Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6217
• Symbol: RpS16
• Description: ribosomal protein S16

DataSource: http://genomecrispr.dkfz.de/#!/results/RpS16

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
39435690	39435713	19	-	26472758	Jiyoye	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-7.954768392229369	[328]	[0]	-9	hSpCas9	negative selection	139921
39435621	39435644	19	+	26472758	Jiyoye	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-3.5127713669280913	[332]	[21]	-9	hSpCas9	negative selection	139922
39433688	39433711	19	-	26472758	Jiyoye	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-1.5928246184941268	[7]	[1]	-8	hSpCas9	negative selection	139923
39435862	39435885	19	-	26472758	Jiyoye	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	0.200724504038447	[74]	[64]	1	hSpCas9	negative selection	139924
39435606	39435629	19	-	26472758	Jiyoye	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.439843758125247	[294]	[40]	-8	hSpCas9	negative selection	139925
39433654	39433677	19	+	26472758	Jiyoye	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	0.4202611405255334	[438]	[442]	3	hSpCas9	negative selection	139926
39433282	39433305	19	+	26472758	Jiyoye	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	1.4071753815058727	[0]	[1]	8	hSpCas9	negative selection	139927
39433338	39433361	19	+	26472758	Jiyoye	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-3.3043195251442143	[130]	[9]	-9	hSpCas9	negative selection	139928
39433323	39433346	19	+	26472758	Jiyoye	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.7101619127397757	[183]	[226]	5	hSpCas9	negative selection	139929
39435883	39435906	19	-	26472758	Jiyoye	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-2.0953249590233094	[67]	[11]	-8	hSpCas9	negative selection	139930
39435690	39435713	19	-	26472758	KBM7	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-3.6965242103752187	[582,545]	[10,28]	-9	hSpCas9	negative selection	331039
39435621	39435644	19	+	26472758	KBM7	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-2.815079500818306	[850,859]	[76,39]	-9	hSpCas9	negative selection	331040
39433688	39433711	19	-	26472758	KBM7	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-1.9292960690141758	[691,417]	[45,85]	-8	hSpCas9	negative selection	331041
39435862	39435885	19	-	26472758	KBM7	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	-0.26541087125049145	[164,240]	[131,35]	-3	hSpCas9	negative selection	331042
39435606	39435629	19	-	26472758	KBM7	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.1807229057169453	[1839,1391]	[240,98]	-8	hSpCas9	negative selection	331043
39433654	39433677	19	+	26472758	KBM7	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.011562358097397363	[2046,1689]	[937,803]	0	hSpCas9	negative selection	331044
39433282	39433305	19	+	26472758	KBM7	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-5.696838715143508	[149,76]	[0,0]	-9	hSpCas9	negative selection	331045
39433338	39433361	19	+	26472758	KBM7	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-2.4483062751383047	[466,459]	[9,66]	-9	hSpCas9	negative selection	331046
39433323	39433346	19	+	26472758	KBM7	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.2630249031720615	[1299,1290]	[757,712]	2	hSpCas9	negative selection	331047
39435883	39435906	19	-	26472758	KBM7	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-2.335187222744211	[376,297]	[26,34]	-9	hSpCas9	negative selection	331048
39435690	39435713	19	-	26472758	Raji	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-4.466263652119722	[380]	[3]	-9	hSpCas9	negative selection	522157
39435621	39435644	19	+	26472758	Raji	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-3.281807786418441	[460]	[10]	-9	hSpCas9	negative selection	522158
39433688	39433711	19	-	26472758	Raji	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-3.8790273998784457	[316]	[4]	-9	hSpCas9	negative selection	522159
39435862	39435885	19	-	26472758	Raji	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	1.4760281291679922	[78]	[50]	9	hSpCas9	negative selection	522160
39435606	39435629	19	-	26472758	Raji	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-3.477578965347557	[719]	[14]	-9	hSpCas9	negative selection	522161
39433654	39433677	19	+	26472758	Raji	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	0.03128055628780757	[1011]	[239]	0	hSpCas9	negative selection	522162
39433282	39433305	19	+	26472758	Raji	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-3.2501684692444845	[40]	[0]	-9	hSpCas9	negative selection	522163
39433338	39433361	19	+	26472758	Raji	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-2.2750861014488137	[291]	[13]	-9	hSpCas9	negative selection	522164
39433323	39433346	19	+	26472758	Raji	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.22459914924545488	[637]	[172]	2	hSpCas9	negative selection	522165
39435883	39435906	19	-	26472758	Raji	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-2.82807621243169	[152]	[4]	-9	hSpCas9	negative selection	522166
39435690	39435713	19	-	26472758	K562	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-3.2999017885573636	[594]	[50]	-8	hSpCas9	negative selection	713275
39435621	39435644	19	+	26472758	K562	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-3.5502623643560467	[679]	[48]	-8	hSpCas9	negative selection	713276
39433688	39433711	19	-	26472758	K562	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-4.2686508545729245	[410]	[17]	-9	hSpCas9	negative selection	713277
39435862	39435885	19	-	26472758	K562	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	-0.1747348800846289	[233]	[174]	-1	hSpCas9	negative selection	713278
39435606	39435629	19	-	26472758	K562	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.4125952658422976	[1128]	[178]	-8	hSpCas9	negative selection	713279
39433654	39433677	19	+	26472758	K562	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.5110150222945775	[1650]	[977]	-3	hSpCas9	negative selection	713280
39433282	39433305	19	+	26472758	K562	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-5.18184602703565	[42]	[0]	-9	hSpCas9	negative selection	713281
39433338	39433361	19	+	26472758	K562	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-4.88486428927852	[384]	[10]	-9	hSpCas9	negative selection	713282
39433323	39433346	19	+	26472758	K562	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.13791372990592277	[1081]	[1004]	1	hSpCas9	negative selection	713283
39435883	39435906	19	-	26472758	K562	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-2.4902908925593916	[212]	[31]	-8	hSpCas9	negative selection	713284
39433639	39433662	19	-	26627737	DLD1	viability	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	0.43027084725355835	[106]	[20,15,89]	4	hSpCas9	negative selection	804691
39433639	39433662	19	-	26627737	GBM cells	viability after 5 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	0.42186671333141723	[102]	[76,70]	6	hSpCas9	negative selection	887006
39433639	39433662	19	-	26627737	GBM cells	viability after 13 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	0.6503252426470714	[102]	[138,45]	7	hSpCas9	negative selection	969321
39433639	39433662	19	-	26627737	GBM cells	viability after 21 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	0.4431359731949013	[102]	[85,66]	4	hSpCas9	negative selection	1051636
39433639	39433662	19	-	26627737	RPE1	viability after 9 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	0.07390872309528085	[216]	[74,66]	0	hSpCas9	negative selection	1133951
39433639	39433662	19	-	26627737	RPE1	viability after 12 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	-1.5189894067499101	[216]	[14,25]	-8	hSpCas9	negative selection	1216266
39433639	39433662	19	-	26627737	RPE1	viability after 15 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	1.1637940147087322	[216]	[163,111]	6	hSpCas9	negative selection	1298581
39433639	39433662	19	-	26627737	RPE1	viability after 18 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	-0.6730015660019597	[216]	[57,13]	-4	hSpCas9	negative selection	1380896
39433639	39433662	19	-	26627737	HeLa	viability after 8 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	2.5476001904175876	[39]	[31,171,86]	9	hSpCas9	negative selection	1463211
39433639	39433662	19	-	26627737	HeLa	viability after 12 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	1.6468966748837888	[39]	[36,59,56]	9	hSpCas9	negative selection	1545526
39433639	39433662	19	-	26627737	HeLa	viability after 15 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	2.088669236637552	[39]	[19,63,128]	9	hSpCas9	negative selection	1627841
39433639	39433662	19	-	26627737	HeLa	viability after 18 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	2.111886100320387	[39]	[13,54,128]	9	hSpCas9	negative selection	1710156
39433639	39433662	19	-	26627737	HCT116	viability after 6 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	1.5588273877039198	[174]	[169,31]	7	hSpCas9	negative selection	1792471
39433639	39433662	19	-	26627737	HCT116	viability after 8 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	1.1628968015300838	[66]	[57,143,45]	8	hSpCas9	negative selection	1874786
39433639	39433662	19	-	26627737	HCT116	viability after 9 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	1.386325993831892	[174]	[72,160]	8	hSpCas9	negative selection	1957101
39433639	39433662	19	-	26627737	HCT116	viability after 12 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	0.8960683350006833	[66]	[17,116,66]	7	hSpCas9	negative selection	2039416
39433639	39433662	19	-	26627737	HCT116	viability after 15 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	1.1881673480338768	[66]	[56,89,111]	8	hSpCas9	negative selection	2121731
39433639	39433662	19	-	26627737	HCT116	viability after 18 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	1.3267351798644995	[66]	[48,117,73]	8	hSpCas9	negative selection	2204046
39433261	39433284	19	+	24336569	HL60	viability	GTCACGATGGGCTTATCGGTAGG	RPS16	ENSG00000105193	-4.562237751078082	[680]	[60]	-9	hSpCas9	negative selection	2292248
39433269	39433292	19	+	24336569	HL60	viability	GGGCTTATCGGTAGGATTTCTGG	RPS16	ENSG00000105193	-0.7575744894082477	[734]	[919]	-6	hSpCas9	negative selection	2292249
39433281	39433304	19	+	24336569	HL60	viability	AGGATTTCTGGTAGCGAGCGCGG	RPS16	ENSG00000105193	-0.641932039429304	[72]	[98]	-5	hSpCas9	negative selection	2292250
39433289	39433312	19	+	24336569	HL60	viability	TGGTAGCGAGCGCGGGCACCAGG	RPS16	ENSG00000105193	-0.4965015999077402	[499]	[749]	-4	hSpCas9	negative selection	2292251
39433338	39433361	19	+	24336569	HL60	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.6502293738222513	[619]	[835]	-5	hSpCas9	negative selection	2292252
39433344	39433367	19	+	24336569	HL60	viability	GGTCAGCTACCAGCAGGGTCCGG	RPS16	ENSG00000105193	-1.7117404946451509	[759]	[490]	-9	hSpCas9	negative selection	2292253
39433353	39433376	19	+	24336569	HL60	viability	CCAGCAGGGTCCGGTCATACTGG	RPS16	ENSG00000105193	-0.6650168343241829	[1789]	[2388]	-6	hSpCas9	negative selection	2292254
39433359	39433382	19	+	24336569	HL60	viability	GGGTCCGGTCATACTGGATGAGG	RPS16	ENSG00000105193	-2.7439797456352215	[534]	[168]	-9	hSpCas9	negative selection	2292255
39433381	39433404	19	+	24336569	HL60	viability	GATGTCTTTGATCTCCTTCTTGG	RPS16	ENSG00000105193	-0.14650322235638769	[793]	[1517]	-1	hSpCas9	negative selection	2292256
39433395	39433418	19	-	24336569	HL60	viability	TGTGGATGAGGCTTCCAAGAAGG	RPS16	ENSG00000105193	-0.9706081812305682	[913]	[986]	-7	hSpCas9	negative selection	2292257
39433400	39433423	19	+	24336569	HL60	viability	TTGGAAGCCTCATCCACATCTGG	RPS16	ENSG00000105193	-0.7606130457623581	[1071]	[1338]	-6	hSpCas9	negative selection	2292258
39433407	39433430	19	-	24336569	HL60	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.19182454807140184	[515]	[955]	-2	hSpCas9	negative selection	2292259
39433507	39433530	19	+	24336569	HL60	viability	CCCATGCTCACTCACATTTCTGG	RPS16	ENSG00000105193	0.011198856276154023	[1009]	[2153]	0	hSpCas9	negative selection	2292260
39433514	39433537	19	+	24336569	HL60	viability	TCACTCACATTTCTGGTAATAGG	RPS16	ENSG00000105193	-1.2111197625561463	[604]	[552]	-8	hSpCas9	negative selection	2292261
39433522	39433545	19	+	24336569	HL60	viability	ATTTCTGGTAATAGGCCACCAGG	RPS16	ENSG00000105193	0.2883441446569499	[485]	[1255]	2	hSpCas9	negative selection	2292262
39433529	39433552	19	+	24336569	HL60	viability	GTAATAGGCCACCAGGGCTTTGG	RPS16	ENSG00000105193	-1.3114697060752196	[474]	[404]	-8	hSpCas9	negative selection	2292263
39433535	39433558	19	+	24336569	HL60	viability	GGCCACCAGGGCTTTGGAGATGG	RPS16	ENSG00000105193	-0.7285830774126216	[82]	[105]	-6	hSpCas9	negative selection	2292264
39433540	39433563	19	-	24336569	HL60	viability	TCAGTCCATCTCCAAAGCCCTGG	RPS16	ENSG00000105193	-2.9352433597778527	[299]	[82]	-9	hSpCas9	negative selection	2292265
39433653	39433676	19	+	24336569	HL60	viability	CCTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-0.5261724665840829	[261]	[384]	-5	hSpCas9	negative selection	2292266
39433664	39433687	19	-	24336569	HL60	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.274759455423049	[847]	[2170]	2	hSpCas9	negative selection	2292267
39433677	39433700	19	-	24336569	HL60	viability	TGTAAAGGGTGGTGGTCACGTGG	RPS16	ENSG00000105193	-1.0076681712942488	[704]	[741]	-7	hSpCas9	negative selection	2292268
39433685	39433708	19	-	24336569	HL60	viability	CGTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-0.7549992251447619	[507]	[636]	-6	hSpCas9	negative selection	2292269
39433691	39433714	19	-	24336569	HL60	viability	GACATCCGTGTCCGTGTAAAGGG	RPS16	ENSG00000105193	-0.4283865749831284	[392]	[617]	-4	hSpCas9	negative selection	2292270
39433718	39433741	19	-	24336569	HL60	viability	CTCGGCAAGGAGCGATTTGCTGG	RPS16	ENSG00000105193	0.45762696718605167	[915]	[2661]	4	hSpCas9	negative selection	2292271
39433730	39433753	19	+	24336569	HL60	viability	TCCTTGCCGAGAAGCAGAACTGG	RPS16	ENSG00000105193	-0.5934197431835198	[235]	[330]	-5	hSpCas9	negative selection	2292272
39433736	39433759	19	-	24336569	HL60	viability	CTGGAGCCAGTTCTGCTTCTCGG	RPS16	ENSG00000105193	0.16981929951253988	[338]	[806]	1	hSpCas9	negative selection	2292273
39435605	39435628	19	+	24336569	HL60	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-0.4879177536870448	[390]	[589]	-4	hSpCas9	negative selection	2292274
39435621	39435644	19	+	24336569	HL60	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-2.531147742714632	[294]	[107]	-9	hSpCas9	negative selection	2292275
39435646	39435669	19	-	24336569	HL60	viability	GTCTCATCAAGGTGAACGGGCGG	RPS16	ENSG00000105193	-2.170161446604183	[1022]	[480]	-9	hSpCas9	negative selection	2292276
39435657	39435680	19	-	24336569	HL60	viability	ACGCGGCAATGGTCTCATCAAGG	RPS16	ENSG00000105193	-1.154253520640782	[751]	[714]	-8	hSpCas9	negative selection	2292277
39435668	39435691	19	-	24336569	HL60	viability	GCGCACTGCAAACGCGGCAATGG	RPS16	ENSG00000105193	-0.13238803579156866	[345]	[667]	-1	hSpCas9	negative selection	2292278
39435674	39435697	19	-	24336569	HL60	viability	GCTGTGGCGCACTGCAAACGCGG	RPS16	ENSG00000105193	-3.020063555964753	[643]	[167]	-9	hSpCas9	negative selection	2292279
39435690	39435713	19	-	24336569	HL60	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-1.2975010269255207	[452]	[389]	-8	hSpCas9	negative selection	2292280
39435847	39435870	19	-	24336569	HL60	viability	TGTGCAGGTCTTCGGACGCAAGG	RPS16	ENSG00000105193	-0.1895817174842065	[553]	[1027]	-2	hSpCas9	negative selection	2292281
39435855	39435878	19	-	24336569	HL60	viability	CTGCAGTCTGTGCAGGTCTTCGG	RPS16	ENSG00000105193	0.15760706185418183	[171]	[405]	1	hSpCas9	negative selection	2292282
39435862	39435885	19	-	24336569	HL60	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	-0.40749659384899517	[219]	[350]	-4	hSpCas9	negative selection	2292283
39435870	39435893	19	+	24336569	HL60	viability	GACTGCAGCGGGCCCTTGGACGG	RPS16	ENSG00000105193	-3.6384122251804563	[152]	[25]	-9	hSpCas9	negative selection	2292284
39435875	39435898	19	+	24336569	HL60	viability	CAGCGGGCCCTTGGACGGCATGG	RPS16	ENSG00000105193	-1.1934907183630077	[347]	[321]	-8	hSpCas9	negative selection	2292285
39435882	39435905	19	-	24336569	HL60	viability	CTCGGAGCCATGCCGTCCAAGGG	RPS16	ENSG00000105193	-0.2745744890223147	[442]	[774]	-2	hSpCas9	negative selection	2292286
39433261	39433284	19	+	24336569	KBM7	viability	GTCACGATGGGCTTATCGGTAGG	RPS16	ENSG00000105193	-4.289397528174708	[465]	[64]	-9	hSpCas9	negative selection	2359425
39433269	39433292	19	+	24336569	KBM7	viability	GGGCTTATCGGTAGGATTTCTGG	RPS16	ENSG00000105193	0.9438137180015794	[222]	[1169]	7	hSpCas9	negative selection	2359426
39433281	39433304	19	+	24336569	KBM7	viability	AGGATTTCTGGTAGCGAGCGCGG	RPS16	ENSG00000105193	-2.839896619327643	[125]	[47]	-9	hSpCas9	negative selection	2359427
39433289	39433312	19	+	24336569	KBM7	viability	TGGTAGCGAGCGCGGGCACCAGG	RPS16	ENSG00000105193	-0.3583616074143991	[289]	[616]	-3	hSpCas9	negative selection	2359428
39433338	39433361	19	+	24336569	KBM7	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-5.151713398247717	[390]	[29]	-9	hSpCas9	negative selection	2359429
39433344	39433367	19	+	24336569	KBM7	viability	GGTCAGCTACCAGCAGGGTCCGG	RPS16	ENSG00000105193	-3.1249492310366875	[821]	[256]	-9	hSpCas9	negative selection	2359430
39433353	39433376	19	+	24336569	KBM7	viability	CCAGCAGGGTCCGGTCATACTGG	RPS16	ENSG00000105193	0.35937702575742403	[1033]	[3617]	3	hSpCas9	negative selection	2359431
39433359	39433382	19	+	24336569	KBM7	viability	GGGTCCGGTCATACTGGATGAGG	RPS16	ENSG00000105193	-4.110544209271311	[626]	[98]	-9	hSpCas9	negative selection	2359432
39433381	39433404	19	+	24336569	KBM7	viability	GATGTCTTTGATCTCCTTCTTGG	RPS16	ENSG00000105193	0.06796698057928863	[666]	[1906]	0	hSpCas9	negative selection	2359433
39433395	39433418	19	-	24336569	KBM7	viability	TGTGGATGAGGCTTCCAAGAAGG	RPS16	ENSG00000105193	-2.386943398810088	[628]	[327]	-8	hSpCas9	negative selection	2359434
39433400	39433423	19	+	24336569	KBM7	viability	TTGGAAGCCTCATCCACATCTGG	RPS16	ENSG00000105193	-1.2053190835664505	[885]	[1047]	-7	hSpCas9	negative selection	2359435
39433407	39433430	19	-	24336569	KBM7	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-1.1668637841725389	[418]	[508]	-7	hSpCas9	negative selection	2359436
39433507	39433530	19	+	24336569	KBM7	viability	CCCATGCTCACTCACATTTCTGG	RPS16	ENSG00000105193	0.914030163276772	[458]	[2358]	7	hSpCas9	negative selection	2359437
39433514	39433537	19	+	24336569	KBM7	viability	TCACTCACATTTCTGGTAATAGG	RPS16	ENSG00000105193	-0.13391871764512053	[314]	[782]	-1	hSpCas9	negative selection	2359438
39433522	39433545	19	+	24336569	KBM7	viability	ATTTCTGGTAATAGGCCACCAGG	RPS16	ENSG00000105193	-0.25476335515231463	[527]	[1206]	-2	hSpCas9	negative selection	2359439
39433529	39433552	19	+	24336569	KBM7	viability	GTAATAGGCCACCAGGGCTTTGG	RPS16	ENSG00000105193	-2.089850380233673	[397]	[254]	-8	hSpCas9	negative selection	2359440
39433535	39433558	19	+	24336569	KBM7	viability	GGCCACCAGGGCTTTGGAGATGG	RPS16	ENSG00000105193	-3.5075613013771147	[220]	[52]	-9	hSpCas9	negative selection	2359441
39433540	39433563	19	-	24336569	KBM7	viability	TCAGTCCATCTCCAAAGCCCTGG	RPS16	ENSG00000105193	-5.23417555843969	[68]	[4]	-9	hSpCas9	negative selection	2359442
39433653	39433676	19	+	24336569	KBM7	viability	CCTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	1.3829210621565826	[105]	[753]	9	hSpCas9	negative selection	2359443
39433664	39433687	19	-	24336569	KBM7	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.3895230689027738	[479]	[1714]	3	hSpCas9	negative selection	2359444
39433677	39433700	19	-	24336569	KBM7	viability	TGTAAAGGGTGGTGGTCACGTGG	RPS16	ENSG00000105193	-1.3783816861898563	[691]	[725]	-7	hSpCas9	negative selection	2359445
39433685	39433708	19	-	24336569	KBM7	viability	CGTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-0.6568423459416958	[236]	[409]	-5	hSpCas9	negative selection	2359446
39433691	39433714	19	-	24336569	KBM7	viability	GACATCCGTGTCCGTGTAAAGGG	RPS16	ENSG00000105193	-0.16547323820197823	[381]	[928]	-1	hSpCas9	negative selection	2359447
39433718	39433741	19	-	24336569	KBM7	viability	CTCGGCAAGGAGCGATTTGCTGG	RPS16	ENSG00000105193	0.5031500099931605	[550]	[2129]	4	hSpCas9	negative selection	2359448
39433730	39433753	19	+	24336569	KBM7	viability	TCCTTGCCGAGAAGCAGAACTGG	RPS16	ENSG00000105193	-1.323904826162327	[323]	[352]	-7	hSpCas9	negative selection	2359449
39433736	39433759	19	-	24336569	KBM7	viability	CTGGAGCCAGTTCTGCTTCTCGG	RPS16	ENSG00000105193	-0.565526907213677	[413]	[762]	-4	hSpCas9	negative selection	2359450
39435605	39435628	19	+	24336569	KBM7	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.7589380497260576	[509]	[410]	-8	hSpCas9	negative selection	2359451
39435621	39435644	19	+	24336569	KBM7	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-7.338350126794124	[177]	[2]	-9	hSpCas9	negative selection	2359452
39435646	39435669	19	-	24336569	KBM7	viability	GTCTCATCAAGGTGAACGGGCGG	RPS16	ENSG00000105193	-4.773703208230724	[1032]	[102]	-9	hSpCas9	negative selection	2359453
39435657	39435680	19	-	24336569	KBM7	viability	ACGCGGCAATGGTCTCATCAAGG	RPS16	ENSG00000105193	-2.0756104191619245	[628]	[406]	-8	hSpCas9	negative selection	2359454
39435668	39435691	19	-	24336569	KBM7	viability	GCGCACTGCAAACGCGGCAATGG	RPS16	ENSG00000105193	-2.798908207876804	[346]	[135]	-9	hSpCas9	negative selection	2359455
39435674	39435697	19	-	24336569	KBM7	viability	GCTGTGGCGCACTGCAAACGCGG	RPS16	ENSG00000105193	-6.190971059874522	[374]	[13]	-9	hSpCas9	negative selection	2359456
39435690	39435713	19	-	24336569	KBM7	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-3.928314328394402	[306]	[54]	-9	hSpCas9	negative selection	2359457
39435847	39435870	19	-	24336569	KBM7	viability	TGTGCAGGTCTTCGGACGCAAGG	RPS16	ENSG00000105193	-0.7013913893357993	[498]	[836]	-5	hSpCas9	negative selection	2359458
39435855	39435878	19	-	24336569	KBM7	viability	CTGCAGTCTGTGCAGGTCTTCGG	RPS16	ENSG00000105193	0.6007838250125164	[65]	[272]	5	hSpCas9	negative selection	2359459
39435862	39435885	19	-	24336569	KBM7	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	-0.6124332084437729	[212]	[379]	-5	hSpCas9	negative selection	2359460
39435870	39435893	19	+	24336569	KBM7	viability	GACTGCAGCGGGCCCTTGGACGG	RPS16	ENSG00000105193	-1.3002374804736956	[92]	[102]	-7	hSpCas9	negative selection	2359461
39435875	39435898	19	+	24336569	KBM7	viability	CAGCGGGCCCTTGGACGGCATGG	RPS16	ENSG00000105193	-2.3955324487792877	[244]	[126]	-8	hSpCas9	negative selection	2359462
39435882	39435905	19	-	24336569	KBM7	viability	CTCGGAGCCATGCCGTCCAAGGG	RPS16	ENSG00000105193	-1.092274964456478	[375]	[480]	-7	hSpCas9	negative selection	2359463
39433681	39433704	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTGACCACCACCCTTTACACGG	RPS16	ENSG00000105193	-0.5965062895415291	[2,3]	[1,0]	-7	hSpCas9	positive selection	3017877
39435623	39435646	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-0.13390318486350566	[3,3]	[3,1]	-2	hSpCas9	positive selection	3017878
39435674	39435697	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGTGGCGCACTGCAAACGCGG	RPS16	ENSG00000105193	-0.17058804155254825	[0,1]	[0,0]	-2	hSpCas9	positive selection	3017879
39435646	39435669	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCTCATCAAGGTGAACGGGCGG	RPS16	ENSG00000105193	-0.9021058784983955	[2,2]	[1,0]	-8	hSpCas9	positive selection	3017880
39433681	39433704	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTGACCACCACCCTTTACACGG	RPS16	ENSG00000105193	-0.5410321091886066	[2,2]	[1,0]	-7	hSpCas9	positive selection	3085735
39435623	39435646	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-0.45560477403177696	[3,3]	[2,0]	-6	hSpCas9	positive selection	3085736
39435674	39435697	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGTGGCGCACTGCAAACGCGG	RPS16	ENSG00000105193	0.2491592948949044	[0,0]	[0,0]	4	hSpCas9	positive selection	3085737
39435646	39435669	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCTCATCAAGGTGAACGGGCGG	RPS16	ENSG00000105193	0.4135714478647675	[2,2]	[3,1]	7	hSpCas9	positive selection	3085738
39435606	39435629		-	24336571	A375	resistance to PLX after 7 days	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	0.14840625408037775	[10,8]	[10,11]	5	hSpCas9	positive selection	3141826
39433664	39433687		-	24336571	A375	resistance to PLX after 7 days	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.04819205305192153	[13,11]	[12,13]	1	hSpCas9	positive selection	3141827
39435606	39435629		-	24336571	A375	resistance to PLX after 14 days	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.10405848206809065	[9,9]	[3,3]	-1	hSpCas9	positive selection	3199619
39433664	39433687		-	24336571	A375	resistance to PLX after 14 days	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.8275412423354019	[12,9]	[7,10]	7	hSpCas9	positive selection	3199620
39435606	39435629		-	24336571	A375	viability after 7 days	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.5985176102459112	[15]	[10,8]	-7	hSpCas9	negative selection	3257412
39433664	39433687		-	24336571	A375	viability after 7 days	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.6646645537057544	[7]	[13,11]	8	hSpCas9	negative selection	3257413
39435606	39435629		-	24336571	A375	viability after 14 days	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.6121355967612008	[15]	[9,9]	-6	hSpCas9	negative selection	3315205
39433664	39433687		-	24336571	A375	viability after 14 days	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.5405223293683489	[7]	[12,9]	7	hSpCas9	negative selection	3315206
39435605	39435628	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	2.672363710724679	[23,23]	[0,0]	8	hSpCas9	positive selection	3390596
39433407	39433430	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.537089654904271	[221,221]	[0,0]	-4	hSpCas9	positive selection	3390597
39433338	39433361	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	1.5024387092823666	[53,53]	[0,0]	6	hSpCas9	positive selection	3390598
39433680	39433703	19	+	26780180	HT29	viability (Avana library 4 designs)	CGTGACCACCACCCTTTACACGG	RPS16	ENSG00000105193	3.48959586107171	[]	[]	9	hSpCas9	negative selection	3456258
39435622	39435645	19	+	26780180	HT29	viability (Avana library 4 designs)	GCGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	4.20227264257348	[]	[]	9	hSpCas9	negative selection	3456259
39435674	39435697	19	-	26780180	HT29	viability (Avana library 4 designs)	GCTGTGGCGCACTGCAAACGCGG	RPS16	ENSG00000105193	5.05983517545043	[]	[]	9	hSpCas9	negative selection	3456260
39435646	39435669	19	-	26780180	HT29	viability (Avana library 4 designs)	GTCTCATCAAGGTGAACGGGCGG	RPS16	ENSG00000105193	5.96546893468687	[]	[]	9	hSpCas9	negative selection	3456261
39435622	39435645	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-11.241857054386	[]	[]	-8	hSpCas9	negative selection	3554646
39435674	39435697	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTGGCGCACTGCAAACGCGG	RPS16	ENSG00000105193	-14.7907819852336	[]	[]	-9	hSpCas9	negative selection	3554647
39435646	39435669	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTCTCATCAAGGTGAACGGGCGG	RPS16	ENSG00000105193	-13.7240241636674	[]	[]	-8	hSpCas9	negative selection	3554648
39433680	39433703	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGTGACCACCACCCTTTACACGG	RPS16	ENSG00000105193	-0.989907780608486	[]	[]	-1	hSpCas9	negative selection	3554649
39435858	39435881	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGACCTGCACAGACTGCAGCGG	RPS16	ENSG00000105193	2.81188067574616	[]	[]	4	hSpCas9	negative selection	3554650
39435882	39435905	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTCGGAGCCATGCCGTCCAAGGG	RPS16	ENSG00000105193	0.756123807786309	[]	[]	1	hSpCas9	negative selection	3554651
39435622	39435645	19	+	26780180	A375	viability (Avana lentiGuide)	GCGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	33.2301599582894	[]	[]	9	hSpCas9	negative selection	3663305
39435674	39435697	19	-	26780180	A375	viability (Avana lentiGuide)	GCTGTGGCGCACTGCAAACGCGG	RPS16	ENSG00000105193	25.7260083755757	[]	[]	9	hSpCas9	negative selection	3663306
39435646	39435669	19	-	26780180	A375	viability (Avana lentiGuide)	GTCTCATCAAGGTGAACGGGCGG	RPS16	ENSG00000105193	24.9034681246443	[]	[]	9	hSpCas9	negative selection	3663307
39433680	39433703	19	+	26780180	A375	viability (Avana lentiGuide)	CGTGACCACCACCCTTTACACGG	RPS16	ENSG00000105193	16.2559109493064	[]	[]	8	hSpCas9	negative selection	3663308
39435858	39435881	19	+	26780180	A375	viability (Avana lentiGuide)	AAGACCTGCACAGACTGCAGCGG	RPS16	ENSG00000105193	7.70036548658566	[]	[]	6	hSpCas9	negative selection	3663309
39435882	39435905	19	-	26780180	A375	viability (Avana lentiGuide)	CTCGGAGCCATGCCGTCCAAGGG	RPS16	ENSG00000105193	19.608655016092	[]	[]	8	hSpCas9	negative selection	3663310
39435622	39435645	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-1.0126271438864263	[5]	[2,1]	-8	hSpCas9	positive selection	3771912
39435674	39435697	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTGGCGCACTGCAAACGCGG	RPS16	ENSG00000105193	-2.2427075502291567	[3]	[0,0]	-9	hSpCas9	positive selection	3771913
39435646	39435669	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCTCATCAAGGTGAACGGGCGG	RPS16	ENSG00000105193	-1.2075982588163927	[5]	[2,0]	-9	hSpCas9	positive selection	3771914
39433680	39433703	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTGACCACCACCCTTTACACGG	RPS16	ENSG00000105193	0.14006609386728153	[5]	[6,5]	4	hSpCas9	positive selection	3771915
39435858	39435881	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGACCTGCACAGACTGCAGCGG	RPS16	ENSG00000105193	0.32822938943287033	[4]	[5,4]	8	hSpCas9	positive selection	3771916
39435882	39435905	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCGGAGCCATGCCGTCCAAGGG	RPS16	ENSG00000105193	0.15661505910060255	[5]	[6,5]	4	hSpCas9	positive selection	3771917
39435622	39435645	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-0.8424601918608291	[6]	[1,3]	-8	hSpCas9	positive selection	3880519
39435674	39435697	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTGGCGCACTGCAAACGCGG	RPS16	ENSG00000105193	-1.9913611019402702	[4]	[0,0]	-9	hSpCas9	positive selection	3880520
39435646	39435669	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCTCATCAAGGTGAACGGGCGG	RPS16	ENSG00000105193	-0.9514421559719598	[5]	[3,0]	-8	hSpCas9	positive selection	3880521
39433680	39433703	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTGACCACCACCCTTTACACGG	RPS16	ENSG00000105193	-0.7726096679966427	[5]	[2,2]	-7	hSpCas9	positive selection	3880522
39435858	39435881	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGACCTGCACAGACTGCAGCGG	RPS16	ENSG00000105193	6.21338926011239e-05	[4]	[4,3]	0	hSpCas9	positive selection	3880523
39435882	39435905	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCGGAGCCATGCCGTCCAAGGG	RPS16	ENSG00000105193	-0.6139881541776737	[6]	[2,3]	-7	hSpCas9	positive selection	3880524
39435605	39435628	19	+	26780180	A375	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	2.03997115810968	[]	[]	9	hSpCas9	negative selection	3990563
39433654	39433677	19	+	26780180	A375	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	1.98197883447681	[]	[]	9	hSpCas9	negative selection	3990564
39433407	39433430	19	-	26780180	A375	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	1.93892397268828	[]	[]	9	hSpCas9	negative selection	3990565
39433338	39433361	19	+	26780180	A375	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	1.36038171463913	[]	[]	7	hSpCas9	negative selection	3990566
39435606	39435629	19	-	26780180	A375	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	2.03766908347372	[]	[]	9	hSpCas9	negative selection	3990567
39433664	39433687	19	-	26780180	A375	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.618575195894942	[]	[]	2	hSpCas9	negative selection	3990568
39435605	39435628	19	+	26780180	HT29	viability (GeCKOv2 library)	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	2.90034883927578	[]	[]	9	hSpCas9	negative selection	4098529
39433654	39433677	19	+	26780180	HT29	viability (GeCKOv2 library)	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	1.79104574121294	[]	[]	8	hSpCas9	negative selection	4098530
39433407	39433430	19	-	26780180	HT29	viability (GeCKOv2 library)	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	1.71150206752774	[]	[]	8	hSpCas9	negative selection	4098531
39433338	39433361	19	+	26780180	HT29	viability (GeCKOv2 library)	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	1.21459224640101	[]	[]	6	hSpCas9	negative selection	4098532
39435606	39435629	19	-	26780180	HT29	viability (GeCKOv2 library)	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	2.0897134641091	[]	[]	9	hSpCas9	negative selection	4098533
39433664	39433687	19	-	26780180	HT29	viability (GeCKOv2 library)	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.139226644665801	[]	[]	0	hSpCas9	negative selection	4098534
39435606	39435629	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.19006720141919034	[3]	[2,1]	-4	hSpCas9	positive selection	4167510
39433664	39433687	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.3230283688338226	[3]	[2,3]	7	hSpCas9	positive selection	4167511
39435606	39435629	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.8437441190458619	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4231532
39433664	39433687	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	1.374450000763128	[3]	[5,3,2,3]	9	hSpCas9	positive selection	4231533
39435606	39435629	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.21357533498150336	[4]	[3,1]	-4	hSpCas9	positive selection	4295714
39433664	39433687	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.40011290212075884	[2]	[3,2]	7	hSpCas9	positive selection	4295715
39433654	39433677	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.20058429293398317	[2]	[1,1]	-4	hSpCas9	positive selection	4295716
39435605	39435628	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.0369168260925445	[2]	[1,0]	-9	hSpCas9	positive selection	4359967
39433407	39433430	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.02680455498641976	[3]	[3,2]	0	hSpCas9	positive selection	4359968
39433338	39433361	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.11472416654241963	[2]	[1,1]	-2	hSpCas9	positive selection	4359969
39433654	39433676	19	+	27760321	OCIAML3	viability	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-0.46875147953405216	[265,225]	[128,150]	-5	hSpCas9	negative selection	4435865
39433685	39433707	19	-	27760321	OCIAML3	viability	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-0.5733825567850055	[332,312]	[211,114]	-5	hSpCas9	negative selection	4435866
39435606	39435628	19	-	27760321	OCIAML3	viability	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.9029447513031281	[529,387]	[121,59]	-9	hSpCas9	negative selection	4435867
39435623	39435645	19	+	27760321	OCIAML3	viability	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-1.2501852258990955	[443,373]	[169,86]	-8	hSpCas9	negative selection	4435868
39433654	39433676	19	+	27760321	OCIAML2	viability	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-0.5941858045148862	[265,225]	[117,148]	-6	hSpCas9	negative selection	4519328
39433685	39433707	19	-	27760321	OCIAML2	viability	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-1.618190584115735	[332,312]	[79,91]	-8	hSpCas9	negative selection	4519329
39435606	39435628	19	-	27760321	OCIAML2	viability	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-3.0672334188609782	[529,387]	[39,48]	-9	hSpCas9	negative selection	4519330
39435623	39435645	19	+	27760321	OCIAML2	viability	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-2.6759304277374567	[443,373]	[70,25]	-9	hSpCas9	negative selection	4519331
39433654	39433676	19	+	27760321	MV411	viability	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-0.04542107571244869	[265,225]	[121,208]	0	hSpCas9	negative selection	4602791
39433685	39433707	19	-	27760321	MV411	viability	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-1.4479186071244492	[332,312]	[62,100]	-7	hSpCas9	negative selection	4602792
39435606	39435628	19	-	27760321	MV411	viability	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.0886101341389574	[529,387]	[0,174]	-8	hSpCas9	negative selection	4602793
39435623	39435645	19	+	27760321	MV411	viability	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-2.1039587775179345	[443,373]	[0,154]	-8	hSpCas9	negative selection	4602794
39433654	39433676	19	+	27760321	HL60	viability	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-0.2211931299612464	[265,225]	[98,248]	-2	hSpCas9	negative selection	4686254
39433685	39433707	19	-	27760321	HL60	viability	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-1.127786572475401	[332,312]	[164,73]	-8	hSpCas9	negative selection	4686255
39435606	39435628	19	-	27760321	HL60	viability	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.4763591059240355	[529,387]	[132,133]	-8	hSpCas9	negative selection	4686256
39435623	39435645	19	+	27760321	HL60	viability	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-1.0463262348420708	[443,373]	[116,207]	-7	hSpCas9	negative selection	4686257
39433654	39433676	19	+	27760321	HT1080	viability	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-5.764116406890383	[225,176]	[0,1]	-8	hSpCas9	negative selection	4769717
39433685	39433707	19	-	27760321	HT1080	viability	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-6.187029652332342	[312,243]	[1,0]	-9	hSpCas9	negative selection	4769718
39435606	39435628	19	-	27760321	HT1080	viability	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-7.1047779533865345	[387,302]	[0,0]	-9	hSpCas9	negative selection	4769719
39435623	39435645	19	+	27760321	HT1080	viability	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-7.051593929525819	[373,291]	[0,0]	-9	hSpCas9	negative selection	4769720
39433654	39433676	19	+	27760321	HT29	viability after 7 days	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-0.6460499552379864	[225,176]	[192,127,178]	-7	hSpCas9	negative selection	4853180
39433685	39433707	19	-	27760321	HT29	viability after 7 days	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-1.6660121190159636	[312,243]	[219,96,38]	-9	hSpCas9	negative selection	4853181
39435606	39435628	19	-	27760321	HT29	viability after 7 days	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.72498311715542	[387,302]	[356,272,190]	-7	hSpCas9	negative selection	4853182
39435623	39435645	19	+	27760321	HT29	viability after 7 days	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-1.0398253844441467	[373,291]	[126,313,172]	-8	hSpCas9	negative selection	4853183
39433654	39433676	19	+	27760321	HT29	viability after 25 days	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-6.033421346327412	[225,176]	[7,0,0]	-9	hSpCas9	negative selection	4936643
39433685	39433707	19	-	27760321	HT29	viability after 25 days	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-3.9952279960053843	[312,243]	[1,55,0]	-9	hSpCas9	negative selection	4936644
39435606	39435628	19	-	27760321	HT29	viability after 25 days	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.5761808039304557	[387,302]	[55,177,171]	-7	hSpCas9	negative selection	4936645
39435623	39435645	19	+	27760321	HT29	viability after 25 days	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-2.809718973445545	[373,291]	[65,15,82]	-8	hSpCas9	negative selection	4936646
39433654	39433676	19	+	27760321	HT29	viability after 22 days	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-4.254777557760255	[225,176]	[0,14,20]	-9	hSpCas9	negative selection	5020106
39433685	39433707	19	-	27760321	HT29	viability after 22 days	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-4.674371125827791	[312,243]	[1,34,0]	-9	hSpCas9	negative selection	5020107
39435606	39435628	19	-	27760321	HT29	viability after 22 days	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.0261185348371937	[387,302]	[359,127,94]	-6	hSpCas9	negative selection	5020108
39435623	39435645	19	+	27760321	HT29	viability after 22 days	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-2.9947518260013166	[373,291]	[11,71,61]	-8	hSpCas9	negative selection	5020109
39433654	39433676	19	+	27760321	HT29	viability after 19 days	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-4.514604813899323	[225,176]	[17,0,11]	-9	hSpCas9	negative selection	5103569
39433685	39433707	19	-	27760321	HT29	viability after 19 days	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-8.314773039439823	[312,243]	[0,0,0]	-9	hSpCas9	negative selection	5103570
39435606	39435628	19	-	27760321	HT29	viability after 19 days	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.1105826036693665	[387,302]	[90,27,152]	-8	hSpCas9	negative selection	5103571
39435623	39435645	19	+	27760321	HT29	viability after 19 days	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-3.8338462522703387	[373,291]	[45,5,29]	-9	hSpCas9	negative selection	5103572
39433654	39433676	19	+	27760321	HT29	viability after 16 days	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-1.8180732193717646	[225,176]	[14,71,99]	-8	hSpCas9	negative selection	5187032
39433685	39433707	19	-	27760321	HT29	viability after 16 days	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-6.651006277606707	[312,243]	[0,6,0]	-9	hSpCas9	negative selection	5187033
39435606	39435628	19	-	27760321	HT29	viability after 16 days	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.5723347647345782	[387,302]	[124,32,233]	-8	hSpCas9	negative selection	5187034
39435623	39435645	19	+	27760321	HT29	viability after 16 days	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-2.174208517013007	[373,291]	[25,16,200]	-8	hSpCas9	negative selection	5187035
39433654	39433676	19	+	27760321	HT29	viability after 13 days	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-1.8385886410417063	[225,176]	[65,79,50]	-8	hSpCas9	negative selection	5270495
39433685	39433707	19	-	27760321	HT29	viability after 13 days	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-4.991407111038439	[312,243]	[25,3,0]	-9	hSpCas9	negative selection	5270496
39435606	39435628	19	-	27760321	HT29	viability after 13 days	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.3551023746739026	[387,302]	[132,229,109]	-8	hSpCas9	negative selection	5270497
39435623	39435645	19	+	27760321	HT29	viability after 13 days	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-2.0691755828817233	[373,291]	[58,69,143]	-8	hSpCas9	negative selection	5270498
39433654	39433676	19	+	27760321	HT29	viability after 10 days	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-0.7095236666234783	[225,176]	[114,238,110]	-7	hSpCas9	negative selection	5353958
39433685	39433707	19	-	27760321	HT29	viability after 10 days	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-2.6961754535195737	[312,243]	[19,129,13]	-9	hSpCas9	negative selection	5353959
39435606	39435628	19	-	27760321	HT29	viability after 10 days	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.79150460792157	[387,302]	[25,91,251]	-9	hSpCas9	negative selection	5353960
39435623	39435645	19	+	27760321	HT29	viability after 10 days	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-2.319720075682434	[373,291]	[66,153,31]	-9	hSpCas9	negative selection	5353961
39433654	39433676	19	+	27760321	MOLM13	viability	CTGGGACTCACCATAAATCTGG	RPS16	ENSG00000105193	-2.344919261599095	[265,225]	[3,46]	-8	hSpCas9	negative selection	5437421
39433685	39433707	19	-	27760321	MOLM13	viability	GTGTCCGTGTAAAGGGTGGTGG	RPS16	ENSG00000105193	-2.018615373462349	[332,312]	[17,67]	-8	hSpCas9	negative selection	5437422
39435606	39435628	19	-	27760321	MOLM13	viability	CCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.6655538773663463	[529,387]	[0,73]	-8	hSpCas9	negative selection	5437423
39435623	39435645	19	+	27760321	MOLM13	viability	CGCGGCTCAATCATCTCCAGGG	RPS16	ENSG00000105193	-4.941405054468407	[443,373]	[0,12]	-9	hSpCas9	negative selection	5437424
39435510	39435533	19	-	27661255	K562	viability	GGGGGGGCTGGCATCAGCAACGG	RPS16	ENSG00000105193	0.00407679867175148	[1204,1186]	[1176,771]	0	dCas9-KRAB	negative selection	5508534
39435767	39435790	19	-	27661255	K562	viability	GTCGGTGGGCAGGAATCTAGGGG	RPS16	ENSG00000105193	-0.6673787284196944	[886,780]	[515,338]	-8	dCas9-KRAB	negative selection	5508535
39435900	39435923	19	-	27661255	K562	viability	GAGGTTGTCTAGTCCACGCTCGG	RPS16	ENSG00000105193	-2.327886675631392	[689,671]	[75,135]	-9	dCas9-KRAB	negative selection	5508536
39435606	39435629	19	-	27260156	BXPC3	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.2983805527302321	[1196]	[938,982,793,1401]	-6	hSpCas9	negative selection	5568174
39433664	39433687	19	-	27260156	BXPC3	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.2838479480299173	[385]	[472,401,565,534]	6	hSpCas9	negative selection	5568175
39433654	39433677	19	+	27260156	BXPC3	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.3365353863026389	[427]	[315,404,257,446]	-6	hSpCas9	negative selection	5568176
39435605	39435628	19	+	27260156	BXPC3	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.1826370347890105	[411]	[181,167,174,240]	-9	hSpCas9	negative selection	5632427
39433407	39433430	19	-	27260156	BXPC3	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.5451571383402988	[929]	[519,714,748,694]	-8	hSpCas9	negative selection	5632428
39433338	39433361	19	+	27260156	BXPC3	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.7073195124477135	[247]	[164,134,152,184]	-8	hSpCas9	negative selection	5632429
39435606	39435629	19	-	27260156	A673	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.5429479307150555	[1196]	[985,959,944,1057]	-8	hSpCas9	negative selection	5689425
39433664	39433687	19	-	27260156	A673	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.2714028359065533	[385]	[607,457,534,648]	6	hSpCas9	negative selection	5689426
39433654	39433677	19	+	27260156	A673	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.2519017404785361	[427]	[563,273,539,361]	-6	hSpCas9	negative selection	5689427
39435605	39435628	19	+	27260156	A673	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-0.9809958103622998	[411]	[195,273,257,267]	-9	hSpCas9	negative selection	5753678
39433407	39433430	19	-	27260156	A673	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.3429404537916936	[929]	[1119,854,897,662]	-7	hSpCas9	negative selection	5753679
39433338	39433361	19	+	27260156	A673	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.5125759755899383	[247]	[243,169,209,215]	-8	hSpCas9	negative selection	5753680
39435606	39435629	19	-	27260156	A375	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.3347190486758143	[1196]	[548,630,586,468]	-9	hSpCas9	negative selection	5810676
39433664	39433687	19	-	27260156	A375	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.4118834694563215	[385]	[596,647,654,513]	6	hSpCas9	negative selection	5810677
39433654	39433677	19	+	27260156	A375	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.9962032443264286	[427]	[106,333,421,159]	-8	hSpCas9	negative selection	5810678
39435605	39435628	19	+	27260156	A375	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.9014014335044687	[411]	[126,278,105,34]	-9	hSpCas9	negative selection	5874929
39433407	39433430	19	-	27260156	A375	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.8487393825186939	[929]	[637,546,718,509]	-8	hSpCas9	negative selection	5874930
39433338	39433361	19	+	27260156	A375	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.5994764523169428	[247]	[270,101,158,216]	-7	hSpCas9	negative selection	5874931
39435606	39435629	19	-	27260156	COLO741	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.43687052456333386	[1196]	[1088,1281,1020]	-7	hSpCas9	negative selection	5931927
39433664	39433687	19	-	27260156	COLO741	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.5118237007863198	[385]	[745,792,581]	8	hSpCas9	negative selection	5931928
39433654	39433677	19	+	27260156	COLO741	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.09675287824333215	[427]	[648,489,412]	-2	hSpCas9	negative selection	5931929
39435605	39435628	19	+	27260156	COLO741	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.1020885938914355	[411]	[387,239,127]	-9	hSpCas9	negative selection	5996180
39433407	39433430	19	-	27260156	COLO741	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.3623039412874872	[929]	[1068,1067,665]	-6	hSpCas9	negative selection	5996181
39433338	39433361	19	+	27260156	COLO741	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.5477675940821113	[247]	[228,123,291]	-8	hSpCas9	negative selection	5996182
39435606	39435629	19	-	27260156	CAL120	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.113021828623417	[1196]	[736,762,574]	-9	hSpCas9	negative selection	6053178
39433664	39433687	19	-	27260156	CAL120	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.07299611568204883	[385]	[683,326,530]	1	hSpCas9	negative selection	6053179
39433654	39433677	19	+	27260156	CAL120	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	0.07207735936845805	[427]	[909,312,509]	1	hSpCas9	negative selection	6053180
39435605	39435628	19	+	27260156	CAL120	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-2.2407162824390445	[411]	[160,47,123]	-9	hSpCas9	negative selection	6117431
39433407	39433430	19	-	27260156	CAL120	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.6557334392744735	[929]	[878,824,524]	-7	hSpCas9	negative selection	6117432
39433338	39433361	19	+	27260156	CAL120	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-1.004412719155007	[247]	[182,82,198]	-8	hSpCas9	negative selection	6117433
39435606	39435629	19	-	27260156	CADOES1	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.9829644428117346	[1196]	[580,541,589,538]	-9	hSpCas9	negative selection	6174429
39433664	39433687	19	-	27260156	CADOES1	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.7008224468968646	[385]	[491,682,768,382]	9	hSpCas9	negative selection	6174430
39433654	39433677	19	+	27260156	CADOES1	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.4377672893141025	[427]	[298,264,328,281]	-6	hSpCas9	negative selection	6174431
39435605	39435628	19	+	27260156	CADOES1	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.790032743901883	[411]	[168,47,87,138]	-9	hSpCas9	negative selection	6238682
39433407	39433430	19	-	27260156	CADOES1	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.3570319671982145	[929]	[904,519,610,663]	-6	hSpCas9	negative selection	6238683
39433338	39433361	19	+	27260156	CADOES1	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.6273968712854573	[247]	[186,100,211,94]	-8	hSpCas9	negative selection	6238684
39435606	39435629	19	-	27260156	EWS502	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.7027123929723273	[1196]	[343,338,403,483]	-9	hSpCas9	negative selection	6295680
39433664	39433687	19	-	27260156	EWS502	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.3832618760843499	[385]	[283,604,611,667]	6	hSpCas9	negative selection	6295681
39433654	39433677	19	+	27260156	EWS502	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-1.3096956629024537	[427]	[126,156,254,201]	-9	hSpCas9	negative selection	6295682
39435605	39435628	19	+	27260156	EWS502	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-2.530936968053575	[411]	[47,120,41,92]	-9	hSpCas9	negative selection	6359933
39433407	39433430	19	-	27260156	EWS502	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.8361006057231882	[929]	[408,566,593,659]	-8	hSpCas9	negative selection	6359934
39433338	39433361	19	+	27260156	EWS502	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.7970103370321874	[247]	[164,217,120,90]	-8	hSpCas9	negative selection	6359935
39435606	39435629	19	-	27260156	EW8	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.6832306543147153	[1196]	[840,645,452,526]	-8	hSpCas9	negative selection	6416931
39433664	39433687	19	-	27260156	EW8	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.4949113376490383	[385]	[433,514,283,554]	8	hSpCas9	negative selection	6416932
39433654	39433677	19	+	27260156	EW8	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.4577663862459233	[427]	[266,270,145,344]	-7	hSpCas9	negative selection	6416933
39435605	39435628	19	+	27260156	EW8	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.520514575857445	[411]	[103,113,138,102]	-9	hSpCas9	negative selection	6481184
39433407	39433430	19	-	27260156	EW8	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.4596265984011083	[929]	[675,556,476,506]	-7	hSpCas9	negative selection	6481185
39433338	39433361	19	+	27260156	EW8	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.9646150398517758	[247]	[76,118,101,110]	-9	hSpCas9	negative selection	6481186
39435606	39435629	19	-	27260156	CORL105	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.7456741261734092	[1196]	[1139,712,896,615]	-8	hSpCas9	negative selection	6538182
39433664	39433687	19	-	27260156	CORL105	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.3421248820731714	[385]	[690,507,593,506]	6	hSpCas9	negative selection	6538183
39433654	39433677	19	+	27260156	CORL105	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.8109181818773559	[427]	[331,304,317,193]	-8	hSpCas9	negative selection	6538184
39435605	39435628	19	+	27260156	CORL105	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.0154365310158826	[411]	[289,228,235,200]	-9	hSpCas9	negative selection	6602435
39433407	39433430	19	-	27260156	CORL105	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.5359609848575732	[929]	[761,722,830,700]	-7	hSpCas9	negative selection	6602436
39433338	39433361	19	+	27260156	CORL105	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.6498773330475597	[247]	[114,250,263,118]	-8	hSpCas9	negative selection	6602437
39435606	39435629	19	-	27260156	HS294T	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.8150588030363518	[1196]	[147,211,327,398]	-8	hSpCas9	negative selection	6659433
39433664	39433687	19	-	27260156	HS294T	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.5914448560653935	[385]	[150,296,197,263]	7	hSpCas9	negative selection	6659434
39433654	39433677	19	+	27260156	HS294T	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.4665426948771389	[427]	[90,104,135,155]	-6	hSpCas9	negative selection	6659435
39435605	39435628	19	+	27260156	HS294T	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.7464982702131264	[411]	[40,26,70,52]	-9	hSpCas9	negative selection	6723686
39433407	39433430	19	-	27260156	HS294T	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.2023540335181444	[929]	[211,334,413,293]	-3	hSpCas9	negative selection	6723687
39433338	39433361	19	+	27260156	HS294T	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.9198305934752095	[247]	[28,71,36,68]	-8	hSpCas9	negative selection	6723688
39435606	39435629	19	-	27260156	HCC44	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.0007674724809132	[1196]	[673,562,874,639]	-8	hSpCas9	negative selection	6780684
39433664	39433687	19	-	27260156	HCC44	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.5965999579255545	[385]	[660,540,935,564]	8	hSpCas9	negative selection	6780685
39433654	39433677	19	+	27260156	HCC44	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.8246022369864778	[427]	[237,238,260,349]	-8	hSpCas9	negative selection	6780686
39435605	39435628	19	+	27260156	HCC44	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-2.5459996512109337	[411]	[62,68,181,23]	-9	hSpCas9	negative selection	6844937
39433407	39433430	19	-	27260156	HCC44	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-1.2015218777026129	[929]	[696,293,607,302]	-9	hSpCas9	negative selection	6844938
39433338	39433361	19	+	27260156	HCC44	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-1.2430059299592617	[247]	[157,115,117,85]	-9	hSpCas9	negative selection	6844939
39435606	39435629	19	-	27260156	G402	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.240265271635318	[1196]	[389,891,731,447]	-8	hSpCas9	negative selection	6901935
39433664	39433687	19	-	27260156	G402	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.4854578238955457	[385]	[664,739,775,468]	6	hSpCas9	negative selection	6901936
39433654	39433677	19	+	27260156	G402	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-1.0210622185359943	[427]	[486,266,154,157]	-8	hSpCas9	negative selection	6901937
39435605	39435628	19	+	27260156	G402	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-2.1268234892938196	[411]	[132,151,70,108]	-9	hSpCas9	negative selection	6966188
39433407	39433430	19	-	27260156	G402	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	0.0734093260963331	[929]	[803,1089,919,1861]	0	hSpCas9	negative selection	6966189
39433338	39433361	19	+	27260156	G402	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-1.6155483251374743	[247]	[43,124,93,123]	-9	hSpCas9	negative selection	6966190
39435606	39435629	19	-	27260156	L33	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	0.0806459106815487	[1196]	[1247,572,726,1259]	1	hSpCas9	negative selection	7023186
39433664	39433687	19	-	27260156	L33	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.2524160717933628	[385]	[552,165,234,503]	5	hSpCas9	negative selection	7023187
39433654	39433677	19	+	27260156	L33	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	0.3121085944122449	[427]	[525,202,316,598]	6	hSpCas9	negative selection	7023188
39435605	39435628	19	+	27260156	L33	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.3168550295270722	[411]	[159,59,125,154]	-9	hSpCas9	negative selection	7087439
39433407	39433430	19	-	27260156	L33	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.1030920929868182	[929]	[859,358,541,864]	-2	hSpCas9	negative selection	7087440
39433338	39433361	19	+	27260156	L33	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.36264680340595346	[247]	[226,45,119,239]	-7	hSpCas9	negative selection	7087441
39435606	39435629	19	-	27260156	K562	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.391626350746849	[1196]	[354,666,309,306]	-8	hSpCas9	negative selection	7144437
39433664	39433687	19	-	27260156	K562	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.46134492328944654	[385]	[563,519,455,366]	6	hSpCas9	negative selection	7144438
39433654	39433677	19	+	27260156	K562	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.6552721447238254	[427]	[420,192,225,146]	-6	hSpCas9	negative selection	7144439
39435605	39435628	19	+	27260156	K562	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-3.5982318894762484	[411]	[32,35,10,39]	-9	hSpCas9	negative selection	7208690
39433407	39433430	19	-	27260156	K562	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.9625367685868209	[929]	[387,744,326,264]	-8	hSpCas9	negative selection	7208691
39433338	39433361	19	+	27260156	K562	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	0.008387405980855078	[247]	[144,259,137,324]	0	hSpCas9	negative selection	7208692
39435606	39435629	19	-	27260156	HT29	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.423245717999363	[1196]	[598,510,560,501]	-9	hSpCas9	negative selection	7265688
39433664	39433687	19	-	27260156	HT29	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.4952131506291833	[385]	[678,843,690,467]	8	hSpCas9	negative selection	7265689
39433654	39433677	19	+	27260156	HT29	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.7235398487220044	[427]	[347,266,411,238]	-8	hSpCas9	negative selection	7265690
39435605	39435628	19	+	27260156	HT29	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.9708340453928788	[411]	[117,124,172,96]	-9	hSpCas9	negative selection	7329941
39433407	39433430	19	-	27260156	HT29	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.6340064751757444	[929]	[637,660,689,886]	-8	hSpCas9	negative selection	7329942
39433338	39433361	19	+	27260156	HT29	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.9153469122091026	[247]	[161,127,179,164]	-8	hSpCas9	negative selection	7329943
39435606	39435629	19	-	27260156	MHHES1	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.592826608616847	[1196]	[986,1135,908,622]	-8	hSpCas9	negative selection	7386939
39433664	39433687	19	-	27260156	MHHES1	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.4873604420710931	[385]	[518,887,677,404]	8	hSpCas9	negative selection	7386940
39433654	39433677	19	+	27260156	MHHES1	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.9639179510665459	[427]	[209,317,279,190]	-9	hSpCas9	negative selection	7386941
39435605	39435628	19	+	27260156	MHHES1	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-0.992185420314996	[411]	[253,160,324,192]	-9	hSpCas9	negative selection	7451192
39433407	39433430	19	-	27260156	MHHES1	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.18525209066123394	[929]	[1053,861,1114,696]	-4	hSpCas9	negative selection	7451193
39433338	39433361	19	+	27260156	MHHES1	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.9224786962628465	[247]	[190,118,93,176]	-9	hSpCas9	negative selection	7451194
39435606	39435629	19	-	27260156	MEWO	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.6387332414931146	[1196]	[703,857,591]	-8	hSpCas9	negative selection	7508190
39433664	39433687	19	-	27260156	MEWO	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.2912654455375989	[385]	[678,355,336]	6	hSpCas9	negative selection	7508191
39433654	39433677	19	+	27260156	MEWO	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.06987451728850624	[427]	[494,252,418]	-1	hSpCas9	negative selection	7508192
39435605	39435628	19	+	27260156	MEWO	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.6870263767687592	[411]	[124,144,89]	-9	hSpCas9	negative selection	7572443
39433407	39433430	19	-	27260156	MEWO	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.37975899206054353	[929]	[676,787,541]	-7	hSpCas9	negative selection	7572444
39433338	39433361	19	+	27260156	MEWO	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.5103781144320346	[247]	[159,175,151]	-8	hSpCas9	negative selection	7572445
39435606	39435629	19	-	27260156	LNCAPCLONEFGC	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.1548307178354347	[1196]	[397,536,533,483]	-9	hSpCas9	negative selection	7629441
39433664	39433687	19	-	27260156	LNCAPCLONEFGC	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.5616824064374701	[385]	[417,528,710,435]	8	hSpCas9	negative selection	7629442
39433654	39433677	19	+	27260156	LNCAPCLONEFGC	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.4883241212574933	[427]	[312,134,370,308]	-6	hSpCas9	negative selection	7629443
39435605	39435628	19	+	27260156	LNCAPCLONEFGC	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-2.417468872366228	[411]	[37,94,80,65]	-9	hSpCas9	negative selection	7693694
39433407	39433430	19	-	27260156	LNCAPCLONEFGC	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.473082408154303	[929]	[584,502,710,650]	-6	hSpCas9	negative selection	7693695
39433338	39433361	19	+	27260156	LNCAPCLONEFGC	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.6207508562942926	[247]	[154,135,160,134]	-7	hSpCas9	negative selection	7693696
39435606	39435629	19	-	27260156	PANC0327	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.8278648455802897	[1196]	[503,453,731,716]	-8	hSpCas9	negative selection	7750692
39433664	39433687	19	-	27260156	PANC0327	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.43698159157859834	[385]	[407,547,370,513]	6	hSpCas9	negative selection	7750693
39433654	39433677	19	+	27260156	PANC0327	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.10742450529138978	[427]	[248,239,581,346]	-2	hSpCas9	negative selection	7750694
39435605	39435628	19	+	27260156	PANC0327	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-2.9083969474991975	[411]	[28,89,28,39]	-9	hSpCas9	negative selection	7814945
39433407	39433430	19	-	27260156	PANC0327	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.803609511183806	[929]	[427,490,455,511]	-8	hSpCas9	negative selection	7814946
39433338	39433361	19	+	27260156	PANC0327	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-1.5865241041837885	[247]	[81,88,30,89]	-9	hSpCas9	negative selection	7814947
39435606	39435629	19	-	27260156	NCIH2009	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.63706848372615	[1196]	[611,363,653]	-9	hSpCas9	negative selection	7871943
39433664	39433687	19	-	27260156	NCIH2009	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.370447872654703	[385]	[887,646,593]	5	hSpCas9	negative selection	7871944
39433654	39433677	19	+	27260156	NCIH2009	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-1.1067197911296114	[427]	[294,220,320]	-8	hSpCas9	negative selection	7871945
39435605	39435628	19	+	27260156	NCIH2009	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.9292632708515165	[411]	[122,128,195]	-9	hSpCas9	negative selection	7936196
39433407	39433430	19	-	27260156	NCIH2009	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.6705831083002692	[929]	[1046,660,787]	-7	hSpCas9	negative selection	7936197
39433338	39433361	19	+	27260156	NCIH2009	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.8283915671885419	[247]	[194,141,248]	-7	hSpCas9	negative selection	7936198
39435606	39435629	19	-	27260156	NCIH1373	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.4236165616080372	[1196]	[490,391,686,112]	-8	hSpCas9	negative selection	7993194
39433664	39433687	19	-	27260156	NCIH1373	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	1.0012332790085456	[385]	[816,819,1093,186]	8	hSpCas9	negative selection	7993195
39433654	39433677	19	+	27260156	NCIH1373	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.696748055818643	[427]	[590,177,107,97]	-6	hSpCas9	negative selection	7993196
39435605	39435628	19	+	27260156	NCIH1373	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-2.0896749235112546	[411]	[185,57,26,48]	-9	hSpCas9	negative selection	8057447
39433407	39433430	19	-	27260156	NCIH1373	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.20197759676454208	[929]	[993,1225,551,217]	-2	hSpCas9	negative selection	8057448
39433338	39433361	19	+	27260156	NCIH1373	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.5692258677894929	[247]	[301,91,230,38]	-5	hSpCas9	negative selection	8057449
39435606	39435629	19	-	27260156	PATU8902	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.183753608352756	[1196]	[729,151,287,301]	-9	hSpCas9	negative selection	8114445
39433664	39433687	19	-	27260156	PATU8902	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	1.2811839684664668	[385]	[1493,1186,1212,1347]	9	hSpCas9	negative selection	8114446
39433654	39433677	19	+	27260156	PATU8902	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-2.9796618828114374	[427]	[27,92,13,197]	-9	hSpCas9	negative selection	8114447
39435605	39435628	19	+	27260156	PATU8902	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-3.1613134616060847	[411]	[65,11,141,8]	-9	hSpCas9	negative selection	8178698
39433407	39433430	19	-	27260156	PATU8902	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.5206150926526167	[929]	[405,1205,844,1205]	-5	hSpCas9	negative selection	8178699
39433338	39433361	19	+	27260156	PATU8902	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.2611883639397429	[247]	[438,284,238,185]	-3	hSpCas9	negative selection	8178700
39435606	39435629	19	-	27260156	PANC1	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.1243840115233774	[1196]	[235,358,187,188]	-9	hSpCas9	negative selection	8235696
39433664	39433687	19	-	27260156	PANC1	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.39246507685613535	[385]	[362,549,301,526]	6	hSpCas9	negative selection	8235697
39433654	39433677	19	+	27260156	PANC1	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-1.6601655706525738	[427]	[94,160,147,75]	-9	hSpCas9	negative selection	8235698
39435605	39435628	19	+	27260156	PANC1	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-2.0254451283401758	[411]	[102,46,141,51]	-9	hSpCas9	negative selection	8299949
39433407	39433430	19	-	27260156	PANC1	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-1.0864887791694362	[929]	[486,439,286,305]	-8	hSpCas9	negative selection	8299950
39433338	39433361	19	+	27260156	PANC1	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-1.0762639379120293	[247]	[84,139,73,109]	-8	hSpCas9	negative selection	8299951
39435606	39435629	19	-	27260156	PANC0813	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.068653044871699	[1196]	[482,742,502,918]	-8	hSpCas9	negative selection	8356947
39433664	39433687	19	-	27260156	PANC0813	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.49461227804748586	[385]	[572,639,808,532]	7	hSpCas9	negative selection	8356948
39433654	39433677	19	+	27260156	PANC0813	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.5082038035139653	[427]	[481,244,374,324]	-6	hSpCas9	negative selection	8356949
39435605	39435628	19	+	27260156	PANC0813	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.6627967673806896	[411]	[140,195,156,117]	-9	hSpCas9	negative selection	8421200
39433407	39433430	19	-	27260156	PANC0813	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.7499958913012559	[929]	[797,528,464,808]	-8	hSpCas9	negative selection	8421201
39433338	39433361	19	+	27260156	PANC0813	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.7938354406020364	[247]	[144,150,155,214]	-8	hSpCas9	negative selection	8421202
39435606	39435629	19	-	27260156	RDES	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.8809711271656253	[1196]	[575,732,906,804]	-9	hSpCas9	negative selection	8478198
39433664	39433687	19	-	27260156	RDES	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.5125171329469738	[385]	[581,631,551,775]	7	hSpCas9	negative selection	8478199
39433654	39433677	19	+	27260156	RDES	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.9290109059825893	[427]	[220,188,271,377]	-9	hSpCas9	negative selection	8478200
39435605	39435628	19	+	27260156	RDES	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.9016250684544285	[411]	[83,181,119,119]	-9	hSpCas9	negative selection	8542451
39433407	39433430	19	-	27260156	RDES	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.6017256916938588	[929]	[546,686,853,759]	-8	hSpCas9	negative selection	8542452
39433338	39433361	19	+	27260156	RDES	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.9867282199999677	[247]	[130,114,205,123]	-9	hSpCas9	negative selection	8542453
39435606	39435629	19	-	27260156	PC3	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.025203968490936868	[1196]	[778,1117,2080,1118]	0	hSpCas9	negative selection	8599449
39433664	39433687	19	-	27260156	PC3	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.2509155839385592	[385]	[237,552,638,526]	5	hSpCas9	negative selection	8599450
39433654	39433677	19	+	27260156	PC3	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	0.2000520857806686	[427]	[289,459,774,594]	4	hSpCas9	negative selection	8599451
39435605	39435628	19	+	27260156	PC3	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.3513017204206763	[411]	[141,267,101,84]	-9	hSpCas9	negative selection	8663702
39433407	39433430	19	-	27260156	PC3	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.3685725694582328	[929]	[430,682,1294,749]	-7	hSpCas9	negative selection	8663703
39433338	39433361	19	+	27260156	PC3	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.45614313086776426	[247]	[109,240,314,113]	-8	hSpCas9	negative selection	8663704
39435606	39435629	19	-	27260156	PATU8988T	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.1497526889347978	[1196]	[404,599,456,640]	-9	hSpCas9	negative selection	8720700
39433664	39433687	19	-	27260156	PATU8988T	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.5437852479873516	[385]	[504,586,522,565]	8	hSpCas9	negative selection	8720701
39433654	39433677	19	+	27260156	PATU8988T	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-1.2655006896510834	[427]	[84,139,173,295]	-9	hSpCas9	negative selection	8720702
39435605	39435628	19	+	27260156	PATU8988T	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-2.544045953775466	[411]	[27,65,82,97]	-9	hSpCas9	negative selection	8784953
39433407	39433430	19	-	27260156	PATU8988T	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.9291950764415761	[929]	[337,395,512,646]	-8	hSpCas9	negative selection	8784954
39433338	39433361	19	+	27260156	PATU8988T	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.8578635926701977	[247]	[100,191,87,155]	-8	hSpCas9	negative selection	8784955
39435606	39435629	19	-	27260156	T47D	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.2950190563652308	[1196]	[568,569,542,591]	-9	hSpCas9	negative selection	8841951
39433664	39433687	19	-	27260156	T47D	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.48484091415500874	[385]	[718,564,635,601]	8	hSpCas9	negative selection	8841952
39433654	39433677	19	+	27260156	T47D	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.3156338093313317	[427]	[372,297,538,398]	-6	hSpCas9	negative selection	8841953
39435605	39435628	19	+	27260156	T47D	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.9168646858955665	[411]	[159,132,141,70]	-9	hSpCas9	negative selection	8906204
39433407	39433430	19	-	27260156	T47D	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.5608225889188287	[929]	[717,748,720,748]	-8	hSpCas9	negative selection	8906205
39433338	39433361	19	+	27260156	T47D	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.5553902576681401	[247]	[146,197,187,254]	-8	hSpCas9	negative selection	8906206
39435606	39435629	19	-	27260156	SU8686	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.3644434006310968	[1196]	[459,439,442,506]	-9	hSpCas9	negative selection	8963202
39433664	39433687	19	-	27260156	SU8686	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.5053061204156404	[385]	[437,573,573,600]	8	hSpCas9	negative selection	8963203
39433654	39433677	19	+	27260156	SU8686	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.7208341788140848	[427]	[235,229,258,318]	-8	hSpCas9	negative selection	8963204
39435605	39435628	19	+	27260156	SU8686	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.6716611928000862	[411]	[124,124,139,121]	-9	hSpCas9	negative selection	9027455
39433407	39433430	19	-	27260156	SU8686	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.7407482157148846	[929]	[460,559,540,668]	-8	hSpCas9	negative selection	9027456
39433338	39433361	19	+	27260156	SU8686	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-1.5066033908636998	[247]	[111,55,108,66]	-9	hSpCas9	negative selection	9027457
39435606	39435629	19	-	27260156	SKES1	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.3485522566026349	[1196]	[1179,1055,762,807]	-6	hSpCas9	negative selection	9084453
39433664	39433687	19	-	27260156	SKES1	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.35239042980276836	[385]	[600,570,458,369]	7	hSpCas9	negative selection	9084454
39433654	39433677	19	+	27260156	SKES1	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.11292210730407137	[427]	[301,511,288,465]	-2	hSpCas9	negative selection	9084455
39435605	39435628	19	+	27260156	SKES1	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.2450760873592692	[411]	[220,217,125,142]	-9	hSpCas9	negative selection	9148706
39433407	39433430	19	-	27260156	SKES1	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.41551895236858627	[929]	[908,710,680,525]	-7	hSpCas9	negative selection	9148707
39433338	39433361	19	+	27260156	SKES1	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.44435235718345545	[247]	[272,224,150,103]	-7	hSpCas9	negative selection	9148708
39435606	39435629	19	-	27260156	TOV112D	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.1789013277956626	[1196]	[1213,1272,858,956]	-3	hSpCas9	negative selection	9205704
39433664	39433687	19	-	27260156	TOV112D	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.16047277663082993	[385]	[379,540,431,397]	3	hSpCas9	negative selection	9205705
39433654	39433677	19	+	27260156	TOV112D	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.12180531161852282	[427]	[484,667,237,262]	-2	hSpCas9	negative selection	9205706
39435605	39435628	19	+	27260156	TOV112D	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.1505547219688987	[411]	[225,224,220,86]	-9	hSpCas9	negative selection	9269957
39433407	39433430	19	-	27260156	TOV112D	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.3549853583715047	[929]	[726,821,626,757]	-6	hSpCas9	negative selection	9269958
39433338	39433361	19	+	27260156	TOV112D	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-1.1129174338360022	[247]	[134,129,98,100]	-9	hSpCas9	negative selection	9269959
39435606	39435629	19	-	27260156	TC71	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.29290402127127924	[1196]	[1023,973,939,1268]	-7	hSpCas9	negative selection	9326955
39433664	39433687	19	-	27260156	TC71	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.3844367224634636	[385]	[505,557,522,576]	8	hSpCas9	negative selection	9326956
39433654	39433677	19	+	27260156	TC71	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.46395731833872017	[427]	[336,312,345,333]	-8	hSpCas9	negative selection	9326957
39435605	39435628	19	+	27260156	TC71	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-0.9357625101533551	[411]	[109,269,237,312]	-9	hSpCas9	negative selection	9391208
39433407	39433430	19	-	27260156	TC71	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.24338607709412752	[929]	[672,886,838,981]	-6	hSpCas9	negative selection	9391209
39433338	39433361	19	+	27260156	TC71	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.3696607575171206	[247]	[276,159,191,191]	-7	hSpCas9	negative selection	9391210
39435606	39435629	19	-	27260156	TC32	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-0.7336494840193035	[1196]	[757,315,887,880]	-9	hSpCas9	negative selection	9448206
39433664	39433687	19	-	27260156	TC32	viability	GGTCACGTGGCCCAGATTTATGG	RPS16	ENSG00000105193	0.4932911771316658	[385]	[463,297,713,668]	8	hSpCas9	negative selection	9448207
39433654	39433677	19	+	27260156	TC32	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.4143245218433467	[427]	[244,152,459,431]	-6	hSpCas9	negative selection	9448208
39435605	39435628	19	+	27260156	TC32	viability	ACCTTGTACTGTAGCGTGCGCGG	RPS16	ENSG00000105193	-1.1435002329448065	[411]	[270,61,184,206]	-9	hSpCas9	negative selection	9512459
39433407	39433430	19	-	27260156	TC32	viability	CTTCTTGCCAGATGTGGATGAGG	RPS16	ENSG00000105193	-0.05821229787062987	[929]	[686,593,835,1331]	-1	hSpCas9	negative selection	9512460
39433338	39433361	19	+	27260156	TC32	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.5243048647316962	[247]	[156,124,139,230]	-7	hSpCas9	negative selection	9512461
39433639	39433662	19	-	27869803	HPAFII	viability after 27 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	-2.6105631402756346	[112]	[12,6,NaN]	-8	hSpCas9	negative selection	9567727
39433639	39433662	19	-	27869803	HPAFII	viability after 15 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	-1.1759366857871352	[112]	[62,47,NaN]	-8	hSpCas9	negative selection	9650176
39433639	39433662	19	-	27869803	ASPC1	viability after 36 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	-0.5563292915301609	[315]	[27,39,134]	-5	hSpCas9	negative selection	9732625
39433639	39433662	19	-	27869803	PATU8988S	viability after 35 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	-0.5598546201689056	[202]	[38,71,NaN]	-5	hSpCas9	negative selection	9815074
39433639	39433662	19	-	27869803	PATU8988S	viability after 31 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	-0.38008916603314824	[202]	[48,78,NaN]	-4	hSpCas9	negative selection	9897523
39433639	39433662	19	-	27869803	HPAFII	viability after 35 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	-5.838090409418513	[112]	[0,0,NaN]	-9	hSpCas9	negative selection	9979972
39433639	39433662	19	-	27869803	HPAFII	viability after 31 days	AGTCCCAGGAACTGGGCGCATGG	RPS16	ENSG00000105193	-2.8729167962119457	[112]	[0,16,NaN]	-8	hSpCas9	negative selection	10062421
39435690	39435713	19	-	28162770	P31FUJ	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-5.64219314055208	[254]	[5]	-9	hSpCas9	negative selection	10227857
39435621	39435644	19	+	28162770	P31FUJ	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-3.0561280833837663	[544]	[76]	-9	hSpCas9	negative selection	10227858
39433688	39433711	19	-	28162770	P31FUJ	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-1.9908294141084149	[114]	[33]	-8	hSpCas9	negative selection	10227859
39435862	39435885	19	-	28162770	P31FUJ	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	0.408116702280793	[58]	[91]	4	hSpCas9	negative selection	10227860
39435606	39435629	19	-	28162770	P31FUJ	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.475003106831007	[439]	[92]	-8	hSpCas9	negative selection	10227861
39433654	39433677	19	+	28162770	P31FUJ	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	0.21389222826714827	[754]	[1028]	2	hSpCas9	negative selection	10227862
39433282	39433305	19	+	28162770	P31FUJ	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-6.590354209032462	[81]	[0]	-9	hSpCas9	negative selection	10227863
39433338	39433361	19	+	28162770	P31FUJ	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-2.512225570787206	[300]	[61]	-8	hSpCas9	negative selection	10227864
39433323	39433346	19	+	28162770	P31FUJ	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.5710943978708143	[715]	[1249]	6	hSpCas9	negative selection	10227865
39435883	39435906	19	-	28162770	P31FUJ	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-2.9723417422444114	[186]	[27]	-9	hSpCas9	negative selection	10227866
39435690	39435713	19	-	28162770	TF1	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10397223
39435621	39435644	19	+	28162770	TF1	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10397224
39433688	39433711	19	-	28162770	TF1	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10397225
39435862	39435885	19	-	28162770	TF1	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10397226
39435606	39435629	19	-	28162770	TF1	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10397227
39433654	39433677	19	+	28162770	TF1	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	NaN	[NaN]	[549]	1	hSpCas9	negative selection	10397228
39433282	39433305	19	+	28162770	TF1	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10397229
39433338	39433361	19	+	28162770	TF1	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10397230
39433323	39433346	19	+	28162770	TF1	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	NaN	[NaN]	[792]	1	hSpCas9	negative selection	10397231
39435883	39435906	19	-	28162770	TF1	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10397232
39435690	39435713	19	-	28162770	SKM1	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-7.264945193870734	[86]	[0]	-9	hSpCas9	negative selection	10566589
39435621	39435644	19	+	28162770	SKM1	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-1.9453841135272876	[121]	[55]	-8	hSpCas9	negative selection	10566590
39433688	39433711	19	-	28162770	SKM1	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-2.652076696579693	[31]	[8]	-9	hSpCas9	negative selection	10566591
39435862	39435885	19	-	28162770	SKM1	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	-1.0064262691594332	[24]	[21]	-6	hSpCas9	negative selection	10566592
39435606	39435629	19	-	28162770	SKM1	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.5090623863618977	[160]	[49]	-9	hSpCas9	negative selection	10566593
39433654	39433677	19	+	28162770	SKM1	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.07810005664542308	[248]	[416]	0	hSpCas9	negative selection	10566594
39433282	39433305	19	+	28162770	SKM1	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-4.6293566200796095	[13]	[0]	-9	hSpCas9	negative selection	10566595
39433338	39433361	19	+	28162770	SKM1	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-1.2814333166593028	[65]	[47]	-7	hSpCas9	negative selection	10566596
39433323	39433346	19	+	28162770	SKM1	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.4999263968653569	[135]	[339]	5	hSpCas9	negative selection	10566597
39435883	39435906	19	-	28162770	SKM1	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-4.663303952002948	[42]	[2]	-9	hSpCas9	negative selection	10566598
39435690	39435713	19	-	28162770	SKM1	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-7.264945193870734	[86]	[0]	-9	hSpCas9	negative selection	10735955
39435621	39435644	19	+	28162770	SKM1	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-1.9453841135272876	[121]	[55]	-8	hSpCas9	negative selection	10735956
39433688	39433711	19	-	28162770	SKM1	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-2.652076696579693	[31]	[8]	-9	hSpCas9	negative selection	10735957
39435862	39435885	19	-	28162770	SKM1	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	-1.0064262691594332	[24]	[21]	-6	hSpCas9	negative selection	10735958
39435606	39435629	19	-	28162770	SKM1	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.5090623863618977	[160]	[49]	-9	hSpCas9	negative selection	10735959
39433654	39433677	19	+	28162770	SKM1	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.07810005664542308	[248]	[416]	0	hSpCas9	negative selection	10735960
39433282	39433305	19	+	28162770	SKM1	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-4.6293566200796095	[13]	[0]	-9	hSpCas9	negative selection	10735961
39433338	39433361	19	+	28162770	SKM1	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-1.2814333166593028	[65]	[47]	-7	hSpCas9	negative selection	10735962
39433323	39433346	19	+	28162770	SKM1	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.4999263968653569	[135]	[339]	5	hSpCas9	negative selection	10735963
39435883	39435906	19	-	28162770	SKM1	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-4.663303952002948	[42]	[2]	-9	hSpCas9	negative selection	10735964
39435690	39435713	19	-	28162770	PL21	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-3.7384598408465366	[275]	[8]	-9	hSpCas9	negative selection	10905321
39435621	39435644	19	+	28162770	PL21	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-1.1797084563272235	[431]	[82]	-7	hSpCas9	negative selection	10905322
39433688	39433711	19	-	28162770	PL21	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-1.0477878989542657	[151]	[31]	-6	hSpCas9	negative selection	10905323
39435862	39435885	19	-	28162770	PL21	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	-2.1456352223524098	[60]	[5]	-8	hSpCas9	negative selection	10905324
39435606	39435629	19	-	28162770	PL21	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.213938327028251	[500]	[46]	-8	hSpCas9	negative selection	10905325
39433654	39433677	19	+	28162770	PL21	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	0.3035573741696054	[766]	[411]	2	hSpCas9	negative selection	10905326
39433282	39433305	19	+	28162770	PL21	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-1.6649308054245713	[50]	[6]	-8	hSpCas9	negative selection	10905327
39433338	39433361	19	+	28162770	PL21	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-0.39404141626121464	[156]	[51]	-3	hSpCas9	negative selection	10905328
39433323	39433346	19	+	28162770	PL21	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.007890066375553673	[520]	[227]	0	hSpCas9	negative selection	10905329
39435883	39435906	19	-	28162770	PL21	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-5.028679076006561	[149]	[1]	-9	hSpCas9	negative selection	10905330
39435690	39435713	19	-	28162770	P31FUJ	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-5.64219314055208	[254]	[5]	-9	hSpCas9	negative selection	11074687
39435621	39435644	19	+	28162770	P31FUJ	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-3.0561280833837663	[544]	[76]	-9	hSpCas9	negative selection	11074688
39433688	39433711	19	-	28162770	P31FUJ	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-1.9908294141084149	[114]	[33]	-8	hSpCas9	negative selection	11074689
39435862	39435885	19	-	28162770	P31FUJ	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	0.408116702280793	[58]	[91]	4	hSpCas9	negative selection	11074690
39435606	39435629	19	-	28162770	P31FUJ	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.475003106831007	[439]	[92]	-8	hSpCas9	negative selection	11074691
39433654	39433677	19	+	28162770	P31FUJ	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	0.21389222826714827	[754]	[1028]	2	hSpCas9	negative selection	11074692
39433282	39433305	19	+	28162770	P31FUJ	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-6.590354209032462	[81]	[0]	-9	hSpCas9	negative selection	11074693
39433338	39433361	19	+	28162770	P31FUJ	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-2.512225570787206	[300]	[61]	-8	hSpCas9	negative selection	11074694
39433323	39433346	19	+	28162770	P31FUJ	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.5710943978708143	[715]	[1249]	6	hSpCas9	negative selection	11074695
39435883	39435906	19	-	28162770	P31FUJ	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-2.9723417422444114	[186]	[27]	-9	hSpCas9	negative selection	11074696
39435690	39435713	19	-	28162770	OCIAML5	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-4.793514388508884	[168]	[10]	-9	hSpCas9	negative selection	11244053
39435621	39435644	19	+	28162770	OCIAML5	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-4.2727286193367195	[256]	[23]	-9	hSpCas9	negative selection	11244054
39433688	39433711	19	-	28162770	OCIAML5	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-5.456928629022858	[72]	[2]	-9	hSpCas9	negative selection	11244055
39435862	39435885	19	-	28162770	OCIAML5	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	-1.0537004320336476	[22]	[19]	-6	hSpCas9	negative selection	11244056
39435606	39435629	19	-	28162770	OCIAML5	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-3.1403115394950705	[253]	[51]	-9	hSpCas9	negative selection	11244057
39433654	39433677	19	+	28162770	OCIAML5	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.7580904226549832	[415]	[443]	-5	hSpCas9	negative selection	11244058
39433282	39433305	19	+	28162770	OCIAML5	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-5.244383993642757	[20]	[0]	-9	hSpCas9	negative selection	11244059
39433338	39433361	19	+	28162770	OCIAML5	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-6.386045142866348	[138]	[2]	-9	hSpCas9	negative selection	11244060
39433323	39433346	19	+	28162770	OCIAML5	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	-0.21202354495019393	[393]	[613]	-1	hSpCas9	negative selection	11244061
39435883	39435906	19	-	28162770	OCIAML5	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-7.939529412114337	[135]	[0]	-9	hSpCas9	negative selection	11244062
39435690	39435713	19	-	28162770	EOL1	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-2.8554307115557642	[521]	[37]	-9	hSpCas9	negative selection	11413419
39435621	39435644	19	+	28162770	EOL1	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-4.366534356364069	[508]	[12]	-9	hSpCas9	negative selection	11413420
39433688	39433711	19	-	28162770	EOL1	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-5.473483302402619	[252]	[2]	-9	hSpCas9	negative selection	11413421
39435862	39435885	19	-	28162770	EOL1	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	-2.30574984785126	[121]	[12]	-8	hSpCas9	negative selection	11413422
39435606	39435629	19	-	28162770	EOL1	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-3.4065597500912235	[945]	[46]	-9	hSpCas9	negative selection	11413423
39433654	39433677	19	+	28162770	EOL1	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.06691554647497977	[1347]	[677]	0	hSpCas9	negative selection	11413424
39433282	39433305	19	+	28162770	EOL1	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-4.982342824037984	[59]	[0]	-9	hSpCas9	negative selection	11413425
39433338	39433361	19	+	28162770	EOL1	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-2.8530598070930178	[287]	[20]	-9	hSpCas9	negative selection	11413426
39433323	39433346	19	+	28162770	EOL1	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.04417663226093804	[693]	[376]	0	hSpCas9	negative selection	11413427
39435883	39435906	19	-	28162770	EOL1	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-6.599014184486478	[183]	[0]	-9	hSpCas9	negative selection	11413428
39435690	39435713	19	-	28162770	MOLM13	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-2.922210215984363	[324]	[30]	-8	hSpCas9	negative selection	11582785
39435621	39435644	19	+	28162770	MOLM13	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-5.653644135795453	[556]	[7]	-9	hSpCas9	negative selection	11582786
39433688	39433711	19	-	28162770	MOLM13	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-3.068163518695631	[173]	[14]	-8	hSpCas9	negative selection	11582787
39435862	39435885	19	-	28162770	MOLM13	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	0.1403147235160742	[63]	[50]	1	hSpCas9	negative selection	11582788
39435606	39435629	19	-	28162770	MOLM13	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-4.184955591457401	[804]	[31]	-9	hSpCas9	negative selection	11582789
39433654	39433677	19	+	28162770	MOLM13	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.6098232871526779	[1105]	[523]	-4	hSpCas9	negative selection	11582790
39433282	39433305	19	+	28162770	MOLM13	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-4.854038713342784	[79]	[1]	-9	hSpCas9	negative selection	11582791
39433338	39433361	19	+	28162770	MOLM13	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-7.858540105577725	[320]	[0]	-9	hSpCas9	negative selection	11582792
39433323	39433346	19	+	28162770	MOLM13	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	-1.7922990700659878	[708]	[147]	-7	hSpCas9	negative selection	11582793
39435883	39435906	19	-	28162770	MOLM13	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-7.0556725745124345	[183]	[0]	-9	hSpCas9	negative selection	11582794
39435690	39435713	19	-	28162770	HEL	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-4.758140604281827	[337]	[7]	-9	hSpCas9	negative selection	11752151
39435621	39435644	19	+	28162770	HEL	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-3.666589226107372	[455]	[22]	-9	hSpCas9	negative selection	11752152
39433688	39433711	19	-	28162770	HEL	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-5.138620881524303	[219]	[3]	-9	hSpCas9	negative selection	11752153
39435862	39435885	19	-	28162770	HEL	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	-0.47827656896100934	[86]	[39]	-3	hSpCas9	negative selection	11752154
39435606	39435629	19	-	28162770	HEL	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.1760914093897081	[567]	[160]	-6	hSpCas9	negative selection	11752155
39433654	39433677	19	+	28162770	HEL	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	1.014256616181176	[1017]	[1316]	8	hSpCas9	negative selection	11752156
39433282	39433305	19	+	28162770	HEL	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-4.880823124056656	[45]	[0]	-9	hSpCas9	negative selection	11752157
39433338	39433361	19	+	28162770	HEL	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-4.311457478386519	[340]	[10]	-9	hSpCas9	negative selection	11752158
39433323	39433346	19	+	28162770	HEL	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	-0.06991330482242519	[607]	[370]	0	hSpCas9	negative selection	11752159
39435883	39435906	19	-	28162770	HEL	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-1.487657805255318	[161]	[36]	-7	hSpCas9	negative selection	11752160
39435690	39435713	19	-	28162770	MV411	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-3.806639121973017	[298]	[17]	-9	hSpCas9	negative selection	11921517
39435621	39435644	19	+	28162770	MV411	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-2.752562449217225	[319]	[39]	-9	hSpCas9	negative selection	11921518
39433688	39433711	19	-	28162770	MV411	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-2.3848306647167377	[123]	[19]	-8	hSpCas9	negative selection	11921519
39435862	39435885	19	-	28162770	MV411	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	-2.3639971612995723	[54]	[8]	-8	hSpCas9	negative selection	11921520
39435606	39435629	19	-	28162770	MV411	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.986052579437003	[347]	[36]	-9	hSpCas9	negative selection	11921521
39433654	39433677	19	+	28162770	MV411	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	0.35124713452483114	[763]	[820]	3	hSpCas9	negative selection	11921522
39433282	39433305	19	+	28162770	MV411	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-5.39641863899195	[49]	[0]	-9	hSpCas9	negative selection	11921523
39433338	39433361	19	+	28162770	MV411	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-2.8363308069098228	[194]	[22]	-9	hSpCas9	negative selection	11921524
39433323	39433346	19	+	28162770	MV411	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.6819712256874164	[440]	[595]	6	hSpCas9	negative selection	11921525
39435883	39435906	19	-	28162770	MV411	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-1.565793937611498	[122]	[34]	-7	hSpCas9	negative selection	11921526
39435690	39435713	19	-	28162770	MONOMAC1	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-3.31251406447949	[181]	[20]	-9	hSpCas9	negative selection	12090883
39435621	39435644	19	+	28162770	MONOMAC1	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-1.9173512006755957	[200]	[60]	-8	hSpCas9	negative selection	12090884
39433688	39433711	19	-	28162770	MONOMAC1	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-0.8751087521721914	[95]	[59]	-6	hSpCas9	negative selection	12090885
39435862	39435885	19	-	28162770	MONOMAC1	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	0.03562390973072116	[39]	[46]	0	hSpCas9	negative selection	12090886
39435606	39435629	19	-	28162770	MONOMAC1	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-1.7745818762182268	[387]	[129]	-8	hSpCas9	negative selection	12090887
39433654	39433677	19	+	28162770	MONOMAC1	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.23876397266927696	[455]	[442]	-2	hSpCas9	negative selection	12090888
39433282	39433305	19	+	28162770	MONOMAC1	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-3.2844996883098934	[50]	[5]	-9	hSpCas9	negative selection	12090889
39433338	39433361	19	+	28162770	MONOMAC1	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-2.0335381147766745	[124]	[34]	-8	hSpCas9	negative selection	12090890
39433323	39433346	19	+	28162770	MONOMAC1	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.03428869904690224	[321]	[377]	0	hSpCas9	negative selection	12090891
39435883	39435906	19	-	28162770	MONOMAC1	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-2.7330897472997635	[86]	[14]	-9	hSpCas9	negative selection	12090892
39435690	39435713	19	-	28162770	OCIAML2	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-7.896894579944259	[42]	[0]	-9	hSpCas9	negative selection	12260249
39435621	39435644	19	+	28162770	OCIAML2	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-2.9300614438794583	[65]	[47]	-9	hSpCas9	negative selection	12260250
39433688	39433711	19	-	28162770	OCIAML2	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-4.027023173766547	[49]	[16]	-9	hSpCas9	negative selection	12260251
39435862	39435885	19	-	28162770	OCIAML2	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	0.43626077036635746	[9]	[74]	4	hSpCas9	negative selection	12260252
39435606	39435629	19	-	28162770	OCIAML2	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-3.0044534769715163	[96]	[66]	-9	hSpCas9	negative selection	12260253
39433654	39433677	19	+	28162770	OCIAML2	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.8231090115250144	[172]	[541]	-5	hSpCas9	negative selection	12260254
39433282	39433305	19	+	28162770	OCIAML2	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-6.0555923259633175	[11]	[0]	-9	hSpCas9	negative selection	12260255
39433338	39433361	19	+	28162770	OCIAML2	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-2.9345769250019513	[39]	[28]	-9	hSpCas9	negative selection	12260256
39433323	39433346	19	+	28162770	OCIAML2	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.49005725073301276	[92]	[723]	5	hSpCas9	negative selection	12260257
39435883	39435906	19	-	28162770	OCIAML2	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-3.3775204208506797	[14]	[7]	-9	hSpCas9	negative selection	12260258
39435690	39435713	19	-	28162770	OCIAML3	viability	ACAGAAGACAGCGACAGCTGTGG	RPS16	ENSG00000105193	-4.822826330820044	[74]	[7]	-9	hSpCas9	negative selection	12429615
39435621	39435644	19	+	28162770	OCIAML3	viability	TGCGCGGCTCAATCATCTCCAGG	RPS16	ENSG00000105193	-2.633536004510801	[110]	[53]	-9	hSpCas9	negative selection	12429616
39433688	39433711	19	-	28162770	OCIAML3	viability	ATCCGTGTCCGTGTAAAGGGTGG	RPS16	ENSG00000105193	-1.1868322588182898	[45]	[60]	-7	hSpCas9	negative selection	12429617
39435862	39435885	19	-	28162770	OCIAML3	viability	GGGCCCGCTGCAGTCTGTGCAGG	RPS16	ENSG00000105193	-1.079434467494405	[13]	[19]	-6	hSpCas9	negative selection	12429618
39435606	39435629	19	-	28162770	OCIAML3	viability	GCCGCGCACGCTACAGTACAAGG	RPS16	ENSG00000105193	-2.560840776388964	[128]	[65]	-9	hSpCas9	negative selection	12429619
39433654	39433677	19	+	28162770	OCIAML3	viability	CTGGGACTCACCATAAATCTGGG	RPS16	ENSG00000105193	-0.1264410899043671	[208]	[577]	-1	hSpCas9	negative selection	12429620
39433282	39433305	19	+	28162770	OCIAML3	viability	GGATTTCTGGTAGCGAGCGCGGG	RPS16	ENSG00000105193	-4.294447358465256	[12]	[1]	-9	hSpCas9	negative selection	12429621
39433338	39433361	19	+	28162770	OCIAML3	viability	GACGAGGGTCAGCTACCAGCAGG	RPS16	ENSG00000105193	-1.5099433755356888	[49]	[52]	-8	hSpCas9	negative selection	12429622
39433323	39433346	19	+	28162770	OCIAML3	viability	TTTTGGACTCGCAGCGACGAGGG	RPS16	ENSG00000105193	0.3478894051122685	[151]	[583]	3	hSpCas9	negative selection	12429623
39435883	39435906	19	-	28162770	OCIAML3	viability	GCTCGGAGCCATGCCGTCCAAGG	RPS16	ENSG00000105193	-2.738397549659338	[41]	[18]	-9	hSpCas9	negative selection	12429624