Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 117157
• Symbol: SH2D1B
• Description: SH2 domain containing 1B

DataSource: http://genomecrispr.dkfz.de/#!/results/SH2D1B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
162411944	162411967	1	-	26472758	Jiyoye	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	-1.111291707428376	[105]	[36]	-6	hSpCas9	negative selection	146025
162398947	162398970	1	+	26472758	Jiyoye	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	0.5654374654226059	[137]	[153]	4	hSpCas9	negative selection	146026
162402754	162402777	1	-	26472758	Jiyoye	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	0.6828098241193008	[37]	[45]	5	hSpCas9	negative selection	146027
162411872	162411895	1	+	26472758	Jiyoye	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	4.992137882227029	[0]	[23]	9	hSpCas9	negative selection	146028
162411996	162412019	1	+	26472758	Jiyoye	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	-0.08017632258886051	[149]	[106]	0	hSpCas9	negative selection	146029
162399003	162399026	1	-	26472758	Jiyoye	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	1.8290020464473564	[52]	[141]	8	hSpCas9	negative selection	146030
162399035	162399058	1	+	26472758	Jiyoye	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	-0.7729453870423275	[425]	[187]	-5	hSpCas9	negative selection	146031
162399045	162399068	1	-	26472758	Jiyoye	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	2.1661672820020783	[12]	[43]	9	hSpCas9	negative selection	146032
162411977	162412000	1	+	26472758	Jiyoye	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.18946892426291817	[185]	[122]	-1	hSpCas9	negative selection	146033
162397294	162397317	1	-	26472758	Jiyoye	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	0.29321919220878756	[78]	[72]	2	hSpCas9	negative selection	146034
162411944	162411967	1	-	26472758	KBM7	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	0.7846314183193476	[150,166]	[156,105]	8	hSpCas9	negative selection	337143
162398947	162398970	1	+	26472758	KBM7	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	0.1082883809142331	[898,731]	[391,427]	1	hSpCas9	negative selection	337144
162402754	162402777	1	-	26472758	KBM7	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	-0.08735637573683841	[299,297]	[190,80]	-1	hSpCas9	negative selection	337145
162411872	162411895	1	+	26472758	KBM7	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.5320941973848743	[62,138]	[49,90]	6	hSpCas9	negative selection	337146
162411996	162412019	1	+	26472758	KBM7	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.22795738000443574	[568,517]	[368,236]	2	hSpCas9	negative selection	337147
162399003	162399026	1	-	26472758	KBM7	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	0.4642540974059135	[636,585]	[445,352]	5	hSpCas9	negative selection	337148
162399035	162399058	1	+	26472758	KBM7	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.10965233837137478	[1162,1137]	[597,574]	1	hSpCas9	negative selection	337149
162399045	162399068	1	-	26472758	KBM7	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.4425165832593716	[228,201]	[99,170]	5	hSpCas9	negative selection	337150
162411977	162412000	1	+	26472758	KBM7	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.9139987087785364	[567,492]	[555,390]	8	hSpCas9	negative selection	337151
162397294	162397317	1	-	26472758	KBM7	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	0.854936129036829	[351,521]	[383,377]	8	hSpCas9	negative selection	337152
162411944	162411967	1	-	26472758	Raji	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	0.9585201494591167	[50]	[22]	8	hSpCas9	negative selection	528261
162398947	162398970	1	+	26472758	Raji	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	-0.17431471472522997	[388]	[79]	-1	hSpCas9	negative selection	528262
162402754	162402777	1	-	26472758	Raji	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	0.4205414206332299	[131]	[40]	4	hSpCas9	negative selection	528263
162411872	162411895	1	+	26472758	Raji	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	1.7288719121198697	[25]	[19]	9	hSpCas9	negative selection	528264
162411996	162412019	1	+	26472758	Raji	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.27003387301815807	[242]	[67]	2	hSpCas9	negative selection	528265
162399003	162399026	1	-	26472758	Raji	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	0.3340760941436728	[334]	[97]	3	hSpCas9	negative selection	528266
162399035	162399058	1	+	26472758	Raji	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	-0.20340400190856245	[515]	[103]	-2	hSpCas9	negative selection	528267
162399045	162399068	1	-	26472758	Raji	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	1.5224210346524432	[74]	[49]	9	hSpCas9	negative selection	528268
162411977	162412000	1	+	26472758	Raji	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.23636997609367744	[277]	[75]	2	hSpCas9	negative selection	528269
162397294	162397317	1	-	26472758	Raji	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	0.11966186515203621	[233]	[58]	1	hSpCas9	negative selection	528270
162411944	162411967	1	-	26472758	K562	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	0.13604256662165493	[151]	[140]	1	hSpCas9	negative selection	719379
162398947	162398970	1	+	26472758	K562	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	0.03452017411771213	[708]	[612]	0	hSpCas9	negative selection	719380
162402754	162402777	1	-	26472758	K562	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	0.1813086838118086	[256]	[245]	1	hSpCas9	negative selection	719381
162411872	162411895	1	+	26472758	K562	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.20069735023712898	[66]	[64]	1	hSpCas9	negative selection	719382
162411996	162412019	1	+	26472758	K562	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	1.088097947567911	[408]	[733]	8	hSpCas9	negative selection	719383
162399003	162399026	1	-	26472758	K562	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	0.39012458265028715	[573]	[634]	3	hSpCas9	negative selection	719384
162399035	162399058	1	+	26472758	K562	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.8993094103454312	[744]	[1172]	7	hSpCas9	negative selection	719385
162399045	162399068	1	-	26472758	K562	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	-0.2731885052529446	[135]	[94]	-2	hSpCas9	negative selection	719386
162411977	162412000	1	+	26472758	K562	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.6221919588333137	[450]	[585]	5	hSpCas9	negative selection	719387
162397294	162397317	1	-	26472758	K562	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	1.7440491745878406	[295]	[836]	9	hSpCas9	negative selection	719388
162411872	162411895	1	+	26627737	DLD1	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	1.085012277814189	[478]	[249,451,264]	8	hSpCas9	negative selection	767196
162411872	162411895	1	+	26627737	GBM cells	viability after 5 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.5886630824702688	[322]	[254,265]	8	hSpCas9	negative selection	849511
162411872	162411895	1	+	26627737	GBM cells	viability after 13 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.1864790669910414	[322]	[242,163]	2	hSpCas9	negative selection	931826
162411872	162411895	1	+	26627737	GBM cells	viability after 21 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.19621360471590982	[322]	[199,201]	2	hSpCas9	negative selection	1014141
162411872	162411895	1	+	26627737	RPE1	viability after 9 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	2.834562664642619	[216]	[412,576]	9	hSpCas9	negative selection	1096456
162411872	162411895	1	+	26627737	RPE1	viability after 12 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	3.1417877230773303	[216]	[448,583]	9	hSpCas9	negative selection	1178771
162411872	162411895	1	+	26627737	RPE1	viability after 15 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	3.026849893177351	[216]	[398,597]	9	hSpCas9	negative selection	1261086
162411872	162411895	1	+	26627737	RPE1	viability after 18 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	3.4203296066197044	[216]	[508,752]	9	hSpCas9	negative selection	1343401
162411872	162411895	1	+	26627737	HeLa	viability after 8 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.4711214610360095	[695]	[328,120,228]	-4	hSpCas9	negative selection	1425716
162411872	162411895	1	+	26627737	HeLa	viability after 12 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.15677476344326502	[695]	[287,348,320]	1	hSpCas9	negative selection	1508031
162411872	162411895	1	+	26627737	HeLa	viability after 15 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.6063115844938491	[695]	[229,102,227]	-5	hSpCas9	negative selection	1590346
162411872	162411895	1	+	26627737	HeLa	viability after 18 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.5714760812893576	[695]	[164,82,227]	-5	hSpCas9	negative selection	1672661
162411872	162411895	1	+	26627737	HCT116	viability after 6 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.18840040532097246	[1573]	[104,278]	-1	hSpCas9	negative selection	1754976
162411872	162411895	1	+	26627737	HCT116	viability after 8 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.7144167545103512	[251]	[203,242,235]	6	hSpCas9	negative selection	1837291
162411872	162411895	1	+	26627737	HCT116	viability after 9 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-1.3795580127483866	[1573]	[289,59]	-7	hSpCas9	negative selection	1919606
162411872	162411895	1	+	26627737	HCT116	viability after 12 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.9274097601805044	[251]	[203,300,255]	7	hSpCas9	negative selection	2001921
162411872	162411895	1	+	26627737	HCT116	viability after 15 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	1.1927916243190848	[251]	[381,309,306]	8	hSpCas9	negative selection	2084236
162411872	162411895	1	+	26627737	HCT116	viability after 18 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	1.1252425214524995	[251]	[267,309,213]	8	hSpCas9	negative selection	2166551
162408963	162408986	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGCGCACTACCATGCCTGG	SH2D1B	ENSG00000198574	-0.15715732429472484	[256,379]	[34,91]	0	dCas9-VP64	positive selection	2394965
162408454	162408477	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCACCACTGCACTCCAGCCGGG	SH2D1B	ENSG00000198574	3.0347564003538725	[8,6]	[27,0]	8	dCas9-VP64	positive selection	2470792
162408963	162408986	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGCGCACTACCATGCCTGG	SH2D1B	ENSG00000198574	1.0509624744375528	[149,94]	[37,125]	6	dCas9-VP64	positive selection	2490220
162408454	162408477	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCACCACTGCACTCCAGCCGGG	SH2D1B	ENSG00000198574	0.038175304513698105	[60,77]	[26,18]	0	dCas9-VP64	positive selection	2566047
162411873	162411896	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.11919731455809845	[3,3]	[3,1]	-2	hSpCas9	positive selection	3019987
162411997	162412020	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	-0.2279774060982741	[5,4]	[5,1]	-3	hSpCas9	positive selection	3019988
162402755	162402778	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.3865076901412245	[3,3]	[3,0]	-5	hSpCas9	positive selection	3019989
162402754	162402777	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	0.11202197233636495	[3,3]	[3,3]	2	hSpCas9	positive selection	3019990
162411873	162411896	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.31800516216254937	[3,3]	[3,0]	-5	hSpCas9	positive selection	3087845
162411997	162412020	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	-0.1310068833190952	[5,5]	[2,3]	-2	hSpCas9	positive selection	3087846
162402755	162402778	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	0.1979552349020366	[3,3]	[2,2]	3	hSpCas9	positive selection	3087847
162402754	162402777	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	0.469008814859038	[3,3]	[3,3]	7	hSpCas9	positive selection	3087848
162399045	162399068		-	24336571	A375	resistance to PLX after 7 days	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.022973885631673907	[3,3]	[3,3]	0	hSpCas9	positive selection	3143901
162402755	162402778		-	24336571	A375	resistance to PLX after 7 days	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.2760651880632967	[7,5]	[5,4]	-7	hSpCas9	positive selection	3143902
162402756	162402779		+	24336571	A375	resistance to PLX after 7 days	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.10470176174297297	[6,8]	[7,8]	3	hSpCas9	positive selection	3143903
162399077	162399100		-	24336571	A375	resistance to PLX after 7 days	GTATTTTTGCAGACTGCAGAAGG	SH2D1B	ENSG00000198574	-0.2102345758358639	[3,4]	[3,2]	-6	hSpCas9	positive selection	3143904
162398999	162399022		+	24336571	A375	resistance to PLX after 7 days	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	-0.12972467554979095	[32,35]	[30,31]	-4	hSpCas9	positive selection	3143905
162399045	162399068		-	24336571	A375	resistance to PLX after 14 days	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	-0.1408436207092989	[5,4]	[1,1]	-1	hSpCas9	positive selection	3201694
162402755	162402778		-	24336571	A375	resistance to PLX after 14 days	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.09270732886274846	[6,3]	[1,1]	-1	hSpCas9	positive selection	3201695
162402756	162402779		+	24336571	A375	resistance to PLX after 14 days	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.8523224664297816	[6,4]	[5,3]	7	hSpCas9	positive selection	3201696
162399077	162399100		-	24336571	A375	resistance to PLX after 14 days	GTATTTTTGCAGACTGCAGAAGG	SH2D1B	ENSG00000198574	1.388782537931449	[3,2]	[2,5]	8	hSpCas9	positive selection	3201697
162398999	162399022		+	24336571	A375	resistance to PLX after 14 days	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.35470640869718806	[21,43]	[17,20]	3	hSpCas9	positive selection	3201698
162399045	162399068		-	24336571	A375	viability after 7 days	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	-0.3475235797389602	[4]	[3,3]	-5	hSpCas9	negative selection	3259487
162402755	162402778		-	24336571	A375	viability after 7 days	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.3007159431204275	[8]	[7,5]	-4	hSpCas9	negative selection	3259488
162402756	162402779		+	24336571	A375	viability after 7 days	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.9105691980081957	[3]	[6,8]	9	hSpCas9	negative selection	3259489
162399077	162399100		-	24336571	A375	viability after 7 days	GTATTTTTGCAGACTGCAGAAGG	SH2D1B	ENSG00000198574	-0.2629080392670937	[5]	[3,4]	-4	hSpCas9	negative selection	3259490
162398999	162399022		+	24336571	A375	viability after 7 days	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.5086535158757217	[24]	[32,35]	7	hSpCas9	negative selection	3259491
162399045	162399068		-	24336571	A375	viability after 14 days	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.16953964162942214	[4]	[5,4]	2	hSpCas9	negative selection	3317280
162402755	162402778		-	24336571	A375	viability after 14 days	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.5604675846294686	[8]	[6,3]	-6	hSpCas9	negative selection	3317281
162402756	162402779		+	24336571	A375	viability after 14 days	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.5843855514805494	[3]	[6,4]	7	hSpCas9	negative selection	3317282
162399077	162399100		-	24336571	A375	viability after 14 days	GTATTTTTGCAGACTGCAGAAGG	SH2D1B	ENSG00000198574	-0.4510701315821153	[5]	[3,2]	-5	hSpCas9	negative selection	3317283
162398999	162399022		+	24336571	A375	viability after 14 days	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.46643547445954936	[24]	[21,43]	6	hSpCas9	negative selection	3317284
162398999	162399022	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	2.4499712893882304	[251,251]	[8,8]	8	hSpCas9	positive selection	3392198
162402756	162402779	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	1.8650087886670745	[41,41]	[0,0]	7	hSpCas9	positive selection	3392199
162399063	162399086	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	-0.0735906666687818	[160,160]	[0,0]	0	hSpCas9	positive selection	3392200
162411872	162411895	1	+	26780180	HT29	viability (Avana library 4 designs)	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.209217177577608	[]	[]	-3	hSpCas9	negative selection	3458491
162411996	162412019	1	+	26780180	HT29	viability (Avana library 4 designs)	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.529680463167065	[]	[]	2	hSpCas9	negative selection	3458492
162402755	162402778	1	-	26780180	HT29	viability (Avana library 4 designs)	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	2.13242493062406	[]	[]	7	hSpCas9	negative selection	3458493
162402754	162402777	1	-	26780180	HT29	viability (Avana library 4 designs)	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	0.908517655466673	[]	[]	3	hSpCas9	negative selection	3458494
162411872	162411895	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-1.8214942231366	[]	[]	-2	hSpCas9	negative selection	3557958
162402754	162402777	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	-11.0702970023216	[]	[]	-8	hSpCas9	negative selection	3557959
162402755	162402778	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-7.91352016243607	[]	[]	-7	hSpCas9	negative selection	3557960
162411996	162412019	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	2.56966476130901	[]	[]	4	hSpCas9	negative selection	3557961
162411904	162411927	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.636439815816592	[]	[]	0	hSpCas9	negative selection	3557962
162411948	162411971	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGACCTTGCTGCTCAAGGAAGGG	SH2D1B	ENSG00000198574	1.51317048867009	[]	[]	2	hSpCas9	negative selection	3557963
162411872	162411895	1	+	26780180	A375	viability (Avana lentiGuide)	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.023031881630339	[]	[]	0	hSpCas9	negative selection	3666617
162402754	162402777	1	-	26780180	A375	viability (Avana lentiGuide)	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	6.14037215785949	[]	[]	5	hSpCas9	negative selection	3666618
162402755	162402778	1	-	26780180	A375	viability (Avana lentiGuide)	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.937970604521638	[]	[]	-1	hSpCas9	negative selection	3666619
162411996	162412019	1	+	26780180	A375	viability (Avana lentiGuide)	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	-2.5620125275139	[]	[]	-4	hSpCas9	negative selection	3666620
162411904	162411927	1	-	26780180	A375	viability (Avana lentiGuide)	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	1.31407405661031	[]	[]	1	hSpCas9	negative selection	3666621
162411948	162411971	1	-	26780180	A375	viability (Avana lentiGuide)	AGACCTTGCTGCTCAAGGAAGGG	SH2D1B	ENSG00000198574	6.48088765887903	[]	[]	5	hSpCas9	negative selection	3666622
162411872	162411895	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.7229825726268075	[4]	[2,1]	-8	hSpCas9	positive selection	3775224
162402754	162402777	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	-1.1984466282037782	[5]	[2,1]	-9	hSpCas9	positive selection	3775225
162402755	162402778	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.27837850894898836	[5]	[4,3]	-4	hSpCas9	positive selection	3775226
162411996	162412019	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.12482244573076862	[6]	[7,6]	3	hSpCas9	positive selection	3775227
162411904	162411927	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.18770105439551832	[5]	[6,6]	5	hSpCas9	positive selection	3775228
162411948	162411971	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGACCTTGCTGCTCAAGGAAGGG	SH2D1B	ENSG00000198574	0.18920376007068818	[5]	[6,5]	5	hSpCas9	positive selection	3775229
162411872	162411895	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.1598277459772639	[5]	[3,4]	-2	hSpCas9	positive selection	3883831
162402754	162402777	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	-0.252207011757258	[5]	[4,2]	-3	hSpCas9	positive selection	3883832
162402755	162402778	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	0.10301577243035406	[5]	[6,3]	2	hSpCas9	positive selection	3883833
162411996	162412019	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.13808226039527297	[6]	[5,6]	3	hSpCas9	positive selection	3883834
162411904	162411927	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.16538288318442457	[7]	[6,6]	4	hSpCas9	positive selection	3883835
162411948	162411971	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGACCTTGCTGCTCAAGGAAGGG	SH2D1B	ENSG00000198574	-0.6303789380241662	[5]	[1,2]	-7	hSpCas9	positive selection	3883836
162411904	162411927	1	-	26780180	A375	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	1.26547401600787	[]	[]	6	hSpCas9	negative selection	3993874
162402756	162402779	1	+	26780180	A375	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.763032898381301	[]	[]	3	hSpCas9	negative selection	3993875
162411977	162412000	1	+	26780180	A375	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	1.51828737978482	[]	[]	8	hSpCas9	negative selection	3993876
162397294	162397317	1	-	26780180	A375	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	0.613662435709018	[]	[]	2	hSpCas9	negative selection	3993877
162398999	162399022	1	+	26780180	A375	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	1.52721467139593	[]	[]	8	hSpCas9	negative selection	3993878
162399063	162399086	1	-	26780180	A375	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.760125275097225	[]	[]	3	hSpCas9	negative selection	3993879
162411904	162411927	1	-	26780180	HT29	viability (GeCKOv2 library)	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	1.66480095984717	[]	[]	8	hSpCas9	negative selection	4101840
162402756	162402779	1	+	26780180	HT29	viability (GeCKOv2 library)	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	1.03411107860335	[]	[]	5	hSpCas9	negative selection	4101841
162411977	162412000	1	+	26780180	HT29	viability (GeCKOv2 library)	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.645031649516462	[]	[]	2	hSpCas9	negative selection	4101842
162397294	162397317	1	-	26780180	HT29	viability (GeCKOv2 library)	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	1.28224490478946	[]	[]	6	hSpCas9	negative selection	4101843
162398999	162399022	1	+	26780180	HT29	viability (GeCKOv2 library)	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	1.25464019946894	[]	[]	6	hSpCas9	negative selection	4101844
162399063	162399086	1	-	26780180	HT29	viability (GeCKOv2 library)	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	1.03742946415356	[]	[]	5	hSpCas9	negative selection	4101845
162399045	162399068	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	-0.17245050771579118	[1]	[0,0]	-4	hSpCas9	positive selection	4169817
162402755	162402778	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.7899234779997419	[2]	[0,0]	-9	hSpCas9	positive selection	4169818
162402756	162402779	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.034681088345410616	[2]	[1,2]	0	hSpCas9	positive selection	4169819
162399077	162399100	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTATTTTTGCAGACTGCAGAAGG	SH2D1B	ENSG00000198574	0.18156545000233992	[1]	[0,1]	4	hSpCas9	positive selection	4169820
162398999	162399022	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.1707611072634992	[5]	[3,4]	4	hSpCas9	positive selection	4169821
162399045	162399068	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.9569876249489748	[0]	[0,0,0,0]	6	hSpCas9	positive selection	4233839
162402755	162402778	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	0.1612435086581837	[2]	[2,2,0,0]	1	hSpCas9	positive selection	4233840
162402756	162402779	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	-0.13005276516414022	[2]	[0,1,0,0]	-2	hSpCas9	positive selection	4233841
162399077	162399100	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTATTTTTGCAGACTGCAGAAGG	SH2D1B	ENSG00000198574	0.4669523404747522	[3]	[4,3,1,0]	3	hSpCas9	positive selection	4233842
162398999	162399022	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.33581194109900214	[5]	[6,3,5,0]	2	hSpCas9	positive selection	4233843
162411904	162411927	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.0586836591999145	[3]	[3,2]	-1	hSpCas9	positive selection	4297516
162411977	162412000	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.4192535642749196	[4]	[3,4]	8	hSpCas9	positive selection	4297517
162397294	162397317	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.029661789233968117	[3]	[3,1]	0	hSpCas9	positive selection	4297518
162398999	162399022	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	-0.13267276907769787	[3]	[2,1]	-3	hSpCas9	positive selection	4361770
162402756	162402779	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	-0.4070454152754286	[1]	[0,0]	-7	hSpCas9	positive selection	4361771
162399063	162399086	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.11785802220990674	[2]	[2,1]	2	hSpCas9	positive selection	4361772
162399006	162399028	1	-	27760321	OCIAML3	viability	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	0.8778503664167007	[147,147]	[192,239]	8	hSpCas9	negative selection	4438578
162399036	162399058	1	+	27760321	OCIAML3	viability	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.10844036328959217	[520,401]	[252,559]	1	hSpCas9	negative selection	4438579
162402738	162402760	1	-	27760321	OCIAML3	viability	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	0.38723565409054894	[292,192]	[219,277]	4	hSpCas9	negative selection	4438580
162402755	162402777	1	-	27760321	OCIAML3	viability	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	1.0033592528497464	[60,67]	[97,106]	9	hSpCas9	negative selection	4438581
162411879	162411901	1	+	27760321	OCIAML3	viability	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	0.20334637399911432	[626,493]	[375,664]	2	hSpCas9	negative selection	4438582
162399006	162399028	1	-	27760321	OCIAML2	viability	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	0.1874730897771557	[147,147]	[125,150]	2	hSpCas9	negative selection	4522041
162399036	162399058	1	+	27760321	OCIAML2	viability	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.09293057889094533	[520,401]	[459,309]	1	hSpCas9	negative selection	4522042
162402738	162402760	1	-	27760321	OCIAML2	viability	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	-0.36332810312739083	[292,192]	[126,181]	-4	hSpCas9	negative selection	4522043
162402755	162402777	1	-	27760321	OCIAML2	viability	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	0.8256230239895948	[60,67]	[106,74]	9	hSpCas9	negative selection	4522044
162411879	162411901	1	+	27760321	OCIAML2	viability	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	0.2467795417662874	[626,493]	[455,637]	3	hSpCas9	negative selection	4522045
162399006	162399028	1	-	27760321	MV411	viability	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	0.043706618244841344	[147,147]	[100,100]	0	hSpCas9	negative selection	4605504
162399036	162399058	1	+	27760321	MV411	viability	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	-0.07774400938397934	[520,401]	[118,537]	0	hSpCas9	negative selection	4605505
162402738	162402760	1	-	27760321	MV411	viability	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	-0.6873188094810424	[292,192]	[130,48]	-5	hSpCas9	negative selection	4605506
162402755	162402777	1	-	27760321	MV411	viability	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-3.353192177274745	[60,67]	[0,8]	-9	hSpCas9	negative selection	4605507
162411879	162411901	1	+	27760321	MV411	viability	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	-0.09510348177638134	[626,493]	[395,265]	0	hSpCas9	negative selection	4605508
162399006	162399028	1	-	27760321	HL60	viability	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	0.18251427764858907	[147,147]	[92,184]	2	hSpCas9	negative selection	4688967
162399036	162399058	1	+	27760321	HL60	viability	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.5778906186691501	[520,401]	[495,624]	7	hSpCas9	negative selection	4688968
162402738	162402760	1	-	27760321	HL60	viability	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	-1.2005856118300504	[292,192]	[74,95]	-8	hSpCas9	negative selection	4688969
162402755	162402777	1	-	27760321	HL60	viability	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.8543569588213993	[60,67]	[24,33]	-7	hSpCas9	negative selection	4688970
162411879	162411901	1	+	27760321	HL60	viability	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	0.5369944540362022	[626,493]	[677,640]	6	hSpCas9	negative selection	4688971
162399006	162399028	1	-	27760321	HT1080	viability	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	1.1438388062898248	[147,115]	[120,110]	6	hSpCas9	negative selection	4772430
162399036	162399058	1	+	27760321	HT1080	viability	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	1.4042952343328738	[401,313]	[461,284]	7	hSpCas9	negative selection	4772431
162402738	162402760	1	-	27760321	HT1080	viability	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	-1.0894285674023887	[192,150]	[25,38]	-4	hSpCas9	negative selection	4772432
162402755	162402777	1	-	27760321	HT1080	viability	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-1.5623073354568962	[67,52]	[0,15]	-5	hSpCas9	negative selection	4772433
162411879	162411901	1	+	27760321	HT1080	viability	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	-0.7016015728438099	[493,385]	[155,54]	-3	hSpCas9	negative selection	4772434
162399006	162399028	1	-	27760321	HT29	viability after 7 days	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	0.2518222510101651	[147,115]	[352,179,97]	4	hSpCas9	negative selection	4855893
162399036	162399058	1	+	27760321	HT29	viability after 7 days	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.40781124968461036	[401,313]	[704,509,628]	6	hSpCas9	negative selection	4855894
162402738	162402760	1	-	27760321	HT29	viability after 7 days	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	-0.3970586884053622	[192,150]	[134,165,196]	-5	hSpCas9	negative selection	4855895
162402755	162402777	1	-	27760321	HT29	viability after 7 days	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.4161438426519255	[67,52]	[52,29,89]	-6	hSpCas9	negative selection	4855896
162411879	162411901	1	+	27760321	HT29	viability after 7 days	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	0.14212306342395015	[493,385]	[616,755,501]	2	hSpCas9	negative selection	4855897
162399006	162399028	1	-	27760321	HT29	viability after 25 days	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	0.3453365110597122	[147,115]	[199,141,236]	3	hSpCas9	negative selection	4939356
162399036	162399058	1	+	27760321	HT29	viability after 25 days	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.6866775700687846	[401,313]	[708,366,922]	7	hSpCas9	negative selection	4939357
162402738	162402760	1	-	27760321	HT29	viability after 25 days	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	-0.013621195596859925	[192,150]	[139,212,238]	0	hSpCas9	negative selection	4939358
162402755	162402777	1	-	27760321	HT29	viability after 25 days	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.6525472202549549	[67,52]	[39,31,61]	-5	hSpCas9	negative selection	4939359
162411879	162411901	1	+	27760321	HT29	viability after 25 days	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	0.8874710120270768	[493,385]	[713,969,1140]	8	hSpCas9	negative selection	4939360
162399006	162399028	1	-	27760321	HT29	viability after 22 days	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	0.3241141379643184	[147,115]	[250,195,123]	3	hSpCas9	negative selection	5022819
162399036	162399058	1	+	27760321	HT29	viability after 22 days	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.4874788097887778	[401,313]	[521,362,859]	5	hSpCas9	negative selection	5022820
162402738	162402760	1	-	27760321	HT29	viability after 22 days	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	0.3681405967371423	[192,150]	[279,378,108]	4	hSpCas9	negative selection	5022821
162402755	162402777	1	-	27760321	HT29	viability after 22 days	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.42773192917575553	[67,52]	[80,41,31]	-4	hSpCas9	negative selection	5022822
162411879	162411901	1	+	27760321	HT29	viability after 22 days	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	0.8513840099591479	[493,385]	[668,871,1221]	8	hSpCas9	negative selection	5022823
162399006	162399028	1	-	27760321	HT29	viability after 19 days	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	0.553657616011364	[147,115]	[278,148,241]	5	hSpCas9	negative selection	5106282
162399036	162399058	1	+	27760321	HT29	viability after 19 days	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.6707569162882859	[401,313]	[640,449,854]	6	hSpCas9	negative selection	5106283
162402738	162402760	1	-	27760321	HT29	viability after 19 days	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	-0.5795874827737033	[192,150]	[172,142,84]	-5	hSpCas9	negative selection	5106284
162402755	162402777	1	-	27760321	HT29	viability after 19 days	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	0.15168178763231843	[67,52]	[48,31,143]	1	hSpCas9	negative selection	5106285
162411879	162411901	1	+	27760321	HT29	viability after 19 days	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	0.7126326696053953	[493,385]	[588,848,1003]	7	hSpCas9	negative selection	5106286
162399006	162399028	1	-	27760321	HT29	viability after 16 days	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	0.8599190118327615	[147,115]	[269,246,287]	8	hSpCas9	negative selection	5189745
162399036	162399058	1	+	27760321	HT29	viability after 16 days	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.36446690577064395	[401,313]	[678,567,313]	4	hSpCas9	negative selection	5189746
162402738	162402760	1	-	27760321	HT29	viability after 16 days	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	0.5904598359448612	[192,150]	[113,432,301]	6	hSpCas9	negative selection	5189747
162402755	162402777	1	-	27760321	HT29	viability after 16 days	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	0.49991670128557386	[67,52]	[117,65,105]	6	hSpCas9	negative selection	5189748
162411879	162411901	1	+	27760321	HT29	viability after 16 days	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	0.8019356485211235	[493,385]	[800,872,894]	8	hSpCas9	negative selection	5189749
162399006	162399028	1	-	27760321	HT29	viability after 13 days	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	0.3764608576777364	[147,115]	[169,149,271]	5	hSpCas9	negative selection	5273208
162399036	162399058	1	+	27760321	HT29	viability after 13 days	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.09062267111701108	[401,313]	[480,477,371]	1	hSpCas9	negative selection	5273209
162402738	162402760	1	-	27760321	HT29	viability after 13 days	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	-0.03205820818846816	[192,150]	[127,216,237]	0	hSpCas9	negative selection	5273210
162402755	162402777	1	-	27760321	HT29	viability after 13 days	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	-0.46807325102433417	[67,52]	[47,49,53]	-5	hSpCas9	negative selection	5273211
162411879	162411901	1	+	27760321	HT29	viability after 13 days	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	0.4986344514632244	[493,385]	[742,791,633]	6	hSpCas9	negative selection	5273212
162399006	162399028	1	-	27760321	HT29	viability after 10 days	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	0.6174333981220779	[147,115]	[304,235,217]	8	hSpCas9	negative selection	5356671
162399036	162399058	1	+	27760321	HT29	viability after 10 days	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.18238878872361539	[401,313]	[531,402,581]	2	hSpCas9	negative selection	5356672
162402738	162402760	1	-	27760321	HT29	viability after 10 days	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	-0.28203109618215993	[192,150]	[152,148,225]	-4	hSpCas9	negative selection	5356673
162402755	162402777	1	-	27760321	HT29	viability after 10 days	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	0.41947835825816426	[67,52]	[94,142,66]	6	hSpCas9	negative selection	5356674
162411879	162411901	1	+	27760321	HT29	viability after 10 days	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	1.036562517120334	[493,385]	[1363,1003,1011]	9	hSpCas9	negative selection	5356675
162399006	162399028	1	-	27760321	MOLM13	viability	GAAAAACCAAATCAGGGGATGG	SH2D1B	ENSG00000198574	0.2285066809586529	[147,147]	[122,76]	1	hSpCas9	negative selection	5440134
162399036	162399058	1	+	27760321	MOLM13	viability	AGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.8102330060679331	[520,401]	[402,495]	5	hSpCas9	negative selection	5440135
162402738	162402760	1	-	27760321	MOLM13	viability	CACGGGTATTACAGGATACAGG	SH2D1B	ENSG00000198574	0.83066477309644	[292,192]	[125,337]	6	hSpCas9	negative selection	5440136
162402755	162402777	1	-	27760321	MOLM13	viability	GAATCTTCAGAGAGAAACACGG	SH2D1B	ENSG00000198574	1.7890346846054557	[60,67]	[15,220]	9	hSpCas9	negative selection	5440137
162411879	162411901	1	+	27760321	MOLM13	viability	TCACGAGACACAGAGGCACAGG	SH2D1B	ENSG00000198574	0.5580302637113304	[626,493]	[501,428]	4	hSpCas9	negative selection	5440138
162412055	162412078	1	+	27661255	K562	viability	GAAATTCACCCCCAAGTCAAGGG	SH2D1B	ENSG00000198574	-0.020178710772161074	[730,609]	[605,464]	-1	dCas9-KRAB	negative selection	5510712
162411608	162411631	1	-	27661255	K562	viability	GAAGGGCTGCAGGAAGTACAGGG	SH2D1B	ENSG00000198574	0.16917790687969692	[1406,1480]	[1325,1269]	6	dCas9-KRAB	negative selection	5510713
162412111	162412134	1	-	27661255	K562	viability	GGAAGAGGTAGCTCCACAGGAGG	SH2D1B	ENSG00000198574	-0.10926762068466456	[576,433]	[399,355]	-4	dCas9-KRAB	negative selection	5510714
162411904	162411927	1	-	27260156	BXPC3	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.11089013145956961	[908]	[729,778,909,1151]	-3	hSpCas9	negative selection	5569976
162411977	162412000	1	+	27260156	BXPC3	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.09160290501173018	[1109]	[992,1326,1332,1317]	2	hSpCas9	negative selection	5569977
162397294	162397317	1	-	27260156	BXPC3	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.2763381714882621	[892]	[734,758,725,874]	-6	hSpCas9	negative selection	5569978
162398999	162399022	1	+	27260156	BXPC3	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.3740308511940789	[508]	[563,668,657,903]	7	hSpCas9	negative selection	5634230
162402756	162402779	1	+	27260156	BXPC3	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.22936801093486214	[113]	[84,167,151,159]	5	hSpCas9	negative selection	5634231
162399063	162399086	1	-	27260156	BXPC3	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.24031842406711101	[300]	[256,436,288,527]	5	hSpCas9	negative selection	5634232
162411904	162411927	1	-	27260156	A673	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.20150854803134688	[908]	[1161,829,868,962]	-5	hSpCas9	negative selection	5691227
162411977	162412000	1	+	27260156	A673	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.14419500678635022	[1109]	[1331,1202,1115,1184]	-4	hSpCas9	negative selection	5691228
162397294	162397317	1	-	27260156	A673	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.3882787453621216	[892]	[983,913,606,786]	-7	hSpCas9	negative selection	5691229
162398999	162399022	1	+	27260156	A673	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.09620610817815105	[508]	[644,595,584,794]	2	hSpCas9	negative selection	5755481
162402756	162402779	1	+	27260156	A673	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.20448535705294502	[113]	[143,223,127,129]	5	hSpCas9	negative selection	5755482
162399063	162399086	1	-	27260156	A673	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.2083654393595183	[300]	[618,299,378,396]	5	hSpCas9	negative selection	5755483
162411904	162411927	1	-	27260156	A375	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.16302072887351937	[908]	[1081,1104,758,874]	-2	hSpCas9	negative selection	5812478
162411977	162412000	1	+	27260156	A375	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.08695714141132016	[1109]	[1164,1504,1248,1021]	-1	hSpCas9	negative selection	5812479
162397294	162397317	1	-	27260156	A375	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.564016098698777	[892]	[800,804,523,703]	-6	hSpCas9	negative selection	5812480
162398999	162399022	1	+	27260156	A375	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.13776444396132814	[508]	[699,918,507,537]	2	hSpCas9	negative selection	5876732
162402756	162402779	1	+	27260156	A375	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.28158428870108976	[113]	[203,213,89,147]	4	hSpCas9	negative selection	5876733
162399063	162399086	1	-	27260156	A375	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.3173794999090688	[300]	[428,620,583,173]	4	hSpCas9	negative selection	5876734
162411904	162411927	1	-	27260156	COLO741	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.073545684347467	[908]	[1347,1365,978]	1	hSpCas9	negative selection	5933729
162411977	162412000	1	+	27260156	COLO741	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.15962864636471696	[1109]	[1237,1328,1238]	-3	hSpCas9	negative selection	5933730
162397294	162397317	1	-	27260156	COLO741	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.6468635594174934	[892]	[817,590,778]	-8	hSpCas9	negative selection	5933731
162398999	162399022	1	+	27260156	COLO741	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.41403735824390026	[508]	[953,952,709]	8	hSpCas9	negative selection	5997983
162402756	162402779	1	+	27260156	COLO741	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.3926425401815483	[113]	[112,237,213]	7	hSpCas9	negative selection	5997984
162399063	162399086	1	-	27260156	COLO741	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.3663304731874832	[300]	[404,484,581]	7	hSpCas9	negative selection	5997985
162411904	162411927	1	-	27260156	CAL120	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.2586996372042504	[908]	[1929,911,1304]	4	hSpCas9	negative selection	6054980
162411977	162412000	1	+	27260156	CAL120	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.12611149475552108	[1109]	[1593,1106,1146]	-2	hSpCas9	negative selection	6054981
162397294	162397317	1	-	27260156	CAL120	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-1.0212564877362231	[892]	[672,544,444]	-8	hSpCas9	negative selection	6054982
162398999	162399022	1	+	27260156	CAL120	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.31752236881851936	[508]	[953,680,757]	5	hSpCas9	negative selection	6119234
162402756	162402779	1	+	27260156	CAL120	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.6822250492976212	[113]	[218,206,254]	8	hSpCas9	negative selection	6119235
162399063	162399086	1	-	27260156	CAL120	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.7313318135083897	[300]	[840,478,578]	9	hSpCas9	negative selection	6119236
162411904	162411927	1	-	27260156	CADOES1	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.05780453372781513	[908]	[890,875,793,961]	1	hSpCas9	negative selection	6176231
162411977	162412000	1	+	27260156	CADOES1	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.03583307548413539	[1109]	[1123,999,1254,845]	0	hSpCas9	negative selection	6176232
162397294	162397317	1	-	27260156	CADOES1	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.44221209597134875	[892]	[595,681,538,628]	-7	hSpCas9	negative selection	6176233
162398999	162399022	1	+	27260156	CADOES1	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.08107844571468238	[508]	[547,368,575,509]	1	hSpCas9	negative selection	6240485
162402756	162402779	1	+	27260156	CADOES1	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.8306709325767976	[113]	[87,219,170,278]	9	hSpCas9	negative selection	6240486
162399063	162399086	1	-	27260156	CADOES1	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.28445930505492	[300]	[254,267,445,396]	5	hSpCas9	negative selection	6240487
162411904	162411927	1	-	27260156	EWS502	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.18588184161061194	[908]	[1064,979,940,1419]	3	hSpCas9	negative selection	6297482
162411977	162412000	1	+	27260156	EWS502	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.007061420865601242	[1109]	[1049,1209,1289,1187]	0	hSpCas9	negative selection	6297483
162397294	162397317	1	-	27260156	EWS502	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.2788504769124748	[892]	[741,780,792,805]	-5	hSpCas9	negative selection	6297484
162398999	162399022	1	+	27260156	EWS502	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.15013026919329303	[508]	[544,453,662,752]	2	hSpCas9	negative selection	6361736
162402756	162402779	1	+	27260156	EWS502	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.42513091316145335	[113]	[94,227,174,154]	7	hSpCas9	negative selection	6361737
162399063	162399086	1	-	27260156	EWS502	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.4380471790721787	[300]	[351,400,547,437]	7	hSpCas9	negative selection	6361738
162411904	162411927	1	-	27260156	EW8	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.40932619772066814	[908]	[735,459,523,521]	-6	hSpCas9	negative selection	6418733
162411977	162412000	1	+	27260156	EW8	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.12429088395463017	[1109]	[1189,826,947,981]	2	hSpCas9	negative selection	6418734
162397294	162397317	1	-	27260156	EW8	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.6969095794830126	[892]	[552,435,358,462]	-8	hSpCas9	negative selection	6418735
162398999	162399022	1	+	27260156	EW8	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.33734071700302837	[508]	[422,553,516,578]	6	hSpCas9	negative selection	6482987
162402756	162402779	1	+	27260156	EW8	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.7061670011409411	[113]	[235,122,95,165]	9	hSpCas9	negative selection	6482988
162399063	162399086	1	-	27260156	EW8	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.4112310635168884	[300]	[297,255,384,343]	7	hSpCas9	negative selection	6482989
162411904	162411927	1	-	27260156	CORL105	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.016922700363885212	[908]	[1065,1005,1258,909]	0	hSpCas9	negative selection	6539984
162411977	162412000	1	+	27260156	CORL105	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.08327029924839424	[1109]	[1379,1494,1504,1144]	1	hSpCas9	negative selection	6539985
162397294	162397317	1	-	27260156	CORL105	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.4766777948189124	[892]	[742,712,731,813]	-7	hSpCas9	negative selection	6539986
162398999	162399022	1	+	27260156	CORL105	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.11842413867751596	[508]	[625,677,684,602]	2	hSpCas9	negative selection	6604238
162402756	162402779	1	+	27260156	CORL105	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.3007436620558732	[113]	[187,98,242,141]	5	hSpCas9	negative selection	6604239
162399063	162399086	1	-	27260156	CORL105	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.05798549419269561	[300]	[283,447,380,351]	1	hSpCas9	negative selection	6604240
162411904	162411927	1	-	27260156	HS294T	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.09907981538510346	[908]	[401,319,301,270]	-1	hSpCas9	negative selection	6661235
162411977	162412000	1	+	27260156	HS294T	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.09428819328808902	[1109]	[353,414,309,557]	-1	hSpCas9	negative selection	6661236
162397294	162397317	1	-	27260156	HS294T	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.38660723048990864	[892]	[288,223,254,290]	-5	hSpCas9	negative selection	6661237
162398999	162399022	1	+	27260156	HS294T	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	-0.4247825088431139	[508]	[95,149,156,195]	-6	hSpCas9	negative selection	6725489
162402756	162402779	1	+	27260156	HS294T	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	-0.4360758524474351	[113]	[25,39,39,22]	-6	hSpCas9	negative selection	6725490
162399063	162399086	1	-	27260156	HS294T	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	-0.32340702955561784	[300]	[112,71,84,101]	-4	hSpCas9	negative selection	6725491
162411904	162411927	1	-	27260156	HCC44	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.12945994580555176	[908]	[1089,947,1330,1175]	2	hSpCas9	negative selection	6782486
162411977	162412000	1	+	27260156	HCC44	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.18787209747469147	[1109]	[1531,1125,1484,1620]	3	hSpCas9	negative selection	6782487
162397294	162397317	1	-	27260156	HCC44	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.6434983357346812	[892]	[783,438,718,691]	-7	hSpCas9	negative selection	6782488
162398999	162399022	1	+	27260156	HCC44	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.28365331127191745	[508]	[530,613,875,799]	4	hSpCas9	negative selection	6846740
162402756	162402779	1	+	27260156	HCC44	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.3024533392604609	[113]	[65,155,199,209]	5	hSpCas9	negative selection	6846741
162399063	162399086	1	-	27260156	HCC44	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.3221693940554941	[300]	[446,360,603,331]	5	hSpCas9	negative selection	6846742
162411904	162411927	1	-	27260156	G402	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.13950339197045525	[908]	[1018,1328,852,850]	-2	hSpCas9	negative selection	6903737
162411977	162412000	1	+	27260156	G402	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.017809095049294177	[1109]	[1189,1258,1775,1228]	0	hSpCas9	negative selection	6903738
162397294	162397317	1	-	27260156	G402	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.2445457446118825	[892]	[924,828,829,1078]	-3	hSpCas9	negative selection	6903739
162398999	162399022	1	+	27260156	G402	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	-0.061263699506392856	[508]	[720,330,489,827]	-1	hSpCas9	negative selection	6967991
162402756	162402779	1	+	27260156	G402	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.21476641639071037	[113]	[335,88,119,122]	2	hSpCas9	negative selection	6967992
162399063	162399086	1	-	27260156	G402	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	1.0157856246034371	[300]	[1120,767,671,475]	9	hSpCas9	negative selection	6967993
162411904	162411927	1	-	27260156	L33	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.227094337147423	[908]	[768,351,527,639]	-5	hSpCas9	negative selection	7024988
162411977	162412000	1	+	27260156	L33	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.022128022443133277	[1109]	[1089,408,755,1081]	0	hSpCas9	negative selection	7024989
162397294	162397317	1	-	27260156	L33	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.20844338566405252	[892]	[889,305,475,694]	-5	hSpCas9	negative selection	7024990
162398999	162399022	1	+	27260156	L33	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.28045044580408857	[508]	[547,292,407,562]	6	hSpCas9	negative selection	7089242
162402756	162402779	1	+	27260156	L33	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	-0.46013165867932937	[113]	[97,22,60,79]	-8	hSpCas9	negative selection	7089243
162399063	162399086	1	-	27260156	L33	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.315487657037085	[300]	[358,155,211,420]	6	hSpCas9	negative selection	7089244
162411904	162411927	1	-	27260156	K562	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.32704761277942196	[908]	[592,808,716,474]	-4	hSpCas9	negative selection	7146239
162411977	162412000	1	+	27260156	K562	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.1674994846801905	[1109]	[991,1022,755,763]	-2	hSpCas9	negative selection	7146240
162397294	162397317	1	-	27260156	K562	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.5451631755551618	[892]	[662,439,542,529]	-6	hSpCas9	negative selection	7146241
162398999	162399022	1	+	27260156	K562	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.12669855710758637	[508]	[698,475,341,471]	1	hSpCas9	negative selection	7210493
162402756	162402779	1	+	27260156	K562	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.45523524407443094	[113]	[223,221,50,75]	6	hSpCas9	negative selection	7210494
162399063	162399086	1	-	27260156	K562	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.07038539146950096	[300]	[278,412,168,267]	0	hSpCas9	negative selection	7210495
162411904	162411927	1	-	27260156	HT29	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.19491283614637	[908]	[1185,942,977,784]	-4	hSpCas9	negative selection	7267490
162411977	162412000	1	+	27260156	HT29	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.11790968360216003	[1109]	[1420,1457,1656,1323]	2	hSpCas9	negative selection	7267491
162397294	162397317	1	-	27260156	HT29	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.3314734568218827	[892]	[1010,1240,513,737]	-6	hSpCas9	negative selection	7267492
162398999	162399022	1	+	27260156	HT29	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.1882745113495859	[508]	[840,597,697,681]	3	hSpCas9	negative selection	7331744
162402756	162402779	1	+	27260156	HT29	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.00908962386205614	[113]	[139,192,102,126]	0	hSpCas9	negative selection	7331745
162399063	162399086	1	-	27260156	HT29	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.49996707045263433	[300]	[648,694,468,304]	8	hSpCas9	negative selection	7331746
162411904	162411927	1	-	27260156	MHHES1	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.27265371312972586	[908]	[955,898,753,791]	-5	hSpCas9	negative selection	7388741
162411977	162412000	1	+	27260156	MHHES1	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.17412299553225408	[1109]	[1184,1467,1010,848]	-3	hSpCas9	negative selection	7388742
162397294	162397317	1	-	27260156	MHHES1	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.0752875716972029	[892]	[1063,1341,714,769]	-1	hSpCas9	negative selection	7388743
162398999	162399022	1	+	27260156	MHHES1	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	-0.16485590361064992	[508]	[535,584,449,479]	-3	hSpCas9	negative selection	7452995
162402756	162402779	1	+	27260156	MHHES1	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.04763554725047214	[113]	[50,199,101,163]	0	hSpCas9	negative selection	7452996
162399063	162399086	1	-	27260156	MHHES1	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.08513497092608968	[300]	[404,371,398,279]	1	hSpCas9	negative selection	7452997
162411904	162411927	1	-	27260156	MEWO	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.2497231720123534	[908]	[945,574,669]	-5	hSpCas9	negative selection	7509992
162411977	162412000	1	+	27260156	MEWO	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.09153729532239452	[1109]	[969,928,1023]	-2	hSpCas9	negative selection	7509993
162397294	162397317	1	-	27260156	MEWO	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.3188000860370813	[892]	[667,863,475]	-6	hSpCas9	negative selection	7509994
162398999	162399022	1	+	27260156	MEWO	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	-0.0074323213198642935	[508]	[588,367,486]	0	hSpCas9	negative selection	7574246
162402756	162402779	1	+	27260156	MEWO	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.8500974892894706	[113]	[238,147,198]	9	hSpCas9	negative selection	7574247
162399063	162399086	1	-	27260156	MEWO	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.1906646447054337	[300]	[338,221,406]	4	hSpCas9	negative selection	7574248
162411904	162411927	1	-	27260156	LNCAPCLONEFGC	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.17067782712653057	[908]	[784,760,746,631]	-3	hSpCas9	negative selection	7631243
162411977	162412000	1	+	27260156	LNCAPCLONEFGC	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.06214629978665731	[1109]	[965,761,1144,1018]	-1	hSpCas9	negative selection	7631244
162397294	162397317	1	-	27260156	LNCAPCLONEFGC	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.7570783337337617	[892]	[505,481,461,460]	-8	hSpCas9	negative selection	7631245
162398999	162399022	1	+	27260156	LNCAPCLONEFGC	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	-0.04428052907817097	[508]	[453,390,555,406]	0	hSpCas9	negative selection	7695497
162402756	162402779	1	+	27260156	LNCAPCLONEFGC	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	-0.1420867711948941	[113]	[117,83,83,86]	-2	hSpCas9	negative selection	7695498
162399063	162399086	1	-	27260156	LNCAPCLONEFGC	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.2263834025187409	[300]	[268,318,475,235]	3	hSpCas9	negative selection	7695499
162411904	162411927	1	-	27260156	PANC0327	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.08219582063777742	[908]	[1152,637,663,1015]	1	hSpCas9	negative selection	7752494
162411977	162412000	1	+	27260156	PANC0327	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.1995720132113603	[1109]	[978,730,1022,727]	-3	hSpCas9	negative selection	7752495
162397294	162397317	1	-	27260156	PANC0327	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	0.023868064755538154	[892]	[486,1333,539,769]	0	hSpCas9	negative selection	7752496
162398999	162399022	1	+	27260156	PANC0327	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.838369203995639	[508]	[1721,456,745,428]	9	hSpCas9	negative selection	7816748
162402756	162402779	1	+	27260156	PANC0327	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.27616709060598565	[113]	[68,131,182,100]	4	hSpCas9	negative selection	7816749
162399063	162399086	1	-	27260156	PANC0327	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.40484267338061464	[300]	[745,228,223,264]	6	hSpCas9	negative selection	7816750
162411904	162411927	1	-	27260156	NCIH2009	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.09732087757459984	[908]	[1169,1266,1600]	1	hSpCas9	negative selection	7873745
162411977	162412000	1	+	27260156	NCIH2009	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.05945807129394387	[1109]	[1566,1362,1549]	-1	hSpCas9	negative selection	7873746
162397294	162397317	1	-	27260156	NCIH2009	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.1740148710575964	[892]	[1445,941,997]	-2	hSpCas9	negative selection	7873747
162398999	162399022	1	+	27260156	NCIH2009	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.18222322768835397	[508]	[742,954,705]	2	hSpCas9	negative selection	7937999
162402756	162402779	1	+	27260156	NCIH2009	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	-0.058669610496024927	[113]	[86,69,289]	-1	hSpCas9	negative selection	7938000
162399063	162399086	1	-	27260156	NCIH2009	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.723954417458853	[300]	[519,812,712]	8	hSpCas9	negative selection	7938001
162411904	162411927	1	-	27260156	NCIH1373	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.15910541179652682	[908]	[1259,609,1515,323]	1	hSpCas9	negative selection	7994996
162411977	162412000	1	+	27260156	NCIH1373	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.16703388189950386	[1109]	[1152,1078,1415,199]	-2	hSpCas9	negative selection	7994997
162397294	162397317	1	-	27260156	NCIH1373	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.020987282244940397	[892]	[1375,906,945,201]	0	hSpCas9	negative selection	7994998
162398999	162399022	1	+	27260156	NCIH1373	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.02593326453026966	[508]	[528,687,530,144]	0	hSpCas9	negative selection	8059250
162402756	162402779	1	+	27260156	NCIH1373	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.262925714876292	[113]	[203,152,160,25]	2	hSpCas9	negative selection	8059251
162399063	162399086	1	-	27260156	NCIH1373	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.37996519153396235	[300]	[572,500,301,102]	4	hSpCas9	negative selection	8059252
162411904	162411927	1	-	27260156	PATU8902	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.03560534809302962	[908]	[1595,1324,786,1641]	0	hSpCas9	negative selection	8116247
162411977	162412000	1	+	27260156	PATU8902	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.019265364760715054	[1109]	[2519,1000,982,1930]	0	hSpCas9	negative selection	8116248
162397294	162397317	1	-	27260156	PATU8902	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.6399546603352737	[892]	[762,442,601,1513]	-6	hSpCas9	negative selection	8116249
162398999	162399022	1	+	27260156	PATU8902	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.42309680979063785	[508]	[1509,928,858,452]	4	hSpCas9	negative selection	8180501
162402756	162402779	1	+	27260156	PATU8902	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.7037369534392961	[113]	[326,325,90,340]	7	hSpCas9	negative selection	8180502
162399063	162399086	1	-	27260156	PATU8902	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.525330277966542	[300]	[819,872,448,263]	5	hSpCas9	negative selection	8180503
162411904	162411927	1	-	27260156	PANC1	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.3185947934326011	[908]	[843,1147,1097,848]	5	hSpCas9	negative selection	8237498
162411977	162412000	1	+	27260156	PANC1	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.3347974348603524	[1109]	[1020,1532,1186,1131]	5	hSpCas9	negative selection	8237499
162397294	162397317	1	-	27260156	PANC1	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.19309399423693074	[892]	[971,562,616,516]	-3	hSpCas9	negative selection	8237500
162398999	162399022	1	+	27260156	PANC1	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.48814181694474806	[508]	[588,874,614,445]	7	hSpCas9	negative selection	8301752
162402756	162402779	1	+	27260156	PANC1	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.9509735932369043	[113]	[224,102,279,136]	9	hSpCas9	negative selection	8301753
162399063	162399086	1	-	27260156	PANC1	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.5581708895828277	[300]	[370,426,335,389]	8	hSpCas9	negative selection	8301754
162411904	162411927	1	-	27260156	PANC0813	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.041655051481940375	[908]	[1012,995,982,1146]	0	hSpCas9	negative selection	8358749
162411977	162412000	1	+	27260156	PANC0813	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.6074625420055337	[1109]	[1875,2717,1948,1420]	8	hSpCas9	negative selection	8358750
162397294	162397317	1	-	27260156	PANC0813	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.27740639000314904	[892]	[1050,876,825,730]	-4	hSpCas9	negative selection	8358751
162398999	162399022	1	+	27260156	PANC0813	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	-0.13449007723296622	[508]	[502,482,532,648]	-2	hSpCas9	negative selection	8423003
162402756	162402779	1	+	27260156	PANC0813	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	-0.1721010055414398	[113]	[140,120,110,104]	-3	hSpCas9	negative selection	8423004
162399063	162399086	1	-	27260156	PANC0813	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.23730753626856765	[300]	[490,362,500,323]	4	hSpCas9	negative selection	8423005
162411904	162411927	1	-	27260156	RDES	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.19055748612376233	[908]	[826,812,993,1053]	-3	hSpCas9	negative selection	8480000
162411977	162412000	1	+	27260156	RDES	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.07836662622457857	[1109]	[962,1179,1419,1316]	-1	hSpCas9	negative selection	8480001
162397294	162397317	1	-	27260156	RDES	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.534200087761161	[892]	[591,557,609,1160]	-7	hSpCas9	negative selection	8480002
162398999	162399022	1	+	27260156	RDES	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.034178579669576895	[508]	[445,645,691,632]	0	hSpCas9	negative selection	8544254
162402756	162402779	1	+	27260156	RDES	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.10316118780534111	[113]	[74,168,128,207]	1	hSpCas9	negative selection	8544255
162399063	162399086	1	-	27260156	RDES	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.2971762833267801	[300]	[331,347,508,549]	5	hSpCas9	negative selection	8544256
162411904	162411927	1	-	27260156	PC3	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.2583447223665236	[908]	[549,658,1220,794]	-5	hSpCas9	negative selection	8601251
162411977	162412000	1	+	27260156	PC3	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.0038861029882217846	[1109]	[891,963,1626,1099]	0	hSpCas9	negative selection	8601252
162397294	162397317	1	-	27260156	PC3	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.28148798099455086	[892]	[534,659,1424,581]	-6	hSpCas9	negative selection	8601253
162398999	162399022	1	+	27260156	PC3	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.14051177900457357	[508]	[393,550,759,624]	3	hSpCas9	negative selection	8665505
162402756	162402779	1	+	27260156	PC3	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	1.0432808101619633	[113]	[211,173,445,165]	9	hSpCas9	negative selection	8665506
162399063	162399086	1	-	27260156	PC3	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.4803189669004997	[300]	[195,420,603,598]	8	hSpCas9	negative selection	8665507
162411904	162411927	1	-	27260156	PATU8988T	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.014921760238724047	[908]	[794,886,916,879]	0	hSpCas9	negative selection	8722502
162411977	162412000	1	+	27260156	PATU8988T	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.042381952927284194	[1109]	[1025,1334,940,1142]	0	hSpCas9	negative selection	8722503
162397294	162397317	1	-	27260156	PATU8988T	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.5332914960917308	[892]	[445,845,435,689]	-7	hSpCas9	negative selection	8722504
162398999	162399022	1	+	27260156	PATU8988T	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.37466631200926465	[508]	[574,629,676,669]	6	hSpCas9	negative selection	8786756
162402756	162402779	1	+	27260156	PATU8988T	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.08870969337695023	[113]	[62,105,127,174]	1	hSpCas9	negative selection	8786757
162399063	162399086	1	-	27260156	PATU8988T	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	-0.049279177903937876	[300]	[247,277,301,296]	-1	hSpCas9	negative selection	8786758
162411904	162411927	1	-	27260156	T47D	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.3189296101417308	[908]	[700,890,899,899]	-6	hSpCas9	negative selection	8843753
162411977	162412000	1	+	27260156	T47D	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.07596415505754162	[1109]	[1170,1217,1215,1304]	-2	hSpCas9	negative selection	8843754
162397294	162397317	1	-	27260156	T47D	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.387194485957137	[892]	[812,852,631,883]	-7	hSpCas9	negative selection	8843755
162398999	162399022	1	+	27260156	T47D	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.21669777854771938	[508]	[638,713,616,787]	4	hSpCas9	negative selection	8908007
162402756	162402779	1	+	27260156	T47D	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.20169206506109671	[113]	[150,143,152,163]	4	hSpCas9	negative selection	8908008
162399063	162399086	1	-	27260156	T47D	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.35616353338517154	[300]	[428,349,488,537]	7	hSpCas9	negative selection	8908009
162411904	162411927	1	-	27260156	SU8686	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	0.004304431560612332	[908]	[729,743,1189,1010]	0	hSpCas9	negative selection	8965004
162411977	162412000	1	+	27260156	SU8686	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.13194737870129947	[1109]	[1213,869,1308,1517]	2	hSpCas9	negative selection	8965005
162397294	162397317	1	-	27260156	SU8686	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	0.010149878533354584	[892]	[771,719,841,1331]	0	hSpCas9	negative selection	8965006
162398999	162399022	1	+	27260156	SU8686	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.31435806746657274	[508]	[601,485,616,858]	5	hSpCas9	negative selection	9029258
162402756	162402779	1	+	27260156	SU8686	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	-0.2400237166958057	[113]	[70,70,87,169]	-4	hSpCas9	negative selection	9029259
162399063	162399086	1	-	27260156	SU8686	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.4483392257887655	[300]	[320,290,439,636]	7	hSpCas9	negative selection	9029260
162411904	162411927	1	-	27260156	SKES1	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.1329025215216626	[908]	[1029,1020,661,659]	-3	hSpCas9	negative selection	9086255
162411977	162412000	1	+	27260156	SKES1	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.031202166054584257	[1109]	[1471,1168,953,824]	0	hSpCas9	negative selection	9086256
162397294	162397317	1	-	27260156	SKES1	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.5510763633395428	[892]	[644,621,589,578]	-8	hSpCas9	negative selection	9086257
162398999	162399022	1	+	27260156	SKES1	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.2011710702065826	[508]	[675,681,511,494]	4	hSpCas9	negative selection	9150509
162402756	162402779	1	+	27260156	SKES1	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.17869075350550334	[113]	[168,108,141,99]	4	hSpCas9	negative selection	9150510
162399063	162399086	1	-	27260156	SKES1	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.14584079924644033	[300]	[338,291,336,350]	3	hSpCas9	negative selection	9150511
162411904	162411927	1	-	27260156	TOV112D	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.051300611167359844	[908]	[884,823,873,915]	-1	hSpCas9	negative selection	9207506
162411977	162412000	1	+	27260156	TOV112D	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.22694262560255218	[1109]	[1150,2177,904,1174]	4	hSpCas9	negative selection	9207507
162397294	162397317	1	-	27260156	TOV112D	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.6088360324247909	[892]	[697,785,571,353]	-8	hSpCas9	negative selection	9207508
162398999	162399022	1	+	27260156	TOV112D	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.1884195228549394	[508]	[555,908,415,521]	3	hSpCas9	negative selection	9271760
162402756	162402779	1	+	27260156	TOV112D	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.7838678499669465	[113]	[215,236,162,181]	9	hSpCas9	negative selection	9271761
162399063	162399086	1	-	27260156	TOV112D	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.41836832680511093	[300]	[658,626,230,176]	7	hSpCas9	negative selection	9271762
162411904	162411927	1	-	27260156	TC71	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.16274638240470563	[908]	[903,890,714,982]	-4	hSpCas9	negative selection	9328757
162411977	162412000	1	+	27260156	TC71	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.026068793645608324	[1109]	[1282,1106,1216,1238]	0	hSpCas9	negative selection	9328758
162397294	162397317	1	-	27260156	TC71	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.3162580446789913	[892]	[656,842,731,851]	-7	hSpCas9	negative selection	9328759
162398999	162399022	1	+	27260156	TC71	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	0.1672141026156876	[508]	[632,615,677,514]	4	hSpCas9	negative selection	9393011
162402756	162402779	1	+	27260156	TC71	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	0.22094371254170708	[113]	[150,100,108,213]	5	hSpCas9	negative selection	9393012
162399063	162399086	1	-	27260156	TC71	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	0.10421319456765554	[300]	[349,287,374,374]	2	hSpCas9	negative selection	9393013
162411904	162411927	1	-	27260156	TC32	viability	AGAGACAGCGAGTCGATACCAGG	SH2D1B	ENSG00000198574	-0.20289691826735046	[908]	[730,522,917,874]	-4	hSpCas9	negative selection	9450008
162411977	162412000	1	+	27260156	TC32	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.293726735200754	[1109]	[758,625,960,1139]	-5	hSpCas9	negative selection	9450009
162397294	162397317	1	-	27260156	TC32	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.7243112350503411	[892]	[414,379,711,595]	-8	hSpCas9	negative selection	9450010
162398999	162399022	1	+	27260156	TC32	viability	TGAACCACCATCCCCTGATTTGG	SH2D1B	ENSG00000198574	-0.38589485730936796	[508]	[321,225,519,466]	-6	hSpCas9	negative selection	9514262
162402756	162402779	1	+	27260156	TC32	viability	CGTGTTTCTCTCTGAAGATTCGG	SH2D1B	ENSG00000198574	-0.25264332854542815	[113]	[108,26,145,104]	-4	hSpCas9	negative selection	9514263
162399063	162399086	1	-	27260156	TC32	viability	TGCAGAAGGTTCTCCAAAACAGG	SH2D1B	ENSG00000198574	-0.034799945833751345	[300]	[184,261,389,287]	0	hSpCas9	negative selection	9514264
162411872	162411895	1	+	27869803	HPAFII	viability after 27 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.31543264396977844	[362]	[148,156,NaN]	-2	hSpCas9	negative selection	9530173
162411872	162411895	1	+	27869803	HPAFII	viability after 15 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.08861461830297557	[362]	[494,364,NaN]	1	hSpCas9	negative selection	9612622
162411872	162411895	1	+	27869803	ASPC1	viability after 36 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.19172785639172713	[810]	[434,267,97]	-2	hSpCas9	negative selection	9695071
162411872	162411895	1	+	27869803	PATU8988S	viability after 35 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.5922111043194003	[703]	[403,450,NaN]	6	hSpCas9	negative selection	9777520
162411872	162411895	1	+	27869803	PATU8988S	viability after 31 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.34011082719316094	[703]	[280,449,NaN]	4	hSpCas9	negative selection	9859969
162411872	162411895	1	+	27869803	HPAFII	viability after 35 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.23190899374532248	[362]	[196,236,NaN]	1	hSpCas9	negative selection	9942418
162411872	162411895	1	+	27869803	HPAFII	viability after 31 days	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.10663179491041941	[362]	[204,171,NaN]	0	hSpCas9	negative selection	10024867
162411944	162411967	1	-	28162770	P31FUJ	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	-0.5970765900113357	[120]	[93]	-5	hSpCas9	negative selection	10233425
162398947	162398970	1	+	28162770	P31FUJ	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	-0.22153109207935828	[509]	[513]	-2	hSpCas9	negative selection	10233426
162402754	162402777	1	-	28162770	P31FUJ	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	0.28942454095881487	[93]	[134]	3	hSpCas9	negative selection	10233427
162411872	162411895	1	+	28162770	P31FUJ	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.2311448953454116	[28]	[39]	2	hSpCas9	negative selection	10233428
162411996	162412019	1	+	28162770	P31FUJ	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.1339801262572441	[227]	[293]	1	hSpCas9	negative selection	10233429
162399003	162399026	1	-	28162770	P31FUJ	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	0.23497675693643827	[234]	[324]	2	hSpCas9	negative selection	10233430
162399035	162399058	1	+	28162770	P31FUJ	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.38572544723212165	[438]	[673]	4	hSpCas9	negative selection	10233431
162399045	162399068	1	-	28162770	P31FUJ	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.4766076672312659	[147]	[241]	5	hSpCas9	negative selection	10233432
162411977	162412000	1	+	28162770	P31FUJ	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.3649615785298671	[373]	[565]	4	hSpCas9	negative selection	10233433
162397294	162397317	1	-	28162770	P31FUJ	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.16209921307117675	[218]	[229]	-1	hSpCas9	negative selection	10233434
162411944	162411967	1	-	28162770	TF1	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10402791
162398947	162398970	1	+	28162770	TF1	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	NaN	[NaN]	[496]	1	hSpCas9	negative selection	10402792
162402754	162402777	1	-	28162770	TF1	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10402793
162411872	162411895	1	+	28162770	TF1	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10402794
162411996	162412019	1	+	28162770	TF1	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	NaN	[NaN]	[392]	1	hSpCas9	negative selection	10402795
162399003	162399026	1	-	28162770	TF1	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	NaN	[NaN]	[188]	1	hSpCas9	negative selection	10402796
162399035	162399058	1	+	28162770	TF1	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	NaN	[NaN]	[581]	1	hSpCas9	negative selection	10402797
162399045	162399068	1	-	28162770	TF1	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10402798
162411977	162412000	1	+	28162770	TF1	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	NaN	[NaN]	[365]	1	hSpCas9	negative selection	10402799
162397294	162397317	1	-	28162770	TF1	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	NaN	[NaN]	[219]	1	hSpCas9	negative selection	10402800
162411944	162411967	1	-	28162770	SKM1	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	-1.0146467759644011	[23]	[20]	-6	hSpCas9	negative selection	10572157
162398947	162398970	1	+	28162770	SKM1	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	-0.2704621988382996	[130]	[191]	-2	hSpCas9	negative selection	10572158
162402754	162402777	1	-	28162770	SKM1	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	-0.47407839460169865	[43]	[55]	-4	hSpCas9	negative selection	10572159
162411872	162411895	1	+	28162770	SKM1	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.00112053989391514	[12]	[22]	0	hSpCas9	negative selection	10572160
162411996	162412019	1	+	28162770	SKM1	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.2719744501870081	[51]	[110]	2	hSpCas9	negative selection	10572161
162399003	162399026	1	-	28162770	SKM1	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	-0.3049432618026531	[57]	[82]	-3	hSpCas9	negative selection	10572162
162399035	162399058	1	+	28162770	SKM1	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.26700330803673944	[109]	[233]	2	hSpCas9	negative selection	10572163
162399045	162399068	1	-	28162770	SKM1	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.5316352565926947	[17]	[45]	5	hSpCas9	negative selection	10572164
162411977	162412000	1	+	28162770	SKM1	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.09723655746132631	[94]	[156]	-1	hSpCas9	negative selection	10572165
162397294	162397317	1	-	28162770	SKM1	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.046707985196699955	[51]	[88]	0	hSpCas9	negative selection	10572166
162411944	162411967	1	-	28162770	SKM1	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	-1.0146467759644011	[23]	[20]	-6	hSpCas9	negative selection	10741523
162398947	162398970	1	+	28162770	SKM1	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	-0.2704621988382996	[130]	[191]	-2	hSpCas9	negative selection	10741524
162402754	162402777	1	-	28162770	SKM1	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	-0.47407839460169865	[43]	[55]	-4	hSpCas9	negative selection	10741525
162411872	162411895	1	+	28162770	SKM1	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.00112053989391514	[12]	[22]	0	hSpCas9	negative selection	10741526
162411996	162412019	1	+	28162770	SKM1	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.2719744501870081	[51]	[110]	2	hSpCas9	negative selection	10741527
162399003	162399026	1	-	28162770	SKM1	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	-0.3049432618026531	[57]	[82]	-3	hSpCas9	negative selection	10741528
162399035	162399058	1	+	28162770	SKM1	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.26700330803673944	[109]	[233]	2	hSpCas9	negative selection	10741529
162399045	162399068	1	-	28162770	SKM1	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.5316352565926947	[17]	[45]	5	hSpCas9	negative selection	10741530
162411977	162412000	1	+	28162770	SKM1	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.09723655746132631	[94]	[156]	-1	hSpCas9	negative selection	10741531
162397294	162397317	1	-	28162770	SKM1	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.046707985196699955	[51]	[88]	0	hSpCas9	negative selection	10741532
162411944	162411967	1	-	28162770	PL21	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	1.7385595292734461	[83]	[121]	9	hSpCas9	negative selection	10910889
162398947	162398970	1	+	28162770	PL21	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	0.18454275943830156	[464]	[229]	1	hSpCas9	negative selection	10910890
162402754	162402777	1	-	28162770	PL21	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	0.3256704965731792	[142]	[77]	3	hSpCas9	negative selection	10910891
162411872	162411895	1	+	28162770	PL21	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	1.422532035825768	[35]	[41]	9	hSpCas9	negative selection	10910892
162411996	162412019	1	+	28162770	PL21	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	-0.5072195175915628	[208]	[63]	-4	hSpCas9	negative selection	10910893
162399003	162399026	1	-	28162770	PL21	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	0.3181029518436098	[222]	[120]	3	hSpCas9	negative selection	10910894
162399035	162399058	1	+	28162770	PL21	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.23509221332374475	[366]	[187]	2	hSpCas9	negative selection	10910895
162399045	162399068	1	-	28162770	PL21	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	1.5452751005380077	[110]	[140]	9	hSpCas9	negative selection	10910896
162411977	162412000	1	+	28162770	PL21	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-1.315217418745969	[262]	[45]	-7	hSpCas9	negative selection	10910897
162397294	162397317	1	-	28162770	PL21	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	0.856837868809391	[84]	[66]	7	hSpCas9	negative selection	10910898
162411944	162411967	1	-	28162770	P31FUJ	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	-0.5970765900113357	[120]	[93]	-5	hSpCas9	negative selection	11080255
162398947	162398970	1	+	28162770	P31FUJ	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	-0.22153109207935828	[509]	[513]	-2	hSpCas9	negative selection	11080256
162402754	162402777	1	-	28162770	P31FUJ	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	0.28942454095881487	[93]	[134]	3	hSpCas9	negative selection	11080257
162411872	162411895	1	+	28162770	P31FUJ	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.2311448953454116	[28]	[39]	2	hSpCas9	negative selection	11080258
162411996	162412019	1	+	28162770	P31FUJ	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.1339801262572441	[227]	[293]	1	hSpCas9	negative selection	11080259
162399003	162399026	1	-	28162770	P31FUJ	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	0.23497675693643827	[234]	[324]	2	hSpCas9	negative selection	11080260
162399035	162399058	1	+	28162770	P31FUJ	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.38572544723212165	[438]	[673]	4	hSpCas9	negative selection	11080261
162399045	162399068	1	-	28162770	P31FUJ	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.4766076672312659	[147]	[241]	5	hSpCas9	negative selection	11080262
162411977	162412000	1	+	28162770	P31FUJ	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.3649615785298671	[373]	[565]	4	hSpCas9	negative selection	11080263
162397294	162397317	1	-	28162770	P31FUJ	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.16209921307117675	[218]	[229]	-1	hSpCas9	negative selection	11080264
162411944	162411967	1	-	28162770	OCIAML5	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	-2.151626852722904	[31]	[12]	-8	hSpCas9	negative selection	11249621
162398947	162398970	1	+	28162770	OCIAML5	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	-0.26241237481811863	[306]	[461]	-2	hSpCas9	negative selection	11249622
162402754	162402777	1	-	28162770	OCIAML5	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	-1.1516268527229048	[111]	[90]	-6	hSpCas9	negative selection	11249623
162411872	162411895	1	+	28162770	OCIAML5	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.401690021381786	[12]	[30]	3	hSpCas9	negative selection	11249624
162411996	162412019	1	+	28162770	OCIAML5	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	-0.18748690207947277	[93]	[148]	-1	hSpCas9	negative selection	11249625
162399003	162399026	1	-	28162770	OCIAML5	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	0.6389197816481453	[147]	[415]	5	hSpCas9	negative selection	11249626
162399035	162399058	1	+	28162770	OCIAML5	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.059747903383806866	[311]	[586]	0	hSpCas9	negative selection	11249627
162399045	162399068	1	-	28162770	OCIAML5	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.7206696275238997	[78]	[234]	6	hSpCas9	negative selection	11249628
162411977	162412000	1	+	28162770	OCIAML5	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.34991001391835663	[182]	[420]	3	hSpCas9	negative selection	11249629
162397294	162397317	1	-	28162770	OCIAML5	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	0.5396204411374662	[108]	[285]	5	hSpCas9	negative selection	11249630
162411944	162411967	1	-	28162770	EOL1	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	0.594842326091453	[92]	[73]	5	hSpCas9	negative selection	11418987
162398947	162398970	1	+	28162770	EOL1	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	0.4001268127844292	[419]	[291]	3	hSpCas9	negative selection	11418988
162402754	162402777	1	-	28162770	EOL1	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	0.20755687716559457	[262]	[159]	2	hSpCas9	negative selection	11418989
162411872	162411895	1	+	28162770	EOL1	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.2871178509552428	[83]	[53]	2	hSpCas9	negative selection	11418990
162411996	162412019	1	+	28162770	EOL1	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	-0.28223245073130665	[336]	[145]	-2	hSpCas9	negative selection	11418991
162399003	162399026	1	-	28162770	EOL1	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	0.456330234432516	[349]	[252]	4	hSpCas9	negative selection	11418992
162399035	162399058	1	+	28162770	EOL1	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.5181491905655634	[443]	[334]	5	hSpCas9	negative selection	11418993
162399045	162399068	1	-	28162770	EOL1	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.8692653360693449	[132]	[127]	7	hSpCas9	negative selection	11418994
162411977	162412000	1	+	28162770	EOL1	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	-0.13547699950168296	[318]	[152]	-1	hSpCas9	negative selection	11418995
162397294	162397317	1	-	28162770	EOL1	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	1.1517814559764816	[169]	[198]	8	hSpCas9	negative selection	11418996
162411944	162411967	1	-	28162770	MOLM13	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	-1.288839467443057	[97]	[28]	-6	hSpCas9	negative selection	11588353
162398947	162398970	1	+	28162770	MOLM13	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	0.1020394318932667	[691]	[536]	0	hSpCas9	negative selection	11588354
162402754	162402777	1	-	28162770	MOLM13	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	1.052851882265735	[183]	[275]	7	hSpCas9	negative selection	11588355
162411872	162411895	1	+	28162770	MOLM13	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.7591206792090246	[75]	[92]	6	hSpCas9	negative selection	11588356
162411996	162412019	1	+	28162770	MOLM13	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.26339271371004	[226]	[196]	2	hSpCas9	negative selection	11588357
162399003	162399026	1	-	28162770	MOLM13	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	1.1467882829773046	[217]	[348]	8	hSpCas9	negative selection	11588358
162399035	162399058	1	+	28162770	MOLM13	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.5253312737862684	[516]	[537]	4	hSpCas9	negative selection	11588359
162399045	162399068	1	-	28162770	MOLM13	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	-0.21964285281712514	[152]	[94]	-1	hSpCas9	negative selection	11588360
162411977	162412000	1	+	28162770	MOLM13	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.6811334206668415	[338]	[392]	5	hSpCas9	negative selection	11588361
162397294	162397317	1	-	28162770	MOLM13	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.3552328563713417	[229]	[129]	-2	hSpCas9	negative selection	11588362
162411944	162411967	1	-	28162770	HEL	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	-1.357261167999643	[87]	[21]	-7	hSpCas9	negative selection	11757719
162398947	162398970	1	+	28162770	HEL	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	-0.18358628230449292	[554]	[312]	-1	hSpCas9	negative selection	11757720
162402754	162402777	1	-	28162770	HEL	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	-0.37043655674737624	[219]	[108]	-3	hSpCas9	negative selection	11757721
162411872	162411895	1	+	28162770	HEL	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	1.2948155285800502	[55]	[87]	9	hSpCas9	negative selection	11757722
162411996	162412019	1	+	28162770	HEL	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.5753109044800664	[218]	[208]	5	hSpCas9	negative selection	11757723
162399003	162399026	1	-	28162770	HEL	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	0.03745634689960481	[285]	[187]	0	hSpCas9	negative selection	11757724
162399035	162399058	1	+	28162770	HEL	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.1644777234071202	[481]	[345]	1	hSpCas9	negative selection	11757725
162399045	162399068	1	-	28162770	HEL	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.8993754666360001	[112]	[134]	7	hSpCas9	negative selection	11757726
162411977	162412000	1	+	28162770	HEL	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.8269178171229112	[234]	[266]	7	hSpCas9	negative selection	11757727
162397294	162397317	1	-	28162770	HEL	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.13486874666319523	[215]	[125]	-1	hSpCas9	negative selection	11757728
162411944	162411967	1	-	28162770	MV411	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	-1.0537319839377894	[68]	[27]	-6	hSpCas9	negative selection	11927085
162398947	162398970	1	+	28162770	MV411	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	0.6304849358171822	[341]	[445]	6	hSpCas9	negative selection	11927086
162402754	162402777	1	-	28162770	MV411	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	-0.2340953602829754	[147]	[105]	-2	hSpCas9	negative selection	11927087
162411872	162411895	1	+	28162770	MV411	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	1.4637554577095386	[33]	[78]	9	hSpCas9	negative selection	11927088
162411996	162412019	1	+	28162770	MV411	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.1268474099691868	[211]	[194]	1	hSpCas9	negative selection	11927089
162399003	162399026	1	-	28162770	MV411	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	0.746615348212829	[178]	[252]	6	hSpCas9	negative selection	11927090
162399035	162399058	1	+	28162770	MV411	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.3945418448149859	[353]	[391]	3	hSpCas9	negative selection	11927091
162399045	162399068	1	-	28162770	MV411	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.2980636238527433	[83]	[86]	2	hSpCas9	negative selection	11927092
162411977	162412000	1	+	28162770	MV411	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.40918862077938756	[235]	[263]	3	hSpCas9	negative selection	11927093
162397294	162397317	1	-	28162770	MV411	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	0.8749246681504887	[155]	[240]	7	hSpCas9	negative selection	11927094
162411944	162411967	1	-	28162770	MONOMAC1	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	0.3111100566107716	[44]	[63]	3	hSpCas9	negative selection	12096451
162398947	162398970	1	+	28162770	MONOMAC1	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	0.24320120634443276	[226]	[307]	2	hSpCas9	negative selection	12096452
162402754	162402777	1	-	28162770	MONOMAC1	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	-0.27103742850333057	[59]	[56]	-2	hSpCas9	negative selection	12096453
162411872	162411895	1	+	28162770	MONOMAC1	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.897476565200646	[12]	[7]	-6	hSpCas9	negative selection	12096454
162411996	162412019	1	+	28162770	MONOMAC1	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.5054192166800431	[109]	[178]	5	hSpCas9	negative selection	12096455
162399003	162399026	1	-	28162770	MONOMAC1	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	-0.6390413939386668	[143]	[105]	-5	hSpCas9	negative selection	12096456
162399035	162399058	1	+	28162770	MONOMAC1	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	-0.10229635708914397	[220]	[235]	-1	hSpCas9	negative selection	12096457
162399045	162399068	1	-	28162770	MONOMAC1	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.37719924706854435	[44]	[66]	4	hSpCas9	negative selection	12096458
162411977	162412000	1	+	28162770	MONOMAC1	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.5048069539572215	[157]	[256]	5	hSpCas9	negative selection	12096459
162397294	162397317	1	-	28162770	MONOMAC1	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	0.9569967816128672	[70]	[157]	8	hSpCas9	negative selection	12096460
162411944	162411967	1	-	28162770	OCIAML2	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	-1.16806705522173	[14]	[36]	-6	hSpCas9	negative selection	12265817
162398947	162398970	1	+	28162770	OCIAML2	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	0.22786162110940933	[56]	[369]	2	hSpCas9	negative selection	12265818
162402754	162402777	1	-	28162770	OCIAML2	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	-1.358736945171264	[30]	[66]	-7	hSpCas9	negative selection	12265819
162411872	162411895	1	+	28162770	OCIAML2	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	-0.7336642310759549	[8]	[29]	-5	hSpCas9	negative selection	12265820
162411996	162412019	1	+	28162770	OCIAML2	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	0.5477487040726934	[38]	[315]	5	hSpCas9	negative selection	12265821
162399003	162399026	1	-	28162770	OCIAML2	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	0.24959250508946842	[38]	[256]	2	hSpCas9	negative selection	12265822
162399035	162399058	1	+	28162770	OCIAML2	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.567125096753257	[65]	[541]	5	hSpCas9	negative selection	12265823
162399045	162399068	1	-	28162770	OCIAML2	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.840956325423742	[13]	[138]	7	hSpCas9	negative selection	12265824
162411977	162412000	1	+	28162770	OCIAML2	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.9489090662716233	[29]	[320]	8	hSpCas9	negative selection	12265825
162397294	162397317	1	-	28162770	OCIAML2	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	-0.21124319642351172	[32]	[157]	-2	hSpCas9	negative selection	12265826
162411944	162411967	1	-	28162770	OCIAML3	viability	CTTGCTGCTCAAGGAAGGGGTGG	SH2D1B	ENSG00000198574	-0.032128752716048314	[20]	[61]	0	hSpCas9	negative selection	12435183
162398947	162398970	1	+	28162770	OCIAML3	viability	CAATCCTCTCCATCTCAAGCTGG	SH2D1B	ENSG00000198574	0.7976793716772999	[108]	[571]	7	hSpCas9	negative selection	12435184
162402754	162402777	1	-	28162770	OCIAML3	viability	GAATCTTCAGAGAGAAACACGGG	SH2D1B	ENSG00000198574	-0.8636147000814434	[43]	[72]	-6	hSpCas9	negative selection	12435185
162411872	162411895	1	+	28162770	OCIAML3	viability	AGGCTACTCACGAGACACAGAGG	SH2D1B	ENSG00000198574	0.7983097824545973	[7]	[41]	7	hSpCas9	negative selection	12435186
162411996	162412019	1	+	28162770	OCIAML3	viability	ATGGTAGTAAGGCAGATCCATGG	SH2D1B	ENSG00000198574	-0.6379509879117603	[49]	[96]	-5	hSpCas9	negative selection	12435187
162399003	162399026	1	-	28162770	OCIAML3	viability	AAAACCAAATCAGGGGATGGTGG	SH2D1B	ENSG00000198574	0.5136330828638067	[70]	[305]	5	hSpCas9	negative selection	12435188
162399035	162399058	1	+	28162770	OCIAML3	viability	GAGATCAGTTCCTTTAGGCTTGG	SH2D1B	ENSG00000198574	0.3728254957406376	[98]	[386]	3	hSpCas9	negative selection	12435189
162399045	162399068	1	-	28162770	OCIAML3	viability	ACAGGTCTTTCCAAGCCTAAAGG	SH2D1B	ENSG00000198574	0.2424936273929572	[20]	[74]	2	hSpCas9	negative selection	12435190
162411977	162412000	1	+	28162770	OCIAML3	viability	CTTGCTTGGTCAGACGTCCATGG	SH2D1B	ENSG00000198574	0.45150701892820577	[77]	[321]	4	hSpCas9	negative selection	12435191
162397294	162397317	1	-	28162770	OCIAML3	viability	GAACAGTAACAGCGATTATGTGG	SH2D1B	ENSG00000198574	1.1532262892958702	[34]	[234]	8	hSpCas9	negative selection	12435192