Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 53373
• Symbol: TPCN1
• Description: two pore segment channel 1

DataSource: http://genomecrispr.dkfz.de/#!/results/TPCN1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
113266197	113266220	12	+	26472758	Jiyoye	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	-0.011428732793162755	[134]	[100]	0	hSpCas9	negative selection	170890
113266283	113266306	12	-	26472758	Jiyoye	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	-0.48034988923571387	[36]	[19]	-3	hSpCas9	negative selection	170891
113266209	113266232	12	-	26472758	Jiyoye	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	0.21125517153061646	[62]	[54]	1	hSpCas9	negative selection	170892
113267857	113267880	12	+	26472758	Jiyoye	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	-0.4231528769560702	[632]	[355]	-3	hSpCas9	negative selection	170893
113268841	113268864	12	+	26472758	Jiyoye	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	-0.869664823852951	[188]	[77]	-6	hSpCas9	negative selection	170894
113285878	113285901	12	+	26472758	Jiyoye	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	-0.23477709780011247	[283]	[181]	-2	hSpCas9	negative selection	170895
113288796	113288819	12	-	26472758	Jiyoye	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	-0.8284528669872686	[72]	[30]	-5	hSpCas9	negative selection	170896
113290152	113290175	12	+	26472758	Jiyoye	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	-1.391190757324476	[159]	[45]	-7	hSpCas9	negative selection	170897
113290173	113290196	12	+	26472758	Jiyoye	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	-1.7542880411882429	[169]	[37]	-8	hSpCas9	negative selection	170898
113226893	113226916	12	-	26472758	Jiyoye	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	-0.7865057431890471	[397]	[173]	-5	hSpCas9	negative selection	170899
113266197	113266220	12	+	26472758	KBM7	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	0.17745618029879484	[509,313]	[208,219]	1	hSpCas9	negative selection	362008
113266283	113266306	12	-	26472758	KBM7	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	0.2190326331765884	[60,55]	[21,40]	2	hSpCas9	negative selection	362009
113266209	113266232	12	-	26472758	KBM7	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-0.6208865985025251	[392,265]	[103,94]	-5	hSpCas9	negative selection	362010
113267857	113267880	12	+	26472758	KBM7	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	-0.08640424486282838	[1484,1178]	[626,548]	-1	hSpCas9	negative selection	362011
113268841	113268864	12	+	26472758	KBM7	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	0.5673212672112837	[340,213]	[184,193]	6	hSpCas9	negative selection	362012
113285878	113285901	12	+	26472758	KBM7	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	0.12314543889636864	[1245,1063]	[795,404]	1	hSpCas9	negative selection	362013
113288796	113288819	12	-	26472758	KBM7	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	0.14027555153512233	[434,256]	[232,123]	1	hSpCas9	negative selection	362014
113290152	113290175	12	+	26472758	KBM7	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	0.43094699565932765	[502,254]	[301,171]	4	hSpCas9	negative selection	362015
113290173	113290196	12	+	26472758	KBM7	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	-0.938824515169105	[175,218]	[63,35]	-6	hSpCas9	negative selection	362016
113226893	113226916	12	-	26472758	KBM7	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	0.35557864325219324	[1158,1171]	[610,788]	4	hSpCas9	negative selection	362017
113266197	113266220	12	+	26472758	Raji	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	-0.5856387112050097	[290]	[44]	-5	hSpCas9	negative selection	553126
113266283	113266306	12	-	26472758	Raji	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	-1.140543978069986	[37]	[3]	-7	hSpCas9	negative selection	553127
113266209	113266232	12	-	26472758	Raji	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	0.40336836300867984	[100]	[30]	4	hSpCas9	negative selection	553128
113267857	113267880	12	+	26472758	Raji	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	-0.5278979186631154	[670]	[107]	-4	hSpCas9	negative selection	553129
113268841	113268864	12	+	26472758	Raji	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	-0.7406133711813506	[143]	[19]	-5	hSpCas9	negative selection	553130
113285878	113285901	12	+	26472758	Raji	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	0.5811434737751457	[336]	[116]	5	hSpCas9	negative selection	553131
113288796	113288819	12	-	26472758	Raji	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	-0.22232191010548202	[185]	[36]	-2	hSpCas9	negative selection	553132
113290152	113290175	12	+	26472758	Raji	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	0.4390050264648056	[177]	[55]	4	hSpCas9	negative selection	553133
113290173	113290196	12	+	26472758	Raji	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	-1.0964887979920506	[128]	[13]	-7	hSpCas9	negative selection	553134
113226893	113226916	12	-	26472758	Raji	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	0.3627643686639579	[629]	[187]	3	hSpCas9	negative selection	553135
113266197	113266220	12	+	26472758	K562	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	0.1180073481241376	[297]	[272]	0	hSpCas9	negative selection	744244
113266283	113266306	12	-	26472758	K562	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	-0.3670159844159002	[54]	[35]	-2	hSpCas9	negative selection	744245
113266209	113266232	12	-	26472758	K562	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-0.9884660674876433	[321]	[136]	-5	hSpCas9	negative selection	744246
113267857	113267880	12	+	26472758	K562	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	-0.15568098137802755	[1184]	[897]	-1	hSpCas9	negative selection	744247
113268841	113268864	12	+	26472758	K562	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	-0.17247671783297946	[258]	[193]	-1	hSpCas9	negative selection	744248
113285878	113285901	12	+	26472758	K562	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	-0.2552964864361982	[1034]	[731]	-2	hSpCas9	negative selection	744249
113288796	113288819	12	-	26472758	K562	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	0.5684825668978003	[269]	[337]	4	hSpCas9	negative selection	744250
113290152	113290175	12	+	26472758	K562	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	0.5022966994757168	[326]	[390]	4	hSpCas9	negative selection	744251
113290173	113290196	12	+	26472758	K562	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	0.7823837488504337	[207]	[301]	6	hSpCas9	negative selection	744252
113226893	113226916	12	-	26472758	K562	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	-0.49492951781075334	[1009]	[604]	-3	hSpCas9	negative selection	744253
113226918	113226941	12	+	26627737	DLD1	viability	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	0.6950247020723601	[126]	[15,96,78]	7	hSpCas9	negative selection	782312
113260453	113260476	12	+	26627737	DLD1	viability	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	1.166071969096433	[285]	[126,182,278]	9	hSpCas9	negative selection	782313
113266341	113266364	12	-	26627737	DLD1	viability	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.6325507565415096	[718]	[249,422,371]	6	hSpCas9	negative selection	782314
113267845	113267868	12	-	26627737	DLD1	viability	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	0.38928666313556626	[403]	[305,60,129]	4	hSpCas9	negative selection	782315
113268851	113268874	12	+	26627737	DLD1	viability	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	0.13827362895210893	[100]	[20,43,38]	1	hSpCas9	negative selection	782316
113269781	113269804	12	-	26627737	DLD1	viability	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	-1.4230383540818967	[261]	[64,5,20]	-8	hSpCas9	negative selection	782317
113226918	113226941	12	+	26627737	GBM cells	viability after 5 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	0.9969459578462124	[63]	[38,97]	9	hSpCas9	negative selection	864627
113260453	113260476	12	+	26627737	GBM cells	viability after 5 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	-0.7094315532734213	[310]	[98,104]	-8	hSpCas9	negative selection	864628
113266341	113266364	12	-	26627737	GBM cells	viability after 5 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.5158664898512787	[445]	[313,369]	7	hSpCas9	negative selection	864629
113267845	113267868	12	-	26627737	GBM cells	viability after 5 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	0.46010820967389193	[203]	[156,143]	7	hSpCas9	negative selection	864630
113268851	113268874	12	+	26627737	GBM cells	viability after 5 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	-0.7363218323166942	[72]	[11,34]	-8	hSpCas9	negative selection	864631
113269781	113269804	12	-	26627737	GBM cells	viability after 5 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	-0.344129055760642	[128]	[55,52]	-5	hSpCas9	negative selection	864632
113226918	113226941	12	+	26627737	GBM cells	viability after 13 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	-0.3090273137619497	[63]	[16,36]	-4	hSpCas9	negative selection	946942
113260453	113260476	12	+	26627737	GBM cells	viability after 13 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	-0.23095435034277426	[310]	[188,106]	-3	hSpCas9	negative selection	946943
113266341	113266364	12	-	26627737	GBM cells	viability after 13 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.13971231957720764	[445]	[361,188]	1	hSpCas9	negative selection	946944
113267845	113267868	12	-	26627737	GBM cells	viability after 13 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-0.18669587340685634	[203]	[115,81]	-2	hSpCas9	negative selection	946945
113268851	113268874	12	+	26627737	GBM cells	viability after 13 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	-0.7139458647741044	[72]	[43,7]	-7	hSpCas9	negative selection	946946
113269781	113269804	12	-	26627737	GBM cells	viability after 13 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	-0.30913293477652126	[128]	[77,38]	-4	hSpCas9	negative selection	946947
113226918	113226941	12	+	26627737	GBM cells	viability after 21 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	-0.37440983595899446	[63]	[30,22]	-3	hSpCas9	negative selection	1029257
113260453	113260476	12	+	26627737	GBM cells	viability after 21 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.02190112348684048	[310]	[193,150]	0	hSpCas9	negative selection	1029258
113266341	113266364	12	-	26627737	GBM cells	viability after 21 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.0947794274884447	[445]	[287,231]	1	hSpCas9	negative selection	1029259
113267845	113267868	12	-	26627737	GBM cells	viability after 21 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	0.44748603777642987	[203]	[147,153]	4	hSpCas9	negative selection	1029260
113268851	113268874	12	+	26627737	GBM cells	viability after 21 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	-1.2788628243392035	[72]	[19,12]	-8	hSpCas9	negative selection	1029261
113269781	113269804	12	-	26627737	GBM cells	viability after 21 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	0.2569276251996562	[128]	[77,88]	2	hSpCas9	negative selection	1029262
113226918	113226941	12	+	26627737	RPE1	viability after 9 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	-0.09804189299885668	[227]	[67,64]	0	hSpCas9	negative selection	1111572
113260453	113260476	12	+	26627737	RPE1	viability after 9 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	2.167314059605201	[218]	[169,485]	9	hSpCas9	negative selection	1111573
113266341	113266364	12	-	26627737	RPE1	viability after 9 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	1.7597759550171146	[492]	[392,689]	8	hSpCas9	negative selection	1111574
113267845	113267868	12	-	26627737	RPE1	viability after 9 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-1.096277215150863	[1704]	[298,185]	-7	hSpCas9	negative selection	1111575
113268851	113268874	12	+	26627737	RPE1	viability after 9 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	4.593133771566659	[1]	[8,22]	9	hSpCas9	negative selection	1111576
113269781	113269804	12	-	26627737	RPE1	viability after 9 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	4.721763576731192	[31]	[190,358]	9	hSpCas9	negative selection	1111577
113226918	113226941	12	+	26627737	RPE1	viability after 12 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	0.3062593354306886	[227]	[66,84]	2	hSpCas9	negative selection	1193887
113260453	113260476	12	+	26627737	RPE1	viability after 12 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	2.259413266392272	[218]	[118,453]	9	hSpCas9	negative selection	1193888
113266341	113266364	12	-	26627737	RPE1	viability after 12 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	2.1098902020445496	[492]	[460,688]	9	hSpCas9	negative selection	1193889
113267845	113267868	12	-	26627737	RPE1	viability after 12 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-0.7944260847157324	[1704]	[301,223]	-5	hSpCas9	negative selection	1193890
113268851	113268874	12	+	26627737	RPE1	viability after 12 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	3.946737484743106	[1]	[0,15]	9	hSpCas9	negative selection	1193891
113269781	113269804	12	-	26627737	RPE1	viability after 12 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	4.7342347990399425	[31]	[171,288]	9	hSpCas9	negative selection	1193892
113226918	113226941	12	+	26627737	RPE1	viability after 15 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	-0.3667628024701177	[227]	[48,50]	-2	hSpCas9	negative selection	1276202
113260453	113260476	12	+	26627737	RPE1	viability after 15 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	2.1511751193728097	[218]	[208,338]	9	hSpCas9	negative selection	1276203
113266341	113266364	12	-	26627737	RPE1	viability after 15 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	1.6992615150787178	[492]	[431,472]	8	hSpCas9	negative selection	1276204
113267845	113267868	12	-	26627737	RPE1	viability after 15 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-0.7924494431922997	[1704]	[195,357]	-5	hSpCas9	negative selection	1276205
113268851	113268874	12	+	26627737	RPE1	viability after 15 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	0.8217488738718943	[1]	[0,0]	5	hSpCas9	negative selection	1276206
113269781	113269804	12	-	26627737	RPE1	viability after 15 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	5.1392126468539665	[31]	[233,400]	9	hSpCas9	negative selection	1276207
113226918	113226941	12	+	26627737	RPE1	viability after 18 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	0.6042941553447216	[227]	[152,29]	4	hSpCas9	negative selection	1358517
113260453	113260476	12	+	26627737	RPE1	viability after 18 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	2.7595918143684948	[218]	[71,750]	9	hSpCas9	negative selection	1358518
113266341	113266364	12	-	26627737	RPE1	viability after 18 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	1.6562868287629726	[492]	[327,516]	8	hSpCas9	negative selection	1358519
113267845	113267868	12	-	26627737	RPE1	viability after 18 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-0.8952524042741343	[1704]	[214,281]	-5	hSpCas9	negative selection	1358520
113268851	113268874	12	+	26627737	RPE1	viability after 18 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	1.4585879183261756	[1]	[0,1]	7	hSpCas9	negative selection	1358521
113269781	113269804	12	-	26627737	RPE1	viability after 18 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	5.220436491052188	[31]	[116,540]	9	hSpCas9	negative selection	1358522
113226918	113226941	12	+	26627737	HeLa	viability after 8 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	0.08045754322658705	[115]	[42,63,50]	0	hSpCas9	negative selection	1440832
113260453	113260476	12	+	26627737	HeLa	viability after 8 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	1.215990891606432	[212]	[204,361,85]	8	hSpCas9	negative selection	1440833
113266341	113266364	12	-	26627737	HeLa	viability after 8 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.02775555402953933	[879]	[451,243,481]	0	hSpCas9	negative selection	1440834
113267845	113267868	12	-	26627737	HeLa	viability after 8 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-0.7764046607643674	[610]	[208,105,161]	-7	hSpCas9	negative selection	1440835
113268851	113268874	12	+	26627737	HeLa	viability after 8 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	0.4667392337812055	[70]	[9,54,54]	4	hSpCas9	negative selection	1440836
113269781	113269804	12	-	26627737	HeLa	viability after 8 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	-0.27972138970961835	[297]	[93,151,73]	-3	hSpCas9	negative selection	1440837
113226918	113226941	12	+	26627737	HeLa	viability after 12 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	1.728852139776107	[115]	[380,65,45]	9	hSpCas9	negative selection	1523147
113260453	113260476	12	+	26627737	HeLa	viability after 12 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.8838244139670479	[212]	[282,84,130]	6	hSpCas9	negative selection	1523148
113266341	113266364	12	-	26627737	HeLa	viability after 12 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.27330819689878605	[879]	[620,390,316]	2	hSpCas9	negative selection	1523149
113267845	113267868	12	-	26627737	HeLa	viability after 12 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-0.25554899913058704	[610]	[175,121,344]	-2	hSpCas9	negative selection	1523150
113268851	113268874	12	+	26627737	HeLa	viability after 12 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	-0.26236599347822365	[70]	[10,14,47]	-2	hSpCas9	negative selection	1523151
113269781	113269804	12	-	26627737	HeLa	viability after 12 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	-0.13311908773784142	[297]	[107,128,97]	-1	hSpCas9	negative selection	1523152
113226918	113226941	12	+	26627737	HeLa	viability after 15 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	1.3218562979936825	[115]	[210,107,26]	8	hSpCas9	negative selection	1605462
113260453	113260476	12	+	26627737	HeLa	viability after 15 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	1.2418537561082315	[212]	[292,237,72]	8	hSpCas9	negative selection	1605463
113266341	113266364	12	-	26627737	HeLa	viability after 15 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.3966528083360621	[879]	[497,583,320]	3	hSpCas9	negative selection	1605464
113267845	113267868	12	-	26627737	HeLa	viability after 15 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-0.3999162415279158	[610]	[166,304,85]	-3	hSpCas9	negative selection	1605465
113268851	113268874	12	+	26627737	HeLa	viability after 15 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	-0.6004908054403413	[70]	[21,29,3]	-5	hSpCas9	negative selection	1605466
113269781	113269804	12	-	26627737	HeLa	viability after 15 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	-0.07476394331367137	[297]	[139,80,124]	0	hSpCas9	negative selection	1605467
113226918	113226941	12	+	26627737	HeLa	viability after 18 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	1.323641997909708	[115]	[138,92,26]	8	hSpCas9	negative selection	1687777
113260453	113260476	12	+	26627737	HeLa	viability after 18 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	1.2057844693090651	[212]	[185,197,72]	8	hSpCas9	negative selection	1687778
113266341	113266364	12	-	26627737	HeLa	viability after 18 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.3696744323821368	[879]	[323,474,320]	3	hSpCas9	negative selection	1687779
113267845	113267868	12	-	26627737	HeLa	viability after 18 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-0.38695163678126093	[610]	[114,252,85]	-3	hSpCas9	negative selection	1687780
113268851	113268874	12	+	26627737	HeLa	viability after 18 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	-0.5112516872544717	[70]	[16,24,3]	-4	hSpCas9	negative selection	1687781
113269781	113269804	12	-	26627737	HeLa	viability after 18 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	-0.0772871697033996	[297]	[91,68,124]	0	hSpCas9	negative selection	1687782
113226918	113226941	12	+	26627737	HCT116	viability after 6 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	0.6420462305201564	[139]	[92,1]	3	hSpCas9	negative selection	1770092
113260453	113260476	12	+	26627737	HCT116	viability after 6 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	2.0770616239392776	[511]	[454,275]	8	hSpCas9	negative selection	1770093
113266341	113266364	12	-	26627737	HCT116	viability after 6 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.36582348666538445	[1153]	[236,231]	2	hSpCas9	negative selection	1770094
113267845	113267868	12	-	26627737	HCT116	viability after 6 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-1.7698554228848344	[519]	[61,2]	-7	hSpCas9	negative selection	1770095
113268851	113268874	12	+	26627737	HCT116	viability after 6 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	-1.5258095641532972	[126]	[4,7]	-7	hSpCas9	negative selection	1770096
113269781	113269804	12	-	26627737	HCT116	viability after 6 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	3.6809708853704572	[131]	[153,327]	9	hSpCas9	negative selection	1770097
113226918	113226941	12	+	26627737	HCT116	viability after 8 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	3.206499269981504	[15]	[57,125,59]	9	hSpCas9	negative selection	1852407
113260453	113260476	12	+	26627737	HCT116	viability after 8 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.09852817049256102	[293]	[157,181,179]	1	hSpCas9	negative selection	1852408
113266341	113266364	12	-	26627737	HCT116	viability after 8 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	-0.208446516079432	[585]	[323,220,293]	-2	hSpCas9	negative selection	1852409
113267845	113267868	12	-	26627737	HCT116	viability after 8 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	0.23950352269597652	[278]	[231,98,213]	2	hSpCas9	negative selection	1852410
113268851	113268874	12	+	26627737	HCT116	viability after 8 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	5.492131921372248	[0]	[0,49,22]	9	hSpCas9	negative selection	1852411
113269781	113269804	12	-	26627737	HCT116	viability after 8 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	0.12320247102735715	[155]	[84,42,151]	1	hSpCas9	negative selection	1852412
113226918	113226941	12	+	26627737	HCT116	viability after 9 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	-1.0946388863562593	[139]	[26,9]	-6	hSpCas9	negative selection	1934722
113260453	113260476	12	+	26627737	HCT116	viability after 9 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.007852192414625203	[511]	[175,106]	0	hSpCas9	negative selection	1934723
113266341	113266364	12	-	26627737	HCT116	viability after 9 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.3351859405083535	[1153]	[438,348]	2	hSpCas9	negative selection	1934724
113267845	113267868	12	-	26627737	HCT116	viability after 9 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	0.4098524229662892	[519]	[303,89]	3	hSpCas9	negative selection	1934725
113268851	113268874	12	+	26627737	HCT116	viability after 9 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	0.4316498029608191	[126]	[52,39]	3	hSpCas9	negative selection	1934726
113269781	113269804	12	-	26627737	HCT116	viability after 9 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	0.6286607709942242	[131]	[44,61]	4	hSpCas9	negative selection	1934727
113226918	113226941	12	+	26627737	HCT116	viability after 12 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	2.9832780246290183	[15]	[95,29,69]	9	hSpCas9	negative selection	2017037
113260453	113260476	12	+	26627737	HCT116	viability after 12 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	-0.513082256934107	[293]	[103,59,159]	-5	hSpCas9	negative selection	2017038
113266341	113266364	12	-	26627737	HCT116	viability after 12 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.11473511987133655	[585]	[406,337,248]	1	hSpCas9	negative selection	2017039
113267845	113267868	12	-	26627737	HCT116	viability after 12 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-0.6493483640080834	[278]	[113,66,96]	-6	hSpCas9	negative selection	2017040
113268851	113268874	12	+	26627737	HCT116	viability after 12 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	4.951881269209066	[0]	[7,35,5]	9	hSpCas9	negative selection	2017041
113269781	113269804	12	-	26627737	HCT116	viability after 12 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	0.5028911107587604	[155]	[65,77,207]	5	hSpCas9	negative selection	2017042
113226918	113226941	12	+	26627737	HCT116	viability after 15 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	2.715557461405668	[15]	[122,30,34]	9	hSpCas9	negative selection	2099352
113260453	113260476	12	+	26627737	HCT116	viability after 15 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	-0.01878748347865669	[293]	[212,74,216]	0	hSpCas9	negative selection	2099353
113266341	113266364	12	-	26627737	HCT116	viability after 15 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.17629220363556686	[585]	[473,360,317]	1	hSpCas9	negative selection	2099354
113267845	113267868	12	-	26627737	HCT116	viability after 15 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	0.5659801431403132	[278]	[216,159,330]	5	hSpCas9	negative selection	2099355
113268851	113268874	12	+	26627737	HCT116	viability after 15 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	4.605389983764039	[0]	[21,13,6]	9	hSpCas9	negative selection	2099356
113269781	113269804	12	-	26627737	HCT116	viability after 15 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	0.41792223060145184	[155]	[76,83,191]	4	hSpCas9	negative selection	2099357
113226918	113226941	12	+	26627737	HCT116	viability after 18 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	2.9592289074916405	[15]	[35,56,88]	9	hSpCas9	negative selection	2181667
113260453	113260476	12	+	26627737	HCT116	viability after 18 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.2976958365852181	[293]	[227,93,208]	2	hSpCas9	negative selection	2181668
113266341	113266364	12	-	26627737	HCT116	viability after 18 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.09193398844874945	[585]	[357,208,346]	0	hSpCas9	negative selection	2181669
113267845	113267868	12	-	26627737	HCT116	viability after 18 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	0.0217957309383823	[278]	[151,111,148]	0	hSpCas9	negative selection	2181670
113268851	113268874	12	+	26627737	HCT116	viability after 18 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	4.1028211967808765	[0]	[21,1,0]	9	hSpCas9	negative selection	2181671
113269781	113269804	12	-	26627737	HCT116	viability after 18 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	0.3774804105440336	[155]	[109,40,148]	3	hSpCas9	negative selection	2181672
113266321	113266345	12	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GCCCCCGCCGTCCCCGCACTCCGG	TPCN1	ENSG00000186815	1.2114616594386505	[1038,1280,938]	[0,0,0]	4	hSpCas9	positive selection	2381513
113225265	113225290	12	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CCCAGGCTGGTCTTGAACTGCTAGG	TPCN1	ENSG00000186815	-0.4597124937400253	[3084,3930,3345]	[0,0,0]	-4	hSpCas9	positive selection	2381514
113226755	113226777	12	+	24717434	HeLa	essential genes for diphteria toxin toxicity	AGCAGCACCCCTGGCCCAGTGG	TPCN1	ENSG00000186815	-1.0163701947705115	[4504,5313,5418]	[0,0,0]	-8	hSpCas9	positive selection	2381515
113266321	113266345	12	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCCCCCGCCGTCCCCGCACTCCGG	TPCN1	ENSG00000186815	1.2105215928064768	[1038,1280,938]	[0,0,0]	3	hSpCas9	positive selection	2382950
113266321	113266345	12	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCCCCCGCCGTCCCCGCACTCCGG	TPCN1	ENSG00000186815	1.2105215928064768	[1038,1280,938]	[0,0,0]	3	hSpCas9	positive selection	2382951
113266321	113266345	12	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCCCCCGCCGTCCCCGCACTCCGG	TPCN1	ENSG00000186815	1.2105215928064768	[1038,1280,938]	[0,0,0]	3	hSpCas9	positive selection	2382952
113225265	113225290	12	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCCAGGCTGGTCTTGAACTGCTAGG	TPCN1	ENSG00000186815	3.932026147035935	[3084,3930,3345]	[0,60,0]	7	hSpCas9	positive selection	2382953
113225265	113225290	12	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCCAGGCTGGTCTTGAACTGCTAGG	TPCN1	ENSG00000186815	3.932026147035935	[3084,3930,3345]	[0,60,0]	7	hSpCas9	positive selection	2382954
113225265	113225290	12	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCCAGGCTGGTCTTGAACTGCTAGG	TPCN1	ENSG00000186815	3.932026147035935	[3084,3930,3345]	[0,60,0]	7	hSpCas9	positive selection	2382955
113226755	113226777	12	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AGCAGCACCCCTGGCCCAGTGG	TPCN1	ENSG00000186815	3.1264667239548185	[4504,5313,5418]	[0,50,0]	6	hSpCas9	positive selection	2382956
113226755	113226777	12	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AGCAGCACCCCTGGCCCAGTGG	TPCN1	ENSG00000186815	3.1264667239548185	[4504,5313,5418]	[0,50,0]	6	hSpCas9	positive selection	2382957
113226755	113226777	12	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AGCAGCACCCCTGGCCCAGTGG	TPCN1	ENSG00000186815	3.1264667239548185	[4504,5313,5418]	[0,50,0]	6	hSpCas9	positive selection	2382958
113225584	113225607	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGTCTCGCCCTGTCACCCAGG	TPCN1	ENSG00000186815	-0.4763697853295935	[174,209]	[20,39]	-2	dCas9-VP64	positive selection	2393764
113285593	113285616	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCCAACTCCTGGGCTCAAGTGG	TPCN1	ENSG00000186815	-0.6994359689071444	[220,41]	[10,22]	-4	dCas9-VP64	positive selection	2419645
113293875	113293898	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCCCAGGCTGGAGTGCAGCAG	TPCN1	ENSG00000186815	-0.49998316673352905	[290,357]	[69,28]	-2	dCas9-VP64	positive selection	2425282
113221336	113221359	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAACTATCACGTCCTTCCGCAGG	TPCN1	ENSG00000186815	4.270253865568951	[54,59]	[20,487]	9	dCas9-VP64	positive selection	2449217
113221288	113221311	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCTGCCCGCCTCCTTAAGAAGG	TPCN1	ENSG00000186815	-1.5090249872417423	[38,113]	[6,2]	-8	dCas9-VP64	positive selection	2449218
113221315	113221338	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGTCTCGCCCGCCGCCGATGCGG	TPCN1	ENSG00000186815	5.224107272456945	[56,67]	[11,1065]	9	dCas9-VP64	positive selection	2449219
113221200	113221223	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAAAGACTTGGGACTCCCTCTGG	TPCN1	ENSG00000186815	4.596994185383657	[34,36]	[20,383]	9	dCas9-VP64	positive selection	2464146
113221244	113221267	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGAACAAGGGAGGAGTAAGGG	TPCN1	ENSG00000186815	-0.5686504550626259	[485,74]	[24,57]	-3	dCas9-VP64	positive selection	2464147
113221223	113221246	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTTGGACTCAACGAGTAAGGCGG	TPCN1	ENSG00000186815	0.9471454653652225	[44,58]	[9,34]	4	dCas9-VP64	positive selection	2464148
113225584	113225607	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGTCTCGCCCTGTCACCCAGG	TPCN1	ENSG00000186815	2.3686481074679566	[489,303]	[92,1217]	9	dCas9-VP64	positive selection	2489019
113285593	113285616	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCCAACTCCTGGGCTCAAGTGG	TPCN1	ENSG00000186815	0.2833956541738802	[148,47]	[40,36]	2	dCas9-VP64	positive selection	2514900
113293875	113293898	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCCCAGGCTGGAGTGCAGCAG	TPCN1	ENSG00000186815	0.5593039216911941	[271,243]	[52,190]	4	dCas9-VP64	positive selection	2520537
113221336	113221359	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAACTATCACGTCCTTCCGCAGG	TPCN1	ENSG00000186815	1.2967468154704198	[131,153]	[50,174]	7	dCas9-VP64	positive selection	2544472
113221288	113221311	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCTGCCCGCCTCCTTAAGAAGG	TPCN1	ENSG00000186815	0.6992081766212057	[100,152]	[62,70]	5	dCas9-VP64	positive selection	2544473
113221315	113221338	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGTCTCGCCCGCCGCCGATGCGG	TPCN1	ENSG00000186815	0.36737755234715663	[77,335]	[98,73]	3	dCas9-VP64	positive selection	2544474
113221200	113221223	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAAAGACTTGGGACTCCCTCTGG	TPCN1	ENSG00000186815	0.10071608383458197	[276,148]	[96,54]	0	dCas9-VP64	positive selection	2559401
113221244	113221267	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGAACAAGGGAGGAGTAAGGG	TPCN1	ENSG00000186815	0.18333785491460208	[117,217]	[68,54]	1	dCas9-VP64	positive selection	2559402
113221223	113221246	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTTGGACTCAACGAGTAAGGCGG	TPCN1	ENSG00000186815	2.233987686549288	[33,98]	[192,15]	8	dCas9-VP64	positive selection	2559403
113269785	113269808	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGAGGATGTCCATGAAGGGCGG	TPCN1	ENSG00000186815	0.4278744907823023	[3,3]	[1,6]	8	hSpCas9	positive selection	3028719
113277015	113277038	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCGCCTGCTCATCAGCCAGAGGG	TPCN1	ENSG00000186815	0.427289656517712	[4,4]	[4,5]	8	hSpCas9	positive selection	3028720
113260454	113260477	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	-0.170677856261038	[2,3]	[2,1]	-2	hSpCas9	positive selection	3028721
113272680	113272703	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	0.0599178134149127	[4,4]	[4,3]	1	hSpCas9	positive selection	3028722
113269785	113269808	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGAGGATGTCCATGAAGGGCGG	TPCN1	ENSG00000186815	0.0025251958540727093	[3,3]	[0,2]	0	hSpCas9	positive selection	3096577
113277015	113277038	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCGCCTGCTCATCAGCCAGAGGG	TPCN1	ENSG00000186815	-0.016969826915030628	[4,4]	[4,1]	0	hSpCas9	positive selection	3096578
113260454	113260477	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.24691451356050634	[2,2]	[2,1]	4	hSpCas9	positive selection	3096579
113272680	113272703	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	0.32511869179777003	[4,4]	[4,3]	6	hSpCas9	positive selection	3096580
113260443	113260466		-	24336571	A375	resistance to PLX after 7 days	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	-0.07738909126951121	[64,51]	[56,51]	-2	hSpCas9	positive selection	3152199
113260468	113260491		-	24336571	A375	resistance to PLX after 7 days	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.04337473313959428	[20,23]	[20,23]	1	hSpCas9	positive selection	3152200
113272681	113272704		-	24336571	A375	resistance to PLX after 7 days	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	-0.30740620035742633	[12,16]	[10,12]	-8	hSpCas9	positive selection	3152201
113260443	113260466		-	24336571	A375	resistance to PLX after 14 days	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.06048150301178401	[61,56]	[24,31]	0	hSpCas9	positive selection	3209992
113260468	113260491		-	24336571	A375	resistance to PLX after 14 days	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	-0.5348940172010364	[16,26]	[7,4]	-6	hSpCas9	positive selection	3209993
113272681	113272704		-	24336571	A375	resistance to PLX after 14 days	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	-0.6955753230071683	[11,19]	[3,3]	-7	hSpCas9	positive selection	3209994
113260443	113260466		-	24336571	A375	viability after 7 days	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.2640539597349305	[50]	[64,51]	4	hSpCas9	negative selection	3267785
113260468	113260491		-	24336571	A375	viability after 7 days	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.297848698073885	[18]	[20,23]	4	hSpCas9	negative selection	3267786
113272681	113272704		-	24336571	A375	viability after 7 days	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.03236880457588051	[14]	[12,16]	0	hSpCas9	negative selection	3267787
113260443	113260466		-	24336571	A375	viability after 14 days	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.30230216345607297	[50]	[61,56]	4	hSpCas9	negative selection	3325578
113260468	113260491		-	24336571	A375	viability after 14 days	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.2928338302604541	[18]	[16,26]	4	hSpCas9	negative selection	3325579
113272681	113272704		-	24336571	A375	viability after 14 days	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.16518557385361465	[14]	[11,19]	2	hSpCas9	negative selection	3325580
113260434	113260457	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	-0.8274821763585263	[542,542]	[1,1]	-5	hSpCas9	positive selection	3398656
113273225	113273248	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-1.6099525282638267	[466,466]	[0,0]	-9	hSpCas9	positive selection	3398657
113260443	113260466	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	-0.7026757206222457	[248,248]	[0,0]	-5	hSpCas9	positive selection	3398658
113269785	113269808	12	-	26780180	HT29	viability (Avana library 4 designs)	AGGAGGATGTCCATGAAGGGCGG	TPCN1	ENSG00000186815	1.56203252479361	[]	[]	6	hSpCas9	negative selection	3467555
113277014	113277037	12	+	26780180	HT29	viability (Avana library 4 designs)	CCGCCTGCTCATCAGCCAGAGGG	TPCN1	ENSG00000186815	-0.208417275960972	[]	[]	-3	hSpCas9	negative selection	3467556
113260453	113260476	12	+	26780180	HT29	viability (Avana library 4 designs)	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.900528296194274	[]	[]	3	hSpCas9	negative selection	3467557
113272680	113272703	12	-	26780180	HT29	viability (Avana library 4 designs)	GATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	0.261853005124212	[]	[]	0	hSpCas9	negative selection	3467558
113272680	113272703	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	2.37928768012484	[]	[]	3	hSpCas9	negative selection	3571788
113277014	113277037	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCGCCTGCTCATCAGCCAGAGGG	TPCN1	ENSG00000186815	2.16874604027285	[]	[]	3	hSpCas9	negative selection	3571789
113260453	113260476	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	-0.344434436180927	[]	[]	0	hSpCas9	negative selection	3571790
113269785	113269808	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGAGGATGTCCATGAAGGGCGG	TPCN1	ENSG00000186815	3.50083427733865	[]	[]	5	hSpCas9	negative selection	3571791
113260486	113260509	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACTGGAGATACTCACCTGGAGG	TPCN1	ENSG00000186815	3.65215884044324	[]	[]	6	hSpCas9	negative selection	3571792
113267853	113267876	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATCAGGGCAAACAGCTCCAGGG	TPCN1	ENSG00000186815	4.0183769252846	[]	[]	6	hSpCas9	negative selection	3571793
113272680	113272703	12	-	26780180	A375	viability (Avana lentiGuide)	GATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	-5.20576929802574	[]	[]	-8	hSpCas9	negative selection	3680447
113277014	113277037	12	+	26780180	A375	viability (Avana lentiGuide)	CCGCCTGCTCATCAGCCAGAGGG	TPCN1	ENSG00000186815	-3.94320258652402	[]	[]	-6	hSpCas9	negative selection	3680448
113260453	113260476	12	+	26780180	A375	viability (Avana lentiGuide)	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	-5.17632352001923	[]	[]	-8	hSpCas9	negative selection	3680449
113269785	113269808	12	-	26780180	A375	viability (Avana lentiGuide)	AGGAGGATGTCCATGAAGGGCGG	TPCN1	ENSG00000186815	-1.02364219707545	[]	[]	-2	hSpCas9	negative selection	3680450
113260486	113260509	12	-	26780180	A375	viability (Avana lentiGuide)	GACTGGAGATACTCACCTGGAGG	TPCN1	ENSG00000186815	-0.928701032128967	[]	[]	-1	hSpCas9	negative selection	3680451
113267853	113267876	12	-	26780180	A375	viability (Avana lentiGuide)	CATCAGGGCAAACAGCTCCAGGG	TPCN1	ENSG00000186815	-5.09367829768449	[]	[]	-8	hSpCas9	negative selection	3680452
113272680	113272703	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	0.09961226814839375	[6]	[6,6]	2	hSpCas9	positive selection	3789054
113277014	113277037	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCGCCTGCTCATCAGCCAGAGGG	TPCN1	ENSG00000186815	0.07181112033397971	[5]	[6,5]	1	hSpCas9	positive selection	3789055
113260453	113260476	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.2890767355111696	[4]	[5,5]	8	hSpCas9	positive selection	3789056
113269785	113269808	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGAGGATGTCCATGAAGGGCGG	TPCN1	ENSG00000186815	0.1769694001321239	[4]	[4,5]	5	hSpCas9	positive selection	3789057
113260486	113260509	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACTGGAGATACTCACCTGGAGG	TPCN1	ENSG00000186815	0.2084221554539829	[5]	[6,6]	6	hSpCas9	positive selection	3789058
113267853	113267876	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCAGGGCAAACAGCTCCAGGG	TPCN1	ENSG00000186815	0.0882119405356162	[5]	[5,5]	2	hSpCas9	positive selection	3789059
113272680	113272703	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	0.19023599911204733	[6]	[6,5]	5	hSpCas9	positive selection	3897661
113277014	113277037	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCGCCTGCTCATCAGCCAGAGGG	TPCN1	ENSG00000186815	0.25979382445449206	[6]	[6,5]	7	hSpCas9	positive selection	3897662
113260453	113260476	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.22784852318767054	[4]	[4,3]	6	hSpCas9	positive selection	3897663
113269785	113269808	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGAGGATGTCCATGAAGGGCGG	TPCN1	ENSG00000186815	0.23827279314299854	[4]	[5,3]	6	hSpCas9	positive selection	3897664
113260486	113260509	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACTGGAGATACTCACCTGGAGG	TPCN1	ENSG00000186815	0.23726429187160886	[6]	[6,6]	6	hSpCas9	positive selection	3897665
113267853	113267876	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCAGGGCAAACAGCTCCAGGG	TPCN1	ENSG00000186815	0.34161359093341137	[5]	[6,5]	8	hSpCas9	positive selection	3897666
113260443	113260466	12	-	26780180	A375	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.341158061675207	[]	[]	0	hSpCas9	negative selection	4006985
113260434	113260457	12	+	26780180	A375	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.571874729158483	[]	[]	1	hSpCas9	negative selection	4006986
113273225	113273248	12	+	26780180	A375	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	2.09304708844882	[]	[]	9	hSpCas9	negative selection	4006987
113273243	113273266	12	-	26780180	A375	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	1.22570235160355	[]	[]	6	hSpCas9	negative selection	4006988
113260468	113260491	12	-	26780180	A375	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.487829815340396	[]	[]	1	hSpCas9	negative selection	4006989
113272681	113272704	12	-	26780180	A375	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.0230841084356232	[]	[]	0	hSpCas9	negative selection	4006990
113260443	113260466	12	-	26780180	HT29	viability (GeCKOv2 library)	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.706533069442958	[]	[]	2	hSpCas9	negative selection	4114951
113260434	113260457	12	+	26780180	HT29	viability (GeCKOv2 library)	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.61251017235587	[]	[]	2	hSpCas9	negative selection	4114952
113273225	113273248	12	+	26780180	HT29	viability (GeCKOv2 library)	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	1.54978368718026	[]	[]	7	hSpCas9	negative selection	4114953
113273243	113273266	12	-	26780180	HT29	viability (GeCKOv2 library)	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	1.20713738365846	[]	[]	6	hSpCas9	negative selection	4114954
113260468	113260491	12	-	26780180	HT29	viability (GeCKOv2 library)	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.545880043036376	[]	[]	1	hSpCas9	negative selection	4114955
113272681	113272704	12	-	26780180	HT29	viability (GeCKOv2 library)	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	-0.0793536523529592	[]	[]	-2	hSpCas9	negative selection	4114956
113260443	113260466	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.17629585008106885	[6]	[4,4]	4	hSpCas9	positive selection	4178733
113260468	113260491	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	-0.012222902219454213	[4]	[3,2]	0	hSpCas9	positive selection	4178734
113272681	113272704	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	-0.1818228886854643	[3]	[1,1]	-4	hSpCas9	positive selection	4178735
113260443	113260466	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.9817164540981259	[5]	[4,4,6,4]	7	hSpCas9	positive selection	4242755
113260468	113260491	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	1.2118607138973057	[3]	[4,4,3,3]	8	hSpCas9	positive selection	4242756
113272681	113272704	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	-0.9038693324057546	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4242757
113272681	113272704	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.4848389062574033	[3]	[4,4]	8	hSpCas9	positive selection	4304726
113273243	113273266	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.34022562495533765	[3]	[4,3]	7	hSpCas9	positive selection	4304727
113260468	113260491	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.32742974931588187	[3]	[4,3]	6	hSpCas9	positive selection	4304728
113260434	113260457	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.2978216016098427	[4]	[4,3]	6	hSpCas9	positive selection	4368975
113273225	113273248	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.04932333410010353	[4]	[3,2]	-1	hSpCas9	positive selection	4368976
113260443	113260466	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.22532637422171897	[3]	[3,2]	4	hSpCas9	positive selection	4368977
113267890	113267912	12	+	27760321	OCIAML3	viability	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	0.3696722053645227	[751,603]	[662,704]	4	hSpCas9	negative selection	4449424
113267925	113267947	12	-	27760321	OCIAML3	viability	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	0.0781929277215696	[1058,842]	[677,913]	0	hSpCas9	negative selection	4449425
113268849	113268871	12	+	27760321	OCIAML3	viability	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	-0.5387733794143212	[624,599]	[364,284]	-5	hSpCas9	negative selection	4449426
113272680	113272702	12	-	27760321	OCIAML3	viability	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	-0.1660348653104422	[129,120]	[80,95]	-2	hSpCas9	negative selection	4449427
113273613	113273635	12	-	27760321	OCIAML3	viability	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	0.2775882890724506	[245,206]	[186,248]	3	hSpCas9	negative selection	4449428
113267890	113267912	12	+	27760321	OCIAML2	viability	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	0.4022233081553276	[751,603]	[677,776]	5	hSpCas9	negative selection	4532887
113267925	113267947	12	-	27760321	OCIAML2	viability	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	0.12273740064228544	[1058,842]	[747,943]	1	hSpCas9	negative selection	4532888
113268849	113268871	12	+	27760321	OCIAML2	viability	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	-0.06973917617522257	[624,599]	[408,556]	-1	hSpCas9	negative selection	4532889
113272680	113272702	12	-	27760321	OCIAML2	viability	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	0.5193326127774596	[129,120]	[104,198]	7	hSpCas9	negative selection	4532890
113273613	113273635	12	-	27760321	OCIAML2	viability	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	-0.194688126665718	[245,206]	[149,171]	-2	hSpCas9	negative selection	4532891
113267890	113267912	12	+	27760321	MV411	viability	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	0.3140742066209078	[751,603]	[640,420]	2	hSpCas9	negative selection	4616350
113267925	113267947	12	-	27760321	MV411	viability	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	-0.015471740645746523	[1058,842]	[523,756]	0	hSpCas9	negative selection	4616351
113268849	113268871	12	+	27760321	MV411	viability	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	0.2649394262848624	[624,599]	[304,758]	1	hSpCas9	negative selection	4616352
113272680	113272702	12	-	27760321	MV411	viability	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	-2.2026972290333537	[129,120]	[13,23]	-8	hSpCas9	negative selection	4616353
113273613	113273635	12	-	27760321	MV411	viability	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	-1.6213941208215061	[245,206]	[43,54]	-8	hSpCas9	negative selection	4616354
113267890	113267912	12	+	27760321	HL60	viability	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	-0.3139182104259189	[751,603]	[459,424]	-4	hSpCas9	negative selection	4699813
113267925	113267947	12	-	27760321	HL60	viability	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	-0.6599292089777014	[1058,842]	[478,498]	-6	hSpCas9	negative selection	4699814
113268849	113268871	12	+	27760321	HL60	viability	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	-0.4069940056118295	[624,599]	[359,396]	-4	hSpCas9	negative selection	4699815
113272680	113272702	12	-	27760321	HL60	viability	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	0.36905243592077497	[129,120]	[80,186]	4	hSpCas9	negative selection	4699816
113273613	113273635	12	-	27760321	HL60	viability	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	-2.5340352539317093	[245,206]	[25,37]	-9	hSpCas9	negative selection	4699817
113267890	113267912	12	+	27760321	HT1080	viability	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	0.0004068836543871246	[603,471]	[264,158]	0	hSpCas9	negative selection	4783276
113267925	113267947	12	-	27760321	HT1080	viability	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	0.750204149037514	[842,657]	[331,689]	4	hSpCas9	negative selection	4783277
113268849	113268871	12	+	27760321	HT1080	viability	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	0.7886036221793092	[599,467]	[355,379]	4	hSpCas9	negative selection	4783278
113272680	113272702	12	-	27760321	HT1080	viability	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	-1.7839470728393956	[120,94]	[22,0]	-6	hSpCas9	negative selection	4783279
113273613	113273635	12	-	27760321	HT1080	viability	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	0.8723606096189053	[206,161]	[230,28]	5	hSpCas9	negative selection	4783280
113267890	113267912	12	+	27760321	HT29	viability after 7 days	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	-0.036913716581681855	[603,471]	[836,784,430]	0	hSpCas9	negative selection	4866739
113267925	113267947	12	-	27760321	HT29	viability after 7 days	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	0.26407607348858986	[842,657]	[1620,1189,742]	4	hSpCas9	negative selection	4866740
113268849	113268871	12	+	27760321	HT29	viability after 7 days	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	-0.15519208223543318	[599,467]	[624,579,643]	-2	hSpCas9	negative selection	4866741
113272680	113272702	12	-	27760321	HT29	viability after 7 days	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	-0.3588826550892119	[120,94]	[118,88,117]	-5	hSpCas9	negative selection	4866742
113273613	113273635	12	-	27760321	HT29	viability after 7 days	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	-0.619506466964105	[206,161]	[165,89,206]	-7	hSpCas9	negative selection	4866743
113267890	113267912	12	+	27760321	HT29	viability after 25 days	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	0.15661269759112806	[603,471]	[666,628,768]	1	hSpCas9	negative selection	4950202
113267925	113267947	12	-	27760321	HT29	viability after 25 days	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	-0.024561833483724094	[842,657]	[820,966,729]	0	hSpCas9	negative selection	4950203
113268849	113268871	12	+	27760321	HT29	viability after 25 days	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	0.05786622343351344	[599,467]	[593,671,641]	0	hSpCas9	negative selection	4950204
113272680	113272702	12	-	27760321	HT29	viability after 25 days	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	0.11975602315386391	[120,94]	[89,120,200]	1	hSpCas9	negative selection	4950205
113273613	113273635	12	-	27760321	HT29	viability after 25 days	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	-0.6866857736478185	[206,161]	[87,146,163]	-5	hSpCas9	negative selection	4950206
113267890	113267912	12	+	27760321	HT29	viability after 22 days	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	0.32412779432749605	[603,471]	[830,685,817]	3	hSpCas9	negative selection	5033665
113267925	113267947	12	-	27760321	HT29	viability after 22 days	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	0.22622747510273467	[842,657]	[908,1183,953]	2	hSpCas9	negative selection	5033666
113268849	113268871	12	+	27760321	HT29	viability after 22 days	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	-0.00413825104105936	[599,467]	[613,578,653]	0	hSpCas9	negative selection	5033667
113272680	113272702	12	-	27760321	HT29	viability after 22 days	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	-0.5152310365391017	[120,94]	[78,136,45]	-5	hSpCas9	negative selection	5033668
113273613	113273635	12	-	27760321	HT29	viability after 22 days	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	-0.08283412800813394	[206,161]	[233,207,160]	-1	hSpCas9	negative selection	5033669
113267890	113267912	12	+	27760321	HT29	viability after 19 days	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	0.2888958524347106	[603,471]	[905,828,543]	2	hSpCas9	negative selection	5117128
113267925	113267947	12	-	27760321	HT29	viability after 19 days	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	0.2938272233381529	[842,657]	[1610,1128,495]	2	hSpCas9	negative selection	5117129
113268849	113268871	12	+	27760321	HT29	viability after 19 days	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	0.04127682776731745	[599,467]	[800,448,651]	0	hSpCas9	negative selection	5117130
113272680	113272702	12	-	27760321	HT29	viability after 19 days	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	-0.13681299562284543	[120,94]	[190,140,16]	-1	hSpCas9	negative selection	5117131
113273613	113273635	12	-	27760321	HT29	viability after 19 days	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	-0.5955299768537152	[206,161]	[124,88,200]	-5	hSpCas9	negative selection	5117132
113267890	113267912	12	+	27760321	HT29	viability after 16 days	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	-0.14021881440973655	[603,471]	[563,439,638]	-1	hSpCas9	negative selection	5200591
113267925	113267947	12	-	27760321	HT29	viability after 16 days	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	0.3558171519964979	[842,657]	[1141,1219,863]	4	hSpCas9	negative selection	5200592
113268849	113268871	12	+	27760321	HT29	viability after 16 days	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	0.027356451140828186	[599,467]	[657,459,716]	0	hSpCas9	negative selection	5200593
113272680	113272702	12	-	27760321	HT29	viability after 16 days	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	-0.044856720034118114	[120,94]	[98,223,23]	0	hSpCas9	negative selection	5200594
113273613	113273635	12	-	27760321	HT29	viability after 16 days	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	0.1803679277205964	[206,161]	[167,370,152]	2	hSpCas9	negative selection	5200595
113267890	113267912	12	+	27760321	HT29	viability after 13 days	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	0.08289908085730102	[603,471]	[692,558,726]	1	hSpCas9	negative selection	5284054
113267925	113267947	12	-	27760321	HT29	viability after 13 days	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	0.42376813364877997	[842,657]	[1028,1478,1005]	5	hSpCas9	negative selection	5284055
113268849	113268871	12	+	27760321	HT29	viability after 13 days	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	-0.15391291449589628	[599,467]	[345,720,600]	-2	hSpCas9	negative selection	5284056
113272680	113272702	12	-	27760321	HT29	viability after 13 days	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	-0.09260230961569516	[120,94]	[148,161,45]	-1	hSpCas9	negative selection	5284057
113273613	113273635	12	-	27760321	HT29	viability after 13 days	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	-0.4473990865928903	[206,161]	[112,182,173]	-5	hSpCas9	negative selection	5284058
113267890	113267912	12	+	27760321	HT29	viability after 10 days	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	0.10046820459117367	[603,471]	[827,720,613]	1	hSpCas9	negative selection	5367517
113267925	113267947	12	-	27760321	HT29	viability after 10 days	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	0.42851622277507406	[842,657]	[1508,1607,688]	6	hSpCas9	negative selection	5367518
113268849	113268871	12	+	27760321	HT29	viability after 10 days	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	-0.027285101726380767	[599,467]	[708,598,652]	0	hSpCas9	negative selection	5367519
113272680	113272702	12	-	27760321	HT29	viability after 10 days	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	-0.6518702635923057	[120,94]	[85,154,19]	-6	hSpCas9	negative selection	5367520
113273613	113273635	12	-	27760321	HT29	viability after 10 days	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	-0.3392916884328545	[206,161]	[172,179,192]	-4	hSpCas9	negative selection	5367521
113267890	113267912	12	+	27760321	MOLM13	viability	ACTCTGCATGAAGTTACGCTGG	TPCN1	ENSG00000186815	1.0842566939668594	[751,603]	[685,908]	7	hSpCas9	negative selection	5450980
113267925	113267947	12	-	27760321	MOLM13	viability	GTCCGCTTGTGCCGGATGAAGG	TPCN1	ENSG00000186815	0.9172524464207534	[1058,842]	[930,1071]	6	hSpCas9	negative selection	5450981
113268849	113268871	12	+	27760321	MOLM13	viability	TCGGTATTGCGGTGGCGTCCGG	TPCN1	ENSG00000186815	1.2972628978797702	[624,599]	[1036,691]	8	hSpCas9	negative selection	5450982
113272680	113272702	12	-	27760321	MOLM13	viability	ATTACTTACGGGGTCTGAAGGG	TPCN1	ENSG00000186815	-1.1462995565875407	[129,120]	[31,31]	-6	hSpCas9	negative selection	5450983
113273613	113273635	12	-	27760321	MOLM13	viability	TACACGATGAAGAAGACGCAGG	TPCN1	ENSG00000186815	-1.6426182202162125	[245,206]	[63,20]	-7	hSpCas9	negative selection	5450984
113221044	113221067	12	-	27661255	K562	viability	GCGGGTAACCTAGCAACGCAGGG	TPCN1	ENSG00000186815	0.14322554229201057	[390,475]	[467,306]	5	dCas9-KRAB	negative selection	5487098
113221486	113221509	12	+	27661255	K562	viability	GGCAGTGGCTGAAGTGGCGGCGG	TPCN1	ENSG00000186815	0.6477918263821442	[687,718]	[916,847]	9	dCas9-KRAB	negative selection	5519240
113221701	113221724	12	+	27661255	K562	viability	GGGGTTGCGGCGCAGCACTCTGG	TPCN1	ENSG00000186815	-0.07243946689664338	[1129,924]	[872,706]	-3	dCas9-KRAB	negative selection	5519241
113221707	113221730	12	+	27661255	K562	viability	GCGGCGCAGCACTCTGGTGTGGG	TPCN1	ENSG00000186815	-0.07235160506130445	[251,425]	[306,210]	-3	dCas9-KRAB	negative selection	5519242
113221825	113221848	12	-	27661255	K562	viability	GGGTCGCCCTAAGAAGTCGGGGG	TPCN1	ENSG00000186815	0.08635300151299685	[1217,1469]	[1183,1094]	3	dCas9-KRAB	negative selection	5519243
113221922	113221945	12	-	27661255	K562	viability	GGCGCCAGGGAGAAGAGCGAGGG	TPCN1	ENSG00000186815	-0.08240501107468723	[458,368]	[332,296]	-3	dCas9-KRAB	negative selection	5519244
113272681	113272704	12	-	27260156	BXPC3	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.22818776831200527	[953]	[1148,1002,1250,1290]	5	hSpCas9	negative selection	5577186
113273243	113273266	12	-	27260156	BXPC3	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.39232522289772453	[758]	[936,903,1261,1084]	8	hSpCas9	negative selection	5577187
113260468	113260491	12	-	27260156	BXPC3	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.2481964729283228	[814]	[878,964,1074,1158]	5	hSpCas9	negative selection	5577188
113260434	113260457	12	+	27260156	BXPC3	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.10736501919933517	[1101]	[1157,929,1368,1569]	2	hSpCas9	negative selection	5641435
113273225	113273248	12	+	27260156	BXPC3	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.09542088752863931	[1420]	[1249,1184,1498,1684]	-2	hSpCas9	negative selection	5641436
113260443	113260466	12	-	27260156	BXPC3	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.3143273105082923	[505]	[573,717,655,687]	6	hSpCas9	negative selection	5641437
113272681	113272704	12	-	27260156	A673	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.2798554088206393	[953]	[1690,1394,1281,1217]	6	hSpCas9	negative selection	5698437
113273243	113273266	12	-	27260156	A673	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.22479087040078793	[758]	[1161,949,1048,1113]	5	hSpCas9	negative selection	5698438
113260468	113260491	12	-	27260156	A673	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.14762006394497507	[814]	[1353,844,1019,1156]	3	hSpCas9	negative selection	5698439
113260434	113260457	12	+	27260156	A673	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.22763497853320724	[1101]	[1621,1508,1581,1486]	5	hSpCas9	negative selection	5762686
113273225	113273248	12	+	27260156	A673	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.12211640120501843	[1420]	[1694,1627,1414,1542]	-3	hSpCas9	negative selection	5762687
113260443	113260466	12	-	27260156	A673	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.190857276105011	[505]	[692,714,775,580]	4	hSpCas9	negative selection	5762688
113272681	113272704	12	-	27260156	A375	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.18728366219783665	[953]	[1193,1823,1140,1017]	2	hSpCas9	negative selection	5819688
113273243	113273266	12	-	27260156	A375	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.01565573360486272	[758]	[989,1118,765,754]	0	hSpCas9	negative selection	5819689
113260468	113260491	12	-	27260156	A375	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.511724978362579	[814]	[1545,1425,1119,1343]	7	hSpCas9	negative selection	5819690
113260434	113260457	12	+	27260156	A375	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.35693986412001766	[1101]	[1488,1900,1783,1468]	5	hSpCas9	negative selection	5883937
113273225	113273248	12	+	27260156	A375	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	0.14637445183562958	[1420]	[1996,1813,1943,1610]	2	hSpCas9	negative selection	5883938
113260443	113260466	12	-	27260156	A375	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.40019503861732264	[505]	[538,1131,870,638]	6	hSpCas9	negative selection	5883939
113272681	113272704	12	-	27260156	COLO741	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.06588120435221989	[953]	[1399,1241,1198]	1	hSpCas9	negative selection	5940939
113273243	113273266	12	-	27260156	COLO741	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.08223383838231602	[758]	[1017,990,1064]	1	hSpCas9	negative selection	5940940
113260468	113260491	12	-	27260156	COLO741	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.15022219963389238	[814]	[1245,1129,1099]	3	hSpCas9	negative selection	5940941
113260434	113260457	12	+	27260156	COLO741	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.22735589234400178	[1101]	[1667,1904,1389]	5	hSpCas9	negative selection	6005188
113273225	113273248	12	+	27260156	COLO741	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.017599193758747633	[1420]	[1949,2039,1427]	0	hSpCas9	negative selection	6005189
113260443	113260466	12	-	27260156	COLO741	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.43520911144601615	[505]	[974,697,949]	8	hSpCas9	negative selection	6005190
113272681	113272704	12	-	27260156	CAL120	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	-0.11349022860320412	[953]	[1303,940,1077]	-2	hSpCas9	negative selection	6062190
113273243	113273266	12	-	27260156	CAL120	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.2069023660383974	[758]	[1094,1046,1127]	3	hSpCas9	negative selection	6062191
113260468	113260491	12	-	27260156	CAL120	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.62346648551929	[814]	[1589,1664,1437]	8	hSpCas9	negative selection	6062192
113260434	113260457	12	+	27260156	CAL120	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.5122552907988143	[1101]	[2051,1801,2025]	7	hSpCas9	negative selection	6126439
113273225	113273248	12	+	27260156	CAL120	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.38993182694436257	[1420]	[1614,1131,1340]	-5	hSpCas9	negative selection	6126440
113260443	113260466	12	-	27260156	CAL120	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.5385260015786558	[505]	[775,1283,666]	7	hSpCas9	negative selection	6126441
113272681	113272704	12	-	27260156	CADOES1	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.28472134322526244	[953]	[1316,1095,724,1188]	5	hSpCas9	negative selection	6183441
113273243	113273266	12	-	27260156	CADOES1	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.31966985963708483	[758]	[751,1165,827,774]	5	hSpCas9	negative selection	6183442
113260468	113260491	12	-	27260156	CADOES1	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.3188424976815365	[814]	[1009,826,908,1038]	5	hSpCas9	negative selection	6183443
113260434	113260457	12	+	27260156	CADOES1	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.22146695608430833	[1101]	[1432,884,1383,1071]	4	hSpCas9	negative selection	6247690
113273225	113273248	12	+	27260156	CADOES1	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.065272013348457	[1420]	[1220,1533,1017,1280]	-1	hSpCas9	negative selection	6247691
113260443	113260466	12	-	27260156	CADOES1	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.5315532978664643	[505]	[602,780,693,641]	8	hSpCas9	negative selection	6247692
113272681	113272704	12	-	27260156	EWS502	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.05772642582379084	[953]	[1032,1153,937,1075]	1	hSpCas9	negative selection	6304692
113273243	113273266	12	-	27260156	EWS502	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.3750018649800173	[758]	[907,1051,940,1297]	6	hSpCas9	negative selection	6304693
113260468	113260491	12	-	27260156	EWS502	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.30462700871152393	[814]	[934,1083,1103,1159]	5	hSpCas9	negative selection	6304694
113260434	113260457	12	+	27260156	EWS502	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.37469173899027486	[1101]	[1299,1694,1183,1910]	6	hSpCas9	negative selection	6368941
113273225	113273248	12	+	27260156	EWS502	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.020390846597835743	[1420]	[1381,1574,1384,1603]	0	hSpCas9	negative selection	6368942
113260443	113260466	12	-	27260156	EWS502	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.3835118134760718	[505]	[545,698,819,752]	6	hSpCas9	negative selection	6368943
113272681	113272704	12	-	27260156	EW8	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.04723839230691018	[953]	[1156,769,650,679]	0	hSpCas9	negative selection	6425943
113273243	113273266	12	-	27260156	EW8	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.12385172777382081	[758]	[580,629,595,873]	2	hSpCas9	negative selection	6425944
113260468	113260491	12	-	27260156	EW8	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.3425879001905938	[814]	[873,686,858,926]	6	hSpCas9	negative selection	6425945
113260434	113260457	12	+	27260156	EW8	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.1530515961175467	[1101]	[1000,1192,624,1213]	3	hSpCas9	negative selection	6490192
113273225	113273248	12	+	27260156	EW8	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.11766534378597626	[1420]	[1292,1117,923,956]	-2	hSpCas9	negative selection	6490193
113260443	113260466	12	-	27260156	EW8	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.2644938117200204	[505]	[629,470,313,598]	5	hSpCas9	negative selection	6490194
113272681	113272704	12	-	27260156	CORL105	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.13021171059478753	[953]	[1448,1055,1358,1057]	2	hSpCas9	negative selection	6547194
113273243	113273266	12	-	27260156	CORL105	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.15440642119166048	[758]	[925,944,1078,1017]	3	hSpCas9	negative selection	6547195
113260468	113260491	12	-	27260156	CORL105	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.26444691210298354	[814]	[1076,1119,1273,1130]	5	hSpCas9	negative selection	6547196
113260434	113260457	12	+	27260156	CORL105	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.3535843101906979	[1101]	[1599,1601,1736,1666]	6	hSpCas9	negative selection	6611443
113273225	113273248	12	+	27260156	CORL105	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.15082919894531766	[1420]	[1376,1491,1488,1628]	-3	hSpCas9	negative selection	6611444
113260443	113260466	12	-	27260156	CORL105	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.4972013098191218	[505]	[1005,763,949,649]	8	hSpCas9	negative selection	6611445
113272681	113272704	12	-	27260156	HS294T	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.1302881502515283	[953]	[350,400,461,404]	1	hSpCas9	negative selection	6668445
113273243	113273266	12	-	27260156	HS294T	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.19869301315201138	[758]	[238,456,320,333]	2	hSpCas9	negative selection	6668446
113260468	113260491	12	-	27260156	HS294T	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.12222141694336064	[814]	[327,368,277,406]	1	hSpCas9	negative selection	6668447
113260434	113260457	12	+	27260156	HS294T	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.7950099572499763	[1101]	[1149,432,618,719]	8	hSpCas9	negative selection	6732694
113273225	113273248	12	+	27260156	HS294T	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.2849431155273263	[1420]	[521,384,387,512]	-4	hSpCas9	negative selection	6732695
113260443	113260466	12	-	27260156	HS294T	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.37717298868428595	[505]	[283,189,330,200]	5	hSpCas9	negative selection	6732696
113272681	113272704	12	-	27260156	HCC44	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.06499351165233613	[953]	[1090,959,1514,1029]	1	hSpCas9	negative selection	6789696
113273243	113273266	12	-	27260156	HCC44	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.22672567170837088	[758]	[1035,655,1522,938]	3	hSpCas9	negative selection	6789697
113260468	113260491	12	-	27260156	HCC44	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.22689918238729856	[814]	[980,905,1174,1269]	3	hSpCas9	negative selection	6789698
113260434	113260457	12	+	27260156	HCC44	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.29482801411578996	[1101]	[1696,1626,1380,1378]	5	hSpCas9	negative selection	6853945
113273225	113273248	12	+	27260156	HCC44	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.23272854421917	[1420]	[1573,1185,1838,998]	-4	hSpCas9	negative selection	6853946
113260443	113260466	12	-	27260156	HCC44	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.5894304674481128	[505]	[584,835,1047,974]	8	hSpCas9	negative selection	6853947
113272681	113272704	12	-	27260156	G402	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.3072932817953389	[953]	[1390,1778,1442,1168]	4	hSpCas9	negative selection	6910947
113273243	113273266	12	-	27260156	G402	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	-0.017581357637348916	[758]	[883,764,1122,872]	0	hSpCas9	negative selection	6910948
113260468	113260491	12	-	27260156	G402	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.591217122385316	[814]	[1632,1273,1326,1746]	7	hSpCas9	negative selection	6910949
113260434	113260457	12	+	27260156	G402	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.2629131418116202	[1101]	[1917,1621,1464,1492]	3	hSpCas9	negative selection	6975196
113273225	113273248	12	+	27260156	G402	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	0.15555911428388902	[1420]	[1760,1788,2544,1605]	2	hSpCas9	negative selection	6975197
113260443	113260466	12	-	27260156	G402	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.4377286261217098	[505]	[415,949,856,1053]	5	hSpCas9	negative selection	6975198
113272681	113272704	12	-	27260156	L33	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.19215402321560626	[953]	[1145,470,719,918]	4	hSpCas9	negative selection	7032198
113273243	113273266	12	-	27260156	L33	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.22048047265724768	[758]	[902,417,496,822]	5	hSpCas9	negative selection	7032199
113260468	113260491	12	-	27260156	L33	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	-0.04920276548010216	[814]	[745,348,458,822]	-1	hSpCas9	negative selection	7032200
113260434	113260457	12	+	27260156	L33	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.19953277767931432	[1101]	[1238,526,761,1323]	4	hSpCas9	negative selection	7096447
113273225	113273248	12	+	27260156	L33	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.3301600441335599	[1420]	[1037,467,744,1157]	-7	hSpCas9	negative selection	7096448
113260443	113260466	12	-	27260156	L33	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.2576233219527717	[505]	[450,218,397,802]	5	hSpCas9	negative selection	7096449
113272681	113272704	12	-	27260156	K562	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.3079238916850071	[953]	[933,1285,584,1349]	4	hSpCas9	negative selection	7153449
113273243	113273266	12	-	27260156	K562	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.408686654193245	[758]	[758,1003,896,905]	5	hSpCas9	negative selection	7153450
113260468	113260491	12	-	27260156	K562	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.3099541486052546	[814]	[1081,824,1035,676]	4	hSpCas9	negative selection	7153451
113260434	113260457	12	+	27260156	K562	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.5831857846637007	[1101]	[1457,1235,1280,1823]	7	hSpCas9	negative selection	7217698
113273225	113273248	12	+	27260156	K562	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.15513096832041606	[1420]	[1184,1224,1102,1032]	-2	hSpCas9	negative selection	7217699
113260443	113260466	12	-	27260156	K562	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.5301766501465277	[505]	[376,856,604,730]	6	hSpCas9	negative selection	7217700
113272681	113272704	12	-	27260156	HT29	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.2920238793156218	[953]	[1653,1469,1376,1215]	6	hSpCas9	negative selection	7274700
113273243	113273266	12	-	27260156	HT29	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.2564165811271226	[758]	[1234,1292,1119,814]	5	hSpCas9	negative selection	7274701
113260468	113260491	12	-	27260156	HT29	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.18496815078740758	[814]	[1166,1178,1171,1001]	3	hSpCas9	negative selection	7274702
113260434	113260457	12	+	27260156	HT29	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.1967184478556756	[1101]	[1757,1517,1552,1340]	4	hSpCas9	negative selection	7338949
113273225	113273248	12	+	27260156	HT29	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	0.15661730299030996	[1420]	[1871,2139,1745,1941]	3	hSpCas9	negative selection	7338950
113260443	113260466	12	-	27260156	HT29	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.44927996527917924	[505]	[1038,996,640,719]	8	hSpCas9	negative selection	7338951
113272681	113272704	12	-	27260156	MHHES1	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.29030880018268057	[953]	[1462,1611,1116,1124]	5	hSpCas9	negative selection	7395951
113273243	113273266	12	-	27260156	MHHES1	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.17739200259194654	[758]	[1001,1056,1196,672]	3	hSpCas9	negative selection	7395952
113260468	113260491	12	-	27260156	MHHES1	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.4277504566708479	[814]	[1528,1399,1243,874]	7	hSpCas9	negative selection	7395953
113260434	113260457	12	+	27260156	MHHES1	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.17009261855095348	[1101]	[1584,1380,1194,1408]	3	hSpCas9	negative selection	7460200
113273225	113273248	12	+	27260156	MHHES1	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.02410292838496675	[1420]	[1548,1751,1798,1251]	0	hSpCas9	negative selection	7460201
113260443	113260466	12	-	27260156	MHHES1	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.24735941594916258	[505]	[518,715,674,747]	4	hSpCas9	negative selection	7460202
113272681	113272704	12	-	27260156	MEWO	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.2049341499591839	[953]	[1011,985,1084]	4	hSpCas9	negative selection	7517202
113273243	113273266	12	-	27260156	MEWO	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.28557851253907396	[758]	[849,944,797]	6	hSpCas9	negative selection	7517203
113260468	113260491	12	-	27260156	MEWO	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.06761735552033055	[814]	[1161,664,640]	1	hSpCas9	negative selection	7517204
113260434	113260457	12	+	27260156	MEWO	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.32988129014094447	[1101]	[1279,1135,1468]	7	hSpCas9	negative selection	7581451
113273225	113273248	12	+	27260156	MEWO	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.24679022943258344	[1420]	[1220,1213,944]	-5	hSpCas9	negative selection	7581452
113260443	113260466	12	-	27260156	MEWO	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.367220589564465	[505]	[861,489,528]	7	hSpCas9	negative selection	7581453
113272681	113272704	12	-	27260156	LNCAPCLONEFGC	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.1583464857132486	[953]	[946,907,1178,858]	2	hSpCas9	negative selection	7638453
113273243	113273266	12	-	27260156	LNCAPCLONEFGC	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	-0.036781147327062835	[758]	[601,781,754,547]	0	hSpCas9	negative selection	7638454
113260468	113260491	12	-	27260156	LNCAPCLONEFGC	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.5110608790934905	[814]	[858,947,1143,1280]	7	hSpCas9	negative selection	7638455
113260434	113260457	12	+	27260156	LNCAPCLONEFGC	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.48678482088763064	[1101]	[1430,1238,1516,1434]	7	hSpCas9	negative selection	7702702
113273225	113273248	12	+	27260156	LNCAPCLONEFGC	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	0.10149003567761294	[1420]	[1202,1309,1627,1426]	1	hSpCas9	negative selection	7702703
113260443	113260466	12	-	27260156	LNCAPCLONEFGC	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.6744300485965325	[505]	[680,590,839,839]	9	hSpCas9	negative selection	7702704
113272681	113272704	12	-	27260156	PANC0327	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.0973207303172734	[953]	[1050,871,722,995]	1	hSpCas9	negative selection	7759704
113273243	113273266	12	-	27260156	PANC0327	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	-0.058575786035707345	[758]	[893,426,621,694]	-1	hSpCas9	negative selection	7759705
113260468	113260491	12	-	27260156	PANC0327	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.4808479778166961	[814]	[1008,963,1042,1030]	7	hSpCas9	negative selection	7759706
113260434	113260457	12	+	27260156	PANC0327	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.2535894949752586	[1101]	[1162,941,1450,1140]	4	hSpCas9	negative selection	7823953
113273225	113273248	12	+	27260156	PANC0327	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.3199833214020893	[1420]	[1010,948,831,1259]	-5	hSpCas9	negative selection	7823954
113260443	113260466	12	-	27260156	PANC0327	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.3480587364971621	[505]	[405,462,738,680]	5	hSpCas9	negative selection	7823955
113272681	113272704	12	-	27260156	NCIH2009	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.0692702167590109	[953]	[1743,1302,1215]	0	hSpCas9	negative selection	7880955
113273243	113273266	12	-	27260156	NCIH2009	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.42279681250246437	[758]	[1637,1256,1412]	6	hSpCas9	negative selection	7880956
113260468	113260491	12	-	27260156	NCIH2009	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.2868849792861088	[814]	[1469,1179,1534]	4	hSpCas9	negative selection	7880957
113260434	113260457	12	+	27260156	NCIH2009	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.5950115684017516	[1101]	[2613,2103,2315]	7	hSpCas9	negative selection	7945204
113273225	113273248	12	+	27260156	NCIH2009	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.036441878287354346	[1420]	[2260,1742,1867]	0	hSpCas9	negative selection	7945205
113260443	113260466	12	-	27260156	NCIH2009	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.6730073961119871	[505]	[966,903,1480]	8	hSpCas9	negative selection	7945206
113272681	113272704	12	-	27260156	NCIH1373	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.24074322005710203	[953]	[1041,1852,1019,268]	2	hSpCas9	negative selection	8002206
113273243	113273266	12	-	27260156	NCIH1373	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.062171059392434946	[758]	[655,979,787,286]	0	hSpCas9	negative selection	8002207
113260468	113260491	12	-	27260156	NCIH1373	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.30186787679597504	[814]	[1080,1667,823,222]	3	hSpCas9	negative selection	8002208
113260434	113260457	12	+	27260156	NCIH1373	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.6381268726262619	[1101]	[1786,1913,1805,569]	6	hSpCas9	negative selection	8066455
113273225	113273248	12	+	27260156	NCIH1373	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.09279913622272384	[1420]	[1996,1037,893,583]	-1	hSpCas9	negative selection	8066456
113260443	113260466	12	-	27260156	NCIH1373	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.9297654366067374	[505]	[2018,636,972,228]	8	hSpCas9	negative selection	8066457
113272681	113272704	12	-	27260156	PATU8902	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.22715915711978862	[953]	[1630,1369,1289,2042]	2	hSpCas9	negative selection	8123457
113273243	113273266	12	-	27260156	PATU8902	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.019124171407021495	[758]	[937,900,735,1886]	0	hSpCas9	negative selection	8123458
113260468	113260491	12	-	27260156	PATU8902	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.4614726807978893	[814]	[1335,1789,763,2695]	5	hSpCas9	negative selection	8123459
113260434	113260457	12	+	27260156	PATU8902	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.41793370218809067	[1101]	[2093,2467,1491,2307]	4	hSpCas9	negative selection	8187706
113273225	113273248	12	+	27260156	PATU8902	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	0.3794140583500434	[1420]	[2890,2761,2467,2125]	4	hSpCas9	negative selection	8187707
113260443	113260466	12	-	27260156	PATU8902	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.8538614464872081	[505]	[1938,1446,912,815]	8	hSpCas9	negative selection	8187708
113272681	113272704	12	-	27260156	PANC1	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.41528877602685865	[953]	[891,1392,1184,969]	6	hSpCas9	negative selection	8244708
113273243	113273266	12	-	27260156	PANC1	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.30955138606597865	[758]	[874,1148,618,665]	5	hSpCas9	negative selection	8244709
113260468	113260491	12	-	27260156	PANC1	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.40956936962768364	[814]	[978,922,1135,702]	6	hSpCas9	negative selection	8244710
113260434	113260457	12	+	27260156	PANC1	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.21599008017316312	[1101]	[1018,1302,1021,1080]	3	hSpCas9	negative selection	8308957
113273225	113273248	12	+	27260156	PANC1	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.065658821753944	[1420]	[1189,1251,1156,1077]	-1	hSpCas9	negative selection	8308958
113260443	113260466	12	-	27260156	PANC1	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.5546800980941782	[505]	[596,801,727,477]	8	hSpCas9	negative selection	8308959
113272681	113272704	12	-	27260156	PANC0813	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.10536032289981123	[953]	[1335,1115,1328,1059]	1	hSpCas9	negative selection	8365959
113273243	113273266	12	-	27260156	PANC0813	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.4033820822395757	[758]	[1395,1045,1189,1106]	6	hSpCas9	negative selection	8365960
113260468	113260491	12	-	27260156	PANC0813	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.35867886173417474	[814]	[1299,1120,1230,1260]	6	hSpCas9	negative selection	8365961
113260434	113260457	12	+	27260156	PANC0813	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.33446776282301505	[1101]	[1758,1400,1720,1655]	5	hSpCas9	negative selection	8430208
113273225	113273248	12	+	27260156	PANC0813	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.1656695895452942	[1420]	[1761,1533,1348,1337]	-3	hSpCas9	negative selection	8430209
113260443	113260466	12	-	27260156	PANC0813	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.4278272204256678	[505]	[917,802,767,722]	7	hSpCas9	negative selection	8430210
113272681	113272704	12	-	27260156	RDES	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	-0.19634754894800688	[953]	[664,886,1076,1301]	-3	hSpCas9	negative selection	8487210
113273243	113273266	12	-	27260156	RDES	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.10246696561843793	[758]	[713,772,1286,1040]	1	hSpCas9	negative selection	8487211
113260468	113260491	12	-	27260156	RDES	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.35179555238022364	[814]	[842,1230,1435,1344]	5	hSpCas9	negative selection	8487212
113260434	113260457	12	+	27260156	RDES	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.34942618722561614	[1101]	[1253,1683,1721,1862]	5	hSpCas9	negative selection	8551459
113273225	113273248	12	+	27260156	RDES	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.13668684589193103	[1420]	[1096,1417,1701,1838]	-2	hSpCas9	negative selection	8551460
113260443	113260466	12	-	27260156	RDES	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.5059177448033286	[505]	[721,899,833,839]	7	hSpCas9	negative selection	8551461
113272681	113272704	12	-	27260156	PC3	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.23898294791512664	[953]	[653,1053,1952,1264]	5	hSpCas9	negative selection	8608461
113273243	113273266	12	-	27260156	PC3	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.18902426879641487	[758]	[646,914,1168,827]	4	hSpCas9	negative selection	8608462
113260468	113260491	12	-	27260156	PC3	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.2650355663681838	[814]	[517,813,1789,1240]	6	hSpCas9	negative selection	8608463
113260434	113260457	12	+	27260156	PC3	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.4340443562516749	[1101]	[993,1300,2814,1414]	8	hSpCas9	negative selection	8672710
113273225	113273248	12	+	27260156	PC3	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.2435789900709302	[1420]	[725,1350,1675,1305]	-5	hSpCas9	negative selection	8672711
113260443	113260466	12	-	27260156	PC3	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.3275300958033358	[505]	[339,654,1018,745]	7	hSpCas9	negative selection	8672712
113272681	113272704	12	-	27260156	PATU8988T	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.14354263950421076	[953]	[1195,772,899,1196]	2	hSpCas9	negative selection	8729712
113273243	113273266	12	-	27260156	PATU8988T	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.11884371148719053	[758]	[888,1010,546,758]	2	hSpCas9	negative selection	8729713
113260468	113260491	12	-	27260156	PATU8988T	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.44181039863808347	[814]	[1001,935,1143,1192]	7	hSpCas9	negative selection	8729714
113260434	113260457	12	+	27260156	PATU8988T	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.43133597940388024	[1101]	[1400,1249,1453,1636]	7	hSpCas9	negative selection	8793961
113273225	113273248	12	+	27260156	PATU8988T	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.06132099333857477	[1420]	[1311,1464,1160,1343]	-1	hSpCas9	negative selection	8793962
113260443	113260466	12	-	27260156	PATU8988T	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.16155092655991257	[505]	[665,557,499,457]	2	hSpCas9	negative selection	8793963
113272681	113272704	12	-	27260156	T47D	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.36355478802526586	[953]	[1422,1377,1464,1457]	7	hSpCas9	negative selection	8850963
113273243	113273266	12	-	27260156	T47D	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.14648787178052192	[758]	[1002,896,996,1025]	3	hSpCas9	negative selection	8850964
113260468	113260491	12	-	27260156	T47D	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.23980691062770854	[814]	[1064,1089,1073,1262]	5	hSpCas9	negative selection	8850965
113260434	113260457	12	+	27260156	T47D	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.21427934710801355	[1101]	[1458,1463,1468,1569]	4	hSpCas9	negative selection	8915212
113273225	113273248	12	+	27260156	T47D	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.16583036096823678	[1420]	[1317,1277,1476,1857]	-4	hSpCas9	negative selection	8915213
113260443	113260466	12	-	27260156	T47D	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.42335171624584356	[505]	[783,729,920,727]	8	hSpCas9	negative selection	8915214
113272681	113272704	12	-	27260156	SU8686	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.14335668298350712	[953]	[1022,908,1005,1291]	2	hSpCas9	negative selection	8972214
113273243	113273266	12	-	27260156	SU8686	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.4969669909502643	[758]	[768,930,1223,1430]	8	hSpCas9	negative selection	8972215
113260468	113260491	12	-	27260156	SU8686	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.05350404070562387	[814]	[670,743,820,1201]	0	hSpCas9	negative selection	8972216
113260434	113260457	12	+	27260156	SU8686	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.3953749611965598	[1101]	[1302,1223,1592,1708]	6	hSpCas9	negative selection	9036463
113273225	113273248	12	+	27260156	SU8686	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.07330997244550064	[1420]	[1363,1119,1347,1578]	-1	hSpCas9	negative selection	9036464
113260443	113260466	12	-	27260156	SU8686	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.4951552318801222	[505]	[579,651,795,840]	8	hSpCas9	negative selection	9036465
113272681	113272704	12	-	27260156	SKES1	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.15299071575659795	[953]	[1085,1131,883,1125]	3	hSpCas9	negative selection	9093465
113273243	113273266	12	-	27260156	SKES1	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.14108587310340392	[758]	[956,768,836,782]	3	hSpCas9	negative selection	9093466
113260468	113260491	12	-	27260156	SKES1	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.27159052773814873	[814]	[1274,957,988,757]	6	hSpCas9	negative selection	9093467
113260434	113260457	12	+	27260156	SKES1	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.13875566516937776	[1101]	[1164,1362,1210,1112]	3	hSpCas9	negative selection	9157714
113273225	113273248	12	+	27260156	SKES1	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.2938582324957102	[1420]	[1233,1324,984,1107]	-6	hSpCas9	negative selection	9157715
113260443	113260466	12	-	27260156	SKES1	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.40099123718638396	[505]	[621,777,704,571]	7	hSpCas9	negative selection	9157716
113272681	113272704	12	-	27260156	TOV112D	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.10060652119471047	[953]	[1220,1018,866,1004]	2	hSpCas9	negative selection	9214716
113273243	113273266	12	-	27260156	TOV112D	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.16462559304241975	[758]	[615,1252,777,838]	3	hSpCas9	negative selection	9214717
113260468	113260491	12	-	27260156	TOV112D	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.2838135764449694	[814]	[968,1259,1005,806]	5	hSpCas9	negative selection	9214718
113260434	113260457	12	+	27260156	TOV112D	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.24332436632294807	[1101]	[1248,1678,1054,1326]	4	hSpCas9	negative selection	9278965
113273225	113273248	12	+	27260156	TOV112D	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.10527580413899829	[1420]	[1577,1676,980,1166]	-2	hSpCas9	negative selection	9278966
113260443	113260466	12	-	27260156	TOV112D	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.2645890656147798	[505]	[799,643,516,500]	5	hSpCas9	negative selection	9278967
113272681	113272704	12	-	27260156	TC71	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.2486076503347765	[953]	[1283,1022,1185,1375]	6	hSpCas9	negative selection	9335967
113273243	113273266	12	-	27260156	TC71	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.3068824555955739	[758]	[985,847,975,1230]	7	hSpCas9	negative selection	9335968
113260468	113260491	12	-	27260156	TC71	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.21230678044605078	[814]	[896,1096,993,1066]	5	hSpCas9	negative selection	9335969
113260434	113260457	12	+	27260156	TC71	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.11857994620128709	[1101]	[1208,1271,1401,1241]	3	hSpCas9	negative selection	9400216
113273225	113273248	12	+	27260156	TC71	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.1524560914191997	[1420]	[1309,1493,1231,1456]	-4	hSpCas9	negative selection	9400217
113260443	113260466	12	-	27260156	TC71	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.1741336843662681	[505]	[629,542,599,678]	4	hSpCas9	negative selection	9400218
113272681	113272704	12	-	27260156	TC32	viability	TGATTACTTACGGGGTCTGAAGG	TPCN1	ENSG00000186815	0.16673270838610277	[953]	[830,671,1225,1451]	3	hSpCas9	negative selection	9457218
113273243	113273266	12	-	27260156	TC32	viability	GACTGACGATGCTGTTCTCCAGG	TPCN1	ENSG00000186815	0.1548290993731214	[758]	[695,700,980,830]	3	hSpCas9	negative selection	9457219
113260468	113260491	12	-	27260156	TC32	viability	GGAGGTAGATTGCTGCCTCTTGG	TPCN1	ENSG00000186815	0.3713253308802076	[814]	[1018,659,1336,1074]	6	hSpCas9	negative selection	9457220
113260434	113260457	12	+	27260156	TC32	viability	CCTCCAGCCCCGCACACAACTGG	TPCN1	ENSG00000186815	0.14500931618524038	[1101]	[956,920,1372,1424]	2	hSpCas9	negative selection	9521467
113273225	113273248	12	+	27260156	TC32	viability	CTTGCAGTACTTCAGCACCCTGG	TPCN1	ENSG00000186815	-0.0870629097474247	[1420]	[1195,696,1742,1649]	-1	hSpCas9	negative selection	9521468
113260443	113260466	12	-	27260156	TC32	viability	ATTCATCTCCCAGTTGTGTGCGG	TPCN1	ENSG00000186815	0.41827770929417596	[505]	[703,412,717,765]	7	hSpCas9	negative selection	9521469
113226918	113226941	12	+	27869803	HPAFII	viability after 27 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	-4.037086472512016	[87]	[4,0,NaN]	-9	hSpCas9	negative selection	9545312
113260453	113260476	12	+	27869803	HPAFII	viability after 27 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.5016140318283331	[260]	[202,186,NaN]	4	hSpCas9	negative selection	9545313
113266341	113266364	12	-	27869803	HPAFII	viability after 27 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.24442544661056687	[609]	[512,268,NaN]	2	hSpCas9	negative selection	9545314
113267845	113267868	12	-	27869803	HPAFII	viability after 27 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	0.6370716175913418	[159]	[114,143,NaN]	5	hSpCas9	negative selection	9545315
113268851	113268874	12	+	27869803	HPAFII	viability after 27 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	-0.6783998276145358	[43]	[8,18,NaN]	-5	hSpCas9	negative selection	9545316
113269781	113269804	12	-	27869803	HPAFII	viability after 27 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	0.5415005774856658	[138]	[65,139,NaN]	4	hSpCas9	negative selection	9545317
113226918	113226941	12	+	27869803	HPAFII	viability after 15 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	-0.31212842450002753	[87]	[180,10,NaN]	-4	hSpCas9	negative selection	9627761
113260453	113260476	12	+	27869803	HPAFII	viability after 15 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.37360867677777465	[260]	[384,349,NaN]	4	hSpCas9	negative selection	9627762
113266341	113266364	12	-	27869803	HPAFII	viability after 15 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	-0.03290858313673173	[609]	[818,529,NaN]	0	hSpCas9	negative selection	9627763
113267845	113267868	12	-	27869803	HPAFII	viability after 15 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	0.3106489547394387	[159]	[269,177,NaN]	3	hSpCas9	negative selection	9627764
113268851	113268874	12	+	27869803	HPAFII	viability after 15 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	-0.4938209257794792	[43]	[11,46,NaN]	-5	hSpCas9	negative selection	9627765
113269781	113269804	12	-	27869803	HPAFII	viability after 15 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	0.2587343399927148	[138]	[158,190,NaN]	3	hSpCas9	negative selection	9627766
113226918	113226941	12	+	27869803	ASPC1	viability after 36 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	-1.568267614244091	[177]	[65,5,0]	-8	hSpCas9	negative selection	9710210
113260453	113260476	12	+	27869803	ASPC1	viability after 36 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	-0.6518734925287127	[775]	[146,182,179]	-6	hSpCas9	negative selection	9710211
113266341	113266364	12	-	27869803	ASPC1	viability after 36 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.2208610351274275	[1079]	[412,416,470]	2	hSpCas9	negative selection	9710212
113267845	113267868	12	-	27869803	ASPC1	viability after 36 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-1.672409490009548	[531]	[159,11,22]	-9	hSpCas9	negative selection	9710213
113268851	113268874	12	+	27869803	ASPC1	viability after 36 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	1.224312920153119	[104]	[81,85,86]	9	hSpCas9	negative selection	9710214
113269781	113269804	12	-	27869803	ASPC1	viability after 36 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	1.0234994531979358	[273]	[177,313,108]	8	hSpCas9	negative selection	9710215
113226918	113226941	12	+	27869803	PATU8988S	viability after 35 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	-2.121684963866387	[248]	[41,3,NaN]	-9	hSpCas9	negative selection	9792659
113260453	113260476	12	+	27869803	PATU8988S	viability after 35 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	-0.05792151210922708	[557]	[167,263,NaN]	0	hSpCas9	negative selection	9792660
113266341	113266364	12	-	27869803	PATU8988S	viability after 35 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	0.4714384697111873	[965]	[505,572,NaN]	5	hSpCas9	negative selection	9792661
113267845	113267868	12	-	27869803	PATU8988S	viability after 35 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-0.12530223802061569	[544]	[305,95,NaN]	-1	hSpCas9	negative selection	9792662
113268851	113268874	12	+	27869803	PATU8988S	viability after 35 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	1.3247421013839975	[58]	[68,49,NaN]	9	hSpCas9	negative selection	9792663
113269781	113269804	12	-	27869803	PATU8988S	viability after 35 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	-0.3849167332799275	[252]	[92,62,NaN]	-4	hSpCas9	negative selection	9792664
113226918	113226941	12	+	27869803	PATU8988S	viability after 31 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	-2.745965262211565	[248]	[16,11,NaN]	-9	hSpCas9	negative selection	9875108
113260453	113260476	12	+	27869803	PATU8988S	viability after 31 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	-0.03877374978453677	[557]	[209,224,NaN]	0	hSpCas9	negative selection	9875109
113266341	113266364	12	-	27869803	PATU8988S	viability after 31 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	-0.005071730812784225	[965]	[356,417,NaN]	0	hSpCas9	negative selection	9875110
113267845	113267868	12	-	27869803	PATU8988S	viability after 31 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	-0.28684622341754146	[544]	[233,106,NaN]	-3	hSpCas9	negative selection	9875111
113268851	113268874	12	+	27869803	PATU8988S	viability after 31 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	1.7816533369315914	[58]	[112,39,NaN]	9	hSpCas9	negative selection	9875112
113269781	113269804	12	-	27869803	PATU8988S	viability after 31 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	-0.06731050066447342	[252]	[112,74,NaN]	0	hSpCas9	negative selection	9875113
113226918	113226941	12	+	27869803	HPAFII	viability after 35 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	-5.477343065640623	[87]	[0,0,NaN]	-9	hSpCas9	negative selection	9957557
113260453	113260476	12	+	27869803	HPAFII	viability after 35 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.6217920039477902	[260]	[136,277,NaN]	4	hSpCas9	negative selection	9957558
113266341	113266364	12	-	27869803	HPAFII	viability after 35 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	-0.5556526700306198	[609]	[171,252,NaN]	-3	hSpCas9	negative selection	9957559
113267845	113267868	12	-	27869803	HPAFII	viability after 35 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	0.4819029350290328	[159]	[122,101,NaN]	3	hSpCas9	negative selection	9957560
113268851	113268874	12	+	27869803	HPAFII	viability after 35 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	0.2705580062067394	[43]	[0,55,NaN]	1	hSpCas9	negative selection	9957561
113269781	113269804	12	-	27869803	HPAFII	viability after 35 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	0.5317101826122645	[138]	[25,186,NaN]	3	hSpCas9	negative selection	9957562
113226918	113226941	12	+	27869803	HPAFII	viability after 31 days	ACTGGCTCCCTCCAACGGCCTGG	TPCN1	ENSG00000186815	-5.626060418962039	[87]	[0,0,NaN]	-9	hSpCas9	negative selection	10040006
113260453	113260476	12	+	27869803	HPAFII	viability after 31 days	CTGGGAGATGAATTACCAAGAGG	TPCN1	ENSG00000186815	0.7147582889291965	[260]	[159,327,NaN]	5	hSpCas9	negative selection	10040007
113266341	113266364	12	-	27869803	HPAFII	viability after 31 days	CGCTCACATAGATGCCAAGCCGG	TPCN1	ENSG00000186815	-0.0894018141679267	[609]	[338,302,NaN]	0	hSpCas9	negative selection	10040008
113267845	113267868	12	-	27869803	HPAFII	viability after 31 days	CAAACAGCTCCAGGGTGGCGTGG	TPCN1	ENSG00000186815	0.7680224884843899	[159]	[150,154,NaN]	5	hSpCas9	negative selection	10040009
113268851	113268874	12	+	27869803	HPAFII	viability after 31 days	GGTATTGCGGTGGCGTCCGGCGG	TPCN1	ENSG00000186815	-1.5121694524340552	[43]	[0,16,NaN]	-7	hSpCas9	negative selection	10040010
113269781	113269804	12	-	27869803	HPAFII	viability after 31 days	GGATGTCCATGAAGGGCGGCAGG	TPCN1	ENSG00000186815	0.3316614311452474	[138]	[34,166,NaN]	2	hSpCas9	negative selection	10040011
113266197	113266220	12	+	28162770	P31FUJ	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	0.1626474894950671	[240]	[316]	1	hSpCas9	negative selection	10255626
113266283	113266306	12	-	28162770	P31FUJ	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	-0.1705179261600358	[67]	[70]	-2	hSpCas9	negative selection	10255627
113266209	113266232	12	-	28162770	P31FUJ	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-1.3108047164156515	[94]	[44]	-7	hSpCas9	negative selection	10255628
113267857	113267880	12	+	28162770	P31FUJ	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	0.3854803695068042	[427]	[656]	4	hSpCas9	negative selection	10255629
113268841	113268864	12	+	28162770	P31FUJ	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	0.8678917952050943	[82]	[177]	8	hSpCas9	negative selection	10255630
113285878	113285901	12	+	28162770	P31FUJ	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	0.9234534935568287	[270]	[603]	9	hSpCas9	negative selection	10255631
113288796	113288819	12	-	28162770	P31FUJ	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	0.0064887414954376554	[193]	[228]	0	hSpCas9	negative selection	10255632
113290152	113290175	12	+	28162770	P31FUJ	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	0.07330092331130117	[274]	[339]	0	hSpCas9	negative selection	10255633
113290173	113290196	12	+	28162770	P31FUJ	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	0.7437388227616326	[92]	[182]	8	hSpCas9	negative selection	10255634
113226893	113226916	12	-	28162770	P31FUJ	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	0.18386638044339332	[662]	[884]	2	hSpCas9	negative selection	10255635
113266197	113266220	12	+	28162770	TF1	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	NaN	[NaN]	[359]	1	hSpCas9	negative selection	10424992
113266283	113266306	12	-	28162770	TF1	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	NaN	[NaN]	[107]	1	hSpCas9	negative selection	10424993
113266209	113266232	12	-	28162770	TF1	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10424994
113267857	113267880	12	+	28162770	TF1	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	NaN	[NaN]	[181]	1	hSpCas9	negative selection	10424995
113268841	113268864	12	+	28162770	TF1	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10424996
113285878	113285901	12	+	28162770	TF1	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	NaN	[NaN]	[235]	1	hSpCas9	negative selection	10424997
113288796	113288819	12	-	28162770	TF1	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	NaN	[NaN]	[141]	1	hSpCas9	negative selection	10424998
113290152	113290175	12	+	28162770	TF1	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	NaN	[NaN]	[250]	1	hSpCas9	negative selection	10424999
113290173	113290196	12	+	28162770	TF1	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10425000
113226893	113226916	12	-	28162770	TF1	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	NaN	[NaN]	[645]	1	hSpCas9	negative selection	10425001
113266197	113266220	12	+	28162770	SKM1	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	-0.8006280472294385	[66]	[67]	-5	hSpCas9	negative selection	10594358
113266283	113266306	12	-	28162770	SKM1	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	0.4093238480844501	[22]	[53]	4	hSpCas9	negative selection	10594359
113266209	113266232	12	-	28162770	SKM1	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-1.1532076064973786	[38]	[30]	-7	hSpCas9	negative selection	10594360
113267857	113267880	12	+	28162770	SKM1	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	-0.19751083311421214	[143]	[221]	-2	hSpCas9	negative selection	10594361
113268841	113268864	12	+	28162770	SKM1	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	-1.4069641987431618	[32]	[21]	-7	hSpCas9	negative selection	10594362
113285878	113285901	12	+	28162770	SKM1	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	-0.04980761554481783	[88]	[151]	0	hSpCas9	negative selection	10594363
113288796	113288819	12	-	28162770	SKM1	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	-0.8220016980220053	[33]	[33]	-6	hSpCas9	negative selection	10594364
113290152	113290175	12	+	28162770	SKM1	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	0.29829253569570646	[45]	[99]	3	hSpCas9	negative selection	10594365
113290173	113290196	12	+	28162770	SKM1	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	0.09553614178602143	[17]	[33]	0	hSpCas9	negative selection	10594366
113226893	113226916	12	-	28162770	SKM1	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	0.42397754363205853	[155]	[369]	4	hSpCas9	negative selection	10594367
113266197	113266220	12	+	28162770	SKM1	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	-0.8006280472294385	[66]	[67]	-5	hSpCas9	negative selection	10763724
113266283	113266306	12	-	28162770	SKM1	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	0.4093238480844501	[22]	[53]	4	hSpCas9	negative selection	10763725
113266209	113266232	12	-	28162770	SKM1	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-1.1532076064973786	[38]	[30]	-7	hSpCas9	negative selection	10763726
113267857	113267880	12	+	28162770	SKM1	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	-0.19751083311421214	[143]	[221]	-2	hSpCas9	negative selection	10763727
113268841	113268864	12	+	28162770	SKM1	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	-1.4069641987431618	[32]	[21]	-7	hSpCas9	negative selection	10763728
113285878	113285901	12	+	28162770	SKM1	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	-0.04980761554481783	[88]	[151]	0	hSpCas9	negative selection	10763729
113288796	113288819	12	-	28162770	SKM1	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	-0.8220016980220053	[33]	[33]	-6	hSpCas9	negative selection	10763730
113290152	113290175	12	+	28162770	SKM1	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	0.29829253569570646	[45]	[99]	3	hSpCas9	negative selection	10763731
113290173	113290196	12	+	28162770	SKM1	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	0.09553614178602143	[17]	[33]	0	hSpCas9	negative selection	10763732
113226893	113226916	12	-	28162770	SKM1	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	0.42397754363205853	[155]	[369]	4	hSpCas9	negative selection	10763733
113266197	113266220	12	+	28162770	PL21	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	-0.607215307568284	[244]	[69]	-4	hSpCas9	negative selection	10933090
113266283	113266306	12	-	28162770	PL21	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	0.3020192285085339	[40]	[21]	2	hSpCas9	negative selection	10933091
113266209	113266232	12	-	28162770	PL21	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-0.2225514573329589	[125]	[46]	-2	hSpCas9	negative selection	10933092
113267857	113267880	12	+	28162770	PL21	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	-0.9074593851778343	[486]	[112]	-6	hSpCas9	negative selection	10933093
113268841	113268864	12	+	28162770	PL21	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	-1.1079826808730118	[103]	[20]	-6	hSpCas9	negative selection	10933094
113285878	113285901	12	+	28162770	PL21	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	-0.6743295034268209	[362]	[98]	-5	hSpCas9	negative selection	10933095
113288796	113288819	12	-	28162770	PL21	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	0.2001396144893201	[171]	[85]	1	hSpCas9	negative selection	10933096
113290152	113290175	12	+	28162770	PL21	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	-0.3519582523262095	[216]	[73]	-3	hSpCas9	negative selection	10933097
113290173	113290196	12	+	28162770	PL21	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	-0.18233002233309326	[72]	[27]	-1	hSpCas9	negative selection	10933098
113226893	113226916	12	-	28162770	PL21	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	0.8363045678680343	[488]	[379]	7	hSpCas9	negative selection	10933099
113266197	113266220	12	+	28162770	P31FUJ	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	0.1626474894950671	[240]	[316]	1	hSpCas9	negative selection	11102456
113266283	113266306	12	-	28162770	P31FUJ	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	-0.1705179261600358	[67]	[70]	-2	hSpCas9	negative selection	11102457
113266209	113266232	12	-	28162770	P31FUJ	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-1.3108047164156515	[94]	[44]	-7	hSpCas9	negative selection	11102458
113267857	113267880	12	+	28162770	P31FUJ	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	0.3854803695068042	[427]	[656]	4	hSpCas9	negative selection	11102459
113268841	113268864	12	+	28162770	P31FUJ	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	0.8678917952050943	[82]	[177]	8	hSpCas9	negative selection	11102460
113285878	113285901	12	+	28162770	P31FUJ	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	0.9234534935568287	[270]	[603]	9	hSpCas9	negative selection	11102461
113288796	113288819	12	-	28162770	P31FUJ	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	0.0064887414954376554	[193]	[228]	0	hSpCas9	negative selection	11102462
113290152	113290175	12	+	28162770	P31FUJ	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	0.07330092331130117	[274]	[339]	0	hSpCas9	negative selection	11102463
113290173	113290196	12	+	28162770	P31FUJ	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	0.7437388227616326	[92]	[182]	8	hSpCas9	negative selection	11102464
113226893	113226916	12	-	28162770	P31FUJ	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	0.18386638044339332	[662]	[884]	2	hSpCas9	negative selection	11102465
113266197	113266220	12	+	28162770	OCIAML5	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	0.17863022635891945	[92]	[189]	1	hSpCas9	negative selection	11271822
113266283	113266306	12	-	28162770	OCIAML5	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	-0.5790480764575809	[23]	[28]	-4	hSpCas9	negative selection	11271823
113266209	113266232	12	-	28162770	OCIAML5	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-2.39955436616649	[75]	[25]	-8	hSpCas9	negative selection	11271824
113267857	113267880	12	+	28162770	OCIAML5	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	0.7122364592910664	[210]	[623]	6	hSpCas9	negative selection	11271825
113268841	113268864	12	+	28162770	OCIAML5	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	-0.05851744833142336	[59]	[103]	0	hSpCas9	negative selection	11271826
113285878	113285901	12	+	28162770	OCIAML5	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	0.21402261959377522	[191]	[401]	1	hSpCas9	negative selection	11271827
113288796	113288819	12	-	28162770	OCIAML5	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	0.8713099585542539	[95]	[316]	7	hSpCas9	negative selection	11271828
113290152	113290175	12	+	28162770	OCIAML5	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	0.33277310458959863	[138]	[315]	3	hSpCas9	negative selection	11271829
113290173	113290196	12	+	28162770	OCIAML5	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	0.20588077834528262	[60]	[126]	1	hSpCas9	negative selection	11271830
113226893	113226916	12	-	28162770	OCIAML5	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	0.22573070676167006	[369]	[780]	1	hSpCas9	negative selection	11271831
113266197	113266220	12	+	28162770	EOL1	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	0.6851646338013859	[483]	[409]	6	hSpCas9	negative selection	11441188
113266283	113266306	12	-	28162770	EOL1	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	-0.3384866342632593	[71]	[29]	-3	hSpCas9	negative selection	11441189
113266209	113266232	12	-	28162770	EOL1	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-0.36823397765731136	[195]	[79]	-3	hSpCas9	negative selection	11441190
113267857	113267880	12	+	28162770	EOL1	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	0.12329304904934824	[825]	[473]	1	hSpCas9	negative selection	11441191
113268841	113268864	12	+	28162770	EOL1	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	0.8562417581796257	[172]	[164]	7	hSpCas9	negative selection	11441192
113285878	113285901	12	+	28162770	EOL1	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	0.888542818115041	[567]	[553]	7	hSpCas9	negative selection	11441193
113288796	113288819	12	-	28162770	EOL1	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	0.8260579081711711	[196]	[183]	7	hSpCas9	negative selection	11441194
113290152	113290175	12	+	28162770	EOL1	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	0.35873032011608175	[261]	[176]	3	hSpCas9	negative selection	11441195
113290173	113290196	12	+	28162770	EOL1	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	-2.0203106742370047	[76]	[9]	-8	hSpCas9	negative selection	11441196
113226893	113226916	12	-	28162770	EOL1	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	-0.16432097692852365	[769]	[361]	-1	hSpCas9	negative selection	11441197
113266197	113266220	12	+	28162770	MOLM13	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	0.5518677741839318	[316]	[335]	4	hSpCas9	negative selection	11610554
113266283	113266306	12	-	28162770	MOLM13	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	-3.661393635400388	[34]	[1]	-9	hSpCas9	negative selection	11610555
113266209	113266232	12	-	28162770	MOLM13	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	0.24549696020813083	[146]	[125]	1	hSpCas9	negative selection	11610556
113267857	113267880	12	+	28162770	MOLM13	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	0.8740252525066612	[568]	[753]	6	hSpCas9	negative selection	11610557
113268841	113268864	12	+	28162770	MOLM13	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	0.23776959818352017	[155]	[132]	1	hSpCas9	negative selection	11610558
113285878	113285901	12	+	28162770	MOLM13	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	0.9642269829252706	[413]	[583]	7	hSpCas9	negative selection	11610559
113288796	113288819	12	-	28162770	MOLM13	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	0.09714115841053154	[277]	[214]	0	hSpCas9	negative selection	11610560
113290152	113290175	12	+	28162770	MOLM13	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	-0.09646283950129131	[277]	[187]	0	hSpCas9	negative selection	11610561
113290173	113290196	12	+	28162770	MOLM13	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	-0.20701524448937603	[90]	[56]	-1	hSpCas9	negative selection	11610562
113226893	113226916	12	-	28162770	MOLM13	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	0.1929587661943859	[754]	[623]	1	hSpCas9	negative selection	11610563
113266197	113266220	12	+	28162770	HEL	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	0.1288594293406834	[296]	[207]	1	hSpCas9	negative selection	11779920
113266283	113266306	12	-	28162770	HEL	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	1.693364905070325	[27]	[57]	9	hSpCas9	negative selection	11779921
113266209	113266232	12	-	28162770	HEL	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-0.49476469174957804	[153]	[69]	-3	hSpCas9	negative selection	11779922
113267857	113267880	12	+	28162770	HEL	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	0.38229222065571866	[556]	[464]	3	hSpCas9	negative selection	11779923
113268841	113268864	12	+	28162770	HEL	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	0.9720464572533168	[116]	[146]	8	hSpCas9	negative selection	11779924
113285878	113285901	12	+	28162770	HEL	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	-0.16971696175011264	[424]	[241]	-1	hSpCas9	negative selection	11779925
113288796	113288819	12	-	28162770	HEL	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	-1.6653834633619748	[207]	[41]	-7	hSpCas9	negative selection	11779926
113290152	113290175	12	+	28162770	HEL	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	1.6095719680651577	[175]	[343]	9	hSpCas9	negative selection	11779927
113290173	113290196	12	+	28162770	HEL	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	-0.17892392674113067	[75]	[42]	-1	hSpCas9	negative selection	11779928
113226893	113226916	12	-	28162770	HEL	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	0.0798558647501193	[615]	[416]	0	hSpCas9	negative selection	11779929
113266197	113266220	12	+	28162770	MV411	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	0.07831027954651643	[225]	[200]	0	hSpCas9	negative selection	11949286
113266283	113266306	12	-	28162770	MV411	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	2.4364713751727924	[24]	[113]	9	hSpCas9	negative selection	11949287
113266209	113266232	12	-	28162770	MV411	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	0.26238789224874703	[95]	[96]	2	hSpCas9	negative selection	11949288
113267857	113267880	12	+	28162770	MV411	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	0.10322380544328791	[430]	[389]	0	hSpCas9	negative selection	11949289
113268841	113268864	12	+	28162770	MV411	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	0.7307597896280938	[97]	[136]	6	hSpCas9	negative selection	11949290
113285878	113285901	12	+	28162770	MV411	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	0.3803763826009035	[258]	[283]	3	hSpCas9	negative selection	11949291
113288796	113288819	12	-	28162770	MV411	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	-0.9533814586053209	[176]	[76]	-6	hSpCas9	negative selection	11949292
113290152	113290175	12	+	28162770	MV411	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	0.8200163270480992	[155]	[231]	7	hSpCas9	negative selection	11949293
113290173	113290196	12	+	28162770	MV411	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	1.669264215724258	[52]	[141]	9	hSpCas9	negative selection	11949294
113226893	113226916	12	-	28162770	MV411	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	0.41454753661803356	[512]	[575]	3	hSpCas9	negative selection	11949295
113266197	113266220	12	+	28162770	MONOMAC1	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	0.4094817970280499	[154]	[235]	4	hSpCas9	negative selection	12118652
113266283	113266306	12	-	28162770	MONOMAC1	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	0.8276252071747152	[28]	[58]	7	hSpCas9	negative selection	12118653
113266209	113266232	12	-	28162770	MONOMAC1	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-0.3173310807772656	[74]	[68]	-3	hSpCas9	negative selection	12118654
113267857	113267880	12	+	28162770	MONOMAC1	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	0.529281502907144	[271]	[449]	5	hSpCas9	negative selection	12118655
113268841	113268864	12	+	28162770	MONOMAC1	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	1.6403128152958877	[67]	[242]	9	hSpCas9	negative selection	12118656
113285878	113285901	12	+	28162770	MONOMAC1	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	-0.5298415311975218	[232]	[184]	-4	hSpCas9	negative selection	12118657
113288796	113288819	12	-	28162770	MONOMAC1	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	-0.7221278918033114	[117]	[81]	-5	hSpCas9	negative selection	12118658
113290152	113290175	12	+	28162770	MONOMAC1	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	-0.20997590276705172	[111]	[110]	-2	hSpCas9	negative selection	12118659
113290173	113290196	12	+	28162770	MONOMAC1	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	1.196627001426723	[50]	[133]	9	hSpCas9	negative selection	12118660
113226893	113226916	12	-	28162770	MONOMAC1	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	-0.1927998541730831	[339]	[340]	-2	hSpCas9	negative selection	12118661
113266197	113266220	12	+	28162770	OCIAML2	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	0.4650491937909822	[42]	[328]	4	hSpCas9	negative selection	12288018
113266283	113266306	12	-	28162770	OCIAML2	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	2.5066500982577553	[1]	[62]	9	hSpCas9	negative selection	12288019
113266209	113266232	12	-	28162770	OCIAML2	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-1.8076648125197319	[23]	[37]	-8	hSpCas9	negative selection	12288020
113267857	113267880	12	+	28162770	OCIAML2	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	0.7417304425205479	[66]	[620]	7	hSpCas9	negative selection	12288021
113268841	113268864	12	+	28162770	OCIAML2	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	0.17322636453256368	[19]	[124]	1	hSpCas9	negative selection	12288022
113285878	113285901	12	+	28162770	OCIAML2	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	0.9411837731623963	[55]	[595]	8	hSpCas9	negative selection	12288023
113288796	113288819	12	-	28162770	OCIAML2	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	-0.9770903522845996	[37]	[106]	-6	hSpCas9	negative selection	12288024
113290152	113290175	12	+	28162770	OCIAML2	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	-0.788805785268416	[47]	[153]	-5	hSpCas9	negative selection	12288025
113290173	113290196	12	+	28162770	OCIAML2	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	-0.023170848270939848	[10]	[59]	0	hSpCas9	negative selection	12288026
113226893	113226916	12	-	28162770	OCIAML2	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	-0.42659705717949503	[120]	[498]	-3	hSpCas9	negative selection	12288027
113266197	113266220	12	+	28162770	OCIAML3	viability	CAAGTTCTTCACCCACCCCAAGG	TPCN1	ENSG00000186815	-0.4355782777196802	[55]	[124]	-3	hSpCas9	negative selection	12457384
113266283	113266306	12	-	28162770	OCIAML3	viability	CAGCAGCAGCAGCAGGGCCGTGG	TPCN1	ENSG00000186815	-1.009045139603007	[13]	[20]	-6	hSpCas9	negative selection	12457385
113266209	113266232	12	-	28162770	OCIAML3	viability	GCGCCTTGGCATCCTTGGGGTGG	TPCN1	ENSG00000186815	-2.3440293873158153	[36]	[21]	-9	hSpCas9	negative selection	12457386
113267857	113267880	12	+	28162770	OCIAML3	viability	GGAGCTGTTTGCCCTGATGGTGG	TPCN1	ENSG00000186815	-1.6918549637223077	[121]	[113]	-8	hSpCas9	negative selection	12457387
113268841	113268864	12	+	28162770	OCIAML3	viability	GTGGACTGTCGGTATTGCGGTGG	TPCN1	ENSG00000186815	-0.029223021540637495	[23]	[70]	0	hSpCas9	negative selection	12457388
113285878	113285901	12	+	28162770	OCIAML3	viability	TCTGTCCACAGTCTATGGGGTGG	TPCN1	ENSG00000186815	0.17651051355306951	[67]	[231]	1	hSpCas9	negative selection	12457389
113288796	113288819	12	-	28162770	OCIAML3	viability	GAAGAACTCCATGCCCACGATGG	TPCN1	ENSG00000186815	-0.7195385224080222	[41]	[76]	-5	hSpCas9	negative selection	12457390
113290152	113290175	12	+	28162770	OCIAML3	viability	CCGCTGGCGCAACCACACCGTGG	TPCN1	ENSG00000186815	0.9656881017865631	[47]	[282]	8	hSpCas9	negative selection	12457391
113290173	113290196	12	+	28162770	OCIAML3	viability	GGGCAACAGGACCGTGGTGGAGG	TPCN1	ENSG00000186815	0.643031556976686	[20]	[98]	6	hSpCas9	negative selection	12457392
113226893	113226916	12	-	28162770	OCIAML3	viability	GGCACTGCCACCCTCATCCAAGG	TPCN1	ENSG00000186815	-0.41276732565401664	[126]	[287]	-3	hSpCas9	negative selection	12457393