Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7297
• Symbol: TYK2
• Description: tyrosine kinase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/TYK2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
10365547	10365570	19	-	26472758	Jiyoye	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	0.44440828770484875	[152]	[156]	3	hSpCas9	negative selection	175785
10356577	10356600	19	+	26472758	Jiyoye	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	-1.0657605014811715	[160]	[57]	-6	hSpCas9	negative selection	175786
10378261	10378284	19	+	26472758	Jiyoye	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	0.33813373707622213	[106]	[101]	2	hSpCas9	negative selection	175787
10366475	10366498	19	+	26472758	Jiyoye	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-0.2741421831104184	[177]	[110]	-2	hSpCas9	negative selection	175788
10365534	10365557	19	-	26472758	Jiyoye	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	0.4416637578911639	[123]	[126]	3	hSpCas9	negative selection	175789
10364715	10364738	19	+	26472758	Jiyoye	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.23328223180698626	[52]	[33]	-2	hSpCas9	negative selection	175790
10364638	10364661	19	+	26472758	Jiyoye	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	1.0701403942283028	[11]	[18]	7	hSpCas9	negative selection	175791
10362563	10362586	19	-	26472758	Jiyoye	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	-0.4997152141026452	[149]	[79]	-4	hSpCas9	negative selection	175792
10357768	10357791	19	+	26472758	Jiyoye	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-0.20816076825880137	[71]	[46]	-1	hSpCas9	negative selection	175793
10356653	10356676	19	+	26472758	Jiyoye	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	0.7815708962873715	[53]	[69]	5	hSpCas9	negative selection	175794
10365547	10365570	19	-	26472758	KBM7	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	0.5531947705960942	[672,535]	[333,485]	6	hSpCas9	negative selection	366903
10356577	10356600	19	+	26472758	KBM7	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	0.1035348380655475	[407,497]	[226,236]	1	hSpCas9	negative selection	366904
10378261	10378284	19	+	26472758	KBM7	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	0.6272899646655462	[568,393]	[459,241]	7	hSpCas9	negative selection	366905
10366475	10366498	19	+	26472758	KBM7	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-0.21871965527289106	[1165,957]	[362,483]	-2	hSpCas9	negative selection	366906
10365534	10365557	19	-	26472758	KBM7	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-0.37823672452905344	[540,432]	[164,183]	-3	hSpCas9	negative selection	366907
10364715	10364738	19	+	26472758	KBM7	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.6219861127213815	[230,312]	[175,222]	6	hSpCas9	negative selection	366908
10364638	10364661	19	+	26472758	KBM7	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	1.6581359020544673	[27,30]	[58,30]	9	hSpCas9	negative selection	366909
10362563	10362586	19	-	26472758	KBM7	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	0.8904292084759293	[309,424]	[496,174]	8	hSpCas9	negative selection	366910
10357768	10357791	19	+	26472758	KBM7	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-1.5751563989747825	[389,289]	[69,37]	-8	hSpCas9	negative selection	366911
10356653	10356676	19	+	26472758	KBM7	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	0.2522677694338212	[274,355]	[238,126]	2	hSpCas9	negative selection	366912
10365547	10365570	19	-	26472758	Raji	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	0.39689015256858445	[251]	[76]	4	hSpCas9	negative selection	558021
10356577	10356600	19	+	26472758	Raji	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	-0.8686906253809199	[298]	[37]	-6	hSpCas9	negative selection	558022
10378261	10378284	19	+	26472758	Raji	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	0.5098209978728098	[229]	[75]	5	hSpCas9	negative selection	558023
10366475	10366498	19	+	26472758	Raji	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-0.27643909323970506	[380]	[72]	-2	hSpCas9	negative selection	558024
10365534	10365557	19	-	26472758	Raji	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-0.74212483809895	[381]	[52]	-5	hSpCas9	negative selection	558025
10364715	10364738	19	+	26472758	Raji	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.5858464147940768	[88]	[30]	5	hSpCas9	negative selection	558026
10364638	10364661	19	+	26472758	Raji	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.47935231276055745	[33]	[10]	4	hSpCas9	negative selection	558027
10362563	10362586	19	-	26472758	Raji	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	0.11772547959505841	[138]	[34]	1	hSpCas9	negative selection	558028
10357768	10357791	19	+	26472758	Raji	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-2.159403005321302	[153]	[7]	-8	hSpCas9	negative selection	558029
10356653	10356676	19	+	26472758	Raji	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	-0.20438469329354125	[282]	[56]	-2	hSpCas9	negative selection	558030
10365547	10365570	19	-	26472758	K562	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	1.3136230903652406	[579]	[1216]	9	hSpCas9	negative selection	749139
10356577	10356600	19	+	26472758	K562	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	0.23916300221495154	[274]	[273]	1	hSpCas9	negative selection	749140
10378261	10378284	19	+	26472758	K562	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	-0.04552355163086402	[367]	[300]	0	hSpCas9	negative selection	749141
10366475	10366498	19	+	26472758	K562	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-0.6209768066242323	[633]	[347]	-4	hSpCas9	negative selection	749142
10365534	10365557	19	-	26472758	K562	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	0.008281214795504699	[456]	[387]	0	hSpCas9	negative selection	749143
10364715	10364738	19	+	26472758	K562	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.6454396485639902	[180]	[238]	5	hSpCas9	negative selection	749144
10364638	10364661	19	+	26472758	K562	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	2.2066166949540627	[28]	[112]	9	hSpCas9	negative selection	749145
10362563	10362586	19	-	26472758	K562	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	-0.8775717967121636	[295]	[135]	-5	hSpCas9	negative selection	749146
10357768	10357791	19	+	26472758	K562	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-0.6097304058700982	[234]	[129]	-4	hSpCas9	negative selection	749147
10356653	10356676	19	+	26472758	K562	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	0.22310822142103476	[340]	[335]	1	hSpCas9	negative selection	749148
10364638	10364661	19	+	26627737	DLD1	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.215418890201172	[1775]	[597,885,484]	2	hSpCas9	negative selection	802314
10364865	10364888	19	-	26627737	DLD1	viability	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	-0.8208161462135897	[688]	[99,145,120]	-7	hSpCas9	negative selection	802315
10365861	10365884	19	+	26627737	DLD1	viability	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-1.1537462846363291	[350]	[0,121,30]	-7	hSpCas9	negative selection	802316
10366493	10366516	19	+	26627737	DLD1	viability	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.9617144347569997	[412]	[234,273,246]	8	hSpCas9	negative selection	802317
10368159	10368182	19	-	26627737	DLD1	viability	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	-0.02485365819669827	[1433]	[525,299,482]	0	hSpCas9	negative selection	802318
10378260	10378283	19	+	26627737	DLD1	viability	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.3211199329612806	[249]	[161,59,72]	3	hSpCas9	negative selection	802319
10364638	10364661	19	+	26627737	GBM cells	viability after 5 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.22261106262610375	[651]	[395,419]	3	hSpCas9	negative selection	884629
10364865	10364888	19	-	26627737	GBM cells	viability after 5 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.6069347720111797	[291]	[243,232]	8	hSpCas9	negative selection	884630
10365861	10365884	19	+	26627737	GBM cells	viability after 5 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	1.3242197096183563	[34]	[47,45]	9	hSpCas9	negative selection	884631
10366493	10366516	19	+	26627737	GBM cells	viability after 5 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.5813693373106315	[533]	[365,490]	8	hSpCas9	negative selection	884632
10368159	10368182	19	-	26627737	GBM cells	viability after 5 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	-0.4645564822448607	[686]	[259,273]	-6	hSpCas9	negative selection	884633
10378260	10378283	19	+	26627737	GBM cells	viability after 5 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	-0.22730384131773418	[190]	[86,87]	-4	hSpCas9	negative selection	884634
10364638	10364661	19	+	26627737	GBM cells	viability after 13 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.4766654648662627	[651]	[542,450]	6	hSpCas9	negative selection	966944
10364865	10364888	19	-	26627737	GBM cells	viability after 13 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.43329934908677614	[291]	[294,147]	5	hSpCas9	negative selection	966945
10365861	10365884	19	+	26627737	GBM cells	viability after 13 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	0.47993973128941736	[34]	[31,21]	6	hSpCas9	negative selection	966946
10366493	10366516	19	+	26627737	GBM cells	viability after 13 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.34294989956551625	[533]	[447,301]	4	hSpCas9	negative selection	966947
10368159	10368182	19	-	26627737	GBM cells	viability after 13 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	-0.35871969434275286	[686]	[368,226]	-4	hSpCas9	negative selection	966948
10378260	10378283	19	+	26627737	GBM cells	viability after 13 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	-0.11612070501728466	[190]	[88,100]	-1	hSpCas9	negative selection	966949
10364638	10364661	19	+	26627737	GBM cells	viability after 21 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.4859599801052523	[651]	[493,497]	5	hSpCas9	negative selection	1049259
10364865	10364888	19	-	26627737	GBM cells	viability after 21 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.4247420220938468	[291]	[225,200]	4	hSpCas9	negative selection	1049260
10365861	10365884	19	+	26627737	GBM cells	viability after 21 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	0.12483045719277586	[34]	[26,14]	1	hSpCas9	negative selection	1049261
10366493	10366516	19	+	26627737	GBM cells	viability after 21 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.584040407112596	[533]	[460,410]	6	hSpCas9	negative selection	1049262
10368159	10368182	19	-	26627737	GBM cells	viability after 21 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	-0.4930564699829184	[686]	[295,236]	-4	hSpCas9	negative selection	1049263
10378260	10378283	19	+	26627737	GBM cells	viability after 21 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.16877825746101255	[190]	[124,108]	1	hSpCas9	negative selection	1049264
10364638	10364661	19	+	26627737	RPE1	viability after 9 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.33838192705129866	[2924]	[959,1412]	2	hSpCas9	negative selection	1131574
10364865	10364888	19	-	26627737	RPE1	viability after 9 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.6721327394447383	[883]	[495,369]	4	hSpCas9	negative selection	1131575
10365861	10365884	19	+	26627737	RPE1	viability after 9 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	7.13256724818429	[1]	[17,177]	9	hSpCas9	negative selection	1131576
10366493	10366516	19	+	26627737	RPE1	viability after 9 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	-0.2136785143777562	[1857]	[491,513]	-1	hSpCas9	negative selection	1131577
10368159	10368182	19	-	26627737	RPE1	viability after 9 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.09116624452128463	[1607]	[537,533]	0	hSpCas9	negative selection	1131578
10378260	10378283	19	+	26627737	RPE1	viability after 9 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.07248312558500242	[626]	[253,144]	0	hSpCas9	negative selection	1131579
10364638	10364661	19	+	26627737	RPE1	viability after 12 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.532508201172804	[2924]	[1125,1147]	3	hSpCas9	negative selection	1213889
10364865	10364888	19	-	26627737	RPE1	viability after 12 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.6004054065444134	[883]	[345,374]	4	hSpCas9	negative selection	1213890
10365861	10365884	19	+	26627737	RPE1	viability after 12 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	6.926069045139844	[1]	[8,124]	9	hSpCas9	negative selection	1213891
10366493	10366516	19	+	26627737	RPE1	viability after 12 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	-0.47581299625799134	[1857]	[356,360]	-3	hSpCas9	negative selection	1213892
10368159	10368182	19	-	26627737	RPE1	viability after 12 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.29272897188552327	[1607]	[484,575]	2	hSpCas9	negative selection	1213893
10378260	10378283	19	+	26627737	RPE1	viability after 12 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.08206825828033826	[626]	[239,112]	0	hSpCas9	negative selection	1213894
10364638	10364661	19	+	26627737	RPE1	viability after 15 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.6634470373888834	[2924]	[1618,1012]	4	hSpCas9	negative selection	1296204
10364865	10364888	19	-	26627737	RPE1	viability after 15 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	1.117247423642051	[883]	[740,350]	6	hSpCas9	negative selection	1296205
10365861	10365884	19	+	26627737	RPE1	viability after 15 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	6.965184034129629	[1]	[59,80]	9	hSpCas9	negative selection	1296206
10366493	10366516	19	+	26627737	RPE1	viability after 15 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	-0.8956904092931637	[1857]	[366,200]	-5	hSpCas9	negative selection	1296207
10368159	10368182	19	-	26627737	RPE1	viability after 15 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.16950455906139306	[1607]	[450,569]	1	hSpCas9	negative selection	1296208
10378260	10378283	19	+	26627737	RPE1	viability after 15 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.5818846430231754	[626]	[350,182]	3	hSpCas9	negative selection	1296209
10364638	10364661	19	+	26627737	RPE1	viability after 18 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.5954760279797424	[2924]	[1329,1045]	4	hSpCas9	negative selection	1378519
10364865	10364888	19	-	26627737	RPE1	viability after 18 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	1.0819594350924102	[883]	[592,410]	6	hSpCas9	negative selection	1378520
10365861	10365884	19	+	26627737	RPE1	viability after 18 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	6.651755043330272	[1]	[32,76]	9	hSpCas9	negative selection	1378521
10366493	10366516	19	+	26627737	RPE1	viability after 18 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	-0.5597317100784946	[1857]	[388,287]	-4	hSpCas9	negative selection	1378522
10368159	10368182	19	-	26627737	RPE1	viability after 18 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.19856358093046844	[1607]	[409,591]	1	hSpCas9	negative selection	1378523
10378260	10378283	19	+	26627737	RPE1	viability after 18 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	-0.043476312483874735	[626]	[256,64]	0	hSpCas9	negative selection	1378524
10364638	10364661	19	+	26627737	HeLa	viability after 8 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	1.286481076652525	[625]	[742,474,783]	8	hSpCas9	negative selection	1460834
10364865	10364888	19	-	26627737	HeLa	viability after 8 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.5451642277254884	[374]	[487,171,117]	5	hSpCas9	negative selection	1460835
10365861	10365884	19	+	26627737	HeLa	viability after 8 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-0.07853075608723073	[367]	[113,200,132]	0	hSpCas9	negative selection	1460836
10366493	10366516	19	+	26627737	HeLa	viability after 8 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.28069120079787213	[827]	[572,423,351]	2	hSpCas9	negative selection	1460837
10368159	10368182	19	-	26627737	HeLa	viability after 8 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.3030660325346677	[820]	[628,416,325]	3	hSpCas9	negative selection	1460838
10378260	10378283	19	+	26627737	HeLa	viability after 8 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.9672039828912713	[162]	[264,131,52]	7	hSpCas9	negative selection	1460839
10364638	10364661	19	+	26627737	HeLa	viability after 12 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	1.4621756753953625	[625]	[1089,564,509]	8	hSpCas9	negative selection	1543149
10364865	10364888	19	-	26627737	HeLa	viability after 12 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.6673832273138939	[374]	[132,180,427]	5	hSpCas9	negative selection	1543150
10365861	10365884	19	+	26627737	HeLa	viability after 12 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-1.5303053250372367	[367]	[34,103,12]	-8	hSpCas9	negative selection	1543151
10366493	10366516	19	+	26627737	HeLa	viability after 12 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.22755706383471708	[827]	[375,364,463]	2	hSpCas9	negative selection	1543152
10368159	10368182	19	-	26627737	HeLa	viability after 12 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.1742170583450231	[820]	[211,472,448]	1	hSpCas9	negative selection	1543153
10378260	10378283	19	+	26627737	HeLa	viability after 12 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.40490390651275154	[162]	[149,63,57]	3	hSpCas9	negative selection	1543154
10364638	10364661	19	+	26627737	HeLa	viability after 15 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	1.2389861064039764	[625]	[570,486,758]	8	hSpCas9	negative selection	1625464
10364865	10364888	19	-	26627737	HeLa	viability after 15 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	1.1206053090170331	[374]	[474,331,174]	7	hSpCas9	negative selection	1625465
10365861	10365884	19	+	26627737	HeLa	viability after 15 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-2.551307748014625	[367]	[7,17,52]	-9	hSpCas9	negative selection	1625466
10366493	10366516	19	+	26627737	HeLa	viability after 15 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.22039843121927816	[827]	[276,396,514]	1	hSpCas9	negative selection	1625467
10368159	10368182	19	-	26627737	HeLa	viability after 15 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.13073393686879298	[820]	[148,604,344]	1	hSpCas9	negative selection	1625468
10378260	10378283	19	+	26627737	HeLa	viability after 15 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.4943110009966931	[162]	[118,104,52]	4	hSpCas9	negative selection	1625469
10364638	10364661	19	+	26627737	HeLa	viability after 18 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	1.2632910317580697	[625]	[403,401,758]	8	hSpCas9	negative selection	1707779
10364865	10364888	19	-	26627737	HeLa	viability after 18 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	1.1610700487495826	[374]	[332,279,174]	7	hSpCas9	negative selection	1707780
10365861	10365884	19	+	26627737	HeLa	viability after 18 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-2.513821563737484	[367]	[4,16,52]	-9	hSpCas9	negative selection	1707781
10366493	10366516	19	+	26627737	HeLa	viability after 18 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.21540587784364007	[827]	[186,323,514]	1	hSpCas9	negative selection	1707782
10368159	10368182	19	-	26627737	HeLa	viability after 18 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.15098409034423055	[820]	[97,515,344]	1	hSpCas9	negative selection	1707783
10378260	10378283	19	+	26627737	HeLa	viability after 18 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.5700523563010439	[162]	[87,88,52]	4	hSpCas9	negative selection	1707784
10364638	10364661	19	+	26627737	HCT116	viability after 6 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	1.7553363934750885	[1577]	[725,898]	8	hSpCas9	negative selection	1790094
10364865	10364888	19	-	26627737	HCT116	viability after 6 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	-0.4795874825480157	[550]	[123,27]	-3	hSpCas9	negative selection	1790095
10365861	10365884	19	+	26627737	HCT116	viability after 6 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-1.0550744005610162	[278]	[33,13]	-6	hSpCas9	negative selection	1790096
10366493	10366516	19	+	26627737	HCT116	viability after 6 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	-1.504713251975923	[1100]	[89,44]	-7	hSpCas9	negative selection	1790097
10368159	10368182	19	-	26627737	HCT116	viability after 6 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.5530347109689155	[1705]	[941,90]	3	hSpCas9	negative selection	1790098
10378260	10378283	19	+	26627737	HCT116	viability after 6 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	-1.857016426939643	[599]	[65,3]	-8	hSpCas9	negative selection	1790099
10364638	10364661	19	+	26627737	HCT116	viability after 8 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.10171192692076292	[798]	[346,673,394]	1	hSpCas9	negative selection	1872409
10364865	10364888	19	-	26627737	HCT116	viability after 8 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.21843952471456934	[360]	[210,172,308]	2	hSpCas9	negative selection	1872410
10365861	10365884	19	+	26627737	HCT116	viability after 8 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-0.5583757597729178	[227]	[97,58,98]	-6	hSpCas9	negative selection	1872411
10366493	10366516	19	+	26627737	HCT116	viability after 8 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.0016046162394183217	[741]	[402,428,395]	0	hSpCas9	negative selection	1872412
10368159	10368182	19	-	26627737	HCT116	viability after 8 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.42778587826889924	[565]	[403,490,363]	4	hSpCas9	negative selection	1872413
10378260	10378283	19	+	26627737	HCT116	viability after 8 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	-0.450991997676761	[281]	[109,120,109]	-5	hSpCas9	negative selection	1872414
10364638	10364661	19	+	26627737	HCT116	viability after 9 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.7100154445261968	[1577]	[557,792]	5	hSpCas9	negative selection	1954724
10364865	10364888	19	-	26627737	HCT116	viability after 9 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	1.3736833528833514	[550]	[354,401]	8	hSpCas9	negative selection	1954725
10365861	10365884	19	+	26627737	HCT116	viability after 9 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	0.8679490179842844	[278]	[245,48]	6	hSpCas9	negative selection	1954726
10366493	10366516	19	+	26627737	HCT116	viability after 9 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.21405710142011658	[1100]	[359,325]	1	hSpCas9	negative selection	1954727
10368159	10368182	19	-	26627737	HCT116	viability after 9 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	-0.5158749366308123	[1705]	[436,224]	-4	hSpCas9	negative selection	1954728
10378260	10378283	19	+	26627737	HCT116	viability after 9 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	-0.36137573394342604	[599]	[136,114]	-3	hSpCas9	negative selection	1954729
10364638	10364661	19	+	26627737	HCT116	viability after 12 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.06065397548278462	[798]	[411,641,266]	0	hSpCas9	negative selection	2037039
10364865	10364888	19	-	26627737	HCT116	viability after 12 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.12145008980397365	[360]	[251,159,201]	1	hSpCas9	negative selection	2037040
10365861	10365884	19	+	26627737	HCT116	viability after 12 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-1.2150224946145043	[227]	[37,49,67]	-8	hSpCas9	negative selection	2037041
10366493	10366516	19	+	26627737	HCT116	viability after 12 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	-0.3264143548223578	[741]	[259,416,262]	-3	hSpCas9	negative selection	2037042
10368159	10368182	19	-	26627737	HCT116	viability after 12 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.7354236720705556	[565]	[619,507,346]	6	hSpCas9	negative selection	2037043
10378260	10378283	19	+	26627737	HCT116	viability after 12 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	-0.7216272095757004	[281]	[87,57,122]	-7	hSpCas9	negative selection	2037044
10364638	10364661	19	+	26627737	HCT116	viability after 15 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.4325285434371129	[798]	[613,690,552]	4	hSpCas9	negative selection	2119354
10364865	10364888	19	-	26627737	HCT116	viability after 15 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.4244808766196156	[360]	[347,281,213]	4	hSpCas9	negative selection	2119355
10365861	10365884	19	+	26627737	HCT116	viability after 15 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-0.788186548574044	[227]	[79,73,73]	-7	hSpCas9	negative selection	2119356
10366493	10366516	19	+	26627737	HCT116	viability after 15 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.14961587463174753	[741]	[511,449,460]	1	hSpCas9	negative selection	2119357
10368159	10368182	19	-	26627737	HCT116	viability after 15 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.7219017465903219	[565]	[649,416,554]	6	hSpCas9	negative selection	2119358
10378260	10378283	19	+	26627737	HCT116	viability after 15 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	-0.48533785317335476	[281]	[195,58,101]	-5	hSpCas9	negative selection	2119359
10364638	10364661	19	+	26627737	HCT116	viability after 18 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.8506908920026051	[798]	[832,852,378]	6	hSpCas9	negative selection	2201669
10364865	10364888	19	-	26627737	HCT116	viability after 18 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.36605193011333287	[360]	[219,327,114]	3	hSpCas9	negative selection	2201670
10365861	10365884	19	+	26627737	HCT116	viability after 18 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-0.9483286270732609	[227]	[85,56,26]	-7	hSpCas9	negative selection	2201671
10366493	10366516	19	+	26627737	HCT116	viability after 18 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	-0.639653504657974	[741]	[247,237,202]	-5	hSpCas9	negative selection	2201672
10368159	10368182	19	-	26627737	HCT116	viability after 18 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.48087727367566213	[565]	[386,410,343]	4	hSpCas9	negative selection	2201673
10378260	10378283	19	+	26627737	HCT116	viability after 18 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	-0.36233327598243137	[281]	[94,111,110]	-3	hSpCas9	negative selection	2201674
10378211	10378234	19	+	24336569	HL60	viability	CACCAACTTTATGTGCAATGTGG	TYK2	ENSG00000105397	0.6985740312701105	[1111]	[3818]	6	hSpCas9	negative selection	2304495
10378244	10378267	19	-	24336569	HL60	viability	TGAGTCATCGCTGACAGCTGAGG	TYK2	ENSG00000105397	-0.4844195761542779	[871]	[1318]	-4	hSpCas9	negative selection	2304496
10378260	10378283	19	+	24336569	HL60	viability	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.25440318521633987	[205]	[519]	2	hSpCas9	negative selection	2304497
10378287	10378310	19	-	24336569	HL60	viability	ACTGGGCTGGTCCAGGCGGCGGG	TYK2	ENSG00000105397	0.9156705656767145	[755]	[3017]	7	hSpCas9	negative selection	2304498
10378304	10378327	19	+	24336569	HL60	viability	CCCAGTGCAGAAGCACCTTCAGG	TYK2	ENSG00000105397	0.5706125959507968	[342]	[1077]	5	hSpCas9	negative selection	2304499
10378314	10378337	19	+	24336569	HL60	viability	AAGCACCTTCAGGCCTCCCATGG	TYK2	ENSG00000105397	-0.2757329210509563	[634]	[1109]	-2	hSpCas9	negative selection	2304500
10378319	10378342	19	-	24336569	HL60	viability	GGCTGCCATGGGAGGCCTGAAGG	TYK2	ENSG00000105397	-0.10638728733230418	[904]	[1778]	-1	hSpCas9	negative selection	2304501
10378324	10378347	19	+	24336569	HL60	viability	AGGCCTCCCATGGCAGCCATGGG	TYK2	ENSG00000105397	1.041790467382759	[554]	[2417]	7	hSpCas9	negative selection	2304502
10378329	10378352	19	+	24336569	HL60	viability	TCCCATGGCAGCCATGGGCTGGG	TYK2	ENSG00000105397	-0.35709854324232354	[758]	[1253]	-3	hSpCas9	negative selection	2304503
10378388	10378411	19	-	24336569	HL60	viability	GAGCATGCCTCTGCGCCACTGGG	TYK2	ENSG00000105397	0.8519381506420798	[531]	[2031]	7	hSpCas9	negative selection	2304504
10378211	10378234	19	+	24336569	KBM7	viability	CACCAACTTTATGTGCAATGTGG	TYK2	ENSG00000105397	0.5600653637974611	[846]	[3405]	5	hSpCas9	negative selection	2371672
10378244	10378267	19	-	24336569	KBM7	viability	TGAGTCATCGCTGACAGCTGAGG	TYK2	ENSG00000105397	0.47075212097387953	[694]	[2626]	4	hSpCas9	negative selection	2371673
10378260	10378283	19	+	24336569	KBM7	viability	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.8935324548996535	[253]	[1286]	7	hSpCas9	negative selection	2371674
10378287	10378310	19	-	24336569	KBM7	viability	ACTGGGCTGGTCCAGGCGGCGGG	TYK2	ENSG00000105397	0.7744802311240238	[618]	[2887]	7	hSpCas9	negative selection	2371675
10378304	10378327	19	+	24336569	KBM7	viability	CCCAGTGCAGAAGCACCTTCAGG	TYK2	ENSG00000105397	0.24356049372830293	[418]	[1352]	2	hSpCas9	negative selection	2371676
10378314	10378337	19	+	24336569	KBM7	viability	AAGCACCTTCAGGCCTCCCATGG	TYK2	ENSG00000105397	-0.47218116978196073	[620]	[1220]	-4	hSpCas9	negative selection	2371677
10378319	10378342	19	-	24336569	KBM7	viability	GGCTGCCATGGGAGGCCTGAAGG	TYK2	ENSG00000105397	0.44442489224516	[564]	[2096]	4	hSpCas9	negative selection	2371678
10378324	10378347	19	+	24336569	KBM7	viability	AGGCCTCCCATGGCAGCCATGGG	TYK2	ENSG00000105397	0.7102176131392349	[583]	[2605]	6	hSpCas9	negative selection	2371679
10378329	10378352	19	+	24336569	KBM7	viability	TCCCATGGCAGCCATGGGCTGGG	TYK2	ENSG00000105397	0.949310956019702	[404]	[2132]	7	hSpCas9	negative selection	2371680
10378388	10378411	19	-	24336569	KBM7	viability	GAGCATGCCTCTGCGCCACTGGG	TYK2	ENSG00000105397	1.2495820817599799	[304]	[1977]	8	hSpCas9	negative selection	2371681
10355817	10355840	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGCCCACCACCACGCCGGG	TYK2	ENSG00000105397	1.906510521561382	[74,11]	[56,10]	6	dCas9-VP64	positive selection	2400642
10380644	10380667	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAATCCAATGGTGACGAGCAGGG	TYK2	ENSG00000105397	2.9643871448094488	[179,9]	[295,15]	8	dCas9-VP64	positive selection	2432410
10355817	10355840	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGCCCACCACCACGCCGGG	TYK2	ENSG00000105397	1.1664475786686166	[321,97]	[88,216]	7	dCas9-VP64	positive selection	2495897
10380644	10380667	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAATCCAATGGTGACGAGCAGGG	TYK2	ENSG00000105397	-0.40635084374090574	[219,34]	[49,13]	-4	dCas9-VP64	positive selection	2527665
10365733	10365756	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATACCTAGCCACACTCGAGCGG	TYK2	ENSG00000105397	-0.2234870928809931	[2,3]	[1,1]	-3	hSpCas9	positive selection	3030358
10368100	10368123	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCAGATCAGACAGCACAGGGG	TYK2	ENSG00000105397	-0.26284267259624483	[4,3]	[3,1]	-4	hSpCas9	positive selection	3030359
10365733	10365756	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATACCTAGCCACACTCGAGCGG	TYK2	ENSG00000105397	0.4764400114101645	[2,2]	[2,1]	7	hSpCas9	positive selection	3098216
10368100	10368123	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCAGATCAGACAGCACAGGGG	TYK2	ENSG00000105397	0.36348477272756075	[4,4]	[4,3]	6	hSpCas9	positive selection	3098217
10362431	10362454		+	24336571	A375	resistance to PLX after 7 days	CGCAAGCTCTGCATGCCGTCTGG	TYK2	ENSG00000105397	0.0013075429044802078	[21,21]	[21,21]	0	hSpCas9	positive selection	3153726
10362352	10362375		-	24336571	A375	resistance to PLX after 7 days	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	0.0284652939220274	[15,14]	[15,15]	1	hSpCas9	positive selection	3153727
10364715	10364738		+	24336571	A375	resistance to PLX after 7 days	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.1422487558749328	[6,5]	[7,6]	4	hSpCas9	positive selection	3153729
10364699	10364722		-	24336571	A375	resistance to PLX after 7 days	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.06756962410165301	[3,3]	[3,3]	-2	hSpCas9	positive selection	3153730
10362431	10362454		+	24336571	A375	resistance to PLX after 14 days	CGCAAGCTCTGCATGCCGTCTGG	TYK2	ENSG00000105397	-0.9965899033097143	[24,32]	[5,5]	-9	hSpCas9	positive selection	3211519
10362352	10362375		-	24336571	A375	resistance to PLX after 14 days	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.28873701036283766	[16,17]	[5,5]	-3	hSpCas9	positive selection	3211520
10364715	10364738		+	24336571	A375	resistance to PLX after 14 days	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.7615893431412384	[6,6]	[4,6]	6	hSpCas9	positive selection	3211522
10364699	10364722		-	24336571	A375	resistance to PLX after 14 days	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.15767923721808463	[1,4]	[1,1]	1	hSpCas9	positive selection	3211523
10362431	10362454		+	24336571	A375	viability after 7 days	CGCAAGCTCTGCATGCCGTCTGG	TYK2	ENSG00000105397	0.2347431631247704	[19]	[21,21]	3	hSpCas9	negative selection	3269312
10362352	10362375		-	24336571	A375	viability after 7 days	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.3823462742812415	[21]	[15,14]	-5	hSpCas9	negative selection	3269313
10364715	10364738		+	24336571	A375	viability after 7 days	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.21942729661269	[7]	[6,5]	-3	hSpCas9	negative selection	3269315
10364699	10364722		-	24336571	A375	viability after 7 days	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.276632244848001	[2]	[3,3]	4	hSpCas9	negative selection	3269316
10362431	10362454		+	24336571	A375	viability after 14 days	CGCAAGCTCTGCATGCCGTCTGG	TYK2	ENSG00000105397	0.6360755636881085	[19]	[24,32]	7	hSpCas9	negative selection	3327105
10362352	10362375		-	24336571	A375	viability after 14 days	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.2251142874138221	[21]	[16,17]	-3	hSpCas9	negative selection	3327106
10364715	10364738		+	24336571	A375	viability after 14 days	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.09622733759579483	[7]	[6,6]	-1	hSpCas9	negative selection	3327108
10364699	10364722		-	24336571	A375	viability after 14 days	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.12009729152744719	[2]	[1,4]	1	hSpCas9	negative selection	3327109
10368143	10368166	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.20210540719146217	[175,175]	[0,0]	-1	hSpCas9	positive selection	3399862
10362340	10362363	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-1.0047686339243442	[306,306]	[0,0]	-6	hSpCas9	positive selection	3399863
10364699	10364722	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.16986337019549572	[135,135]	[0,0]	0	hSpCas9	positive selection	3399864
10365733	10365756	19	-	26780180	HT29	viability (Avana library 4 designs)	AATACCTAGCCACACTCGAGCGG	TYK2	ENSG00000105397	2.07939796759984	[]	[]	7	hSpCas9	negative selection	3469277
10368100	10368123	19	-	26780180	HT29	viability (Avana library 4 designs)	CCTCAGATCAGACAGCACAGGGG	TYK2	ENSG00000105397	1.25373681505286	[]	[]	5	hSpCas9	negative selection	3469278
10368388	10368411	19	+	26780180	HT29	viability (Avana library 4 designs)	GCAAAGAGATTGAAGCAAGGAGG	TYK2	ENSG00000105397	1.32877092721603	[]	[]	5	hSpCas9	negative selection	3469279
10365849	10365872	19	+	26780180	HT29	viability (Avana library 4 designs)	TGTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	0.976237267325334	[]	[]	4	hSpCas9	negative selection	3469280
10368388	10368411	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAAGAGATTGAAGCAAGGAGG	TYK2	ENSG00000105397	-3.05334253584965	[]	[]	-4	hSpCas9	negative selection	3574441
10365849	10365872	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	1.99476005357551	[]	[]	3	hSpCas9	negative selection	3574442
10368100	10368123	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCAGATCAGACAGCACAGGGG	TYK2	ENSG00000105397	-1.85415405224564	[]	[]	-2	hSpCas9	negative selection	3574443
10365733	10365756	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATACCTAGCCACACTCGAGCGG	TYK2	ENSG00000105397	-8.46479272635286	[]	[]	-7	hSpCas9	negative selection	3574444
10368388	10368411	19	+	26780180	A375	viability (Avana lentiGuide)	GCAAAGAGATTGAAGCAAGGAGG	TYK2	ENSG00000105397	6.48503643456527	[]	[]	5	hSpCas9	negative selection	3683100
10365849	10365872	19	+	26780180	A375	viability (Avana lentiGuide)	TGTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	-0.278216163429971	[]	[]	0	hSpCas9	negative selection	3683101
10368100	10368123	19	-	26780180	A375	viability (Avana lentiGuide)	CCTCAGATCAGACAGCACAGGGG	TYK2	ENSG00000105397	-3.78715683339888	[]	[]	-6	hSpCas9	negative selection	3683102
10365733	10365756	19	-	26780180	A375	viability (Avana lentiGuide)	AATACCTAGCCACACTCGAGCGG	TYK2	ENSG00000105397	-0.671372120703265	[]	[]	-1	hSpCas9	negative selection	3683103
10368388	10368411	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAAGAGATTGAAGCAAGGAGG	TYK2	ENSG00000105397	-0.3410879846871986	[4]	[3,3]	-5	hSpCas9	positive selection	3791707
10365849	10365872	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	0.1617260511089069	[4]	[5,4]	4	hSpCas9	positive selection	3791708
10368100	10368123	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCAGATCAGACAGCACAGGGG	TYK2	ENSG00000105397	-0.3581315842993658	[4]	[3,3]	-5	hSpCas9	positive selection	3791709
10365733	10365756	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATACCTAGCCACACTCGAGCGG	TYK2	ENSG00000105397	-0.154101287397893	[4]	[4,3]	-2	hSpCas9	positive selection	3791710
10368388	10368411	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAAGAGATTGAAGCAAGGAGG	TYK2	ENSG00000105397	0.12603958121899417	[5]	[5,4]	3	hSpCas9	positive selection	3900314
10365849	10365872	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	-0.24581552096850223	[5]	[2,4]	-3	hSpCas9	positive selection	3900315
10368100	10368123	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCAGATCAGACAGCACAGGGG	TYK2	ENSG00000105397	0.2745146081625266	[5]	[5,5]	7	hSpCas9	positive selection	3900316
10365733	10365756	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATACCTAGCCACACTCGAGCGG	TYK2	ENSG00000105397	-0.45383992532461936	[4]	[3,2]	-5	hSpCas9	positive selection	3900317
10362340	10362363	19	+	26780180	A375	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.958099331881297	[]	[]	4	hSpCas9	negative selection	4009417
10368143	10368166	19	-	26780180	A375	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	1.70100078098175	[]	[]	9	hSpCas9	negative selection	4009418
10362352	10362375	19	-	26780180	A375	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	0.468674216233137	[]	[]	1	hSpCas9	negative selection	4009419
10364715	10364738	19	+	26780180	A375	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	1.37564505775733	[]	[]	7	hSpCas9	negative selection	4009420
10364699	10364722	19	-	26780180	A375	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	1.31062939494805	[]	[]	7	hSpCas9	negative selection	4009421
10368294	10368317	19	-	26780180	A375	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.752805180077973	[]	[]	3	hSpCas9	negative selection	4009422
10362340	10362363	19	+	26780180	HT29	viability (GeCKOv2 library)	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	1.17238955925571	[]	[]	5	hSpCas9	negative selection	4117383
10368143	10368166	19	-	26780180	HT29	viability (GeCKOv2 library)	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	0.882713479412966	[]	[]	4	hSpCas9	negative selection	4117384
10362352	10362375	19	-	26780180	HT29	viability (GeCKOv2 library)	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	1.24489281952497	[]	[]	6	hSpCas9	negative selection	4117385
10364715	10364738	19	+	26780180	HT29	viability (GeCKOv2 library)	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	1.54622793627591	[]	[]	7	hSpCas9	negative selection	4117386
10364699	10364722	19	-	26780180	HT29	viability (GeCKOv2 library)	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.847868151211545	[]	[]	3	hSpCas9	negative selection	4117387
10368294	10368317	19	-	26780180	HT29	viability (GeCKOv2 library)	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.542904640047519	[]	[]	1	hSpCas9	negative selection	4117388
10362431	10362454	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCAAGCTCTGCATGCCGTCTGG	TYK2	ENSG00000105397	0.15729957784471066	[4]	[3,2]	4	hSpCas9	positive selection	4180379
10362352	10362375	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.05033891685834299	[4]	[2,2]	-1	hSpCas9	positive selection	4180380
10364715	10364738	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.02293665973122594	[2]	[0,2]	0	hSpCas9	positive selection	4180382
10364699	10364722	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.7319494106952616	[2]	[1,0]	-9	hSpCas9	positive selection	4180383
10362431	10362454	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCAAGCTCTGCATGCCGTCTGG	TYK2	ENSG00000105397	1.220983023101752	[3]	[3,0,4,5]	8	hSpCas9	positive selection	4244401
10362352	10362375	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.3174288113132742	[3]	[0,3,0,0]	-5	hSpCas9	positive selection	4244402
10364715	10364738	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.5468425429865131	[3]	[0,0,0,0]	-7	hSpCas9	positive selection	4244404
10364699	10364722	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.9569876249489748	[0]	[0,0,0,0]	6	hSpCas9	positive selection	4244405
10364715	10364738	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.3796872730917239	[2]	[1,0]	-7	hSpCas9	positive selection	4306075
10362352	10362375	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	0.24184160183700956	[2]	[2,2]	5	hSpCas9	positive selection	4306076
10368294	10368317	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.5972628222117037	[3]	[3,4]	9	hSpCas9	positive selection	4306077
10368143	10368166	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.3301077209862947	[3]	[2,0]	-6	hSpCas9	positive selection	4370324
10362340	10362363	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.04600314216877373	[3]	[2,2]	-1	hSpCas9	positive selection	4370325
10364699	10364722	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.14871075458815358	[2]	[2,1]	-3	hSpCas9	positive selection	4370326
10364699	10364721	19	-	27760321	OCIAML3	viability	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.09920178996018436	[868,703]	[568,767]	1	hSpCas9	negative selection	4451506
10365808	10365830	19	+	27760321	OCIAML3	viability	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4451507
10365850	10365872	19	+	27760321	OCIAML3	viability	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	0.3627966132646887	[891,717]	[844,752]	4	hSpCas9	negative selection	4451508
10368150	10368172	19	+	27760321	OCIAML3	viability	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	-0.3003614430207323	[609,527]	[293,446]	-3	hSpCas9	negative selection	4451509
10368294	10368316	19	-	27760321	OCIAML3	viability	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.17813499266463811	[288,290]	[260,252]	2	hSpCas9	negative selection	4451510
10364699	10364721	19	-	27760321	OCIAML2	viability	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.33634588312661495	[868,703]	[691,939]	4	hSpCas9	negative selection	4534969
10365808	10365830	19	+	27760321	OCIAML2	viability	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4534970
10365850	10365872	19	+	27760321	OCIAML2	viability	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	0.3473250065354221	[891,717]	[658,1040]	5	hSpCas9	negative selection	4534971
10368150	10368172	19	+	27760321	OCIAML2	viability	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	0.5045643607885986	[609,527]	[564,764]	7	hSpCas9	negative selection	4534972
10368294	10368316	19	-	27760321	OCIAML2	viability	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	-0.3388423552676427	[288,290]	[142,242]	-4	hSpCas9	negative selection	4534973
10364699	10364721	19	-	27760321	MV411	viability	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.3904634952246292	[868,703]	[802,486]	2	hSpCas9	negative selection	4618432
10365808	10365830	19	+	27760321	MV411	viability	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	0.5949485011219959	[0,0]	[0,0]	4	hSpCas9	negative selection	4618433
10365850	10365872	19	+	27760321	MV411	viability	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	-0.1593459213447328	[891,717]	[247,810]	-1	hSpCas9	negative selection	4618434
10368150	10368172	19	+	27760321	MV411	viability	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	-0.1250678781107939	[609,527]	[340,346]	-1	hSpCas9	negative selection	4618435
10368294	10368316	19	-	27760321	MV411	viability	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	-1.7582395029094535	[288,290]	[23,105]	-8	hSpCas9	negative selection	4618436
10364699	10364721	19	-	27760321	HL60	viability	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.332947797084	[868,703]	[518,494]	-4	hSpCas9	negative selection	4701895
10365808	10365830	19	+	27760321	HL60	viability	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4701896
10365850	10365872	19	+	27760321	HL60	viability	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	-0.08960022602332263	[891,717]	[681,542]	-1	hSpCas9	negative selection	4701897
10368150	10368172	19	+	27760321	HL60	viability	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	0.12978501180900204	[609,527]	[414,604]	1	hSpCas9	negative selection	4701898
10368294	10368316	19	-	27760321	HL60	viability	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	-0.13893721083101684	[288,290]	[212,218]	-1	hSpCas9	negative selection	4701899
10364699	10364721	19	-	27760321	HT1080	viability	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.06416946432676862	[703,549]	[268,205]	0	hSpCas9	negative selection	4785358
10365808	10365830	19	+	27760321	HT1080	viability	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4785359
10365850	10365872	19	+	27760321	HT1080	viability	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	-0.1868214392952684	[717,559]	[257,185]	-1	hSpCas9	negative selection	4785360
10368150	10368172	19	+	27760321	HT1080	viability	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	0.8640911490794598	[527,411]	[325,356]	5	hSpCas9	negative selection	4785361
10368294	10368316	19	-	27760321	HT1080	viability	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.651338302368215	[290,226]	[278,33]	3	hSpCas9	negative selection	4785362
10364699	10364721	19	-	27760321	HT29	viability after 7 days	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.009709969532442964	[703,549]	[879,831,733]	0	hSpCas9	negative selection	4868821
10365808	10365830	19	+	27760321	HT29	viability after 7 days	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	0.3747526856165386	[0,0]	[0,2,0]	6	hSpCas9	negative selection	4868822
10365850	10365872	19	+	27760321	HT29	viability after 7 days	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	0.49983592231513874	[717,559]	[1306,1126,1072]	7	hSpCas9	negative selection	4868823
10368150	10368172	19	+	27760321	HT29	viability after 7 days	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	0.20709432326036975	[527,411]	[739,764,595]	3	hSpCas9	negative selection	4868824
10368294	10368316	19	-	27760321	HT29	viability after 7 days	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	-0.6153907814084327	[290,226]	[152,189,296]	-7	hSpCas9	negative selection	4868825
10364699	10364721	19	-	27760321	HT29	viability after 25 days	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.3340406611294864	[703,549]	[706,695,1365]	3	hSpCas9	negative selection	4952284
10365808	10365830	19	+	27760321	HT29	viability after 25 days	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4952285
10365850	10365872	19	+	27760321	HT29	viability after 25 days	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	0.11997693614380234	[717,559]	[602,774,1038]	1	hSpCas9	negative selection	4952286
10368150	10368172	19	+	27760321	HT29	viability after 25 days	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	0.10533036888605934	[527,411]	[527,514,705]	1	hSpCas9	negative selection	4952287
10368294	10368316	19	-	27760321	HT29	viability after 25 days	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	-0.5471266708057139	[290,226]	[116,342,146]	-5	hSpCas9	negative selection	4952288
10364699	10364721	19	-	27760321	HT29	viability after 22 days	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.40275236862582076	[703,549]	[819,1169,887]	4	hSpCas9	negative selection	5035747
10365808	10365830	19	+	27760321	HT29	viability after 22 days	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5035748
10365850	10365872	19	+	27760321	HT29	viability after 22 days	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	0.4146452978671107	[717,559]	[997,1026,927]	4	hSpCas9	negative selection	5035749
10368150	10368172	19	+	27760321	HT29	viability after 22 days	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	0.32652784603691226	[527,411]	[723,724,592]	3	hSpCas9	negative selection	5035750
10368294	10368316	19	-	27760321	HT29	viability after 22 days	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	-0.8321368400945393	[290,226]	[104,256,143]	-6	hSpCas9	negative selection	5035751
10364699	10364721	19	-	27760321	HT29	viability after 19 days	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.4554298777866408	[703,549]	[983,1132,837]	4	hSpCas9	negative selection	5119210
10365808	10365830	19	+	27760321	HT29	viability after 19 days	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5119211
10365850	10365872	19	+	27760321	HT29	viability after 19 days	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	0.055384920856466846	[717,559]	[836,722,726]	0	hSpCas9	negative selection	5119212
10368150	10368172	19	+	27760321	HT29	viability after 19 days	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	0.19421512810082237	[527,411]	[652,325,859]	1	hSpCas9	negative selection	5119213
10368294	10368316	19	-	27760321	HT29	viability after 19 days	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	-0.3261584686034039	[290,226]	[277,385,55]	-3	hSpCas9	negative selection	5119214
10364699	10364721	19	-	27760321	HT29	viability after 16 days	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.4817564765448601	[703,549]	[816,957,1148]	5	hSpCas9	negative selection	5202673
10365808	10365830	19	+	27760321	HT29	viability after 16 days	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	2.1423140925671458	[0,0]	[13,0,0]	9	hSpCas9	negative selection	5202674
10365850	10365872	19	+	27760321	HT29	viability after 16 days	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	0.29056991786389563	[717,559]	[1156,672,824]	3	hSpCas9	negative selection	5202675
10368150	10368172	19	+	27760321	HT29	viability after 16 days	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	0.1781472437872566	[527,411]	[639,670,475]	2	hSpCas9	negative selection	5202676
10368294	10368316	19	-	27760321	HT29	viability after 16 days	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	-0.7036756873738417	[290,226]	[178,170,183]	-6	hSpCas9	negative selection	5202677
10364699	10364721	19	-	27760321	HT29	viability after 13 days	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.21184717146422538	[703,549]	[1011,690,824]	2	hSpCas9	negative selection	5286136
10365808	10365830	19	+	27760321	HT29	viability after 13 days	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5286137
10365850	10365872	19	+	27760321	HT29	viability after 13 days	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	0.36274498974371205	[717,559]	[1255,995,626]	4	hSpCas9	negative selection	5286138
10368150	10368172	19	+	27760321	HT29	viability after 13 days	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	0.09659297080790158	[527,411]	[663,540,545]	1	hSpCas9	negative selection	5286139
10368294	10368316	19	-	27760321	HT29	viability after 13 days	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	-0.8082269417957166	[290,226]	[175,188,150]	-7	hSpCas9	negative selection	5286140
10364699	10364721	19	-	27760321	HT29	viability after 10 days	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.05403031831835359	[703,549]	[715,1032,697]	0	hSpCas9	negative selection	5369599
10365808	10365830	19	+	27760321	HT29	viability after 10 days	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5369600
10365850	10365872	19	+	27760321	HT29	viability after 10 days	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	0.3178236774501073	[717,559]	[1060,802,1110]	4	hSpCas9	negative selection	5369601
10368150	10368172	19	+	27760321	HT29	viability after 10 days	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	-0.018730170403023105	[527,411]	[728,278,717]	0	hSpCas9	negative selection	5369602
10368294	10368316	19	-	27760321	HT29	viability after 10 days	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	-0.5648921725167402	[290,226]	[161,328,168]	-6	hSpCas9	negative selection	5369603
10364699	10364721	19	-	27760321	MOLM13	viability	GACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.05597649797755466	[868,703]	[265,622]	0	hSpCas9	negative selection	5453062
10365808	10365830	19	+	27760321	MOLM13	viability	CCTGCGGAAGACGTTCCGAAGG	TYK2	ENSG00000105397	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5453063
10365850	10365872	19	+	27760321	MOLM13	viability	GTGCTGCCGGATATGCCGGCGG	TYK2	ENSG00000105397	0.9066825005368397	[891,717]	[574,1077]	6	hSpCas9	negative selection	5453064
10368150	10368172	19	+	27760321	MOLM13	viability	GGTACACAGCCGGTTCCCGAGG	TYK2	ENSG00000105397	-0.7300967764540367	[609,527]	[306,95]	-4	hSpCas9	negative selection	5453065
10368294	10368316	19	-	27760321	MOLM13	viability	GATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.1986488334678222	[288,290]	[121,244]	1	hSpCas9	negative selection	5453066
10379993	10380016	19	+	27661255	K562	viability	GGCGCCAGTATGGAAGTGGAGGG	TYK2	ENSG00000105397	-0.06004897334618242	[408,457]	[351,313]	-2	dCas9-KRAB	negative selection	5520871
10380446	10380469	19	+	27661255	K562	viability	GTCCCCGCGGCTTCTTCCTGAGG	TYK2	ENSG00000105397	-0.10016424509003596	[313,232]	[239,174]	-4	dCas9-KRAB	negative selection	5520872
10380498	10380521	19	+	27661255	K562	viability	GTCCAGACTCACCCTTCCGGGGG	TYK2	ENSG00000105397	-0.012174191966535505	[813,798]	[685,598]	0	dCas9-KRAB	negative selection	5520873
10380462	10380485	19	-	27661255	K562	viability	GAGCGCGGCCGGAGGTCCTCAGG	TYK2	ENSG00000105397	0.0514346128177907	[762,831]	[751,579]	1	dCas9-KRAB	negative selection	5520874
10380493	10380516	19	-	27661255	K562	viability	GGAAGGGTGAGTCTGGACGCGGG	TYK2	ENSG00000105397	0.1951047952094721	[1459,1359]	[1499,1112]	6	dCas9-KRAB	negative selection	5520875
10380509	10380532	19	-	27661255	K562	viability	GAGCTTGTGTTCCCCCGGAAGGG	TYK2	ENSG00000105397	-1.2391689179526622	[1462,1479]	[533,466]	-8	dCas9-KRAB	negative selection	5520876
10380514	10380537	19	-	27661255	K562	viability	GGTTCGAGCTTGTGTTCCCCCGG	TYK2	ENSG00000105397	0.10396429351729042	[1409,1699]	[1418,1254]	3	dCas9-KRAB	negative selection	5520877
10364715	10364738	19	+	27260156	BXPC3	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.07946361621057796	[268]	[257,235,266,309]	-2	hSpCas9	negative selection	5578535
10362352	10362375	19	-	27260156	BXPC3	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.0135635937968962	[297]	[277,288,295,382]	0	hSpCas9	negative selection	5578536
10368294	10368317	19	-	27260156	BXPC3	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.08545668563758513	[701]	[704,691,792,954]	1	hSpCas9	negative selection	5578537
10368143	10368166	19	-	27260156	BXPC3	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.006522401968326735	[525]	[471,547,617,558]	0	hSpCas9	negative selection	5642784
10362340	10362363	19	+	27260156	BXPC3	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.050826933690668874	[552]	[492,606,395,758]	-1	hSpCas9	negative selection	5642785
10364699	10364722	19	-	27260156	BXPC3	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.0037692634766710587	[362]	[345,365,406,399]	0	hSpCas9	negative selection	5642786
10364715	10364738	19	+	27260156	A673	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.043560153569442206	[268]	[342,307,345,255]	-1	hSpCas9	negative selection	5699786
10362352	10362375	19	-	27260156	A673	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.18492390504347034	[297]	[424,249,343,249]	-4	hSpCas9	negative selection	5699787
10368294	10368317	19	-	27260156	A673	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.18425252914093393	[701]	[1134,877,943,890]	4	hSpCas9	negative selection	5699788
10368143	10368166	19	-	27260156	A673	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	0.0865754428555926	[525]	[764,659,685,575]	2	hSpCas9	negative selection	5764035
10362340	10362363	19	+	27260156	A673	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.0644129173324399	[552]	[697,649,750,676]	1	hSpCas9	negative selection	5764036
10364699	10364722	19	-	27260156	A673	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.09182497673346535	[362]	[398,413,379,442]	-2	hSpCas9	negative selection	5764037
10364715	10364738	19	+	27260156	A375	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.1821847916601409	[268]	[284,490,469,213]	2	hSpCas9	negative selection	5821037
10362352	10362375	19	-	27260156	A375	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.3900325943776507	[297]	[160,242,253,384]	-5	hSpCas9	negative selection	5821038
10368294	10368317	19	-	27260156	A375	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.1742822156550553	[701]	[860,1098,1205,594]	2	hSpCas9	negative selection	5821039
10368143	10368166	19	-	27260156	A375	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.6546247314131193	[525]	[289,446,395,428]	-7	hSpCas9	negative selection	5885286
10362340	10362363	19	+	27260156	A375	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.1594150409034464	[552]	[601,601,808,837]	2	hSpCas9	negative selection	5885287
10364699	10364722	19	-	27260156	A375	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.062020132985381615	[362]	[394,506,429,444]	0	hSpCas9	negative selection	5885288
10364715	10364738	19	+	27260156	COLO741	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.20663546491226747	[268]	[419,416,356]	4	hSpCas9	negative selection	5942288
10362352	10362375	19	-	27260156	COLO741	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	0.07095924708424461	[297]	[355,406,429]	1	hSpCas9	negative selection	5942289
10368294	10368317	19	-	27260156	COLO741	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.29980643637337256	[701]	[1428,987,932]	6	hSpCas9	negative selection	5942290
10368143	10368166	19	-	27260156	COLO741	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.15581198183259412	[525]	[622,693,500]	-3	hSpCas9	negative selection	6006537
10362340	10362363	19	+	27260156	COLO741	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.11393181431569208	[552]	[863,707,730]	2	hSpCas9	negative selection	6006538
10364699	10364722	19	-	27260156	COLO741	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.045895510080303736	[362]	[408,491,442]	-1	hSpCas9	negative selection	6006539
10364715	10364738	19	+	27260156	CAL120	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.06299296210234584	[268]	[233,271,439]	-1	hSpCas9	negative selection	6063539
10362352	10362375	19	-	27260156	CAL120	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.06799640958917796	[297]	[250,459,334]	-1	hSpCas9	negative selection	6063540
10368294	10368317	19	-	27260156	CAL120	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.3939050118724029	[701]	[1623,932,960]	6	hSpCas9	negative selection	6063541
10368143	10368166	19	-	27260156	CAL120	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	0.021237077641004937	[525]	[404,1080,470]	0	hSpCas9	negative selection	6127788
10362340	10362363	19	+	27260156	CAL120	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.1764380078820069	[552]	[976,905,484]	2	hSpCas9	negative selection	6127789
10364699	10364722	19	-	27260156	CAL120	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.16547135858415357	[362]	[608,417,507]	2	hSpCas9	negative selection	6127790
10364715	10364738	19	+	27260156	CADOES1	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.31598401319460595	[268]	[376,371,204,290]	5	hSpCas9	negative selection	6184790
10362352	10362375	19	-	27260156	CADOES1	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.43505018996944667	[297]	[309,138,155,214]	-6	hSpCas9	negative selection	6184791
10368294	10368317	19	-	27260156	CADOES1	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.2329012276008513	[701]	[696,922,571,881]	4	hSpCas9	negative selection	6184792
10368143	10368166	19	-	27260156	CADOES1	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.23523060182003336	[525]	[490,452,336,379]	-4	hSpCas9	negative selection	6249039
10362340	10362363	19	+	27260156	CADOES1	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.2876994633917188	[552]	[383,410,453,436]	-5	hSpCas9	negative selection	6249040
10364699	10364722	19	-	27260156	CADOES1	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.2399085287992232	[362]	[403,353,428,407]	4	hSpCas9	negative selection	6249041
10364715	10364738	19	+	27260156	EWS502	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.24960691335932816	[268]	[290,361,380,323]	4	hSpCas9	negative selection	6306041
10362352	10362375	19	-	27260156	EWS502	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.528832420165754	[297]	[287,158,218,200]	-7	hSpCas9	negative selection	6306042
10368294	10368317	19	-	27260156	EWS502	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.3692637828805607	[701]	[1009,936,947,935]	6	hSpCas9	negative selection	6306043
10368143	10368166	19	-	27260156	EWS502	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.13724579799319347	[525]	[399,532,636,464]	-2	hSpCas9	negative selection	6370290
10362340	10362363	19	+	27260156	EWS502	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.19610014298397846	[552]	[643,937,485,597]	3	hSpCas9	negative selection	6370291
10364699	10364722	19	-	27260156	EWS502	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.10366193398430368	[362]	[332,365,318,660]	1	hSpCas9	negative selection	6370292
10364715	10364738	19	+	27260156	EW8	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.2653580000504251	[268]	[240,331,246,227]	5	hSpCas9	negative selection	6427292
10362352	10362375	19	-	27260156	EW8	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.11983493553916147	[297]	[272,268,236,112]	-2	hSpCas9	negative selection	6427293
10368294	10368317	19	-	27260156	EW8	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.3097999153292096	[701]	[858,737,580,678]	5	hSpCas9	negative selection	6427294
10368143	10368166	19	-	27260156	EW8	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.48660263310808405	[525]	[283,263,210,469]	-7	hSpCas9	negative selection	6491541
10362340	10362363	19	+	27260156	EW8	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.018562220107908506	[552]	[451,587,455,318]	0	hSpCas9	negative selection	6491542
10364699	10364722	19	-	27260156	EW8	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.06057000837320242	[362]	[313,298,222,404]	1	hSpCas9	negative selection	6491543
10364715	10364738	19	+	27260156	CORL105	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.005476652095491308	[268]	[355,354,283,255]	0	hSpCas9	negative selection	6548543
10362352	10362375	19	-	27260156	CORL105	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.006948343102636034	[297]	[385,375,292,325]	0	hSpCas9	negative selection	6548544
10368294	10368317	19	-	27260156	CORL105	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.11408826945572326	[701]	[886,926,921,825]	2	hSpCas9	negative selection	6548545
10368143	10368166	19	-	27260156	CORL105	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.32201644517105216	[525]	[477,547,468,469]	-5	hSpCas9	negative selection	6612792
10362340	10362363	19	+	27260156	CORL105	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.020168248992589732	[552]	[630,662,758,518]	0	hSpCas9	negative selection	6612793
10364699	10364722	19	-	27260156	CORL105	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.09412868094751492	[362]	[504,367,379,340]	-2	hSpCas9	negative selection	6612794
10364715	10364738	19	+	27260156	HS294T	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.05319370344321017	[268]	[114,99,74,110]	0	hSpCas9	negative selection	6669794
10362352	10362375	19	-	27260156	HS294T	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.8605484832563505	[297]	[36,66,68,86]	-8	hSpCas9	negative selection	6669795
10368294	10368317	19	-	27260156	HS294T	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.04115104898976463	[701]	[222,258,382,252]	0	hSpCas9	negative selection	6669796
10368143	10368166	19	-	27260156	HS294T	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.10597602751262303	[525]	[164,191,208,191]	-1	hSpCas9	negative selection	6734043
10362340	10362363	19	+	27260156	HS294T	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.3902145868685155	[552]	[99,172,160,235]	-5	hSpCas9	negative selection	6734044
10364699	10364722	19	-	27260156	HS294T	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.400556283429726	[362]	[114,73,95,146]	-5	hSpCas9	negative selection	6734045
10364715	10364738	19	+	27260156	HCC44	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.15831129251405718	[268]	[302,239,612,259]	2	hSpCas9	negative selection	6791045
10362352	10362375	19	-	27260156	HCC44	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	0.14635488719083134	[297]	[448,350,374,325]	2	hSpCas9	negative selection	6791046
10368294	10368317	19	-	27260156	HCC44	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.4776598899891171	[701]	[1435,601,926,1505]	7	hSpCas9	negative selection	6791047
10368143	10368166	19	-	27260156	HCC44	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	0.007163283752491145	[525]	[655,677,666,397]	0	hSpCas9	negative selection	6855294
10362340	10362363	19	+	27260156	HCC44	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.21642244771287486	[552]	[839,644,785,663]	3	hSpCas9	negative selection	6855295
10364699	10364722	19	-	27260156	HCC44	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.12648996478809887	[362]	[403,326,506,297]	-2	hSpCas9	negative selection	6855296
10364715	10364738	19	+	27260156	G402	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.017765810032265295	[268]	[119,567,367,228]	0	hSpCas9	negative selection	6912296
10362352	10362375	19	-	27260156	G402	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	0.12348715965370438	[297]	[295,351,417,494]	1	hSpCas9	negative selection	6912297
10368294	10368317	19	-	27260156	G402	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.680446462501288	[701]	[1706,1289,1386,1155]	8	hSpCas9	negative selection	6912298
10368143	10368166	19	-	27260156	G402	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	0.2308391843045432	[525]	[593,914,558,919]	3	hSpCas9	negative selection	6976545
10362340	10362363	19	+	27260156	G402	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.09180209451830298	[552]	[725,822,527,484]	-1	hSpCas9	negative selection	6976546
10364699	10364722	19	-	27260156	G402	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.08325995139757009	[362]	[679,254,343,419]	-1	hSpCas9	negative selection	6976547
10364715	10364738	19	+	27260156	L33	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.043016684594404886	[268]	[220,123,182,230]	-1	hSpCas9	negative selection	7033547
10362352	10362375	19	-	27260156	L33	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.2769734671499	[297]	[219,97,195,213]	-6	hSpCas9	negative selection	7033548
10368294	10368317	19	-	27260156	L33	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	-0.01518498455398376	[701]	[581,287,380,887]	0	hSpCas9	negative selection	7033549
10368143	10368166	19	-	27260156	L33	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	0.29142097465527955	[525]	[862,235,340,587]	6	hSpCas9	negative selection	7097796
10362340	10362363	19	+	27260156	L33	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.11475773734078284	[552]	[677,242,339,580]	2	hSpCas9	negative selection	7097797
10364699	10364722	19	-	27260156	L33	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.3889217434113425	[362]	[247,112,190,281]	-7	hSpCas9	negative selection	7097798
10364715	10364738	19	+	27260156	K562	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.6906359373744273	[268]	[218,64,193,117]	-7	hSpCas9	negative selection	7154798
10362352	10362375	19	-	27260156	K562	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.7798381742004389	[297]	[355,52,28,184]	-7	hSpCas9	negative selection	7154799
10368294	10368317	19	-	27260156	K562	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.1741760031237375	[701]	[753,610,956,508]	2	hSpCas9	negative selection	7154800
10368143	10368166	19	-	27260156	K562	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.6934809059195766	[525]	[333,318,342,175]	-7	hSpCas9	negative selection	7219047
10362340	10362363	19	+	27260156	K562	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.6342187045446175	[552]	[972,864,605,636]	7	hSpCas9	negative selection	7219048
10364699	10364722	19	-	27260156	K562	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.2864209732737676	[362]	[559,393,400,245]	3	hSpCas9	negative selection	7219049
10364715	10364738	19	+	27260156	HT29	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.17653631186243457	[268]	[243,337,356,224]	-4	hSpCas9	negative selection	7276049
10362352	10362375	19	-	27260156	HT29	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.2965027901912466	[297]	[264,421,201,296]	-5	hSpCas9	negative selection	7276050
10368294	10368317	19	-	27260156	HT29	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.1360418930334899	[701]	[1070,999,941,767]	2	hSpCas9	negative selection	7276051
10368143	10368166	19	-	27260156	HT29	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.222222723924231	[525]	[706,519,536,446]	-4	hSpCas9	negative selection	7340298
10362340	10362363	19	+	27260156	HT29	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.10894233082190624	[552]	[727,654,550,571]	-2	hSpCas9	negative selection	7340299
10364699	10364722	19	-	27260156	HT29	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.15120394042012159	[362]	[418,415,430,331]	-3	hSpCas9	negative selection	7340300
10364715	10364738	19	+	27260156	MHHES1	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.24264146826084332	[268]	[328,267,180,250]	-4	hSpCas9	negative selection	7397300
10362352	10362375	19	-	27260156	MHHES1	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.12673592332264183	[297]	[262,336,463,185]	-2	hSpCas9	negative selection	7397301
10368294	10368317	19	-	27260156	MHHES1	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.3399009433716761	[701]	[1027,1199,1033,790]	6	hSpCas9	negative selection	7397302
10368143	10368166	19	-	27260156	MHHES1	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.21314895039236845	[525]	[511,505,604,428]	-4	hSpCas9	negative selection	7461549
10362340	10362363	19	+	27260156	MHHES1	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.2573717332207778	[552]	[790,892,794,548]	5	hSpCas9	negative selection	7461550
10364699	10364722	19	-	27260156	MHHES1	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.10614691716575342	[362]	[514,496,448,329]	2	hSpCas9	negative selection	7461551
10364715	10364738	19	+	27260156	MEWO	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.21336532388511664	[268]	[324,231,324]	4	hSpCas9	negative selection	7518551
10362352	10362375	19	-	27260156	MEWO	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.08509997247024337	[297]	[268,184,335]	-2	hSpCas9	negative selection	7518552
10368294	10368317	19	-	27260156	MEWO	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.029284728161173113	[701]	[821,659,557]	0	hSpCas9	negative selection	7518553
10368143	10368166	19	-	27260156	MEWO	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.40959107007006756	[525]	[425,390,304]	-7	hSpCas9	negative selection	7582800
10362340	10362363	19	+	27260156	MEWO	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.24456272736214316	[552]	[738,634,488]	5	hSpCas9	negative selection	7582801
10364699	10364722	19	-	27260156	MEWO	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.04789570522787384	[362]	[318,335,391]	1	hSpCas9	negative selection	7582802
10364715	10364738	19	+	27260156	LNCAPCLONEFGC	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.10834906658256582	[268]	[116,259,386,307]	1	hSpCas9	negative selection	7639802
10362352	10362375	19	-	27260156	LNCAPCLONEFGC	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.6699524553767894	[297]	[135,116,319,131]	-7	hSpCas9	negative selection	7639803
10368294	10368317	19	-	27260156	LNCAPCLONEFGC	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.13209577401451789	[701]	[624,583,939,682]	2	hSpCas9	negative selection	7639804
10368143	10368166	19	-	27260156	LNCAPCLONEFGC	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.3153257895809062	[525]	[390,279,462,415]	-5	hSpCas9	negative selection	7704051
10362340	10362363	19	+	27260156	LNCAPCLONEFGC	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.10895552057226301	[552]	[489,558,645,480]	1	hSpCas9	negative selection	7704052
10364699	10364722	19	-	27260156	LNCAPCLONEFGC	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.054172301281348534	[362]	[384,287,414,290]	0	hSpCas9	negative selection	7704053
10364715	10364738	19	+	27260156	PANC0327	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.1951072626922633	[268]	[117,330,304,319]	3	hSpCas9	negative selection	7761053
10362352	10362375	19	-	27260156	PANC0327	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.24769163781367853	[297]	[210,119,231,340]	-4	hSpCas9	negative selection	7761054
10368294	10368317	19	-	27260156	PANC0327	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.37879262173852946	[701]	[1193,676,854,565]	5	hSpCas9	negative selection	7761055
10368143	10368166	19	-	27260156	PANC0327	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.033586157965093594	[525]	[428,500,510,376]	0	hSpCas9	negative selection	7825302
10362340	10362363	19	+	27260156	PANC0327	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.13254438054220977	[552]	[390,685,649,395]	2	hSpCas9	negative selection	7825303
10364699	10364722	19	-	27260156	PANC0327	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.2900980280046058	[362]	[605,212,506,291]	4	hSpCas9	negative selection	7825304
10364715	10364738	19	+	27260156	NCIH2009	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.20520739911676333	[268]	[474,265,266]	-3	hSpCas9	negative selection	7882304
10362352	10362375	19	-	27260156	NCIH2009	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-1.0450436110839791	[297]	[322,198,106]	-8	hSpCas9	negative selection	7882305
10368294	10368317	19	-	27260156	NCIH2009	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.39669333201894164	[701]	[1511,1020,1386]	5	hSpCas9	negative selection	7882306
10368143	10368166	19	-	27260156	NCIH2009	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.011550600441503994	[525]	[697,880,597]	0	hSpCas9	negative selection	7946553
10362340	10362363	19	+	27260156	NCIH2009	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.5211004288257369	[552]	[1621,1099,703]	7	hSpCas9	negative selection	7946554
10364699	10364722	19	-	27260156	NCIH2009	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.21615432756257874	[362]	[507,500,312]	-3	hSpCas9	negative selection	7946555
10364715	10364738	19	+	27260156	NCIH1373	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.27792371967735763	[268]	[339,423,254,114]	2	hSpCas9	negative selection	8003555
10362352	10362375	19	-	27260156	NCIH1373	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.707193201176265	[297]	[229,369,99,25]	-6	hSpCas9	negative selection	8003556
10368294	10368317	19	-	27260156	NCIH1373	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.40906543210169377	[701]	[1042,753,1214,314]	4	hSpCas9	negative selection	8003557
10368143	10368166	19	-	27260156	NCIH1373	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.8479300250760928	[525]	[491,289,300,65]	-7	hSpCas9	negative selection	8067804
10362340	10362363	19	+	27260156	NCIH1373	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.40298714163498206	[552]	[1420,774,556,160]	4	hSpCas9	negative selection	8067805
10364699	10364722	19	-	27260156	NCIH1373	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.266207814219278	[362]	[285,392,410,62]	-3	hSpCas9	negative selection	8067806
10364715	10364738	19	+	27260156	PATU8902	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.8944696821800783	[268]	[623,490,977,602]	8	hSpCas9	negative selection	8124806
10362352	10362375	19	-	27260156	PATU8902	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	0.21102828034874943	[297]	[359,490,419,688]	2	hSpCas9	negative selection	8124807
10368294	10368317	19	-	27260156	PATU8902	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.9780614487682306	[701]	[1852,1707,1889,2289]	9	hSpCas9	negative selection	8124808
10368143	10368166	19	-	27260156	PATU8902	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	0.3685243104767825	[525]	[1376,1148,396,995]	4	hSpCas9	negative selection	8189055
10362340	10362363	19	+	27260156	PATU8902	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.5080182761740074	[552]	[1319,851,566,1857]	5	hSpCas9	negative selection	8189056
10364699	10364722	19	-	27260156	PATU8902	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	1.1924160933735044	[362]	[2091,852,956,692]	9	hSpCas9	negative selection	8189057
10364715	10364738	19	+	27260156	PANC1	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	1.366776360202174	[268]	[152,2285,157,196]	9	hSpCas9	negative selection	8246057
10362352	10362375	19	-	27260156	PANC1	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.4136539743365798	[297]	[119,205,236,204]	-6	hSpCas9	negative selection	8246058
10368294	10368317	19	-	27260156	PANC1	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.2908056402150502	[701]	[613,1006,773,620]	5	hSpCas9	negative selection	8246059
10368143	10368166	19	-	27260156	PANC1	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.5284082971569593	[525]	[303,514,287,200]	-7	hSpCas9	negative selection	8310306
10362340	10362363	19	+	27260156	PANC1	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.17428910595780037	[552]	[563,380,329,393]	-3	hSpCas9	negative selection	8310307
10364699	10364722	19	-	27260156	PANC1	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.1755822257099155	[362]	[220,375,339,197]	-3	hSpCas9	negative selection	8310308
10364715	10364738	19	+	27260156	PANC0813	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.2524279830682977	[268]	[504,382,281,347]	4	hSpCas9	negative selection	8367308
10362352	10362375	19	-	27260156	PANC0813	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.8826706000741177	[297]	[292,210,141,125]	-8	hSpCas9	negative selection	8367309
10368294	10368317	19	-	27260156	PANC0813	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.07495188272371356	[701]	[1276,574,782,874]	1	hSpCas9	negative selection	8367310
10368143	10368166	19	-	27260156	PANC0813	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.07950911686736148	[525]	[759,615,611,377]	-1	hSpCas9	negative selection	8431557
10362340	10362363	19	+	27260156	PANC0813	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.25529349696459813	[552]	[743,598,1027,729]	4	hSpCas9	negative selection	8431558
10364699	10364722	19	-	27260156	PANC0813	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.19291046185336064	[362]	[369,382,430,310]	-3	hSpCas9	negative selection	8431559
10364715	10364738	19	+	27260156	RDES	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.0677683917695735	[268]	[180,519,341,244]	1	hSpCas9	negative selection	8488559
10362352	10362375	19	-	27260156	RDES	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.006934033015384977	[297]	[252,293,444,398]	0	hSpCas9	negative selection	8488560
10368294	10368317	19	-	27260156	RDES	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.39270635371029017	[701]	[824,1062,1026,1392]	6	hSpCas9	negative selection	8488561
10368143	10368166	19	-	27260156	RDES	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.42141463309038796	[525]	[401,437,474,496]	-6	hSpCas9	negative selection	8552808
10362340	10362363	19	+	27260156	RDES	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.2707215954894442	[552]	[585,708,728,1119]	4	hSpCas9	negative selection	8552809
10364699	10364722	19	-	27260156	RDES	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.15869073684255297	[362]	[350,454,533,551]	2	hSpCas9	negative selection	8552810
10364715	10364738	19	+	27260156	PC3	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.22482591000608831	[268]	[132,186,352,320]	-5	hSpCas9	negative selection	8609810
10362352	10362375	19	-	27260156	PC3	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.561268804103413	[297]	[120,204,384,180]	-8	hSpCas9	negative selection	8609811
10368294	10368317	19	-	27260156	PC3	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.11094916354513351	[701]	[388,837,1499,675]	2	hSpCas9	negative selection	8609812
10368143	10368166	19	-	27260156	PC3	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.38428675403771645	[525]	[190,350,700,551]	-7	hSpCas9	negative selection	8674059
10362340	10362363	19	+	27260156	PC3	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.1816996401378641	[552]	[419,401,731,454]	-4	hSpCas9	negative selection	8674060
10364699	10364722	19	-	27260156	PC3	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.1406457337009412	[362]	[183,320,540,386]	-3	hSpCas9	negative selection	8674061
10364715	10364738	19	+	27260156	PATU8988T	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.2911279522306771	[268]	[251,212,126,262]	-5	hSpCas9	negative selection	8731061
10362352	10362375	19	-	27260156	PATU8988T	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.47434854800987314	[297]	[168,260,198,204]	-6	hSpCas9	negative selection	8731062
10368294	10368317	19	-	27260156	PATU8988T	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.03693446863050531	[701]	[704,767,586,734]	0	hSpCas9	negative selection	8731063
10368143	10368166	19	-	27260156	PATU8988T	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.32293333518590156	[525]	[410,378,273,573]	-5	hSpCas9	negative selection	8795310
10362340	10362363	19	+	27260156	PATU8988T	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.11197132400074972	[552]	[476,581,528,388]	-2	hSpCas9	negative selection	8795311
10364699	10364722	19	-	27260156	PATU8988T	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.05775300529668398	[362]	[484,222,330,294]	-1	hSpCas9	negative selection	8795312
10364715	10364738	19	+	27260156	T47D	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.05355407041604088	[268]	[316,311,338,333]	1	hSpCas9	negative selection	8852312
10362352	10362375	19	-	27260156	T47D	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.07093910823204064	[297]	[306,379,299,330]	-1	hSpCas9	negative selection	8852313
10368294	10368317	19	-	27260156	T47D	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.3128434760946287	[701]	[990,1056,1070,936]	6	hSpCas9	negative selection	8852314
10368143	10368166	19	-	27260156	T47D	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.448861556887773	[525]	[410,374,423,596]	-7	hSpCas9	negative selection	8916561
10362340	10362363	19	+	27260156	T47D	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.06525595743172655	[552]	[681,600,588,591]	-1	hSpCas9	negative selection	8916562
10364699	10364722	19	-	27260156	T47D	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.11647764967132729	[362]	[410,535,365,516]	2	hSpCas9	negative selection	8916563
10364715	10364738	19	+	27260156	SU8686	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.2164055804413827	[268]	[308,282,373,269]	3	hSpCas9	negative selection	8973563
10362352	10362375	19	-	27260156	SU8686	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.43300575202460323	[297]	[170,255,213,235]	-6	hSpCas9	negative selection	8973564
10368294	10368317	19	-	27260156	SU8686	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.38087125942805056	[701]	[968,862,882,899]	6	hSpCas9	negative selection	8973565
10368143	10368166	19	-	27260156	SU8686	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.21746864206320843	[525]	[380,295,639,517]	-4	hSpCas9	negative selection	9037812
10362340	10362363	19	+	27260156	SU8686	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.20468009046611682	[552]	[613,645,479,806]	3	hSpCas9	negative selection	9037813
10364699	10364722	19	-	27260156	SU8686	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.003818504477640705	[362]	[291,304,400,477]	0	hSpCas9	negative selection	9037814
10364715	10364738	19	+	27260156	SKES1	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.00834836323042043	[268]	[380,376,208,152]	0	hSpCas9	negative selection	9094814
10362352	10362375	19	-	27260156	SKES1	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.0677012909924729	[297]	[370,270,341,170]	-1	hSpCas9	negative selection	9094815
10368294	10368317	19	-	27260156	SKES1	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.1898810055817879	[701]	[865,941,580,823]	4	hSpCas9	negative selection	9094816
10368143	10368166	19	-	27260156	SKES1	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.3127427335550663	[525]	[477,398,457,361]	-6	hSpCas9	negative selection	9159063
10362340	10362363	19	+	27260156	SKES1	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.04281101004651813	[552]	[481,758,612,438]	0	hSpCas9	negative selection	9159064
10364699	10364722	19	-	27260156	SKES1	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.13812986100656816	[362]	[446,401,375,374]	3	hSpCas9	negative selection	9159065
10364715	10364738	19	+	27260156	TOV112D	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.29709131239187636	[268]	[364,341,250,369]	5	hSpCas9	negative selection	9216065
10362352	10362375	19	-	27260156	TOV112D	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.17248108441329246	[297]	[203,194,351,284]	-3	hSpCas9	negative selection	9216066
10368294	10368317	19	-	27260156	TOV112D	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.08604873939069468	[701]	[707,719,862,684]	1	hSpCas9	negative selection	9216067
10368143	10368166	19	-	27260156	TOV112D	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.28232073117266815	[525]	[374,610,319,463]	-5	hSpCas9	negative selection	9280314
10362340	10362363	19	+	27260156	TOV112D	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.04411232662839279	[552]	[490,550,410,689]	-1	hSpCas9	negative selection	9280315
10364699	10364722	19	-	27260156	TOV112D	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.007496868992889316	[362]	[348,403,447,270]	0	hSpCas9	negative selection	9280316
10364715	10364738	19	+	27260156	TC71	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.10134269509923244	[268]	[219,301,336,383]	2	hSpCas9	negative selection	9337316
10362352	10362375	19	-	27260156	TC71	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.15537932128407883	[297]	[251,293,265,339]	-4	hSpCas9	negative selection	9337317
10368294	10368317	19	-	27260156	TC71	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.1577250681606588	[701]	[852,847,728,936]	4	hSpCas9	negative selection	9337318
10368143	10368166	19	-	27260156	TC71	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	0.10500845982486068	[525]	[463,695,580,693]	2	hSpCas9	negative selection	9401565
10362340	10362363	19	+	27260156	TC71	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	-0.06011300523375232	[552]	[514,626,451,692]	-1	hSpCas9	negative selection	9401566
10364699	10364722	19	-	27260156	TC71	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	-0.0395769876293407	[362]	[388,390,403,325]	-1	hSpCas9	negative selection	9401567
10364715	10364738	19	+	27260156	TC32	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.1724644056085466	[268]	[163,131,344,312]	-3	hSpCas9	negative selection	9458567
10362352	10362375	19	-	27260156	TC32	viability	GCCGGTCCTTCCCCAGCGTTCGG	TYK2	ENSG00000105397	-0.38130121769865066	[297]	[138,217,253,252]	-6	hSpCas9	negative selection	9458568
10368294	10368317	19	-	27260156	TC32	viability	TGATGCTATATTTCCGCATAAGG	TYK2	ENSG00000105397	0.20759961916569347	[701]	[614,611,1035,867]	4	hSpCas9	negative selection	9458569
10368143	10368166	19	-	27260156	TC32	viability	GAACCGGCTGTGTACCGTTGTGG	TYK2	ENSG00000105397	-0.3543943574836008	[525]	[386,255,460,487]	-6	hSpCas9	negative selection	9522816
10362340	10362363	19	+	27260156	TC32	viability	AGCCCCAAGTTCCCGAACGCTGG	TYK2	ENSG00000105397	0.06804790001064817	[552]	[509,410,785,535]	1	hSpCas9	negative selection	9522817
10364699	10364722	19	-	27260156	TC32	viability	GGACGGCTATTTCCGCCTGACGG	TYK2	ENSG00000105397	0.4461945303920238	[362]	[445,451,567,382]	7	hSpCas9	negative selection	9522818
10364638	10364661	19	+	27869803	HPAFII	viability after 27 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.11626506525109703	[770]	[458,422,NaN]	0	hSpCas9	negative selection	9565350
10364865	10364888	19	-	27869803	HPAFII	viability after 27 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.8580343147262437	[310]	[357,244,NaN]	7	hSpCas9	negative selection	9565351
10365861	10365884	19	+	27869803	HPAFII	viability after 27 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-0.46860873026977456	[211]	[67,90,NaN]	-3	hSpCas9	negative selection	9565352
10366493	10366516	19	+	27869803	HPAFII	viability after 27 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	1.2668149784636624	[570]	[627,800,NaN]	9	hSpCas9	negative selection	9565353
10368159	10368182	19	-	27869803	HPAFII	viability after 27 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.8889530995403867	[670]	[409,855,NaN]	7	hSpCas9	negative selection	9565354
10378260	10378283	19	+	27869803	HPAFII	viability after 27 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.10875936600947667	[177]	[89,109,NaN]	0	hSpCas9	negative selection	9565355
10364638	10364661	19	+	27869803	HPAFII	viability after 15 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	-0.06112960983034865	[770]	[1215,531,NaN]	0	hSpCas9	negative selection	9647799
10364865	10364888	19	-	27869803	HPAFII	viability after 15 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.2830310010656411	[310]	[447,380,NaN]	3	hSpCas9	negative selection	9647800
10365861	10365884	19	+	27869803	HPAFII	viability after 15 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-0.6774165267908997	[211]	[139,143,NaN]	-6	hSpCas9	negative selection	9647801
10366493	10366516	19	+	27869803	HPAFII	viability after 15 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.6518933071551647	[570]	[1319,742,NaN]	7	hSpCas9	negative selection	9647802
10368159	10368182	19	-	27869803	HPAFII	viability after 15 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.4943858934199239	[670]	[915,1077,NaN]	5	hSpCas9	negative selection	9647803
10378260	10378283	19	+	27869803	HPAFII	viability after 15 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.16391353417327625	[177]	[246,193,NaN]	2	hSpCas9	negative selection	9647804
10364638	10364661	19	+	27869803	ASPC1	viability after 36 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.39366715865047497	[1723]	[733,384,1143]	4	hSpCas9	negative selection	9730248
10364865	10364888	19	-	27869803	ASPC1	viability after 36 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	-0.2064901151609857	[739]	[493,175,69]	-2	hSpCas9	negative selection	9730249
10365861	10365884	19	+	27869803	ASPC1	viability after 36 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-0.8077804021443017	[467]	[198,114,0]	-7	hSpCas9	negative selection	9730250
10366493	10366516	19	+	27869803	ASPC1	viability after 36 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.4474533489087966	[1403]	[362,678,866]	4	hSpCas9	negative selection	9730251
10368159	10368182	19	-	27869803	ASPC1	viability after 36 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.512569217500167	[1645]	[914,698,839]	5	hSpCas9	negative selection	9730252
10378260	10378283	19	+	27869803	ASPC1	viability after 36 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.15958005547562937	[409]	[136,207,135]	1	hSpCas9	negative selection	9730253
10364638	10364661	19	+	27869803	PATU8988S	viability after 35 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.7714249223597724	[1394]	[752,1165,NaN]	7	hSpCas9	negative selection	9812697
10364865	10364888	19	-	27869803	PATU8988S	viability after 35 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	-0.6080902639283077	[673]	[217,137,NaN]	-6	hSpCas9	negative selection	9812698
10365861	10365884	19	+	27869803	PATU8988S	viability after 35 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-0.3742358776317143	[385]	[93,145,NaN]	-4	hSpCas9	negative selection	9812699
10366493	10366516	19	+	27869803	PATU8988S	viability after 35 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	0.35326528704223636	[1219]	[706,547,NaN]	4	hSpCas9	negative selection	9812700
10368159	10368182	19	-	27869803	PATU8988S	viability after 35 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	0.03125272537034074	[1561]	[805,478,NaN]	0	hSpCas9	negative selection	9812701
10378260	10378283	19	+	27869803	PATU8988S	viability after 35 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	-1.5626928249340966	[406]	[50,59,NaN]	-8	hSpCas9	negative selection	9812702
10364638	10364661	19	+	27869803	PATU8988S	viability after 31 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.7946435748106488	[1394]	[641,1375,NaN]	8	hSpCas9	negative selection	9895146
10364865	10364888	19	-	27869803	PATU8988S	viability after 31 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	-0.5112570422775107	[673]	[188,187,NaN]	-5	hSpCas9	negative selection	9895147
10365861	10365884	19	+	27869803	PATU8988S	viability after 31 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-0.44746201184121537	[385]	[67,169,NaN]	-5	hSpCas9	negative selection	9895148
10366493	10366516	19	+	27869803	PATU8988S	viability after 31 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	-0.13108257898060494	[1219]	[518,348,NaN]	-1	hSpCas9	negative selection	9895149
10368159	10368182	19	-	27869803	PATU8988S	viability after 31 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	-0.1556852350574094	[1561]	[581,529,NaN]	-2	hSpCas9	negative selection	9895150
10378260	10378283	19	+	27869803	PATU8988S	viability after 31 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	-1.241451583658888	[406]	[65,71,NaN]	-8	hSpCas9	negative selection	9895151
10364638	10364661	19	+	27869803	HPAFII	viability after 35 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.16925386076016724	[770]	[238,663,NaN]	1	hSpCas9	negative selection	9977595
10364865	10364888	19	-	27869803	HPAFII	viability after 35 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	1.424037582876792	[310]	[429,413,NaN]	8	hSpCas9	negative selection	9977596
10365861	10365884	19	+	27869803	HPAFII	viability after 35 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-0.07620454162267024	[211]	[58,149,NaN]	0	hSpCas9	negative selection	9977597
10366493	10366516	19	+	27869803	HPAFII	viability after 35 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	1.4259398555705676	[570]	[628,942,NaN]	8	hSpCas9	negative selection	9977598
10368159	10368182	19	-	27869803	HPAFII	viability after 35 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	1.4041730162355501	[670]	[518,1326,NaN]	8	hSpCas9	negative selection	9977599
10378260	10378283	19	+	27869803	HPAFII	viability after 35 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.6110315622214959	[177]	[107,170,NaN]	4	hSpCas9	negative selection	9977600
10364638	10364661	19	+	27869803	HPAFII	viability after 31 days	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	-0.16105272215655053	[770]	[330,447,NaN]	-1	hSpCas9	negative selection	10060044
10364865	10364888	19	-	27869803	HPAFII	viability after 31 days	CTGTGTCAGCATCCACCGGCAGG	TYK2	ENSG00000105397	0.7915169140861749	[310]	[270,335,NaN]	6	hSpCas9	negative selection	10060045
10365861	10365884	19	+	27869803	HPAFII	viability after 31 days	TATGCCGGCGGAAGGAGCGCGGG	TYK2	ENSG00000105397	-0.9248132808136772	[211]	[32,94,NaN]	-5	hSpCas9	negative selection	10060046
10366493	10366516	19	+	27869803	HPAFII	viability after 31 days	CCAGGCTCTCATTCTTAAAGTGG	TYK2	ENSG00000105397	1.4235699128392236	[570]	[582,1160,NaN]	9	hSpCas9	negative selection	10060047
10368159	10368182	19	-	27869803	HPAFII	viability after 31 days	TGGCATGAATCCTCGGGAACCGG	TYK2	ENSG00000105397	1.08437665146213	[670]	[407,1223,NaN]	7	hSpCas9	negative selection	10060048
10378260	10378283	19	+	27869803	HPAFII	viability after 31 days	TGACTCACTGAAAGTGACCCAGG	TYK2	ENSG00000105397	0.9166050608970717	[177]	[178,198,NaN]	7	hSpCas9	negative selection	10060049
10365547	10365570	19	-	28162770	P31FUJ	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	1.1410536825168447	[190]	[494]	9	hSpCas9	negative selection	10259824
10356577	10356600	19	+	28162770	P31FUJ	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	0.1556299382822956	[300]	[393]	1	hSpCas9	negative selection	10259825
10378261	10378284	19	+	28162770	P31FUJ	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	0.3235911441100065	[186]	[274]	3	hSpCas9	negative selection	10259826
10366475	10366498	19	+	28162770	P31FUJ	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-0.7891955529387639	[299]	[203]	-6	hSpCas9	negative selection	10259827
10365534	10365557	19	-	28162770	P31FUJ	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-0.6056114683039249	[201]	[155]	-5	hSpCas9	negative selection	10259828
10364715	10364738	19	+	28162770	P31FUJ	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.39198627679996567	[130]	[201]	4	hSpCas9	negative selection	10259829
10364638	10364661	19	+	28162770	P31FUJ	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	1.4396231375571173	[15]	[50]	9	hSpCas9	negative selection	10259830
10362563	10362586	19	-	28162770	P31FUJ	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	0.5113588911560314	[279]	[468]	6	hSpCas9	negative selection	10259831
10357768	10357791	19	+	28162770	P31FUJ	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-0.11647808644714686	[130]	[141]	-1	hSpCas9	negative selection	10259832
10356653	10356676	19	+	28162770	P31FUJ	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	0.25262462275586306	[159]	[223]	2	hSpCas9	negative selection	10259833
10365547	10365570	19	-	28162770	TF1	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	NaN	[NaN]	[314]	1	hSpCas9	negative selection	10429190
10356577	10356600	19	+	28162770	TF1	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10429191
10378261	10378284	19	+	28162770	TF1	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10429192
10366475	10366498	19	+	28162770	TF1	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10429193
10365534	10365557	19	-	28162770	TF1	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10429194
10364715	10364738	19	+	28162770	TF1	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10429195
10364638	10364661	19	+	28162770	TF1	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10429196
10362563	10362586	19	-	28162770	TF1	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	NaN	[NaN]	[90]	1	hSpCas9	negative selection	10429197
10357768	10357791	19	+	28162770	TF1	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10429198
10356653	10356676	19	+	28162770	TF1	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10429199
10365547	10365570	19	-	28162770	SKM1	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	0.40932384808445016	[68]	[161]	4	hSpCas9	negative selection	10598556
10356577	10356600	19	+	28162770	SKM1	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	0.2829678615795371	[52]	[113]	2	hSpCas9	negative selection	10598557
10378261	10378284	19	+	28162770	SKM1	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	-0.4283378495357286	[50]	[66]	-4	hSpCas9	negative selection	10598558
10366475	10366498	19	+	28162770	SKM1	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-1.1278101275460908	[88]	[71]	-7	hSpCas9	negative selection	10598559
10365534	10365557	19	-	28162770	SKM1	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-0.12156197988091315	[63]	[103]	-1	hSpCas9	negative selection	10598560
10364715	10364738	19	+	28162770	SKM1	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.12539384147194044	[28]	[46]	-1	hSpCas9	negative selection	10598561
10364638	10364661	19	+	28162770	SKM1	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	-0.31950135749282227	[11]	[16]	-3	hSpCas9	negative selection	10598562
10362563	10362586	19	-	28162770	SKM1	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	0.3364276645824773	[55]	[124]	3	hSpCas9	negative selection	10598563
10357768	10357791	19	+	28162770	SKM1	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-1.0783414512817913	[42]	[35]	-7	hSpCas9	negative selection	10598564
10356653	10356676	19	+	28162770	SKM1	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	-0.17249894510613875	[50]	[79]	-1	hSpCas9	negative selection	10598565
10365547	10365570	19	-	28162770	SKM1	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	0.40932384808445016	[68]	[161]	4	hSpCas9	negative selection	10767922
10356577	10356600	19	+	28162770	SKM1	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	0.2829678615795371	[52]	[113]	2	hSpCas9	negative selection	10767923
10378261	10378284	19	+	28162770	SKM1	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	-0.4283378495357286	[50]	[66]	-4	hSpCas9	negative selection	10767924
10366475	10366498	19	+	28162770	SKM1	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-1.1278101275460908	[88]	[71]	-7	hSpCas9	negative selection	10767925
10365534	10365557	19	-	28162770	SKM1	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-0.12156197988091315	[63]	[103]	-1	hSpCas9	negative selection	10767926
10364715	10364738	19	+	28162770	SKM1	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.12539384147194044	[28]	[46]	-1	hSpCas9	negative selection	10767927
10364638	10364661	19	+	28162770	SKM1	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	-0.31950135749282227	[11]	[16]	-3	hSpCas9	negative selection	10767928
10362563	10362586	19	-	28162770	SKM1	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	0.3364276645824773	[55]	[124]	3	hSpCas9	negative selection	10767929
10357768	10357791	19	+	28162770	SKM1	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-1.0783414512817913	[42]	[35]	-7	hSpCas9	negative selection	10767930
10356653	10356676	19	+	28162770	SKM1	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	-0.17249894510613875	[50]	[79]	-1	hSpCas9	negative selection	10767931
10365547	10365570	19	-	28162770	PL21	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	1.3500802414774777	[209]	[232]	9	hSpCas9	negative selection	10937288
10356577	10356600	19	+	28162770	PL21	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	0.6218717663421722	[214]	[143]	5	hSpCas9	negative selection	10937289
10378261	10378284	19	+	28162770	PL21	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	-0.47523818145405416	[213]	[66]	-3	hSpCas9	negative selection	10937290
10366475	10366498	19	+	28162770	PL21	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-0.5154523288843191	[334]	[101]	-4	hSpCas9	negative selection	10937291
10365534	10365557	19	-	28162770	PL21	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	0.19335044882668112	[212]	[105]	1	hSpCas9	negative selection	10937292
10364715	10364738	19	+	28162770	PL21	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.5368259796768862	[119]	[35]	-4	hSpCas9	negative selection	10937293
10364638	10364661	19	+	28162770	PL21	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	-0.07996830470341498	[16]	[6]	0	hSpCas9	negative selection	10937294
10362563	10362586	19	-	28162770	PL21	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	-0.31443355834043807	[179]	[62]	-2	hSpCas9	negative selection	10937295
10357768	10357791	19	+	28162770	PL21	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-0.8296077289047321	[146]	[35]	-5	hSpCas9	negative selection	10937296
10356653	10356676	19	+	28162770	PL21	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	-0.4975908163937859	[132]	[40]	-4	hSpCas9	negative selection	10937297
10365547	10365570	19	-	28162770	P31FUJ	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	1.1410536825168447	[190]	[494]	9	hSpCas9	negative selection	11106654
10356577	10356600	19	+	28162770	P31FUJ	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	0.1556299382822956	[300]	[393]	1	hSpCas9	negative selection	11106655
10378261	10378284	19	+	28162770	P31FUJ	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	0.3235911441100065	[186]	[274]	3	hSpCas9	negative selection	11106656
10366475	10366498	19	+	28162770	P31FUJ	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-0.7891955529387639	[299]	[203]	-6	hSpCas9	negative selection	11106657
10365534	10365557	19	-	28162770	P31FUJ	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-0.6056114683039249	[201]	[155]	-5	hSpCas9	negative selection	11106658
10364715	10364738	19	+	28162770	P31FUJ	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.39198627679996567	[130]	[201]	4	hSpCas9	negative selection	11106659
10364638	10364661	19	+	28162770	P31FUJ	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	1.4396231375571173	[15]	[50]	9	hSpCas9	negative selection	11106660
10362563	10362586	19	-	28162770	P31FUJ	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	0.5113588911560314	[279]	[468]	6	hSpCas9	negative selection	11106661
10357768	10357791	19	+	28162770	P31FUJ	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-0.11647808644714686	[130]	[141]	-1	hSpCas9	negative selection	11106662
10356653	10356676	19	+	28162770	P31FUJ	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	0.25262462275586306	[159]	[223]	2	hSpCas9	negative selection	11106663
10365547	10365570	19	-	28162770	OCIAML5	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	1.107291444638657	[125]	[489]	8	hSpCas9	negative selection	11276020
10356577	10356600	19	+	28162770	OCIAML5	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	-0.16219609443309202	[136]	[220]	-1	hSpCas9	negative selection	11276021
10378261	10378284	19	+	28162770	OCIAML5	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	-0.477139284959306	[154]	[200]	-3	hSpCas9	negative selection	11276022
10366475	10366498	19	+	28162770	OCIAML5	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-1.7462719068414003	[183]	[98]	-7	hSpCas9	negative selection	11276023
10365534	10365557	19	-	28162770	OCIAML5	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-0.36280448656342623	[160]	[225]	-3	hSpCas9	negative selection	11276024
10364715	10364738	19	+	28162770	OCIAML5	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.6745283853118095	[83]	[94]	-4	hSpCas9	negative selection	11276025
10364638	10364661	19	+	28162770	OCIAML5	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.08081923327746576	[10]	[20]	0	hSpCas9	negative selection	11276026
10362563	10362586	19	-	28162770	OCIAML5	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	0.5671587253782805	[85]	[229]	5	hSpCas9	negative selection	11276027
10357768	10357791	19	+	28162770	OCIAML5	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-3.09668893958391	[108]	[22]	-9	hSpCas9	negative selection	11276028
10356653	10356676	19	+	28162770	OCIAML5	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	-0.8815103487564788	[98]	[96]	-5	hSpCas9	negative selection	11276029
10365547	10365570	19	-	28162770	EOL1	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	0.8297913205537428	[408]	[382]	7	hSpCas9	negative selection	11445386
10356577	10356600	19	+	28162770	EOL1	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	0.682526543485154	[258]	[218]	6	hSpCas9	negative selection	11445387
10378261	10378284	19	+	28162770	EOL1	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	-0.5155807086711397	[463]	[170]	-4	hSpCas9	negative selection	11445388
10366475	10366498	19	+	28162770	EOL1	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-1.548868076502464	[621]	[111]	-7	hSpCas9	negative selection	11445389
10365534	10365557	19	-	28162770	EOL1	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-0.42908918304416593	[436]	[170]	-3	hSpCas9	negative selection	11445390
10364715	10364738	19	+	28162770	EOL1	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.7386812262592006	[181]	[159]	6	hSpCas9	negative selection	11445391
10364638	10364661	19	+	28162770	EOL1	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	3.1633346311576513	[24]	[117]	9	hSpCas9	negative selection	11445392
10362563	10362586	19	-	28162770	EOL1	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	0.055792304848787194	[251]	[137]	0	hSpCas9	negative selection	11445393
10357768	10357791	19	+	28162770	EOL1	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-0.3467542502468599	[139]	[57]	-3	hSpCas9	negative selection	11445394
10356653	10356676	19	+	28162770	EOL1	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	0.6449736895868095	[192]	[158]	6	hSpCas9	negative selection	11445395
10365547	10365570	19	-	28162770	MOLM13	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	0.34337483979221295	[386]	[354]	2	hSpCas9	negative selection	11614752
10356577	10356600	19	+	28162770	MOLM13	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	-0.9368651444724041	[232]	[87]	-5	hSpCas9	negative selection	11614753
10378261	10378284	19	+	28162770	MOLM13	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	0.3237182778579449	[346]	[313]	2	hSpCas9	negative selection	11614754
10366475	10366498	19	+	28162770	MOLM13	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-1.6818577379601032	[425]	[95]	-7	hSpCas9	negative selection	11614755
10365534	10365557	19	-	28162770	MOLM13	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-0.46547342542513076	[274]	[143]	-3	hSpCas9	negative selection	11614756
10364715	10364738	19	+	28162770	MOLM13	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.7027531146872118	[180]	[212]	5	hSpCas9	negative selection	11614757
10364638	10364661	19	+	28162770	MOLM13	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	-0.3580812186803719	[38]	[21]	-2	hSpCas9	negative selection	11614758
10362563	10362586	19	-	28162770	MOLM13	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	0.09941870072018624	[314]	[243]	0	hSpCas9	negative selection	11614759
10357768	10357791	19	+	28162770	MOLM13	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-1.2821323654470738	[147]	[43]	-6	hSpCas9	negative selection	11614760
10356653	10356676	19	+	28162770	MOLM13	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	-0.07900507834305803	[186]	[127]	0	hSpCas9	negative selection	11614761
10365547	10365570	19	-	28162770	HEL	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	1.47222244090398	[304]	[541]	9	hSpCas9	negative selection	11784118
10356577	10356600	19	+	28162770	HEL	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	-1.4025851585091333	[193]	[46]	-7	hSpCas9	negative selection	11784119
10378261	10378284	19	+	28162770	HEL	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	-0.4023490575281811	[259]	[125]	-3	hSpCas9	negative selection	11784120
10366475	10366498	19	+	28162770	HEL	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-1.4021154037839034	[391]	[94]	-7	hSpCas9	negative selection	11784121
10365534	10365557	19	-	28162770	HEL	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-0.18472778573309784	[306]	[172]	-1	hSpCas9	negative selection	11784122
10364715	10364738	19	+	28162770	HEL	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-0.579653589336091	[174]	[74]	-4	hSpCas9	negative selection	11784123
10364638	10364661	19	+	28162770	HEL	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	2.8062375642832365	[24]	[111]	9	hSpCas9	negative selection	11784124
10362563	10362586	19	-	28162770	HEL	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	-0.5547984006498154	[210]	[91]	-4	hSpCas9	negative selection	11784125
10357768	10357791	19	+	28162770	HEL	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-0.8901351575723451	[135]	[46]	-5	hSpCas9	negative selection	11784126
10356653	10356676	19	+	28162770	HEL	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	-1.2553815539804294	[163]	[43]	-6	hSpCas9	negative selection	11784127
10365547	10365570	19	-	28162770	MV411	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	1.905495432784796	[185]	[586]	9	hSpCas9	negative selection	11953484
10356577	10356600	19	+	28162770	MV411	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	-1.1055174397252117	[234]	[91]	-6	hSpCas9	negative selection	11953485
10378261	10378284	19	+	28162770	MV411	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	-0.2054681340865117	[192]	[140]	-1	hSpCas9	negative selection	11953486
10366475	10366498	19	+	28162770	MV411	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-1.0208525805025137	[329]	[136]	-6	hSpCas9	negative selection	11953487
10365534	10365557	19	-	28162770	MV411	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-1.4353722733365255	[243]	[75]	-7	hSpCas9	negative selection	11953488
10364715	10364738	19	+	28162770	MV411	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.32989971097474835	[84]	[89]	3	hSpCas9	negative selection	11953489
10364638	10364661	19	+	28162770	MV411	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.8324000515039311	[9]	[14]	7	hSpCas9	negative selection	11953490
10362563	10362586	19	-	28162770	MV411	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	-0.46038169772391446	[195]	[119]	-3	hSpCas9	negative selection	11953491
10357768	10357791	19	+	28162770	MV411	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-1.8258114312478633	[100]	[23]	-8	hSpCas9	negative selection	11953492
10356653	10356676	19	+	28162770	MV411	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	0.40241221075911615	[96]	[107]	3	hSpCas9	negative selection	11953493
10365547	10365570	19	-	28162770	MONOMAC1	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	0.901207246243154	[148]	[318]	8	hSpCas9	negative selection	12122850
10356577	10356600	19	+	28162770	MONOMAC1	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	0.1453553503875242	[111]	[141]	1	hSpCas9	negative selection	12122851
10378261	10378284	19	+	28162770	MONOMAC1	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	-0.18572153383171952	[126]	[127]	-2	hSpCas9	negative selection	12122852
10366475	10366498	19	+	28162770	MONOMAC1	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	0.16321936648690805	[207]	[266]	1	hSpCas9	negative selection	12122853
10365534	10365557	19	-	28162770	MONOMAC1	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	0.20631884717165477	[123]	[163]	2	hSpCas9	negative selection	12122854
10364715	10364738	19	+	28162770	MONOMAC1	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.2581577786912729	[61]	[84]	2	hSpCas9	negative selection	12122855
10364638	10364661	19	+	28162770	MONOMAC1	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	-2.656468465696851	[10]	[1]	-9	hSpCas9	negative selection	12122856
10362563	10362586	19	-	28162770	MONOMAC1	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	-0.19703684705955368	[136]	[136]	-2	hSpCas9	negative selection	12122857
10357768	10357791	19	+	28162770	MONOMAC1	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-0.5642458212477826	[88]	[68]	-5	hSpCas9	negative selection	12122858
10356653	10356676	19	+	28162770	MONOMAC1	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	-0.07920035676569548	[93]	[101]	0	hSpCas9	negative selection	12122859
10365547	10365570	19	-	28162770	OCIAML2	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	1.1679706390810682	[32]	[410]	9	hSpCas9	negative selection	12292216
10356577	10356600	19	+	28162770	OCIAML2	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	0.5099178120916661	[27]	[220]	5	hSpCas9	negative selection	12292217
10378261	10378284	19	+	28162770	OCIAML2	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	-0.36509541106980375	[55]	[240]	-3	hSpCas9	negative selection	12292218
10366475	10366498	19	+	28162770	OCIAML2	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-0.10224241926213884	[54]	[283]	-1	hSpCas9	negative selection	12292219
10365534	10365557	19	-	28162770	OCIAML2	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-0.4706298252421612	[47]	[191]	-4	hSpCas9	negative selection	12292220
10364715	10364738	19	+	28162770	OCIAML2	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	0.45828707669635604	[12]	[98]	4	hSpCas9	negative selection	12292221
10364638	10364661	19	+	28162770	OCIAML2	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	-0.6632749031845577	[1]	[6]	-5	hSpCas9	negative selection	12292222
10362563	10362586	19	-	28162770	OCIAML2	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	-0.07208044875188627	[32]	[173]	0	hSpCas9	negative selection	12292223
10357768	10357791	19	+	28162770	OCIAML2	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-0.47062982524216124	[16]	[67]	-4	hSpCas9	negative selection	12292224
10356653	10356676	19	+	28162770	OCIAML2	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	0.14646529641980405	[36]	[226]	1	hSpCas9	negative selection	12292225
10365547	10365570	19	-	28162770	OCIAML3	viability	GCACTGGTGGCATCCAGTGGTGG	TYK2	ENSG00000105397	0.5228561173667353	[79]	[346]	5	hSpCas9	negative selection	12461582
10356577	10356600	19	+	28162770	OCIAML3	viability	GCAGCCGGGTGAGGTCACGCAGG	TYK2	ENSG00000105397	-0.5620647478214089	[66]	[136]	-4	hSpCas9	negative selection	12461583
10378261	10378284	19	+	28162770	OCIAML3	viability	GACTCACTGAAAGTGACCCAGGG	TYK2	ENSG00000105397	-0.33943481323856545	[56]	[135]	-3	hSpCas9	negative selection	12461584
10366475	10366498	19	+	28162770	OCIAML3	viability	GGTGCAGAAAGGCCATGCCCAGG	TYK2	ENSG00000105397	-0.25664950486719484	[92]	[234]	-2	hSpCas9	negative selection	12461585
10365534	10365557	19	-	28162770	OCIAML3	viability	CCAGTGGTGGCCAGTAGAGGAGG	TYK2	ENSG00000105397	-0.8935679221830711	[79]	[129]	-6	hSpCas9	negative selection	12461586
10364715	10364738	19	+	28162770	OCIAML3	viability	GCCGTCCACCAGCGACACGAAGG	TYK2	ENSG00000105397	-1.1085808131539212	[34]	[48]	-7	hSpCas9	negative selection	12461587
10364638	10364661	19	+	28162770	OCIAML3	viability	CGGATGCTCATCACCAGCCGTGG	TYK2	ENSG00000105397	0.920565532505595	[6]	[39]	7	hSpCas9	negative selection	12461588
10362563	10362586	19	-	28162770	OCIAML3	viability	CTACCGCCTGATCCTCACAGTGG	TYK2	ENSG00000105397	-0.383972425507698	[66]	[154]	-3	hSpCas9	negative selection	12461589
10357768	10357791	19	+	28162770	OCIAML3	viability	GAGGGACTGCGGCTCTGCAGAGG	TYK2	ENSG00000105397	-0.8570420461579569	[32]	[54]	-6	hSpCas9	negative selection	12461590
10356653	10356676	19	+	28162770	OCIAML3	viability	GAGTGTGGCCAGCTGTGGGCAGG	TYK2	ENSG00000105397	0.36376412428653937	[25]	[100]	3	hSpCas9	negative selection	12461591