Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6725
• Symbol: SRMS
• Description: src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites

DataSource: http://genomecrispr.dkfz.de/#!/results/SRMS

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
63547240	63547263	20	-	26472758	Jiyoye	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	-0.6879818515344669	[140]	[65]	-5	hSpCas9	negative selection	156335
63544300	63544323	20	+	26472758	Jiyoye	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	-0.4236973472578675	[200]	[112]	-3	hSpCas9	negative selection	156336
63542497	63542520	20	-	26472758	Jiyoye	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	0.059252078085566484	[83]	[65]	0	hSpCas9	negative selection	156337
63547308	63547331	20	+	26472758	Jiyoye	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	-0.2366808082688512	[124]	[79]	-2	hSpCas9	negative selection	156338
63547286	63547309	20	+	26472758	Jiyoye	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	1.6398361382961486	[39]	[93]	8	hSpCas9	negative selection	156339
63542292	63542315	20	-	26472758	Jiyoye	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	0.33943077487003914	[108]	[103]	2	hSpCas9	negative selection	156340
63541540	63541563	20	-	26472758	Jiyoye	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	0.32917286950460034	[265]	[251]	2	hSpCas9	negative selection	156341
63547393	63547416	20	-	26472758	Jiyoye	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	-0.5928246184941264	[17]	[8]	-4	hSpCas9	negative selection	156342
63547165	63547188	20	-	26472758	Jiyoye	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	-0.17778711921528279	[71]	[47]	-1	hSpCas9	negative selection	156343
63547240	63547263	20	-	26472758	KBM7	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	1.0867226443067246	[351,230]	[430,156]	9	hSpCas9	negative selection	347453
63544300	63544323	20	+	26472758	KBM7	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.5316815550335174	[801,623]	[493,468]	6	hSpCas9	negative selection	347454
63542497	63542520	20	-	26472758	KBM7	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	-0.4379898571493842	[241,232]	[69,93]	-4	hSpCas9	negative selection	347455
63547308	63547331	20	+	26472758	KBM7	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	0.6456548461460258	[380,201]	[260,161]	7	hSpCas9	negative selection	347456
63547286	63547309	20	+	26472758	KBM7	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	0.14410195909009904	[330,364]	[227,141]	1	hSpCas9	negative selection	347457
63542292	63542315	20	-	26472758	KBM7	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	0.1212970904271124	[714,613]	[435,251]	1	hSpCas9	negative selection	347458
63541540	63541563	20	-	26472758	KBM7	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	-0.16259870263081644	[1173,1193]	[448,545]	-1	hSpCas9	negative selection	347459
63547393	63547416	20	-	26472758	KBM7	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	1.3881226704139844	[128,110]	[264,41]	9	hSpCas9	negative selection	347460
63547165	63547188	20	-	26472758	KBM7	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	0.4880871408700283	[443,306]	[258,230]	5	hSpCas9	negative selection	347461
63547240	63547263	20	-	26472758	Raji	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	0.2075476972990315	[152]	[40]	2	hSpCas9	negative selection	538571
63544300	63544323	20	+	26472758	Raji	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.2768832766681345	[376]	[105]	2	hSpCas9	negative selection	538572
63542497	63542520	20	-	26472758	Raji	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	1.559895740071106	[75]	[51]	9	hSpCas9	negative selection	538573
63547308	63547331	20	+	26472758	Raji	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	0.43151253845423293	[130]	[40]	4	hSpCas9	negative selection	538574
63547286	63547309	20	+	26472758	Raji	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	0.7854554404862372	[99]	[39]	7	hSpCas9	negative selection	538575
63542292	63542315	20	-	26472758	Raji	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	0.2616568024434768	[380]	[105]	2	hSpCas9	negative selection	538576
63541540	63541563	20	-	26472758	Raji	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	0.13028393748367817	[499]	[126]	1	hSpCas9	negative selection	538577
63547393	63547416	20	-	26472758	Raji	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	0.2879557810154202	[119]	[33]	2	hSpCas9	negative selection	538578
63547165	63547188	20	-	26472758	Raji	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	0.5880093762800201	[128]	[44]	5	hSpCas9	negative selection	538579
63547240	63547263	20	-	26472758	K562	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	-0.11265117334117258	[186]	[145]	-1	hSpCas9	negative selection	729689
63544300	63544323	20	+	26472758	K562	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.20081395835279248	[570]	[553]	1	hSpCas9	negative selection	729690
63542497	63542520	20	-	26472758	K562	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	-0.8409727635641977	[260]	[122]	-5	hSpCas9	negative selection	729691
63547308	63547331	20	+	26472758	K562	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	0.27466501453456743	[235]	[240]	2	hSpCas9	negative selection	729692
63547286	63547309	20	+	26472758	K562	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	0.4370638056088427	[314]	[359]	3	hSpCas9	negative selection	729693
63542292	63542315	20	-	26472758	K562	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	0.9108840131311009	[389]	[618]	7	hSpCas9	negative selection	729694
63541540	63541563	20	-	26472758	K562	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	-1.865014513419498	[793]	[183]	-7	hSpCas9	negative selection	729695
63547393	63547416	20	-	26472758	K562	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	-0.7884958948062881	[132]	[64]	-5	hSpCas9	negative selection	729696
63547165	63547188	20	-	26472758	K562	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	0.7342239953472628	[234]	[329]	6	hSpCas9	negative selection	729697
63541485	63541508	20	-	26627737	DLD1	viability	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-0.4926651894293952	[2286]	[636,522,383]	-5	hSpCas9	negative selection	815600
63542225	63542248	20	-	26627737	DLD1	viability	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	0.5323327089215482	[401]	[146,282,127]	5	hSpCas9	negative selection	815601
63542518	63542541	20	-	26627737	DLD1	viability	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	-0.08950852514886587	[174]	[57,73,26]	-1	hSpCas9	negative selection	815602
63544332	63544355	20	-	26627737	DLD1	viability	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.6076435907124229	[1636]	[571,1119,677]	6	hSpCas9	negative selection	815603
63547397	63547420	20	-	26627737	DLD1	viability	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.31963227886811096	[667]	[133,239,135]	-3	hSpCas9	negative selection	815604
63541485	63541508	20	-	26627737	GBM cells	viability after 5 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-0.6567594461536712	[706]	[271,208]	-8	hSpCas9	negative selection	897915
63542225	63542248	20	-	26627737	GBM cells	viability after 5 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	0.2644312383207308	[162]	[100,108]	4	hSpCas9	negative selection	897916
63542518	63542541	20	-	26627737	GBM cells	viability after 5 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	0.4118651306914536	[88]	[69,56]	6	hSpCas9	negative selection	897917
63544332	63544355	20	-	26627737	GBM cells	viability after 5 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.13935333497457125	[975]	[575,576]	2	hSpCas9	negative selection	897918
63547397	63547420	20	-	26627737	GBM cells	viability after 5 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	0.17377371611626893	[242]	[163,129]	2	hSpCas9	negative selection	897919
63541485	63541508	20	-	26627737	GBM cells	viability after 13 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-0.8637724833038022	[706]	[212,208]	-7	hSpCas9	negative selection	980230
63542225	63542248	20	-	26627737	GBM cells	viability after 13 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	0.6795318048567327	[162]	[123,155]	8	hSpCas9	negative selection	980231
63542518	63542541	20	-	26627737	GBM cells	viability after 13 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	0.9704070720144489	[88]	[87,99]	9	hSpCas9	negative selection	980232
63544332	63544355	20	-	26627737	GBM cells	viability after 13 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.30108607012981525	[975]	[802,529]	4	hSpCas9	negative selection	980233
63547397	63547420	20	-	26627737	GBM cells	viability after 13 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	0.3129008211109787	[242]	[208,126]	4	hSpCas9	negative selection	980234
63541485	63541508	20	-	26627737	GBM cells	viability after 21 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-1.212322984999497	[706]	[182,149]	-7	hSpCas9	negative selection	1062545
63542225	63542248	20	-	26627737	GBM cells	viability after 21 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	0.6446684969662703	[162]	[127,147]	6	hSpCas9	negative selection	1062546
63542518	63542541	20	-	26627737	GBM cells	viability after 21 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	0.9543059239568005	[88]	[100,86]	8	hSpCas9	negative selection	1062547
63544332	63544355	20	-	26627737	GBM cells	viability after 21 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.2775225655531035	[975]	[672,614]	3	hSpCas9	negative selection	1062548
63547397	63547420	20	-	26627737	GBM cells	viability after 21 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.3925708184519389	[242]	[98,101]	-4	hSpCas9	negative selection	1062549
63541485	63541508	20	-	26627737	RPE1	viability after 9 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-0.5837244710610114	[2329]	[439,546]	-4	hSpCas9	negative selection	1144860
63542225	63542248	20	-	26627737	RPE1	viability after 9 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	1.5269512070195972	[233]	[80,378]	8	hSpCas9	negative selection	1144861
63542518	63542541	20	-	26627737	RPE1	viability after 9 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	-0.08442717011415435	[421]	[52,216]	0	hSpCas9	negative selection	1144862
63544332	63544355	20	-	26627737	RPE1	viability after 9 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.5440959676160537	[3038]	[1395,1375]	3	hSpCas9	negative selection	1144863
63547397	63547420	20	-	26627737	RPE1	viability after 9 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.23247080666941577	[1172]	[350,262]	-2	hSpCas9	negative selection	1144864
63541485	63541508	20	-	26627737	RPE1	viability after 12 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-0.6204090766801719	[2329]	[277,543]	-4	hSpCas9	negative selection	1227175
63542225	63542248	20	-	26627737	RPE1	viability after 12 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	1.2203628575420624	[233]	[145,146]	7	hSpCas9	negative selection	1227176
63542518	63542541	20	-	26627737	RPE1	viability after 12 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	-0.5222509471665219	[421]	[76,80]	-4	hSpCas9	negative selection	1227177
63544332	63544355	20	-	26627737	RPE1	viability after 12 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.7896124466767762	[3038]	[1746,1055]	5	hSpCas9	negative selection	1227178
63547397	63547420	20	-	26627737	RPE1	viability after 12 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.08527921745046141	[1172]	[332,258]	0	hSpCas9	negative selection	1227179
63541485	63541508	20	-	26627737	RPE1	viability after 15 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-0.6864783483059588	[2329]	[209,601]	-4	hSpCas9	negative selection	1309490
63542225	63542248	20	-	26627737	RPE1	viability after 15 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	1.4988196062807315	[233]	[154,217]	7	hSpCas9	negative selection	1309491
63542518	63542541	20	-	26627737	RPE1	viability after 15 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	-1.1019381960252645	[421]	[20,88]	-6	hSpCas9	negative selection	1309492
63544332	63544355	20	-	26627737	RPE1	viability after 15 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.8813144135340318	[3038]	[1861,1314]	5	hSpCas9	negative selection	1309493
63547397	63547420	20	-	26627737	RPE1	viability after 15 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	0.6637370429425894	[1172]	[769,289]	4	hSpCas9	negative selection	1309494
63541485	63541508	20	-	26627737	RPE1	viability after 18 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-0.11484032171102942	[2329]	[381,792]	0	hSpCas9	negative selection	1391805
63542225	63542248	20	-	26627737	RPE1	viability after 18 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	1.9081910315138075	[233]	[193,282]	8	hSpCas9	negative selection	1391806
63542518	63542541	20	-	26627737	RPE1	viability after 18 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	0.13511894361710397	[421]	[126,122]	0	hSpCas9	negative selection	1391807
63544332	63544355	20	-	26627737	RPE1	viability after 18 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.6071351716181208	[3038]	[1445,1038]	4	hSpCas9	negative selection	1391808
63547397	63547420	20	-	26627737	RPE1	viability after 18 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	0.37644262222811575	[1172]	[612,194]	2	hSpCas9	negative selection	1391809
63541485	63541508	20	-	26627737	HeLa	viability after 8 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-0.3566901901975197	[742]	[237,244,269]	-3	hSpCas9	negative selection	1474120
63542225	63542248	20	-	26627737	HeLa	viability after 8 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	-0.7157346998022984	[438]	[197,38,128]	-6	hSpCas9	negative selection	1474121
63542518	63542541	20	-	26627737	HeLa	viability after 8 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	1.963243017196546	[44]	[158,22,65]	9	hSpCas9	negative selection	1474122
63544332	63544355	20	-	26627737	HeLa	viability after 8 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	-0.732208888675637	[2166]	[944,288,552]	-6	hSpCas9	negative selection	1474123
63547397	63547420	20	-	26627737	HeLa	viability after 8 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.27415565498741234	[495]	[306,126,132]	-3	hSpCas9	negative selection	1474124
63541485	63541508	20	-	26627737	HeLa	viability after 12 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	0.7097645379809556	[742]	[691,408,420]	6	hSpCas9	negative selection	1556435
63542225	63542248	20	-	26627737	HeLa	viability after 12 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	0.03154675241611646	[438]	[305,126,132]	0	hSpCas9	negative selection	1556436
63542518	63542541	20	-	26627737	HeLa	viability after 12 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	2.0073808252200225	[44]	[41,96,81]	9	hSpCas9	negative selection	1556437
63544332	63544355	20	-	26627737	HeLa	viability after 12 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	-0.5757452010325848	[2166]	[523,386,911]	-5	hSpCas9	negative selection	1556438
63547397	63547420	20	-	26627737	HeLa	viability after 12 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.7175166238182444	[495]	[76,233,49]	-6	hSpCas9	negative selection	1556439
63541485	63541508	20	-	26627737	HeLa	viability after 15 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	0.022535742549397386	[742]	[325,293,300]	0	hSpCas9	negative selection	1638750
63542225	63542248	20	-	26627737	HeLa	viability after 15 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	0.0020712289247746263	[438]	[336,89,101]	0	hSpCas9	negative selection	1638751
63542518	63542541	20	-	26627737	HeLa	viability after 15 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	1.8286561816526823	[44]	[3,126,64]	9	hSpCas9	negative selection	1638752
63544332	63544355	20	-	26627737	HeLa	viability after 15 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	-0.41284717600402976	[2166]	[932,333,721]	-4	hSpCas9	negative selection	1638753
63547397	63547420	20	-	26627737	HeLa	viability after 15 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	0.21634156173799368	[495]	[342,237,111]	1	hSpCas9	negative selection	1638754
63541485	63541508	20	-	26627737	HeLa	viability after 18 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	0.047219127118002024	[742]	[222,250,300]	0	hSpCas9	negative selection	1721065
63542225	63542248	20	-	26627737	HeLa	viability after 18 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	0.009783582891098624	[438]	[229,71,101]	0	hSpCas9	negative selection	1721066
63542518	63542541	20	-	26627737	HeLa	viability after 18 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	1.784548548173949	[44]	[2,99,64]	9	hSpCas9	negative selection	1721067
63544332	63544355	20	-	26627737	HeLa	viability after 18 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	-0.46534615463851137	[2166]	[585,268,721]	-4	hSpCas9	negative selection	1721068
63547397	63547420	20	-	26627737	HeLa	viability after 18 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	0.2445253819739256	[495]	[227,210,111]	2	hSpCas9	negative selection	1721069
63541485	63541508	20	-	26627737	HCT116	viability after 6 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	0.9019495354662896	[1825]	[547,529]	5	hSpCas9	negative selection	1803380
63542225	63542248	20	-	26627737	HCT116	viability after 6 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	1.8622539431799865	[352]	[19,301]	8	hSpCas9	negative selection	1803381
63542518	63542541	20	-	26627737	HCT116	viability after 6 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	1.3996324927738064	[94]	[21,48]	7	hSpCas9	negative selection	1803382
63544332	63544355	20	-	26627737	HCT116	viability after 6 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.41814260645858914	[3269]	[1023,500]	2	hSpCas9	negative selection	1803383
63547397	63547420	20	-	26627737	HCT116	viability after 6 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.10129648475697961	[1083]	[348,53]	0	hSpCas9	negative selection	1803384
63541485	63541508	20	-	26627737	HCT116	viability after 8 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	1.0357678860771546	[518]	[558,490,706]	8	hSpCas9	negative selection	1885695
63542225	63542248	20	-	26627737	HCT116	viability after 8 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	0.8644082919064953	[143]	[160,154,117]	7	hSpCas9	negative selection	1885696
63542518	63542541	20	-	26627737	HCT116	viability after 8 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	1.6246846697720727	[48]	[137,48,63]	9	hSpCas9	negative selection	1885697
63544332	63544355	20	-	26627737	HCT116	viability after 8 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.6326032599344946	[1034]	[1021,828,804]	6	hSpCas9	negative selection	1885698
63547397	63547420	20	-	26627737	HCT116	viability after 8 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	0.31099364464435175	[402]	[252,210,360]	3	hSpCas9	negative selection	1885699
63541485	63541508	20	-	26627737	HCT116	viability after 9 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-0.599291098021667	[1825]	[351,297]	-4	hSpCas9	negative selection	1968010
63542225	63542248	20	-	26627737	HCT116	viability after 9 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	-0.8503672147144631	[352]	[20,76]	-5	hSpCas9	negative selection	1968011
63542518	63542541	20	-	26627737	HCT116	viability after 9 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	0.7841898750687444	[94]	[60,29]	5	hSpCas9	negative selection	1968012
63544332	63544355	20	-	26627737	HCT116	viability after 9 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.18840229209334947	[3269]	[1147,873]	1	hSpCas9	negative selection	1968013
63547397	63547420	20	-	26627737	HCT116	viability after 9 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-1.6725102095711544	[1083]	[106,77]	-8	hSpCas9	negative selection	1968014
63541485	63541508	20	-	26627737	HCT116	viability after 12 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	1.137899238442846	[518]	[831,423,519]	8	hSpCas9	negative selection	2050325
63542225	63542248	20	-	26627737	HCT116	viability after 12 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	0.37876120383739764	[143]	[105,76,110]	4	hSpCas9	negative selection	2050326
63542518	63542541	20	-	26627737	HCT116	viability after 12 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	2.338887005310632	[48]	[246,23,106]	9	hSpCas9	negative selection	2050327
63544332	63544355	20	-	26627737	HCT116	viability after 12 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.4919801200871572	[1034]	[618,777,910]	5	hSpCas9	negative selection	2050328
63547397	63547420	20	-	26627737	HCT116	viability after 12 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	0.14704846323671428	[402]	[243,122,332]	1	hSpCas9	negative selection	2050329
63541485	63541508	20	-	26627737	HCT116	viability after 15 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	0.9478330675921468	[518]	[839,499,418]	7	hSpCas9	negative selection	2132640
63542225	63542248	20	-	26627737	HCT116	viability after 15 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	-0.2356920788276229	[143]	[90,115,6]	-2	hSpCas9	negative selection	2132641
63542518	63542541	20	-	26627737	HCT116	viability after 15 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	1.2121013794590856	[48]	[114,50,35]	8	hSpCas9	negative selection	2132642
63544332	63544355	20	-	26627737	HCT116	viability after 15 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.5533984390107902	[1034]	[1133,746,768]	5	hSpCas9	negative selection	2132643
63547397	63547420	20	-	26627737	HCT116	viability after 15 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	0.20116432066042056	[402]	[296,240,263]	2	hSpCas9	negative selection	2132644
63541485	63541508	20	-	26627737	HCT116	viability after 18 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	1.3364818372905738	[518]	[867,433,610]	8	hSpCas9	negative selection	2214955
63542225	63542248	20	-	26627737	HCT116	viability after 18 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	0.5872222540109739	[143]	[90,150,66]	5	hSpCas9	negative selection	2214956
63542518	63542541	20	-	26627737	HCT116	viability after 18 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	0.7065293390277663	[48]	[69,16,29]	6	hSpCas9	negative selection	2214957
63544332	63544355	20	-	26627737	HCT116	viability after 18 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.34148016389090885	[1034]	[775,472,664]	3	hSpCas9	negative selection	2214958
63547397	63547420	20	-	26627737	HCT116	viability after 18 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.09095233240812611	[402]	[368,78,103]	-1	hSpCas9	negative selection	2214959
63547285	63547308	20	+	24336569	HL60	viability	TAGAGCGCAAGGAAGAGCTGAGG	SRMS	ENSG00000125508	-0.0075750146093326864	[646]	[1361]	0	hSpCas9	negative selection	2297283
63547290	63547313	20	+	24336569	HL60	viability	CGCAAGGAAGAGCTGAGGGAAGG	SRMS	ENSG00000125508	-0.04739651906674025	[836]	[1713]	0	hSpCas9	negative selection	2297284
63547335	63547358	20	+	24336569	HL60	viability	CGTGGGCACTGGGTCAGTGTTGG	SRMS	ENSG00000125508	-0.3027126606242412	[1680]	[2883]	-3	hSpCas9	negative selection	2297285
63547393	63547416	20	-	24336569	HL60	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	0.22948823940296081	[949]	[2356]	2	hSpCas9	negative selection	2297286
63547400	63547423	20	-	24336569	HL60	viability	CTTCTGGGACAAGATCTGGCCGG	SRMS	ENSG00000125508	0.08846090081341607	[795]	[1790]	0	hSpCas9	negative selection	2297287
63547409	63547432	20	+	24336569	HL60	viability	TCTTGTCCCAGAAGAAGGACAGG	SRMS	ENSG00000125508	-0.4692941324153428	[962]	[1471]	-4	hSpCas9	negative selection	2297288
63547415	63547438	20	-	24336569	HL60	viability	GGCCTTCCTGTCCTTCTTCTGGG	SRMS	ENSG00000125508	0.9465789365529068	[241]	[986]	7	hSpCas9	negative selection	2297289
63547430	63547453	20	+	24336569	HL60	viability	GGAAGGCCAGCCGCCTCCTGAGG	SRMS	ENSG00000125508	0.6416324941418985	[1316]	[4347]	5	hSpCas9	negative selection	2297290
63547435	63547458	20	+	24336569	HL60	viability	GCCAGCCGCCTCCTGAGGAACGG	SRMS	ENSG00000125508	-0.3087846054621963	[390]	[667]	-3	hSpCas9	negative selection	2297291
63547440	63547463	20	-	24336569	HL60	viability	TGGAGCCGTTCCTCAGGAGGCGG	SRMS	ENSG00000125508	0.44482249276465236	[643]	[1854]	4	hSpCas9	negative selection	2297292
63547285	63547308	20	+	24336569	KBM7	viability	TAGAGCGCAAGGAAGAGCTGAGG	SRMS	ENSG00000125508	0.3923326993308898	[506]	[1814]	3	hSpCas9	negative selection	2364460
63547290	63547313	20	+	24336569	KBM7	viability	CGCAAGGAAGAGCTGAGGGAAGG	SRMS	ENSG00000125508	-0.09372061277007937	[848]	[2169]	-1	hSpCas9	negative selection	2364461
63547335	63547358	20	+	24336569	KBM7	viability	CGTGGGCACTGGGTCAGTGTTGG	SRMS	ENSG00000125508	-0.15552589724355115	[1131]	[2771]	-1	hSpCas9	negative selection	2364462
63547393	63547416	20	-	24336569	KBM7	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	0.5456280860276934	[957]	[3813]	5	hSpCas9	negative selection	2364463
63547400	63547423	20	-	24336569	KBM7	viability	CTTCTGGGACAAGATCTGGCCGG	SRMS	ENSG00000125508	0.3763380789518833	[630]	[2233]	3	hSpCas9	negative selection	2364464
63547409	63547432	20	+	24336569	KBM7	viability	TCTTGTCCCAGAAGAAGGACAGG	SRMS	ENSG00000125508	-0.25931946013158036	[555]	[1266]	-2	hSpCas9	negative selection	2364465
63547415	63547438	20	-	24336569	KBM7	viability	GGCCTTCCTGTCCTTCTTCTGGG	SRMS	ENSG00000125508	0.676632830848662	[113]	[496]	6	hSpCas9	negative selection	2364466
63547430	63547453	20	+	24336569	KBM7	viability	GGAAGGCCAGCCGCCTCCTGAGG	SRMS	ENSG00000125508	0.46169897931642545	[1287]	[4837]	4	hSpCas9	negative selection	2364467
63547435	63547458	20	+	24336569	KBM7	viability	GCCAGCCGCCTCCTGAGGAACGG	SRMS	ENSG00000125508	-0.2642336793442486	[427]	[971]	-2	hSpCas9	negative selection	2364468
63547440	63547463	20	-	24336569	KBM7	viability	TGGAGCCGTTCCTCAGGAGGCGG	SRMS	ENSG00000125508	0.6636882278609212	[395]	[1710]	6	hSpCas9	negative selection	2364469
63544270	63544293	20	+	27013184	SW480	treatment with recombinant TRAIL	GAGGAAGGCCCCTGGTTCGTTGG	SRMS	ENSG00000125508	0.19232376646261223	[326,158]	[35,247]	1	hSpCas9	positive selection	2959246
63547087	63547110	20	+	27013184	SW480	treatment with recombinant TRAIL	CTCCGAGGCCGAGGTACTCACGG	SRMS	ENSG00000125508	0.5325785854493901	[178,301]	[116,188]	2	hSpCas9	positive selection	2959247
63544271	63544294	20	+	27013184	SW480	treatment with recombinant TRAIL	AGGAAGGCCCCTGGTTCGTTGGG	SRMS	ENSG00000125508	2.651734591428871	[193,260]	[508,750]	9	hSpCas9	positive selection	2959248
63547091	63547114	20	+	27013184	SW480	treatment with recombinant TRAIL	GAGGCCGAGGTACTCACGGTTGG	SRMS	ENSG00000125508	0.5694892198723713	[237,405]	[167,248]	3	hSpCas9	positive selection	2959249
63544333	63544356	20	-	27013184	SW480	treatment with recombinant TRAIL	TTTGCAGCTGGTACTTTAGCGGG	SRMS	ENSG00000125508	0.4407145616587811	[751,211]	[89,589]	2	hSpCas9	positive selection	2959250
63547404	63547427	20	+	27013184	SW480	treatment with recombinant TRAIL	CCAGATCTTGTCCCAGAAGAAGG	SRMS	ENSG00000125508	-0.006200682068100205	[382,473]	[169,199]	0	hSpCas9	positive selection	2959251
63544334	63544357	20	-	27013184	SW480	treatment with recombinant TRAIL	GTTTGCAGCTGGTACTTTAGCGG	SRMS	ENSG00000125508	1.891047915593874	[111,86]	[42,328]	8	hSpCas9	positive selection	2959253
63547409	63547432	20	+	27013184	SW480	treatment with recombinant TRAIL	TCTTGTCCCAGAAGAAGGACAGG	SRMS	ENSG00000125508	-1.1154229838905845	[1046,985]	[98,350]	-5	hSpCas9	positive selection	2959254
63544214	63544237	20	-	27013184	SW480	treatment with recombinant TRAIL	TCACTGTCAGGTACCTGGGGCGG	SRMS	ENSG00000125508	1.326582774565059	[103,251]	[154,228]	6	hSpCas9	positive selection	2959255
63547448	63547471	20	+	27013184	SW480	treatment with recombinant TRAIL	TGAGGAACGGCTCCATCCCCCGG	SRMS	ENSG00000125508	-0.2014201313884858	[117,130]	[29,69]	-1	hSpCas9	positive selection	2959256
63544217	63544240	20	-	27013184	SW480	treatment with recombinant TRAIL	TACTCACTGTCAGGTACCTGGGG	SRMS	ENSG00000125508	0.20131970217979056	[926,882]	[326,624]	1	hSpCas9	positive selection	2959257
63547462	63547485	20	+	27013184	SW480	treatment with recombinant TRAIL	ATCCCCCGGGGTCACCACGCTGG	SRMS	ENSG00000125508	1.6407900639515065	[416,581]	[892,333]	7	hSpCas9	positive selection	2959258
63544218	63544241	20	-	27013184	SW480	treatment with recombinant TRAIL	CTACTCACTGTCAGGTACCTGGG	SRMS	ENSG00000125508	0.0951889740258256	[277,172]	[115,91]	0	hSpCas9	positive selection	2959259
63544219	63544242	20	-	27013184	SW480	treatment with recombinant TRAIL	GCTACTCACTGTCAGGTACCTGG	SRMS	ENSG00000125508	-1.6521617147584682	[237,518]	[15,98]	-6	hSpCas9	positive selection	2959260
63544226	63544249	20	-	27013184	SW480	treatment with recombinant TRAIL	CTCGGGGGCTACTCACTGTCAGG	SRMS	ENSG00000125508	-0.3274424023916813	[484,492]	[146,197]	-1	hSpCas9	positive selection	2959262
63547108	63547131	20	+	27013184	SW480	treatment with recombinant TRAIL	GGTTGGTCTGAGAGCGTCTCAGG	SRMS	ENSG00000125508	0.8795608135318612	[72,253]	[115,133]	4	hSpCas9	positive selection	2959263
63544227	63544250	20	+	27013184	SW480	treatment with recombinant TRAIL	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.27203376910304067	[331,441]	[175,231]	1	hSpCas9	positive selection	2959264
63547127	63547150	20	+	27013184	SW480	treatment with recombinant TRAIL	CAGGAGAAGCCTTGGCCACGTGG	SRMS	ENSG00000125508	1.2694668556579598	[404,512]	[455,495]	6	hSpCas9	positive selection	2959265
63544255	63544278	20	+	27013184	SW480	treatment with recombinant TRAIL	CTCGCTGGGCCGGATGAGGAAGG	SRMS	ENSG00000125508	-1.321213289799099	[135,104]	[25,13]	-6	hSpCas9	positive selection	2959268
63547128	63547151	20	+	27013184	SW480	treatment with recombinant TRAIL	AGGAGAAGCCTTGGCCACGTGGG	SRMS	ENSG00000125508	0.15214590172184184	[258,573]	[211,165]	0	hSpCas9	positive selection	2959269
63544264	63544287	20	-	27013184	SW480	treatment with recombinant TRAIL	AACCAGGGGCCTTCCTCATCCGG	SRMS	ENSG00000125508	-1.9218123030230005	[437,572]	[53,60]	-7	hSpCas9	positive selection	2959270
63544317	63544340	20	-	27013184	SW480	treatment with recombinant TRAIL	TAGCGGGGTCAGTCGGACCCAGG	SRMS	ENSG00000125508	-0.22260928051241047	[25,53]	[22,1]	-1	hSpCas9	positive selection	2959271
63547146	63547169	20	+	27013184	SW480	treatment with recombinant TRAIL	GTGGGTGATGGGCACGAGCCCGG	SRMS	ENSG00000125508	1.3283862890469798	[54,36]	[20,92]	6	hSpCas9	positive selection	2959272
63544324	63544347	20	-	27013184	SW480	treatment with recombinant TRAIL	GGTACTTTAGCGGGGTCAGTCGG	SRMS	ENSG00000125508	1.532258284168542	[102,63]	[145,49]	7	hSpCas9	positive selection	2959273
63547274	63547297	20	+	27013184	SW480	treatment with recombinant TRAIL	CCGTGAAGTCATAGAGCGCAAGG	SRMS	ENSG00000125508	1.4476076251275265	[133,93]	[42,268]	6	hSpCas9	positive selection	2959274
63544332	63544355	20	-	27013184	SW480	treatment with recombinant TRAIL	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.07994670717011454	[811,745]	[380,321]	0	hSpCas9	positive selection	2959275
63547142	63547165	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCGTGCCCATCACCCACGTGG	SRMS	ENSG00000125508	0.16568775237962113	[2,2]	[3,1]	3	hSpCas9	positive selection	3023715
63547238	63547261	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGCTGAGTGTCCGCCGCGGGG	SRMS	ENSG00000125508	-0.8205923044980221	[2,2]	[1,0]	-8	hSpCas9	positive selection	3023716
63547354	63547377	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGGGGTCCAGGGACCCGGGGG	SRMS	ENSG00000125508	-1.1899803364109565	[4,3]	[1,0]	-9	hSpCas9	positive selection	3023717
63544332	63544355	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.21098980359574263	[2,2]	[3,2]	4	hSpCas9	positive selection	3023718
63547142	63547165	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCGTGCCCATCACCCACGTGG	SRMS	ENSG00000125508	-0.36654316579407104	[2,2]	[1,0]	-5	hSpCas9	positive selection	3091573
63547238	63547261	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGCTGAGTGTCCGCCGCGGGG	SRMS	ENSG00000125508	0.51339304896255	[2,2]	[2,2]	8	hSpCas9	positive selection	3091574
63547354	63547377	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGGGGTCCAGGGACCCGGGGG	SRMS	ENSG00000125508	-0.8118583353998415	[4,4]	[2,0]	-9	hSpCas9	positive selection	3091575
63544332	63544355	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.15710083857001508	[2,2]	[3,1]	2	hSpCas9	positive selection	3091576
63541212	63541235		+	24336571	A375	resistance to PLX after 7 days	AGGTGAAAACCTCGTGCAGCAGG	SRMS	ENSG00000125508	-0.20072795603555482	[3,6]	[4,3]	-6	hSpCas9	positive selection	3147456
63541486	63541509		+	24336571	A375	resistance to PLX after 7 days	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.2646625145911208	[22,22]	[25,28]	7	hSpCas9	positive selection	3147457
63541221	63541244		-	24336571	A375	resistance to PLX after 7 days	CTTCGGCGTCCTGCTGCACGAGG	SRMS	ENSG00000125508	-0.3253854915584081	[21,20]	[17,15]	-8	hSpCas9	positive selection	3147458
63541492	63541515		-	24336571	A375	resistance to PLX after 7 days	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	-0.28331186082333226	[10,8]	[6,8]	-8	hSpCas9	positive selection	3147459
63541212	63541235		+	24336571	A375	resistance to PLX after 14 days	AGGTGAAAACCTCGTGCAGCAGG	SRMS	ENSG00000125508	0.5940764418379777	[3,3]	[1,2]	5	hSpCas9	positive selection	3205249
63541486	63541509		+	24336571	A375	resistance to PLX after 14 days	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.34197965336448694	[16,20]	[7,5]	-4	hSpCas9	positive selection	3205250
63541221	63541244		-	24336571	A375	resistance to PLX after 14 days	CTTCGGCGTCCTGCTGCACGAGG	SRMS	ENSG00000125508	-1.5465400610082043	[23,22]	[3,2]	-9	hSpCas9	positive selection	3205251
63541492	63541515		-	24336571	A375	resistance to PLX after 14 days	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	-0.47998346866927377	[17,5]	[2,3]	-6	hSpCas9	positive selection	3205252
63541212	63541235		+	24336571	A375	viability after 7 days	AGGTGAAAACCTCGTGCAGCAGG	SRMS	ENSG00000125508	0.6766430664472378	[2]	[3,6]	8	hSpCas9	negative selection	3263042
63541486	63541509		+	24336571	A375	viability after 7 days	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.5214166974760233	[16]	[22,22]	7	hSpCas9	negative selection	3263043
63541221	63541244		-	24336571	A375	viability after 7 days	CTTCGGCGTCCTGCTGCACGAGG	SRMS	ENSG00000125508	0.5597885406540071	[14]	[21,20]	8	hSpCas9	negative selection	3263044
63541492	63541515		-	24336571	A375	viability after 7 days	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.6434088239072687	[6]	[10,8]	8	hSpCas9	negative selection	3263045
63541212	63541235		+	24336571	A375	viability after 14 days	AGGTGAAAACCTCGTGCAGCAGG	SRMS	ENSG00000125508	0.35533277529490226	[2]	[3,3]	4	hSpCas9	negative selection	3320835
63541486	63541509		+	24336571	A375	viability after 14 days	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.2665227382884338	[16]	[16,20]	3	hSpCas9	negative selection	3320836
63541221	63541244		-	24336571	A375	viability after 14 days	CTTCGGCGTCCTGCTGCACGAGG	SRMS	ENSG00000125508	0.701717435058882	[14]	[23,22]	8	hSpCas9	negative selection	3320837
63541492	63541515		-	24336571	A375	viability after 14 days	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.9092766700770224	[6]	[17,5]	9	hSpCas9	negative selection	3320838
63541492	63541515	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	1.2349583984173806	[64,64]	[0,0]	5	hSpCas9	positive selection	3394954
63544227	63544250	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.4908666381436253	[214,214]	[0,0]	-3	hSpCas9	positive selection	3394955
63547142	63547165	20	-	26780180	HT29	viability (Avana library 4 designs)	GCTCGTGCCCATCACCCACGTGG	SRMS	ENSG00000125508	0.937683080040869	[]	[]	3	hSpCas9	negative selection	3462384
63547238	63547261	20	-	26780180	HT29	viability (Avana library 4 designs)	GGAGCTGAGTGTCCGCCGCGGGG	SRMS	ENSG00000125508	0.964868213541246	[]	[]	4	hSpCas9	negative selection	3462385
63547353	63547376	20	+	26780180	HT29	viability (Avana library 4 designs)	GTTGGGGTCCAGGGACCCGGGGG	SRMS	ENSG00000125508	5.20900952255607	[]	[]	9	hSpCas9	negative selection	3462386
63544332	63544355	20	-	26780180	HT29	viability (Avana library 4 designs)	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.444212724100438	[]	[]	1	hSpCas9	negative selection	3462387
63547353	63547376	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGGGGTCCAGGGACCCGGGGG	SRMS	ENSG00000125508	0.124019140975921	[]	[]	0	hSpCas9	negative selection	3563911
63547142	63547165	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCGTGCCCATCACCCACGTGG	SRMS	ENSG00000125508	-6.86084952554064	[]	[]	-6	hSpCas9	negative selection	3563912
63547238	63547261	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGCTGAGTGTCCGCCGCGGGG	SRMS	ENSG00000125508	6.05765917216405	[]	[]	9	hSpCas9	negative selection	3563913
63544332	63544355	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.0545366764481219	[]	[]	0	hSpCas9	negative selection	3563914
63542570	63542593	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCCCTGCAGAAGGCCCCGAGG	SRMS	ENSG00000125508	4.90387002510429	[]	[]	8	hSpCas9	negative selection	3563915
63547353	63547376	20	+	26780180	A375	viability (Avana lentiGuide)	GTTGGGGTCCAGGGACCCGGGGG	SRMS	ENSG00000125508	17.1562480831482	[]	[]	8	hSpCas9	negative selection	3672570
63547142	63547165	20	-	26780180	A375	viability (Avana lentiGuide)	GCTCGTGCCCATCACCCACGTGG	SRMS	ENSG00000125508	2.03928894664674	[]	[]	2	hSpCas9	negative selection	3672571
63547238	63547261	20	-	26780180	A375	viability (Avana lentiGuide)	GGAGCTGAGTGTCCGCCGCGGGG	SRMS	ENSG00000125508	7.37727032262693	[]	[]	6	hSpCas9	negative selection	3672572
63544332	63544355	20	-	26780180	A375	viability (Avana lentiGuide)	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.741105120849156	[]	[]	0	hSpCas9	negative selection	3672573
63542570	63542593	20	-	26780180	A375	viability (Avana lentiGuide)	CCTCCCTGCAGAAGGCCCCGAGG	SRMS	ENSG00000125508	9.64364919572955	[]	[]	6	hSpCas9	negative selection	3672574
63547353	63547376	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGGGGTCCAGGGACCCGGGGG	SRMS	ENSG00000125508	-0.1172132608079011	[5]	[4,4]	-2	hSpCas9	positive selection	3781177
63547142	63547165	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCGTGCCCATCACCCACGTGG	SRMS	ENSG00000125508	-1.304643425790887	[3]	[0,0]	-9	hSpCas9	positive selection	3781178
63547238	63547261	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGCTGAGTGTCCGCCGCGGGG	SRMS	ENSG00000125508	0.02450394766040226	[3]	[4,2]	0	hSpCas9	positive selection	3781179
63544332	63544355	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.22494126561388197	[4]	[5,5]	6	hSpCas9	positive selection	3781180
63542570	63542593	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCCCTGCAGAAGGCCCCGAGG	SRMS	ENSG00000125508	0.16026934333509002	[4]	[4,4]	4	hSpCas9	positive selection	3781181
63547353	63547376	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGGGGTCCAGGGACCCGGGGG	SRMS	ENSG00000125508	-0.8567778506380509	[6]	[0,3]	-8	hSpCas9	positive selection	3889784
63547142	63547165	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCGTGCCCATCACCCACGTGG	SRMS	ENSG00000125508	-0.4739734907959785	[4]	[1,3]	-6	hSpCas9	positive selection	3889785
63547238	63547261	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGCTGAGTGTCCGCCGCGGGG	SRMS	ENSG00000125508	-0.14903025746717216	[4]	[4,1]	-2	hSpCas9	positive selection	3889786
63544332	63544355	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.2882072872279878	[4]	[5,3]	7	hSpCas9	positive selection	3889787
63542570	63542593	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCCCTGCAGAAGGCCCCGAGG	SRMS	ENSG00000125508	-0.40316805671008027	[5]	[2,3]	-5	hSpCas9	positive selection	3889788
63544274	63544297	20	+	26780180	A375	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	0.0506234391775587	[]	[]	0	hSpCas9	negative selection	3999491
63540909	63540932	20	+	26780180	A375	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	1.26797162448467	[]	[]	7	hSpCas9	negative selection	3999492
63540865	63540888	20	+	26780180	A375	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.898123035936452	[]	[]	4	hSpCas9	negative selection	3999493
63541486	63541509	20	+	26780180	A375	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	1.44982826013496	[]	[]	8	hSpCas9	negative selection	3999494
63544227	63544250	20	+	26780180	A375	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.974299573679472	[]	[]	4	hSpCas9	negative selection	3999495
63541492	63541515	20	-	26780180	A375	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.748160388071265	[]	[]	2	hSpCas9	negative selection	3999496
63544274	63544297	20	+	26780180	HT29	viability (GeCKOv2 library)	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	0.0788571339295289	[]	[]	0	hSpCas9	negative selection	4107457
63540909	63540932	20	+	26780180	HT29	viability (GeCKOv2 library)	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	2.62182334796356	[]	[]	9	hSpCas9	negative selection	4107458
63540865	63540888	20	+	26780180	HT29	viability (GeCKOv2 library)	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	1.28884306969832	[]	[]	6	hSpCas9	negative selection	4107459
63541486	63541509	20	+	26780180	HT29	viability (GeCKOv2 library)	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	1.53116556770596	[]	[]	7	hSpCas9	negative selection	4107460
63544227	63544250	20	+	26780180	HT29	viability (GeCKOv2 library)	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.0573559628901213	[]	[]	-2	hSpCas9	negative selection	4107461
63541492	63541515	20	-	26780180	HT29	viability (GeCKOv2 library)	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.341572901464531	[]	[]	0	hSpCas9	negative selection	4107462
63541212	63541235	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGTGAAAACCTCGTGCAGCAGG	SRMS	ENSG00000125508	0.18558361802000378	[1]	[1,1]	5	hSpCas9	positive selection	4173650
63541486	63541509	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.11777866637113574	[4]	[2,2]	-3	hSpCas9	positive selection	4173651
63541221	63541244	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCGGCGTCCTGCTGCACGAGG	SRMS	ENSG00000125508	-0.27092516446429943	[4]	[2,1]	-6	hSpCas9	positive selection	4173652
63541492	63541515	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.017924348968468964	[3]	[2,1]	0	hSpCas9	positive selection	4173653
63541212	63541235	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGTGAAAACCTCGTGCAGCAGG	SRMS	ENSG00000125508	1.0559721408705827	[0]	[0,0,0,0]	7	hSpCas9	positive selection	4237672
63541486	63541509	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.46389762764605746	[4]	[0,3,2,2]	3	hSpCas9	positive selection	4237673
63541221	63541244	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCGGCGTCCTGCTGCACGAGG	SRMS	ENSG00000125508	1.0245018870761573	[4]	[3,2,5,3]	7	hSpCas9	positive selection	4237674
63541492	63541515	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	-0.3297353262198395	[2]	[0,0,0,0]	-5	hSpCas9	positive selection	4237675
63540909	63540932	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.06611943018030586	[3]	[3,2]	-1	hSpCas9	positive selection	4300621
63540865	63540888	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.38619310469213364	[1]	[0,0]	-7	hSpCas9	positive selection	4300622
63541486	63541509	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.007367418967960615	[4]	[3,2]	0	hSpCas9	positive selection	4300623
63541492	63541515	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	-0.09643378870190078	[1]	[1,0]	-2	hSpCas9	positive selection	4364876
63544274	63544297	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	0.2725891090236312	[0]	[0,0]	5	hSpCas9	positive selection	4364877
63544227	63544250	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.21818997996810574	[3]	[2,0]	-4	hSpCas9	positive selection	4364878
63542529	63542551	20	-	27760321	OCIAML3	viability	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	0.06272270826049575	[882,634]	[479,787]	0	hSpCas9	negative selection	4443177
63544278	63544300	20	-	27760321	OCIAML3	viability	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	-0.009460057873934221	[497,371]	[272,415]	0	hSpCas9	negative selection	4443178
63547214	63547236	20	-	27760321	OCIAML3	viability	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	-0.5771007228062423	[574,578]	[303,302]	-5	hSpCas9	negative selection	4443179
63547264	63547286	20	-	27760321	OCIAML3	viability	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	0.369885910833488	[1111,1004]	[945,1228]	4	hSpCas9	negative selection	4443180
63542529	63542551	20	-	27760321	OCIAML2	viability	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	-0.03819637378717944	[882,634]	[480,737]	0	hSpCas9	negative selection	4526640
63544278	63544300	20	-	27760321	OCIAML2	viability	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	-0.1579085210717214	[497,371]	[272,364]	-2	hSpCas9	negative selection	4526641
63547214	63547236	20	-	27760321	OCIAML2	viability	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	-0.49490664346803614	[574,578]	[293,382]	-5	hSpCas9	negative selection	4526642
63547264	63547286	20	-	27760321	OCIAML2	viability	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	-0.055626660147222395	[1111,1004]	[691,995]	0	hSpCas9	negative selection	4526643
63542529	63542551	20	-	27760321	MV411	viability	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	0.3685105743755924	[882,634]	[492,860]	2	hSpCas9	negative selection	4610103
63544278	63544300	20	-	27760321	MV411	viability	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	1.3145756438897163	[497,371]	[768,615]	8	hSpCas9	negative selection	4610104
63547214	63547236	20	-	27760321	MV411	viability	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	0.43024781832285863	[574,578]	[629,341]	3	hSpCas9	negative selection	4610105
63547264	63547286	20	-	27760321	MV411	viability	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	0.11179274013834406	[1111,1004]	[429,1240]	0	hSpCas9	negative selection	4610106
63542529	63542551	20	-	27760321	HL60	viability	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	0.025862626472372807	[882,634]	[668,577]	0	hSpCas9	negative selection	4693566
63544278	63544300	20	-	27760321	HL60	viability	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	-0.024224108485350743	[497,371]	[409,278]	0	hSpCas9	negative selection	4693567
63547214	63547236	20	-	27760321	HL60	viability	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	-0.25829305665389585	[574,578]	[311,483]	-3	hSpCas9	negative selection	4693568
63547264	63547286	20	-	27760321	HL60	viability	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	0.0028539249415517887	[1111,1004]	[902,825]	0	hSpCas9	negative selection	4693569
63542529	63542551	20	-	27760321	HT1080	viability	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	0.35867754846134337	[634,495]	[338,233]	1	hSpCas9	negative selection	4777029
63544278	63544300	20	-	27760321	HT1080	viability	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	0.018436119429773523	[371,289]	[123,143]	0	hSpCas9	negative selection	4777030
63547214	63547236	20	-	27760321	HT1080	viability	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	-0.8019915156580206	[578,451]	[165,64]	-3	hSpCas9	negative selection	4777031
63547264	63547286	20	-	27760321	HT1080	viability	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	0.4680589548276839	[1004,783]	[574,402]	2	hSpCas9	negative selection	4777032
63542529	63542551	20	-	27760321	HT29	viability after 7 days	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	0.48330096641200604	[634,495]	[816,1171,1029]	7	hSpCas9	negative selection	4860492
63544278	63544300	20	-	27760321	HT29	viability after 7 days	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	0.6869973406610835	[371,289]	[598,884,561]	9	hSpCas9	negative selection	4860493
63547214	63547236	20	-	27760321	HT29	viability after 7 days	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	-0.30421562484553066	[578,451]	[696,416,518]	-4	hSpCas9	negative selection	4860494
63547264	63547286	20	-	27760321	HT29	viability after 7 days	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	-0.0731152074375998	[1004,783]	[1430,922,975]	-1	hSpCas9	negative selection	4860495
63542529	63542551	20	-	27760321	HT29	viability after 25 days	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	0.7185070478026245	[634,495]	[878,1140,1193]	7	hSpCas9	negative selection	4943955
63544278	63544300	20	-	27760321	HT29	viability after 25 days	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	1.0456239432955479	[371,289]	[576,901,885]	9	hSpCas9	negative selection	4943956
63547214	63547236	20	-	27760321	HT29	viability after 25 days	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	0.052500644785250405	[578,451]	[441,570,854]	0	hSpCas9	negative selection	4943957
63547264	63547286	20	-	27760321	HT29	viability after 25 days	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	0.46838486144915326	[1004,783]	[1464,1328,1446]	5	hSpCas9	negative selection	4943958
63542529	63542551	20	-	27760321	HT29	viability after 22 days	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	1.041979807875454	[634,495]	[1495,1023,1515]	9	hSpCas9	negative selection	5027418
63544278	63544300	20	-	27760321	HT29	viability after 22 days	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	0.9464361417083231	[371,289]	[670,788,753]	9	hSpCas9	negative selection	5027419
63547214	63547236	20	-	27760321	HT29	viability after 22 days	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	-0.31173864058178746	[578,451]	[540,496,399]	-3	hSpCas9	negative selection	5027420
63547264	63547286	20	-	27760321	HT29	viability after 22 days	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	0.27625244707642116	[1004,783]	[1331,1134,1287]	3	hSpCas9	negative selection	5027421
63542529	63542551	20	-	27760321	HT29	viability after 19 days	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	0.6726927237637235	[634,495]	[978,919,1181]	6	hSpCas9	negative selection	5110881
63544278	63544300	20	-	27760321	HT29	viability after 19 days	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	0.8238992831490609	[371,289]	[441,903,640]	8	hSpCas9	negative selection	5110882
63547214	63547236	20	-	27760321	HT29	viability after 19 days	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	0.1652178082957687	[578,451]	[760,722,514]	1	hSpCas9	negative selection	5110883
63547264	63547286	20	-	27760321	HT29	viability after 19 days	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	0.3370675834052004	[1004,783]	[1178,884,1780]	3	hSpCas9	negative selection	5110884
63542529	63542551	20	-	27760321	HT29	viability after 16 days	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	0.6624480886623505	[634,495]	[998,883,1123]	7	hSpCas9	negative selection	5194344
63544278	63544300	20	-	27760321	HT29	viability after 16 days	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	0.7835496991543448	[371,289]	[500,723,671]	8	hSpCas9	negative selection	5194345
63547214	63547236	20	-	27760321	HT29	viability after 16 days	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	-0.08053763915205364	[578,451]	[680,584,381]	-1	hSpCas9	negative selection	5194346
63547264	63547286	20	-	27760321	HT29	viability after 16 days	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	0.12219018877327592	[1004,783]	[1059,1113,1089]	1	hSpCas9	negative selection	5194347
63542529	63542551	20	-	27760321	HT29	viability after 13 days	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	0.41055336371713946	[634,495]	[887,924,806]	5	hSpCas9	negative selection	5277807
63544278	63544300	20	-	27760321	HT29	viability after 13 days	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	0.8453947532487748	[371,289]	[544,955,575]	9	hSpCas9	negative selection	5277808
63547214	63547236	20	-	27760321	HT29	viability after 13 days	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	-0.04240837130175362	[578,451]	[466,603,665]	0	hSpCas9	negative selection	5277809
63547264	63547286	20	-	27760321	HT29	viability after 13 days	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	0.09355608919734393	[1004,783]	[1281,999,1042]	1	hSpCas9	negative selection	5277810
63542529	63542551	20	-	27760321	HT29	viability after 10 days	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	0.5704004899596968	[634,495]	[892,1431,835]	7	hSpCas9	negative selection	5361270
63544278	63544300	20	-	27760321	HT29	viability after 10 days	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	0.7858356344872128	[371,289]	[578,1006,562]	9	hSpCas9	negative selection	5361271
63547214	63547236	20	-	27760321	HT29	viability after 10 days	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	-0.07448784405297154	[578,451]	[538,870,434]	-1	hSpCas9	negative selection	5361272
63547264	63547286	20	-	27760321	HT29	viability after 10 days	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	-0.10465873831556727	[1004,783]	[1168,683,1247]	-1	hSpCas9	negative selection	5361273
63542529	63542551	20	-	27760321	MOLM13	viability	CACACTCCGAATTCGCCCTTGG	SRMS	ENSG00000125508	0.7619408302190357	[882,634]	[801,647]	5	hSpCas9	negative selection	5444733
63544278	63544300	20	-	27760321	MOLM13	viability	TCCCCACCCAACGAACCAGGGG	SRMS	ENSG00000125508	0.49230128742400947	[497,371]	[526,184]	3	hSpCas9	negative selection	5444734
63547214	63547236	20	-	27760321	MOLM13	viability	AGGCTCTGTGCCCTCGAAGAGG	SRMS	ENSG00000125508	-0.46092608886771463	[574,578]	[319,166]	-3	hSpCas9	negative selection	5444735
63547264	63547286	20	-	27760321	MOLM13	viability	ATGACTTCACGGCGCGGTGTGG	SRMS	ENSG00000125508	1.5442845120999666	[1111,1004]	[2872,775]	9	hSpCas9	negative selection	5444736
63547464	63547487	20	-	27661255	K562	viability	GCCCAGCGTGGTGACCCCGGGGG	SRMS	ENSG00000125508	0.042693422182478624	[290,322]	[236,264]	1	dCas9-KRAB	negative selection	5514287
63540909	63540932	20	+	27260156	BXPC3	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.5509062298481708	[908]	[644,516,717,729]	-8	hSpCas9	negative selection	5573081
63540865	63540888	20	+	27260156	BXPC3	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.14625360739967497	[188]	[227,163,259,224]	3	hSpCas9	negative selection	5573082
63541486	63541509	20	+	27260156	BXPC3	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.3965608413760633	[999]	[783,793,698,907]	-7	hSpCas9	negative selection	5573083
63541492	63541515	20	-	27260156	BXPC3	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.22535907956136314	[112]	[153,145,75,176]	5	hSpCas9	negative selection	5637336
63544274	63544297	20	+	27260156	BXPC3	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	0.4735028948442954	[3]	[6,0,12,1]	8	hSpCas9	negative selection	5637337
63544227	63544250	20	+	27260156	BXPC3	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.030017168958189233	[476]	[406,393,500,687]	0	hSpCas9	negative selection	5637338
63540909	63540932	20	+	27260156	A673	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.37750566119968365	[908]	[1008,726,845,796]	-7	hSpCas9	negative selection	5694332
63540865	63540888	20	+	27260156	A673	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.03271511206791877	[188]	[242,270,164,250]	0	hSpCas9	negative selection	5694333
63541486	63541509	20	+	27260156	A673	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.09595957767777519	[999]	[1314,1062,974,1165]	-2	hSpCas9	negative selection	5694334
63541492	63541515	20	-	27260156	A673	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.3746659400049501	[112]	[189,221,134,155]	8	hSpCas9	negative selection	5758587
63544274	63544297	20	+	27260156	A673	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-2.2631622979798074	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	5758588
63544227	63544250	20	+	27260156	A673	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.03879029866518792	[476]	[627,538,485,586]	-1	hSpCas9	negative selection	5758589
63540909	63540932	20	+	27260156	A375	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.2289857871054788	[908]	[931,1133,911,698]	-3	hSpCas9	negative selection	5815583
63540865	63540888	20	+	27260156	A375	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.6801574881302694	[188]	[92,186,147,129]	-7	hSpCas9	negative selection	5815584
63541486	63541509	20	+	27260156	A375	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.0012751928216654385	[999]	[1301,1296,977,1111]	0	hSpCas9	negative selection	5815585
63541492	63541515	20	-	27260156	A375	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.015246018798757088	[112]	[122,136,98,169]	0	hSpCas9	negative selection	5879838
63544274	63544297	20	+	27260156	A375	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-0.7935864033938911	[3]	[0,0,0,6]	-7	hSpCas9	negative selection	5879839
63544227	63544250	20	+	27260156	A375	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.09481744600132617	[476]	[430,713,708,544]	1	hSpCas9	negative selection	5879840
63540909	63540932	20	+	27260156	COLO741	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.25883064483235096	[908]	[1079,938,904]	-5	hSpCas9	negative selection	5936834
63540865	63540888	20	+	27260156	COLO741	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.21013662905229302	[188]	[357,166,119]	-4	hSpCas9	negative selection	5936835
63541486	63541509	20	+	27260156	COLO741	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.03334535221111956	[999]	[1437,1316,1020]	0	hSpCas9	negative selection	5936836
63541492	63541515	20	-	27260156	COLO741	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	-0.29549409321321907	[112]	[95,152,102]	-6	hSpCas9	negative selection	6001089
63544274	63544297	20	+	27260156	COLO741	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-1.296399875992476	[3]	[0,0,3]	-9	hSpCas9	negative selection	6001090
63544227	63544250	20	+	27260156	COLO741	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.13899532081840496	[476]	[559,479,614]	-3	hSpCas9	negative selection	6001091
63540909	63540932	20	+	27260156	CAL120	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.4122166581485548	[908]	[973,723,869]	-5	hSpCas9	negative selection	6058085
63540865	63540888	20	+	27260156	CAL120	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.045227422601804346	[188]	[191,297,188]	0	hSpCas9	negative selection	6058086
63541486	63541509	20	+	27260156	CAL120	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.10703675238311772	[999]	[1834,1167,1095]	1	hSpCas9	negative selection	6058087
63541492	63541515	20	-	27260156	CAL120	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	-0.07489349402538359	[112]	[258,119,41]	-1	hSpCas9	negative selection	6122340
63544274	63544297	20	+	27260156	CAL120	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-2.3152262340772953	[3]	[0,0,0]	-9	hSpCas9	negative selection	6122341
63544227	63544250	20	+	27260156	CAL120	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.5532177281939621	[476]	[936,617,1063]	7	hSpCas9	negative selection	6122342
63540909	63540932	20	+	27260156	CADOES1	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.5166173532741898	[908]	[479,707,619,554]	-7	hSpCas9	negative selection	6179336
63540865	63540888	20	+	27260156	CADOES1	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.058147669782791844	[188]	[161,204,150,156]	-1	hSpCas9	negative selection	6179337
63541486	63541509	20	+	27260156	CADOES1	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.008369103425892366	[999]	[809,924,896,1116]	0	hSpCas9	negative selection	6179338
63541492	63541515	20	-	27260156	CADOES1	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.6459973358536473	[112]	[51,164,227,214]	9	hSpCas9	negative selection	6243591
63544274	63544297	20	+	27260156	CADOES1	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-0.8885331983254972	[3]	[0,0,4,0]	-9	hSpCas9	negative selection	6243592
63544227	63544250	20	+	27260156	CADOES1	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.2303870130701166	[476]	[288,456,414,350]	-4	hSpCas9	negative selection	6243593
63540909	63540932	20	+	27260156	EWS502	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.48946600091997183	[908]	[634,646,597,880]	-7	hSpCas9	negative selection	6300587
63540865	63540888	20	+	27260156	EWS502	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.3560342009112717	[188]	[147,294,297,297]	6	hSpCas9	negative selection	6300588
63541486	63541509	20	+	27260156	EWS502	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.15965748996037166	[999]	[798,1086,949,966]	-3	hSpCas9	negative selection	6300589
63541492	63541515	20	-	27260156	EWS502	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.43275073783178075	[112]	[215,94,149,181]	7	hSpCas9	negative selection	6364842
63544274	63544297	20	+	27260156	EWS502	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-2.081568668955347	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	6364843
63544227	63544250	20	+	27260156	EWS502	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.1518638634539647	[476]	[453,492,809,500]	2	hSpCas9	negative selection	6364844
63540909	63540932	20	+	27260156	EW8	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.4414431252498441	[908]	[558,570,340,732]	-7	hSpCas9	negative selection	6421838
63540865	63540888	20	+	27260156	EW8	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.3932214326283998	[188]	[183,110,90,91]	-6	hSpCas9	negative selection	6421839
63541486	63541509	20	+	27260156	EW8	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.12686466982034883	[999]	[783,953,873,915]	2	hSpCas9	negative selection	6421840
63541492	63541515	20	-	27260156	EW8	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.07060573349018306	[112]	[116,59,86,123]	1	hSpCas9	negative selection	6486093
63544274	63544297	20	+	27260156	EW8	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	1.4467339146247582	[3]	[4,26,2,0]	9	hSpCas9	negative selection	6486094
63544227	63544250	20	+	27260156	EW8	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.05101399374289607	[476]	[438,354,332,488]	0	hSpCas9	negative selection	6486095
63540909	63540932	20	+	27260156	CORL105	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.22926342309007375	[908]	[855,799,1016,974]	-4	hSpCas9	negative selection	6543089
63540865	63540888	20	+	27260156	CORL105	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.10508344987549822	[188]	[186,285,180,285]	2	hSpCas9	negative selection	6543090
63541486	63541509	20	+	27260156	CORL105	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.09720821758628251	[999]	[1356,1053,1659,1009]	1	hSpCas9	negative selection	6543091
63541492	63541515	20	-	27260156	CORL105	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.0029389732734346197	[112]	[108,190,148,81]	0	hSpCas9	negative selection	6607344
63544274	63544297	20	+	27260156	CORL105	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-1.2073064598062828	[3]	[2,0,0,2]	-9	hSpCas9	negative selection	6607345
63544227	63544250	20	+	27260156	CORL105	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.12915419206998474	[476]	[458,608,449,510]	-2	hSpCas9	negative selection	6607346
63540909	63540932	20	+	27260156	HS294T	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	0.22048089536835047	[908]	[230,528,329,589]	3	hSpCas9	negative selection	6664340
63540865	63540888	20	+	27260156	HS294T	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.3667349253498846	[188]	[25,62,49,96]	-5	hSpCas9	negative selection	6664341
63541486	63541509	20	+	27260156	HS294T	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.20421722320057278	[999]	[427,582,396,353]	2	hSpCas9	negative selection	6664342
63541492	63541515	20	-	27260156	HS294T	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.037334256050341796	[112]	[75,25,33,39]	0	hSpCas9	negative selection	6728595
63544274	63544297	20	+	27260156	HS294T	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-0.2753613201393499	[3]	[1,0,0,0]	-4	hSpCas9	negative selection	6728596
63544227	63544250	20	+	27260156	HS294T	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.21807842103536335	[476]	[165,176,242,289]	3	hSpCas9	negative selection	6728597
63540909	63540932	20	+	27260156	HCC44	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.5819000387730987	[908]	[688,725,691,631]	-7	hSpCas9	negative selection	6785591
63540865	63540888	20	+	27260156	HCC44	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.6298753007167517	[188]	[149,143,181,84]	-7	hSpCas9	negative selection	6785592
63541486	63541509	20	+	27260156	HCC44	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.01324576276350009	[999]	[1484,968,1086,985]	0	hSpCas9	negative selection	6785593
63541492	63541515	20	-	27260156	HCC44	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.007227398622060566	[112]	[117,93,187,126]	0	hSpCas9	negative selection	6849846
63544274	63544297	20	+	27260156	HCC44	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-2.174533516205509	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	6849847
63544227	63544250	20	+	27260156	HCC44	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.5357537056876193	[476]	[433,214,403,462]	-7	hSpCas9	negative selection	6849848
63540909	63540932	20	+	27260156	G402	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.1529634238812546	[908]	[1230,1101,817,880]	-2	hSpCas9	negative selection	6906842
63540865	63540888	20	+	27260156	G402	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.8827599846888616	[188]	[114,82,174,122]	-8	hSpCas9	negative selection	6906843
63541486	63541509	20	+	27260156	G402	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.36069819205107523	[999]	[1444,1456,1680,1649]	4	hSpCas9	negative selection	6906844
63541492	63541515	20	-	27260156	G402	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	1.174110500263395	[112]	[420,259,131,436]	9	hSpCas9	negative selection	6971097
63544274	63544297	20	+	27260156	G402	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-2.285659902410133	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	6971098
63544227	63544250	20	+	27260156	G402	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.7398441727022346	[476]	[315,297,398,370]	-7	hSpCas9	negative selection	6971099
63540909	63540932	20	+	27260156	L33	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.19421471972684634	[908]	[815,327,509,749]	-4	hSpCas9	negative selection	7028093
63540865	63540888	20	+	27260156	L33	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.23072344187258342	[188]	[200,72,155,259]	5	hSpCas9	negative selection	7028094
63541486	63541509	20	+	27260156	L33	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.32281360791427305	[999]	[878,354,505,646]	-6	hSpCas9	negative selection	7028095
63541492	63541515	20	-	27260156	L33	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	-0.20904144260283308	[112]	[120,29,55,106]	-5	hSpCas9	negative selection	7092348
63544274	63544297	20	+	27260156	L33	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-1.4116667406927963	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	7092349
63544227	63544250	20	+	27260156	L33	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.11359904740014633	[476]	[445,242,352,465]	2	hSpCas9	negative selection	7092350
63540909	63540932	20	+	27260156	K562	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	0.13781172263384966	[908]	[875,983,977,730]	1	hSpCas9	negative selection	7149344
63540865	63540888	20	+	27260156	K562	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.51401053584092	[188]	[273,229,221,233]	6	hSpCas9	negative selection	7149345
63541486	63541509	20	+	27260156	K562	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.08375625980926338	[999]	[1037,703,915,1078]	1	hSpCas9	negative selection	7149346
63541492	63541515	20	-	27260156	K562	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	-0.045477581946740564	[112]	[167,99,45,81]	0	hSpCas9	negative selection	7213599
63544274	63544297	20	+	27260156	K562	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-1.8261501679237142	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	7213600
63544227	63544250	20	+	27260156	K562	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.16571423702314092	[476]	[239,325,456,460]	-2	hSpCas9	negative selection	7213601
63540909	63540932	20	+	27260156	HT29	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.5202164842266098	[908]	[886,839,627,739]	-7	hSpCas9	negative selection	7270595
63540865	63540888	20	+	27260156	HT29	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.13255086949225503	[188]	[247,285,309,173]	2	hSpCas9	negative selection	7270596
63541486	63541509	20	+	27260156	HT29	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.12474621051500612	[999]	[961,1111,1218,1142]	-3	hSpCas9	negative selection	7270597
63541492	63541515	20	-	27260156	HT29	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.33032199344138014	[112]	[183,199,164,146]	6	hSpCas9	negative selection	7334850
63544274	63544297	20	+	27260156	HT29	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-0.41505485205857884	[3]	[7,0,4,0]	-6	hSpCas9	negative selection	7334851
63544227	63544250	20	+	27260156	HT29	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.2378423328102604	[476]	[605,425,429,502]	-5	hSpCas9	negative selection	7334852
63540909	63540932	20	+	27260156	MHHES1	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.05517857266982773	[908]	[1003,1290,969,743]	-1	hSpCas9	negative selection	7391846
63540865	63540888	20	+	27260156	MHHES1	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.0919782448476758	[188]	[152,249,283,124]	-2	hSpCas9	negative selection	7391847
63541486	63541509	20	+	27260156	MHHES1	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.1704477952718877	[999]	[983,1054,817,1100]	-3	hSpCas9	negative selection	7391848
63541492	63541515	20	-	27260156	MHHES1	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.4904857509646201	[112]	[115,98,250,219]	8	hSpCas9	negative selection	7456101
63544274	63544297	20	+	27260156	MHHES1	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-2.1630968580950416	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	7456102
63544227	63544250	20	+	27260156	MHHES1	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.09594626544340085	[476]	[769,448,597,495]	1	hSpCas9	negative selection	7456103
63540909	63540932	20	+	27260156	MEWO	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.5033758698393033	[908]	[500,703,574]	-8	hSpCas9	negative selection	7513097
63540865	63540888	20	+	27260156	MEWO	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.1356413623794135	[188]	[115,184,172]	-3	hSpCas9	negative selection	7513098
63541486	63541509	20	+	27260156	MEWO	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.043027515258289295	[999]	[962,1041,728]	-1	hSpCas9	negative selection	7513099
63541492	63541515	20	-	27260156	MEWO	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.20405767627386262	[112]	[93,107,157]	4	hSpCas9	negative selection	7577352
63544274	63544297	20	+	27260156	MEWO	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	0.047833248216658575	[3]	[10,0,0]	1	hSpCas9	negative selection	7577353
63544227	63544250	20	+	27260156	MEWO	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.05786149174064563	[476]	[633,321,470]	1	hSpCas9	negative selection	7577354
63540909	63540932	20	+	27260156	LNCAPCLONEFGC	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.4881314462985392	[908]	[629,567,490,644]	-6	hSpCas9	negative selection	7634348
63540865	63540888	20	+	27260156	LNCAPCLONEFGC	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.15255538403117463	[188]	[129,159,166,160]	-2	hSpCas9	negative selection	7634349
63541486	63541509	20	+	27260156	LNCAPCLONEFGC	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.1895287881476495	[999]	[641,796,1005,765]	-3	hSpCas9	negative selection	7634350
63541492	63541515	20	-	27260156	LNCAPCLONEFGC	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.2295879455167109	[112]	[88,156,118,112]	3	hSpCas9	negative selection	7698603
63544274	63544297	20	+	27260156	LNCAPCLONEFGC	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-1.8571017168614112	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	7698604
63544227	63544250	20	+	27260156	LNCAPCLONEFGC	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.1395066324647925	[476]	[267,526,369,393]	-2	hSpCas9	negative selection	7698605
63540909	63540932	20	+	27260156	PANC0327	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.46885786076294933	[908]	[620,503,653,567]	-6	hSpCas9	negative selection	7755599
63540865	63540888	20	+	27260156	PANC0327	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.1058953770683344	[188]	[88,221,163,134]	-1	hSpCas9	negative selection	7755600
63541486	63541509	20	+	27260156	PANC0327	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.040836908205681643	[999]	[970,607,661,1253]	0	hSpCas9	negative selection	7755601
63541492	63541515	20	-	27260156	PANC0327	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.42331161590111477	[112]	[158,59,141,188]	6	hSpCas9	negative selection	7819854
63544274	63544297	20	+	27260156	PANC0327	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-1.8290241986648574	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	7819855
63544227	63544250	20	+	27260156	PANC0327	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.24427876380213215	[476]	[588,487,320,617]	3	hSpCas9	negative selection	7819856
63540909	63540932	20	+	27260156	NCIH2009	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	0.138699911155589	[908]	[1549,1296,1376]	2	hSpCas9	negative selection	7876850
63540865	63540888	20	+	27260156	NCIH2009	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.17819840945526844	[188]	[274,360,253]	2	hSpCas9	negative selection	7876851
63541486	63541509	20	+	27260156	NCIH2009	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.2589457597297036	[999]	[1831,1690,1520]	3	hSpCas9	negative selection	7876852
63541492	63541515	20	-	27260156	NCIH2009	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.8190446653864862	[112]	[587,184,124]	9	hSpCas9	negative selection	7941105
63544274	63544297	20	+	27260156	NCIH2009	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-2.481625123746422	[3]	[0,0,0]	-9	hSpCas9	negative selection	7941106
63544227	63544250	20	+	27260156	NCIH2009	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.029244295456353056	[476]	[759,509,787]	0	hSpCas9	negative selection	7941107
63540909	63540932	20	+	27260156	NCIH1373	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	0.526542476611458	[908]	[1754,1854,1293,244]	5	hSpCas9	negative selection	7998101
63540865	63540888	20	+	27260156	NCIH1373	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.1047357983413586	[188]	[197,316,105,39]	-1	hSpCas9	negative selection	7998102
63541486	63541509	20	+	27260156	NCIH1373	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.39225114438787845	[999]	[1325,1837,1042,426]	4	hSpCas9	negative selection	7998103
63541492	63541515	20	-	27260156	NCIH1373	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.14961743494981228	[112]	[209,140,140,19]	1	hSpCas9	negative selection	8062356
63544274	63544297	20	+	27260156	NCIH1373	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-1.4198903640528862	[3]	[0,0,0,0]	-8	hSpCas9	negative selection	8062357
63544227	63544250	20	+	27260156	NCIH1373	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.09837713751121434	[476]	[823,583,245,99]	-1	hSpCas9	negative selection	8062358
63540909	63540932	20	+	27260156	PATU8902	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	0.06787943751245062	[908]	[674,1887,1249,1539]	0	hSpCas9	negative selection	8119352
63540865	63540888	20	+	27260156	PATU8902	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.08298553775968487	[188]	[182,240,191,410]	-1	hSpCas9	negative selection	8119353
63541486	63541509	20	+	27260156	PATU8902	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.2243494542722353	[999]	[1651,980,760,1507]	-2	hSpCas9	negative selection	8119354
63541492	63541515	20	-	27260156	PATU8902	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	1.0276007825146452	[112]	[400,337,132,474]	9	hSpCas9	negative selection	8183607
63544274	63544297	20	+	27260156	PATU8902	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-0.41100871834965425	[3]	[0,0,0,15]	-4	hSpCas9	negative selection	8183608
63544227	63544250	20	+	27260156	PATU8902	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.23640541545378402	[476]	[535,1162,601,886]	2	hSpCas9	negative selection	8183609
63540909	63540932	20	+	27260156	PANC1	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.7676767059269056	[908]	[657,651,381,210]	-8	hSpCas9	negative selection	8240603
63540865	63540888	20	+	27260156	PANC1	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.4149127659098011	[188]	[233,392,121,157]	6	hSpCas9	negative selection	8240604
63541486	63541509	20	+	27260156	PANC1	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.23511577421241914	[999]	[624,826,726,746]	-4	hSpCas9	negative selection	8240605
63541492	63541515	20	-	27260156	PANC1	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.18213289633577268	[112]	[89,62,180,97]	3	hSpCas9	negative selection	8304858
63544274	63544297	20	+	27260156	PANC1	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	1.4574889041076773	[3]	[2,0,21,9]	9	hSpCas9	negative selection	8304859
63544227	63544250	20	+	27260156	PANC1	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.0319994518961379	[476]	[428,494,318,436]	0	hSpCas9	negative selection	8304860
63540909	63540932	20	+	27260156	PANC0813	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.19349942802927822	[908]	[857,999,1014,857]	-3	hSpCas9	negative selection	8361854
63540865	63540888	20	+	27260156	PANC0813	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.2589812919600858	[188]	[193,223,215,412]	4	hSpCas9	negative selection	8361855
63541486	63541509	20	+	27260156	PANC0813	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.08892000493501784	[999]	[1127,1383,895,1013]	-1	hSpCas9	negative selection	8361856
63541492	63541515	20	-	27260156	PANC0813	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.44731497412783927	[112]	[110,48,167,377]	7	hSpCas9	negative selection	8426109
63544274	63544297	20	+	27260156	PANC0813	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-2.23161252818376	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	8426110
63544227	63544250	20	+	27260156	PANC0813	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.3318889157837914	[476]	[728,747,628,714]	5	hSpCas9	negative selection	8426111
63540909	63540932	20	+	27260156	RDES	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.2873220604615536	[908]	[867,654,847,1076]	-5	hSpCas9	negative selection	8483105
63540865	63540888	20	+	27260156	RDES	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.18562422770796005	[188]	[134,150,166,344]	-3	hSpCas9	negative selection	8483106
63541486	63541509	20	+	27260156	RDES	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.16942851870669084	[999]	[1038,1263,1303,1637]	2	hSpCas9	negative selection	8483107
63541492	63541515	20	-	27260156	RDES	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.409031376844331	[112]	[131,181,164,220]	6	hSpCas9	negative selection	8547360
63544274	63544297	20	+	27260156	RDES	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-2.1894203535537233	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	8547361
63544227	63544250	20	+	27260156	RDES	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.3234217179761984	[476]	[316,410,503,558]	-5	hSpCas9	negative selection	8547362
63540909	63540932	20	+	27260156	PC3	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.3913142926254547	[908]	[376,766,1332,605]	-7	hSpCas9	negative selection	8604356
63540865	63540888	20	+	27260156	PC3	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.13873200491477022	[188]	[166,178,200,276]	3	hSpCas9	negative selection	8604357
63541486	63541509	20	+	27260156	PC3	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.10478659555565184	[999]	[608,720,1623,1090]	-2	hSpCas9	negative selection	8604358
63541492	63541515	20	-	27260156	PC3	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	-0.1731557042635985	[112]	[95,109,148,47]	-4	hSpCas9	negative selection	8668611
63544274	63544297	20	+	27260156	PC3	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	0.07111736006671787	[3]	[0,12,0,0]	1	hSpCas9	negative selection	8668612
63544227	63544250	20	+	27260156	PC3	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.12748248778658827	[476]	[462,471,388,665]	3	hSpCas9	negative selection	8668613
63540909	63540932	20	+	27260156	PATU8988T	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.3558657409465267	[908]	[1000,654,533,542]	-5	hSpCas9	negative selection	8725607
63540865	63540888	20	+	27260156	PATU8988T	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.27488898637161063	[188]	[80,138,225,155]	-5	hSpCas9	negative selection	8725608
63541486	63541509	20	+	27260156	PATU8988T	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.09740770917626373	[999]	[781,1192,760,905]	-2	hSpCas9	negative selection	8725609
63541492	63541515	20	-	27260156	PATU8988T	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.6581876433645939	[112]	[174,134,293,71]	9	hSpCas9	negative selection	8789862
63544274	63544297	20	+	27260156	PATU8988T	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-1.1088206017636626	[3]	[0,0,3,0]	-9	hSpCas9	negative selection	8789863
63544227	63544250	20	+	27260156	PATU8988T	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.11414301625906409	[476]	[292,548,393,483]	-2	hSpCas9	negative selection	8789864
63540909	63540932	20	+	27260156	T47D	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.3200439149067641	[908]	[910,928,748,796]	-6	hSpCas9	negative selection	8846858
63540865	63540888	20	+	27260156	T47D	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.4165186930425897	[188]	[156,182,140,177]	-7	hSpCas9	negative selection	8846859
63541486	63541509	20	+	27260156	T47D	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.1906865038595682	[999]	[1023,938,1052,1074]	-4	hSpCas9	negative selection	8846860
63541492	63541515	20	-	27260156	T47D	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.22569809803756957	[112]	[145,110,157,205]	5	hSpCas9	negative selection	8911113
63544274	63544297	20	+	27260156	T47D	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-1.2400848581389834	[3]	[3,0,0,1]	-9	hSpCas9	negative selection	8911114
63544227	63544250	20	+	27260156	T47D	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.22538335325367959	[476]	[553,436,385,530]	-5	hSpCas9	negative selection	8911115
63540909	63540932	20	+	27260156	SU8686	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.042224954229686085	[908]	[930,735,938,906]	0	hSpCas9	negative selection	8968109
63540865	63540888	20	+	27260156	SU8686	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.2856592674073877	[188]	[238,189,268,216]	5	hSpCas9	negative selection	8968110
63541486	63541509	20	+	27260156	SU8686	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.10280745152706583	[999]	[1322,749,838,1397]	1	hSpCas9	negative selection	8968111
63541492	63541515	20	-	27260156	SU8686	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.1755674703185055	[112]	[128,104,105,174]	3	hSpCas9	negative selection	9032364
63544274	63544297	20	+	27260156	SU8686	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-0.04995412231103824	[3]	[0,1,2,10]	-1	hSpCas9	negative selection	9032365
63544227	63544250	20	+	27260156	SU8686	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.015029091468484197	[476]	[398,343,480,707]	0	hSpCas9	negative selection	9032366
63540909	63540932	20	+	27260156	SKES1	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.34401655690724475	[908]	[749,765,681,668]	-6	hSpCas9	negative selection	9089360
63540865	63540888	20	+	27260156	SKES1	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.24463700564233104	[188]	[96,287,92,163]	-5	hSpCas9	negative selection	9089361
63541486	63541509	20	+	27260156	SKES1	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.08102604550736614	[999]	[1361,945,1031,915]	1	hSpCas9	negative selection	9089362
63541492	63541515	20	-	27260156	SKES1	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.06263879928480254	[112]	[143,139,89,103]	1	hSpCas9	negative selection	9153615
63544274	63544297	20	+	27260156	SKES1	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-1.0140973523821195	[3]	[0,3,0,1]	-9	hSpCas9	negative selection	9153616
63544227	63544250	20	+	27260156	SKES1	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.13577383544852212	[476]	[466,551,631,438]	3	hSpCas9	negative selection	9153617
63540909	63540932	20	+	27260156	TOV112D	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.12643524594481492	[908]	[867,1224,804,543]	-2	hSpCas9	negative selection	9210611
63540865	63540888	20	+	27260156	TOV112D	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.43703642010139254	[188]	[249,348,229,218]	7	hSpCas9	negative selection	9210612
63541486	63541509	20	+	27260156	TOV112D	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.03242539882839024	[999]	[980,1317,833,1030]	0	hSpCas9	negative selection	9210613
63541492	63541515	20	-	27260156	TOV112D	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.056884916958860776	[112]	[222,66,55,120]	1	hSpCas9	negative selection	9274866
63544274	63544297	20	+	27260156	TOV112D	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-2.001586890435524	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	9274867
63544227	63544250	20	+	27260156	TOV112D	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.05477201916042544	[476]	[563,709,272,364]	-1	hSpCas9	negative selection	9274868
63540909	63540932	20	+	27260156	TC71	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.39423851929952847	[908]	[739,667,805,749]	-8	hSpCas9	negative selection	9331862
63540865	63540888	20	+	27260156	TC71	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	0.1270504523900886	[188]	[217,277,156,234]	3	hSpCas9	negative selection	9331863
63541486	63541509	20	+	27260156	TC71	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	-0.06333353167736	[999]	[1057,967,1059,1014]	-2	hSpCas9	negative selection	9331864
63541492	63541515	20	-	27260156	TC71	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.27165259306924106	[112]	[123,132,93,241]	6	hSpCas9	negative selection	9396117
63544274	63544297	20	+	27260156	TC71	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-1.5144640624611743	[3]	[0,2,0,0]	-9	hSpCas9	negative selection	9396118
63544227	63544250	20	+	27260156	TC71	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	-0.08757245344737109	[476]	[530,533,419,437]	-2	hSpCas9	negative selection	9396119
63540909	63540932	20	+	27260156	TC32	viability	ATGAGCACGTAGACCTCCGCCGG	SRMS	ENSG00000125508	-0.23216292073819245	[908]	[655,690,896,666]	-4	hSpCas9	negative selection	9453113
63540865	63540888	20	+	27260156	TC32	viability	CGAAGGAGGGCCGTTCCTCGGGG	SRMS	ENSG00000125508	-0.18334888058390852	[188]	[174,80,144,244]	-3	hSpCas9	negative selection	9453114
63541486	63541509	20	+	27260156	TC32	viability	CGTCGTCCACGAGCACGTTCCGG	SRMS	ENSG00000125508	0.12072356073702517	[999]	[732,712,1658,1199]	2	hSpCas9	negative selection	9453115
63541492	63541515	20	-	27260156	TC32	viability	GGCCGCCCGGAACGTGCTCGTGG	SRMS	ENSG00000125508	0.21244071466817127	[112]	[130,61,198,128]	4	hSpCas9	negative selection	9517368
63544274	63544297	20	+	27260156	TC32	viability	AAGGCCCCTGGTTCGTTGGGTGG	SRMS	ENSG00000125508	-1.8876745919276914	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	9517369
63544227	63544250	20	+	27260156	TC32	viability	CTGACAGTGAGTAGCCCCCGAGG	SRMS	ENSG00000125508	0.01521208140549947	[476]	[487,301,611,463]	0	hSpCas9	negative selection	9517370
63541485	63541508	20	-	27869803	HPAFII	viability after 27 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	0.3286329583463723	[555]	[443,302,NaN]	2	hSpCas9	negative selection	9578660
63542225	63542248	20	-	27869803	HPAFII	viability after 27 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	1.5439393233428462	[145]	[165,271,NaN]	9	hSpCas9	negative selection	9578661
63542518	63542541	20	-	27869803	HPAFII	viability after 27 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	1.2777919343912805	[89]	[51,166,NaN]	9	hSpCas9	negative selection	9578662
63544332	63544355	20	-	27869803	HPAFII	viability after 27 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.11225922250804254	[907]	[425,590,NaN]	0	hSpCas9	negative selection	9578663
63547397	63547420	20	-	27869803	HPAFII	viability after 27 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	0.2807786998366845	[350]	[125,305,NaN]	2	hSpCas9	negative selection	9578664
63541485	63541508	20	-	27869803	HPAFII	viability after 15 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	0.3228336743948328	[555]	[813,705,NaN]	4	hSpCas9	negative selection	9661109
63542225	63542248	20	-	27869803	HPAFII	viability after 15 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	0.1300780188555074	[145]	[159,178,NaN]	1	hSpCas9	negative selection	9661110
63542518	63542541	20	-	27869803	HPAFII	viability after 15 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	0.19431096926267788	[89]	[159,79,NaN]	2	hSpCas9	negative selection	9661111
63544332	63544355	20	-	27869803	HPAFII	viability after 15 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.14907979592038068	[907]	[959,1157,NaN]	1	hSpCas9	negative selection	9661112
63547397	63547420	20	-	27869803	HPAFII	viability after 15 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.6035232572657317	[350]	[304,212,NaN]	-6	hSpCas9	negative selection	9661113
63541485	63541508	20	-	27869803	ASPC1	viability after 36 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	0.6756681813391558	[1479]	[673,1242,590]	6	hSpCas9	negative selection	9743558
63542225	63542248	20	-	27869803	ASPC1	viability after 36 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	0.2997749224773372	[471]	[381,295,0]	3	hSpCas9	negative selection	9743559
63542518	63542541	20	-	27869803	ASPC1	viability after 36 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	1.2991819506370699	[237]	[485,18,151]	9	hSpCas9	negative selection	9743560
63544332	63544355	20	-	27869803	ASPC1	viability after 36 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.10590442405136669	[2705]	[1408,729,957]	1	hSpCas9	negative selection	9743561
63547397	63547420	20	-	27869803	ASPC1	viability after 36 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.6251519887129471	[716]	[108,233,140]	-6	hSpCas9	negative selection	9743562
63541485	63541508	20	-	27869803	PATU8988S	viability after 35 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-0.15312848534470547	[1583]	[666,479,NaN]	-2	hSpCas9	negative selection	9826007
63542225	63542248	20	-	27869803	PATU8988S	viability after 35 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	-0.039645033416442155	[403]	[70,245,NaN]	0	hSpCas9	negative selection	9826008
63542518	63542541	20	-	27869803	PATU8988S	viability after 35 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	0.6876255936179839	[222]	[212,75,NaN]	7	hSpCas9	negative selection	9826009
63544332	63544355	20	-	27869803	PATU8988S	viability after 35 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.3913323720438382	[2176]	[1148,1150,NaN]	4	hSpCas9	negative selection	9826010
63547397	63547420	20	-	27869803	PATU8988S	viability after 35 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.280322865789706	[817]	[389,151,NaN]	-3	hSpCas9	negative selection	9826011
63541485	63541508	20	-	27869803	PATU8988S	viability after 31 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-0.3332304508745749	[1583]	[426,595,NaN]	-4	hSpCas9	negative selection	9908456
63542225	63542248	20	-	27869803	PATU8988S	viability after 31 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	-0.06951092350958987	[403]	[127,185,NaN]	-1	hSpCas9	negative selection	9908457
63542518	63542541	20	-	27869803	PATU8988S	viability after 31 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	0.18956501370273093	[222]	[129,64,NaN]	2	hSpCas9	negative selection	9908458
63544332	63544355	20	-	27869803	PATU8988S	viability after 31 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	0.2729065474532808	[2176]	[805,1357,NaN]	3	hSpCas9	negative selection	9908459
63547397	63547420	20	-	27869803	PATU8988S	viability after 31 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.3650229419837191	[817]	[342,138,NaN]	-4	hSpCas9	negative selection	9908460
63541485	63541508	20	-	27869803	HPAFII	viability after 35 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	-0.20506390201897295	[555]	[246,240,NaN]	-1	hSpCas9	negative selection	9990905
63542225	63542248	20	-	27869803	HPAFII	viability after 35 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	1.7139285590104574	[145]	[122,376,NaN]	9	hSpCas9	negative selection	9990906
63542518	63542541	20	-	27869803	HPAFII	viability after 35 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	0.78147441876262	[89]	[3,161,NaN]	5	hSpCas9	negative selection	9990907
63544332	63544355	20	-	27869803	HPAFII	viability after 35 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	-0.00448441853526238	[907]	[358,569,NaN]	0	hSpCas9	negative selection	9990908
63547397	63547420	20	-	27869803	HPAFII	viability after 35 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.2392590863181615	[350]	[47,265,NaN]	-1	hSpCas9	negative selection	9990909
63541485	63541508	20	-	27869803	HPAFII	viability after 31 days	CGGAACGTGCTCGTGGACGACGG	SRMS	ENSG00000125508	0.05208388319715751	[555]	[345,298,NaN]	0	hSpCas9	negative selection	10073354
63542225	63542248	20	-	27869803	HPAFII	viability after 31 days	CTGCACGCAGTGTGCTCGGGCGG	SRMS	ENSG00000125508	1.5217727601355104	[145]	[140,337,NaN]	9	hSpCas9	negative selection	10073355
63542518	63542541	20	-	27869803	HPAFII	viability after 31 days	ATTCGCCCTTGGGAGGAAGCTGG	SRMS	ENSG00000125508	1.6786302416153225	[89]	[31,302,NaN]	9	hSpCas9	negative selection	10073356
63544332	63544355	20	-	27869803	HPAFII	viability after 31 days	TTGCAGCTGGTACTTTAGCGGGG	SRMS	ENSG00000125508	-7.715538710750813e-05	[907]	[454,568,NaN]	0	hSpCas9	negative selection	10073357
63547397	63547420	20	-	27869803	HPAFII	viability after 31 days	CTGGGACAAGATCTGGCCGGCGG	SRMS	ENSG00000125508	-0.012249595926616563	[350]	[101,296,NaN]	0	hSpCas9	negative selection	10073358
63547240	63547263	20	-	28162770	P31FUJ	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	-0.47381030391817347	[194]	[164]	-4	hSpCas9	negative selection	10242997
63544300	63544323	20	+	28162770	P31FUJ	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.5491633743911786	[302]	[520]	6	hSpCas9	negative selection	10242998
63542497	63542520	20	-	28162770	P31FUJ	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	-0.6357668713926473	[118]	[89]	-5	hSpCas9	negative selection	10242999
63547308	63547331	20	+	28162770	P31FUJ	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	0.7867379819812664	[109]	[222]	8	hSpCas9	negative selection	10243000
63547286	63547309	20	+	28162770	P31FUJ	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	-0.05096388142856556	[133]	[151]	0	hSpCas9	negative selection	10243001
63542292	63542315	20	-	28162770	P31FUJ	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	0.33334598645309055	[282]	[418]	3	hSpCas9	negative selection	10243002
63541540	63541563	20	-	28162770	P31FUJ	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	-0.03714963103035185	[598]	[685]	0	hSpCas9	negative selection	10243003
63547393	63547416	20	-	28162770	P31FUJ	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	0.5462888654245039	[80]	[138]	6	hSpCas9	negative selection	10243004
63547165	63547188	20	-	28162770	P31FUJ	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	0.7851197035828836	[199]	[404]	8	hSpCas9	negative selection	10243005
63547240	63547263	20	-	28162770	TF1	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10412363
63544300	63544323	20	+	28162770	TF1	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	NaN	[NaN]	[340]	1	hSpCas9	negative selection	10412364
63542497	63542520	20	-	28162770	TF1	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10412365
63547308	63547331	20	+	28162770	TF1	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10412366
63547286	63547309	20	+	28162770	TF1	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10412367
63542292	63542315	20	-	28162770	TF1	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	NaN	[NaN]	[249]	1	hSpCas9	negative selection	10412368
63541540	63541563	20	-	28162770	TF1	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10412369
63547393	63547416	20	-	28162770	TF1	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	NaN	[NaN]	[226]	1	hSpCas9	negative selection	10412370
63547165	63547188	20	-	28162770	TF1	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10412371
63547240	63547263	20	-	28162770	SKM1	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	-0.646151862622588	[53]	[60]	-5	hSpCas9	negative selection	10581729
63544300	63544323	20	+	28162770	SKM1	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.3277454214826765	[63]	[141]	3	hSpCas9	negative selection	10581730
63542497	63542520	20	-	28162770	SKM1	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	-0.2370391973008492	[19]	[29]	-2	hSpCas9	negative selection	10581731
63547308	63547331	20	+	28162770	SKM1	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	-0.13012399338433733	[38]	[62]	-1	hSpCas9	negative selection	10581732
63547286	63547309	20	+	28162770	SKM1	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	0.4454786128429804	[26]	[64]	4	hSpCas9	negative selection	10581733
63542292	63542315	20	-	28162770	SKM1	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	-0.017257989420939368	[78]	[137]	0	hSpCas9	negative selection	10581734
63541540	63541563	20	-	28162770	SKM1	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	-0.22554355846302	[124]	[188]	-2	hSpCas9	negative selection	10581735
63547393	63547416	20	-	28162770	SKM1	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	0.00112053989391514	[12]	[22]	0	hSpCas9	negative selection	10581736
63547165	63547188	20	-	28162770	SKM1	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	0.1950718153369359	[41]	[84]	2	hSpCas9	negative selection	10581737
63547240	63547263	20	-	28162770	SKM1	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	-0.646151862622588	[53]	[60]	-5	hSpCas9	negative selection	10751095
63544300	63544323	20	+	28162770	SKM1	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.3277454214826765	[63]	[141]	3	hSpCas9	negative selection	10751096
63542497	63542520	20	-	28162770	SKM1	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	-0.2370391973008492	[19]	[29]	-2	hSpCas9	negative selection	10751097
63547308	63547331	20	+	28162770	SKM1	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	-0.13012399338433733	[38]	[62]	-1	hSpCas9	negative selection	10751098
63547286	63547309	20	+	28162770	SKM1	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	0.4454786128429804	[26]	[64]	4	hSpCas9	negative selection	10751099
63542292	63542315	20	-	28162770	SKM1	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	-0.017257989420939368	[78]	[137]	0	hSpCas9	negative selection	10751100
63541540	63541563	20	-	28162770	SKM1	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	-0.22554355846302	[124]	[188]	-2	hSpCas9	negative selection	10751101
63547393	63547416	20	-	28162770	SKM1	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	0.00112053989391514	[12]	[22]	0	hSpCas9	negative selection	10751102
63547165	63547188	20	-	28162770	SKM1	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	0.1950718153369359	[41]	[84]	2	hSpCas9	negative selection	10751103
63547240	63547263	20	-	28162770	PL21	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	-0.5103537683156949	[143]	[43]	-4	hSpCas9	negative selection	10920461
63544300	63544323	20	+	28162770	PL21	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.18454275943830145	[278]	[137]	1	hSpCas9	negative selection	10920462
63542497	63542520	20	-	28162770	PL21	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	0.2672538103478572	[83]	[43]	2	hSpCas9	negative selection	10920463
63547308	63547331	20	+	28162770	PL21	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	-0.9403416090605102	[96]	[21]	-6	hSpCas9	negative selection	10920464
63547286	63547309	20	+	28162770	PL21	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	-0.12178848039804224	[79]	[31]	-1	hSpCas9	negative selection	10920465
63542292	63542315	20	-	28162770	PL21	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	-0.6115026659713823	[336]	[95]	-4	hSpCas9	negative selection	10920466
63541540	63541563	20	-	28162770	PL21	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	-0.0648325955859661	[446]	[185]	0	hSpCas9	negative selection	10920467
63547393	63547416	20	-	28162770	PL21	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	-0.09942066736958766	[63]	[25]	0	hSpCas9	negative selection	10920468
63547165	63547188	20	-	28162770	PL21	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	0.6994460306657679	[132]	[93]	6	hSpCas9	negative selection	10920469
63547240	63547263	20	-	28162770	P31FUJ	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	-0.47381030391817347	[194]	[164]	-4	hSpCas9	negative selection	11089827
63544300	63544323	20	+	28162770	P31FUJ	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.5491633743911786	[302]	[520]	6	hSpCas9	negative selection	11089828
63542497	63542520	20	-	28162770	P31FUJ	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	-0.6357668713926473	[118]	[89]	-5	hSpCas9	negative selection	11089829
63547308	63547331	20	+	28162770	P31FUJ	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	0.7867379819812664	[109]	[222]	8	hSpCas9	negative selection	11089830
63547286	63547309	20	+	28162770	P31FUJ	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	-0.05096388142856556	[133]	[151]	0	hSpCas9	negative selection	11089831
63542292	63542315	20	-	28162770	P31FUJ	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	0.33334598645309055	[282]	[418]	3	hSpCas9	negative selection	11089832
63541540	63541563	20	-	28162770	P31FUJ	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	-0.03714963103035185	[598]	[685]	0	hSpCas9	negative selection	11089833
63547393	63547416	20	-	28162770	P31FUJ	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	0.5462888654245039	[80]	[138]	6	hSpCas9	negative selection	11089834
63547165	63547188	20	-	28162770	P31FUJ	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	0.7851197035828836	[199]	[404]	8	hSpCas9	negative selection	11089835
63547240	63547263	20	-	28162770	OCIAML5	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	-1.35902655958388	[53]	[37]	-7	hSpCas9	negative selection	11259193
63544300	63544323	20	+	28162770	OCIAML5	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.6200018734512256	[154]	[429]	5	hSpCas9	negative selection	11259194
63542497	63542520	20	-	28162770	OCIAML5	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	-1.2043683147948783	[59]	[46]	-6	hSpCas9	negative selection	11259195
63547308	63547331	20	+	28162770	OCIAML5	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	0.1328265367457946	[47]	[94]	1	hSpCas9	negative selection	11259196
63547286	63547309	20	+	28162770	OCIAML5	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	0.38059418592627803	[39]	[93]	3	hSpCas9	negative selection	11259197
63542292	63542315	20	-	28162770	OCIAML5	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	0.6865259667191252	[136]	[397]	6	hSpCas9	negative selection	11259198
63541540	63541563	20	-	28162770	OCIAML5	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	-0.43702907158515325	[395]	[527]	-3	hSpCas9	negative selection	11259199
63547393	63547416	20	-	28162770	OCIAML5	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	-0.8520665708639971	[62]	[62]	-5	hSpCas9	negative selection	11259200
63547165	63547188	20	-	28162770	OCIAML5	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	0.23282232672251627	[131]	[279]	2	hSpCas9	negative selection	11259201
63547240	63547263	20	-	28162770	EOL1	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	-0.3908571997354934	[330]	[132]	-3	hSpCas9	negative selection	11428559
63544300	63544323	20	+	28162770	EOL1	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.7496046953615977	[323]	[286]	6	hSpCas9	negative selection	11428560
63542497	63542520	20	-	28162770	EOL1	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	0.6094517101655976	[157]	[126]	5	hSpCas9	negative selection	11428561
63547308	63547331	20	+	28162770	EOL1	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	1.1719853223533099	[154]	[183]	8	hSpCas9	negative selection	11428562
63547286	63547309	20	+	28162770	EOL1	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	0.5887570233014267	[182]	[144]	5	hSpCas9	negative selection	11428563
63542292	63542315	20	-	28162770	EOL1	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	-0.9637271458706371	[384]	[103]	-6	hSpCas9	negative selection	11428564
63541540	63541563	20	-	28162770	EOL1	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	1.2835451211492683	[583]	[748]	9	hSpCas9	negative selection	11428565
63547393	63547416	20	-	28162770	EOL1	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	-0.2453772298717778	[107]	[47]	-2	hSpCas9	negative selection	11428566
63547165	63547188	20	-	28162770	EOL1	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	0.18989233809152956	[207]	[124]	1	hSpCas9	negative selection	11428567
63547240	63547263	20	-	28162770	MOLM13	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	0.039046082740704646	[174]	[129]	0	hSpCas9	negative selection	11597925
63544300	63544323	20	+	28162770	MOLM13	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	-0.15192695131251605	[397]	[258]	-1	hSpCas9	negative selection	11597926
63542497	63542520	20	-	28162770	MOLM13	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	-0.2545766429265123	[164]	[99]	-1	hSpCas9	negative selection	11597927
63547308	63547331	20	+	28162770	MOLM13	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	0.25949023228763085	[170]	[147]	1	hSpCas9	negative selection	11597928
63547286	63547309	20	+	28162770	MOLM13	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	0.5458918935458519	[161]	[170]	4	hSpCas9	negative selection	11597929
63542292	63542315	20	-	28162770	MOLM13	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	-0.4640463435102671	[413]	[216]	-3	hSpCas9	negative selection	11597930
63541540	63541563	20	-	28162770	MOLM13	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	-0.41793959853611007	[594]	[321]	-2	hSpCas9	negative selection	11597931
63547393	63547416	20	-	28162770	MOLM13	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	-1.2834315055986978	[100]	[29]	-6	hSpCas9	negative selection	11597932
63547165	63547188	20	-	28162770	MOLM13	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	1.0329523248280301	[218]	[323]	7	hSpCas9	negative selection	11597933
63547240	63547263	20	-	28162770	HEL	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	-0.17478311621424603	[177]	[100]	-1	hSpCas9	negative selection	11767291
63544300	63544323	20	+	28162770	HEL	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.5405153234085669	[306]	[285]	4	hSpCas9	negative selection	11767292
63542497	63542520	20	-	28162770	HEL	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	0.7172857853654111	[131]	[138]	6	hSpCas9	negative selection	11767293
63547308	63547331	20	+	28162770	HEL	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	0.6330886619666376	[149]	[148]	5	hSpCas9	negative selection	11767294
63547286	63547309	20	+	28162770	HEL	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	0.17418582339451127	[118]	[85]	1	hSpCas9	negative selection	11767295
63542292	63542315	20	-	28162770	HEL	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	-0.8965315780279304	[403]	[138]	-5	hSpCas9	negative selection	11767296
63541540	63541563	20	-	28162770	HEL	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	-0.24634526659779243	[462]	[249]	-2	hSpCas9	negative selection	11767297
63547393	63547416	20	-	28162770	HEL	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	0.2339332864330277	[76]	[57]	2	hSpCas9	negative selection	11767298
63547165	63547188	20	-	28162770	HEL	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	1.3052379331925335	[162]	[257]	9	hSpCas9	negative selection	11767299
63547240	63547263	20	-	28162770	MV411	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	-0.3566337728860856	[151]	[99]	-3	hSpCas9	negative selection	11936657
63544300	63544323	20	+	28162770	MV411	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.8324000515039314	[205]	[308]	7	hSpCas9	negative selection	11936658
63542497	63542520	20	-	28162770	MV411	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	-1.2710295381514742	[105]	[36]	-7	hSpCas9	negative selection	11936659
63547308	63547331	20	+	28162770	MV411	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	0.5857600839208061	[139]	[176]	5	hSpCas9	negative selection	11936660
63547286	63547309	20	+	28162770	MV411	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	-0.8418297873143119	[99]	[46]	-5	hSpCas9	negative selection	11936661
63542292	63542315	20	-	28162770	MV411	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	-0.16342427252487518	[229]	[172]	-1	hSpCas9	negative selection	11936662
63541540	63541563	20	-	28162770	MV411	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	0.02626516760858344	[393]	[337]	0	hSpCas9	negative selection	11936663
63547393	63547416	20	-	28162770	MV411	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	-0.5638008057620569	[92]	[52]	-4	hSpCas9	negative selection	11936664
63547165	63547188	20	-	28162770	MV411	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	1.6980989597923406	[134]	[368]	9	hSpCas9	negative selection	11936665
63547240	63547263	20	-	28162770	MONOMAC1	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	0.294816249270121	[95]	[134]	3	hSpCas9	negative selection	12106023
63544300	63544323	20	+	28162770	MONOMAC1	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.21522356754871658	[129]	[172]	2	hSpCas9	negative selection	12106024
63542497	63542520	20	-	28162770	MONOMAC1	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	1.0135301388801048	[34]	[80]	8	hSpCas9	negative selection	12106025
63547308	63547331	20	+	28162770	MONOMAC1	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	0.01708795829329368	[74]	[86]	0	hSpCas9	negative selection	12106026
63547286	63547309	20	+	28162770	MONOMAC1	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	-0.3728866824589714	[60]	[53]	-3	hSpCas9	negative selection	12106027
63542292	63542315	20	-	28162770	MONOMAC1	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	0.18088119665859048	[186]	[242]	1	hSpCas9	negative selection	12106028
63541540	63541563	20	-	28162770	MONOMAC1	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	0.12272014878618132	[265]	[331]	1	hSpCas9	negative selection	12106029
63547393	63547416	20	-	28162770	MONOMAC1	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	-0.44701510006790124	[43]	[36]	-4	hSpCas9	negative selection	12106030
63547165	63547188	20	-	28162770	MONOMAC1	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	0.1558441761567207	[82]	[105]	1	hSpCas9	negative selection	12106031
63547240	63547263	20	-	28162770	OCIAML2	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	0.29121043756307435	[22]	[155]	3	hSpCas9	negative selection	12275389
63544300	63544323	20	+	28162770	OCIAML2	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.5960412144031266	[36]	[309]	6	hSpCas9	negative selection	12275390
63542497	63542520	20	-	28162770	OCIAML2	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	0.09124906236595365	[20]	[123]	0	hSpCas9	negative selection	12275391
63547308	63547331	20	+	28162770	OCIAML2	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	0.5379321882612629	[20]	[168]	5	hSpCas9	negative selection	12275392
63547286	63547309	20	+	28162770	OCIAML2	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	-0.4562745322650911	[24]	[100]	-4	hSpCas9	negative selection	12275393
63542292	63542315	20	-	28162770	OCIAML2	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	0.06224416433054081	[46]	[271]	0	hSpCas9	negative selection	12275394
63541540	63541563	20	-	28162770	OCIAML2	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	0.24557720875724753	[62]	[413]	2	hSpCas9	negative selection	12275395
63547393	63547416	20	-	28162770	OCIAML2	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	0.3159665366486455	[9]	[68]	3	hSpCas9	negative selection	12275396
63547165	63547188	20	-	28162770	OCIAML2	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	0.03187051528702206	[32]	[186]	0	hSpCas9	negative selection	12275397
63547240	63547263	20	-	28162770	OCIAML3	viability	GGGGAGCTGAGTGTCCGCCGCGG	SRMS	ENSG00000125508	0.16783262248107222	[45]	[155]	1	hSpCas9	negative selection	12444755
63544300	63544323	20	+	28162770	OCIAML3	viability	GAGGAGCAGCTGCTGTGCCTGGG	SRMS	ENSG00000125508	0.7999065673889266	[42]	[225]	7	hSpCas9	negative selection	12444756
63542497	63542520	20	-	28162770	OCIAML3	viability	GGGTGAAGGCTACTTTGGGGAGG	SRMS	ENSG00000125508	-0.7315111640740981	[32]	[59]	-5	hSpCas9	negative selection	12444757
63547308	63547331	20	+	28162770	OCIAML3	viability	GAAGGGGCTGCAAGGCTCGGCGG	SRMS	ENSG00000125508	0.5214695770957727	[26]	[116]	5	hSpCas9	negative selection	12444758
63547286	63547309	20	+	28162770	OCIAML3	viability	AGAGCGCAAGGAAGAGCTGAGGG	SRMS	ENSG00000125508	0.8053992072409166	[28]	[152]	7	hSpCas9	negative selection	12444759
63542292	63542315	20	-	28162770	OCIAML3	viability	GAAGCTCACTGACCTCGCCAAGG	SRMS	ENSG00000125508	-0.5940076403241633	[85]	[171]	-4	hSpCas9	negative selection	12444760
63541540	63541563	20	-	28162770	OCIAML3	viability	TGAGGGCATGAGCTACCTGGAGG	SRMS	ENSG00000125508	0.42653973707992265	[121]	[494]	4	hSpCas9	negative selection	12444761
63547393	63547416	20	-	28162770	OCIAML3	viability	GACAAGATCTGGCCGGCGGGCGG	SRMS	ENSG00000125508	0.6283847810122849	[11]	[55]	6	hSpCas9	negative selection	12444762
63547165	63547188	20	-	28162770	OCIAML3	viability	CTTTCGGGCCAGCCCAGCGCCGG	SRMS	ENSG00000125508	1.2719750117041495	[30]	[225]	9	hSpCas9	negative selection	12444763