Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 6195
  • Symbol: RPS6KA1
  • Description: ribosomal protein S6 kinase A1
DataSource: http://genomecrispr.dkfz.de/#!/results/RPS6KA1

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
26557006 26557029 CHR_HG2058_PATCH - 26472758 Jiyoye viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000281877 0.6406655117256519 [147] [173] 5 hSpCas9 negative selection 140212
26557006 26557029 1 - 26472758 Jiyoye viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 0.6406655117256519 [147] [173] 5 hSpCas9 negative selection 140213
26558823 26558846 CHR_HG2058_PATCH - 26472758 Jiyoye viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000281877 -1.3335817918227069 [126] [37] -7 hSpCas9 negative selection 140214
26558823 26558846 1 - 26472758 Jiyoye viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -1.3335817918227069 [126] [37] -7 hSpCas9 negative selection 140215
26547204 26547227 1 + 26472758 Jiyoye viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -0.6284485282248478 [40] [19] -4 hSpCas9 negative selection 140216
26547204 26547227 CHR_HG2058_PATCH + 26472758 Jiyoye viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000281877 -0.6284485282248478 [40] [19] -4 hSpCas9 negative selection 140217
26553384 26553407 1 + 26472758 Jiyoye viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 -0.08443664288057373 [186] [132] 0 hSpCas9 negative selection 140218
26553384 26553407 CHR_HG2058_PATCH + 26472758 Jiyoye viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000281877 -0.08443664288057373 [186] [132] 0 hSpCas9 negative selection 140219
26557022 26557045 1 - 26472758 Jiyoye viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 0.16293857112620563 [121] [102] 1 hSpCas9 negative selection 140220
26557022 26557045 CHR_HG2058_PATCH - 26472758 Jiyoye viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000281877 0.16293857112620563 [121] [102] 1 hSpCas9 negative selection 140221
26558910 26558933 CHR_HG2058_PATCH + 26472758 Jiyoye viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000281877 0.5105531213511821 [174] [187] 4 hSpCas9 negative selection 140222
26558910 26558933 1 + 26472758 Jiyoye viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 0.5105531213511821 [174] [187] 4 hSpCas9 negative selection 140223
26561535 26561558 CHR_HG2058_PATCH + 26472758 Jiyoye viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000281877 -0.7682666249040047 [130] [57] -5 hSpCas9 negative selection 140224
26561535 26561558 1 + 26472758 Jiyoye viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 -0.7682666249040047 [130] [57] -5 hSpCas9 negative selection 140225
26561585 26561608 1 + 26472758 Jiyoye viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 0.3719859530435735 [82] [80] 3 hSpCas9 negative selection 140226
26561585 26561608 CHR_HG2058_PATCH + 26472758 Jiyoye viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000281877 0.3719859530435735 [82] [80] 3 hSpCas9 negative selection 140227
26555164 26555187 CHR_HG2058_PATCH + 26472758 Jiyoye viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000281877 -0.518185817601371 [225] [118] -4 hSpCas9 negative selection 140228
26555164 26555187 1 + 26472758 Jiyoye viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -0.518185817601371 [225] [118] -4 hSpCas9 negative selection 140229
26555553 26555576 CHR_HG2058_PATCH - 26472758 Jiyoye viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000281877 -0.536241090127759 [124] [64] -4 hSpCas9 negative selection 140230
26555553 26555576 1 - 26472758 Jiyoye viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 -0.536241090127759 [124] [64] -4 hSpCas9 negative selection 140231
26557006 26557029 CHR_HG2058_PATCH - 26472758 KBM7 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000281877 -0.5944847460477657 [868,540] [245,187] -5 hSpCas9 negative selection 331330
26557006 26557029 1 - 26472758 KBM7 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 -0.5944847460477657 [868,540] [245,187] -5 hSpCas9 negative selection 331331
26558823 26558846 CHR_HG2058_PATCH - 26472758 KBM7 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000281877 -1.411469047047144 [281,156] [49,26] -7 hSpCas9 negative selection 331332
26558823 26558846 1 - 26472758 KBM7 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -1.411469047047144 [281,156] [49,26] -7 hSpCas9 negative selection 331333
26547204 26547227 1 + 26472758 KBM7 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -0.37072597310651223 [168,113] [84,19] -3 hSpCas9 negative selection 331334
26547204 26547227 CHR_HG2058_PATCH + 26472758 KBM7 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000281877 -0.37072597310651223 [168,113] [84,19] -3 hSpCas9 negative selection 331335
26553384 26553407 1 + 26472758 KBM7 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.19008477260032675 [844,698] [409,413] 2 hSpCas9 negative selection 331336
26553384 26553407 CHR_HG2058_PATCH + 26472758 KBM7 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000281877 0.19008477260032675 [844,698] [409,413] 2 hSpCas9 negative selection 331337
26557022 26557045 1 - 26472758 KBM7 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 -0.25763997186678855 [587,372] [221,152] -2 hSpCas9 negative selection 331338
26557022 26557045 CHR_HG2058_PATCH - 26472758 KBM7 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000281877 -0.25763997186678855 [587,372] [221,152] -2 hSpCas9 negative selection 331339
26558910 26558933 CHR_HG2058_PATCH + 26472758 KBM7 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000281877 0.5007539048021028 [784,387] [376,379] 5 hSpCas9 negative selection 331340
26558910 26558933 1 + 26472758 KBM7 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 0.5007539048021028 [784,387] [376,379] 5 hSpCas9 negative selection 331341
26561535 26561558 CHR_HG2058_PATCH + 26472758 KBM7 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000281877 -0.26937034842922347 [618,378] [146,229] -3 hSpCas9 negative selection 331342
26561535 26561558 1 + 26472758 KBM7 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 -0.26937034842922347 [618,378] [146,229] -3 hSpCas9 negative selection 331343
26561585 26561608 1 + 26472758 KBM7 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 -0.6610006428362236 [473,285] [125,96] -5 hSpCas9 negative selection 331344
26561585 26561608 CHR_HG2058_PATCH + 26472758 KBM7 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000281877 -0.6610006428362236 [473,285] [125,96] -5 hSpCas9 negative selection 331345
26555164 26555187 CHR_HG2058_PATCH + 26472758 KBM7 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000281877 0.06792729939950504 [1000,875] [373,539] 0 hSpCas9 negative selection 331346
26555164 26555187 1 + 26472758 KBM7 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 0.06792729939950504 [1000,875] [373,539] 0 hSpCas9 negative selection 331347
26555553 26555576 CHR_HG2058_PATCH - 26472758 KBM7 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000281877 0.603565490188001 [218,209] [244,71] 6 hSpCas9 negative selection 331348
26555553 26555576 1 - 26472758 KBM7 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 0.603565490188001 [218,209] [244,71] 6 hSpCas9 negative selection 331349
26557006 26557029 CHR_HG2058_PATCH - 26472758 Raji viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000281877 0.27836973218622235 [301] [84] 2 hSpCas9 negative selection 522448
26557006 26557029 1 - 26472758 Raji viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 0.27836973218622235 [301] [84] 2 hSpCas9 negative selection 522449
26558823 26558846 CHR_HG2058_PATCH - 26472758 Raji viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000281877 -0.5930561827674927 [168] [25] -5 hSpCas9 negative selection 522450
26558823 26558846 1 - 26472758 Raji viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -0.5930561827674927 [168] [25] -5 hSpCas9 negative selection 522451
26547204 26547227 1 + 26472758 Raji viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 0.8411034700361515 [88] [36] 7 hSpCas9 negative selection 522452
26547204 26547227 CHR_HG2058_PATCH + 26472758 Raji viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000281877 0.8411034700361515 [88] [36] 7 hSpCas9 negative selection 522453
26553384 26553407 1 + 26472758 Raji viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 -0.29651340630004386 [343] [64] -2 hSpCas9 negative selection 522454
26553384 26553407 CHR_HG2058_PATCH + 26472758 Raji viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000281877 -0.29651340630004386 [343] [64] -2 hSpCas9 negative selection 522455
26557022 26557045 1 - 26472758 Raji viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 -0.07641364065027048 [208] [45] 0 hSpCas9 negative selection 522456
26557022 26557045 CHR_HG2058_PATCH - 26472758 Raji viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000281877 -0.07641364065027048 [208] [45] 0 hSpCas9 negative selection 522457
26558910 26558933 CHR_HG2058_PATCH + 26472758 Raji viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000281877 1.1021278099221041 [274] [136] 8 hSpCas9 negative selection 522458
26558910 26558933 1 + 26472758 Raji viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 1.1021278099221041 [274] [136] 8 hSpCas9 negative selection 522459
26561535 26561558 CHR_HG2058_PATCH + 26472758 Raji viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000281877 -0.4415097106400348 [315] [53] -4 hSpCas9 negative selection 522460
26561535 26561558 1 + 26472758 Raji viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 -0.4415097106400348 [315] [53] -4 hSpCas9 negative selection 522461
26561585 26561608 1 + 26472758 Raji viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 -1.3706637614310446 [233] [20] -7 hSpCas9 negative selection 522462
26561585 26561608 CHR_HG2058_PATCH + 26472758 Raji viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000281877 -1.3706637614310446 [233] [20] -7 hSpCas9 negative selection 522463
26555164 26555187 CHR_HG2058_PATCH + 26472758 Raji viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000281877 -1.0133686240870108 [547] [62] -6 hSpCas9 negative selection 522464
26555164 26555187 1 + 26472758 Raji viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -1.0133686240870108 [547] [62] -6 hSpCas9 negative selection 522465
26555553 26555576 CHR_HG2058_PATCH - 26472758 Raji viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000281877 0.9769868981179246 [80] [36] 8 hSpCas9 negative selection 522466
26555553 26555576 1 - 26472758 Raji viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 0.9769868981179246 [80] [36] 8 hSpCas9 negative selection 522467
26557006 26557029 CHR_HG2058_PATCH - 26472758 K562 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000281877 0.19265729997670542 [453] [437] 1 hSpCas9 negative selection 713566
26557006 26557029 1 - 26472758 K562 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 0.19265729997670542 [453] [437] 1 hSpCas9 negative selection 713567
26558823 26558846 CHR_HG2058_PATCH - 26472758 K562 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000281877 -0.4513242037732461 [114] [70] -3 hSpCas9 negative selection 713568
26558823 26558846 1 - 26472758 K562 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -0.4513242037732461 [114] [70] -3 hSpCas9 negative selection 713569
26547204 26547227 1 + 26472758 K562 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -0.19918792380916783 [135] [99] -1 hSpCas9 negative selection 713570
26547204 26547227 CHR_HG2058_PATCH + 26472758 K562 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000281877 -0.19918792380916783 [135] [99] -1 hSpCas9 negative selection 713571
26553384 26553407 1 + 26472758 K562 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.608258449869074 [630] [811] 5 hSpCas9 negative selection 713572
26553384 26553407 CHR_HG2058_PATCH + 26472758 K562 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000281877 0.608258449869074 [630] [811] 5 hSpCas9 negative selection 713573
26557022 26557045 1 - 26472758 K562 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 -0.26273697360082826 [387] [272] -2 hSpCas9 negative selection 713574
26557022 26557045 CHR_HG2058_PATCH - 26472758 K562 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000281877 -0.26273697360082826 [387] [272] -2 hSpCas9 negative selection 713575
26558910 26558933 CHR_HG2058_PATCH + 26472758 K562 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000281877 0.09695139600207386 [493] [445] 0 hSpCas9 negative selection 713576
26558910 26558933 1 + 26472758 K562 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 0.09695139600207386 [493] [445] 0 hSpCas9 negative selection 713577
26561535 26561558 CHR_HG2058_PATCH + 26472758 K562 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000281877 0.5794424801654925 [328] [414] 5 hSpCas9 negative selection 713578
26561535 26561558 1 + 26472758 K562 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 0.5794424801654925 [328] [414] 5 hSpCas9 negative selection 713579
26561585 26561608 1 + 26472758 K562 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 0.16806784153633197 [290] [275] 1 hSpCas9 negative selection 713580
26561585 26561608 CHR_HG2058_PATCH + 26472758 K562 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000281877 0.16806784153633197 [290] [275] 1 hSpCas9 negative selection 713581
26555164 26555187 CHR_HG2058_PATCH + 26472758 K562 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000281877 -1.60041089980982 [818] [227] -7 hSpCas9 negative selection 713582
26555164 26555187 1 + 26472758 K562 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -1.60041089980982 [818] [227] -7 hSpCas9 negative selection 713583
26555553 26555576 CHR_HG2058_PATCH - 26472758 K562 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000281877 0.5479682932389546 [157] [194] 4 hSpCas9 negative selection 713584
26555553 26555576 1 - 26472758 K562 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 0.5479682932389546 [157] [194] 4 hSpCas9 negative selection 713585
26529946 26529969 1 - 26627737 DLD1 viability CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 1.2992242009574266 [99] [64,69,92] 9 hSpCas9 negative selection 770444
26543207 26543230 1 - 26627737 DLD1 viability CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 -0.38281790217121014 [1080] [255,223,290] -4 hSpCas9 negative selection 770445
26544153 26544176 1 - 26627737 DLD1 viability GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 0.11163564483898658 [212] [159,27,31] 1 hSpCas9 negative selection 770446
26546023 26546046 1 - 26627737 DLD1 viability GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 0.676387779328433 [343] [80,273,165] 6 hSpCas9 negative selection 770447
26546894 26546917 1 + 26627737 DLD1 viability ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.5849056862149464 [517] [393,156,182] 6 hSpCas9 negative selection 770448
26551404 26551427 1 - 26627737 DLD1 viability TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 -0.17146962348251138 [408] [140,117,85] -2 hSpCas9 negative selection 770449
26529946 26529969 1 - 26627737 GBM cells viability after 5 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -0.8219320539172438 [177] [77,29] -8 hSpCas9 negative selection 852759
26543207 26543230 1 - 26627737 GBM cells viability after 5 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.07830285612581456 [573] [307,341] 1 hSpCas9 negative selection 852760
26544153 26544176 1 - 26627737 GBM cells viability after 5 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -0.08459800232574577 [86] [57,29] -1 hSpCas9 negative selection 852761
26546023 26546046 1 - 26627737 GBM cells viability after 5 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 0.5180090605259878 [180] [110,166] 7 hSpCas9 negative selection 852762
26546894 26546917 1 + 26627737 GBM cells viability after 5 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.09745955426776604 [304] [181,167] 1 hSpCas9 negative selection 852763
26551404 26551427 1 - 26627737 GBM cells viability after 5 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 0.3438284154991452 [226] [135,172] 5 hSpCas9 negative selection 852764
26529946 26529969 1 - 26627737 GBM cells viability after 13 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -1.258765524663732 [177] [73,12] -8 hSpCas9 negative selection 935074
26543207 26543230 1 - 26627737 GBM cells viability after 13 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.18369256954048918 [573] [436,285] 2 hSpCas9 negative selection 935075
26544153 26544176 1 - 26627737 GBM cells viability after 13 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -0.7079896163746515 [86] [29,27] -7 hSpCas9 negative selection 935076
26546023 26546046 1 - 26627737 GBM cells viability after 13 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 0.288882606431373 [180] [146,97] 3 hSpCas9 negative selection 935077
26546894 26546917 1 + 26627737 GBM cells viability after 13 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.316077691806521 [304] [197,79] -4 hSpCas9 negative selection 935078
26551404 26551427 1 - 26627737 GBM cells viability after 13 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 0.25052870408614947 [226] [156,137] 3 hSpCas9 negative selection 935079
26529946 26529969 1 - 26627737 GBM cells viability after 21 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -1.5895013907292963 [177] [28,34] -8 hSpCas9 negative selection 1017389
26543207 26543230 1 - 26627737 GBM cells viability after 21 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.0815514327333513 [573] [353,307] 0 hSpCas9 negative selection 1017390
26544153 26544176 1 - 26627737 GBM cells viability after 21 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -0.4407738280901643 [86] [38,30] -4 hSpCas9 negative selection 1017391
26546023 26546046 1 - 26627737 GBM cells viability after 21 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 0.7462237890767962 [180] [177,152] 7 hSpCas9 negative selection 1017392
26546894 26546917 1 + 26627737 GBM cells viability after 21 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -1.2814376006139974 [304] [75,60] -8 hSpCas9 negative selection 1017393
26551404 26551427 1 - 26627737 GBM cells viability after 21 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 0.007363935023380883 [226] [124,122] 0 hSpCas9 negative selection 1017394
26529946 26529969 1 - 26627737 RPE1 viability after 9 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 1.160799398725083 [313] [114,354] 7 hSpCas9 negative selection 1099704
26543207 26543230 1 - 26627737 RPE1 viability after 9 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.6068733794433512 [1419] [356,1089] 4 hSpCas9 negative selection 1099705
26544153 26544176 1 - 26627737 RPE1 viability after 9 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -0.37028970447889076 [514] [177,55] -3 hSpCas9 negative selection 1099706
26546023 26546046 1 - 26627737 RPE1 viability after 9 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 1.3011745680829403 [66] [52,49] 7 hSpCas9 negative selection 1099707
26546894 26546917 1 + 26627737 RPE1 viability after 9 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 3.534158154604908 [92] [266,427] 9 hSpCas9 negative selection 1099708
26551404 26551427 1 - 26627737 RPE1 viability after 9 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 1.18056392476145 [328] [91,415] 7 hSpCas9 negative selection 1099709
26529946 26529969 1 - 26627737 RPE1 viability after 12 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 0.9605499233690682 [313] [152,175] 6 hSpCas9 negative selection 1182019
26543207 26543230 1 - 26627737 RPE1 viability after 12 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.3655257357267443 [1419] [372,616] 2 hSpCas9 negative selection 1182020
26544153 26544176 1 - 26627737 RPE1 viability after 12 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -1.2261851749557215 [514] [63,53] -7 hSpCas9 negative selection 1182021
26546023 26546046 1 - 26627737 RPE1 viability after 12 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 0.6329539562387843 [66] [24,30] 4 hSpCas9 negative selection 1182022
26546894 26546917 1 + 26627737 RPE1 viability after 12 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 3.5264481645757946 [92] [284,290] 9 hSpCas9 negative selection 1182023
26551404 26551427 1 - 26627737 RPE1 viability after 12 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 0.7869682111348962 [328] [186,115] 5 hSpCas9 negative selection 1182024
26529946 26529969 1 - 26627737 RPE1 viability after 15 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 0.8182102529148705 [313] [121,189] 5 hSpCas9 negative selection 1264334
26543207 26543230 1 - 26627737 RPE1 viability after 15 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 -0.0896021527334323 [1419] [236,512] 0 hSpCas9 negative selection 1264335
26544153 26544176 1 - 26627737 RPE1 viability after 15 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -1.7869209418509966 [514] [29,53] -8 hSpCas9 negative selection 1264336
26546023 26546046 1 - 26627737 RPE1 viability after 15 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 0.17156392651049845 [66] [29,12] 1 hSpCas9 negative selection 1264337
26546894 26546917 1 + 26627737 RPE1 viability after 15 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 3.420415779379248 [92] [159,398] 9 hSpCas9 negative selection 1264338
26551404 26551427 1 - 26627737 RPE1 viability after 15 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 0.23991801443728344 [328] [58,158] 1 hSpCas9 negative selection 1264339
26529946 26529969 1 - 26627737 RPE1 viability after 18 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 0.9252847343733117 [313] [114,209] 5 hSpCas9 negative selection 1346649
26543207 26543230 1 - 26627737 RPE1 viability after 18 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.3729335603497075 [1419] [357,643] 2 hSpCas9 negative selection 1346650
26544153 26544176 1 - 26627737 RPE1 viability after 18 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -1.2525508223434785 [514] [67,47] -6 hSpCas9 negative selection 1346651
26546023 26546046 1 - 26627737 RPE1 viability after 18 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 1.0595819224980714 [66] [13,62] 6 hSpCas9 negative selection 1346652
26546894 26546917 1 + 26627737 RPE1 viability after 18 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 2.9300130681713656 [92] [140,244] 9 hSpCas9 negative selection 1346653
26551404 26551427 1 - 26627737 RPE1 viability after 18 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 0.6487300634180524 [328] [144,132] 4 hSpCas9 negative selection 1346654
26529946 26529969 1 - 26627737 HeLa viability after 8 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 0.7717153972165728 [268] [239,14,342] 6 hSpCas9 negative selection 1428964
26543207 26543230 1 - 26627737 HeLa viability after 8 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 -0.4158055557383372 [1044] [341,401,282] -4 hSpCas9 negative selection 1428965
26544153 26544176 1 - 26627737 HeLa viability after 8 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 0.09466816310609305 [136] [138,55,15] 0 hSpCas9 negative selection 1428966
26546023 26546046 1 - 26627737 HeLa viability after 8 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 -0.27679054851279505 [354] [170,32,183] -3 hSpCas9 negative selection 1428967
26546894 26546917 1 + 26627737 HeLa viability after 8 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.6082489847071806 [266] [156,223,147] 5 hSpCas9 negative selection 1428968
26551404 26551427 1 - 26627737 HeLa viability after 8 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 -0.18205646610859771 [277] [144,145,41] -2 hSpCas9 negative selection 1428969
26529946 26529969 1 - 26627737 HeLa viability after 12 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 0.014950990115050411 [268] [27,88,219] 0 hSpCas9 negative selection 1511279
26543207 26543230 1 - 26627737 HeLa viability after 12 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.41397991153143265 [1044] [588,410,743] 3 hSpCas9 negative selection 1511280
26544153 26544176 1 - 26627737 HeLa viability after 12 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -0.21377159105659094 [136] [29,47,67] -2 hSpCas9 negative selection 1511281
26546023 26546046 1 - 26627737 HeLa viability after 12 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 -1.062331211513783 [354] [155,15,46] -7 hSpCas9 negative selection 1511282
26546894 26546917 1 + 26627737 HeLa viability after 12 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.43696055796810596 [266] [224,142,82] 4 hSpCas9 negative selection 1511283
26551404 26551427 1 - 26627737 HeLa viability after 12 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 0.4151775687671999 [277] [69,135,252] 3 hSpCas9 negative selection 1511284
26529946 26529969 1 - 26627737 HeLa viability after 15 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -0.5908835819796486 [268] [22,83,114] -5 hSpCas9 negative selection 1593594
26543207 26543230 1 - 26627737 HeLa viability after 15 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.0860775769968174 [1044] [360,360,648] 0 hSpCas9 negative selection 1593595
26544153 26544176 1 - 26627737 HeLa viability after 15 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 0.7548650691894438 [136] [4,129,152] 6 hSpCas9 negative selection 1593596
26546023 26546046 1 - 26627737 HeLa viability after 15 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 0.6648044647508848 [354] [279,185,219] 5 hSpCas9 negative selection 1593597
26546894 26546917 1 + 26627737 HeLa viability after 15 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.6346658106386489 [266] [236,188,71] 5 hSpCas9 negative selection 1593598
26551404 26551427 1 - 26627737 HeLa viability after 15 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 0.8135643889136276 [277] [59,200,348] 6 hSpCas9 negative selection 1593599
26529946 26529969 1 - 26627737 HeLa viability after 18 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -0.6184382192782824 [268] [9,72,114] -5 hSpCas9 negative selection 1675909
26543207 26543230 1 - 26627737 HeLa viability after 18 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.09041837781144113 [1044] [243,299,648] 0 hSpCas9 negative selection 1675910
26544153 26544176 1 - 26627737 HeLa viability after 18 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 0.7993324721080801 [136] [3,113,152] 6 hSpCas9 negative selection 1675911
26546023 26546046 1 - 26627737 HeLa viability after 18 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 0.696561068628675 [354] [188,164,219] 5 hSpCas9 negative selection 1675912
26546894 26546917 1 + 26627737 HeLa viability after 18 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.6195705017141182 [266] [159,150,71] 5 hSpCas9 negative selection 1675913
26551404 26551427 1 - 26627737 HeLa viability after 18 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 0.7818804389276144 [277] [36,159,348] 6 hSpCas9 negative selection 1675914
26529946 26529969 1 - 26627737 HCT116 viability after 6 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -0.8966459017167323 [431] [98,1] -5 hSpCas9 negative selection 1758224
26543207 26543230 1 - 26627737 HCT116 viability after 6 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 -0.01549388589114209 [1121] [227,144] 0 hSpCas9 negative selection 1758225
26544153 26544176 1 - 26627737 HCT116 viability after 6 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -1.5030690824218431 [110] [0,8] -7 hSpCas9 negative selection 1758226
26546023 26546046 1 - 26627737 HCT116 viability after 6 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 1.3263155375060447 [941] [400,354] 7 hSpCas9 negative selection 1758227
26546894 26546917 1 + 26627737 HCT116 viability after 6 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.948959214056009 [479] [242,91] 5 hSpCas9 negative selection 1758228
26551404 26551427 1 - 26627737 HCT116 viability after 6 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 1.7792770388663066 [206] [306,3] 8 hSpCas9 negative selection 1758229
26529946 26529969 1 - 26627737 HCT116 viability after 8 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -1.0541003333872694 [224] [58,50,68] -8 hSpCas9 negative selection 1840539
26543207 26543230 1 - 26627737 HCT116 viability after 8 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.5487198715262848 [402] [289,451,232] 5 hSpCas9 negative selection 1840540
26544153 26544176 1 - 26627737 HCT116 viability after 8 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -0.6844839770658137 [179] [18,71,92] -7 hSpCas9 negative selection 1840541
26546023 26546046 1 - 26627737 HCT116 viability after 8 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 0.39599649324359965 [119] [131,56,72] 4 hSpCas9 negative selection 1840542
26546894 26546917 1 + 26627737 HCT116 viability after 8 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.5660800650773437 [469] [147,175,199] -6 hSpCas9 negative selection 1840543
26551404 26551427 1 - 26627737 HCT116 viability after 8 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 -0.6307882471042684 [290] [156,81,72] -6 hSpCas9 negative selection 1840544
26529946 26529969 1 - 26627737 HCT116 viability after 9 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -1.9825354593881186 [431] [55,7] -8 hSpCas9 negative selection 1922854
26543207 26543230 1 - 26627737 HCT116 viability after 9 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.4031457484323313 [1121] [465,340] 3 hSpCas9 negative selection 1922855
26544153 26544176 1 - 26627737 HCT116 viability after 9 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 1.4630449140691417 [110] [31,120] 8 hSpCas9 negative selection 1922856
26546023 26546046 1 - 26627737 HCT116 viability after 9 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 -1.0430040734808244 [941] [149,99] -6 hSpCas9 negative selection 1922857
26546894 26546917 1 + 26627737 HCT116 viability after 9 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.2674154695917637 [479] [227,95] 2 hSpCas9 negative selection 1922858
26551404 26551427 1 - 26627737 HCT116 viability after 9 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 1.8861563950387752 [206] [248,168] 9 hSpCas9 negative selection 1922859
26529946 26529969 1 - 26627737 HCT116 viability after 12 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -1.5274339707329334 [224] [32,50,39] -9 hSpCas9 negative selection 2005169
26543207 26543230 1 - 26627737 HCT116 viability after 12 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.8333847791091484 [402] [280,517,344] 7 hSpCas9 negative selection 2005170
26544153 26544176 1 - 26627737 HCT116 viability after 12 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -0.5573349700033349 [179] [22,85,87] -6 hSpCas9 negative selection 2005171
26546023 26546046 1 - 26627737 HCT116 viability after 12 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 1.3647394130753705 [119] [243,118,115] 9 hSpCas9 negative selection 2005172
26546894 26546917 1 + 26627737 HCT116 viability after 12 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.09987607666097809 [469] [174,223,401] 1 hSpCas9 negative selection 2005173
26551404 26551427 1 - 26627737 HCT116 viability after 12 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 -0.6233374342180504 [290] [97,142,57] -6 hSpCas9 negative selection 2005174
26529946 26529969 1 - 26627737 HCT116 viability after 15 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -0.9946893760151546 [224] [45,60,84] -7 hSpCas9 negative selection 2087484
26543207 26543230 1 - 26627737 HCT116 viability after 15 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.4565753862948174 [402] [250,400,292] 4 hSpCas9 negative selection 2087485
26544153 26544176 1 - 26627737 HCT116 viability after 15 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -0.8550772484273524 [179] [16,45,102] -7 hSpCas9 negative selection 2087486
26546023 26546046 1 - 26627737 HCT116 viability after 15 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 0.420329305231107 [119] [199,14,74] 4 hSpCas9 negative selection 2087487
26546894 26546917 1 + 26627737 HCT116 viability after 15 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.23232993583488076 [469] [211,232,241] -2 hSpCas9 negative selection 2087488
26551404 26551427 1 - 26627737 HCT116 viability after 15 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 -0.5944927098831332 [290] [113,153,64] -6 hSpCas9 negative selection 2087489
26529946 26529969 1 - 26627737 HCT116 viability after 18 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -1.581280997598721 [224] [27,5,78] -8 hSpCas9 negative selection 2169799
26543207 26543230 1 - 26627737 HCT116 viability after 18 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 -0.11275862723586788 [402] [196,177,164] -1 hSpCas9 negative selection 2169800
26544153 26544176 1 - 26627737 HCT116 viability after 18 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -0.489871422050289 [179] [13,37,138] -4 hSpCas9 negative selection 2169801
26546023 26546046 1 - 26627737 HCT116 viability after 18 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 1.4430945849536971 [119] [195,6,285] 8 hSpCas9 negative selection 2169802
26546894 26546917 1 + 26627737 HCT116 viability after 18 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.09236295228975466 [469] [75,229,337] -1 hSpCas9 negative selection 2169803
26551404 26551427 1 - 26627737 HCT116 viability after 18 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 -0.6852224287158034 [290] [128,65,67] -6 hSpCas9 negative selection 2169804
26546863 26546886 1 + 24336569 HL60 viability TCAGGATGAGGGCGTCCTCAAGG RPS6KA1 ENSG00000117676 0.10038192640675492 [1231] [2794] 1 hSpCas9 negative selection 2292958
26546878 26546901 1 - 24336569 HL60 viability GCGTGATGGAGATCTCCTTGAGG RPS6KA1 ENSG00000117676 -1.1208306642163748 [742] [722] -7 hSpCas9 negative selection 2292959
26546890 26546913 1 + 24336569 HL60 viability CTCCATCACGCACCACGTCAAGG RPS6KA1 ENSG00000117676 -0.3282936346062091 [902] [1521] -3 hSpCas9 negative selection 2292960
26546902 26546925 1 - 24336569 HL60 viability TCTCAGAGCCAGCCTTGACGTGG RPS6KA1 ENSG00000117676 -0.1650077414119095 [470] [888] -1 hSpCas9 negative selection 2292961
26546933 26546956 1 - 24336569 HL60 viability TTGAGGAGCTCGAAATGGGATGG RPS6KA1 ENSG00000117676 0.13508851680009937 [777] [1807] 1 hSpCas9 negative selection 2292962
26546938 26546961 1 - 24336569 HL60 viability GAACCTTGAGGAGCTCGAAATGG RPS6KA1 ENSG00000117676 0.7930050172872448 [356] [1308] 6 hSpCas9 negative selection 2292963
26546947 26546970 1 + 24336569 HL60 viability GCTCCTCAAGGTTCTGGGCCAGG RPS6KA1 ENSG00000117676 0.5572863647384476 [350] [1092] 5 hSpCas9 negative selection 2292964
26546957 26546980 1 + 24336569 HL60 viability GTTCTGGGCCAGGGATCCTTTGG RPS6KA1 ENSG00000117676 1.177270167771272 [307] [1473] 8 hSpCas9 negative selection 2292965
26546965 26546988 1 - 24336569 HL60 viability TCACTTTGCCAAAGGATCCCTGG RPS6KA1 ENSG00000117676 0.017711304461939137 [800] [1715] 0 hSpCas9 negative selection 2292966
26546973 26546996 1 - 24336569 HL60 viability CTCATGACTCACTTTGCCAAAGG RPS6KA1 ENSG00000117676 0.36651749726486293 [643] [1756] 3 hSpCas9 negative selection 2292967
26546863 26546886 1 + 24336569 KBM7 viability TCAGGATGAGGGCGTCCTCAAGG RPS6KA1 ENSG00000117676 -0.21465038047859286 [915] [2152] -2 hSpCas9 negative selection 2360135
26546878 26546901 1 - 24336569 KBM7 viability GCGTGATGGAGATCTCCTTGAGG RPS6KA1 ENSG00000117676 -0.5967782171172298 [513] [926] -5 hSpCas9 negative selection 2360136
26546890 26546913 1 + 24336569 KBM7 viability CTCCATCACGCACCACGTCAAGG RPS6KA1 ENSG00000117676 0.8729452708164849 [616] [3081] 7 hSpCas9 negative selection 2360137
26546902 26546925 1 - 24336569 KBM7 viability TCTCAGAGCCAGCCTTGACGTGG RPS6KA1 ENSG00000117676 -0.5197912600470984 [296] [564] -4 hSpCas9 negative selection 2360138
26546933 26546956 1 - 24336569 KBM7 viability TTGAGGAGCTCGAAATGGGATGG RPS6KA1 ENSG00000117676 0.26970478813861537 [523] [1722] 2 hSpCas9 negative selection 2360139
26546938 26546961 1 - 24336569 KBM7 viability GAACCTTGAGGAGCTCGAAATGG RPS6KA1 ENSG00000117676 -0.5297118238383518 [514] [972] -4 hSpCas9 negative selection 2360140
26546947 26546970 1 + 24336569 KBM7 viability GCTCCTCAAGGTTCTGGGCCAGG RPS6KA1 ENSG00000117676 0.9213268396198255 [283] [1466] 7 hSpCas9 negative selection 2360141
26546957 26546980 1 + 24336569 KBM7 viability GTTCTGGGCCAGGGATCCTTTGG RPS6KA1 ENSG00000117676 0.7090642837880768 [387] [1729] 6 hSpCas9 negative selection 2360142
26546965 26546988 1 - 24336569 KBM7 viability TCACTTTGCCAAAGGATCCCTGG RPS6KA1 ENSG00000117676 0.24949367049381094 [494] [1604] 2 hSpCas9 negative selection 2360143
26546973 26546996 1 - 24336569 KBM7 viability CTCATGACTCACTTTGCCAAAGG RPS6KA1 ENSG00000117676 1.4709226894299245 [329] [2494] 9 hSpCas9 negative selection 2360144
26545726 26545749 1 + 25494202 A375 resistance to PLX-4720 (puromycin) ACGTGGTGAGGGTGTAGGCCTGG RPS6KA1 ENSG00000117676 0.9420140257574894 [99,68] [2,69] 4 dCas9-VP64 positive selection 2388014
26545726 26545749 CHR_HG2058_PATCH + 25494202 A375 resistance to PLX-4720 (puromycin) ACGTGGTGAGGGTGTAGGCCTGG RPS6KA1 ENSG00000281877 0.9420140257574894 [99,68] [2,69] 4 dCas9-VP64 positive selection 2388015
26545680 26545703 1 + 25494202 A375 resistance to PLX-4720 (puromycin) AGGGCAGCCCTCAGGCTCTGAGG RPS6KA1 ENSG00000117676 0.32118399264726416 [13,41] [4,9] 1 dCas9-VP64 positive selection 2388016
26545680 26545703 CHR_HG2058_PATCH + 25494202 A375 resistance to PLX-4720 (puromycin) AGGGCAGCCCTCAGGCTCTGAGG RPS6KA1 ENSG00000281877 0.32118399264726416 [13,41] [4,9] 1 dCas9-VP64 positive selection 2388017
26545744 26545767 CHR_HG2058_PATCH - 25494202 A375 resistance to PLX-4720 (puromycin) GCCTGTGGTTTCCCAGCACCAGG RPS6KA1 ENSG00000281877 -0.17768848041268104 [387,405] [46,109] 0 dCas9-VP64 positive selection 2388018
26545744 26545767 1 - 25494202 A375 resistance to PLX-4720 (puromycin) GCCTGTGGTTTCCCAGCACCAGG RPS6KA1 ENSG00000117676 -0.17768848041268104 [387,405] [46,109] 0 dCas9-VP64 positive selection 2388019
26573846 26573869 1 + 25494202 A375 resistance to PLX-4720 (puromycin) GAGAATCGCTTGAACCCTGGGGG RPS6KA1 ENSG00000117676 -0.5583774166941213 [49,17] [4,3] -3 dCas9-VP64 positive selection 2470296
26573846 26573869 CHR_HG2058_PATCH + 25494202 A375 resistance to PLX-4720 (puromycin) GAGAATCGCTTGAACCCTGGGGG RPS6KA1 ENSG00000281877 -0.5583774166941213 [49,17] [4,3] -3 dCas9-VP64 positive selection 2470297
26545726 26545749 1 + 25494202 A375 resistance to PLX-4720 (zeocin) ACGTGGTGAGGGTGTAGGCCTGG RPS6KA1 ENSG00000117676 -0.8066384836784739 [472,69] [91,12] -7 dCas9-VP64 positive selection 2483269
26545726 26545749 CHR_HG2058_PATCH + 25494202 A375 resistance to PLX-4720 (zeocin) ACGTGGTGAGGGTGTAGGCCTGG RPS6KA1 ENSG00000281877 -0.8066384836784739 [472,69] [91,12] -7 dCas9-VP64 positive selection 2483270
26545680 26545703 1 + 25494202 A375 resistance to PLX-4720 (zeocin) AGGGCAGCCCTCAGGCTCTGAGG RPS6KA1 ENSG00000117676 -0.19941171735615293 [75,36] [23,7] -2 dCas9-VP64 positive selection 2483271
26545680 26545703 CHR_HG2058_PATCH + 25494202 A375 resistance to PLX-4720 (zeocin) AGGGCAGCCCTCAGGCTCTGAGG RPS6KA1 ENSG00000281877 -0.19941171735615293 [75,36] [23,7] -2 dCas9-VP64 positive selection 2483272
26545744 26545767 CHR_HG2058_PATCH - 25494202 A375 resistance to PLX-4720 (zeocin) GCCTGTGGTTTCCCAGCACCAGG RPS6KA1 ENSG00000281877 0.708672616513528 [78,104] [84,14] 5 dCas9-VP64 positive selection 2483273
26545744 26545767 1 - 25494202 A375 resistance to PLX-4720 (zeocin) GCCTGTGGTTTCCCAGCACCAGG RPS6KA1 ENSG00000117676 0.708672616513528 [78,104] [84,14] 5 dCas9-VP64 positive selection 2483274
26573846 26573869 1 + 25494202 A375 resistance to PLX-4720 (zeocin) GAGAATCGCTTGAACCCTGGGGG RPS6KA1 ENSG00000117676 -1.4985881155418108 [182,12] [19,2] -9 dCas9-VP64 positive selection 2565551
26573846 26573869 CHR_HG2058_PATCH + 25494202 A375 resistance to PLX-4720 (zeocin) GAGAATCGCTTGAACCCTGGGGG RPS6KA1 ENSG00000281877 -1.4985881155418108 [182,12] [19,2] -9 dCas9-VP64 positive selection 2565552
26529973 26529996 1 + 27013184 SW480 treatment with recombinant TRAIL TGGACCCGGAGGTGAGTGAGCGG RPS6KA1 ENSG00000117676 -0.5388383315282738 [137,83] [43,18] -2 hSpCas9 positive selection 2958352
26529973 26529996 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL TGGACCCGGAGGTGAGTGAGCGG RPS6KA1 ENSG00000281877 -0.5388383315282738 [137,83] [43,18] -2 hSpCas9 positive selection 2958353
26546890 26546913 1 + 27013184 SW480 treatment with recombinant TRAIL CTCCATCACGCACCACGTCAAGG RPS6KA1 ENSG00000117676 0.19441020088385164 [164,321] [103,134] 1 hSpCas9 positive selection 2958354
26546890 26546913 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL CTCCATCACGCACCACGTCAAGG RPS6KA1 ENSG00000281877 0.19441020088385164 [164,321] [103,134] 1 hSpCas9 positive selection 2958355
26546894 26546917 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000281877 0.44659406514292677 [31,36] [1,45] 2 hSpCas9 positive selection 2958356
26546894 26546917 1 + 27013184 SW480 treatment with recombinant TRAIL ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.44659406514292677 [31,36] [1,45] 2 hSpCas9 positive selection 2958357
26546905 26546928 1 + 27013184 SW480 treatment with recombinant TRAIL CGTCAAGGCTGGCTCTGAGAAGG RPS6KA1 ENSG00000117676 -0.6073189059745234 [264,593] [93,150] -3 hSpCas9 positive selection 2958358
26546905 26546928 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL CGTCAAGGCTGGCTCTGAGAAGG RPS6KA1 ENSG00000281877 -0.6073189059745234 [264,593] [93,150] -3 hSpCas9 positive selection 2958359
26551440 26551463 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL TGATGTAAATCACCCATTCGTGG RPS6KA1 ENSG00000281877 0.3905154726100356 [72,112] [70,23] 2 hSpCas9 positive selection 2958360
26551440 26551463 1 + 27013184 SW480 treatment with recombinant TRAIL TGATGTAAATCACCCATTCGTGG RPS6KA1 ENSG00000117676 0.3905154726100356 [72,112] [70,23] 2 hSpCas9 positive selection 2958361
26546947 26546970 1 + 27013184 SW480 treatment with recombinant TRAIL GCTCCTCAAGGTTCTGGGCCAGG RPS6KA1 ENSG00000117676 -0.40120193106106605 [523,367] [199,73] -2 hSpCas9 positive selection 2958362
26546947 26546970 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL GCTCCTCAAGGTTCTGGGCCAGG RPS6KA1 ENSG00000281877 -0.40120193106106605 [523,367] [199,73] -2 hSpCas9 positive selection 2958363
26546948 26546971 1 + 27013184 SW480 treatment with recombinant TRAIL CTCCTCAAGGTTCTGGGCCAGGG RPS6KA1 ENSG00000117676 -0.9391780241800474 [665,711] [121,200] -4 hSpCas9 positive selection 2958364
26546948 26546971 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL CTCCTCAAGGTTCTGGGCCAGGG RPS6KA1 ENSG00000281877 -0.9391780241800474 [665,711] [121,200] -4 hSpCas9 positive selection 2958365
26547205 26547228 1 + 27013184 SW480 treatment with recombinant TRAIL AAGTCACCCGGCCTGACAGTGGG RPS6KA1 ENSG00000117676 3.2777205517863828 [40,32] [216,69] 9 hSpCas9 positive selection 2958366
26547205 26547228 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL AAGTCACCCGGCCTGACAGTGGG RPS6KA1 ENSG00000281877 3.2777205517863828 [40,32] [216,69] 9 hSpCas9 positive selection 2958367
26547224 26547247 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL TGGGCACCTGTATGCTATGAAGG RPS6KA1 ENSG00000281877 0.896916040177042 [418,604] [268,597] 4 hSpCas9 positive selection 2958368
26547224 26547247 1 + 27013184 SW480 treatment with recombinant TRAIL TGGGCACCTGTATGCTATGAAGG RPS6KA1 ENSG00000117676 0.896916040177042 [418,604] [268,597] 4 hSpCas9 positive selection 2958369
26547256 26547279 1 + 27013184 SW480 treatment with recombinant TRAIL AGGCAACGCTGAAAGGTGAGTGG RPS6KA1 ENSG00000117676 4.228847897509494 [1,3] [11,39] 9 hSpCas9 positive selection 2958370
26547256 26547279 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL AGGCAACGCTGAAAGGTGAGTGG RPS6KA1 ENSG00000281877 4.228847897509494 [1,3] [11,39] 9 hSpCas9 positive selection 2958371
26547257 26547280 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL GGCAACGCTGAAAGGTGAGTGGG RPS6KA1 ENSG00000281877 1.5328998057051808 [55,26] [45,63] 7 hSpCas9 positive selection 2958372
26547257 26547280 1 + 27013184 SW480 treatment with recombinant TRAIL GGCAACGCTGAAAGGTGAGTGGG RPS6KA1 ENSG00000117676 1.5328998057051808 [55,26] [45,63] 7 hSpCas9 positive selection 2958373
26529920 26529943 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL GATGCCGCTCGCCCAGCTCAAGG RPS6KA1 ENSG00000281877 0.6688897339744737 [493,765] [295,605] 3 hSpCas9 positive selection 2958374
26529920 26529943 1 + 27013184 SW480 treatment with recombinant TRAIL GATGCCGCTCGCCCAGCTCAAGG RPS6KA1 ENSG00000117676 0.6688897339744737 [493,765] [295,605] 3 hSpCas9 positive selection 2958375
26551456 26551479 1 + 27013184 SW480 treatment with recombinant TRAIL TTCGTGGTGAAGCTGCACTATGG RPS6KA1 ENSG00000117676 0.5426024115471685 [211,209] [116,154] 2 hSpCas9 positive selection 2958376
26551456 26551479 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL TTCGTGGTGAAGCTGCACTATGG RPS6KA1 ENSG00000281877 0.5426024115471685 [211,209] [116,154] 2 hSpCas9 positive selection 2958377
26547258 26547281 1 + 27013184 SW480 treatment with recombinant TRAIL GCAACGCTGAAAGGTGAGTGGGG RPS6KA1 ENSG00000117676 1.8981089130839794 [189,179] [230,393] 8 hSpCas9 positive selection 2958378
26547258 26547281 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL GCAACGCTGAAAGGTGAGTGGGG RPS6KA1 ENSG00000281877 1.8981089130839794 [189,179] [230,393] 8 hSpCas9 positive selection 2958379
26551434 26551457 CHR_HG2058_PATCH - 27013184 SW480 treatment with recombinant TRAIL ATGGGTGATTTACATCAGCCAGG RPS6KA1 ENSG00000281877 0.6159825017374486 [360,260] [220,190] 3 hSpCas9 positive selection 2958380
26551434 26551457 1 - 27013184 SW480 treatment with recombinant TRAIL ATGGGTGATTTACATCAGCCAGG RPS6KA1 ENSG00000117676 0.6159825017374486 [360,260] [220,190] 3 hSpCas9 positive selection 2958381
26551452 26551475 CHR_HG2058_PATCH - 27013184 SW480 treatment with recombinant TRAIL AGTGCAGCTTCACCACGAATGGG RPS6KA1 ENSG00000281877 -0.36488602440240586 [117,243] [26,103] -2 hSpCas9 positive selection 2958382
26551452 26551475 1 - 27013184 SW480 treatment with recombinant TRAIL AGTGCAGCTTCACCACGAATGGG RPS6KA1 ENSG00000117676 -0.36488602440240586 [117,243] [26,103] -2 hSpCas9 positive selection 2958383
26551453 26551476 1 - 27013184 SW480 treatment with recombinant TRAIL TAGTGCAGCTTCACCACGAATGG RPS6KA1 ENSG00000117676 0.3035609984951451 [176,166] [83,102] 1 hSpCas9 positive selection 2958384
26551453 26551476 CHR_HG2058_PATCH - 27013184 SW480 treatment with recombinant TRAIL TAGTGCAGCTTCACCACGAATGG RPS6KA1 ENSG00000281877 0.3035609984951451 [176,166] [83,102] 1 hSpCas9 positive selection 2958385
26529928 26529951 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL TCGCCCAGCTCAAGGAGCCCTGG RPS6KA1 ENSG00000281877 -0.550504972435991 [1325,2061] [297,761] -2 hSpCas9 positive selection 2958386
26529928 26529951 1 + 27013184 SW480 treatment with recombinant TRAIL TCGCCCAGCTCAAGGAGCCCTGG RPS6KA1 ENSG00000117676 -0.550504972435991 [1325,2061] [297,761] -2 hSpCas9 positive selection 2958387
26551468 26551491 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL CTGCACTATGGTAAAGCTTCTGG RPS6KA1 ENSG00000281877 0.9149969907921447 [177,198] [164,134] 4 hSpCas9 positive selection 2958388
26551468 26551491 1 + 27013184 SW480 treatment with recombinant TRAIL CTGCACTATGGTAAAGCTTCTGG RPS6KA1 ENSG00000117676 0.9149969907921447 [177,198] [164,134] 4 hSpCas9 positive selection 2958389
26529938 26529961 1 + 27013184 SW480 treatment with recombinant TRAIL CAAGGAGCCCTGGCCGCTCATGG RPS6KA1 ENSG00000117676 1.271165371527494 [170,211] [107,324] 6 hSpCas9 positive selection 2958390
26529938 26529961 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL CAAGGAGCCCTGGCCGCTCATGG RPS6KA1 ENSG00000281877 1.271165371527494 [170,211] [107,324] 6 hSpCas9 positive selection 2958391
26546878 26546901 CHR_HG2058_PATCH - 27013184 SW480 treatment with recombinant TRAIL GCGTGATGGAGATCTCCTTGAGG RPS6KA1 ENSG00000281877 1.3502482266676834 [109,91] [59,185] 6 hSpCas9 positive selection 2958392
26546878 26546901 1 - 27013184 SW480 treatment with recombinant TRAIL GCGTGATGGAGATCTCCTTGAGG RPS6KA1 ENSG00000117676 1.3502482266676834 [109,91] [59,185] 6 hSpCas9 positive selection 2958393
26546892 26546915 CHR_HG2058_PATCH - 27013184 SW480 treatment with recombinant TRAIL AGCCTTGACGTGGTGCGTGATGG RPS6KA1 ENSG00000281877 2.855022283138553 [192,420] [1020,792] 9 hSpCas9 positive selection 2958394
26546892 26546915 1 - 27013184 SW480 treatment with recombinant TRAIL AGCCTTGACGTGGTGCGTGATGG RPS6KA1 ENSG00000117676 2.855022283138553 [192,420] [1020,792] 9 hSpCas9 positive selection 2958395
26546902 26546925 CHR_HG2058_PATCH - 27013184 SW480 treatment with recombinant TRAIL TCTCAGAGCCAGCCTTGACGTGG RPS6KA1 ENSG00000281877 -0.1461529228658216 [526,843] [312,188] 0 hSpCas9 positive selection 2958396
26546902 26546925 1 - 27013184 SW480 treatment with recombinant TRAIL TCTCAGAGCCAGCCTTGACGTGG RPS6KA1 ENSG00000117676 -0.1461529228658216 [526,843] [312,188] 0 hSpCas9 positive selection 2958397
26546950 26546973 1 - 27013184 SW480 treatment with recombinant TRAIL ATCCCTGGCCCAGAACCTTGAGG RPS6KA1 ENSG00000117676 1.5983005688971856 [663,907] [848,1245] 7 hSpCas9 positive selection 2958398
26546950 26546973 CHR_HG2058_PATCH - 27013184 SW480 treatment with recombinant TRAIL ATCCCTGGCCCAGAACCTTGAGG RPS6KA1 ENSG00000281877 1.5983005688971856 [663,907] [848,1245] 7 hSpCas9 positive selection 2958399
26529953 26529976 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL GCTCATGGAGCTAGTGCCTCTGG RPS6KA1 ENSG00000281877 -1.880151344598873 [673,630] [98,44] -7 hSpCas9 positive selection 2958400
26529953 26529976 1 + 27013184 SW480 treatment with recombinant TRAIL GCTCATGGAGCTAGTGCCTCTGG RPS6KA1 ENSG00000117676 -1.880151344598873 [673,630] [98,44] -7 hSpCas9 positive selection 2958401
26546965 26546988 CHR_HG2058_PATCH - 27013184 SW480 treatment with recombinant TRAIL TCACTTTGCCAAAGGATCCCTGG RPS6KA1 ENSG00000281877 -0.46361751741700363 [87,192] [25,65] -2 hSpCas9 positive selection 2958402
26546965 26546988 1 - 27013184 SW480 treatment with recombinant TRAIL TCACTTTGCCAAAGGATCCCTGG RPS6KA1 ENSG00000117676 -0.46361751741700363 [87,192] [25,65] -2 hSpCas9 positive selection 2958403
26546973 26546996 1 - 27013184 SW480 treatment with recombinant TRAIL CTCATGACTCACTTTGCCAAAGG RPS6KA1 ENSG00000117676 1.1817717958679421 [34,8] [13,34] 5 hSpCas9 positive selection 2958404
26546973 26546996 CHR_HG2058_PATCH - 27013184 SW480 treatment with recombinant TRAIL CTCATGACTCACTTTGCCAAAGG RPS6KA1 ENSG00000281877 1.1817717958679421 [34,8] [13,34] 5 hSpCas9 positive selection 2958405
26547230 26547253 CHR_HG2058_PATCH - 27013184 SW480 treatment with recombinant TRAIL TCAGCACCTTCATAGCATACAGG RPS6KA1 ENSG00000281877 0.9352787948051258 [251,123] [184,123] 4 hSpCas9 positive selection 2958406
26547230 26547253 1 - 27013184 SW480 treatment with recombinant TRAIL TCAGCACCTTCATAGCATACAGG RPS6KA1 ENSG00000117676 0.9352787948051258 [251,123] [184,123] 4 hSpCas9 positive selection 2958407
26529959 26529982 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL GGAGCTAGTGCCTCTGGACCCGG RPS6KA1 ENSG00000281877 -0.6404812699790383 [447,412] [112,128] -3 hSpCas9 positive selection 2958408
26529959 26529982 1 + 27013184 SW480 treatment with recombinant TRAIL GGAGCTAGTGCCTCTGGACCCGG RPS6KA1 ENSG00000117676 -0.6404812699790383 [447,412] [112,128] -3 hSpCas9 positive selection 2958409
26529962 26529985 CHR_HG2058_PATCH + 27013184 SW480 treatment with recombinant TRAIL GCTAGTGCCTCTGGACCCGGAGG RPS6KA1 ENSG00000281877 1.7648342369049836 [227,544] [605,460] 7 hSpCas9 positive selection 2958410
26529962 26529985 1 + 27013184 SW480 treatment with recombinant TRAIL GCTAGTGCCTCTGGACCCGGAGG RPS6KA1 ENSG00000117676 1.7648342369049836 [227,544] [605,460] 7 hSpCas9 positive selection 2958411
26551653 26551676 1 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 0.14061637916055997 [4,5] [6,3] 3 hSpCas9 positive selection 3017970
26557006 26557029 1 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 0.180564232146734 [3,4] [2,4] 4 hSpCas9 positive selection 3017971
26555600 26555623 1 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity TCAAGCGGAATCCTGCCAACCGG RPS6KA1 ENSG00000117676 -0.06439781318569363 [2,3] [2,2] -1 hSpCas9 positive selection 3017972
26553385 26553408 1 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 -0.25287481840185927 [2,3] [2,1] -4 hSpCas9 positive selection 3017973
26551653 26551676 1 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 0.312720272941447 [4,4] [4,3] 5 hSpCas9 positive selection 3085828
26557006 26557029 1 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 -0.09388869289733398 [3,3] [3,1] -1 hSpCas9 positive selection 3085829
26555600 26555623 1 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity TCAAGCGGAATCCTGCCAACCGG RPS6KA1 ENSG00000117676 0.005334942145720306 [2,2] [2,0] 0 hSpCas9 positive selection 3085830
26553385 26553408 1 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.7074293660960771 [2,2] [5,2] 9 hSpCas9 positive selection 3085831
26553453 26553476 - 24336571 A375 resistance to PLX after 7 days AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.15255541382000642 [18,14] [19,17] 5 hSpCas9 positive selection 3141880
26536935 26536958 - 24336571 A375 resistance to PLX after 7 days AAGTCCAGCTTCTTCCCCTGAGG RPS6KA1 ENSG00000117676 0.04173972794892056 [23,20] [20,23] 1 hSpCas9 positive selection 3141881
26551653 26551676 - 24336571 A375 resistance to PLX after 7 days AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 0.12019082400087333 [31,27] [32,30] 4 hSpCas9 positive selection 3141882
26536948 26536971 + 24336571 A375 resistance to PLX after 7 days AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.23857775120013974 [12,15] [16,16] 7 hSpCas9 positive selection 3141883
26553444 26553467 + 24336571 A375 resistance to PLX after 7 days CCTGGATCACCTGCACAGCCTGG RPS6KA1 ENSG00000117676 0.6023619072061607 [7,6] [9,13] 9 hSpCas9 positive selection 3141884
26551670 26551693 + 24336571 A375 resistance to PLX after 7 days CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.03198112423523547 [25,31] [30,28] 1 hSpCas9 positive selection 3141885
26553405 26553428 + 24336571 A375 resistance to PLX after 7 days GGAGGATGTGAAGTTTTACCTGG RPS6KA1 ENSG00000117676 0.37837858024437565 [5,4] [7,6] 8 hSpCas9 positive selection 3141886
26551684 26551707 - 24336571 A375 resistance to PLX after 7 days TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.022421439692986933 [29,23] [26,28] 0 hSpCas9 positive selection 3141887
26536919 26536942 + 24336571 A375 resistance to PLX after 7 days TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.33227944253044606 [22,21] [26,28] 8 hSpCas9 positive selection 3141888
26553453 26553476 - 24336571 A375 resistance to PLX after 14 days AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 1.1410194540919898 [16,15] [14,18] 8 hSpCas9 positive selection 3199673
26536935 26536958 - 24336571 A375 resistance to PLX after 14 days AAGTCCAGCTTCTTCCCCTGAGG RPS6KA1 ENSG00000117676 -1.0188730130642674 [23,25] [5,4] -9 hSpCas9 positive selection 3199674
26551653 26551676 - 24336571 A375 resistance to PLX after 14 days AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 -0.1630325021426342 [29,16] [9,8] -2 hSpCas9 positive selection 3199675
26536948 26536971 + 24336571 A375 resistance to PLX after 14 days AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 -0.0149459583329824 [8,22] [7,5] 0 hSpCas9 positive selection 3199676
26553444 26553467 + 24336571 A375 resistance to PLX after 14 days CCTGGATCACCTGCACAGCCTGG RPS6KA1 ENSG00000117676 -0.04927406139078197 [12,9] [4,4] 0 hSpCas9 positive selection 3199677
26551670 26551693 + 24336571 A375 resistance to PLX after 14 days CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.20807696525413166 [24,30] [14,13] 2 hSpCas9 positive selection 3199678
26553405 26553428 + 24336571 A375 resistance to PLX after 14 days GGAGGATGTGAAGTTTTACCTGG RPS6KA1 ENSG00000117676 0.8809593635860561 [4,4] [3,4] 7 hSpCas9 positive selection 3199679
26551684 26551707 - 24336571 A375 resistance to PLX after 14 days TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 1.092040928991593 [22,20] [23,19] 8 hSpCas9 positive selection 3199680
26536919 26536942 + 24336571 A375 resistance to PLX after 14 days TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.4406640232923107 [34,21] [7,10] -5 hSpCas9 positive selection 3199681
26553453 26553476 - 24336571 A375 viability after 7 days AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.46503068282297594 [12] [18,14] 7 hSpCas9 negative selection 3257466
26536935 26536958 - 24336571 A375 viability after 7 days AAGTCCAGCTTCTTCCCCTGAGG RPS6KA1 ENSG00000117676 0.019000904562819554 [22] [23,20] 0 hSpCas9 negative selection 3257467
26551653 26551676 - 24336571 A375 viability after 7 days AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 -0.09024031096384966 [32] [31,27] -1 hSpCas9 negative selection 3257468
26536948 26536971 + 24336571 A375 viability after 7 days AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.7284364489510939 [8] [12,15] 9 hSpCas9 negative selection 3257469
26553444 26553467 + 24336571 A375 viability after 7 days CCTGGATCACCTGCACAGCCTGG RPS6KA1 ENSG00000117676 -0.11621365730321698 [8] [7,6] -2 hSpCas9 negative selection 3257470
26551670 26551693 + 24336571 A375 viability after 7 days CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.236062129085576 [25] [25,31] 3 hSpCas9 negative selection 3257471
26553405 26553428 + 24336571 A375 viability after 7 days GGAGGATGTGAAGTTTTACCTGG RPS6KA1 ENSG00000117676 0.08737235523529963 [4] [5,4] 1 hSpCas9 negative selection 3257472
26551684 26551707 - 24336571 A375 viability after 7 days TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.042947623207579166 [27] [29,23] 0 hSpCas9 negative selection 3257473
26536919 26536942 + 24336571 A375 viability after 7 days TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.6845937898994 [13] [22,21] 8 hSpCas9 negative selection 3257474
26553453 26553476 - 24336571 A375 viability after 14 days AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.4616389529107961 [12] [16,15] 6 hSpCas9 negative selection 3315259
26536935 26536958 - 24336571 A375 viability after 14 days AAGTCCAGCTTCTTCCCCTGAGG RPS6KA1 ENSG00000117676 0.19246735767278567 [22] [23,25] 2 hSpCas9 negative selection 3315260
26551653 26551676 - 24336571 A375 viability after 14 days AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 -0.3956513938695858 [32] [29,16] -5 hSpCas9 negative selection 3315261
26536948 26536971 + 24336571 A375 viability after 14 days AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.9070557527200375 [8] [8,22] 9 hSpCas9 negative selection 3315262
26553444 26553467 + 24336571 A375 viability after 14 days CCTGGATCACCTGCACAGCCTGG RPS6KA1 ENSG00000117676 0.3832458601151254 [8] [12,9] 5 hSpCas9 negative selection 3315263
26551670 26551693 + 24336571 A375 viability after 14 days CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.1877593417994563 [25] [24,30] 2 hSpCas9 negative selection 3315264
26553405 26553428 + 24336571 A375 viability after 14 days GGAGGATGTGAAGTTTTACCTGG RPS6KA1 ENSG00000117676 -0.021195939320881374 [4] [4,4] 0 hSpCas9 negative selection 3315265
26551684 26551707 - 24336571 A375 viability after 14 days TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 -0.2475899846723577 [27] [22,20] -3 hSpCas9 negative selection 3315266
26536919 26536942 + 24336571 A375 viability after 14 days TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 1.064898289639782 [13] [34,21] 9 hSpCas9 negative selection 3315267
26536919 26536942 1 + 27383988 293T resistance to West Nile virus (flavivirus) TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.6253168379160062 [235,235] [0,0] -4 hSpCas9 positive selection 3390664
26553453 26553476 1 - 27383988 293T resistance to West Nile virus (flavivirus) AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.4499712893882311 [111,111] [0,0] 2 hSpCas9 positive selection 3390665
26553483 26553506 1 - 27383988 293T resistance to West Nile virus (flavivirus) TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 -1.3201026165899135 [381,381] [0,0] -8 hSpCas9 positive selection 3390666
26551653 26551676 1 - 26780180 HT29 viability (Avana library 4 designs) AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 0.643832488617485 [] [] 2 hSpCas9 negative selection 3456351
26557006 26557029 1 - 26780180 HT29 viability (Avana library 4 designs) AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 1.33231561318445 [] [] 5 hSpCas9 negative selection 3456352
26555599 26555622 1 + 26780180 HT29 viability (Avana library 4 designs) TCAAGCGGAATCCTGCCAACCGG RPS6KA1 ENSG00000117676 0.590205349591389 [] [] 2 hSpCas9 negative selection 3456353
26553384 26553407 1 + 26780180 HT29 viability (Avana library 4 designs) TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.107418056645131 [] [] 0 hSpCas9 negative selection 3456354
26553384 26553407 1 + 26780180 A375 viability (Avana lentiCRISPRv2) TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 2.72503560159247 [] [] 4 hSpCas9 negative selection 3554786
26551653 26551676 1 - 26780180 A375 viability (Avana lentiCRISPRv2) AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 1.67498394101622 [] [] 2 hSpCas9 negative selection 3554787
26557006 26557029 1 - 26780180 A375 viability (Avana lentiCRISPRv2) AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 1.13175255493492 [] [] 1 hSpCas9 negative selection 3554788
26555599 26555622 1 + 26780180 A375 viability (Avana lentiCRISPRv2) TCAAGCGGAATCCTGCCAACCGG RPS6KA1 ENSG00000117676 -0.236314968410423 [] [] 0 hSpCas9 negative selection 3554789
26529962 26529985 1 + 26780180 A375 viability (Avana lentiCRISPRv2) GCTAGTGCCTCTGGACCCGGAGG RPS6KA1 ENSG00000117676 7.54545598639601 [] [] 9 hSpCas9 negative selection 3554790
26555553 26555576 1 - 26780180 A375 viability (Avana lentiCRISPRv2) GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 3.95692444630481 [] [] 6 hSpCas9 negative selection 3554791
26553384 26553407 1 + 26780180 A375 viability (Avana lentiGuide) TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 1.49692626729861 [] [] 1 hSpCas9 negative selection 3663445
26551653 26551676 1 - 26780180 A375 viability (Avana lentiGuide) AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 3.83256543495787 [] [] 4 hSpCas9 negative selection 3663446
26557006 26557029 1 - 26780180 A375 viability (Avana lentiGuide) AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 6.19872559631665 [] [] 5 hSpCas9 negative selection 3663447
26555599 26555622 1 + 26780180 A375 viability (Avana lentiGuide) TCAAGCGGAATCCTGCCAACCGG RPS6KA1 ENSG00000117676 -1.76829847268553 [] [] -3 hSpCas9 negative selection 3663448
26529962 26529985 1 + 26780180 A375 viability (Avana lentiGuide) GCTAGTGCCTCTGGACCCGGAGG RPS6KA1 ENSG00000117676 -9.22964625510551 [] [] -9 hSpCas9 negative selection 3663449
26555553 26555576 1 - 26780180 A375 viability (Avana lentiGuide) GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 3.94414882922355 [] [] 4 hSpCas9 negative selection 3663450
26553384 26553407 1 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.11124571965020195 [4] [5,4] 3 hSpCas9 positive selection 3772052
26551653 26551676 1 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 0.016204947768117428 [6] [7,5] 0 hSpCas9 positive selection 3772053
26557006 26557029 1 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 0.14214819726972952 [5] [6,5] 4 hSpCas9 positive selection 3772054
26555599 26555622 1 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TCAAGCGGAATCCTGCCAACCGG RPS6KA1 ENSG00000117676 0.14259490691769916 [4] [4,4] 4 hSpCas9 positive selection 3772055
26529962 26529985 1 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCTAGTGCCTCTGGACCCGGAGG RPS6KA1 ENSG00000117676 0.5428589604966759 [2] [4,4] 9 hSpCas9 positive selection 3772056
26555553 26555576 1 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 0.08440490789323235 [4] [4,4] 2 hSpCas9 positive selection 3772057
26553384 26553407 1 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 -0.188940345120589 [5] [3,4] -3 hSpCas9 positive selection 3880659
26551653 26551676 1 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 0.006331076725837825 [7] [7,5] 0 hSpCas9 positive selection 3880660
26557006 26557029 1 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 -0.16716044031498092 [5] [4,4] -2 hSpCas9 positive selection 3880661
26555599 26555622 1 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TCAAGCGGAATCCTGCCAACCGG RPS6KA1 ENSG00000117676 0.3340964103341265 [4] [4,5] 8 hSpCas9 positive selection 3880662
26529962 26529985 1 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCTAGTGCCTCTGGACCCGGAGG RPS6KA1 ENSG00000117676 0.5512225064213044 [2] [3,2] 9 hSpCas9 positive selection 3880663
26555553 26555576 1 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 0.2545934907267151 [5] [5,5] 6 hSpCas9 positive selection 3880664
26553453 26553476 1 - 26780180 A375 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 1.58274497007935 [] [] 8 hSpCas9 negative selection 3990683
26536948 26536971 1 + 26780180 A375 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 1.17560633777569 [] [] 6 hSpCas9 negative selection 3990684
26551670 26551693 1 + 26780180 A375 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 1.40675700167934 [] [] 7 hSpCas9 negative selection 3990685
26553483 26553506 1 - 26780180 A375 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.0694024550332381 [] [] 0 hSpCas9 negative selection 3990686
26551684 26551707 1 - 26780180 A375 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 2.14563182165697 [] [] 9 hSpCas9 negative selection 3990687
26536919 26536942 1 + 26780180 A375 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 1.03712203872919 [] [] 5 hSpCas9 negative selection 3990688
26553453 26553476 1 - 26780180 HT29 viability (GeCKOv2 library) AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 1.52513436964563 [] [] 7 hSpCas9 negative selection 4098649
26536948 26536971 1 + 26780180 HT29 viability (GeCKOv2 library) AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.741129446497587 [] [] 3 hSpCas9 negative selection 4098650
26551670 26551693 1 + 26780180 HT29 viability (GeCKOv2 library) CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 1.33265460000782 [] [] 6 hSpCas9 negative selection 4098651
26553483 26553506 1 - 26780180 HT29 viability (GeCKOv2 library) TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.375678366311574 [] [] 1 hSpCas9 negative selection 4098652
26551684 26551707 1 - 26780180 HT29 viability (GeCKOv2 library) TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 3.05081105787955 [] [] 9 hSpCas9 negative selection 4098653
26536919 26536942 1 + 26780180 HT29 viability (GeCKOv2 library) TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 1.15970365479842 [] [] 5 hSpCas9 negative selection 4098654
26553453 26553476 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.31297409438558577 [3] [2,4] 7 hSpCas9 positive selection 4167566
26536935 26536958 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) AAGTCCAGCTTCTTCCCCTGAGG RPS6KA1 ENSG00000117676 -0.1002236820517334 [4] [3,2] -2 hSpCas9 positive selection 4167567
26551653 26551676 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 0.01603528963285472 [5] [3,3] 0 hSpCas9 positive selection 4167568
26536948 26536971 1 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.1586713598936769 [3] [2,2] 4 hSpCas9 positive selection 4167569
26553444 26553467 1 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CCTGGATCACCTGCACAGCCTGG RPS6KA1 ENSG00000117676 0.755768482540393 [3] [6,2] 9 hSpCas9 positive selection 4167570
26551670 26551693 1 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.1251539379019081 [5] [3,3] 3 hSpCas9 positive selection 4167571
26553405 26553428 1 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GGAGGATGTGAAGTTTTACCTGG RPS6KA1 ENSG00000117676 -0.09850135856506015 [2] [1,1] -2 hSpCas9 positive selection 4167572
26551684 26551707 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.2958189017773834 [4] [3,4] 7 hSpCas9 positive selection 4167573
26536919 26536942 1 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.019315010649494563 [3] [1,3] 0 hSpCas9 positive selection 4167575
26553453 26553476 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.4073929917893184 [3] [0,0,1,0] -6 hSpCas9 positive selection 4231588
26536935 26536958 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) AAGTCCAGCTTCTTCCCCTGAGG RPS6KA1 ENSG00000117676 1.0121995077532915 [3] [0,0,5,3] 7 hSpCas9 positive selection 4231589
26551653 26551676 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) AATGAGATAGAGCTTGCCCTCGG RPS6KA1 ENSG00000117676 0.2426759067930359 [5] [4,3,5,0] 2 hSpCas9 positive selection 4231590
26536948 26536971 1 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 -0.1830215521683355 [3] [0,0,2,0] -3 hSpCas9 positive selection 4231591
26553444 26553467 1 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CCTGGATCACCTGCACAGCCTGG RPS6KA1 ENSG00000117676 0.1454445885833633 [3] [0,2,3,0] 1 hSpCas9 positive selection 4231592
26551670 26551693 1 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 1.4560652349554224 [3] [2,4,5,5] 9 hSpCas9 positive selection 4231593
26553405 26553428 1 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GGAGGATGTGAAGTTTTACCTGG RPS6KA1 ENSG00000117676 0.18632345516006754 [2] [1,0,1,0] 1 hSpCas9 positive selection 4231594
26551684 26551707 1 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 1.1436645463454707 [4] [3,3,4,3] 8 hSpCas9 positive selection 4231595
26536919 26536942 1 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 1.220007198104012 [2] [4,2,0,3] 8 hSpCas9 positive selection 4231597
26551684 26551707 1 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 -1.355294308719 [2] [0,0] -9 hSpCas9 positive selection 4295789
26536948 26536971 1 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.017635120536273488 [3] [3,1] 0 hSpCas9 positive selection 4295790
26551670 26551693 1 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.27240061080900746 [2] [2,2] 5 hSpCas9 positive selection 4295791
26536919 26536942 1 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.19926324993451539 [3] [3,1] -4 hSpCas9 positive selection 4360042
26553453 26553476 1 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.1026021275500813 [2] [2,0] -2 hSpCas9 positive selection 4360043
26553483 26553506 1 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.4720119971689699 [3] [4,4] 8 hSpCas9 positive selection 4360044
26555614 26555636 1 - 27760321 OCIAML3 viability GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 -1.9294411219451202 [420,325] [53,104] -9 hSpCas9 negative selection 4435943
26546895 26546917 1 + 27760321 OCIAML3 viability TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -1.0809858249246593 [586,463] [222,153] -7 hSpCas9 negative selection 4435944
26551393 26551415 1 - 27760321 OCIAML3 viability TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 -2.7068887378975672 [394,356] [44,44] -9 hSpCas9 negative selection 4435945
26551648 26551670 1 - 27760321 OCIAML3 viability ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 -2.0152563411393603 [766,619] [109,163] -9 hSpCas9 negative selection 4435946
26554674 26554696 1 + 27760321 OCIAML3 viability CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 -1.0295862972052823 [659,569] [214,260] -7 hSpCas9 negative selection 4435947
26555614 26555636 1 - 27760321 OCIAML2 viability GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 -1.1838113821235672 [420,325] [103,168] -8 hSpCas9 negative selection 4519406
26546895 26546917 1 + 27760321 OCIAML2 viability TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.7705193612535199 [586,463] [197,312] -7 hSpCas9 negative selection 4519407
26551393 26551415 1 - 27760321 OCIAML2 viability TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 -1.1797460253642538 [394,356] [90,190] -8 hSpCas9 negative selection 4519408
26551648 26551670 1 - 27760321 OCIAML2 viability ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 -1.7512608655343673 [766,619] [119,225] -9 hSpCas9 negative selection 4519409
26554674 26554696 1 + 27760321 OCIAML2 viability CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 -1.5835156267785497 [659,569] [105,243] -8 hSpCas9 negative selection 4519410
26555614 26555636 1 - 27760321 MV411 viability GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 -0.47720790481806347 [420,325] [164,191] -3 hSpCas9 negative selection 4602869
26546895 26546917 1 + 27760321 MV411 viability TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.17562869189738983 [586,463] [171,504] -1 hSpCas9 negative selection 4602870
26551393 26551415 1 - 27760321 MV411 viability TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 -1.1494947777172515 [394,356] [54,196] -6 hSpCas9 negative selection 4602871
26551648 26551670 1 - 27760321 MV411 viability ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 -0.2094141153421752 [766,619] [230,637] -1 hSpCas9 negative selection 4602872
26554674 26554696 1 + 27760321 MV411 viability CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 0.24492751979249416 [659,569] [507,436] 1 hSpCas9 negative selection 4602873
26555614 26555636 1 - 27760321 HL60 viability GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 -1.927750514768478 [420,325] [66,92] -9 hSpCas9 negative selection 4686332
26546895 26546917 1 + 27760321 HL60 viability TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.7019212143113955 [586,463] [219,306] -6 hSpCas9 negative selection 4686333
26551393 26551415 1 - 27760321 HL60 viability TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 -0.549330225982642 [394,356] [116,307] -5 hSpCas9 negative selection 4686334
26551648 26551670 1 - 27760321 HL60 viability ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 -1.656993520460954 [766,619] [150,207] -9 hSpCas9 negative selection 4686335
26554674 26554696 1 + 27760321 HL60 viability CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 -0.508498218060751 [659,569] [374,327] -5 hSpCas9 negative selection 4686336
26555614 26555636 1 - 27760321 HT1080 viability GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 1.5679620103086505 [325,254] [472,200] 8 hSpCas9 negative selection 4769795
26546895 26546917 1 + 27760321 HT1080 viability TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.2648714342530471 [463,361] [211,181] 1 hSpCas9 negative selection 4769796
26551393 26551415 1 - 27760321 HT1080 viability TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 -0.29235471598094565 [356,278] [112,92] -1 hSpCas9 negative selection 4769797
26551648 26551670 1 - 27760321 HT1080 viability ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 -2.5386329592514754 [619,483] [2,75] -7 hSpCas9 negative selection 4769798
26554674 26554696 1 + 27760321 HT1080 viability CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 -0.5262469508418554 [569,444] [158,119] -2 hSpCas9 negative selection 4769799
26555614 26555636 1 - 27760321 HT29 viability after 7 days GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 -0.0894234123381486 [325,254] [540,191,346] -1 hSpCas9 negative selection 4853258
26546895 26546917 1 + 27760321 HT29 viability after 7 days TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.24687421114208147 [463,361] [671,582,639] 4 hSpCas9 negative selection 4853259
26551393 26551415 1 - 27760321 HT29 viability after 7 days TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 0.3664315628603433 [356,278] [578,576,434] 5 hSpCas9 negative selection 4853260
26551648 26551670 1 - 27760321 HT29 viability after 7 days ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 0.5299425538362762 [619,483] [1238,1083,787] 7 hSpCas9 negative selection 4853261
26554674 26554696 1 + 27760321 HT29 viability after 7 days CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 0.11982926027531715 [569,444] [931,839,395] 1 hSpCas9 negative selection 4853262
26555614 26555636 1 - 27760321 HT29 viability after 25 days GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 0.3552796641760081 [325,254] [472,394,399] 4 hSpCas9 negative selection 4936721
26546895 26546917 1 + 27760321 HT29 viability after 25 days TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.4429484383831656 [463,361] [575,683,670] 5 hSpCas9 negative selection 4936722
26551393 26551415 1 - 27760321 HT29 viability after 25 days TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 0.6927264638796475 [356,278] [598,416,762] 7 hSpCas9 negative selection 4936723
26551648 26551670 1 - 27760321 HT29 viability after 25 days ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 0.5139092833524442 [619,483] [775,763,1199] 5 hSpCas9 negative selection 4936724
26554674 26554696 1 + 27760321 HT29 viability after 25 days CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 0.7134859332164494 [569,444] [931,994,922] 7 hSpCas9 negative selection 4936725
26555614 26555636 1 - 27760321 HT29 viability after 22 days GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 0.39407607255963945 [325,254] [523,448,347] 4 hSpCas9 negative selection 5020184
26546895 26546917 1 + 27760321 HT29 viability after 22 days TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.5627744146827938 [463,361] [926,545,635] 6 hSpCas9 negative selection 5020185
26551393 26551415 1 - 27760321 HT29 viability after 22 days TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 0.5711792988670988 [356,278] [529,471,637] 6 hSpCas9 negative selection 5020186
26551648 26551670 1 - 27760321 HT29 viability after 22 days ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 0.5149456403417475 [619,483] [782,633,1325] 5 hSpCas9 negative selection 5020187
26554674 26554696 1 + 27760321 HT29 viability after 22 days CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 0.555900002396283 [569,444] [840,891,854] 6 hSpCas9 negative selection 5020188
26555614 26555636 1 - 27760321 HT29 viability after 19 days GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 0.8193091614350221 [325,254] [636,676,454] 8 hSpCas9 negative selection 5103647
26546895 26546917 1 + 27760321 HT29 viability after 19 days TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.5883881457073203 [463,361] [864,617,664] 6 hSpCas9 negative selection 5103648
26551393 26551415 1 - 27760321 HT29 viability after 19 days TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 0.5836808432697107 [356,278] [435,521,660] 6 hSpCas9 negative selection 5103649
26551648 26551670 1 - 27760321 HT29 viability after 19 days ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 0.6452797455424747 [619,483] [1292,1046,665] 6 hSpCas9 negative selection 5103650
26554674 26554696 1 + 27760321 HT29 viability after 19 days CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 0.633116047963598 [569,444] [1080,713,922] 6 hSpCas9 negative selection 5103651
26555614 26555636 1 - 27760321 HT29 viability after 16 days GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 0.4282754993628818 [325,254] [505,537,271] 5 hSpCas9 negative selection 5187110
26546895 26546917 1 + 27760321 HT29 viability after 16 days TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.20108726870459498 [463,361] [381,657,535] 2 hSpCas9 negative selection 5187111
26551393 26551415 1 - 27760321 HT29 viability after 16 days TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 0.36103461241165613 [356,278] [574,342,466] 4 hSpCas9 negative selection 5187112
26551648 26551670 1 - 27760321 HT29 viability after 16 days ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 0.7515652344310463 [619,483] [1533,651,989] 8 hSpCas9 negative selection 5187113
26554674 26554696 1 + 27760321 HT29 viability after 16 days CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 0.5139043490948592 [569,444] [804,911,711] 6 hSpCas9 negative selection 5187114
26555614 26555636 1 - 27760321 HT29 viability after 13 days GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 0.41774925035454913 [325,254] [478,444,427] 5 hSpCas9 negative selection 5270573
26546895 26546917 1 + 27760321 HT29 viability after 13 days TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.15619952545696675 [463,361] [551,386,654] 2 hSpCas9 negative selection 5270574
26551393 26551415 1 - 27760321 HT29 viability after 13 days TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 0.13984118099753387 [356,278] [359,392,462] 1 hSpCas9 negative selection 5270575
26551648 26551670 1 - 27760321 HT29 viability after 13 days ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 0.5797795223345074 [619,483] [1029,899,941] 7 hSpCas9 negative selection 5270576
26554674 26554696 1 + 27760321 HT29 viability after 13 days CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 0.5169283277467798 [569,444] [995,911,631] 6 hSpCas9 negative selection 5270577
26555614 26555636 1 - 27760321 HT29 viability after 10 days GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 0.46772674224884975 [325,254] [472,395,629] 6 hSpCas9 negative selection 5354036
26546895 26546917 1 + 27760321 HT29 viability after 10 days TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.14722435500826297 [463,361] [539,496,362] -2 hSpCas9 negative selection 5354037
26551393 26551415 1 - 27760321 HT29 viability after 10 days TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 0.34172676114915734 [356,278] [481,361,657] 4 hSpCas9 negative selection 5354038
26551648 26551670 1 - 27760321 HT29 viability after 10 days ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 0.05863189272555713 [619,483] [764,650,734] 0 hSpCas9 negative selection 5354039
26554674 26554696 1 + 27760321 HT29 viability after 10 days CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 0.04820368101765404 [569,444] [753,541,665] 0 hSpCas9 negative selection 5354040
26555614 26555636 1 - 27760321 MOLM13 viability GGCTGCTTACCGAGCCGGTTGG RPS6KA1 ENSG00000117676 -3.1693985792265362 [420,325] [39,8] -9 hSpCas9 negative selection 5437499
26546895 26546917 1 + 27760321 MOLM13 viability TCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -1.5665312701055316 [586,463] [146,58] -7 hSpCas9 negative selection 5437500
26551393 26551415 1 - 27760321 MOLM13 viability TCCGGACGCGGTCACGTACTGG RPS6KA1 ENSG00000117676 -0.4935633593548332 [394,356] [1,276] -3 hSpCas9 negative selection 5437501
26551648 26551670 1 - 27760321 MOLM13 viability ATAGAGCTTGCCCTCGGTCTGG RPS6KA1 ENSG00000117676 -1.5508830438618881 [766,619] [141,124] -7 hSpCas9 negative selection 5437502
26554674 26554696 1 + 27760321 MOLM13 viability CTGAGGTCGTCAACCGCCAGGG RPS6KA1 ENSG00000117676 -1.0675920796737186 [659,569] [304,45] -6 hSpCas9 negative selection 5437503
26529802 26529825 1 + 27661255 K562 viability GGAGCGCGAGGGGCTCGGGGGGG RPS6KA1 ENSG00000117676 -1.095591689086615 [387,573] [177,178] -8 dCas9-KRAB negative selection 5508617
26530021 26530044 1 + 27661255 K562 viability GCGAGCCCGGATCCTCACAGGGG RPS6KA1 ENSG00000117676 -0.21585499650614215 [423,491] [365,269] -6 dCas9-KRAB negative selection 5508618
26546235 26546258 1 + 27661255 K562 viability GGGAGGGTAGAGTCCTGGAAAGG RPS6KA1 ENSG00000117676 0.06686083227550599 [953,1235] [1135,720] 2 dCas9-KRAB negative selection 5508619
26546246 26546269 1 + 27661255 K562 viability GTCCTGGAAAGGCTAGGACCTGG RPS6KA1 ENSG00000117676 0.33967575758860047 [366,430] [426,380] 9 dCas9-KRAB negative selection 5508620
26530179 26530202 1 - 27661255 K562 viability GGCTATGGCGGGGAGGTAGTCGG RPS6KA1 ENSG00000117676 0.6204236511382796 [346,298] [475,330] 9 dCas9-KRAB negative selection 5508621
26551684 26551707 1 - 27260156 BXPC3 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.09762970221620978 [435] [513,367,473,610] 2 hSpCas9 negative selection 5568249
26536948 26536971 1 + 27260156 BXPC3 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.23085856115985492 [545] [615,806,561,687] 5 hSpCas9 negative selection 5568250
26551670 26551693 1 + 27260156 BXPC3 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.011780367593208385 [416] [360,518,414,466] 0 hSpCas9 negative selection 5568251
26536919 26536942 1 + 27260156 BXPC3 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.13225298774899008 [714] [947,622,815,890] 3 hSpCas9 negative selection 5632502
26553453 26553476 1 - 27260156 BXPC3 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.033387523487889426 [319] [356,341,275,324] 0 hSpCas9 negative selection 5632503
26553483 26553506 1 - 27260156 BXPC3 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 -0.07801426627552188 [931] [753,871,1146,940] -2 hSpCas9 negative selection 5632504
26551684 26551707 1 - 27260156 A673 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.46187242876175655 [435] [667,591,640,994] 9 hSpCas9 negative selection 5689500
26536948 26536971 1 + 27260156 A673 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.21102105621069883 [545] [825,647,797,772] 5 hSpCas9 negative selection 5689501
26551670 26551693 1 + 27260156 A673 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.3183756040062954 [416] [636,605,615,639] 7 hSpCas9 negative selection 5689502
26536919 26536942 1 + 27260156 A673 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.09067950824825843 [714] [993,911,901,852] 2 hSpCas9 negative selection 5753753
26553453 26553476 1 - 27260156 A673 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.10711988893724239 [319] [436,335,511,370] 2 hSpCas9 negative selection 5753754
26553483 26553506 1 - 27260156 A673 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.13874273929988 [931] [1172,1185,1170,1399] 3 hSpCas9 negative selection 5753755
26551684 26551707 1 - 27260156 A375 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.5406130590844356 [435] [590,636,942,769] 7 hSpCas9 negative selection 5810751
26536948 26536971 1 + 27260156 A375 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.29827021898350414 [545] [693,1039,801,648] 4 hSpCas9 negative selection 5810752
26551670 26551693 1 + 27260156 A375 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 -0.11812226180552415 [416] [554,548,402,316] -2 hSpCas9 negative selection 5810753
26536919 26536942 1 + 27260156 A375 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.09702462713992577 [714] [938,1079,889,708] 1 hSpCas9 negative selection 5875004
26553453 26553476 1 - 27260156 A375 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.19094939019824353 [319] [340,579,362,439] 2 hSpCas9 negative selection 5875005
26553483 26553506 1 - 27260156 A375 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.10309923770597307 [931] [1160,1241,1291,1006] 1 hSpCas9 negative selection 5875006
26551684 26551707 1 - 27260156 COLO741 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.29471008811413224 [435] [895,666,515] 6 hSpCas9 negative selection 5932002
26536948 26536971 1 + 27260156 COLO741 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 -0.13315621647256373 [545] [817,509,596] -3 hSpCas9 negative selection 5932003
26551670 26551693 1 + 27260156 COLO741 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.4277521753129656 [416] [822,599,732] 8 hSpCas9 negative selection 5932004
26536919 26536942 1 + 27260156 COLO741 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.1285683313068643 [714] [1103,1002,902] 2 hSpCas9 negative selection 5996255
26553453 26553476 1 - 27260156 COLO741 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.3617233291713944 [319] [363,335,261] -6 hSpCas9 negative selection 5996256
26553483 26553506 1 - 27260156 COLO741 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.17089562816355308 [931] [1621,1385,1055] 3 hSpCas9 negative selection 5996257
26551684 26551707 1 - 27260156 CAL120 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.5722017759330267 [435] [1363,583,559] 8 hSpCas9 negative selection 6053253
26536948 26536971 1 + 27260156 CAL120 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.6516874330829757 [545] [1579,1085,620] 8 hSpCas9 negative selection 6053254
26551670 26551693 1 + 27260156 CAL120 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.287406899435361 [416] [665,629,608] 4 hSpCas9 negative selection 6053255
26536919 26536942 1 + 27260156 CAL120 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.18630049152595562 [714] [1202,1218,649] 2 hSpCas9 negative selection 6117506
26553453 26553476 1 - 27260156 CAL120 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.2798107998274437 [319] [383,319,288] -4 hSpCas9 negative selection 6117507
26553483 26553506 1 - 27260156 CAL120 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.3717110722839908 [931] [1308,1529,1630] 5 hSpCas9 negative selection 6117508
26551684 26551707 1 - 27260156 CADOES1 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.45972467675693834 [435] [430,580,586,634] 7 hSpCas9 negative selection 6174504
26536948 26536971 1 + 27260156 CADOES1 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.5752919244451755 [545] [778,647,847,750] 8 hSpCas9 negative selection 6174505
26551670 26551693 1 + 27260156 CADOES1 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.17375122635394893 [416] [629,441,276,398] 3 hSpCas9 negative selection 6174506
26536919 26536942 1 + 27260156 CADOES1 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.13619223141543602 [714] [826,490,606,1007] 2 hSpCas9 negative selection 6238757
26553453 26553476 1 - 27260156 CADOES1 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.034207553694001525 [319] [289,219,400,307] 0 hSpCas9 negative selection 6238758
26553483 26553506 1 - 27260156 CADOES1 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.07685610310542323 [931] [853,998,846,958] 1 hSpCas9 negative selection 6238759
26551684 26551707 1 - 27260156 EWS502 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.3135933831608345 [435] [643,620,477,535] 5 hSpCas9 negative selection 6295755
26536948 26536971 1 + 27260156 EWS502 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.24697774004334339 [545] [572,826,618,733] 4 hSpCas9 negative selection 6295756
26551670 26551693 1 + 27260156 EWS502 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.42669831726002266 [416] [774,508,493,572] 7 hSpCas9 negative selection 6295757
26536919 26536942 1 + 27260156 EWS502 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.3335839013260409 [714] [724,1062,1159,886] 6 hSpCas9 negative selection 6360008
26553453 26553476 1 - 27260156 EWS502 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.22130916764020303 [319] [401,224,427,540] 4 hSpCas9 negative selection 6360009
26553483 26553506 1 - 27260156 EWS502 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.012237922541077473 [931] [1058,910,1061,938] 0 hSpCas9 negative selection 6360010
26551684 26551707 1 - 27260156 EW8 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.6164130833668107 [435] [616,566,534,455] 9 hSpCas9 negative selection 6417006
26536948 26536971 1 + 27260156 EW8 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.19117369577319837 [545] [761,446,557,271] 3 hSpCas9 negative selection 6417007
26551670 26551693 1 + 27260156 EW8 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.07541017309467571 [416] [273,461,360,316] 1 hSpCas9 negative selection 6417008
26536919 26536942 1 + 27260156 EW8 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.14839765926074933 [714] [765,441,351,584] -3 hSpCas9 negative selection 6481259
26553453 26553476 1 - 27260156 EW8 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.10111616194013384 [319] [250,252,148,329] -2 hSpCas9 negative selection 6481260
26553483 26553506 1 - 27260156 EW8 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 -0.05602931695507973 [931] [698,855,653,704] -1 hSpCas9 negative selection 6481261
26551684 26551707 1 - 27260156 CORL105 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.10185617276951739 [435] [590,431,745,456] 2 hSpCas9 negative selection 6538257
26536948 26536971 1 + 27260156 CORL105 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.0677325006408977 [545] [734,536,744,678] 1 hSpCas9 negative selection 6538258
26551670 26551693 1 + 27260156 CORL105 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.07704154972105814 [416] [407,674,495,470] 1 hSpCas9 negative selection 6538259
26536919 26536942 1 + 27260156 CORL105 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.044964174391413314 [714] [744,732,1018,779] -1 hSpCas9 negative selection 6602510
26553453 26553476 1 - 27260156 CORL105 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.24195293517633287 [319] [277,311,632,574] 4 hSpCas9 negative selection 6602511
26553483 26553506 1 - 27260156 CORL105 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 -0.06450364499893435 [931] [998,1061,1198,935] -1 hSpCas9 negative selection 6602512
26551684 26551707 1 - 27260156 HS294T viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 -0.028517993499628663 [435] [144,140,113,282] 0 hSpCas9 negative selection 6659508
26536948 26536971 1 + 27260156 HS294T viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.8288456923366164 [545] [453,538,198,276] 9 hSpCas9 negative selection 6659509
26551670 26551693 1 + 27260156 HS294T viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 -0.5503232032556875 [416] [101,89,96,160] -7 hSpCas9 negative selection 6659510
26536919 26536942 1 + 27260156 HS294T viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.4275432208090506 [714] [226,161,210,223] -6 hSpCas9 negative selection 6723761
26553453 26553476 1 - 27260156 HS294T viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.14154229896602466 [319] [132,176,84,151] 2 hSpCas9 negative selection 6723762
26553483 26553506 1 - 27260156 HS294T viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.5181336893285969 [931] [512,370,506,708] 7 hSpCas9 negative selection 6723763
26551684 26551707 1 - 27260156 HCC44 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.7398458994478045 [435] [849,690,985,809] 9 hSpCas9 negative selection 6780759
26536948 26536971 1 + 27260156 HCC44 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.0587513403871317 [545] [837,411,875,535] 0 hSpCas9 negative selection 6780760
26551670 26551693 1 + 27260156 HCC44 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.18950809106618796 [416] [497,506,670,495] 3 hSpCas9 negative selection 6780761
26536919 26536942 1 + 27260156 HCC44 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.09495523777354253 [714] [882,546,957,711] -1 hSpCas9 negative selection 6845012
26553453 26553476 1 - 27260156 HCC44 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.14837402268196054 [319] [360,426,330,178] -2 hSpCas9 negative selection 6845013
26553483 26553506 1 - 27260156 HCC44 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.01043689238427814 [931] [890,1062,1273,1031] 0 hSpCas9 negative selection 6845014
26551684 26551707 1 - 27260156 G402 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.6332621483088285 [435] [1025,691,843,759] 7 hSpCas9 negative selection 6902010
26536948 26536971 1 + 27260156 G402 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.25111065509573754 [545] [583,898,963,701] 3 hSpCas9 negative selection 6902011
26551670 26551693 1 + 27260156 G402 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.5755597085161517 [416] [710,739,891,682] 7 hSpCas9 negative selection 6902012
26536919 26536942 1 + 27260156 G402 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.1501631512918289 [714] [752,869,587,923] -2 hSpCas9 negative selection 6966263
26553453 26553476 1 - 27260156 G402 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.1745341485463971 [319] [408,284,413,629] 2 hSpCas9 negative selection 6966264
26553483 26553506 1 - 27260156 G402 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.05540203270919741 [931] [1463,1411,1109,808] 0 hSpCas9 negative selection 6966265
26551684 26551707 1 - 27260156 L33 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 -0.3115275733111125 [435] [299,137,249,371] -6 hSpCas9 negative selection 7023261
26536948 26536971 1 + 27260156 L33 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.1500998563277554 [545] [482,275,433,579] 3 hSpCas9 negative selection 7023262
26551670 26551693 1 + 27260156 L33 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 -0.29898649242624176 [416] [361,115,203,384] -6 hSpCas9 negative selection 7023263
26536919 26536942 1 + 27260156 L33 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.28166600199567415 [714] [623,261,333,556] -6 hSpCas9 negative selection 7087514
26553453 26553476 1 - 27260156 L33 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.16963777985983963 [319] [211,106,155,416] -4 hSpCas9 negative selection 7087515
26553483 26553506 1 - 27260156 L33 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.03458692848730316 [931] [827,496,601,823] 0 hSpCas9 negative selection 7087516
26551684 26551707 1 - 27260156 K562 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.05911367349660609 [435] [358,291,393,539] 0 hSpCas9 negative selection 7144512
26536948 26536971 1 + 27260156 K562 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.7800438668330723 [545] [735,1175,356,1040] 8 hSpCas9 negative selection 7144513
26551670 26551693 1 + 27260156 K562 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.2608847302329015 [416] [644,430,356,363] 3 hSpCas9 negative selection 7144514
26536919 26536942 1 + 27260156 K562 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.09646104882999029 [714] [1154,852,573,229] 1 hSpCas9 negative selection 7208765
26553453 26553476 1 - 27260156 K562 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.3153624424492151 [319] [307,632,270,225] 4 hSpCas9 negative selection 7208766
26553483 26553506 1 - 27260156 K562 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 -0.13595824722472338 [931] [989,671,930,463] -2 hSpCas9 negative selection 7208767
26551684 26551707 1 - 27260156 HT29 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.3072615081221233 [435] [680,807,717,451] 6 hSpCas9 negative selection 7265763
26536948 26536971 1 + 27260156 HT29 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.41258474762028885 [545] [762,1189,739,854] 7 hSpCas9 negative selection 7265764
26551670 26551693 1 + 27260156 HT29 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.41856953508242617 [416] [868,660,685,521] 7 hSpCas9 negative selection 7265765
26536919 26536942 1 + 27260156 HT29 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.22257680174526295 [714] [911,1102,1324,742] 4 hSpCas9 negative selection 7330016
26553453 26553476 1 - 27260156 HT29 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.30922210768318154 [319] [406,533,552,434] 6 hSpCas9 negative selection 7330017
26553483 26553506 1 - 27260156 HT29 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.29096076263971293 [931] [1556,1513,1267,1237] 6 hSpCas9 negative selection 7330018
26551684 26551707 1 - 27260156 MHHES1 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 -0.0568635485893037 [435] [577,694,389,291] -1 hSpCas9 negative selection 7387014
26536948 26536971 1 + 27260156 MHHES1 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.5307551602880676 [545] [797,966,821,931] 8 hSpCas9 negative selection 7387015
26551670 26551693 1 + 27260156 MHHES1 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.202759846951329 [416] [727,374,510,540] 4 hSpCas9 negative selection 7387016
26536919 26536942 1 + 27260156 MHHES1 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.01587888755474276 [714] [933,948,808,562] 0 hSpCas9 negative selection 7451267
26553453 26553476 1 - 27260156 MHHES1 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.3305685635021519 [319] [299,348,316,201] -6 hSpCas9 negative selection 7451268
26553483 26553506 1 - 27260156 MHHES1 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.23650079513685995 [931] [1337,1500,1331,872] 4 hSpCas9 negative selection 7451269
26551684 26551707 1 - 27260156 MEWO viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.27968996676425606 [435] [544,505,443] 6 hSpCas9 negative selection 7508265
26536948 26536971 1 + 27260156 MEWO viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 -0.041755831322649706 [545] [696,396,433] -1 hSpCas9 negative selection 7508266
26551670 26551693 1 + 27260156 MEWO viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.18205280769157375 [416] [659,405,303] 4 hSpCas9 negative selection 7508267
26536919 26536942 1 + 27260156 MEWO viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.00449053651523601 [714] [872,469,709] 0 hSpCas9 negative selection 7572518
26553453 26553476 1 - 27260156 MEWO viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.3027527779500223 [319] [305,310,122] -6 hSpCas9 negative selection 7572519
26553483 26553506 1 - 27260156 MEWO viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.12016317013526245 [931] [1083,790,994] 2 hSpCas9 negative selection 7572520
26551684 26551707 1 - 27260156 LNCAPCLONEFGC viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.6199730468451592 [435] [632,540,590,663] 8 hSpCas9 negative selection 7629516
26536948 26536971 1 + 27260156 LNCAPCLONEFGC viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.6135374504493348 [545] [852,671,694,800] 8 hSpCas9 negative selection 7629517
26551670 26551693 1 + 27260156 LNCAPCLONEFGC viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.6253860026641742 [416] [348,624,796,592] 8 hSpCas9 negative selection 7629518
26536919 26536942 1 + 27260156 LNCAPCLONEFGC viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.2041812520046109 [714] [749,460,948,872] 3 hSpCas9 negative selection 7693769
26553453 26553476 1 - 27260156 LNCAPCLONEFGC viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.14693327639141218 [319] [184,321,311,232] -2 hSpCas9 negative selection 7693770
26553483 26553506 1 - 27260156 LNCAPCLONEFGC viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.311906350423239 [931] [1187,782,1356,923] 5 hSpCas9 negative selection 7693771
26551684 26551707 1 - 27260156 PANC0327 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.41282807395810406 [435] [571,535,372,582] 6 hSpCas9 negative selection 7750767
26536948 26536971 1 + 27260156 PANC0327 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.263762546708399 [545] [384,517,568,848] 4 hSpCas9 negative selection 7750768
26551670 26551693 1 + 27260156 PANC0327 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.06978111446602406 [416] [439,437,420,253] 1 hSpCas9 negative selection 7750769
26536919 26536942 1 + 27260156 PANC0327 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.17909028006796324 [714] [703,926,634,581] 2 hSpCas9 negative selection 7815020
26553453 26553476 1 - 27260156 PANC0327 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.10121590238157196 [319] [273,161,315,321] -1 hSpCas9 negative selection 7815021
26553483 26553506 1 - 27260156 PANC0327 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.2574738630215 [931] [1032,916,1304,716] 4 hSpCas9 negative selection 7815022
26551684 26551707 1 - 27260156 NCIH2009 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.26881458447938467 [435] [770,505,934] 3 hSpCas9 negative selection 7872018
26536948 26536971 1 + 27260156 NCIH2009 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.3375598512574265 [545] [1025,1044,829] 4 hSpCas9 negative selection 7872019
26551670 26551693 1 + 27260156 NCIH2009 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 -0.21110839673611648 [416] [513,567,427] -3 hSpCas9 negative selection 7872020
26536919 26536942 1 + 27260156 NCIH2009 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.29124131333896786 [714] [1030,766,692] -4 hSpCas9 negative selection 7936271
26553453 26553476 1 - 27260156 NCIH2009 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.02963578846972237 [319] [560,303,474] 0 hSpCas9 negative selection 7936272
26553483 26553506 1 - 27260156 NCIH2009 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 -0.10389347504604651 [931] [1266,1040,1338] -1 hSpCas9 negative selection 7936273
26551684 26551707 1 - 27260156 NCIH1373 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.5890989090861501 [435] [695,634,802,212] 6 hSpCas9 negative selection 7993269
26536948 26536971 1 + 27260156 NCIH1373 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.3749142171761183 [545] [1481,446,661,189] 3 hSpCas9 negative selection 7993270
26551670 26551693 1 + 27260156 NCIH1373 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 -0.2885070398471753 [416] [532,348,371,77] -3 hSpCas9 negative selection 7993271
26536919 26536942 1 + 27260156 NCIH1373 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.01331800874879252 [714] [717,1253,495,183] 0 hSpCas9 negative selection 8057522
26553453 26553476 1 - 27260156 NCIH1373 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.7932417794120499 [319] [114,127,256,85] -7 hSpCas9 negative selection 8057523
26553483 26553506 1 - 27260156 NCIH1373 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 -0.6051693666418406 [931] [632,510,499,299] -6 hSpCas9 negative selection 8057524
26551684 26551707 1 - 27260156 PATU8902 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.8822937657795259 [435] [1086,1122,1265,931] 8 hSpCas9 negative selection 8114520
26536948 26536971 1 + 27260156 PATU8902 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.8558710475745378 [545] [1367,1403,1215,1570] 8 hSpCas9 negative selection 8114521
26551670 26551693 1 + 27260156 PATU8902 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.5563136527197263 [416] [810,974,785,855] 6 hSpCas9 negative selection 8114522
26536919 26536942 1 + 27260156 PATU8902 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.10045586287605279 [714] [776,1143,731,1132] -1 hSpCas9 negative selection 8178773
26553453 26553476 1 - 27260156 PATU8902 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.27787737238670346 [319] [410,383,485,938] 3 hSpCas9 negative selection 8178774
26553483 26553506 1 - 27260156 PATU8902 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.6198115391252185 [931] [2531,2628,1342,1571] 6 hSpCas9 negative selection 8178775
26551684 26551707 1 - 27260156 PANC1 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.06503596240624339 [435] [390,457,401,332] 1 hSpCas9 negative selection 8235771
26536948 26536971 1 + 27260156 PANC1 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.28677676501984883 [545] [781,719,401,423] 4 hSpCas9 negative selection 8235772
26551670 26551693 1 + 27260156 PANC1 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.13086463455559327 [416] [378,619,310,311] 2 hSpCas9 negative selection 8235773
26536919 26536942 1 + 27260156 PANC1 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.13612776905619117 [714] [485,625,772,386] -2 hSpCas9 negative selection 8300024
26553453 26553476 1 - 27260156 PANC1 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.4570362560538346 [319] [108,334,221,166] -6 hSpCas9 negative selection 8300025
26553483 26553506 1 - 27260156 PANC1 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.03647734688923243 [931] [767,1347,885,441] 0 hSpCas9 negative selection 8300026
26551684 26551707 1 - 27260156 PANC0813 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.23777758061951682 [435] [803,494,549,584] 4 hSpCas9 negative selection 8357022
26536948 26536971 1 + 27260156 PANC0813 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.38982525181462546 [545] [988,730,768,881] 6 hSpCas9 negative selection 8357023
26551670 26551693 1 + 27260156 PANC0813 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.06255678800800324 [416] [481,521,344,682] 1 hSpCas9 negative selection 8357024
26536919 26536942 1 + 27260156 PANC0813 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.23833147081336775 [714] [889,823,696,465] -4 hSpCas9 negative selection 8421275
26553453 26553476 1 - 27260156 PANC0813 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.07360140887157607 [319] [300,287,552,285] -1 hSpCas9 negative selection 8421276
26553483 26553506 1 - 27260156 PANC0813 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.10095491971069925 [931] [1540,1139,1197,866] 1 hSpCas9 negative selection 8421277
26551684 26551707 1 - 27260156 RDES viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.5195987351038935 [435] [587,729,832,735] 8 hSpCas9 negative selection 8478273
26536948 26536971 1 + 27260156 RDES viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.43058600814183157 [545] [633,809,951,1048] 7 hSpCas9 negative selection 8478274
26551670 26551693 1 + 27260156 RDES viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.21087611363331454 [416] [482,469,498,811] 3 hSpCas9 negative selection 8478275
26536919 26536942 1 + 27260156 RDES viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.02285670137282947 [714] [763,932,757,865] 0 hSpCas9 negative selection 8542526
26553453 26553476 1 - 27260156 RDES viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.09563338650408026 [319] [295,433,387,471] 1 hSpCas9 negative selection 8542527
26553483 26553506 1 - 27260156 RDES viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.003631430039823247 [931] [831,980,1127,1445] 0 hSpCas9 negative selection 8542528
26551684 26551707 1 - 27260156 PC3 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.36725177407041315 [435] [276,510,978,728] 7 hSpCas9 negative selection 8599524
26536948 26536971 1 + 27260156 PC3 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.26463397512229975 [545] [324,615,1307,718] 6 hSpCas9 negative selection 8599525
26551670 26551693 1 + 27260156 PC3 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.5204942731317366 [416] [335,443,1147,749] 9 hSpCas9 negative selection 8599526
26536919 26536942 1 + 27260156 PC3 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.03768594472335074 [714] [371,690,1547,734] 0 hSpCas9 negative selection 8663777
26553453 26553476 1 - 27260156 PC3 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.05188894009099421 [319] [225,357,593,252] 1 hSpCas9 negative selection 8663778
26553483 26553506 1 - 27260156 PC3 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.24327118410081894 [931] [728,844,2026,1230] 5 hSpCas9 negative selection 8663779
26551684 26551707 1 - 27260156 PATU8988T viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.5649279819826754 [435] [650,640,502,707] 8 hSpCas9 negative selection 8720775
26536948 26536971 1 + 27260156 PATU8988T viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.2046779995629034 [545] [833,557,583,437] 3 hSpCas9 negative selection 8720776
26551670 26551693 1 + 27260156 PATU8988T viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.001616805623414208 [416] [342,431,375,470] 0 hSpCas9 negative selection 8720777
26536919 26536942 1 + 27260156 PATU8988T viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.035813598002709335 [714] [645,741,694,613] 0 hSpCas9 negative selection 8785028
26553453 26553476 1 - 27260156 PATU8988T viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.11648660131474853 [319] [284,270,242,345] -2 hSpCas9 negative selection 8785029
26553483 26553506 1 - 27260156 PATU8988T viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 -0.15668539595291375 [931] [728,840,727,948] -3 hSpCas9 negative selection 8785030
26551684 26551707 1 - 27260156 T47D viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.28264940957375034 [435] [716,699,501,544] 6 hSpCas9 negative selection 8842026
26536948 26536971 1 + 27260156 T47D viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.22674996755718174 [545] [741,642,675,931] 5 hSpCas9 negative selection 8842027
26551670 26551693 1 + 27260156 T47D viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.1618592191958363 [416] [544,465,506,666] 3 hSpCas9 negative selection 8842028
26536919 26536942 1 + 27260156 T47D viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.007367088067948946 [714] [758,757,793,1015] 0 hSpCas9 negative selection 8906279
26553453 26553476 1 - 27260156 T47D viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.023516155296095964 [319] [341,378,389,353] 0 hSpCas9 negative selection 8906280
26553483 26553506 1 - 27260156 T47D viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.007971950293627406 [931] [1097,1058,1042,1172] 0 hSpCas9 negative selection 8906281
26551684 26551707 1 - 27260156 SU8686 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.19950817863779474 [435] [497,348,558,615] 3 hSpCas9 negative selection 8963277
26536948 26536971 1 + 27260156 SU8686 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.2576416892743951 [545] [634,676,574,700] 4 hSpCas9 negative selection 8963278
26551670 26551693 1 + 27260156 SU8686 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 -0.04405923621488328 [416] [296,410,383,541] -1 hSpCas9 negative selection 8963279
26536919 26536942 1 + 27260156 SU8686 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.33288059304243556 [714] [459,569,423,845] -5 hSpCas9 negative selection 9027530
26553453 26553476 1 - 27260156 SU8686 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.19678178391110823 [319] [368,180,237,325] -3 hSpCas9 negative selection 9027531
26553483 26553506 1 - 27260156 SU8686 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.1354564918331037 [931] [898,972,1044,1181] 2 hSpCas9 negative selection 9027532
26551684 26551707 1 - 27260156 SKES1 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.3757368582435125 [435] [574,505,711,462] 7 hSpCas9 negative selection 9084528
26536948 26536971 1 + 27260156 SKES1 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.11733414365869355 [545] [689,559,580,541] 2 hSpCas9 negative selection 9084529
26551670 26551693 1 + 27260156 SKES1 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.09586062769977603 [416] [606,446,421,333] 2 hSpCas9 negative selection 9084530
26536919 26536942 1 + 27260156 SKES1 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.0644396294375289 [714] [958,600,668,757] 1 hSpCas9 negative selection 9148781
26553453 26553476 1 - 27260156 SKES1 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.11200193018108984 [319] [546,315,196,171] -2 hSpCas9 negative selection 9148782
26553483 26553506 1 - 27260156 SKES1 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.2226511154616767 [931] [1203,1224,1085,871] 5 hSpCas9 negative selection 9148783
26551684 26551707 1 - 27260156 TOV112D viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.2950101707049353 [435] [547,846,478,350] 5 hSpCas9 negative selection 9205779
26536948 26536971 1 + 27260156 TOV112D viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.3722907767722522 [545] [645,632,762,762] 7 hSpCas9 negative selection 9205780
26551670 26551693 1 + 27260156 TOV112D viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.282287548154171 [416] [321,634,493,592] 5 hSpCas9 negative selection 9205781
26536919 26536942 1 + 27260156 TOV112D viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 -0.045696572923855316 [714] [552,828,958,460] -1 hSpCas9 negative selection 9270032
26553453 26553476 1 - 27260156 TOV112D viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 0.044429185421767436 [319] [354,317,225,418] 0 hSpCas9 negative selection 9270033
26553483 26553506 1 - 27260156 TOV112D viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 -0.02671045178351028 [931] [667,1604,791,751] 0 hSpCas9 negative selection 9270034
26551684 26551707 1 - 27260156 TC71 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.3299777632790927 [435] [473,593,612,675] 7 hSpCas9 negative selection 9327030
26536948 26536971 1 + 27260156 TC71 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.1066938248426057 [545] [595,666,663,590] 2 hSpCas9 negative selection 9327031
26551670 26551693 1 + 27260156 TC71 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.184584283670435 [416] [406,486,511,635] 4 hSpCas9 negative selection 9327032
26536919 26536942 1 + 27260156 TC71 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.047120388636904154 [714] [842,753,725,848] 1 hSpCas9 negative selection 9391283
26553453 26553476 1 - 27260156 TC71 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.09678705827169953 [319] [269,348,297,370] -2 hSpCas9 negative selection 9391284
26553483 26553506 1 - 27260156 TC71 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.1629080074557906 [931] [1129,1033,1369,918] 4 hSpCas9 negative selection 9391285
26551684 26551707 1 - 27260156 TC32 viability TGAAGAGGTCCCCACCACGCAGG RPS6KA1 ENSG00000117676 0.33981970510847015 [435] [498,284,835,574] 6 hSpCas9 negative selection 9448281
26536948 26536971 1 + 27260156 TC32 viability AGCTGGACTTCAGCCGTCCAAGG RPS6KA1 ENSG00000117676 0.4442196814125451 [545] [531,499,1184,717] 7 hSpCas9 negative selection 9448282
26551670 26551693 1 + 27260156 TC32 viability CTCATTCTGGACTTCCTGCGTGG RPS6KA1 ENSG00000117676 0.11274547075514874 [416] [517,266,403,529] 2 hSpCas9 negative selection 9448283
26536919 26536942 1 + 27260156 TC32 viability TTCCAGAATGGACAGACCTCAGG RPS6KA1 ENSG00000117676 0.12207888248654852 [714] [565,674,915,800] 2 hSpCas9 negative selection 9512534
26553453 26553476 1 - 27260156 TC32 viability AAATGATACCCAGGCTGTGCAGG RPS6KA1 ENSG00000117676 -0.025365149517813323 [319] [296,183,423,325] 0 hSpCas9 negative selection 9512535
26553483 26553506 1 - 27260156 TC32 viability TCACTCACTTCTCAGGCTTGAGG RPS6KA1 ENSG00000117676 0.2899093273947623 [931] [986,676,1146,1614] 5 hSpCas9 negative selection 9512536
26529946 26529969 1 - 27869803 HPAFII viability after 27 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -0.25956444518960375 [135] [32,81,NaN] -2 hSpCas9 negative selection 9533432
26543207 26543230 1 - 27869803 HPAFII viability after 27 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.13325872161693764 [565] [381,279,NaN] 1 hSpCas9 negative selection 9533433
26544153 26544176 1 - 27869803 HPAFII viability after 27 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 0.821103826246393 [68] [8,109,NaN] 6 hSpCas9 negative selection 9533434
26546023 26546046 1 - 27869803 HPAFII viability after 27 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 -0.10839884272986322 [202] [164,43,NaN] -1 hSpCas9 negative selection 9533435
26546894 26546917 1 + 27869803 HPAFII viability after 27 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.6320153261870258 [245] [137,37,NaN] -4 hSpCas9 negative selection 9533436
26551404 26551427 1 - 27869803 HPAFII viability after 27 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 1.4810603201085566 [145] [348,101,NaN] 9 hSpCas9 negative selection 9533437
26529946 26529969 1 - 27869803 HPAFII viability after 15 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 0.3737827209461597 [135] [263,142,NaN] 4 hSpCas9 negative selection 9615881
26543207 26543230 1 - 27869803 HPAFII viability after 15 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.12838250861845002 [565] [942,491,NaN] 1 hSpCas9 negative selection 9615882
26544153 26544176 1 - 27869803 HPAFII viability after 15 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 0.9505241222749747 [68] [101,168,NaN] 9 hSpCas9 negative selection 9615883
26546023 26546046 1 - 27869803 HPAFII viability after 15 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 0.052322949231256854 [202] [343,152,NaN] 0 hSpCas9 negative selection 9615884
26546894 26546917 1 + 27869803 HPAFII viability after 15 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.07255061895644346 [245] [428,140,NaN] -1 hSpCas9 negative selection 9615885
26551404 26551427 1 - 27869803 HPAFII viability after 15 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 0.4591756934489299 [145] [359,125,NaN] 5 hSpCas9 negative selection 9615886
26529946 26529969 1 - 27869803 ASPC1 viability after 36 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 0.4424925202641864 [281] [38,251,104] 4 hSpCas9 negative selection 9698330
26543207 26543230 1 - 27869803 ASPC1 viability after 36 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 -0.6585870174403917 [1651] [320,588,214] -6 hSpCas9 negative selection 9698331
26544153 26544176 1 - 27869803 ASPC1 viability after 36 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 -2.0340191263021157 [240] [0,41,16] -9 hSpCas9 negative selection 9698332
26546023 26546046 1 - 27869803 ASPC1 viability after 36 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 -0.4080044801804329 [655] [78,157,247] -4 hSpCas9 negative selection 9698333
26546894 26546917 1 + 27869803 ASPC1 viability after 36 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.27817121134036915 [766] [308,218,157] -3 hSpCas9 negative selection 9698334
26551404 26551427 1 - 27869803 ASPC1 viability after 36 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 -0.7058086314961112 [465] [6,111,153] -6 hSpCas9 negative selection 9698335
26529946 26529969 1 - 27869803 PATU8988S viability after 35 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 0.6031421957231304 [316] [165,221,NaN] 6 hSpCas9 negative selection 9780779
26543207 26543230 1 - 27869803 PATU8988S viability after 35 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.13648051006117923 [1421] [863,393,NaN] 1 hSpCas9 negative selection 9780780
26544153 26544176 1 - 27869803 PATU8988S viability after 35 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 1.6179347701883235 [208] [416,98,NaN] 9 hSpCas9 negative selection 9780781
26546023 26546046 1 - 27869803 PATU8988S viability after 35 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 -0.781667451569731 [518] [160,81,NaN] -6 hSpCas9 negative selection 9780782
26546894 26546917 1 + 27869803 PATU8988S viability after 35 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.4414117802991564 [599] [157,197,NaN] -4 hSpCas9 negative selection 9780783
26551404 26551427 1 - 27869803 PATU8988S viability after 35 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 0.9456043773323157 [397] [407,208,NaN] 8 hSpCas9 negative selection 9780784
26529946 26529969 1 - 27869803 PATU8988S viability after 31 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 0.23223798434035103 [316] [140,157,NaN] 3 hSpCas9 negative selection 9863228
26543207 26543230 1 - 27869803 PATU8988S viability after 31 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 -0.298729163807405 [1421] [478,437,NaN] -3 hSpCas9 negative selection 9863229
26544153 26544176 1 - 27869803 PATU8988S viability after 31 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 1.40502567958591 [208] [298,120,NaN] 9 hSpCas9 negative selection 9863230
26546023 26546046 1 - 27869803 PATU8988S viability after 31 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 -0.942452625962287 [518] [130,77,NaN] -7 hSpCas9 negative selection 9863231
26546894 26546917 1 + 27869803 PATU8988S viability after 31 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -0.5877001821262987 [599] [134,189,NaN] -6 hSpCas9 negative selection 9863232
26551404 26551427 1 - 27869803 PATU8988S viability after 31 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 0.6333408256550509 [397] [283,197,NaN] 7 hSpCas9 negative selection 9863233
26529946 26529969 1 - 27869803 HPAFII viability after 35 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 -0.8666297136756105 [135] [25,50,NaN] -5 hSpCas9 negative selection 9945677
26543207 26543230 1 - 27869803 HPAFII viability after 35 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.42490025946015453 [565] [545,202,NaN] 2 hSpCas9 negative selection 9945678
26544153 26544176 1 - 27869803 HPAFII viability after 35 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 1.6053526562844314 [68] [86,127,NaN] 9 hSpCas9 negative selection 9945679
26546023 26546046 1 - 27869803 HPAFII viability after 35 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 -1.6937995723192762 [202] [35,26,NaN] -7 hSpCas9 negative selection 9945680
26546894 26546917 1 + 27869803 HPAFII viability after 35 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 -1.1330487268531466 [245] [92,15,NaN] -6 hSpCas9 negative selection 9945681
26551404 26551427 1 - 27869803 HPAFII viability after 35 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 1.5478377272632833 [145] [304,115,NaN] 9 hSpCas9 negative selection 9945682
26529946 26529969 1 - 27869803 HPAFII viability after 31 days CACTAGCTCCATGAGCGGCCAGG RPS6KA1 ENSG00000117676 0.13699847781967633 [135] [59,109,NaN] 1 hSpCas9 negative selection 10028126
26543207 26543230 1 - 27869803 HPAFII viability after 31 days CTGCTCACCTTTCTGGGACAGGG RPS6KA1 ENSG00000117676 0.5352779079051937 [565] [534,378,NaN] 4 hSpCas9 negative selection 10028127
26544153 26544176 1 - 27869803 HPAFII viability after 31 days GGGCAGATAGGTCTGACACCTGG RPS6KA1 ENSG00000117676 1.498033057257178 [68] [61,160,NaN] 9 hSpCas9 negative selection 10028128
26546023 26546046 1 - 27869803 HPAFII viability after 31 days GCACACTCACCGAGTCCCGCTGG RPS6KA1 ENSG00000117676 -2.0820474165074923 [202] [35,16,NaN] -8 hSpCas9 negative selection 10028129
26546894 26546917 1 + 27869803 HPAFII viability after 31 days ATCACGCACCACGTCAAGGCTGG RPS6KA1 ENSG00000117676 0.05303219617339577 [245] [192,88,NaN] 0 hSpCas9 negative selection 10028130
26551404 26551427 1 - 27869803 HPAFII viability after 31 days TCTCCATCTTGGTCCGGACGCGG RPS6KA1 ENSG00000117676 1.1938536806775897 [145] [308,54,NaN] 8 hSpCas9 negative selection 10028131
26557006 26557029 1 - 28162770 P31FUJ viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 0.0952519932698253 [234] [294] 1 hSpCas9 negative selection 10228071
26558823 26558846 1 - 28162770 P31FUJ viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -0.5817505132354501 [255] [200] -5 hSpCas9 negative selection 10228072
26547204 26547227 1 + 28162770 P31FUJ viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -0.5547302993017411 [69] [55] -5 hSpCas9 negative selection 10228073
26553384 26553407 1 + 28162770 P31FUJ viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.6173023651025626 [303] [547] 7 hSpCas9 negative selection 10228074
26557022 26557045 1 - 28162770 P31FUJ viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 0.47847674608817803 [101] [166] 5 hSpCas9 negative selection 10228075
26558910 26558933 1 + 28162770 P31FUJ viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 0.3308497900613655 [340] [503] 3 hSpCas9 negative selection 10228076
26561535 26561558 1 + 28162770 P31FUJ viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 -0.10385434719699428 [245] [268] -1 hSpCas9 negative selection 10228077
26561585 26561608 1 + 28162770 P31FUJ viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 0.00709012160697213 [198] [234] 0 hSpCas9 negative selection 10228078
26555164 26555187 1 + 28162770 P31FUJ viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -0.1642708227435632 [554] [581] -1 hSpCas9 negative selection 10228079
26555553 26555576 1 - 28162770 P31FUJ viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 0.5745527176432255 [107] [188] 6 hSpCas9 negative selection 10228080
26557006 26557029 1 - 28162770 TF1 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 NaN [NaN] [40] 1 hSpCas9 negative selection 10397437
26558823 26558846 1 - 28162770 TF1 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 NaN [NaN] [127] 1 hSpCas9 negative selection 10397438
26547204 26547227 1 + 28162770 TF1 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 NaN [NaN] [25] 1 hSpCas9 negative selection 10397439
26553384 26553407 1 + 28162770 TF1 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 NaN [NaN] [132] 1 hSpCas9 negative selection 10397440
26557022 26557045 1 - 28162770 TF1 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 NaN [NaN] [57] 1 hSpCas9 negative selection 10397441
26558910 26558933 1 + 28162770 TF1 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 NaN [NaN] [199] 1 hSpCas9 negative selection 10397442
26561535 26561558 1 + 28162770 TF1 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 NaN [NaN] [263] 1 hSpCas9 negative selection 10397443
26561585 26561608 1 + 28162770 TF1 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 NaN [NaN] [89] 1 hSpCas9 negative selection 10397444
26555164 26555187 1 + 28162770 TF1 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 NaN [NaN] [296] 1 hSpCas9 negative selection 10397445
26555553 26555576 1 - 28162770 TF1 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 NaN [NaN] [45] 1 hSpCas9 negative selection 10397446
26557006 26557029 1 - 28162770 SKM1 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 -1.1137678223991154 [70] [57] -7 hSpCas9 negative selection 10566803
26558823 26558846 1 - 28162770 SKM1 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -1.4894263589351346 [53] [33] -7 hSpCas9 negative selection 10566804
26547204 26547227 1 + 28162770 SKM1 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 0.0625210845580586 [12] [23] 0 hSpCas9 negative selection 10566805
26553384 26553407 1 + 28162770 SKM1 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.088361089493318 [82] [155] 0 hSpCas9 negative selection 10566806
26557022 26557045 1 - 28162770 SKM1 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 -1.0388130870951537 [42] [36] -6 hSpCas9 negative selection 10566807
26558910 26558933 1 + 28162770 SKM1 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 -0.3936673761297038 [80] [108] -3 hSpCas9 negative selection 10566808
26561535 26561558 1 + 28162770 SKM1 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 -0.42968427524324515 [47] [62] -4 hSpCas9 negative selection 10566809
26561585 26561608 1 + 28162770 SKM1 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 -0.3118069657028216 [32] [46] -3 hSpCas9 negative selection 10566810
26555164 26555187 1 + 28162770 SKM1 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -0.18627608361896242 [120] [187] -1 hSpCas9 negative selection 10566811
26555553 26555576 1 - 28162770 SKM1 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 -0.028452575489431586 [14] [25] 0 hSpCas9 negative selection 10566812
26557006 26557029 1 - 28162770 SKM1 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 -1.1137678223991154 [70] [57] -7 hSpCas9 negative selection 10736169
26558823 26558846 1 - 28162770 SKM1 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -1.4894263589351346 [53] [33] -7 hSpCas9 negative selection 10736170
26547204 26547227 1 + 28162770 SKM1 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 0.0625210845580586 [12] [23] 0 hSpCas9 negative selection 10736171
26553384 26553407 1 + 28162770 SKM1 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.088361089493318 [82] [155] 0 hSpCas9 negative selection 10736172
26557022 26557045 1 - 28162770 SKM1 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 -1.0388130870951537 [42] [36] -6 hSpCas9 negative selection 10736173
26558910 26558933 1 + 28162770 SKM1 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 -0.3936673761297038 [80] [108] -3 hSpCas9 negative selection 10736174
26561535 26561558 1 + 28162770 SKM1 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 -0.42968427524324515 [47] [62] -4 hSpCas9 negative selection 10736175
26561585 26561608 1 + 28162770 SKM1 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 -0.3118069657028216 [32] [46] -3 hSpCas9 negative selection 10736176
26555164 26555187 1 + 28162770 SKM1 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -0.18627608361896242 [120] [187] -1 hSpCas9 negative selection 10736177
26555553 26555576 1 - 28162770 SKM1 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 -0.028452575489431586 [14] [25] 0 hSpCas9 negative selection 10736178
26557006 26557029 1 - 28162770 PL21 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 -1.1894271972734054 [261] [49] -7 hSpCas9 negative selection 10905535
26558823 26558846 1 - 28162770 PL21 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -2.8873232267610196 [169] [9] -9 hSpCas9 negative selection 10905536
26547204 26547227 1 + 28162770 PL21 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -0.05224754714496527 [80] [33] 0 hSpCas9 negative selection 10905537
26553384 26553407 1 + 28162770 PL21 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.712741892147955 [292] [208] 6 hSpCas9 negative selection 10905538
26557022 26557045 1 - 28162770 PL21 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 -0.18233002233309314 [145] [55] -1 hSpCas9 negative selection 10905539
26558910 26558933 1 + 28162770 PL21 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 -0.5626841475979119 [318] [93] -4 hSpCas9 negative selection 10905540
26561535 26561558 1 + 28162770 PL21 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 0.33560303178443884 [192] [105] 3 hSpCas9 negative selection 10905541
26561585 26561608 1 + 28162770 PL21 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 -0.18591881781775776 [114] [43] -1 hSpCas9 negative selection 10905542
26555164 26555187 1 + 28162770 PL21 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -0.2958178801730912 [439] [155] -2 hSpCas9 negative selection 10905543
26555553 26555576 1 - 28162770 PL21 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 -0.13170394926312512 [72] [28] -1 hSpCas9 negative selection 10905544
26557006 26557029 1 - 28162770 P31FUJ viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 0.0952519932698253 [234] [294] 1 hSpCas9 negative selection 11074901
26558823 26558846 1 - 28162770 P31FUJ viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -0.5817505132354501 [255] [200] -5 hSpCas9 negative selection 11074902
26547204 26547227 1 + 28162770 P31FUJ viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -0.5547302993017411 [69] [55] -5 hSpCas9 negative selection 11074903
26553384 26553407 1 + 28162770 P31FUJ viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.6173023651025626 [303] [547] 7 hSpCas9 negative selection 11074904
26557022 26557045 1 - 28162770 P31FUJ viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 0.47847674608817803 [101] [166] 5 hSpCas9 negative selection 11074905
26558910 26558933 1 + 28162770 P31FUJ viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 0.3308497900613655 [340] [503] 3 hSpCas9 negative selection 11074906
26561535 26561558 1 + 28162770 P31FUJ viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 -0.10385434719699428 [245] [268] -1 hSpCas9 negative selection 11074907
26561585 26561608 1 + 28162770 P31FUJ viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 0.00709012160697213 [198] [234] 0 hSpCas9 negative selection 11074908
26555164 26555187 1 + 28162770 P31FUJ viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -0.1642708227435632 [554] [581] -1 hSpCas9 negative selection 11074909
26555553 26555576 1 - 28162770 P31FUJ viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 0.5745527176432255 [107] [188] 6 hSpCas9 negative selection 11074910
26557006 26557029 1 - 28162770 OCIAML5 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 0.7364018733586947 [136] [411] 6 hSpCas9 negative selection 11244267
26558823 26558846 1 - 28162770 OCIAML5 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -1.093884490788095 [161] [136] -6 hSpCas9 negative selection 11244268
26547204 26547227 1 + 28162770 OCIAML5 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -1.1891015581415676 [47] [37] -6 hSpCas9 negative selection 11244269
26553384 26553407 1 + 28162770 OCIAML5 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.987317205386245 [139] [500] 8 hSpCas9 negative selection 11244270
26557022 26557045 1 - 28162770 OCIAML5 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 0.5002351730668843 [93] [239] 4 hSpCas9 negative selection 11244271
26558910 26558933 1 + 28162770 OCIAML5 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 0.061633582741782655 [154] [291] 0 hSpCas9 negative selection 11244272
26561535 26561558 1 + 28162770 OCIAML5 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 0.5568964140051625 [118] [315] 5 hSpCas9 negative selection 11244273
26561585 26561608 1 + 28162770 OCIAML5 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 1.1827634132991018 [132] [544] 8 hSpCas9 negative selection 11244274
26555164 26555187 1 + 28162770 OCIAML5 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 0.47993078193463257 [256] [646] 4 hSpCas9 negative selection 11244275
26555553 26555576 1 - 28162770 OCIAML5 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 0.9180073351141476 [55] [190] 7 hSpCas9 negative selection 11244276
26557006 26557029 1 - 28162770 EOL1 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 -0.09611169899555855 [421] [207] 0 hSpCas9 negative selection 11413633
26558823 26558846 1 - 28162770 EOL1 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -1.8956311908446533 [225] [31] -8 hSpCas9 negative selection 11413634
26547204 26547227 1 + 28162770 EOL1 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -0.1706094614698055 [93] [43] -1 hSpCas9 negative selection 11413635
26553384 26553407 1 + 28162770 EOL1 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.5164131325463787 [555] [418] 5 hSpCas9 negative selection 11413636
26557022 26557045 1 - 28162770 EOL1 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 0.12484642205636577 [281] [161] 1 hSpCas9 negative selection 11413637
26558910 26558933 1 + 28162770 EOL1 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 -0.3227622819702428 [583] [245] -2 hSpCas9 negative selection 11413638
26561535 26561558 1 + 28162770 EOL1 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 -0.699484293829214 [261] [84] -5 hSpCas9 negative selection 11413639
26561585 26561608 1 + 28162770 EOL1 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 0.21480364613935277 [174] [106] 2 hSpCas9 negative selection 11413640
26555164 26555187 1 + 28162770 EOL1 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -0.6778418009088059 [582] [191] -5 hSpCas9 negative selection 11413641
26555553 26555576 1 - 28162770 EOL1 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 0.7980153656416031 [130] [119] 7 hSpCas9 negative selection 11413642
26557006 26557029 1 - 28162770 MOLM13 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 -1.3680346927097964 [356] [99] -6 hSpCas9 negative selection 11582999
26558823 26558846 1 - 28162770 MOLM13 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -3.760929308951302 [224] [11] -9 hSpCas9 negative selection 11583000
26547204 26547227 1 + 28162770 MOLM13 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -1.4174680525142986 [132] [35] -6 hSpCas9 negative selection 11583001
26553384 26553407 1 + 28162770 MOLM13 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 -0.9202724117428703 [389] [148] -5 hSpCas9 negative selection 11583002
26557022 26557045 1 - 28162770 MOLM13 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 -2.2246015834810224 [180] [27] -7 hSpCas9 negative selection 11583003
26558910 26558933 1 + 28162770 MOLM13 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 -0.24073158692766555 [419] [256] -1 hSpCas9 negative selection 11583004
26561535 26561558 1 + 28162770 MOLM13 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 -1.9173036068008 [302] [57] -7 hSpCas9 negative selection 11583005
26561585 26561608 1 + 28162770 MOLM13 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 -2.109035800111159 [178] [29] -7 hSpCas9 negative selection 11583006
26555164 26555187 1 + 28162770 MOLM13 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -1.676642462469336 [534] [120] -7 hSpCas9 negative selection 11583007
26555553 26555576 1 - 28162770 MOLM13 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 -1.9269702357966345 [141] [26] -7 hSpCas9 negative selection 11583008
26557006 26557029 1 - 28162770 HEL viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 -0.12923321199376234 [291] [170] -1 hSpCas9 negative selection 11752365
26558823 26558846 1 - 28162770 HEL viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -1.6244833707968704 [206] [42] -7 hSpCas9 negative selection 11752366
26547204 26547227 1 + 28162770 HEL viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -0.7606168622308513 [81] [30] -5 hSpCas9 negative selection 11752367
26553384 26553407 1 + 28162770 HEL viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.31523689228840246 [388] [309] 2 hSpCas9 negative selection 11752368
26557022 26557045 1 - 28162770 HEL viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 0.2782502748849488 [214] [166] 2 hSpCas9 negative selection 11752369
26558910 26558933 1 + 28162770 HEL viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 0.6074057588880762 [371] [362] 5 hSpCas9 negative selection 11752370
26561535 26561558 1 + 28162770 HEL viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 -0.7598077230952901 [229] [86] -5 hSpCas9 negative selection 11752371
26561585 26561608 1 + 28162770 HEL viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 0.6145419401697049 [154] [151] 5 hSpCas9 negative selection 11752372
26555164 26555187 1 + 28162770 HEL viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -0.4755811351884045 [507] [233] -3 hSpCas9 negative selection 11752373
26555553 26555576 1 - 28162770 HEL viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 -0.3732027118686647 [90] [44] -3 hSpCas9 negative selection 11752374
26557006 26557029 1 - 28162770 MV411 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 -0.7040639315260349 [233] [120] -5 hSpCas9 negative selection 11921731
26558823 26558846 1 - 28162770 MV411 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -1.8918372378193526 [162] [36] -8 hSpCas9 negative selection 11921732
26547204 26547227 1 + 28162770 MV411 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -0.5540167698351444 [60] [34] -4 hSpCas9 negative selection 11921733
26553384 26553407 1 + 28162770 MV411 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.21680593212911198 [237] [232] 1 hSpCas9 negative selection 11921734
26557022 26557045 1 - 28162770 MV411 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 -0.07238288114259579 [170] [136] 0 hSpCas9 negative selection 11921735
26558910 26558933 1 + 28162770 MV411 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 0.019168563109658088 [245] [209] 0 hSpCas9 negative selection 11921736
26561535 26561558 1 + 28162770 MV411 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 0.07516860887216387 [230] [204] 0 hSpCas9 negative selection 11921737
26561585 26561608 1 + 28162770 MV411 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 0.33341077389262813 [113] [120] 3 hSpCas9 negative selection 11921738
26555164 26555187 1 + 28162770 MV411 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -0.8477196822575648 [281] [131] -5 hSpCas9 negative selection 11921739
26555553 26555576 1 - 28162770 MV411 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 -0.27193660831080413 [85] [59] -2 hSpCas9 negative selection 11921740
26557006 26557029 1 - 28162770 MONOMAC1 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 0.6766174190750331 [160] [294] 6 hSpCas9 negative selection 12091097
26558823 26558846 1 - 28162770 MONOMAC1 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 0.5596920019280824 [115] [195] 5 hSpCas9 negative selection 12091098
26547204 26547227 1 + 28162770 MONOMAC1 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 1.060760910408093 [45] [109] 8 hSpCas9 negative selection 12091099
26553384 26553407 1 + 28162770 MONOMAC1 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 0.9870670895525205 [179] [408] 8 hSpCas9 negative selection 12091100
26557022 26557045 1 - 28162770 MONOMAC1 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 0.31880129300678217 [113] [162] 3 hSpCas9 negative selection 12091101
26558910 26558933 1 + 28162770 MONOMAC1 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 -0.19024768139691461 [211] [212] -2 hSpCas9 negative selection 12091102
26561535 26561558 1 + 28162770 MONOMAC1 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 0.09341301635464055 [138] [169] 0 hSpCas9 negative selection 12091103
26561585 26561608 1 + 28162770 MONOMAC1 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 -0.8510409922103611 [106] [67] -6 hSpCas9 negative selection 12091104
26555164 26555187 1 + 28162770 MONOMAC1 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 0.2774491173000331 [207] [288] 3 hSpCas9 negative selection 12091105
26555553 26555576 1 - 28162770 MONOMAC1 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 -0.4085409522532656 [65] [56] -4 hSpCas9 negative selection 12091106
26557006 26557029 1 - 28162770 OCIAML2 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 -2.040945549998916 [48] [65] -8 hSpCas9 negative selection 12260463
26558823 26558846 1 - 28162770 OCIAML2 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -2.6475075873262406 [25] [22] -9 hSpCas9 negative selection 12260464
26547204 26547227 1 + 28162770 OCIAML2 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -2.3331263014922263 [19] [21] -8 hSpCas9 negative selection 12260465
26553384 26553407 1 + 28162770 OCIAML2 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 -0.6595325014987403 [54] [192] -5 hSpCas9 negative selection 12260466
26557022 26557045 1 - 28162770 OCIAML2 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 -1.615019734577336 [20] [37] -7 hSpCas9 negative selection 12260467
26558910 26558933 1 + 28162770 OCIAML2 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 -1.5071557012672754 [59] [116] -7 hSpCas9 negative selection 12260468
26561535 26561558 1 + 28162770 OCIAML2 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 -2.237969068451886 [39] [46] -8 hSpCas9 negative selection 12260469
26561585 26561608 1 + 28162770 OCIAML2 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 -1.0921182019884315 [19] [51] -6 hSpCas9 negative selection 12260470
26555164 26555187 1 + 28162770 OCIAML2 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -2.2115426039250305 [60] [72] -8 hSpCas9 negative selection 12260471
26555553 26555576 1 - 28162770 OCIAML2 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 -4.345098943158303 [10] [2] -9 hSpCas9 negative selection 12260472
26557006 26557029 1 - 28162770 OCIAML3 viability AGGGTGGCTTGATCTCACGACGG RPS6KA1 ENSG00000117676 -3.354819976444737 [60] [17] -9 hSpCas9 negative selection 12429829
26558823 26558846 1 - 28162770 OCIAML3 viability GCTGATGGGCCCCAGCGCTGGGG RPS6KA1 ENSG00000117676 -2.7562790692230403 [46] [20] -9 hSpCas9 negative selection 12429830
26547204 26547227 1 + 28162770 OCIAML3 viability AAAGTCACCCGGCCTGACAGTGG RPS6KA1 ENSG00000117676 -2.487092436407651 [12] [6] -9 hSpCas9 negative selection 12429831
26553384 26553407 1 + 28162770 OCIAML3 viability TTTGCAGGTGATGTTCACGGAGG RPS6KA1 ENSG00000117676 -0.6709696221390472 [76] [145] -5 hSpCas9 negative selection 12429832
26557022 26557045 1 - 28162770 OCIAML3 viability GCCACTGCTGGCTTGAAGGGTGG RPS6KA1 ENSG00000117676 -1.4829763279354191 [24] [26] -7 hSpCas9 negative selection 12429833
26558910 26558933 1 + 28162770 OCIAML3 viability GCAGGCACCCCTGCACTCGGTGG RPS6KA1 ENSG00000117676 -0.5501533507347358 [80] [166] -4 hSpCas9 negative selection 12429834
26561535 26561558 1 + 28162770 OCIAML3 viability GTGACAGAGCTGATGCGGGGTGG RPS6KA1 ENSG00000117676 -0.08250730154402813 [46] [133] 0 hSpCas9 negative selection 12429835
26561585 26561608 1 + 28162770 OCIAML3 viability GAAGTTCTTCTCAGAGCGGGAGG RPS6KA1 ENSG00000117676 -1.0221012924284532 [36] [54] -6 hSpCas9 negative selection 12429836
26555164 26555187 1 + 28162770 OCIAML3 viability CGGGCTCCCTGCCCTTCCAGGGG RPS6KA1 ENSG00000117676 -0.8291630135825205 [122] [208] -6 hSpCas9 negative selection 12429837
26555553 26555576 1 - 28162770 OCIAML3 viability GCTTCAGTGCTCAGAAACTGGGG RPS6KA1 ENSG00000117676 -3.8164000616606115 [27] [5] -9 hSpCas9 negative selection 12429838