Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7294
• Symbol: TXK
• Description: TXK tyrosine kinase

DataSource: http://genomecrispr.dkfz.de/#!/results/TXK

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
48094092	48094115	4	+	26472758	Jiyoye	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.9841005631616113	[119]	[178]	6	hSpCas9	negative selection	175575
48112445	48112468	4	+	26472758	Jiyoye	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	5.494638222756212	[0]	[33]	9	hSpCas9	negative selection	175576
48079955	48079978	4	-	26472758	Jiyoye	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.21652215123717378	[516]	[452]	1	hSpCas9	negative selection	175577
48112327	48112350	4	-	26472758	Jiyoye	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	1.928007544807314	[68]	[197]	8	hSpCas9	negative selection	175578
48089748	48089771	4	+	26472758	Jiyoye	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	1.6042122285654272	[81]	[187]	8	hSpCas9	negative selection	175579
48073996	48074019	4	-	26472758	Jiyoye	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	-0.11436173907364922	[88]	[61]	-1	hSpCas9	negative selection	175580
48114374	48114397	4	+	26472758	Jiyoye	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	0.7475998200106252	[123]	[156]	5	hSpCas9	negative selection	175581
48114347	48114370	4	-	26472758	Jiyoye	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	1.2739088506424092	[33]	[61]	7	hSpCas9	negative selection	175582
48113266	48113289	4	+	26472758	Jiyoye	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.15647931023532252	[162]	[136]	1	hSpCas9	negative selection	175583
48113234	48113257	4	-	26472758	Jiyoye	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	-0.4064114942632453	[57]	[32]	-3	hSpCas9	negative selection	175584
48094092	48094115	4	+	26472758	KBM7	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	-0.004025359965513703	[564,477]	[212,270]	0	hSpCas9	negative selection	366693
48112445	48112468	4	+	26472758	KBM7	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	1.1004603341005998	[98,163]	[87,179]	9	hSpCas9	negative selection	366694
48079955	48079978	4	-	26472758	KBM7	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.21322379973590944	[1718,1726]	[991,900]	2	hSpCas9	negative selection	366695
48112327	48112350	4	-	26472758	KBM7	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	-0.3297245897096453	[379,361]	[164,115]	-3	hSpCas9	negative selection	366696
48089748	48089771	4	+	26472758	KBM7	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	-0.1855041052392476	[654,547]	[244,249]	-2	hSpCas9	negative selection	366697
48073996	48074019	4	-	26472758	KBM7	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	-0.05491280628549289	[168,158]	[76,71]	0	hSpCas9	negative selection	366698
48114374	48114397	4	+	26472758	KBM7	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	-0.18679187658386287	[387,247]	[165,95]	-2	hSpCas9	negative selection	366699
48114347	48114370	4	-	26472758	KBM7	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	-0.21564951553744488	[438,448]	[107,245]	-2	hSpCas9	negative selection	366700
48113266	48113289	4	+	26472758	KBM7	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.29788544236946235	[701,577]	[270,218]	-3	hSpCas9	negative selection	366701
48113234	48113257	4	-	26472758	KBM7	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	0.28847316708606296	[173,203]	[110,108]	3	hSpCas9	negative selection	366702
48094092	48094115	4	+	26472758	Raji	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.5786038700455673	[276]	[95]	5	hSpCas9	negative selection	557811
48112445	48112468	4	+	26472758	Raji	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	0.015461045932560369	[80]	[18]	0	hSpCas9	negative selection	557812
48079955	48079978	4	-	26472758	Raji	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.5478436315323505	[674]	[228]	5	hSpCas9	negative selection	557813
48112327	48112350	4	-	26472758	Raji	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	0.4280936521042902	[236]	[73]	4	hSpCas9	negative selection	557814
48089748	48089771	4	+	26472758	Raji	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.14055039930879887	[386]	[98]	1	hSpCas9	negative selection	557815
48073996	48074019	4	-	26472758	Raji	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	1.5928103625438412	[79]	[55]	9	hSpCas9	negative selection	557816
48114374	48114397	4	+	26472758	Raji	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	-0.7339187186073423	[257]	[35]	-5	hSpCas9	negative selection	557817
48114347	48114370	4	-	26472758	Raji	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	-0.06508366063116608	[283]	[62]	0	hSpCas9	negative selection	557818
48113266	48113289	4	+	26472758	Raji	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.17717186553046183	[342]	[89]	1	hSpCas9	negative selection	557819
48113234	48113257	4	-	26472758	Raji	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	-0.6184415011874063	[85]	[12]	-5	hSpCas9	negative selection	557820
48094092	48094115	4	+	26472758	K562	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	-0.0602583241698913	[477]	[386]	0	hSpCas9	negative selection	748929
48112445	48112468	4	+	26472758	K562	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	2.4093256543421346	[63]	[286]	9	hSpCas9	negative selection	748930
48079955	48079978	4	-	26472758	K562	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.6374870135262833	[1554]	[2041]	5	hSpCas9	negative selection	748931
48112327	48112350	4	-	26472758	K562	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	0.09027672346506199	[374]	[336]	0	hSpCas9	negative selection	748932
48089748	48089771	4	+	26472758	K562	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.8646054898321196	[498]	[766]	7	hSpCas9	negative selection	748933
48073996	48074019	4	-	26472758	K562	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	1.0593073224094585	[190]	[335]	8	hSpCas9	negative selection	748934
48114374	48114397	4	+	26472758	K562	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	-0.15527822547791084	[342]	[259]	-1	hSpCas9	negative selection	748935
48114347	48114370	4	-	26472758	K562	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	0.9081353398020144	[302]	[479]	7	hSpCas9	negative selection	748936
48113266	48113289	4	+	26472758	K562	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.24100809950379487	[685]	[489]	-2	hSpCas9	negative selection	748937
48113234	48113257	4	-	26472758	K562	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	0.3388834116699393	[132]	[141]	2	hSpCas9	negative selection	748938
48067622	48067645	4	+	26627737	DLD1	viability	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	1.4623666645858688	[93]	[18,146,79]	9	hSpCas9	negative selection	825249
48071561	48071584	4	-	26627737	DLD1	viability	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	0.1119972634445158	[396]	[192,68,136]	1	hSpCas9	negative selection	825250
48076458	48076481	4	-	26627737	DLD1	viability	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	-0.4561744736663961	[300]	[79,66,59]	-4	hSpCas9	negative selection	825251
48080013	48080036	4	+	26627737	DLD1	viability	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	0.02915863138042818	[303]	[99,100,90]	0	hSpCas9	negative selection	825252
48089761	48089784	4	-	26627737	DLD1	viability	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	-0.15073733667614708	[467]	[134,74,175]	-1	hSpCas9	negative selection	825253
48134138	48134161	4	+	26627737	DLD1	viability	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	0.015702461669843015	[504]	[197,200,91]	0	hSpCas9	negative selection	825254
48067622	48067645	4	+	26627737	GBM cells	viability after 5 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.22387602986268096	[94]	[67,50]	3	hSpCas9	negative selection	907564
48071561	48071584	4	-	26627737	GBM cells	viability after 5 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	-0.06301808428079492	[186]	[104,86]	-1	hSpCas9	negative selection	907565
48076458	48076481	4	-	26627737	GBM cells	viability after 5 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.03831693155110216	[137]	[70,80]	0	hSpCas9	negative selection	907566
48080013	48080036	4	+	26627737	GBM cells	viability after 5 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.06667609432848307	[289]	[156,139]	-1	hSpCas9	negative selection	907567
48089761	48089784	4	-	26627737	GBM cells	viability after 5 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	-0.06137641531234314	[214]	[123,96]	-1	hSpCas9	negative selection	907568
48134138	48134161	4	+	26627737	GBM cells	viability after 5 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	-0.3365742040624455	[331]	[145,135]	-5	hSpCas9	negative selection	907569
48067622	48067645	4	+	26627737	GBM cells	viability after 13 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.5864543534899338	[94]	[40,106]	7	hSpCas9	negative selection	989879
48071561	48071584	4	-	26627737	GBM cells	viability after 13 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	-0.157463059470264	[186]	[101,81]	-2	hSpCas9	negative selection	989880
48076458	48076481	4	-	26627737	GBM cells	viability after 13 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.6667909578723071	[137]	[130,108]	7	hSpCas9	negative selection	989881
48080013	48080036	4	+	26627737	GBM cells	viability after 13 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.04277739661775759	[289]	[208,106]	0	hSpCas9	negative selection	989882
48089761	48089784	4	-	26627737	GBM cells	viability after 13 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	-0.020968697972061606	[214]	[125,105]	0	hSpCas9	negative selection	989883
48134138	48134161	4	+	26627737	GBM cells	viability after 13 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	-0.15978095745786075	[331]	[179,145]	-2	hSpCas9	negative selection	989884
48067622	48067645	4	+	26627737	GBM cells	viability after 21 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.25549634000410815	[94]	[58,63]	2	hSpCas9	negative selection	1072194
48071561	48071584	4	-	26627737	GBM cells	viability after 21 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	-0.8270374347420333	[186]	[50,62]	-6	hSpCas9	negative selection	1072195
48076458	48076481	4	-	26627737	GBM cells	viability after 21 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.9455247598673778	[137]	[146,141]	8	hSpCas9	negative selection	1072196
48080013	48080036	4	+	26627737	GBM cells	viability after 21 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.5064156982274588	[289]	[112,108]	-4	hSpCas9	negative selection	1072197
48089761	48089784	4	-	26627737	GBM cells	viability after 21 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	-0.011776133602923317	[214]	[130,101]	0	hSpCas9	negative selection	1072198
48134138	48134161	4	+	26627737	GBM cells	viability after 21 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	0.33801357394441994	[331]	[239,216]	3	hSpCas9	negative selection	1072199
48067622	48067645	4	+	26627737	RPE1	viability after 9 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	2.0143904345514576	[202]	[168,369]	8	hSpCas9	negative selection	1154509
48071561	48071584	4	-	26627737	RPE1	viability after 9 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	-0.10928898774522616	[860]	[193,321]	-1	hSpCas9	negative selection	1154510
48076458	48076481	4	-	26627737	RPE1	viability after 9 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.4309745755074533	[416]	[113,255]	3	hSpCas9	negative selection	1154511
48080013	48080036	4	+	26627737	RPE1	viability after 9 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	1.9542459392747713	[190]	[215,251]	8	hSpCas9	negative selection	1154512
48089761	48089784	4	-	26627737	RPE1	viability after 9 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	-0.5208060356263358	[994]	[210,224]	-4	hSpCas9	negative selection	1154513
48134138	48134161	4	+	26627737	RPE1	viability after 9 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	0.7255210657231715	[722]	[258,522]	5	hSpCas9	negative selection	1154514
48067622	48067645	4	+	26627737	RPE1	viability after 12 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	2.5358600792119095	[202]	[172,467]	9	hSpCas9	negative selection	1236824
48071561	48071584	4	-	26627737	RPE1	viability after 12 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	-0.2996077398332704	[860]	[117,261]	-2	hSpCas9	negative selection	1236825
48076458	48076481	4	-	26627737	RPE1	viability after 12 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.548502592186695	[416]	[141,186]	3	hSpCas9	negative selection	1236826
48080013	48080036	4	+	26627737	RPE1	viability after 12 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	2.1103106326158763	[190]	[172,272]	9	hSpCas9	negative selection	1236827
48089761	48089784	4	-	26627737	RPE1	viability after 12 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	-0.3372454865312098	[994]	[214,207]	-2	hSpCas9	negative selection	1236828
48134138	48134161	4	+	26627737	RPE1	viability after 12 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	1.0079132394531929	[722]	[275,511]	6	hSpCas9	negative selection	1236829
48067622	48067645	4	+	26627737	RPE1	viability after 15 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	2.7680720524140274	[202]	[268,508]	9	hSpCas9	negative selection	1319139
48071561	48071584	4	-	26627737	RPE1	viability after 15 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	-0.28010873425891364	[860]	[139,258]	-2	hSpCas9	negative selection	1319140
48076458	48076481	4	-	26627737	RPE1	viability after 15 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.0695124150617884	[416]	[135,111]	0	hSpCas9	negative selection	1319141
48080013	48080036	4	+	26627737	RPE1	viability after 15 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	1.9852530990656647	[190]	[133,290]	8	hSpCas9	negative selection	1319142
48089761	48089784	4	-	26627737	RPE1	viability after 15 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.03887835213501656	[994]	[364,215]	0	hSpCas9	negative selection	1319143
48134138	48134161	4	+	26627737	RPE1	viability after 15 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	0.7418068141076163	[722]	[284,396]	4	hSpCas9	negative selection	1319144
48067622	48067645	4	+	26627737	RPE1	viability after 18 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	2.6718269309954814	[202]	[147,563]	9	hSpCas9	negative selection	1401454
48071561	48071584	4	-	26627737	RPE1	viability after 18 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	0.0346740521555754	[860]	[179,299]	0	hSpCas9	negative selection	1401455
48076458	48076481	4	-	26627737	RPE1	viability after 18 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	-0.12309546514413583	[416]	[112,92]	0	hSpCas9	negative selection	1401456
48080013	48080036	4	+	26627737	RPE1	viability after 18 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	1.3403811823801353	[190]	[101,160]	7	hSpCas9	negative selection	1401457
48089761	48089784	4	-	26627737	RPE1	viability after 18 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	-0.7754836340668196	[994]	[152,160]	-5	hSpCas9	negative selection	1401458
48134138	48134161	4	+	26627737	RPE1	viability after 18 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	0.8057851802202564	[722]	[357,322]	5	hSpCas9	negative selection	1401459
48067622	48067645	4	+	26627737	HeLa	viability after 8 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	-0.105243936503437	[185]	[104,47,78]	-1	hSpCas9	negative selection	1483769
48071561	48071584	4	-	26627737	HeLa	viability after 8 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	0.5776849417299893	[170]	[157,170,20]	5	hSpCas9	negative selection	1483770
48076458	48076481	4	-	26627737	HeLa	viability after 8 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.2658580202266541	[271]	[184,133,118]	2	hSpCas9	negative selection	1483771
48080013	48080036	4	+	26627737	HeLa	viability after 8 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	0.04069680059666523	[383]	[199,137,182]	0	hSpCas9	negative selection	1483772
48089761	48089784	4	-	26627737	HeLa	viability after 8 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.22948268495589963	[281]	[77,178,158]	2	hSpCas9	negative selection	1483773
48134138	48134161	4	+	26627737	HeLa	viability after 8 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	0.9309852454673908	[239]	[243,249,118]	7	hSpCas9	negative selection	1483774
48067622	48067645	4	+	26627737	HeLa	viability after 12 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.3161980046164461	[185]	[115,73,99]	2	hSpCas9	negative selection	1566084
48071561	48071584	4	-	26627737	HeLa	viability after 12 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	0.9391720407113056	[170]	[121,145,136]	7	hSpCas9	negative selection	1566085
48076458	48076481	4	-	26627737	HeLa	viability after 12 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.26143723429424864	[271]	[89,133,178]	2	hSpCas9	negative selection	1566086
48080013	48080036	4	+	26627737	HeLa	viability after 12 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.33627460730722797	[383]	[122,106,148]	-3	hSpCas9	negative selection	1566087
48089761	48089784	4	-	26627737	HeLa	viability after 12 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.3551702413001156	[281]	[201,108,141]	3	hSpCas9	negative selection	1566088
48134138	48134161	4	+	26627737	HeLa	viability after 12 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	0.22835834327769866	[239]	[48,140,153]	2	hSpCas9	negative selection	1566089
48067622	48067645	4	+	26627737	HeLa	viability after 15 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.8908258827136366	[185]	[135,123,162]	6	hSpCas9	negative selection	1648399
48071561	48071584	4	-	26627737	HeLa	viability after 15 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	1.2727388802681692	[170]	[158,137,210]	8	hSpCas9	negative selection	1648400
48076458	48076481	4	-	26627737	HeLa	viability after 15 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	-1.113251180823484	[271]	[8,70,75]	-7	hSpCas9	negative selection	1648401
48080013	48080036	4	+	26627737	HeLa	viability after 15 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.7851793100223109	[383]	[101,42,129]	-6	hSpCas9	negative selection	1648402
48089761	48089784	4	-	26627737	HeLa	viability after 15 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.6463891889755502	[281]	[240,96,201]	5	hSpCas9	negative selection	1648403
48134138	48134161	4	+	26627737	HeLa	viability after 15 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	-0.5123655499534819	[239]	[60,46,99]	-4	hSpCas9	negative selection	1648404
48067622	48067645	4	+	26627737	HeLa	viability after 18 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.839246557714435	[185]	[82,100,162]	6	hSpCas9	negative selection	1730714
48071561	48071584	4	-	26627737	HeLa	viability after 18 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	1.2527679564363932	[170]	[103,111,210]	8	hSpCas9	negative selection	1730715
48076458	48076481	4	-	26627737	HeLa	viability after 18 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	-1.152476062161659	[271]	[3,57,75]	-7	hSpCas9	negative selection	1730716
48080013	48080036	4	+	26627737	HeLa	viability after 18 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.7618445867458612	[383]	[70,35,129]	-6	hSpCas9	negative selection	1730717
48089761	48089784	4	-	26627737	HeLa	viability after 18 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.6539720245861065	[281]	[162,80,201]	5	hSpCas9	negative selection	1730718
48134138	48134161	4	+	26627737	HeLa	viability after 18 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	-0.5705062206867783	[239]	[33,40,99]	-5	hSpCas9	negative selection	1730719
48067622	48067645	4	+	26627737	HCT116	viability after 6 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	-1.116743454651976	[465]	[7,47]	-6	hSpCas9	negative selection	1813029
48071561	48071584	4	-	26627737	HCT116	viability after 6 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	0.5455865377974615	[388]	[125,68]	3	hSpCas9	negative selection	1813030
48076458	48076481	4	-	26627737	HCT116	viability after 6 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	-1.8502050703499675	[394]	[13,18]	-8	hSpCas9	negative selection	1813031
48080013	48080036	4	+	26627737	HCT116	viability after 6 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-2.1399372331276134	[478]	[38,4]	-8	hSpCas9	negative selection	1813032
48089761	48089784	4	-	26627737	HCT116	viability after 6 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.8058696942592536	[273]	[122,48]	4	hSpCas9	negative selection	1813033
48134138	48134161	4	+	26627737	HCT116	viability after 6 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	-0.8600213242284634	[1089]	[183,44]	-5	hSpCas9	negative selection	1813034
48067622	48067645	4	+	26627737	HCT116	viability after 8 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	-0.060288365139557265	[159]	[64,159,28]	0	hSpCas9	negative selection	1895344
48071561	48071584	4	-	26627737	HCT116	viability after 8 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	-0.07600003236637648	[246]	[119,121,144]	-1	hSpCas9	negative selection	1895345
48076458	48076481	4	-	26627737	HCT116	viability after 8 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	-0.0445944616289532	[192]	[82,124,100]	0	hSpCas9	negative selection	1895346
48080013	48080036	4	+	26627737	HCT116	viability after 8 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.4577571601132198	[314]	[162,106,109]	-5	hSpCas9	negative selection	1895347
48089761	48089784	4	-	26627737	HCT116	viability after 8 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.3334092172799375	[189]	[178,119,97]	3	hSpCas9	negative selection	1895348
48134138	48134161	4	+	26627737	HCT116	viability after 8 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	0.017562610678851925	[336]	[181,209,171]	0	hSpCas9	negative selection	1895349
48067622	48067645	4	+	26627737	HCT116	viability after 9 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	-0.6441079838939121	[465]	[87,72]	-4	hSpCas9	negative selection	1977659
48071561	48071584	4	-	26627737	HCT116	viability after 9 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	-1.3499881193514183	[388]	[66,19]	-7	hSpCas9	negative selection	1977660
48076458	48076481	4	-	26627737	HCT116	viability after 9 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.3445939946172872	[394]	[167,106]	2	hSpCas9	negative selection	1977661
48080013	48080036	4	+	26627737	HCT116	viability after 9 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.06922043893882912	[478]	[179,75]	0	hSpCas9	negative selection	1977662
48089761	48089784	4	-	26627737	HCT116	viability after 9 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	1.9499156822349848	[273]	[199,347]	9	hSpCas9	negative selection	1977663
48134138	48134161	4	+	26627737	HCT116	viability after 9 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	-1.8641696368407024	[1089]	[89,71]	-8	hSpCas9	negative selection	1977664
48067622	48067645	4	+	26627737	HCT116	viability after 12 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.11208030509907263	[159]	[116,76,75]	1	hSpCas9	negative selection	2059974
48071561	48071584	4	-	26627737	HCT116	viability after 12 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	0.06089629107809302	[246]	[225,83,86]	0	hSpCas9	negative selection	2059975
48076458	48076481	4	-	26627737	HCT116	viability after 12 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	-0.3288341842183893	[192]	[75,93,72]	-3	hSpCas9	negative selection	2059976
48080013	48080036	4	+	26627737	HCT116	viability after 12 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.5516471382341941	[314]	[112,161,64]	-5	hSpCas9	negative selection	2059977
48089761	48089784	4	-	26627737	HCT116	viability after 12 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.327823411969369	[189]	[115,133,126]	3	hSpCas9	negative selection	2059978
48134138	48134161	4	+	26627737	HCT116	viability after 12 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	0.0023044350004609304	[336]	[123,224,188]	0	hSpCas9	negative selection	2059979
48067622	48067645	4	+	26627737	HCT116	viability after 15 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.25481475354708905	[159]	[120,157,51]	2	hSpCas9	negative selection	2142289
48071561	48071584	4	-	26627737	HCT116	viability after 15 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	-0.007613475340040143	[246]	[220,150,61]	0	hSpCas9	negative selection	2142290
48076458	48076481	4	-	26627737	HCT116	viability after 15 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.13497790308758784	[192]	[128,113,122]	1	hSpCas9	negative selection	2142291
48080013	48080036	4	+	26627737	HCT116	viability after 15 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.31479104539890224	[314]	[252,99,96]	-3	hSpCas9	negative selection	2142292
48089761	48089784	4	-	26627737	HCT116	viability after 15 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	-0.08082798308499295	[189]	[172,40,103]	-1	hSpCas9	negative selection	2142293
48134138	48134161	4	+	26627737	HCT116	viability after 15 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	-0.33530756899987973	[336]	[197,144,122]	-3	hSpCas9	negative selection	2142294
48067622	48067645	4	+	26627737	HCT116	viability after 18 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.17742444435035853	[159]	[93,96,69]	1	hSpCas9	negative selection	2224604
48071561	48071584	4	-	26627737	HCT116	viability after 18 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	-0.7369978789700221	[246]	[167,22,24]	-6	hSpCas9	negative selection	2224605
48076458	48076481	4	-	26627737	HCT116	viability after 18 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	-0.39031771342738475	[192]	[56,98,54]	-4	hSpCas9	negative selection	2224606
48080013	48080036	4	+	26627737	HCT116	viability after 18 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-1.4535187132473346	[314]	[79,43,42]	-8	hSpCas9	negative selection	2224607
48089761	48089784	4	-	26627737	HCT116	viability after 18 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.5380914871567543	[189]	[170,101,128]	4	hSpCas9	negative selection	2224608
48134138	48134161	4	+	26627737	HCT116	viability after 18 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	-0.29578118370789186	[336]	[114,149,131]	-3	hSpCas9	negative selection	2224609
48112440	48112463	4	+	24336569	HL60	viability	CTTCAGCAACCTCAGAGGGTGGG	TXK	ENSG00000074966	-2.6078319474392044	[192]	[66]	-9	hSpCas9	negative selection	2304398
48112489	48112512	4	+	24336569	HL60	viability	CGGCTGCACACGGCCCGTGTTGG	TXK	ENSG00000074966	0.1987893762536047	[582]	[1415]	2	hSpCas9	negative selection	2304399
48113206	48113229	4	+	24336569	HL60	viability	CTTGCTTCTTATTTGACAATTGG	TXK	ENSG00000074966	0.28848550912140924	[324]	[839]	2	hSpCas9	negative selection	2304400
48113217	48113240	4	+	24336569	HL60	viability	TTTGACAATTGGCTGAGCCACGG	TXK	ENSG00000074966	0.45923609991621694	[683]	[1989]	4	hSpCas9	negative selection	2304401
48113230	48113253	4	+	24336569	HL60	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.08611886289503426	[547]	[1230]	0	hSpCas9	negative selection	2304402
48113266	48113289	4	+	24336569	HL60	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	1.5218769294071146	[90]	[552]	8	hSpCas9	negative selection	2304403
48114347	48114370	4	-	24336569	HL60	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	-0.11117919529895448	[465]	[912]	-1	hSpCas9	negative selection	2304404
48114385	48114408	4	-	24336569	HL60	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.4517099625203732	[812]	[2352]	4	hSpCas9	negative selection	2304405
48134143	48134166	4	+	24336569	HL60	viability	CATCTTACTCACAGGAGGAAAGG	TXK	ENSG00000074966	0.13534728844425176	[665]	[1547]	1	hSpCas9	negative selection	2304406
48134150	48134173	4	+	24336569	HL60	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	0.2558587520527641	[521]	[1318]	2	hSpCas9	negative selection	2304407
48112440	48112463	4	+	24336569	KBM7	viability	CTTCAGCAACCTCAGAGGGTGGG	TXK	ENSG00000074966	1.2857751440649445	[79]	[531]	9	hSpCas9	negative selection	2371575
48112489	48112512	4	+	24336569	KBM7	viability	CGGCTGCACACGGCCCGTGTTGG	TXK	ENSG00000074966	0.3546827031029374	[526]	[1837]	3	hSpCas9	negative selection	2371576
48113206	48113229	4	+	24336569	KBM7	viability	CTTGCTTCTTATTTGACAATTGG	TXK	ENSG00000074966	1.9906634315340315	[105]	[1148]	9	hSpCas9	negative selection	2371577
48113217	48113240	4	+	24336569	KBM7	viability	TTTGACAATTGGCTGAGCCACGG	TXK	ENSG00000074966	-0.3780382632958054	[728]	[1529]	-3	hSpCas9	negative selection	2371578
48113230	48113253	4	+	24336569	KBM7	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	-0.006136317568696037	[784]	[2131]	0	hSpCas9	negative selection	2371579
48113266	48113289	4	+	24336569	KBM7	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.22455246704177412	[288]	[920]	2	hSpCas9	negative selection	2371580
48114347	48114370	4	-	24336569	KBM7	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	-1.04021562515546	[376]	[499]	-6	hSpCas9	negative selection	2371581
48114385	48114408	4	-	24336569	KBM7	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.6394876444132608	[642]	[2731]	6	hSpCas9	negative selection	2371582
48134143	48134166	4	+	24336569	KBM7	viability	CATCTTACTCACAGGAGGAAAGG	TXK	ENSG00000074966	0.44929580474815517	[423]	[1578]	4	hSpCas9	negative selection	2371583
48134150	48134173	4	+	24336569	KBM7	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.0648312352265438	[496]	[1295]	0	hSpCas9	negative selection	2371584
48096631	48096654	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGGCTGAGGCAGGAGAAAAG	TXK	ENSG00000074966	-0.8896445471743792	[26,0]	[0,0]	-5	dCas9-VP64	positive selection	2422138
48103923	48103946	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGTGAGCCACCACGCCCAG	TXK	ENSG00000074966	1.2080578617800355	[188,10]	[73,23]	5	dCas9-VP64	positive selection	2430188
48071977	48072000	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTCTCGCTCTGTCGCCCGGG	TXK	ENSG00000074966	-0.9628343821068377	[11,14]	[0,0]	-5	dCas9-VP64	positive selection	2442849
48096631	48096654	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGGCTGAGGCAGGAGAAAAG	TXK	ENSG00000074966	0.4958448470370793	[21,20]	[10,7]	4	dCas9-VP64	positive selection	2517393
48103923	48103946	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGTGAGCCACCACGCCCAG	TXK	ENSG00000074966	1.0270683763310697	[166,152]	[69,140]	6	dCas9-VP64	positive selection	2525443
48071977	48072000	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTCTCGCTCTGTCGCCCGGG	TXK	ENSG00000074966	-1.9576543847622316	[12,179]	[1,12]	-9	dCas9-VP64	positive selection	2538104
48089749	48089772	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCACAGCTGGGTTTAGCTACGG	TXK	ENSG00000074966	0.3273802843872802	[4,4]	[3,5]	7	hSpCas9	positive selection	3030263
48094194	48094217	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-0.7348560525946133	[3,3]	[2,0]	-8	hSpCas9	positive selection	3030264
48112294	48112317	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTAAGTGTCTTACCCCAAACGG	TXK	ENSG00000074966	-0.5577632961728447	[1,2]	[0,0]	-7	hSpCas9	positive selection	3030265
48113218	48113241	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTGACAATTGGCTGAGCCACGG	TXK	ENSG00000074966	-0.5557703861366822	[4,4]	[3,1]	-7	hSpCas9	positive selection	3030266
48089749	48089772	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCACAGCTGGGTTTAGCTACGG	TXK	ENSG00000074966	0.8474065977831075	[4,4]	[4,6]	9	hSpCas9	positive selection	3098121
48094194	48094217	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-0.11179331710137841	[3,3]	[2,0]	-2	hSpCas9	positive selection	3098122
48112294	48112317	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTAAGTGTCTTACCCCAAACGG	TXK	ENSG00000074966	0.2601551263081253	[1,1]	[1,1]	4	hSpCas9	positive selection	3098123
48113218	48113241	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTGACAATTGGCTGAGCCACGG	TXK	ENSG00000074966	0.13471652431821413	[4,4]	[4,2]	2	hSpCas9	positive selection	3098124
48114370	48114393		+	24336571	A375	resistance to PLX after 7 days	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	0.13283459265525854	[2,2]	[2,2]	4	hSpCas9	positive selection	3153640
48134150	48134173		+	24336571	A375	resistance to PLX after 7 days	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.08994042212010955	[9,9]	[9,8]	-3	hSpCas9	positive selection	3153641
48114347	48114370		-	24336571	A375	resistance to PLX after 7 days	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	-0.3739638938390948	[3,4]	[2,2]	-9	hSpCas9	positive selection	3153642
48114385	48114408		-	24336571	A375	resistance to PLX after 7 days	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.07269607129255987	[13,11]	[12,14]	2	hSpCas9	positive selection	3153644
48114370	48114393		+	24336571	A375	resistance to PLX after 14 days	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	0.7043027342103043	[2,1]	[1,1]	6	hSpCas9	positive selection	3211433
48134150	48134173		+	24336571	A375	resistance to PLX after 14 days	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.9410899904216584	[15,11]	[3,2]	-9	hSpCas9	positive selection	3211434
48114347	48114370		-	24336571	A375	resistance to PLX after 14 days	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	0.516438398344889	[2,4]	[1,2]	5	hSpCas9	positive selection	3211435
48114385	48114408		-	24336571	A375	resistance to PLX after 14 days	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.06131199776928456	[12,12]	[4,6]	0	hSpCas9	positive selection	3211437
48114370	48114393		+	24336571	A375	viability after 7 days	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-1.3557564481418574	[8]	[2,2]	-9	hSpCas9	negative selection	3269226
48134150	48134173		+	24336571	A375	viability after 7 days	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	0.03223373720704176	[10]	[9,9]	0	hSpCas9	negative selection	3269227
48114347	48114370		-	24336571	A375	viability after 7 days	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	0.2398885039477432	[3]	[3,4]	3	hSpCas9	negative selection	3269228
48114385	48114408		-	24336571	A375	viability after 7 days	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	-0.5133721963614718	[19]	[13,11]	-6	hSpCas9	negative selection	3269230
48114370	48114393		+	24336571	A375	viability after 14 days	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-1.5955732181971376	[8]	[2,1]	-9	hSpCas9	negative selection	3327019
48134150	48134173		+	24336571	A375	viability after 14 days	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	0.4877621110217787	[10]	[15,11]	6	hSpCas9	negative selection	3327020
48114347	48114370		-	24336571	A375	viability after 14 days	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	0.23861718432365664	[3]	[2,4]	3	hSpCas9	negative selection	3327021
48114385	48114408		-	24336571	A375	viability after 14 days	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	-0.564302316874237	[19]	[12,12]	-6	hSpCas9	negative selection	3327023
48114370	48114393	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.3201026165899134	[190,190]	[0,0]	-2	hSpCas9	positive selection	3399795
48134150	48134173	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	0.009398698002249677	[151,151]	[0,0]	0	hSpCas9	positive selection	3399796
48113266	48113289	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	1.2992568919117535	[372,372]	[5,5]	5	hSpCas9	positive selection	3399797
48089749	48089772	4	-	26780180	HT29	viability (Avana library 4 designs)	GCCACAGCTGGGTTTAGCTACGG	TXK	ENSG00000074966	0.3998856102863	[]	[]	1	hSpCas9	negative selection	3469187
48094194	48094217	4	-	26780180	HT29	viability (Avana library 4 designs)	TCTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	1.81011261692625	[]	[]	7	hSpCas9	negative selection	3469188
48112293	48112316	4	+	26780180	HT29	viability (Avana library 4 designs)	TGTAAGTGTCTTACCCCAAACGG	TXK	ENSG00000074966	0.41669132233797	[]	[]	1	hSpCas9	negative selection	3469189
48113217	48113240	4	+	26780180	HT29	viability (Avana library 4 designs)	TTTGACAATTGGCTGAGCCACGG	TXK	ENSG00000074966	-0.243016522617568	[]	[]	-4	hSpCas9	negative selection	3469190
48094194	48094217	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-1.00479616782622	[]	[]	-1	hSpCas9	negative selection	3574304
48089749	48089772	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCACAGCTGGGTTTAGCTACGG	TXK	ENSG00000074966	3.39795288965825	[]	[]	5	hSpCas9	negative selection	3574305
48113217	48113240	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGACAATTGGCTGAGCCACGG	TXK	ENSG00000074966	2.26054952174643	[]	[]	3	hSpCas9	negative selection	3574306
48112293	48112316	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTAAGTGTCTTACCCCAAACGG	TXK	ENSG00000074966	-1.33190932088737	[]	[]	-2	hSpCas9	negative selection	3574307
48114385	48114408	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	-1.49100207840664	[]	[]	-2	hSpCas9	negative selection	3574308
48112445	48112468	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	5.53852204427532	[]	[]	8	hSpCas9	negative selection	3574309
48094194	48094217	4	-	26780180	A375	viability (Avana lentiGuide)	TCTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	1.04210796929591	[]	[]	1	hSpCas9	negative selection	3682963
48089749	48089772	4	-	26780180	A375	viability (Avana lentiGuide)	GCCACAGCTGGGTTTAGCTACGG	TXK	ENSG00000074966	-4.68452867229544	[]	[]	-7	hSpCas9	negative selection	3682964
48113217	48113240	4	+	26780180	A375	viability (Avana lentiGuide)	TTTGACAATTGGCTGAGCCACGG	TXK	ENSG00000074966	3.02576780922143	[]	[]	3	hSpCas9	negative selection	3682965
48112293	48112316	4	+	26780180	A375	viability (Avana lentiGuide)	TGTAAGTGTCTTACCCCAAACGG	TXK	ENSG00000074966	5.72051609945312	[]	[]	5	hSpCas9	negative selection	3682966
48114385	48114408	4	-	26780180	A375	viability (Avana lentiGuide)	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	-0.845354822062832	[]	[]	-1	hSpCas9	negative selection	3682967
48112445	48112468	4	+	26780180	A375	viability (Avana lentiGuide)	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	-2.87602244943323	[]	[]	-5	hSpCas9	negative selection	3682968
48094194	48094217	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-0.2998099190273829	[5]	[4,4]	-4	hSpCas9	positive selection	3791570
48089749	48089772	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCACAGCTGGGTTTAGCTACGG	TXK	ENSG00000074966	0.13920193075456602	[6]	[7,5]	3	hSpCas9	positive selection	3791571
48113217	48113240	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGACAATTGGCTGAGCCACGG	TXK	ENSG00000074966	0.15486248065781433	[6]	[6,6]	4	hSpCas9	positive selection	3791572
48112293	48112316	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTAAGTGTCTTACCCCAAACGG	TXK	ENSG00000074966	-0.2017743697344434	[5]	[5,3]	-3	hSpCas9	positive selection	3791573
48114385	48114408	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	-0.3516651973276349	[6]	[4,4]	-5	hSpCas9	positive selection	3791574
48112445	48112468	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	0.28247941248494096	[5]	[6,6]	7	hSpCas9	positive selection	3791575
48094194	48094217	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-0.07534677739930201	[5]	[4,4]	-1	hSpCas9	positive selection	3900177
48089749	48089772	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCACAGCTGGGTTTAGCTACGG	TXK	ENSG00000074966	-0.0880719288923047	[6]	[4,4]	-1	hSpCas9	positive selection	3900178
48113217	48113240	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGACAATTGGCTGAGCCACGG	TXK	ENSG00000074966	-0.1957494047442751	[6]	[2,6]	-3	hSpCas9	positive selection	3900179
48112293	48112316	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTAAGTGTCTTACCCCAAACGG	TXK	ENSG00000074966	0.3468460161222586	[4]	[3,5]	8	hSpCas9	positive selection	3900180
48114385	48114408	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	-0.3435816171830324	[5]	[4,2]	-4	hSpCas9	positive selection	3900181
48112445	48112468	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	0.16385438714334216	[5]	[4,5]	4	hSpCas9	positive selection	3900182
48113240	48113263	4	-	26780180	A375	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	1.43213704905908	[]	[]	8	hSpCas9	negative selection	4009286
48114370	48114393	4	+	26780180	A375	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	1.97009442510678	[]	[]	9	hSpCas9	negative selection	4009287
48134150	48134173	4	+	26780180	A375	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	1.79639888614779	[]	[]	9	hSpCas9	negative selection	4009288
48113266	48113289	4	+	26780180	A375	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	1.36321413726484	[]	[]	7	hSpCas9	negative selection	4009289
48113230	48113253	4	+	26780180	A375	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.88656283160838	[]	[]	4	hSpCas9	negative selection	4009290
48114385	48114408	4	-	26780180	A375	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.931748972947973	[]	[]	4	hSpCas9	negative selection	4009291
48113240	48113263	4	-	26780180	HT29	viability (GeCKOv2 library)	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	2.72522530039582	[]	[]	9	hSpCas9	negative selection	4117252
48114370	48114393	4	+	26780180	HT29	viability (GeCKOv2 library)	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	2.17313913859506	[]	[]	9	hSpCas9	negative selection	4117253
48134150	48134173	4	+	26780180	HT29	viability (GeCKOv2 library)	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	1.85607514415177	[]	[]	8	hSpCas9	negative selection	4117254
48113266	48113289	4	+	26780180	HT29	viability (GeCKOv2 library)	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.260728022626496	[]	[]	0	hSpCas9	negative selection	4117255
48113230	48113253	4	+	26780180	HT29	viability (GeCKOv2 library)	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	1.83810589216945	[]	[]	8	hSpCas9	negative selection	4117256
48114385	48114408	4	-	26780180	HT29	viability (GeCKOv2 library)	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.653767468070762	[]	[]	2	hSpCas9	negative selection	4117257
48114370	48114393	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.15826499325753696	[1]	[1,0]	-4	hSpCas9	positive selection	4180290
48134150	48134173	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.44437801417669176	[2]	[0,1]	-8	hSpCas9	positive selection	4180291
48114347	48114370	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	-0.35444093514816366	[1]	[0,0]	-7	hSpCas9	positive selection	4180292
48114385	48114408	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	-0.18951088434844557	[3]	[1,2]	-4	hSpCas9	positive selection	4180294
48114370	48114393	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	0.788924783754611	[3]	[0,3,0,3]	5	hSpCas9	positive selection	4244312
48134150	48134173	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.4481292549526532	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4244313
48114347	48114370	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	0.8460368400581331	[0]	[0,0,0,0]	5	hSpCas9	positive selection	4244314
48114385	48114408	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	1.193368296961782	[4]	[0,3,6,5]	8	hSpCas9	positive selection	4244316
48113240	48113263	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.638880762357104	[3]	[3,4]	9	hSpCas9	positive selection	4306006
48113230	48113253	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.021808091018215237	[3]	[3,1]	0	hSpCas9	positive selection	4306007
48114385	48114408	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.28235148566499746	[4]	[3,4]	5	hSpCas9	positive selection	4306008
48114370	48114393	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.22281256523991053	[2]	[2,0]	-4	hSpCas9	positive selection	4370255
48134150	48134173	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.07259599002999154	[3]	[3,1]	-1	hSpCas9	positive selection	4370256
48113266	48113289	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.06906402575444137	[3]	[3,2]	1	hSpCas9	positive selection	4370257
48113240	48113262	4	-	27760321	OCIAML3	viability	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.21717034558255155	[732,533]	[468,360]	-2	hSpCas9	negative selection	4451392
48089749	48089771	4	+	27760321	OCIAML3	viability	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	-0.4211349274902521	[633,494]	[211,477]	-4	hSpCas9	negative selection	4451393
48089794	48089816	4	-	27760321	OCIAML3	viability	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	-0.31155687268782023	[494,410]	[186,410]	-3	hSpCas9	negative selection	4451394
48094092	48094114	4	+	27760321	OCIAML3	viability	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	-0.41620728703505794	[142,136]	[56,114]	-4	hSpCas9	negative selection	4451395
48094194	48094216	4	-	27760321	OCIAML3	viability	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-0.04693029046617214	[210,200]	[143,171]	0	hSpCas9	negative selection	4451396
48113240	48113262	4	-	27760321	OCIAML2	viability	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.12982256964165734	[732,533]	[377,576]	-2	hSpCas9	negative selection	4534855
48089749	48089771	4	+	27760321	OCIAML2	viability	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.22568687089220635	[633,494]	[500,568]	3	hSpCas9	negative selection	4534856
48089794	48089816	4	-	27760321	OCIAML2	viability	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	-0.08969842034064812	[494,410]	[297,401]	-1	hSpCas9	negative selection	4534857
48094092	48094114	4	+	27760321	OCIAML2	viability	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	0.5421458761206155	[142,136]	[140,196]	7	hSpCas9	negative selection	4534858
48094194	48094216	4	-	27760321	OCIAML2	viability	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	0.33096755183213755	[210,200]	[142,297]	4	hSpCas9	negative selection	4534859
48113240	48113262	4	-	27760321	MV411	viability	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-1.5104530243510856	[732,533]	[54,280]	-7	hSpCas9	negative selection	4618318
48089749	48089771	4	+	27760321	MV411	viability	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.6924626766621562	[633,494]	[706,433]	5	hSpCas9	negative selection	4618319
48089794	48089816	4	-	27760321	MV411	viability	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	-0.7376862795258282	[494,410]	[52,366]	-5	hSpCas9	negative selection	4618320
48094092	48094114	4	+	27760321	MV411	viability	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	-0.15020614031669433	[142,136]	[56,122]	-1	hSpCas9	negative selection	4618321
48094194	48094216	4	-	27760321	MV411	viability	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-1.841449387928988	[210,200]	[15,70]	-8	hSpCas9	negative selection	4618322
48113240	48113262	4	-	27760321	HL60	viability	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.2234405687782211	[732,533]	[454,421]	-3	hSpCas9	negative selection	4701781
48089749	48089771	4	+	27760321	HL60	viability	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	-0.13653041920841574	[633,494]	[453,376]	-1	hSpCas9	negative selection	4701782
48089794	48089816	4	-	27760321	HL60	viability	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	0.11154890825239153	[494,410]	[366,430]	1	hSpCas9	negative selection	4701783
48094092	48094114	4	+	27760321	HL60	viability	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	-0.44836204895512743	[142,136]	[81,85]	-5	hSpCas9	negative selection	4701784
48094194	48094216	4	-	27760321	HL60	viability	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	0.3201611212201054	[210,200]	[155,267]	4	hSpCas9	negative selection	4701785
48113240	48113262	4	-	27760321	HT1080	viability	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-1.353366266674483	[533,416]	[55,93]	-5	hSpCas9	negative selection	4785244
48089749	48089771	4	+	27760321	HT1080	viability	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.13815925180536903	[494,385]	[226,155]	0	hSpCas9	negative selection	4785245
48089794	48089816	4	-	27760321	HT1080	viability	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	-1.430733791849772	[410,320]	[76,28]	-5	hSpCas9	negative selection	4785246
48094092	48094114	4	+	27760321	HT1080	viability	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	1.4419430215546833	[136,106]	[111,153]	7	hSpCas9	negative selection	4785247
48094194	48094216	4	-	27760321	HT1080	viability	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-2.131770981719776	[200,156]	[21,9]	-6	hSpCas9	negative selection	4785248
48113240	48113262	4	-	27760321	HT29	viability after 7 days	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.2359682091631571	[533,416]	[523,312,713]	-3	hSpCas9	negative selection	4868707
48089749	48089771	4	+	27760321	HT29	viability after 7 days	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.3272193402566278	[494,385]	[871,617,664]	5	hSpCas9	negative selection	4868708
48089794	48089816	4	-	27760321	HT29	viability after 7 days	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	0.06177222375551542	[410,320]	[441,633,392]	0	hSpCas9	negative selection	4868709
48094092	48094114	4	+	27760321	HT29	viability after 7 days	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	-0.7899607219931579	[136,106]	[83,61,123]	-8	hSpCas9	negative selection	4868710
48094194	48094216	4	-	27760321	HT29	viability after 7 days	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-0.5497234766403414	[200,156]	[306,97,89]	-7	hSpCas9	negative selection	4868711
48113240	48113262	4	-	27760321	HT29	viability after 25 days	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.4600657488482133	[533,416]	[351,407,430]	-4	hSpCas9	negative selection	4952170
48089749	48089771	4	+	27760321	HT29	viability after 25 days	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.755775882759557	[494,385]	[831,848,870]	8	hSpCas9	negative selection	4952171
48089794	48089816	4	-	27760321	HT29	viability after 25 days	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	0.5014028744911259	[410,320]	[694,481,591]	5	hSpCas9	negative selection	4952172
48094092	48094114	4	+	27760321	HT29	viability after 25 days	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	0.16511044976553868	[136,106]	[93,124,264]	1	hSpCas9	negative selection	4952173
48094194	48094216	4	-	27760321	HT29	viability after 25 days	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-0.5513439756909888	[200,156]	[121,120,180]	-5	hSpCas9	negative selection	4952174
48113240	48113262	4	-	27760321	HT29	viability after 22 days	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.7736503452784738	[533,416]	[222,349,394]	-6	hSpCas9	negative selection	5035633
48089749	48089771	4	+	27760321	HT29	viability after 22 days	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.9294444295642584	[494,385]	[1189,1000,709]	9	hSpCas9	negative selection	5035634
48089794	48089816	4	-	27760321	HT29	viability after 22 days	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	0.581538991237386	[410,320]	[781,640,470]	6	hSpCas9	negative selection	5035635
48094092	48094114	4	+	27760321	HT29	viability after 22 days	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	-0.6791567119489392	[136,106]	[2,128,134]	-5	hSpCas9	negative selection	5035636
48094194	48094216	4	-	27760321	HT29	viability after 22 days	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-0.6615278829350213	[200,156]	[179,96,113]	-5	hSpCas9	negative selection	5035637
48113240	48113262	4	-	27760321	HT29	viability after 19 days	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.12732771191722042	[533,416]	[612,490,404]	-1	hSpCas9	negative selection	5119096
48089749	48089771	4	+	27760321	HT29	viability after 19 days	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.5883359154017676	[494,385]	[1106,622,584]	6	hSpCas9	negative selection	5119097
48089794	48089816	4	-	27760321	HT29	viability after 19 days	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	0.48658763498798013	[410,320]	[646,652,469]	5	hSpCas9	negative selection	5119098
48094092	48094114	4	+	27760321	HT29	viability after 19 days	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	1.1476894260856407	[136,106]	[125,202,568]	9	hSpCas9	negative selection	5119099
48094194	48094216	4	-	27760321	HT29	viability after 19 days	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-0.08107240317410858	[200,156]	[131,139,297]	0	hSpCas9	negative selection	5119100
48113240	48113262	4	-	27760321	HT29	viability after 16 days	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.5997640001955602	[533,416]	[333,254,464]	-5	hSpCas9	negative selection	5202559
48089749	48089771	4	+	27760321	HT29	viability after 16 days	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.5136048065966762	[494,385]	[767,572,778]	6	hSpCas9	negative selection	5202560
48089794	48089816	4	-	27760321	HT29	viability after 16 days	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	0.41583802420596794	[410,320]	[673,541,434]	5	hSpCas9	negative selection	5202561
48094092	48094114	4	+	27760321	HT29	viability after 16 days	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	0.2285743696827618	[136,106]	[114,141,218]	2	hSpCas9	negative selection	5202562
48094194	48094216	4	-	27760321	HT29	viability after 16 days	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-0.3545582370370246	[200,156]	[246,57,175]	-4	hSpCas9	negative selection	5202563
48113240	48113262	4	-	27760321	HT29	viability after 13 days	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.359170359852433	[533,416]	[487,405,397]	-4	hSpCas9	negative selection	5286022
48089749	48089771	4	+	27760321	HT29	viability after 13 days	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.4737681134612426	[494,385]	[847,596,684]	6	hSpCas9	negative selection	5286023
48089794	48089816	4	-	27760321	HT29	viability after 13 days	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	0.3636296950957615	[410,320]	[641,574,428]	4	hSpCas9	negative selection	5286024
48094092	48094114	4	+	27760321	HT29	viability after 13 days	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	-0.27141742256876444	[136,106]	[83,118,146]	-3	hSpCas9	negative selection	5286025
48094194	48094216	4	-	27760321	HT29	viability after 13 days	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-0.258337775149476	[200,156]	[221,180,120]	-3	hSpCas9	negative selection	5286026
48113240	48113262	4	-	27760321	HT29	viability after 10 days	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.5740902878002714	[533,416]	[273,467,454]	-6	hSpCas9	negative selection	5369485
48089749	48089771	4	+	27760321	HT29	viability after 10 days	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.48438534489284935	[494,385]	[859,667,776]	6	hSpCas9	negative selection	5369486
48089794	48089816	4	-	27760321	HT29	viability after 10 days	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	0.24735132748110725	[410,320]	[371,672,584]	3	hSpCas9	negative selection	5369487
48094092	48094114	4	+	27760321	HT29	viability after 10 days	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	0.004006487429222272	[136,106]	[147,89,216]	0	hSpCas9	negative selection	5369488
48094194	48094216	4	-	27760321	HT29	viability after 10 days	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-0.8856111363850745	[200,156]	[138,134,89]	-7	hSpCas9	negative selection	5369489
48113240	48113262	4	-	27760321	MOLM13	viability	AAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.7476268853740063	[732,533]	[972,271]	5	hSpCas9	negative selection	5452948
48089749	48089771	4	+	27760321	MOLM13	viability	CCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.414383766689782	[633,494]	[413,427]	3	hSpCas9	negative selection	5452949
48089794	48089816	4	-	27760321	MOLM13	viability	CTCGTCTCCGATATCCAGTTGG	TXK	ENSG00000074966	0.7612966123459894	[494,410]	[641,251]	5	hSpCas9	negative selection	5452950
48094092	48094114	4	+	27760321	MOLM13	viability	GGTGATACCAGATTAACTCAGG	TXK	ENSG00000074966	1.1730600784596388	[142,136]	[179,176]	8	hSpCas9	negative selection	5452951
48094194	48094216	4	-	27760321	MOLM13	viability	CTTGATTGTAGAAGTACGGAGG	TXK	ENSG00000074966	-3.75485882266478	[210,200]	[6,9]	-9	hSpCas9	negative selection	5452952
48114097	48114120	4	+	27661255	K562	viability	GTGGAGAACAATGCCGCACACGG	TXK	ENSG00000074966	-0.2235283533930566	[791,921]	[635,540]	-6	dCas9-KRAB	negative selection	5520796
48114144	48114167	4	+	27661255	K562	viability	GAAATCTAAAGGATCAGGAAAGG	TXK	ENSG00000074966	-0.003436020085437863	[776,1016]	[773,657]	0	dCas9-KRAB	negative selection	5520797
48114449	48114472	4	+	27661255	K562	viability	GATATTGAGGGAGTCTCTAAGGG	TXK	ENSG00000074966	0.147177293009781	[2370,2778]	[2415,2147]	5	dCas9-KRAB	negative selection	5520798
48113240	48113263	4	-	27260156	BXPC3	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.2693206605503444	[500]	[625,458,621,851]	6	hSpCas9	negative selection	5578466
48113230	48113253	4	+	27260156	BXPC3	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	-0.017976910986212846	[655]	[604,577,712,843]	0	hSpCas9	negative selection	5578467
48114385	48114408	4	-	27260156	BXPC3	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.0921159939381806	[1213]	[1130,1333,1330,1670]	2	hSpCas9	negative selection	5578468
48114370	48114393	4	+	27260156	BXPC3	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.4104826189314335	[433]	[347,274,382,363]	-7	hSpCas9	negative selection	5642715
48134150	48134173	4	+	27260156	BXPC3	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.3127335884520731	[783]	[591,664,697,691]	-6	hSpCas9	negative selection	5642716
48113266	48113289	4	+	27260156	BXPC3	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.3890225589770019	[730]	[798,817,1212,1231]	8	hSpCas9	negative selection	5642717
48113240	48113263	4	-	27260156	A673	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.06944709778357826	[500]	[684,577,523,514]	-2	hSpCas9	negative selection	5699717
48113230	48113253	4	+	27260156	A673	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.34813606081586057	[655]	[891,892,1001,1223]	7	hSpCas9	negative selection	5699718
48114385	48114408	4	-	27260156	A673	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.2574287442995682	[1213]	[1865,1619,1588,1919]	6	hSpCas9	negative selection	5699719
48114370	48114393	4	+	27260156	A673	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.21881605252477365	[433]	[467,405,404,518]	-5	hSpCas9	negative selection	5763966
48134150	48134173	4	+	27260156	A673	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.26627062459657475	[783]	[905,721,742,773]	-6	hSpCas9	negative selection	5763967
48113266	48113289	4	+	27260156	A673	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.32000020805879925	[730]	[1179,1024,1196,982]	7	hSpCas9	negative selection	5763968
48113240	48113263	4	-	27260156	A375	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.4061031452434459	[500]	[755,801,822,726]	6	hSpCas9	negative selection	5820968
48113230	48113253	4	+	27260156	A375	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.49990554318476177	[655]	[1114,1159,1197,890]	7	hSpCas9	negative selection	5820969
48114385	48114408	4	-	27260156	A375	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.05796413069460038	[1213]	[1198,1798,1703,1264]	0	hSpCas9	negative selection	5820970
48114370	48114393	4	+	27260156	A375	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.2764927446226509	[433]	[514,738,297,192]	-4	hSpCas9	negative selection	5885217
48134150	48134173	4	+	27260156	A375	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.604244119868563	[783]	[450,836,754,417]	-7	hSpCas9	negative selection	5885218
48113266	48113289	4	+	27260156	A375	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.12890399006466213	[730]	[972,1234,788,792]	1	hSpCas9	negative selection	5885219
48113240	48113263	4	-	27260156	COLO741	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.07729917995966566	[500]	[693,621,516]	-2	hSpCas9	negative selection	5942219
48113230	48113253	4	+	27260156	COLO741	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.01652326919671454	[655]	[1149,908,531]	0	hSpCas9	negative selection	5942220
48114385	48114408	4	-	27260156	COLO741	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.10906102263936579	[1213]	[1900,1474,1658]	2	hSpCas9	negative selection	5942221
48114370	48114393	4	+	27260156	COLO741	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.15884256522290446	[433]	[574,597,334]	-3	hSpCas9	negative selection	6006468
48134150	48134173	4	+	27260156	COLO741	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.548283309218486	[783]	[657,829,571]	-8	hSpCas9	negative selection	6006469
48113266	48113289	4	+	27260156	COLO741	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.40365350728007476	[730]	[1529,1070,1134]	8	hSpCas9	negative selection	6006470
48113240	48113263	4	-	27260156	CAL120	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.008884643617402085	[500]	[647,547,665]	0	hSpCas9	negative selection	6063470
48113230	48113253	4	+	27260156	CAL120	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.14023301327798443	[655]	[909,882,906]	2	hSpCas9	negative selection	6063471
48114385	48114408	4	-	27260156	CAL120	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.2995388402145762	[1213]	[1712,1867,1971]	4	hSpCas9	negative selection	6063472
48114370	48114393	4	+	27260156	CAL120	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.15520091089536475	[433]	[214,874,326]	-2	hSpCas9	negative selection	6127719
48134150	48134173	4	+	27260156	CAL120	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.2810506271579678	[783]	[895,700,824]	-4	hSpCas9	negative selection	6127720
48113266	48113289	4	+	27260156	CAL120	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.1717476951916208	[730]	[1246,892,967]	2	hSpCas9	negative selection	6127721
48113240	48113263	4	-	27260156	CADOES1	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.0902493365188337	[500]	[448,363,571,602]	1	hSpCas9	negative selection	6184721
48113230	48113253	4	+	27260156	CADOES1	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.037654590628677154	[655]	[945,632,509,406]	0	hSpCas9	negative selection	6184722
48114385	48114408	4	-	27260156	CADOES1	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.26004675821279144	[1213]	[1563,1206,1477,1150]	4	hSpCas9	negative selection	6184723
48114370	48114393	4	+	27260156	CADOES1	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.23105203743655417	[433]	[377,342,324,328]	-4	hSpCas9	negative selection	6248970
48134150	48134173	4	+	27260156	CADOES1	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.3283497322505197	[783]	[529,621,594,575]	-5	hSpCas9	negative selection	6248971
48113266	48113289	4	+	27260156	CADOES1	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.08345202436187882	[730]	[676,669,620,920]	1	hSpCas9	negative selection	6248972
48113240	48113263	4	-	27260156	EWS502	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.03330534359853269	[500]	[547,561,527,421]	0	hSpCas9	negative selection	6305972
48113230	48113253	4	+	27260156	EWS502	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.13361694596919194	[655]	[869,663,798,699]	2	hSpCas9	negative selection	6305973
48114385	48114408	4	-	27260156	EWS502	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.1979209966562343	[1213]	[1149,1541,1746,1496]	3	hSpCas9	negative selection	6305974
48114370	48114393	4	+	27260156	EWS502	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	0.011700877163336662	[433]	[492,531,371,445]	0	hSpCas9	negative selection	6370221
48134150	48134173	4	+	27260156	EWS502	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.6061533346765684	[783]	[488,422,503,792]	-7	hSpCas9	negative selection	6370222
48113266	48113289	4	+	27260156	EWS502	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.1963370580393562	[730]	[835,940,869,902]	3	hSpCas9	negative selection	6370223
48113240	48113263	4	-	27260156	EW8	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.004643463081326918	[500]	[408,390,362,461]	0	hSpCas9	negative selection	6427223
48113230	48113253	4	+	27260156	EW8	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.10641232831933045	[655]	[566,689,517,521]	2	hSpCas9	negative selection	6427224
48114385	48114408	4	-	27260156	EW8	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.186876042079809	[1213]	[1466,1073,814,1209]	3	hSpCas9	negative selection	6427225
48114370	48114393	4	+	27260156	EW8	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.2604080316750339	[433]	[243,334,241,355]	-5	hSpCas9	negative selection	6491472
48134150	48134173	4	+	27260156	EW8	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.33145594224388875	[783]	[652,588,334,486]	-6	hSpCas9	negative selection	6491473
48113266	48113289	4	+	27260156	EW8	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.3577174546781595	[730]	[816,913,686,635]	6	hSpCas9	negative selection	6491474
48113240	48113263	4	-	27260156	CORL105	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.14404627849779678	[500]	[712,605,614,655]	2	hSpCas9	negative selection	6548474
48113230	48113253	4	+	27260156	CORL105	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.16522492690703716	[655]	[1002,587,1004,880]	3	hSpCas9	negative selection	6548475
48114385	48114408	4	-	27260156	CORL105	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.176882700255661	[1213]	[1557,1552,1501,1794]	3	hSpCas9	negative selection	6548476
48114370	48114393	4	+	27260156	CORL105	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.0893483505446057	[433]	[527,369,591,441]	-2	hSpCas9	negative selection	6612723
48134150	48134173	4	+	27260156	CORL105	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.6739137386875074	[783]	[681,562,379,648]	-8	hSpCas9	negative selection	6612724
48113266	48113289	4	+	27260156	CORL105	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.0433298845898864	[730]	[872,814,982,872]	0	hSpCas9	negative selection	6612725
48113240	48113263	4	-	27260156	HS294T	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.5731065053967482	[500]	[274,477,167,212]	7	hSpCas9	negative selection	6669725
48113230	48113253	4	+	27260156	HS294T	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.6082658298522143	[655]	[270,676,224,370]	7	hSpCas9	negative selection	6669726
48114385	48114408	4	-	27260156	HS294T	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.13667840744846416	[1213]	[425,482,583,591]	1	hSpCas9	negative selection	6669727
48114370	48114393	4	+	27260156	HS294T	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	0.13609639816140945	[433]	[227,126,183,197]	1	hSpCas9	negative selection	6733974
48134150	48134173	4	+	27260156	HS294T	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.9862584487868297	[783]	[128,178,101,212]	-8	hSpCas9	negative selection	6733975
48113266	48113289	4	+	27260156	HS294T	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.21017897704674882	[730]	[282,299,301,446]	3	hSpCas9	negative selection	6733976
48113240	48113263	4	-	27260156	HCC44	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.04961441308720008	[500]	[730,461,583,446]	-1	hSpCas9	negative selection	6790976
48113230	48113253	4	+	27260156	HCC44	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	-0.3476107671014294	[655]	[578,561,801,429]	-5	hSpCas9	negative selection	6790977
48114385	48114408	4	-	27260156	HCC44	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	-0.12808155148586664	[1213]	[1286,1062,1157,1511]	-2	hSpCas9	negative selection	6790978
48114370	48114393	4	+	27260156	HCC44	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.1514319420290468	[433]	[772,267,488,301]	-2	hSpCas9	negative selection	6855225
48134150	48134173	4	+	27260156	HCC44	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.4728131161562473	[783]	[736,555,933,402]	-6	hSpCas9	negative selection	6855226
48113266	48113289	4	+	27260156	HCC44	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.23485789130461465	[730]	[894,1048,1030,902]	4	hSpCas9	negative selection	6855227
48113240	48113263	4	-	27260156	G402	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.15725189999930544	[500]	[751,574,523,378]	-2	hSpCas9	negative selection	6912227
48113230	48113253	4	+	27260156	G402	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	-0.31115627230591353	[655]	[615,586,392,958]	-4	hSpCas9	negative selection	6912228
48114385	48114408	4	-	27260156	G402	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.07680815817254838	[1213]	[1584,1940,1571,1188]	1	hSpCas9	negative selection	6912229
48114370	48114393	4	+	27260156	G402	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.02111154508396955	[433]	[434,338,738,547]	0	hSpCas9	negative selection	6976476
48134150	48134173	4	+	27260156	G402	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.4875050822315553	[783]	[880,432,916,517]	-6	hSpCas9	negative selection	6976477
48113266	48113289	4	+	27260156	G402	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.01816482207360892	[730]	[1361,998,493,829]	0	hSpCas9	negative selection	6976478
48113240	48113263	4	-	27260156	L33	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.2123676913722623	[500]	[442,266,410,576]	4	hSpCas9	negative selection	7033478
48113230	48113253	4	+	27260156	L33	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.1711010352054051	[655]	[763,286,447,775]	4	hSpCas9	negative selection	7033479
48114385	48114408	4	-	27260156	L33	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.14323832900410638	[1213]	[1502,462,814,1427]	3	hSpCas9	negative selection	7033480
48114370	48114393	4	+	27260156	L33	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	0.017999225162323024	[433]	[455,153,252,521]	0	hSpCas9	negative selection	7097727
48134150	48134173	4	+	27260156	L33	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.587299730828655	[783]	[405,185,437,533]	-8	hSpCas9	negative selection	7097728
48113266	48113289	4	+	27260156	L33	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.28852493861206263	[730]	[811,355,565,990]	6	hSpCas9	negative selection	7097729
48113240	48113263	4	-	27260156	K562	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.4633297346946815	[500]	[523,471,1215,263]	6	hSpCas9	negative selection	7154729
48113230	48113253	4	+	27260156	K562	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	-0.03722482421251522	[655]	[569,623,460,609]	0	hSpCas9	negative selection	7154730
48114385	48114408	4	-	27260156	K562	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.18289231369568504	[1213]	[1480,1148,1231,1060]	2	hSpCas9	negative selection	7154731
48114370	48114393	4	+	27260156	K562	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.22195555615870433	[433]	[568,245,211,309]	-3	hSpCas9	negative selection	7218978
48134150	48134173	4	+	27260156	K562	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.8780337868351548	[783]	[422,255,585,258]	-7	hSpCas9	negative selection	7218979
48113266	48113289	4	+	27260156	K562	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.6607163450928063	[730]	[1449,631,628,1360]	8	hSpCas9	negative selection	7218980
48113240	48113263	4	-	27260156	HT29	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.081841688238004	[500]	[514,739,628,439]	-2	hSpCas9	negative selection	7275980
48113230	48113253	4	+	27260156	HT29	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	-0.1415900204624853	[655]	[675,883,608,726]	-3	hSpCas9	negative selection	7275981
48114385	48114408	4	-	27260156	HT29	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.2991738121312011	[1213]	[1878,1962,1945,1516]	6	hSpCas9	negative selection	7275982
48114370	48114393	4	+	27260156	HT29	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	0.002755081667376022	[433]	[516,585,585,436]	0	hSpCas9	negative selection	7340229
48134150	48134173	4	+	27260156	HT29	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.3861454047856331	[783]	[858,702,642,715]	-6	hSpCas9	negative selection	7340230
48113266	48113289	4	+	27260156	HT29	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.3616190753617683	[730]	[1206,1278,1176,937]	7	hSpCas9	negative selection	7340231
48113240	48113263	4	-	27260156	MHHES1	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.13157245323461159	[500]	[568,516,815,555]	2	hSpCas9	negative selection	7397231
48113230	48113253	4	+	27260156	MHHES1	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.16507489395212083	[655]	[924,991,793,652]	3	hSpCas9	negative selection	7397232
48114385	48114408	4	-	27260156	MHHES1	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.3168581539476103	[1213]	[1703,2049,1800,1339]	6	hSpCas9	negative selection	7397233
48114370	48114393	4	+	27260156	MHHES1	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.30801600770501364	[433]	[279,496,396,392]	-5	hSpCas9	negative selection	7461480
48134150	48134173	4	+	27260156	MHHES1	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.2939790254703805	[783]	[1035,726,731,467]	-5	hSpCas9	negative selection	7461481
48113266	48113289	4	+	27260156	MHHES1	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.2656479558969892	[730]	[1069,1102,1198,663]	5	hSpCas9	negative selection	7461482
48113240	48113263	4	-	27260156	MEWO	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.21799467651914062	[500]	[420,474,315]	-5	hSpCas9	negative selection	7518482
48113230	48113253	4	+	27260156	MEWO	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.07041353919214122	[655]	[805,528,629]	1	hSpCas9	negative selection	7518483
48114385	48114408	4	-	27260156	MEWO	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	-0.022855587665776556	[1213]	[1368,944,1088]	0	hSpCas9	negative selection	7518484
48114370	48114393	4	+	27260156	MEWO	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.6622577680291303	[433]	[328,190,263]	-8	hSpCas9	negative selection	7582731
48134150	48134173	4	+	27260156	MEWO	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.5473924148272746	[783]	[588,589,342]	-8	hSpCas9	negative selection	7582732
48113266	48113289	4	+	27260156	MEWO	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.17242026384170794	[730]	[979,671,700]	4	hSpCas9	negative selection	7582733
48113240	48113263	4	-	27260156	LNCAPCLONEFGC	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.15304150353305623	[500]	[552,508,639,334]	2	hSpCas9	negative selection	7639733
48113230	48113253	4	+	27260156	LNCAPCLONEFGC	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.2313882190997979	[655]	[927,653,667,533]	3	hSpCas9	negative selection	7639734
48114385	48114408	4	-	27260156	LNCAPCLONEFGC	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.06847858235068927	[1213]	[1096,1162,1177,1177]	1	hSpCas9	negative selection	7639735
48114370	48114393	4	+	27260156	LNCAPCLONEFGC	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.23532533192368293	[433]	[260,357,296,413]	-4	hSpCas9	negative selection	7703982
48134150	48134173	4	+	27260156	LNCAPCLONEFGC	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.665132709349903	[783]	[418,349,614,438]	-7	hSpCas9	negative selection	7703983
48113266	48113289	4	+	27260156	LNCAPCLONEFGC	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.10257722582794027	[730]	[565,567,685,660]	-2	hSpCas9	negative selection	7703984
48113240	48113263	4	-	27260156	PANC0327	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.1268881460594753	[500]	[609,383,478,493]	1	hSpCas9	negative selection	7760984
48113230	48113253	4	+	27260156	PANC0327	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.4556189420869313	[655]	[551,375,1134,1167]	6	hSpCas9	negative selection	7760985
48114385	48114408	4	-	27260156	PANC0327	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	-0.1687962867304924	[1213]	[1156,800,1088,826]	-3	hSpCas9	negative selection	7760986
48114370	48114393	4	+	27260156	PANC0327	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.4353490685141275	[433]	[249,450,229,184]	-6	hSpCas9	negative selection	7825233
48134150	48134173	4	+	27260156	PANC0327	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	0.0033969020281517937	[783]	[994,412,610,833]	0	hSpCas9	negative selection	7825234
48113266	48113289	4	+	27260156	PANC0327	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.25061226792879554	[730]	[815,833,923,511]	3	hSpCas9	negative selection	7825235
48113240	48113263	4	-	27260156	NCIH2009	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.5755042360845349	[500]	[1168,900,1084]	7	hSpCas9	negative selection	7882235
48113230	48113253	4	+	27260156	NCIH2009	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.36514533687900674	[655]	[1167,1182,1185]	5	hSpCas9	negative selection	7882236
48114385	48114408	4	-	27260156	NCIH2009	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.09616605764028074	[1213]	[2053,1632,1799]	1	hSpCas9	negative selection	7882237
48114370	48114393	4	+	27260156	NCIH2009	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.024377092806350906	[433]	[752,518,547]	0	hSpCas9	negative selection	7946484
48134150	48134173	4	+	27260156	NCIH2009	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.7249454397637085	[783]	[683,565,742]	-7	hSpCas9	negative selection	7946485
48113266	48113289	4	+	27260156	NCIH2009	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.25058368140565174	[730]	[940,653,998]	-3	hSpCas9	negative selection	7946486
48113240	48113263	4	-	27260156	NCIH1373	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.3211264561000057	[500]	[726,336,625,311]	3	hSpCas9	negative selection	8003486
48113230	48113253	4	+	27260156	NCIH1373	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	-0.004114044689415952	[655]	[445,1064,408,248]	0	hSpCas9	negative selection	8003487
48114385	48114408	4	-	27260156	NCIH1373	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	-0.01863285961560024	[1213]	[1144,1338,1367,391]	0	hSpCas9	negative selection	8003488
48114370	48114393	4	+	27260156	NCIH1373	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.8596435504629051	[433]	[278,218,273,80]	-7	hSpCas9	negative selection	8067735
48134150	48134173	4	+	27260156	NCIH1373	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.7004364350382954	[783]	[374,795,432,131]	-6	hSpCas9	negative selection	8067736
48113266	48113289	4	+	27260156	NCIH1373	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.18379060205521808	[730]	[1048,437,563,243]	-2	hSpCas9	negative selection	8067737
48113240	48113263	4	-	27260156	PATU8902	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.4032897407272383	[500]	[1271,957,774,683]	4	hSpCas9	negative selection	8124737
48113230	48113253	4	+	27260156	PATU8902	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.2197291873223396	[655]	[749,1416,1208,807]	2	hSpCas9	negative selection	8124738
48114385	48114408	4	-	27260156	PATU8902	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.5052932114121189	[1213]	[1880,3128,1822,2974]	5	hSpCas9	negative selection	8124739
48114370	48114393	4	+	27260156	PATU8902	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	0.14749764586372305	[433]	[421,435,794,1032]	1	hSpCas9	negative selection	8188986
48134150	48134173	4	+	27260156	PATU8902	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.5360879593083729	[783]	[1070,882,332,833]	-5	hSpCas9	negative selection	8188987
48113266	48113289	4	+	27260156	PATU8902	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.1376042970250504	[730]	[888,1039,650,1221]	-1	hSpCas9	negative selection	8188988
48113240	48113263	4	-	27260156	PANC1	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.14889100573636577	[500]	[511,357,610,406]	2	hSpCas9	negative selection	8245988
48113230	48113253	4	+	27260156	PANC1	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.10582631858638492	[655]	[642,769,516,529]	1	hSpCas9	negative selection	8245989
48114385	48114408	4	-	27260156	PANC1	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.13140267650162119	[1213]	[1037,1146,1481,924]	2	hSpCas9	negative selection	8245990
48114370	48114393	4	+	27260156	PANC1	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.22596568583822008	[433]	[286,431,314,267]	-4	hSpCas9	negative selection	8310237
48134150	48134173	4	+	27260156	PANC1	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.3927207275121224	[783]	[494,619,682,303]	-6	hSpCas9	negative selection	8310238
48113266	48113289	4	+	27260156	PANC1	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.014737916612552526	[730]	[795,750,543,480]	0	hSpCas9	negative selection	8310239
48113240	48113263	4	-	27260156	PANC0813	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.06223580366617605	[500]	[623,869,344,616]	1	hSpCas9	negative selection	8367239
48113230	48113253	4	+	27260156	PANC0813	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.16919881011883808	[655]	[881,750,857,968]	2	hSpCas9	negative selection	8367240
48114385	48114408	4	-	27260156	PANC0813	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.3997905562907531	[1213]	[2363,1592,1995,1628]	6	hSpCas9	negative selection	8367241
48114370	48114393	4	+	27260156	PANC0813	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.10253507562290752	[433]	[553,532,340,476]	-2	hSpCas9	negative selection	8431488
48134150	48134173	4	+	27260156	PANC0813	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.8014649379005484	[783]	[662,479,473,508]	-8	hSpCas9	negative selection	8431489
48113266	48113289	4	+	27260156	PANC0813	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.3752032552941521	[730]	[1148,1071,1047,1182]	6	hSpCas9	negative selection	8431490
48113240	48113263	4	-	27260156	RDES	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.0707303102519256	[500]	[585,524,674,632]	1	hSpCas9	negative selection	8488490
48113230	48113253	4	+	27260156	RDES	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.272716261508535	[655]	[851,978,748,1056]	4	hSpCas9	negative selection	8488491
48114385	48114408	4	-	27260156	RDES	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.12099098608622594	[1213]	[1117,1564,1542,1951]	2	hSpCas9	negative selection	8488492
48114370	48114393	4	+	27260156	RDES	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.30936188115440927	[433]	[352,420,343,501]	-5	hSpCas9	negative selection	8552739
48134150	48134173	4	+	27260156	RDES	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.6997880765262104	[783]	[476,366,771,644]	-8	hSpCas9	negative selection	8552740
48113266	48113289	4	+	27260156	RDES	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.3043908008377202	[730]	[742,1018,1162,1309]	5	hSpCas9	negative selection	8552741
48113240	48113263	4	-	27260156	PC3	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.05722665007277067	[500]	[275,526,789,490]	-1	hSpCas9	negative selection	8609741
48113230	48113253	4	+	27260156	PC3	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.12912796080445021	[655]	[377,792,1339,673]	3	hSpCas9	negative selection	8609742
48114385	48114408	4	-	27260156	PC3	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.31434101102129985	[1213]	[880,1492,2618,1599]	6	hSpCas9	negative selection	8609743
48114370	48114393	4	+	27260156	PC3	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.11650782036926403	[433]	[247,383,695,412]	-3	hSpCas9	negative selection	8673990
48134150	48134173	4	+	27260156	PC3	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.4522016323474145	[783]	[343,478,865,770]	-8	hSpCas9	negative selection	8673991
48113266	48113289	4	+	27260156	PC3	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.10004011980076255	[730]	[470,725,1508,766]	2	hSpCas9	negative selection	8673992
48113240	48113263	4	-	27260156	PATU8988T	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.2366831159787458	[500]	[197,540,418,504]	-4	hSpCas9	negative selection	8730992
48113230	48113253	4	+	27260156	PATU8988T	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.0056819975333674	[655]	[471,666,491,943]	0	hSpCas9	negative selection	8730993
48114385	48114408	4	-	27260156	PATU8988T	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.5369379724921131	[1213]	[1700,1647,1897,1539]	8	hSpCas9	negative selection	8730994
48114370	48114393	4	+	27260156	PATU8988T	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.05389924569965761	[433]	[281,451,503,378]	-1	hSpCas9	negative selection	8795241
48134150	48134173	4	+	27260156	PATU8988T	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.15723273764901569	[783]	[641,892,499,706]	-3	hSpCas9	negative selection	8795242
48113266	48113289	4	+	27260156	PATU8988T	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.4269803657090795	[730]	[699,914,1004,1193]	7	hSpCas9	negative selection	8795243
48113240	48113263	4	-	27260156	T47D	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.011042010158959933	[500]	[724,475,592,567]	0	hSpCas9	negative selection	8852243
48113230	48113253	4	+	27260156	T47D	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.09533014058339695	[655]	[774,816,766,909]	2	hSpCas9	negative selection	8852244
48114385	48114408	4	-	27260156	T47D	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.30020862095419765	[1213]	[1831,1529,1773,1850]	6	hSpCas9	negative selection	8852245
48114370	48114393	4	+	27260156	T47D	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.11508608731737675	[433]	[504,384,530,451]	-3	hSpCas9	negative selection	8916492
48134150	48134173	4	+	27260156	T47D	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.1688480752166468	[783]	[819,644,933,864]	-4	hSpCas9	negative selection	8916493
48113266	48113289	4	+	27260156	T47D	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.312019306162026	[730]	[1188,819,1156,1082]	6	hSpCas9	negative selection	8916494
48113240	48113263	4	-	27260156	SU8686	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.40938277699085235	[500]	[615,532,706,827]	7	hSpCas9	negative selection	8973494
48113230	48113253	4	+	27260156	SU8686	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.49809151420811326	[655]	[1078,796,802,994]	8	hSpCas9	negative selection	8973495
48114385	48114408	4	-	27260156	SU8686	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.0597930536529343	[1213]	[1182,1190,1171,1519]	1	hSpCas9	negative selection	8973496
48114370	48114393	4	+	27260156	SU8686	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.007675121305982052	[433]	[397,430,539,329]	0	hSpCas9	negative selection	9037743
48134150	48134173	4	+	27260156	SU8686	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.5493583939522668	[783]	[481,551,547,543]	-7	hSpCas9	negative selection	9037744
48113266	48113289	4	+	27260156	SU8686	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.048337758001053666	[730]	[573,728,720,801]	-1	hSpCas9	negative selection	9037745
48113240	48113263	4	-	27260156	SKES1	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.027530757131198957	[500]	[549,684,415,419]	0	hSpCas9	negative selection	9094745
48113230	48113253	4	+	27260156	SKES1	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	-0.0577673677611496	[655]	[820,727,505,507]	-1	hSpCas9	negative selection	9094746
48114385	48114408	4	-	27260156	SKES1	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.07780300560110565	[1213]	[1556,1355,1280,987]	1	hSpCas9	negative selection	9094747
48114370	48114393	4	+	27260156	SKES1	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.2259955841615146	[433]	[348,386,371,367]	-5	hSpCas9	negative selection	9158994
48134150	48134173	4	+	27260156	SKES1	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.46146656654830054	[783]	[629,719,498,457]	-7	hSpCas9	negative selection	9158995
48113266	48113289	4	+	27260156	SKES1	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.4316831249835279	[730]	[1080,1017,1057,804]	8	hSpCas9	negative selection	9158996
48113240	48113263	4	-	27260156	TOV112D	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.14347719117783278	[500]	[420,545,482,387]	-3	hSpCas9	negative selection	9215996
48113230	48113253	4	+	27260156	TOV112D	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	0.11851174434201073	[655]	[708,878,615,688]	2	hSpCas9	negative selection	9215997
48114385	48114408	4	-	27260156	TOV112D	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.1475501612449024	[1213]	[1300,1609,1298,1238]	3	hSpCas9	negative selection	9215998
48114370	48114393	4	+	27260156	TOV112D	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.38778882471373427	[433]	[562,291,227,256]	-6	hSpCas9	negative selection	9280245
48134150	48134173	4	+	27260156	TOV112D	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.16004237960979262	[783]	[787,439,987,540]	-3	hSpCas9	negative selection	9280246
48113266	48113289	4	+	27260156	TOV112D	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.3681497653984823	[730]	[1106,1102,1044,585]	7	hSpCas9	negative selection	9280247
48113240	48113263	4	-	27260156	TC71	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	-0.11105607393653524	[500]	[473,439,534,541]	-3	hSpCas9	negative selection	9337247
48113230	48113253	4	+	27260156	TC71	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	-0.04541601788568744	[655]	[742,683,679,612]	-1	hSpCas9	negative selection	9337248
48114385	48114408	4	-	27260156	TC71	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.14408989675783657	[1213]	[1455,1584,1255,1461]	3	hSpCas9	negative selection	9337249
48114370	48114393	4	+	27260156	TC71	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.48176995783279347	[433]	[280,388,268,400]	-8	hSpCas9	negative selection	9401496
48134150	48134173	4	+	27260156	TC71	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.19121904901248377	[783]	[814,580,679,876]	-5	hSpCas9	negative selection	9401497
48113266	48113289	4	+	27260156	TC71	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.24305189776363534	[730]	[939,795,965,1010]	6	hSpCas9	negative selection	9401498
48113240	48113263	4	-	27260156	TC32	viability	AAAAATACACCCAGCGTCGCAGG	TXK	ENSG00000074966	0.18877728844875885	[500]	[455,462,591,656]	3	hSpCas9	negative selection	9458498
48113230	48113253	4	+	27260156	TC32	viability	TGAGCCACGGCCTGCGACGCTGG	TXK	ENSG00000074966	-0.0010352877633976187	[655]	[629,381,867,682]	0	hSpCas9	negative selection	9458499
48114385	48114408	4	-	27260156	TC32	viability	TTCAGATAACACCATCCAGTCGG	TXK	ENSG00000074966	0.0028421853665792085	[1213]	[1200,779,1478,1237]	0	hSpCas9	negative selection	9458500
48114370	48114393	4	+	27260156	TC32	viability	AGCAGCAACAGAAAACCGACTGG	TXK	ENSG00000074966	-0.1720920603418955	[433]	[275,370,387,403]	-3	hSpCas9	negative selection	9522747
48134150	48134173	4	+	27260156	TC32	viability	CTCACAGGAGGAAAGGATCATGG	TXK	ENSG00000074966	-0.7325891208675464	[783]	[295,381,540,595]	-9	hSpCas9	negative selection	9522748
48113266	48113289	4	+	27260156	TC32	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.1276925539308731	[730]	[574,500,877,620]	-2	hSpCas9	negative selection	9522749
48067622	48067645	4	+	27869803	HPAFII	viability after 27 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.21289178049633195	[73]	[25,60,NaN]	1	hSpCas9	negative selection	9588326
48071561	48071584	4	-	27869803	HPAFII	viability after 27 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	0.10178518319525176	[169]	[96,94,NaN]	0	hSpCas9	negative selection	9588327
48076458	48076481	4	-	27869803	HPAFII	viability after 27 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	-0.07486548298477924	[160]	[87,73,NaN]	0	hSpCas9	negative selection	9588328
48080013	48080036	4	+	27869803	HPAFII	viability after 27 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.00179700464282731	[240]	[131,121,NaN]	0	hSpCas9	negative selection	9588329
48089761	48089784	4	-	27869803	HPAFII	viability after 27 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	-0.160535042412068	[200]	[117,74,NaN]	-1	hSpCas9	negative selection	9588330
48134138	48134161	4	+	27869803	HPAFII	viability after 27 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	-0.43954705994175525	[279]	[191,38,NaN]	-3	hSpCas9	negative selection	9588331
48067622	48067645	4	+	27869803	HPAFII	viability after 15 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.8633313925726394	[73]	[148,141,NaN]	8	hSpCas9	negative selection	9670775
48071561	48071584	4	-	27869803	HPAFII	viability after 15 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	-0.15457036971028526	[169]	[247,111,NaN]	-2	hSpCas9	negative selection	9670776
48076458	48076481	4	-	27869803	HPAFII	viability after 15 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.18048177213237976	[160]	[266,151,NaN]	2	hSpCas9	negative selection	9670777
48080013	48080036	4	+	27869803	HPAFII	viability after 15 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	0.3580376096802467	[240]	[347,321,NaN]	4	hSpCas9	negative selection	9670778
48089761	48089784	4	-	27869803	HPAFII	viability after 15 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.24618823897432363	[200]	[418,154,NaN]	3	hSpCas9	negative selection	9670779
48134138	48134161	4	+	27869803	HPAFII	viability after 15 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	0.05149119798296323	[279]	[576,146,NaN]	0	hSpCas9	negative selection	9670780
48067622	48067645	4	+	27869803	ASPC1	viability after 36 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	1.157982162539887	[230]	[267,275,39]	9	hSpCas9	negative selection	9753224
48071561	48071584	4	-	27869803	ASPC1	viability after 36 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	0.5461873201390948	[418]	[275,246,140]	5	hSpCas9	negative selection	9753225
48076458	48076481	4	-	27869803	ASPC1	viability after 36 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.9673541913769886	[370]	[257,289,217]	8	hSpCas9	negative selection	9753226
48080013	48080036	4	+	27869803	ASPC1	viability after 36 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.6408874361271208	[646]	[122,190,121]	-6	hSpCas9	negative selection	9753227
48089761	48089784	4	-	27869803	ASPC1	viability after 36 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.43772381997741744	[626]	[168,343,344]	4	hSpCas9	negative selection	9753228
48134138	48134161	4	+	27869803	ASPC1	viability after 36 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	-0.12102167494073464	[688]	[209,124,302]	-1	hSpCas9	negative selection	9753229
48067622	48067645	4	+	27869803	PATU8988S	viability after 35 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.5763279529332622	[252]	[121,181,NaN]	6	hSpCas9	negative selection	9835673
48071561	48071584	4	-	27869803	PATU8988S	viability after 35 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	0.9294900156173463	[328]	[194,309,NaN]	8	hSpCas9	negative selection	9835674
48076458	48076481	4	-	27869803	PATU8988S	viability after 35 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.0544169977940544	[269]	[78,146,NaN]	0	hSpCas9	negative selection	9835675
48080013	48080036	4	+	27869803	PATU8988S	viability after 35 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.280143640987296	[409]	[128,142,NaN]	-3	hSpCas9	negative selection	9835676
48089761	48089784	4	-	27869803	PATU8988S	viability after 35 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	-0.2978770196089304	[413]	[193,76,NaN]	-3	hSpCas9	negative selection	9835677
48134138	48134161	4	+	27869803	PATU8988S	viability after 35 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	-1.1020987320526063	[670]	[77,173,NaN]	-8	hSpCas9	negative selection	9835678
48067622	48067645	4	+	27869803	PATU8988S	viability after 31 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.28361905491610073	[252]	[113,133,NaN]	3	hSpCas9	negative selection	9918122
48071561	48071584	4	-	27869803	PATU8988S	viability after 31 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	0.8844271851757461	[328]	[118,398,NaN]	8	hSpCas9	negative selection	9918123
48076458	48076481	4	-	27869803	PATU8988S	viability after 31 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	-0.04717461337331352	[269]	[90,120,NaN]	0	hSpCas9	negative selection	9918124
48080013	48080036	4	+	27869803	PATU8988S	viability after 31 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	-0.44326265830768313	[409]	[110,131,NaN]	-5	hSpCas9	negative selection	9918125
48089761	48089784	4	-	27869803	PATU8988S	viability after 31 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.020147677076140902	[413]	[173,158,NaN]	0	hSpCas9	negative selection	9918126
48134138	48134161	4	+	27869803	PATU8988S	viability after 31 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	-0.7891611723925998	[670]	[105,216,NaN]	-7	hSpCas9	negative selection	9918127
48067622	48067645	4	+	27869803	HPAFII	viability after 35 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.096130577402048	[73]	[8,74,NaN]	0	hSpCas9	negative selection	10000571
48071561	48071584	4	-	27869803	HPAFII	viability after 35 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	0.10731192254800687	[169]	[95,88,NaN]	0	hSpCas9	negative selection	10000572
48076458	48076481	4	-	27869803	HPAFII	viability after 35 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	-0.5326414809869371	[160]	[37,76,NaN]	-3	hSpCas9	negative selection	10000573
48080013	48080036	4	+	27869803	HPAFII	viability after 35 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	0.3142351429040752	[240]	[130,174,NaN]	2	hSpCas9	negative selection	10000574
48089761	48089784	4	-	27869803	HPAFII	viability after 35 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.5560870824977147	[200]	[190,102,NaN]	3	hSpCas9	negative selection	10000575
48134138	48134161	4	+	27869803	HPAFII	viability after 35 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	0.01852685453050057	[279]	[247,25,NaN]	0	hSpCas9	negative selection	10000576
48067622	48067645	4	+	27869803	HPAFII	viability after 31 days	GCATTCTGTTTCCGGTCACCAGG	TXK	ENSG00000074966	0.05233783113910895	[73]	[10,77,NaN]	0	hSpCas9	negative selection	10083020
48071561	48071584	4	-	27869803	HPAFII	viability after 31 days	CAGGCTATATCGCCCTCACCTGG	TXK	ENSG00000074966	0.544773557648989	[169]	[131,146,NaN]	4	hSpCas9	negative selection	10083021
48076458	48076481	4	-	27869803	HPAFII	viability after 31 days	TCTTCTTTCCATAGGCGGCAAGG	TXK	ENSG00000074966	0.33099886544941814	[160]	[105,121,NaN]	2	hSpCas9	negative selection	10083022
48080013	48080036	4	+	27869803	HPAFII	viability after 31 days	TCTCCCTGAGATAGTTAAGCAGG	TXK	ENSG00000074966	0.1916113587991413	[240]	[108,203,NaN]	1	hSpCas9	negative selection	10083023
48089761	48089784	4	-	27869803	HPAFII	viability after 31 days	AGTTGTTTACCAGCCACAGCTGG	TXK	ENSG00000074966	0.4665322027281356	[200]	[219,85,NaN]	3	hSpCas9	negative selection	10083024
48134138	48134161	4	+	27869803	HPAFII	viability after 31 days	AAGCCCATCTTACTCACAGGAGG	TXK	ENSG00000074966	0.25873184700803364	[279]	[310,53,NaN]	1	hSpCas9	negative selection	10083025
48094092	48094115	4	+	28162770	P31FUJ	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.2824295829170665	[218]	[312]	3	hSpCas9	negative selection	10259605
48112445	48112468	4	+	28162770	P31FUJ	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	0.9598428735280171	[62]	[143]	9	hSpCas9	negative selection	10259606
48079955	48079978	4	-	28162770	P31FUJ	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.7833036180975996	[578]	[1170]	8	hSpCas9	negative selection	10259607
48112327	48112350	4	-	28162770	P31FUJ	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	0.3861076282301152	[167]	[257]	4	hSpCas9	negative selection	10259608
48089748	48089771	4	+	28162770	P31FUJ	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	-0.2724859058868608	[257]	[250]	-3	hSpCas9	negative selection	10259609
48073996	48074019	4	-	28162770	P31FUJ	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	0.3825339453502963	[93]	[143]	4	hSpCas9	negative selection	10259610
48114374	48114397	4	+	28162770	P31FUJ	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	0.35021202451725575	[246]	[369]	4	hSpCas9	negative selection	10259611
48114347	48114370	4	-	28162770	P31FUJ	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	0.20947187913826743	[222]	[302]	2	hSpCas9	negative selection	10259612
48113266	48113289	4	+	28162770	P31FUJ	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.22431501810695242	[396]	[544]	2	hSpCas9	negative selection	10259613
48113234	48113257	4	-	28162770	P31FUJ	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	0.6428696605834197	[108]	[199]	7	hSpCas9	negative selection	10259614
48094092	48094115	4	+	28162770	TF1	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	NaN	[NaN]	[225]	1	hSpCas9	negative selection	10428971
48112445	48112468	4	+	28162770	TF1	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10428972
48079955	48079978	4	-	28162770	TF1	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	NaN	[NaN]	[468]	1	hSpCas9	negative selection	10428973
48112327	48112350	4	-	28162770	TF1	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10428974
48089748	48089771	4	+	28162770	TF1	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	NaN	[NaN]	[260]	1	hSpCas9	negative selection	10428975
48073996	48074019	4	-	28162770	TF1	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10428976
48114374	48114397	4	+	28162770	TF1	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	NaN	[NaN]	[424]	1	hSpCas9	negative selection	10428977
48114347	48114370	4	-	28162770	TF1	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	NaN	[NaN]	[176]	1	hSpCas9	negative selection	10428978
48113266	48113289	4	+	28162770	TF1	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	NaN	[NaN]	[306]	1	hSpCas9	negative selection	10428979
48113234	48113257	4	-	28162770	TF1	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	NaN	[NaN]	[190]	1	hSpCas9	negative selection	10428980
48094092	48094115	4	+	28162770	SKM1	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.22862437504796257	[69]	[144]	2	hSpCas9	negative selection	10598337
48112445	48112468	4	+	28162770	SKM1	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	-0.08503610385579963	[8]	[14]	0	hSpCas9	negative selection	10598338
48079955	48079978	4	-	28162770	SKM1	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	1.3049895074149713	[143]	[628]	9	hSpCas9	negative selection	10598339
48112327	48112350	4	-	28162770	SKM1	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	0.7409344963691518	[43]	[129]	7	hSpCas9	negative selection	10598340
48089748	48089771	4	+	28162770	SKM1	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.6008553057161374	[68]	[184]	6	hSpCas9	negative selection	10598341
48073996	48074019	4	-	28162770	SKM1	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	-0.2640062449011187	[35]	[52]	-2	hSpCas9	negative selection	10598342
48114374	48114397	4	+	28162770	SKM1	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	0.4285417636285914	[57]	[137]	4	hSpCas9	negative selection	10598343
48114347	48114370	4	-	28162770	SKM1	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	-0.5499221525852045	[52]	[63]	-4	hSpCas9	negative selection	10598344
48113266	48113289	4	+	28162770	SKM1	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.020781562136503173	[100]	[175]	0	hSpCas9	negative selection	10598345
48113234	48113257	4	-	28162770	SKM1	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	1.2286243750479626	[20]	[86]	9	hSpCas9	negative selection	10598346
48094092	48094115	4	+	28162770	SKM1	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.22862437504796257	[69]	[144]	2	hSpCas9	negative selection	10767703
48112445	48112468	4	+	28162770	SKM1	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	-0.08503610385579963	[8]	[14]	0	hSpCas9	negative selection	10767704
48079955	48079978	4	-	28162770	SKM1	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	1.3049895074149713	[143]	[628]	9	hSpCas9	negative selection	10767705
48112327	48112350	4	-	28162770	SKM1	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	0.7409344963691518	[43]	[129]	7	hSpCas9	negative selection	10767706
48089748	48089771	4	+	28162770	SKM1	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.6008553057161374	[68]	[184]	6	hSpCas9	negative selection	10767707
48073996	48074019	4	-	28162770	SKM1	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	-0.2640062449011187	[35]	[52]	-2	hSpCas9	negative selection	10767708
48114374	48114397	4	+	28162770	SKM1	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	0.4285417636285914	[57]	[137]	4	hSpCas9	negative selection	10767709
48114347	48114370	4	-	28162770	SKM1	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	-0.5499221525852045	[52]	[63]	-4	hSpCas9	negative selection	10767710
48113266	48113289	4	+	28162770	SKM1	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.020781562136503173	[100]	[175]	0	hSpCas9	negative selection	10767711
48113234	48113257	4	-	28162770	SKM1	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	1.2286243750479626	[20]	[86]	9	hSpCas9	negative selection	10767712
48094092	48094115	4	+	28162770	PL21	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.11432024602831625	[328]	[154]	1	hSpCas9	negative selection	10937069
48112445	48112468	4	+	28162770	PL21	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	-1.095316269036851	[53]	[10]	-6	hSpCas9	negative selection	10937070
48079955	48079978	4	-	28162770	PL21	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.586730426241123	[588]	[384]	5	hSpCas9	negative selection	10937071
48112327	48112350	4	-	28162770	PL21	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	0.5433443690070973	[174]	[110]	5	hSpCas9	negative selection	10937072
48089748	48089771	4	+	28162770	PL21	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.3694595855009202	[264]	[148]	3	hSpCas9	negative selection	10937073
48073996	48074019	4	-	28162770	PL21	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	-0.9697853869529922	[71]	[15]	-6	hSpCas9	negative selection	10937074
48114374	48114397	4	+	28162770	PL21	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	-0.40050450846410574	[184]	[60]	-3	hSpCas9	negative selection	10937075
48114347	48114370	4	-	28162770	PL21	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	0.509243669019099	[112]	[69]	4	hSpCas9	negative selection	10937076
48113266	48113289	4	+	28162770	PL21	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.3128692143500894	[282]	[152]	2	hSpCas9	negative selection	10937077
48113234	48113257	4	-	28162770	PL21	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	0.4683357254388927	[92]	[55]	4	hSpCas9	negative selection	10937078
48094092	48094115	4	+	28162770	P31FUJ	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.2824295829170665	[218]	[312]	3	hSpCas9	negative selection	11106435
48112445	48112468	4	+	28162770	P31FUJ	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	0.9598428735280171	[62]	[143]	9	hSpCas9	negative selection	11106436
48079955	48079978	4	-	28162770	P31FUJ	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.7833036180975996	[578]	[1170]	8	hSpCas9	negative selection	11106437
48112327	48112350	4	-	28162770	P31FUJ	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	0.3861076282301152	[167]	[257]	4	hSpCas9	negative selection	11106438
48089748	48089771	4	+	28162770	P31FUJ	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	-0.2724859058868608	[257]	[250]	-3	hSpCas9	negative selection	11106439
48073996	48074019	4	-	28162770	P31FUJ	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	0.3825339453502963	[93]	[143]	4	hSpCas9	negative selection	11106440
48114374	48114397	4	+	28162770	P31FUJ	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	0.35021202451725575	[246]	[369]	4	hSpCas9	negative selection	11106441
48114347	48114370	4	-	28162770	P31FUJ	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	0.20947187913826743	[222]	[302]	2	hSpCas9	negative selection	11106442
48113266	48113289	4	+	28162770	P31FUJ	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.22431501810695242	[396]	[544]	2	hSpCas9	negative selection	11106443
48113234	48113257	4	-	28162770	P31FUJ	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	0.6428696605834197	[108]	[199]	7	hSpCas9	negative selection	11106444
48094092	48094115	4	+	28162770	OCIAML5	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.05037811971332953	[129]	[242]	0	hSpCas9	negative selection	11275801
48112445	48112468	4	+	28162770	OCIAML5	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	1.9660951061501901	[18]	[133]	9	hSpCas9	negative selection	11275802
48079955	48079978	4	-	28162770	OCIAML5	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.537409222000816	[362]	[950]	5	hSpCas9	negative selection	11275803
48112327	48112350	4	-	28162770	OCIAML5	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	1.1064413002175395	[96]	[376]	8	hSpCas9	negative selection	11275804
48089748	48089771	4	+	28162770	OCIAML5	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	-0.11954688172898291	[129]	[215]	-1	hSpCas9	negative selection	11275805
48073996	48074019	4	-	28162770	OCIAML5	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	0.4333356479982514	[79]	[194]	4	hSpCas9	negative selection	11275806
48114374	48114397	4	+	28162770	OCIAML5	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	1.5517561409189204	[112]	[597]	9	hSpCas9	negative selection	11275807
48114347	48114370	4	-	28162770	OCIAML5	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	-1.2071615296865588	[109]	[85]	-6	hSpCas9	negative selection	11275808
48113266	48113289	4	+	28162770	OCIAML5	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.6150594395633011	[237]	[657]	5	hSpCas9	negative selection	11275809
48113234	48113257	4	-	28162770	OCIAML5	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	-1.3037625407216888	[92]	[67]	-6	hSpCas9	negative selection	11275810
48094092	48094115	4	+	28162770	EOL1	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.2728942147624299	[486]	[309]	2	hSpCas9	negative selection	11445167
48112445	48112468	4	+	28162770	EOL1	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	-0.053425922099466394	[64]	[32]	0	hSpCas9	negative selection	11445168
48079955	48079978	4	-	28162770	EOL1	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.5685264780147643	[941]	[735]	5	hSpCas9	negative selection	11445169
48112327	48112350	4	-	28162770	EOL1	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	-0.7758919465705577	[324]	[99]	-5	hSpCas9	negative selection	11445170
48089748	48089771	4	+	28162770	EOL1	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	-0.7022349048452485	[419]	[135]	-5	hSpCas9	negative selection	11445171
48073996	48074019	4	-	28162770	EOL1	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	-0.08272022889350472	[198]	[98]	0	hSpCas9	negative selection	11445172
48114374	48114397	4	+	28162770	EOL1	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	0.39269660730894085	[239]	[165]	3	hSpCas9	negative selection	11445173
48114347	48114370	4	-	28162770	EOL1	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	-0.5802443804666382	[209]	[73]	-4	hSpCas9	negative selection	11445174
48113266	48113289	4	+	28162770	EOL1	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.34173229376691344	[355]	[147]	-3	hSpCas9	negative selection	11445175
48113234	48113257	4	-	28162770	EOL1	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	-0.4539638516831954	[90]	[34]	-3	hSpCas9	negative selection	11445176
48094092	48094115	4	+	28162770	MOLM13	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	1.0044888607043359	[363]	[527]	7	hSpCas9	negative selection	11614533
48112445	48112468	4	+	28162770	MOLM13	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	0.09174089565932997	[60]	[46]	0	hSpCas9	negative selection	11614534
48079955	48079978	4	-	28162770	MOLM13	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	1.1115857070562016	[721]	[1127]	8	hSpCas9	negative selection	11614535
48112327	48112350	4	-	28162770	MOLM13	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	0.36141275341526824	[252]	[234]	2	hSpCas9	negative selection	11614536
48089748	48089771	4	+	28162770	MOLM13	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.20171526818021768	[367]	[305]	1	hSpCas9	negative selection	11614537
48073996	48074019	4	-	28162770	MOLM13	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	1.0877856723751222	[135]	[208]	8	hSpCas9	negative selection	11614538
48114374	48114397	4	+	28162770	MOLM13	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	-0.09504681284657865	[324]	[219]	0	hSpCas9	negative selection	11614539
48114347	48114370	4	-	28162770	MOLM13	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	-0.9071500498023458	[165]	[63]	-5	hSpCas9	negative selection	11614540
48113266	48113289	4	+	28162770	MOLM13	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.2063041923478548	[397]	[331]	1	hSpCas9	negative selection	11614541
48113234	48113257	4	-	28162770	MOLM13	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	1.6719809861380828	[101]	[234]	9	hSpCas9	negative selection	11614542
48094092	48094115	4	+	28162770	HEL	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.5924337501522915	[320]	[309]	5	hSpCas9	negative selection	11783899
48112445	48112468	4	+	28162770	HEL	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	-0.6150589254672898	[54]	[22]	-4	hSpCas9	negative selection	11783900
48079955	48079978	4	-	28162770	HEL	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.2571520998906769	[694]	[531]	2	hSpCas9	negative selection	11783901
48112327	48112350	4	-	28162770	HEL	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	-0.32555230827230486	[224]	[114]	-2	hSpCas9	negative selection	11783902
48089748	48089771	4	+	28162770	HEL	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.11318945159780736	[331]	[229]	0	hSpCas9	negative selection	11783903
48073996	48074019	4	-	28162770	HEL	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	0.8952808640165084	[114]	[136]	7	hSpCas9	negative selection	11783904
48114374	48114397	4	+	28162770	HEL	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	1.2549228014565377	[279]	[427]	9	hSpCas9	negative selection	11783905
48114347	48114370	4	-	28162770	HEL	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	0.14154468897179862	[183]	[129]	1	hSpCas9	negative selection	11783906
48113266	48113289	4	+	28162770	HEL	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.5357787799580078	[420]	[185]	-4	hSpCas9	negative selection	11783907
48113234	48113257	4	-	28162770	HEL	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	-0.7606168622308513	[81]	[30]	-5	hSpCas9	negative selection	11783908
48094092	48094115	4	+	28162770	MV411	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.03857212038204899	[229]	[198]	0	hSpCas9	negative selection	11953265
48112445	48112468	4	+	28162770	MV411	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	0.5347195028632465	[58]	[71]	5	hSpCas9	negative selection	11953266
48079955	48079978	4	-	28162770	MV411	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.7772954520634772	[506]	[731]	7	hSpCas9	negative selection	11953267
48112327	48112350	4	-	28162770	MV411	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	-0.23318829012364525	[179]	[128]	-2	hSpCas9	negative selection	11953268
48089748	48089771	4	+	28162770	MV411	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	-0.6464340983558816	[261]	[140]	-4	hSpCas9	negative selection	11953269
48073996	48074019	4	-	28162770	MV411	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	0.07998080493121273	[72]	[64]	0	hSpCas9	negative selection	11953270
48114374	48114397	4	+	28162770	MV411	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	0.7638357650208599	[157]	[225]	7	hSpCas9	negative selection	11953271
48114347	48114370	4	-	28162770	MV411	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	0.3429178596370037	[189]	[202]	3	hSpCas9	negative selection	11953272
48113266	48113289	4	+	28162770	MV411	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	0.3434393706601292	[217]	[232]	3	hSpCas9	negative selection	11953273
48113234	48113257	4	-	28162770	MV411	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	0.971803108169348	[68]	[113]	8	hSpCas9	negative selection	11953274
48094092	48094115	4	+	28162770	MONOMAC1	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	-0.20760608876974102	[136]	[135]	-2	hSpCas9	negative selection	12122631
48112445	48112468	4	+	28162770	MONOMAC1	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	-1.1230362656157769	[37]	[19]	-7	hSpCas9	negative selection	12122632
48079955	48079978	4	-	28162770	MONOMAC1	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	1.1140407277590292	[346]	[860]	8	hSpCas9	negative selection	12122633
48112327	48112350	4	-	28162770	MONOMAC1	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	0.7793118848758009	[122]	[241]	7	hSpCas9	negative selection	12122634
48089748	48089771	4	+	28162770	MONOMAC1	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.6924047777927479	[121]	[225]	6	hSpCas9	negative selection	12122635
48073996	48074019	4	-	28162770	MONOMAC1	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	0.16861262525712672	[51]	[66]	1	hSpCas9	negative selection	12122636
48114374	48114397	4	+	28162770	MONOMAC1	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	0.051990700780360694	[137]	[163]	0	hSpCas9	negative selection	12122637
48114347	48114370	4	-	28162770	MONOMAC1	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	-0.5811803383926137	[76]	[58]	-5	hSpCas9	negative selection	12122638
48113266	48113289	4	+	28162770	MONOMAC1	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.6791885421969345	[175]	[125]	-5	hSpCas9	negative selection	12122639
48113234	48113257	4	-	28162770	MONOMAC1	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	0.4968600252147665	[67]	[109]	5	hSpCas9	negative selection	12122640
48094092	48094115	4	+	28162770	OCIAML2	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.8139118537550922	[42]	[418]	7	hSpCas9	negative selection	12291997
48112445	48112468	4	+	28162770	OCIAML2	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	-0.19761133083574522	[5]	[28]	-2	hSpCas9	negative selection	12291998
48079955	48079978	4	-	28162770	OCIAML2	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.9374549133949157	[90]	[965]	8	hSpCas9	negative selection	12291999
48112327	48112350	4	-	28162770	OCIAML2	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	-0.45073026780445646	[53]	[218]	-4	hSpCas9	negative selection	12292000
48089748	48089771	4	+	28162770	OCIAML2	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	0.8723598851730306	[33]	[344]	8	hSpCas9	negative selection	12292001
48073996	48074019	4	-	28162770	OCIAML2	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	0.4553695933140621	[14]	[113]	4	hSpCas9	negative selection	12292002
48114374	48114397	4	+	28162770	OCIAML2	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	0.6362853786743505	[25]	[223]	6	hSpCas9	negative selection	12292003
48114347	48114370	4	-	28162770	OCIAML2	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	0.5293701747578388	[26]	[215]	5	hSpCas9	negative selection	12292004
48113266	48113289	4	+	28162770	OCIAML2	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.33312630149222633	[64]	[285]	-3	hSpCas9	negative selection	12292005
48113234	48113257	4	-	28162770	OCIAML2	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	0.19922157306550803	[10]	[69]	2	hSpCas9	negative selection	12292006
48094092	48094115	4	+	28162770	OCIAML3	viability	GGTGATACCAGATTAACTCAGGG	TXK	ENSG00000074966	0.308695158320922	[68]	[257]	3	hSpCas9	negative selection	12461363
48112445	48112468	4	+	28162770	OCIAML3	viability	GCAACCTCAGAGGGTGGGAGGGG	TXK	ENSG00000074966	-2.0634929236253834	[17]	[12]	-8	hSpCas9	negative selection	12461364
48079955	48079978	4	-	28162770	OCIAML3	viability	GTATGCCAGGATATATGTGAAGG	TXK	ENSG00000074966	0.5980401720162893	[150]	[689]	5	hSpCas9	negative selection	12461365
48112327	48112350	4	-	28162770	OCIAML3	viability	AGAAATACAATCCTCACTGGTGG	TXK	ENSG00000074966	0.05089740085327511	[54]	[171]	0	hSpCas9	negative selection	12461366
48089748	48089771	4	+	28162770	OCIAML3	viability	ACCGTAGCTAAACCCAGCTGTGG	TXK	ENSG00000074966	1.33199177823206	[59]	[455]	9	hSpCas9	negative selection	12461367
48073996	48074019	4	-	28162770	OCIAML3	viability	GAGCCAAGTTCCCAATCAAGTGG	TXK	ENSG00000074966	1.6154457253047867	[11]	[110]	9	hSpCas9	negative selection	12461368
48114374	48114397	4	+	28162770	OCIAML3	viability	GCAACAGAAAACCGACTGGATGG	TXK	ENSG00000074966	0.16417443975173862	[80]	[273]	1	hSpCas9	negative selection	12461369
48114347	48114370	4	-	28162770	OCIAML3	viability	GTTGCTGTTCAGTGCAGAAGCGG	TXK	ENSG00000074966	0.2133472817334409	[51]	[181]	2	hSpCas9	negative selection	12461370
48113266	48113289	4	+	28162770	OCIAML3	viability	GAAGCTCTTCATCTGTGCTCAGG	TXK	ENSG00000074966	-0.33348009010094415	[95]	[229]	-3	hSpCas9	negative selection	12461371
48113234	48113257	4	-	28162770	OCIAML3	viability	ACACCCAGCGTCGCAGGCCGTGG	TXK	ENSG00000074966	0.9332393625407058	[16]	[97]	7	hSpCas9	negative selection	12461372