Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6196
• Symbol: RPS6KA2
• Description: ribosomal protein S6 kinase A2

DataSource: http://genomecrispr.dkfz.de/#!/results/RPS6KA2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
166504544	166504567	6	+	26472758	Jiyoye	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	1.471305718925589	[32]	[68]	8	hSpCas9	negative selection	140232
166538766	166538789	6	-	26472758	Jiyoye	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	5.2651563766334455	[0]	[28]	9	hSpCas9	negative selection	140233
166490684	166490707	6	-	26472758	Jiyoye	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-2.0078621177729703	[159]	[29]	-8	hSpCas9	negative selection	140234
166488884	166488907	6	-	26472758	Jiyoye	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	-0.15470350610224132	[92]	[62]	-1	hSpCas9	negative selection	140235
166469849	166469872	6	+	26472758	Jiyoye	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	-0.3508518281881626	[114]	[67]	-3	hSpCas9	negative selection	140236
166459506	166459529	6	-	26472758	Jiyoye	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	0.2571499375012659	[80]	[72]	2	hSpCas9	negative selection	140237
166448786	166448809	6	-	26472758	Jiyoye	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	2.061179526656681	[33]	[106]	8	hSpCas9	negative selection	140238
166430559	166430582	6	-	26472758	Jiyoye	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	-2.293264336635219	[194]	[29]	-8	hSpCas9	negative selection	140239
166419931	166419954	6	-	26472758	Jiyoye	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	0.25266543245024853	[127]	[114]	2	hSpCas9	negative selection	140240
166413856	166413879	6	-	26472758	Jiyoye	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	1.4282369970337032	[67]	[137]	8	hSpCas9	negative selection	140241
166504544	166504567	6	+	26472758	KBM7	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	0.4817717933789813	[237,245]	[179,141]	5	hSpCas9	negative selection	331350
166538766	166538789	6	-	26472758	KBM7	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	1.184873424587764	[144,229]	[308,113]	9	hSpCas9	negative selection	331351
166490684	166490707	6	-	26472758	KBM7	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-2.463448100263598	[900,790]	[90,54]	-9	hSpCas9	negative selection	331352
166488884	166488907	6	-	26472758	KBM7	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	-0.06605521516020763	[327,371]	[149,166]	0	hSpCas9	negative selection	331353
166469849	166469872	6	+	26472758	KBM7	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	-0.2786921403721584	[476,410]	[225,122]	-3	hSpCas9	negative selection	331354
166459506	166459529	6	-	26472758	KBM7	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	0.7220911229386481	[184,154]	[134,127]	7	hSpCas9	negative selection	331355
166448786	166448809	6	-	26472758	KBM7	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	-0.1726241744463921	[470,376]	[227,128]	-2	hSpCas9	negative selection	331356
166430559	166430582	6	-	26472758	KBM7	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	0.35860273263100867	[563,392]	[310,260]	4	hSpCas9	negative selection	331357
166419931	166419954	6	-	26472758	KBM7	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	0.5798101231607691	[930,793]	[704,513]	6	hSpCas9	negative selection	331358
166413856	166413879	6	-	26472758	KBM7	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	0.33584612147422066	[586,401]	[406,183]	3	hSpCas9	negative selection	331359
166504544	166504567	6	+	26472758	Raji	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	1.2329144174574584	[54]	[29]	9	hSpCas9	negative selection	522468
166538766	166538789	6	-	26472758	Raji	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.016944599628602175	[108]	[24]	0	hSpCas9	negative selection	522469
166490684	166490707	6	-	26472758	Raji	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-1.7177826628004653	[325]	[22]	-8	hSpCas9	negative selection	522470
166488884	166488907	6	-	26472758	Raji	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	0.03462719293828509	[121]	[28]	0	hSpCas9	negative selection	522471
166469849	166469872	6	+	26472758	Raji	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	0.9333541355985506	[87]	[38]	8	hSpCas9	negative selection	522472
166459506	166459529	6	-	26472758	Raji	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	1.2374440759379723	[52]	[28]	9	hSpCas9	negative selection	522473
166448786	166448809	6	-	26472758	Raji	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	0.5854308321782438	[111]	[38]	5	hSpCas9	negative selection	522474
166430559	166430582	6	-	26472758	Raji	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	-0.4472053163040379	[328]	[55]	-4	hSpCas9	negative selection	522475
166419931	166419954	6	-	26472758	Raji	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	-0.8869699014852586	[509]	[63]	-6	hSpCas9	negative selection	522476
166413856	166413879	6	-	26472758	Raji	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	-0.22326177661487184	[331]	[65]	-2	hSpCas9	negative selection	522477
166504544	166504567	6	+	26472758	K562	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	0.5521529409710547	[142]	[176]	4	hSpCas9	negative selection	713586
166538766	166538789	6	-	26472758	K562	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	1.482930814366172	[88]	[209]	9	hSpCas9	negative selection	713587
166490684	166490707	6	-	26472758	K562	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-2.2528149236832347	[637]	[112]	-7	hSpCas9	negative selection	713588
166488884	166488907	6	-	26472758	K562	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	1.1002140047818043	[204]	[370]	8	hSpCas9	negative selection	713589
166469849	166469872	6	+	26472758	K562	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	0.31480805555784475	[279]	[293]	2	hSpCas9	negative selection	713590
166459506	166459529	6	-	26472758	K562	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	0.41637141045574166	[157]	[177]	3	hSpCas9	negative selection	713591
166448786	166448809	6	-	26472758	K562	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	-0.27298048924207496	[291]	[203]	-2	hSpCas9	negative selection	713592
166430559	166430582	6	-	26472758	K562	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	0.39157242145010085	[446]	[494]	3	hSpCas9	negative selection	713593
166419931	166419954	6	-	26472758	K562	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	-1.3547576322744104	[611]	[201]	-6	hSpCas9	negative selection	713594
166413856	166413879	6	-	26472758	K562	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	0.41973698787897784	[355]	[401]	3	hSpCas9	negative selection	713595
166498529	166498552	6	-	26627737	DLD1	viability	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	1.0744696750489258	[109]	[65,75,74]	8	hSpCas9	negative selection	831277
166504594	166504617	6	-	26627737	DLD1	viability	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	1.2879417028082627	[449]	[451,314,272]	9	hSpCas9	negative selection	831278
166508267	166508290	6	-	26627737	DLD1	viability	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.3768318535832085	[1688]	[436,949,681]	4	hSpCas9	negative selection	831279
166510331	166510354	6	-	26627737	DLD1	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.7296762163410943	[352]	[100,211,229]	7	hSpCas9	negative selection	831280
166538724	166538747	6	-	26627737	DLD1	viability	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.893975954785582	[416]	[187,320,223]	8	hSpCas9	negative selection	831281
166626918	166626941	6	+	26627737	DLD1	viability	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	-0.13741380806628523	[131]	[67,33,13]	-1	hSpCas9	negative selection	831282
166498529	166498552	6	-	26627737	GBM cells	viability after 5 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	-0.4077474633483664	[46]	[14,22]	-6	hSpCas9	negative selection	913592
166504594	166504617	6	-	26627737	GBM cells	viability after 5 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	0.37946878508873694	[338]	[249,222]	6	hSpCas9	negative selection	913593
166508267	166508290	6	-	26627737	GBM cells	viability after 5 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.34637285185690714	[868]	[625,558]	5	hSpCas9	negative selection	913594
166510331	166510354	6	-	26627737	GBM cells	viability after 5 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.25525705524207465	[295]	[145,119]	-4	hSpCas9	negative selection	913595
166538724	166538747	6	-	26627737	GBM cells	viability after 5 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-0.02386662265241865	[290]	[149,156]	0	hSpCas9	negative selection	913596
166626918	166626941	6	+	26627737	GBM cells	viability after 5 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	-0.3728907405758404	[98]	[45,35]	-5	hSpCas9	negative selection	913597
166498529	166498552	6	-	26627737	GBM cells	viability after 13 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	0.5571813570350117	[46]	[47,28]	7	hSpCas9	negative selection	995907
166504594	166504617	6	-	26627737	GBM cells	viability after 13 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	0.329766528361111	[338]	[298,175]	4	hSpCas9	negative selection	995908
166508267	166508290	6	-	26627737	GBM cells	viability after 13 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.2862535551770595	[868]	[601,552]	3	hSpCas9	negative selection	995909
166510331	166510354	6	-	26627737	GBM cells	viability after 13 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.3377470401004559	[295]	[152,105]	-4	hSpCas9	negative selection	995910
166538724	166538747	6	-	26627737	GBM cells	viability after 13 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-0.27242964889773713	[290]	[122,136]	-3	hSpCas9	negative selection	995911
166626918	166626941	6	+	26627737	GBM cells	viability after 13 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	-0.1436271515149703	[98]	[57,40]	-2	hSpCas9	negative selection	995912
166498529	166498552	6	-	26627737	GBM cells	viability after 21 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	-0.8670006300043749	[46]	[13,13]	-6	hSpCas9	negative selection	1078222
166504594	166504617	6	-	26627737	GBM cells	viability after 21 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-0.07699841477860764	[338]	[183,165]	0	hSpCas9	negative selection	1078223
166508267	166508290	6	-	26627737	GBM cells	viability after 21 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.43136499827653263	[868]	[644,628]	4	hSpCas9	negative selection	1078224
166510331	166510354	6	-	26627737	GBM cells	viability after 21 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.10704234741418295	[295]	[141,155]	-1	hSpCas9	negative selection	1078225
166538724	166538747	6	-	26627737	GBM cells	viability after 21 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-0.828368378266034	[290]	[99,78]	-6	hSpCas9	negative selection	1078226
166626918	166626941	6	+	26627737	GBM cells	viability after 21 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	-0.835834953657282	[98]	[26,32]	-6	hSpCas9	negative selection	1078227
166498529	166498552	6	-	26627737	RPE1	viability after 9 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	4.150160556084181	[40]	[178,290]	9	hSpCas9	negative selection	1160537
166504594	166504617	6	-	26627737	RPE1	viability after 9 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-1.053239723788733	[1336]	[240,150]	-6	hSpCas9	negative selection	1160538
166508267	166508290	6	-	26627737	RPE1	viability after 9 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	-0.458505555796187	[4030]	[834,1025]	-3	hSpCas9	negative selection	1160539
166510331	166510354	6	-	26627737	RPE1	viability after 9 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.3146052957679654	[786]	[360,235]	2	hSpCas9	negative selection	1160540
166538724	166538747	6	-	26627737	RPE1	viability after 9 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-0.06816029872272583	[919]	[141,445]	0	hSpCas9	negative selection	1160541
166626918	166626941	6	+	26627737	RPE1	viability after 9 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	1.1643143401992249	[181]	[104,156]	7	hSpCas9	negative selection	1160542
166498529	166498552	6	-	26627737	RPE1	viability after 12 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	4.377043017904602	[40]	[224,232]	9	hSpCas9	negative selection	1242852
166504594	166504617	6	-	26627737	RPE1	viability after 12 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-1.2200133833925428	[1336]	[228,74]	-7	hSpCas9	negative selection	1242853
166508267	166508290	6	-	26627737	RPE1	viability after 12 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	-0.019535910022889347	[4030]	[963,1178]	0	hSpCas9	negative selection	1242854
166510331	166510354	6	-	26627737	RPE1	viability after 12 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.0414147364090257	[786]	[186,224]	0	hSpCas9	negative selection	1242855
166538724	166538747	6	-	26627737	RPE1	viability after 12 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.5245010233181777	[919]	[271,443]	3	hSpCas9	negative selection	1242856
166626918	166626941	6	+	26627737	RPE1	viability after 12 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	0.8640502024408394	[181]	[88,88]	5	hSpCas9	negative selection	1242857
166498529	166498552	6	-	26627737	RPE1	viability after 15 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	3.553338741283093	[40]	[70,198]	9	hSpCas9	negative selection	1325167
166504594	166504617	6	-	26627737	RPE1	viability after 15 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-1.0704566252945162	[1336]	[174,184]	-6	hSpCas9	negative selection	1325168
166508267	166508290	6	-	26627737	RPE1	viability after 15 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	-0.16204268125556132	[4030]	[1123,917]	-1	hSpCas9	negative selection	1325169
166510331	166510354	6	-	26627737	RPE1	viability after 15 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.39025773373510253	[786]	[247,333]	2	hSpCas9	negative selection	1325170
166538724	166538747	6	-	26627737	RPE1	viability after 15 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.8399405679430666	[919]	[474,456]	5	hSpCas9	negative selection	1325171
166626918	166626941	6	+	26627737	RPE1	viability after 15 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	-0.6487907710171519	[181]	[41,23]	-4	hSpCas9	negative selection	1325172
166498529	166498552	6	-	26627737	RPE1	viability after 18 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	4.595370747510387	[40]	[222,314]	9	hSpCas9	negative selection	1407482
166504594	166504617	6	-	26627737	RPE1	viability after 18 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-1.1238291588804108	[1336]	[152,178]	-6	hSpCas9	negative selection	1407483
166508267	166508290	6	-	26627737	RPE1	viability after 18 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	-0.1022752349563798	[4030]	[849,1187]	0	hSpCas9	negative selection	1407484
166510331	166510354	6	-	26627737	RPE1	viability after 18 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.29559816353331186	[786]	[265,254]	2	hSpCas9	negative selection	1407485
166538724	166538747	6	-	26627737	RPE1	viability after 18 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.9963328785181561	[919]	[299,703]	6	hSpCas9	negative selection	1407486
166626918	166626941	6	+	26627737	RPE1	viability after 18 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	-0.5891467061112889	[181]	[36,27]	-4	hSpCas9	negative selection	1407487
166498529	166498552	6	-	26627737	HeLa	viability after 8 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	0.359498667494071	[93]	[58,78,22]	3	hSpCas9	negative selection	1489797
166504594	166504617	6	-	26627737	HeLa	viability after 8 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	0.8252559298361113	[414]	[317,299,339]	6	hSpCas9	negative selection	1489798
166508267	166508290	6	-	26627737	HeLa	viability after 8 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.4993359914136897	[1136]	[699,843,563]	4	hSpCas9	negative selection	1489799
166510331	166510354	6	-	26627737	HeLa	viability after 8 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.01733711579755609	[484]	[137,314,173]	0	hSpCas9	negative selection	1489800
166538724	166538747	6	-	26627737	HeLa	viability after 8 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.1914728387617023	[339]	[172,243,95]	1	hSpCas9	negative selection	1489801
166626918	166626941	6	+	26627737	HeLa	viability after 8 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	3.6566053662509326	[11]	[112,44,50]	9	hSpCas9	negative selection	1489802
166498529	166498552	6	-	26627737	HeLa	viability after 12 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	0.5763499970991282	[93]	[12,33,127]	5	hSpCas9	negative selection	1572112
166504594	166504617	6	-	26627737	HeLa	viability after 12 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	0.5978516357628875	[414]	[206,213,360]	5	hSpCas9	negative selection	1572113
166508267	166508290	6	-	26627737	HeLa	viability after 12 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.15030799643906545	[1136]	[513,532,515]	1	hSpCas9	negative selection	1572114
166510331	166510354	6	-	26627737	HeLa	viability after 12 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.14592098063623582	[484]	[152,290,86]	-1	hSpCas9	negative selection	1572115
166538724	166538747	6	-	26627737	HeLa	viability after 12 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-0.01255833289057634	[339]	[246,44,138]	0	hSpCas9	negative selection	1572116
166626918	166626941	6	+	26627737	HeLa	viability after 12 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	3.430725206734879	[11]	[64,88,2]	9	hSpCas9	negative selection	1572117
166498529	166498552	6	-	26627737	HeLa	viability after 15 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	0.6976750005855468	[93]	[9,76,102]	5	hSpCas9	negative selection	1654427
166504594	166504617	6	-	26627737	HeLa	viability after 15 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	1.0349281299007183	[414]	[262,485,285]	7	hSpCas9	negative selection	1654428
166508267	166508290	6	-	26627737	HeLa	viability after 15 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.2509791793760423	[1136]	[705,471,465]	2	hSpCas9	negative selection	1654429
166510331	166510354	6	-	26627737	HeLa	viability after 15 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.20713070155441443	[484]	[291,234,149]	1	hSpCas9	negative selection	1654430
166538724	166538747	6	-	26627737	HeLa	viability after 15 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.013851151943121115	[339]	[136,145,135]	0	hSpCas9	negative selection	1654431
166626918	166626941	6	+	26627737	HeLa	viability after 15 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	4.4113907719139736	[11]	[24,254,26]	9	hSpCas9	negative selection	1654432
166498529	166498552	6	-	26627737	HeLa	viability after 18 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	0.7129372017623434	[93]	[6,64,102]	5	hSpCas9	negative selection	1736742
166504594	166504617	6	-	26627737	HeLa	viability after 18 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	1.0085479772591348	[414]	[162,403,285]	7	hSpCas9	negative selection	1736743
166508267	166508290	6	-	26627737	HeLa	viability after 18 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.26815783750727795	[1136]	[491,383,465]	2	hSpCas9	negative selection	1736744
166510331	166510354	6	-	26627737	HeLa	viability after 18 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.20650784145931528	[484]	[188,202,149]	1	hSpCas9	negative selection	1736745
166538724	166538747	6	-	26627737	HeLa	viability after 18 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.07497238680857984	[339]	[101,122,135]	0	hSpCas9	negative selection	1736746
166626918	166626941	6	+	26627737	HeLa	viability after 18 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	4.426357105685305	[11]	[18,210,26]	9	hSpCas9	negative selection	1736747
166498529	166498552	6	-	26627737	HCT116	viability after 6 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	-0.4218666958808961	[70]	[17,2]	-2	hSpCas9	negative selection	1819057
166504594	166504617	6	-	26627737	HCT116	viability after 6 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-1.1521314359785677	[1395]	[139,75]	-6	hSpCas9	negative selection	1819058
166508267	166508290	6	-	26627737	HCT116	viability after 6 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	-0.6864867518569291	[2154]	[370,121]	-4	hSpCas9	negative selection	1819059
166510331	166510354	6	-	26627737	HCT116	viability after 6 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.6309871714860498	[502]	[81,33]	-4	hSpCas9	negative selection	1819060
166538724	166538747	6	-	26627737	HCT116	viability after 6 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-1.150282619368678	[848]	[63,57]	-6	hSpCas9	negative selection	1819061
166626918	166626941	6	+	26627737	HCT116	viability after 6 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	0.919866522896018	[283]	[68,92]	5	hSpCas9	negative selection	1819062
166498529	166498552	6	-	26627737	HCT116	viability after 8 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	-1.093499374061846	[101]	[18,42,16]	-8	hSpCas9	negative selection	1901372
166504594	166504617	6	-	26627737	HCT116	viability after 8 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-0.022874028333661645	[414]	[218,302,153]	0	hSpCas9	negative selection	1901373
166508267	166508290	6	-	26627737	HCT116	viability after 8 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	-0.12266958282638574	[905]	[530,477,368]	-1	hSpCas9	negative selection	1901374
166510331	166510354	6	-	26627737	HCT116	viability after 8 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.05186988525147682	[296]	[114,128,227]	0	hSpCas9	negative selection	1901375
166538724	166538747	6	-	26627737	HCT116	viability after 8 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-0.34629229836477404	[413]	[218,219,100]	-4	hSpCas9	negative selection	1901376
166626918	166626941	6	+	26627737	HCT116	viability after 8 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	-0.009583505105289492	[119]	[81,20,93]	0	hSpCas9	negative selection	1901377
166498529	166498552	6	-	26627737	HCT116	viability after 9 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	2.348844110843815	[70]	[195,17]	9	hSpCas9	negative selection	1983687
166504594	166504617	6	-	26627737	HCT116	viability after 9 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-1.1654888986943566	[1395]	[111,208]	-7	hSpCas9	negative selection	1983688
166508267	166508290	6	-	26627737	HCT116	viability after 9 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.5532480910897175	[2154]	[568,1061]	4	hSpCas9	negative selection	1983689
166510331	166510354	6	-	26627737	HCT116	viability after 9 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-2.5964687135368907	[502]	[24,19]	-9	hSpCas9	negative selection	1983690
166538724	166538747	6	-	26627737	HCT116	viability after 9 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-1.7448338637188014	[848]	[113,30]	-8	hSpCas9	negative selection	1983691
166626918	166626941	6	+	26627737	HCT116	viability after 9 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	-0.17576121555968172	[283]	[103,37]	-1	hSpCas9	negative selection	1983692
166498529	166498552	6	-	26627737	HCT116	viability after 12 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	-0.03513996301008393	[101]	[105,42,2]	0	hSpCas9	negative selection	2066002
166504594	166504617	6	-	26627737	HCT116	viability after 12 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-0.053794018845129576	[414]	[187,239,204]	0	hSpCas9	negative selection	2066003
166508267	166508290	6	-	26627737	HCT116	viability after 12 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.09960575624098289	[905]	[698,431,380]	1	hSpCas9	negative selection	2066004
166510331	166510354	6	-	26627737	HCT116	viability after 12 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.19259268824351972	[296]	[232,123,171]	2	hSpCas9	negative selection	2066005
166538724	166538747	6	-	26627737	HCT116	viability after 12 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-0.6359858150559394	[413]	[124,84,209]	-6	hSpCas9	negative selection	2066006
166626918	166626941	6	+	26627737	HCT116	viability after 12 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	0.020604827513448498	[119]	[65,74,50]	0	hSpCas9	negative selection	2066007
166498529	166498552	6	-	26627737	HCT116	viability after 15 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	0.2568776406206634	[101]	[100,62,49]	2	hSpCas9	negative selection	2148317
166504594	166504617	6	-	26627737	HCT116	viability after 15 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-0.12905224409989347	[414]	[428,156,94]	-1	hSpCas9	negative selection	2148318
166508267	166508290	6	-	26627737	HCT116	viability after 15 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.1769918364761618	[905]	[924,486,395]	1	hSpCas9	negative selection	2148319
166510331	166510354	6	-	26627737	HCT116	viability after 15 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.10440795021493358	[296]	[247,92,145]	-1	hSpCas9	negative selection	2148320
166538724	166538747	6	-	26627737	HCT116	viability after 15 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-0.46857038412732316	[413]	[221,79,218]	-5	hSpCas9	negative selection	2148321
166626918	166626941	6	+	26627737	HCT116	viability after 15 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	0.35517598043951715	[119]	[94,57,111]	3	hSpCas9	negative selection	2148322
166498529	166498552	6	-	26627737	HCT116	viability after 18 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	-0.2018950478804582	[101]	[52,43,30]	-2	hSpCas9	negative selection	2230632
166504594	166504617	6	-	26627737	HCT116	viability after 18 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	0.49664948847988527	[414]	[429,181,241]	4	hSpCas9	negative selection	2230633
166508267	166508290	6	-	26627737	HCT116	viability after 18 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	-0.13550357718743689	[905]	[516,334,345]	-1	hSpCas9	negative selection	2230634
166510331	166510354	6	-	26627737	HCT116	viability after 18 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.2913846167992574	[296]	[204,147,175]	2	hSpCas9	negative selection	2230635
166538724	166538747	6	-	26627737	HCT116	viability after 18 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-0.7223382611494485	[413]	[97,78,192]	-6	hSpCas9	negative selection	2230636
166626918	166626941	6	+	26627737	HCT116	viability after 18 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	-0.49558534908927676	[119]	[21,9,95]	-4	hSpCas9	negative selection	2230637
166531304	166531327	6	-	24336569	HL60	viability	TTCTCTTGCTAAGGTGTTCCTGG	RPS6KA2	ENSG00000071242	-1.8345493601583793	[449]	[266]	-9	hSpCas9	negative selection	2292968
166538656	166538679	6	+	24336569	HL60	viability	GGCTGAACTTACCTTTCCATAGG	RPS6KA2	ENSG00000071242	-0.36270310184028076	[318]	[524]	-3	hSpCas9	negative selection	2292969
166538667	166538690	6	-	24336569	HL60	viability	AGGACAAGGATCCTATGGAAAGG	RPS6KA2	ENSG00000071242	1.2112157669534223	[577]	[2831]	8	hSpCas9	negative selection	2292970
166538691	166538714	6	+	24336569	HL60	viability	AAACCTTCAGCAGCTCAAACTGG	RPS6KA2	ENSG00000071242	0.06479035829167712	[1030]	[2281]	0	hSpCas9	negative selection	2292971
166538696	166538719	6	+	24336569	HL60	viability	TTCAGCAGCTCAAACTGGGAAGG	RPS6KA2	ENSG00000071242	0.976560946922212	[730]	[3043]	7	hSpCas9	negative selection	2292972
166538724	166538747	6	-	24336569	HL60	viability	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-0.9717718120418105	[1037]	[1119]	-7	hSpCas9	negative selection	2292973
166538730	166538753	6	+	24336569	HL60	viability	CAAAGCCCTCCTTCACATGATGG	RPS6KA2	ENSG00000071242	1.2982276413334906	[234]	[1222]	8	hSpCas9	negative selection	2292974
166538735	166538758	6	-	24336569	HL60	viability	ATCAGCCATCATGTGAAGGAGGG	RPS6KA2	ENSG00000071242	0.3115650612076586	[1543]	[4054]	3	hSpCas9	negative selection	2292975
166538766	166538789	6	-	24336569	HL60	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.6371715156424418	[1599]	[5265]	5	hSpCas9	negative selection	2292976
166538777	166538800	6	-	24336569	HL60	viability	GCCGCTCTCTTGCAGGAAGAAGG	RPS6KA2	ENSG00000071242	0.8125707745412089	[758]	[2820]	6	hSpCas9	negative selection	2292977
166531304	166531327	6	-	24336569	KBM7	viability	TTCTCTTGCTAAGGTGTTCCTGG	RPS6KA2	ENSG00000071242	-0.22828934638857545	[398]	[928]	-2	hSpCas9	negative selection	2360145
166538656	166538679	6	+	24336569	KBM7	viability	GGCTGAACTTACCTTTCCATAGG	RPS6KA2	ENSG00000071242	1.2396214981030114	[319]	[2060]	8	hSpCas9	negative selection	2360146
166538667	166538690	6	-	24336569	KBM7	viability	AGGACAAGGATCCTATGGAAAGG	RPS6KA2	ENSG00000071242	-0.3089103294069191	[1124]	[2476]	-3	hSpCas9	negative selection	2360147
166538691	166538714	6	+	24336569	KBM7	viability	AAACCTTCAGCAGCTCAAACTGG	RPS6KA2	ENSG00000071242	0.8455659977094505	[647]	[3175]	7	hSpCas9	negative selection	2360148
166538696	166538719	6	+	24336569	KBM7	viability	TTCAGCAGCTCAAACTGGGAAGG	RPS6KA2	ENSG00000071242	0.19482840022079456	[557]	[1741]	1	hSpCas9	negative selection	2360149
166538724	166538747	6	-	24336569	KBM7	viability	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.5867777622427788	[777]	[3186]	5	hSpCas9	negative selection	2360150
166538730	166538753	6	+	24336569	KBM7	viability	CAAAGCCCTCCTTCACATGATGG	RPS6KA2	ENSG00000071242	0.02227118735934483	[438]	[1215]	0	hSpCas9	negative selection	2360151
166538735	166538758	6	-	24336569	KBM7	viability	ATCAGCCATCATGTGAAGGAGGG	RPS6KA2	ENSG00000071242	0.42658699327357064	[1298]	[4761]	4	hSpCas9	negative selection	2360152
166538766	166538789	6	-	24336569	KBM7	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.11428490745435571	[1573]	[4646]	1	hSpCas9	negative selection	2360153
166538777	166538800	6	-	24336569	KBM7	viability	GCCGCTCTCTTGCAGGAAGAAGG	RPS6KA2	ENSG00000071242	0.4529248249033253	[648]	[2422]	4	hSpCas9	negative selection	2360154
166453214	166453237	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACACACACACACACACAAAAAG	RPS6KA2	ENSG00000071242	0.9199176005020689	[142,31]	[20,50]	4	dCas9-VP64	positive selection	2387481
166853245	166853268	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTCTCACTATATTGCCTAGG	RPS6KA2	ENSG00000071242	-0.01432879093158157	[84,177]	[14,42]	0	dCas9-VP64	positive selection	2410542
166680080	166680103	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCACTCTGTGTCTAGCTAACGG	RPS6KA2	ENSG00000071242	1.5922584923372158	[90,62]	[91,6]	6	dCas9-VP64	positive selection	2412219
166680039	166680062	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCACTCTGTGTCTAGCTAAAGG	RPS6KA2	ENSG00000071242	1.5922584923372158	[90,62]	[91,6]	6	dCas9-VP64	positive selection	2412228
166454340	166454363	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATACAAAAATTAGCCAGGCGGGG	RPS6KA2	ENSG00000071242	0.7667043826941231	[92,346]	[53,113]	3	dCas9-VP64	positive selection	2426073
166841029	166841052	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAGGCCAAAG	RPS6KA2	ENSG00000071242	-3.2327828351083694	[281,50]	[1,4]	-9	dCas9-VP64	positive selection	2431267
166783129	166783152	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGGCTGGAGTGCAGTGGAGG	RPS6KA2	ENSG00000071242	-1.2921060931449064	[66,2]	[3,0]	-7	dCas9-VP64	positive selection	2435196
166829513	166829536	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCCGCCTCCAGG	RPS6KA2	ENSG00000071242	-0.7325628323231226	[970,485]	[85,105]	-4	dCas9-VP64	positive selection	2435323
166681688	166681711	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGGGGGCGGGGGGGGGGGCGG	RPS6KA2	ENSG00000071242	-1.5649508930732723	[1,29]	[0,0]	-8	dCas9-VP64	positive selection	2439699
166627326	166627349	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAGGAGGTGTGCGTGCCGGGG	RPS6KA2	ENSG00000071242	-1.1309774008873175	[182,95]	[13,12]	-6	dCas9-VP64	positive selection	2452898
166627374	166627397	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGGGTGGTGAGCGCTGATTGG	RPS6KA2	ENSG00000071242	1.7372866714086967	[125,97]	[11,157]	6	dCas9-VP64	positive selection	2452899
166627396	166627419	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTGGTGGTGGGTGGGAACGGG	RPS6KA2	ENSG00000071242	0.8471458490083579	[16,92]	[3,40]	3	dCas9-VP64	positive selection	2452900
166594535	166594558	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCTGCCTCCCGG	RPS6KA2	ENSG00000071242	3.3241346106645673	[178,128]	[9,695]	8	dCas9-VP64	positive selection	2462085
166568378	166568401	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGGTGATCCGCCTGCCTAAG	RPS6KA2	ENSG00000071242	-1.0260640950785338	[143,176]	[21,11]	-6	dCas9-VP64	positive selection	2475161
166453214	166453237	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACACACACACACACACAAAAAG	RPS6KA2	ENSG00000071242	-0.3445413987388147	[115,152]	[39,27]	-3	dCas9-VP64	positive selection	2482736
166853245	166853268	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTCTCACTATATTGCCTAGG	RPS6KA2	ENSG00000071242	-1.4039512164041854	[411,471]	[53,54]	-9	dCas9-VP64	positive selection	2505797
166680080	166680103	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCACTCTGTGTCTAGCTAACGG	RPS6KA2	ENSG00000071242	-0.5532065221327319	[247,247]	[44,63]	-5	dCas9-VP64	positive selection	2507474
166680039	166680062	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCACTCTGTGTCTAGCTAAAGG	RPS6KA2	ENSG00000071242	-0.5532065221327319	[247,247]	[44,63]	-5	dCas9-VP64	positive selection	2507483
166454340	166454363	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATACAAAAATTAGCCAGGCGGGG	RPS6KA2	ENSG00000071242	0.15255249232697954	[139,139]	[73,28]	1	dCas9-VP64	positive selection	2521328
166841029	166841052	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAGGCCAAAG	RPS6KA2	ENSG00000071242	0.5850522226976638	[88,64]	[38,35]	4	dCas9-VP64	positive selection	2526522
166783129	166783152	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGGCTGGAGTGCAGTGGAGG	RPS6KA2	ENSG00000071242	0.4307409852930557	[33,0]	[13,0]	3	dCas9-VP64	positive selection	2530451
166829513	166829536	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCCGCCTCCAGG	RPS6KA2	ENSG00000071242	0.3709996490739482	[598,467]	[394,67]	3	dCas9-VP64	positive selection	2530578
166681688	166681711	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGGGGGCGGGGGGGGGGGCGG	RPS6KA2	ENSG00000071242	0.28293399258432617	[4,5]	[1,1]	2	dCas9-VP64	positive selection	2534954
166627326	166627349	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAGGAGGTGTGCGTGCCGGGG	RPS6KA2	ENSG00000071242	5.440023846447154	[108,86]	[65,2657]	9	dCas9-VP64	positive selection	2548153
166627374	166627397	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGGGTGGTGAGCGCTGATTGG	RPS6KA2	ENSG00000071242	-0.27636151445367974	[30,61]	[7,15]	-3	dCas9-VP64	positive selection	2548154
166627396	166627419	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTGGTGGTGGGTGGGAACGGG	RPS6KA2	ENSG00000071242	0.23714458934056393	[14,47]	[9,12]	2	dCas9-VP64	positive selection	2548155
166594535	166594558	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCTGCCTCCCGG	RPS6KA2	ENSG00000071242	-0.24751078726835885	[128,142]	[21,50]	-2	dCas9-VP64	positive selection	2557340
166568378	166568401	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGGTGATCCGCCTGCCTAAG	RPS6KA2	ENSG00000071242	0.2626572524246065	[103,174]	[69,39]	2	dCas9-VP64	positive selection	2570416
166510278	166510301	6	+	27013184	SW480	treatment with recombinant TRAIL	ATAATGAAGCTTCACAATGAAGG	RPS6KA2	ENSG00000071242	-2.238919399152386	[42,65]	[1,8]	-8	hSpCas9	positive selection	2955121
166538656	166538679	6	+	27013184	SW480	treatment with recombinant TRAIL	GGCTGAACTTACCTTTCCATAGG	RPS6KA2	ENSG00000071242	2.1621328972181826	[744,1107]	[1896,1560]	8	hSpCas9	positive selection	2955122
166510279	166510302	6	+	27013184	SW480	treatment with recombinant TRAIL	TAATGAAGCTTCACAATGAAGGG	RPS6KA2	ENSG00000071242	-1.0605547035230751	[38,11]	[7,1]	-5	hSpCas9	positive selection	2955123
166538691	166538714	6	+	27013184	SW480	treatment with recombinant TRAIL	AAACCTTCAGCAGCTCAAACTGG	RPS6KA2	ENSG00000071242	0.4160740262285185	[322,410]	[102,359]	2	hSpCas9	positive selection	2955124
166531217	166531240	6	+	27013184	SW480	treatment with recombinant TRAIL	TTCCGAAGCTCTTACCTTTTAGG	RPS6KA2	ENSG00000071242	-1.673060595006537	[107,191]	[6,37]	-6	hSpCas9	positive selection	2955125
166531218	166531241	6	+	27013184	SW480	treatment with recombinant TRAIL	TCCGAAGCTCTTACCTTTTAGGG	RPS6KA2	ENSG00000071242	0.7169280752847786	[172,201]	[148,107]	3	hSpCas9	positive selection	2955126
166531221	166531244	6	+	27013184	SW480	treatment with recombinant TRAIL	GAAGCTCTTACCTTTTAGGGTGG	RPS6KA2	ENSG00000071242	1.3620587815440226	[573,652]	[603,779]	6	hSpCas9	positive selection	2955127
166531232	166531255	6	+	27013184	SW480	treatment with recombinant TRAIL	CTTTTAGGGTGGCTTTCTTAAGG	RPS6KA2	ENSG00000071242	-0.45155704863553303	[231,315]	[62,116]	-2	hSpCas9	positive selection	2955128
166538652	166538675	6	-	27013184	SW480	treatment with recombinant TRAIL	TGGAAAGGTAAGTTCAGCCCTGG	RPS6KA2	ENSG00000071242	-0.5301584837521363	[183,164]	[32,79]	-2	hSpCas9	positive selection	2955129
166538667	166538690	6	-	27013184	SW480	treatment with recombinant TRAIL	AGGACAAGGATCCTATGGAAAGG	RPS6KA2	ENSG00000071242	-2.2009409721630804	[119,160]	[5,22]	-7	hSpCas9	positive selection	2955130
166531263	166531286	6	+	27013184	SW480	treatment with recombinant TRAIL	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	1.6661501870163065	[152,217]	[285,198]	7	hSpCas9	positive selection	2955131
166538672	166538695	6	-	27013184	SW480	treatment with recombinant TRAIL	GTTTTAGGACAAGGATCCTATGG	RPS6KA2	ENSG00000071242	-3.246327180214654	[72,65]	[3,1]	-9	hSpCas9	positive selection	2955132
166538681	166538704	6	-	27013184	SW480	treatment with recombinant TRAIL	CTGCTGAAGGTTTTAGGACAAGG	RPS6KA2	ENSG00000071242	0.35001295182417835	[72,112]	[76,11]	1	hSpCas9	positive selection	2955134
166538694	166538717	6	-	27013184	SW480	treatment with recombinant TRAIL	TTCCCAGTTTGAGCTGCTGAAGG	RPS6KA2	ENSG00000071242	-0.5549736793682492	[22,125]	[15,26]	-3	hSpCas9	positive selection	2955136
166510276	166510299	6	-	27013184	SW480	treatment with recombinant TRAIL	TTCATTGTGAAGCTTCATTATGG	RPS6KA2	ENSG00000071242	-0.7633813619632758	[460,651]	[128,153]	-3	hSpCas9	positive selection	2955138
166531210	166531233	6	-	27013184	SW480	treatment with recombinant TRAIL	GGTAAGAGCTTCGGAAGGGCCGG	RPS6KA2	ENSG00000071242	2.6491879437938115	[1,18]	[13,43]	9	hSpCas9	positive selection	2955139
166531219	166531242	6	-	27013184	SW480	treatment with recombinant TRAIL	ACCCTAAAAGGTAAGAGCTTCGG	RPS6KA2	ENSG00000071242	-0.0469260151637525	[581,486]	[132,355]	0	hSpCas9	positive selection	2955140
166510280	166510303	6	+	27013184	SW480	treatment with recombinant TRAIL	AATGAAGCTTCACAATGAAGGGG	RPS6KA2	ENSG00000071242	0.7961827856490538	[10,33]	[25,1]	4	hSpCas9	positive selection	2955141
166538692	166538715	6	+	27013184	SW480	treatment with recombinant TRAIL	AACCTTCAGCAGCTCAAACTGGG	RPS6KA2	ENSG00000071242	0.19634049456745073	[52,94]	[52,10]	1	hSpCas9	positive selection	2955142
166538739	166538762	6	-	27013184	SW480	treatment with recombinant TRAIL	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	0.5053021450083154	[120,197]	[36,178]	2	hSpCas9	positive selection	2955143
166531256	166531279	6	-	27013184	SW480	treatment with recombinant TRAIL	TGGGCAGCTCTACGCCATGAAGG	RPS6KA2	ENSG00000071242	0.33382826241522523	[176,268]	[90,158]	1	hSpCas9	positive selection	2955144
166538777	166538800	6	-	27013184	SW480	treatment with recombinant TRAIL	GCCGCTCTCTTGCAGGAAGAAGG	RPS6KA2	ENSG00000071242	-1.0401037819042398	[444,739]	[69,194]	-5	hSpCas9	positive selection	2955145
166538696	166538719	6	+	27013184	SW480	treatment with recombinant TRAIL	TTCAGCAGCTCAAACTGGGAAGG	RPS6KA2	ENSG00000071242	1.3017060785242953	[63,70]	[68,74]	6	hSpCas9	positive selection	2955146
166538776	166538799	6	+	27013184	SW480	treatment with recombinant TRAIL	GCCTTCTTCCTGCAAGAGAGCGG	RPS6KA2	ENSG00000071242	1.1432674213526104	[217,580]	[409,301]	5	hSpCas9	positive selection	2955148
166538781	166538804	6	+	27013184	SW480	treatment with recombinant TRAIL	CTTCCTGCAAGAGAGCGGCACGG	RPS6KA2	ENSG00000071242	2.5177075853721163	[568,738]	[1514,1714]	9	hSpCas9	positive selection	2955149
166538782	166538805	6	+	27013184	SW480	treatment with recombinant TRAIL	TTCCTGCAAGAGAGCGGCACGGG	RPS6KA2	ENSG00000071242	0.03650270758194685	[147,210]	[90,59]	0	hSpCas9	positive selection	2955150
166500903	166500926	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATCCTCCTGGATGAAGAGGGG	RPS6KA2	ENSG00000071242	0.43117334840703025	[2,3]	[3,3]	8	hSpCas9	positive selection	3017974
166500900	166500923	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTGCCCCTCTTCATCCAGGAGG	RPS6KA2	ENSG00000071242	-0.13710022498916025	[4,4]	[4,2]	-2	hSpCas9	positive selection	3017975
166504597	166504620	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	-0.021406392821131603	[4,3]	[2,3]	0	hSpCas9	positive selection	3017976
166459459	166459482	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGACCCCGAGTTCACAGCGCGG	RPS6KA2	ENSG00000071242	0.0024767673555966957	[3,3]	[4,1]	0	hSpCas9	positive selection	3017977
166500903	166500926	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATCCTCCTGGATGAAGAGGGG	RPS6KA2	ENSG00000071242	0.652323780250925	[2,2]	[3,2]	9	hSpCas9	positive selection	3085832
166500900	166500923	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTGCCCCTCTTCATCCAGGAGG	RPS6KA2	ENSG00000071242	0.5427002505202043	[4,4]	[6,4]	8	hSpCas9	positive selection	3085833
166504597	166504620	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	0.24608718679019326	[4,4]	[3,3]	4	hSpCas9	positive selection	3085834
166459459	166459482	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGACCCCGAGTTCACAGCGCGG	RPS6KA2	ENSG00000071242	-0.12617079154395894	[3,3]	[3,0]	-2	hSpCas9	positive selection	3085835
166531276	166531299		-	24336571	A375	resistance to PLX after 7 days	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.22540495685516054	[15,17]	[20,18]	6	hSpCas9	positive selection	3141889
166538667	166538690		-	24336571	A375	resistance to PLX after 7 days	AGGACAAGGATCCTATGGAAAGG	RPS6KA2	ENSG00000071242	0.16306947872429278	[5,6]	[5,7]	5	hSpCas9	positive selection	3141890
166538766	166538789		-	24336571	A375	resistance to PLX after 7 days	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.0901082511746919	[20,27]	[20,24]	-3	hSpCas9	positive selection	3141891
166531263	166531286		+	24336571	A375	resistance to PLX after 7 days	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.1379951475620086	[12,12]	[11,11]	-4	hSpCas9	positive selection	3141892
166531276	166531299		-	24336571	A375	resistance to PLX after 14 days	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.6585844907366921	[15,11]	[11,7]	6	hSpCas9	positive selection	3199682
166538667	166538690		-	24336571	A375	resistance to PLX after 14 days	AGGACAAGGATCCTATGGAAAGG	RPS6KA2	ENSG00000071242	0.6325509232504549	[8,4]	[5,3]	5	hSpCas9	positive selection	3199683
166538766	166538789		-	24336571	A375	resistance to PLX after 14 days	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.2945458066053229	[21,24]	[8,7]	-3	hSpCas9	positive selection	3199684
166531263	166531286		+	24336571	A375	resistance to PLX after 14 days	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.10036912828469613	[7,8]	[3,2]	-1	hSpCas9	positive selection	3199685
166531276	166531299		-	24336571	A375	viability after 7 days	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.32043164603896573	[13]	[15,17]	5	hSpCas9	negative selection	3257475
166538667	166538690		-	24336571	A375	viability after 7 days	AGGACAAGGATCCTATGGAAAGG	RPS6KA2	ENSG00000071242	-0.5013933719056078	[9]	[5,6]	-6	hSpCas9	negative selection	3257476
166538766	166538789		-	24336571	A375	viability after 7 days	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.23264444698255216	[21]	[20,27]	3	hSpCas9	negative selection	3257477
166531263	166531286		+	24336571	A375	viability after 7 days	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	0.28539251846399083	[10]	[12,12]	4	hSpCas9	negative selection	3257478
166531276	166531299		-	24336571	A375	viability after 14 days	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.05352534862077797	[13]	[15,11]	0	hSpCas9	negative selection	3315268
166538667	166538690		-	24336571	A375	viability after 14 days	AGGACAAGGATCCTATGGAAAGG	RPS6KA2	ENSG00000071242	-0.31465894404859834	[9]	[8,4]	-4	hSpCas9	negative selection	3315269
166538766	166538789		-	24336571	A375	viability after 14 days	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.1764075492792806	[21]	[21,24]	2	hSpCas9	negative selection	3315270
166531263	166531286		+	24336571	A375	viability after 14 days	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.31041610503808104	[10]	[7,8]	-4	hSpCas9	negative selection	3315271
166538766	166538789	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.7027373597681978	[93,93]	[0,0]	3	hSpCas9	positive selection	3390667
166510328	166510351	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	-1.2102793386371622	[707,707]	[1,1]	-7	hSpCas9	positive selection	3390668
166538739	166538762	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.25046842875286124	[181,181]	[0,0]	-1	hSpCas9	positive selection	3390669
166500903	166500926	6	-	26780180	HT29	viability (Avana library 4 designs)	GCATCCTCCTGGATGAAGAGGGG	RPS6KA2	ENSG00000071242	0.818266012457459	[]	[]	3	hSpCas9	negative selection	3456355
166500899	166500922	6	+	26780180	HT29	viability (Avana library 4 designs)	TGTGCCCCTCTTCATCCAGGAGG	RPS6KA2	ENSG00000071242	0.62079652884241	[]	[]	2	hSpCas9	negative selection	3456356
166504597	166504620	6	-	26780180	HT29	viability (Avana library 4 designs)	TTACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	1.90700211104913	[]	[]	7	hSpCas9	negative selection	3456357
166459459	166459482	6	-	26780180	HT29	viability (Avana library 4 designs)	TTGACCCCGAGTTCACAGCGCGG	RPS6KA2	ENSG00000071242	0.530686193509241	[]	[]	2	hSpCas9	negative selection	3456358
166504597	166504620	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	-1.02646919957303	[]	[]	-1	hSpCas9	negative selection	3554792
166459459	166459482	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGACCCCGAGTTCACAGCGCGG	RPS6KA2	ENSG00000071242	4.06815500627365	[]	[]	6	hSpCas9	negative selection	3554793
166500903	166500926	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATCCTCCTGGATGAAGAGGGG	RPS6KA2	ENSG00000071242	5.57135925322722	[]	[]	8	hSpCas9	negative selection	3554794
166500899	166500922	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGCCCCTCTTCATCCAGGAGG	RPS6KA2	ENSG00000071242	1.58009456879317	[]	[]	2	hSpCas9	negative selection	3554795
166510331	166510354	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	1.06727110209437	[]	[]	1	hSpCas9	negative selection	3554796
166451198	166451221	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGAGCGTTTGCACTCGGGGGG	RPS6KA2	ENSG00000071242	2.53027614523806	[]	[]	4	hSpCas9	negative selection	3554797
166504597	166504620	6	-	26780180	A375	viability (Avana lentiGuide)	TTACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	3.62716978516011	[]	[]	3	hSpCas9	negative selection	3663451
166459459	166459482	6	-	26780180	A375	viability (Avana lentiGuide)	TTGACCCCGAGTTCACAGCGCGG	RPS6KA2	ENSG00000071242	0.214699258503562	[]	[]	0	hSpCas9	negative selection	3663452
166500903	166500926	6	-	26780180	A375	viability (Avana lentiGuide)	GCATCCTCCTGGATGAAGAGGGG	RPS6KA2	ENSG00000071242	-0.00206331502005247	[]	[]	0	hSpCas9	negative selection	3663453
166500899	166500922	6	+	26780180	A375	viability (Avana lentiGuide)	TGTGCCCCTCTTCATCCAGGAGG	RPS6KA2	ENSG00000071242	-1.96335945540861	[]	[]	-3	hSpCas9	negative selection	3663454
166510331	166510354	6	-	26780180	A375	viability (Avana lentiGuide)	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-2.78297727304069	[]	[]	-5	hSpCas9	negative selection	3663455
166451198	166451221	6	+	26780180	A375	viability (Avana lentiGuide)	GATGAGCGTTTGCACTCGGGGGG	RPS6KA2	ENSG00000071242	0.994982396522327	[]	[]	1	hSpCas9	negative selection	3663456
166504597	166504620	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	-0.30952733906821506	[5]	[4,3]	-5	hSpCas9	positive selection	3772058
166459459	166459482	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGACCCCGAGTTCACAGCGCGG	RPS6KA2	ENSG00000071242	0.17239595493722742	[4]	[5,4]	5	hSpCas9	positive selection	3772059
166500903	166500926	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATCCTCCTGGATGAAGAGGGG	RPS6KA2	ENSG00000071242	0.14716233539842316	[4]	[4,4]	4	hSpCas9	positive selection	3772060
166500899	166500922	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGCCCCTCTTCATCCAGGAGG	RPS6KA2	ENSG00000071242	0.03908244050752868	[6]	[6,5]	1	hSpCas9	positive selection	3772061
166510331	166510354	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.09985951044907657	[5]	[6,5]	2	hSpCas9	positive selection	3772062
166451198	166451221	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGAGCGTTTGCACTCGGGGGG	RPS6KA2	ENSG00000071242	0.30105649522836075	[4]	[5,5]	8	hSpCas9	positive selection	3772063
166504597	166504620	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	0.06958713620750152	[5]	[4,5]	1	hSpCas9	positive selection	3880665
166459459	166459482	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGACCCCGAGTTCACAGCGCGG	RPS6KA2	ENSG00000071242	-0.04020325250972835	[5]	[3,4]	0	hSpCas9	positive selection	3880666
166500903	166500926	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATCCTCCTGGATGAAGAGGGG	RPS6KA2	ENSG00000071242	-0.09095074294155012	[4]	[1,5]	-1	hSpCas9	positive selection	3880667
166500899	166500922	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGCCCCTCTTCATCCAGGAGG	RPS6KA2	ENSG00000071242	0.2856359019654005	[6]	[7,7]	7	hSpCas9	positive selection	3880668
166510331	166510354	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.3333452293892615	[6]	[6,6]	8	hSpCas9	positive selection	3880669
166451198	166451221	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGAGCGTTTGCACTCGGGGGG	RPS6KA2	ENSG00000071242	-0.6377837345253601	[4]	[1,3]	-7	hSpCas9	positive selection	3880670
166531276	166531299	6	-	26780180	A375	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.650966338711083	[]	[]	2	hSpCas9	negative selection	3990689
166538739	166538762	6	-	26780180	A375	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	0.963256128461606	[]	[]	4	hSpCas9	negative selection	3990690
166538766	166538789	6	-	26780180	A375	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.92621604878184	[]	[]	4	hSpCas9	negative selection	3990691
166510331	166510354	6	-	26780180	A375	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.910538447915156	[]	[]	4	hSpCas9	negative selection	3990692
166531263	166531286	6	+	26780180	A375	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	0.746613054561196	[]	[]	2	hSpCas9	negative selection	3990693
166510328	166510351	6	+	26780180	A375	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.520914274385835	[]	[]	1	hSpCas9	negative selection	3990694
166531276	166531299	6	-	26780180	HT29	viability (GeCKOv2 library)	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.465617289499214	[]	[]	1	hSpCas9	negative selection	4098655
166538739	166538762	6	-	26780180	HT29	viability (GeCKOv2 library)	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	1.29904251917702	[]	[]	6	hSpCas9	negative selection	4098656
166538766	166538789	6	-	26780180	HT29	viability (GeCKOv2 library)	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	1.06287120910564	[]	[]	5	hSpCas9	negative selection	4098657
166510331	166510354	6	-	26780180	HT29	viability (GeCKOv2 library)	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.81476369155903	[]	[]	3	hSpCas9	negative selection	4098658
166531263	166531286	6	+	26780180	HT29	viability (GeCKOv2 library)	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	1.06336933500688	[]	[]	5	hSpCas9	negative selection	4098659
166510328	166510351	6	+	26780180	HT29	viability (GeCKOv2 library)	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	-0.212654792161991	[]	[]	-6	hSpCas9	negative selection	4098660
166531276	166531299	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.037365441218003406	[3]	[1,3]	0	hSpCas9	positive selection	4167576
166538667	166538690	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGACAAGGATCCTATGGAAAGG	RPS6KA2	ENSG00000071242	-0.12209416901557563	[2]	[1,2]	-3	hSpCas9	positive selection	4167577
166538766	166538789	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.04971074775376649	[4]	[2,2]	1	hSpCas9	positive selection	4167578
166531263	166531286	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.14744411800166587	[2]	[1,1]	-3	hSpCas9	positive selection	4167579
166531276	166531299	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	1.2469063358416743	[3]	[3,2,2,4]	9	hSpCas9	positive selection	4231598
166538667	166538690	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGACAAGGATCCTATGGAAAGG	RPS6KA2	ENSG00000071242	1.3470583388158865	[2]	[0,4,2,3]	9	hSpCas9	positive selection	4231599
166538766	166538789	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.24210225534891258	[3]	[3,2,2,0]	2	hSpCas9	positive selection	4231600
166531263	166531286	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.11038627599236212	[2]	[1,0,1,0]	-1	hSpCas9	positive selection	4231601
166531276	166531299	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.13624603206462993	[0]	[0,0]	-3	hSpCas9	positive selection	4295792
166510331	166510354	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.36159574860707866	[1]	[3,0]	7	hSpCas9	positive selection	4295793
166531263	166531286	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	0.22806047391712786	[1]	[1,1]	4	hSpCas9	positive selection	4295794
166538766	166538789	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.013581419708593612	[1]	[2,0]	0	hSpCas9	positive selection	4360045
166510328	166510351	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.4652438518215869	[4]	[5,4]	8	hSpCas9	positive selection	4360046
166538739	166538762	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.4707382348445153	[2]	[2,0]	-8	hSpCas9	positive selection	4360047
166498567	166498589	6	-	27760321	OCIAML3	viability	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	0.127527672189941	[1033,906]	[770,900]	1	hSpCas9	negative selection	4435948
166504597	166504619	6	-	27760321	OCIAML3	viability	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	0.5798537549940621	[371,367]	[441,422]	7	hSpCas9	negative selection	4435949
166451207	166451229	6	+	27760321	OCIAML3	viability	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	0.13500222252812394	[550,520]	[399,539]	1	hSpCas9	negative selection	4435950
166459456	166459478	6	+	27760321	OCIAML3	viability	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	0.1543569810345677	[517,582]	[433,546]	1	hSpCas9	negative selection	4435951
166459536	166459558	6	-	27760321	OCIAML3	viability	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	0.028854262256870933	[842,646]	[480,731]	0	hSpCas9	negative selection	4435952
166498567	166498589	6	-	27760321	OCIAML2	viability	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	0.4465148351141177	[1033,906]	[992,1165]	6	hSpCas9	negative selection	4519411
166504597	166504619	6	-	27760321	OCIAML2	viability	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	0.18465861576981635	[371,367]	[297,397]	2	hSpCas9	negative selection	4519412
166451207	166451229	6	+	27760321	OCIAML2	viability	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	0.4707783409619468	[550,520]	[610,588]	6	hSpCas9	negative selection	4519413
166459456	166459478	6	+	27760321	OCIAML2	viability	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	0.6689600667255579	[517,582]	[658,785]	8	hSpCas9	negative selection	4519414
166459536	166459558	6	-	27760321	OCIAML2	viability	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	-0.606965586285312	[842,646]	[327,477]	-6	hSpCas9	negative selection	4519415
166498567	166498589	6	-	27760321	MV411	viability	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	0.5114390190267448	[1033,906]	[687,1245]	3	hSpCas9	negative selection	4602874
166504597	166504619	6	-	27760321	MV411	viability	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	1.0728382465287591	[371,367]	[602,382]	7	hSpCas9	negative selection	4602875
166451207	166451229	6	+	27760321	MV411	viability	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	0.22578051077211092	[550,520]	[216,709]	1	hSpCas9	negative selection	4602876
166459456	166459478	6	+	27760321	MV411	viability	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	1.2659397456370027	[517,582]	[1026,660]	8	hSpCas9	negative selection	4602877
166459536	166459558	6	-	27760321	MV411	viability	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	-0.6553155804122506	[842,646]	[316,298]	-4	hSpCas9	negative selection	4602878
166498567	166498589	6	-	27760321	HL60	viability	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	-0.029507025983729784	[1033,906]	[728,823]	0	hSpCas9	negative selection	4686337
166504597	166504619	6	-	27760321	HL60	viability	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	0.05135946631376445	[371,367]	[316,310]	0	hSpCas9	negative selection	4686338
166451207	166451229	6	+	27760321	HL60	viability	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	0.33889895077305243	[550,520]	[614,489]	4	hSpCas9	negative selection	4686339
166459456	166459478	6	+	27760321	HL60	viability	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	0.8336868706045905	[517,582]	[922,685]	8	hSpCas9	negative selection	4686340
166459536	166459558	6	-	27760321	HL60	viability	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	-0.6795058960518741	[842,646]	[430,319]	-6	hSpCas9	negative selection	4686341
166498567	166498589	6	-	27760321	HT1080	viability	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	0.17382450023883278	[906,707]	[275,457]	0	hSpCas9	negative selection	4769800
166504597	166504619	6	-	27760321	HT1080	viability	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	1.3795400788562657	[367,286]	[158,536]	7	hSpCas9	negative selection	4769801
166451207	166451229	6	+	27760321	HT1080	viability	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	0.24284047724770458	[520,406]	[265,166]	1	hSpCas9	negative selection	4769802
166459456	166459478	6	+	27760321	HT1080	viability	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	0.08294653356303838	[582,454]	[281,149]	0	hSpCas9	negative selection	4769803
166459536	166459558	6	-	27760321	HT1080	viability	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	0.7767180767622099	[646,504]	[342,447]	4	hSpCas9	negative selection	4769804
166498567	166498589	6	-	27760321	HT29	viability after 7 days	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	0.1502650798889511	[906,707]	[1183,1140,1134]	2	hSpCas9	negative selection	4853263
166504597	166504619	6	-	27760321	HT29	viability after 7 days	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	-0.14347070728480202	[367,286]	[456,288,406]	-2	hSpCas9	negative selection	4853264
166451207	166451229	6	+	27760321	HT29	viability after 7 days	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	0.5858695242995737	[520,406]	[681,1023,946]	8	hSpCas9	negative selection	4853265
166459456	166459478	6	+	27760321	HT29	viability after 7 days	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	-0.26182160927388026	[582,454]	[583,254,824]	-4	hSpCas9	negative selection	4853266
166459536	166459558	6	-	27760321	HT29	viability after 7 days	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	-0.4525636109078295	[646,504]	[539,332,742]	-6	hSpCas9	negative selection	4853267
166498567	166498589	6	-	27760321	HT29	viability after 25 days	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	0.4853500911389903	[906,707]	[843,1808,1243]	5	hSpCas9	negative selection	4936726
166504597	166504619	6	-	27760321	HT29	viability after 25 days	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	0.2241784958947497	[367,286]	[468,366,476]	2	hSpCas9	negative selection	4936727
166451207	166451229	6	+	27760321	HT29	viability after 25 days	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	0.1660009211479389	[520,406]	[550,612,625]	1	hSpCas9	negative selection	4936728
166459456	166459478	6	+	27760321	HT29	viability after 25 days	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	0.029631655090997966	[582,454]	[475,582,782]	0	hSpCas9	negative selection	4936729
166459536	166459558	6	-	27760321	HT29	viability after 25 days	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	-0.597545829302064	[646,504]	[326,447,547]	-5	hSpCas9	negative selection	4936730
166498567	166498589	6	-	27760321	HT29	viability after 22 days	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	0.5529298151829793	[906,707]	[1403,1501,1199]	6	hSpCas9	negative selection	5020189
166504597	166504619	6	-	27760321	HT29	viability after 22 days	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	0.17334641893990188	[367,286]	[729,278,261]	1	hSpCas9	negative selection	5020190
166451207	166451229	6	+	27760321	HT29	viability after 22 days	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	0.33852522505669863	[520,406]	[660,837,534]	3	hSpCas9	negative selection	5020191
166459456	166459478	6	+	27760321	HT29	viability after 22 days	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	0.10609308114168658	[582,454]	[435,752,754]	1	hSpCas9	negative selection	5020192
166459536	166459558	6	-	27760321	HT29	viability after 22 days	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	-0.2920588648999758	[646,504]	[430,616,586]	-3	hSpCas9	negative selection	5020193
166498567	166498589	6	-	27760321	HT29	viability after 19 days	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	0.7833619402490339	[906,707]	[1098,1380,2211]	7	hSpCas9	negative selection	5103652
166504597	166504619	6	-	27760321	HT29	viability after 19 days	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	-0.5738756968413105	[367,286]	[362,222,182]	-5	hSpCas9	negative selection	5103653
166451207	166451229	6	+	27760321	HT29	viability after 19 days	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	0.25778934536944814	[520,406]	[697,448,757]	2	hSpCas9	negative selection	5103654
166459456	166459478	6	+	27760321	HT29	viability after 19 days	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	0.15674992632475482	[582,454]	[805,565,628]	1	hSpCas9	negative selection	5103655
166459536	166459558	6	-	27760321	HT29	viability after 19 days	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	-0.4225448963125202	[646,504]	[662,601,236]	-4	hSpCas9	negative selection	5103656
166498567	166498589	6	-	27760321	HT29	viability after 16 days	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	0.656256038230457	[906,707]	[1638,1329,1324]	7	hSpCas9	negative selection	5187115
166504597	166504619	6	-	27760321	HT29	viability after 16 days	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	0.3228505336837023	[367,286]	[680,297,420]	3	hSpCas9	negative selection	5187116
166451207	166451229	6	+	27760321	HT29	viability after 16 days	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	0.5988322035404243	[520,406]	[589,904,841]	7	hSpCas9	negative selection	5187117
166459456	166459478	6	+	27760321	HT29	viability after 16 days	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	0.08666759541929725	[582,454]	[609,658,578]	0	hSpCas9	negative selection	5187118
166459536	166459558	6	-	27760321	HT29	viability after 16 days	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	-0.4144724237774456	[646,504]	[658,446,361]	-4	hSpCas9	negative selection	5187119
166498567	166498589	6	-	27760321	HT29	viability after 13 days	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	0.48581836867433714	[906,707]	[1449,1342,1151]	6	hSpCas9	negative selection	5270578
166504597	166504619	6	-	27760321	HT29	viability after 13 days	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	-0.22943567691282094	[367,286]	[323,253,389]	-3	hSpCas9	negative selection	5270579
166451207	166451229	6	+	27760321	HT29	viability after 13 days	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	0.3687907971198469	[520,406]	[778,371,919]	4	hSpCas9	negative selection	5270580
166459456	166459478	6	+	27760321	HT29	viability after 13 days	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	-0.3600543817614607	[582,454]	[527,356,518]	-4	hSpCas9	negative selection	5270581
166459536	166459558	6	-	27760321	HT29	viability after 13 days	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	-0.20330487468407377	[646,504]	[538,618,582]	-2	hSpCas9	negative selection	5270582
166498567	166498589	6	-	27760321	HT29	viability after 10 days	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	0.18501737184920852	[906,707]	[957,1363,1122]	2	hSpCas9	negative selection	5354041
166504597	166504619	6	-	27760321	HT29	viability after 10 days	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	0.05140587715324453	[367,286]	[553,403,314]	0	hSpCas9	negative selection	5354042
166451207	166451229	6	+	27760321	HT29	viability after 10 days	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	-0.06423718466065093	[520,406]	[411,791,466]	-1	hSpCas9	negative selection	5354043
166459456	166459478	6	+	27760321	HT29	viability after 10 days	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	-0.43348682347393336	[582,454]	[452,503,482]	-5	hSpCas9	negative selection	5354044
166459536	166459558	6	-	27760321	HT29	viability after 10 days	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	-0.564186848153061	[646,504]	[591,596,277]	-6	hSpCas9	negative selection	5354045
166498567	166498589	6	-	27760321	MOLM13	viability	ATCGAGTACATGGCGCCCGAGG	RPS6KA2	ENSG00000071242	0.4862380705585607	[1033,906]	[490,998]	3	hSpCas9	negative selection	5437504
166504597	166504619	6	-	27760321	MOLM13	viability	TACTAGGTCATGTTCACGGAGG	RPS6KA2	ENSG00000071242	-0.215794115954147	[371,367]	[243,125]	-1	hSpCas9	negative selection	5437505
166451207	166451229	6	+	27760321	MOLM13	viability	TTGCACTCGGGGGGACGCCAGG	RPS6KA2	ENSG00000071242	0.33036411776253927	[550,520]	[506,272]	2	hSpCas9	negative selection	5437506
166459456	166459478	6	+	27760321	MOLM13	viability	CGTCCGCGCTGTGAACTCGGGG	RPS6KA2	ENSG00000071242	0.6712878539741992	[517,582]	[321,648]	4	hSpCas9	negative selection	5437507
166459536	166459558	6	-	27760321	MOLM13	viability	TAATAGACGCTGTACCGGAAGG	RPS6KA2	ENSG00000071242	-0.3082792083397975	[842,646]	[586,123]	-2	hSpCas9	negative selection	5437508
166626824	166626847	6	+	27661255	K562	viability	GGGTCTCGGGGTCCACCCAGGGG	RPS6KA2	ENSG00000071242	-0.8964438807186473	[833,1167]	[494,368]	-8	dCas9-KRAB	negative selection	5508622
166627121	166627144	6	+	27661255	K562	viability	GAGCCCGGCACGGCGGCCATGGG	RPS6KA2	ENSG00000071242	-0.020405531284911516	[438,541]	[413,359]	-1	dCas9-KRAB	negative selection	5508623
166627157	166627180	6	+	27661255	K562	viability	GCGCGAGCTGCGGTCACAAAGGG	RPS6KA2	ENSG00000071242	0.16817163060036977	[192,247]	[189,202]	6	dCas9-KRAB	negative selection	5508624
166626817	166626840	6	-	27661255	K562	viability	GTGGACCCCGAGACCCGTCAGGG	RPS6KA2	ENSG00000071242	0.06926121817223552	[1431,1315]	[1169,1138]	2	dCas9-KRAB	negative selection	5508625
166627238	166627261	6	-	27661255	K562	viability	GGCGCTGGTACTCGCAGGGGAGG	RPS6KA2	ENSG00000071242	0.1366982804557435	[346,338]	[316,287]	5	dCas9-KRAB	negative selection	5508626
166627241	166627264	6	-	27661255	K562	viability	GCCGGCGCTGGTACTCGCAGGGG	RPS6KA2	ENSG00000071242	0.3900614762190248	[418,583]	[604,450]	9	dCas9-KRAB	negative selection	5508627
166531276	166531299	6	-	27260156	BXPC3	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.9864021407347021	[51]	[109,45,52,239]	9	hSpCas9	negative selection	5568252
166510331	166510354	6	-	27260156	BXPC3	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.41419913314204493	[169]	[280,151,265,248]	8	hSpCas9	negative selection	5568253
166531263	166531286	6	+	27260156	BXPC3	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	0.012796464728423551	[113]	[111,101,120,150]	0	hSpCas9	negative selection	5568254
166538766	166538789	6	-	27260156	BXPC3	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.05823443901390912	[186]	[148,172,208,301]	1	hSpCas9	negative selection	5632505
166510328	166510351	6	+	27260156	BXPC3	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.15252220902979352	[1414]	[1410,1604,1702,1908]	3	hSpCas9	negative selection	5632506
166538739	166538762	6	-	27260156	BXPC3	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.12525661086330142	[443]	[394,373,384,568]	-3	hSpCas9	negative selection	5632507
166531276	166531299	6	-	27260156	A673	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.20664845741553473	[51]	[100,83,69,33]	5	hSpCas9	negative selection	5689503
166510331	166510354	6	-	27260156	A673	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.22757871842041988	[169]	[287,223,222,225]	5	hSpCas9	negative selection	5689504
166531263	166531286	6	+	27260156	A673	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.07802617324177108	[113]	[135,120,108,154]	-2	hSpCas9	negative selection	5689505
166538766	166538789	6	-	27260156	A673	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.036459653561524474	[186]	[221,201,223,274]	0	hSpCas9	negative selection	5753756
166510328	166510351	6	+	27260156	A673	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.3201518513023074	[1414]	[2465,2070,2009,1966]	7	hSpCas9	negative selection	5753757
166538739	166538762	6	-	27260156	A673	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.24906248866401604	[443]	[473,385,425,515]	-6	hSpCas9	negative selection	5753758
166531276	166531299	6	-	27260156	A375	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.10001937884024192	[51]	[29,116,61,28]	-1	hSpCas9	negative selection	5810754
166510331	166510354	6	-	27260156	A375	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.20782430249301798	[169]	[159,410,277,106]	3	hSpCas9	negative selection	5810755
166531263	166531286	6	+	27260156	A375	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	0.28772133314055437	[113]	[280,209,95,79]	4	hSpCas9	negative selection	5810756
166538766	166538789	6	-	27260156	A375	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.67052749145569	[186]	[358,345,455,240]	8	hSpCas9	negative selection	5875007
166510328	166510351	6	+	27260156	A375	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.5228035734787977	[1414]	[2587,2671,2324,1992]	7	hSpCas9	negative selection	5875008
166538739	166538762	6	-	27260156	A375	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.33447336757897445	[443]	[299,566,502,306]	-5	hSpCas9	negative selection	5875009
166531276	166531299	6	-	27260156	COLO741	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.4851971860732256	[51]	[164,71,50]	8	hSpCas9	negative selection	5932005
166510331	166510354	6	-	27260156	COLO741	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.06451123301878114	[169]	[297,233,105]	-1	hSpCas9	negative selection	5932006
166531263	166531286	6	+	27260156	COLO741	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	0.04967807348767783	[113]	[133,157,157]	1	hSpCas9	negative selection	5932007
166538766	166538789	6	-	27260156	COLO741	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.051978349809446156	[186]	[208,277,251]	1	hSpCas9	negative selection	5996258
166510328	166510351	6	+	27260156	COLO741	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.4274895822570126	[1414]	[2740,2578,2025]	8	hSpCas9	negative selection	5996259
166538739	166538762	6	-	27260156	COLO741	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.34149923160221113	[443]	[492,475,381]	-6	hSpCas9	negative selection	5996260
166531276	166531299	6	-	27260156	CAL120	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.8641350121445655	[51]	[188,111,63]	9	hSpCas9	negative selection	6053256
166510331	166510354	6	-	27260156	CAL120	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.9395117914362743	[169]	[849,260,176]	9	hSpCas9	negative selection	6053257
166531263	166531286	6	+	27260156	CAL120	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-1.016847305473937	[113]	[36,24,141]	-8	hSpCas9	negative selection	6053258
166538766	166538789	6	-	27260156	CAL120	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.11090942104420609	[186]	[251,200,299]	1	hSpCas9	negative selection	6117509
166510328	166510351	6	+	27260156	CAL120	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.4362422801935535	[1414]	[2525,2308,2333]	6	hSpCas9	negative selection	6117510
166538739	166538762	6	-	27260156	CAL120	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	0.050998754907910365	[443]	[980,425,374]	0	hSpCas9	negative selection	6117511
166531276	166531299	6	-	27260156	CADOES1	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.1079814004001407	[51]	[40,74,7,55]	-2	hSpCas9	negative selection	6174507
166510331	166510354	6	-	27260156	CADOES1	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.0018136107176842664	[169]	[249,112,134,133]	0	hSpCas9	negative selection	6174508
166531263	166531286	6	+	27260156	CADOES1	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.22820910862434918	[113]	[81,81,108,88]	-4	hSpCas9	negative selection	6174509
166538766	166538789	6	-	27260156	CADOES1	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.17205047371179583	[186]	[144,240,145,82]	-3	hSpCas9	negative selection	6238760
166510328	166510351	6	+	27260156	CADOES1	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.39914482555835273	[1414]	[1610,1730,1742,1861]	6	hSpCas9	negative selection	6238761
166538739	166538762	6	-	27260156	CADOES1	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.2047202334008093	[443]	[366,198,428,440]	-4	hSpCas9	negative selection	6238762
166531276	166531299	6	-	27260156	EWS502	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.3986549816906	[51]	[50,29,32,52]	-6	hSpCas9	negative selection	6295758
166510331	166510354	6	-	27260156	EWS502	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.28786433284263224	[169]	[118,301,225,241]	5	hSpCas9	negative selection	6295759
166531263	166531286	6	+	27260156	EWS502	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.4174554980154972	[113]	[78,68,109,106]	-6	hSpCas9	negative selection	6295760
166538766	166538789	6	-	27260156	EWS502	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.218582351251142	[186]	[128,143,200,215]	-4	hSpCas9	negative selection	6360011
166510328	166510351	6	+	27260156	EWS502	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.4035894424971658	[1414]	[1921,2002,1787,2230]	7	hSpCas9	negative selection	6360012
166538739	166538762	6	-	27260156	EWS502	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.21368432649517766	[443]	[510,316,360,422]	-4	hSpCas9	negative selection	6360013
166531276	166531299	6	-	27260156	EW8	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.6491588708535216	[51]	[75,70,85,28]	9	hSpCas9	negative selection	6417009
166510331	166510354	6	-	27260156	EW8	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.11819151283921081	[169]	[155,147,103,197]	2	hSpCas9	negative selection	6417010
166531263	166531286	6	+	27260156	EW8	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.5479698781189248	[113]	[108,47,42,60]	-7	hSpCas9	negative selection	6417011
166538766	166538789	6	-	27260156	EW8	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.13980660396707756	[186]	[203,201,117,155]	2	hSpCas9	negative selection	6481262
166510328	166510351	6	+	27260156	EW8	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.42207304526371137	[1414]	[2026,1583,1254,1377]	7	hSpCas9	negative selection	6481263
166538739	166538762	6	-	27260156	EW8	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.26287812480446743	[443]	[385,294,223,315]	-5	hSpCas9	negative selection	6481264
166531276	166531299	6	-	27260156	CORL105	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.6996513103384814	[51]	[60,111,168,62]	9	hSpCas9	negative selection	6538260
166510331	166510354	6	-	27260156	CORL105	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.3805084098053615	[169]	[218,247,459,139]	7	hSpCas9	negative selection	6538261
166531263	166531286	6	+	27260156	CORL105	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.32251304853892293	[113]	[112,63,151,105]	-5	hSpCas9	negative selection	6538262
166538766	166538789	6	-	27260156	CORL105	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.08963563834979271	[186]	[241,291,206,185]	1	hSpCas9	negative selection	6602513
166510328	166510351	6	+	27260156	CORL105	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.10338520533857065	[1414]	[1652,1892,1997,1601]	2	hSpCas9	negative selection	6602514
166538739	166538762	6	-	27260156	CORL105	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.2435103391188977	[443]	[363,371,468,553]	-4	hSpCas9	negative selection	6602515
166531276	166531299	6	-	27260156	HS294T	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.644412849081414	[51]	[48,30,11,31]	8	hSpCas9	negative selection	6659511
166510331	166510354	6	-	27260156	HS294T	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.3517607162842695	[169]	[39,84,132,80]	5	hSpCas9	negative selection	6659512
166531263	166531286	6	+	27260156	HS294T	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.5531993901117431	[113]	[40,14,40,20]	-7	hSpCas9	negative selection	6659513
166538766	166538789	6	-	27260156	HS294T	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.47226103858013935	[186]	[28,57,82,37]	-6	hSpCas9	negative selection	6723764
166510328	166510351	6	+	27260156	HS294T	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.34378831169656454	[1414]	[771,573,688,744]	4	hSpCas9	negative selection	6723765
166538739	166538762	6	-	27260156	HS294T	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.15316769197084876	[443]	[134,105,177,210]	-2	hSpCas9	negative selection	6723766
166531276	166531299	6	-	27260156	HCC44	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.5635480168889289	[51]	[37,28,75,23]	-7	hSpCas9	negative selection	6780762
166510331	166510354	6	-	27260156	HCC44	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.061268185459340874	[169]	[283,190,205,131]	0	hSpCas9	negative selection	6780763
166531263	166531286	6	+	27260156	HCC44	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.3101509506998119	[113]	[59,120,138,94]	-5	hSpCas9	negative selection	6780764
166538766	166538789	6	-	27260156	HCC44	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.44442745210868084	[186]	[176,240,420,327]	7	hSpCas9	negative selection	6845015
166510328	166510351	6	+	27260156	HCC44	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.3241431617733066	[1414]	[1972,1684,2479,1984]	5	hSpCas9	negative selection	6845016
166538739	166538762	6	-	27260156	HCC44	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.13360370105661834	[443]	[546,299,503,512]	-2	hSpCas9	negative selection	6845017
166531276	166531299	6	-	27260156	G402	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.01926884198207901	[51]	[104,62,60,28]	0	hSpCas9	negative selection	6902013
166510331	166510354	6	-	27260156	G402	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.6073855520722639	[169]	[523,383,308,90]	7	hSpCas9	negative selection	6902014
166531263	166531286	6	+	27260156	G402	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.7331591920526672	[113]	[40,94,68,121]	-7	hSpCas9	negative selection	6902015
166538766	166538789	6	-	27260156	G402	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-1.197852211406734	[186]	[49,76,182,79]	-8	hSpCas9	negative selection	6966266
166510328	166510351	6	+	27260156	G402	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.4624442357315044	[1414]	[2150,2535,2882,1934]	6	hSpCas9	negative selection	6966267
166538739	166538762	6	-	27260156	G402	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.41982731950773755	[443]	[358,779,311,192]	-5	hSpCas9	negative selection	6966268
166531276	166531299	6	-	27260156	L33	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.38418058870231553	[51]	[43,31,48,71]	7	hSpCas9	negative selection	7023264
166510331	166510354	6	-	27260156	L33	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.32654137364417957	[169]	[132,118,126,228]	7	hSpCas9	negative selection	7023265
166531263	166531286	6	+	27260156	L33	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.4604598525552026	[113]	[107,27,70,41]	-8	hSpCas9	negative selection	7023266
166538766	166538789	6	-	27260156	L33	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.27158736872059164	[186]	[177,59,95,141]	-6	hSpCas9	negative selection	7087517
166510328	166510351	6	+	27260156	L33	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.16042780532480205	[1414]	[1571,671,843,1767]	3	hSpCas9	negative selection	7087518
166538739	166538762	6	-	27260156	L33	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.2605222952919428	[443]	[361,155,266,315]	-6	hSpCas9	negative selection	7087519
166531276	166531299	6	-	27260156	K562	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.8670515147202478	[51]	[18,0,244,63]	9	hSpCas9	negative selection	7144515
166510331	166510354	6	-	27260156	K562	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.13515185036075272	[169]	[98,308,117,140]	1	hSpCas9	negative selection	7144516
166531263	166531286	6	+	27260156	K562	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-1.8797178362823828	[113]	[27,3,42,32]	-9	hSpCas9	negative selection	7144517
166538766	166538789	6	-	27260156	K562	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.1356059212566425	[186]	[338,217,77,115]	1	hSpCas9	negative selection	7208768
166510328	166510351	6	+	27260156	K562	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.48594875847779506	[1414]	[1232,1844,2514,1433]	6	hSpCas9	negative selection	7208769
166538739	166538762	6	-	27260156	K562	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.10175492118709434	[443]	[322,479,407,269]	-1	hSpCas9	negative selection	7208770
166531276	166531299	6	-	27260156	HT29	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-1.1812112196154123	[51]	[31,14,48,15]	-9	hSpCas9	negative selection	7265766
166510331	166510354	6	-	27260156	HT29	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.2878472980761251	[169]	[261,362,242,160]	5	hSpCas9	negative selection	7265767
166531263	166531286	6	+	27260156	HT29	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	0.1934371391123635	[113]	[140,160,156,170]	4	hSpCas9	negative selection	7265768
166538766	166538789	6	-	27260156	HT29	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.08285934742305057	[186]	[229,224,233,174]	-2	hSpCas9	negative selection	7330019
166510328	166510351	6	+	27260156	HT29	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.4494724058937061	[1414]	[2737,2348,1970,2349]	8	hSpCas9	negative selection	7330020
166538739	166538762	6	-	27260156	HT29	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.1622921579764043	[443]	[434,446,661,386]	-3	hSpCas9	negative selection	7330021
166531276	166531299	6	-	27260156	MHHES1	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.3240805684471404	[51]	[55,159,59,31]	6	hSpCas9	negative selection	7387017
166510331	166510354	6	-	27260156	MHHES1	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.29865205462363664	[169]	[335,228,240,159]	5	hSpCas9	negative selection	7387018
166531263	166531286	6	+	27260156	MHHES1	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	0.23363601896543962	[113]	[341,68,120,95]	4	hSpCas9	negative selection	7387019
166538766	166538789	6	-	27260156	MHHES1	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.03313305943003764	[186]	[158,334,228,153]	0	hSpCas9	negative selection	7451270
166510328	166510351	6	+	27260156	MHHES1	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.3127452746137298	[1414]	[2450,2135,1776,1655]	5	hSpCas9	negative selection	7451271
166538739	166538762	6	-	27260156	MHHES1	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.12389208374892025	[443]	[558,511,445,350]	-2	hSpCas9	negative selection	7451272
166531276	166531299	6	-	27260156	MEWO	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.04961637910180006	[51]	[97,22,29]	-1	hSpCas9	negative selection	7508268
166510331	166510354	6	-	27260156	MEWO	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.03792829946228249	[169]	[186,141,141]	-1	hSpCas9	negative selection	7508269
166531263	166531286	6	+	27260156	MEWO	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.44912919513452954	[113]	[70,71,89]	-7	hSpCas9	negative selection	7508270
166538766	166538789	6	-	27260156	MEWO	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.08235724172688896	[186]	[239,200,68]	-2	hSpCas9	negative selection	7572521
166510328	166510351	6	+	27260156	MEWO	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.3638758756106599	[1414]	[1996,1549,1620]	7	hSpCas9	negative selection	7572522
166538739	166538762	6	-	27260156	MEWO	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.2757052645483603	[443]	[366,330,335]	-6	hSpCas9	negative selection	7572523
166531276	166531299	6	-	27260156	LNCAPCLONEFGC	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.3667294810175106	[51]	[97,24,83,40]	6	hSpCas9	negative selection	7629519
166510331	166510354	6	-	27260156	LNCAPCLONEFGC	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.1828584258402013	[169]	[159,121,242,187]	3	hSpCas9	negative selection	7629520
166531263	166531286	6	+	27260156	LNCAPCLONEFGC	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.10466107881782527	[113]	[142,72,97,70]	-2	hSpCas9	negative selection	7629521
166538766	166538789	6	-	27260156	LNCAPCLONEFGC	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.29763000728585354	[186]	[237,211,161,212]	5	hSpCas9	negative selection	7693772
166510328	166510351	6	+	27260156	LNCAPCLONEFGC	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.4403293090470657	[1414]	[1371,1881,2024,1716]	7	hSpCas9	negative selection	7693773
166538739	166538762	6	-	27260156	LNCAPCLONEFGC	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.43300590511535164	[443]	[203,316,290,378]	-6	hSpCas9	negative selection	7693774
166531276	166531299	6	-	27260156	PANC0327	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.3429407576207666	[51]	[110,70,29,24]	5	hSpCas9	negative selection	7750770
166510331	166510354	6	-	27260156	PANC0327	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	1.3584612868035235	[169]	[443,351,409,351]	9	hSpCas9	negative selection	7750771
166531263	166531286	6	+	27260156	PANC0327	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-1.425763484504723	[113]	[66,30,18,36]	-9	hSpCas9	negative selection	7750772
166538766	166538789	6	-	27260156	PANC0327	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.05324982501991271	[186]	[135,79,321,110]	-1	hSpCas9	negative selection	7815023
166510328	166510351	6	+	27260156	PANC0327	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.5105112451654674	[1414]	[2360,1906,1768,1156]	7	hSpCas9	negative selection	7815024
166538739	166538762	6	-	27260156	PANC0327	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.7109651609874986	[443]	[268,202,278,219]	-7	hSpCas9	negative selection	7815025
166531276	166531299	6	-	27260156	NCIH2009	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.8814262786729867	[51]	[215,107,93]	9	hSpCas9	negative selection	7872021
166510331	166510354	6	-	27260156	NCIH2009	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.4866336268630831	[169]	[311,427,251]	6	hSpCas9	negative selection	7872022
166531263	166531286	6	+	27260156	NCIH2009	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.5691063176944802	[113]	[94,131,91]	-6	hSpCas9	negative selection	7872023
166538766	166538789	6	-	27260156	NCIH2009	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.11085315389848316	[186]	[209,247,260]	-1	hSpCas9	negative selection	7936274
166510328	166510351	6	+	27260156	NCIH2009	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.24606703429835575	[1414]	[2484,2160,2414]	3	hSpCas9	negative selection	7936275
166538739	166538762	6	-	27260156	NCIH2009	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.11488212325402253	[443]	[772,360,626]	-2	hSpCas9	negative selection	7936276
166531276	166531299	6	-	27260156	NCIH1373	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	1.2400082253313012	[51]	[18,250,80,44]	9	hSpCas9	negative selection	7993272
166510331	166510354	6	-	27260156	NCIH1373	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.1735331204155961	[169]	[280,222,200,41]	1	hSpCas9	negative selection	7993273
166531263	166531286	6	+	27260156	NCIH1373	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-1.7096011305312322	[113]	[46,59,41,0]	-9	hSpCas9	negative selection	7993274
166538766	166538789	6	-	27260156	NCIH1373	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.23321088880954166	[186]	[524,284,83,32]	2	hSpCas9	negative selection	8057525
166510328	166510351	6	+	27260156	NCIH1373	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.6967382736196275	[1414]	[3550,2048,2451,635]	7	hSpCas9	negative selection	8057526
166538739	166538762	6	-	27260156	NCIH1373	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.42402848588002184	[443]	[367,323,381,108]	-4	hSpCas9	negative selection	8057527
166531276	166531299	6	-	27260156	PATU8902	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.4442257572930597	[51]	[244,48,62,35]	4	hSpCas9	negative selection	8114523
166510331	166510354	6	-	27260156	PATU8902	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.010676381393390555	[169]	[118,603,131,95]	0	hSpCas9	negative selection	8114524
166531263	166531286	6	+	27260156	PATU8902	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-1.0849723903799129	[113]	[62,124,41,77]	-7	hSpCas9	negative selection	8114525
166538766	166538789	6	-	27260156	PATU8902	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.5411379786232966	[186]	[208,708,293,318]	5	hSpCas9	negative selection	8178776
166510328	166510351	6	+	27260156	PATU8902	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.451159234633957	[1414]	[2305,2307,2463,3882]	5	hSpCas9	negative selection	8178777
166538739	166538762	6	-	27260156	PATU8902	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	0.05465256780269232	[443]	[549,358,851,762]	0	hSpCas9	negative selection	8178778
166531276	166531299	6	-	27260156	PANC1	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.8601353336902706	[51]	[17,56,13,16]	-8	hSpCas9	negative selection	8235774
166510331	166510354	6	-	27260156	PANC1	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.43559517810764214	[169]	[213,334,103,165]	7	hSpCas9	negative selection	8235775
166531263	166531286	6	+	27260156	PANC1	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.46912583661421703	[113]	[62,94,32,91]	-6	hSpCas9	negative selection	8235776
166538766	166538789	6	-	27260156	PANC1	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.39314529742845017	[186]	[83,150,96,155]	-6	hSpCas9	negative selection	8300027
166510328	166510351	6	+	27260156	PANC1	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.34399930098572296	[1414]	[1348,1910,1695,1308]	5	hSpCas9	negative selection	8300028
166538739	166538762	6	-	27260156	PANC1	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.6704375608539227	[443]	[213,228,289,222]	-7	hSpCas9	negative selection	8300029
166531276	166531299	6	-	27260156	PANC0813	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.22488861804801763	[51]	[84,71,23,31]	-4	hSpCas9	negative selection	8357025
166510331	166510354	6	-	27260156	PANC0813	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.5861720264381438	[169]	[188,142,110,95]	-7	hSpCas9	negative selection	8357026
166531263	166531286	6	+	27260156	PANC0813	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-1.1433126946139378	[113]	[85,34,49,72]	-9	hSpCas9	negative selection	8357027
166538766	166538789	6	-	27260156	PANC0813	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.012291224961607838	[186]	[312,245,186,151]	0	hSpCas9	negative selection	8421278
166510328	166510351	6	+	27260156	PANC0813	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.16929399455496785	[1414]	[2093,2073,1663,1671]	2	hSpCas9	negative selection	8421279
166538739	166538762	6	-	27260156	PANC0813	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.29159104570280087	[443]	[565,394,308,444]	-4	hSpCas9	negative selection	8421280
166531276	166531299	6	-	27260156	RDES	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.39156140673130535	[51]	[27,44,43,71]	-6	hSpCas9	negative selection	8478276
166510331	166510354	6	-	27260156	RDES	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.4786550912375346	[169]	[222,312,264,288]	7	hSpCas9	negative selection	8478277
166531263	166531286	6	+	27260156	RDES	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.3329933541967991	[113]	[102,103,107,96]	-5	hSpCas9	negative selection	8478278
166538766	166538789	6	-	27260156	RDES	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.10676348261484869	[186]	[108,227,242,392]	1	hSpCas9	negative selection	8542529
166510328	166510351	6	+	27260156	RDES	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.4123167858924839	[1414]	[1798,2296,2104,2509]	6	hSpCas9	negative selection	8542530
166538739	166538762	6	-	27260156	RDES	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.3607347508232201	[443]	[314,386,511,385]	-6	hSpCas9	negative selection	8542531
166531276	166531299	6	-	27260156	PC3	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.42119404330557186	[51]	[12,29,75,60]	-7	hSpCas9	negative selection	8599527
166510331	166510354	6	-	27260156	PC3	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.48270504971476547	[169]	[183,223,284,269]	8	hSpCas9	negative selection	8599528
166531263	166531286	6	+	27260156	PC3	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.337411657195807	[113]	[39,160,92,76]	-6	hSpCas9	negative selection	8599529
166538766	166538789	6	-	27260156	PC3	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.15115760707625792	[186]	[175,139,415,166]	3	hSpCas9	negative selection	8663780
166510328	166510351	6	+	27260156	PC3	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.2481020381808845	[1414]	[1102,1612,2654,1799]	5	hSpCas9	negative selection	8663781
166538739	166538762	6	-	27260156	PC3	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.03971936183290019	[443]	[276,438,600,497]	-1	hSpCas9	negative selection	8663782
166531276	166531299	6	-	27260156	PATU8988T	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.9408621337816081	[51]	[107,133,11,139]	9	hSpCas9	negative selection	8720778
166510331	166510354	6	-	27260156	PATU8988T	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.5274285507957526	[169]	[272,175,314,170]	8	hSpCas9	negative selection	8720779
166531263	166531286	6	+	27260156	PATU8988T	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	0.03065522969857648	[113]	[70,97,126,155]	0	hSpCas9	negative selection	8720780
166538766	166538789	6	-	27260156	PATU8988T	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.6262172072494043	[186]	[122,78,69,199]	-7	hSpCas9	negative selection	8785031
166510328	166510351	6	+	27260156	PATU8988T	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.4092517284271511	[1414]	[1806,1796,1759,1904]	7	hSpCas9	negative selection	8785032
166538739	166538762	6	-	27260156	PATU8988T	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	0.24753979269196164	[443]	[691,332,477,518]	4	hSpCas9	negative selection	8785033
166531276	166531299	6	-	27260156	T47D	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.035716215600718915	[51]	[53,47,76,57]	-1	hSpCas9	negative selection	8842029
166510331	166510354	6	-	27260156	T47D	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.20207910579137267	[169]	[226,183,260,242]	4	hSpCas9	negative selection	8842030
166531263	166531286	6	+	27260156	T47D	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.4188718816060111	[113]	[121,65,94,117]	-7	hSpCas9	negative selection	8842031
166538766	166538789	6	-	27260156	T47D	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.09878842368847329	[186]	[201,191,225,193]	-2	hSpCas9	negative selection	8906282
166510328	166510351	6	+	27260156	T47D	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.32753290240520494	[1414]	[2000,2042,1960,2278]	7	hSpCas9	negative selection	8906283
166538739	166538762	6	-	27260156	T47D	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.1147388572201109	[443]	[526,399,473,517]	-3	hSpCas9	negative selection	8906284
166531276	166531299	6	-	27260156	SU8686	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.08629749661233665	[51]	[75,42,32,66]	1	hSpCas9	negative selection	8963280
166510331	166510354	6	-	27260156	SU8686	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.009337363129412246	[169]	[137,183,128,237]	0	hSpCas9	negative selection	8963281
166531263	166531286	6	+	27260156	SU8686	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.16400658131582135	[113]	[62,145,102,86]	-3	hSpCas9	negative selection	8963282
166538766	166538789	6	-	27260156	SU8686	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.024440913184371915	[186]	[225,185,188,139]	0	hSpCas9	negative selection	9027533
166510328	166510351	6	+	27260156	SU8686	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.13009171913308704	[1414]	[1303,1417,1651,1851]	2	hSpCas9	negative selection	9027534
166538739	166538762	6	-	27260156	SU8686	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.3920144944987713	[443]	[281,420,313,312]	-6	hSpCas9	negative selection	9027535
166531276	166531299	6	-	27260156	SKES1	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.6620463658999678	[51]	[28,21,15,58]	-8	hSpCas9	negative selection	9084531
166510331	166510354	6	-	27260156	SKES1	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.2950802078554644	[169]	[274,206,253,113]	6	hSpCas9	negative selection	9084532
166531263	166531286	6	+	27260156	SKES1	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.1740614993595413	[113]	[82,120,64,129]	-4	hSpCas9	negative selection	9084533
166538766	166538789	6	-	27260156	SKES1	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.01433431997374024	[186]	[138,175,230,182]	0	hSpCas9	negative selection	9148784
166510328	166510351	6	+	27260156	SKES1	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.23767124396837702	[1414]	[1661,1983,1469,1574]	5	hSpCas9	negative selection	9148785
166538739	166538762	6	-	27260156	SKES1	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.40551811549327726	[443]	[293,397,316,327]	-7	hSpCas9	negative selection	9148786
166531276	166531299	6	-	27260156	TOV112D	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.17880207262648007	[51]	[75,37,41,28]	-3	hSpCas9	negative selection	9205782
166510331	166510354	6	-	27260156	TOV112D	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.30533620665375216	[169]	[172,295,137,250]	6	hSpCas9	negative selection	9205783
166531263	166531286	6	+	27260156	TOV112D	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.30713422951291625	[113]	[86,36,104,124]	-6	hSpCas9	negative selection	9205784
166538766	166538789	6	-	27260156	TOV112D	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.2237449025179754	[186]	[108,149,200,173]	-4	hSpCas9	negative selection	9270035
166510328	166510351	6	+	27260156	TOV112D	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.17048171634573572	[1414]	[1577,2074,1720,1132]	3	hSpCas9	negative selection	9270036
166538739	166538762	6	-	27260156	TOV112D	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.10228903358483357	[443]	[407,462,353,441]	-2	hSpCas9	negative selection	9270037
166531276	166531299	6	-	27260156	TC71	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	0.31565368545704464	[51]	[56,69,54,97]	7	hSpCas9	negative selection	9327033
166510331	166510354	6	-	27260156	TC71	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.022312126437624924	[169]	[175,176,200,185]	0	hSpCas9	negative selection	9327034
166531263	166531286	6	+	27260156	TC71	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.18168228921754448	[113]	[94,154,57,125]	-5	hSpCas9	negative selection	9327035
166538766	166538789	6	-	27260156	TC71	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.1167800181774743	[186]	[181,245,151,158]	-3	hSpCas9	negative selection	9391286
166510328	166510351	6	+	27260156	TC71	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.214467800348755	[1414]	[1799,1622,1628,2005]	5	hSpCas9	negative selection	9391287
166538739	166538762	6	-	27260156	TC71	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.3606745828440931	[443]	[416,281,462,312]	-7	hSpCas9	negative selection	9391288
166531276	166531299	6	-	27260156	TC32	viability	AAGGTGAAGGGGTCCGACGCTGG	RPS6KA2	ENSG00000071242	-0.5262874798395529	[51]	[24,0,71,57]	-7	hSpCas9	negative selection	9448284
166510331	166510354	6	-	27260156	TC32	viability	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.23962160101260022	[169]	[120,152,295,215]	4	hSpCas9	negative selection	9448285
166531263	166531286	6	+	27260156	TC32	viability	GGCGTAGAGCTGCCCAGCGTCGG	RPS6KA2	ENSG00000071242	-0.5966428722596251	[113]	[58,49,54,124]	-8	hSpCas9	negative selection	9448286
166538766	166538789	6	-	27260156	TC32	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.1630141609856839	[186]	[141,114,218,171]	-3	hSpCas9	negative selection	9512537
166510328	166510351	6	+	27260156	TC32	viability	TCTCCATCTTCGATCTCACTCGG	RPS6KA2	ENSG00000071242	0.2637448853585118	[1414]	[1535,1340,1832,1728]	5	hSpCas9	negative selection	9512538
166538739	166538762	6	-	27260156	TC32	viability	AGACATCAGCCATCATGTGAAGG	RPS6KA2	ENSG00000071242	-0.22834910523465918	[443]	[291,364,464,299]	-4	hSpCas9	negative selection	9512539
166498529	166498552	6	-	27869803	HPAFII	viability after 27 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	0.7551585144225403	[45]	[36,43,NaN]	6	hSpCas9	negative selection	9594381
166504594	166504617	6	-	27869803	HPAFII	viability after 27 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-0.8077381721674507	[450]	[159,114,NaN]	-5	hSpCas9	negative selection	9594382
166508267	166508290	6	-	27869803	HPAFII	viability after 27 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.38244668532179094	[530]	[574,187,NaN]	3	hSpCas9	negative selection	9594383
166510331	166510354	6	-	27869803	HPAFII	viability after 27 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.4149334124824429	[230]	[77,101,NaN]	-3	hSpCas9	negative selection	9594384
166538724	166538747	6	-	27869803	HPAFII	viability after 27 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.48341559239171683	[328]	[273,214,NaN]	4	hSpCas9	negative selection	9594385
166626918	166626941	6	+	27869803	HPAFII	viability after 27 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	1.1244287409612155	[73]	[128,47,NaN]	8	hSpCas9	negative selection	9594386
166498529	166498552	6	-	27869803	HPAFII	viability after 15 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	-0.43436354995193804	[45]	[51,26,NaN]	-5	hSpCas9	negative selection	9676830
166504594	166504617	6	-	27869803	HPAFII	viability after 15 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-0.48676438919122433	[450]	[475,264,NaN]	-5	hSpCas9	negative selection	9676831
166508267	166508290	6	-	27869803	HPAFII	viability after 15 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.5926045667563582	[530]	[1232,628,NaN]	6	hSpCas9	negative selection	9676832
166510331	166510354	6	-	27869803	HPAFII	viability after 15 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.17948212926155682	[230]	[262,191,NaN]	-2	hSpCas9	negative selection	9676833
166538724	166538747	6	-	27869803	HPAFII	viability after 15 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.3417099384907526	[328]	[637,329,NaN]	4	hSpCas9	negative selection	9676834
166626918	166626941	6	+	27869803	HPAFII	viability after 15 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	0.9281807945551784	[73]	[175,135,NaN]	8	hSpCas9	negative selection	9676835
166498529	166498552	6	-	27869803	ASPC1	viability after 36 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	-0.4842789344511753	[120]	[8,78,5]	-5	hSpCas9	negative selection	9759279
166504594	166504617	6	-	27869803	ASPC1	viability after 36 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-0.1029615253578165	[857]	[374,179,286]	-1	hSpCas9	negative selection	9759280
166508267	166508290	6	-	27869803	ASPC1	viability after 36 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.3103877403991211	[2122]	[911,1116,756]	3	hSpCas9	negative selection	9759281
166510331	166510354	6	-	27869803	ASPC1	viability after 36 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.42770524785423875	[567]	[134,324,309]	4	hSpCas9	negative selection	9759282
166538724	166538747	6	-	27869803	ASPC1	viability after 36 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.8580053796594624	[586]	[140,688,276]	8	hSpCas9	negative selection	9759283
166626918	166626941	6	+	27869803	ASPC1	viability after 36 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	-0.44281109546974107	[267]	[3,61,118]	-4	hSpCas9	negative selection	9759284
166498529	166498552	6	-	27869803	PATU8988S	viability after 35 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	-0.3116056883424001	[116]	[23,51,NaN]	-3	hSpCas9	negative selection	9841728
166504594	166504617	6	-	27869803	PATU8988S	viability after 35 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	0.22745260403778078	[947]	[449,443,NaN]	2	hSpCas9	negative selection	9841729
166508267	166508290	6	-	27869803	PATU8988S	viability after 35 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.3510659142918202	[1425]	[753,710,NaN]	4	hSpCas9	negative selection	9841730
166510331	166510354	6	-	27869803	PATU8988S	viability after 35 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.708251505668064	[397]	[214,308,NaN]	7	hSpCas9	negative selection	9841731
166538724	166538747	6	-	27869803	PATU8988S	viability after 35 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	-0.07450315652113826	[731]	[268,290,NaN]	-1	hSpCas9	negative selection	9841732
166626918	166626941	6	+	27869803	PATU8988S	viability after 35 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	-0.3625289786256647	[216]	[57,77,NaN]	-4	hSpCas9	negative selection	9841733
166498529	166498552	6	-	27869803	PATU8988S	viability after 31 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	0.5721929496744687	[116]	[82,51,NaN]	6	hSpCas9	negative selection	9924177
166504594	166504617	6	-	27869803	PATU8988S	viability after 31 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	0.5785797917036929	[947]	[516,624,NaN]	7	hSpCas9	negative selection	9924178
166508267	166508290	6	-	27869803	PATU8988S	viability after 31 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.24562431178354727	[1425]	[601,765,NaN]	3	hSpCas9	negative selection	9924179
166510331	166510354	6	-	27869803	PATU8988S	viability after 31 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.7934515372704075	[397]	[183,390,NaN]	8	hSpCas9	negative selection	9924180
166538724	166538747	6	-	27869803	PATU8988S	viability after 31 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.2368609188983078	[731]	[339,348,NaN]	3	hSpCas9	negative selection	9924181
166626918	166626941	6	+	27869803	PATU8988S	viability after 31 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	-0.8671236554176922	[216]	[35,61,NaN]	-7	hSpCas9	negative selection	9924182
166498529	166498552	6	-	27869803	HPAFII	viability after 35 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	1.4171308905114475	[45]	[88,31,NaN]	8	hSpCas9	negative selection	10006626
166504594	166504617	6	-	27869803	HPAFII	viability after 35 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-0.6029624570105812	[450]	[91,215,NaN]	-4	hSpCas9	negative selection	10006627
166508267	166508290	6	-	27869803	HPAFII	viability after 35 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.6220567545234137	[530]	[575,230,NaN]	4	hSpCas9	negative selection	10006628
166510331	166510354	6	-	27869803	HPAFII	viability after 35 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	0.34364068191457053	[230]	[114,185,NaN]	2	hSpCas9	negative selection	10006629
166538724	166538747	6	-	27869803	HPAFII	viability after 35 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.5558048408829894	[328]	[265,220,NaN]	3	hSpCas9	negative selection	10006630
166626918	166626941	6	+	27869803	HPAFII	viability after 35 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	1.7332553142874585	[73]	[172,69,NaN]	9	hSpCas9	negative selection	10006631
166498529	166498552	6	-	27869803	HPAFII	viability after 31 days	GACACACGCAGAGTGCCGACTGG	RPS6KA2	ENSG00000071242	1.2553366878337324	[45]	[97,21,NaN]	8	hSpCas9	negative selection	10089075
166504594	166504617	6	-	27869803	HPAFII	viability after 31 days	CTAGGTCATGTTCACGGAGGAGG	RPS6KA2	ENSG00000071242	-0.7318257146809031	[450]	[127,178,NaN]	-5	hSpCas9	negative selection	10089076
166508267	166508290	6	-	27869803	HPAFII	viability after 31 days	CCCACAGCCTTTCAGACGGAAGG	RPS6KA2	ENSG00000071242	0.4215645322229633	[530]	[513,273,NaN]	3	hSpCas9	negative selection	10089077
166510331	166510354	6	-	27869803	HPAFII	viability after 31 days	GGACCGAGTGAGATCGAAGATGG	RPS6KA2	ENSG00000071242	-0.2494373874702081	[230]	[87,131,NaN]	-2	hSpCas9	negative selection	10089078
166538724	166538747	6	-	27869803	HPAFII	viability after 31 days	TGTGAAGGAGGGCTTTGAGAAGG	RPS6KA2	ENSG00000071242	0.73248132941147	[328]	[312,299,NaN]	5	hSpCas9	negative selection	10089079
166626918	166626941	6	+	27869803	HPAFII	viability after 31 days	TACCTCGAGCCGGCTCAGGCTGG	RPS6KA2	ENSG00000071242	0.8483330261493764	[73]	[91,55,NaN]	6	hSpCas9	negative selection	10089080
166504544	166504567	6	+	28162770	P31FUJ	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	1.0082058950894162	[87]	[207]	9	hSpCas9	negative selection	10228081
166538766	166538789	6	-	28162770	P31FUJ	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	1.0626536791117926	[54]	[134]	9	hSpCas9	negative selection	10228082
166490684	166490707	6	-	28162770	P31FUJ	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-4.096300204509516	[261]	[17]	-9	hSpCas9	negative selection	10228083
166488884	166488907	6	-	28162770	P31FUJ	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	-0.07807960961573657	[105]	[117]	-1	hSpCas9	negative selection	10228084
166469849	166469872	6	+	28162770	P31FUJ	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	0.7870973530233261	[107]	[218]	8	hSpCas9	negative selection	10228085
166459506	166459529	6	-	28162770	P31FUJ	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	0.20191766072616502	[90]	[122]	2	hSpCas9	negative selection	10228086
166448786	166448809	6	-	28162770	P31FUJ	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	0.09871193930218164	[239]	[301]	1	hSpCas9	negative selection	10228087
166430559	166430582	6	-	28162770	P31FUJ	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	1.1663987468137564	[228]	[603]	9	hSpCas9	negative selection	10228088
166419931	166419954	6	-	28162770	P31FUJ	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	0.08328501188392323	[395]	[492]	0	hSpCas9	negative selection	10228089
166413856	166413879	6	-	28162770	P31FUJ	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	0.40197618992450845	[388]	[603]	4	hSpCas9	negative selection	10228090
166504544	166504567	6	+	28162770	TF1	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	NaN	[NaN]	[110]	1	hSpCas9	negative selection	10397447
166538766	166538789	6	-	28162770	TF1	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10397448
166490684	166490707	6	-	28162770	TF1	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10397449
166488884	166488907	6	-	28162770	TF1	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10397450
166469849	166469872	6	+	28162770	TF1	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	NaN	[NaN]	[52]	1	hSpCas9	negative selection	10397451
166459506	166459529	6	-	28162770	TF1	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	NaN	[NaN]	[141]	1	hSpCas9	negative selection	10397452
166448786	166448809	6	-	28162770	TF1	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	NaN	[NaN]	[184]	1	hSpCas9	negative selection	10397453
166430559	166430582	6	-	28162770	TF1	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	NaN	[NaN]	[163]	1	hSpCas9	negative selection	10397454
166419931	166419954	6	-	28162770	TF1	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	NaN	[NaN]	[220]	1	hSpCas9	negative selection	10397455
166413856	166413879	6	-	28162770	TF1	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	NaN	[NaN]	[205]	1	hSpCas9	negative selection	10397456
166504544	166504567	6	+	28162770	SKM1	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	-0.11150831521699056	[32]	[53]	-1	hSpCas9	negative selection	10566813
166538766	166538789	6	-	28162770	SKM1	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-1.0564669516590286	[19]	[16]	-6	hSpCas9	negative selection	10566814
166490684	166490707	6	-	28162770	SKM1	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-2.80472370659017	[82]	[20]	-9	hSpCas9	negative selection	10566815
166488884	166488907	6	-	28162770	SKM1	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	0.9293191891212705	[29]	[100]	8	hSpCas9	negative selection	10566816
166469849	166469872	6	+	28162770	SKM1	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	-0.014646775964401448	[35]	[62]	0	hSpCas9	negative selection	10566817
166459506	166459529	6	-	28162770	SKM1	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	0.5219527031953557	[25]	[65]	5	hSpCas9	negative selection	10566818
166448786	166448809	6	-	28162770	SKM1	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	0.3193541512235361	[33]	[74]	3	hSpCas9	negative selection	10566819
166430559	166430582	6	-	28162770	SKM1	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	0.24511249783653138	[62]	[131]	2	hSpCas9	negative selection	10566820
166419931	166419954	6	-	28162770	SKM1	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	-0.30004899482664976	[77]	[111]	-3	hSpCas9	negative selection	10566821
166413856	166413879	6	-	28162770	SKM1	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	0.49992639686535684	[65]	[164]	5	hSpCas9	negative selection	10566822
166504544	166504567	6	+	28162770	SKM1	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	-0.11150831521699056	[32]	[53]	-1	hSpCas9	negative selection	10736179
166538766	166538789	6	-	28162770	SKM1	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-1.0564669516590286	[19]	[16]	-6	hSpCas9	negative selection	10736180
166490684	166490707	6	-	28162770	SKM1	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-2.80472370659017	[82]	[20]	-9	hSpCas9	negative selection	10736181
166488884	166488907	6	-	28162770	SKM1	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	0.9293191891212705	[29]	[100]	8	hSpCas9	negative selection	10736182
166469849	166469872	6	+	28162770	SKM1	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	-0.014646775964401448	[35]	[62]	0	hSpCas9	negative selection	10736183
166459506	166459529	6	-	28162770	SKM1	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	0.5219527031953557	[25]	[65]	5	hSpCas9	negative selection	10736184
166448786	166448809	6	-	28162770	SKM1	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	0.3193541512235361	[33]	[74]	3	hSpCas9	negative selection	10736185
166430559	166430582	6	-	28162770	SKM1	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	0.24511249783653138	[62]	[131]	2	hSpCas9	negative selection	10736186
166419931	166419954	6	-	28162770	SKM1	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	-0.30004899482664976	[77]	[111]	-3	hSpCas9	negative selection	10736187
166413856	166413879	6	-	28162770	SKM1	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	0.49992639686535684	[65]	[164]	5	hSpCas9	negative selection	10736188
166504544	166504567	6	+	28162770	PL21	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	-0.0761916139579315	[108]	[44]	0	hSpCas9	negative selection	10905545
166538766	166538789	6	-	28162770	PL21	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.03252114230095504	[46]	[19]	0	hSpCas9	negative selection	10905546
166490684	166490707	6	-	28162770	PL21	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-2.2829432722126226	[245]	[21]	-8	hSpCas9	negative selection	10905547
166488884	166488907	6	-	28162770	PL21	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	-0.46077173946513483	[116]	[36]	-3	hSpCas9	negative selection	10905548
166469849	166469872	6	+	28162770	PL21	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	-1.540101111709747	[146]	[21]	-7	hSpCas9	negative selection	10905549
166459506	166459529	6	-	28162770	PL21	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	-1.0728788799170959	[86]	[17]	-6	hSpCas9	negative selection	10905550
166448786	166448809	6	-	28162770	PL21	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	0.7124743151230789	[128]	[91]	6	hSpCas9	negative selection	10905551
166430559	166430582	6	-	28162770	PL21	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	0.42895830498520104	[127]	[74]	4	hSpCas9	negative selection	10905552
166419931	166419954	6	-	28162770	PL21	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	-0.7473929656165443	[296]	[76]	-5	hSpCas9	negative selection	10905553
166413856	166413879	6	-	28162770	PL21	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	0.5117993739228552	[281]	[174]	4	hSpCas9	negative selection	10905554
166504544	166504567	6	+	28162770	P31FUJ	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	1.0082058950894162	[87]	[207]	9	hSpCas9	negative selection	11074911
166538766	166538789	6	-	28162770	P31FUJ	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	1.0626536791117926	[54]	[134]	9	hSpCas9	negative selection	11074912
166490684	166490707	6	-	28162770	P31FUJ	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-4.096300204509516	[261]	[17]	-9	hSpCas9	negative selection	11074913
166488884	166488907	6	-	28162770	P31FUJ	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	-0.07807960961573657	[105]	[117]	-1	hSpCas9	negative selection	11074914
166469849	166469872	6	+	28162770	P31FUJ	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	0.7870973530233261	[107]	[218]	8	hSpCas9	negative selection	11074915
166459506	166459529	6	-	28162770	P31FUJ	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	0.20191766072616502	[90]	[122]	2	hSpCas9	negative selection	11074916
166448786	166448809	6	-	28162770	P31FUJ	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	0.09871193930218164	[239]	[301]	1	hSpCas9	negative selection	11074917
166430559	166430582	6	-	28162770	P31FUJ	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	1.1663987468137564	[228]	[603]	9	hSpCas9	negative selection	11074918
166419931	166419954	6	-	28162770	P31FUJ	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	0.08328501188392323	[395]	[492]	0	hSpCas9	negative selection	11074919
166413856	166413879	6	-	28162770	P31FUJ	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	0.40197618992450845	[388]	[603]	4	hSpCas9	negative selection	11074920
166504544	166504567	6	+	28162770	OCIAML5	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	-0.06855839076076053	[60]	[104]	0	hSpCas9	negative selection	11244277
166538766	166538789	6	-	28162770	OCIAML5	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-3.1960209720813575	[65]	[12]	-9	hSpCas9	negative selection	11244278
166490684	166490707	6	-	28162770	OCIAML5	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-2.6413875700913394	[158]	[45]	-8	hSpCas9	negative selection	11244279
166488884	166488907	6	-	28162770	OCIAML5	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	0.20342854172770664	[50]	[105]	1	hSpCas9	negative selection	11244280
166469849	166469872	6	+	28162770	OCIAML5	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	-0.01629596664230637	[78]	[140]	0	hSpCas9	negative selection	11244281
166459506	166459529	6	-	28162770	OCIAML5	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	0.13399423817812917	[51]	[102]	1	hSpCas9	negative selection	11244282
166448786	166448809	6	-	28162770	OCIAML5	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	0.5422123682480495	[104]	[275]	5	hSpCas9	negative selection	11244283
166430559	166430582	6	-	28162770	OCIAML5	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	0.43803607816796764	[109]	[268]	4	hSpCas9	negative selection	11244284
166419931	166419954	6	-	28162770	OCIAML5	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	-0.46379598114793874	[135]	[177]	-3	hSpCas9	negative selection	11244285
166413856	166413879	6	-	28162770	OCIAML5	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	0.18312285759830327	[242]	[497]	1	hSpCas9	negative selection	11244286
166504544	166504567	6	+	28162770	EOL1	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	-1.1022522877731808	[162]	[39]	-6	hSpCas9	negative selection	11413643
166538766	166538789	6	-	28162770	EOL1	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	1.2382082504742966	[69]	[86]	8	hSpCas9	negative selection	11413644
166490684	166490707	6	-	28162770	EOL1	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-1.4368314740355514	[518]	[100]	-7	hSpCas9	negative selection	11413645
166488884	166488907	6	-	28162770	EOL1	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	-0.5147372739549865	[159]	[58]	-4	hSpCas9	negative selection	11413646
166469849	166469872	6	+	28162770	EOL1	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	0.46309980733473277	[178]	[129]	4	hSpCas9	negative selection	11413647
166459506	166459529	6	-	28162770	EOL1	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	1.1649067394364314	[170]	[201]	8	hSpCas9	negative selection	11413648
166448786	166448809	6	-	28162770	EOL1	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	-0.634183187577442	[217]	[73]	-4	hSpCas9	negative selection	11413649
166430559	166430582	6	-	28162770	EOL1	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	0.6453241276374104	[232]	[191]	6	hSpCas9	negative selection	11413650
166419931	166419954	6	-	28162770	EOL1	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	0.14821974513355474	[321]	[187]	1	hSpCas9	negative selection	11413651
166413856	166413879	6	-	28162770	EOL1	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	0.07165206560274534	[353]	[195]	0	hSpCas9	negative selection	11413652
166504544	166504567	6	+	28162770	MOLM13	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	0.9039884963512522	[101]	[137]	7	hSpCas9	negative selection	11583009
166538766	166538789	6	-	28162770	MOLM13	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.8196872085520062	[82]	[33]	-4	hSpCas9	negative selection	11583010
166490684	166490707	6	-	28162770	MOLM13	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-4.191908352099167	[454]	[17]	-9	hSpCas9	negative selection	11583011
166488884	166488907	6	-	28162770	MOLM13	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	1.5783133712382296	[131]	[284]	9	hSpCas9	negative selection	11583012
166469849	166469872	6	+	28162770	MOLM13	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	-0.3433489750002531	[185]	[105]	-2	hSpCas9	negative selection	11583013
166459506	166459529	6	-	28162770	MOLM13	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	0.06735145196085002	[131]	[99]	0	hSpCas9	negative selection	11583014
166448786	166448809	6	-	28162770	MOLM13	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	0.6623277413100255	[200]	[229]	5	hSpCas9	negative selection	11583015
166430559	166430582	6	-	28162770	MOLM13	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	-1.2911025189516263	[307]	[90]	-6	hSpCas9	negative selection	11583016
166419931	166419954	6	-	28162770	MOLM13	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	-0.501608530058077	[467]	[238]	-3	hSpCas9	negative selection	11583017
166413856	166413879	6	-	28162770	MOLM13	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	-0.648877684008561	[372]	[171]	-4	hSpCas9	negative selection	11583018
166504544	166504567	6	+	28162770	HEL	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	0.12816565917059863	[129]	[90]	1	hSpCas9	negative selection	11752375
166538766	166538789	6	-	28162770	HEL	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.2503459640831309	[51]	[27]	-2	hSpCas9	negative selection	11752376
166490684	166490707	6	-	28162770	HEL	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-2.5578829666648715	[284]	[30]	-8	hSpCas9	negative selection	11752377
166488884	166488907	6	-	28162770	HEL	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	-1.2223315879135344	[152]	[41]	-6	hSpCas9	negative selection	11752378
166469849	166469872	6	+	28162770	HEL	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	-0.7861044668035173	[174]	[64]	-5	hSpCas9	negative selection	11752379
166459506	166459529	6	-	28162770	HEL	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	0.5432031584494423	[149]	[139]	4	hSpCas9	negative selection	11752380
166448786	166448809	6	-	28162770	HEL	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	-0.357261167999643	[165]	[82]	-3	hSpCas9	negative selection	11752381
166430559	166430582	6	-	28162770	HEL	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	0.31890114710436335	[188]	[150]	2	hSpCas9	negative selection	11752382
166419931	166419954	6	-	28162770	HEL	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	-0.7596618416005614	[340]	[128]	-5	hSpCas9	negative selection	11752383
166413856	166413879	6	-	28162770	HEL	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	0.3605956032188584	[303]	[249]	3	hSpCas9	negative selection	11752384
166504544	166504567	6	+	28162770	MV411	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	0.2670663575317078	[72]	[73]	2	hSpCas9	negative selection	11921741
166538766	166538789	6	-	28162770	MV411	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	-0.5509285880475745	[39]	[22]	-4	hSpCas9	negative selection	11921742
166490684	166490707	6	-	28162770	MV411	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-3.2276473321660073	[277]	[24]	-9	hSpCas9	negative selection	11921743
166488884	166488907	6	-	28162770	MV411	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	-0.9793333110642468	[109]	[46]	-6	hSpCas9	negative selection	11921744
166469849	166469872	6	+	28162770	MV411	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	1.9104025635052047	[71]	[227]	9	hSpCas9	negative selection	11921745
166459506	166459529	6	-	28162770	MV411	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	-1.069419554557165	[141]	[56]	-6	hSpCas9	negative selection	11921746
166448786	166448809	6	-	28162770	MV411	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	0.593613191916815	[117]	[149]	5	hSpCas9	negative selection	11921747
166430559	166430582	6	-	28162770	MV411	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	0.49089158764705315	[135]	[160]	4	hSpCas9	negative selection	11921748
166419931	166419954	6	-	28162770	MV411	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	-0.38932738017294866	[240]	[154]	-3	hSpCas9	negative selection	11921749
166413856	166413879	6	-	28162770	MV411	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	-0.20659408011193214	[299]	[218]	-1	hSpCas9	negative selection	11921750
166504544	166504567	6	+	28162770	MONOMAC1	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	-0.5840599701688011	[67]	[51]	-5	hSpCas9	negative selection	12091107
166538766	166538789	6	-	28162770	MONOMAC1	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.633038151498134	[17]	[31]	6	hSpCas9	negative selection	12091108
166490684	166490707	6	-	28162770	MONOMAC1	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-1.9217241114473231	[194]	[58]	-8	hSpCas9	negative selection	12091109
166488884	166488907	6	-	28162770	MONOMAC1	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	0.29171033840229943	[61]	[86]	3	hSpCas9	negative selection	12091110
166469849	166469872	6	+	28162770	MONOMAC1	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	0.8612617935051136	[96]	[201]	7	hSpCas9	negative selection	12091111
166459506	166459529	6	-	28162770	MONOMAC1	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	1.7671624315125993	[50]	[198]	9	hSpCas9	negative selection	12091112
166448786	166448809	6	-	28162770	MONOMAC1	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	-1.3237939893454924	[106]	[48]	-7	hSpCas9	negative selection	12091113
166430559	166430582	6	-	28162770	MONOMAC1	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	-0.02835501246787333	[128]	[144]	0	hSpCas9	negative selection	12091114
166419931	166419954	6	-	28162770	MONOMAC1	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	-0.1800637684558401	[168]	[170]	-1	hSpCas9	negative selection	12091115
166413856	166413879	6	-	28162770	MONOMAC1	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	-0.1385411977494092	[144]	[150]	-1	hSpCas9	negative selection	12091116
166504544	166504567	6	+	28162770	OCIAML2	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	0.02122327108751343	[23]	[134]	0	hSpCas9	negative selection	12260473
166538766	166538789	6	-	28162770	OCIAML2	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.2223924213364481	[14]	[96]	2	hSpCas9	negative selection	12260474
166490684	166490707	6	-	28162770	OCIAML2	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-2.438920965514823	[44]	[45]	-8	hSpCas9	negative selection	12260475
166488884	166488907	6	-	28162770	OCIAML2	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	1.5971147813936728	[12]	[217]	9	hSpCas9	negative selection	12260476
166469849	166469872	6	+	28162770	OCIAML2	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	-0.052486415095495786	[28]	[154]	0	hSpCas9	negative selection	12260477
166459506	166459529	6	-	28162770	OCIAML2	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	1.1659947953014875	[15]	[198]	9	hSpCas9	negative selection	12260478
166448786	166448809	6	-	28162770	OCIAML2	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	-1.4100882833071104	[34]	[72]	-7	hSpCas9	negative selection	12260479
166430559	166430582	6	-	28162770	OCIAML2	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	0.5591175181518908	[29]	[244]	5	hSpCas9	negative selection	12260480
166419931	166419954	6	-	28162770	OCIAML2	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	-0.913148060943112	[52]	[155]	-6	hSpCas9	negative selection	12260481
166413856	166413879	6	-	28162770	OCIAML2	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	-0.35773576883622776	[42]	[185]	-3	hSpCas9	negative selection	12260482
166504544	166504567	6	+	28162770	OCIAML3	viability	GTGGAGATGGTCTAAAGCCAAGG	RPS6KA2	ENSG00000071242	0.6690267655096308	[29]	[143]	6	hSpCas9	negative selection	12429839
166538766	166538789	6	-	28162770	OCIAML3	viability	GCAGGAAGAAGGCGTCGTGAAGG	RPS6KA2	ENSG00000071242	0.17651051355306957	[16]	[57]	1	hSpCas9	negative selection	12429840
166490684	166490707	6	-	28162770	OCIAML3	viability	GAAGGACAGGAAGGAGACCATGG	RPS6KA2	ENSG00000071242	-1.5261035758223598	[82]	[86]	-8	hSpCas9	negative selection	12429841
166488884	166488907	6	-	28162770	OCIAML3	viability	GCCGCAGTTCCTCAGTGGGGAGG	RPS6KA2	ENSG00000071242	0.07157332060527755	[28]	[91]	0	hSpCas9	negative selection	12429842
166469849	166469872	6	+	28162770	OCIAML3	viability	CTATGGTCACAAAGAAGGGATGG	RPS6KA2	ENSG00000071242	-0.022101292428453267	[36]	[109]	0	hSpCas9	negative selection	12429843
166459506	166459529	6	-	28162770	OCIAML3	viability	GCCACCGTTCAAACCAGCAGTGG	RPS6KA2	ENSG00000071242	0.7667397034537273	[21]	[112]	7	hSpCas9	negative selection	12429844
166448786	166448809	6	-	28162770	OCIAML3	viability	GATCAAGGAGGACATCGGGGTGG	RPS6KA2	ENSG00000071242	0.1657292615007011	[43]	[148]	1	hSpCas9	negative selection	12429845
166430559	166430582	6	-	28162770	OCIAML3	viability	GTAATGGAGCTGATGCGTGGTGG	RPS6KA2	ENSG00000071242	0.7279204545631993	[33]	[169]	6	hSpCas9	negative selection	12429846
166419931	166419954	6	-	28162770	OCIAML3	viability	GAAGCGTCAAGGCTATGATGCGG	RPS6KA2	ENSG00000071242	-0.06405924160748899	[97]	[282]	0	hSpCas9	negative selection	12429847
166413856	166413879	6	-	28162770	OCIAML3	viability	GCAAGTGCTCAAACACCCGTGGG	RPS6KA2	ENSG00000071242	-1.3946988321007565	[80]	[92]	-7	hSpCas9	negative selection	12429848