Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 9618
• Symbol: Traf4
• Description: TNF receptor associated factor 4

DataSource: http://genomecrispr.dkfz.de/#!/results/Traf4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
28744217	28744240	17	-	26472758	Jiyoye	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.0520804226833118	[109]	[85]	0	hSpCas9	negative selection	171395
28747917	28747940	17	-	26472758	Jiyoye	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.22568180931959414	[244]	[157]	-2	hSpCas9	negative selection	171396
28748082	28748105	17	-	26472758	Jiyoye	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	171397
28748620	28748643	17	-	26472758	Jiyoye	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-4.680287459744466	[101]	[2]	-9	hSpCas9	negative selection	171398
28744207	28744230	17	-	26472758	Jiyoye	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	0.22610982245836064	[194]	[171]	1	hSpCas9	negative selection	171399
28748311	28748334	17	+	26472758	Jiyoye	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	0.24305600174476688	[92]	[82]	1	hSpCas9	negative selection	171400
28748350	28748373	17	-	26472758	Jiyoye	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	4.407175381505873	[0]	[15]	9	hSpCas9	negative selection	171401
28744135	28744158	17	+	26472758	Jiyoye	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	4.655102894949458	[0]	[18]	9	hSpCas9	negative selection	171402
28747842	28747865	17	+	26472758	Jiyoye	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.917551346734162	[257]	[102]	-6	hSpCas9	negative selection	171403
28744217	28744240	17	-	26472758	KBM7	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.16523943168069	[503,403]	[306,175]	1	hSpCas9	negative selection	362513
28747917	28747940	17	-	26472758	KBM7	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.18041798834465428	[838,588]	[375,374]	1	hSpCas9	negative selection	362514
28748082	28748105	17	-	26472758	KBM7	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-1.6263983750458126	[113,82]	[17,11]	-8	hSpCas9	negative selection	362515
28748620	28748643	17	-	26472758	KBM7	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-0.7788160841258862	[296,179]	[34,89]	-6	hSpCas9	negative selection	362516
28744207	28744230	17	-	26472758	KBM7	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	-0.30887706377007423	[625,596]	[219,243]	-3	hSpCas9	negative selection	362517
28748311	28748334	17	+	26472758	KBM7	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.019072527914870685	[298,271]	[113,148]	0	hSpCas9	negative selection	362518
28748350	28748373	17	-	26472758	KBM7	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-0.223731938355757	[109,96]	[48,34]	-2	hSpCas9	negative selection	362519
28744135	28744158	17	+	26472758	KBM7	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	0.04307022536117033	[68,92]	[48,31]	0	hSpCas9	negative selection	362520
28747842	28747865	17	+	26472758	KBM7	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.11045495369052455	[567,447]	[178,255]	-1	hSpCas9	negative selection	362521
28744217	28744240	17	-	26472758	Raji	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.20318469734921518	[252]	[50]	-2	hSpCas9	negative selection	553631
28747917	28747940	17	-	26472758	Raji	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.27854555944261317	[506]	[96]	-2	hSpCas9	negative selection	553632
28748082	28748105	17	-	26472758	Raji	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-2.008093682046337	[51]	[2]	-8	hSpCas9	negative selection	553633
28748620	28748643	17	-	26472758	Raji	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-1.2304861033827843	[90]	[8]	-7	hSpCas9	negative selection	553634
28744207	28744230	17	-	26472758	Raji	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	-0.18438258900351062	[283]	[57]	-1	hSpCas9	negative selection	553635
28748311	28748334	17	+	26472758	Raji	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.0015508361795645437	[219]	[50]	0	hSpCas9	negative selection	553636
28748350	28748373	17	-	26472758	Raji	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-0.4472053163040379	[46]	[7]	-4	hSpCas9	negative selection	553637
28744135	28744158	17	+	26472758	Raji	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	0.04848984632003095	[49]	[11]	0	hSpCas9	negative selection	553638
28747842	28747865	17	+	26472758	Raji	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.4387631056055338	[212]	[66]	4	hSpCas9	negative selection	553639
28744217	28744240	17	-	26472758	K562	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.3403877861971688	[377]	[403]	2	hSpCas9	negative selection	744749
28747917	28747940	17	-	26472758	K562	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.16067193991966489	[726]	[685]	1	hSpCas9	negative selection	744750
28748082	28748105	17	-	26472758	K562	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-0.006389375834087385	[93]	[78]	0	hSpCas9	negative selection	744751
28748620	28748643	17	-	26472758	K562	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-1.6300503902496941	[109]	[29]	-7	hSpCas9	negative selection	744752
28744207	28744230	17	-	26472758	K562	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	1.1032112351530932	[428]	[777]	8	hSpCas9	negative selection	744753
28748311	28748334	17	+	26472758	K562	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	1.017224090775401	[325]	[556]	8	hSpCas9	negative selection	744754
28748350	28748373	17	-	26472758	K562	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	0.6594562269452906	[89]	[119]	5	hSpCas9	negative selection	744755
28744135	28744158	17	+	26472758	K562	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	0.10105455249526951	[73]	[66]	0	hSpCas9	negative selection	744756
28747842	28747865	17	+	26472758	K562	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.4470099180290814	[523]	[602]	3	hSpCas9	negative selection	744757
28744111	28744134	17	-	26627737	DLD1	viability	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	0.18327454546127142	[1067]	[418,532,216]	1	hSpCas9	negative selection	796732
28744116	28744139	17	-	26627737	DLD1	viability	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.9775481309287433	[138]	[85,121,54]	8	hSpCas9	negative selection	796733
28747891	28747914	17	+	26627737	DLD1	viability	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.5498785538687363	[932]	[510,472,315]	5	hSpCas9	negative selection	796734
28747917	28747940	17	-	26627737	DLD1	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.6637100826977944	[546]	[74,215,46]	-6	hSpCas9	negative selection	796735
28748650	28748673	17	-	26627737	DLD1	viability	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	0.29298411976630356	[585]	[213,416,73]	3	hSpCas9	negative selection	796736
28749118	28749141	17	+	26627737	DLD1	viability	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-0.09432389852628129	[392]	[186,121,46]	-1	hSpCas9	negative selection	796737
28744111	28744134	17	-	26627737	GBM cells	viability after 5 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.11645043476649375	[471]	[224,241]	-2	hSpCas9	negative selection	879047
28744116	28744139	17	-	26627737	GBM cells	viability after 5 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.5306074259518327	[161]	[117,132]	7	hSpCas9	negative selection	879048
28747891	28747914	17	+	26627737	GBM cells	viability after 5 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.2457428180616883	[470]	[276,321]	4	hSpCas9	negative selection	879049
28747917	28747940	17	-	26627737	GBM cells	viability after 5 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-1.3398729847014312	[235]	[56,42]	-9	hSpCas9	negative selection	879050
28748650	28748673	17	-	26627737	GBM cells	viability after 5 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	0.3221253056102297	[219]	[157,136]	5	hSpCas9	negative selection	879051
28749118	28749141	17	+	26627737	GBM cells	viability after 5 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-0.5008891106979981	[156]	[61,56]	-7	hSpCas9	negative selection	879052
28744111	28744134	17	-	26627737	GBM cells	viability after 13 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.10665847080959467	[471]	[276,205]	-1	hSpCas9	negative selection	961362
28744116	28744139	17	-	26627737	GBM cells	viability after 13 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.36908196977494256	[161]	[123,104]	5	hSpCas9	negative selection	961363
28747891	28747914	17	+	26627737	GBM cells	viability after 13 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.2634048251382244	[470]	[346,273]	3	hSpCas9	negative selection	961364
28747917	28747940	17	-	26627737	GBM cells	viability after 13 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.8094081173432062	[235]	[66,77]	-7	hSpCas9	negative selection	961365
28748650	28748673	17	-	26627737	GBM cells	viability after 13 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	0.3993451266708954	[219]	[200,121]	5	hSpCas9	negative selection	961366
28749118	28749141	17	+	26627737	GBM cells	viability after 13 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-1.0118892890300435	[156]	[44,39]	-8	hSpCas9	negative selection	961367
28744111	28744134	17	-	26627737	GBM cells	viability after 21 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	0.3545556742413808	[471]	[330,324]	3	hSpCas9	negative selection	1043677
28744116	28744139	17	-	26627737	GBM cells	viability after 21 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	1.212101261860268	[161]	[217,190]	9	hSpCas9	negative selection	1043678
28747891	28747914	17	+	26627737	GBM cells	viability after 21 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.3184143751695674	[470]	[328,309]	3	hSpCas9	negative selection	1043679
28747917	28747940	17	-	26627737	GBM cells	viability after 21 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.13423882650398172	[235]	[120,112]	-1	hSpCas9	negative selection	1043680
28748650	28748673	17	-	26627737	GBM cells	viability after 21 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	1.0022868396004194	[219]	[252,226]	8	hSpCas9	negative selection	1043681
28749118	28749141	17	+	26627737	GBM cells	viability after 21 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-1.4279765140239236	[156]	[26,35]	-8	hSpCas9	negative selection	1043682
28744111	28744134	17	-	26627737	RPE1	viability after 9 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	0.12313126349351045	[2087]	[645,796]	0	hSpCas9	negative selection	1125992
28744116	28744139	17	-	26627737	RPE1	viability after 9 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.10119348378275458	[878]	[261,337]	0	hSpCas9	negative selection	1125993
28747891	28747914	17	+	26627737	RPE1	viability after 9 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.4181353671971084	[1945]	[903,697]	3	hSpCas9	negative selection	1125994
28747917	28747940	17	-	26627737	RPE1	viability after 9 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.4625697738994911	[607]	[253,272]	3	hSpCas9	negative selection	1125995
28748650	28748673	17	-	26627737	RPE1	viability after 9 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	0.4404238287680085	[1052]	[528,341]	3	hSpCas9	negative selection	1125996
28749118	28749141	17	+	26627737	RPE1	viability after 9 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-2.1185796255976825	[1172]	[53,123]	-9	hSpCas9	negative selection	1125997
28744111	28744134	17	-	26627737	RPE1	viability after 12 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.2222443265405174	[2087]	[340,628]	-1	hSpCas9	negative selection	1208307
28744116	28744139	17	-	26627737	RPE1	viability after 12 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	-0.04855009262281407	[878]	[188,269]	0	hSpCas9	negative selection	1208308
28747891	28747914	17	+	26627737	RPE1	viability after 12 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.6808677715057874	[1945]	[1012,652]	4	hSpCas9	negative selection	1208309
28747917	28747940	17	-	26627737	RPE1	viability after 12 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.026285770202889858	[607]	[173,145]	0	hSpCas9	negative selection	1208310
28748650	28748673	17	-	26627737	RPE1	viability after 12 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	0.2713823940253292	[1052]	[373,306]	1	hSpCas9	negative selection	1208311
28749118	28749141	17	+	26627737	RPE1	viability after 12 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-2.9373058069706626	[1172]	[11,71]	-9	hSpCas9	negative selection	1208312
28744111	28744134	17	-	26627737	RPE1	viability after 15 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.10976393447165145	[2087]	[497,594]	0	hSpCas9	negative selection	1290622
28744116	28744139	17	-	26627737	RPE1	viability after 15 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.3157829329521197	[878]	[309,308]	2	hSpCas9	negative selection	1290623
28747891	28747914	17	+	26627737	RPE1	viability after 15 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.547474517533006	[1945]	[970,643]	3	hSpCas9	negative selection	1290624
28747917	28747940	17	-	26627737	RPE1	viability after 15 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.08405298607283818	[607]	[164,198]	0	hSpCas9	negative selection	1290625
28748650	28748673	17	-	26627737	RPE1	viability after 15 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	0.898508674699684	[1052]	[764,352]	5	hSpCas9	negative selection	1290626
28749118	28749141	17	+	26627737	RPE1	viability after 15 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-2.001402902952124	[1172]	[89,75]	-8	hSpCas9	negative selection	1290627
28744111	28744134	17	-	26627737	RPE1	viability after 18 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	0.32761877003051176	[2087]	[754,655]	2	hSpCas9	negative selection	1372937
28744116	28744139	17	-	26627737	RPE1	viability after 18 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.007292576427101044	[878]	[133,349]	0	hSpCas9	negative selection	1372938
28747891	28747914	17	+	26627737	RPE1	viability after 18 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.6213044700894876	[1945]	[1050,547]	4	hSpCas9	negative selection	1372939
28747917	28747940	17	-	26627737	RPE1	viability after 18 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.1788689572153796	[607]	[157,130]	-1	hSpCas9	negative selection	1372940
28748650	28748673	17	-	26627737	RPE1	viability after 18 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	0.5317408142467392	[1052]	[594,213]	3	hSpCas9	negative selection	1372941
28749118	28749141	17	+	26627737	RPE1	viability after 18 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-2.37580589539888	[1172]	[16,107]	-8	hSpCas9	negative selection	1372942
28744111	28744134	17	-	26627737	HeLa	viability after 8 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.7937849507411817	[1079]	[485,139,236]	-7	hSpCas9	negative selection	1455252
28744116	28744139	17	-	26627737	HeLa	viability after 8 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.4132232019333095	[235]	[267,61,110]	4	hSpCas9	negative selection	1455253
28747891	28747914	17	+	26627737	HeLa	viability after 8 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	-0.1381520974176318	[1032]	[530,248,467]	-1	hSpCas9	negative selection	1455254
28747917	28747940	17	-	26627737	HeLa	viability after 8 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.6475077174083593	[311]	[237,302,109]	5	hSpCas9	negative selection	1455255
28748650	28748673	17	-	26627737	HeLa	viability after 8 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	0.4441695042863406	[271]	[187,198,105]	4	hSpCas9	negative selection	1455256
28749118	28749141	17	+	26627737	HeLa	viability after 8 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-0.7450740553651046	[444]	[113,112,118]	-6	hSpCas9	negative selection	1455257
28744111	28744134	17	-	26627737	HeLa	viability after 12 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.241795925193667	[1079]	[575,340,224]	-2	hSpCas9	negative selection	1537567
28744116	28744139	17	-	26627737	HeLa	viability after 12 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.3892634454334743	[235]	[113,125,142]	3	hSpCas9	negative selection	1537568
28747891	28747914	17	+	26627737	HeLa	viability after 12 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.42025466245148513	[1032]	[837,349,556]	3	hSpCas9	negative selection	1537569
28747917	28747940	17	-	26627737	HeLa	viability after 12 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.29095979956629703	[311]	[218,91,170]	2	hSpCas9	negative selection	1537570
28748650	28748673	17	-	26627737	HeLa	viability after 12 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	0.057404913192013574	[271]	[99,186,55]	0	hSpCas9	negative selection	1537571
28749118	28749141	17	+	26627737	HeLa	viability after 12 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-1.1984946819645825	[444]	[1,52,185]	-8	hSpCas9	negative selection	1537572
28744111	28744134	17	-	26627737	HeLa	viability after 15 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.49202620682023135	[1079]	[525,145,258]	-4	hSpCas9	negative selection	1619882
28744116	28744139	17	-	26627737	HeLa	viability after 15 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.6267987822627956	[235]	[91,214,137]	5	hSpCas9	negative selection	1619883
28747891	28747914	17	+	26627737	HeLa	viability after 15 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.6184734990896728	[1032]	[715,392,841]	5	hSpCas9	negative selection	1619884
28747917	28747940	17	-	26627737	HeLa	viability after 15 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.0010057580535540178	[311]	[107,116,158]	0	hSpCas9	negative selection	1619885
28748650	28748673	17	-	26627737	HeLa	viability after 15 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	-0.23763275509181558	[271]	[93,126,57]	-2	hSpCas9	negative selection	1619886
28749118	28749141	17	+	26627737	HeLa	viability after 15 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-0.908561729486668	[444]	[55,125,108]	-7	hSpCas9	negative selection	1619887
28744111	28744134	17	-	26627737	HeLa	viability after 18 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.4774907620812978	[1079]	[362,115,258]	-4	hSpCas9	negative selection	1702197
28744116	28744139	17	-	26627737	HeLa	viability after 18 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.6635745939441543	[235]	[65,181,137]	5	hSpCas9	negative selection	1702198
28747891	28747914	17	+	26627737	HeLa	viability after 18 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.632029414194929	[1032]	[486,331,841]	5	hSpCas9	negative selection	1702199
28747917	28747940	17	-	26627737	HeLa	viability after 18 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	2.6851163220154017e-05	[311]	[72,95,158]	0	hSpCas9	negative selection	1702200
28748650	28748673	17	-	26627737	HeLa	viability after 18 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	-0.24553875547379844	[271]	[62,103,57]	-2	hSpCas9	negative selection	1702201
28749118	28749141	17	+	26627737	HeLa	viability after 18 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-0.9478184586836702	[444]	[35,99,108]	-7	hSpCas9	negative selection	1702202
28744111	28744134	17	-	26627737	HCT116	viability after 6 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.0023884894050127947	[888]	[319,39]	0	hSpCas9	negative selection	1784512
28744116	28744139	17	-	26627737	HCT116	viability after 6 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	2.3631698147813593	[195]	[309,74]	9	hSpCas9	negative selection	1784513
28747891	28747914	17	+	26627737	HCT116	viability after 6 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.30094097195765523	[1875]	[673,191]	1	hSpCas9	negative selection	1784514
28747917	28747940	17	-	26627737	HCT116	viability after 6 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.08819481910095223	[614]	[105,100]	0	hSpCas9	negative selection	1784515
28748650	28748673	17	-	26627737	HCT116	viability after 6 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	-1.0269731211885635	[869]	[157,16]	-5	hSpCas9	negative selection	1784516
28749118	28749141	17	+	26627737	HCT116	viability after 6 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	0.5220801229087183	[570]	[28,183]	3	hSpCas9	negative selection	1784517
28744111	28744134	17	-	26627737	HCT116	viability after 8 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	0.31585068536701	[497]	[252,334,433]	3	hSpCas9	negative selection	1866827
28744116	28744139	17	-	26627737	HCT116	viability after 8 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	-0.007426778722805699	[261]	[168,90,170]	0	hSpCas9	negative selection	1866828
28747891	28747914	17	+	26627737	HCT116	viability after 8 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	-0.1740750591892537	[817]	[344,407,443]	-2	hSpCas9	negative selection	1866829
28747917	28747940	17	-	26627737	HCT116	viability after 8 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.3882043357038763	[237]	[98,134,66]	-4	hSpCas9	negative selection	1866830
28748650	28748673	17	-	26627737	HCT116	viability after 8 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	-0.3294103644231777	[211]	[133,81,63]	-4	hSpCas9	negative selection	1866831
28749118	28749141	17	+	26627737	HCT116	viability after 8 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	0.9313666045132326	[128]	[182,127,96]	8	hSpCas9	negative selection	1866832
28744111	28744134	17	-	26627737	HCT116	viability after 9 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	1.0760336273374094	[888]	[519,484]	7	hSpCas9	negative selection	1949142
28744116	28744139	17	-	26627737	HCT116	viability after 9 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	1.3372318827704943	[195]	[253,35]	8	hSpCas9	negative selection	1949143
28747891	28747914	17	+	26627737	HCT116	viability after 9 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.31114582349498443	[1875]	[797,481]	2	hSpCas9	negative selection	1949144
28747917	28747940	17	-	26627737	HCT116	viability after 9 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.17249060554809248	[614]	[274,113]	1	hSpCas9	negative selection	1949145
28748650	28748673	17	-	26627737	HCT116	viability after 9 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	-1.549535107750758	[869]	[156,17]	-8	hSpCas9	negative selection	1949146
28749118	28749141	17	+	26627737	HCT116	viability after 9 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	1.0226767770683032	[570]	[63,503]	7	hSpCas9	negative selection	1949147
28744111	28744134	17	-	26627737	HCT116	viability after 12 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	0.20979347275391025	[497]	[272,193,440]	2	hSpCas9	negative selection	2031457
28744116	28744139	17	-	26627737	HCT116	viability after 12 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.11952298011763134	[261]	[137,76,232]	1	hSpCas9	negative selection	2031458
28747891	28747914	17	+	26627737	HCT116	viability after 12 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	-0.3493642809170394	[817]	[280,368,367]	-4	hSpCas9	negative selection	2031459
28747917	28747940	17	-	26627737	HCT116	viability after 12 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.2918941448376337	[237]	[203,115,133]	3	hSpCas9	negative selection	2031460
28748650	28748673	17	-	26627737	HCT116	viability after 12 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	0.37374440341485904	[211]	[130,92,208]	4	hSpCas9	negative selection	2031461
28749118	28749141	17	+	26627737	HCT116	viability after 12 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	0.22053843005878804	[128]	[76,72,86]	2	hSpCas9	negative selection	2031462
28744111	28744134	17	-	26627737	HCT116	viability after 15 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	0.19408475706287842	[497]	[286,390,298]	2	hSpCas9	negative selection	2113772
28744116	28744139	17	-	26627737	HCT116	viability after 15 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.3231443927507569	[261]	[136,109,309]	3	hSpCas9	negative selection	2113773
28747891	28747914	17	+	26627737	HCT116	viability after 15 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	-0.1538372462641806	[817]	[671,271,353]	-1	hSpCas9	negative selection	2113774
28747917	28747940	17	-	26627737	HCT116	viability after 15 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.9153905381789922	[237]	[125,31,65]	-7	hSpCas9	negative selection	2113775
28748650	28748673	17	-	26627737	HCT116	viability after 15 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	-0.08691498934811626	[211]	[153,105,88]	-1	hSpCas9	negative selection	2113776
28749118	28749141	17	+	26627737	HCT116	viability after 15 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	0.23522179224683937	[128]	[143,76,47]	2	hSpCas9	negative selection	2113777
28744111	28744134	17	-	26627737	HCT116	viability after 18 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	0.2164184205471804	[497]	[235,341,255]	2	hSpCas9	negative selection	2196087
28744116	28744139	17	-	26627737	HCT116	viability after 18 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.09409770754220179	[261]	[45,176,181]	0	hSpCas9	negative selection	2196088
28747891	28747914	17	+	26627737	HCT116	viability after 18 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	-0.06534855272880313	[817]	[287,327,527]	0	hSpCas9	negative selection	2196089
28747917	28747940	17	-	26627737	HCT116	viability after 18 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.49864351183973893	[237]	[134,44,65]	-4	hSpCas9	negative selection	2196090
28748650	28748673	17	-	26627737	HCT116	viability after 18 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	-0.04680815851658804	[211]	[250,33,12]	0	hSpCas9	negative selection	2196091
28749118	28749141	17	+	26627737	HCT116	viability after 18 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	0.6698547196611586	[128]	[120,112,60]	5	hSpCas9	negative selection	2196092
28744111	28744134	17	-	24336569	HL60	viability	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	0.13512392838311588	[675]	[1570]	1	hSpCas9	negative selection	2303271
28744116	28744139	17	-	24336569	HL60	viability	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.13738361366413943	[814]	[1896]	1	hSpCas9	negative selection	2303272
28744135	28744158	17	+	24336569	HL60	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	0.15497609519318434	[218]	[515]	1	hSpCas9	negative selection	2303273
28744146	28744169	17	-	24336569	HL60	viability	GGGCACAGCAGCCGTCGCTTGGG	TRAF4	ENSG00000076604	6.410388995700778	[0]	[179]	9	hSpCas9	negative selection	2303274
28744155	28744178	17	+	24336569	HL60	viability	CGGCTGCTGTGCCCACTGTGCGG	TRAF4	ENSG00000076604	0.5530964465948065	[1419]	[4408]	5	hSpCas9	negative selection	2303275
28744166	28744189	17	-	24336569	HL60	viability	GCATGGGCTTCCCGCACAGTGGG	TRAF4	ENSG00000076604	1.386180824856085	[206]	[1144]	8	hSpCas9	negative selection	2303276
28744181	28744204	17	+	24336569	HL60	viability	GCCCATGCGCGAGCCTGTGCAGG	TRAF4	ENSG00000076604	1.0804807419548592	[281]	[1261]	8	hSpCas9	negative selection	2303277
28744194	28744217	17	+	24336569	HL60	viability	CCTGTGCAGGTTTCCACCTGCGG	TRAF4	ENSG00000076604	-0.0029025561717235804	[678]	[1433]	0	hSpCas9	negative selection	2303278
28744207	28744230	17	-	24336569	HL60	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	-0.6714307514969253	[1082]	[1438]	-6	hSpCas9	negative selection	2303279
28744217	28744240	17	-	24336569	HL60	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.8062367979710723	[443]	[1642]	6	hSpCas9	negative selection	2303280
28744111	28744134	17	-	24336569	KBM7	viability	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	0.1451302817572414	[680]	[2053]	1	hSpCas9	negative selection	2370448
28744116	28744139	17	-	24336569	KBM7	viability	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.48582784383871136	[592]	[2264]	4	hSpCas9	negative selection	2370449
28744135	28744158	17	+	24336569	KBM7	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	1.0411679889129704	[154]	[869]	8	hSpCas9	negative selection	2370450
28744146	28744169	17	-	24336569	KBM7	viability	GGGCACAGCAGCCGTCGCTTGGG	TRAF4	ENSG00000076604	-1.6423075889917673	[197]	[172]	-8	hSpCas9	negative selection	2370451
28744155	28744178	17	+	24336569	KBM7	viability	CGGCTGCTGTGCCCACTGTGCGG	TRAF4	ENSG00000076604	-0.12218532608151822	[1080]	[2708]	-1	hSpCas9	negative selection	2370452
28744166	28744189	17	-	24336569	KBM7	viability	GCATGGGCTTCCCGCACAGTGGG	TRAF4	ENSG00000076604	-0.15945380975225815	[474]	[1159]	-1	hSpCas9	negative selection	2370453
28744181	28744204	17	+	24336569	KBM7	viability	GCCCATGCGCGAGCCTGTGCAGG	TRAF4	ENSG00000076604	0.15596472991399923	[179]	[546]	1	hSpCas9	negative selection	2370454
28744194	28744217	17	+	24336569	KBM7	viability	CCTGTGCAGGTTTCCACCTGCGG	TRAF4	ENSG00000076604	-0.0964773416298659	[420]	[1073]	-1	hSpCas9	negative selection	2370455
28744207	28744230	17	-	24336569	KBM7	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	-0.3184238009088679	[645]	[1412]	-3	hSpCas9	negative selection	2370456
28744217	28744240	17	-	24336569	KBM7	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	1.112918063831545	[336]	[1987]	8	hSpCas9	negative selection	2370457
28748082	28748105	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	0.02008594945377004	[2,2]	[4,0]	0	hSpCas9	positive selection	3028904
28748279	28748302	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CACAGTAGACACTCTCCTGGGGG	TRAF4	ENSG00000076604	0.05356185703763491	[4,4]	[3,3]	1	hSpCas9	positive selection	3028905
28744136	28744159	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	-0.9942572116361409	[1,1]	[0,0]	-9	hSpCas9	positive selection	3028906
28748082	28748105	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	0.7856998982059391	[2,2]	[3,4]	9	hSpCas9	positive selection	3096762
28748279	28748302	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CACAGTAGACACTCTCCTGGGGG	TRAF4	ENSG00000076604	0.2953041707475226	[4,4]	[4,3]	5	hSpCas9	positive selection	3096763
28744136	28744159	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	-0.6086414493815686	[1,1]	[0,0]	-8	hSpCas9	positive selection	3096764
28747930	28747953		-	24336571	A375	resistance to PLX after 7 days	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	0.10625419061282079	[10,8]	[8,12]	3	hSpCas9	positive selection	3152380
28747926	28747949		+	24336571	A375	resistance to PLX after 7 days	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	-0.27103612484179423	[13,18]	[13,12]	-7	hSpCas9	positive selection	3152381
28747930	28747953		-	24336571	A375	resistance to PLX after 14 days	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.05923860492044586	[7,7]	[2,3]	0	hSpCas9	positive selection	3210173
28747926	28747949		+	24336571	A375	resistance to PLX after 14 days	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	-0.5440178428128898	[10,14]	[3,3]	-6	hSpCas9	positive selection	3210174
28747930	28747953		-	24336571	A375	viability after 7 days	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.38036621868984494	[13]	[10,8]	-5	hSpCas9	negative selection	3267966
28747926	28747949		+	24336571	A375	viability after 7 days	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.3628947106689054	[12]	[13,18]	5	hSpCas9	negative selection	3267967
28747930	28747953		-	24336571	A375	viability after 14 days	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.6350814958950871	[13]	[7,7]	-6	hSpCas9	negative selection	3325759
28747926	28747949		+	24336571	A375	viability after 14 days	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.08700234127299301	[12]	[10,14]	1	hSpCas9	negative selection	3325760
28747930	28747953	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.274055249070477	[184,184]	[0,0]	-2	hSpCas9	positive selection	3398802
28748378	28748401	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	-0.9858477720271158	[302,302]	[0,0]	-6	hSpCas9	positive selection	3398803
28748386	28748409	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.41183616050145994	[114,114]	[0,0]	2	hSpCas9	positive selection	3398804
28748082	28748105	17	-	26780180	HT29	viability (Avana library 4 designs)	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	2.34898876880243	[]	[]	8	hSpCas9	negative selection	3467746
28748279	28748302	17	-	26780180	HT29	viability (Avana library 4 designs)	CACAGTAGACACTCTCCTGGGGG	TRAF4	ENSG00000076604	1.33507142905935	[]	[]	5	hSpCas9	negative selection	3467747
28744135	28744158	17	+	26780180	HT29	viability (Avana library 4 designs)	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	2.5025555141516	[]	[]	8	hSpCas9	negative selection	3467748
28748082	28748105	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	0.241993688890997	[]	[]	0	hSpCas9	negative selection	3572068
28744135	28744158	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	-1.56945121872085	[]	[]	-2	hSpCas9	negative selection	3572069
28748279	28748302	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CACAGTAGACACTCTCCTGGGGG	TRAF4	ENSG00000076604	-0.886392084626801	[]	[]	-1	hSpCas9	negative selection	3572070
28748250	28748273	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGACATTTCCAGAGCCATGAGGG	TRAF4	ENSG00000076604	-1.92640721467131	[]	[]	-2	hSpCas9	negative selection	3572071
28744223	28744246	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCTGCGATACCTGCCTGCAGG	TRAF4	ENSG00000076604	-0.0375404057278571	[]	[]	0	hSpCas9	negative selection	3572072
28748082	28748105	17	-	26780180	A375	viability (Avana lentiGuide)	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	4.05628516757401	[]	[]	4	hSpCas9	negative selection	3680727
28744135	28744158	17	+	26780180	A375	viability (Avana lentiGuide)	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	15.0665777016136	[]	[]	8	hSpCas9	negative selection	3680728
28748279	28748302	17	-	26780180	A375	viability (Avana lentiGuide)	CACAGTAGACACTCTCCTGGGGG	TRAF4	ENSG00000076604	-3.41191988403612	[]	[]	-6	hSpCas9	negative selection	3680729
28748250	28748273	17	+	26780180	A375	viability (Avana lentiGuide)	TGACATTTCCAGAGCCATGAGGG	TRAF4	ENSG00000076604	7.01322143181996	[]	[]	5	hSpCas9	negative selection	3680730
28744223	28744246	17	+	26780180	A375	viability (Avana lentiGuide)	TTTCTGCGATACCTGCCTGCAGG	TRAF4	ENSG00000076604	2.74813311539685	[]	[]	3	hSpCas9	negative selection	3680731
28748082	28748105	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-0.12850337809525975	[4]	[4,3]	-2	hSpCas9	positive selection	3789334
28744135	28744158	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	-0.08919594769730593	[3]	[2,3]	-1	hSpCas9	positive selection	3789335
28748279	28748302	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACAGTAGACACTCTCCTGGGGG	TRAF4	ENSG00000076604	-0.08284648416479748	[5]	[5,4]	-1	hSpCas9	positive selection	3789336
28748250	28748273	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGACATTTCCAGAGCCATGAGGG	TRAF4	ENSG00000076604	-0.2010954537943604	[5]	[4,4]	-3	hSpCas9	positive selection	3789337
28744223	28744246	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCTGCGATACCTGCCTGCAGG	TRAF4	ENSG00000076604	0.03809900998772808	[6]	[6,5]	0	hSpCas9	positive selection	3789338
28748082	28748105	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-0.7965141551087418	[5]	[2,2]	-7	hSpCas9	positive selection	3897941
28744135	28744158	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	-1.0414842895076224	[3]	[0,0]	-8	hSpCas9	positive selection	3897942
28748279	28748302	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACAGTAGACACTCTCCTGGGGG	TRAF4	ENSG00000076604	0.010937693103453744	[6]	[4,5]	0	hSpCas9	positive selection	3897943
28748250	28748273	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGACATTTCCAGAGCCATGAGGG	TRAF4	ENSG00000076604	-0.060117209184038206	[5]	[3,5]	-1	hSpCas9	positive selection	3897944
28744223	28744246	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCTGCGATACCTGCCTGCAGG	TRAF4	ENSG00000076604	0.16516900719171723	[7]	[7,7]	4	hSpCas9	positive selection	3897945
28748130	28748153	17	-	26780180	A375	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.738444446500529	[]	[]	2	hSpCas9	negative selection	4007261
28748069	28748092	17	-	26780180	A375	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.121330765852223	[]	[]	0	hSpCas9	negative selection	4007262
28747930	28747953	17	-	26780180	A375	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	0.542077372563112	[]	[]	1	hSpCas9	negative selection	4007263
28748386	28748409	17	-	26780180	A375	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	1.56196807032696	[]	[]	8	hSpCas9	negative selection	4007264
28748378	28748401	17	+	26780180	A375	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	1.39124726576162	[]	[]	7	hSpCas9	negative selection	4007265
28747926	28747949	17	+	26780180	A375	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	1.73971831056948	[]	[]	9	hSpCas9	negative selection	4007266
28748130	28748153	17	-	26780180	HT29	viability (GeCKOv2 library)	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	1.12818692338462	[]	[]	5	hSpCas9	negative selection	4115227
28748069	28748092	17	-	26780180	HT29	viability (GeCKOv2 library)	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.631259883570386	[]	[]	2	hSpCas9	negative selection	4115228
28747930	28747953	17	-	26780180	HT29	viability (GeCKOv2 library)	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	0.660035861924221	[]	[]	2	hSpCas9	negative selection	4115229
28748386	28748409	17	-	26780180	HT29	viability (GeCKOv2 library)	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	1.95857217811962	[]	[]	9	hSpCas9	negative selection	4115230
28748378	28748401	17	+	26780180	HT29	viability (GeCKOv2 library)	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	1.51289891108176	[]	[]	7	hSpCas9	negative selection	4115231
28747926	28747949	17	+	26780180	HT29	viability (GeCKOv2 library)	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	2.71454200362208	[]	[]	9	hSpCas9	negative selection	4115232
28747930	28747953	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.35466484552546995	[3]	[1,1]	-7	hSpCas9	positive selection	4178928
28747926	28747949	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.005454255419032453	[4]	[3,1]	0	hSpCas9	positive selection	4178929
28747930	28747953	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	0.3088966073499163	[3]	[0,2,4,0]	2	hSpCas9	positive selection	4242950
28747926	28747949	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.902299876806456	[4]	[2,0,4,3]	6	hSpCas9	positive selection	4242951
28747926	28747949	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.05952813468435123	[3]	[2,2]	1	hSpCas9	positive selection	4304879
28748130	28748153	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	-0.0009929955880758623	[1]	[1,0]	0	hSpCas9	positive selection	4304880
28748069	28748092	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	-0.08297177744450429	[3]	[3,1]	-2	hSpCas9	positive selection	4304881
28747930	28747953	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	0.27590601709716184	[3]	[3,3]	5	hSpCas9	positive selection	4369128
28748378	28748401	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.1645770425609488	[3]	[2,2]	3	hSpCas9	positive selection	4369129
28748386	28748409	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.3757604093701846	[2]	[2,0]	-7	hSpCas9	positive selection	4369130
28744217	28744239	17	-	27760321	OCIAML3	viability	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.2090166775191028	[438,398]	[335,433]	2	hSpCas9	negative selection	4449676
28747843	28747865	17	+	27760321	OCIAML3	viability	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.11012568797284639	[659,571]	[383,524]	-1	hSpCas9	negative selection	4449677
28747917	28747939	17	-	27760321	OCIAML3	viability	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.06875884911007418	[637,521]	[429,529]	0	hSpCas9	negative selection	4449678
28748312	28748334	17	+	27760321	OCIAML3	viability	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.6742321711500492	[417,403]	[193,211]	-6	hSpCas9	negative selection	4449679
28748379	28748401	17	+	27760321	OCIAML3	viability	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.21697267312640622	[700,588]	[511,677]	2	hSpCas9	negative selection	4449680
28744217	28744239	17	-	27760321	OCIAML2	viability	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.2936046647679225	[438,398]	[243,318]	-4	hSpCas9	negative selection	4533139
28747843	28747865	17	+	27760321	OCIAML2	viability	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.37035139699225655	[659,571]	[610,683]	5	hSpCas9	negative selection	4533140
28747917	28747939	17	-	27760321	OCIAML2	viability	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.39439714109805185	[637,521]	[261,477]	-5	hSpCas9	negative selection	4533141
28748312	28748334	17	+	27760321	OCIAML2	viability	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.04174602893397361	[417,403]	[317,330]	0	hSpCas9	negative selection	4533142
28748379	28748401	17	+	27760321	OCIAML2	viability	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.31124239132021836	[700,588]	[634,657]	4	hSpCas9	negative selection	4533143
28744217	28744239	17	-	27760321	MV411	viability	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.755856563316288	[438,398]	[476,450]	5	hSpCas9	negative selection	4616602
28747843	28747865	17	+	27760321	MV411	viability	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.7937126843557729	[659,571]	[97,437]	-5	hSpCas9	negative selection	4616603
28747917	28747939	17	-	27760321	MV411	viability	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.2101975245201254	[637,521]	[353,291]	-1	hSpCas9	negative selection	4616604
28748312	28748334	17	+	27760321	MV411	viability	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	1.55748690752418	[417,403]	[334,1497]	9	hSpCas9	negative selection	4616605
28748379	28748401	17	+	27760321	MV411	viability	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	-0.46444836361426045	[700,588]	[178,499]	-3	hSpCas9	negative selection	4616606
28744217	28744239	17	-	27760321	HL60	viability	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.6434059568920071	[438,398]	[234,201]	-6	hSpCas9	negative selection	4700065
28747843	28747865	17	+	27760321	HL60	viability	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.2207308399086026	[659,571]	[403,458]	-2	hSpCas9	negative selection	4700066
28747917	28747939	17	-	27760321	HL60	viability	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.08258448398908863	[637,521]	[402,489]	-1	hSpCas9	negative selection	4700067
28748312	28748334	17	+	27760321	HL60	viability	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	0.1364488269258361	[417,403]	[360,378]	1	hSpCas9	negative selection	4700068
28748379	28748401	17	+	27760321	HL60	viability	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	-0.231053535184991	[700,588]	[469,422]	-3	hSpCas9	negative selection	4700069
28744217	28744239	17	-	27760321	HT1080	viability	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.0899133358990117	[398,311]	[176,121]	0	hSpCas9	negative selection	4783528
28747843	28747865	17	+	27760321	HT1080	viability	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.6681846061844738	[571,446]	[58,202]	-3	hSpCas9	negative selection	4783529
28747917	28747939	17	-	27760321	HT1080	viability	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.1344092157893933	[521,407]	[157,252]	0	hSpCas9	negative selection	4783530
28748312	28748334	17	+	27760321	HT1080	viability	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.7540321428457046	[403,314]	[61,109]	-3	hSpCas9	negative selection	4783531
28748379	28748401	17	+	27760321	HT1080	viability	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.4006631148370525	[588,459]	[261,290]	2	hSpCas9	negative selection	4783532
28744217	28744239	17	-	27760321	HT29	viability after 7 days	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.16348590883637093	[398,311]	[448,318,459]	-2	hSpCas9	negative selection	4866991
28747843	28747865	17	+	27760321	HT29	viability after 7 days	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.09959775237364488	[571,446]	[601,831,657]	1	hSpCas9	negative selection	4866992
28747917	28747939	17	-	27760321	HT29	viability after 7 days	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.7158052678834896	[521,407]	[860,977,1084]	9	hSpCas9	negative selection	4866993
28748312	28748334	17	+	27760321	HT29	viability after 7 days	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.3176395350818675	[403,314]	[250,411,429]	-4	hSpCas9	negative selection	4866994
28748379	28748401	17	+	27760321	HT29	viability after 7 days	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.5095602476869445	[588,459]	[1248,869,805]	7	hSpCas9	negative selection	4866995
28744217	28744239	17	-	27760321	HT29	viability after 25 days	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.024098273883132855	[398,311]	[379,412,451]	0	hSpCas9	negative selection	4950454
28747843	28747865	17	+	27760321	HT29	viability after 25 days	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.17877296353219957	[571,446]	[539,511,485]	-2	hSpCas9	negative selection	4950455
28747917	28747939	17	-	27760321	HT29	viability after 25 days	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.29459054618468355	[521,407]	[439,840,690]	3	hSpCas9	negative selection	4950456
28748312	28748334	17	+	27760321	HT29	viability after 25 days	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.6913291990266126	[403,314]	[331,222,196]	-5	hSpCas9	negative selection	4950457
28748379	28748401	17	+	27760321	HT29	viability after 25 days	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.5521698424280614	[588,459]	[794,809,1053]	6	hSpCas9	negative selection	4950458
28744217	28744239	17	-	27760321	HT29	viability after 22 days	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.07197387765545415	[398,311]	[203,593,379]	0	hSpCas9	negative selection	5033917
28747843	28747865	17	+	27760321	HT29	viability after 22 days	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.6721338015813052	[571,446]	[398,362,345]	-5	hSpCas9	negative selection	5033918
28747917	28747939	17	-	27760321	HT29	viability after 22 days	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.1219142119981288	[521,407]	[500,597,658]	1	hSpCas9	negative selection	5033919
28748312	28748334	17	+	27760321	HT29	viability after 22 days	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.5612846048591242	[403,314]	[238,329,276]	-5	hSpCas9	negative selection	5033920
28748379	28748401	17	+	27760321	HT29	viability after 22 days	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.7436523235785226	[588,459]	[1078,864,1100]	8	hSpCas9	negative selection	5033921
28744217	28744239	17	-	27760321	HT29	viability after 19 days	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.16843227484795267	[398,311]	[372,696,297]	1	hSpCas9	negative selection	5117380
28747843	28747865	17	+	27760321	HT29	viability after 19 days	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.16094535258990472	[571,446]	[320,528,685]	-1	hSpCas9	negative selection	5117381
28747917	28747939	17	-	27760321	HT29	viability after 19 days	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.3069014019097989	[521,407]	[647,657,665]	3	hSpCas9	negative selection	5117382
28748312	28748334	17	+	27760321	HT29	viability after 19 days	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.8391055949334465	[403,314]	[205,309,172]	-6	hSpCas9	negative selection	5117383
28748379	28748401	17	+	27760321	HT29	viability after 19 days	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.7166657367711835	[588,459]	[806,1436,704]	7	hSpCas9	negative selection	5117384
28744217	28744239	17	-	27760321	HT29	viability after 16 days	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.22682954007343106	[398,311]	[350,175,497]	-3	hSpCas9	negative selection	5200843
28747843	28747865	17	+	27760321	HT29	viability after 16 days	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.008644381489487762	[571,446]	[770,537,430]	0	hSpCas9	negative selection	5200844
28747917	28747939	17	-	27760321	HT29	viability after 16 days	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.409654210423035	[521,407]	[829,668,587]	4	hSpCas9	negative selection	5200845
28748312	28748334	17	+	27760321	HT29	viability after 16 days	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.680087814801514	[403,314]	[224,271,252]	-6	hSpCas9	negative selection	5200846
28748379	28748401	17	+	27760321	HT29	viability after 16 days	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.6495677065372387	[588,459]	[759,590,1403]	7	hSpCas9	negative selection	5200847
28744217	28744239	17	-	27760321	HT29	viability after 13 days	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.1970934724085699	[398,311]	[253,438,384]	-2	hSpCas9	negative selection	5284306
28747843	28747865	17	+	27760321	HT29	viability after 13 days	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.2958538478959341	[571,446]	[500,607,343]	-4	hSpCas9	negative selection	5284307
28747917	28747939	17	-	27760321	HT29	viability after 13 days	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.23460184024271163	[521,407]	[558,857,495]	3	hSpCas9	negative selection	5284308
28748312	28748334	17	+	27760321	HT29	viability after 13 days	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.36593720786231143	[403,314]	[339,277,350]	-4	hSpCas9	negative selection	5284309
28748379	28748401	17	+	27760321	HT29	viability after 13 days	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.5470085119971333	[588,459]	[576,1018,1060]	7	hSpCas9	negative selection	5284310
28744217	28744239	17	-	27760321	HT29	viability after 10 days	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.03798893718803044	[398,311]	[413,258,614]	0	hSpCas9	negative selection	5367769
28747843	28747865	17	+	27760321	HT29	viability after 10 days	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.4705329413937278	[571,446]	[515,426,433]	-5	hSpCas9	negative selection	5367770
28747917	28747939	17	-	27760321	HT29	viability after 10 days	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.840005270301762	[521,407]	[1043,1038,1034]	9	hSpCas9	negative selection	5367771
28748312	28748334	17	+	27760321	HT29	viability after 10 days	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.15915657968735544	[403,314]	[240,738,238]	-2	hSpCas9	negative selection	5367772
28748379	28748401	17	+	27760321	HT29	viability after 10 days	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.29219805533924925	[588,459]	[804,827,773]	4	hSpCas9	negative selection	5367773
28744217	28744239	17	-	27760321	MOLM13	viability	GCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.37177336513581094	[438,398]	[134,450]	2	hSpCas9	negative selection	5451232
28747843	28747865	17	+	27760321	MOLM13	viability	ATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.3508592059047056	[659,571]	[487,402]	2	hSpCas9	negative selection	5451233
28747917	28747939	17	-	27760321	MOLM13	viability	ACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.9702852405361633	[637,521]	[102,219]	-5	hSpCas9	negative selection	5451234
28748312	28748334	17	+	27760321	MOLM13	viability	TGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	1.0435898405123705	[417,403]	[560,408]	7	hSpCas9	negative selection	5451235
28748379	28748401	17	+	27760321	MOLM13	viability	CCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.963184876144998	[700,588]	[884,554]	6	hSpCas9	negative selection	5451236
28747926	28747949	17	+	27260156	BXPC3	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.1858265689195834	[515]	[567,652,552,686]	4	hSpCas9	negative selection	5577339
28748130	28748153	17	-	27260156	BXPC3	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.15606503465534027	[89]	[104,85,116,112]	3	hSpCas9	negative selection	5577340
28748069	28748092	17	-	27260156	BXPC3	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.17973743900925404	[542]	[600,599,686,693]	4	hSpCas9	negative selection	5577341
28747930	28747953	17	-	27260156	BXPC3	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.06426821171040953	[902]	[866,825,906,1029]	-1	hSpCas9	negative selection	5641588
28748378	28748401	17	+	27260156	BXPC3	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.3165548167255099	[630]	[779,837,808,861]	7	hSpCas9	negative selection	5641589
28748386	28748409	17	-	27260156	BXPC3	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.11300675570026508	[282]	[350,354,284,274]	2	hSpCas9	negative selection	5641590
28747926	28747949	17	+	27260156	A673	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.06207876664508055	[515]	[681,551,680,678]	1	hSpCas9	negative selection	5698590
28748130	28748153	17	-	27260156	A673	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.40382031725415013	[89]	[182,152,131,105]	8	hSpCas9	negative selection	5698591
28748069	28748092	17	-	27260156	A673	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.09266435042228904	[542]	[728,625,587,851]	2	hSpCas9	negative selection	5698592
28747930	28747953	17	-	27260156	A673	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.0734261109765163	[902]	[1162,915,1087,966]	-2	hSpCas9	negative selection	5762839
28748378	28748401	17	+	27260156	A673	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.29672268727815276	[630]	[924,887,1018,885]	7	hSpCas9	negative selection	5762840
28748386	28748409	17	-	27260156	A673	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.1096783787099227	[282]	[422,343,356,347]	2	hSpCas9	negative selection	5762841
28747926	28747949	17	+	27260156	A375	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.18337672264397978	[515]	[799,718,615,613]	2	hSpCas9	negative selection	5819841
28748130	28748153	17	-	27260156	A375	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.42504062225203665	[89]	[126,64,161,192]	6	hSpCas9	negative selection	5819842
28748069	28748092	17	-	27260156	A375	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.2981919278256933	[542]	[745,857,826,704]	4	hSpCas9	negative selection	5819843
28747930	28747953	17	-	27260156	A375	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.3433554731247159	[902]	[695,1009,818,821]	-5	hSpCas9	negative selection	5884090
28748378	28748401	17	+	27260156	A375	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.12226394427904952	[630]	[678,998,815,744]	1	hSpCas9	negative selection	5884091
28748386	28748409	17	-	27260156	A375	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.13034916586543854	[282]	[334,353,499,266]	1	hSpCas9	negative selection	5884092
28747926	28747949	17	+	27260156	COLO741	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.10919131209869495	[515]	[791,739,613]	2	hSpCas9	negative selection	5941092
28748130	28748153	17	-	27260156	COLO741	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.7982930979958767	[89]	[142,240,209]	9	hSpCas9	negative selection	5941093
28748069	28748092	17	-	27260156	COLO741	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.0837736205835743	[542]	[691,778,729]	1	hSpCas9	negative selection	5941094
28747930	28747953	17	-	27260156	COLO741	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.007242974015919779	[902]	[1155,1192,1096]	0	hSpCas9	negative selection	6005341
28748378	28748401	17	+	27260156	COLO741	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.2383115470764382	[630]	[1271,869,750]	5	hSpCas9	negative selection	6005342
28748386	28748409	17	-	27260156	COLO741	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.17913061718865841	[282]	[374,475,375]	4	hSpCas9	negative selection	6005343
28747926	28747949	17	+	27260156	CAL120	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.442535360307738	[515]	[858,803,950]	6	hSpCas9	negative selection	6062343
28748130	28748153	17	-	27260156	CAL120	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.29528172131493724	[89]	[194,149,76]	4	hSpCas9	negative selection	6062344
28748069	28748092	17	-	27260156	CAL120	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.4000127579334996	[542]	[972,727,983]	6	hSpCas9	negative selection	6062345
28747930	28747953	17	-	27260156	CAL120	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	0.062399212802731974	[902]	[1640,779,1168]	0	hSpCas9	negative selection	6126592
28748378	28748401	17	+	27260156	CAL120	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.826825434724201	[630]	[1149,1919,1076]	9	hSpCas9	negative selection	6126593
28748386	28748409	17	-	27260156	CAL120	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.6075802292175816	[282]	[645,498,481]	8	hSpCas9	negative selection	6126594
28747926	28747949	17	+	27260156	CADOES1	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.1751501641082853	[515]	[513,587,589,472]	3	hSpCas9	negative selection	6183594
28748130	28748153	17	-	27260156	CADOES1	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.3869809233213324	[89]	[101,109,137,86]	6	hSpCas9	negative selection	6183595
28748069	28748092	17	-	27260156	CADOES1	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.12604998517901966	[542]	[562,476,595,568]	2	hSpCas9	negative selection	6183596
28747930	28747953	17	-	27260156	CADOES1	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.2708010503487154	[902]	[663,739,521,864]	-5	hSpCas9	negative selection	6247843
28748378	28748401	17	+	27260156	CADOES1	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.32463412509125456	[630]	[722,732,719,764]	5	hSpCas9	negative selection	6247844
28748386	28748409	17	-	27260156	CADOES1	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.19950933383594804	[282]	[354,241,301,309]	3	hSpCas9	negative selection	6247845
28747926	28747949	17	+	27260156	EWS502	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.23561481636355755	[515]	[552,770,621,629]	4	hSpCas9	negative selection	6304845
28748130	28748153	17	-	27260156	EWS502	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.5388529425191166	[89]	[100,129,173,154]	8	hSpCas9	negative selection	6304846
28748069	28748092	17	-	27260156	EWS502	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.29981857026558884	[542]	[555,688,705,911]	5	hSpCas9	negative selection	6304847
28747930	28747953	17	-	27260156	EWS502	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.08375097187549019	[902]	[693,843,1185,914]	-1	hSpCas9	negative selection	6369094
28748378	28748401	17	+	27260156	EWS502	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.27625924767790166	[630]	[756,684,827,988]	5	hSpCas9	negative selection	6369095
28748386	28748409	17	-	27260156	EWS502	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.5175756821594976	[282]	[114,218,323,189]	-7	hSpCas9	negative selection	6369096
28747926	28747949	17	+	27260156	EW8	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.13261145537863753	[515]	[433,387,542,449]	2	hSpCas9	negative selection	6426096
28748130	28748153	17	-	27260156	EW8	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.6358972710984665	[89]	[149,63,171,60]	9	hSpCas9	negative selection	6426097
28748069	28748092	17	-	27260156	EW8	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.14924916535627475	[542]	[487,619,455,392]	2	hSpCas9	negative selection	6426098
28747930	28747953	17	-	27260156	EW8	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	0.08415659005520015	[902]	[680,769,901,715]	1	hSpCas9	negative selection	6490345
28748378	28748401	17	+	27260156	EW8	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	-0.1335124566852115	[630]	[606,368,414,495]	-3	hSpCas9	negative selection	6490346
28748386	28748409	17	-	27260156	EW8	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.06949508277159833	[282]	[330,248,235,156]	1	hSpCas9	negative selection	6490347
28747926	28747949	17	+	27260156	CORL105	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.1762557096561215	[515]	[573,731,756,673]	3	hSpCas9	negative selection	6547347
28748130	28748153	17	-	27260156	CORL105	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.3519866987869653	[89]	[89,60,188,205]	6	hSpCas9	negative selection	6547348
28748069	28748092	17	-	27260156	CORL105	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	-0.12698310322106243	[542]	[604,476,645,612]	-2	hSpCas9	negative selection	6547349
28747930	28747953	17	-	27260156	CORL105	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.36163407293972827	[902]	[889,880,882,647]	-6	hSpCas9	negative selection	6611596
28748378	28748401	17	+	27260156	CORL105	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.07742917940167893	[630]	[750,685,836,852]	1	hSpCas9	negative selection	6611597
28748386	28748409	17	-	27260156	CORL105	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.05852420327589847	[282]	[248,482,362,281]	1	hSpCas9	negative selection	6611598
28747926	28747949	17	+	27260156	HS294T	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.08746470092358166	[515]	[205,210,242,182]	1	hSpCas9	negative selection	6668598
28748130	28748153	17	-	27260156	HS294T	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	1.0061673940070095	[89]	[35,40,94,119]	9	hSpCas9	negative selection	6668599
28748069	28748092	17	-	27260156	HS294T	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.1657272301029103	[542]	[180,258,288,212]	2	hSpCas9	negative selection	6668600
28747930	28747953	17	-	27260156	HS294T	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.49036715904751615	[902]	[160,231,282,341]	-6	hSpCas9	negative selection	6732847
28748378	28748401	17	+	27260156	HS294T	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	-0.0789009908751141	[630]	[225,182,201,330]	-1	hSpCas9	negative selection	6732848
28748386	28748409	17	-	27260156	HS294T	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.3508491249988549	[282]	[84,71,77,112]	-5	hSpCas9	negative selection	6732849
28747926	28747949	17	+	27260156	HCC44	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	-0.0010740048161304583	[515]	[455,484,803,621]	0	hSpCas9	negative selection	6789849
28748130	28748153	17	-	27260156	HCC44	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	-0.13457821118474378	[89]	[124,74,62,106]	-2	hSpCas9	negative selection	6789850
28748069	28748092	17	-	27260156	HCC44	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.35816430889592826	[542]	[1166,529,618,865]	6	hSpCas9	negative selection	6789851
28747930	28747953	17	-	27260156	HCC44	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.2036208440509384	[902]	[933,819,1046,783]	-3	hSpCas9	negative selection	6854098
28748378	28748401	17	+	27260156	HCC44	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.1663846541962195	[630]	[883,798,848,684]	2	hSpCas9	negative selection	6854099
28748386	28748409	17	-	27260156	HCC44	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.25347579741170034	[282]	[217,288,385,193]	-4	hSpCas9	negative selection	6854100
28747926	28747949	17	+	27260156	G402	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.044682360780033514	[515]	[565,963,857,233]	0	hSpCas9	negative selection	6911100
28748130	28748153	17	-	27260156	G402	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	1.4433975205004677	[89]	[115,703,290,89]	9	hSpCas9	negative selection	6911101
28748069	28748092	17	-	27260156	G402	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	-0.07468147852959989	[542]	[482,872,750,410]	-1	hSpCas9	negative selection	6911102
28747930	28747953	17	-	27260156	G402	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.035043648368436875	[902]	[1123,1185,779,1213]	0	hSpCas9	negative selection	6975349
28748378	28748401	17	+	27260156	G402	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.38646152835910075	[630]	[1029,811,952,1208]	5	hSpCas9	negative selection	6975350
28748386	28748409	17	-	27260156	G402	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.1123694325329263	[282]	[428,191,366,297]	-1	hSpCas9	negative selection	6975351
28747926	28747949	17	+	27260156	L33	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.243553473471861	[515]	[547,266,438,547]	5	hSpCas9	negative selection	7032351
28748130	28748153	17	-	27260156	L33	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.5565997034515617	[89]	[83,53,109,139]	9	hSpCas9	negative selection	7032352
28748069	28748092	17	-	27260156	L33	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	-0.1802071929773647	[542]	[505,175,294,510]	-4	hSpCas9	negative selection	7032353
28747930	28747953	17	-	27260156	L33	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.13058335486008854	[902]	[783,304,534,919]	-3	hSpCas9	negative selection	7096600
28748378	28748401	17	+	27260156	L33	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.3376369554481805	[630]	[552,378,650,683]	7	hSpCas9	negative selection	7096601
28748386	28748409	17	-	27260156	L33	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.1175818061899323	[282]	[170,86,156,410]	-3	hSpCas9	negative selection	7096602
28747926	28747949	17	+	27260156	K562	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.4119233069555185	[515]	[574,533,901,436]	5	hSpCas9	negative selection	7153602
28748130	28748153	17	-	27260156	K562	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.6428840460865441	[89]	[232,31,71,160]	7	hSpCas9	negative selection	7153603
28748069	28748092	17	-	27260156	K562	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.23923104656792288	[542]	[852,449,344,633]	3	hSpCas9	negative selection	7153604
28747930	28747953	17	-	27260156	K562	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	0.2298129216305489	[902]	[510,1014,1533,692]	3	hSpCas9	negative selection	7217851
28748378	28748401	17	+	27260156	K562	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.16239145495837926	[630]	[732,636,428,704]	2	hSpCas9	negative selection	7217852
28748386	28748409	17	-	27260156	K562	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.14066758631454912	[282]	[399,210,376,140]	1	hSpCas9	negative selection	7217853
28747926	28747949	17	+	27260156	HT29	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.29621954524185967	[515]	[791,785,879,636]	6	hSpCas9	negative selection	7274853
28748130	28748153	17	-	27260156	HT29	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.4495571128811573	[89]	[105,160,193,134]	8	hSpCas9	negative selection	7274854
28748069	28748092	17	-	27260156	HT29	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.2816460908177632	[542]	[1008,944,665,632]	5	hSpCas9	negative selection	7274855
28747930	28747953	17	-	27260156	HT29	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.2005166220051089	[902]	[989,951,977,902]	-4	hSpCas9	negative selection	7339102
28748378	28748401	17	+	27260156	HT29	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.03163067516996326	[630]	[1012,706,713,715]	0	hSpCas9	negative selection	7339103
28748386	28748409	17	-	27260156	HT29	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.28634045787445417	[282]	[430,553,358,351]	5	hSpCas9	negative selection	7339104
28747926	28747949	17	+	27260156	MHHES1	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.11436636796206223	[515]	[614,888,660,412]	2	hSpCas9	negative selection	7396104
28748130	28748153	17	-	27260156	MHHES1	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.26195828690144474	[89]	[89,155,155,88]	5	hSpCas9	negative selection	7396105
28748069	28748092	17	-	27260156	MHHES1	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.4657620168507067	[542]	[1125,968,676,672]	7	hSpCas9	negative selection	7396106
28747930	28747953	17	-	27260156	MHHES1	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.11856475923677523	[902]	[1249,894,1033,648]	-2	hSpCas9	negative selection	7460353
28748378	28748401	17	+	27260156	MHHES1	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.25758826225603526	[630]	[876,1017,907,644]	5	hSpCas9	negative selection	7460354
28748386	28748409	17	-	27260156	MHHES1	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.15938116079365683	[282]	[372,432,107,252]	-3	hSpCas9	negative selection	7460355
28747926	28747949	17	+	27260156	MEWO	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	-0.045537101371134744	[515]	[639,368,427]	-1	hSpCas9	negative selection	7517355
28748130	28748153	17	-	27260156	MEWO	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.23114698937862732	[89]	[146,58,99]	5	hSpCas9	negative selection	7517356
28748069	28748092	17	-	27260156	MEWO	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	-0.13187562884806298	[542]	[530,431,440]	-3	hSpCas9	negative selection	7517357
28747930	28747953	17	-	27260156	MEWO	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	0.060295963358476756	[902]	[912,805,929]	1	hSpCas9	negative selection	7581604
28748378	28748401	17	+	27260156	MEWO	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.21349001871155826	[630]	[872,652,563]	4	hSpCas9	negative selection	7581605
28748386	28748409	17	-	27260156	MEWO	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.09134907841899387	[282]	[393,247,225]	2	hSpCas9	negative selection	7581606
28747926	28747949	17	+	27260156	LNCAPCLONEFGC	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.08678452844226217	[515]	[643,267,492,591]	1	hSpCas9	negative selection	7638606
28748130	28748153	17	-	27260156	LNCAPCLONEFGC	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.1541941033350276	[89]	[62,58,127,120]	2	hSpCas9	negative selection	7638607
28748069	28748092	17	-	27260156	LNCAPCLONEFGC	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.10028740195462099	[542]	[530,369,485,725]	1	hSpCas9	negative selection	7638608
28747930	28747953	17	-	27260156	LNCAPCLONEFGC	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.4675258969698566	[902]	[583,448,729,632]	-6	hSpCas9	negative selection	7702855
28748378	28748401	17	+	27260156	LNCAPCLONEFGC	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	-0.11780616277869976	[630]	[529,469,597,522]	-2	hSpCas9	negative selection	7702856
28748386	28748409	17	-	27260156	LNCAPCLONEFGC	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.035282068811633316	[282]	[271,253,237,233]	0	hSpCas9	negative selection	7702857
28747926	28747949	17	+	27260156	PANC0327	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.2634909058714946	[515]	[543,427,607,635]	4	hSpCas9	negative selection	7759857
28748130	28748153	17	-	27260156	PANC0327	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	-0.06725614619332854	[89]	[53,17,142,95]	-1	hSpCas9	negative selection	7759858
28748069	28748092	17	-	27260156	PANC0327	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.48901783587966435	[542]	[738,658,623,692]	7	hSpCas9	negative selection	7759859
28747930	28747953	17	-	27260156	PANC0327	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	0.25883516100564075	[902]	[1198,888,1108,670]	4	hSpCas9	negative selection	7824106
28748378	28748401	17	+	27260156	PANC0327	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.14926698482483924	[630]	[638,573,684,595]	2	hSpCas9	negative selection	7824107
28748386	28748409	17	-	27260156	PANC0327	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.07483968485597059	[282]	[328,125,204,421]	1	hSpCas9	negative selection	7824108
28747926	28747949	17	+	27260156	NCIH2009	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.08407063771951231	[515]	[874,663,775]	1	hSpCas9	negative selection	7881108
28748130	28748153	17	-	27260156	NCIH2009	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.18360743391412715	[89]	[213,101,126]	2	hSpCas9	negative selection	7881109
28748069	28748092	17	-	27260156	NCIH2009	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.11207753972573792	[542]	[846,752,864]	1	hSpCas9	negative selection	7881110
28747930	28747953	17	-	27260156	NCIH2009	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.4401783943981399	[902]	[1271,801,783]	-5	hSpCas9	negative selection	7945357
28748378	28748401	17	+	27260156	NCIH2009	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.37198497733437996	[630]	[1305,1164,981]	5	hSpCas9	negative selection	7945358
28748386	28748409	17	-	27260156	NCIH2009	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.08075350554866567	[282]	[451,332,476]	1	hSpCas9	negative selection	7945359
28747926	28747949	17	+	27260156	NCIH1373	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.06604825989582741	[515]	[855,460,569,153]	0	hSpCas9	negative selection	8002359
28748130	28748153	17	-	27260156	NCIH1373	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	-0.7336374379267849	[89]	[173,21,25,10]	-6	hSpCas9	negative selection	8002360
28748069	28748092	17	-	27260156	NCIH1373	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.17997958482906617	[542]	[734,600,751,178]	1	hSpCas9	negative selection	8002361
28747930	28747953	17	-	27260156	NCIH1373	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.5156087205188102	[902]	[979,430,762,190]	-5	hSpCas9	negative selection	8066608
28748378	28748401	17	+	27260156	NCIH1373	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	-0.0665374305988558	[630]	[845,354,904,169]	0	hSpCas9	negative selection	8066609
28748386	28748409	17	-	27260156	NCIH1373	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.41553631948968656	[282]	[284,731,248,96]	4	hSpCas9	negative selection	8066610
28747926	28747949	17	+	27260156	PATU8902	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.023136407535647247	[515]	[881,649,509,954]	0	hSpCas9	negative selection	8123610
28748130	28748153	17	-	27260156	PATU8902	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	-0.6201558781879379	[89]	[200,35,12,92]	-5	hSpCas9	negative selection	8123611
28748069	28748092	17	-	27260156	PATU8902	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.3341341819733748	[542]	[1292,717,631,1279]	3	hSpCas9	negative selection	8123612
28747930	28747953	17	-	27260156	PATU8902	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.638618754604743	[902]	[469,782,851,1153]	-6	hSpCas9	negative selection	8187859
28748378	28748401	17	+	27260156	PATU8902	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	-0.3023358647568427	[630]	[1033,496,633,692]	-3	hSpCas9	negative selection	8187860
28748386	28748409	17	-	27260156	PATU8902	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.07672225721383097	[282]	[384,358,379,364]	0	hSpCas9	negative selection	8187861
28747926	28747949	17	+	27260156	PANC1	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.055097038181528	[515]	[501,571,327,453]	0	hSpCas9	negative selection	8244861
28748130	28748153	17	-	27260156	PANC1	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.9438020117044528	[89]	[146,294,113,77]	9	hSpCas9	negative selection	8244862
28748069	28748092	17	-	27260156	PANC1	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.18201972659443805	[542]	[383,682,701,396]	3	hSpCas9	negative selection	8244863
28747930	28747953	17	-	27260156	PANC1	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.46733880947428585	[902]	[409,974,544,416]	-6	hSpCas9	negative selection	8309110
28748378	28748401	17	+	27260156	PANC1	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.04278953191939411	[630]	[586,637,457,555]	0	hSpCas9	negative selection	8309111
28748386	28748409	17	-	27260156	PANC1	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.3200768572032202	[282]	[234,317,253,390]	5	hSpCas9	negative selection	8309112
28747926	28747949	17	+	27260156	PANC0813	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.18165680353906635	[515]	[617,774,780,574]	3	hSpCas9	negative selection	8366112
28748130	28748153	17	-	27260156	PANC0813	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.3496628001122146	[89]	[109,133,149,141]	5	hSpCas9	negative selection	8366113
28748069	28748092	17	-	27260156	PANC0813	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.15829502922794658	[542]	[684,847,822,499]	2	hSpCas9	negative selection	8366114
28747930	28747953	17	-	27260156	PANC0813	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.7388521734272017	[902]	[773,673,670,445]	-8	hSpCas9	negative selection	8430361
28748378	28748401	17	+	27260156	PANC0813	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	-0.17701805047420935	[630]	[703,671,584,663]	-3	hSpCas9	negative selection	8430362
28748386	28748409	17	-	27260156	PANC0813	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.06209761691144999	[282]	[430,187,315,346]	-1	hSpCas9	negative selection	8430363
28747926	28747949	17	+	27260156	RDES	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.28483407482684076	[515]	[555,683,802,896]	4	hSpCas9	negative selection	8487363
28748130	28748153	17	-	27260156	RDES	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.37828945511727463	[89]	[72,142,181,153]	6	hSpCas9	negative selection	8487364
28748069	28748092	17	-	27260156	RDES	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.2999700554555966	[542]	[664,633,887,928]	5	hSpCas9	negative selection	8487365
28747930	28747953	17	-	27260156	RDES	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.4624181752545808	[902]	[645,616,774,1033]	-7	hSpCas9	negative selection	8551612
28748378	28748401	17	+	27260156	RDES	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.03562106316848174	[630]	[509,607,1035,899]	0	hSpCas9	negative selection	8551613
28748386	28748409	17	-	27260156	RDES	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.08404766413970588	[282]	[304,237,367,317]	-1	hSpCas9	negative selection	8551614
28747926	28747949	17	+	27260156	PC3	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	-0.026074063231862704	[515]	[328,312,1227,469]	0	hSpCas9	negative selection	8608614
28748130	28748153	17	-	27260156	PC3	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	-0.05937548532107462	[89]	[40,123,149,63]	-1	hSpCas9	negative selection	8608615
28748069	28748092	17	-	27260156	PC3	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.11661971119088549	[542]	[393,501,950,674]	2	hSpCas9	negative selection	8608616
28747930	28747953	17	-	27260156	PC3	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	0.014317583182269944	[902]	[653,674,1862,839]	0	hSpCas9	negative selection	8672863
28748378	28748401	17	+	27260156	PC3	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.19803058697354758	[630]	[440,545,1195,963]	4	hSpCas9	negative selection	8672864
28748386	28748409	17	-	27260156	PC3	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.14587303539905805	[282]	[126,175,678,243]	-3	hSpCas9	negative selection	8672865
28747926	28747949	17	+	27260156	PATU8988T	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.01410093034679516	[515]	[453,495,455,616]	0	hSpCas9	negative selection	8729865
28748130	28748153	17	-	27260156	PATU8988T	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.4777782730800253	[89]	[131,155,71,128]	7	hSpCas9	negative selection	8729866
28748069	28748092	17	-	27260156	PATU8988T	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	-0.30118450455408136	[542]	[339,490,334,554]	-5	hSpCas9	negative selection	8729867
28747930	28747953	17	-	27260156	PATU8988T	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.4055953777950898	[902]	[541,623,789,674]	-6	hSpCas9	negative selection	8794114
28748378	28748401	17	+	27260156	PATU8988T	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	-0.2473838543344315	[630]	[318,642,526,582]	-4	hSpCas9	negative selection	8794115
28748386	28748409	17	-	27260156	PATU8988T	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.6356036393483738	[282]	[148,201,124,235]	-7	hSpCas9	negative selection	8794116
28747926	28747949	17	+	27260156	T47D	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.028282745349225646	[515]	[677,550,626,600]	0	hSpCas9	negative selection	8851116
28748130	28748153	17	-	27260156	T47D	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.7348045254603512	[89]	[183,132,188,195]	9	hSpCas9	negative selection	8851117
28748069	28748092	17	-	27260156	T47D	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.20678501183059556	[542]	[705,760,748,699]	4	hSpCas9	negative selection	8851118
28747930	28747953	17	-	27260156	T47D	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.11452171799359612	[902]	[1009,969,881,1027]	-3	hSpCas9	negative selection	8915365
28748378	28748401	17	+	27260156	T47D	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.22012600864842313	[630]	[910,815,778,925]	5	hSpCas9	negative selection	8915366
28748386	28748409	17	-	27260156	T47D	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.250377433444352	[282]	[376,320,386,492]	5	hSpCas9	negative selection	8915367
28747926	28747949	17	+	27260156	SU8686	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.20120570831188198	[515]	[447,595,630,708]	3	hSpCas9	negative selection	8972367
28748130	28748153	17	-	27260156	SU8686	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.4525461510376969	[89]	[106,86,156,147]	7	hSpCas9	negative selection	8972368
28748069	28748092	17	-	27260156	SU8686	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.10128921332475593	[542]	[495,546,598,696]	1	hSpCas9	negative selection	8972369
28747930	28747953	17	-	27260156	SU8686	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.3031037720523151	[902]	[585,699,775,880]	-5	hSpCas9	negative selection	9036616
28748378	28748401	17	+	27260156	SU8686	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.21525474578431247	[630]	[664,648,780,841]	3	hSpCas9	negative selection	9036617
28748386	28748409	17	-	27260156	SU8686	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.4006285318505737	[282]	[192,205,193,266]	-6	hSpCas9	negative selection	9036618
28747926	28747949	17	+	27260156	SKES1	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.30643342190583023	[515]	[711,715,597,544]	6	hSpCas9	negative selection	9093618
28748130	28748153	17	-	27260156	SKES1	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.4070465448247629	[89]	[137,162,119,67]	8	hSpCas9	negative selection	9093619
28748069	28748092	17	-	27260156	SKES1	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.22823272869907724	[542]	[850,832,582,352]	5	hSpCas9	negative selection	9093620
28747930	28747953	17	-	27260156	SKES1	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.2449205777662068	[902]	[891,855,629,693]	-5	hSpCas9	negative selection	9157867
28748378	28748401	17	+	27260156	SKES1	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.23459760460722145	[630]	[1032,746,620,611]	5	hSpCas9	negative selection	9157868
28748386	28748409	17	-	27260156	SKES1	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.3490465027747546	[282]	[234,156,204,274]	-6	hSpCas9	negative selection	9157869
28747926	28747949	17	+	27260156	TOV112D	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.10210704442915172	[515]	[750,624,439,438]	2	hSpCas9	negative selection	9214869
28748130	28748153	17	-	27260156	TOV112D	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	-0.23617982882140476	[89]	[36,22,62,163]	-4	hSpCas9	negative selection	9214870
28748069	28748092	17	-	27260156	TOV112D	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.11629892345627896	[542]	[673,537,605,534]	2	hSpCas9	negative selection	9214871
28747930	28747953	17	-	27260156	TOV112D	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.06155088737399239	[902]	[799,1005,974,716]	-1	hSpCas9	negative selection	9279118
28748378	28748401	17	+	27260156	TOV112D	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	-0.042203848543175826	[630]	[630,587,647,582]	-1	hSpCas9	negative selection	9279119
28748386	28748409	17	-	27260156	TOV112D	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.20628041057630397	[282]	[284,359,228,434]	4	hSpCas9	negative selection	9279120
28747926	28747949	17	+	27260156	TC71	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	-0.0802914611960461	[515]	[564,549,494,479]	-2	hSpCas9	negative selection	9336120
28748130	28748153	17	-	27260156	TC71	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	0.49103691342374045	[89]	[98,119,141,184]	9	hSpCas9	negative selection	9336121
28748069	28748092	17	-	27260156	TC71	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.06507693689623761	[542]	[611,636,603,580]	1	hSpCas9	negative selection	9336122
28747930	28747953	17	-	27260156	TC71	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.035115479735187805	[902]	[894,935,1000,945]	-1	hSpCas9	negative selection	9400369
28748378	28748401	17	+	27260156	TC71	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.06704005827519594	[630]	[710,661,698,765]	1	hSpCas9	negative selection	9400370
28748386	28748409	17	-	27260156	TC71	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	-0.11278595923268453	[282]	[255,341,243,281]	-3	hSpCas9	negative selection	9400371
28747926	28747949	17	+	27260156	TC32	viability	TGGGCCACTACGTCATCTACAGG	TRAF4	ENSG00000076604	0.3826541257156776	[515]	[640,521,874,527]	6	hSpCas9	negative selection	9457371
28748130	28748153	17	-	27260156	TC32	viability	AGCCACAAAACTCGCACTTGAGG	TRAF4	ENSG00000076604	-0.15875498008411348	[89]	[132,15,92,74]	-3	hSpCas9	negative selection	9457372
28748069	28748092	17	-	27260156	TC32	viability	ATCACGGCGGCTCAGCTTCATGG	TRAF4	ENSG00000076604	0.21670157177766847	[542]	[512,506,773,616]	4	hSpCas9	negative selection	9457373
28747930	28747953	17	-	27260156	TC32	viability	CTCACCTGTAGATGACGTAGTGG	TRAF4	ENSG00000076604	-0.19364238204969142	[902]	[659,665,802,847]	-3	hSpCas9	negative selection	9521620
28748378	28748401	17	+	27260156	TC32	viability	GCCCTGCACCTACTGCACTAAGG	TRAF4	ENSG00000076604	0.23660024162576543	[630]	[658,552,864,767]	4	hSpCas9	negative selection	9521621
28748386	28748409	17	-	27260156	TC32	viability	GACGAACTCCTTAGTGCAGTAGG	TRAF4	ENSG00000076604	0.10890115840758663	[282]	[296,240,278,328]	2	hSpCas9	negative selection	9521622
28744111	28744134	17	-	27869803	HPAFII	viability after 27 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.227054509497987	[592]	[291,244,NaN]	-2	hSpCas9	negative selection	9559750
28744116	28744139	17	-	27869803	HPAFII	viability after 27 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	1.7737810582343778	[137]	[198,288,NaN]	9	hSpCas9	negative selection	9559751
28747891	28747914	17	+	27869803	HPAFII	viability after 27 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.7936046358597386	[530]	[412,542,NaN]	6	hSpCas9	negative selection	9559752
28747917	28747940	17	-	27869803	HPAFII	viability after 27 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.6580485369419845	[262]	[347,109,NaN]	5	hSpCas9	negative selection	9559753
28748650	28748673	17	-	27869803	HPAFII	viability after 27 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	-0.09547856140489797	[171]	[118,55,NaN]	0	hSpCas9	negative selection	9559754
28749118	28749141	17	+	27869803	HPAFII	viability after 27 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-2.469566886007251	[271]	[33,18,NaN]	-8	hSpCas9	negative selection	9559755
28744111	28744134	17	-	27869803	HPAFII	viability after 15 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.557633476908395	[592]	[625,312,NaN]	-6	hSpCas9	negative selection	9642199
28744116	28744139	17	-	27869803	HPAFII	viability after 15 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	1.3400821089962132	[137]	[483,307,NaN]	9	hSpCas9	negative selection	9642200
28747891	28747914	17	+	27869803	HPAFII	viability after 15 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.6924979951687513	[530]	[748,1029,NaN]	7	hSpCas9	negative selection	9642201
28747917	28747940	17	-	27869803	HPAFII	viability after 15 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.148319945159	[262]	[312,218,NaN]	-2	hSpCas9	negative selection	9642202
28748650	28748673	17	-	27869803	HPAFII	viability after 15 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	0.09556014364387355	[171]	[326,116,NaN]	1	hSpCas9	negative selection	9642203
28749118	28749141	17	+	27869803	HPAFII	viability after 15 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-1.0130758024751896	[271]	[261,71,NaN]	-7	hSpCas9	negative selection	9642204
28744111	28744134	17	-	27869803	ASPC1	viability after 36 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	0.3296115737404678	[1186]	[576,634,384]	3	hSpCas9	negative selection	9724648
28744116	28744139	17	-	27869803	ASPC1	viability after 36 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	0.8941782202273738	[347]	[175,40,404]	8	hSpCas9	negative selection	9724649
28747891	28747914	17	+	27869803	ASPC1	viability after 36 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.2781237031795072	[1284]	[415,1014,253]	3	hSpCas9	negative selection	9724650
28747917	28747940	17	-	27869803	ASPC1	viability after 36 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.5138782581424395	[804]	[105,413,85]	-5	hSpCas9	negative selection	9724651
28748650	28748673	17	-	27869803	ASPC1	viability after 36 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	0.6213935856208829	[449]	[393,86,254]	6	hSpCas9	negative selection	9724652
28749118	28749141	17	+	27869803	ASPC1	viability after 36 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-0.32570362770983086	[501]	[282,145,32]	-3	hSpCas9	negative selection	9724653
28744111	28744134	17	-	27869803	PATU8988S	viability after 35 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	0.14146611428400435	[999]	[550,336,NaN]	1	hSpCas9	negative selection	9807097
28744116	28744139	17	-	27869803	PATU8988S	viability after 35 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	-0.24733366329107853	[413]	[126,153,NaN]	-3	hSpCas9	negative selection	9807098
28747891	28747914	17	+	27869803	PATU8988S	viability after 35 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	-0.07137440139021023	[977]	[539,208,NaN]	0	hSpCas9	negative selection	9807099
28747917	28747940	17	-	27869803	PATU8988S	viability after 35 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-1.6220863906552987	[699]	[129,52,NaN]	-8	hSpCas9	negative selection	9807100
28748650	28748673	17	-	27869803	PATU8988S	viability after 35 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	-0.5998039009925396	[453]	[186,53,NaN]	-6	hSpCas9	negative selection	9807101
28749118	28749141	17	+	27869803	PATU8988S	viability after 35 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-1.3479337384385919	[419]	[45,86,NaN]	-8	hSpCas9	negative selection	9807102
28744111	28744134	17	-	27869803	PATU8988S	viability after 31 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.3538834187569263	[999]	[344,269,NaN]	-4	hSpCas9	negative selection	9889546
28744116	28744139	17	-	27869803	PATU8988S	viability after 31 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	-0.9062876018981063	[413]	[84,91,NaN]	-7	hSpCas9	negative selection	9889547
28747891	28747914	17	+	27869803	PATU8988S	viability after 31 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.12347193910035736	[977]	[503,323,NaN]	1	hSpCas9	negative selection	9889548
28747917	28747940	17	-	27869803	PATU8988S	viability after 31 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-1.8578724103110584	[699]	[98,48,NaN]	-9	hSpCas9	negative selection	9889549
28748650	28748673	17	-	27869803	PATU8988S	viability after 31 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	-0.9858659786599897	[453]	[119,54,NaN]	-7	hSpCas9	negative selection	9889550
28749118	28749141	17	+	27869803	PATU8988S	viability after 31 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-0.486733586006451	[419]	[93,151,NaN]	-5	hSpCas9	negative selection	9889551
28744111	28744134	17	-	27869803	HPAFII	viability after 35 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-1.1293139889117971	[592]	[132,141,NaN]	-6	hSpCas9	negative selection	9971995
28744116	28744139	17	-	27869803	HPAFII	viability after 35 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	1.4197265177602112	[137]	[113,268,NaN]	8	hSpCas9	negative selection	9971996
28747891	28747914	17	+	27869803	HPAFII	viability after 35 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.7054137584035782	[530]	[284,610,NaN]	4	hSpCas9	negative selection	9971997
28747917	28747940	17	-	27869803	HPAFII	viability after 35 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	1.4533903620577537	[262]	[532,174,NaN]	8	hSpCas9	negative selection	9971998
28748650	28748673	17	-	27869803	HPAFII	viability after 35 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	-1.5539179334976068	[171]	[47,8,NaN]	-7	hSpCas9	negative selection	9971999
28749118	28749141	17	+	27869803	HPAFII	viability after 35 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-1.5217191687192946	[271]	[78,12,NaN]	-7	hSpCas9	negative selection	9972000
28744111	28744134	17	-	27869803	HPAFII	viability after 31 days	CTTGTAGTCGAAGCCAGGCATGG	TRAF4	ENSG00000076604	-0.42856535457007605	[592]	[297,191,NaN]	-3	hSpCas9	negative selection	10054444
28744116	28744139	17	-	27869803	HPAFII	viability after 31 days	AGGAACTTGTAGTCGAAGCCAGG	TRAF4	ENSG00000076604	1.2822283853762757	[137]	[162,215,NaN]	8	hSpCas9	negative selection	10054445
28747891	28747914	17	+	27869803	HPAFII	viability after 31 days	CGCTGCATCCACAGTGAGGAGGG	TRAF4	ENSG00000076604	0.5662789708679954	[530]	[245,653,NaN]	4	hSpCas9	negative selection	10054446
28747917	28747940	17	-	27869803	HPAFII	viability after 31 days	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.8956775523380848	[262]	[410,125,NaN]	6	hSpCas9	negative selection	10054447
28748650	28748673	17	-	27869803	HPAFII	viability after 31 days	TCTCACCCTGTGCTTGCAGCCGG	TRAF4	ENSG00000076604	-0.7241150863353873	[171]	[56,59,NaN]	-5	hSpCas9	negative selection	10054448
28749118	28749141	17	+	27869803	HPAFII	viability after 31 days	ACGGCGGCTACAGGAGGCCAAGG	TRAF4	ENSG00000076604	-2.0586315480256316	[271]	[50,20,NaN]	-8	hSpCas9	negative selection	10054449
28744217	28744240	17	-	28162770	P31FUJ	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.6408869430514557	[137]	[103]	-5	hSpCas9	negative selection	10256118
28747917	28747940	17	-	28162770	P31FUJ	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.6793179351663905	[694]	[509]	-5	hSpCas9	negative selection	10256119
28748082	28748105	17	-	28162770	P31FUJ	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-0.8608334270274205	[16]	[10]	-6	hSpCas9	negative selection	10256120
28748620	28748643	17	-	28162770	P31FUJ	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-3.832715046601506	[96]	[7]	-9	hSpCas9	negative selection	10256121
28744207	28744230	17	-	28162770	P31FUJ	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	-0.010409783077930695	[239]	[279]	0	hSpCas9	negative selection	10256122
28748311	28748334	17	+	28162770	P31FUJ	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	0.6972957823554651	[295]	[563]	7	hSpCas9	negative selection	10256123
28748350	28748373	17	-	28162770	P31FUJ	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-0.6349006479857247	[73]	[55]	-5	hSpCas9	negative selection	10256124
28744135	28744158	17	+	28162770	P31FUJ	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	0.2790968341170541	[53]	[76]	3	hSpCas9	negative selection	10256125
28747842	28747865	17	+	28162770	P31FUJ	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.44692700976722605	[318]	[274]	-4	hSpCas9	negative selection	10256126
28744217	28744240	17	-	28162770	TF1	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	NaN	[NaN]	[216]	1	hSpCas9	negative selection	10425484
28747917	28747940	17	-	28162770	TF1	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	NaN	[NaN]	[765]	1	hSpCas9	negative selection	10425485
28748082	28748105	17	-	28162770	TF1	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10425486
28748620	28748643	17	-	28162770	TF1	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	NaN	[NaN]	[28]	1	hSpCas9	negative selection	10425487
28744207	28744230	17	-	28162770	TF1	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	NaN	[NaN]	[204]	1	hSpCas9	negative selection	10425488
28748311	28748334	17	+	28162770	TF1	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10425489
28748350	28748373	17	-	28162770	TF1	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10425490
28744135	28744158	17	+	28162770	TF1	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	NaN	[NaN]	[51]	1	hSpCas9	negative selection	10425491
28747842	28747865	17	+	28162770	TF1	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	NaN	[NaN]	[230]	1	hSpCas9	negative selection	10425492
28744217	28744240	17	-	28162770	SKM1	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.3289616867418887	[53]	[75]	-3	hSpCas9	negative selection	10594850
28747917	28747940	17	-	28162770	SKM1	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.2178385665097855	[124]	[256]	2	hSpCas9	negative selection	10594851
28748082	28748105	17	-	28162770	SKM1	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-1.6699986045769561	[8]	[4]	-8	hSpCas9	negative selection	10594852
28748620	28748643	17	-	28162770	SKM1	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-1.641429452380185	[29]	[16]	-8	hSpCas9	negative selection	10594853
28744207	28744230	17	-	28162770	SKM1	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	0.42007308917614217	[51]	[122]	4	hSpCas9	negative selection	10594854
28748311	28748334	17	+	28162770	SKM1	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	0.4203591395470385	[40]	[96]	4	hSpCas9	negative selection	10594855
28748350	28748373	17	-	28162770	SKM1	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-1.5996092766855576	[23]	[13]	-8	hSpCas9	negative selection	10594856
28744135	28744158	17	+	28162770	SKM1	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	0.4190064014817896	[10]	[25]	4	hSpCas9	negative selection	10594857
28747842	28747865	17	+	28162770	SKM1	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.2711077063694761	[59]	[127]	2	hSpCas9	negative selection	10594858
28744217	28744240	17	-	28162770	SKM1	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.3289616867418887	[53]	[75]	-3	hSpCas9	negative selection	10764216
28747917	28747940	17	-	28162770	SKM1	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.2178385665097855	[124]	[256]	2	hSpCas9	negative selection	10764217
28748082	28748105	17	-	28162770	SKM1	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-1.6699986045769561	[8]	[4]	-8	hSpCas9	negative selection	10764218
28748620	28748643	17	-	28162770	SKM1	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-1.641429452380185	[29]	[16]	-8	hSpCas9	negative selection	10764219
28744207	28744230	17	-	28162770	SKM1	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	0.42007308917614217	[51]	[122]	4	hSpCas9	negative selection	10764220
28748311	28748334	17	+	28162770	SKM1	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	0.4203591395470385	[40]	[96]	4	hSpCas9	negative selection	10764221
28748350	28748373	17	-	28162770	SKM1	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-1.5996092766855576	[23]	[13]	-8	hSpCas9	negative selection	10764222
28744135	28744158	17	+	28162770	SKM1	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	0.4190064014817896	[10]	[25]	4	hSpCas9	negative selection	10764223
28747842	28747865	17	+	28162770	SKM1	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.2711077063694761	[59]	[127]	2	hSpCas9	negative selection	10764224
28744217	28744240	17	-	28162770	PL21	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.3758897614618282	[160]	[53]	-3	hSpCas9	negative selection	10933582
28747917	28747940	17	-	28162770	PL21	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.035373728580569086	[404]	[171]	0	hSpCas9	negative selection	10933583
28748082	28748105	17	-	28162770	PL21	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	1.318784110987939	[34]	[37]	9	hSpCas9	negative selection	10933584
28748620	28748643	17	-	28162770	PL21	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-0.3848228862318359	[80]	[26]	-3	hSpCas9	negative selection	10933585
28744207	28744230	17	-	28162770	PL21	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	0.7990413061683501	[205]	[155]	6	hSpCas9	negative selection	10933586
28748311	28748334	17	+	28162770	PL21	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	0.39836572469501563	[128]	[73]	3	hSpCas9	negative selection	10933587
28748350	28748373	17	-	28162770	PL21	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-1.7067509811191983	[59]	[7]	-8	hSpCas9	negative selection	10933588
28744135	28744158	17	+	28162770	PL21	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	-3.3848228862318366	[23]	[0]	-9	hSpCas9	negative selection	10933589
28747842	28747865	17	+	28162770	PL21	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.47697981984814436	[207]	[125]	4	hSpCas9	negative selection	10933590
28744217	28744240	17	-	28162770	P31FUJ	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.6408869430514557	[137]	[103]	-5	hSpCas9	negative selection	11102948
28747917	28747940	17	-	28162770	P31FUJ	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.6793179351663905	[694]	[509]	-5	hSpCas9	negative selection	11102949
28748082	28748105	17	-	28162770	P31FUJ	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-0.8608334270274205	[16]	[10]	-6	hSpCas9	negative selection	11102950
28748620	28748643	17	-	28162770	P31FUJ	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-3.832715046601506	[96]	[7]	-9	hSpCas9	negative selection	11102951
28744207	28744230	17	-	28162770	P31FUJ	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	-0.010409783077930695	[239]	[279]	0	hSpCas9	negative selection	11102952
28748311	28748334	17	+	28162770	P31FUJ	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	0.6972957823554651	[295]	[563]	7	hSpCas9	negative selection	11102953
28748350	28748373	17	-	28162770	P31FUJ	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-0.6349006479857247	[73]	[55]	-5	hSpCas9	negative selection	11102954
28744135	28744158	17	+	28162770	P31FUJ	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	0.2790968341170541	[53]	[76]	3	hSpCas9	negative selection	11102955
28747842	28747865	17	+	28162770	P31FUJ	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.44692700976722605	[318]	[274]	-4	hSpCas9	negative selection	11102956
28744217	28744240	17	-	28162770	OCIAML5	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	2.3540407668849612	[34]	[322]	9	hSpCas9	negative selection	11272314
28747917	28747940	17	-	28162770	OCIAML5	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.0657476737807583	[306]	[579]	0	hSpCas9	negative selection	11272315
28748082	28748105	17	-	28162770	OCIAML5	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-0.11510097669779062	[14]	[24]	-1	hSpCas9	negative selection	11272316
28748620	28748643	17	-	28162770	OCIAML5	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-2.7451513669474847	[25]	[6]	-8	hSpCas9	negative selection	11272317
28744207	28744230	17	-	28162770	OCIAML5	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	-0.2566116963251984	[136]	[206]	-2	hSpCas9	negative selection	11272318
28748311	28748334	17	+	28162770	OCIAML5	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	1.0575181339137845	[106]	[401]	8	hSpCas9	negative selection	11272319
28748350	28748373	17	-	28162770	OCIAML5	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-1.437029071585153	[41]	[27]	-7	hSpCas9	negative selection	11272320
28744135	28744158	17	+	28162770	OCIAML5	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	1.8557526776426927	[14]	[97]	9	hSpCas9	negative selection	11272321
28747842	28747865	17	+	28162770	OCIAML5	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.08234508750842628	[179]	[343]	0	hSpCas9	negative selection	11272322
28744217	28744240	17	-	28162770	EOL1	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.46998190810505347	[332]	[242]	4	hSpCas9	negative selection	11441680
28747917	28747940	17	-	28162770	EOL1	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.4004795619757141	[698]	[278]	-3	hSpCas9	negative selection	11441681
28748082	28748105	17	-	28162770	EOL1	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-0.27981072693565157	[52]	[22]	-2	hSpCas9	negative selection	11441682
28748620	28748643	17	-	28162770	EOL1	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-1.195191472703561	[112]	[25]	-7	hSpCas9	negative selection	11441683
28744207	28744230	17	-	28162770	EOL1	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	-0.3844990320200955	[445]	[179]	-3	hSpCas9	negative selection	11441684
28748311	28748334	17	+	28162770	EOL1	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	0.34627992342338665	[214]	[143]	3	hSpCas9	negative selection	11441685
28748350	28748373	17	-	28162770	EOL1	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-0.7275289250091586	[65]	[20]	-5	hSpCas9	negative selection	11441686
28744135	28744158	17	+	28162770	EOL1	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	1.6350411543755496	[32]	[53]	9	hSpCas9	negative selection	11441687
28747842	28747865	17	+	28162770	EOL1	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.2129557521794003	[340]	[154]	-2	hSpCas9	negative selection	11441688
28744217	28744240	17	-	28162770	MOLM13	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.9501255807113227	[193]	[270]	7	hSpCas9	negative selection	11611046
28747917	28747940	17	-	28162770	MOLM13	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.23477451175045128	[567]	[348]	-1	hSpCas9	negative selection	11611047
28748082	28748105	17	-	28162770	MOLM13	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-2.733744479625072	[45]	[4]	-8	hSpCas9	negative selection	11611048
28748620	28748643	17	-	28162770	MOLM13	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-4.871960621340047	[80]	[1]	-9	hSpCas9	negative selection	11611049
28744207	28744230	17	-	28162770	MOLM13	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	0.20583274263461496	[294]	[245]	1	hSpCas9	negative selection	11611050
28748311	28748334	17	+	28162770	MOLM13	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	0.6660165245033902	[196]	[225]	5	hSpCas9	negative selection	11611051
28748350	28748373	17	-	28162770	MOLM13	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-1.9381029781312584	[52]	[9]	-7	hSpCas9	negative selection	11611052
28744135	28744158	17	+	28162770	MOLM13	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	0.6671981897679855	[53]	[61]	5	hSpCas9	negative selection	11611053
28747842	28747865	17	+	28162770	MOLM13	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.18122791678212724	[393]	[322]	1	hSpCas9	negative selection	11611054
28744217	28744240	17	-	28162770	HEL	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.29741030453291767	[201]	[158]	2	hSpCas9	negative selection	11780412
28747917	28747940	17	-	28162770	HEL	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.10904275929529006	[521]	[309]	-1	hSpCas9	negative selection	11780413
28748082	28748105	17	-	28162770	HEL	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-0.35726116799964336	[47]	[23]	-3	hSpCas9	negative selection	11780414
28748620	28748643	17	-	28162770	HEL	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-2.0437616951828614	[102]	[15]	-8	hSpCas9	negative selection	11780415
28744207	28744230	17	-	28162770	HEL	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	0.8503342514087243	[251]	[290]	7	hSpCas9	negative selection	11780416
28748311	28748334	17	+	28162770	HEL	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.34988163763404556	[194]	[97]	-2	hSpCas9	negative selection	11780417
28748350	28748373	17	-	28162770	HEL	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-0.7722986672784868	[71]	[26]	-5	hSpCas9	negative selection	11780418
28744135	28744158	17	+	28162770	HEL	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	-0.23861667150102406	[34]	[18]	-2	hSpCas9	negative selection	11780419
28747842	28747865	17	+	28162770	HEL	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.23345496638524524	[278]	[151]	-2	hSpCas9	negative selection	11780420
28744217	28744240	17	-	28162770	MV411	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.3290633711901848	[169]	[113]	-2	hSpCas9	negative selection	11949778
28747917	28747940	17	-	28162770	MV411	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.09247817403616554	[342]	[270]	0	hSpCas9	negative selection	11949779
28748082	28748105	17	-	28162770	MV411	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	0.5469978326416833	[12]	[15]	5	hSpCas9	negative selection	11949780
28748620	28748643	17	-	28162770	MV411	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-1.4724545300244893	[55]	[16]	-7	hSpCas9	negative selection	11949781
28744207	28744230	17	-	28162770	MV411	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	0.7924336441862868	[182]	[266]	7	hSpCas9	negative selection	11949782
28748311	28748334	17	+	28162770	MV411	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	0.43609911480667357	[135]	[154]	4	hSpCas9	negative selection	11949783
28748350	28748373	17	-	28162770	MV411	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-0.8900659729671596	[43]	[19]	-6	hSpCas9	negative selection	11949784
28744135	28744158	17	+	28162770	MV411	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	-2.13722629945255	[46]	[8]	-8	hSpCas9	negative selection	11949785
28747842	28747865	17	+	28162770	MV411	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.21858268811059012	[201]	[197]	2	hSpCas9	negative selection	11949786
28744217	28744240	17	-	28162770	MONOMAC1	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.33729958059163445	[86]	[125]	3	hSpCas9	negative selection	12119144
28747917	28747940	17	-	28162770	MONOMAC1	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.23656521124619112	[258]	[251]	-2	hSpCas9	negative selection	12119145
28748082	28748105	17	-	28162770	MONOMAC1	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	0.2465698044160609	[24]	[33]	2	hSpCas9	negative selection	12119146
28748620	28748643	17	-	28162770	MONOMAC1	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-1.4085409522532655	[43]	[18]	-8	hSpCas9	negative selection	12119147
28744207	28744230	17	-	28162770	MONOMAC1	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	0.12123422421971941	[157]	[196]	1	hSpCas9	negative selection	12119148
28748311	28748334	17	+	28162770	MONOMAC1	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	0.6160850182169367	[106]	[187]	6	hSpCas9	negative selection	12119149
28748350	28748373	17	-	28162770	MONOMAC1	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	0.5853717178678195	[24]	[42]	6	hSpCas9	negative selection	12119150
28744135	28744158	17	+	28162770	MONOMAC1	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	0.04688873582653552	[37]	[44]	0	hSpCas9	negative selection	12119151
28747842	28747865	17	+	28162770	MONOMAC1	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	-0.24875188360370915	[141]	[136]	-2	hSpCas9	negative selection	12119152
28744217	28744240	17	-	28162770	OCIAML2	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	0.14604153520633315	[29]	[183]	1	hSpCas9	negative selection	12288510
28747917	28747940	17	-	28162770	OCIAML2	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	-0.3114312303929071	[74]	[334]	-3	hSpCas9	negative selection	12288511
28748082	28748105	17	-	28162770	OCIAML2	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	-0.5320303699063045	[5]	[22]	-4	hSpCas9	negative selection	12288512
28748620	28748643	17	-	28162770	OCIAML2	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-1.5637392296336428	[23]	[44]	-7	hSpCas9	negative selection	12288513
28744207	28744230	17	-	28162770	OCIAML2	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	-0.0016333425693299264	[40]	[226]	0	hSpCas9	negative selection	12288514
28748311	28748334	17	+	28162770	OCIAML2	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	0.7281500388723364	[21]	[201]	7	hSpCas9	negative selection	12288515
28748350	28748373	17	-	28162770	OCIAML2	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-3.0555923259633175	[8]	[5]	-9	hSpCas9	negative selection	12288516
28744135	28744158	17	+	28162770	OCIAML2	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	-1.248237403905713	[8]	[20]	-7	hSpCas9	negative selection	12288517
28747842	28747865	17	+	28162770	OCIAML2	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.12033141610043813	[39]	[240]	1	hSpCas9	negative selection	12288518
28744217	28744240	17	-	28162770	OCIAML3	viability	GGCAGGTATCGCAGAAACGGTGG	TRAF4	ENSG00000076604	-0.6751444030495686	[63]	[120]	-5	hSpCas9	negative selection	12457876
28747917	28747940	17	-	28162770	OCIAML3	viability	GACGTAGTGGCCCACTCCAGCGG	TRAF4	ENSG00000076604	0.24102573338039157	[117]	[420]	2	hSpCas9	negative selection	12457877
28748082	28748105	17	-	28162770	OCIAML3	viability	AGTGTGCAGGTAGATCACGGCGG	TRAF4	ENSG00000076604	1.1064320778169292	[3]	[25]	8	hSpCas9	negative selection	12457878
28748620	28748643	17	-	28162770	OCIAML3	viability	GAATGGGCAGAGCACCAGGGCGG	TRAF4	ENSG00000076604	-1.0090451396030071	[19]	[29]	-6	hSpCas9	negative selection	12457879
28744207	28744230	17	-	28162770	OCIAML3	viability	GCAGAAACGGTGGCCGCAGGTGG	TRAF4	ENSG00000076604	-0.6055032791619925	[62]	[124]	-4	hSpCas9	negative selection	12457880
28748311	28748334	17	+	28162770	OCIAML3	viability	GTGGTGCCCGCATGATGCGGCGG	TRAF4	ENSG00000076604	-0.5807108177107053	[53]	[108]	-4	hSpCas9	negative selection	12457881
28748350	28748373	17	-	28162770	OCIAML3	viability	GCGCTTGGGGCACTCAGAGGTGG	TRAF4	ENSG00000076604	-3.5940076403241634	[15]	[3]	-9	hSpCas9	negative selection	12457882
28744135	28744158	17	+	28162770	OCIAML3	viability	TCCTGGAGAAGCCCAAGCGACGG	TRAF4	ENSG00000076604	2.4779422015548516	[10]	[184]	9	hSpCas9	negative selection	12457883
28747842	28747865	17	+	28162770	OCIAML3	viability	GATCTACCCAGACCCGGAGCTGG	TRAF4	ENSG00000076604	0.47248777146274357	[52]	[221]	4	hSpCas9	negative selection	12457884