Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 9218
• Symbol: VAPA
• Description: VAMP associated protein A

DataSource: http://genomecrispr.dkfz.de/#!/results/VAPA

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
9914276	9914299	18	-	26472758	Jiyoye	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.5792780866561787	[211]	[106]	-4	hSpCas9	negative selection	179057
9954117	9954140	18	-	26472758	Jiyoye	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	0.5771003829481859	[95]	[107]	4	hSpCas9	negative selection	179058
9931896	9931919	18	-	26472758	Jiyoye	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-0.8470659058699144	[228]	[95]	-5	hSpCas9	negative selection	179059
9936192	9936215	18	+	26472758	Jiyoye	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	-1.1777871192152831	[38]	[12]	-7	hSpCas9	negative selection	179060
9931882	9931905	18	+	26472758	Jiyoye	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.8200583029000736	[198]	[84]	-5	hSpCas9	negative selection	179061
9914254	9914277	18	-	26472758	Jiyoye	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	-0.34330501913481437	[285]	[169]	-2	hSpCas9	negative selection	179062
9914264	9914287	18	-	26472758	Jiyoye	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	-0.41311859625922875	[195]	[110]	-3	hSpCas9	negative selection	179063
9950449	9950472	18	-	26472758	Jiyoye	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.007290107459576589	[441]	[334]	0	hSpCas9	negative selection	179064
9914298	9914321	18	-	26472758	Jiyoye	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-1.2022401629398218	[118]	[38]	-7	hSpCas9	negative selection	179065
9954140	9954163	18	-	26472758	Jiyoye	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	-1.0453368231916333	[155]	[56]	-6	hSpCas9	negative selection	179066
9914276	9914299	18	-	26472758	KBM7	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-1.1110477204780427	[937,692]	[219,135]	-7	hSpCas9	negative selection	370175
9954117	9954140	18	-	26472758	KBM7	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	-0.2319452874098225	[790,679]	[262,320]	-2	hSpCas9	negative selection	370176
9931896	9931919	18	-	26472758	KBM7	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-0.7357455353170397	[727,436]	[206,119]	-6	hSpCas9	negative selection	370177
9936192	9936215	18	+	26472758	KBM7	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	-0.3875217996308906	[164,142]	[69,41]	-4	hSpCas9	negative selection	370178
9931882	9931905	18	+	26472758	KBM7	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.9287477685411554	[607,481]	[186,85]	-6	hSpCas9	negative selection	370179
9914254	9914277	18	-	26472758	KBM7	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	0.1468496109564602	[901,432]	[370,305]	1	hSpCas9	negative selection	370180
9914264	9914287	18	-	26472758	KBM7	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	0.2377273117634986	[599,639]	[307,380]	2	hSpCas9	negative selection	370181
9950449	9950472	18	-	26472758	KBM7	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.22393045426886538	[1780,1761]	[1080,883]	2	hSpCas9	negative selection	370182
9914298	9914321	18	-	26472758	KBM7	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-0.6702346544854891	[502,331]	[85,152]	-5	hSpCas9	negative selection	370183
9954140	9954163	18	-	26472758	KBM7	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	-0.2476065877641817	[398,546]	[318,76]	-2	hSpCas9	negative selection	370184
9914276	9914299	18	-	26472758	Raji	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.031444169323717186	[435]	[98]	0	hSpCas9	negative selection	561293
9954117	9954140	18	-	26472758	Raji	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	-1.2440888351277783	[295]	[28]	-7	hSpCas9	negative selection	561294
9931896	9931919	18	-	26472758	Raji	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	0.4187423885507744	[273]	[84]	4	hSpCas9	negative selection	561295
9936192	9936215	18	+	26472758	Raji	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	0.2593866288186495	[71]	[19]	2	hSpCas9	negative selection	561296
9931882	9931905	18	+	26472758	Raji	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	1.59689925061172	[150]	[105]	9	hSpCas9	negative selection	561297
9914254	9914277	18	-	26472758	Raji	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	0.5564828707260763	[292]	[99]	5	hSpCas9	negative selection	561298
9914264	9914287	18	-	26472758	Raji	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	0.7425088308328506	[357]	[138]	7	hSpCas9	negative selection	561299
9950449	9950472	18	-	26472758	Raji	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.9040438566349673	[676]	[293]	8	hSpCas9	negative selection	561300
9914298	9914321	18	-	26472758	Raji	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	0.8528107082880019	[135]	[56]	7	hSpCas9	negative selection	561301
9954140	9954163	18	-	26472758	Raji	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	0.421242200285076	[250]	[77]	4	hSpCas9	negative selection	561302
9914276	9914299	18	-	26472758	K562	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	0.5089038073689656	[496]	[596]	4	hSpCas9	negative selection	752411
9954117	9954140	18	-	26472758	K562	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	-0.23724740648897652	[612]	[438]	-2	hSpCas9	negative selection	752412
9931896	9931919	18	-	26472758	K562	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-0.06793310763783283	[487]	[392]	0	hSpCas9	negative selection	752413
9936192	9936215	18	+	26472758	K562	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	-0.5911944544326706	[115]	[64]	-4	hSpCas9	negative selection	752414
9931882	9931905	18	+	26472758	K562	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.2201711814197696	[359]	[353]	1	hSpCas9	negative selection	752415
9914254	9914277	18	-	26472758	K562	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	0.5352980329201651	[572]	[700]	4	hSpCas9	negative selection	752416
9914264	9914287	18	-	26472758	K562	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	0.008686284627894114	[669]	[568]	0	hSpCas9	negative selection	752417
9950449	9950472	18	-	26472758	K562	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.7187903663276929	[1440]	[2001]	6	hSpCas9	negative selection	752418
9914298	9914321	18	-	26472758	K562	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-0.4190178310777942	[254]	[160]	-3	hSpCas9	negative selection	752419
9954140	9954163	18	-	26472758	K562	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	1.6580011637449037	[371]	[990]	9	hSpCas9	negative selection	752420
9945025	9945048	18	+	26627737	DLD1	viability	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	1.3471786435954922	[356]	[415,246,199]	9	hSpCas9	negative selection	802205
9945025	9945048	18	+	26627737	GBM cells	viability after 5 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.02931051214136049	[369]	[195,208]	0	hSpCas9	negative selection	884520
9945025	9945048	18	+	26627737	GBM cells	viability after 13 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	-0.06569775459751814	[369]	[166,211]	-1	hSpCas9	negative selection	966835
9945025	9945048	18	+	26627737	GBM cells	viability after 21 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.21283157484836157	[369]	[221,242]	2	hSpCas9	negative selection	1049150
9945025	9945048	18	+	26627737	RPE1	viability after 9 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	2.026297053963132	[582]	[715,778]	8	hSpCas9	negative selection	1131465
9945025	9945048	18	+	26627737	RPE1	viability after 12 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	1.8599571318460484	[582]	[672,457]	8	hSpCas9	negative selection	1213780
9945025	9945048	18	+	26627737	RPE1	viability after 15 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	2.2239547470954166	[582]	[941,604]	9	hSpCas9	negative selection	1296095
9945025	9945048	18	+	26627737	RPE1	viability after 18 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	1.3475904435974513	[582]	[440,356]	7	hSpCas9	negative selection	1378410
9945025	9945048	18	+	26627737	HeLa	viability after 8 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.05020049682420902	[715]	[472,310,223]	0	hSpCas9	negative selection	1460725
9945025	9945048	18	+	26627737	HeLa	viability after 12 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	-0.004883700381003608	[715]	[215,326,335]	0	hSpCas9	negative selection	1543040
9945025	9945048	18	+	26627737	HeLa	viability after 15 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.2098470822184445	[715]	[363,285,362]	1	hSpCas9	negative selection	1625355
9945025	9945048	18	+	26627737	HeLa	viability after 18 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.20878079104148017	[715]	[241,238,362]	1	hSpCas9	negative selection	1707670
9945025	9945048	18	+	26627737	HCT116	viability after 6 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	-1.7984800498320779	[906]	[98,8]	-7	hSpCas9	negative selection	1789985
9945025	9945048	18	+	26627737	HCT116	viability after 8 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.3297464957978413	[462]	[331,381,248]	3	hSpCas9	negative selection	1872300
9945025	9945048	18	+	26627737	HCT116	viability after 9 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.17697173079318596	[906]	[456,128]	1	hSpCas9	negative selection	1954615
9945025	9945048	18	+	26627737	HCT116	viability after 12 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.06848592567661915	[462]	[225,254,286]	0	hSpCas9	negative selection	2036930
9945025	9945048	18	+	26627737	HCT116	viability after 15 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.2943283937648238	[462]	[267,280,420]	3	hSpCas9	negative selection	2119245
9945025	9945048	18	+	26627737	HCT116	viability after 18 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.10632355135121085	[462]	[319,215,185]	0	hSpCas9	negative selection	2201560
9932829	9932852	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATAAGCCACCGCGCCCGG	VAPA	ENSG00000101558	-0.05390791448994714	[42,66]	[1,20]	0	dCas9-VP64	positive selection	2476071
9932829	9932852	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATAAGCCACCGCGCCCGG	VAPA	ENSG00000101558	1.4890732755613398	[69,66]	[18,103]	8	dCas9-VP64	positive selection	2571326
9931922	9931945	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAGTGGAATTATTGACCCAGGG	VAPA	ENSG00000101558	0.50849550510001	[2,3]	[2,5]	9	hSpCas9	positive selection	3031572
9914276	9914299	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.07088632862481073	[3,3]	[4,1]	-1	hSpCas9	positive selection	3031573
9931812	9931835	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGTGACTACATCTGTGAAGGG	VAPA	ENSG00000101558	-0.15732629969289902	[2,3]	[2,2]	-2	hSpCas9	positive selection	3031574
9936121	9936144	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCATTCGGATCATAGTCAAAGGG	VAPA	ENSG00000101558	0.056408788730491335	[3,3]	[3,2]	1	hSpCas9	positive selection	3031575
9931922	9931945	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAGTGGAATTATTGACCCAGGG	VAPA	ENSG00000101558	0.15510265520719047	[2,2]	[2,1]	2	hSpCas9	positive selection	3099430
9914276	9914299	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	0.7259564137055237	[3,3]	[4,4]	9	hSpCas9	positive selection	3099431
9931812	9931835	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGTGACTACATCTGTGAAGGG	VAPA	ENSG00000101558	0.16210968047976612	[2,2]	[2,1]	3	hSpCas9	positive selection	3099432
9936121	9936144	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCATTCGGATCATAGTCAAAGGG	VAPA	ENSG00000101558	-0.21201720909891522	[3,3]	[1,1]	-3	hSpCas9	positive selection	3099433
9931941	9931964		+	24336571	A375	resistance to PLX after 7 days	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	-0.3082744132759204	[24,20]	[20,15]	-8	hSpCas9	positive selection	3154831
9936183	9936206		+	24336571	A375	resistance to PLX after 7 days	TCCACCAAACACTTCAGATATGG	VAPA	ENSG00000101558	0.12906441397712298	[8,5]	[7,8]	4	hSpCas9	positive selection	3154832
9931941	9931964		+	24336571	A375	resistance to PLX after 14 days	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	-0.8885223295042999	[24,16]	[4,3]	-9	hSpCas9	positive selection	3212624
9936183	9936206		+	24336571	A375	resistance to PLX after 14 days	TCCACCAAACACTTCAGATATGG	VAPA	ENSG00000101558	0.9738458182932656	[3,4]	[3,3]	7	hSpCas9	positive selection	3212625
9931941	9931964		+	24336571	A375	viability after 7 days	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.6379187018871986	[14]	[24,20]	8	hSpCas9	negative selection	3270417
9936183	9936206		+	24336571	A375	viability after 7 days	TCCACCAAACACTTCAGATATGG	VAPA	ENSG00000101558	0.5424920319325233	[4]	[8,5]	7	hSpCas9	negative selection	3270418
9931941	9931964		+	24336571	A375	viability after 14 days	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.5067972393224232	[14]	[24,16]	6	hSpCas9	negative selection	3328210
9936183	9936206		+	24336571	A375	viability after 14 days	TCCACCAAACACTTCAGATATGG	VAPA	ENSG00000101558	-0.12824947792269503	[4]	[3,4]	-1	hSpCas9	negative selection	3328211
9931941	9931964	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.009398698002249677	[151,151]	[0,0]	0	hSpCas9	positive selection	3400772
9937020	9937043	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	-1.0187981938284023	[309,309]	[0,0]	-6	hSpCas9	positive selection	3400773
9936994	9937017	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.4499712893882311	[111,111]	[0,0]	2	hSpCas9	positive selection	3400774
9931921	9931944	18	+	26780180	HT29	viability (Avana library 4 designs)	ACAGTGGAATTATTGACCCAGGG	VAPA	ENSG00000101558	1.39558825408385	[]	[]	5	hSpCas9	negative selection	3470778
9914276	9914299	18	-	26780180	HT29	viability (Avana library 4 designs)	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.116413734889627	[]	[]	-2	hSpCas9	negative selection	3470779
9931812	9931835	18	-	26780180	HT29	viability (Avana library 4 designs)	GTAGTGACTACATCTGTGAAGGG	VAPA	ENSG00000101558	0.264115444749403	[]	[]	0	hSpCas9	negative selection	3470780
9936121	9936144	18	-	26780180	HT29	viability (Avana library 4 designs)	TCATTCGGATCATAGTCAAAGGG	VAPA	ENSG00000101558	1.2891258111044	[]	[]	5	hSpCas9	negative selection	3470781
9914276	9914299	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-5.61367544696333	[]	[]	-6	hSpCas9	negative selection	3577072
9936121	9936144	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCATTCGGATCATAGTCAAAGGG	VAPA	ENSG00000101558	-8.5612211410886	[]	[]	-7	hSpCas9	negative selection	3577073
9931921	9931944	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGTGGAATTATTGACCCAGGG	VAPA	ENSG00000101558	-4.62269698591964	[]	[]	-5	hSpCas9	negative selection	3577074
9931812	9931835	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGTGACTACATCTGTGAAGGG	VAPA	ENSG00000101558	-4.77333839204979	[]	[]	-5	hSpCas9	negative selection	3577075
9931882	9931905	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-2.8144695588046	[]	[]	-3	hSpCas9	negative selection	3577076
9914311	9914334	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGAATTTGAGGTCTGTGGGCGG	VAPA	ENSG00000101558	3.95896250583513	[]	[]	6	hSpCas9	negative selection	3577077
9914276	9914299	18	-	26780180	A375	viability (Avana lentiGuide)	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	4.48714814476548	[]	[]	4	hSpCas9	negative selection	3685731
9936121	9936144	18	-	26780180	A375	viability (Avana lentiGuide)	TCATTCGGATCATAGTCAAAGGG	VAPA	ENSG00000101558	3.30654980855576	[]	[]	3	hSpCas9	negative selection	3685732
9931921	9931944	18	+	26780180	A375	viability (Avana lentiGuide)	ACAGTGGAATTATTGACCCAGGG	VAPA	ENSG00000101558	1.13856438126524	[]	[]	1	hSpCas9	negative selection	3685733
9931812	9931835	18	-	26780180	A375	viability (Avana lentiGuide)	GTAGTGACTACATCTGTGAAGGG	VAPA	ENSG00000101558	2.50922249998256	[]	[]	2	hSpCas9	negative selection	3685734
9931882	9931905	18	+	26780180	A375	viability (Avana lentiGuide)	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	8.58644331553726	[]	[]	6	hSpCas9	negative selection	3685735
9914311	9914334	18	-	26780180	A375	viability (Avana lentiGuide)	TTGAATTTGAGGTCTGTGGGCGG	VAPA	ENSG00000101558	0.48173451364223	[]	[]	0	hSpCas9	negative selection	3685736
9914276	9914299	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.3567969066747779	[5]	[4,3]	-5	hSpCas9	positive selection	3794338
9936121	9936144	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATTCGGATCATAGTCAAAGGG	VAPA	ENSG00000101558	-0.7191528030229933	[7]	[5,2]	-8	hSpCas9	positive selection	3794339
9931921	9931944	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGTGGAATTATTGACCCAGGG	VAPA	ENSG00000101558	-0.6906603568410028	[5]	[3,1]	-7	hSpCas9	positive selection	3794340
9931812	9931835	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGTGACTACATCTGTGAAGGG	VAPA	ENSG00000101558	-0.17580764216186656	[5]	[5,3]	-3	hSpCas9	positive selection	3794341
9931882	9931905	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.6135983821619129	[4]	[3,1]	-7	hSpCas9	positive selection	3794342
9914311	9914334	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGAATTTGAGGTCTGTGGGCGG	VAPA	ENSG00000101558	0.16606273727656884	[5]	[6,5]	4	hSpCas9	positive selection	3794343
9914276	9914299	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.299274403926158	[5]	[3,3]	-4	hSpCas9	positive selection	3902945
9936121	9936144	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATTCGGATCATAGTCAAAGGG	VAPA	ENSG00000101558	-0.6451257525835483	[5]	[2,2]	-7	hSpCas9	positive selection	3902946
9931921	9931944	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGTGGAATTATTGACCCAGGG	VAPA	ENSG00000101558	-0.9046055519843834	[5]	[1,2]	-8	hSpCas9	positive selection	3902947
9931812	9931835	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGTGACTACATCTGTGAAGGG	VAPA	ENSG00000101558	0.015059592530187557	[4]	[3,5]	0	hSpCas9	positive selection	3902948
9931882	9931905	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.055108928397589574	[5]	[3,5]	-1	hSpCas9	positive selection	3902949
9914311	9914334	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGAATTTGAGGTCTGTGGGCGG	VAPA	ENSG00000101558	0.1821988004384115	[6]	[6,6]	4	hSpCas9	positive selection	3902950
9944992	9945015	18	+	26780180	A375	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	1.10459652685802	[]	[]	5	hSpCas9	negative selection	4011296
9936994	9937017	18	+	26780180	A375	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.440130469888699	[]	[]	1	hSpCas9	negative selection	4011297
9931941	9931964	18	+	26780180	A375	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.654770848134363	[]	[]	2	hSpCas9	negative selection	4011298
9944997	9945020	18	-	26780180	A375	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	1.11352418999653	[]	[]	5	hSpCas9	negative selection	4011299
9931882	9931905	18	+	26780180	A375	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	1.22652083588211	[]	[]	6	hSpCas9	negative selection	4011300
9937020	9937043	18	-	26780180	A375	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	1.04246351229581	[]	[]	5	hSpCas9	negative selection	4011301
9944992	9945015	18	+	26780180	HT29	viability (GeCKOv2 library)	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.74120767880783	[]	[]	3	hSpCas9	negative selection	4119262
9936994	9937017	18	+	26780180	HT29	viability (GeCKOv2 library)	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	1.17851920539826	[]	[]	6	hSpCas9	negative selection	4119263
9931941	9931964	18	+	26780180	HT29	viability (GeCKOv2 library)	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.639879607894187	[]	[]	2	hSpCas9	negative selection	4119264
9944997	9945020	18	-	26780180	HT29	viability (GeCKOv2 library)	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	1.95068802616796	[]	[]	9	hSpCas9	negative selection	4119265
9931882	9931905	18	+	26780180	HT29	viability (GeCKOv2 library)	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	1.47743906303007	[]	[]	7	hSpCas9	negative selection	4119266
9937020	9937043	18	-	26780180	HT29	viability (GeCKOv2 library)	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.937778622754712	[]	[]	4	hSpCas9	negative selection	4119267
9931941	9931964	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	-0.14976167308055577	[4]	[2,2]	-4	hSpCas9	positive selection	4181565
9936183	9936206	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCACCAAACACTTCAGATATGG	VAPA	ENSG00000101558	-0.3773098217087236	[3]	[1,1]	-7	hSpCas9	positive selection	4181566
9931941	9931964	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	1.0986882504151032	[4]	[3,0,4,4]	8	hSpCas9	positive selection	4245587
9936183	9936206	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCACCAAACACTTCAGATATGG	VAPA	ENSG00000101558	-0.3875911459258495	[4]	[0,2,1,0]	-5	hSpCas9	positive selection	4245588
9944997	9945020	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	-0.05988534182748481	[2]	[2,1]	-1	hSpCas9	positive selection	4307136
9944992	9945015	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	-0.3194539920879987	[2]	[2,0]	-6	hSpCas9	positive selection	4307137
9931882	9931905	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.16949171482165334	[3]	[2,1]	-3	hSpCas9	positive selection	4307138
9931941	9931964	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.35024246031789863	[2]	[2,2]	7	hSpCas9	positive selection	4371383
9937020	9937043	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.29765961258331364	[3]	[3,2]	6	hSpCas9	positive selection	4371384
9936994	9937017	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.16526991844752847	[2]	[2,1]	3	hSpCas9	positive selection	4371385
9931854	9931876	18	-	27760321	OCIAML3	viability	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	-0.0402442208502658	[291,224]	[159,240]	0	hSpCas9	negative selection	4453017
9931895	9931917	18	+	27760321	OCIAML3	viability	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	-0.3154221765625803	[865,697]	[394,610]	-3	hSpCas9	negative selection	4453018
9936122	9936144	18	-	27760321	OCIAML3	viability	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	0.3142194979129851	[183,147]	[153,168]	3	hSpCas9	negative selection	4453019
9944919	9944941	18	+	27760321	OCIAML3	viability	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	0.8038256299758183	[274,266]	[276,492]	8	hSpCas9	negative selection	4453020
9944933	9944955	18	-	27760321	OCIAML3	viability	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	0.20291851770257519	[985,861]	[733,954]	2	hSpCas9	negative selection	4453021
9944948	9944970	18	-	27760321	OCIAML3	viability	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	0.5494600906774473	[293,283]	[287,387]	6	hSpCas9	negative selection	4453022
9944993	9945015	18	-	27760321	OCIAML3	viability	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	-0.537575417854863	[538,501]	[214,365]	-5	hSpCas9	negative selection	4453023
9950383	9950405	18	+	27760321	OCIAML3	viability	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	-3.9638376558750794	[27,12]	[0,0]	-9	hSpCas9	negative selection	4453024
9950485	9950507	18	+	27760321	OCIAML3	viability	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	-0.3351109261689489	[25,27]	[28,0]	-4	hSpCas9	negative selection	4453025
9931854	9931876	18	-	27760321	OCIAML2	viability	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	-0.7499499214885884	[291,224]	[122,123]	-7	hSpCas9	negative selection	4536480
9931895	9931917	18	+	27760321	OCIAML2	viability	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	-0.8396902924827832	[865,697]	[316,396]	-7	hSpCas9	negative selection	4536481
9936122	9936144	18	-	27760321	OCIAML2	viability	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	0.2655762363159051	[183,147]	[125,205]	3	hSpCas9	negative selection	4536482
9944919	9944941	18	+	27760321	OCIAML2	viability	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	0.17423912784390294	[274,266]	[243,252]	2	hSpCas9	negative selection	4536483
9944933	9944955	18	-	27760321	OCIAML2	viability	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	0.06525418106639624	[985,861]	[586,1034]	0	hSpCas9	negative selection	4536484
9944948	9944970	18	-	27760321	OCIAML2	viability	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	-0.07629034884420927	[293,283]	[156,307]	-1	hSpCas9	negative selection	4536485
9944993	9945015	18	-	27760321	OCIAML2	viability	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	0.3067572664094624	[538,501]	[476,578]	4	hSpCas9	negative selection	4536486
9950383	9950405	18	+	27760321	OCIAML2	viability	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	-1.7245737523316462	[27,12]	[0,9]	-9	hSpCas9	negative selection	4536487
9950485	9950507	18	+	27760321	OCIAML2	viability	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	1.0837958844999571	[25,27]	[43,49]	9	hSpCas9	negative selection	4536488
9931854	9931876	18	-	27760321	MV411	viability	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	-0.014954775117333896	[291,224]	[147,196]	0	hSpCas9	negative selection	4619943
9931895	9931917	18	+	27760321	MV411	viability	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	0.037355467820225585	[865,697]	[343,800]	0	hSpCas9	negative selection	4619944
9936122	9936144	18	-	27760321	MV411	viability	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	-1.2893788645820903	[183,147]	[2,106]	-7	hSpCas9	negative selection	4619945
9944919	9944941	18	+	27760321	MV411	viability	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	2.5000567108102607	[274,266]	[1458,344]	9	hSpCas9	negative selection	4619946
9944933	9944955	18	-	27760321	MV411	viability	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	0.4747417296147276	[985,861]	[440,1452]	3	hSpCas9	negative selection	4619947
9944948	9944970	18	-	27760321	MV411	viability	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	-0.6527961644446136	[293,283]	[33,252]	-4	hSpCas9	negative selection	4619948
9944993	9945015	18	-	27760321	MV411	viability	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	-0.5436451344896152	[538,501]	[144,371]	-4	hSpCas9	negative selection	4619949
9950383	9950405	18	+	27760321	MV411	viability	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	-3.7187590869603975	[27,12]	[0,0]	-9	hSpCas9	negative selection	4619950
9950485	9950507	18	+	27760321	MV411	viability	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	-2.399614116491713	[25,27]	[0,6]	-8	hSpCas9	negative selection	4619951
9931854	9931876	18	-	27760321	HL60	viability	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	-0.10813877072718014	[291,224]	[176,212]	-1	hSpCas9	negative selection	4703406
9931895	9931917	18	+	27760321	HL60	viability	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	-0.5746463798610215	[865,697]	[394,459]	-6	hSpCas9	negative selection	4703407
9936122	9936144	18	-	27760321	HL60	viability	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	0.3877869246274164	[183,147]	[206,143]	5	hSpCas9	negative selection	4703408
9944919	9944941	18	+	27760321	HL60	viability	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	0.3483201974207875	[274,266]	[295,267]	4	hSpCas9	negative selection	4703409
9944933	9944955	18	-	27760321	HL60	viability	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	-0.0442649224604561	[985,861]	[791,664]	0	hSpCas9	negative selection	4703410
9944948	9944970	18	-	27760321	HL60	viability	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	-0.0984475274970057	[293,283]	[300,135]	-1	hSpCas9	negative selection	4703411
9944993	9945015	18	-	27760321	HL60	viability	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	0.2724335087117325	[538,501]	[438,592]	3	hSpCas9	negative selection	4703412
9950383	9950405	18	+	27760321	HL60	viability	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	-2.7302793636252307	[27,12]	[0,3]	-9	hSpCas9	negative selection	4703413
9950485	9950507	18	+	27760321	HL60	viability	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	-0.5069213700746902	[25,27]	[2,28]	-5	hSpCas9	negative selection	4703414
9931854	9931876	18	-	27760321	HT1080	viability	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	-2.4530481016570347	[224,175]	[26,0]	-7	hSpCas9	negative selection	4786869
9931895	9931917	18	+	27760321	HT1080	viability	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	-2.418251565250456	[697,544]	[31,61]	-7	hSpCas9	negative selection	4786870
9936122	9936144	18	-	27760321	HT1080	viability	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	-1.4584845409271106	[147,115]	[0,38]	-5	hSpCas9	negative selection	4786871
9944919	9944941	18	+	27760321	HT1080	viability	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	1.5763632344860246	[266,208]	[404,148]	8	hSpCas9	negative selection	4786872
9944933	9944955	18	-	27760321	HT1080	viability	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	-0.3575600444749253	[861,672]	[230,246]	-2	hSpCas9	negative selection	4786873
9944948	9944970	18	-	27760321	HT1080	viability	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	-0.7577558661210128	[283,221]	[61,56]	-3	hSpCas9	negative selection	4786874
9944993	9945015	18	-	27760321	HT1080	viability	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	0.6453979164805375	[501,391]	[289,265]	3	hSpCas9	negative selection	4786875
9950383	9950405	18	+	27760321	HT1080	viability	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	0.07422753827327	[12,9]	[0,8]	0	hSpCas9	negative selection	4786876
9950485	9950507	18	+	27760321	HT1080	viability	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	-3.3166380037395125	[27,21]	[0,0]	-7	hSpCas9	negative selection	4786877
9931854	9931876	18	-	27760321	HT29	viability after 7 days	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	0.4974898370322657	[224,175]	[352,186,543]	7	hSpCas9	negative selection	4870332
9931895	9931917	18	+	27760321	HT29	viability after 7 days	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	0.520135459762249	[697,544]	[1483,903,1097]	7	hSpCas9	negative selection	4870333
9936122	9936144	18	-	27760321	HT29	viability after 7 days	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	-0.49495199227147557	[147,115]	[191,77,101]	-6	hSpCas9	negative selection	4870334
9944919	9944941	18	+	27760321	HT29	viability after 7 days	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	0.3617306911271676	[266,208]	[457,353,376]	5	hSpCas9	negative selection	4870335
9944933	9944955	18	-	27760321	HT29	viability after 7 days	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	0.4791765023209704	[861,672]	[1336,1559,1226]	7	hSpCas9	negative selection	4870336
9944948	9944970	18	-	27760321	HT29	viability after 7 days	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	-0.19749343464649505	[283,221]	[324,197,331]	-3	hSpCas9	negative selection	4870337
9944993	9945015	18	-	27760321	HT29	viability after 7 days	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	-0.008567443944078046	[501,391]	[449,678,566]	0	hSpCas9	negative selection	4870338
9950383	9950405	18	+	27760321	HT29	viability after 7 days	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	-0.7607659862907612	[12,9]	[26,0,0]	-8	hSpCas9	negative selection	4870339
9950485	9950507	18	+	27760321	HT29	viability after 7 days	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	-0.137176971538151	[27,21]	[28,8,48]	-2	hSpCas9	negative selection	4870340
9931854	9931876	18	-	27760321	HT29	viability after 25 days	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	0.3072789954891447	[224,175]	[181,370,305]	3	hSpCas9	negative selection	4953795
9931895	9931917	18	+	27760321	HT29	viability after 25 days	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	0.878201618625337	[697,544]	[1038,1573,1319]	8	hSpCas9	negative selection	4953796
9936122	9936144	18	-	27760321	HT29	viability after 25 days	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	0.4306347252619547	[147,115]	[172,189,253]	5	hSpCas9	negative selection	4953797
9944919	9944941	18	+	27760321	HT29	viability after 25 days	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	0.7204466187497329	[266,208]	[413,433,503]	7	hSpCas9	negative selection	4953798
9944933	9944955	18	-	27760321	HT29	viability after 25 days	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	0.24885957031991413	[861,672]	[847,1078,1229]	2	hSpCas9	negative selection	4953799
9944948	9944970	18	-	27760321	HT29	viability after 25 days	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	0.07296891837030178	[283,221]	[325,311,268]	0	hSpCas9	negative selection	4953800
9944993	9945015	18	-	27760321	HT29	viability after 25 days	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	-0.0003670863039378358	[501,391]	[390,610,539]	0	hSpCas9	negative selection	4953801
9950383	9950405	18	+	27760321	HT29	viability after 25 days	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	0.3907979390343641	[12,9]	[35,0,12]	4	hSpCas9	negative selection	4953802
9950485	9950507	18	+	27760321	HT29	viability after 25 days	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	-0.2031900163611886	[27,21]	[12,38,22]	-2	hSpCas9	negative selection	4953803
9931854	9931876	18	-	27760321	HT29	viability after 22 days	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	0.04327359545979159	[224,175]	[208,314,192]	0	hSpCas9	negative selection	5037258
9931895	9931917	18	+	27760321	HT29	viability after 22 days	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	1.0112455169254855	[697,544]	[1404,1478,1461]	9	hSpCas9	negative selection	5037259
9936122	9936144	18	-	27760321	HT29	viability after 22 days	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	0.2803440605978711	[147,115]	[118,244,193]	3	hSpCas9	negative selection	5037260
9944919	9944941	18	+	27760321	HT29	viability after 22 days	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	0.6878980890713322	[266,208]	[581,318,424]	7	hSpCas9	negative selection	5037261
9944933	9944955	18	-	27760321	HT29	viability after 22 days	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	0.5376333985725723	[861,672]	[1043,1169,1659]	6	hSpCas9	negative selection	5037262
9944948	9944970	18	-	27760321	HT29	viability after 22 days	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	0.3365643691203387	[283,221]	[338,389,379]	3	hSpCas9	negative selection	5037263
9944993	9945015	18	-	27760321	HT29	viability after 22 days	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	0.4097550591821995	[501,391]	[622,669,768]	4	hSpCas9	negative selection	5037264
9950383	9950405	18	+	27760321	HT29	viability after 22 days	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	-0.6234156447151049	[12,9]	[0,23,0]	-5	hSpCas9	negative selection	5037265
9950485	9950507	18	+	27760321	HT29	viability after 22 days	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	-1.2353066921107438	[27,21]	[5,19,10]	-7	hSpCas9	negative selection	5037266
9931854	9931876	18	-	27760321	HT29	viability after 19 days	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	-0.14335731347582248	[224,175]	[150,234,229]	-1	hSpCas9	negative selection	5120721
9931895	9931917	18	+	27760321	HT29	viability after 19 days	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	0.72500298528719	[697,544]	[1135,1212,1170]	7	hSpCas9	negative selection	5120722
9936122	9936144	18	-	27760321	HT29	viability after 19 days	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	0.5456681988448066	[147,115]	[185,290,181]	5	hSpCas9	negative selection	5120723
9944919	9944941	18	+	27760321	HT29	viability after 19 days	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	0.21372158206461211	[266,208]	[429,215,312]	2	hSpCas9	negative selection	5120724
9944933	9944955	18	-	27760321	HT29	viability after 19 days	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	0.44682196453160716	[861,672]	[1285,1411,910]	4	hSpCas9	negative selection	5120725
9944948	9944970	18	-	27760321	HT29	viability after 19 days	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	0.36705717772629076	[283,221]	[304,185,611]	3	hSpCas9	negative selection	5120726
9944993	9945015	18	-	27760321	HT29	viability after 19 days	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	0.37264488597949635	[501,391]	[475,617,863]	3	hSpCas9	negative selection	5120727
9950383	9950405	18	+	27760321	HT29	viability after 19 days	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	0.07738642000716389	[12,9]	[4,30,4]	0	hSpCas9	negative selection	5120728
9950485	9950507	18	+	27760321	HT29	viability after 19 days	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	0.6061605531851137	[27,21]	[88,46,0]	6	hSpCas9	negative selection	5120729
9931854	9931876	18	-	27760321	HT29	viability after 16 days	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	0.2642115097365758	[224,175]	[233,151,421]	3	hSpCas9	negative selection	5204184
9931895	9931917	18	+	27760321	HT29	viability after 16 days	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	0.6454139758511226	[697,544]	[1287,924,1072]	7	hSpCas9	negative selection	5204185
9936122	9936144	18	-	27760321	HT29	viability after 16 days	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	-0.03959552230721419	[147,115]	[171,59,203]	0	hSpCas9	negative selection	5204186
9944919	9944941	18	+	27760321	HT29	viability after 16 days	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	0.9605875698161905	[266,208]	[586,605,365]	9	hSpCas9	negative selection	5204187
9944933	9944955	18	-	27760321	HT29	viability after 16 days	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	0.506034369469589	[861,672]	[1123,1380,1139]	6	hSpCas9	negative selection	5204188
9944948	9944970	18	-	27760321	HT29	viability after 16 days	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	0.2595714530366828	[283,221]	[255,406,343]	3	hSpCas9	negative selection	5204189
9944993	9945015	18	-	27760321	HT29	viability after 16 days	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	-0.012968760129400625	[501,391]	[431,642,401]	0	hSpCas9	negative selection	5204190
9950383	9950405	18	+	27760321	HT29	viability after 16 days	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	-1.339344071105149	[12,9]	[11,0,2]	-7	hSpCas9	negative selection	5204191
9950485	9950507	18	+	27760321	HT29	viability after 16 days	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	0.9441140355669182	[27,21]	[60,98,0]	9	hSpCas9	negative selection	5204192
9931854	9931876	18	-	27760321	HT29	viability after 13 days	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	0.0457117503786425	[224,175]	[321,240,161]	0	hSpCas9	negative selection	5287647
9931895	9931917	18	+	27760321	HT29	viability after 13 days	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	0.6790079372286928	[697,544]	[1351,998,1113]	8	hSpCas9	negative selection	5287648
9936122	9936144	18	-	27760321	HT29	viability after 13 days	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	-0.05871303204528422	[147,115]	[67,117,248]	0	hSpCas9	negative selection	5287649
9944919	9944941	18	+	27760321	HT29	viability after 13 days	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	0.42801216651469287	[266,208]	[215,477,417]	5	hSpCas9	negative selection	5287650
9944933	9944955	18	-	27760321	HT29	viability after 13 days	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	0.765951391246575	[861,672]	[1136,2062,1352]	8	hSpCas9	negative selection	5287651
9944948	9944970	18	-	27760321	HT29	viability after 13 days	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	0.48508575419146654	[283,221]	[320,454,453]	6	hSpCas9	negative selection	5287652
9944993	9945015	18	-	27760321	HT29	viability after 13 days	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	0.10220087772061637	[501,391]	[564,550,553]	1	hSpCas9	negative selection	5287653
9950383	9950405	18	+	27760321	HT29	viability after 13 days	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	0.6893809649576026	[12,9]	[51,0,11]	8	hSpCas9	negative selection	5287654
9950485	9950507	18	+	27760321	HT29	viability after 13 days	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	0.7992532355111228	[27,21]	[49,25,73]	9	hSpCas9	negative selection	5287655
9931854	9931876	18	-	27760321	HT29	viability after 10 days	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	-0.3771917356589908	[224,175]	[157,282,140]	-5	hSpCas9	negative selection	5371110
9931895	9931917	18	+	27760321	HT29	viability after 10 days	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	0.4125455086149905	[697,544]	[1329,1050,724]	5	hSpCas9	negative selection	5371111
9936122	9936144	18	-	27760321	HT29	viability after 10 days	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	-1.1145374663067558	[147,115]	[58,115,54]	-8	hSpCas9	negative selection	5371112
9944919	9944941	18	+	27760321	HT29	viability after 10 days	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	0.33262641360306117	[266,208]	[335,415,371]	4	hSpCas9	negative selection	5371113
9944933	9944955	18	-	27760321	HT29	viability after 10 days	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	0.740967838944314	[861,672]	[1380,1870,1560]	8	hSpCas9	negative selection	5371114
9944948	9944970	18	-	27760321	HT29	viability after 10 days	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	0.21406311260249555	[283,221]	[224,343,525]	3	hSpCas9	negative selection	5371115
9944993	9945015	18	-	27760321	HT29	viability after 10 days	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	-0.005394107632819001	[501,391]	[462,536,664]	0	hSpCas9	negative selection	5371116
9950383	9950405	18	+	27760321	HT29	viability after 10 days	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	0.9698299287094181	[12,9]	[30,0,50]	9	hSpCas9	negative selection	5371117
9950485	9950507	18	+	27760321	HT29	viability after 10 days	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	0.11103591343802544	[27,21]	[11,19,67]	1	hSpCas9	negative selection	5371118
9931854	9931876	18	-	27760321	MOLM13	viability	AACACACTTTTCTATCCGATGG	VAPA	ENSG00000101558	0.03005421632106664	[291,224]	[82,202]	0	hSpCas9	negative selection	5454573
9931895	9931917	18	+	27760321	MOLM13	viability	ACCTCGCCGGTACTGTGTGAGG	VAPA	ENSG00000101558	-0.2115205435319487	[865,697]	[500,274]	-1	hSpCas9	negative selection	5454574
9936122	9936144	18	-	27760321	MOLM13	viability	TCATTCGGATCATAGTCAAAGG	VAPA	ENSG00000101558	1.5485945572080873	[183,147]	[353,202]	9	hSpCas9	negative selection	5454575
9944919	9944941	18	+	27760321	MOLM13	viability	CTCAGGGTATAACTCCACCAGG	VAPA	ENSG00000101558	0.39753412037836827	[274,266]	[331,90]	2	hSpCas9	negative selection	5454576
9944933	9944955	18	-	27760321	MOLM13	viability	CAGTCGGAGCATTCCCTGGTGG	VAPA	ENSG00000101558	0.44031652092513895	[985,861]	[768,651]	3	hSpCas9	negative selection	5454577
9944948	9944970	18	-	27760321	MOLM13	viability	TGCTCATTGAAGTGACAGTCGG	VAPA	ENSG00000101558	0.9351587567212629	[293,283]	[468,178]	6	hSpCas9	negative selection	5454578
9944993	9945015	18	-	27760321	MOLM13	viability	CCTTCGTGTGATAACTGGCAGG	VAPA	ENSG00000101558	-0.4872986444180152	[538,501]	[396,49]	-3	hSpCas9	negative selection	5454579
9950383	9950405	18	+	27760321	MOLM13	viability	TTTGTAATGCAGAATGATATGG	VAPA	ENSG00000101558	-3.492702274132802	[27,12]	[0,0]	-9	hSpCas9	negative selection	5454580
9950485	9950507	18	+	27760321	MOLM13	viability	ACCGAAACAAGGAAACTAATGG	VAPA	ENSG00000101558	1.8063028086189186	[25,27]	[4,94]	9	hSpCas9	negative selection	5454581
9913988	9914011	18	+	27661255	K562	viability	GCACGCAGAGGCCGTCACGTGGG	VAPA	ENSG00000101558	0.016062452377027192	[1184,1045]	[996,822]	0	dCas9-KRAB	negative selection	5522039
9913997	9914020	18	+	27661255	K562	viability	GGCCGTCACGTGGGTCGCCGAGG	VAPA	ENSG00000101558	-0.05540327559781	[385,387]	[243,342]	-2	dCas9-KRAB	negative selection	5522040
9914726	9914749	18	+	27661255	K562	viability	GTGGGCGGCTGGGCACCCGAGGG	VAPA	ENSG00000101558	-0.066714477018194	[976,941]	[768,700]	-3	dCas9-KRAB	negative selection	5522041
9914462	9914485	18	-	27661255	K562	viability	GAAAGCAGCCGGGAAAGGGAAGG	VAPA	ENSG00000101558	-0.17204660271698352	[1151,1281]	[878,845]	-5	dCas9-KRAB	negative selection	5522042
9914466	9914489	18	-	27661255	K562	viability	GCAAGAAAGCAGCCGGGAAAGGG	VAPA	ENSG00000101558	-0.5135239520725086	[1600,1381]	[967,724]	-7	dCas9-KRAB	negative selection	5522043
9914509	9914532	18	-	27661255	K562	viability	GATGAAGCGGGCCGGAGCAAGGG	VAPA	ENSG00000101558	0.39177780913736415	[1270,1494]	[1766,1170]	9	dCas9-KRAB	negative selection	5522044
9944997	9945020	18	-	27260156	BXPC3	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.11758535394251818	[381]	[305,423,587,428]	2	hSpCas9	negative selection	5579596
9944992	9945015	18	+	27260156	BXPC3	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.2615627585615773	[333]	[378,339,428,548]	6	hSpCas9	negative selection	5579597
9931882	9931905	18	+	27260156	BXPC3	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.11782874402890353	[566]	[731,451,695,697]	2	hSpCas9	negative selection	5579598
9931941	9931964	18	+	27260156	BXPC3	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.2282946621823816	[266]	[306,350,390,248]	5	hSpCas9	negative selection	5643843
9937020	9937043	18	-	27260156	BXPC3	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	-0.008619826778675288	[659]	[565,699,754,737]	0	hSpCas9	negative selection	5643844
9936994	9937017	18	+	27260156	BXPC3	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.11156569361444346	[225]	[219,187,227,409]	2	hSpCas9	negative selection	5643845
9944997	9945020	18	-	27260156	A673	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.348844791278773	[381]	[715,618,447,566]	7	hSpCas9	negative selection	5700847
9944992	9945015	18	+	27260156	A673	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.39189588282824017	[333]	[624,527,450,510]	8	hSpCas9	negative selection	5700848
9931882	9931905	18	+	27260156	A673	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.44589893307053713	[566]	[484,368,463,692]	-8	hSpCas9	negative selection	5700849
9931941	9931964	18	+	27260156	A673	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.22248420957836912	[266]	[367,406,288,433]	5	hSpCas9	negative selection	5765094
9937020	9937043	18	-	27260156	A673	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.09998414673909617	[659]	[993,909,666,840]	2	hSpCas9	negative selection	5765095
9936994	9937017	18	+	27260156	A673	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.056570808206858225	[225]	[317,242,324,244]	1	hSpCas9	negative selection	5765096
9944997	9945020	18	-	27260156	A375	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.4177565130179406	[381]	[439,778,682,513]	6	hSpCas9	negative selection	5822098
9944992	9945015	18	+	27260156	A375	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.150921419442965	[333]	[255,735,432,355]	2	hSpCas9	negative selection	5822099
9931882	9931905	18	+	27260156	A375	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.11157907377128781	[566]	[580,792,678,441]	-2	hSpCas9	negative selection	5822100
9931941	9931964	18	+	27260156	A375	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.4819014641489179	[266]	[286,523,526,415]	7	hSpCas9	negative selection	5886345
9937020	9937043	18	-	27260156	A375	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.12261701626660693	[659]	[731,954,906,781]	1	hSpCas9	negative selection	5886346
9936994	9937017	18	+	27260156	A375	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.717941329710497	[225]	[485,450,368,431]	9	hSpCas9	negative selection	5886347
9944997	9945020	18	-	27260156	COLO741	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.13952174944162288	[381]	[606,549,465]	3	hSpCas9	negative selection	5943349
9944992	9945015	18	+	27260156	COLO741	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.4231050718216738	[333]	[561,545,603]	8	hSpCas9	negative selection	5943350
9931882	9931905	18	+	27260156	COLO741	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.034998711300263996	[566]	[1023,643,591]	0	hSpCas9	negative selection	5943351
9931941	9931964	18	+	27260156	COLO741	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.30734245054932385	[266]	[475,497,304]	6	hSpCas9	negative selection	6007596
9937020	9937043	18	-	27260156	COLO741	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.0743728781919013	[659]	[774,858,1008]	1	hSpCas9	negative selection	6007597
9936994	9937017	18	+	27260156	COLO741	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.11551726703517118	[225]	[245,299,380]	2	hSpCas9	negative selection	6007598
9944997	9945020	18	-	27260156	CAL120	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.23095061992760502	[381]	[332,380,918]	3	hSpCas9	negative selection	6064600
9944992	9945015	18	+	27260156	CAL120	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.28813081647360705	[333]	[626,613,302]	4	hSpCas9	negative selection	6064601
9931882	9931905	18	+	27260156	CAL120	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-1.1204084782189747	[566]	[355,397,225]	-9	hSpCas9	negative selection	6064602
9931941	9931964	18	+	27260156	CAL120	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.31959193124579455	[266]	[762,220,313]	5	hSpCas9	negative selection	6128847
9937020	9937043	18	-	27260156	CAL120	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.3347937514714674	[659]	[1243,1174,724]	5	hSpCas9	negative selection	6128848
9936994	9937017	18	+	27260156	CAL120	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.01637836365527945	[225]	[307,333,215]	0	hSpCas9	negative selection	6128849
9944997	9945020	18	-	27260156	CADOES1	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.417381675841405	[381]	[570,403,588,327]	7	hSpCas9	negative selection	6185851
9944992	9945015	18	+	27260156	CADOES1	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.7077712718788581	[333]	[288,497,478,773]	9	hSpCas9	negative selection	6185852
9931882	9931905	18	+	27260156	CADOES1	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.13249961921382591	[566]	[560,599,658,488]	2	hSpCas9	negative selection	6185853
9931941	9931964	18	+	27260156	CADOES1	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.6639515989737996	[266]	[498,346,370,354]	9	hSpCas9	negative selection	6250098
9937020	9937043	18	-	27260156	CADOES1	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.1947358906059118	[659]	[663,764,765,611]	3	hSpCas9	negative selection	6250099
9936994	9937017	18	+	27260156	CADOES1	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.26136838904047854	[225]	[239,234,248,284]	4	hSpCas9	negative selection	6250100
9944997	9945020	18	-	27260156	EWS502	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.04922507324764849	[381]	[359,390,440,494]	0	hSpCas9	negative selection	6307102
9944992	9945015	18	+	27260156	EWS502	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.46996581908386587	[333]	[444,696,460,340]	7	hSpCas9	negative selection	6307103
9931882	9931905	18	+	27260156	EWS502	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.09642655317068582	[566]	[546,393,640,680]	-2	hSpCas9	negative selection	6307104
9931941	9931964	18	+	27260156	EWS502	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.24385071943190306	[266]	[277,381,450,225]	4	hSpCas9	negative selection	6371349
9937020	9937043	18	-	27260156	EWS502	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.1613259676748009	[659]	[579,862,699,1017]	3	hSpCas9	negative selection	6371350
9936994	9937017	18	+	27260156	EWS502	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.24217964879652099	[225]	[343,171,252,364]	4	hSpCas9	negative selection	6371351
9944997	9945020	18	-	27260156	EW8	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.5873789088547058	[381]	[502,418,405,544]	9	hSpCas9	negative selection	6428353
9944992	9945015	18	+	27260156	EW8	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.10338321091149388	[333]	[386,295,237,260]	2	hSpCas9	negative selection	6428354
9931882	9931905	18	+	27260156	EW8	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.006620954746487329	[566]	[583,433,381,471]	0	hSpCas9	negative selection	6428355
9931941	9931964	18	+	27260156	EW8	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.441715572910534	[266]	[564,297,181,178]	7	hSpCas9	negative selection	6492600
9937020	9937043	18	-	27260156	EW8	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.21774198936706202	[659]	[750,497,638,608]	4	hSpCas9	negative selection	6492601
9936994	9937017	18	+	27260156	EW8	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.3568050628810381	[225]	[370,235,149,209]	6	hSpCas9	negative selection	6492602
9944997	9945020	18	-	27260156	CORL105	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.3728529634530772	[381]	[506,453,845,550]	7	hSpCas9	negative selection	6549604
9944992	9945015	18	+	27260156	CORL105	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.5017963313052646	[333]	[554,471,673,533]	8	hSpCas9	negative selection	6549605
9931882	9931905	18	+	27260156	CORL105	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.19670702326545747	[566]	[891,854,783,518]	3	hSpCas9	negative selection	6549606
9931941	9931964	18	+	27260156	CORL105	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.4643277880246932	[266]	[356,385,626,383]	8	hSpCas9	negative selection	6613851
9937020	9937043	18	-	27260156	CORL105	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	-0.0524650707548211	[659]	[711,793,732,736]	-1	hSpCas9	negative selection	6613852
9936994	9937017	18	+	27260156	CORL105	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	-0.1154305156010591	[225]	[281,205,294,203]	-2	hSpCas9	negative selection	6613853
9944997	9945020	18	-	27260156	HS294T	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.37638878165899875	[381]	[176,140,251,200]	5	hSpCas9	negative selection	6670855
9944992	9945015	18	+	27260156	HS294T	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.5262657751179197	[333]	[84,171,303,193]	7	hSpCas9	negative selection	6670856
9931882	9931905	18	+	27260156	HS294T	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.1575403376973236	[566]	[203,207,167,205]	-2	hSpCas9	negative selection	6670857
9931941	9931964	18	+	27260156	HS294T	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.168866990804738	[266]	[113,106,103,143]	2	hSpCas9	negative selection	6735102
9937020	9937043	18	-	27260156	HS294T	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.15072479827164942	[659]	[277,249,266,349]	2	hSpCas9	negative selection	6735103
9936994	9937017	18	+	27260156	HS294T	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.20594825300623787	[225]	[136,61,93,108]	3	hSpCas9	negative selection	6735104
9944997	9945020	18	-	27260156	HCC44	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.13853248603495832	[381]	[474,492,617,338]	2	hSpCas9	negative selection	6792106
9944992	9945015	18	+	27260156	HCC44	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.5695751877867763	[333]	[595,607,428,577]	8	hSpCas9	negative selection	6792107
9931882	9931905	18	+	27260156	HCC44	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.20478758163933897	[566]	[665,412,1395,631]	3	hSpCas9	negative selection	6792108
9931941	9931964	18	+	27260156	HCC44	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.2495102382434351	[266]	[189,479,464,285]	4	hSpCas9	negative selection	6856353
9937020	9937043	18	-	27260156	HCC44	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.406210209727047	[659]	[1145,808,1059,985]	6	hSpCas9	negative selection	6856354
9936994	9937017	18	+	27260156	HCC44	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.37712145186998747	[225]	[295,281,561,231]	6	hSpCas9	negative selection	6856355
9944997	9945020	18	-	27260156	G402	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	-0.1127446094642322	[381]	[597,474,344,335]	-1	hSpCas9	negative selection	6913357
9944992	9945015	18	+	27260156	G402	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.02903221103447895	[333]	[353,740,315,267]	0	hSpCas9	negative selection	6913358
9931882	9931905	18	+	27260156	G402	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.22400310694796216	[566]	[930,347,618,507]	-3	hSpCas9	negative selection	6913359
9931941	9931964	18	+	27260156	G402	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.19085034388666944	[266]	[538,297,362,308]	2	hSpCas9	negative selection	6977604
9937020	9937043	18	-	27260156	G402	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.45111233781612237	[659]	[903,1178,1346,952]	5	hSpCas9	negative selection	6977605
9936994	9937017	18	+	27260156	G402	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.32220428468476614	[225]	[166,174,544,449]	4	hSpCas9	negative selection	6977606
9944997	9945020	18	-	27260156	L33	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.25011254821181966	[381]	[424,197,302,427]	5	hSpCas9	negative selection	7034608
9944992	9945015	18	+	27260156	L33	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.5423014325724962	[333]	[389,128,403,599]	9	hSpCas9	negative selection	7034609
9931882	9931905	18	+	27260156	L33	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.21541625152736008	[566]	[371,265,299,457]	-5	hSpCas9	negative selection	7034610
9931941	9931964	18	+	27260156	L33	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.15813998725633682	[266]	[302,99,252,242]	3	hSpCas9	negative selection	7098855
9937020	9937043	18	-	27260156	L33	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	-0.23156049894153752	[659]	[658,222,322,528]	-5	hSpCas9	negative selection	7098856
9936994	9937017	18	+	27260156	L33	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	-0.10353605817235456	[225]	[238,76,106,242]	-2	hSpCas9	negative selection	7098857
9944997	9945020	18	-	27260156	K562	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.08890072567516769	[381]	[483,386,341,251]	1	hSpCas9	negative selection	7155859
9944992	9945015	18	+	27260156	K562	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.3573392250502611	[333]	[734,282,282,254]	4	hSpCas9	negative selection	7155860
9931882	9931905	18	+	27260156	K562	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.5240891431573482	[566]	[815,638,674,759]	6	hSpCas9	negative selection	7155861
9931941	9931964	18	+	27260156	K562	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.7131575587202199	[266]	[517,148,549,338]	8	hSpCas9	negative selection	7220106
9937020	9937043	18	-	27260156	K562	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.1148613799942757	[659]	[341,898,627,652]	1	hSpCas9	negative selection	7220107
9936994	9937017	18	+	27260156	K562	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.47200256919519235	[225]	[317,181,399,216]	6	hSpCas9	negative selection	7220108
9944997	9945020	18	-	27260156	HT29	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	-0.00886660282977958	[381]	[461,546,360,477]	0	hSpCas9	negative selection	7277110
9944992	9945015	18	+	27260156	HT29	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.2841181802599433	[333]	[497,505,438,527]	5	hSpCas9	negative selection	7277111
9931882	9931905	18	+	27260156	HT29	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.2096904516075515	[566]	[602,688,605,501]	-4	hSpCas9	negative selection	7277112
9931941	9931964	18	+	27260156	HT29	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.2995720741367238	[266]	[343,500,413,346]	6	hSpCas9	negative selection	7341357
9937020	9937043	18	-	27260156	HT29	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.06371511395696805	[659]	[855,745,977,769]	1	hSpCas9	negative selection	7341358
9936994	9937017	18	+	27260156	HT29	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	-0.17128877289171363	[225]	[301,197,251,224]	-3	hSpCas9	negative selection	7341359
9944997	9945020	18	-	27260156	MHHES1	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.4157735780577421	[381]	[605,709,540,467]	7	hSpCas9	negative selection	7398361
9944992	9945015	18	+	27260156	MHHES1	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.03095867902952315	[333]	[397,402,418,325]	0	hSpCas9	negative selection	7398362
9931882	9931905	18	+	27260156	MHHES1	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.24007902863447816	[566]	[560,638,482,490]	-4	hSpCas9	negative selection	7398363
9931941	9931964	18	+	27260156	MHHES1	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.048050775110407895	[266]	[310,428,289,235]	0	hSpCas9	negative selection	7462608
9937020	9937043	18	-	27260156	MHHES1	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.24627325153130541	[659]	[1189,859,721,789]	4	hSpCas9	negative selection	7462609
9936994	9937017	18	+	27260156	MHHES1	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.20172976630249684	[225]	[354,489,213,162]	4	hSpCas9	negative selection	7462610
9944997	9945020	18	-	27260156	MEWO	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.13261561376432834	[381]	[430,368,382]	3	hSpCas9	negative selection	7519612
9944992	9945015	18	+	27260156	MEWO	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.5454960322340224	[333]	[622,341,435]	9	hSpCas9	negative selection	7519613
9931882	9931905	18	+	27260156	MEWO	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.023331703271042004	[566]	[477,568,509]	0	hSpCas9	negative selection	7519614
9931941	9931964	18	+	27260156	MEWO	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.2679480982744761	[266]	[369,233,311]	6	hSpCas9	negative selection	7583859
9937020	9937043	18	-	27260156	MEWO	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	-0.07680316035584456	[659]	[516,581,643]	-2	hSpCas9	negative selection	7583860
9936994	9937017	18	+	27260156	MEWO	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.24753716554775462	[225]	[237,345,165]	5	hSpCas9	negative selection	7583861
9944997	9945020	18	-	27260156	LNCAPCLONEFGC	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.10780037958976552	[381]	[424,323,382,362]	1	hSpCas9	negative selection	7640863
9944992	9945015	18	+	27260156	LNCAPCLONEFGC	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.34327757394624786	[333]	[373,297,545,346]	5	hSpCas9	negative selection	7640864
9931882	9931905	18	+	27260156	LNCAPCLONEFGC	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.29960237290619396	[566]	[305,415,624,354]	-5	hSpCas9	negative selection	7640865
9931941	9931964	18	+	27260156	LNCAPCLONEFGC	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.5945200585743566	[266]	[341,248,447,441]	8	hSpCas9	negative selection	7705110
9937020	9937043	18	-	27260156	LNCAPCLONEFGC	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.5235273690724184	[659]	[771,722,806,1137]	7	hSpCas9	negative selection	7705111
9936994	9937017	18	+	27260156	LNCAPCLONEFGC	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.29087397559727446	[225]	[312,229,197,252]	4	hSpCas9	negative selection	7705112
9944997	9945020	18	-	27260156	PANC0327	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.41687769279093706	[381]	[616,397,638,178]	6	hSpCas9	negative selection	7762114
9944992	9945015	18	+	27260156	PANC0327	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.784890917460135	[333]	[578,367,679,441]	9	hSpCas9	negative selection	7762115
9931882	9931905	18	+	27260156	PANC0327	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.10748101600241933	[566]	[381,668,602,486]	1	hSpCas9	negative selection	7762116
9931941	9931964	18	+	27260156	PANC0327	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.08612012829744031	[266]	[202,306,303,181]	1	hSpCas9	negative selection	7826361
9937020	9937043	18	-	27260156	PANC0327	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.6545540457966074	[659]	[1423,802,902,617]	8	hSpCas9	negative selection	7826362
9936994	9937017	18	+	27260156	PANC0327	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.6882376820263886	[225]	[394,307,436,161]	8	hSpCas9	negative selection	7826363
9944997	9945020	18	-	27260156	NCIH2009	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.1941617458144828	[381]	[617,567,646]	2	hSpCas9	negative selection	7883365
9944992	9945015	18	+	27260156	NCIH2009	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.5901521594811835	[333]	[895,897,346]	7	hSpCas9	negative selection	7883366
9931882	9931905	18	+	27260156	NCIH2009	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.6923729544570091	[566]	[631,373,493]	-7	hSpCas9	negative selection	7883367
9931941	9931964	18	+	27260156	NCIH2009	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.3515709103492524	[266]	[425,434,556]	5	hSpCas9	negative selection	7947612
9937020	9937043	18	-	27260156	NCIH2009	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	-0.28131418444305356	[659]	[712,755,796]	-4	hSpCas9	negative selection	7947613
9936994	9937017	18	+	27260156	NCIH2009	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.13048359751176886	[225]	[461,309,287]	1	hSpCas9	negative selection	7947614
9944997	9945020	18	-	27260156	NCIH1373	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.5966095650387437	[381]	[785,571,702,143]	6	hSpCas9	negative selection	8004616
9944992	9945015	18	+	27260156	NCIH1373	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.41725973934198857	[333]	[442,737,482,74]	4	hSpCas9	negative selection	8004617
9931882	9931905	18	+	27260156	NCIH1373	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.1373810055848097	[566]	[828,731,746,127]	1	hSpCas9	negative selection	8004618
9931941	9931964	18	+	27260156	NCIH1373	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.9951911478964378	[266]	[202,465,1398,59]	8	hSpCas9	negative selection	8068863
9937020	9937043	18	-	27260156	NCIH1373	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.08483595973383284	[659]	[1261,692,639,161]	0	hSpCas9	negative selection	8068864
9936994	9937017	18	+	27260156	NCIH1373	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.6923620211810948	[225]	[502,421,310,108]	7	hSpCas9	negative selection	8068865
9944997	9945020	18	-	27260156	PATU8902	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.8625997231649458	[381]	[659,1551,555,1238]	8	hSpCas9	negative selection	8125867
9944992	9945015	18	+	27260156	PATU8902	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	1.153493399599774	[333]	[1258,1366,734,819]	9	hSpCas9	negative selection	8125868
9931882	9931905	18	+	27260156	PATU8902	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.11904645281091791	[566]	[1023,767,637,459]	-1	hSpCas9	negative selection	8125869
9931941	9931964	18	+	27260156	PATU8902	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.5573152983786225	[266]	[404,489,708,538]	6	hSpCas9	negative selection	8190114
9937020	9937043	18	-	27260156	PATU8902	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.4362573730419035	[659]	[1248,950,1332,1429]	4	hSpCas9	negative selection	8190115
9936994	9937017	18	+	27260156	PATU8902	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	-0.5925919521417655	[225]	[63,373,152,265]	-5	hSpCas9	negative selection	8190116
9944997	9945020	18	-	27260156	PANC1	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.08857282581639375	[381]	[289,595,274,289]	1	hSpCas9	negative selection	8247118
9944992	9945015	18	+	27260156	PANC1	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.36907015601962145	[333]	[340,458,361,337]	6	hSpCas9	negative selection	8247119
9931882	9931905	18	+	27260156	PANC1	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-1.2508356324995267	[566]	[208,333,200,112]	-9	hSpCas9	negative selection	8247120
9931941	9931964	18	+	27260156	PANC1	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.6639253697653247	[266]	[301,466,464,254]	9	hSpCas9	negative selection	8311365
9937020	9937043	18	-	27260156	PANC1	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.16302480960017474	[659]	[531,932,738,423]	2	hSpCas9	negative selection	8311366
9936994	9937017	18	+	27260156	PANC1	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	-0.015455706570981498	[225]	[169,243,110,241]	0	hSpCas9	negative selection	8311367
9944997	9945020	18	-	27260156	PANC0813	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.1782454169193623	[381]	[528,597,543,368]	3	hSpCas9	negative selection	8368369
9944992	9945015	18	+	27260156	PANC0813	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.3899285929608507	[333]	[721,503,473,381]	6	hSpCas9	negative selection	8368370
9931882	9931905	18	+	27260156	PANC0813	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.13432955823435166	[566]	[799,585,581,482]	-2	hSpCas9	negative selection	8368371
9931941	9931964	18	+	27260156	PANC0813	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.3730073110675935	[266]	[484,448,415,287]	6	hSpCas9	negative selection	8432616
9937020	9937043	18	-	27260156	PANC0813	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.07536284949624061	[659]	[859,545,734,1111]	1	hSpCas9	negative selection	8432617
9936994	9937017	18	+	27260156	PANC0813	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.477252472742012	[225]	[592,169,427,310]	7	hSpCas9	negative selection	8432618
9944997	9945020	18	-	27260156	RDES	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.18243698778497086	[381]	[420,408,582,611]	3	hSpCas9	negative selection	8489620
9944992	9945015	18	+	27260156	RDES	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.34231438347270693	[333]	[344,495,440,714]	5	hSpCas9	negative selection	8489621
9931882	9931905	18	+	27260156	RDES	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.008459914236627841	[566]	[431,629,750,881]	0	hSpCas9	negative selection	8489622
9931941	9931964	18	+	27260156	RDES	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.30883319472469717	[266]	[351,427,389,332]	5	hSpCas9	negative selection	8553867
9937020	9937043	18	-	27260156	RDES	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.3508281330316625	[659]	[862,1115,780,1100]	5	hSpCas9	negative selection	8553868
9936994	9937017	18	+	27260156	RDES	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.3683591958469241	[225]	[339,296,296,408]	6	hSpCas9	negative selection	8553869
9944997	9945020	18	-	27260156	PC3	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.03331986039452117	[381]	[245,386,425,544]	0	hSpCas9	negative selection	8610871
9944992	9945015	18	+	27260156	PC3	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.17206361950649146	[333]	[192,322,733,445]	4	hSpCas9	negative selection	8610872
9931882	9931905	18	+	27260156	PC3	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.4237937534652407	[566]	[321,285,721,477]	-7	hSpCas9	negative selection	8610873
9931941	9931964	18	+	27260156	PC3	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.3634407604159934	[266]	[202,270,635,410]	7	hSpCas9	negative selection	8675118
9937020	9937043	18	-	27260156	PC3	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	-0.19420661547267826	[659]	[382,516,993,598]	-4	hSpCas9	negative selection	8675119
9936994	9937017	18	+	27260156	PC3	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	-0.14630522987572392	[225]	[149,223,226,221]	-3	hSpCas9	negative selection	8675120
9944997	9945020	18	-	27260156	PATU8988T	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.3679024102882535	[381]	[283,486,585,553]	6	hSpCas9	negative selection	8732122
9944992	9945015	18	+	27260156	PATU8988T	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.5296023183161221	[333]	[498,292,749,286]	8	hSpCas9	negative selection	8732123
9931882	9931905	18	+	27260156	PATU8988T	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.5171074105629017	[566]	[572,382,272,296]	-7	hSpCas9	negative selection	8732124
9931941	9931964	18	+	27260156	PATU8988T	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.24795743272709725	[266]	[229,424,304,273]	4	hSpCas9	negative selection	8796369
9937020	9937043	18	-	27260156	PATU8988T	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	-0.11185629130103059	[659]	[564,487,729,563]	-2	hSpCas9	negative selection	8796370
9936994	9937017	18	+	27260156	PATU8988T	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.41770214951482953	[225]	[225,275,411,245]	7	hSpCas9	negative selection	8796371
9944997	9945020	18	-	27260156	T47D	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.21940986339215512	[381]	[525,431,470,655]	4	hSpCas9	negative selection	8853373
9944992	9945015	18	+	27260156	T47D	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.4656282046213499	[333]	[648,430,536,541]	8	hSpCas9	negative selection	8853374
9931882	9931905	18	+	27260156	T47D	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.16885881831119232	[566]	[714,658,743,862]	3	hSpCas9	negative selection	8853375
9931941	9931964	18	+	27260156	T47D	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.36802119300389946	[266]	[436,389,380,398]	7	hSpCas9	negative selection	8917620
9937020	9937043	18	-	27260156	T47D	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.03767239818675028	[659]	[833,762,780,780]	0	hSpCas9	negative selection	8917621
9936994	9937017	18	+	27260156	T47D	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	-0.09324552594371927	[225]	[192,201,331,262]	-2	hSpCas9	negative selection	8917622
9944997	9945020	18	-	27260156	SU8686	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.4880892695640412	[381]	[532,513,452,637]	7	hSpCas9	negative selection	8974624
9944992	9945015	18	+	27260156	SU8686	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.35462853920902976	[333]	[385,295,384,685]	6	hSpCas9	negative selection	8974625
9931882	9931905	18	+	27260156	SU8686	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.14145011070519603	[566]	[518,392,809,834]	2	hSpCas9	negative selection	8974626
9931941	9931964	18	+	27260156	SU8686	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.20580134252405802	[266]	[284,239,348,366]	3	hSpCas9	negative selection	9038871
9937020	9937043	18	-	27260156	SU8686	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	-0.3280617153384938	[659]	[465,501,510,627]	-5	hSpCas9	negative selection	9038872
9936994	9937017	18	+	27260156	SU8686	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.22224645104731844	[225]	[378,142,246,278]	4	hSpCas9	negative selection	9038873
9944997	9945020	18	-	27260156	SKES1	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.46227575049972114	[381]	[570,618,494,437]	8	hSpCas9	negative selection	9095875
9944992	9945015	18	+	27260156	SKES1	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.10930462248935469	[333]	[309,435,460,241]	2	hSpCas9	negative selection	9095876
9931882	9931905	18	+	27260156	SKES1	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.016685360974666386	[566]	[446,746,677,384]	0	hSpCas9	negative selection	9095877
9931941	9931964	18	+	27260156	SKES1	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.3520979640452383	[266]	[441,480,228,247]	7	hSpCas9	negative selection	9160122
9937020	9937043	18	-	27260156	SKES1	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.12782352580561185	[659]	[969,720,707,528]	2	hSpCas9	negative selection	9160123
9936994	9937017	18	+	27260156	SKES1	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.01326705041683085	[225]	[233,191,312,170]	0	hSpCas9	negative selection	9160124
9944997	9945020	18	-	27260156	TOV112D	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.49676551621846476	[381]	[692,712,556,258]	8	hSpCas9	negative selection	9217126
9944992	9945015	18	+	27260156	TOV112D	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.43143619478568307	[333]	[419,734,337,379]	7	hSpCas9	negative selection	9217127
9931882	9931905	18	+	27260156	TOV112D	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.03050581614678885	[566]	[859,605,384,413]	0	hSpCas9	negative selection	9217128
9931941	9931964	18	+	27260156	TOV112D	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.2481226723589317	[266]	[234,397,161,482]	5	hSpCas9	negative selection	9281373
9937020	9937043	18	-	27260156	TOV112D	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.05337366891335571	[659]	[776,844,719,453]	1	hSpCas9	negative selection	9281374
9936994	9937017	18	+	27260156	TOV112D	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.22530039769068877	[225]	[445,197,188,224]	4	hSpCas9	negative selection	9281375
9944997	9945020	18	-	27260156	TC71	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.031474155193566944	[381]	[430,446,378,417]	0	hSpCas9	negative selection	9338377
9944992	9945015	18	+	27260156	TC71	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	0.20914070489885206	[333]	[390,354,377,540]	5	hSpCas9	negative selection	9338378
9931882	9931905	18	+	27260156	TC71	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.027554762289407703	[566]	[679,733,462,504]	0	hSpCas9	negative selection	9338379
9931941	9931964	18	+	27260156	TC71	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.21437722301698214	[266]	[286,384,279,381]	5	hSpCas9	negative selection	9402624
9937020	9937043	18	-	27260156	TC71	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	-0.020545621863969632	[659]	[735,689,586,784]	0	hSpCas9	negative selection	9402625
9936994	9937017	18	+	27260156	TC71	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	-0.08948272049419015	[225]	[184,258,172,300]	-2	hSpCas9	negative selection	9402626
9944997	9945020	18	-	27260156	TC32	viability	GTCATCCTTCGTGTGATAACTGG	VAPA	ENSG00000101558	0.2523602744114978	[381]	[474,333,453,455]	4	hSpCas9	negative selection	9459628
9944992	9945015	18	+	27260156	TC32	viability	ACCTGCCAGTTATCACACGAAGG	VAPA	ENSG00000101558	-0.01900628898577572	[333]	[311,189,397,385]	0	hSpCas9	negative selection	9459629
9931882	9931905	18	+	27260156	TC32	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.33570238755281084	[566]	[330,290,598,542]	-6	hSpCas9	negative selection	9459630
9931941	9931964	18	+	27260156	TC32	viability	GGGTCAACTGTGACTGTTTCAGG	VAPA	ENSG00000101558	0.5535939962636968	[266]	[308,380,447,324]	8	hSpCas9	negative selection	9523875
9937020	9937043	18	-	27260156	TC32	viability	TTCAAATACGCATCTCAATTTGG	VAPA	ENSG00000101558	0.3322414905446206	[659]	[585,532,1112,1038]	6	hSpCas9	negative selection	9523876
9936994	9937017	18	+	27260156	TC32	viability	GGCAAAACCTGATGAATTAATGG	VAPA	ENSG00000101558	0.2730015934082036	[225]	[270,219,231,296]	5	hSpCas9	negative selection	9523877
9945025	9945048	18	+	27869803	HPAFII	viability after 27 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.8359091542731873	[315]	[253,331,NaN]	6	hSpCas9	negative selection	9565241
9945025	9945048	18	+	27869803	HPAFII	viability after 15 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.3948583776971952	[315]	[411,467,NaN]	4	hSpCas9	negative selection	9647690
9945025	9945048	18	+	27869803	ASPC1	viability after 36 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.7176765287746236	[661]	[705,416,117]	7	hSpCas9	negative selection	9730139
9945025	9945048	18	+	27869803	PATU8988S	viability after 35 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.4834702616006089	[692]	[485,293,NaN]	5	hSpCas9	negative selection	9812588
9945025	9945048	18	+	27869803	PATU8988S	viability after 31 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.7007425267120113	[692]	[493,391,NaN]	7	hSpCas9	negative selection	9895037
9945025	9945048	18	+	27869803	HPAFII	viability after 35 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	0.9671419709877911	[315]	[268,361,NaN]	6	hSpCas9	negative selection	9977486
9945025	9945048	18	+	27869803	HPAFII	viability after 31 days	GGGACTCAGTGTGTTGAAACAGG	VAPA	ENSG00000101558	1.234161098620505	[315]	[320,521,NaN]	8	hSpCas9	negative selection	10059935
9914276	9914299	18	-	28162770	P31FUJ	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.39527690137148397	[168]	[150]	-4	hSpCas9	negative selection	10262938
9954117	9954140	18	-	28162770	P31FUJ	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	-0.34482882214849	[347]	[321]	-3	hSpCas9	negative selection	10262939
9931896	9931919	18	-	28162770	P31FUJ	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-1.4350449261294194	[236]	[102]	-7	hSpCas9	negative selection	10262940
9936192	9936215	18	+	28162770	P31FUJ	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	-1.2667495363377164	[42]	[20]	-7	hSpCas9	negative selection	10262941
9931882	9931905	18	+	28162770	P31FUJ	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.799149026968188	[153]	[103]	-6	hSpCas9	negative selection	10262942
9914254	9914277	18	-	28162770	P31FUJ	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	0.2205053117921824	[278]	[381]	2	hSpCas9	negative selection	10262943
9914264	9914287	18	-	28162770	P31FUJ	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	-0.868329586126903	[420]	[270]	-6	hSpCas9	negative selection	10262944
9950449	9950472	18	-	28162770	P31FUJ	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.005045208008836566	[702]	[828]	0	hSpCas9	negative selection	10262945
9914298	9914321	18	-	28162770	P31FUJ	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-0.4041204411565573	[258]	[229]	-4	hSpCas9	negative selection	10262946
9954140	9954163	18	-	28162770	P31FUJ	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	-0.05910403987000962	[296]	[334]	0	hSpCas9	negative selection	10262947
9914276	9914299	18	-	28162770	TF1	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10432304
9954117	9954140	18	-	28162770	TF1	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10432305
9931896	9931919	18	-	28162770	TF1	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10432306
9936192	9936215	18	+	28162770	TF1	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10432307
9931882	9931905	18	+	28162770	TF1	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	NaN	[NaN]	[72]	1	hSpCas9	negative selection	10432308
9914254	9914277	18	-	28162770	TF1	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	NaN	[NaN]	[296]	1	hSpCas9	negative selection	10432309
9914264	9914287	18	-	28162770	TF1	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	NaN	[NaN]	[235]	1	hSpCas9	negative selection	10432310
9950449	9950472	18	-	28162770	TF1	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	NaN	[NaN]	[723]	1	hSpCas9	negative selection	10432311
9914298	9914321	18	-	28162770	TF1	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10432312
9954140	9954163	18	-	28162770	TF1	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	NaN	[NaN]	[386]	1	hSpCas9	negative selection	10432313
9914276	9914299	18	-	28162770	SKM1	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-1.0735404650179698	[74]	[62]	-7	hSpCas9	negative selection	10601670
9954117	9954140	18	-	28162770	SKM1	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	-0.24298846363203558	[80]	[120]	-2	hSpCas9	negative selection	10601671
9931896	9931919	18	-	28162770	SKM1	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-1.7334650234203481	[78]	[41]	-8	hSpCas9	negative selection	10601672
9936192	9936215	18	+	28162770	SKM1	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	0.8884916847830095	[10]	[35]	8	hSpCas9	negative selection	10601673
9931882	9931905	18	+	28162770	SKM1	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-1.6919411574576326	[52]	[28]	-8	hSpCas9	negative selection	10601674
9914254	9914277	18	-	28162770	SKM1	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	0.48118983428377093	[61]	[152]	5	hSpCas9	negative selection	10601675
9914264	9914287	18	-	28162770	SKM1	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	0.08488889758651297	[103]	[194]	0	hSpCas9	negative selection	10601676
9950449	9950472	18	-	28162770	SKM1	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.2572872117826337	[176]	[373]	2	hSpCas9	negative selection	10601677
9914298	9914321	18	-	28162770	SKM1	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-0.26946067499322696	[44]	[65]	-2	hSpCas9	negative selection	10601678
9954140	9954163	18	-	28162770	SKM1	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	-0.07877711338411697	[45]	[76]	0	hSpCas9	negative selection	10601679
9914276	9914299	18	-	28162770	SKM1	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-1.0735404650179698	[74]	[62]	-7	hSpCas9	negative selection	10771036
9954117	9954140	18	-	28162770	SKM1	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	-0.24298846363203558	[80]	[120]	-2	hSpCas9	negative selection	10771037
9931896	9931919	18	-	28162770	SKM1	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-1.7334650234203481	[78]	[41]	-8	hSpCas9	negative selection	10771038
9936192	9936215	18	+	28162770	SKM1	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	0.8884916847830095	[10]	[35]	8	hSpCas9	negative selection	10771039
9931882	9931905	18	+	28162770	SKM1	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-1.6919411574576326	[52]	[28]	-8	hSpCas9	negative selection	10771040
9914254	9914277	18	-	28162770	SKM1	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	0.48118983428377093	[61]	[152]	5	hSpCas9	negative selection	10771041
9914264	9914287	18	-	28162770	SKM1	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	0.08488889758651297	[103]	[194]	0	hSpCas9	negative selection	10771042
9950449	9950472	18	-	28162770	SKM1	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.2572872117826337	[176]	[373]	2	hSpCas9	negative selection	10771043
9914298	9914321	18	-	28162770	SKM1	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-0.26946067499322696	[44]	[65]	-2	hSpCas9	negative selection	10771044
9954140	9954163	18	-	28162770	SKM1	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	-0.07877711338411697	[45]	[76]	0	hSpCas9	negative selection	10771045
9914276	9914299	18	-	28162770	PL21	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.821555456609999	[267]	[65]	-5	hSpCas9	negative selection	10940402
9954117	9954140	18	-	28162770	PL21	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	0.7977685270466368	[188]	[142]	6	hSpCas9	negative selection	10940403
9931896	9931919	18	-	28162770	PL21	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-2.2743463498702665	[288]	[25]	-8	hSpCas9	negative selection	10940404
9936192	9936215	18	+	28162770	PL21	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	-2.7998603855106805	[47]	[2]	-9	hSpCas9	negative selection	10940405
9931882	9931905	18	+	28162770	PL21	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-2.8148107269766514	[193]	[11]	-9	hSpCas9	negative selection	10940406
9914254	9914277	18	-	28162770	PL21	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	1.0695555046791758	[207]	[189]	8	hSpCas9	negative selection	10940407
9914264	9914287	18	-	28162770	PL21	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	0.3291260552093982	[277]	[151]	3	hSpCas9	negative selection	10940408
9950449	9950472	18	-	28162770	PL21	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.2366654905144343	[506]	[259]	2	hSpCas9	negative selection	10940409
9914298	9914321	18	-	28162770	PL21	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-0.3315808649548565	[132]	[45]	-2	hSpCas9	negative selection	10940410
9954140	9954163	18	-	28162770	PL21	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	-0.9283349434594893	[222]	[50]	-6	hSpCas9	negative selection	10940411
9914276	9914299	18	-	28162770	P31FUJ	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.39527690137148397	[168]	[150]	-4	hSpCas9	negative selection	11109768
9954117	9954140	18	-	28162770	P31FUJ	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	-0.34482882214849	[347]	[321]	-3	hSpCas9	negative selection	11109769
9931896	9931919	18	-	28162770	P31FUJ	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-1.4350449261294194	[236]	[102]	-7	hSpCas9	negative selection	11109770
9936192	9936215	18	+	28162770	P31FUJ	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	-1.2667495363377164	[42]	[20]	-7	hSpCas9	negative selection	11109771
9931882	9931905	18	+	28162770	P31FUJ	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.799149026968188	[153]	[103]	-6	hSpCas9	negative selection	11109772
9914254	9914277	18	-	28162770	P31FUJ	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	0.2205053117921824	[278]	[381]	2	hSpCas9	negative selection	11109773
9914264	9914287	18	-	28162770	P31FUJ	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	-0.868329586126903	[420]	[270]	-6	hSpCas9	negative selection	11109774
9950449	9950472	18	-	28162770	P31FUJ	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.005045208008836566	[702]	[828]	0	hSpCas9	negative selection	11109775
9914298	9914321	18	-	28162770	P31FUJ	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-0.4041204411565573	[258]	[229]	-4	hSpCas9	negative selection	11109776
9954140	9954163	18	-	28162770	P31FUJ	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	-0.05910403987000962	[296]	[334]	0	hSpCas9	negative selection	11109777
9914276	9914299	18	-	28162770	OCIAML5	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.3229573048763583	[157]	[227]	-2	hSpCas9	negative selection	11279134
9954117	9954140	18	-	28162770	OCIAML5	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	0.41692939320851385	[160]	[387]	3	hSpCas9	negative selection	11279135
9931896	9931919	18	-	28162770	OCIAML5	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-0.8183834446077082	[126]	[129]	-5	hSpCas9	negative selection	11279136
9936192	9936215	18	+	28162770	OCIAML5	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	0.14793342913600305	[41]	[83]	1	hSpCas9	negative selection	11279137
9931882	9931905	18	+	28162770	OCIAML5	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.6700687371211095	[118]	[134]	-4	hSpCas9	negative selection	11279138
9914254	9914277	18	-	28162770	OCIAML5	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	1.528755213076934	[95]	[499]	9	hSpCas9	negative selection	11279139
9914264	9914287	18	-	28162770	OCIAML5	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	-0.6132797112768804	[249]	[294]	-4	hSpCas9	negative selection	11279140
9950449	9950472	18	-	28162770	OCIAML5	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.6415341877519447	[439]	[1238]	5	hSpCas9	negative selection	11279141
9914298	9914321	18	-	28162770	OCIAML5	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	0.02928893263738397	[94]	[174]	0	hSpCas9	negative selection	11279142
9954140	9954163	18	-	28162770	OCIAML5	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	0.46986152402336523	[183]	[459]	4	hSpCas9	negative selection	11279143
9914276	9914299	18	-	28162770	EOL1	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.13188817405918046	[390]	[187]	-1	hSpCas9	negative selection	11448500
9954117	9954140	18	-	28162770	EOL1	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	0.3164680312247248	[345]	[226]	3	hSpCas9	negative selection	11448501
9931896	9931919	18	-	28162770	EOL1	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-2.264873405497575	[446]	[48]	-8	hSpCas9	negative selection	11448502
9936192	9936215	18	+	28162770	EOL1	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	-1.8724652062656106	[138]	[19]	-8	hSpCas9	negative selection	11448503
9931882	9931905	18	+	28162770	EOL1	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-1.4942418625694167	[384]	[71]	-7	hSpCas9	negative selection	11448504
9914254	9914277	18	-	28162770	EOL1	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	-0.37801499844989667	[406]	[164]	-3	hSpCas9	negative selection	11448505
9914264	9914287	18	-	28162770	EOL1	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	-0.8659988628005157	[383]	[110]	-6	hSpCas9	negative selection	11448506
9950449	9950472	18	-	28162770	EOL1	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.10581545952077942	[731]	[414]	1	hSpCas9	negative selection	11448507
9914298	9914321	18	-	28162770	EOL1	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-1.952441338324122	[190]	[25]	-8	hSpCas9	negative selection	11448508
9954140	9954163	18	-	28162770	EOL1	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	0.06205129532046966	[239]	[131]	0	hSpCas9	negative selection	11448509
9914276	9914299	18	-	28162770	MOLM13	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.4142053022167993	[410]	[222]	-2	hSpCas9	negative selection	11617866
9954117	9954140	18	-	28162770	MOLM13	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	0.4857668722748347	[400]	[405]	3	hSpCas9	negative selection	11617867
9931896	9931919	18	-	28162770	MOLM13	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-1.0486861441963273	[308]	[107]	-5	hSpCas9	negative selection	11617868
9936192	9936215	18	+	28162770	MOLM13	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	-0.06816351869563109	[57]	[39]	0	hSpCas9	negative selection	11617869
9931882	9931905	18	+	28162770	MOLM13	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.8834396297833427	[346]	[135]	-5	hSpCas9	negative selection	11617870
9914254	9914277	18	-	28162770	MOLM13	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	0.626393203907066	[309]	[345]	5	hSpCas9	negative selection	11617871
9914264	9914287	18	-	28162770	MOLM13	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	0.45233456734973704	[372]	[368]	3	hSpCas9	negative selection	11617872
9950449	9950472	18	-	28162770	MOLM13	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.7986039423410354	[752]	[946]	6	hSpCas9	negative selection	11617873
9914298	9914321	18	-	28162770	MOLM13	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	0.7027944141945754	[163]	[192]	5	hSpCas9	negative selection	11617874
9954140	9954163	18	-	28162770	MOLM13	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	0.4291198113800036	[263]	[256]	3	hSpCas9	negative selection	11617875
9914276	9914299	18	-	28162770	HEL	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-1.731656682781141	[279]	[53]	-7	hSpCas9	negative selection	11787232
9954117	9954140	18	-	28162770	HEL	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	-0.7537785793076889	[386]	[146]	-5	hSpCas9	negative selection	11787233
9931896	9931919	18	-	28162770	HEL	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-1.5205834346177085	[326]	[72]	-7	hSpCas9	negative selection	11787234
9936192	9936215	18	+	28162770	HEL	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	-2.835308464804288	[77]	[6]	-8	hSpCas9	negative selection	11787235
9931882	9931905	18	+	28162770	HEL	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-2.4359181118746416	[244]	[28]	-8	hSpCas9	negative selection	11787236
9914254	9914277	18	-	28162770	HEL	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	0.798256409621644	[245]	[273]	7	hSpCas9	negative selection	11787237
9914264	9914287	18	-	28162770	HEL	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	-0.97423406362342	[318]	[103]	-6	hSpCas9	negative selection	11787238
9950449	9950472	18	-	28162770	HEL	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.4106362857184538	[645]	[549]	3	hSpCas9	negative selection	11787239
9914298	9914321	18	-	28162770	HEL	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-1.2141362259010458	[162]	[44]	-6	hSpCas9	negative selection	11787240
9954140	9954163	18	-	28162770	HEL	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	-0.5378334136414641	[237]	[104]	-4	hSpCas9	negative selection	11787241
9914276	9914299	18	-	28162770	MV411	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-0.10740516657732196	[265]	[207]	-1	hSpCas9	negative selection	11956598
9954117	9954140	18	-	28162770	MV411	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	-0.39430214164363775	[297]	[190]	-3	hSpCas9	negative selection	11956599
9931896	9931919	18	-	28162770	MV411	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-0.4832417805359996	[228]	[137]	-4	hSpCas9	negative selection	11956600
9936192	9936215	18	+	28162770	MV411	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	-0.007819504459299242	[36]	[30]	0	hSpCas9	negative selection	11956601
9931882	9931905	18	+	28162770	MV411	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	0.36389652737015826	[225]	[244]	3	hSpCas9	negative selection	11956602
9914254	9914277	18	-	28162770	MV411	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	0.8712193003944597	[219]	[338]	7	hSpCas9	negative selection	11956603
9914264	9914287	18	-	28162770	MV411	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	0.6378377705672449	[250]	[328]	6	hSpCas9	negative selection	11956604
9950449	9950472	18	-	28162770	MV411	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.6049240274994605	[536]	[687]	5	hSpCas9	negative selection	11956605
9914298	9914321	18	-	28162770	MV411	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	2.1535459858728734	[122]	[460]	9	hSpCas9	negative selection	11956606
9954140	9954163	18	-	28162770	MV411	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	0.45179604928896155	[183]	[211]	4	hSpCas9	negative selection	11956607
9914276	9914299	18	-	28162770	MONOMAC1	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-1.2508081035005343	[163]	[78]	-7	hSpCas9	negative selection	12125964
9954117	9954140	18	-	28162770	MONOMAC1	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	-0.35498920683579016	[134]	[120]	-3	hSpCas9	negative selection	12125965
9931896	9931919	18	-	28162770	MONOMAC1	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-2.739935288214166	[168]	[28]	-9	hSpCas9	negative selection	12125966
9936192	9936215	18	+	28162770	MONOMAC1	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	-1.8100137239503065	[51]	[16]	-8	hSpCas9	negative selection	12125967
9931882	9931905	18	+	28162770	MONOMAC1	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-0.3303033779230179	[101]	[92]	-3	hSpCas9	negative selection	12125968
9914254	9914277	18	-	28162770	MONOMAC1	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	-0.36601301910831713	[189]	[168]	-3	hSpCas9	negative selection	12125969
9914264	9914287	18	-	28162770	MONOMAC1	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	0.4888545625123834	[160]	[258]	5	hSpCas9	negative selection	12125970
9950449	9950472	18	-	28162770	MONOMAC1	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.7540535524595002	[344]	[666]	7	hSpCas9	negative selection	12125971
9914298	9914321	18	-	28162770	MONOMAC1	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-1.4351965842543182	[91]	[38]	-8	hSpCas9	negative selection	12125972
9954140	9954163	18	-	28162770	MONOMAC1	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	-0.19703684705955352	[123]	[123]	-2	hSpCas9	negative selection	12125973
9914276	9914299	18	-	28162770	OCIAML2	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-2.44415761388097	[53]	[54]	-8	hSpCas9	negative selection	12295330
9954117	9954140	18	-	28162770	OCIAML2	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	-1.223989857659036	[58]	[139]	-7	hSpCas9	negative selection	12295331
9931896	9931919	18	-	28162770	OCIAML2	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-2.523097245136297	[55]	[53]	-8	hSpCas9	negative selection	12295332
9936192	9936215	18	+	28162770	OCIAML2	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	-1.0783124024634008	[7]	[20]	-6	hSpCas9	negative selection	12295333
9931882	9931905	18	+	28162770	OCIAML2	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-1.9512556661485818	[29]	[42]	-8	hSpCas9	negative selection	12295334
9914254	9914277	18	-	28162770	OCIAML2	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	-0.09559039389523633	[47]	[248]	-1	hSpCas9	negative selection	12295335
9914264	9914287	18	-	28162770	OCIAML2	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	-0.7087895624369259	[68]	[233]	-5	hSpCas9	negative selection	12295336
9950449	9950472	18	-	28162770	OCIAML2	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.5004930974677024	[81]	[642]	5	hSpCas9	negative selection	12295337
9914298	9914321	18	-	28162770	OCIAML2	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-0.2227023117985757	[23]	[113]	-2	hSpCas9	negative selection	12295338
9954140	9954163	18	-	28162770	OCIAML2	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	-0.4288096495475342	[33]	[139]	-3	hSpCas9	negative selection	12295339
9914276	9914299	18	-	28162770	OCIAML3	viability	GATCTGCTCGTGCTTCGCCATGG	VAPA	ENSG00000101558	-1.7717947595394459	[68]	[60]	-8	hSpCas9	negative selection	12464696
9954117	9954140	18	-	28162770	OCIAML3	viability	ACTGGTGACATTATCTCTGAAGG	VAPA	ENSG00000101558	-0.7289372204102716	[83]	[152]	-5	hSpCas9	negative selection	12464697
9931896	9931919	18	-	28162770	OCIAML3	viability	GGCCTCACACAGTACCGGCGAGG	VAPA	ENSG00000101558	-2.0289446970407115	[72]	[53]	-8	hSpCas9	negative selection	12464698
9936192	9936215	18	+	28162770	OCIAML3	viability	CACTTCAGATATGGAAGCTGTGG	VAPA	ENSG00000101558	0.017427071758184143	[17]	[54]	0	hSpCas9	negative selection	12464699
9931882	9931905	18	+	28162770	OCIAML3	viability	TGAAGACTACAGCACCTCGCCGG	VAPA	ENSG00000101558	-1.5308138138369691	[66]	[69]	-8	hSpCas9	negative selection	12464700
9914254	9914277	18	-	28162770	OCIAML3	viability	GCCCCTGAGGCGGACGCCATCGG	VAPA	ENSG00000101558	0.346435514995382	[67]	[260]	3	hSpCas9	negative selection	12464701
9914264	9914287	18	-	28162770	OCIAML3	viability	CTTCGCCATGGCCCCTGAGGCGG	VAPA	ENSG00000101558	-0.1394417768586821	[80]	[221]	-1	hSpCas9	negative selection	12464702
9950449	9950472	18	-	28162770	OCIAML3	viability	ACACTGTGTGGTTTTGGCATAGG	VAPA	ENSG00000101558	0.26286741757723986	[179]	[651]	2	hSpCas9	negative selection	12464703
9914298	9914321	18	-	28162770	OCIAML3	viability	CTGTGGGCGGATCGAGGACCAGG	VAPA	ENSG00000101558	-0.39845683120635633	[30]	[70]	-3	hSpCas9	negative selection	12464704
9954140	9954163	18	-	28162770	OCIAML3	viability	ACAACAAGAAGTGAAGGAAGAGG	VAPA	ENSG00000101558	0.6836964543065157	[52]	[256]	6	hSpCas9	negative selection	12464705