Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 10626
• Symbol: TRIM16
• Description: tripartite motif containing 16

DataSource: http://genomecrispr.dkfz.de/#!/results/TRIM16

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
15651441	15651464	17	-	26472758	Jiyoye	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	0.5258198780044925	[139]	[151]	4	hSpCas9	negative selection	172028
15651532	15651555	17	+	26472758	Jiyoye	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	2.257599025455363	[32]	[118]	9	hSpCas9	negative selection	172029
15636242	15636265	17	-	26472758	Jiyoye	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	0.4306343543298623	[60]	[61]	3	hSpCas9	negative selection	172030
15651412	15651435	17	-	26472758	Jiyoye	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	1.0015365802292793	[50]	[76]	6	hSpCas9	negative selection	172031
15651557	15651580	17	+	26472758	Jiyoye	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-1.2557896312165557	[37]	[11]	-7	hSpCas9	negative selection	172032
15651499	15651522	17	+	26472758	Jiyoye	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	0.2709096914147924	[232]	[211]	2	hSpCas9	negative selection	172033
15651473	15651496	17	-	26472758	Jiyoye	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-0.44214570599645836	[217]	[120]	-3	hSpCas9	negative selection	172034
15651345	15651368	17	-	26472758	Jiyoye	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	-0.35835936485710373	[322]	[189]	-3	hSpCas9	negative selection	172035
15651240	15651263	17	+	26472758	Jiyoye	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	4.930737337562886	[0]	[22]	9	hSpCas9	negative selection	172036
15651179	15651202	17	+	26472758	Jiyoye	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	1.2145303035634778	[39]	[69]	7	hSpCas9	negative selection	172037
15651441	15651464	17	-	26472758	KBM7	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	-0.6190194392082766	[839,571]	[231,195]	-5	hSpCas9	negative selection	363146
15651532	15651555	17	+	26472758	KBM7	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	0.7282580668935366	[390,568]	[178,564]	7	hSpCas9	negative selection	363147
15636242	15636265	17	-	26472758	KBM7	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	0.7140237519605702	[381,232]	[308,163]	7	hSpCas9	negative selection	363148
15651412	15651435	17	-	26472758	KBM7	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	0.02351981072833631	[365,214]	[176,98]	0	hSpCas9	negative selection	363149
15651557	15651580	17	+	26472758	KBM7	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	0.22677244936309182	[102,110]	[70,48]	2	hSpCas9	negative selection	363150
15651499	15651522	17	+	26472758	KBM7	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	0.041067418278542656	[1021,546]	[461,286]	0	hSpCas9	negative selection	363151
15651473	15651496	17	-	26472758	KBM7	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-0.4147716640512229	[1060,956]	[322,384]	-4	hSpCas9	negative selection	363152
15651345	15651368	17	-	26472758	KBM7	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	0.38536676468820996	[1183,1154]	[874,582]	4	hSpCas9	negative selection	363153
15651240	15651263	17	+	26472758	KBM7	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	0.389826380400753	[273,736]	[279,369]	4	hSpCas9	negative selection	363154
15651179	15651202	17	+	26472758	KBM7	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	0.13059680286300668	[289,190]	[87,151]	1	hSpCas9	negative selection	363155
15651441	15651464	17	-	26472758	Raji	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	0.33919921059667313	[217]	[63]	3	hSpCas9	negative selection	554264
15651532	15651555	17	+	26472758	Raji	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	-0.5201035819941138	[240]	[38]	-4	hSpCas9	negative selection	554265
15636242	15636265	17	-	26472758	Raji	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	0.1931134093994833	[97]	[25]	1	hSpCas9	negative selection	554266
15651412	15651435	17	-	26472758	Raji	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	1.44441852265117	[94]	[59]	9	hSpCas9	negative selection	554267
15651557	15651580	17	+	26472758	Raji	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-0.8622428155828816	[93]	[11]	-6	hSpCas9	negative selection	554268
15651499	15651522	17	+	26472758	Raji	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	0.49655897134047744	[393]	[128]	5	hSpCas9	negative selection	554269
15651473	15651496	17	-	26472758	Raji	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-1.7878015595826402	[490]	[32]	-8	hSpCas9	negative selection	554270
15651345	15651368	17	-	26472758	Raji	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	-0.5070980522676118	[789]	[128]	-4	hSpCas9	negative selection	554271
15651240	15651263	17	+	26472758	Raji	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	-0.29254707151503595	[189]	[35]	-2	hSpCas9	negative selection	554272
15651179	15651202	17	+	26472758	Raji	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-0.49252930681352836	[96]	[15]	-4	hSpCas9	negative selection	554273
15651441	15651464	17	-	26472758	K562	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	-0.3809015106708503	[434]	[281]	-3	hSpCas9	negative selection	745382
15651532	15651555	17	+	26472758	K562	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	0.10611570539735948	[360]	[327]	0	hSpCas9	negative selection	745383
15636242	15636265	17	-	26472758	K562	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	0.31201680581725727	[270]	[283]	2	hSpCas9	negative selection	745384
15651412	15651435	17	-	26472758	K562	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	-0.022226931719726006	[319]	[265]	0	hSpCas9	negative selection	745385
15651557	15651580	17	+	26472758	K562	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-0.7555812723335529	[59]	[29]	-4	hSpCas9	negative selection	745386
15651499	15651522	17	+	26472758	K562	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	0.673105288457142	[525]	[707]	5	hSpCas9	negative selection	745387
15651473	15651496	17	-	26472758	K562	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-0.29700488819927195	[766]	[526]	-2	hSpCas9	negative selection	745388
15651345	15651368	17	-	26472758	K562	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	0.7741723858837151	[1020]	[1473]	6	hSpCas9	negative selection	745389
15651240	15651263	17	+	26472758	K562	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	0.17041814622267026	[199]	[189]	1	hSpCas9	negative selection	745390
15651179	15651202	17	+	26472758	K562	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-2.277349946567515	[200]	[34]	-7	hSpCas9	negative selection	745391
15651413	15651436	17	-	26627737	DLD1	viability	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	0.949820721296744	[89]	[83,36,42]	8	hSpCas9	negative selection	796222
15651414	15651437	17	-	26627737	DLD1	viability	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-1.0475496465451006	[308]	[53,39,45]	-7	hSpCas9	negative selection	796223
15651489	15651512	17	-	26627737	DLD1	viability	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.7884816644229635	[504]	[134,73,67]	-6	hSpCas9	negative selection	796224
15651413	15651436	17	-	26627737	GBM cells	viability after 5 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-0.12155022767403012	[70]	[17,51]	-2	hSpCas9	negative selection	878537
15651414	15651437	17	-	26627737	GBM cells	viability after 5 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-0.5685910442872937	[111]	[37,42]	-7	hSpCas9	negative selection	878538
15651489	15651512	17	-	26627737	GBM cells	viability after 5 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.005605816260086105	[189]	[115,86]	0	hSpCas9	negative selection	878539
15651413	15651436	17	-	26627737	GBM cells	viability after 13 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-1.4221539449818592	[70]	[4,21]	-9	hSpCas9	negative selection	960852
15651414	15651437	17	-	26627737	GBM cells	viability after 13 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	0.13098743712843408	[111]	[49,79]	1	hSpCas9	negative selection	960853
15651489	15651512	17	-	26627737	GBM cells	viability after 13 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.08630939539012639	[189]	[95,97]	-1	hSpCas9	negative selection	960854
15651413	15651436	17	-	26627737	GBM cells	viability after 21 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-0.540384065136922	[70]	[25,26]	-5	hSpCas9	negative selection	1043167
15651414	15651437	17	-	26627737	GBM cells	viability after 21 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	0.7260021052784914	[111]	[108,92]	7	hSpCas9	negative selection	1043168
15651489	15651512	17	-	26627737	GBM cells	viability after 21 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.5496162777621845	[189]	[69,70]	-5	hSpCas9	negative selection	1043169
15651413	15651436	17	-	26627737	RPE1	viability after 9 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-1.272091961833552	[981]	[87,177]	-7	hSpCas9	negative selection	1125482
15651414	15651437	17	-	26627737	RPE1	viability after 9 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-1.2174420985693413	[872]	[165,54]	-7	hSpCas9	negative selection	1125483
15651489	15651512	17	-	26627737	RPE1	viability after 9 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.34635706427906376	[319]	[91,172]	2	hSpCas9	negative selection	1125484
15651413	15651436	17	-	26627737	RPE1	viability after 12 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-2.6649561793878256	[981]	[10,73]	-9	hSpCas9	negative selection	1207797
15651414	15651437	17	-	26627737	RPE1	viability after 12 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-1.4096183261095319	[872]	[148,23]	-7	hSpCas9	negative selection	1207798
15651489	15651512	17	-	26627737	RPE1	viability after 12 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.3696047759483245	[319]	[50,82]	-3	hSpCas9	negative selection	1207799
15651413	15651436	17	-	26627737	RPE1	viability after 15 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-2.19966863249926	[981]	[33,85]	-8	hSpCas9	negative selection	1290112
15651414	15651437	17	-	26627737	RPE1	viability after 15 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-1.7381945883085475	[872]	[128,20]	-8	hSpCas9	negative selection	1290113
15651489	15651512	17	-	26627737	RPE1	viability after 15 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.030461029295824504	[319]	[66,116]	0	hSpCas9	negative selection	1290114
15651413	15651436	17	-	26627737	RPE1	viability after 18 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-3.0544050015857707	[981]	[28,34]	-9	hSpCas9	negative selection	1372427
15651414	15651437	17	-	26627737	RPE1	viability after 18 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-1.013725630864063	[872]	[223,1]	-6	hSpCas9	negative selection	1372428
15651489	15651512	17	-	26627737	RPE1	viability after 18 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.3772911562562091	[319]	[87,137]	2	hSpCas9	negative selection	1372429
15651413	15651436	17	-	26627737	HeLa	viability after 8 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-0.01743946469454083	[102]	[53,36,43]	0	hSpCas9	negative selection	1454742
15651414	15651437	17	-	26627737	HeLa	viability after 8 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-1.0856023724559654	[289]	[84,83,17]	-8	hSpCas9	negative selection	1454743
15651489	15651512	17	-	26627737	HeLa	viability after 8 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.6175024909838747	[353]	[331,175,222]	5	hSpCas9	negative selection	1454744
15651413	15651436	17	-	26627737	HeLa	viability after 12 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-1.6892893499579142	[102]	[16,0,22]	-9	hSpCas9	negative selection	1537057
15651414	15651437	17	-	26627737	HeLa	viability after 12 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-0.6476264239678663	[289]	[95,29,108]	-5	hSpCas9	negative selection	1537058
15651489	15651512	17	-	26627737	HeLa	viability after 12 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-1.0308584293703413	[353]	[127,37,53]	-7	hSpCas9	negative selection	1537059
15651413	15651436	17	-	26627737	HeLa	viability after 15 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-0.8800853755761082	[102]	[15,46,3]	-6	hSpCas9	negative selection	1619372
15651414	15651437	17	-	26627737	HeLa	viability after 15 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	0.12954427761265214	[289]	[188,112,80]	1	hSpCas9	negative selection	1619373
15651489	15651512	17	-	26627737	HeLa	viability after 15 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.23406710030914107	[353]	[93,142,280]	2	hSpCas9	negative selection	1619374
15651413	15651436	17	-	26627737	HeLa	viability after 18 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-0.7938182969166627	[102]	[10,41,3]	-6	hSpCas9	negative selection	1701687
15651414	15651437	17	-	26627737	HeLa	viability after 18 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	0.07651522629547669	[289]	[118,91,80]	0	hSpCas9	negative selection	1701688
15651489	15651512	17	-	26627737	HeLa	viability after 18 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.25923830139692067	[353]	[73,111,280]	2	hSpCas9	negative selection	1701689
15651413	15651436	17	-	26627737	HCT116	viability after 6 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-0.5783517176609014	[194]	[35,11]	-3	hSpCas9	negative selection	1784002
15651414	15651437	17	-	26627737	HCT116	viability after 6 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-0.6803592704141332	[175]	[24,12]	-4	hSpCas9	negative selection	1784003
15651489	15651512	17	-	26627737	HCT116	viability after 6 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.0947497824056428	[920]	[191,133]	0	hSpCas9	negative selection	1784004
15651413	15651436	17	-	26627737	HCT116	viability after 8 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	1.1386575898169191	[31]	[24,33,56]	8	hSpCas9	negative selection	1866317
15651414	15651437	17	-	26627737	HCT116	viability after 8 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	1.4178022578415046	[61]	[74,144,53]	9	hSpCas9	negative selection	1866318
15651489	15651512	17	-	26627737	HCT116	viability after 8 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.20595583461124253	[328]	[99,172,196]	-2	hSpCas9	negative selection	1866319
15651413	15651436	17	-	26627737	HCT116	viability after 9 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	0.45689446490305996	[194]	[128,25]	3	hSpCas9	negative selection	1948632
15651414	15651437	17	-	26627737	HCT116	viability after 9 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	0.27822016688345896	[175]	[37,71]	2	hSpCas9	negative selection	1948633
15651489	15651512	17	-	26627737	HCT116	viability after 9 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.54473015680415	[920]	[224,123]	-4	hSpCas9	negative selection	1948634
15651413	15651436	17	-	26627737	HCT116	viability after 12 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	-0.6130503220658188	[31]	[9,7,14]	-6	hSpCas9	negative selection	2030947
15651414	15651437	17	-	26627737	HCT116	viability after 12 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	1.144091434104304	[61]	[73,77,63]	8	hSpCas9	negative selection	2030948
15651489	15651512	17	-	26627737	HCT116	viability after 12 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.15729289852184292	[328]	[135,204,126]	-2	hSpCas9	negative selection	2030949
15651413	15651436	17	-	26627737	HCT116	viability after 15 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	0.979209452795498	[31]	[48,4,55]	8	hSpCas9	negative selection	2113262
15651414	15651437	17	-	26627737	HCT116	viability after 15 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	1.2754662907159813	[61]	[91,139,27]	8	hSpCas9	negative selection	2113263
15651489	15651512	17	-	26627737	HCT116	viability after 15 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.19945395892931883	[328]	[190,152,152]	-2	hSpCas9	negative selection	2113264
15651413	15651436	17	-	26627737	HCT116	viability after 18 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	1.2147227379248613	[31]	[34,50,19]	8	hSpCas9	negative selection	2195577
15651414	15651437	17	-	26627737	HCT116	viability after 18 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	1.8143560051756495	[61]	[74,102,139]	9	hSpCas9	negative selection	2195578
15651489	15651512	17	-	26627737	HCT116	viability after 18 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.3035166909540201	[328]	[122,170,87]	-3	hSpCas9	negative selection	2195579
15651499	15651522	17	+	24336569	HL60	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	-1.5197884524436562	[228]	[168]	-8	hSpCas9	negative selection	2303411
15651505	15651528	17	-	24336569	HL60	viability	GGTCACCCAGCCCAGATTCTGGG	TRIM16	ENSG00000221926	-1.4475375694012875	[1177]	[913]	-8	hSpCas9	negative selection	2303412
15651516	15651539	17	+	24336569	HL60	viability	GGCTGGGTGACCCAGAGTCTGGG	TRIM16	ENSG00000221926	0.6195626755226926	[377]	[1228]	5	hSpCas9	negative selection	2303413
15651524	15651547	17	+	24336569	HL60	viability	GACCCAGAGTCTGGGCTGAGAGG	TRIM16	ENSG00000221926	0.26298143081989345	[88]	[225]	2	hSpCas9	negative selection	2303414
15651557	15651580	17	+	24336569	HL60	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-1.1965572650608358	[1564]	[1444]	-8	hSpCas9	negative selection	2303415
15651563	15651586	17	+	24336569	HL60	viability	GTGGCCCTGGGCAGTGGCCCTGG	TRIM16	ENSG00000221926	0.004445506980414127	[1311]	[2784]	0	hSpCas9	negative selection	2303416
15651499	15651522	17	+	24336569	KBM7	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	0.676748938453319	[124]	[544]	6	hSpCas9	negative selection	2370588
15651505	15651528	17	-	24336569	KBM7	viability	GGTCACCCAGCCCAGATTCTGGG	TRIM16	ENSG00000221926	0.9173421161067904	[561]	[2894]	7	hSpCas9	negative selection	2370589
15651516	15651539	17	+	24336569	KBM7	viability	GGCTGGGTGACCCAGAGTCTGGG	TRIM16	ENSG00000221926	0.300784724725941	[352]	[1185]	2	hSpCas9	negative selection	2370590
15651524	15651547	17	+	24336569	KBM7	viability	GACCCAGAGTCTGGGCTGAGAGG	TRIM16	ENSG00000221926	0.9370846536864426	[107]	[563]	7	hSpCas9	negative selection	2370591
15651557	15651580	17	+	24336569	KBM7	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-0.5276435854780617	[388]	[735]	-4	hSpCas9	negative selection	2370592
15651563	15651586	17	+	24336569	KBM7	viability	GTGGCCCTGGGCAGTGGCCCTGG	TRIM16	ENSG00000221926	-0.14407819920815879	[1370]	[3383]	-1	hSpCas9	negative selection	2370593
15643042	15643065	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTTGAAATGGTGAGCAGCACGG	TRIM16	ENSG00000221926	-1.9709369064805142	[361,54]	[16,3]	-9	dCas9-VP64	positive selection	2391457
15643078	15643101	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGTATGGCAAGGATGGTGTGGGG	TRIM16	ENSG00000221926	-0.6012335506689204	[394,12]	[19,37]	-3	dCas9-VP64	positive selection	2391458
15643099	15643122	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCTGGTTTACAGCTAGTATGGG	TRIM16	ENSG00000221926	-0.060776344720056	[266,180]	[42,50]	0	dCas9-VP64	positive selection	2391461
15683035	15683058	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACCTGCAAACTCCAGAACAGAGG	TRIM16	ENSG00000221926	0.006306271628196636	[18,80]	[3,18]	0	dCas9-VP64	positive selection	2440100
15682991	15683014	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGATTCTTGGCTAATGGCAGG	TRIM16	ENSG00000221926	-0.5582726022643778	[37,110]	[3,18]	-3	dCas9-VP64	positive selection	2440101
15683024	15683047	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTATTTCTTACCTCTGTTCTGG	TRIM16	ENSG00000221926	-0.9759732672780741	[171,217]	[16,26]	-6	dCas9-VP64	positive selection	2440102
15644299	15644322	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTCCTCGGGAGGCTGAAG	TRIM16	ENSG00000221926	-0.2571104693801929	[13,2]	[1,0]	-1	dCas9-VP64	positive selection	2474823
15672498	15672521	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAAGCAGTCTGCCCACCTTAG	TRIM16	ENSG00000221926	0.20576949065447114	[17,35]	[6,5]	1	dCas9-VP64	positive selection	2476340
15643042	15643065	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTTGAAATGGTGAGCAGCACGG	TRIM16	ENSG00000221926	-0.20968528281410825	[114,409]	[18,123]	-2	dCas9-VP64	positive selection	2486712
15643078	15643101	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGTATGGCAAGGATGGTGTGGGG	TRIM16	ENSG00000221926	-0.861032463084148	[160,92]	[12,30]	-7	dCas9-VP64	positive selection	2486713
15643099	15643122	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCTGGTTTACAGCTAGTATGGG	TRIM16	ENSG00000221926	1.8169110093465495	[511,424]	[896,206]	8	dCas9-VP64	positive selection	2486716
15683035	15683058	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACCTGCAAACTCCAGAACAGAGG	TRIM16	ENSG00000221926	-0.9216575535151602	[178,442]	[42,61]	-8	dCas9-VP64	positive selection	2535355
15682991	15683014	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGATTCTTGGCTAATGGCAGG	TRIM16	ENSG00000221926	-0.019958736518111864	[56,90]	[20,24]	0	dCas9-VP64	positive selection	2535356
15683024	15683047	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTATTTCTTACCTCTGTTCTGG	TRIM16	ENSG00000221926	0.745439220926986	[170,202]	[61,138]	5	dCas9-VP64	positive selection	2535357
15644299	15644322	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTCCTCGGGAGGCTGAAG	TRIM16	ENSG00000221926	0.5230605474514848	[120,26]	[20,47]	4	dCas9-VP64	positive selection	2570078
15672498	15672521	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAAGCAGTCTGCCCACCTTAG	TRIM16	ENSG00000221926	0.6530020702020014	[53,174]	[34,79]	5	dCas9-VP64	positive selection	2571595
15651449	15651472	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTCCCTGCCAAGCTTCTCCGAGG	TRIM16	ENSG00000221926	-0.10459181751415011	[4,4]	[4,2]	-1	hSpCas9	positive selection	3029083
15642781	15642804	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACCCAGTTAGACTTGGAGCGG	TRIM16	ENSG00000221926	-0.11078969557528862	[3,3]	[2,2]	-1	hSpCas9	positive selection	3029084
15636245	15636268	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.2707366972592045	[5,5]	[5,5]	6	hSpCas9	positive selection	3029085
15651489	15651512	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.8101785045962833	[2,3]	[3,5]	9	hSpCas9	positive selection	3029086
15651449	15651472	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTCCCTGCCAAGCTTCTCCGAGG	TRIM16	ENSG00000221926	-0.053043691576532326	[4,4]	[4,1]	0	hSpCas9	positive selection	3096941
15642781	15642804	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACCCAGTTAGACTTGGAGCGG	TRIM16	ENSG00000221926	-0.560601121658995	[3,3]	[1,0]	-7	hSpCas9	positive selection	3096942
15636245	15636268	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.07532242551737706	[5,5]	[5,2]	1	hSpCas9	positive selection	3096943
15651489	15651512	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.8461102268840425	[2,2]	[2,3]	9	hSpCas9	positive selection	3096944
15631662	15631685		-	24336571	A375	resistance to PLX after 7 days	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	-0.05405957750703938	[24,27]	[25,24]	-1	hSpCas9	positive selection	3152548
15636083	15636106		-	24336571	A375	resistance to PLX after 7 days	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.10039994994627088	[1,1]	[1,1]	3	hSpCas9	positive selection	3152549
15636226	15636249		-	24336571	A375	resistance to PLX after 7 days	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.1975118357689924	[9,12]	[13,11]	6	hSpCas9	positive selection	3152550
15631662	15631685		-	24336571	A375	resistance to PLX after 14 days	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	-0.14391274653829944	[26,36]	[12,12]	-1	hSpCas9	positive selection	3210341
15636083	15636106		-	24336571	A375	resistance to PLX after 14 days	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	1.058571280937013	[1,1]	[1,1]	8	hSpCas9	positive selection	3210342
15636226	15636249		-	24336571	A375	resistance to PLX after 14 days	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.019563622226731914	[10,10]	[3,5]	0	hSpCas9	positive selection	3210343
15631662	15631685		-	24336571	A375	viability after 7 days	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.4812475768923641	[19]	[24,27]	7	hSpCas9	negative selection	3268134
15636083	15636106		-	24336571	A375	viability after 7 days	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.07799787107954304	[1]	[1,1]	1	hSpCas9	negative selection	3268135
15636226	15636249		-	24336571	A375	viability after 7 days	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.6551696008274412	[6]	[9,12]	8	hSpCas9	negative selection	3268136
15631662	15631685		-	24336571	A375	viability after 14 days	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.7542817051923769	[19]	[26,36]	8	hSpCas9	negative selection	3325927
15636083	15636106		-	24336571	A375	viability after 14 days	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.0981701428745061	[1]	[1,1]	1	hSpCas9	negative selection	3325928
15636226	15636249		-	24336571	A375	viability after 14 days	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.6346287588532671	[6]	[10,10]	7	hSpCas9	negative selection	3325929
15636226	15636249	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.9174762085612103	[80,80]	[0,0]	4	hSpCas9	positive selection	3398949
15636083	15636106	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.2915419267837481	[124,124]	[0,0]	1	hSpCas9	positive selection	3398950
15642786	15642809	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGTGCACCCAGTTAGACTTGG	TRIM16	ENSG00000221926	-1.032692635486783	[312,312]	[0,0]	-7	hSpCas9	positive selection	3398951
15651448	15651471	17	+	26780180	HT29	viability (Avana library 4 designs)	CTCCCTGCCAAGCTTCTCCGAGG	TRIM16	ENSG00000221926	0.157715535270496	[]	[]	0	hSpCas9	negative selection	3467931
15642781	15642804	17	-	26780180	HT29	viability (Avana library 4 designs)	GCACCCAGTTAGACTTGGAGCGG	TRIM16	ENSG00000221926	1.62908759305588	[]	[]	6	hSpCas9	negative selection	3467932
15636245	15636268	17	-	26780180	HT29	viability (Avana library 4 designs)	GTCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	-0.49342375523865	[]	[]	-7	hSpCas9	negative selection	3467933
15651489	15651512	17	-	26780180	HT29	viability (Avana library 4 designs)	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	1.68962168525993	[]	[]	6	hSpCas9	negative selection	3467934
15642781	15642804	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACCCAGTTAGACTTGGAGCGG	TRIM16	ENSG00000221926	-0.221708047420907	[]	[]	0	hSpCas9	negative selection	3572343
15651489	15651512	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	3.75713109738535	[]	[]	6	hSpCas9	negative selection	3572344
15651448	15651471	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTCCCTGCCAAGCTTCTCCGAGG	TRIM16	ENSG00000221926	3.51785430738105	[]	[]	5	hSpCas9	negative selection	3572345
15636245	15636268	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	6.45483447869929	[]	[]	9	hSpCas9	negative selection	3572346
15651474	15651497	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCACGTCCTCTTCTTCCACTGGG	TRIM16	ENSG00000221926	-0.94400990547684	[]	[]	-1	hSpCas9	negative selection	3572347
15651412	15651435	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	2.87842884062178	[]	[]	4	hSpCas9	negative selection	3572348
15642781	15642804	17	-	26780180	A375	viability (Avana lentiGuide)	GCACCCAGTTAGACTTGGAGCGG	TRIM16	ENSG00000221926	5.41434113969426	[]	[]	5	hSpCas9	negative selection	3681002
15651489	15651512	17	-	26780180	A375	viability (Avana lentiGuide)	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	1.61520931309277	[]	[]	1	hSpCas9	negative selection	3681003
15651448	15651471	17	+	26780180	A375	viability (Avana lentiGuide)	CTCCCTGCCAAGCTTCTCCGAGG	TRIM16	ENSG00000221926	2.27590895150913	[]	[]	2	hSpCas9	negative selection	3681004
15636245	15636268	17	-	26780180	A375	viability (Avana lentiGuide)	GTCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	-3.50131590064095	[]	[]	-6	hSpCas9	negative selection	3681005
15651474	15651497	17	+	26780180	A375	viability (Avana lentiGuide)	CCACGTCCTCTTCTTCCACTGGG	TRIM16	ENSG00000221926	1.32904455560994	[]	[]	1	hSpCas9	negative selection	3681006
15651412	15651435	17	-	26780180	A375	viability (Avana lentiGuide)	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	7.39929964186418	[]	[]	6	hSpCas9	negative selection	3681007
15642781	15642804	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACCCAGTTAGACTTGGAGCGG	TRIM16	ENSG00000221926	-0.624582986751548	[3]	[2,1]	-7	hSpCas9	positive selection	3789609
15651489	15651512	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.10128539443276845	[4]	[4,4]	2	hSpCas9	positive selection	3789610
15651448	15651471	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCCCTGCCAAGCTTCTCCGAGG	TRIM16	ENSG00000221926	0.08035161305763684	[5]	[6,5]	2	hSpCas9	positive selection	3789611
15636245	15636268	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.3380310882841054	[5]	[7,7]	8	hSpCas9	positive selection	3789612
15651474	15651497	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACGTCCTCTTCTTCCACTGGG	TRIM16	ENSG00000221926	-0.13547145846853914	[4]	[4,3]	-2	hSpCas9	positive selection	3789613
15651412	15651435	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	0.13085630067222453	[5]	[6,5]	3	hSpCas9	positive selection	3789614
15642781	15642804	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACCCAGTTAGACTTGGAGCGG	TRIM16	ENSG00000221926	-0.12122334058605602	[5]	[3,5]	-2	hSpCas9	positive selection	3898216
15651489	15651512	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.49006009426880126	[4]	[3,1]	-6	hSpCas9	positive selection	3898217
15651448	15651471	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCCCTGCCAAGCTTCTCCGAGG	TRIM16	ENSG00000221926	0.198529858605086	[6]	[5,6]	5	hSpCas9	positive selection	3898218
15636245	15636268	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.22894670848319387	[6]	[7,6]	6	hSpCas9	positive selection	3898219
15651474	15651497	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACGTCCTCTTCTTCCACTGGG	TRIM16	ENSG00000221926	0.21890920531191427	[6]	[6,5]	5	hSpCas9	positive selection	3898220
15651412	15651435	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	0.03814228971658745	[6]	[5,5]	0	hSpCas9	positive selection	3898221
15632619	15632642	17	-	26780180	A375	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	1.73251597784966	[]	[]	9	hSpCas9	negative selection	4007561
15631662	15631685	17	-	26780180	A375	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	1.02675616663904	[]	[]	5	hSpCas9	negative selection	4007562
15636083	15636106	17	-	26780180	A375	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.732140455251621	[]	[]	2	hSpCas9	negative selection	4007563
15636226	15636249	17	-	26780180	A375	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	1.22318540739729	[]	[]	6	hSpCas9	negative selection	4007564
15632613	15632636	17	+	26780180	A375	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.853666586806489	[]	[]	3	hSpCas9	negative selection	4007565
15632619	15632642	17	-	26780180	HT29	viability (GeCKOv2 library)	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	0.2840257853398	[]	[]	0	hSpCas9	negative selection	4115527
15631662	15631685	17	-	26780180	HT29	viability (GeCKOv2 library)	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.620168107644224	[]	[]	2	hSpCas9	negative selection	4115528
15636083	15636106	17	-	26780180	HT29	viability (GeCKOv2 library)	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	1.92541253442445	[]	[]	9	hSpCas9	negative selection	4115529
15636226	15636249	17	-	26780180	HT29	viability (GeCKOv2 library)	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	1.1128542932812	[]	[]	5	hSpCas9	negative selection	4115530
15632613	15632636	17	+	26780180	HT29	viability (GeCKOv2 library)	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	1.01733455485561	[]	[]	4	hSpCas9	negative selection	4115531
15631662	15631685	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.31274381968755516	[4]	[3,3]	7	hSpCas9	positive selection	4179106
15636083	15636106	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.7310664090553398	[2]	[0,0]	-9	hSpCas9	positive selection	4179107
15636226	15636249	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.05016065624344128	[3]	[2,2]	-1	hSpCas9	positive selection	4179108
15631662	15631685	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	1.2026465974208325	[4]	[7,3,2,3]	8	hSpCas9	positive selection	4243128
15636083	15636106	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.0008554838557032207	[2]	[0,2,0,0]	0	hSpCas9	positive selection	4243129
15636226	15636249	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	1.4958223573794012	[1]	[4,4,2,0]	9	hSpCas9	positive selection	4243130
15632619	15632642	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.03578036383704296	[3]	[3,1]	0	hSpCas9	positive selection	4305038
15632613	15632636	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.05986372278313615	[2]	[2,1]	-1	hSpCas9	positive selection	4305039
15631662	15631685	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.4673181888886574	[3]	[3,3]	8	hSpCas9	positive selection	4305040
15636226	15636249	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.02356286136166219	[1]	[1,0]	0	hSpCas9	positive selection	4369286
15636083	15636106	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.5839449043349584	[2]	[1,0]	-8	hSpCas9	positive selection	4369287
15636245	15636267	17	-	27760321	OCIAML3	viability	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.0714676936343388	[196,175]	[136,173]	0	hSpCas9	negative selection	4449917
15651139	15651161	17	+	27760321	OCIAML3	viability	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	0.5907954503932565	[809,660]	[762,990]	7	hSpCas9	negative selection	4449918
15651159	15651181	17	+	27760321	OCIAML3	viability	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	0.2054464876165656	[701,556]	[449,712]	2	hSpCas9	negative selection	4449919
15651226	15651248	17	-	27760321	OCIAML3	viability	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	0.8279873396977298	[765,621]	[796,1168]	8	hSpCas9	negative selection	4449920
15651305	15651327	17	+	27760321	OCIAML3	viability	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	0.195989598507484	[519,454]	[384,501]	2	hSpCas9	negative selection	4449921
15636245	15636267	17	-	27760321	OCIAML2	viability	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	-0.4105185717099762	[196,175]	[102,126]	-5	hSpCas9	negative selection	4533380
15651139	15651161	17	+	27760321	OCIAML2	viability	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	0.8363145118151966	[809,660]	[785,1413]	9	hSpCas9	negative selection	4533381
15651159	15651181	17	+	27760321	OCIAML2	viability	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	-0.38114608999070254	[701,556]	[363,420]	-4	hSpCas9	negative selection	4533382
15651226	15651248	17	-	27760321	OCIAML2	viability	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	-0.3144107017160538	[765,621]	[389,526]	-4	hSpCas9	negative selection	4533383
15651305	15651327	17	+	27760321	OCIAML2	viability	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	-0.00530416305885667	[519,454]	[382,403]	0	hSpCas9	negative selection	4533384
15636245	15636267	17	-	27760321	MV411	viability	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.4072764415215391	[196,175]	[158,168]	3	hSpCas9	negative selection	4616843
15651139	15651161	17	+	27760321	MV411	viability	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	1.311104815001539	[809,660]	[1517,717]	8	hSpCas9	negative selection	4616844
15651159	15651181	17	+	27760321	MV411	viability	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	1.1178892374562535	[701,556]	[405,1631]	7	hSpCas9	negative selection	4616845
15651226	15651248	17	-	27760321	MV411	viability	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	0.0214774307539769	[765,621]	[230,809]	0	hSpCas9	negative selection	4616846
15651305	15651327	17	+	27760321	MV411	viability	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	-0.3946917739384014	[519,454]	[204,302]	-3	hSpCas9	negative selection	4616847
15636245	15636267	17	-	27760321	HL60	viability	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	-0.11940598923137058	[196,175]	[141,137]	-1	hSpCas9	negative selection	4700306
15651139	15651161	17	+	27760321	HL60	viability	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	0.8259642173004845	[809,660]	[983,1139]	8	hSpCas9	negative selection	4700307
15651159	15651181	17	+	27760321	HL60	viability	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	-0.19284307755211327	[701,556]	[400,495]	-2	hSpCas9	negative selection	4700308
15651226	15651248	17	-	27760321	HL60	viability	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	1.49001768061548	[765,621]	[1503,1668]	9	hSpCas9	negative selection	4700309
15651305	15651327	17	+	27760321	HL60	viability	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	0.2856585976982492	[519,454]	[396,576]	3	hSpCas9	negative selection	4700310
15636245	15636267	17	-	27760321	HT1080	viability	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.6503104459245149	[175,137]	[38,162]	3	hSpCas9	negative selection	4783769
15651139	15651161	17	+	27760321	HT1080	viability	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	0.403169125322951	[660,515]	[257,366]	2	hSpCas9	negative selection	4783770
15651159	15651181	17	+	27760321	HT1080	viability	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	0.8869947455250613	[556,434]	[268,470]	5	hSpCas9	negative selection	4783771
15651226	15651248	17	-	27760321	HT1080	viability	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	-1.2174414189187295	[621,485]	[50,142]	-5	hSpCas9	negative selection	4783772
15651305	15651327	17	+	27760321	HT1080	viability	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	0.32907320091714165	[454,354]	[258,140]	1	hSpCas9	negative selection	4783773
15636245	15636267	17	-	27760321	HT29	viability after 7 days	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.07967640333893278	[175,137]	[222,261,157]	1	hSpCas9	negative selection	4867232
15651139	15651161	17	+	27760321	HT29	viability after 7 days	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	0.38139842116821443	[660,515]	[1017,827,1109]	6	hSpCas9	negative selection	4867233
15651159	15651181	17	+	27760321	HT29	viability after 7 days	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	0.1308361583764624	[556,434]	[894,786,447]	2	hSpCas9	negative selection	4867234
15651226	15651248	17	-	27760321	HT29	viability after 7 days	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	0.48679638168909856	[621,485]	[1142,972,900]	7	hSpCas9	negative selection	4867235
15651305	15651327	17	+	27760321	HT29	viability after 7 days	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	-0.566751297786094	[454,354]	[420,226,413]	-7	hSpCas9	negative selection	4867236
15636245	15636267	17	-	27760321	HT29	viability after 25 days	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.28126425943108346	[175,137]	[164,190,310]	3	hSpCas9	negative selection	4950695
15651139	15651161	17	+	27760321	HT29	viability after 25 days	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	0.5365731738493633	[660,515]	[963,916,1052]	6	hSpCas9	negative selection	4950696
15651159	15651181	17	+	27760321	HT29	viability after 25 days	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	0.37360108923870233	[556,434]	[776,579,854]	4	hSpCas9	negative selection	4950697
15651226	15651248	17	-	27760321	HT29	viability after 25 days	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	0.9524459712957418	[621,485]	[915,1176,1643]	9	hSpCas9	negative selection	4950698
15651305	15651327	17	+	27760321	HT29	viability after 25 days	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	0.2526294642517536	[454,354]	[592,581,466]	2	hSpCas9	negative selection	4950699
15636245	15636267	17	-	27760321	HT29	viability after 22 days	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.37056736027197223	[175,137]	[195,190,318]	4	hSpCas9	negative selection	5034158
15651139	15651161	17	+	27760321	HT29	viability after 22 days	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	0.7521834617810728	[660,515]	[854,985,1608]	8	hSpCas9	negative selection	5034159
15651159	15651181	17	+	27760321	HT29	viability after 22 days	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	0.12244491068649105	[556,434]	[662,539,668]	1	hSpCas9	negative selection	5034160
15651226	15651248	17	-	27760321	HT29	viability after 22 days	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	1.0919137322047112	[621,485]	[1545,1162,1381]	9	hSpCas9	negative selection	5034161
15651305	15651327	17	+	27760321	HT29	viability after 22 days	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	0.2759881953427623	[454,354]	[777,345,570]	3	hSpCas9	negative selection	5034162
15636245	15636267	17	-	27760321	HT29	viability after 19 days	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.4029759649888246	[175,137]	[231,222,255]	4	hSpCas9	negative selection	5117621
15651139	15651161	17	+	27760321	HT29	viability after 19 days	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	0.6826888738117312	[660,515]	[975,813,1425]	7	hSpCas9	negative selection	5117622
15651159	15651181	17	+	27760321	HT29	viability after 19 days	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	0.17655174546196145	[556,434]	[845,606,496]	1	hSpCas9	negative selection	5117623
15651226	15651248	17	-	27760321	HT29	viability after 19 days	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	0.7128105257345421	[621,485]	[1067,1279,779]	7	hSpCas9	negative selection	5117624
15651305	15651327	17	+	27760321	HT29	viability after 19 days	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	-0.40841295392413157	[454,354]	[294,314,427]	-4	hSpCas9	negative selection	5117625
15636245	15636267	17	-	27760321	HT29	viability after 16 days	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.19893141080924648	[175,137]	[210,273,118]	2	hSpCas9	negative selection	5201084
15651139	15651161	17	+	27760321	HT29	viability after 16 days	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	0.9286217404425852	[660,515]	[1057,992,1696]	9	hSpCas9	negative selection	5201085
15651159	15651181	17	+	27760321	HT29	viability after 16 days	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	-0.030654702233563147	[556,434]	[842,277,543]	0	hSpCas9	negative selection	5201086
15651226	15651248	17	-	27760321	HT29	viability after 16 days	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	1.0867751507092869	[621,485]	[1228,1440,1267]	9	hSpCas9	negative selection	5201087
15651305	15651327	17	+	27760321	HT29	viability after 16 days	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	-0.036924132505326196	[454,354]	[494,515,316]	0	hSpCas9	negative selection	5201088
15636245	15636267	17	-	27760321	HT29	viability after 13 days	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	-0.05653922614316298	[175,137]	[166,156,199]	0	hSpCas9	negative selection	5284547
15651139	15651161	17	+	27760321	HT29	viability after 13 days	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	0.5914631302116065	[660,515]	[991,910,1173]	7	hSpCas9	negative selection	5284548
15651159	15651181	17	+	27760321	HT29	viability after 13 days	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	0.31257990888102044	[556,434]	[825,780,546]	4	hSpCas9	negative selection	5284549
15651226	15651248	17	-	27760321	HT29	viability after 13 days	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	0.6893268011155322	[621,485]	[1021,1115,974]	8	hSpCas9	negative selection	5284550
15651305	15651327	17	+	27760321	HT29	viability after 13 days	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	-0.14472979317581952	[454,354]	[508,311,451]	-2	hSpCas9	negative selection	5284551
15636245	15636267	17	-	27760321	HT29	viability after 10 days	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	0.12460437086939624	[175,137]	[234,238,168]	1	hSpCas9	negative selection	5368010
15651139	15651161	17	+	27760321	HT29	viability after 10 days	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	0.16306576985542287	[660,515]	[1034,847,590]	2	hSpCas9	negative selection	5368011
15651159	15651181	17	+	27760321	HT29	viability after 10 days	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	0.17998041622269317	[556,434]	[837,546,714]	2	hSpCas9	negative selection	5368012
15651226	15651248	17	-	27760321	HT29	viability after 10 days	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	0.7590325972088414	[621,485]	[829,1345,1336]	9	hSpCas9	negative selection	5368013
15651305	15651327	17	+	27760321	HT29	viability after 10 days	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	-0.37907501428672774	[454,354]	[451,352,360]	-5	hSpCas9	negative selection	5368014
15636245	15636267	17	-	27760321	MOLM13	viability	TCGGTGTCAGAGGTCAAAGCGG	TRIM16	ENSG00000221926	-0.23599107564897093	[196,175]	[139,45]	-1	hSpCas9	negative selection	5451473
15651139	15651161	17	+	27760321	MOLM13	viability	GTGCTCCTGGCAACAGTCCTGG	TRIM16	ENSG00000221926	-0.3303938420382441	[809,660]	[430,240]	-2	hSpCas9	negative selection	5451474
15651159	15651181	17	+	27760321	MOLM13	viability	GGCAGATGCACTGCTGATCAGG	TRIM16	ENSG00000221926	0.2445707025067969	[701,556]	[361,465]	1	hSpCas9	negative selection	5451475
15651226	15651248	17	-	27760321	MOLM13	viability	GCCAGTGAAGGACCACAACTGG	TRIM16	ENSG00000221926	0.7588267008609837	[765,621]	[314,951]	5	hSpCas9	negative selection	5451476
15651305	15651327	17	+	27760321	MOLM13	viability	TCACAGTAATTCACCATGCAGG	TRIM16	ENSG00000221926	0.4090072998218366	[519,454]	[237,471]	3	hSpCas9	negative selection	5451477
15683943	15683966	17	-	27661255	K562	viability	GGCTGAGGGCCCGCATACCCTGG	TRIM16	ENSG00000221926	0.13818132495506108	[408,446]	[447,313]	5	dCas9-KRAB	negative selection	5519623
15684223	15684246	17	-	27661255	K562	viability	GCAGACACCCTCTCTGTGTCTGG	TRIM16	ENSG00000221926	0.2634403392812341	[1134,1270]	[1250,1065]	8	dCas9-KRAB	negative selection	5519624
15642888	15642911	17	-	27661255	K562	viability	GAAGAAGGGCGGGGATGTCAGGG	TRIM16	ENSG00000221926	-0.17426876236081706	[1083,1082]	[786,749]	-5	dCas9-KRAB	negative selection	5519627
15642939	15642962	17	+	27661255	K562	viability	GATCTCAGAAACCAGCCGGGAGG	TRIM16	ENSG00000221926	0.09189284236830297	[284,293]	[241,249]	3	dCas9-KRAB	negative selection	5519630
15632619	15632642	17	-	27260156	BXPC3	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	0.033752543226096055	[591]	[637,596,615,686]	0	hSpCas9	negative selection	5577498
15632613	15632636	17	+	27260156	BXPC3	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.12354568117473552	[337]	[237,377,305,386]	-3	hSpCas9	negative selection	5577499
15631662	15631685	17	-	27260156	BXPC3	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.1486027100598864	[623]	[635,672,688,926]	3	hSpCas9	negative selection	5577500
15636226	15636249	17	-	27260156	BXPC3	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.10619808624307714	[176]	[168,191,137,187]	-2	hSpCas9	negative selection	5641746
15636083	15636106	17	-	27260156	BXPC3	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.16160772371831178	[284]	[243,310,233,274]	-4	hSpCas9	negative selection	5641747
15632619	15632642	17	-	27260156	A673	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.09115584344517164	[591]	[678,669,671,646]	-2	hSpCas9	negative selection	5698749
15632613	15632636	17	+	27260156	A673	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.012388151925980528	[337]	[519,430,374,317]	0	hSpCas9	negative selection	5698750
15631662	15631685	17	-	27260156	A673	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.3858310905693652	[623]	[993,1026,900,993]	8	hSpCas9	negative selection	5698751
15636226	15636249	17	-	27260156	A673	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.23255932788733413	[176]	[281,199,258,262]	5	hSpCas9	negative selection	5762997
15636083	15636106	17	-	27260156	A673	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.29982535311155945	[284]	[323,263,226,303]	-6	hSpCas9	negative selection	5762998
15632619	15632642	17	-	27260156	A375	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.6028685357453747	[591]	[458,630,401,362]	-7	hSpCas9	negative selection	5820000
15632613	15632636	17	+	27260156	A375	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.12486606132882672	[337]	[468,446,297,257]	-2	hSpCas9	negative selection	5820001
15631662	15631685	17	-	27260156	A375	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.3226880436552609	[623]	[804,1134,887,851]	5	hSpCas9	negative selection	5820002
15636226	15636249	17	-	27260156	A375	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.521596450755929	[176]	[155,315,320,383]	7	hSpCas9	negative selection	5884248
15636083	15636106	17	-	27260156	A375	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.4365783471038026	[284]	[202,258,272,248]	-6	hSpCas9	negative selection	5884249
15632619	15632642	17	-	27260156	COLO741	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	0.12103172479955993	[591]	[780,1032,660]	2	hSpCas9	negative selection	5941251
15632613	15632636	17	+	27260156	COLO741	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.0791927285894638	[337]	[385,336,493]	-2	hSpCas9	negative selection	5941252
15631662	15631685	17	-	27260156	COLO741	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.23674996921725328	[623]	[981,1053,794]	5	hSpCas9	negative selection	5941253
15636226	15636249	17	-	27260156	COLO741	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.05018726131608098	[176]	[213,271,171]	-1	hSpCas9	negative selection	6005499
15636083	15636106	17	-	27260156	COLO741	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.24450508204507715	[284]	[270,333,312]	-5	hSpCas9	negative selection	6005500
15632619	15632642	17	-	27260156	CAL120	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.493639688001118	[591]	[564,559,451]	-6	hSpCas9	negative selection	6062502
15632613	15632636	17	+	27260156	CAL120	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.35326656112343013	[337]	[472,304,232]	-5	hSpCas9	negative selection	6062503
15631662	15631685	17	-	27260156	CAL120	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.32507225078705276	[623]	[857,1038,1002]	5	hSpCas9	negative selection	6062504
15636226	15636249	17	-	27260156	CAL120	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.3222369658039783	[176]	[276,202,344]	5	hSpCas9	negative selection	6126750
15636083	15636106	17	-	27260156	CAL120	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.19385726884575594	[284]	[317,389,493]	3	hSpCas9	negative selection	6126751
15632619	15632642	17	-	27260156	CADOES1	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.35420668859687343	[591]	[451,367,464,437]	-6	hSpCas9	negative selection	6183753
15632613	15632636	17	+	27260156	CADOES1	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.01838163998641046	[337]	[506,196,271,295]	0	hSpCas9	negative selection	6183754
15631662	15631685	17	-	27260156	CADOES1	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.47721048798200644	[623]	[836,918,558,920]	7	hSpCas9	negative selection	6183755
15636226	15636249	17	-	27260156	CADOES1	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.5483628764811247	[176]	[220,325,282,128]	8	hSpCas9	negative selection	6248001
15636083	15636106	17	-	27260156	CADOES1	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.1732857599143406	[284]	[316,282,232,364]	3	hSpCas9	negative selection	6248002
15632619	15632642	17	-	27260156	EWS502	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	0.07165340001286175	[591]	[563,832,654,579]	1	hSpCas9	negative selection	6305004
15632613	15632636	17	+	27260156	EWS502	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.015101449318813354	[337]	[402,412,293,324]	0	hSpCas9	negative selection	6305005
15631662	15631685	17	-	27260156	EWS502	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.5196247832169489	[623]	[952,787,837,1231]	8	hSpCas9	negative selection	6305006
15636226	15636249	17	-	27260156	EWS502	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.11952868513650605	[176]	[132,133,227,203]	-2	hSpCas9	negative selection	6369252
15636083	15636106	17	-	27260156	EWS502	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.039560107379067455	[284]	[128,344,431,286]	0	hSpCas9	negative selection	6369253
15632619	15632642	17	-	27260156	EW8	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.35477860223399355	[591]	[468,282,353,406]	-6	hSpCas9	negative selection	6426255
15632613	15632636	17	+	27260156	EW8	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.20899221007095742	[337]	[233,295,352,366]	4	hSpCas9	negative selection	6426256
15631662	15631685	17	-	27260156	EW8	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.2338056519342811	[623]	[658,640,537,555]	4	hSpCas9	negative selection	6426257
15636226	15636249	17	-	27260156	EW8	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.39853194207912956	[176]	[112,120,75,130]	-6	hSpCas9	negative selection	6490503
15636083	15636106	17	-	27260156	EW8	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.19989520475658273	[284]	[216,308,188,352]	3	hSpCas9	negative selection	6490504
15632619	15632642	17	-	27260156	CORL105	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.47821128717403827	[591]	[572,407,558,463]	-7	hSpCas9	negative selection	6547506
15632613	15632636	17	+	27260156	CORL105	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.39606585481404855	[337]	[376,226,220,368]	-6	hSpCas9	negative selection	6547507
15631662	15631685	17	-	27260156	CORL105	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.4083746196841997	[623]	[1023,975,914,955]	7	hSpCas9	negative selection	6547508
15636226	15636249	17	-	27260156	CORL105	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.027831966486681514	[176]	[226,161,246,215]	0	hSpCas9	negative selection	6611754
15636083	15636106	17	-	27260156	CORL105	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.2907254901606996	[284]	[192,251,277,365]	-5	hSpCas9	negative selection	6611755
15632619	15632642	17	-	27260156	HS294T	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.6746600646080982	[591]	[155,113,123,185]	-7	hSpCas9	negative selection	6668757
15632613	15632636	17	+	27260156	HS294T	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.1930528206565576	[337]	[88,74,185,109]	-3	hSpCas9	negative selection	6668758
15631662	15631685	17	-	27260156	HS294T	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	1.1963023455503135	[623]	[409,922,403,457]	9	hSpCas9	negative selection	6668759
15636226	15636249	17	-	27260156	HS294T	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.2825781199641646	[176]	[37,123,58,120]	4	hSpCas9	negative selection	6733005
15636083	15636106	17	-	27260156	HS294T	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.1467794189671412	[284]	[145,36,123,192]	2	hSpCas9	negative selection	6733006
15632619	15632642	17	-	27260156	HCC44	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.3280835890658057	[591]	[403,484,795,485]	-5	hSpCas9	negative selection	6790008
15632613	15632636	17	+	27260156	HCC44	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.3257435387015658	[337]	[582,296,772,349]	5	hSpCas9	negative selection	6790009
15631662	15631685	17	-	27260156	HCC44	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.39616899393885147	[623]	[909,595,1492,853]	6	hSpCas9	negative selection	6790010
15636226	15636249	17	-	27260156	HCC44	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.15513027922791411	[176]	[93,228,309,257]	2	hSpCas9	negative selection	6854256
15636083	15636106	17	-	27260156	HCC44	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.08542141990254959	[284]	[251,264,390,319]	-1	hSpCas9	negative selection	6854257
15632619	15632642	17	-	27260156	G402	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.5306991333846652	[591]	[458,501,353,668]	-6	hSpCas9	negative selection	6911259
15632613	15632636	17	+	27260156	G402	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.11496146094482695	[337]	[320,300,218,894]	1	hSpCas9	negative selection	6911260
15631662	15631685	17	-	27260156	G402	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.2966240403673844	[623]	[894,777,1150,899]	4	hSpCas9	negative selection	6911261
15636226	15636249	17	-	27260156	G402	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.5881244598293414	[176]	[322,399,262,315]	7	hSpCas9	negative selection	6975507
15636083	15636106	17	-	27260156	G402	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.03236913508396222	[284]	[270,106,585,426]	0	hSpCas9	negative selection	6975508
15632619	15632642	17	-	27260156	L33	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.12870433834173306	[591]	[601,236,323,468]	-3	hSpCas9	negative selection	7032510
15632613	15632636	17	+	27260156	L33	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.04444990884853578	[337]	[410,106,246,327]	1	hSpCas9	negative selection	7032511
15631662	15631685	17	-	27260156	L33	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.32540914294086926	[623]	[819,336,484,712]	7	hSpCas9	negative selection	7032512
15636226	15636249	17	-	27260156	L33	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.11232775995632993	[176]	[190,82,96,216]	2	hSpCas9	negative selection	7096758
15636083	15636106	17	-	27260156	L33	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.007550453392913159	[284]	[186,128,201,324]	0	hSpCas9	negative selection	7096759
15632619	15632642	17	-	27260156	K562	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.3217800887793534	[591]	[309,351,660,351]	-4	hSpCas9	negative selection	7153761
15632613	15632636	17	+	27260156	K562	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.2734864895662007	[337]	[317,243,308,138]	-3	hSpCas9	negative selection	7153762
15631662	15631685	17	-	27260156	K562	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.6474373443034058	[623]	[1021,834,574,1025]	8	hSpCas9	negative selection	7153763
15636226	15636249	17	-	27260156	K562	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.33702597293221936	[176]	[90,181,168,325]	4	hSpCas9	negative selection	7218009
15636083	15636106	17	-	27260156	K562	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.056721978924377026	[284]	[289,482,180,126]	0	hSpCas9	negative selection	7218010
15632619	15632642	17	-	27260156	HT29	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.14328536674435377	[591]	[909,794,574,386]	-3	hSpCas9	negative selection	7275012
15632613	15632636	17	+	27260156	HT29	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.2630843790651286	[337]	[369,324,404,275]	-5	hSpCas9	negative selection	7275013
15631662	15631685	17	-	27260156	HT29	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.44635356058931813	[623]	[893,1168,1329,767]	8	hSpCas9	negative selection	7275014
15636226	15636249	17	-	27260156	HT29	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.2737627626478545	[176]	[188,198,162,163]	-5	hSpCas9	negative selection	7339260
15636083	15636106	17	-	27260156	HT29	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.18369314526424452	[284]	[432,263,327,210]	-4	hSpCas9	negative selection	7339261
15632619	15632642	17	-	27260156	MHHES1	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.44484188198349145	[591]	[513,626,465,382]	-7	hSpCas9	negative selection	7396263
15632613	15632636	17	+	27260156	MHHES1	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.002635401988067665	[337]	[340,442,259,450]	0	hSpCas9	negative selection	7396264
15631662	15631685	17	-	27260156	MHHES1	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.47611345360938245	[623]	[926,1015,1140,835]	8	hSpCas9	negative selection	7396265
15636226	15636249	17	-	27260156	MHHES1	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.05252266736703781	[176]	[145,219,290,121]	-1	hSpCas9	negative selection	7460511
15636083	15636106	17	-	27260156	MHHES1	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.3151646505583744	[284]	[289,315,210,225]	-5	hSpCas9	negative selection	7460512
15632619	15632642	17	-	27260156	MEWO	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	0.08766222729891415	[591]	[548,558,649]	2	hSpCas9	negative selection	7517514
15632613	15632636	17	+	27260156	MEWO	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.1277146890273086	[337]	[476,318,265]	3	hSpCas9	negative selection	7517515
15631662	15631685	17	-	27260156	MEWO	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.11364471815645488	[623]	[719,608,582]	2	hSpCas9	negative selection	7517516
15636226	15636249	17	-	27260156	MEWO	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.4485030082902224	[176]	[166,92,112]	-7	hSpCas9	negative selection	7581762
15636083	15636106	17	-	27260156	MEWO	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.511929597512606	[284]	[228,198,140]	-8	hSpCas9	negative selection	7581763
15632619	15632642	17	-	27260156	LNCAPCLONEFGC	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.6807546910830728	[591]	[393,295,338,310]	-7	hSpCas9	negative selection	7638765
15632613	15632636	17	+	27260156	LNCAPCLONEFGC	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.2274449863879423	[337]	[282,147,274,348]	-4	hSpCas9	negative selection	7638766
15631662	15631685	17	-	27260156	LNCAPCLONEFGC	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.4329715675524552	[623]	[744,824,741,732]	6	hSpCas9	negative selection	7638767
15636226	15636249	17	-	27260156	LNCAPCLONEFGC	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.2964180056758423	[176]	[287,146,189,162]	5	hSpCas9	negative selection	7703013
15636083	15636106	17	-	27260156	LNCAPCLONEFGC	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.06642202366453387	[284]	[237,276,251,217]	-1	hSpCas9	negative selection	7703014
15632619	15632642	17	-	27260156	PANC0327	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.1925322152544234	[591]	[638,342,294,592]	-3	hSpCas9	negative selection	7760016
15632613	15632636	17	+	27260156	PANC0327	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.03060536760190191	[337]	[263,353,284,313]	0	hSpCas9	negative selection	7760017
15631662	15631685	17	-	27260156	PANC0327	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.5526483627738707	[623]	[809,773,950,721]	7	hSpCas9	negative selection	7760018
15636226	15636249	17	-	27260156	PANC0327	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.012497838932023608	[176]	[262,55,105,219]	0	hSpCas9	negative selection	7824264
15636083	15636106	17	-	27260156	PANC0327	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.17445189930548977	[284]	[270,262,157,203]	-3	hSpCas9	negative selection	7824265
15632619	15632642	17	-	27260156	NCIH2009	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.4964334837867598	[591]	[669,501,603]	-6	hSpCas9	negative selection	7881267
15632613	15632636	17	+	27260156	NCIH2009	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.25091950702235233	[337]	[556,501,625]	3	hSpCas9	negative selection	7881268
15631662	15631685	17	-	27260156	NCIH2009	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.5446977150021401	[623]	[1453,1111,1285]	7	hSpCas9	negative selection	7881269
15636226	15636249	17	-	27260156	NCIH2009	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.9041139728366313	[176]	[593,270,551]	9	hSpCas9	negative selection	7945515
15636083	15636106	17	-	27260156	NCIH2009	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.027852975046338213	[284]	[487,242,461]	0	hSpCas9	negative selection	7945516
15632619	15632642	17	-	27260156	NCIH1373	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.6384477818765837	[591]	[699,166,349,148]	-6	hSpCas9	negative selection	8002518
15632613	15632636	17	+	27260156	NCIH1373	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.15765769976981647	[337]	[409,248,406,80]	-1	hSpCas9	negative selection	8002519
15631662	15631685	17	-	27260156	NCIH1373	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.9023784226454605	[623]	[1751,1244,1313,253]	8	hSpCas9	negative selection	8002520
15636226	15636249	17	-	27260156	NCIH1373	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.038905115856505024	[176]	[352,165,83,63]	0	hSpCas9	negative selection	8066766
15636083	15636106	17	-	27260156	NCIH1373	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	0.26211795288305356	[284]	[447,305,332,122]	2	hSpCas9	negative selection	8066767
15632619	15632642	17	-	27260156	PATU8902	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.5324925178740869	[591]	[301,571,954,319]	-5	hSpCas9	negative selection	8123769
15632613	15632636	17	+	27260156	PATU8902	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.5389701382497759	[337]	[593,315,101,336]	-5	hSpCas9	negative selection	8123770
15631662	15631685	17	-	27260156	PATU8902	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	1.048831770403337	[623]	[1467,1877,1144,3004]	9	hSpCas9	negative selection	8123771
15636226	15636249	17	-	27260156	PATU8902	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.08370556429708254	[176]	[151,417,97,305]	-1	hSpCas9	negative selection	8188017
15636083	15636106	17	-	27260156	PATU8902	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.32921832285074515	[284]	[269,207,329,467]	-3	hSpCas9	negative selection	8188018
15632619	15632642	17	-	27260156	PANC1	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.21020690990326954	[591]	[498,662,427,238]	-3	hSpCas9	negative selection	8245020
15632613	15632636	17	+	27260156	PANC1	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.07051639041009028	[337]	[360,352,223,190]	-1	hSpCas9	negative selection	8245021
15631662	15631685	17	-	27260156	PANC1	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.37444894352893415	[623]	[727,662,647,716]	6	hSpCas9	negative selection	8245022
15636226	15636249	17	-	27260156	PANC1	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.13537567528953143	[176]	[81,167,244,171]	2	hSpCas9	negative selection	8309268
15636083	15636106	17	-	27260156	PANC1	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.5617255868399252	[284]	[188,188,196,100]	-7	hSpCas9	negative selection	8309269
15632619	15632642	17	-	27260156	PANC0813	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.2953986597239207	[591]	[579,484,751,456]	-5	hSpCas9	negative selection	8366271
15632613	15632636	17	+	27260156	PANC0813	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.022975471730317776	[337]	[403,389,420,350]	0	hSpCas9	negative selection	8366272
15631662	15631685	17	-	27260156	PANC0813	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.7768807743787811	[623]	[1181,1298,1144,1380]	9	hSpCas9	negative selection	8366273
15636226	15636249	17	-	27260156	PANC0813	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.10222778615777739	[176]	[237,163,234,254]	1	hSpCas9	negative selection	8430519
15636083	15636106	17	-	27260156	PANC0813	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.16119400404685202	[284]	[176,425,204,372]	-3	hSpCas9	negative selection	8430520
15632619	15632642	17	-	27260156	RDES	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.29396824071093475	[591]	[493,552,586,588]	-5	hSpCas9	negative selection	8487522
15632613	15632636	17	+	27260156	RDES	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.17928926840498693	[337]	[328,220,347,503]	-3	hSpCas9	negative selection	8487523
15631662	15631685	17	-	27260156	RDES	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.4082278648927609	[623]	[793,886,1112,1046]	6	hSpCas9	negative selection	8487524
15636226	15636249	17	-	27260156	RDES	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.10105938628867173	[176]	[176,185,292,226]	1	hSpCas9	negative selection	8551770
15636083	15636106	17	-	27260156	RDES	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.35639027183654337	[284]	[257,248,216,295]	-6	hSpCas9	negative selection	8551771
15632619	15632642	17	-	27260156	PC3	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.013681580431599116	[591]	[283,434,1031,869]	0	hSpCas9	negative selection	8608773
15632613	15632636	17	+	27260156	PC3	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.3078770479310732	[337]	[189,194,541,278]	-6	hSpCas9	negative selection	8608774
15631662	15631685	17	-	27260156	PC3	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.11602461839377304	[623]	[442,734,904,733]	2	hSpCas9	negative selection	8608775
15636226	15636249	17	-	27260156	PC3	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.142451642103534	[176]	[130,188,369,163]	3	hSpCas9	negative selection	8673021
15636083	15636106	17	-	27260156	PC3	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.06173272890926629	[284]	[179,176,443,377]	-1	hSpCas9	negative selection	8673022
15632619	15632642	17	-	27260156	PATU8988T	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.48362149147119804	[591]	[487,372,281,498]	-7	hSpCas9	negative selection	8730024
15632613	15632636	17	+	27260156	PATU8988T	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.14986973901663708	[337]	[348,391,410,293]	2	hSpCas9	negative selection	8730025
15631662	15631685	17	-	27260156	PATU8988T	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.20206538559425719	[623]	[747,643,633,748]	3	hSpCas9	negative selection	8730026
15636226	15636249	17	-	27260156	PATU8988T	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.4771433959789737	[176]	[269,303,173,208]	7	hSpCas9	negative selection	8794272
15636083	15636106	17	-	27260156	PATU8988T	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.4142574791308308	[284]	[131,129,313,244]	-6	hSpCas9	negative selection	8794273
15632619	15632642	17	-	27260156	T47D	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	0.015617675275677645	[591]	[722,687,612,768]	0	hSpCas9	negative selection	8851275
15632613	15632636	17	+	27260156	T47D	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.14196850478679252	[337]	[456,393,375,517]	3	hSpCas9	negative selection	8851276
15631662	15631685	17	-	27260156	T47D	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.36553308637608256	[623]	[943,841,923,1047]	7	hSpCas9	negative selection	8851277
15636226	15636249	17	-	27260156	T47D	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.014209505958070245	[176]	[240,155,153,272]	0	hSpCas9	negative selection	8915523
15636083	15636106	17	-	27260156	T47D	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.007582764177798462	[284]	[306,344,367,297]	0	hSpCas9	negative selection	8915524
15632619	15632642	17	-	27260156	SU8686	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	0.05331601462844143	[591]	[525,555,525,881]	0	hSpCas9	negative selection	8972526
15632613	15632636	17	+	27260156	SU8686	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.15986430400470858	[337]	[333,317,412,455]	2	hSpCas9	negative selection	8972527
15631662	15631685	17	-	27260156	SU8686	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.6796184992416083	[623]	[1037,792,924,1262]	9	hSpCas9	negative selection	8972528
15636226	15636249	17	-	27260156	SU8686	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.02951408322028448	[176]	[172,198,109,238]	0	hSpCas9	negative selection	9036774
15636083	15636106	17	-	27260156	SU8686	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.19125512147942025	[284]	[260,210,352,153]	-3	hSpCas9	negative selection	9036775
15632619	15632642	17	-	27260156	SKES1	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.12748539076647022	[591]	[499,671,507,492]	-3	hSpCas9	negative selection	9093777
15632613	15632636	17	+	27260156	SKES1	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.06358138482827769	[337]	[392,250,391,258]	-1	hSpCas9	negative selection	9093778
15631662	15631685	17	-	27260156	SKES1	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.26031431427082913	[623]	[820,907,676,614]	5	hSpCas9	negative selection	9093779
15636226	15636249	17	-	27260156	SKES1	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	-0.1546016286481544	[176]	[195,132,94,205]	-3	hSpCas9	negative selection	9158025
15636083	15636106	17	-	27260156	SKES1	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.5630692432443695	[284]	[274,197,137,171]	-8	hSpCas9	negative selection	9158026
15632619	15632642	17	-	27260156	TOV112D	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	0.04379179749340889	[591]	[690,605,388,758]	0	hSpCas9	negative selection	9215028
15632613	15632636	17	+	27260156	TOV112D	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.25004747190702786	[337]	[475,435,414,299]	5	hSpCas9	negative selection	9215029
15631662	15631685	17	-	27260156	TOV112D	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.4275770865875634	[623]	[699,1116,539,1053]	7	hSpCas9	negative selection	9215030
15636226	15636249	17	-	27260156	TOV112D	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.08011915124907976	[176]	[118,233,214,186]	1	hSpCas9	negative selection	9279276
15636083	15636106	17	-	27260156	TOV112D	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.24274360659333982	[284]	[301,462,117,143]	-5	hSpCas9	negative selection	9279277
15632619	15632642	17	-	27260156	TC71	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.012833077604252896	[591]	[522,701,623,671]	0	hSpCas9	negative selection	9336279
15632613	15632636	17	+	27260156	TC71	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	-0.2140654289454027	[337]	[349,310,382,194]	-5	hSpCas9	negative selection	9336280
15631662	15631685	17	-	27260156	TC71	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.30502923017960676	[623]	[764,933,814,790]	7	hSpCas9	negative selection	9336281
15636226	15636249	17	-	27260156	TC71	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.04920537979909456	[176]	[143,219,199,223]	1	hSpCas9	negative selection	9400527
15636083	15636106	17	-	27260156	TC71	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.167665905614093	[284]	[247,336,249,252]	-4	hSpCas9	negative selection	9400528
15632619	15632642	17	-	27260156	TC32	viability	ACCTTCCCTAGTGTTTACGTAGG	TRIM16	ENSG00000221926	-0.31527533837918637	[591]	[438,385,597,383]	-5	hSpCas9	negative selection	9457530
15632613	15632636	17	+	27260156	TC32	viability	TTCAGCCCTACGTAAACACTAGG	TRIM16	ENSG00000221926	0.31065452677426186	[337]	[344,376,479,374]	5	hSpCas9	negative selection	9457531
15631662	15631685	17	-	27260156	TC32	viability	CCGTTGTTCAGCGCAAATATTGG	TRIM16	ENSG00000221926	0.5263091301422116	[623]	[795,674,1036,926]	8	hSpCas9	negative selection	9457532
15636226	15636249	17	-	27260156	TC32	viability	GCGGTGGCTGAAATGCAGTTTGG	TRIM16	ENSG00000221926	0.25931898033893397	[176]	[159,198,307,136]	4	hSpCas9	negative selection	9521778
15636083	15636106	17	-	27260156	TC32	viability	CGAGATGGAGAAGAGCAAGCAGG	TRIM16	ENSG00000221926	-0.16766182272438412	[284]	[173,275,310,179]	-3	hSpCas9	negative selection	9521779
15651413	15651436	17	-	27869803	HPAFII	viability after 27 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	0.8083226395537786	[54]	[0,91,NaN]	6	hSpCas9	negative selection	9559240
15651414	15651437	17	-	27869803	HPAFII	viability after 27 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-1.5673000002658837	[102]	[38,0,NaN]	-7	hSpCas9	negative selection	9559241
15651489	15651512	17	-	27869803	HPAFII	viability after 27 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.5116356567581147	[240]	[76,266,NaN]	4	hSpCas9	negative selection	9559242
15651413	15651436	17	-	27869803	HPAFII	viability after 15 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	1.3283670684451667	[54]	[5,236,NaN]	9	hSpCas9	negative selection	9641689
15651414	15651437	17	-	27869803	HPAFII	viability after 15 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	0.17237011271063363	[102]	[252,44,NaN]	2	hSpCas9	negative selection	9641690
15651489	15651512	17	-	27869803	HPAFII	viability after 15 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.1031406436743934	[240]	[329,245,NaN]	1	hSpCas9	negative selection	9641691
15651413	15651436	17	-	27869803	ASPC1	viability after 36 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	1.4957360902902128	[134]	[17,389,7]	9	hSpCas9	negative selection	9724138
15651414	15651437	17	-	27869803	ASPC1	viability after 36 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-0.03482748180242834	[285]	[104,113,77]	0	hSpCas9	negative selection	9724139
15651489	15651512	17	-	27869803	ASPC1	viability after 36 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.8244659437395363	[511]	[179,79,60]	-7	hSpCas9	negative selection	9724140
15651413	15651436	17	-	27869803	PATU8988S	viability after 35 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	0.5860808029609625	[23]	[18,9,NaN]	6	hSpCas9	negative selection	9806587
15651414	15651437	17	-	27869803	PATU8988S	viability after 35 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-0.19556796560717227	[238]	[107,59,NaN]	-2	hSpCas9	negative selection	9806588
15651489	15651512	17	-	27869803	PATU8988S	viability after 35 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.4638859838332789	[518]	[173,128,NaN]	-5	hSpCas9	negative selection	9806589
15651413	15651436	17	-	27869803	PATU8988S	viability after 31 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	0.5364214979778912	[23]	[12,14,NaN]	6	hSpCas9	negative selection	9889036
15651414	15651437	17	-	27869803	PATU8988S	viability after 31 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-1.0863317861157509	[238]	[54,31,NaN]	-8	hSpCas9	negative selection	9889037
15651489	15651512	17	-	27869803	PATU8988S	viability after 31 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	-0.08673301313752174	[518]	[160,237,NaN]	-1	hSpCas9	negative selection	9889038
15651413	15651436	17	-	27869803	HPAFII	viability after 35 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	0.8421880512944475	[54]	[0,104,NaN]	5	hSpCas9	negative selection	9971485
15651414	15651437	17	-	27869803	HPAFII	viability after 35 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-0.3968106607982824	[102]	[72,1,NaN]	-2	hSpCas9	negative selection	9971486
15651489	15651512	17	-	27869803	HPAFII	viability after 35 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.04525668993994616	[240]	[28,234,NaN]	0	hSpCas9	negative selection	9971487
15651413	15651436	17	-	27869803	HPAFII	viability after 31 days	GACAGCGACTCTGCAGAGCAGGG	TRIM16	ENSG00000221926	1.0010460914216945	[54]	[0,127,NaN]	7	hSpCas9	negative selection	10053934
15651414	15651437	17	-	27869803	HPAFII	viability after 31 days	GGACAGCGACTCTGCAGAGCAGG	TRIM16	ENSG00000221926	-3.1291027890492527	[102]	[8,3,NaN]	-9	hSpCas9	negative selection	10053935
15651489	15651512	17	-	27869803	HPAFII	viability after 31 days	TTCTGGGTCAGCCAGCCCAGTGG	TRIM16	ENSG00000221926	0.24260316348093575	[240]	[59,268,NaN]	1	hSpCas9	negative selection	10053936
15651441	15651464	17	-	28162770	P31FUJ	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	-0.18504907296601045	[207]	[214]	-2	hSpCas9	negative selection	10256608
15651532	15651555	17	+	28162770	P31FUJ	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	0.43324160382121013	[270]	[429]	5	hSpCas9	negative selection	10256609
15636242	15636265	17	-	28162770	P31FUJ	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	1.0473057147783567	[83]	[203]	9	hSpCas9	negative selection	10256610
15651412	15651435	17	-	28162770	P31FUJ	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	-0.1240959449718787	[114]	[123]	-1	hSpCas9	negative selection	10256611
15651557	15651580	17	+	28162770	P31FUJ	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	0.1731901552614583	[39]	[52]	1	hSpCas9	negative selection	10256612
15651499	15651522	17	+	28162770	P31FUJ	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	0.6705217761739475	[215]	[403]	7	hSpCas9	negative selection	10256613
15651473	15651496	17	-	28162770	P31FUJ	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-0.13929031849123397	[447]	[477]	-1	hSpCas9	negative selection	10256614
15651345	15651368	17	-	28162770	P31FUJ	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	0.5187418546747196	[511]	[861]	6	hSpCas9	negative selection	10256615
15651240	15651263	17	+	28162770	P31FUJ	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	0.8281658128770484	[138]	[289]	8	hSpCas9	negative selection	10256616
15651179	15651202	17	+	28162770	P31FUJ	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-0.22052387463594192	[116]	[117]	-2	hSpCas9	negative selection	10256617
15651441	15651464	17	-	28162770	TF1	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10425974
15651532	15651555	17	+	28162770	TF1	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	NaN	[NaN]	[243]	1	hSpCas9	negative selection	10425975
15636242	15636265	17	-	28162770	TF1	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10425976
15651412	15651435	17	-	28162770	TF1	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10425977
15651557	15651580	17	+	28162770	TF1	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10425978
15651499	15651522	17	+	28162770	TF1	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	NaN	[NaN]	[340]	1	hSpCas9	negative selection	10425979
15651473	15651496	17	-	28162770	TF1	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10425980
15651345	15651368	17	-	28162770	TF1	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	NaN	[NaN]	[684]	1	hSpCas9	negative selection	10425981
15651240	15651263	17	+	28162770	TF1	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	NaN	[NaN]	[272]	1	hSpCas9	negative selection	10425982
15651179	15651202	17	+	28162770	TF1	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10425983
15651441	15651464	17	-	28162770	SKM1	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	-0.5000736031346431	[67]	[84]	-4	hSpCas9	negative selection	10595340
15651532	15651555	17	+	28162770	SKM1	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	0.27421361723729754	[57]	[123]	2	hSpCas9	negative selection	10595341
15636242	15636265	17	-	28162770	SKM1	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	-1.0146467759644013	[31]	[27]	-6	hSpCas9	negative selection	10595342
15651412	15651435	17	-	28162770	SKM1	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	0.43515614147511916	[40]	[97]	4	hSpCas9	negative selection	10595343
15651557	15651580	17	+	28162770	SKM1	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-0.75787136060229	[21]	[22]	-5	hSpCas9	negative selection	10595344
15651499	15651522	17	+	28162770	SKM1	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	0.8646906896629769	[72]	[234]	7	hSpCas9	negative selection	10595345
15651473	15651496	17	-	28162770	SKM1	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	0.02599520853294457	[104]	[188]	0	hSpCas9	negative selection	10595346
15651345	15651368	17	-	28162770	SKM1	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	0.34792330342030664	[139]	[314]	3	hSpCas9	negative selection	10595347
15651240	15651263	17	+	28162770	SKM1	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	-0.5282704949652954	[30]	[37]	-4	hSpCas9	negative selection	10595348
15651179	15651202	17	+	28162770	SKM1	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-1.2814333166593026	[21]	[15]	-7	hSpCas9	negative selection	10595349
15651441	15651464	17	-	28162770	SKM1	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	-0.5000736031346431	[67]	[84]	-4	hSpCas9	negative selection	10764706
15651532	15651555	17	+	28162770	SKM1	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	0.27421361723729754	[57]	[123]	2	hSpCas9	negative selection	10764707
15636242	15636265	17	-	28162770	SKM1	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	-1.0146467759644013	[31]	[27]	-6	hSpCas9	negative selection	10764708
15651412	15651435	17	-	28162770	SKM1	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	0.43515614147511916	[40]	[97]	4	hSpCas9	negative selection	10764709
15651557	15651580	17	+	28162770	SKM1	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-0.75787136060229	[21]	[22]	-5	hSpCas9	negative selection	10764710
15651499	15651522	17	+	28162770	SKM1	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	0.8646906896629769	[72]	[234]	7	hSpCas9	negative selection	10764711
15651473	15651496	17	-	28162770	SKM1	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	0.02599520853294457	[104]	[188]	0	hSpCas9	negative selection	10764712
15651345	15651368	17	-	28162770	SKM1	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	0.34792330342030664	[139]	[314]	3	hSpCas9	negative selection	10764713
15651240	15651263	17	+	28162770	SKM1	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	-0.5282704949652954	[30]	[37]	-4	hSpCas9	negative selection	10764714
15651179	15651202	17	+	28162770	SKM1	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-1.2814333166593026	[21]	[15]	-7	hSpCas9	negative selection	10764715
15651441	15651464	17	-	28162770	PL21	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	-0.4917380901483479	[251]	[77]	-4	hSpCas9	negative selection	10934072
15651532	15651555	17	+	28162770	PL21	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	0.1631454070071185	[157]	[76]	1	hSpCas9	negative selection	10934073
15636242	15636265	17	-	28162770	PL21	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	-1.4260455489583488	[141]	[22]	-7	hSpCas9	negative selection	10934074
15651412	15651435	17	-	28162770	PL21	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	-0.15655389855871904	[104]	[40]	-1	hSpCas9	negative selection	10934075
15651557	15651580	17	+	28162770	PL21	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-0.14778368893098648	[55]	[21]	-1	hSpCas9	negative selection	10934076
15651499	15651522	17	+	28162770	PL21	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	-0.43155393657682706	[250]	[80]	-3	hSpCas9	negative selection	10934077
15651473	15651496	17	-	28162770	PL21	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-0.7529739978798441	[332]	[85]	-5	hSpCas9	negative selection	10934078
15651345	15651368	17	-	28162770	PL21	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	-0.034325639147702924	[439]	[186]	0	hSpCas9	negative selection	10934079
15651240	15651263	17	+	28162770	PL21	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	0.7426668488900798	[91]	[66]	6	hSpCas9	negative selection	10934080
15651179	15651202	17	+	28162770	PL21	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-3.136143773375112	[100]	[4]	-9	hSpCas9	negative selection	10934081
15651441	15651464	17	-	28162770	P31FUJ	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	-0.18504907296601045	[207]	[214]	-2	hSpCas9	negative selection	11103438
15651532	15651555	17	+	28162770	P31FUJ	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	0.43324160382121013	[270]	[429]	5	hSpCas9	negative selection	11103439
15636242	15636265	17	-	28162770	P31FUJ	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	1.0473057147783567	[83]	[203]	9	hSpCas9	negative selection	11103440
15651412	15651435	17	-	28162770	P31FUJ	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	-0.1240959449718787	[114]	[123]	-1	hSpCas9	negative selection	11103441
15651557	15651580	17	+	28162770	P31FUJ	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	0.1731901552614583	[39]	[52]	1	hSpCas9	negative selection	11103442
15651499	15651522	17	+	28162770	P31FUJ	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	0.6705217761739475	[215]	[403]	7	hSpCas9	negative selection	11103443
15651473	15651496	17	-	28162770	P31FUJ	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-0.13929031849123397	[447]	[477]	-1	hSpCas9	negative selection	11103444
15651345	15651368	17	-	28162770	P31FUJ	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	0.5187418546747196	[511]	[861]	6	hSpCas9	negative selection	11103445
15651240	15651263	17	+	28162770	P31FUJ	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	0.8281658128770484	[138]	[289]	8	hSpCas9	negative selection	11103446
15651179	15651202	17	+	28162770	P31FUJ	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-0.22052387463594192	[116]	[117]	-2	hSpCas9	negative selection	11103447
15651441	15651464	17	-	28162770	OCIAML5	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	-0.37931357372886576	[48]	[67]	-3	hSpCas9	negative selection	11272804
15651532	15651555	17	+	28162770	OCIAML5	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	0.860651477055532	[89]	[294]	7	hSpCas9	negative selection	11272805
15636242	15636265	17	-	28162770	OCIAML5	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	0.09730735606603502	[57]	[111]	0	hSpCas9	negative selection	11272806
15651412	15651435	17	-	28162770	OCIAML5	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	0.7043267776603883	[33]	[99]	6	hSpCas9	negative selection	11272807
15651557	15651580	17	+	28162770	OCIAML5	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	0.8791166707082034	[24]	[82]	7	hSpCas9	negative selection	11272808
15651499	15651522	17	+	28162770	OCIAML5	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	0.6240324541511254	[132]	[369]	5	hSpCas9	negative selection	11272809
15651473	15651496	17	-	28162770	OCIAML5	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-0.14916281277142368	[179]	[292]	-1	hSpCas9	negative selection	11272810
15651345	15651368	17	-	28162770	OCIAML5	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	-0.1756810423792461	[427]	[683]	-1	hSpCas9	negative selection	11272811
15651240	15651263	17	+	28162770	OCIAML5	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	-0.14424732235730742	[59]	[97]	-1	hSpCas9	negative selection	11272812
15651179	15651202	17	+	28162770	OCIAML5	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-1.085265747157028	[66]	[56]	-6	hSpCas9	negative selection	11272813
15651441	15651464	17	-	28162770	EOL1	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	0.19020764681115176	[365]	[219]	1	hSpCas9	negative selection	11442170
15651532	15651555	17	+	28162770	EOL1	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	0.3651203629565159	[223]	[151]	3	hSpCas9	negative selection	11442171
15636242	15636265	17	-	28162770	EOL1	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	-1.5511856593958633	[266]	[47]	-7	hSpCas9	negative selection	11442172
15651412	15651435	17	-	28162770	EOL1	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	0.12407923509817037	[208]	[119]	1	hSpCas9	negative selection	11442173
15651557	15651580	17	+	28162770	EOL1	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-0.79534430923673	[111]	[33]	-5	hSpCas9	negative selection	11442174
15651499	15651522	17	+	28162770	EOL1	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	-0.5236783923588821	[512]	[187]	-4	hSpCas9	negative selection	11442175
15651473	15651496	17	-	28162770	EOL1	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-0.20377632540500495	[469]	[214]	-1	hSpCas9	negative selection	11442176
15651345	15651368	17	-	28162770	EOL1	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	0.07373310036810499	[614]	[340]	0	hSpCas9	negative selection	11442177
15651240	15651263	17	+	28162770	EOL1	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	0.18758217740432825	[124]	[74]	1	hSpCas9	negative selection	11442178
15651179	15651202	17	+	28162770	EOL1	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-0.22050256123274847	[114]	[51]	-2	hSpCas9	negative selection	11442179
15651441	15651464	17	-	28162770	MOLM13	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	0.007048192652610141	[255]	[185]	0	hSpCas9	negative selection	11611536
15651532	15651555	17	+	28162770	MOLM13	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	-0.4134661219568021	[209]	[113]	-2	hSpCas9	negative selection	11611537
15636242	15636265	17	-	28162770	MOLM13	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	0.13202209569934276	[129]	[102]	0	hSpCas9	negative selection	11611538
15651412	15651435	17	-	28162770	MOLM13	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	0.7402616519577088	[153]	[185]	5	hSpCas9	negative selection	11611539
15651557	15651580	17	+	28162770	MOLM13	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-1.2976453648183983	[67]	[19]	-6	hSpCas9	negative selection	11611540
15651499	15651522	17	+	28162770	MOLM13	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	1.0237894166632722	[350]	[515]	7	hSpCas9	negative selection	11611541
15651473	15651496	17	-	28162770	MOLM13	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-0.948112163905045	[498]	[186]	-5	hSpCas9	negative selection	11611542
15651345	15651368	17	-	28162770	MOLM13	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	-0.2032425042617294	[870]	[546]	-1	hSpCas9	negative selection	11611543
15651240	15651263	17	+	28162770	MOLM13	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	-0.12164584896640174	[157]	[104]	0	hSpCas9	negative selection	11611544
15651179	15651202	17	+	28162770	MOLM13	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	0.3804265402942393	[101]	[95]	2	hSpCas9	negative selection	11611545
15651441	15651464	17	-	28162770	HEL	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	-0.2445315681388736	[282]	[152]	-2	hSpCas9	negative selection	11780902
15651532	15651555	17	+	28162770	HEL	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	0.11865857342622305	[173]	[120]	1	hSpCas9	negative selection	11780903
15636242	15636265	17	-	28162770	HEL	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	-0.6103801049683543	[173]	[72]	-4	hSpCas9	negative selection	11780904
15651412	15651435	17	-	28162770	HEL	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	-0.12428399602202905	[193]	[113]	-1	hSpCas9	negative selection	11780905
15651557	15651580	17	+	28162770	HEL	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	0.012688441750662971	[64]	[41]	0	hSpCas9	negative selection	11780906
15651499	15651522	17	+	28162770	HEL	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	1.1818474388371292	[308]	[448]	9	hSpCas9	negative selection	11780907
15651473	15651496	17	-	28162770	HEL	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-0.7002272526577926	[448]	[176]	-4	hSpCas9	negative selection	11780908
15651345	15651368	17	-	28162770	HEL	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	0.5432031584494426	[644]	[601]	4	hSpCas9	negative selection	11780909
15651240	15651263	17	+	28162770	HEL	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	0.24907498351408008	[133]	[101]	2	hSpCas9	negative selection	11780910
15651179	15651202	17	+	28162770	HEL	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-3.0987281544007903	[106]	[7]	-9	hSpCas9	negative selection	11780911
15651441	15651464	17	-	28162770	MV411	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	-1.3749996553570438	[233]	[75]	-7	hSpCas9	negative selection	11950268
15651532	15651555	17	+	28162770	MV411	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	0.2953720278464772	[147]	[152]	2	hSpCas9	negative selection	11950269
15636242	15636265	17	-	28162770	MV411	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	0.6069799374699155	[105]	[135]	5	hSpCas9	negative selection	11950270
15651412	15651435	17	-	28162770	MV411	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	0.23094942799420626	[87]	[86]	2	hSpCas9	negative selection	11950271
15651557	15651580	17	+	28162770	MV411	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	0.17343696933899855	[59]	[56]	1	hSpCas9	negative selection	11950272
15651499	15651522	17	+	28162770	MV411	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	1.0238542956677055	[201]	[345]	8	hSpCas9	negative selection	11950273
15651473	15651496	17	-	28162770	MV411	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-0.3215392457656814	[358]	[241]	-2	hSpCas9	negative selection	11950274
15651345	15651368	17	-	28162770	MV411	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	0.359912280041188	[406]	[439]	3	hSpCas9	negative selection	11950275
15651240	15651263	17	+	28162770	MV411	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	0.7031170345589651	[104]	[143]	6	hSpCas9	negative selection	11950276
15651179	15651202	17	+	28162770	MV411	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-1.083207761205696	[82]	[32]	-6	hSpCas9	negative selection	11950277
15651441	15651464	17	-	28162770	MONOMAC1	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	-0.46007125289334755	[131]	[109]	-4	hSpCas9	negative selection	12119634
15651532	15651555	17	+	28162770	MONOMAC1	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	-0.10880966404781847	[110]	[117]	-1	hSpCas9	negative selection	12119635
15636242	15636265	17	-	28162770	MONOMAC1	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	0.4092993044541697	[66]	[101]	4	hSpCas9	negative selection	12119636
15651412	15651435	17	-	28162770	MONOMAC1	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	0.8535892260104144	[55]	[115]	7	hSpCas9	negative selection	12119637
15651557	15651580	17	+	28162770	MONOMAC1	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-0.559606926444262	[44]	[34]	-5	hSpCas9	negative selection	12119638
15651499	15651522	17	+	28162770	MONOMAC1	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	0.2157015361297021	[156]	[208]	2	hSpCas9	negative selection	12119639
15651473	15651496	17	-	28162770	MONOMAC1	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-0.5482592487409541	[198]	[155]	-5	hSpCas9	negative selection	12119640
15651345	15651368	17	-	28162770	MONOMAC1	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	0.5603928496663682	[293]	[496]	5	hSpCas9	negative selection	12119641
15651240	15651263	17	+	28162770	MONOMAC1	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	0.5134565357454614	[65]	[107]	5	hSpCas9	negative selection	12119642
15651179	15651202	17	+	28162770	MONOMAC1	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-1.4100305703937521	[50]	[21]	-8	hSpCas9	negative selection	12119643
15651441	15651464	17	-	28162770	OCIAML2	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	0.17846301289871058	[32]	[206]	1	hSpCas9	negative selection	12289000
15651532	15651555	17	+	28162770	OCIAML2	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	-0.47062982524216124	[38]	[155]	-4	hSpCas9	negative selection	12289001
15636242	15636265	17	-	28162770	OCIAML2	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	-0.3153515997642502	[21]	[97]	-3	hSpCas9	negative selection	12289002
15651412	15651435	17	-	28162770	OCIAML2	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	-0.8691792017324362	[28]	[87]	-6	hSpCas9	negative selection	12289003
15651557	15651580	17	+	28162770	OCIAML2	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-0.4966250337751059	[13]	[54]	-4	hSpCas9	negative selection	12289004
15651499	15651522	17	+	28162770	OCIAML2	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	1.5433906450727735	[31]	[516]	9	hSpCas9	negative selection	12289005
15651473	15651496	17	-	28162770	OCIAML2	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	-1.144754545838136	[72]	[182]	-6	hSpCas9	negative selection	12289006
15651345	15651368	17	-	28162770	OCIAML2	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	0.5461264030834168	[106]	[865]	5	hSpCas9	negative selection	12289007
15651240	15651263	17	+	28162770	OCIAML2	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	0.7722266986540024	[14]	[141]	7	hSpCas9	negative selection	12289008
15651179	15651202	17	+	28162770	OCIAML2	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-1.7925579201295236	[19]	[31]	-8	hSpCas9	negative selection	12289009
15651441	15651464	17	-	28162770	OCIAML3	viability	GAAGCTTGGCAGGGAGACGGAGG	TRIM16	ENSG00000221926	-0.1736758413758063	[67]	[181]	-1	hSpCas9	negative selection	12458366
15651532	15651555	17	+	28162770	OCIAML3	viability	GTCTGGGCTGAGAGGGGCTGGGG	TRIM16	ENSG00000221926	0.643031556976686	[55]	[263]	6	hSpCas9	negative selection	12458367
15636242	15636265	17	-	28162770	OCIAML3	viability	GGTGTCAGAGGTCAAAGCGGTGG	TRIM16	ENSG00000221926	0.006384900966599161	[30]	[93]	0	hSpCas9	negative selection	12458368
15651412	15651435	17	-	28162770	OCIAML3	viability	ACAGCGACTCTGCAGAGCAGGGG	TRIM16	ENSG00000221926	-0.4967104389692484	[42]	[91]	-4	hSpCas9	negative selection	12458369
15651557	15651580	17	+	28162770	OCIAML3	viability	TGAGCAGTGGCCCTGGGCAGTGG	TRIM16	ENSG00000221926	-0.9419309437444698	[13]	[21]	-6	hSpCas9	negative selection	12458370
15651499	15651522	17	+	28162770	OCIAML3	viability	GGCTGACCCAGAATCTGGGCTGG	TRIM16	ENSG00000221926	0.4648860487294054	[59]	[249]	4	hSpCas9	negative selection	12458371
15651473	15651496	17	-	28162770	OCIAML3	viability	CCAGTGGAAGAAGAGGACGTGGG	TRIM16	ENSG00000221926	0.5532990584561305	[99]	[442]	5	hSpCas9	negative selection	12458372
15651345	15651368	17	-	28162770	OCIAML3	viability	TGATGACACCAGAAGAGTGAAGG	TRIM16	ENSG00000221926	0.6447792192629533	[124]	[589]	6	hSpCas9	negative selection	12458373
15651240	15651263	17	+	28162770	OCIAML3	viability	TCACTGGCTCGGTCAGCAGGTGG	TRIM16	ENSG00000221926	-0.054848829216131656	[31]	[92]	0	hSpCas9	negative selection	12458374
15651179	15651202	17	+	28162770	OCIAML3	viability	GGGCAGCAGAAGGCAGACAGTGG	TRIM16	ENSG00000221926	-0.17897014104531928	[29]	[79]	-1	hSpCas9	negative selection	12458375