	137228755	9	-	26472758	Raji	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	-0.08330002623551028	[209]	[45]	0	hSpCas9	negative selection	520607
137229060	137229083	9	-	26472758	Raji	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	520608
137228755	137228778	9	+	26472758	Raji	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	0.03462719293828509	[121]	[28]	0	hSpCas9	negative selection	520609
137228665	137228688	9	-	26472758	Raji	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-1.5298352024789805	[758]	[60]	-8	hSpCas9	negative selection	520610
137228810	137228833	9	-	26472758	Raji	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	1.1073835353735995	[195]	[97]	8	hSpCas9	negative selection	520611
137228844	137228867	9	-	26472758	Raji	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	0.36914178452012303	[376]	[112]	3	hSpCas9	negative selection	520612
137228858	137228881	9	+	26472758	Raji	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	-0.4161784206834136	[321]	[55]	-3	hSpCas9	negative selection	520613
137228928	137228951	9	-	26472758	Raji	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	0.37041794120739313	[99]	[29]	3	hSpCas9	negative selection	520614
137228992	137229015	9	-	26472758	Raji	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	-0.625332585791249	[225]	[33]	-5	hSpCas9	negative selection	520615
137229015	137229038	9	-	26472758	Raji	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.17074559637102885	[244]	[63]	1	hSpCas9	negative selection	520616
137228732	137228755	9	-	26472758	K562	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	0.0834468084568219	[501]	[448]	0	hSpCas9	negative selection	711725
137229060	137229083	9	-	26472758	K562	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	-1.7555812723335524	[3]	[0]	-7	hSpCas9	negative selection	711726
137228755	137228778	9	+	26472758	K562	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	1.207660177656329	[317]	[619]	8	hSpCas9	negative selection	711727
137228665	137228688	9	-	26472758	K562	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-1.5308109123659681	[865]	[252]	-6	hSpCas9	negative selection	711728
137228810	137228833	9	-	26472758	K562	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	-0.03363786878499986	[501]	[413]	0	hSpCas9	negative selection	711729
137228844	137228867	9	-	26472758	K562	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	0.8067695314872316	[492]	[727]	6	hSpCas9	negative selection	711730
137228858	137228881	9	+	26472758	K562	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	0.4974654070451955	[458]	[546]	4	hSpCas9	negative selection	711731
137228928	137228951	9	-	26472758	K562	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	0.35294318444461587	[255]	[275]	2	hSpCas9	negative selection	711732
137228992	137229015	9	-	26472758	K562	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	-0.928912875219115	[317]	[140]	-5	hSpCas9	negative selection	711733
137229015	137229038	9	-	26472758	K562	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.2968861475605824	[377]	[391]	2	hSpCas9	negative selection	711734
137228616	137228639	9	+	26627737	DLD1	viability	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.7378990745688594	[398]	[93,51,76]	-6	hSpCas9	negative selection	842314
137228768	137228791	9	+	26627737	DLD1	viability	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.17952072150866205	[439]	[190,149,129]	1	hSpCas9	negative selection	842315
137228876	137228899	9	-	26627737	DLD1	viability	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	0.35049213429711357	[379]	[75,236,145]	3	hSpCas9	negative selection	842316
137228888	137228911	9	+	26627737	DLD1	viability	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	0.03821335336930742	[210]	[148,55,6]	0	hSpCas9	negative selection	842317
137228958	137228981	9	+	26627737	DLD1	viability	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	0.2545335041298453	[610]	[243,281,168]	2	hSpCas9	negative selection	842318
137228616	137228639	9	+	26627737	GBM cells	viability after 5 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.42301422000167677	[214]	[65,105]	-6	hSpCas9	negative selection	924629
137228768	137228791	9	+	26627737	GBM cells	viability after 5 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	-0.5972393588776148	[188]	[55,77]	-7	hSpCas9	negative selection	924630
137228876	137228899	9	-	26627737	GBM cells	viability after 5 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	0.15952561845262364	[297]	[200,155]	2	hSpCas9	negative selection	924631
137228888	137228911	9	+	26627737	GBM cells	viability after 5 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	0.14449108364293295	[96]	[58,55]	2	hSpCas9	negative selection	924632
137228958	137228981	9	+	26627737	GBM cells	viability after 5 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	0.3201565236912375	[173]	[114,117]	5	hSpCas9	negative selection	924633
137228616	137228639	9	+	26627737	GBM cells	viability after 13 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.6037184758041053	[214]	[89,65]	-6	hSpCas9	negative selection	1006944
137228768	137228791	9	+	26627737	GBM cells	viability after 13 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.0122197903090977	[188]	[114,93]	0	hSpCas9	negative selection	1006945
137228876	137228899	9	-	26627737	GBM cells	viability after 13 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	-0.011296999009513309	[297]	[187,137]	0	hSpCas9	negative selection	1006946
137228888	137228911	9	+	26627737	GBM cells	viability after 13 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	0.7648203143290356	[96]	[116,66]	8	hSpCas9	negative selection	1006947
137228958	137228981	9	+	26627737	GBM cells	viability after 13 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	-0.8077219629598681	[173]	[59,48]	-7	hSpCas9	negative selection	1006948
137228616	137228639	9	+	26627737	GBM cells	viability after 21 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.140644125841315	[214]	[106,104]	-1	hSpCas9	negative selection	1089259
137228768	137228791	9	+	26627737	GBM cells	viability after 21 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	-0.33603721173839446	[188]	[84,77]	-3	hSpCas9	negative selection	1089260
137228876	137228899	9	-	26627737	GBM cells	viability after 21 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	0.6644421393558171	[297]	[265,247]	6	hSpCas9	negative selection	1089261
137228888	137228911	9	+	26627737	GBM cells	viability after 21 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	0.17136152999099052	[96]	[62,55]	1	hSpCas9	negative selection	1089262
137228958	137228981	9	+	26627737	GBM cells	viability after 21 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	0.7010545560481585	[173]	[172,135]	7	hSpCas9	negative selection	1089263
137228616	137228639	9	+	26627737	RPE1	viability after 9 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.2693028208339241	[148]	[46,27]	-2	hSpCas9	negative selection	1171574
137228768	137228791	9	+	26627737	RPE1	viability after 9 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	-0.3820725087625314	[1048]	[282,211]	-3	hSpCas9	negative selection	1171575
137228876	137228899	9	-	26627737	RPE1	viability after 9 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	0.2897548628381511	[1190]	[388,541]	2	hSpCas9	negative selection	1171576
137228888	137228911	9	+	26627737	RPE1	viability after 9 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	0.6316437863506281	[291]	[114,175]	4	hSpCas9	negative selection	1171577
137228958	137228981	9	+	26627737	RPE1	viability after 9 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	2.013058664874116	[417]	[477,592]	8	hSpCas9	negative selection	1171578
137228616	137228639	9	+	26627737	RPE1	viability after 12 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-1.551473317753242	[148]	[18,7]	-8	hSpCas9	negative selection	1253889
137228768	137228791	9	+	26627737	RPE1	viability after 12 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	-0.40649589272332376	[1048]	[318,99]	-3	hSpCas9	negative selection	1253890
137228876	137228899	9	-	26627737	RPE1	viability after 12 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	-0.28842328465352574	[1190]	[312,207]	-2	hSpCas9	negative selection	1253891
137228888	137228911	9	+	26627737	RPE1	viability after 12 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	-0.2988748523226583	[291]	[55,71]	-2	hSpCas9	negative selection	1253892
137228958	137228981	9	+	26627737	RPE1	viability after 12 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	1.8218513013576816	[417]	[601,179]	8	hSpCas9	negative selection	1253893
137228616	137228639	9	+	26627737	RPE1	viability after 15 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-5.397419646590268	[148]	[0,0]	-9	hSpCas9	negative selection	1336204
137228768	137228791	9	+	26627737	RPE1	viability after 15 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	-0.09244274743867764	[1048]	[428,132]	0	hSpCas9	negative selection	1336205
137228876	137228899	9	-	26627737	RPE1	viability after 15 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	-0.3718212463582122	[1190]	[267,252]	-2	hSpCas9	negative selection	1336206
137228888	137228911	9	+	26627737	RPE1	viability after 15 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	0.5697607822738371	[291]	[144,100]	3	hSpCas9	negative selection	1336207
137228958	137228981	9	+	26627737	RPE1	viability after 15 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	1.6711471861448834	[417]	[400,352]	8	hSpCas9	negative selection	1336208
137228616	137228639	9	+	26627737	RPE1	viability after 18 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-1.5167830596352383	[148]	[0,27]	-7	hSpCas9	negative selection	1418519
137228768	137228791	9	+	26627737	RPE1	viability after 18 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	-0.7837065829006518	[1048]	[220,103]	-5	hSpCas9	negative selection	1418520
137228876	137228899	9	-	26627737	RPE1	viability after 18 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	-0.11885917170196852	[1190]	[222,373]	0	hSpCas9	negative selection	1418521
137228888	137228911	9	+	26627737	RPE1	viability after 18 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	0.5685711871689723	[291]	[112,120]	3	hSpCas9	negative selection	1418522
137228958	137228981	9	+	26627737	RPE1	viability after 18 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	1.6798110132107227	[417]	[591,114]	8	hSpCas9	negative selection	1418523
137228616	137228639	9	+	26627737	HeLa	viability after 8 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-1.6324065318176353	[691]	[108,13,165]	-9	hSpCas9	negative selection	1500834
137228768	137228791	9	+	26627737	HeLa	viability after 8 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.26111660583020474	[410]	[174,269,190]	2	hSpCas9	negative selection	1500835
137228876	137228899	9	-	26627737	HeLa	viability after 8 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	-0.4998932831665651	[428]	[107,124,155]	-5	hSpCas9	negative selection	1500836
137228888	137228911	9	+	26627737	HeLa	viability after 8 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	1.39036505236516	[113]	[78,141,155]	8	hSpCas9	negative selection	1500837
137228958	137228981	9	+	26627737	HeLa	viability after 8 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	-0.5187209348345497	[371]	[161,48,136]	-5	hSpCas9	negative selection	1500838
137228616	137228639	9	+	26627737	HeLa	viability after 12 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-1.4718657781821167	[691]	[139,49,125]	-8	hSpCas9	negative selection	1583149
137228768	137228791	9	+	26627737	HeLa	viability after 12 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.09701730499936262	[410]	[234,167,144]	0	hSpCas9	negative selection	1583150
137228876	137228899	9	-	26627737	HeLa	viability after 12 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	0.042722380330876636	[428]	[266,43,253]	0	hSpCas9	negative selection	1583151
137228888	137228911	9	+	26627737	HeLa	viability after 12 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	0.5053624182007919	[113]	[38,83,74]	4	hSpCas9	negative selection	1583152
137228958	137228981	9	+	26627737	HeLa	viability after 12 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	-0.5855843980062284	[371]	[34,105,163]	-5	hSpCas9	negative selection	1583153
137228616	137228639	9	+	26627737	HeLa	viability after 15 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-2.756046979304776	[691]	[58,58,3]	-9	hSpCas9	negative selection	1665464
137228768	137228791	9	+	26627737	HeLa	viability after 15 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.5951728479114669	[410]	[211,327,215]	5	hSpCas9	negative selection	1665465
137228876	137228899	9	-	26627737	HeLa	viability after 15 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	-0.409248104237417	[428]	[211,55,124]	-4	hSpCas9	negative selection	1665466
137228888	137228911	9	+	26627737	HeLa	viability after 15 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	1.4156717459564385	[113]	[82,200,84]	8	hSpCas9	negative selection	1665467
137228958	137228981	9	+	26627737	HeLa	viability after 15 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	0.20737881155126314	[371]	[179,78,272]	1	hSpCas9	negative selection	1665468
137228616	137228639	9	+	26627737	HeLa	viability after 18 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-2.800657718199583	[691]	[40,43,3]	-9	hSpCas9	negative selection	1747779
137228768	137228791	9	+	26627737	HeLa	viability after 18 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.6450101256240843	[410]	[143,290,215]	5	hSpCas9	negative selection	1747780
137228876	137228899	9	-	26627737	HeLa	viability after 18 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	-0.37988811187428917	[428]	[146,46,124]	-3	hSpCas9	negative selection	1747781
137228888	137228911	9	+	26627737	HeLa	viability after 18 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	1.4142524187181005	[113]	[58,161,84]	8	hSpCas9	negative selection	1747782
137228958	137228981	9	+	26627737	HeLa	viability after 18 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	0.23633155444221257	[371]	[123,69,272]	2	hSpCas9	negative selection	1747783
137228616	137228639	9	+	26627737	HCT116	viability after 6 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	2.044876222968918	[439]	[530,149]	8	hSpCas9	negative selection	1830094
137228768	137228791	9	+	26627737	HCT116	viability after 6 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.9199783007096735	[713]	[339,141]	5	hSpCas9	negative selection	1830095
137228876	137228899	9	-	26627737	HCT116	viability after 6 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	0.6925206628406881	[460]	[42,157]	4	hSpCas9	negative selection	1830096
137228888	137228911	9	+	26627737	HCT116	viability after 6 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	0.31063751197079215	[320]	[137,20]	1	hSpCas9	negative selection	1830097
137228958	137228981	9	+	26627737	HCT116	viability after 6 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	0.4202877599660463	[287]	[135,18]	2	hSpCas9	negative selection	1830098
137228616	137228639	9	+	26627737	HCT116	viability after 8 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.3947157086770433	[478]	[166,176,256]	-5	hSpCas9	negative selection	1912409
137228768	137228791	9	+	26627737	HCT116	viability after 8 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.3775364076475344	[248]	[103,216,211]	4	hSpCas9	negative selection	1912410
137228876	137228899	9	-	26627737	HCT116	viability after 8 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	0.30452261265308317	[278]	[251,152,165]	3	hSpCas9	negative selection	1912411
137228888	137228911	9	+	26627737	HCT116	viability after 8 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	1.7520348689860075	[56]	[134,84,97]	9	hSpCas9	negative selection	1912412
137228958	137228981	9	+	26627737	HCT116	viability after 8 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	0.24474745374411855	[160]	[96,95,121]	2	hSpCas9	negative selection	1912413
137228616	137228639	9	+	26627737	HCT116	viability after 9 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	0.705407465991829	[439]	[228,161]	5	hSpCas9	negative selection	1994724
137228768	137228791	9	+	26627737	HCT116	viability after 9 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.4663013448931719	[713]	[292,239]	3	hSpCas9	negative selection	1994725
137228876	137228899	9	-	26627737	HCT116	viability after 9 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	1.2496147228280052	[460]	[390,214]	8	hSpCas9	negative selection	1994726
137228888	137228911	9	+	26627737	HCT116	viability after 9 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	0.7854646803819603	[320]	[154,141]	5	hSpCas9	negative selection	1994727
137228958	137228981	9	+	26627737	HCT116	viability after 9 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	1.2083134810621694	[287]	[213,148]	7	hSpCas9	negative selection	1994728
137228616	137228639	9	+	26627737	HCT116	viability after 12 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.4103945200213624	[478]	[237,67,254]	-4	hSpCas9	negative selection	2077039
137228768	137228791	9	+	26627737	HCT116	viability after 12 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.4192386195437343	[248]	[147,202,176]	4	hSpCas9	negative selection	2077040
137228876	137228899	9	-	26627737	HCT116	viability after 12 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	0.6652228766863376	[278]	[341,152,190]	6	hSpCas9	negative selection	2077041
137228888	137228911	9	+	26627737	HCT116	viability after 12 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	1.3975763044088712	[56]	[68,52,114]	9	hSpCas9	negative selection	2077042
137228958	137228981	9	+	26627737	HCT116	viability after 12 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	0.9330724866498354	[160]	[189,72,216]	7	hSpCas9	negative selection	2077043
137228616	137228639	9	+	26627737	HCT116	viability after 15 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.4917358676594101	[478]	[106,263,204]	-5	hSpCas9	negative selection	2159354
137228768	137228791	9	+	26627737	HCT116	viability after 15 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.46879405784564354	[248]	[212,221,160]	4	hSpCas9	negative selection	2159355
137228876	137228899	9	-	26627737	HCT116	viability after 15 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	1.098825223012161	[278]	[436,264,338]	8	hSpCas9	negative selection	2159356
137228888	137228911	9	+	26627737	HCT116	viability after 15 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	2.2501962603616623	[56]	[164,119,182]	9	hSpCas9	negative selection	2159357
137228958	137228981	9	+	26627737	HCT116	viability after 15 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	0.8013667023253126	[160]	[44,156,265]	7	hSpCas9	negative selection	2159358
137228616	137228639	9	+	26627737	HCT116	viability after 18 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.5858458987243869	[478]	[28,195,238]	-5	hSpCas9	negative selection	2241669
137228768	137228791	9	+	26627737	HCT116	viability after 18 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	1.0775576681440429	[248]	[138,473,128]	8	hSpCas9	negative selection	2241670
137228876	137228899	9	-	26627737	HCT116	viability after 18 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	0.9580941341099402	[278]	[391,166,231]	7	hSpCas9	negative selection	2241671
137228888	137228911	9	+	26627737	HCT116	viability after 18 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	1.8495881314066445	[56]	[93,100,102]	9	hSpCas9	negative selection	2241672
137228958	137228981	9	+	26627737	HCT116	viability after 18 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	1.038731337352371	[160]	[64,127,294]	7	hSpCas9	negative selection	2241673
137227403	137227426	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGTGGGCAGGGGTGAGGAGGGG	RNF224	ENSG00000233198	-2.0838639061257185	[2,168]	[2,4]	-9	dCas9-VP64	positive selection	2408367
137227444	137227467	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGGCTGTGAGTGGTTCTGGGG	RNF224	ENSG00000233198	-0.07444929346390683	[198,54]	[9,42]	0	dCas9-VP64	positive selection	2408368
137227377	137227400	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGCAGTCTGCCCCCAGGACTGG	RNF224	ENSG00000233198	-0.65011170900639	[40,60]	[5,6]	-3	dCas9-VP64	positive selection	2408369
137227403	137227426	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGTGGGCAGGGGTGAGGAGGGG	RNF224	ENSG00000233198	0.7489975817765555	[80,84]	[59,31]	5	dCas9-VP64	positive selection	2503622
137227444	137227467	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGGCTGTGAGTGGTTCTGGGG	RNF224	ENSG00000233198	1.5167040773316245	[13,28]	[9,29]	8	dCas9-VP64	positive selection	2503623
137227377	137227400	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGCAGTCTGCCCCCAGGACTGG	RNF224	ENSG00000233198	-0.48702250902949873	[115,290]	[42,49]	-5	dCas9-VP64	positive selection	2503624
137228732	137228755	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	0.42896445516956205	[3,3]	[3,4]	8	hSpCas9	positive selection	3017332
137228665	137228688	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.1140044154250095	[4,5]	[3,3]	-2	hSpCas9	positive selection	3017333
137228618	137228641	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCAGGATGCTGCAGCCGGAGGG	RNF224	ENSG00000233198	-0.12393449043650642	[3,2]	[1,2]	-2	hSpCas9	positive selection	3017334
137228756	137228779	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	-0.13201687522568312	[3,3]	[3,1]	-2	hSpCas9	positive selection	3017335
137228732	137228755	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	0.36265588021212225	[3,3]	[5,1]	6	hSpCas9	positive selection	3085190
137228665	137228688	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	0.03164047444119744	[4,4]	[6,1]	0	hSpCas9	positive selection	3085191
137228618	137228641	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCAGGATGCTGCAGCCGGAGGG	RNF224	ENSG00000233198	-0.6330805681275884	[3,3]	[2,0]	-8	hSpCas9	positive selection	3085192
137228756	137228779	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	-0.4605455169016708	[3,3]	[2,0]	-6	hSpCas9	positive selection	3085193
137228829	137228852		+	24336571	A375	resistance to PLX after 7 days	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.1963743561586024	[12,14]	[15,15]	6	hSpCas9	positive selection	3141387
137228825	137228848		-	24336571	A375	resistance to PLX after 7 days	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.1075000203454308	[15,16]	[16,12]	-3	hSpCas9	positive selection	3141388
137228829	137228852		+	24336571	A375	resistance to PLX after 14 days	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.05499924689807573	[11,14]	[5,5]	0	hSpCas9	positive selection	3199180
137228825	137228848		-	24336571	A375	resistance to PLX after 14 days	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.23943366737507296	[13,15]	[4,6]	-3	hSpCas9	positive selection	3199181
137228829	137228852		+	24336571	A375	viability after 7 days	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.4757450972889975	[10]	[12,14]	7	hSpCas9	negative selection	3256973
137228825	137228848		-	24336571	A375	viability after 7 days	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.9013305814232996	[8]	[15,16]	9	hSpCas9	negative selection	3256974
137228829	137228852		+	24336571	A375	viability after 14 days	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.44085692947378285	[10]	[11,14]	5	hSpCas9	negative selection	3314766
137228825	137228848		-	24336571	A375	viability after 14 days	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.8177613395760249	[8]	[13,15]	8	hSpCas9	negative selection	3314767
137228759	137228782	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	-1.3573836326693731	[391,391]	[0,0]	-8	hSpCas9	positive selection	3390208
137228785	137228808	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	0.8143827155971068	[86,86]	[0,0]	4	hSpCas9	positive selection	3390209
137228852	137228875	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.6851882938934047	[245,245]	[0,0]	-5	hSpCas9	positive selection	3390210
137228732	137228755	9	-	26780180	HT29	viability (Avana library 4 designs)	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	0.723949898137506	[]	[]	2	hSpCas9	negative selection	3455711
137228665	137228688	9	-	26780180	HT29	viability (Avana library 4 designs)	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	0.813416898023886	[]	[]	3	hSpCas9	negative selection	3455712
137228617	137228640	9	+	26780180	HT29	viability (Avana library 4 designs)	GGCAGGATGCTGCAGCCGGAGGG	RNF224	ENSG00000233198	2.49337399204827	[]	[]	8	hSpCas9	negative selection	3455713
137228755	137228778	9	+	26780180	HT29	viability (Avana library 4 designs)	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	2.17591462886195	[]	[]	7	hSpCas9	negative selection	3455714
137228617	137228640	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCAGGATGCTGCAGCCGGAGGG	RNF224	ENSG00000233198	4.81933446158134	[]	[]	7	hSpCas9	negative selection	3553829
137228732	137228755	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	3.53174008647804	[]	[]	5	hSpCas9	negative selection	3553830
137228665	137228688	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	2.77629980283098	[]	[]	4	hSpCas9	negative selection	3553831
137228755	137228778	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	2.69664599256402	[]	[]	4	hSpCas9	negative selection	3553832
137228829	137228852	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.679425774111603	[]	[]	0	hSpCas9	negative selection	3553833
137228727	137228750	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	5.76688001265423	[]	[]	9	hSpCas9	negative selection	3553834
137228617	137228640	9	+	26780180	A375	viability (Avana lentiGuide)	GGCAGGATGCTGCAGCCGGAGGG	RNF224	ENSG00000233198	1.82340221782704	[]	[]	2	hSpCas9	negative selection	3662488
137228732	137228755	9	-	26780180	A375	viability (Avana lentiGuide)	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	-0.788013553705475	[]	[]	-1	hSpCas9	negative selection	3662489
137228665	137228688	9	-	26780180	A375	viability (Avana lentiGuide)	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	3.78317904916061	[]	[]	3	hSpCas9	negative selection	3662490
137228755	137228778	9	+	26780180	A375	viability (Avana lentiGuide)	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	3.57047204809055	[]	[]	3	hSpCas9	negative selection	3662491
137228829	137228852	9	+	26780180	A375	viability (Avana lentiGuide)	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-2.05315709816846	[]	[]	-3	hSpCas9	negative selection	3662492
137228727	137228750	9	-	26780180	A375	viability (Avana lentiGuide)	TGTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	2.02337118467271	[]	[]	2	hSpCas9	negative selection	3662493
137228617	137228640	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCAGGATGCTGCAGCCGGAGGG	RNF224	ENSG00000233198	0.07272238846237139	[3]	[3,3]	1	hSpCas9	positive selection	3771095
137228732	137228755	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	0.012426550673669845	[4]	[4,4]	0	hSpCas9	positive selection	3771096
137228665	137228688	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.08915658515192894	[5]	[6,4]	-1	hSpCas9	positive selection	3771097
137228755	137228778	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	0.19938556398580348	[5]	[5,5]	5	hSpCas9	positive selection	3771098
137228829	137228852	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.2011001059103079	[3]	[4,4]	5	hSpCas9	positive selection	3771099
137228727	137228750	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	0.40105741596406763	[4]	[5,5]	9	hSpCas9	positive selection	3771100
137228617	137228640	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCAGGATGCTGCAGCCGGAGGG	RNF224	ENSG00000233198	0.159871289708168	[4]	[4,5]	4	hSpCas9	positive selection	3879702
137228732	137228755	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	-0.25480170777432676	[5]	[3,2]	-3	hSpCas9	positive selection	3879703
137228665	137228688	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.05598615060908829	[7]	[5,5]	-1	hSpCas9	positive selection	3879704
137228755	137228778	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	0.08145432687992836	[5]	[4,5]	1	hSpCas9	positive selection	3879705
137228829	137228852	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.09308878344772521	[5]	[4,2]	-1	hSpCas9	positive selection	3879706
137228727	137228750	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	-0.2024610494191923	[5]	[3,3]	-3	hSpCas9	positive selection	3879707
137228852	137228875	9	+	26780180	A375	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	1.58184701350332	[]	[]	8	hSpCas9	negative selection	3989816
137228785	137228808	9	+	26780180	A375	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	1.38277499457336	[]	[]	7	hSpCas9	negative selection	3989817
137228829	137228852	9	+	26780180	A375	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	1.18816417968729	[]	[]	6	hSpCas9	negative selection	3989818
137228759	137228782	9	-	26780180	A375	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.688485480666328	[]	[]	2	hSpCas9	negative selection	3989819
137228825	137228848	9	-	26780180	A375	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	1.56837570300755	[]	[]	8	hSpCas9	negative selection	3989820
137228879	137228902	9	+	26780180	A375	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	0.787624893671542	[]	[]	3	hSpCas9	negative selection	3989821
137228852	137228875	9	+	26780180	HT29	viability (GeCKOv2 library)	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	2.10091441394007	[]	[]	9	hSpCas9	negative selection	4097782
137228785	137228808	9	+	26780180	HT29	viability (GeCKOv2 library)	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	1.50868824276975	[]	[]	7	hSpCas9	negative selection	4097783
137228829	137228852	9	+	26780180	HT29	viability (GeCKOv2 library)	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.266634082175366	[]	[]	0	hSpCas9	negative selection	4097784
137228759	137228782	9	-	26780180	HT29	viability (GeCKOv2 library)	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	1.5206912084466	[]	[]	7	hSpCas9	negative selection	4097785
137228825	137228848	9	-	26780180	HT29	viability (GeCKOv2 library)	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	1.22543353792321	[]	[]	6	hSpCas9	negative selection	4097786
137228879	137228902	9	+	26780180	HT29	viability (GeCKOv2 library)	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	0.926448156299998	[]	[]	4	hSpCas9	negative selection	4097787
137228829	137228852	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.028537164284763467	[3]	[2,2]	0	hSpCas9	positive selection	4166925
137228825	137228848	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.1176668129800768	[4]	[3,2]	3	hSpCas9	positive selection	4166926
137228829	137228852	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.2556289064523385	[4]	[4,0,0,0]	-4	hSpCas9	positive selection	4230947
137228825	137228848	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.4590643618306805	[4]	[1,1,0,3]	3	hSpCas9	positive selection	4230948
137228825	137228848	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.3331349588611035	[3]	[2,1]	-6	hSpCas9	positive selection	4295280
137228829	137228852	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.4163066555454804	[4]	[4,4]	8	hSpCas9	positive selection	4295281
137228879	137228902	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.6042998944096264	[1]	[1,0]	-8	hSpCas9	positive selection	4295282
137228759	137228782	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.1978476625462709	[3]	[3,2]	4	hSpCas9	positive selection	4359534
137228785	137228808	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.5590826016490835	[2]	[1,0]	-8	hSpCas9	positive selection	4359535
137228852	137228875	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.04973012998753303	[3]	[2,2]	-1	hSpCas9	positive selection	4359536
137228727	137228749	9	-	27760321	OCIAML3	viability	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	-0.08021149463140809	[956,735]	[519,753]	-1	hSpCas9	negative selection	4435283
137228793	137228815	9	-	27760321	OCIAML3	viability	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	0.08316369821069325	[774,574]	[476,654]	1	hSpCas9	negative selection	4435284
137228817	137228839	9	-	27760321	OCIAML3	viability	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	-0.1398321834844285	[723,668]	[460,537]	-1	hSpCas9	negative selection	4435285
137228834	137228856	9	+	27760321	OCIAML3	viability	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	0.11540071179959066	[745,614]	[572,574]	1	hSpCas9	negative selection	4435286
137228860	137228882	9	-	27760321	OCIAML3	viability	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	0.2960423420111489	[866,712]	[698,827]	3	hSpCas9	negative selection	4435287
137228727	137228749	9	-	27760321	OCIAML2	viability	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	-0.17929325425885845	[956,735]	[623,568]	-2	hSpCas9	negative selection	4518746
137228793	137228815	9	-	27760321	OCIAML2	viability	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	0.24958985921338317	[774,574]	[519,805]	3	hSpCas9	negative selection	4518747
137228817	137228839	9	-	27760321	OCIAML2	viability	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	0.26968025512017846	[723,668]	[658,705]	3	hSpCas9	negative selection	4518748
137228834	137228856	9	+	27760321	OCIAML2	viability	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	-0.05984369602688289	[745,614]	[507,548]	-1	hSpCas9	negative selection	4518749
137228860	137228882	9	-	27760321	OCIAML2	viability	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	0.11334474338924583	[866,712]	[596,807]	1	hSpCas9	negative selection	4518750
137228727	137228749	9	-	27760321	MV411	viability	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	-0.7852285985152808	[956,735]	[234,451]	-5	hSpCas9	negative selection	4602209
137228793	137228815	9	-	27760321	MV411	viability	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	0.9284459340750411	[774,574]	[880,778]	6	hSpCas9	negative selection	4602210
137228817	137228839	9	-	27760321	MV411	viability	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	0.49639872117607164	[723,668]	[659,630]	3	hSpCas9	negative selection	4602211
137228834	137228856	9	+	27760321	MV411	viability	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	-0.06631227253948624	[745,614]	[316,591]	0	hSpCas9	negative selection	4602212
137228860	137228882	9	-	27760321	MV411	viability	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	1.057282940632068	[866,712]	[1510,431]	7	hSpCas9	negative selection	4602213
137228727	137228749	9	-	27760321	HL60	viability	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	0.13040292587311975	[956,735]	[544,969]	1	hSpCas9	negative selection	4685672
137228793	137228815	9	-	27760321	HL60	viability	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	-0.03558134300448523	[774,574]	[472,596]	0	hSpCas9	negative selection	4685673
137228817	137228839	9	-	27760321	HL60	viability	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	-0.4638730651518381	[723,668]	[396,428]	-5	hSpCas9	negative selection	4685674
137228834	137228856	9	+	27760321	HL60	viability	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	0.06019945345975952	[745,614]	[473,685]	0	hSpCas9	negative selection	4685675
137228860	137228882	9	-	27760321	HL60	viability	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	0.2544994437383701	[866,712]	[689,846]	3	hSpCas9	negative selection	4685676
137228727	137228749	9	-	27760321	HT1080	viability	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	-0.7445153864374993	[735,574]	[247,54]	-3	hSpCas9	negative selection	4769135
137228793	137228815	9	-	27760321	HT1080	viability	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	-1.0443968506279577	[574,448]	[43,158]	-4	hSpCas9	negative selection	4769136
137228817	137228839	9	-	27760321	HT1080	viability	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	0.1545042029133179	[668,521]	[285,239]	0	hSpCas9	negative selection	4769137
137228834	137228856	9	+	27760321	HT1080	viability	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	-1.8104946787703915	[614,479]	[65,57]	-6	hSpCas9	negative selection	4769138
137228860	137228882	9	-	27760321	HT1080	viability	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	-0.7543971263308107	[712,556]	[85,219]	-3	hSpCas9	negative selection	4769139
137228727	137228749	9	-	27760321	HT29	viability after 7 days	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	0.09719382239007857	[735,574]	[957,868,884]	1	hSpCas9	negative selection	4852598
137228793	137228815	9	-	27760321	HT29	viability after 7 days	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	0.4158233945470564	[574,448]	[1111,907,653]	6	hSpCas9	negative selection	4852599
137228817	137228839	9	-	27760321	HT29	viability after 7 days	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	-0.002958088669624992	[668,521]	[792,985,523]	0	hSpCas9	negative selection	4852600
137228834	137228856	9	+	27760321	HT29	viability after 7 days	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	0.6584272909883067	[614,479]	[1061,815,1435]	8	hSpCas9	negative selection	4852601
137228860	137228882	9	-	27760321	HT29	viability after 7 days	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	0.8267691025561223	[712,556]	[1621,1161,1578]	9	hSpCas9	negative selection	4852602
137228727	137228749	9	-	27760321	HT29	viability after 25 days	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	0.1390330429320793	[735,574]	[677,909,902]	1	hSpCas9	negative selection	4936061
137228793	137228815	9	-	27760321	HT29	viability after 25 days	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	0.12031732782184457	[574,448]	[617,604,690]	1	hSpCas9	negative selection	4936062
137228817	137228839	9	-	27760321	HT29	viability after 25 days	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	0.2360860552668943	[668,521]	[672,1035,690]	2	hSpCas9	negative selection	4936063
137228834	137228856	9	+	27760321	HT29	viability after 25 days	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	0.3652997840504547	[614,479]	[681,613,1165]	4	hSpCas9	negative selection	4936064
137228860	137228882	9	-	27760321	HT29	viability after 25 days	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	0.4591360436760885	[712,556]	[999,953,1041]	5	hSpCas9	negative selection	4936065
137228727	137228749	9	-	27760321	HT29	viability after 22 days	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	0.16470213965003244	[735,574]	[816,809,922]	1	hSpCas9	negative selection	5019524
137228793	137228815	9	-	27760321	HT29	viability after 22 days	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	0.33322817627067225	[574,448]	[808,617,808]	3	hSpCas9	negative selection	5019525
137228817	137228839	9	-	27760321	HT29	viability after 22 days	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	0.19195566473568004	[668,521]	[791,986,577]	2	hSpCas9	negative selection	5019526
137228834	137228856	9	+	27760321	HT29	viability after 22 days	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	0.29463107083407825	[614,479]	[582,684,1068]	3	hSpCas9	negative selection	5019527
137228860	137228882	9	-	27760321	HT29	viability after 22 days	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	0.43997790798883596	[712,556]	[1135,947,898]	5	hSpCas9	negative selection	5019528
137228727	137228749	9	-	27760321	HT29	viability after 19 days	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	0.08099220127397933	[735,574]	[1011,664,726]	0	hSpCas9	negative selection	5102987
137228793	137228815	9	-	27760321	HT29	viability after 19 days	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	0.6208766269085534	[574,448]	[691,815,1160]	6	hSpCas9	negative selection	5102988
137228817	137228839	9	-	27760321	HT29	viability after 19 days	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	0.21988665609446678	[668,521]	[739,1069,571]	2	hSpCas9	negative selection	5102989
137228834	137228856	9	+	27760321	HT29	viability after 19 days	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	0.6238481407427936	[614,479]	[756,1195,920]	6	hSpCas9	negative selection	5102990
137228860	137228882	9	-	27760321	HT29	viability after 19 days	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	0.5461174946998597	[712,556]	[1106,841,1229]	5	hSpCas9	negative selection	5102991
137228727	137228749	9	-	27760321	HT29	viability after 16 days	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	-0.02013611035228091	[735,574]	[992,536,669]	0	hSpCas9	negative selection	5186450
137228793	137228815	9	-	27760321	HT29	viability after 16 days	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	0.393944546181241	[574,448]	[881,607,783]	4	hSpCas9	negative selection	5186451
137228817	137228839	9	-	27760321	HT29	viability after 16 days	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	0.030642797679480194	[668,521]	[774,543,734]	0	hSpCas9	negative selection	5186452
137228834	137228856	9	+	27760321	HT29	viability after 16 days	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	0.23824795084150463	[614,479]	[476,503,1168]	2	hSpCas9	negative selection	5186453
137228860	137228882	9	-	27760321	HT29	viability after 16 days	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	0.3986094598872145	[712,556]	[1370,807,674]	4	hSpCas9	negative selection	5186454
137228727	137228749	9	-	27760321	HT29	viability after 13 days	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	0.22439447721440453	[735,574]	[1082,866,724]	2	hSpCas9	negative selection	5269913
137228793	137228815	9	-	27760321	HT29	viability after 13 days	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	0.30359310440582055	[574,448]	[812,822,572]	4	hSpCas9	negative selection	5269914
137228817	137228839	9	-	27760321	HT29	viability after 13 days	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	0.33727530936441896	[668,521]	[824,983,812]	4	hSpCas9	negative selection	5269915
137228834	137228856	9	+	27760321	HT29	viability after 13 days	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	0.6783128115808457	[614,479]	[1141,876,1028]	8	hSpCas9	negative selection	5269916
137228860	137228882	9	-	27760321	HT29	viability after 13 days	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	0.4837206097736142	[712,556]	[741,1028,1302]	6	hSpCas9	negative selection	5269917
137228727	137228749	9	-	27760321	HT29	viability after 10 days	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	-0.16444159795624735	[735,574]	[708,823,661]	-2	hSpCas9	negative selection	5353376
137228793	137228815	9	-	27760321	HT29	viability after 10 days	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	0.21054716331061407	[574,448]	[822,620,770]	2	hSpCas9	negative selection	5353377
137228817	137228839	9	-	27760321	HT29	viability after 10 days	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	0.4955683260842354	[668,521]	[1289,1068,791]	6	hSpCas9	negative selection	5353378
137228834	137228856	9	+	27760321	HT29	viability after 10 days	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	0.506440567424894	[614,479]	[759,1044,1106]	7	hSpCas9	negative selection	5353379
137228860	137228882	9	-	27760321	HT29	viability after 10 days	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	0.707962048129622	[712,556]	[1353,1142,1381]	8	hSpCas9	negative selection	5353380
137228727	137228749	9	-	27760321	MOLM13	viability	GTCCACAGTAGAGGCGGCGGGG	RNF224	ENSG00000233198	0.10270916633644334	[956,735]	[844,222]	0	hSpCas9	negative selection	5436839
137228793	137228815	9	-	27760321	MOLM13	viability	AGGGGATCCAGCGCTGCTCGGG	RNF224	ENSG00000233198	0.5084397361231445	[774,574]	[779,329]	3	hSpCas9	negative selection	5436840
137228817	137228839	9	-	27760321	MOLM13	viability	GCGTGCTCTGACGGCACTGCGG	RNF224	ENSG00000233198	0.33989714096824986	[723,668]	[498,495]	2	hSpCas9	negative selection	5436841
137228834	137228856	9	+	27760321	MOLM13	viability	CACGCCCACGCCTCGCGGAGGG	RNF224	ENSG00000233198	-1.4630637849865273	[745,614]	[210,76]	-7	hSpCas9	negative selection	5436842
137228860	137228882	9	-	27760321	MOLM13	viability	GCCAGGTCCAGGTCTAGCATGG	RNF224	ENSG00000233198	1.7624358211867952	[866,712]	[1026,1911]	9	hSpCas9	negative selection	5436843
137227387	137227410	9	+	27661255	K562	viability	GGGCAGACTGCCAAGAAGGTGGG	RNF224	ENSG00000233198	-0.030289016491326204	[1093,1259]	[947,892]	-1	dCas9-KRAB	negative selection	5508010
137227538	137227561	9	+	27661255	K562	viability	GATCATACCTCCCGGAACCTGGG	RNF224	ENSG00000233198	0.1012690583597442	[1730,2164]	[1844,1506]	3	dCas9-KRAB	negative selection	5508011
137227724	137227747	9	+	27661255	K562	viability	GTCCAGCCGGCATCAAGGTGAGG	RNF224	ENSG00000233198	0.16194103967834805	[555,445]	[489,414]	5	dCas9-KRAB	negative selection	5508012
137227907	137227930	9	+	27661255	K562	viability	GGTAAGAGTGAGGGAGCGGAGGG	RNF224	ENSG00000233198	0.24814287505125027	[918,887]	[888,830]	8	dCas9-KRAB	negative selection	5508013
137228825	137228848	9	-	27260156	BXPC3	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.07079787707681734	[462]	[454,534,436,619]	1	hSpCas9	negative selection	5567740
137228829	137228852	9	+	27260156	BXPC3	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.04354506408663528	[1217]	[1108,1137,1357,1366]	-1	hSpCas9	negative selection	5567741
137228879	137228902	9	+	27260156	BXPC3	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.18414755766201107	[189]	[127,237,151,181]	-4	hSpCas9	negative selection	5567742
137228759	137228782	9	-	27260156	BXPC3	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.2579348684983669	[726]	[783,979,939,938]	5	hSpCas9	negative selection	5631994
137228785	137228808	9	+	27260156	BXPC3	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.21042621257125094	[254]	[152,227,296,254]	-5	hSpCas9	negative selection	5631995
137228852	137228875	9	+	27260156	BXPC3	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.005024434473442169	[546]	[462,638,562,624]	0	hSpCas9	negative selection	5631996
137228825	137228848	9	-	27260156	A673	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.019101339988910667	[462]	[647,501,499,556]	0	hSpCas9	negative selection	5688991
137228829	137228852	9	+	27260156	A673	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.04881051576482043	[1217]	[1602,1430,1422,1609]	1	hSpCas9	negative selection	5688992
137228879	137228902	9	+	27260156	A673	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	0.0938576561428659	[189]	[275,194,208,301]	2	hSpCas9	negative selection	5688993
137228759	137228782	9	-	27260156	A673	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.23138803417898135	[726]	[1086,989,979,1049]	5	hSpCas9	negative selection	5753245
137228785	137228808	9	+	27260156	A673	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.03323168397508425	[254]	[324,356,223,291]	-1	hSpCas9	negative selection	5753246
137228852	137228875	9	+	27260156	A673	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.10834956146975053	[546]	[778,652,632,779]	2	hSpCas9	negative selection	5753247
137228825	137228848	9	-	27260156	A375	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.07895847846477164	[462]	[548,547,615,356]	-1	hSpCas9	negative selection	5810242
137228829	137228852	9	+	27260156	A375	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.1015075869966191	[1217]	[1222,1789,1185,1180]	-1	hSpCas9	negative selection	5810243
137228879	137228902	9	+	27260156	A375	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.8053226234597539	[189]	[115,134,88,163]	-7	hSpCas9	negative selection	5810244
137228759	137228782	9	-	27260156	A375	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.17772633720016995	[726]	[1162,1054,935,726]	2	hSpCas9	negative selection	5874496
137228785	137228808	9	+	27260156	A375	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.5509159469922887	[254]	[259,249,213,106]	-6	hSpCas9	negative selection	5874497
137228852	137228875	9	+	27260156	A375	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.10641348380491286	[546]	[649,833,563,716]	1	hSpCas9	negative selection	5874498
137228825	137228848	9	-	27260156	COLO741	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.12087340170061925	[462]	[883,597,478]	2	hSpCas9	negative selection	5931493
137228829	137228852	9	+	27260156	COLO741	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.04629941655539094	[1217]	[1742,1622,1472]	1	hSpCas9	negative selection	5931494
137228879	137228902	9	+	27260156	COLO741	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.6150201283195178	[189]	[120,135,210]	-8	hSpCas9	negative selection	5931495
137228759	137228782	9	-	27260156	COLO741	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.1447122526459652	[726]	[941,1152,979]	3	hSpCas9	negative selection	5995747
137228785	137228808	9	+	27260156	COLO741	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	0.0708096930833112	[254]	[290,351,375]	1	hSpCas9	negative selection	5995748
137228852	137228875	9	+	27260156	COLO741	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.16423006974043666	[546]	[540,671,647]	-4	hSpCas9	negative selection	5995749
137228825	137228848	9	-	27260156	CAL120	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.19804858501587796	[462]	[665,584,730]	3	hSpCas9	negative selection	6052744
137228829	137228852	9	+	27260156	CAL120	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.15492017303886718	[1217]	[2112,1226,1783]	2	hSpCas9	negative selection	6052745
137228879	137228902	9	+	27260156	CAL120	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.3258814818922555	[189]	[111,237,203]	-5	hSpCas9	negative selection	6052746
137228759	137228782	9	-	27260156	CAL120	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.4338695239125745	[726]	[1542,892,1276]	6	hSpCas9	negative selection	6116998
137228785	137228808	9	+	27260156	CAL120	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.034976857316791454	[254]	[583,171,215]	0	hSpCas9	negative selection	6116999
137228852	137228875	9	+	27260156	CAL120	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.4366711453334756	[546]	[1316,695,811]	6	hSpCas9	negative selection	6117000
137228825	137228848	9	-	27260156	CADOES1	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.4159491710632283	[462]	[268,380,325,314]	-6	hSpCas9	negative selection	6173995
137228829	137228852	9	+	27260156	CADOES1	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.12291944706629376	[1217]	[1212,1207,881,850]	-2	hSpCas9	negative selection	6173996
137228879	137228902	9	+	27260156	CADOES1	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.39001740513633587	[189]	[187,147,50,152]	-6	hSpCas9	negative selection	6173997
137228759	137228782	9	-	27260156	CADOES1	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.38304914151412195	[726]	[804,709,896,1123]	6	hSpCas9	negative selection	6238249
137228785	137228808	9	+	27260156	CADOES1	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.009002173252403822	[254]	[254,272,173,240]	0	hSpCas9	negative selection	6238250
137228852	137228875	9	+	27260156	CADOES1	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.4146839522736442	[546]	[722,611,784,588]	7	hSpCas9	negative selection	6238251
137228825	137228848	9	-	27260156	EWS502	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.06801253050415614	[462]	[379,621,480,587]	1	hSpCas9	negative selection	6295246
137228829	137228852	9	+	27260156	EWS502	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.06630950287766413	[1217]	[1256,1340,1447,1365]	1	hSpCas9	negative selection	6295247
137228879	137228902	9	+	27260156	EWS502	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.4173461729499135	[189]	[154,105,112,234]	-6	hSpCas9	negative selection	6295248
137228759	137228782	9	-	27260156	EWS502	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.3418512649657599	[726]	[992,741,1109,1070]	6	hSpCas9	negative selection	6359500
137228785	137228808	9	+	27260156	EWS502	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	0.10972140396464591	[254]	[338,227,215,383]	2	hSpCas9	negative selection	6359501
137228852	137228875	9	+	27260156	EWS502	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.18364051233703513	[546]	[559,514,802,779]	3	hSpCas9	negative selection	6359502
137228825	137228848	9	-	27260156	EW8	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.09883134868908354	[462]	[481,251,335,554]	1	hSpCas9	negative selection	6416497
137228829	137228852	9	+	27260156	EW8	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.015996541263459063	[1217]	[1018,1042,1013,824]	0	hSpCas9	negative selection	6416498
137228879	137228902	9	+	27260156	EW8	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.04356502278639596	[189]	[169,185,99,151]	-1	hSpCas9	negative selection	6416499
137228759	137228782	9	-	27260156	EW8	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.14427512386215413	[726]	[673,639,573,729]	2	hSpCas9	negative selection	6480751
137228785	137228808	9	+	27260156	EW8	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.005171762424707627	[254]	[166,271,230,144]	0	hSpCas9	negative selection	6480752
137228852	137228875	9	+	27260156	EW8	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.3155090577690196	[546]	[535,610,549,506]	6	hSpCas9	negative selection	6480753
137228825	137228848	9	-	27260156	CORL105	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.024882921239594753	[462]	[522,492,679,529]	0	hSpCas9	negative selection	6537748
137228829	137228852	9	+	27260156	CORL105	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.2688980159764147	[1217]	[1664,1968,1857,1395]	5	hSpCas9	negative selection	6537749
137228879	137228902	9	+	27260156	CORL105	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.04795932424694116	[189]	[157,212,318,184]	-1	hSpCas9	negative selection	6537750
137228759	137228782	9	-	27260156	CORL105	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.5828641082054431	[726]	[1275,1227,1265,1327]	9	hSpCas9	negative selection	6602002
137228785	137228808	9	+	27260156	CORL105	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	0.055083297585289404	[254]	[370,292,315,263]	1	hSpCas9	negative selection	6602003
137228852	137228875	9	+	27260156	CORL105	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.10375857597748919	[546]	[810,612,649,677]	2	hSpCas9	negative selection	6602004
137228825	137228848	9	-	27260156	HS294T	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.07800387760622737	[462]	[141,137,194,213]	-1	hSpCas9	negative selection	6658999
137228829	137228852	9	+	27260156	HS294T	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.6226016294912684	[1217]	[604,693,814,810]	7	hSpCas9	negative selection	6659000
137228879	137228902	9	+	27260156	HS294T	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.3513024802792939	[189]	[61,36,40,96]	-5	hSpCas9	negative selection	6659001
137228759	137228782	9	-	27260156	HS294T	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.11293111224891861	[726]	[217,273,404,331]	1	hSpCas9	negative selection	6723253
137228785	137228808	9	+	27260156	HS294T	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	0.15162817932235262	[254]	[172,102,69,80]	2	hSpCas9	negative selection	6723254
137228852	137228875	9	+	27260156	HS294T	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.053429283455104754	[546]	[220,212,224,217]	0	hSpCas9	negative selection	6723255
137228825	137228848	9	-	27260156	HCC44	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.13358685981872326	[462]	[656,437,450,746]	2	hSpCas9	negative selection	6780250
137228829	137228852	9	+	27260156	HCC44	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.1780287471243105	[1217]	[1496,930,1689,900]	-3	hSpCas9	negative selection	6780251
137228879	137228902	9	+	27260156	HCC44	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	0.026128219439292	[189]	[137,200,320,225]	0	hSpCas9	negative selection	6780252
137228759	137228782	9	-	27260156	HCC44	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.17494948349206085	[726]	[1076,960,897,777]	2	hSpCas9	negative selection	6844504
137228785	137228808	9	+	27260156	HCC44	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.35751126622786067	[254]	[223,102,473,159]	-5	hSpCas9	negative selection	6844505
137228852	137228875	9	+	27260156	HCC44	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.0033636031420551937	[546]	[628,417,850,634]	0	hSpCas9	negative selection	6844506
137228825	137228848	9	-	27260156	G402	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.1642751233364383	[462]	[540,388,424,650]	-2	hSpCas9	negative selection	6901501
137228829	137228852	9	+	27260156	G402	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.10959709375517557	[1217]	[1800,1819,1218,780]	-1	hSpCas9	negative selection	6901502
137228879	137228902	9	+	27260156	G402	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	0.1591246605155472	[189]	[405,117,125,390]	2	hSpCas9	negative selection	6901503
137228759	137228782	9	-	27260156	G402	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.5484860197865136	[726]	[1798,1174,1149,1133]	6	hSpCas9	negative selection	6965755
137228785	137228808	9	+	27260156	G402	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-1.2125225153797907	[254]	[38,202,133,149]	-8	hSpCas9	negative selection	6965756
137228852	137228875	9	+	27260156	G402	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.2787653065619399	[546]	[871,520,771,1050]	3	hSpCas9	negative selection	6965757
137228825	137228848	9	-	27260156	L33	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.21180102310198168	[462]	[390,144,258,441]	-5	hSpCas9	negative selection	7022752
137228829	137228852	9	+	27260156	L33	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.11163374976901808	[1217]	[926,650,880,1355]	2	hSpCas9	negative selection	7022753
137228879	137228902	9	+	27260156	L33	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.09622199471200155	[189]	[141,63,146,179]	-2	hSpCas9	negative selection	7022754
137228759	137228782	9	-	27260156	L33	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.24059310232914066	[726]	[876,380,525,791]	5	hSpCas9	negative selection	7087006
137228785	137228808	9	+	27260156	L33	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.14706943311440634	[254]	[313,132,85,143]	-3	hSpCas9	negative selection	7087007
137228852	137228875	9	+	27260156	L33	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.07960029360267898	[546]	[498,206,344,517]	-2	hSpCas9	negative selection	7087008
137228825	137228848	9	-	27260156	K562	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.04820144847080854	[462]	[321,402,179,744]	0	hSpCas9	negative selection	7144003
137228829	137228852	9	+	27260156	K562	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.32163593611497965	[1217]	[904,1158,728,700]	-4	hSpCas9	negative selection	7144004
137228879	137228902	9	+	27260156	K562	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.20338091736715835	[189]	[78,339,82,93]	-3	hSpCas9	negative selection	7144005
137228759	137228782	9	-	27260156	K562	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.2752326635731829	[726]	[718,688,997,711]	3	hSpCas9	negative selection	7208257
137228785	137228808	9	+	27260156	K562	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.30718037381488694	[254]	[111,293,218,113]	-4	hSpCas9	negative selection	7208258
137228852	137228875	9	+	27260156	K562	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.20395769995610474	[546]	[434,238,490,500]	-3	hSpCas9	negative selection	7208259
137228825	137228848	9	-	27260156	HT29	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.3416088559691073	[462]	[483,589,297,419]	-6	hSpCas9	negative selection	7265254
137228829	137228852	9	+	27260156	HT29	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.11559558215518573	[1217]	[1606,1677,1265,996]	-2	hSpCas9	negative selection	7265255
137228879	137228902	9	+	27260156	HT29	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.12767639082524385	[189]	[233,181,302,133]	-3	hSpCas9	negative selection	7265256
137228759	137228782	9	-	27260156	HT29	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	-0.06036944406339673	[726]	[909,869,819,796]	-1	hSpCas9	negative selection	7329508
137228785	137228808	9	+	27260156	HT29	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.33009354085289766	[254]	[261,338,211,187]	-6	hSpCas9	negative selection	7329509
137228852	137228875	9	+	27260156	HT29	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.09104859709394819	[546]	[689,859,461,518]	-2	hSpCas9	negative selection	7329510
137228825	137228848	9	-	27260156	MHHES1	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.04710365244125822	[462]	[745,511,575,370]	0	hSpCas9	negative selection	7386505
137228829	137228852	9	+	27260156	MHHES1	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.021178529868099316	[1217]	[1657,1938,991,1100]	0	hSpCas9	negative selection	7386506
137228879	137228902	9	+	27260156	MHHES1	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.40209320334661913	[189]	[84,187,224,143]	-6	hSpCas9	negative selection	7386507
137228759	137228782	9	-	27260156	MHHES1	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.2589468763665933	[726]	[940,951,1223,812]	5	hSpCas9	negative selection	7450759
137228785	137228808	9	+	27260156	MHHES1	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.30772708036385665	[254]	[341,137,156,277]	-5	hSpCas9	negative selection	7450760
137228852	137228875	9	+	27260156	MHHES1	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.03559407169975873	[546]	[681,682,713,479]	0	hSpCas9	negative selection	7450761
137228825	137228848	9	-	27260156	MEWO	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.150575164517442	[462]	[552,548,353]	3	hSpCas9	negative selection	7507756
137228829	137228852	9	+	27260156	MEWO	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.19931796168658544	[1217]	[1476,1185,1294]	4	hSpCas9	negative selection	7507757
137228879	137228902	9	+	27260156	MEWO	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.7090343722840573	[189]	[142,73,115]	-8	hSpCas9	negative selection	7507758
137228759	137228782	9	-	27260156	MEWO	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.2209412056549367	[726]	[846,686,854]	5	hSpCas9	negative selection	7572010
137228785	137228808	9	+	27260156	MEWO	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	0.12962607752984967	[254]	[270,233,279]	3	hSpCas9	negative selection	7572011
137228852	137228875	9	+	27260156	MEWO	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.2563307816260262	[546]	[679,600,565]	5	hSpCas9	negative selection	7572012
137228825	137228848	9	-	27260156	LNCAPCLONEFGC	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.3509826113338649	[462]	[303,290,354,371]	-5	hSpCas9	negative selection	7629007
137228829	137228852	9	+	27260156	LNCAPCLONEFGC	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.06861367458828593	[1217]	[1066,962,1607,1070]	1	hSpCas9	negative selection	7629008
137228879	137228902	9	+	27260156	LNCAPCLONEFGC	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	0.028145573956882997	[189]	[114,160,208,223]	0	hSpCas9	negative selection	7629009
137228759	137228782	9	-	27260156	LNCAPCLONEFGC	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.2420648695184392	[726]	[787,717,867,757]	4	hSpCas9	negative selection	7693261
137228785	137228808	9	+	27260156	LNCAPCLONEFGC	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.3153893080676663	[254]	[215,116,162,246]	-5	hSpCas9	negative selection	7693262
137228852	137228875	9	+	27260156	LNCAPCLONEFGC	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.004367141321757195	[546]	[484,533,567,408]	0	hSpCas9	negative selection	7693263
137228825	137228848	9	-	27260156	PANC0327	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.24766194283817472	[462]	[398,375,310,299]	-4	hSpCas9	negative selection	7750258
137228829	137228852	9	+	27260156	PANC0327	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.20882029608583896	[1217]	[1439,1368,1278,913]	3	hSpCas9	negative selection	7750259
137228879	137228902	9	+	27260156	PANC0327	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	0.11387172627462272	[189]	[128,158,136,303]	1	hSpCas9	negative selection	7750260
137228759	137228782	9	-	27260156	PANC0327	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.3970034723086573	[726]	[939,1009,790,646]	6	hSpCas9	negative selection	7814512
137228785	137228808	9	+	27260156	PANC0327	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	0.025858207086694285	[254]	[219,126,309,277]	0	hSpCas9	negative selection	7814513
137228852	137228875	9	+	27260156	PANC0327	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.1987969902113245	[546]	[586,786,306,521]	3	hSpCas9	negative selection	7814514
137228825	137228848	9	-	27260156	NCIH2009	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.13582631430939007	[462]	[602,593,570]	-2	hSpCas9	negative selection	7871509
137228829	137228852	9	+	27260156	NCIH2009	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.337500787816156	[1217]	[2529,2104,1887]	4	hSpCas9	negative selection	7871510
137228879	137228902	9	+	27260156	NCIH2009	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	0.04289358985383318	[189]	[269,342,204]	0	hSpCas9	negative selection	7871511
137228759	137228782	9	-	27260156	NCIH2009	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.008313588524737847	[726]	[1192,1018,884]	0	hSpCas9	negative selection	7935763
137228785	137228808	9	+	27260156	NCIH2009	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	0.33178433044366296	[254]	[326,306,688]	4	hSpCas9	negative selection	7935764
137228852	137228875	9	+	27260156	NCIH2009	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.35068043747639793	[546]	[662,464,683]	-5	hSpCas9	negative selection	7935765
137228825	137228848	9	-	27260156	NCIH1373	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.17919491231514537	[462]	[785,274,330,276]	1	hSpCas9	negative selection	7992760
137228829	137228852	9	+	27260156	NCIH1373	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.1604614642625788	[1217]	[1930,1085,1509,443]	1	hSpCas9	negative selection	7992761
137228879	137228902	9	+	27260156	NCIH1373	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.44629045816761725	[189]	[433,104,86,10]	-4	hSpCas9	negative selection	7992762
137228759	137228782	9	-	27260156	NCIH1373	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.12138874387372667	[726]	[700,752,1042,271]	1	hSpCas9	negative selection	8057014
137228785	137228808	9	+	27260156	NCIH1373	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.012922458102756385	[254]	[241,319,385,42]	0	hSpCas9	negative selection	8057015
137228852	137228875	9	+	27260156	NCIH1373	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.07266955601564809	[546]	[337,785,425,191]	0	hSpCas9	negative selection	8057016
137228825	137228848	9	-	27260156	PATU8902	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.7193781567452897	[462]	[310,368,435,442]	-6	hSpCas9	negative selection	8114011
137228829	137228852	9	+	27260156	PATU8902	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.19379858433648245	[1217]	[1136,1743,1453,1613]	-2	hSpCas9	negative selection	8114012
137228879	137228902	9	+	27260156	PATU8902	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.2931438478525046	[189]	[159,395,114,218]	-3	hSpCas9	negative selection	8114013
137228759	137228782	9	-	27260156	PATU8902	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.21877132047902614	[726]	[886,976,1038,1929]	2	hSpCas9	negative selection	8178265
137228785	137228808	9	+	27260156	PATU8902	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-1.434155288698033	[254]	[96,210,96,128]	-8	hSpCas9	negative selection	8178266
137228852	137228875	9	+	27260156	PATU8902	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.036102274523270306	[546]	[648,530,657,1205]	0	hSpCas9	negative selection	8178267
137228825	137228848	9	-	27260156	PANC1	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.009706640324542156	[462]	[519,420,359,291]	0	hSpCas9	negative selection	8235262
137228829	137228852	9	+	27260156	PANC1	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.02938362662456373	[1217]	[771,1548,1316,771]	0	hSpCas9	negative selection	8235263
137228879	137228902	9	+	27260156	PANC1	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.07158700045916788	[189]	[148,96,204,155]	-1	hSpCas9	negative selection	8235264
137228759	137228782	9	-	27260156	PANC1	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.047245546098096725	[726]	[455,893,714,572]	0	hSpCas9	negative selection	8299516
137228785	137228808	9	+	27260156	PANC1	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.34069970275970285	[254]	[179,344,124,87]	-5	hSpCas9	negative selection	8299517
137228852	137228875	9	+	27260156	PANC1	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.22785504809371881	[546]	[387,563,391,303]	-4	hSpCas9	negative selection	8299518
137228825	137228848	9	-	27260156	PANC0813	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.07319286548125206	[462]	[648,636,519,492]	1	hSpCas9	negative selection	8356513
137228829	137228852	9	+	27260156	PANC0813	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.41568671005533475	[1217]	[2388,1905,1674,1714]	6	hSpCas9	negative selection	8356514
137228879	137228902	9	+	27260156	PANC0813	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	0.11080296229669262	[189]	[176,287,376,122]	1	hSpCas9	negative selection	8356515
137228759	137228782	9	-	27260156	PANC0813	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.22873865622363643	[726]	[970,1082,1114,838]	3	hSpCas9	negative selection	8420767
137228785	137228808	9	+	27260156	PANC0813	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.10093158837361826	[254]	[289,265,269,290]	-2	hSpCas9	negative selection	8420768
137228852	137228875	9	+	27260156	PANC0813	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.061691458771372915	[546]	[684,688,353,731]	-1	hSpCas9	negative selection	8420769
137228825	137228848	9	-	27260156	RDES	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.0896381737395135	[462]	[414,461,558,587]	-1	hSpCas9	negative selection	8477764
137228829	137228852	9	+	27260156	RDES	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.06602820263059228	[1217]	[1404,1278,1325,1898]	1	hSpCas9	negative selection	8477765
137228879	137228902	9	+	27260156	RDES	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	0.31572719991028264	[189]	[208,253,265,382]	5	hSpCas9	negative selection	8477766
137228759	137228782	9	-	27260156	RDES	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.3981119851464061	[726]	[887,1177,1183,1175]	6	hSpCas9	negative selection	8542018
137228785	137228808	9	+	27260156	RDES	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.23327961538725883	[254]	[229,267,292,193]	-4	hSpCas9	negative selection	8542019
137228852	137228875	9	+	27260156	RDES	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.2302255227764525	[546]	[585,706,728,979]	4	hSpCas9	negative selection	8542020
137228825	137228848	9	-	27260156	PC3	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.030180769479723205	[462]	[306,475,743,488]	0	hSpCas9	negative selection	8599015
137228829	137228852	9	+	27260156	PC3	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.10244343214523699	[1217]	[817,1488,1723,1423]	2	hSpCas9	negative selection	8599016
137228879	137228902	9	+	27260156	PC3	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.7375942732679701	[189]	[58,93,137,191]	-9	hSpCas9	negative selection	8599017
137228759	137228782	9	-	27260156	PC3	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.23679119979711527	[726]	[423,798,1602,1012]	5	hSpCas9	negative selection	8663269
137228785	137228808	9	+	27260156	PC3	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.2242941983853054	[254]	[254,153,275,154]	-5	hSpCas9	negative selection	8663270
137228852	137228875	9	+	27260156	PC3	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.38713474692645755	[546]	[409,722,983,916]	7	hSpCas9	negative selection	8663271
137228825	137228848	9	-	27260156	PATU8988T	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.02298843369954636	[462]	[425,378,450,563]	0	hSpCas9	negative selection	8720266
137228829	137228852	9	+	27260156	PATU8988T	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.2091693511085453	[1217]	[1216,1495,1580,1139]	3	hSpCas9	negative selection	8720267
137228879	137228902	9	+	27260156	PATU8988T	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.07534644001661528	[189]	[158,203,161,174]	-1	hSpCas9	negative selection	8720268
137228759	137228782	9	-	27260156	PATU8988T	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.510668569029759	[726]	[1125,785,1168,890]	8	hSpCas9	negative selection	8784520
137228785	137228808	9	+	27260156	PATU8988T	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.6967555574845495	[254]	[86,91,218,207]	-8	hSpCas9	negative selection	8784521
137228852	137228875	9	+	27260156	PATU8988T	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.24989150536854668	[546]	[644,580,675,604]	4	hSpCas9	negative selection	8784522
137228825	137228848	9	-	27260156	T47D	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.08168687046312414	[462]	[548,455,551,484]	-2	hSpCas9	negative selection	8841517
137228829	137228852	9	+	27260156	T47D	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.015245128604797431	[1217]	[1363,1402,1442,1404]	0	hSpCas9	negative selection	8841518
137228879	137228902	9	+	27260156	T47D	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.2043871085909621	[189]	[200,207,174,182]	-4	hSpCas9	negative selection	8841519
137228759	137228782	9	-	27260156	T47D	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.1946241259011402	[726]	[1159,772,875,1090]	4	hSpCas9	negative selection	8905771
137228785	137228808	9	+	27260156	T47D	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.1850899240635736	[254]	[329,221,260,234]	-4	hSpCas9	negative selection	8905772
137228852	137228875	9	+	27260156	T47D	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.016822734686391644	[546]	[671,566,612,736]	0	hSpCas9	negative selection	8905773
137228825	137228848	9	-	27260156	SU8686	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.1858283775374306	[462]	[524,390,551,655]	3	hSpCas9	negative selection	8962768
137228829	137228852	9	+	27260156	SU8686	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.13823727264699115	[1217]	[1362,1103,1381,1513]	2	hSpCas9	negative selection	8962769
137228879	137228902	9	+	27260156	SU8686	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.010092968363521804	[189]	[161,284,90,197]	0	hSpCas9	negative selection	8962770
137228759	137228782	9	-	27260156	SU8686	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.1981077238656077	[726]	[701,799,762,1095]	3	hSpCas9	negative selection	9027022
137228785	137228808	9	+	27260156	SU8686	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.17722814866626246	[254]	[186,148,251,337]	-3	hSpCas9	negative selection	9027023
137228852	137228875	9	+	27260156	SU8686	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.11918435574282743	[546]	[477,531,457,526]	-2	hSpCas9	negative selection	9027024
137228825	137228848	9	-	27260156	SKES1	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.12026056990569015	[462]	[498,648,509,376]	2	hSpCas9	negative selection	9084019
137228829	137228852	9	+	27260156	SKES1	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	-0.07424258449517507	[1217]	[1379,1204,1230,859]	-2	hSpCas9	negative selection	9084020
137228879	137228902	9	+	27260156	SKES1	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.6301860772127332	[189]	[131,98,165,92]	-8	hSpCas9	negative selection	9084021
137228759	137228782	9	-	27260156	SKES1	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.14951076016674114	[726]	[1020,778,682,759]	3	hSpCas9	negative selection	9148273
137228785	137228808	9	+	27260156	SKES1	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.09108988806571616	[254]	[308,300,200,167]	-2	hSpCas9	negative selection	9148274
137228852	137228875	9	+	27260156	SKES1	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.10269661084357865	[546]	[808,550,395,607]	2	hSpCas9	negative selection	9148275
137228825	137228848	9	-	27260156	TOV112D	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.24393856331436928	[462]	[469,507,619,579]	4	hSpCas9	negative selection	9205270
137228829	137228852	9	+	27260156	TOV112D	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.0902827268357631	[1217]	[1235,1676,1164,1204]	1	hSpCas9	negative selection	9205271
137228879	137228902	9	+	27260156	TOV112D	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.31099721124060475	[189]	[150,137,154,164]	-6	hSpCas9	negative selection	9205272
137228759	137228782	9	-	27260156	TOV112D	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.3872282257772761	[726]	[922,854,1151,853]	7	hSpCas9	negative selection	9269524
137228785	137228808	9	+	27260156	TOV112D	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.22007431762984953	[254]	[288,270,177,158]	-4	hSpCas9	negative selection	9269525
137228852	137228875	9	+	27260156	TOV112D	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.011548543011369566	[546]	[509,544,495,648]	0	hSpCas9	negative selection	9269526
137228825	137228848	9	-	27260156	TC71	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	0.21531073750091276	[462]	[463,619,554,674]	5	hSpCas9	negative selection	9326521
137228829	137228852	9	+	27260156	TC71	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.1731889327654479	[1217]	[1482,1443,1246,1737]	4	hSpCas9	negative selection	9326522
137228879	137228902	9	+	27260156	TC71	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	-0.2159223489683879	[189]	[141,164,195,199]	-5	hSpCas9	negative selection	9326523
137228759	137228782	9	-	27260156	TC71	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.2899189590241047	[726]	[827,1042,824,1132]	7	hSpCas9	negative selection	9390775
137228785	137228808	9	+	27260156	TC71	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.2882230139132419	[254]	[173,215,246,260]	-7	hSpCas9	negative selection	9390776
137228852	137228875	9	+	27260156	TC71	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	-0.04567805712119263	[546]	[573,505,575,618]	-1	hSpCas9	negative selection	9390777
137228825	137228848	9	-	27260156	TC32	viability	GAGGCGTGGGCGTGCTCTGACGG	RNF224	ENSG00000233198	-0.08149440102639462	[462]	[410,253,576,470]	-1	hSpCas9	negative selection	9447772
137228829	137228852	9	+	27260156	TC32	viability	CAGAGCACGCCCACGCCTCGCGG	RNF224	ENSG00000233198	0.06042734511117698	[1217]	[1340,623,1414,1583]	1	hSpCas9	negative selection	9447773
137228879	137228902	9	+	27260156	TC32	viability	GGCTGCTTTCCTGGCGGTCAAGG	RNF224	ENSG00000233198	0.09966155215461026	[189]	[174,206,171,190]	1	hSpCas9	negative selection	9447774
137228759	137228782	9	-	27260156	TC32	viability	CCAGCCGCCGCACACACGCCTGG	RNF224	ENSG00000233198	0.4019880944837908	[726]	[798,534,1224,1228]	7	hSpCas9	negative selection	9512026
137228785	137228808	9	+	27260156	TC32	viability	CACCGGCGCCCGAGCAGCGCTGG	RNF224	ENSG00000233198	-0.0927230098499715	[254]	[124,235,198,334]	-2	hSpCas9	negative selection	9512027
137228852	137228875	9	+	27260156	TC32	viability	AGGGGTGGCCATGCTAGACCTGG	RNF224	ENSG00000233198	0.33624239390107435	[546]	[642,591,747,607]	6	hSpCas9	negative selection	9512028
137228616	137228639	9	+	27869803	HPAFII	viability after 27 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.5605013690183394	[266]	[170,31,NaN]	-4	hSpCas9	negative selection	9605419
137228768	137228791	9	+	27869803	HPAFII	viability after 27 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.31385896067312324	[227]	[118,173,NaN]	2	hSpCas9	negative selection	9605420
137228876	137228899	9	-	27869803	HPAFII	viability after 27 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	-0.11716184769009697	[258]	[100,145,NaN]	-1	hSpCas9	negative selection	9605421
137228888	137228911	9	+	27869803	HPAFII	viability after 27 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	-0.5363385552539077	[160]	[53,61,NaN]	-4	hSpCas9	negative selection	9605422
137228958	137228981	9	+	27869803	HPAFII	viability after 27 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	1.8778091575628006	[125]	[411,102,NaN]	9	hSpCas9	negative selection	9605423
137228616	137228639	9	+	27869803	HPAFII	viability after 15 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.5382259189739422	[266]	[204,192,NaN]	-5	hSpCas9	negative selection	9687868
137228768	137228791	9	+	27869803	HPAFII	viability after 15 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	-0.18345262626882738	[227]	[171,242,NaN]	-2	hSpCas9	negative selection	9687869
137228876	137228899	9	-	27869803	HPAFII	viability after 15 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	0.1219623202091798	[258]	[580,129,NaN]	1	hSpCas9	negative selection	9687870
137228888	137228911	9	+	27869803	HPAFII	viability after 15 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	-0.4887133373349022	[160]	[81,148,NaN]	-5	hSpCas9	negative selection	9687871
137228958	137228981	9	+	27869803	HPAFII	viability after 15 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	1.535203716369967	[125]	[656,227,NaN]	9	hSpCas9	negative selection	9687872
137228616	137228639	9	+	27869803	ASPC1	viability after 36 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.1327043810981165	[723]	[250,141,283]	-1	hSpCas9	negative selection	9770317
137228768	137228791	9	+	27869803	ASPC1	viability after 36 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.584268284179157	[571]	[515,116,288]	6	hSpCas9	negative selection	9770318
137228876	137228899	9	-	27869803	ASPC1	viability after 36 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	1.2095192204545366	[637]	[511,549,483]	9	hSpCas9	negative selection	9770319
137228888	137228911	9	+	27869803	ASPC1	viability after 36 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	-0.3228415229391619	[312]	[58,20,158]	-3	hSpCas9	negative selection	9770320
137228958	137228981	9	+	27869803	ASPC1	viability after 36 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	-2.1455969078523633	[414]	[86,12,9]	-9	hSpCas9	negative selection	9770321
137228616	137228639	9	+	27869803	PATU8988S	viability after 35 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-1.5667894047519821	[822]	[62,160,NaN]	-8	hSpCas9	negative selection	9852766
137228768	137228791	9	+	27869803	PATU8988S	viability after 35 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.1426860595536087	[648]	[313,262,NaN]	1	hSpCas9	negative selection	9852767
137228876	137228899	9	-	27869803	PATU8988S	viability after 35 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	-0.4921299385178931	[685]	[166,225,NaN]	-5	hSpCas9	negative selection	9852768
137228888	137228911	9	+	27869803	PATU8988S	viability after 35 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	-1.0825950820292372	[325]	[59,63,NaN]	-7	hSpCas9	negative selection	9852769
137228958	137228981	9	+	27869803	PATU8988S	viability after 35 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	0.9138274613422236	[223]	[156,182,NaN]	8	hSpCas9	negative selection	9852770
137228616	137228639	9	+	27869803	PATU8988S	viability after 31 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-1.791631925854025	[822]	[41,161,NaN]	-9	hSpCas9	negative selection	9935215
137228768	137228791	9	+	27869803	PATU8988S	viability after 31 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.08741859473573815	[648]	[226,335,NaN]	1	hSpCas9	negative selection	9935216
137228876	137228899	9	-	27869803	PATU8988S	viability after 31 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	-0.4400607671088374	[685]	[132,288,NaN]	-5	hSpCas9	negative selection	9935217
137228888	137228911	9	+	27869803	PATU8988S	viability after 31 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	-0.11452549846354665	[325]	[72,179,NaN]	-1	hSpCas9	negative selection	9935218
137228958	137228981	9	+	27869803	PATU8988S	viability after 31 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	0.8517958498448829	[223]	[147,177,NaN]	8	hSpCas9	negative selection	9935219
137228616	137228639	9	+	27869803	HPAFII	viability after 35 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.17752585377087837	[266]	[214,11,NaN]	-1	hSpCas9	negative selection	10017664
137228768	137228791	9	+	27869803	HPAFII	viability after 35 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.1549340244596854	[227]	[88,172,NaN]	1	hSpCas9	negative selection	10017665
137228876	137228899	9	-	27869803	HPAFII	viability after 35 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	-0.5706946751935706	[258]	[60,118,NaN]	-3	hSpCas9	negative selection	10017666
137228888	137228911	9	+	27869803	HPAFII	viability after 35 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	-1.2443590585619126	[160]	[16,53,NaN]	-6	hSpCas9	negative selection	10017667
137228958	137228981	9	+	27869803	HPAFII	viability after 35 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	2.1365131127450105	[125]	[398,146,NaN]	9	hSpCas9	negative selection	10017668
137228616	137228639	9	+	27869803	HPAFII	viability after 31 days	TGGCAGGATGCTGCAGCCGGAGG	RNF224	ENSG00000233198	-0.6162999347049438	[266]	[147,42,NaN]	-4	hSpCas9	negative selection	10100113
137228768	137228791	9	+	27869803	HPAFII	viability after 31 days	TGTGCGGCGGCTGGACACACCGG	RNF224	ENSG00000233198	0.6227945285860058	[227]	[141,256,NaN]	4	hSpCas9	negative selection	10100114
137228876	137228899	9	-	27869803	HPAFII	viability after 31 days	TGACCGCCAGGAAAGCAGCCAGG	RNF224	ENSG00000233198	-0.15245472916171593	[258]	[136,123,NaN]	-1	hSpCas9	negative selection	10100115
137228888	137228911	9	+	27869803	HPAFII	viability after 31 days	CCTGGCGGTCAAGGCTGAGCGGG	RNF224	ENSG00000233198	-0.43793082214213674	[160]	[59,73,NaN]	-3	hSpCas9	negative selection	10100116
137228958	137228981	9	+	27869803	HPAFII	viability after 31 days	GCCATCACTCGGCAGCCAGCTGG	RNF224	ENSG00000233198	2.0357871442708957	[125]	[422,144,NaN]	9	hSpCas9	negative selection	10100117
137228732	137228755	9	-	28162770	P31FUJ	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	0.7329820802477084	[127]	[249]	8	hSpCas9	negative selection	10226546
137229060	137229083	9	-	28162770	P31FUJ	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	3.1457094188393513	[4]	[51]	9	hSpCas9	negative selection	10226547
137228755	137228778	9	+	28162770	P31FUJ	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	-0.5304827530550636	[117]	[95]	-4	hSpCas9	negative selection	10226548
137228665	137228688	9	-	28162770	P31FUJ	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.3339810387817461	[501]	[467]	-3	hSpCas9	negative selection	10226549
137228810	137228833	9	-	28162770	P31FUJ	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	0.9820761632647625	[164]	[382]	9	hSpCas9	negative selection	10226550
137228844	137228867	9	-	28162770	P31FUJ	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	-0.5356845436111944	[300]	[243]	-4	hSpCas9	negative selection	10226551
137228858	137228881	9	+	28162770	P31FUJ	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	0.3035111335990611	[381]	[553]	3	hSpCas9	negative selection	10226552
137228928	137228951	9	-	28162770	P31FUJ	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	-0.25499795052857493	[261]	[257]	-2	hSpCas9	negative selection	10226553
137228992	137229015	9	-	28162770	P31FUJ	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	0.26182355960232784	[334]	[471]	3	hSpCas9	negative selection	10226554
137229015	137229038	9	-	28162770	P31FUJ	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.256113608835743	[294]	[413]	2	hSpCas9	negative selection	10226555
137228732	137228755	9	-	28162770	TF1	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	NaN	[NaN]	[172]	1	hSpCas9	negative selection	10395912
137229060	137229083	9	-	28162770	TF1	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10395913
137228755	137228778	9	+	28162770	TF1	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10395914
137228665	137228688	9	-	28162770	TF1	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	NaN	[NaN]	[218]	1	hSpCas9	negative selection	10395915
137228810	137228833	9	-	28162770	TF1	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	NaN	[NaN]	[283]	1	hSpCas9	negative selection	10395916
137228844	137228867	9	-	28162770	TF1	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	NaN	[NaN]	[181]	1	hSpCas9	negative selection	10395917
137228858	137228881	9	+	28162770	TF1	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	NaN	[NaN]	[233]	1	hSpCas9	negative selection	10395918
137228928	137228951	9	-	28162770	TF1	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	NaN	[NaN]	[123]	1	hSpCas9	negative selection	10395919
137228992	137229015	9	-	28162770	TF1	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	NaN	[NaN]	[273]	1	hSpCas9	negative selection	10395920
137229015	137229038	9	-	28162770	TF1	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	NaN	[NaN]	[270]	1	hSpCas9	negative selection	10395921
137228732	137228755	9	-	28162770	SKM1	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	-0.4939475003378017	[46]	[58]	-4	hSpCas9	negative selection	10565278
137229060	137229083	9	-	28162770	SKM1	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	-2.406964198743162	[2]	[0]	-8	hSpCas9	negative selection	10565279
137228755	137228778	9	+	28162770	SKM1	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	0.7779111441651222	[31]	[96]	7	hSpCas9	negative selection	10565280
137228665	137228688	9	-	28162770	SKM1	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.42570076132474743	[154]	[203]	-3	hSpCas9	negative selection	10565281
137228810	137228833	9	-	28162770	SKM1	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	-0.5967093861797628	[70]	[82]	-5	hSpCas9	negative selection	10565282
137228844	137228867	9	-	28162770	SKM1	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	0.034088890579280884	[78]	[142]	0	hSpCas9	negative selection	10565283
137228858	137228881	9	+	28162770	SKM1	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	1.7629608026991506	[70]	[425]	9	hSpCas9	negative selection	10565284
137228928	137228951	9	-	28162770	SKM1	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	-0.33657487085176363	[34]	[48]	-3	hSpCas9	negative selection	10565285
137228992	137229015	9	-	28162770	SKM1	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	0.3017336704002393	[66]	[145]	3	hSpCas9	negative selection	10565286
137229015	137229038	9	-	28162770	SKM1	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.07108309806148268	[55]	[103]	0	hSpCas9	negative selection	10565287
137228732	137228755	9	-	28162770	SKM1	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	-0.4939475003378017	[46]	[58]	-4	hSpCas9	negative selection	10734644
137229060	137229083	9	-	28162770	SKM1	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	-2.406964198743162	[2]	[0]	-8	hSpCas9	negative selection	10734645
137228755	137228778	9	+	28162770	SKM1	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	0.7779111441651222	[31]	[96]	7	hSpCas9	negative selection	10734646
137228665	137228688	9	-	28162770	SKM1	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.42570076132474743	[154]	[203]	-3	hSpCas9	negative selection	10734647
137228810	137228833	9	-	28162770	SKM1	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	-0.5967093861797628	[70]	[82]	-5	hSpCas9	negative selection	10734648
137228844	137228867	9	-	28162770	SKM1	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	0.034088890579280884	[78]	[142]	0	hSpCas9	negative selection	10734649
137228858	137228881	9	+	28162770	SKM1	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	1.7629608026991506	[70]	[425]	9	hSpCas9	negative selection	10734650
137228928	137228951	9	-	28162770	SKM1	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	-0.33657487085176363	[34]	[48]	-3	hSpCas9	negative selection	10734651
137228992	137229015	9	-	28162770	SKM1	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	0.3017336704002393	[66]	[145]	3	hSpCas9	negative selection	10734652
137229015	137229038	9	-	28162770	SKM1	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.07108309806148268	[55]	[103]	0	hSpCas9	negative selection	10734653
137228732	137228755	9	-	28162770	PL21	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	0.531590483495189	[150]	[94]	4	hSpCas9	negative selection	10904010
137229060	137229083	9	-	28162770	PL21	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	-0.7998603855106801	[3]	[0]	-5	hSpCas9	negative selection	10904011
137228755	137228778	9	+	28162770	PL21	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	-0.2298482262554954	[96]	[35]	-2	hSpCas9	negative selection	10904012
137228665	137228688	9	-	28162770	PL21	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	0.4943952908921281	[578]	[354]	4	hSpCas9	negative selection	10904013
137228810	137228833	9	-	28162770	PL21	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	-0.520706314313609	[266]	[80]	-4	hSpCas9	negative selection	10904014
137228844	137228867	9	-	28162770	PL21	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	-0.4903770569899627	[325]	[100]	-3	hSpCas9	negative selection	10904015
137228858	137228881	9	+	28162770	PL21	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	0.45471244157491797	[227]	[135]	4	hSpCas9	negative selection	10904016
137228928	137228951	9	-	28162770	PL21	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	1.7788431247387941	[76]	[114]	9	hSpCas9	negative selection	10904017
137228992	137229015	9	-	28162770	PL21	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	0.1867190987269985	[215]	[106]	1	hSpCas9	negative selection	10904018
137229015	137229038	9	-	28162770	PL21	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.2965693771724129	[216]	[115]	2	hSpCas9	negative selection	10904019
137228732	137228755	9	-	28162770	P31FUJ	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	0.7329820802477084	[127]	[249]	8	hSpCas9	negative selection	11073376
137229060	137229083	9	-	28162770	P31FUJ	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	3.1457094188393513	[4]	[51]	9	hSpCas9	negative selection	11073377
137228755	137228778	9	+	28162770	P31FUJ	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	-0.5304827530550636	[117]	[95]	-4	hSpCas9	negative selection	11073378
137228665	137228688	9	-	28162770	P31FUJ	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.3339810387817461	[501]	[467]	-3	hSpCas9	negative selection	11073379
137228810	137228833	9	-	28162770	P31FUJ	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	0.9820761632647625	[164]	[382]	9	hSpCas9	negative selection	11073380
137228844	137228867	9	-	28162770	P31FUJ	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	-0.5356845436111944	[300]	[243]	-4	hSpCas9	negative selection	11073381
137228858	137228881	9	+	28162770	P31FUJ	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	0.3035111335990611	[381]	[553]	3	hSpCas9	negative selection	11073382
137228928	137228951	9	-	28162770	P31FUJ	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	-0.25499795052857493	[261]	[257]	-2	hSpCas9	negative selection	11073383
137228992	137229015	9	-	28162770	P31FUJ	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	0.26182355960232784	[334]	[471]	3	hSpCas9	negative selection	11073384
137229015	137229038	9	-	28162770	P31FUJ	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.256113608835743	[294]	[413]	2	hSpCas9	negative selection	11073385
137228732	137228755	9	-	28162770	OCIAML5	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	-0.0289443329480763	[77]	[137]	0	hSpCas9	negative selection	11242742
137229060	137229083	9	-	28162770	OCIAML5	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	-2.8520665708639967	[3]	[0]	-8	hSpCas9	negative selection	11242743
137228755	137228778	9	+	28162770	OCIAML5	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	-1.006394717255291	[68]	[61]	-6	hSpCas9	negative selection	11242744
137228665	137228688	9	-	28162770	OCIAML5	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.8064439537381998	[248]	[256]	-5	hSpCas9	negative selection	11242745
137228810	137228833	9	-	28162770	OCIAML5	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	0.14265848709532883	[136]	[272]	1	hSpCas9	negative selection	11242746
137228844	137228867	9	-	28162770	OCIAML5	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	0.3768746363013889	[156]	[367]	3	hSpCas9	negative selection	11242747
137228858	137228881	9	+	28162770	OCIAML5	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	0.849742577888593	[161]	[526]	7	hSpCas9	negative selection	11242748
137228928	137228951	9	-	28162770	OCIAML5	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	0.5025983104353653	[60]	[155]	4	hSpCas9	negative selection	11242749
137228992	137229015	9	-	28162770	OCIAML5	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	-0.45487707291807805	[182]	[240]	-3	hSpCas9	negative selection	11242750
137229015	137229038	9	-	28162770	OCIAML5	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.5879475939460596	[135]	[368]	5	hSpCas9	negative selection	11242751
137228732	137228755	9	-	28162770	EOL1	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	0.4770887945993132	[269]	[197]	4	hSpCas9	negative selection	11412108
137229060	137229083	9	-	28162770	EOL1	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	-0.2978446497659135	[6]	[2]	-2	hSpCas9	negative selection	11412109
137228755	137228778	9	+	28162770	EOL1	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	0.12214773145569524	[217]	[124]	1	hSpCas9	negative selection	11412110
137228665	137228688	9	-	28162770	EOL1	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-1.1157419494551823	[1052]	[255]	-6	hSpCas9	negative selection	11412111
137228810	137228833	9	-	28162770	EOL1	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	-0.1462050013513505	[396]	[188]	-1	hSpCas9	negative selection	11412112
137228844	137228867	9	-	28162770	EOL1	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	-0.6369557563266328	[548]	[185]	-4	hSpCas9	negative selection	11412113
137228858	137228881	9	+	28162770	EOL1	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	-0.04945701989652104	[329]	[167]	0	hSpCas9	negative selection	11412114
137228928	137228951	9	-	28162770	EOL1	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	-0.4740016049197404	[144]	[54]	-4	hSpCas9	negative selection	11412115
137228992	137229015	9	-	28162770	EOL1	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	0.12337672113630294	[290]	[166]	1	hSpCas9	negative selection	11412116
137229015	137229038	9	-	28162770	EOL1	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	-0.32143147008352924	[184]	[77]	-2	hSpCas9	negative selection	11412117
137228732	137228755	9	-	28162770	MOLM13	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	1.2883399612138662	[187]	[331]	8	hSpCas9	negative selection	11581474
137229060	137229083	9	-	28162770	MOLM13	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	1.708897481048374	[10]	[25]	9	hSpCas9	negative selection	11581475
137228755	137228778	9	+	28162770	MOLM13	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	2.031478231473168	[135]	[401]	9	hSpCas9	negative selection	11581476
137228665	137228688	9	-	28162770	MOLM13	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.6671768626860821	[827]	[376]	-4	hSpCas9	negative selection	11581477
137228810	137228833	9	-	28162770	MOLM13	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	0.33903431586815463	[315]	[288]	2	hSpCas9	negative selection	11581478
137228844	137228867	9	-	28162770	MOLM13	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	-0.5654306916554476	[437]	[213]	-3	hSpCas9	negative selection	11581479
137228858	137228881	9	+	28162770	MOLM13	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	0.8672219801175478	[253]	[334]	6	hSpCas9	negative selection	11581480
137228928	137228951	9	-	28162770	MOLM13	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	0.25429390844528976	[108]	[93]	1	hSpCas9	negative selection	11581481
137228992	137229015	9	-	28162770	MOLM13	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	0.25029794647195197	[249]	[214]	1	hSpCas9	negative selection	11581482
137229015	137229038	9	-	28162770	MOLM13	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.6656777627629344	[244]	[280]	5	hSpCas9	negative selection	11581483
137228732	137228755	9	-	28162770	HEL	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	-0.7369655941662062	[241]	[92]	-5	hSpCas9	negative selection	11750840
137229060	137229083	9	-	28162770	HEL	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	2.7302016732506966	[3]	[16]	9	hSpCas9	negative selection	11750841
137228755	137228778	9	+	28162770	HEL	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	0.05101896510389192	[106]	[70]	0	hSpCas9	negative selection	11750842
137228665	137228688	9	-	28162770	HEL	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.6715255261888358	[750]	[301]	-4	hSpCas9	negative selection	11750843
137228810	137228833	9	-	28162770	HEL	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	-0.45977607862557734	[276]	[128]	-3	hSpCas9	negative selection	11750844
137228844	137228867	9	-	28162770	HEL	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	0.38966881238490614	[403]	[338]	3	hSpCas9	negative selection	11750845
137228858	137228881	9	+	28162770	HEL	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	-0.5406066852042771	[242]	[106]	-4	hSpCas9	negative selection	11750846
137228928	137228951	9	-	28162770	HEL	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	0.06497183268340456	[99]	[66]	0	hSpCas9	negative selection	11750847
137228992	137229015	9	-	28162770	HEL	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	-0.666307971590273	[222]	[89]	-4	hSpCas9	negative selection	11750848
137229015	137229038	9	-	28162770	HEL	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.8935469355008914	[157]	[187]	7	hSpCas9	negative selection	11750849
137228732	137228755	9	-	28162770	MV411	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	-0.36098392276236985	[185]	[121]	-3	hSpCas9	negative selection	11920206
137229060	137229083	9	-	28162770	MV411	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	0.24743755078277552	[3]	[3]	2	hSpCas9	negative selection	11920207
137228755	137228778	9	+	28162770	MV411	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	-0.052122731076132744	[111]	[90]	0	hSpCas9	negative selection	11920208
137228665	137228688	9	-	28162770	MV411	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-1.807667048657679	[506]	[121]	-8	hSpCas9	negative selection	11920209
137228810	137228833	9	-	28162770	MV411	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	0.8635225689997121	[213]	[327]	7	hSpCas9	negative selection	11920210
137228844	137228867	9	-	28162770	MV411	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	-0.21929318267756148	[321]	[232]	-2	hSpCas9	negative selection	11920211
137228858	137228881	9	+	28162770	MV411	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	0.7587430097786226	[220]	[314]	7	hSpCas9	negative selection	11920212
137228928	137228951	9	-	28162770	MV411	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	0.5892260680309807	[100]	[127]	5	hSpCas9	negative selection	11920213
137228992	137229015	9	-	28162770	MV411	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	0.6243704450361168	[210]	[273]	5	hSpCas9	negative selection	11920214
137229015	137229038	9	-	28162770	MV411	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.7059766886982056	[146]	[201]	6	hSpCas9	negative selection	11920215
137228732	137228755	9	-	28162770	MONOMAC1	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	0.6749555405643748	[105]	[193]	6	hSpCas9	negative selection	12089572
137229060	137229083	9	-	28162770	MONOMAC1	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	-1.78199934778071	[2]	[0]	-8	hSpCas9	negative selection	12089573
137228755	137228778	9	+	28162770	MONOMAC1	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	1.410433053071172	[105]	[322]	9	hSpCas9	negative selection	12089574
137228665	137228688	9	-	28162770	MONOMAC1	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.2377831894028628	[394]	[383]	-2	hSpCas9	negative selection	12089575
137228810	137228833	9	-	28162770	MONOMAC1	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	0.12489124782780868	[123]	[154]	1	hSpCas9	negative selection	12089576
137228844	137228867	9	-	28162770	MONOMAC1	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	0.30079306193562816	[181]	[256]	3	hSpCas9	negative selection	12089577
137228858	137228881	9	+	28162770	MONOMAC1	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	0.13999814021801693	[151]	[191]	1	hSpCas9	negative selection	12089578
137228928	137228951	9	-	28162770	MONOMAC1	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	-0.0757305508374202	[56]	[61]	0	hSpCas9	negative selection	12089579
137228992	137229015	9	-	28162770	MONOMAC1	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	0.054024917108164025	[120]	[143]	0	hSpCas9	negative selection	12089580
137229015	137229038	9	-	28162770	MONOMAC1	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.2279847407919123	[107]	[144]	2	hSpCas9	negative selection	12089581
137228732	137228755	9	-	28162770	OCIAML2	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	0.25519521131884443	[25]	[171]	2	hSpCas9	negative selection	12258938
137229060	137229083	9	-	28162770	OCIAML2	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	-4.4706298252421615	[3]	[0]	-9	hSpCas9	negative selection	12258939
137228755	137228778	9	+	28162770	OCIAML2	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	-0.29518781883228307	[28]	[130]	-2	hSpCas9	negative selection	12258940
137228665	137228688	9	-	28162770	OCIAML2	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.6687569682009729	[112]	[393]	-5	hSpCas9	negative selection	12258941
137228810	137228833	9	-	28162770	OCIAML2	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	-0.4902586319910938	[36]	[145]	-4	hSpCas9	negative selection	12258942
137228844	137228867	9	-	28162770	OCIAML2	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	-0.946208866456056	[72]	[209]	-6	hSpCas9	negative selection	12258943
137228858	137228881	9	+	28162770	OCIAML2	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	0.8723598851730306	[33]	[344]	8	hSpCas9	negative selection	12258944
137228928	137228951	9	-	28162770	OCIAML2	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	0.04033209403521831	[9]	[56]	0	hSpCas9	negative selection	12258945
137228992	137229015	9	-	28162770	OCIAML2	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	0.03974335905831128	[42]	[244]	0	hSpCas9	negative selection	12258946
137229015	137229038	9	-	28162770	OCIAML2	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	0.21009165828442575	[33]	[217]	2	hSpCas9	negative selection	12258947
137228732	137228755	9	-	28162770	OCIAML3	viability	AGGTGTGTCCACAGTAGAGGCGG	RNF224	ENSG00000233198	-0.9159357352115254	[39]	[63]	-6	hSpCas9	negative selection	12428304
137229060	137229083	9	-	28162770	OCIAML3	viability	ACCTCGGGGCTGCCTAGGGGTGG	RNF224	ENSG00000233198	-4.178970141045319	[5]	[0]	-9	hSpCas9	negative selection	12428305
137228755	137228778	9	+	28162770	OCIAML3	viability	TCTGCCAGGCGTGTGTGCGGCGG	RNF224	ENSG00000233198	0.9816770468089823	[25]	[154]	8	hSpCas9	negative selection	12428306
137228665	137228688	9	-	28162770	OCIAML3	viability	GCAGTCTGTCCTCTCCTCCGGGG	RNF224	ENSG00000233198	-0.45467095871527385	[142]	[314]	-4	hSpCas9	negative selection	12428307
137228810	137228833	9	-	28162770	OCIAML3	viability	TCTGACGGCACTGCGGACAGGGG	RNF224	ENSG00000233198	-0.4045298414604503	[56]	[129]	-3	hSpCas9	negative selection	12428308
137228844	137228867	9	-	28162770	OCIAML3	viability	AGCATGGCCACCCCTCCGCGAGG	RNF224	ENSG00000233198	-0.719538522408022	[77]	[142]	-5	hSpCas9	negative selection	12428309
137228858	137228881	9	+	28162770	OCIAML3	viability	GGCCATGCTAGACCTGGACCTGG	RNF224	ENSG00000233198	0.3455277184119425	[66]	[256]	3	hSpCas9	negative selection	12428310
137228928	137228951	9	-	28162770	OCIAML3	viability	TTGAGGGAGGTGAGGGGCAGGGG	RNF224	ENSG00000233198	0.32353019948386375	[26]	[101]	3	hSpCas9	negative selection	12428311
137228992	137229015	9	-	28162770	OCIAML3	viability	GAAGTGGGGCTGGGGTCCCAGGG	RNF224	ENSG00000233198	-0.1406420223862198	[64]	[177]	-1	hSpCas9	negative selection	12428312
137229015	137229038	9	-	28162770	OCIAML3	viability	CAGCAGCAGTATCTGGGCTGGGG	RNF224	ENSG00000233198	1.0350100404749285	[42]	[265]	8	hSpCas9	negative selection	12428313