Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 54894
• Symbol: RNF43
• Description: ring finger protein 43

DataSource: http://genomecrispr.dkfz.de/#!/results/RNF43

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
58415567	58415590	17	-	26472758	Jiyoye	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-1.4583744187217458	[214]	[58]	-7	hSpCas9	negative selection	138556
58358155	58358178	17	-	26472758	Jiyoye	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	-1.2132359552195726	[205]	[66]	-7	hSpCas9	negative selection	138557
58415469	58415492	17	-	26472758	Jiyoye	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	1.5107980125800307	[93]	[201]	8	hSpCas9	negative selection	138558
58362612	58362635	17	-	26472758	Jiyoye	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	-0.03743523315631758	[229]	[168]	0	hSpCas9	negative selection	138559
58360879	58360902	17	+	26472758	Jiyoye	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	0.3854803104065543	[267]	[263]	3	hSpCas9	negative selection	138560
58360804	58360827	17	+	26472758	Jiyoye	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	-0.4001795405517307	[160]	[91]	-3	hSpCas9	negative selection	138561
58360197	58360220	17	+	26472758	Jiyoye	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	-0.8603049293591125	[129]	[53]	-6	hSpCas9	negative selection	138562
58358737	58358760	17	+	26472758	Jiyoye	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-0.2708965236067642	[15]	[9]	-2	hSpCas9	negative selection	138563
58358701	58358724	17	+	26472758	Jiyoye	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-0.045336823191633346	[25]	[18]	0	hSpCas9	negative selection	138564
58358677	58358700	17	-	26472758	Jiyoye	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	-0.7225156951337635	[220]	[100]	-5	hSpCas9	negative selection	138565
58415567	58415590	17	-	26472758	KBM7	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-0.36433980758954926	[557,385]	[178,161]	-3	hSpCas9	negative selection	329674
58358155	58358178	17	-	26472758	KBM7	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	0.9206997624394779	[486,411]	[367,425]	8	hSpCas9	negative selection	329675
58415469	58415492	17	-	26472758	KBM7	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	0.2379336003406745	[466,396]	[243,233]	2	hSpCas9	negative selection	329676
58362612	58362635	17	-	26472758	KBM7	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	0.18979977159962125	[822,693]	[485,332]	2	hSpCas9	negative selection	329677
58360879	58360902	17	+	26472758	KBM7	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	-0.17740746656427753	[1337,850]	[485,411]	-2	hSpCas9	negative selection	329678
58360804	58360827	17	+	26472758	KBM7	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	0.5895045941593935	[665,514]	[605,242]	6	hSpCas9	negative selection	329679
58360197	58360220	17	+	26472758	KBM7	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.2432529723880562	[450,399]	[292,185]	2	hSpCas9	negative selection	329680
58358737	58358760	17	+	26472758	KBM7	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-0.2431778009785428	[50,46]	[0,35]	-2	hSpCas9	negative selection	329681
58358701	58358724	17	+	26472758	KBM7	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-0.9599875293622528	[114,199]	[42,35]	-6	hSpCas9	negative selection	329682
58358677	58358700	17	-	26472758	KBM7	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	0.6053576528489152	[576,288]	[428,185]	6	hSpCas9	negative selection	329683
58415567	58415590	17	-	26472758	Raji	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	0.2075476972990315	[152]	[40]	2	hSpCas9	negative selection	520792
58358155	58358178	17	-	26472758	Raji	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	0.9629936260384248	[209]	[94]	8	hSpCas9	negative selection	520793
58415469	58415492	17	-	26472758	Raji	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.48389273927975884	[228]	[37]	-4	hSpCas9	negative selection	520794
58362612	58362635	17	-	26472758	Raji	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	0.21780752506724999	[351]	[94]	2	hSpCas9	negative selection	520795
58360879	58360902	17	+	26472758	Raji	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	0.11716455616618493	[587]	[147]	1	hSpCas9	negative selection	520796
58360804	58360827	17	+	26472758	Raji	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	-0.07095370588491297	[257]	[56]	0	hSpCas9	negative selection	520797
58360197	58360220	17	+	26472758	Raji	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.929046294115087	[85]	[37]	8	hSpCas9	negative selection	520798
58358737	58358760	17	+	26472758	Raji	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	1.1073835353735988	[13]	[6]	8	hSpCas9	negative selection	520799
58358701	58358724	17	+	26472758	Raji	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-3.214544559513763	[39]	[0]	-9	hSpCas9	negative selection	520800
58358677	58358700	17	-	26472758	Raji	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	-0.17501619532712553	[359]	[73]	-1	hSpCas9	negative selection	520801
58415567	58415590	17	-	26472758	K562	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-0.6341614719186944	[409]	[222]	-4	hSpCas9	negative selection	711910
58358155	58358178	17	-	26472758	K562	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	0.04293177297224415	[490]	[426]	0	hSpCas9	negative selection	711911
58415469	58415492	17	-	26472758	K562	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	0.3387461102145999	[369]	[394]	2	hSpCas9	negative selection	711912
58362612	58362635	17	-	26472758	K562	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	-0.1696316384634582	[973]	[730]	-1	hSpCas9	negative selection	711913
58360879	58360902	17	+	26472758	K562	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	-1.3234026402333154	[752]	[253]	-6	hSpCas9	negative selection	711914
58360804	58360827	17	+	26472758	K562	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	0.6376518566269422	[449]	[590]	5	hSpCas9	negative selection	711915
58360197	58360220	17	+	26472758	K562	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.16483046292858408	[353]	[334]	1	hSpCas9	negative selection	711916
58358737	58358760	17	+	26472758	K562	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	1.3105079181242192	[31]	[66]	9	hSpCas9	negative selection	711917
58358701	58358724	17	+	26472758	K562	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-3.5629361943911575	[153]	[10]	-8	hSpCas9	negative selection	711918
58358677	58358700	17	-	26472758	K562	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	0.6964694176316464	[480]	[657]	6	hSpCas9	negative selection	711919
58360891	58360914	17	-	26627737	DLD1	viability	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.26422234324348765	[419]	[119,209,146]	2	hSpCas9	negative selection	799044
58362586	58362609	17	+	26627737	DLD1	viability	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.7264114223758278	[680]	[380,430,261]	7	hSpCas9	negative selection	799045
58363263	58363286	17	+	26627737	DLD1	viability	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.4490979421454766	[647]	[200,383,252]	4	hSpCas9	negative selection	799046
58363525	58363548	17	-	26627737	DLD1	viability	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	0.36314483873896275	[358]	[155,140,136]	4	hSpCas9	negative selection	799047
58370997	58371020	17	+	26627737	DLD1	viability	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.29924344433207706	[1719]	[563,697,715]	3	hSpCas9	negative selection	799048
58415469	58415492	17	-	26627737	DLD1	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	0.5058852143911614	[353]	[138,133,191]	5	hSpCas9	negative selection	799049
58360891	58360914	17	-	26627737	GBM cells	viability after 5 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.24904400650141567	[276]	[130,118]	-4	hSpCas9	negative selection	881359
58362586	58362609	17	+	26627737	GBM cells	viability after 5 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.3382320093675477	[544]	[367,370]	5	hSpCas9	negative selection	881360
58363263	58363286	17	+	26627737	GBM cells	viability after 5 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.1884204920806707	[368]	[230,219]	3	hSpCas9	negative selection	881361
58363525	58363548	17	-	26627737	GBM cells	viability after 5 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	0.3495752838952506	[179]	[101,143]	5	hSpCas9	negative selection	881362
58370997	58371020	17	+	26627737	GBM cells	viability after 5 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.09663369762867435	[673]	[426,345]	1	hSpCas9	negative selection	881363
58415469	58415492	17	-	26627737	GBM cells	viability after 5 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	0.024444756969544512	[120]	[64,66]	0	hSpCas9	negative selection	881364
58360891	58360914	17	-	26627737	GBM cells	viability after 13 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.09479867434769225	[276]	[164,120]	-1	hSpCas9	negative selection	963674
58362586	58362609	17	+	26627737	GBM cells	viability after 13 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.010660773430554604	[544]	[373,235]	0	hSpCas9	negative selection	963675
58363263	58363286	17	+	26627737	GBM cells	viability after 13 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.3313586964364934	[368]	[193,298]	4	hSpCas9	negative selection	963676
58363525	58363548	17	-	26627737	GBM cells	viability after 13 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	-0.10475577673348635	[179]	[81,97]	-1	hSpCas9	negative selection	963677
58370997	58371020	17	+	26627737	GBM cells	viability after 13 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	-0.2704176993043592	[673]	[343,269]	-3	hSpCas9	negative selection	963678
58415469	58415492	17	-	26627737	GBM cells	viability after 13 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.44144777587945927	[120]	[49,46]	-5	hSpCas9	negative selection	963679
58360891	58360914	17	-	26627737	GBM cells	viability after 21 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.09441233593033464	[276]	[141,139]	-1	hSpCas9	negative selection	1045989
58362586	58362609	17	+	26627737	GBM cells	viability after 21 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.0826470270594375	[544]	[335,292]	0	hSpCas9	negative selection	1045990
58363263	58363286	17	+	26627737	GBM cells	viability after 21 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.6526257135915474	[368]	[299,328]	6	hSpCas9	negative selection	1045991
58363525	58363548	17	-	26627737	GBM cells	viability after 21 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	0.4006012214768858	[179]	[126,130]	4	hSpCas9	negative selection	1045992
58370997	58371020	17	+	26627737	GBM cells	viability after 21 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	-0.030050403427706707	[673]	[343,371]	0	hSpCas9	negative selection	1045993
58415469	58415492	17	-	26627737	GBM cells	viability after 21 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.36620459568744046	[120]	[50,50]	-3	hSpCas9	negative selection	1045994
58360891	58360914	17	-	26627737	RPE1	viability after 9 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.1382124428321492	[844]	[267,320]	1	hSpCas9	negative selection	1128304
58362586	58362609	17	+	26627737	RPE1	viability after 9 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.2206162495328715	[1519]	[581,518]	1	hSpCas9	negative selection	1128305
58363263	58363286	17	+	26627737	RPE1	viability after 9 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	-0.4569207386303029	[1938]	[474,399]	-3	hSpCas9	negative selection	1128306
58363525	58363548	17	-	26627737	RPE1	viability after 9 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	0.4302894238216125	[522]	[255,174]	3	hSpCas9	negative selection	1128307
58370997	58371020	17	+	26627737	RPE1	viability after 9 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	1.4812413871798706	[1399]	[1279,1150]	8	hSpCas9	negative selection	1128308
58415469	58415492	17	-	26627737	RPE1	viability after 9 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-2.023960355155346	[766]	[48,71]	-8	hSpCas9	negative selection	1128309
58360891	58360914	17	-	26627737	RPE1	viability after 12 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.7416600156406096	[844]	[144,125]	-5	hSpCas9	negative selection	1210619
58362586	58362609	17	+	26627737	RPE1	viability after 12 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.08314565841680632	[1519]	[384,482]	0	hSpCas9	negative selection	1210620
58363263	58363286	17	+	26627737	RPE1	viability after 12 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	-0.1475043321875924	[1938]	[412,530]	-1	hSpCas9	negative selection	1210621
58363525	58363548	17	-	26627737	RPE1	viability after 12 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	0.42550410461542004	[522]	[229,144]	3	hSpCas9	negative selection	1210622
58370997	58371020	17	+	26627737	RPE1	viability after 12 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	1.5556632288149776	[1399]	[1316,881]	8	hSpCas9	negative selection	1210623
58415469	58415492	17	-	26627737	RPE1	viability after 12 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-2.0960101144871963	[766]	[3,94]	-8	hSpCas9	negative selection	1210624
58360891	58360914	17	-	26627737	RPE1	viability after 15 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.4833779429527003	[844]	[143,196]	-3	hSpCas9	negative selection	1292934
58362586	58362609	17	+	26627737	RPE1	viability after 15 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.3000287295848524	[1519]	[620,440]	2	hSpCas9	negative selection	1292935
58363263	58363286	17	+	26627737	RPE1	viability after 15 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.3096634702082055	[1938]	[942,425]	2	hSpCas9	negative selection	1292936
58363525	58363548	17	-	26627737	RPE1	viability after 15 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	0.5321826197166862	[522]	[216,210]	3	hSpCas9	negative selection	1292937
58370997	58371020	17	+	26627737	RPE1	viability after 15 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	1.696705392345561	[1399]	[1774,809]	8	hSpCas9	negative selection	1292938
58415469	58415492	17	-	26627737	RPE1	viability after 15 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-2.7829146050685094	[766]	[1,59]	-9	hSpCas9	negative selection	1292939
58360891	58360914	17	-	26627737	RPE1	viability after 18 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.9266475799435501	[844]	[118,120]	-5	hSpCas9	negative selection	1375249
58362586	58362609	17	+	26627737	RPE1	viability after 18 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.5211468803229461	[1519]	[622,551]	3	hSpCas9	negative selection	1375250
58363263	58363286	17	+	26627737	RPE1	viability after 18 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.1340021260644424	[1938]	[725,411]	0	hSpCas9	negative selection	1375251
58363525	58363548	17	-	26627737	RPE1	viability after 18 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	0.8027658343964023	[522]	[266,223]	5	hSpCas9	negative selection	1375252
58370997	58371020	17	+	26627737	RPE1	viability after 18 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	1.8092994731305612	[1399]	[1473,1163]	8	hSpCas9	negative selection	1375253
58415469	58415492	17	-	26627737	RPE1	viability after 18 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-2.8335485601320474	[766]	[0,58]	-9	hSpCas9	negative selection	1375254
58360891	58360914	17	-	26627737	HeLa	viability after 8 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.17448884310113916	[390]	[91,161,182]	-2	hSpCas9	negative selection	1457564
58362586	58362609	17	+	26627737	HeLa	viability after 8 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	-0.5070172978395122	[1208]	[354,363,386]	-5	hSpCas9	negative selection	1457565
58363263	58363286	17	+	26627737	HeLa	viability after 8 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.023279832977807113	[531]	[170,364,160]	0	hSpCas9	negative selection	1457566
58363525	58363548	17	-	26627737	HeLa	viability after 8 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	1.1771378215581385	[175]	[169,192,156]	8	hSpCas9	negative selection	1457567
58370997	58371020	17	+	26627737	HeLa	viability after 8 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	-0.08658186718055871	[1231]	[693,383,479]	-1	hSpCas9	negative selection	1457568
58415469	58415492	17	-	26627737	HeLa	viability after 8 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-1.8614918007947472	[475]	[53,83,33]	-9	hSpCas9	negative selection	1457569
58360891	58360914	17	-	26627737	HeLa	viability after 12 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.4448431768745499	[390]	[316,178,170]	4	hSpCas9	negative selection	1539879
58362586	58362609	17	+	26627737	HeLa	viability after 12 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	-0.4810620483667922	[1208]	[544,228,318]	-4	hSpCas9	negative selection	1539880
58363263	58363286	17	+	26627737	HeLa	viability after 12 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.7211952990025756	[531]	[333,253,509]	6	hSpCas9	negative selection	1539881
58363525	58363548	17	-	26627737	HeLa	viability after 12 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	1.5023542052181924	[175]	[104,264,238]	8	hSpCas9	negative selection	1539882
58370997	58371020	17	+	26627737	HeLa	viability after 12 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.441763581393142	[1231]	[980,644,461]	4	hSpCas9	negative selection	1539883
58415469	58415492	17	-	26627737	HeLa	viability after 12 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-1.2481673638086839	[475]	[130,52,68]	-8	hSpCas9	negative selection	1539884
58360891	58360914	17	-	26627737	HeLa	viability after 15 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.19216277337992024	[390]	[53,156,348]	1	hSpCas9	negative selection	1622194
58362586	58362609	17	+	26627737	HeLa	viability after 15 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	-0.3323663564524899	[1208]	[431,230,518]	-3	hSpCas9	negative selection	1622195
58363263	58363286	17	+	26627737	HeLa	viability after 15 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.4523622860061649	[531]	[212,236,451]	4	hSpCas9	negative selection	1622196
58363525	58363548	17	-	26627737	HeLa	viability after 15 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	1.8294211389025143	[175]	[273,218,271]	9	hSpCas9	negative selection	1622197
58370997	58371020	17	+	26627737	HeLa	viability after 15 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.3657266210281702	[1231]	[763,795,354]	3	hSpCas9	negative selection	1622198
58415469	58415492	17	-	26627737	HeLa	viability after 15 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-1.3871994680940065	[475]	[41,17,169]	-8	hSpCas9	negative selection	1622199
58360891	58360914	17	-	26627737	HeLa	viability after 18 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.19529055951362143	[390]	[40,124,348]	1	hSpCas9	negative selection	1704509
58362586	58362609	17	+	26627737	HeLa	viability after 18 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	-0.3211723586526871	[1208]	[303,180,518]	-3	hSpCas9	negative selection	1704510
58363263	58363286	17	+	26627737	HeLa	viability after 18 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.4827992285564934	[531]	[148,203,451]	4	hSpCas9	negative selection	1704511
58363525	58363548	17	-	26627737	HeLa	viability after 18 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	1.8794704336882093	[175]	[195,187,271]	9	hSpCas9	negative selection	1704512
58370997	58371020	17	+	26627737	HeLa	viability after 18 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.3401308996594916	[1231]	[492,655,354]	3	hSpCas9	negative selection	1704513
58415469	58415492	17	-	26627737	HeLa	viability after 18 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-1.3487147970848659	[475]	[31,14,169]	-8	hSpCas9	negative selection	1704514
58360891	58360914	17	-	26627737	HCT116	viability after 6 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	1.1467288872649222	[479]	[110,197]	6	hSpCas9	negative selection	1786824
58362586	58362609	17	+	26627737	HCT116	viability after 6 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	1.002883585432802	[1336]	[203,540]	5	hSpCas9	negative selection	1786825
58363263	58363286	17	+	26627737	HCT116	viability after 6 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	1.0219359773352843	[963]	[678,102]	5	hSpCas9	negative selection	1786826
58363525	58363548	17	-	26627737	HCT116	viability after 6 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	1.3826894210709686	[333]	[250,73]	7	hSpCas9	negative selection	1786827
58370997	58371020	17	+	26627737	HCT116	viability after 6 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.6057653962682796	[1505]	[494,285]	3	hSpCas9	negative selection	1786828
58415469	58415492	17	-	26627737	HCT116	viability after 6 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	1.993123410333617	[249]	[198,132]	8	hSpCas9	negative selection	1786829
58360891	58360914	17	-	26627737	HCT116	viability after 8 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.013276032642290686	[251]	[133,119,165]	0	hSpCas9	negative selection	1869139
58362586	58362609	17	+	26627737	HCT116	viability after 8 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.1266835349128148	[600]	[406,275,401]	1	hSpCas9	negative selection	1869140
58363263	58363286	17	+	26627737	HCT116	viability after 8 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.4068443512966522	[477]	[325,356,363]	4	hSpCas9	negative selection	1869141
58363525	58363548	17	-	26627737	HCT116	viability after 8 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	0.09353530256683076	[299]	[194,118,214]	1	hSpCas9	negative selection	1869142
58370997	58371020	17	+	26627737	HCT116	viability after 8 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	-0.13857708852751038	[956]	[396,588,449]	-1	hSpCas9	negative selection	1869143
58415469	58415492	17	-	26627737	HCT116	viability after 8 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.6389485738064302	[223]	[134,41,61]	-7	hSpCas9	negative selection	1869144
58360891	58360914	17	-	26627737	HCT116	viability after 9 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.45064656883448095	[479]	[144,198]	3	hSpCas9	negative selection	1951454
58362586	58362609	17	+	26627737	HCT116	viability after 9 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.20364330582395263	[1336]	[428,396]	1	hSpCas9	negative selection	1951455
58363263	58363286	17	+	26627737	HCT116	viability after 9 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	-0.42212492447676464	[963]	[171,207]	-3	hSpCas9	negative selection	1951456
58363525	58363548	17	-	26627737	HCT116	viability after 9 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	2.400233943470421	[333]	[281,619]	9	hSpCas9	negative selection	1951457
58370997	58371020	17	+	26627737	HCT116	viability after 9 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.3994599287725693	[1505]	[597,476]	3	hSpCas9	negative selection	1951458
58415469	58415492	17	-	26627737	HCT116	viability after 9 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	0.861180449838955	[249]	[237,28]	6	hSpCas9	negative selection	1951459
58360891	58360914	17	-	26627737	HCT116	viability after 12 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.006499457316759327	[251]	[137,105,153]	0	hSpCas9	negative selection	2033769
58362586	58362609	17	+	26627737	HCT116	viability after 12 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.016649563510319876	[600]	[244,357,362]	0	hSpCas9	negative selection	2033770
58363263	58363286	17	+	26627737	HCT116	viability after 12 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.5443213716283299	[477]	[399,487,210]	5	hSpCas9	negative selection	2033771
58363525	58363548	17	-	26627737	HCT116	viability after 12 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	0.36545993280135547	[299]	[302,138,156]	3	hSpCas9	negative selection	2033772
58370997	58371020	17	+	26627737	HCT116	viability after 12 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	-0.056876208985064736	[956]	[369,671,422]	0	hSpCas9	negative selection	2033773
58415469	58415492	17	-	26627737	HCT116	viability after 12 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.8632403426922353	[223]	[42,62,89]	-7	hSpCas9	negative selection	2033774
58360891	58360914	17	-	26627737	HCT116	viability after 15 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.25563503562115364	[251]	[146,178,188]	2	hSpCas9	negative selection	2116084
58362586	58362609	17	+	26627737	HCT116	viability after 15 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	-0.07070646158353278	[600]	[489,222,292]	0	hSpCas9	negative selection	2116085
58363263	58363286	17	+	26627737	HCT116	viability after 15 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.8402869290634021	[477]	[586,482,416]	7	hSpCas9	negative selection	2116086
58363525	58363548	17	-	26627737	HCT116	viability after 15 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	0.05130650343530516	[299]	[206,149,181]	0	hSpCas9	negative selection	2116087
58370997	58371020	17	+	26627737	HCT116	viability after 15 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.07464211856929404	[956]	[376,938,397]	0	hSpCas9	negative selection	2116088
58415469	58415492	17	-	26627737	HCT116	viability after 15 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.9056325411576593	[223]	[93,38,75]	-7	hSpCas9	negative selection	2116089
58360891	58360914	17	-	26627737	HCT116	viability after 18 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.3406935377409267	[251]	[139,115,211]	3	hSpCas9	negative selection	2198399
58362586	58362609	17	+	26627737	HCT116	viability after 18 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.3957481708788049	[600]	[461,321,365]	3	hSpCas9	negative selection	2198400
58363263	58363286	17	+	26627737	HCT116	viability after 18 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.9150150801497585	[477]	[523,409,371]	7	hSpCas9	negative selection	2198401
58363525	58363548	17	-	26627737	HCT116	viability after 18 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	0.7988664506224615	[299]	[257,146,363]	6	hSpCas9	negative selection	2198402
58370997	58371020	17	+	26627737	HCT116	viability after 18 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.4746611636195308	[956]	[563,792,557]	4	hSpCas9	negative selection	2198403
58415469	58415492	17	-	26627737	HCT116	viability after 18 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.3962562870067271	[223]	[129,69,45]	-4	hSpCas9	negative selection	2198404
58415487	58415510	17	-	24336569	HL60	viability	AGGCTTTGGACGCACAGGACTGG	RNF43	ENSG00000108375	0.14388012744756373	[836]	[1956]	1	hSpCas9	negative selection	2290045
58415492	58415515	17	-	24336569	HL60	viability	CAGGCAGGCTTTGGACGCACAGG	RNF43	ENSG00000108375	0.570612595950797	[580]	[1825]	5	hSpCas9	negative selection	2290046
58415497	58415520	17	+	24336569	HL60	viability	GCGTCCAAAGCCTGCCTGCAGGG	RNF43	ENSG00000108375	0.8526713311705041	[576]	[2204]	7	hSpCas9	negative selection	2290047
58415507	58415530	17	-	24336569	HL60	viability	CTGATGGCTACCCTGCAGGCAGG	RNF43	ENSG00000108375	-3.845229754138818	[162]	[23]	-9	hSpCas9	negative selection	2290048
58415515	58415538	17	+	24336569	HL60	viability	CAGGGTAGCCATCAGCAGCCAGG	RNF43	ENSG00000108375	0.41389256316168554	[785]	[2215]	4	hSpCas9	negative selection	2290049
58415523	58415546	17	+	24336569	HL60	viability	CCATCAGCAGCCAGGGCCAGAGG	RNF43	ENSG00000108375	0.9033165117536646	[404]	[1602]	7	hSpCas9	negative selection	2290050
58415539	58415562	17	-	24336569	HL60	viability	AGCTGCAGCTGGCTGCCCTCTGG	RNF43	ENSG00000108375	0.4684159409368145	[110]	[324]	4	hSpCas9	negative selection	2290051
58415544	58415567	17	+	24336569	HL60	viability	GGGCAGCCAGCTGCAGCTGGTGG	RNF43	ENSG00000108375	0.7349020627236764	[227]	[802]	6	hSpCas9	negative selection	2290052
58415550	58415573	17	-	24336569	HL60	viability	TGGTGGCCACCAGCTGCAGCTGG	RNF43	ENSG00000108375	0.12609855817678128	[907]	[2096]	1	hSpCas9	negative selection	2290053
58415567	58415590	17	-	24336569	HL60	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-0.8354027733988159	[1709]	[2027]	-6	hSpCas9	negative selection	2290054
58415487	58415510	17	-	24336569	KBM7	viability	AGGCTTTGGACGCACAGGACTGG	RNF43	ENSG00000108375	0.4614221456554435	[682]	[2564]	4	hSpCas9	negative selection	2357222
58415492	58415515	17	-	24336569	KBM7	viability	CAGGCAGGCTTTGGACGCACAGG	RNF43	ENSG00000108375	-0.14287375390940305	[690]	[1706]	-1	hSpCas9	negative selection	2357223
58415497	58415520	17	+	24336569	KBM7	viability	GCGTCCAAAGCCTGCCTGCAGGG	RNF43	ENSG00000108375	0.8826217820259856	[312]	[1573]	7	hSpCas9	negative selection	2357224
58415507	58415530	17	-	24336569	KBM7	viability	CTGATGGCTACCCTGCAGGCAGG	RNF43	ENSG00000108375	2.2438342458029163	[36]	[477]	9	hSpCas9	negative selection	2357225
58415515	58415538	17	+	24336569	KBM7	viability	CAGGGTAGCCATCAGCAGCCAGG	RNF43	ENSG00000108375	0.31378774110745844	[468]	[1589]	3	hSpCas9	negative selection	2357226
58415523	58415546	17	+	24336569	KBM7	viability	CCATCAGCAGCCAGGGCCAGAGG	RNF43	ENSG00000108375	0.4814848966401721	[494]	[1884]	4	hSpCas9	negative selection	2357227
58415539	58415562	17	-	24336569	KBM7	viability	AGCTGCAGCTGGCTGCCCTCTGG	RNF43	ENSG00000108375	1.411721940541376	[112]	[819]	9	hSpCas9	negative selection	2357228
58415544	58415567	17	+	24336569	KBM7	viability	GGGCAGCCAGCTGCAGCTGGTGG	RNF43	ENSG00000108375	-0.8669556315520639	[221]	[331]	-6	hSpCas9	negative selection	2357229
58415550	58415573	17	-	24336569	KBM7	viability	TGGTGGCCACCAGCTGCAGCTGG	RNF43	ENSG00000108375	0.7294472630386408	[652]	[2952]	6	hSpCas9	negative selection	2357230
58415567	58415590	17	-	24336569	KBM7	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	0.21927923187055476	[1226]	[3895]	2	hSpCas9	negative selection	2357231
58415481	58415504	17	-	27260157	DLD1	viability	TGGACGCACAGGACTGGTACTGG	RNF43	ENSG00000108375	0.861821359680145	[]	[]	9	hSpCas9	negative selection	2573831
58370907	58370930	17	+	27260157	DLD1	viability	CTACCTTGCTAGCCAGTGACAGG	RNF43	ENSG00000108375	0.251963250840397	[]	[]	4	hSpCas9	negative selection	2575976
58363337	58363360	17	-	27260157	DLD1	viability	TAATGACGCTGAGAAGCTGATGG	RNF43	ENSG00000108375	0.301298808525949	[]	[]	4	hSpCas9	negative selection	2578453
58415487	58415510	17	-	27260157	DLD1	viability	AGGCTTTGGACGCACAGGACTGG	RNF43	ENSG00000108375	0.31311754614683	[]	[]	4	hSpCas9	negative selection	2578998
58415492	58415515	17	-	27260157	DLD1	viability	CAGGCAGGCTTTGGACGCACAGG	RNF43	ENSG00000108375	0.0283673845788363	[]	[]	0	hSpCas9	negative selection	2583051
58415567	58415590	17	-	27260157	DLD1	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-0.234083071131568	[]	[]	-2	hSpCas9	negative selection	2584871
58370981	58371004	17	-	27260157	DLD1	viability	GATGACGACAATCTGGAGCCTGG	RNF43	ENSG00000108375	1.31373969313959	[]	[]	9	hSpCas9	negative selection	2585524
58415523	58415546	17	+	27260157	DLD1	viability	CCATCAGCAGCCAGGGCCAGAGG	RNF43	ENSG00000108375	0.559613665656903	[]	[]	8	hSpCas9	negative selection	2586518
58415515	58415538	17	+	27260157	DLD1	viability	CAGGGTAGCCATCAGCAGCCAGG	RNF43	ENSG00000108375	0.875671220513107	[]	[]	9	hSpCas9	negative selection	2605769
58362611	58362634	17	-	27260157	DLD1	viability	TGGATCCTAATGACAGTGGTGGG	RNF43	ENSG00000108375	0.929403127184808	[]	[]	9	hSpCas9	negative selection	2608618
58415550	58415573	17	-	27260157	DLD1	viability	TGGTGGCCACCAGCTGCAGCTGG	RNF43	ENSG00000108375	0.557348369868926	[]	[]	8	hSpCas9	negative selection	2609883
58415507	58415530	17	-	27260157	DLD1	viability	CTGATGGCTACCCTGCAGGCAGG	RNF43	ENSG00000108375	0.900596308077304	[]	[]	9	hSpCas9	negative selection	2612163
58415544	58415567	17	+	27260157	DLD1	viability	GGGCAGCCAGCTGCAGCTGGTGG	RNF43	ENSG00000108375	-0.868651108051666	[]	[]	-6	hSpCas9	negative selection	2616632
58415469	58415492	17	-	27260157	DLD1	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-1.01368702621768	[]	[]	-7	hSpCas9	negative selection	2617335
58415496	58415519	17	+	27260157	DLD1	viability	TGCGTCCAAAGCCTGCCTGCAGG	RNF43	ENSG00000108375	-0.623265683395277	[]	[]	-5	hSpCas9	negative selection	2619484
58415539	58415562	17	-	27260157	DLD1	viability	AGCTGCAGCTGGCTGCCCTCTGG	RNF43	ENSG00000108375	1.26768363546811	[]	[]	9	hSpCas9	negative selection	2619756
58415497	58415520	17	+	27260157	DLD1	viability	GCGTCCAAAGCCTGCCTGCAGGG	RNF43	ENSG00000108375	2.34785624821688	[]	[]	9	hSpCas9	negative selection	2621116
58370997	58371020	17	+	27260157	DLD1	viability	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	-1.36075865305005	[]	[]	-8	hSpCas9	negative selection	2642051
58370958	58370981	17	-	27260157	DLD1	viability	ATTCATCAGCATCGTCAAGCTGG	RNF43	ENSG00000108375	0.98844457473383	[]	[]	9	hSpCas9	negative selection	2644708
58363578	58363601	17	-	27260157	DLD1	viability	GCTCGGATGGCGGGTGAGCGAGG	RNF43	ENSG00000108375	-0.234404345116782	[]	[]	-2	hSpCas9	negative selection	2646676
58415481	58415504	17	-	27260157	HT1080	viability	TGGACGCACAGGACTGGTACTGG	RNF43	ENSG00000108375	0.91339066157692	[]	[]	7	hSpCas9	negative selection	2649961
58370907	58370930	17	+	27260157	HT1080	viability	CTACCTTGCTAGCCAGTGACAGG	RNF43	ENSG00000108375	0.0206088366917477	[]	[]	0	hSpCas9	negative selection	2652106
58363337	58363360	17	-	27260157	HT1080	viability	TAATGACGCTGAGAAGCTGATGG	RNF43	ENSG00000108375	-0.0140795299588679	[]	[]	0	hSpCas9	negative selection	2654583
58415487	58415510	17	-	27260157	HT1080	viability	AGGCTTTGGACGCACAGGACTGG	RNF43	ENSG00000108375	0.359206736291925	[]	[]	3	hSpCas9	negative selection	2655128
58415492	58415515	17	-	27260157	HT1080	viability	CAGGCAGGCTTTGGACGCACAGG	RNF43	ENSG00000108375	-1.36535072207141	[]	[]	-9	hSpCas9	negative selection	2659181
58415567	58415590	17	-	27260157	HT1080	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-0.137849325355888	[]	[]	0	hSpCas9	negative selection	2661001
58370981	58371004	17	-	27260157	HT1080	viability	GATGACGACAATCTGGAGCCTGG	RNF43	ENSG00000108375	1.42110168732006	[]	[]	9	hSpCas9	negative selection	2661654
58415523	58415546	17	+	27260157	HT1080	viability	CCATCAGCAGCCAGGGCCAGAGG	RNF43	ENSG00000108375	0.456023891457501	[]	[]	4	hSpCas9	negative selection	2662648
58415515	58415538	17	+	27260157	HT1080	viability	CAGGGTAGCCATCAGCAGCCAGG	RNF43	ENSG00000108375	-0.358778094185125	[]	[]	-7	hSpCas9	negative selection	2681899
58362611	58362634	17	-	27260157	HT1080	viability	TGGATCCTAATGACAGTGGTGGG	RNF43	ENSG00000108375	0.469226959241339	[]	[]	4	hSpCas9	negative selection	2684748
58415550	58415573	17	-	27260157	HT1080	viability	TGGTGGCCACCAGCTGCAGCTGG	RNF43	ENSG00000108375	-0.193321824904512	[]	[]	0	hSpCas9	negative selection	2686013
58415507	58415530	17	-	27260157	HT1080	viability	CTGATGGCTACCCTGCAGGCAGG	RNF43	ENSG00000108375	0.810172131603539	[]	[]	7	hSpCas9	negative selection	2688293
58415544	58415567	17	+	27260157	HT1080	viability	GGGCAGCCAGCTGCAGCTGGTGG	RNF43	ENSG00000108375	-0.898663968959254	[]	[]	-8	hSpCas9	negative selection	2692762
58415469	58415492	17	-	27260157	HT1080	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.375962248327467	[]	[]	-7	hSpCas9	negative selection	2693465
58415496	58415519	17	+	27260157	HT1080	viability	TGCGTCCAAAGCCTGCCTGCAGG	RNF43	ENSG00000108375	1.07447159119634	[]	[]	8	hSpCas9	negative selection	2695614
58415539	58415562	17	-	27260157	HT1080	viability	AGCTGCAGCTGGCTGCCCTCTGG	RNF43	ENSG00000108375	1.49689475379939	[]	[]	9	hSpCas9	negative selection	2695886
58415497	58415520	17	+	27260157	HT1080	viability	GCGTCCAAAGCCTGCCTGCAGGG	RNF43	ENSG00000108375	0.640603942344524	[]	[]	5	hSpCas9	negative selection	2697246
58370997	58371020	17	+	27260157	HT1080	viability	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	-0.888274972590894	[]	[]	-8	hSpCas9	negative selection	2718181
58370958	58370981	17	-	27260157	HT1080	viability	ATTCATCAGCATCGTCAAGCTGG	RNF43	ENSG00000108375	0.119107115595774	[]	[]	1	hSpCas9	negative selection	2720838
58363578	58363601	17	-	27260157	HT1080	viability	GCTCGGATGGCGGGTGAGCGAGG	RNF43	ENSG00000108375	0.0514092375653106	[]	[]	0	hSpCas9	negative selection	2722806
58415481	58415504	17	-	27260157	MKN45	viability	TGGACGCACAGGACTGGTACTGG	RNF43	ENSG00000108375	0.977158988022278	[]	[]	8	hSpCas9	negative selection	2726091
58370907	58370930	17	+	27260157	MKN45	viability	CTACCTTGCTAGCCAGTGACAGG	RNF43	ENSG00000108375	1.35771216197109	[]	[]	9	hSpCas9	negative selection	2728236
58363337	58363360	17	-	27260157	MKN45	viability	TAATGACGCTGAGAAGCTGATGG	RNF43	ENSG00000108375	-0.0200673990851564	[]	[]	0	hSpCas9	negative selection	2730713
58415487	58415510	17	-	27260157	MKN45	viability	AGGCTTTGGACGCACAGGACTGG	RNF43	ENSG00000108375	0.796348705484493	[]	[]	7	hSpCas9	negative selection	2731258
58415492	58415515	17	-	27260157	MKN45	viability	CAGGCAGGCTTTGGACGCACAGG	RNF43	ENSG00000108375	-0.0855935348396904	[]	[]	0	hSpCas9	negative selection	2735311
58415567	58415590	17	-	27260157	MKN45	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	0.260587572929817	[]	[]	5	hSpCas9	negative selection	2737131
58370981	58371004	17	-	27260157	MKN45	viability	GATGACGACAATCTGGAGCCTGG	RNF43	ENSG00000108375	1.50174094943365	[]	[]	9	hSpCas9	negative selection	2737784
58415523	58415546	17	+	27260157	MKN45	viability	CCATCAGCAGCCAGGGCCAGAGG	RNF43	ENSG00000108375	-0.203745902856014	[]	[]	0	hSpCas9	negative selection	2738778
58415515	58415538	17	+	27260157	MKN45	viability	CAGGGTAGCCATCAGCAGCCAGG	RNF43	ENSG00000108375	0.793053860484749	[]	[]	7	hSpCas9	negative selection	2758029
58362611	58362634	17	-	27260157	MKN45	viability	TGGATCCTAATGACAGTGGTGGG	RNF43	ENSG00000108375	1.95711365643463	[]	[]	9	hSpCas9	negative selection	2760878
58415550	58415573	17	-	27260157	MKN45	viability	TGGTGGCCACCAGCTGCAGCTGG	RNF43	ENSG00000108375	0.692308039442167	[]	[]	7	hSpCas9	negative selection	2762143
58415507	58415530	17	-	27260157	MKN45	viability	CTGATGGCTACCCTGCAGGCAGG	RNF43	ENSG00000108375	0.834791161058846	[]	[]	8	hSpCas9	negative selection	2764423
58415544	58415567	17	+	27260157	MKN45	viability	GGGCAGCCAGCTGCAGCTGGTGG	RNF43	ENSG00000108375	0.203210003212752	[]	[]	5	hSpCas9	negative selection	2768892
58415469	58415492	17	-	27260157	MKN45	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.76812005030297	[]	[]	-7	hSpCas9	negative selection	2769595
58415496	58415519	17	+	27260157	MKN45	viability	TGCGTCCAAAGCCTGCCTGCAGG	RNF43	ENSG00000108375	0.820744031328248	[]	[]	8	hSpCas9	negative selection	2771744
58415539	58415562	17	-	27260157	MKN45	viability	AGCTGCAGCTGGCTGCCCTCTGG	RNF43	ENSG00000108375	1.45760515867781	[]	[]	9	hSpCas9	negative selection	2772016
58415497	58415520	17	+	27260157	MKN45	viability	GCGTCCAAAGCCTGCCTGCAGGG	RNF43	ENSG00000108375	1.88710982409457	[]	[]	9	hSpCas9	negative selection	2773376
58370997	58371020	17	+	27260157	MKN45	viability	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.183169806116839	[]	[]	5	hSpCas9	negative selection	2794311
58370958	58370981	17	-	27260157	MKN45	viability	ATTCATCAGCATCGTCAAGCTGG	RNF43	ENSG00000108375	0.992347920187272	[]	[]	8	hSpCas9	negative selection	2796968
58363578	58363601	17	-	27260157	MKN45	viability	GCTCGGATGGCGGGTGAGCGAGG	RNF43	ENSG00000108375	-0.118245306092151	[]	[]	0	hSpCas9	negative selection	2798936
58415481	58415504	17	-	27260157	RKO	viability	TGGACGCACAGGACTGGTACTGG	RNF43	ENSG00000108375	0.934327829427604	[]	[]	8	hSpCas9	negative selection	2802221
58370907	58370930	17	+	27260157	RKO	viability	CTACCTTGCTAGCCAGTGACAGG	RNF43	ENSG00000108375	0.51529711493137	[]	[]	2	hSpCas9	negative selection	2804366
58363337	58363360	17	-	27260157	RKO	viability	TAATGACGCTGAGAAGCTGATGG	RNF43	ENSG00000108375	0.117190642550413	[]	[]	0	hSpCas9	negative selection	2806843
58415487	58415510	17	-	27260157	RKO	viability	AGGCTTTGGACGCACAGGACTGG	RNF43	ENSG00000108375	1.02133152336806	[]	[]	9	hSpCas9	negative selection	2807388
58415492	58415515	17	-	27260157	RKO	viability	CAGGCAGGCTTTGGACGCACAGG	RNF43	ENSG00000108375	-0.262539503095414	[]	[]	-1	hSpCas9	negative selection	2811441
58415567	58415590	17	-	27260157	RKO	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-1.36255689360183	[]	[]	-8	hSpCas9	negative selection	2813261
58370981	58371004	17	-	27260157	RKO	viability	GATGACGACAATCTGGAGCCTGG	RNF43	ENSG00000108375	1.07227923997239	[]	[]	9	hSpCas9	negative selection	2813914
58415523	58415546	17	+	27260157	RKO	viability	CCATCAGCAGCCAGGGCCAGAGG	RNF43	ENSG00000108375	-0.0539416703321272	[]	[]	0	hSpCas9	negative selection	2814908
58415515	58415538	17	+	27260157	RKO	viability	CAGGGTAGCCATCAGCAGCCAGG	RNF43	ENSG00000108375	0.106376326502229	[]	[]	0	hSpCas9	negative selection	2834159
58362611	58362634	17	-	27260157	RKO	viability	TGGATCCTAATGACAGTGGTGGG	RNF43	ENSG00000108375	0.244604770306308	[]	[]	1	hSpCas9	negative selection	2837008
58415550	58415573	17	-	27260157	RKO	viability	TGGTGGCCACCAGCTGCAGCTGG	RNF43	ENSG00000108375	-0.267770409925788	[]	[]	-1	hSpCas9	negative selection	2838273
58415507	58415530	17	-	27260157	RKO	viability	CTGATGGCTACCCTGCAGGCAGG	RNF43	ENSG00000108375	0.467667528511996	[]	[]	2	hSpCas9	negative selection	2840553
58415544	58415567	17	+	27260157	RKO	viability	GGGCAGCCAGCTGCAGCTGGTGG	RNF43	ENSG00000108375	0.0265152302023245	[]	[]	0	hSpCas9	negative selection	2845022
58415469	58415492	17	-	27260157	RKO	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.00742951213164572	[]	[]	0	hSpCas9	negative selection	2845725
58415496	58415519	17	+	27260157	RKO	viability	TGCGTCCAAAGCCTGCCTGCAGG	RNF43	ENSG00000108375	0.0147108518737167	[]	[]	0	hSpCas9	negative selection	2847874
58415539	58415562	17	-	27260157	RKO	viability	AGCTGCAGCTGGCTGCCCTCTGG	RNF43	ENSG00000108375	0.457531085734761	[]	[]	2	hSpCas9	negative selection	2848146
58415497	58415520	17	+	27260157	RKO	viability	GCGTCCAAAGCCTGCCTGCAGGG	RNF43	ENSG00000108375	1.23171342403871	[]	[]	9	hSpCas9	negative selection	2849506
58370997	58371020	17	+	27260157	RKO	viability	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	-0.73657895021879	[]	[]	-7	hSpCas9	negative selection	2870441
58370958	58370981	17	-	27260157	RKO	viability	ATTCATCAGCATCGTCAAGCTGG	RNF43	ENSG00000108375	0.864871913302896	[]	[]	8	hSpCas9	negative selection	2873098
58363578	58363601	17	-	27260157	RKO	viability	GCTCGGATGGCGGGTGAGCGAGG	RNF43	ENSG00000108375	0.970758174541165	[]	[]	8	hSpCas9	negative selection	2875066
58415481	58415504	17	-	27260157	SF268	viability	TGGACGCACAGGACTGGTACTGG	RNF43	ENSG00000108375	1.08239247578492	[]	[]	9	hSpCas9	negative selection	2878351
58370907	58370930	17	+	27260157	SF268	viability	CTACCTTGCTAGCCAGTGACAGG	RNF43	ENSG00000108375	-0.0336630988809352	[]	[]	0	hSpCas9	negative selection	2880496
58363337	58363360	17	-	27260157	SF268	viability	TAATGACGCTGAGAAGCTGATGG	RNF43	ENSG00000108375	0.0386455529313056	[]	[]	0	hSpCas9	negative selection	2882973
58415487	58415510	17	-	27260157	SF268	viability	AGGCTTTGGACGCACAGGACTGG	RNF43	ENSG00000108375	0.729471584219049	[]	[]	8	hSpCas9	negative selection	2883518
58415492	58415515	17	-	27260157	SF268	viability	CAGGCAGGCTTTGGACGCACAGG	RNF43	ENSG00000108375	-0.520437233848968	[]	[]	-4	hSpCas9	negative selection	2887571
58415567	58415590	17	-	27260157	SF268	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	0.521255356272555	[]	[]	8	hSpCas9	negative selection	2889391
58370981	58371004	17	-	27260157	SF268	viability	GATGACGACAATCTGGAGCCTGG	RNF43	ENSG00000108375	0.981551396389883	[]	[]	9	hSpCas9	negative selection	2890044
58415523	58415546	17	+	27260157	SF268	viability	CCATCAGCAGCCAGGGCCAGAGG	RNF43	ENSG00000108375	0.455932727081512	[]	[]	7	hSpCas9	negative selection	2891038
58415515	58415538	17	+	27260157	SF268	viability	CAGGGTAGCCATCAGCAGCCAGG	RNF43	ENSG00000108375	0.52715131897057	[]	[]	8	hSpCas9	negative selection	2910289
58362611	58362634	17	-	27260157	SF268	viability	TGGATCCTAATGACAGTGGTGGG	RNF43	ENSG00000108375	0.850280858451416	[]	[]	9	hSpCas9	negative selection	2913138
58415550	58415573	17	-	27260157	SF268	viability	TGGTGGCCACCAGCTGCAGCTGG	RNF43	ENSG00000108375	-1.14273108001145	[]	[]	-7	hSpCas9	negative selection	2914403
58415507	58415530	17	-	27260157	SF268	viability	CTGATGGCTACCCTGCAGGCAGG	RNF43	ENSG00000108375	1.04875780417195	[]	[]	9	hSpCas9	negative selection	2916683
58415544	58415567	17	+	27260157	SF268	viability	GGGCAGCCAGCTGCAGCTGGTGG	RNF43	ENSG00000108375	0.294973434365218	[]	[]	4	hSpCas9	negative selection	2921152
58415469	58415492	17	-	27260157	SF268	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.140072358393277	[]	[]	-1	hSpCas9	negative selection	2921855
58415496	58415519	17	+	27260157	SF268	viability	TGCGTCCAAAGCCTGCCTGCAGG	RNF43	ENSG00000108375	-0.210875081911262	[]	[]	-2	hSpCas9	negative selection	2924004
58415539	58415562	17	-	27260157	SF268	viability	AGCTGCAGCTGGCTGCCCTCTGG	RNF43	ENSG00000108375	1.22433189888452	[]	[]	9	hSpCas9	negative selection	2924276
58415497	58415520	17	+	27260157	SF268	viability	GCGTCCAAAGCCTGCCTGCAGGG	RNF43	ENSG00000108375	1.874427841037	[]	[]	9	hSpCas9	negative selection	2925636
58370997	58371020	17	+	27260157	SF268	viability	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.969486582664445	[]	[]	9	hSpCas9	negative selection	2946571
58370958	58370981	17	-	27260157	SF268	viability	ATTCATCAGCATCGTCAAGCTGG	RNF43	ENSG00000108375	0.599190481400377	[]	[]	8	hSpCas9	negative selection	2949228
58363578	58363601	17	-	27260157	SF268	viability	GCTCGGATGGCGGGTGAGCGAGG	RNF43	ENSG00000108375	0.205339562424259	[]	[]	3	hSpCas9	negative selection	2951196
58360917	58360940	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTCAGCAGAGAACAGCCTGGG	RNF43	ENSG00000108375	0.08623253334008399	[3,3]	[3,2]	1	hSpCas9	positive selection	3017378
58358781	58358804	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAAGATCGAGAGGGTCCCAGGG	RNF43	ENSG00000108375	-0.37006745922022943	[3,2]	[1,1]	-5	hSpCas9	positive selection	3017379
58363313	58363336	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTTGTGTACAAGAACCAAAAGG	RNF43	ENSG00000108375	0.343012999288634	[4,4]	[4,5]	7	hSpCas9	positive selection	3017380
58360891	58360914	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.6332711694055341	[3,2]	[3,5]	9	hSpCas9	positive selection	3017381
58360917	58360940	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTCAGCAGAGAACAGCCTGGG	RNF43	ENSG00000108375	-0.5478011443940325	[3,3]	[2,0]	-7	hSpCas9	positive selection	3085236
58358781	58358804	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAAGATCGAGAGGGTCCCAGGG	RNF43	ENSG00000108375	-0.2777116799345053	[3,3]	[2,0]	-4	hSpCas9	positive selection	3085237
58363313	58363336	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTTGTGTACAAGAACCAAAAGG	RNF43	ENSG00000108375	0.1644915407922531	[4,4]	[5,2]	3	hSpCas9	positive selection	3085238
58360891	58360914	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.1215934065343687	[3,3]	[2,1]	-2	hSpCas9	positive selection	3085239
58363264	58363287		+	24336571	A375	resistance to PLX after 7 days	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	0.097428950117297	[13,9]	[11,12]	3	hSpCas9	positive selection	3141434
58362588	58362611		-	24336571	A375	resistance to PLX after 7 days	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.4031401685329361	[31,28]	[37,41]	8	hSpCas9	positive selection	3141435
58362606	58362629		+	24336571	A375	resistance to PLX after 7 days	TGGTGCCCACCACTGTCATTAGG	RNF43	ENSG00000108375	-0.25043015991492523	[9,9]	[7,7]	-7	hSpCas9	positive selection	3141436
58363357	58363380		+	24336571	A375	resistance to PLX after 7 days	TTACCCCAGATCAACACCACTGG	RNF43	ENSG00000108375	-0.08393261181913236	[11,12]	[10,11]	-2	hSpCas9	positive selection	3141437
58363264	58363287		+	24336571	A375	resistance to PLX after 14 days	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.37579134152435734	[10,14]	[3,3]	-4	hSpCas9	positive selection	3199227
58362588	58362611		-	24336571	A375	resistance to PLX after 14 days	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	1.479945947128524	[26,31]	[36,40]	9	hSpCas9	positive selection	3199228
58362606	58362629		+	24336571	A375	resistance to PLX after 14 days	TGGTGCCCACCACTGTCATTAGG	RNF43	ENSG00000108375	0.793687625194029	[8,8]	[5,7]	6	hSpCas9	positive selection	3199229
58363357	58363380		+	24336571	A375	resistance to PLX after 14 days	TTACCCCAGATCAACACCACTGG	RNF43	ENSG00000108375	0.0669452794977548	[12,16]	[5,7]	0	hSpCas9	positive selection	3199230
58363264	58363287		+	24336571	A375	viability after 7 days	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	0.03351679444858191	[11]	[13,9]	0	hSpCas9	negative selection	3257020
58362588	58362611		-	24336571	A375	viability after 7 days	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	-0.2952143478212408	[38]	[31,28]	-4	hSpCas9	negative selection	3257021
58362606	58362629		+	24336571	A375	viability after 7 days	TGGTGCCCACCACTGTCATTAGG	RNF43	ENSG00000108375	1.3540698527264992	[3]	[9,9]	9	hSpCas9	negative selection	3257022
58363357	58363380		+	24336571	A375	viability after 7 days	TTACCCCAGATCAACACCACTGG	RNF43	ENSG00000108375	-0.468101614242604	[17]	[11,12]	-6	hSpCas9	negative selection	3257023
58363264	58363287		+	24336571	A375	viability after 14 days	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	0.16582785660220462	[11]	[10,14]	2	hSpCas9	negative selection	3314813
58362588	58362611		-	24336571	A375	viability after 14 days	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	-0.3212042299007234	[38]	[26,31]	-4	hSpCas9	negative selection	3314814
58362606	58362629		+	24336571	A375	viability after 14 days	TGGTGCCCACCACTGTCATTAGG	RNF43	ENSG00000108375	1.1391431559576903	[3]	[8,8]	9	hSpCas9	negative selection	3314815
58363357	58363380		+	24336571	A375	viability after 14 days	TTACCCCAGATCAACACCACTGG	RNF43	ENSG00000108375	-0.20283079705498813	[17]	[12,16]	-2	hSpCas9	negative selection	3314816
58360918	58360941	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.38696149186243056	[116,116]	[0,0]	2	hSpCas9	positive selection	3390244
58363289	58363312	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.7233476394434837	[277,277]	[2,2]	3	hSpCas9	positive selection	3390245
58360803	58360826	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	-2.128536189195626	[668,668]	[0,0]	-9	hSpCas9	positive selection	3390246
58360917	58360940	17	-	26780180	HT29	viability (Avana library 4 designs)	GCTTCAGCAGAGAACAGCCTGGG	RNF43	ENSG00000108375	-0.238153503818549	[]	[]	-4	hSpCas9	negative selection	3455759
58358780	58358803	17	+	26780180	HT29	viability (Avana library 4 designs)	GTAAGATCGAGAGGGTCCCAGGG	RNF43	ENSG00000108375	2.08943954840441	[]	[]	7	hSpCas9	negative selection	3455760
58363313	58363336	17	-	26780180	HT29	viability (Avana library 4 designs)	GTTTGTGTACAAGAACCAAAAGG	RNF43	ENSG00000108375	-0.0572236766704918	[]	[]	-1	hSpCas9	negative selection	3455761
58360891	58360914	17	-	26780180	HT29	viability (Avana library 4 designs)	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.522368867941508	[]	[]	2	hSpCas9	negative selection	3455762
58363313	58363336	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTTGTGTACAAGAACCAAAAGG	RNF43	ENSG00000108375	-4.68483943874509	[]	[]	-5	hSpCas9	negative selection	3553899
58358780	58358803	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAAGATCGAGAGGGTCCCAGGG	RNF43	ENSG00000108375	1.99755185362064	[]	[]	3	hSpCas9	negative selection	3553900
58360891	58360914	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	1.78822454419853	[]	[]	2	hSpCas9	negative selection	3553901
58360917	58360940	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCAGCAGAGAACAGCCTGGG	RNF43	ENSG00000108375	0.777521432930449	[]	[]	1	hSpCas9	negative selection	3553902
58415524	58415547	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATCAGCAGCCAGGGCCAGAGGG	RNF43	ENSG00000108375	4.94698947363834	[]	[]	8	hSpCas9	negative selection	3553903
58363290	58363313	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCAGCTCAATCCTCACATGGG	RNF43	ENSG00000108375	0.335595512819934	[]	[]	0	hSpCas9	negative selection	3553904
58363313	58363336	17	-	26780180	A375	viability (Avana lentiGuide)	GTTTGTGTACAAGAACCAAAAGG	RNF43	ENSG00000108375	-5.21045683395923	[]	[]	-8	hSpCas9	negative selection	3662558
58358780	58358803	17	+	26780180	A375	viability (Avana lentiGuide)	GTAAGATCGAGAGGGTCCCAGGG	RNF43	ENSG00000108375	0.241235294742105	[]	[]	0	hSpCas9	negative selection	3662559
58360891	58360914	17	-	26780180	A375	viability (Avana lentiGuide)	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	9.93546773413343	[]	[]	6	hSpCas9	negative selection	3662560
58360917	58360940	17	-	26780180	A375	viability (Avana lentiGuide)	GCTTCAGCAGAGAACAGCCTGGG	RNF43	ENSG00000108375	-0.739278080965969	[]	[]	-1	hSpCas9	negative selection	3662561
58415524	58415547	17	+	26780180	A375	viability (Avana lentiGuide)	CATCAGCAGCCAGGGCCAGAGGG	RNF43	ENSG00000108375	3.76554298517483	[]	[]	3	hSpCas9	negative selection	3662562
58363290	58363313	17	+	26780180	A375	viability (Avana lentiGuide)	CTTCAGCTCAATCCTCACATGGG	RNF43	ENSG00000108375	0.530839952713754	[]	[]	0	hSpCas9	negative selection	3662563
58363313	58363336	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTTGTGTACAAGAACCAAAAGG	RNF43	ENSG00000108375	-0.28905955693375146	[7]	[5,4]	-4	hSpCas9	positive selection	3771165
58358780	58358803	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAAGATCGAGAGGGTCCCAGGG	RNF43	ENSG00000108375	-0.1182531010112499	[4]	[4,3]	-2	hSpCas9	positive selection	3771166
58360891	58360914	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.14640734968585922	[4]	[4,4]	4	hSpCas9	positive selection	3771167
58360917	58360940	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCAGCAGAGAACAGCCTGGG	RNF43	ENSG00000108375	-0.047586364045805796	[4]	[3,4]	-1	hSpCas9	positive selection	3771168
58415524	58415547	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCAGCAGCCAGGGCCAGAGGG	RNF43	ENSG00000108375	0.290458171300759	[4]	[5,4]	8	hSpCas9	positive selection	3771169
58363290	58363313	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCAGCTCAATCCTCACATGGG	RNF43	ENSG00000108375	-0.15128387659409814	[6]	[6,4]	-2	hSpCas9	positive selection	3771170
58363313	58363336	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTTGTGTACAAGAACCAAAAGG	RNF43	ENSG00000108375	0.32150190907596704	[6]	[6,6]	8	hSpCas9	positive selection	3879772
58358780	58358803	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAAGATCGAGAGGGTCCCAGGG	RNF43	ENSG00000108375	-0.05039796893761178	[5]	[3,4]	0	hSpCas9	positive selection	3879773
58360891	58360914	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.4454245836469257	[5]	[3,2]	-5	hSpCas9	positive selection	3879774
58360917	58360940	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCAGCAGAGAACAGCCTGGG	RNF43	ENSG00000108375	0.03536855560967956	[5]	[4,3]	0	hSpCas9	positive selection	3879775
58415524	58415547	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCAGCAGCCAGGGCCAGAGGG	RNF43	ENSG00000108375	0.2929041443416387	[5]	[4,5]	7	hSpCas9	positive selection	3879776
58363290	58363313	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCAGCTCAATCCTCACATGGG	RNF43	ENSG00000108375	0.16412750125066178	[7]	[8,6]	4	hSpCas9	positive selection	3879777
58363264	58363287	17	+	26780180	A375	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	1.67995122957628	[]	[]	9	hSpCas9	negative selection	3989892
58362588	58362611	17	-	26780180	A375	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.769399819515348	[]	[]	3	hSpCas9	negative selection	3989893
58363289	58363312	17	-	26780180	A375	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.777631095717763	[]	[]	3	hSpCas9	negative selection	3989894
58360803	58360826	17	-	26780180	A375	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	1.09333922477717	[]	[]	5	hSpCas9	negative selection	3989895
58360918	58360941	17	-	26780180	A375	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.775703417192701	[]	[]	3	hSpCas9	negative selection	3989896
58362570	58362593	17	+	26780180	A375	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.615227784754134	[]	[]	2	hSpCas9	negative selection	3989897
58363264	58363287	17	+	26780180	HT29	viability (GeCKOv2 library)	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	1.94378810639653	[]	[]	9	hSpCas9	negative selection	4097858
58362588	58362611	17	-	26780180	HT29	viability (GeCKOv2 library)	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	1.11738382930962	[]	[]	5	hSpCas9	negative selection	4097859
58363289	58363312	17	-	26780180	HT29	viability (GeCKOv2 library)	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.723952539088896	[]	[]	2	hSpCas9	negative selection	4097860
58360803	58360826	17	-	26780180	HT29	viability (GeCKOv2 library)	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.963851805037477	[]	[]	4	hSpCas9	negative selection	4097861
58360918	58360941	17	-	26780180	HT29	viability (GeCKOv2 library)	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	1.28482956706002	[]	[]	6	hSpCas9	negative selection	4097862
58362570	58362593	17	+	26780180	HT29	viability (GeCKOv2 library)	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.978129816539943	[]	[]	4	hSpCas9	negative selection	4097863
58363264	58363287	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.21295583441658217	[4]	[2,1]	-5	hSpCas9	positive selection	4166972
58362588	58362611	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.33106774059658084	[4]	[2,5]	7	hSpCas9	positive selection	4166973
58362606	58362629	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGTGCCCACCACTGTCATTAGG	RNF43	ENSG00000108375	0.049075706985250545	[4]	[3,2]	1	hSpCas9	positive selection	4166974
58363357	58363380	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTACCCCAGATCAACACCACTGG	RNF43	ENSG00000108375	0.40871274191544066	[3]	[3,2]	8	hSpCas9	positive selection	4166975
58363264	58363287	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.3041281204569859	[2]	[0,1,0,0]	-4	hSpCas9	positive selection	4230994
58362588	58362611	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.028359987227783212	[4]	[5,0,1,0]	0	hSpCas9	positive selection	4230995
58362606	58362629	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGTGCCCACCACTGTCATTAGG	RNF43	ENSG00000108375	0.42767046741293707	[4]	[5,4,2,0]	3	hSpCas9	positive selection	4230996
58363357	58363380	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTACCCCAGATCAACACCACTGG	RNF43	ENSG00000108375	0.3574024890665489	[3]	[3,3,0,0]	2	hSpCas9	positive selection	4230997
58362570	58362593	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.20093666558091003	[2]	[2,1]	4	hSpCas9	positive selection	4295316
58362588	58362611	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.2042435298757057	[3]	[3,2]	4	hSpCas9	positive selection	4295317
58363264	58363287	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	0.2599151601165157	[2]	[2,2]	5	hSpCas9	positive selection	4295318
58360918	58360941	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.12484048566674164	[2]	[2,1]	2	hSpCas9	positive selection	4359570
58363289	58363312	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.09922171439096666	[3]	[3,1]	2	hSpCas9	positive selection	4359571
58360803	58360826	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.11323191499704399	[4]	[4,3]	2	hSpCas9	positive selection	4359572
58358780	58358802	17	+	27760321	OCIAML3	viability	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	0.016297519920889403	[547,488]	[399,421]	0	hSpCas9	negative selection	4435341
58360179	58360201	17	+	27760321	OCIAML3	viability	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.639071453502201	[349,305]	[395,401]	7	hSpCas9	negative selection	4435342
58360198	58360220	17	+	27760321	OCIAML3	viability	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.5906957488236658	[412,333]	[417,462]	7	hSpCas9	negative selection	4435343
58370944	58370966	17	-	27760321	OCIAML3	viability	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	0.8706728935081107	[651,567]	[792,970]	8	hSpCas9	negative selection	4435344
58370987	58371009	17	+	27760321	OCIAML3	viability	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	0.12658741539712876	[613,470]	[325,633]	1	hSpCas9	negative selection	4435345
58358780	58358802	17	+	27760321	OCIAML2	viability	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	0.11389501655889944	[547,488]	[454,450]	1	hSpCas9	negative selection	4518804
58360179	58360201	17	+	27760321	OCIAML2	viability	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.023085222649078807	[349,305]	[265,272]	0	hSpCas9	negative selection	4518805
58360198	58360220	17	+	27760321	OCIAML2	viability	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.059137344093673244	[412,333]	[278,357]	0	hSpCas9	negative selection	4518806
58370944	58370966	17	-	27760321	OCIAML2	viability	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	0.39741981167305723	[651,567]	[647,648]	5	hSpCas9	negative selection	4518807
58370987	58371009	17	+	27760321	OCIAML2	viability	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	0.2801278781350096	[613,470]	[439,645]	4	hSpCas9	negative selection	4518808
58358780	58358802	17	+	27760321	MV411	viability	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	-0.14765334883221387	[547,488]	[361,227]	-1	hSpCas9	negative selection	4602267
58360179	58360201	17	+	27760321	MV411	viability	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.5606315654907388	[349,305]	[236,440]	4	hSpCas9	negative selection	4602268
58360198	58360220	17	+	27760321	MV411	viability	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	1.0917562988087046	[412,333]	[619,375]	7	hSpCas9	negative selection	4602269
58370944	58370966	17	-	27760321	MV411	viability	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	0.2592914061508433	[651,567]	[546,380]	1	hSpCas9	negative selection	4602270
58370987	58371009	17	+	27760321	MV411	viability	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	0.5332566180497846	[613,470]	[255,901]	4	hSpCas9	negative selection	4602271
58358780	58358802	17	+	27760321	HL60	viability	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	-0.5030560424160029	[547,488]	[362,229]	-5	hSpCas9	negative selection	4685730
58360179	58360201	17	+	27760321	HL60	viability	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.07012910528635108	[349,305]	[202,362]	0	hSpCas9	negative selection	4685731
58360198	58360220	17	+	27760321	HL60	viability	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.5321648266707162	[412,333]	[399,479]	6	hSpCas9	negative selection	4685732
58370944	58370966	17	-	27760321	HL60	viability	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	0.5182965698808295	[651,567]	[827,588]	6	hSpCas9	negative selection	4685733
58370987	58371009	17	+	27760321	HL60	viability	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	0.614142798376343	[613,470]	[563,788]	7	hSpCas9	negative selection	4685734
58358780	58358802	17	+	27760321	HT1080	viability	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	-0.5216355579044045	[488,381]	[159,77]	-2	hSpCas9	negative selection	4769193
58360179	58360201	17	+	27760321	HT1080	viability	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.8163558975000983	[305,238]	[257,117]	4	hSpCas9	negative selection	4769194
58360198	58360220	17	+	27760321	HT1080	viability	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	-0.5676148047367005	[333,260]	[110,45]	-3	hSpCas9	negative selection	4769195
58370944	58370966	17	-	27760321	HT1080	viability	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	-0.1745144488792002	[567,442]	[218,133]	-1	hSpCas9	negative selection	4769196
58370987	58371009	17	+	27760321	HT1080	viability	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	0.7602770123417145	[470,367]	[189,384]	4	hSpCas9	negative selection	4769197
58358780	58358802	17	+	27760321	HT29	viability after 7 days	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	0.062496830091064215	[488,381]	[688,644,438]	0	hSpCas9	negative selection	4852656
58360179	58360201	17	+	27760321	HT29	viability after 7 days	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.3582829123556783	[305,238]	[431,547,366]	5	hSpCas9	negative selection	4852657
58360198	58360220	17	+	27760321	HT29	viability after 7 days	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	-0.11176401234420075	[333,260]	[396,263,404]	-2	hSpCas9	negative selection	4852658
58370944	58370966	17	-	27760321	HT29	viability after 7 days	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	0.26527894018531034	[567,442]	[948,950,475]	4	hSpCas9	negative selection	4852659
58370987	58371009	17	+	27760321	HT29	viability after 7 days	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	-0.4608887528221791	[470,367]	[686,227,304]	-6	hSpCas9	negative selection	4852660
58358780	58358802	17	+	27760321	HT29	viability after 25 days	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	-0.036172357000737176	[488,381]	[614,340,491]	0	hSpCas9	negative selection	4936119
58360179	58360201	17	+	27760321	HT29	viability after 25 days	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.8235776238776666	[305,238]	[547,500,609]	8	hSpCas9	negative selection	4936120
58360198	58360220	17	+	27760321	HT29	viability after 25 days	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.3790727805337631	[333,260]	[441,509,365]	4	hSpCas9	negative selection	4936121
58370944	58370966	17	-	27760321	HT29	viability after 25 days	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	0.5738041638774671	[567,442]	[688,944,965]	6	hSpCas9	negative selection	4936122
58370987	58371009	17	+	27760321	HT29	viability after 25 days	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	0.33153393688987565	[470,367]	[573,709,517]	3	hSpCas9	negative selection	4936123
58358780	58358802	17	+	27760321	HT29	viability after 22 days	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	0.16806684046809306	[488,381]	[793,528,365]	1	hSpCas9	negative selection	5019582
58360179	58360201	17	+	27760321	HT29	viability after 22 days	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.6844019483540145	[305,238]	[568,453,493]	7	hSpCas9	negative selection	5019583
58360198	58360220	17	+	27760321	HT29	viability after 22 days	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.6349491478891247	[333,260]	[515,637,447]	7	hSpCas9	negative selection	5019584
58370944	58370966	17	-	27760321	HT29	viability after 22 days	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	0.6519032033024132	[567,442]	[734,1044,979]	7	hSpCas9	negative selection	5019585
58370987	58371009	17	+	27760321	HT29	viability after 22 days	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	0.5290374456396314	[470,367]	[833,649,610]	6	hSpCas9	negative selection	5019586
58358780	58358802	17	+	27760321	HT29	viability after 19 days	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	-0.3297524864646949	[488,381]	[562,349,296]	-3	hSpCas9	negative selection	5103045
58360179	58360201	17	+	27760321	HT29	viability after 19 days	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.6988811088584019	[305,238]	[434,569,504]	7	hSpCas9	negative selection	5103046
58360198	58360220	17	+	27760321	HT29	viability after 19 days	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.46192026313996976	[333,260]	[527,711,182]	4	hSpCas9	negative selection	5103047
58370944	58370966	17	-	27760321	HT29	viability after 19 days	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	0.7344720292780116	[567,442]	[993,523,1354]	7	hSpCas9	negative selection	5103048
58370987	58371009	17	+	27760321	HT29	viability after 19 days	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	0.08483180408385013	[470,367]	[614,269,646]	0	hSpCas9	negative selection	5103049
58358780	58358802	17	+	27760321	HT29	viability after 16 days	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	-0.03664805466414775	[488,381]	[722,416,309]	0	hSpCas9	negative selection	5186508
58360179	58360201	17	+	27760321	HT29	viability after 16 days	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.9119750909810378	[305,238]	[601,597,522]	9	hSpCas9	negative selection	5186509
58360198	58360220	17	+	27760321	HT29	viability after 16 days	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.7575475180771002	[333,260]	[632,363,702]	8	hSpCas9	negative selection	5186510
58370944	58370966	17	-	27760321	HT29	viability after 16 days	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	0.7008800758894147	[567,442]	[932,955,868]	7	hSpCas9	negative selection	5186511
58370987	58371009	17	+	27760321	HT29	viability after 16 days	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	0.310365316125665	[470,367]	[893,484,398]	3	hSpCas9	negative selection	5186512
58358780	58358802	17	+	27760321	HT29	viability after 13 days	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	0.2909985618469013	[488,381]	[861,546,454]	3	hSpCas9	negative selection	5269971
58360179	58360201	17	+	27760321	HT29	viability after 13 days	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.7385095978520253	[305,238]	[593,423,561]	8	hSpCas9	negative selection	5269972
58360198	58360220	17	+	27760321	HT29	viability after 13 days	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.15450176855333636	[333,260]	[343,363,440]	2	hSpCas9	negative selection	5269973
58370944	58370966	17	-	27760321	HT29	viability after 13 days	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	0.5175050896360041	[567,442]	[619,979,913]	6	hSpCas9	negative selection	5269974
58370987	58371009	17	+	27760321	HT29	viability after 13 days	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	0.19956213875062237	[470,367]	[543,528,600]	2	hSpCas9	negative selection	5269975
58358780	58358802	17	+	27760321	HT29	viability after 10 days	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	0.29330501589150093	[488,381]	[612,529,847]	4	hSpCas9	negative selection	5353434
58360179	58360201	17	+	27760321	HT29	viability after 10 days	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.7799542243055253	[305,238]	[814,428,505]	9	hSpCas9	negative selection	5353435
58360198	58360220	17	+	27760321	HT29	viability after 10 days	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.4042698054228543	[333,260]	[565,442,464]	5	hSpCas9	negative selection	5353436
58370944	58370966	17	-	27760321	HT29	viability after 10 days	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	0.20641816417965403	[567,442]	[749,688,743]	2	hSpCas9	negative selection	5353437
58370987	58371009	17	+	27760321	HT29	viability after 10 days	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	-0.046715132643823015	[470,367]	[532,349,630]	0	hSpCas9	negative selection	5353438
58358780	58358802	17	+	27760321	MOLM13	viability	GTAAGATCGAGAGGGTCCCAGG	RNF43	ENSG00000108375	0.06667828609414106	[547,488]	[346,270]	0	hSpCas9	negative selection	5436897
58360179	58360201	17	+	27760321	MOLM13	viability	TCCGATGCTGATGTAACCAGGG	RNF43	ENSG00000108375	0.43958490130632705	[349,305]	[190,300]	3	hSpCas9	negative selection	5436898
58360198	58360220	17	+	27760321	MOLM13	viability	GGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.9002181699660944	[412,333]	[435,352]	6	hSpCas9	negative selection	5436899
58370944	58370966	17	-	27760321	MOLM13	viability	CAAGCTGGAGAGTCCTCGACGG	RNF43	ENSG00000108375	0.10306398475163087	[651,567]	[270,451]	0	hSpCas9	negative selection	5436900
58370987	58371009	17	+	27760321	MOLM13	viability	TCCAGATTGTCGTCATCACTGG	RNF43	ENSG00000108375	0.202399178765651	[613,470]	[550,177]	1	hSpCas9	negative selection	5436901
58417027	58417050	17	+	27661255	K562	viability	GTCGGGCCCACTGGAATCCACGG	RNF43	ENSG00000108375	0.15327212820474123	[1357,1510]	[1462,1108]	5	dCas9-KRAB	negative selection	5508060
58417030	58417053	17	+	27661255	K562	viability	GGGCCCACTGGAATCCACGGGGG	RNF43	ENSG00000108375	-0.03805095468580491	[827,942]	[743,638]	-1	dCas9-KRAB	negative selection	5508061
58417134	58417157	17	-	27661255	K562	viability	GGTTTGGTTGCAGAGTAAGAAGG	RNF43	ENSG00000108375	0.1094018688956031	[2221,2560]	[2304,1842]	4	dCas9-KRAB	negative selection	5508062
58417585	58417608	17	-	27661255	K562	viability	GAGCGTGATTGCAGTCCCAGGGG	RNF43	ENSG00000108375	0.06335661391519082	[1029,975]	[905,779]	2	dCas9-KRAB	negative selection	5508063
58362570	58362593	17	+	27260156	BXPC3	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.518692867357989	[274]	[451,268,458,477]	9	hSpCas9	negative selection	5567776
58362588	58362611	17	-	27260156	BXPC3	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.32314237919431765	[795]	[972,947,1116,1146]	7	hSpCas9	negative selection	5567777
58363264	58363287	17	+	27260156	BXPC3	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.22685069198613883	[312]	[202,292,262,376]	-5	hSpCas9	negative selection	5567778
58360918	58360941	17	-	27260156	BXPC3	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.11345053711704267	[245]	[227,214,216,298]	-3	hSpCas9	negative selection	5632030
58363289	58363312	17	-	27260156	BXPC3	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.3991485850987603	[526]	[671,658,853,728]	8	hSpCas9	negative selection	5632031
58360803	58360826	17	-	27260156	BXPC3	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	-0.07665790583087562	[1553]	[1360,1460,1475,1924]	-2	hSpCas9	negative selection	5632032
58362570	58362593	17	+	27260156	A673	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.517306007377685	[274]	[445,498,420,522]	9	hSpCas9	negative selection	5689027
58362588	58362611	17	-	27260156	A673	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.29181618016948996	[795]	[1272,1043,1069,1314]	6	hSpCas9	negative selection	5689028
58363264	58363287	17	+	27260156	A673	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	0.22614919752506013	[312]	[514,414,430,403]	5	hSpCas9	negative selection	5689029
58360918	58360941	17	-	27260156	A673	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.20930617797184614	[245]	[285,244,302,186]	-5	hSpCas9	negative selection	5753281
58363289	58363312	17	-	27260156	A673	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.24004991253680605	[526]	[838,724,710,722]	5	hSpCas9	negative selection	5753282
58360803	58360826	17	-	27260156	A673	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.0786800043853284	[1553]	[2138,1773,1949,2043]	2	hSpCas9	negative selection	5753283
58362570	58362593	17	+	27260156	A375	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.7211415433739025	[274]	[473,556,555,531]	9	hSpCas9	negative selection	5810278
58362588	58362611	17	-	27260156	A375	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.6015451615398172	[795]	[1230,1374,1373,1624]	8	hSpCas9	negative selection	5810279
58363264	58363287	17	+	27260156	A375	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.5179941000549076	[312]	[168,246,333,266]	-6	hSpCas9	negative selection	5810280
58360918	58360941	17	-	27260156	A375	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.2023231928122432	[245]	[308,558,295,203]	3	hSpCas9	negative selection	5874532
58363289	58363312	17	-	27260156	A375	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.5741965517735995	[526]	[877,1077,928,811]	8	hSpCas9	negative selection	5874533
58360803	58360826	17	-	27260156	A375	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.1893066534929717	[1553]	[1914,2493,1599,2291]	2	hSpCas9	negative selection	5874534
58362570	58362593	17	+	27260156	COLO741	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.9143087385048378	[274]	[551,816,610]	9	hSpCas9	negative selection	5931529
58362588	58362611	17	-	27260156	COLO741	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.43147411820259507	[795]	[1434,1407,1280]	8	hSpCas9	negative selection	5931530
58363264	58363287	17	+	27260156	COLO741	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	0.14338251099154198	[312]	[698,379,278]	3	hSpCas9	negative selection	5931531
58360918	58360941	17	-	27260156	COLO741	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.17539057517173795	[245]	[266,437,351]	4	hSpCas9	negative selection	5995783
58363289	58363312	17	-	27260156	COLO741	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.28334498387258633	[526]	[983,858,640]	6	hSpCas9	negative selection	5995784
58360803	58360826	17	-	27260156	COLO741	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.031686417161332914	[1553]	[2047,2134,1911]	0	hSpCas9	negative selection	5995785
58362570	58362593	17	+	27260156	CAL120	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.5721758064829009	[274]	[553,417,559]	8	hSpCas9	negative selection	6052780
58362588	58362611	17	-	27260156	CAL120	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.6890666700345155	[795]	[1857,1120,1845]	8	hSpCas9	negative selection	6052781
58363264	58363287	17	+	27260156	CAL120	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	0.049916637856199264	[312]	[285,512,392]	0	hSpCas9	negative selection	6052782
58360918	58360941	17	-	27260156	CAL120	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.09475138955939766	[245]	[243,297,310]	-1	hSpCas9	negative selection	6117034
58363289	58363312	17	-	27260156	CAL120	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.373596165361612	[526]	[910,809,836]	5	hSpCas9	negative selection	6117035
58360803	58360826	17	-	27260156	CAL120	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.08580713442020027	[1553]	[1775,2485,1855]	1	hSpCas9	negative selection	6117036
58362570	58362593	17	+	27260156	CADOES1	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.498446054202181	[274]	[354,421,317,349]	7	hSpCas9	negative selection	6174031
58362588	58362611	17	-	27260156	CADOES1	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.5036856983945214	[795]	[1566,785,967,868]	8	hSpCas9	negative selection	6174032
58363264	58363287	17	+	27260156	CADOES1	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.28323041424476236	[312]	[311,175,268,197]	-5	hSpCas9	negative selection	6174033
58360918	58360941	17	-	27260156	CADOES1	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.24485086485181995	[245]	[356,232,150,345]	4	hSpCas9	negative selection	6238285
58363289	58363312	17	-	27260156	CADOES1	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.03850797798537531	[526]	[617,438,431,524]	0	hSpCas9	negative selection	6238286
58360803	58360826	17	-	27260156	CADOES1	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.28180902393945373	[1553]	[1761,2100,1539,1620]	5	hSpCas9	negative selection	6238287
58362570	58362593	17	+	27260156	EWS502	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.4979613186370716	[274]	[355,445,506,335]	8	hSpCas9	negative selection	6295282
58362588	58362611	17	-	27260156	EWS502	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.593673057874624	[795]	[1148,1247,1312,1399]	8	hSpCas9	negative selection	6295283
58363264	58363287	17	+	27260156	EWS502	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.10782125699350653	[312]	[237,339,401,253]	-2	hSpCas9	negative selection	6295284
58360918	58360941	17	-	27260156	EWS502	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.0008539958728529529	[245]	[139,354,245,313]	0	hSpCas9	negative selection	6359536
58363289	58363312	17	-	27260156	EWS502	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.08656235503657936	[526]	[464,722,497,698]	1	hSpCas9	negative selection	6359537
58360803	58360826	17	-	27260156	EWS502	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.27242783564549833	[1553]	[2081,1745,1693,2449]	5	hSpCas9	negative selection	6359538
58362570	58362593	17	+	27260156	EW8	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.5243395167564819	[274]	[295,271,338,367]	8	hSpCas9	negative selection	6416533
58362588	58362611	17	-	27260156	EW8	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.24967482033549027	[795]	[926,803,742,613]	4	hSpCas9	negative selection	6416534
58363264	58363287	17	+	27260156	EW8	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	0.023889895628676494	[312]	[385,200,232,228]	0	hSpCas9	negative selection	6416535
58360918	58360941	17	-	27260156	EW8	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.01412534171123514	[245]	[183,161,245,202]	0	hSpCas9	negative selection	6480787
58363289	58363312	17	-	27260156	EW8	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.22831326191196885	[526]	[658,398,493,465]	4	hSpCas9	negative selection	6480788
58360803	58360826	17	-	27260156	EW8	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.13333926965395482	[1553]	[1507,1319,1237,1492]	2	hSpCas9	negative selection	6480789
58362570	58362593	17	+	27260156	CORL105	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.4719501830410447	[274]	[476,431,531,359]	8	hSpCas9	negative selection	6537784
58362588	58362611	17	-	27260156	CORL105	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.31419470403131877	[795]	[1082,1247,1297,1022]	6	hSpCas9	negative selection	6537785
58363264	58363287	17	+	27260156	CORL105	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.6667990849392057	[312]	[217,200,204,294]	-8	hSpCas9	negative selection	6537786
58360918	58360941	17	-	27260156	CORL105	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.35891229461187335	[245]	[505,283,376,317]	6	hSpCas9	negative selection	6602038
58363289	58363312	17	-	27260156	CORL105	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.47757623428051	[526]	[1008,898,808,715]	8	hSpCas9	negative selection	6602039
58360803	58360826	17	-	27260156	CORL105	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.12343393559455773	[1553]	[1797,1856,2455,1885]	2	hSpCas9	negative selection	6602040
58362570	58362593	17	+	27260156	HS294T	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.6374059091152604	[274]	[137,154,185,188]	8	hSpCas9	negative selection	6659035
58362588	58362611	17	-	27260156	HS294T	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.9360177096758443	[795]	[769,571,426,562]	9	hSpCas9	negative selection	6659036
58363264	58363287	17	+	27260156	HS294T	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.6064551682824041	[312]	[69,60,99,89]	-7	hSpCas9	negative selection	6659037
58360918	58360941	17	-	27260156	HS294T	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.10679382264704396	[245]	[143,40,66,98]	-1	hSpCas9	negative selection	6723289
58363289	58363312	17	-	27260156	HS294T	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.333272304797241	[526]	[160,383,218,268]	4	hSpCas9	negative selection	6723290
58360803	58360826	17	-	27260156	HS294T	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.6238170255099533	[1553]	[671,675,808,1706]	7	hSpCas9	negative selection	6723291
58362570	58362593	17	+	27260156	HCC44	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.7485149629888715	[274]	[353,596,553,558]	9	hSpCas9	negative selection	6780286
58362588	58362611	17	-	27260156	HCC44	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.464644010233365	[795]	[1424,811,1487,1350]	7	hSpCas9	negative selection	6780287
58363264	58363287	17	+	27260156	HCC44	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	0.3016994496821116	[312]	[372,457,516,399]	5	hSpCas9	negative selection	6780288
58360918	58360941	17	-	27260156	HCC44	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.13033283751110813	[245]	[250,216,312,248]	-2	hSpCas9	negative selection	6844540
58363289	58363312	17	-	27260156	HCC44	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.6555623189649675	[526]	[1340,937,849,649]	9	hSpCas9	negative selection	6844541
58360803	58360826	17	-	27260156	HCC44	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.011759226998717454	[1553]	[1494,1536,2363,1786]	0	hSpCas9	negative selection	6844542
58362570	58362593	17	+	27260156	G402	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.7385778232282751	[274]	[959,354,466,503]	8	hSpCas9	negative selection	6901537
58362588	58362611	17	-	27260156	G402	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.48067732751396386	[795]	[1174,1628,1693,928]	6	hSpCas9	negative selection	6901538
58363264	58363287	17	+	27260156	G402	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.2615409433708198	[312]	[395,203,365,311]	-3	hSpCas9	negative selection	6901539
58360918	58360941	17	-	27260156	G402	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.4620598676542489	[245]	[288,165,267,157]	-5	hSpCas9	negative selection	6965791
58363289	58363312	17	-	27260156	G402	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.29533611841385154	[526]	[1074,811,539,769]	3	hSpCas9	negative selection	6965792
58360803	58360826	17	-	27260156	G402	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.2823363151089333	[1553]	[1889,2309,2744,2214]	3	hSpCas9	negative selection	6965793
58362570	58362593	17	+	27260156	L33	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.1828395267279026	[274]	[328,138,166,313]	4	hSpCas9	negative selection	7022788
58362588	58362611	17	-	27260156	L33	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.29534240534116873	[795]	[966,413,619,943]	6	hSpCas9	negative selection	7022789
58363264	58363287	17	+	27260156	L33	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.16014653079981567	[312]	[371,107,128,276]	-4	hSpCas9	negative selection	7022790
58360918	58360941	17	-	27260156	L33	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.1583862472692833	[245]	[314,108,102,350]	3	hSpCas9	negative selection	7087042
58363289	58363312	17	-	27260156	L33	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.2680751116150013	[526]	[583,230,433,700]	6	hSpCas9	negative selection	7087043
58360803	58360826	17	-	27260156	L33	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.001045209378081724	[1553]	[1507,606,1151,1401]	0	hSpCas9	negative selection	7087044
58362570	58362593	17	+	27260156	K562	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.9769467796024388	[274]	[548,521,298,548]	9	hSpCas9	negative selection	7144039
58362588	58362611	17	-	27260156	K562	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.3607387658590321	[795]	[1238,1171,757,539]	4	hSpCas9	negative selection	7144040
58363264	58363287	17	+	27260156	K562	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.38221665464538157	[312]	[189,255,136,262]	-5	hSpCas9	negative selection	7144041
58360918	58360941	17	-	27260156	K562	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.266646245303813	[245]	[193,180,130,215]	-3	hSpCas9	negative selection	7208293
58363289	58363312	17	-	27260156	K562	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.39609439431888016	[526]	[705,703,547,523]	5	hSpCas9	negative selection	7208294
58360803	58360826	17	-	27260156	K562	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.23472425352930681	[1553]	[1344,1486,1894,1715]	3	hSpCas9	negative selection	7208295
58362570	58362593	17	+	27260156	HT29	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.5297440342117272	[274]	[641,516,460,339]	8	hSpCas9	negative selection	7265290
58362588	58362611	17	-	27260156	HT29	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.3869927445441056	[795]	[1300,1408,1251,1122]	7	hSpCas9	negative selection	7265291
58363264	58363287	17	+	27260156	HT29	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	0.1861557063078635	[312]	[498,483,394,367]	3	hSpCas9	negative selection	7265292
58360918	58360941	17	-	27260156	HT29	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.11033152212880548	[245]	[367,311,257,349]	2	hSpCas9	negative selection	7329544
58363289	58363312	17	-	27260156	HT29	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.21114705922087137	[526]	[817,567,788,772]	4	hSpCas9	negative selection	7329545
58360803	58360826	17	-	27260156	HT29	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.23899851261155214	[1553]	[2586,2004,2324,2018]	4	hSpCas9	negative selection	7329546
58362570	58362593	17	+	27260156	MHHES1	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.4290755571982025	[274]	[387,548,467,292]	7	hSpCas9	negative selection	7386541
58362588	58362611	17	-	27260156	MHHES1	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.40871754745403066	[795]	[1329,1135,1130,1154]	7	hSpCas9	negative selection	7386542
58363264	58363287	17	+	27260156	MHHES1	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.2959921203979907	[312]	[384,183,361,226]	-5	hSpCas9	negative selection	7386543
58360918	58360941	17	-	27260156	MHHES1	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.001701372671218393	[245]	[477,246,220,196]	0	hSpCas9	negative selection	7450795
58363289	58363312	17	-	27260156	MHHES1	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.5313007416446922	[526]	[1017,692,987,742]	8	hSpCas9	negative selection	7450796
58360803	58360826	17	-	27260156	MHHES1	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	-0.07684945147769828	[1553]	[2307,1905,1638,1004]	-1	hSpCas9	negative selection	7450797
58362570	58362593	17	+	27260156	MEWO	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.26795946900453504	[274]	[413,205,329]	6	hSpCas9	negative selection	7507792
58362588	58362611	17	-	27260156	MEWO	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.4509404748090252	[795]	[1223,1136,731]	8	hSpCas9	negative selection	7507793
58363264	58363287	17	+	27260156	MEWO	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.2846448979485937	[312]	[296,261,172]	-6	hSpCas9	negative selection	7507794
58360918	58360941	17	-	27260156	MEWO	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.08035444668473635	[245]	[325,212,134]	-2	hSpCas9	negative selection	7572046
58363289	58363312	17	-	27260156	MEWO	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.1771717249448365	[526]	[546,606,515]	4	hSpCas9	negative selection	7572047
58360803	58360826	17	-	27260156	MEWO	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.01624781158099542	[1553]	[1887,1383,1219]	0	hSpCas9	negative selection	7572048
58362570	58362593	17	+	27260156	LNCAPCLONEFGC	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.9242463251305306	[274]	[458,397,574,478]	9	hSpCas9	negative selection	7629043
58362588	58362611	17	-	27260156	LNCAPCLONEFGC	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.679481697575495	[795]	[1047,1100,1355,1148]	9	hSpCas9	negative selection	7629044
58363264	58363287	17	+	27260156	LNCAPCLONEFGC	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.49320634295378085	[312]	[217,150,230,212]	-6	hSpCas9	negative selection	7629045
58360918	58360941	17	-	27260156	LNCAPCLONEFGC	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.13442128804466547	[245]	[220,217,254,287]	2	hSpCas9	negative selection	7693297
58363289	58363312	17	-	27260156	LNCAPCLONEFGC	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.32151201257347695	[526]	[596,505,799,518]	5	hSpCas9	negative selection	7693298
58360803	58360826	17	-	27260156	LNCAPCLONEFGC	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.3608361139044114	[1553]	[1652,1550,2483,1661]	5	hSpCas9	negative selection	7693299
58362570	58362593	17	+	27260156	PANC0327	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.6779678012137048	[274]	[307,350,618,283]	8	hSpCas9	negative selection	7750294
58362588	58362611	17	-	27260156	PANC0327	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.3633436160622142	[795]	[938,856,1190,660]	5	hSpCas9	negative selection	7750295
58363264	58363287	17	+	27260156	PANC0327	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.16941468836805973	[312]	[274,249,330,134]	-3	hSpCas9	negative selection	7750296
58360918	58360941	17	-	27260156	PANC0327	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.6181633627860819	[245]	[193,301,262,574]	8	hSpCas9	negative selection	7814548
58363289	58363312	17	-	27260156	PANC0327	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.32791460848653575	[526]	[765,678,479,427]	5	hSpCas9	negative selection	7814549
58360803	58360826	17	-	27260156	PANC0327	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.4490998711511074	[1553]	[2712,1482,1632,1827]	6	hSpCas9	negative selection	7814550
58362570	58362593	17	+	27260156	NCIH2009	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.7937129643430734	[274]	[699,816,483]	9	hSpCas9	negative selection	7871545
58362588	58362611	17	-	27260156	NCIH2009	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.48161596609745605	[795]	[1786,1623,1289]	6	hSpCas9	negative selection	7871546
58363264	58363287	17	+	27260156	NCIH2009	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.608028629319424	[312]	[396,287,196]	-6	hSpCas9	negative selection	7871547
58360918	58360941	17	-	27260156	NCIH2009	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.801982687429118	[245]	[290,120,198]	-7	hSpCas9	negative selection	7935799
58363289	58363312	17	-	27260156	NCIH2009	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.03520420028250748	[526]	[966,709,627]	0	hSpCas9	negative selection	7935800
58360803	58360826	17	-	27260156	NCIH2009	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.17194274680467303	[1553]	[2690,2019,2678]	2	hSpCas9	negative selection	7935801
58362570	58362593	17	+	27260156	NCIH1373	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	1.151759058723107	[274]	[859,385,930,159]	9	hSpCas9	negative selection	7992796
58362588	58362611	17	-	27260156	NCIH1373	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.8284786680566328	[795]	[1483,1566,1503,465]	8	hSpCas9	negative selection	7992797
58363264	58363287	17	+	27260156	NCIH1373	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.617524904186402	[312]	[137,191,226,92]	-6	hSpCas9	negative selection	7992798
58360918	58360941	17	-	27260156	NCIH1373	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.17239251237971343	[245]	[411,178,222,50]	-2	hSpCas9	negative selection	8057050
58363289	58363312	17	-	27260156	NCIH1373	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	-0.051832022134445876	[526]	[1030,305,579,118]	0	hSpCas9	negative selection	8057051
58360803	58360826	17	-	27260156	NCIH1373	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.47332618172464946	[1553]	[2306,2335,2356,700]	4	hSpCas9	negative selection	8057052
58362570	58362593	17	+	27260156	PATU8902	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	1.5837741354244992	[274]	[829,865,1024,1998]	9	hSpCas9	negative selection	8114047
58362588	58362611	17	-	27260156	PATU8902	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.3560338828379016	[795]	[1241,1147,1490,1812]	3	hSpCas9	negative selection	8114048
58363264	58363287	17	+	27260156	PATU8902	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-1.2814273001351122	[312]	[213,202,26,328]	-8	hSpCas9	negative selection	8114049
58360918	58360941	17	-	27260156	PATU8902	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-1.0789697324418501	[245]	[193,104,131,231]	-7	hSpCas9	negative selection	8178301
58363289	58363312	17	-	27260156	PATU8902	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	-0.11556402416878025	[526]	[560,737,547,921]	-1	hSpCas9	negative selection	8178302
58360803	58360826	17	-	27260156	PATU8902	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.3600175277164157	[1553]	[2962,3616,1859,2901]	3	hSpCas9	negative selection	8178303
58362570	58362593	17	+	27260156	PANC1	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.3265805004352054	[274]	[265,347,412,183]	5	hSpCas9	negative selection	8235298
58362588	58362611	17	-	27260156	PANC1	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.5337910532584212	[795]	[840,1342,1020,838]	8	hSpCas9	negative selection	8235299
58363264	58363287	17	+	27260156	PANC1	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.05663994882857948	[312]	[257,279,211,279]	-1	hSpCas9	negative selection	8235300
58360918	58360941	17	-	27260156	PANC1	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.03824534549297487	[245]	[172,352,277,107]	0	hSpCas9	negative selection	8299552
58363289	58363312	17	-	27260156	PANC1	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.36179892634592337	[526]	[544,692,493,603]	6	hSpCas9	negative selection	8299553
58360803	58360826	17	-	27260156	PANC1	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.234510216640766	[1553]	[1607,1969,1561,1249]	4	hSpCas9	negative selection	8299554
58362570	58362593	17	+	27260156	PANC0813	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.49871502940641055	[274]	[446,429,623,330]	7	hSpCas9	negative selection	8356549
58362588	58362611	17	-	27260156	PANC0813	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.5096044773869707	[795]	[1197,1536,1234,1338]	7	hSpCas9	negative selection	8356550
58363264	58363287	17	+	27260156	PANC0813	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.24201956612339626	[312]	[233,301,435,266]	-4	hSpCas9	negative selection	8356551
58360918	58360941	17	-	27260156	PANC0813	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.1290171599188329	[245]	[217,418,193,416]	2	hSpCas9	negative selection	8420803
58363289	58363312	17	-	27260156	PANC0813	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.22895768711159512	[526]	[606,846,886,558]	3	hSpCas9	negative selection	8420804
58360803	58360826	17	-	27260156	PANC0813	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	-0.07593999958087139	[1553]	[1886,1641,1858,1560]	-1	hSpCas9	negative selection	8420805
58362570	58362593	17	+	27260156	RDES	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.6926332605313458	[274]	[460,436,555,608]	9	hSpCas9	negative selection	8477800
58362588	58362611	17	-	27260156	RDES	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.49043470350703566	[795]	[1137,1137,1288,1638]	7	hSpCas9	negative selection	8477801
58363264	58363287	17	+	27260156	RDES	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.24571588661310306	[312]	[183,268,366,438]	-4	hSpCas9	negative selection	8477802
58360918	58360941	17	-	27260156	RDES	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.08554683796554707	[245]	[305,265,261,203]	-1	hSpCas9	negative selection	8542054
58363289	58363312	17	-	27260156	RDES	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.09245853033667509	[526]	[487,688,632,809]	1	hSpCas9	negative selection	8542055
58360803	58360826	17	-	27260156	RDES	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	-0.026027684203016044	[1553]	[1392,1744,1746,2234]	0	hSpCas9	negative selection	8542056
58362570	58362593	17	+	27260156	PC3	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.4312463413915963	[274]	[231,302,756,365]	8	hSpCas9	negative selection	8599051
58362588	58362611	17	-	27260156	PC3	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.29873060807118945	[795]	[628,915,1511,1119]	6	hSpCas9	negative selection	8599052
58363264	58363287	17	+	27260156	PC3	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	0.0374999656017061	[312]	[175,255,574,416]	0	hSpCas9	negative selection	8599053
58360918	58360941	17	-	27260156	PC3	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.2658917960688614	[245]	[164,214,295,164]	-6	hSpCas9	negative selection	8663305
58363289	58363312	17	-	27260156	PC3	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.4031763597403467	[526]	[582,584,1057,659]	8	hSpCas9	negative selection	8663306
58360803	58360826	17	-	27260156	PC3	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.1048952861549064	[1553]	[1015,1463,2810,1970]	2	hSpCas9	negative selection	8663307
58362570	58362593	17	+	27260156	PATU8988T	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.31204849332846435	[274]	[332,268,313,403]	5	hSpCas9	negative selection	8720302
58362588	58362611	17	-	27260156	PATU8988T	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.49665400714065167	[795]	[770,1449,972,1190]	8	hSpCas9	negative selection	8720303
58363264	58363287	17	+	27260156	PATU8988T	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	0.22780442326117384	[312]	[253,342,424,395]	4	hSpCas9	negative selection	8720304
58360918	58360941	17	-	27260156	PATU8988T	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.06727290481683768	[245]	[163,286,269,280]	1	hSpCas9	negative selection	8784556
58363289	58363312	17	-	27260156	PATU8988T	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.31800757487648357	[526]	[362,768,544,896]	5	hSpCas9	negative selection	8784557
58360803	58360826	17	-	27260156	PATU8988T	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.12024363284543771	[1553]	[1218,1694,1594,2059]	2	hSpCas9	negative selection	8784558
58362570	58362593	17	+	27260156	T47D	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.4541546641986629	[274]	[440,358,483,478]	8	hSpCas9	negative selection	8841553
58362588	58362611	17	-	27260156	T47D	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.3845062739263764	[795]	[1208,1155,1159,1325]	7	hSpCas9	negative selection	8841554
58363264	58363287	17	+	27260156	T47D	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.3179111825495953	[312]	[351,272,326,216]	-6	hSpCas9	negative selection	8841555
58360918	58360941	17	-	27260156	T47D	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.1086119868191937	[245]	[357,240,264,380]	2	hSpCas9	negative selection	8905807
58363289	58363312	17	-	27260156	T47D	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.3366946067578702	[526]	[698,764,825,811]	7	hSpCas9	negative selection	8905808
58360803	58360826	17	-	27260156	T47D	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.10246152185949708	[1553]	[1803,1599,1844,2575]	2	hSpCas9	negative selection	8905809
58362570	58362593	17	+	27260156	SU8686	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.41645417375843446	[274]	[358,286,318,522]	7	hSpCas9	negative selection	8962804
58362588	58362611	17	-	27260156	SU8686	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.5495831927406897	[795]	[988,846,1414,1479]	8	hSpCas9	negative selection	8962805
58363264	58363287	17	+	27260156	SU8686	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.5624141901902932	[312]	[192,162,177,331]	-7	hSpCas9	negative selection	8962806
58360918	58360941	17	-	27260156	SU8686	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.023977554058606576	[245]	[237,238,228,253]	0	hSpCas9	negative selection	9027058
58363289	58363312	17	-	27260156	SU8686	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.5368400463853891	[526]	[752,559,833,936]	8	hSpCas9	negative selection	9027059
58360803	58360826	17	-	27260156	SU8686	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.26828899053972566	[1553]	[1570,1659,2061,2241]	4	hSpCas9	negative selection	9027060
58362570	58362593	17	+	27260156	SKES1	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.6075729529178081	[274]	[452,485,451,302]	9	hSpCas9	negative selection	9084055
58362588	58362611	17	-	27260156	SKES1	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.31052181660488964	[795]	[1257,1174,787,793]	6	hSpCas9	negative selection	9084056
58363264	58363287	17	+	27260156	SKES1	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.20155302446756673	[312]	[224,319,321,220]	-4	hSpCas9	negative selection	9084057
58360918	58360941	17	-	27260156	SKES1	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.22439675753607902	[245]	[316,159,155,213]	-5	hSpCas9	negative selection	9148309
58363289	58363312	17	-	27260156	SKES1	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.1808963790934542	[526]	[749,600,586,475]	4	hSpCas9	negative selection	9148310
58360803	58360826	17	-	27260156	SKES1	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.01303756774451803	[1553]	[1613,1980,1351,1375]	0	hSpCas9	negative selection	9148311
58362570	58362593	17	+	27260156	TOV112D	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.6247328822009643	[274]	[352,642,370,379]	9	hSpCas9	negative selection	9205306
58362588	58362611	17	-	27260156	TOV112D	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.5838018715914256	[795]	[1534,1176,1082,1011]	9	hSpCas9	negative selection	9205307
58363264	58363287	17	+	27260156	TOV112D	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.280894204479631	[312]	[360,210,170,284]	-5	hSpCas9	negative selection	9205308
58360918	58360941	17	-	27260156	TOV112D	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.0690123623762422	[245]	[249,317,163,228]	-1	hSpCas9	negative selection	9269560
58363289	58363312	17	-	27260156	TOV112D	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.4162464453853659	[526]	[534,1076,516,762]	7	hSpCas9	negative selection	9269561
58360803	58360826	17	-	27260156	TOV112D	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.12045150456335918	[1553]	[1315,2427,1535,1635]	2	hSpCas9	negative selection	9269562
58362570	58362593	17	+	27260156	TC71	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.24037549722220553	[274]	[394,371,279,346]	6	hSpCas9	negative selection	9326557
58362588	58362611	17	-	27260156	TC71	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.30122045782239437	[795]	[1054,1063,1063,1019]	7	hSpCas9	negative selection	9326558
58363264	58363287	17	+	27260156	TC71	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.010346916851536325	[312]	[312,328,377,309]	0	hSpCas9	negative selection	9326559
58360918	58360941	17	-	27260156	TC71	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	-0.005047167796939256	[245]	[183,366,205,299]	0	hSpCas9	negative selection	9390811
58363289	58363312	17	-	27260156	TC71	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.14950005296426042	[526]	[616,658,626,601]	4	hSpCas9	negative selection	9390812
58360803	58360826	17	-	27260156	TC71	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.011534133649101497	[1553]	[1699,1541,1605,1882]	0	hSpCas9	negative selection	9390813
58362570	58362593	17	+	27260156	TC32	viability	GGATGCGCAGCACCGAAGCCAGG	RNF43	ENSG00000108375	0.5606109191477058	[274]	[350,144,516,622]	8	hSpCas9	negative selection	9447808
58362588	58362611	17	-	27260156	TC32	viability	CACCATCTTTGTGATCATCCTGG	RNF43	ENSG00000108375	0.3764593052226298	[795]	[815,676,1378,1169]	6	hSpCas9	negative selection	9447809
58363264	58363287	17	+	27260156	TC32	viability	AGTGTGCTTACCCAGGCCGGGGG	RNF43	ENSG00000108375	-0.1181432200285546	[312]	[319,177,319,287]	-2	hSpCas9	negative selection	9447810
58360918	58360941	17	-	27260156	TC32	viability	CGCTTCAGCAGAGAACAGCCTGG	RNF43	ENSG00000108375	0.11875038362579804	[245]	[200,219,388,218]	2	hSpCas9	negative selection	9512062
58363289	58363312	17	-	27260156	TC32	viability	CCATGTGAGGATTGAGCTGAAGG	RNF43	ENSG00000108375	0.37984025601012816	[526]	[577,506,886,670]	6	hSpCas9	negative selection	9512063
58360803	58360826	17	-	27260156	TC32	viability	CCCTGTGTGTGCCATCTGTCTGG	RNF43	ENSG00000108375	0.11498013909184168	[1553]	[1797,1039,1826,1797]	2	hSpCas9	negative selection	9512064
58360891	58360914	17	-	27869803	HPAFII	viability after 27 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.49931720011320135	[284]	[147,70,NaN]	-4	hSpCas9	negative selection	9562062
58362586	58362609	17	+	27869803	HPAFII	viability after 27 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	1.0345640373258507	[410]	[482,408,NaN]	8	hSpCas9	negative selection	9562063
58363263	58363286	17	+	27869803	HPAFII	viability after 27 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.3975395680583532	[368]	[188,310,NaN]	3	hSpCas9	negative selection	9562064
58363525	58363548	17	-	27869803	HPAFII	viability after 27 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	-0.5098248579315952	[259]	[35,145,NaN]	-4	hSpCas9	negative selection	9562065
58370997	58371020	17	+	27869803	HPAFII	viability after 27 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.5160084745169979	[566]	[314,518,NaN]	4	hSpCas9	negative selection	9562066
58415469	58415492	17	-	27869803	HPAFII	viability after 27 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.0983679976619316	[203]	[43,146,NaN]	0	hSpCas9	negative selection	9562067
58360891	58360914	17	-	27869803	HPAFII	viability after 15 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	0.038512787692117745	[284]	[329,304,NaN]	0	hSpCas9	negative selection	9644511
58362586	58362609	17	+	27869803	HPAFII	viability after 15 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.3880582395564107	[410]	[828,421,NaN]	4	hSpCas9	negative selection	9644512
58363263	58363286	17	+	27869803	HPAFII	viability after 15 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.5612641060483963	[368]	[808,445,NaN]	6	hSpCas9	negative selection	9644513
58363525	58363548	17	-	27869803	HPAFII	viability after 15 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	-0.22249217955633607	[259]	[183,273,NaN]	-3	hSpCas9	negative selection	9644514
58370997	58371020	17	+	27869803	HPAFII	viability after 15 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.24027733273371132	[566]	[741,705,NaN]	2	hSpCas9	negative selection	9644515
58415469	58415492	17	-	27869803	HPAFII	viability after 15 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.9005770232205774	[203]	[48,159,NaN]	-7	hSpCas9	negative selection	9644516
58360891	58360914	17	-	27869803	ASPC1	viability after 36 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	2.1580318920415813	[722]	[901,527,1746]	9	hSpCas9	negative selection	9726960
58362586	58362609	17	+	27869803	ASPC1	viability after 36 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.45919420120963916	[1069]	[425,372,680]	4	hSpCas9	negative selection	9726961
58363263	58363286	17	+	27869803	ASPC1	viability after 36 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.6099095412741441	[994]	[748,466,420]	6	hSpCas9	negative selection	9726962
58363525	58363548	17	-	27869803	ASPC1	viability after 36 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	0.8625655770488694	[516]	[264,700,72]	8	hSpCas9	negative selection	9726963
58370997	58371020	17	+	27869803	ASPC1	viability after 36 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	3.081783920510329	[1722]	[5973,7602,2426]	9	hSpCas9	negative selection	9726964
58415469	58415492	17	-	27869803	ASPC1	viability after 36 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	2.8317203913393074	[476]	[2380,939,528]	9	hSpCas9	negative selection	9726965
58360891	58360914	17	-	27869803	PATU8988S	viability after 35 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.1863916315321868	[649]	[255,203,NaN]	-2	hSpCas9	negative selection	9809409
58362586	58362609	17	+	27869803	PATU8988S	viability after 35 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.28514611888389374	[975]	[472,484,NaN]	3	hSpCas9	negative selection	9809410
58363263	58363286	17	+	27869803	PATU8988S	viability after 35 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.49871858800246893	[861]	[506,473,NaN]	5	hSpCas9	negative selection	9809411
58363525	58363548	17	-	27869803	PATU8988S	viability after 35 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	-0.9530099677272728	[465]	[73,119,NaN]	-7	hSpCas9	negative selection	9809412
58370997	58371020	17	+	27869803	PATU8988S	viability after 35 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.35916078063770684	[1385]	[718,712,NaN]	4	hSpCas9	negative selection	9809413
58415469	58415492	17	-	27869803	PATU8988S	viability after 35 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	0.14663022854969215	[496]	[256,185,NaN]	1	hSpCas9	negative selection	9809414
58360891	58360914	17	-	27869803	PATU8988S	viability after 31 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.6662333967516922	[649]	[183,136,NaN]	-6	hSpCas9	negative selection	9891858
58362586	58362609	17	+	27869803	PATU8988S	viability after 31 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	0.002204312371277717	[975]	[431,335,NaN]	0	hSpCas9	negative selection	9891859
58363263	58363286	17	+	27869803	PATU8988S	viability after 31 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.6505932787434745	[861]	[400,715,NaN]	7	hSpCas9	negative selection	9891860
58363525	58363548	17	-	27869803	PATU8988S	viability after 31 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	-0.8006613533595921	[465]	[74,146,NaN]	-7	hSpCas9	negative selection	9891861
58370997	58371020	17	+	27869803	PATU8988S	viability after 31 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.3053776682215328	[1385]	[601,785,NaN]	4	hSpCas9	negative selection	9891862
58415469	58415492	17	-	27869803	PATU8988S	viability after 31 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.013306910954276663	[496]	[176,220,NaN]	0	hSpCas9	negative selection	9891863
58360891	58360914	17	-	27869803	HPAFII	viability after 35 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-1.4868381464834919	[284]	[66,33,NaN]	-7	hSpCas9	negative selection	9974307
58362586	58362609	17	+	27869803	HPAFII	viability after 35 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	1.3722512026668834	[410]	[508,571,NaN]	8	hSpCas9	negative selection	9974308
58363263	58363286	17	+	27869803	HPAFII	viability after 35 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.30440911411520843	[368]	[193,271,NaN]	2	hSpCas9	negative selection	9974309
58363525	58363548	17	-	27869803	HPAFII	viability after 35 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	-1.1813154356265425	[259]	[18,101,NaN]	-6	hSpCas9	negative selection	9974310
58370997	58371020	17	+	27869803	HPAFII	viability after 35 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	1.1931134969509012	[566]	[327,1025,NaN]	7	hSpCas9	negative selection	9974311
58415469	58415492	17	-	27869803	HPAFII	viability after 35 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.5291501246102077	[203]	[24,123,NaN]	-3	hSpCas9	negative selection	9974312
58360891	58360914	17	-	27869803	HPAFII	viability after 31 days	TCAGCCAGCTGGCCACCAGGAGG	RNF43	ENSG00000108375	-0.8917114029750264	[284]	[34,141,NaN]	-5	hSpCas9	negative selection	10056756
58362586	58362609	17	+	27869803	HPAFII	viability after 31 days	AGCCAGGATGATCACAAAGATGG	RNF43	ENSG00000108375	1.22045921590659	[410]	[525,549,NaN]	8	hSpCas9	negative selection	10056757
58363263	58363286	17	+	27869803	HPAFII	viability after 31 days	TAGTGTGCTTACCCAGGCCGGGG	RNF43	ENSG00000108375	0.11274297953211754	[368]	[143,310,NaN]	0	hSpCas9	negative selection	10056758
58363525	58363548	17	-	27869803	HPAFII	viability after 31 days	GGATCGAGCTGCTGCTGAGCAGG	RNF43	ENSG00000108375	-1.6018888408004839	[259]	[4,94,NaN]	-7	hSpCas9	negative selection	10056759
58370997	58371020	17	+	27869803	HPAFII	viability after 31 days	CGTCATCACTGGCATTGCACAGG	RNF43	ENSG00000108375	0.8311157945779923	[566]	[456,684,NaN]	6	hSpCas9	negative selection	10056760
58415469	58415492	17	-	27869803	HPAFII	viability after 31 days	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.8017032999419043	[203]	[24,109,NaN]	-5	hSpCas9	negative selection	10056761
58415567	58415590	17	-	28162770	P31FUJ	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-0.16191871825786885	[138]	[145]	-1	hSpCas9	negative selection	10226658
58358155	58358178	17	-	28162770	P31FUJ	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	-0.3234047531952855	[344]	[323]	-3	hSpCas9	negative selection	10226659
58415469	58415492	17	-	28162770	P31FUJ	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	0.7040039690984276	[139]	[267]	7	hSpCas9	negative selection	10226660
58362612	58362635	17	-	28162770	P31FUJ	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	0.47320657720138215	[178]	[291]	5	hSpCas9	negative selection	10226661
58360879	58360902	17	+	28162770	P31FUJ	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	0.03575624789105225	[390]	[470]	0	hSpCas9	negative selection	10226662
58360804	58360827	17	+	28162770	P31FUJ	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	0.32662520419964014	[227]	[335]	3	hSpCas9	negative selection	10226663
58360197	58360220	17	+	28162770	P31FUJ	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.5783409781329333	[162]	[285]	6	hSpCas9	negative selection	10226664
58358737	58358760	17	+	28162770	P31FUJ	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	0.32359114411000656	[16]	[24]	3	hSpCas9	negative selection	10226665
58358701	58358724	17	+	28162770	P31FUJ	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-0.9800361340344121	[93]	[55]	-6	hSpCas9	negative selection	10226666
58358677	58358700	17	-	28162770	P31FUJ	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	-0.3728919763159281	[334]	[303]	-3	hSpCas9	negative selection	10226667
58415567	58415590	17	-	28162770	TF1	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	NaN	[NaN]	[151]	1	hSpCas9	negative selection	10396024
58358155	58358178	17	-	28162770	TF1	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10396025
58415469	58415492	17	-	28162770	TF1	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10396026
58362612	58362635	17	-	28162770	TF1	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10396027
58360879	58360902	17	+	28162770	TF1	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10396028
58360804	58360827	17	+	28162770	TF1	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10396029
58360197	58360220	17	+	28162770	TF1	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	NaN	[NaN]	[110]	1	hSpCas9	negative selection	10396030
58358737	58358760	17	+	28162770	TF1	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10396031
58358701	58358724	17	+	28162770	TF1	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10396032
58358677	58358700	17	-	28162770	TF1	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	NaN	[NaN]	[284]	1	hSpCas9	negative selection	10396033
58415567	58415590	17	-	28162770	SKM1	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-0.448543302494561	[43]	[56]	-4	hSpCas9	negative selection	10565390
58358155	58358178	17	-	28162770	SKM1	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	0.44745897697122117	[55]	[134]	4	hSpCas9	negative selection	10565391
58415469	58415492	17	-	28162770	SKM1	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.735845054272291	[64]	[68]	-5	hSpCas9	negative selection	10565392
58362612	58362635	17	-	28162770	SKM1	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	0.1174567600429437	[72]	[139]	1	hSpCas9	negative selection	10565393
58360879	58360902	17	+	28162770	SKM1	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	-0.040641984497345796	[95]	[164]	0	hSpCas9	negative selection	10565394
58360804	58360827	17	+	28162770	SKM1	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	-0.9695588864358635	[71]	[64]	-6	hSpCas9	negative selection	10565395
58360197	58360220	17	+	28162770	SKM1	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.5703157247567548	[47]	[125]	5	hSpCas9	negative selection	10565396
58358737	58358760	17	+	28162770	SKM1	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-1.4069641987431614	[5]	[3]	-7	hSpCas9	negative selection	10565397
58358701	58358724	17	+	28162770	SKM1	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-0.03773038907744275	[17]	[30]	0	hSpCas9	negative selection	10565398
58358677	58358700	17	-	28162770	SKM1	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	0.06947384519982547	[68]	[127]	0	hSpCas9	negative selection	10565399
58415567	58415590	17	-	28162770	SKM1	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-0.448543302494561	[43]	[56]	-4	hSpCas9	negative selection	10734756
58358155	58358178	17	-	28162770	SKM1	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	0.44745897697122117	[55]	[134]	4	hSpCas9	negative selection	10734757
58415469	58415492	17	-	28162770	SKM1	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.735845054272291	[64]	[68]	-5	hSpCas9	negative selection	10734758
58362612	58362635	17	-	28162770	SKM1	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	0.1174567600429437	[72]	[139]	1	hSpCas9	negative selection	10734759
58360879	58360902	17	+	28162770	SKM1	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	-0.040641984497345796	[95]	[164]	0	hSpCas9	negative selection	10734760
58360804	58360827	17	+	28162770	SKM1	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	-0.9695588864358635	[71]	[64]	-6	hSpCas9	negative selection	10734761
58360197	58360220	17	+	28162770	SKM1	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.5703157247567548	[47]	[125]	5	hSpCas9	negative selection	10734762
58358737	58358760	17	+	28162770	SKM1	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-1.4069641987431614	[5]	[3]	-7	hSpCas9	negative selection	10734763
58358701	58358724	17	+	28162770	SKM1	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-0.03773038907744275	[17]	[30]	0	hSpCas9	negative selection	10734764
58358677	58358700	17	-	28162770	SKM1	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	0.06947384519982547	[68]	[127]	0	hSpCas9	negative selection	10734765
58415567	58415590	17	-	28162770	PL21	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	0.4191493964311158	[121]	[70]	3	hSpCas9	negative selection	10904122
58358155	58358178	17	-	28162770	PL21	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	0.0099557740632078	[250]	[109]	0	hSpCas9	negative selection	10904123
58415469	58415492	17	-	28162770	PL21	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.40000929004651203	[190]	[62]	-3	hSpCas9	negative selection	10904124
58362612	58362635	17	-	28162770	PL21	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	-0.3848228862318362	[269]	[89]	-3	hSpCas9	negative selection	10904125
58360879	58360902	17	+	28162770	PL21	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	-0.8298828686101315	[436]	[106]	-5	hSpCas9	negative selection	10904126
58360804	58360827	17	+	28162770	PL21	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	0.8949253931632277	[235]	[190]	7	hSpCas9	negative selection	10904127
58360197	58360220	17	+	28162770	PL21	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.17079565290717588	[148]	[72]	1	hSpCas9	negative selection	10904128
58358737	58358760	17	+	28162770	PL21	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-1.9153376029306166	[25]	[2]	-8	hSpCas9	negative selection	10904129
58358701	58358724	17	+	28162770	PL21	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	0.20013961448932016	[51]	[25]	1	hSpCas9	negative selection	10904130
58358677	58358700	17	-	28162770	PL21	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	0.8329968053147877	[315]	[244]	7	hSpCas9	negative selection	10904131
58415567	58415590	17	-	28162770	P31FUJ	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-0.16191871825786885	[138]	[145]	-1	hSpCas9	negative selection	11073488
58358155	58358178	17	-	28162770	P31FUJ	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	-0.3234047531952855	[344]	[323]	-3	hSpCas9	negative selection	11073489
58415469	58415492	17	-	28162770	P31FUJ	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	0.7040039690984276	[139]	[267]	7	hSpCas9	negative selection	11073490
58362612	58362635	17	-	28162770	P31FUJ	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	0.47320657720138215	[178]	[291]	5	hSpCas9	negative selection	11073491
58360879	58360902	17	+	28162770	P31FUJ	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	0.03575624789105225	[390]	[470]	0	hSpCas9	negative selection	11073492
58360804	58360827	17	+	28162770	P31FUJ	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	0.32662520419964014	[227]	[335]	3	hSpCas9	negative selection	11073493
58360197	58360220	17	+	28162770	P31FUJ	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.5783409781329333	[162]	[285]	6	hSpCas9	negative selection	11073494
58358737	58358760	17	+	28162770	P31FUJ	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	0.32359114411000656	[16]	[24]	3	hSpCas9	negative selection	11073495
58358701	58358724	17	+	28162770	P31FUJ	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-0.9800361340344121	[93]	[55]	-6	hSpCas9	negative selection	11073496
58358677	58358700	17	-	28162770	P31FUJ	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	-0.3728919763159281	[334]	[303]	-3	hSpCas9	negative selection	11073497
58415567	58415590	17	-	28162770	OCIAML5	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	0.39754731920747544	[89]	[213]	3	hSpCas9	negative selection	11242854
58358155	58358178	17	-	28162770	OCIAML5	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	0.5985948381455682	[164]	[450]	5	hSpCas9	negative selection	11242855
58415469	58415492	17	-	28162770	OCIAML5	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	0.4321418580742066	[61]	[150]	4	hSpCas9	negative selection	11242856
58362612	58362635	17	-	28162770	OCIAML5	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	0.6397865254656777	[127]	[359]	5	hSpCas9	negative selection	11242857
58360879	58360902	17	+	28162770	OCIAML5	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	-0.1318766894486177	[172]	[284]	-1	hSpCas9	negative selection	11242858
58360804	58360827	17	+	28162770	OCIAML5	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	0.2314981457751344	[108]	[230]	2	hSpCas9	negative selection	11242859
58360197	58360220	17	+	28162770	OCIAML5	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	-0.8138472486335067	[148]	[152]	-5	hSpCas9	negative selection	11242860
58358737	58358760	17	+	28162770	OCIAML5	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-1.0219915723063093	[8]	[7]	-6	hSpCas9	negative selection	11242861
58358701	58358724	17	+	28162770	OCIAML5	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-1.852066570863997	[57]	[28]	-7	hSpCas9	negative selection	11242862
58358677	58358700	17	-	28162770	OCIAML5	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	-0.18340699008869976	[172]	[274]	-1	hSpCas9	negative selection	11242863
58415567	58415590	17	-	28162770	EOL1	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	0.5939024595820632	[248]	[197]	5	hSpCas9	negative selection	11412220
58358155	58358178	17	-	28162770	EOL1	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	-0.2965559537973409	[372]	[159]	-2	hSpCas9	negative selection	11412221
58415469	58415492	17	-	28162770	EOL1	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.5900254012592238	[319]	[111]	-4	hSpCas9	negative selection	11412222
58362612	58362635	17	-	28162770	EOL1	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	-0.13773650668380816	[425]	[203]	-1	hSpCas9	negative selection	11412223
58360879	58360902	17	+	28162770	EOL1	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	0.5250600568092045	[768]	[582]	5	hSpCas9	negative selection	11412224
58360804	58360827	17	+	28162770	EOL1	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	-0.457224180846782	[442]	[169]	-3	hSpCas9	negative selection	11412225
58360197	58360220	17	+	28162770	EOL1	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	-0.569561298699508	[199]	[70]	-4	hSpCas9	negative selection	11412226
58358737	58358760	17	+	28162770	EOL1	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-1.0014516469856884	[18]	[4]	-6	hSpCas9	negative selection	11412227
58358701	58358724	17	+	28162770	EOL1	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-1.4957840273778222	[90]	[16]	-7	hSpCas9	negative selection	11412228
58358677	58358700	17	-	28162770	EOL1	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	0.17712781976716194	[276]	[164]	1	hSpCas9	negative selection	11412229
58415567	58415590	17	-	28162770	MOLM13	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	0.13433328440437703	[217]	[172]	0	hSpCas9	negative selection	11581586
58358155	58358178	17	-	28162770	MOLM13	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	0.6869804397907756	[249]	[290]	5	hSpCas9	negative selection	11581587
58415469	58415492	17	-	28162770	MOLM13	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	1.7173408151054477	[248]	[591]	9	hSpCas9	negative selection	11581588
58362612	58362635	17	-	28162770	MOLM13	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	-0.26641441289811263	[360]	[216]	-2	hSpCas9	negative selection	11581589
58360879	58360902	17	+	28162770	MOLM13	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	0.10495253082425116	[561]	[436]	0	hSpCas9	negative selection	11581590
58360804	58360827	17	+	28162770	MOLM13	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	0.6775605617796479	[357]	[413]	5	hSpCas9	negative selection	11581591
58360197	58360220	17	+	28162770	MOLM13	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	-1.7289113258891282	[297]	[64]	-7	hSpCas9	negative selection	11581592
58358737	58358760	17	+	28162770	MOLM13	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-4.81751283731767	[38]	[0]	-9	hSpCas9	negative selection	11581593
58358701	58358724	17	+	28162770	MOLM13	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-1.6379052824780178	[98]	[22]	-7	hSpCas9	negative selection	11581594
58358677	58358700	17	-	28162770	MOLM13	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	-0.44781238414876123	[348]	[184]	-3	hSpCas9	negative selection	11581595
58415567	58415590	17	-	28162770	HEL	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-2.2170835099513826	[195]	[26]	-8	hSpCas9	negative selection	11750952
58358155	58358178	17	-	28162770	HEL	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	0.3980052429095069	[281]	[237]	3	hSpCas9	negative selection	11750953
58415469	58415492	17	-	28162770	HEL	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	0.9442473856487865	[184]	[227]	7	hSpCas9	negative selection	11750954
58362612	58362635	17	-	28162770	HEL	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	0.4316839545981898	[337]	[291]	3	hSpCas9	negative selection	11750955
58360879	58360902	17	+	28162770	HEL	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	-0.1646160900572471	[531]	[303]	-1	hSpCas9	negative selection	11750956
58360804	58360827	17	+	28162770	HEL	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	0.14184059606767518	[374]	[264]	1	hSpCas9	negative selection	11750957
58360197	58360220	17	+	28162770	HEL	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.37803560580594486	[172]	[143]	3	hSpCas9	negative selection	11750958
58358737	58358760	17	+	28162770	HEL	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-1.1348687466631957	[23]	[6]	-6	hSpCas9	negative selection	11750959
58358701	58358724	17	+	28162770	HEL	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-1.0699792159191714	[58]	[17]	-6	hSpCas9	negative selection	11750960
58358677	58358700	17	-	28162770	HEL	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	0.11847226296675474	[255]	[177]	1	hSpCas9	negative selection	11750961
58415567	58415590	17	-	28162770	MV411	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	-0.30311491915254946	[144]	[98]	-2	hSpCas9	negative selection	11920318
58358155	58358178	17	-	28162770	MV411	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	-0.31979186401335846	[282]	[190]	-2	hSpCas9	negative selection	11920319
58415469	58415492	17	-	28162770	MV411	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	0.24743755078277524	[148]	[148]	2	hSpCas9	negative selection	11920320
58362612	58362635	17	-	28162770	MV411	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	-0.2368626109331822	[255]	[182]	-2	hSpCas9	negative selection	11920321
58360879	58360902	17	+	28162770	MV411	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	-0.06486962609169011	[410]	[330]	0	hSpCas9	negative selection	11920322
58360804	58360827	17	+	28162770	MV411	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	0.9092156485547622	[255]	[404]	7	hSpCas9	negative selection	11920323
58360197	58360220	17	+	28162770	MV411	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.7372428184635911	[93]	[131]	6	hSpCas9	negative selection	11920324
58358737	58358760	17	+	28162770	MV411	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-3.7525624492172245	[31]	[1]	-9	hSpCas9	negative selection	11920325
58358701	58358724	17	+	28162770	MV411	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	0.48350490901629994	[44]	[52]	4	hSpCas9	negative selection	11920326
58358677	58358700	17	-	28162770	MV411	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	0.3037755349325874	[225]	[234]	2	hSpCas9	negative selection	11920327
58415567	58415590	17	-	28162770	MONOMAC1	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	0.8972905354885994	[73]	[157]	8	hSpCas9	negative selection	12089684
58358155	58358178	17	-	28162770	MONOMAC1	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	-1.2476629201295215	[173]	[83]	-7	hSpCas9	negative selection	12089685
58415469	58415492	17	-	28162770	MONOMAC1	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-1.1254835860345198	[117]	[61]	-7	hSpCas9	negative selection	12089686
58362612	58362635	17	-	28162770	MONOMAC1	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	-0.33168637375433546	[201]	[183]	-3	hSpCas9	negative selection	12089687
58360879	58360902	17	+	28162770	MONOMAC1	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	0.33437618538486813	[246]	[356]	3	hSpCas9	negative selection	12089688
58360804	58360827	17	+	28162770	MONOMAC1	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	-0.5913157861716003	[137]	[104]	-5	hSpCas9	negative selection	12089689
58360197	58360220	17	+	28162770	MONOMAC1	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.7175716617098017	[86]	[163]	7	hSpCas9	negative selection	12089690
58358737	58358760	17	+	28162770	MONOMAC1	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-1.6564684656968511	[10]	[3]	-8	hSpCas9	negative selection	12089691
58358701	58358724	17	+	28162770	MONOMAC1	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-0.12664751916815598	[39]	[41]	-1	hSpCas9	negative selection	12089692
58358677	58358700	17	-	28162770	MONOMAC1	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	-0.06472955495542343	[176]	[193]	0	hSpCas9	negative selection	12089693
58415567	58415590	17	-	28162770	OCIAML2	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	0.031870515287022116	[20]	[118]	0	hSpCas9	negative selection	12259050
58358155	58358178	17	-	28162770	OCIAML2	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	0.10127652265354851	[36]	[219]	1	hSpCas9	negative selection	12259051
58415469	58415492	17	-	28162770	OCIAML2	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	-0.24823740390571347	[23]	[111]	-2	hSpCas9	negative selection	12259052
58362612	58362635	17	-	28162770	OCIAML2	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	0.2760837454756071	[58]	[395]	2	hSpCas9	negative selection	12259053
58360879	58360902	17	+	28162770	OCIAML2	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	-0.020733568751666098	[68]	[376]	0	hSpCas9	negative selection	12259054
58360804	58360827	17	+	28162770	OCIAML2	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	-0.00431182101962406	[37]	[209]	0	hSpCas9	negative selection	12259055
58360197	58360220	17	+	28162770	OCIAML2	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	-0.3621053684639921	[31]	[137]	-3	hSpCas9	negative selection	12259056
58358737	58358760	17	+	28162770	OCIAML2	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-2.956056652412403	[6]	[4]	-9	hSpCas9	negative selection	12259057
58358701	58358724	17	+	28162770	OCIAML2	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	2.173226364532563	[1]	[49]	9	hSpCas9	negative selection	12259058
58358677	58358700	17	-	28162770	OCIAML2	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	0.13652842159319112	[42]	[261]	1	hSpCas9	negative selection	12259059
58415567	58415590	17	-	28162770	OCIAML3	viability	GCAGCTGGTAGCATGAGTGGTGG	RNF43	ENSG00000108375	0.5913474016877552	[30]	[140]	5	hSpCas9	negative selection	12428416
58358155	58358178	17	-	28162770	OCIAML3	viability	GGACTCGGTGGTGCCCACAGGGG	RNF43	ENSG00000108375	0.09169983413681027	[105]	[340]	0	hSpCas9	negative selection	12428417
58415469	58415492	17	-	28162770	OCIAML3	viability	ACTGGTACTGGCAGCAGCGGTGG	RNF43	ENSG00000108375	0.4648860487294055	[35]	[149]	4	hSpCas9	negative selection	12428418
58362612	58362635	17	-	28162770	OCIAML3	viability	GTGGATCCTAATGACAGTGGTGG	RNF43	ENSG00000108375	0.2653940295030362	[69]	[253]	2	hSpCas9	negative selection	12428419
58360879	58360902	17	+	28162770	OCIAML3	viability	GCTGGCCTGGTACCTCCTGGTGG	RNF43	ENSG00000108375	-0.3196452286888565	[147]	[357]	-2	hSpCas9	negative selection	12428420
58360804	58360827	17	+	28162770	OCIAML3	viability	CAGACAGATGGCACACACAGGGG	RNF43	ENSG00000108375	0.2859159076840861	[71]	[264]	2	hSpCas9	negative selection	12428421
58360197	58360220	17	+	28162770	OCIAML3	viability	AGGGGTCCACACAGTTACGATGG	RNF43	ENSG00000108375	0.5392588905393011	[30]	[135]	5	hSpCas9	negative selection	12428422
58358737	58358760	17	+	28162770	OCIAML3	viability	CGGGATGCTGGCGAATGAGGTGG	RNF43	ENSG00000108375	-2.8164000616606115	[6]	[2]	-9	hSpCas9	negative selection	12428423
58358701	58358724	17	+	28162770	OCIAML3	viability	ACAGGTAGGCAGCAGGGAGGTGG	RNF43	ENSG00000108375	-2.117569596381176	[22]	[15]	-8	hSpCas9	negative selection	12428424
58358677	58358700	17	-	28162770	OCIAML3	viability	GGGCCCTTCCCGGAGTGCAGTGG	RNF43	ENSG00000108375	-0.7600175917630922	[68]	[122]	-5	hSpCas9	negative selection	12428425