Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 223082
• Symbol: ZNRF2
• Description: zinc and ring finger 2

DataSource: http://genomecrispr.dkfz.de/#!/results/ZNRF2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
30285355	30285378	7	+	26472758	Jiyoye	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	0.9054262490336988	[79]	[112]	6	hSpCas9	negative selection	190610
30355766	30355789	7	+	26472758	Jiyoye	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	-0.1314934669413478	[137]	[94]	-1	hSpCas9	negative selection	190611
30285424	30285447	7	+	26472758	Jiyoye	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	0.20740586913009612	[115]	[100]	1	hSpCas9	negative selection	190612
30355730	30355753	7	+	26472758	Jiyoye	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.10403076229792685	[495]	[401]	0	hSpCas9	negative selection	190613
30285709	30285732	7	+	26472758	Jiyoye	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	1.4014842694280178	[126]	[252]	8	hSpCas9	negative selection	190614
30285434	30285457	7	+	26472758	Jiyoye	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	1.389897390074038	[83]	[165]	8	hSpCas9	negative selection	190615
30285796	30285819	7	-	26472758	Jiyoye	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	5.96176423318351	[0]	[46]	9	hSpCas9	negative selection	190616
30285811	30285834	7	-	26472758	Jiyoye	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	-0.7695069861117478	[320]	[141]	-5	hSpCas9	negative selection	190617
30285505	30285528	7	-	26472758	Jiyoye	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	0.6817977616148789	[61]	[74]	5	hSpCas9	negative selection	190618
30285355	30285378	7	+	26472758	KBM7	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	0.15910597059280873	[530,420]	[329,174]	1	hSpCas9	negative selection	381728
30355766	30355789	7	+	26472758	KBM7	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	0.4546384293165381	[456,432]	[412,174]	5	hSpCas9	negative selection	381729
30285424	30285447	7	+	26472758	KBM7	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	0.2302568320577777	[546,359]	[206,280]	2	hSpCas9	negative selection	381730
30355730	30355753	7	+	26472758	KBM7	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.6370392194666881	[1462,1349]	[1449,652]	7	hSpCas9	negative selection	381731
30285709	30285732	7	+	26472758	KBM7	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	-0.3988683570061762	[848,678]	[238,298]	-4	hSpCas9	negative selection	381732
30285434	30285457	7	+	26472758	KBM7	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.44661654694570246	[590,551]	[390,344]	5	hSpCas9	negative selection	381733
30285796	30285819	7	-	26472758	KBM7	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	0.09673330202010577	[258,316]	[146,146]	0	hSpCas9	negative selection	381734
30285811	30285834	7	-	26472758	KBM7	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	0.435298684702216	[1205,1155]	[688,809]	5	hSpCas9	negative selection	381735
30285505	30285528	7	-	26472758	KBM7	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	0.1485872723564182	[424,371]	[163,245]	1	hSpCas9	negative selection	381736
30285355	30285378	7	+	26472758	Raji	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	-0.4391048175329209	[221]	[37]	-4	hSpCas9	negative selection	572846
30355766	30355789	7	+	26472758	Raji	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	0.33267584721584215	[283]	[82]	3	hSpCas9	negative selection	572847
30285424	30285447	7	+	26472758	Raji	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	0.20523085877174413	[227]	[60]	2	hSpCas9	negative selection	572848
30355730	30355753	7	+	26472758	Raji	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.17104217259591725	[531]	[138]	1	hSpCas9	negative selection	572849
30285709	30285732	7	+	26472758	Raji	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	0.06298941601514596	[395]	[95]	0	hSpCas9	negative selection	572850
30285434	30285457	7	+	26472758	Raji	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.17361723377368632	[297]	[77]	1	hSpCas9	negative selection	572851
30285796	30285819	7	-	26472758	Raji	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	0.42201913769460586	[118]	[36]	4	hSpCas9	negative selection	572852
30285811	30285834	7	-	26472758	Raji	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	-0.4212165227284441	[501]	[86]	-3	hSpCas9	negative selection	572853
30285505	30285528	7	-	26472758	Raji	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	-0.01814734671025936	[191]	[43]	0	hSpCas9	negative selection	572854
30285355	30285378	7	+	26472758	K562	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	0.6754419311179899	[358]	[483]	5	hSpCas9	negative selection	763964
30355766	30355789	7	+	26472758	K562	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	1.0348503466875825	[391]	[677]	8	hSpCas9	negative selection	763965
30285424	30285447	7	+	26472758	K562	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	-0.21396884675144284	[517]	[376]	-1	hSpCas9	negative selection	763966
30355730	30355753	7	+	26472758	K562	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.22554325072907644	[1153]	[1138]	1	hSpCas9	negative selection	763967
30285709	30285732	7	+	26472758	K562	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	-0.7578128196321359	[646]	[322]	-4	hSpCas9	negative selection	763968
30285434	30285457	7	+	26472758	K562	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	1.2478013670610992	[425]	[853]	9	hSpCas9	negative selection	763969
30285796	30285819	7	-	26472758	K562	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	-0.45096776274836003	[284]	[175]	-3	hSpCas9	negative selection	763970
30285811	30285834	7	-	26472758	K562	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	-0.2470741002031489	[1000]	[711]	-2	hSpCas9	negative selection	763971
30285505	30285528	7	-	26472758	K562	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	0.6532242732337763	[231]	[307]	5	hSpCas9	negative selection	763972
30285422	30285445	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATCTACCTTCCAGTAGCAGCGG	ZNRF2	ENSG00000180233	0.2754949962547693	[2,3]	[3,2]	6	hSpCas9	positive selection	3035636
30285592	30285615	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCAGCCGCTCCCTCGGCGGGG	ZNRF2	ENSG00000180233	-0.4521735721226906	[2,2]	[2,0]	-6	hSpCas9	positive selection	3035637
30285427	30285450	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCCTCCGCTGCTACTGGAAGG	ZNRF2	ENSG00000180233	-0.13036486332904934	[3,3]	[3,0]	-2	hSpCas9	positive selection	3035638
30285435	30285458	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.15568328444065632	[4,4]	[4,3]	3	hSpCas9	positive selection	3035639
30285422	30285445	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATCTACCTTCCAGTAGCAGCGG	ZNRF2	ENSG00000180233	0.48387215619628465	[2,2]	[2,2]	8	hSpCas9	positive selection	3103494
30285592	30285615	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCAGCCGCTCCCTCGGCGGGG	ZNRF2	ENSG00000180233	-0.4884505904842238	[2,2]	[0,0]	-7	hSpCas9	positive selection	3103495
30285427	30285450	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCCTCCGCTGCTACTGGAAGG	ZNRF2	ENSG00000180233	-0.07337278344777365	[3,3]	[2,1]	-1	hSpCas9	positive selection	3103496
30285435	30285458	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.3437992644579458	[4,4]	[4,3]	6	hSpCas9	positive selection	3103497
30323716	30323739		+	24336571	A375	resistance to PLX after 7 days	AAGCCACGAATAACCTATAATGG	ZNRF2	ENSG00000180233	-0.400924352125799	[5,5]	[3,3]	-9	hSpCas9	positive selection	3158393
30355765	30355788		+	24336571	A375	resistance to PLX after 7 days	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.3213559932121466	[11,10]	[8,7]	-8	hSpCas9	positive selection	3158394
30355730	30355753		+	24336571	A375	resistance to PLX after 7 days	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.5723840812464523	[3,4]	[6,5]	9	hSpCas9	positive selection	3158395
30323719	30323742		-	24336571	A375	resistance to PLX after 7 days	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.09798663982534017	[11,11]	[11,12]	3	hSpCas9	positive selection	3158397
30323716	30323739		+	24336571	A375	resistance to PLX after 14 days	AAGCCACGAATAACCTATAATGG	ZNRF2	ENSG00000180233	-0.5447190626405224	[7,6]	[1,1]	-6	hSpCas9	positive selection	3216186
30355765	30355788		+	24336571	A375	resistance to PLX after 14 days	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.9409517184344305	[7,14]	[2,1]	-9	hSpCas9	positive selection	3216187
30355730	30355753		+	24336571	A375	resistance to PLX after 14 days	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.2788551547390121	[5,3]	[1,1]	3	hSpCas9	positive selection	3216188
30323719	30323742		-	24336571	A375	resistance to PLX after 14 days	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	1.9216111238976004	[10,10]	[19,20]	9	hSpCas9	positive selection	3216190
30323716	30323739		+	24336571	A375	viability after 7 days	AAGCCACGAATAACCTATAATGG	ZNRF2	ENSG00000180233	-0.4909791233581412	[8]	[5,5]	-6	hSpCas9	negative selection	3273979
30355765	30355788		+	24336571	A375	viability after 7 days	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.4863483005613105	[7]	[11,10]	7	hSpCas9	negative selection	3273980
30355730	30355753		+	24336571	A375	viability after 7 days	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	-0.8149582841544889	[8]	[3,4]	-8	hSpCas9	negative selection	3273981
30323719	30323742		-	24336571	A375	viability after 7 days	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	-0.2694875102153158	[14]	[11,11]	-4	hSpCas9	negative selection	3273983
30323716	30323739		+	24336571	A375	viability after 14 days	AAGCCACGAATAACCTATAATGG	ZNRF2	ENSG00000180233	-0.12824618727348103	[8]	[7,6]	-1	hSpCas9	negative selection	3331772
30355765	30355788		+	24336571	A375	viability after 14 days	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.5670266735400522	[7]	[7,14]	7	hSpCas9	negative selection	3331773
30355730	30355753		+	24336571	A375	viability after 14 days	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	-0.7589496806814879	[8]	[5,3]	-7	hSpCas9	negative selection	3331774
30323719	30323742		-	24336571	A375	viability after 14 days	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	-0.3211209408165581	[14]	[10,10]	-4	hSpCas9	negative selection	3331776
30355765	30355788	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.36250844813789157	[118,118]	[0,0]	2	hSpCas9	positive selection	3403762
30355768	30355791	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	2.257326211445835	[31,31]	[0,0]	8	hSpCas9	positive selection	3403763
30285421	30285444	7	+	26780180	HT29	viability (Avana library 4 designs)	GATCTACCTTCCAGTAGCAGCGG	ZNRF2	ENSG00000180233	1.17720520750036	[]	[]	4	hSpCas9	negative selection	3474994
30285591	30285614	7	+	26780180	HT29	viability (Avana library 4 designs)	GCGCAGCCGCTCCCTCGGCGGGG	ZNRF2	ENSG00000180233	1.20638038826361	[]	[]	5	hSpCas9	negative selection	3474995
30285427	30285450	7	-	26780180	HT29	viability (Avana library 4 designs)	GCGCCTCCGCTGCTACTGGAAGG	ZNRF2	ENSG00000180233	0.0940037637985085	[]	[]	0	hSpCas9	negative selection	3474996
30285434	30285457	7	+	26780180	HT29	viability (Avana library 4 designs)	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	-0.463617859118044	[]	[]	-7	hSpCas9	negative selection	3474997
30285434	30285457	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	6.35179151246227	[]	[]	9	hSpCas9	negative selection	3583555
30285421	30285444	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATCTACCTTCCAGTAGCAGCGG	ZNRF2	ENSG00000180233	-3.37202263038571	[]	[]	-4	hSpCas9	negative selection	3583556
30285591	30285614	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCAGCCGCTCCCTCGGCGGGG	ZNRF2	ENSG00000180233	5.19533635774094	[]	[]	8	hSpCas9	negative selection	3583557
30285427	30285450	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCCTCCGCTGCTACTGGAAGG	ZNRF2	ENSG00000180233	-0.247018220559585	[]	[]	0	hSpCas9	negative selection	3583558
30285383	30285406	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCGTGCGGCCGTTAGCGGCGG	ZNRF2	ENSG00000180233	3.89389973636499	[]	[]	6	hSpCas9	negative selection	3583559
30285355	30285378	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	3.3524754516509	[]	[]	5	hSpCas9	negative selection	3583560
30285434	30285457	7	+	26780180	A375	viability (Avana lentiGuide)	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	-0.16869418929099	[]	[]	0	hSpCas9	negative selection	3692214
30285421	30285444	7	+	26780180	A375	viability (Avana lentiGuide)	GATCTACCTTCCAGTAGCAGCGG	ZNRF2	ENSG00000180233	19.9053717230463	[]	[]	8	hSpCas9	negative selection	3692215
30285591	30285614	7	+	26780180	A375	viability (Avana lentiGuide)	GCGCAGCCGCTCCCTCGGCGGGG	ZNRF2	ENSG00000180233	5.35236260790324	[]	[]	5	hSpCas9	negative selection	3692216
30285427	30285450	7	-	26780180	A375	viability (Avana lentiGuide)	GCGCCTCCGCTGCTACTGGAAGG	ZNRF2	ENSG00000180233	-0.661575626689147	[]	[]	-1	hSpCas9	negative selection	3692217
30285383	30285406	7	-	26780180	A375	viability (Avana lentiGuide)	GCGCGTGCGGCCGTTAGCGGCGG	ZNRF2	ENSG00000180233	9.62685138899276	[]	[]	6	hSpCas9	negative selection	3692218
30285355	30285378	7	+	26780180	A375	viability (Avana lentiGuide)	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	-4.79139356333287	[]	[]	-7	hSpCas9	negative selection	3692219
30285434	30285457	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.2864190287523988	[5]	[6,6]	8	hSpCas9	positive selection	3800821
30285421	30285444	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCTACCTTCCAGTAGCAGCGG	ZNRF2	ENSG00000180233	-0.5753238433636175	[5]	[2,3]	-7	hSpCas9	positive selection	3800822
30285591	30285614	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCAGCCGCTCCCTCGGCGGGG	ZNRF2	ENSG00000180233	0.07877034064411109	[3]	[3,3]	2	hSpCas9	positive selection	3800823
30285427	30285450	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCCTCCGCTGCTACTGGAAGG	ZNRF2	ENSG00000180233	0.20822106352307132	[4]	[5,5]	6	hSpCas9	positive selection	3800824
30285383	30285406	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCGTGCGGCCGTTAGCGGCGG	ZNRF2	ENSG00000180233	0.31018844120816524	[4]	[5,5]	8	hSpCas9	positive selection	3800825
30285355	30285378	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	-0.05723300499314443	[3]	[3,2]	-1	hSpCas9	positive selection	3800826
30285434	30285457	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.07099866393992285	[6]	[5,5]	1	hSpCas9	positive selection	3909428
30285421	30285444	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCTACCTTCCAGTAGCAGCGG	ZNRF2	ENSG00000180233	-0.8818421917931782	[5]	[1,2]	-8	hSpCas9	positive selection	3909429
30285591	30285614	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCAGCCGCTCCCTCGGCGGGG	ZNRF2	ENSG00000180233	-0.2679549484263075	[4]	[2,3]	-4	hSpCas9	positive selection	3909430
30285427	30285450	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCCTCCGCTGCTACTGGAAGG	ZNRF2	ENSG00000180233	0.06341964811926225	[4]	[4,3]	1	hSpCas9	positive selection	3909431
30285383	30285406	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCGTGCGGCCGTTAGCGGCGG	ZNRF2	ENSG00000180233	-0.28742917945862256	[5]	[4,2]	-4	hSpCas9	positive selection	3909432
30285355	30285378	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	-0.004567807484427644	[3]	[3,2]	0	hSpCas9	positive selection	3909433
30285685	30285708	7	-	26780180	A375	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.00534276206510201	[]	[]	0	hSpCas9	negative selection	4017382
30285396	30285419	7	-	26780180	A375	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.812729467025994	[]	[]	3	hSpCas9	negative selection	4017383
30355765	30355788	7	+	26780180	A375	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	1.38557427391746	[]	[]	7	hSpCas9	negative selection	4017384
30355768	30355791	7	-	26780180	A375	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.435901402240081	[]	[]	1	hSpCas9	negative selection	4017385
30323719	30323742	7	-	26780180	A375	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.875954595706619	[]	[]	3	hSpCas9	negative selection	4017386
30285685	30285708	7	-	26780180	HT29	viability (GeCKOv2 library)	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.767274309346873	[]	[]	3	hSpCas9	negative selection	4125348
30285396	30285419	7	-	26780180	HT29	viability (GeCKOv2 library)	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	1.14845502703771	[]	[]	5	hSpCas9	negative selection	4125349
30355765	30355788	7	+	26780180	HT29	viability (GeCKOv2 library)	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	2.01694765654159	[]	[]	9	hSpCas9	negative selection	4125350
30355768	30355791	7	-	26780180	HT29	viability (GeCKOv2 library)	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.645073278167629	[]	[]	2	hSpCas9	negative selection	4125351
30323719	30323742	7	-	26780180	HT29	viability (GeCKOv2 library)	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.817521278966794	[]	[]	3	hSpCas9	negative selection	4125352
30323716	30323739	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGCCACGAATAACCTATAATGG	ZNRF2	ENSG00000180233	-0.16759985123990967	[2]	[1,0]	-4	hSpCas9	positive selection	4185656
30355765	30355788	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.42785986494238354	[2]	[1,0]	-8	hSpCas9	positive selection	4185657
30355730	30355753	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	-0.16863088833687812	[2]	[1,0]	-4	hSpCas9	positive selection	4185658
30323719	30323742	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.28774932355676797	[3]	[1,4]	7	hSpCas9	positive selection	4185660
30323716	30323739	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGCCACGAATAACCTATAATGG	ZNRF2	ENSG00000180233	1.1805416062013092	[3]	[2,3,4,3]	8	hSpCas9	positive selection	4249678
30355765	30355788	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.4342537734455866	[2]	[1,0,0,0]	-6	hSpCas9	positive selection	4249679
30355730	30355753	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.6551673901759827	[1]	[0,0,1,0]	4	hSpCas9	positive selection	4249680
30323719	30323742	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.1370860842431899	[3]	[0,3,4,0]	1	hSpCas9	positive selection	4249682
30285685	30285708	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.6802461165307725	[3]	[4,4]	9	hSpCas9	positive selection	4310555
30285396	30285419	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.09315817148924357	[2]	[3,1]	2	hSpCas9	positive selection	4310556
30323719	30323742	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.052641032176971636	[1]	[1,1]	1	hSpCas9	positive selection	4310557
30355765	30355788	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.19817282929789712	[2]	[3,1]	4	hSpCas9	positive selection	4374803
30355768	30355791	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.07577059934755537	[1]	[1,0]	1	hSpCas9	positive selection	4374804
30285442	30285464	7	+	27760321	OCIAML3	viability	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	-0.0006196382924718094	[484,377]	[334,334]	0	hSpCas9	negative selection	4458160
30285638	30285660	7	-	27760321	OCIAML3	viability	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	0.3647662929124065	[857,661]	[596,971]	4	hSpCas9	negative selection	4458161
30285671	30285693	7	+	27760321	OCIAML3	viability	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	0.9358927695811793	[737,519]	[945,910]	9	hSpCas9	negative selection	4458162
30323653	30323675	7	-	27760321	OCIAML3	viability	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	0.6611815669206342	[136,84]	[138,129]	7	hSpCas9	negative selection	4458163
30323675	30323697	7	-	27760321	OCIAML3	viability	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	0.2943608446357451	[475,382]	[393,429]	3	hSpCas9	negative selection	4458164
30285442	30285464	7	+	27760321	OCIAML2	viability	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	0.028226451116394692	[484,377]	[299,423]	0	hSpCas9	negative selection	4541623
30285638	30285660	7	-	27760321	OCIAML2	viability	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	-0.3942232875541337	[857,661]	[406,539]	-5	hSpCas9	negative selection	4541624
30285671	30285693	7	+	27760321	OCIAML2	viability	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	0.6533044894648302	[737,519]	[693,919]	8	hSpCas9	negative selection	4541625
30323653	30323675	7	-	27760321	OCIAML2	viability	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	1.3314395545008555	[136,84]	[230,210]	9	hSpCas9	negative selection	4541626
30323675	30323697	7	-	27760321	OCIAML2	viability	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	0.7907174132967892	[475,382]	[516,703]	9	hSpCas9	negative selection	4541627
30285442	30285464	7	+	27760321	MV411	viability	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	0.12123043988031834	[484,377]	[275,354]	0	hSpCas9	negative selection	4625086
30285638	30285660	7	-	27760321	MV411	viability	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	0.5358518530849266	[857,661]	[481,1081]	4	hSpCas9	negative selection	4625087
30285671	30285693	7	+	27760321	MV411	viability	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	0.5015056800011787	[737,519]	[571,594]	3	hSpCas9	negative selection	4625088
30323653	30323675	7	-	27760321	MV411	viability	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	0.2341203952402311	[136,84]	[61,118]	1	hSpCas9	negative selection	4625089
30323675	30323697	7	-	27760321	MV411	viability	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	0.32918027891505214	[475,382]	[202,580]	2	hSpCas9	negative selection	4625090
30285442	30285464	7	+	27760321	HL60	viability	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	0.5639807036057357	[484,377]	[417,622]	6	hSpCas9	negative selection	4708549
30285638	30285660	7	-	27760321	HL60	viability	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	-0.2772707670682725	[857,661]	[575,436]	-3	hSpCas9	negative selection	4708550
30285671	30285693	7	+	27760321	HL60	viability	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	0.5384777501615913	[737,519]	[824,645]	6	hSpCas9	negative selection	4708551
30323653	30323675	7	-	27760321	HL60	viability	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	0.8280614228514824	[136,84]	[88,231]	8	hSpCas9	negative selection	4708552
30323675	30323697	7	-	27760321	HL60	viability	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	-0.44022357085484043	[475,382]	[244,269]	-5	hSpCas9	negative selection	4708553
30285442	30285464	7	+	27760321	HT1080	viability	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	0.8457893499200513	[377,294]	[154,334]	4	hSpCas9	negative selection	4792012
30285638	30285660	7	-	27760321	HT1080	viability	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	0.4375947603481105	[661,516]	[192,454]	2	hSpCas9	negative selection	4792013
30285671	30285693	7	+	27760321	HT1080	viability	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	-0.5498861674811386	[519,405]	[167,79]	-2	hSpCas9	negative selection	4792014
30323653	30323675	7	-	27760321	HT1080	viability	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	2.806308306183785	[84,66]	[209,213]	9	hSpCas9	negative selection	4792015
30323675	30323697	7	-	27760321	HT1080	viability	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	1.5973792128154878	[382,298]	[306,524]	8	hSpCas9	negative selection	4792016
30285442	30285464	7	+	27760321	HT29	viability after 7 days	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	0.41207517850223996	[377,294]	[720,516,510]	6	hSpCas9	negative selection	4875475
30285638	30285660	7	-	27760321	HT29	viability after 7 days	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	-0.2861624907711075	[661,516]	[747,674,463]	-4	hSpCas9	negative selection	4875476
30285671	30285693	7	+	27760321	HT29	viability after 7 days	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	0.692105417530517	[519,405]	[1006,812,1066]	9	hSpCas9	negative selection	4875477
30323653	30323675	7	-	27760321	HT29	viability after 7 days	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	0.5892957560521956	[84,66]	[187,145,113]	8	hSpCas9	negative selection	4875478
30323675	30323697	7	-	27760321	HT29	viability after 7 days	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	0.19972808298603223	[382,298]	[492,499,514]	3	hSpCas9	negative selection	4875479
30285442	30285464	7	+	27760321	HT29	viability after 25 days	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	0.5390883388972161	[377,294]	[601,423,656]	6	hSpCas9	negative selection	4958938
30285638	30285660	7	-	27760321	HT29	viability after 25 days	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	-0.14953432773832043	[661,516]	[664,584,562]	-1	hSpCas9	negative selection	4958939
30285671	30285693	7	+	27760321	HT29	viability after 25 days	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	1.1992950332638777	[519,405]	[1355,1092,1181]	9	hSpCas9	negative selection	4958940
30323653	30323675	7	-	27760321	HT29	viability after 25 days	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	0.2837690617392974	[84,66]	[139,69,104]	3	hSpCas9	negative selection	4958941
30323675	30323697	7	-	27760321	HT29	viability after 25 days	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	0.8226650628224482	[382,298]	[353,853,901]	8	hSpCas9	negative selection	4958942
30285442	30285464	7	+	27760321	HT29	viability after 22 days	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	0.5434528223821531	[377,294]	[541,544,614]	6	hSpCas9	negative selection	5042401
30285638	30285660	7	-	27760321	HT29	viability after 22 days	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	-0.08359240716679606	[661,516]	[940,585,391]	-1	hSpCas9	negative selection	5042402
30285671	30285693	7	+	27760321	HT29	viability after 22 days	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	1.067867572031637	[519,405]	[948,1498,920]	9	hSpCas9	negative selection	5042403
30323653	30323675	7	-	27760321	HT29	viability after 22 days	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	1.1251606027342955	[84,66]	[120,179,276]	9	hSpCas9	negative selection	5042404
30323675	30323697	7	-	27760321	HT29	viability after 22 days	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	0.41924846149250683	[382,298]	[314,765,505]	4	hSpCas9	negative selection	5042405
30285442	30285464	7	+	27760321	HT29	viability after 19 days	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	0.8666411432875767	[377,294]	[490,496,1079]	8	hSpCas9	negative selection	5125864
30285638	30285660	7	-	27760321	HT29	viability after 19 days	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	-0.44387803172005097	[661,516]	[297,485,674]	-4	hSpCas9	negative selection	5125865
30285671	30285693	7	+	27760321	HT29	viability after 19 days	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	0.9361739394247857	[519,405]	[953,855,1214]	8	hSpCas9	negative selection	5125866
30323653	30323675	7	-	27760321	HT29	viability after 19 days	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	1.7172382220511413	[84,66]	[215,578,63]	9	hSpCas9	negative selection	5125867
30323675	30323697	7	-	27760321	HT29	viability after 19 days	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	0.47736727893737413	[382,298]	[497,748,382]	5	hSpCas9	negative selection	5125868
30285442	30285464	7	+	27760321	HT29	viability after 16 days	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	0.8716735890579477	[377,294]	[810,383,890]	9	hSpCas9	negative selection	5209327
30285638	30285660	7	-	27760321	HT29	viability after 16 days	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	-0.3191954314083096	[661,516]	[576,391,624]	-3	hSpCas9	negative selection	5209328
30285671	30285693	7	+	27760321	HT29	viability after 16 days	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	1.1212641786030058	[519,405]	[1144,1248,984]	9	hSpCas9	negative selection	5209329
30323653	30323675	7	-	27760321	HT29	viability after 16 days	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	1.432818991329726	[84,66]	[383,138,182]	9	hSpCas9	negative selection	5209330
30323675	30323697	7	-	27760321	HT29	viability after 16 days	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	0.33778089098029834	[382,298]	[652,273,540]	4	hSpCas9	negative selection	5209331
30285442	30285464	7	+	27760321	HT29	viability after 13 days	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	0.30893585613125585	[377,294]	[373,474,594]	4	hSpCas9	negative selection	5292790
30285638	30285660	7	-	27760321	HT29	viability after 13 days	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	-0.036977745343251156	[661,516]	[802,693,511]	0	hSpCas9	negative selection	5292791
30285671	30285693	7	+	27760321	HT29	viability after 13 days	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	1.0353201425594325	[519,405]	[1340,928,1035]	9	hSpCas9	negative selection	5292792
30323653	30323675	7	-	27760321	HT29	viability after 13 days	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	0.11604788082898931	[84,66]	[137,91,58]	1	hSpCas9	negative selection	5292793
30323675	30323697	7	-	27760321	HT29	viability after 13 days	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	0.5623286235408255	[382,298]	[408,762,580]	7	hSpCas9	negative selection	5292794
30285442	30285464	7	+	27760321	HT29	viability after 10 days	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	0.8439665256769278	[377,294]	[738,694,824]	9	hSpCas9	negative selection	5376253
30285638	30285660	7	-	27760321	HT29	viability after 10 days	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	-0.17302870055903852	[661,516]	[527,658,768]	-2	hSpCas9	negative selection	5376254
30285671	30285693	7	+	27760321	HT29	viability after 10 days	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	0.9783840481005512	[519,405]	[1101,1359,964]	9	hSpCas9	negative selection	5376255
30323653	30323675	7	-	27760321	HT29	viability after 10 days	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	0.4839235418078933	[84,66]	[230,121,46]	6	hSpCas9	negative selection	5376256
30323675	30323697	7	-	27760321	HT29	viability after 10 days	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	0.6774016063079488	[382,298]	[589,528,913]	8	hSpCas9	negative selection	5376257
30285442	30285464	7	+	27760321	MOLM13	viability	GGAGGCGCCAATGGGACCGCGG	ZNRF2	ENSG00000180233	0.3663771022718545	[484,377]	[611,55]	2	hSpCas9	negative selection	5459716
30285638	30285660	7	-	27760321	MOLM13	viability	AAGGGGGACTGCGCCGCGCGGG	ZNRF2	ENSG00000180233	-0.848060537021919	[857,661]	[283,195]	-5	hSpCas9	negative selection	5459717
30285671	30285693	7	+	27760321	MOLM13	viability	ACAGCAGCAGCGGCCCGTACGG	ZNRF2	ENSG00000180233	0.8108514574409035	[737,519]	[773,480]	5	hSpCas9	negative selection	5459718
30323653	30323675	7	-	27760321	MOLM13	viability	ATACAAATTTTGAGCATACAGG	ZNRF2	ENSG00000180233	-1.2381620690470885	[136,84]	[10,38]	-6	hSpCas9	negative selection	5459719
30323675	30323697	7	-	27760321	MOLM13	viability	TGCAAATCCATTTCATCTGAGG	ZNRF2	ENSG00000180233	0.514375175483755	[475,382]	[455,248]	3	hSpCas9	negative selection	5459720
30284961	30284984	7	+	27661255	K562	viability	GGAGGCGGTGCCGAGATCGGGGG	ZNRF2	ENSG00000180233	0.16535943476939746	[563,513]	[501,467]	6	dCas9-KRAB	negative selection	5525990
30284992	30285015	7	+	27661255	K562	viability	GCGGCAGCAGAGAGCGGTAGCGG	ZNRF2	ENSG00000180233	0.03897199644888494	[455,450]	[422,328]	1	dCas9-KRAB	negative selection	5525991
30285355	30285378	7	+	27661255	K562	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	0.17276339933068852	[1030,1111]	[1152,801]	6	dCas9-KRAB	negative selection	5525992
30284635	30284658	7	-	27661255	K562	viability	GGCCCCGCGCCGGAAGGCCGCGG	ZNRF2	ENSG00000180233	-0.20019372888960285	[561,498]	[387,353]	-6	dCas9-KRAB	negative selection	5525993
30284971	30284994	7	-	27661255	K562	viability	GCGCTCGGCGCCCCCGATCTCGG	ZNRF2	ENSG00000180233	0.448352048482233	[198,251]	[227,258]	9	dCas9-KRAB	negative selection	5525994
30285051	30285074	7	-	27661255	K562	viability	GGGCGGCTCAAGTGGCCGTGCGG	ZNRF2	ENSG00000180233	-0.034250881130968414	[1206,1329]	[1017,961]	-1	dCas9-KRAB	negative selection	5525995
30285059	30285082	7	-	27661255	K562	viability	GCAGGAAGGGGCGGCTCAAGTGG	ZNRF2	ENSG00000180233	0.08516409643581879	[480,533]	[540,333]	3	dCas9-KRAB	negative selection	5525996
30285685	30285708	7	-	27260156	BXPC3	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.33115894798231066	[588]	[690,768,957,675]	7	hSpCas9	negative selection	5583015
30285396	30285419	7	-	27260156	BXPC3	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.05158219286652421	[329]	[279,366,441,346]	1	hSpCas9	negative selection	5583016
30323719	30323742	7	-	27260156	BXPC3	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.2488348098951505	[186]	[171,272,190,303]	5	hSpCas9	negative selection	5583017
30355765	30355788	7	+	27260156	BXPC3	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.22906235441854833	[439]	[356,353,362,513]	-5	hSpCas9	negative selection	5647263
30355768	30355791	7	-	27260156	BXPC3	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.14024708795325402	[95]	[129,92,127,86]	3	hSpCas9	negative selection	5647264
30285685	30285708	7	-	27260156	A673	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.20744902135394055	[588]	[906,768,896,695]	5	hSpCas9	negative selection	5704266
30285396	30285419	7	-	27260156	A673	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	-0.03668802739381105	[329]	[382,457,355,342]	-1	hSpCas9	negative selection	5704267
30323719	30323742	7	-	27260156	A673	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.36365817211267504	[186]	[282,269,292,309]	8	hSpCas9	negative selection	5704268
30355765	30355788	7	+	27260156	A673	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.10646950661910083	[439]	[575,474,441,478]	-3	hSpCas9	negative selection	5768514
30355768	30355791	7	-	27260156	A673	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.20319256307490408	[95]	[94,99,146,187]	5	hSpCas9	negative selection	5768515
30285685	30285708	7	-	27260156	A375	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.6273501693185735	[588]	[1137,1193,903,1032]	8	hSpCas9	negative selection	5825517
30285396	30285419	7	-	27260156	A375	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.2869179033227576	[329]	[580,468,453,385]	4	hSpCas9	negative selection	5825518
30323719	30323742	7	-	27260156	A375	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.4267687395429077	[186]	[295,500,239,178]	6	hSpCas9	negative selection	5825519
30355765	30355788	7	+	27260156	A375	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.09818208228572994	[439]	[474,684,621,446]	1	hSpCas9	negative selection	5889765
30355768	30355791	7	-	27260156	A375	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.6362075350098366	[95]	[170,202,240,94]	8	hSpCas9	negative selection	5889766
30285685	30285708	7	-	27260156	COLO741	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.32243466410497995	[588]	[1086,984,773]	6	hSpCas9	negative selection	5946768
30285396	30285419	7	-	27260156	COLO741	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.06454968538918437	[329]	[634,416,296]	1	hSpCas9	negative selection	5946769
30323719	30323742	7	-	27260156	COLO741	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.4423324293309334	[186]	[298,484,196]	8	hSpCas9	negative selection	5946770
30355765	30355788	7	+	27260156	COLO741	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.21096132851165655	[439]	[364,496,576]	-4	hSpCas9	negative selection	6011016
30355768	30355791	7	-	27260156	COLO741	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.04349833234026512	[95]	[131,142,105]	0	hSpCas9	negative selection	6011017
30285685	30285708	7	-	27260156	CAL120	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.24191414335606715	[588]	[1038,618,965]	3	hSpCas9	negative selection	6068019
30285396	30285419	7	-	27260156	CAL120	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	-0.332133539736728	[329]	[396,258,332]	-5	hSpCas9	negative selection	6068020
30323719	30323742	7	-	27260156	CAL120	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.8375358058337835	[186]	[634,435,212]	9	hSpCas9	negative selection	6068021
30355765	30355788	7	+	27260156	CAL120	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.2344361194713495	[439]	[878,416,670]	3	hSpCas9	negative selection	6132267
30355768	30355791	7	-	27260156	CAL120	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.46269603949424143	[95]	[226,43,230]	7	hSpCas9	negative selection	6132268
30285685	30285708	7	-	27260156	CADOES1	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.1259737452089949	[588]	[417,637,499,844]	2	hSpCas9	negative selection	6189270
30285396	30285419	7	-	27260156	CADOES1	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.10419009074965635	[329]	[393,379,306,234]	1	hSpCas9	negative selection	6189271
30323719	30323742	7	-	27260156	CADOES1	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.08192910874029025	[186]	[177,263,123,169]	1	hSpCas9	negative selection	6189272
30355765	30355788	7	+	27260156	CADOES1	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.08880566629554086	[439]	[348,298,456,435]	-1	hSpCas9	negative selection	6253518
30355768	30355791	7	-	27260156	CADOES1	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.5578354220812611	[95]	[119,168,126,108]	8	hSpCas9	negative selection	6253519
30285685	30285708	7	-	27260156	EWS502	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.4520840518260382	[588]	[765,820,970,866]	7	hSpCas9	negative selection	6310521
30285396	30285419	7	-	27260156	EWS502	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.4197626091342056	[329]	[710,502,248,363]	7	hSpCas9	negative selection	6310522
30323719	30323742	7	-	27260156	EWS502	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.15483158545453013	[186]	[153,158,322,259]	2	hSpCas9	negative selection	6310523
30355765	30355788	7	+	27260156	EWS502	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.06821519770479172	[439]	[406,504,429,628]	1	hSpCas9	negative selection	6374769
30355768	30355791	7	-	27260156	EWS502	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.8292303926131248	[95]	[313,92,160,137]	9	hSpCas9	negative selection	6374770
30285685	30285708	7	-	27260156	EW8	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.3974154933992196	[588]	[660,610,589,660]	7	hSpCas9	negative selection	6431772
30285396	30285419	7	-	27260156	EW8	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.007052754758256952	[329]	[276,234,291,266]	0	hSpCas9	negative selection	6431773
30323719	30323742	7	-	27260156	EW8	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.41690667346092325	[186]	[217,240,170,185]	7	hSpCas9	negative selection	6431774
30355765	30355788	7	+	27260156	EW8	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.17572292270403805	[439]	[642,403,294,312]	3	hSpCas9	negative selection	6496020
30355768	30355791	7	-	27260156	EW8	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.9035932242744209	[95]	[99,120,105,255]	9	hSpCas9	negative selection	6496021
30285685	30285708	7	-	27260156	CORL105	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.3429707146732655	[588]	[748,850,839,1047]	6	hSpCas9	negative selection	6553023
30285396	30285419	7	-	27260156	CORL105	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	-0.0440089446615225	[329]	[428,324,445,312]	-1	hSpCas9	negative selection	6553024
30323719	30323742	7	-	27260156	CORL105	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.3047770595413972	[186]	[344,308,283,147]	5	hSpCas9	negative selection	6553025
30355765	30355788	7	+	27260156	CORL105	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.08348138482630464	[439]	[431,604,501,403]	-1	hSpCas9	negative selection	6617271
30355768	30355791	7	-	27260156	CORL105	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.07000695415370828	[95]	[100,143,62,153]	1	hSpCas9	negative selection	6617272
30285685	30285708	7	-	27260156	HS294T	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.3268936444485568	[588]	[269,248,351,270]	4	hSpCas9	negative selection	6674274
30285396	30285419	7	-	27260156	HS294T	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.3299807978055451	[329]	[178,192,100,165]	4	hSpCas9	negative selection	6674275
30323719	30323742	7	-	27260156	HS294T	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	-0.09065247805096455	[186]	[50,97,69,49]	-1	hSpCas9	negative selection	6674276
30355765	30355788	7	+	27260156	HS294T	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.12597976730361932	[439]	[190,155,99,175]	-2	hSpCas9	negative selection	6738522
30355768	30355791	7	-	27260156	HS294T	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	-0.4629008585677865	[95]	[17,36,16,37]	-6	hSpCas9	negative selection	6738523
30285685	30285708	7	-	27260156	HCC44	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.43676359228867984	[588]	[932,861,828,968]	7	hSpCas9	negative selection	6795525
30285396	30285419	7	-	27260156	HCC44	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.31485273288136173	[329]	[371,549,503,414]	5	hSpCas9	negative selection	6795526
30323719	30323742	7	-	27260156	HCC44	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.46366510147586426	[186]	[246,247,283,382]	7	hSpCas9	negative selection	6795527
30355765	30355788	7	+	27260156	HCC44	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.23976629505176889	[439]	[464,441,398,374]	-4	hSpCas9	negative selection	6859773
30355768	30355791	7	-	27260156	HCC44	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.3478530708134928	[95]	[137,131,151,132]	5	hSpCas9	negative selection	6859774
30285685	30285708	7	-	27260156	G402	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.6234297640986728	[588]	[1329,1019,1279,834]	7	hSpCas9	negative selection	6916776
30285396	30285419	7	-	27260156	G402	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.32403781346609006	[329]	[575,614,459,385]	4	hSpCas9	negative selection	6916777
30323719	30323742	7	-	27260156	G402	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.6477032968126698	[186]	[717,167,340,247]	7	hSpCas9	negative selection	6916778
30355765	30355788	7	+	27260156	G402	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.5402918574962626	[439]	[1833,298,580,541]	6	hSpCas9	negative selection	6981024
30355768	30355791	7	-	27260156	G402	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.4392993414387447	[95]	[188,158,193,99]	5	hSpCas9	negative selection	6981025
30285685	30285708	7	-	27260156	L33	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.43133666570778956	[588]	[825,386,439,705]	8	hSpCas9	negative selection	7038027
30285396	30285419	7	-	27260156	L33	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.5172180728929762	[329]	[441,187,261,570]	9	hSpCas9	negative selection	7038028
30323719	30323742	7	-	27260156	L33	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	-0.025278488181454284	[186]	[267,70,90,146]	0	hSpCas9	negative selection	7038029
30355765	30355788	7	+	27260156	L33	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.2928443824871952	[439]	[413,146,210,326]	-6	hSpCas9	negative selection	7102275
30355768	30355791	7	-	27260156	L33	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	-0.050287993242859486	[95]	[96,40,35,115]	-1	hSpCas9	negative selection	7102276
30285685	30285708	7	-	27260156	K562	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.3215044561130251	[588]	[1036,466,836,328]	4	hSpCas9	negative selection	7159278
30285396	30285419	7	-	27260156	K562	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	-0.05565398691036427	[329]	[240,416,98,362]	0	hSpCas9	negative selection	7159279
30323719	30323742	7	-	27260156	K562	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.02556481870174032	[186]	[127,338,133,88]	0	hSpCas9	negative selection	7159280
30355765	30355788	7	+	27260156	K562	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.3107136723806625	[439]	[428,567,528,416]	4	hSpCas9	negative selection	7223526
30355768	30355791	7	-	27260156	K562	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.6373172501852615	[95]	[88,169,127,139]	7	hSpCas9	negative selection	7223527
30285685	30285708	7	-	27260156	HT29	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.125958370891171	[588]	[882,771,729,745]	2	hSpCas9	negative selection	7280529
30285396	30285419	7	-	27260156	HT29	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.26445074692059634	[329]	[468,610,443,417]	5	hSpCas9	negative selection	7280530
30323719	30323742	7	-	27260156	HT29	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.47629213048586005	[186]	[346,313,360,250]	8	hSpCas9	negative selection	7280531
30355765	30355788	7	+	27260156	HT29	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.09957780437817194	[439]	[627,563,347,471]	-2	hSpCas9	negative selection	7344777
30355768	30355791	7	-	27260156	HT29	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.020367137440861605	[95]	[168,62,114,123]	0	hSpCas9	negative selection	7344778
30285685	30285708	7	-	27260156	MHHES1	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.4616698205734651	[588]	[1131,1146,911,572]	7	hSpCas9	negative selection	7401780
30285396	30285419	7	-	27260156	MHHES1	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	-0.21199359901201653	[329]	[458,375,337,162]	-4	hSpCas9	negative selection	7401781
30323719	30323742	7	-	27260156	MHHES1	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	-0.06562787974362227	[186]	[269,297,202,76]	-1	hSpCas9	negative selection	7401782
30355765	30355788	7	+	27260156	MHHES1	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.08180065177927688	[439]	[404,716,356,412]	-1	hSpCas9	negative selection	7466028
30355768	30355791	7	-	27260156	MHHES1	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	-0.1188022470839547	[95]	[94,135,83,86]	-2	hSpCas9	negative selection	7466029
30285685	30285708	7	-	27260156	MEWO	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.40687849318277985	[588]	[787,671,742]	8	hSpCas9	negative selection	7523031
30285396	30285419	7	-	27260156	MEWO	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	-0.07279596409720113	[329]	[422,220,261]	-1	hSpCas9	negative selection	7523032
30323719	30323742	7	-	27260156	MEWO	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.004658220025632431	[186]	[182,166,177]	0	hSpCas9	negative selection	7523033
30355765	30355788	7	+	27260156	MEWO	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.15025098312749446	[439]	[371,354,385]	-3	hSpCas9	negative selection	7587279
30355768	30355791	7	-	27260156	MEWO	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.22705062541073762	[95]	[123,104,89]	5	hSpCas9	negative selection	7587280
30285685	30285708	7	-	27260156	LNCAPCLONEFGC	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.2995243410172284	[588]	[552,664,658,750]	5	hSpCas9	negative selection	7644282
30285396	30285419	7	-	27260156	LNCAPCLONEFGC	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.19570147333340027	[329]	[330,283,427,342]	3	hSpCas9	negative selection	7644283
30323719	30323742	7	-	27260156	LNCAPCLONEFGC	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.5018714139289869	[186]	[245,259,233,216]	7	hSpCas9	negative selection	7644284
30355765	30355788	7	+	27260156	LNCAPCLONEFGC	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.10211065208403276	[439]	[305,267,443,485]	-2	hSpCas9	negative selection	7708530
30355768	30355791	7	-	27260156	LNCAPCLONEFGC	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.5666290947951804	[95]	[28,141,248,113]	8	hSpCas9	negative selection	7708531
30285685	30285708	7	-	27260156	PANC0327	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.4810275877700328	[588]	[591,694,747,878]	7	hSpCas9	negative selection	7765533
30285396	30285419	7	-	27260156	PANC0327	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.42439095595777143	[329]	[374,351,280,568]	6	hSpCas9	negative selection	7765534
30323719	30323742	7	-	27260156	PANC0327	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.06930919580633987	[186]	[155,279,163,81]	1	hSpCas9	negative selection	7765535
30355765	30355788	7	+	27260156	PANC0327	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.39043175026364113	[439]	[334,543,324,825]	6	hSpCas9	negative selection	7829781
30355768	30355791	7	-	27260156	PANC0327	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	-1.302896144595325	[95]	[44,42,23,25]	-9	hSpCas9	negative selection	7829782
30285685	30285708	7	-	27260156	NCIH2009	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.8876672639312155	[588]	[1674,1369,1552]	9	hSpCas9	negative selection	7886784
30285396	30285419	7	-	27260156	NCIH2009	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.6238357850704138	[329]	[740,559,837]	8	hSpCas9	negative selection	7886785
30323719	30323742	7	-	27260156	NCIH2009	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.1082590099526679	[186]	[320,291,238]	1	hSpCas9	negative selection	7886786
30355765	30355788	7	+	27260156	NCIH2009	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.12824797782112413	[439]	[867,413,775]	1	hSpCas9	negative selection	7951032
30355768	30355791	7	-	27260156	NCIH2009	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.21522968389130082	[95]	[115,100,242]	3	hSpCas9	negative selection	7951033
30285685	30285708	7	-	27260156	NCIH1373	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	1.1065727952380824	[588]	[1994,1193,1794,199]	9	hSpCas9	negative selection	8008035
30285396	30285419	7	-	27260156	NCIH1373	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.1274821560676262	[329]	[646,355,393,65]	1	hSpCas9	negative selection	8008036
30323719	30323742	7	-	27260156	NCIH1373	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.21757252230674973	[186]	[582,109,194,38]	2	hSpCas9	negative selection	8008037
30355765	30355788	7	+	27260156	NCIH1373	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.11673442021911305	[439]	[775,541,315,142]	1	hSpCas9	negative selection	8072283
30355768	30355791	7	-	27260156	NCIH1373	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	1.4091493989639567	[95]	[456,63,362,80]	9	hSpCas9	negative selection	8072284
30285685	30285708	7	-	27260156	PATU8902	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.6194894963305961	[588]	[1516,957,920,1780]	6	hSpCas9	negative selection	8129286
30285396	30285419	7	-	27260156	PATU8902	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.7457541324644009	[329]	[714,818,567,1062]	7	hSpCas9	negative selection	8129287
30323719	30323742	7	-	27260156	PATU8902	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	-0.005932628336477341	[186]	[476,133,251,158]	0	hSpCas9	negative selection	8129288
30355765	30355788	7	+	27260156	PATU8902	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.038891594984262645	[439]	[709,726,293,900]	0	hSpCas9	negative selection	8193534
30355768	30355791	7	-	27260156	PATU8902	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.9155705708225848	[95]	[146,164,302,396]	8	hSpCas9	negative selection	8193535
30285685	30285708	7	-	27260156	PANC1	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.27675362729369496	[588]	[746,793,510,449]	4	hSpCas9	negative selection	8250537
30285396	30285419	7	-	27260156	PANC1	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.3967250331776876	[329]	[378,449,395,290]	6	hSpCas9	negative selection	8250538
30323719	30323742	7	-	27260156	PANC1	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.38562019963746075	[186]	[222,257,147,214]	6	hSpCas9	negative selection	8250539
30355765	30355788	7	+	27260156	PANC1	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.1349752328192386	[439]	[385,533,418,349]	2	hSpCas9	negative selection	8314785
30355768	30355791	7	-	27260156	PANC1	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.33147847257034435	[95]	[145,114,34,115]	5	hSpCas9	negative selection	8314786
30285685	30285708	7	-	27260156	PANC0813	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.584574506525509	[588]	[1402,1094,812,878]	8	hSpCas9	negative selection	8371788
30285396	30285419	7	-	27260156	PANC0813	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.07992707983130726	[329]	[397,546,257,431]	1	hSpCas9	negative selection	8371789
30323719	30323742	7	-	27260156	PANC0813	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	-0.19140126012397451	[186]	[242,181,144,202]	-3	hSpCas9	negative selection	8371790
30355765	30355788	7	+	27260156	PANC0813	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.17020543615352146	[439]	[403,670,441,321]	-3	hSpCas9	negative selection	8436036
30355768	30355791	7	-	27260156	PANC0813	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.09283123977970531	[95]	[135,137,119,89]	1	hSpCas9	negative selection	8436037
30285685	30285708	7	-	27260156	RDES	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.5704423495504563	[588]	[824,792,1343,1121]	8	hSpCas9	negative selection	8493039
30285396	30285419	7	-	27260156	RDES	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.4104463722223525	[329]	[382,446,572,657]	6	hSpCas9	negative selection	8493040
30323719	30323742	7	-	27260156	RDES	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.3976688425490482	[186]	[234,277,359,261]	6	hSpCas9	negative selection	8493041
30355765	30355788	7	+	27260156	RDES	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.05177765896174523	[439]	[423,465,579,662]	0	hSpCas9	negative selection	8557287
30355768	30355791	7	-	27260156	RDES	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.3788467980099297	[95]	[133,106,185,150]	6	hSpCas9	negative selection	8557288
30285685	30285708	7	-	27260156	PC3	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.3525584121640151	[588]	[500,637,1622,609]	7	hSpCas9	negative selection	8614290
30285396	30285419	7	-	27260156	PC3	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	-0.007975475433343315	[329]	[159,373,631,304]	0	hSpCas9	negative selection	8614291
30323719	30323742	7	-	27260156	PC3	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.41592413005306916	[186]	[162,253,414,238]	8	hSpCas9	negative selection	8614292
30355765	30355788	7	+	27260156	PC3	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.10769917429712299	[439]	[191,450,649,493]	-2	hSpCas9	negative selection	8678538
30355768	30355791	7	-	27260156	PC3	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	-0.5668709147138054	[95]	[30,101,111,37]	-8	hSpCas9	negative selection	8678539
30285685	30285708	7	-	27260156	PATU8988T	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.5218412280096956	[588]	[675,785,654,1179]	8	hSpCas9	negative selection	8735541
30285396	30285419	7	-	27260156	PATU8988T	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	-0.1655721546935056	[329]	[386,173,299,263]	-3	hSpCas9	negative selection	8735542
30323719	30323742	7	-	27260156	PATU8988T	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.3911094589614459	[186]	[205,392,146,215]	6	hSpCas9	negative selection	8735543
30355765	30355788	7	+	27260156	PATU8988T	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.30111480101636473	[439]	[386,517,710,471]	5	hSpCas9	negative selection	8799789
30355768	30355791	7	-	27260156	PATU8988T	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.6520898200054295	[95]	[69,55,207,247]	9	hSpCas9	negative selection	8799790
30285685	30285708	7	-	27260156	T47D	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.14120618740288965	[588]	[818,673,757,783]	3	hSpCas9	negative selection	8856792
30285396	30285419	7	-	27260156	T47D	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	-0.12073379650199756	[329]	[265,312,448,388]	-3	hSpCas9	negative selection	8856793
30323719	30323742	7	-	27260156	T47D	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.33888232998408196	[186]	[232,237,272,363]	7	hSpCas9	negative selection	8856794
30355765	30355788	7	+	27260156	T47D	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.0269084770283934	[439]	[556,487,562,481]	0	hSpCas9	negative selection	8921040
30355768	30355791	7	-	27260156	T47D	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.4822613634724575	[95]	[138,140,160,185]	8	hSpCas9	negative selection	8921041
30285685	30285708	7	-	27260156	SU8686	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.4292099277774197	[588]	[671,763,970,746]	7	hSpCas9	negative selection	8978043
30285396	30285419	7	-	27260156	SU8686	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.46146080805808026	[329]	[238,531,427,643]	7	hSpCas9	negative selection	8978044
30323719	30323742	7	-	27260156	SU8686	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.33372110019645873	[186]	[168,266,178,335]	5	hSpCas9	negative selection	8978045
30355765	30355788	7	+	27260156	SU8686	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.2451743955496113	[439]	[473,448,650,505]	4	hSpCas9	negative selection	9042291
30355768	30355791	7	-	27260156	SU8686	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	-0.44952900523358075	[95]	[80,62,61,71]	-6	hSpCas9	negative selection	9042292
30285685	30285708	7	-	27260156	SKES1	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.4461373098939641	[588]	[680,1151,734,667]	8	hSpCas9	negative selection	9099294
30285396	30285419	7	-	27260156	SKES1	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	-0.05792849623226726	[329]	[289,310,308,343]	-1	hSpCas9	negative selection	9099295
30323719	30323742	7	-	27260156	SKES1	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.32936749639293095	[186]	[186,218,244,270]	7	hSpCas9	negative selection	9099296
30355765	30355788	7	+	27260156	SKES1	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.08267957570207073	[439]	[366,504,513,285]	-2	hSpCas9	negative selection	9163542
30355768	30355791	7	-	27260156	SKES1	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.9637036344671188	[95]	[408,142,140,89]	9	hSpCas9	negative selection	9163543
30285685	30285708	7	-	27260156	TOV112D	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.6151227843544971	[588]	[856,668,1153,871]	9	hSpCas9	negative selection	9220545
30285396	30285419	7	-	27260156	TOV112D	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.25136734134818756	[329]	[403,396,278,491]	5	hSpCas9	negative selection	9220546
30323719	30323742	7	-	27260156	TOV112D	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.43006667425108003	[186]	[386,276,242,122]	7	hSpCas9	negative selection	9220547
30355765	30355788	7	+	27260156	TOV112D	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.5399694614775294	[439]	[131,619,239,283]	-8	hSpCas9	negative selection	9284793
30355768	30355791	7	-	27260156	TOV112D	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.29752324953227194	[95]	[136,119,152,65]	5	hSpCas9	negative selection	9284794
30285685	30285708	7	-	27260156	TC71	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.209609727376951	[588]	[729,690,778,717]	5	hSpCas9	negative selection	9341796
30285396	30285419	7	-	27260156	TC71	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	-0.023265046899995534	[329]	[376,214,421,376]	0	hSpCas9	negative selection	9341797
30323719	30323742	7	-	27260156	TC71	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.27760603154688845	[186]	[198,256,291,221]	6	hSpCas9	negative selection	9341798
30355765	30355788	7	+	27260156	TC71	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	0.03103128262148909	[439]	[469,435,408,623]	0	hSpCas9	negative selection	9406044
30355768	30355791	7	-	27260156	TC71	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	-0.49570284416290233	[95]	[35,126,49,80]	-8	hSpCas9	negative selection	9406045
30285685	30285708	7	-	27260156	TC32	viability	ACCGAGTCCTGCGAGCCGTACGG	ZNRF2	ENSG00000180233	0.3532921931541199	[588]	[763,520,883,709]	6	hSpCas9	negative selection	9463047
30285396	30285419	7	-	27260156	TC32	viability	AGCCCGAGTACGCGCGCGTGCGG	ZNRF2	ENSG00000180233	0.2575693851596115	[329]	[342,269,390,509]	4	hSpCas9	negative selection	9463048
30323719	30323742	7	-	27260156	TC32	viability	TTACCATTATAGGTTATTCGTGG	ZNRF2	ENSG00000180233	0.2986807267982112	[186]	[290,81,295,239]	5	hSpCas9	negative selection	9463049
30355765	30355788	7	+	27260156	TC32	viability	ATGCCTTGAAGAATTGCAGCAGG	ZNRF2	ENSG00000180233	-0.032388575053839394	[439]	[494,263,500,389]	0	hSpCas9	negative selection	9527295
30355768	30355791	7	-	27260156	TC32	viability	CTCCCTGCTGCAATTCTTCAAGG	ZNRF2	ENSG00000180233	0.01785145502922658	[95]	[113,92,96,49]	0	hSpCas9	negative selection	9527296
30285355	30285378	7	+	28162770	P31FUJ	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	-0.4099952063207303	[198]	[175]	-4	hSpCas9	negative selection	10273445
30355766	30355789	7	+	28162770	P31FUJ	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	0.35724917297957737	[282]	[425]	4	hSpCas9	negative selection	10273446
30285424	30285447	7	+	28162770	P31FUJ	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	-0.10791095658656993	[187]	[204]	-1	hSpCas9	negative selection	10273447
30355730	30355753	7	+	28162770	P31FUJ	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.33345410177707757	[413]	[612]	3	hSpCas9	negative selection	10273448
30285709	30285732	7	+	28162770	P31FUJ	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	0.1487888117713232	[359]	[468]	1	hSpCas9	negative selection	10273449
30285434	30285457	7	+	28162770	P31FUJ	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.8580129587712884	[176]	[376]	8	hSpCas9	negative selection	10273450
30285796	30285819	7	-	28162770	P31FUJ	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	1.1692962391569672	[111]	[295]	9	hSpCas9	negative selection	10273451
30285811	30285834	7	-	28162770	P31FUJ	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	0.4459424426273946	[535]	[857]	5	hSpCas9	negative selection	10273452
30285505	30285528	7	-	28162770	P31FUJ	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	1.01855039637178	[154]	[368]	9	hSpCas9	negative selection	10273453
30285355	30285378	7	+	28162770	TF1	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	NaN	[NaN]	[211]	1	hSpCas9	negative selection	10442811
30355766	30355789	7	+	28162770	TF1	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	NaN	[NaN]	[558]	1	hSpCas9	negative selection	10442812
30285424	30285447	7	+	28162770	TF1	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10442813
30355730	30355753	7	+	28162770	TF1	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	NaN	[NaN]	[562]	1	hSpCas9	negative selection	10442814
30285709	30285732	7	+	28162770	TF1	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	NaN	[NaN]	[199]	1	hSpCas9	negative selection	10442815
30285434	30285457	7	+	28162770	TF1	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	NaN	[NaN]	[254]	1	hSpCas9	negative selection	10442816
30285796	30285819	7	-	28162770	TF1	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	NaN	[NaN]	[256]	1	hSpCas9	negative selection	10442817
30285811	30285834	7	-	28162770	TF1	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	NaN	[NaN]	[480]	1	hSpCas9	negative selection	10442818
30285505	30285528	7	-	28162770	TF1	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	NaN	[NaN]	[201]	1	hSpCas9	negative selection	10442819
30285355	30285378	7	+	28162770	SKM1	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	0.2731555350183346	[43]	[93]	2	hSpCas9	negative selection	10612177
30355766	30355789	7	+	28162770	SKM1	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	-0.18641312423088133	[55]	[86]	-2	hSpCas9	negative selection	10612178
30285424	30285447	7	+	28162770	SKM1	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	0.22149994061458086	[48]	[100]	2	hSpCas9	negative selection	10612179
30355730	30355753	7	+	28162770	SKM1	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.09856383448358952	[111]	[211]	0	hSpCas9	negative selection	10612180
30285709	30285732	7	+	28162770	SKM1	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	0.6409702783205402	[73]	[203]	6	hSpCas9	negative selection	10612181
30285434	30285457	7	+	28162770	SKM1	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	-0.06992921146559088	[56]	[95]	0	hSpCas9	negative selection	10612182
30285796	30285819	7	-	28162770	SKM1	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	-0.4199032544506598	[27]	[36]	-3	hSpCas9	negative selection	10612183
30285811	30285834	7	-	28162770	SKM1	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	-0.6355885737911244	[115]	[131]	-5	hSpCas9	negative selection	10612184
30285505	30285528	7	-	28162770	SKM1	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	-1.030588319833423	[51]	[44]	-6	hSpCas9	negative selection	10612185
30285355	30285378	7	+	28162770	SKM1	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	0.2731555350183346	[43]	[93]	2	hSpCas9	negative selection	10781543
30355766	30355789	7	+	28162770	SKM1	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	-0.18641312423088133	[55]	[86]	-2	hSpCas9	negative selection	10781544
30285424	30285447	7	+	28162770	SKM1	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	0.22149994061458086	[48]	[100]	2	hSpCas9	negative selection	10781545
30355730	30355753	7	+	28162770	SKM1	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.09856383448358952	[111]	[211]	0	hSpCas9	negative selection	10781546
30285709	30285732	7	+	28162770	SKM1	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	0.6409702783205402	[73]	[203]	6	hSpCas9	negative selection	10781547
30285434	30285457	7	+	28162770	SKM1	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	-0.06992921146559088	[56]	[95]	0	hSpCas9	negative selection	10781548
30285796	30285819	7	-	28162770	SKM1	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	-0.4199032544506598	[27]	[36]	-3	hSpCas9	negative selection	10781549
30285811	30285834	7	-	28162770	SKM1	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	-0.6355885737911244	[115]	[131]	-5	hSpCas9	negative selection	10781550
30285505	30285528	7	-	28162770	SKM1	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	-1.030588319833423	[51]	[44]	-6	hSpCas9	negative selection	10781551
30285355	30285378	7	+	28162770	PL21	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	-1.1130182707703102	[163]	[32]	-6	hSpCas9	negative selection	10950909
30355766	30355789	7	+	28162770	PL21	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	1.1652058243799328	[208]	[203]	8	hSpCas9	negative selection	10950910
30285424	30285447	7	+	28162770	PL21	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	-1.5032963561116919	[240]	[36]	-7	hSpCas9	negative selection	10950911
30355730	30355753	7	+	28162770	PL21	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	-0.24043297689666132	[455]	[167]	-2	hSpCas9	negative selection	10950912
30285709	30285732	7	+	28162770	PL21	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	-0.10896444004045852	[279]	[112]	-1	hSpCas9	negative selection	10950913
30285434	30285457	7	+	28162770	PL21	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	1.1774195379892367	[191]	[188]	8	hSpCas9	negative selection	10950914
30285796	30285819	7	-	28162770	PL21	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	-0.48791637919593933	[86]	[26]	-3	hSpCas9	negative selection	10950915
30285811	30285834	7	-	28162770	PL21	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	-0.1698099952609856	[335]	[129]	-1	hSpCas9	negative selection	10950916
30285505	30285528	7	-	28162770	PL21	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	-0.37497510027548886	[145]	[48]	-3	hSpCas9	negative selection	10950917
30285355	30285378	7	+	28162770	P31FUJ	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	-0.4099952063207303	[198]	[175]	-4	hSpCas9	negative selection	11120275
30355766	30355789	7	+	28162770	P31FUJ	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	0.35724917297957737	[282]	[425]	4	hSpCas9	negative selection	11120276
30285424	30285447	7	+	28162770	P31FUJ	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	-0.10791095658656993	[187]	[204]	-1	hSpCas9	negative selection	11120277
30355730	30355753	7	+	28162770	P31FUJ	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.33345410177707757	[413]	[612]	3	hSpCas9	negative selection	11120278
30285709	30285732	7	+	28162770	P31FUJ	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	0.1487888117713232	[359]	[468]	1	hSpCas9	negative selection	11120279
30285434	30285457	7	+	28162770	P31FUJ	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.8580129587712884	[176]	[376]	8	hSpCas9	negative selection	11120280
30285796	30285819	7	-	28162770	P31FUJ	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	1.1692962391569672	[111]	[295]	9	hSpCas9	negative selection	11120281
30285811	30285834	7	-	28162770	P31FUJ	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	0.4459424426273946	[535]	[857]	5	hSpCas9	negative selection	11120282
30285505	30285528	7	-	28162770	P31FUJ	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	1.01855039637178	[154]	[368]	9	hSpCas9	negative selection	11120283
30285355	30285378	7	+	28162770	OCIAML5	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	-0.4064407517517301	[104]	[142]	-3	hSpCas9	negative selection	11289641
30355766	30355789	7	+	28162770	OCIAML5	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	0.502849935977276	[146]	[375]	4	hSpCas9	negative selection	11289642
30285424	30285447	7	+	28162770	OCIAML5	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	0.4770570254275692	[79]	[200]	4	hSpCas9	negative selection	11289643
30355730	30355753	7	+	28162770	OCIAML5	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.7130744889444154	[170]	[505]	6	hSpCas9	negative selection	11289644
30285709	30285732	7	+	28162770	OCIAML5	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	-1.022951130067582	[187]	[166]	-6	hSpCas9	negative selection	11289645
30285434	30285457	7	+	28162770	OCIAML5	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.5758868163001323	[138]	[373]	5	hSpCas9	negative selection	11289646
30285796	30285819	7	-	28162770	OCIAML5	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	0.9232271419613087	[77]	[266]	7	hSpCas9	negative selection	11289647
30285811	30285834	7	-	28162770	OCIAML5	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	0.2992980206715872	[225]	[501]	2	hSpCas9	negative selection	11289648
30285505	30285528	7	-	28162770	OCIAML5	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	-0.3602134745343223	[63]	[89]	-3	hSpCas9	negative selection	11289649
30285355	30285378	7	+	28162770	EOL1	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	-0.5608790555997074	[307]	[109]	-4	hSpCas9	negative selection	11459007
30355766	30355789	7	+	28162770	EOL1	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	0.18451587435654496	[313]	[187]	1	hSpCas9	negative selection	11459008
30285424	30285447	7	+	28162770	EOL1	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	0.4140634868086548	[301]	[211]	4	hSpCas9	negative selection	11459009
30355730	30355753	7	+	28162770	EOL1	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.7126286814635954	[731]	[631]	6	hSpCas9	negative selection	11459010
30285709	30285732	7	+	28162770	EOL1	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	-0.7758919465705576	[610]	[187]	-5	hSpCas9	negative selection	11459011
30285434	30285457	7	+	28162770	EOL1	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.33602745143618934	[405]	[269]	3	hSpCas9	negative selection	11459012
30285796	30285819	7	-	28162770	EOL1	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	-0.9119534961465863	[124]	[34]	-6	hSpCas9	negative selection	11459013
30285811	30285834	7	-	28162770	EOL1	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	0.19767099502791208	[474]	[286]	1	hSpCas9	negative selection	11459014
30285505	30285528	7	-	28162770	EOL1	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	-0.6604147291506217	[155]	[51]	-5	hSpCas9	negative selection	11459015
30285355	30285378	7	+	28162770	MOLM13	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	0.9950078076934508	[228]	[329]	7	hSpCas9	negative selection	11628373
30355766	30355789	7	+	28162770	MOLM13	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	0.06421813721567979	[294]	[222]	0	hSpCas9	negative selection	11628374
30285424	30285447	7	+	28162770	MOLM13	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	0.2935592009822652	[245]	[217]	2	hSpCas9	negative selection	11628375
30355730	30355753	7	+	28162770	MOLM13	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.16178625381889922	[679]	[549]	1	hSpCas9	negative selection	11628376
30285709	30285732	7	+	28162770	MOLM13	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	-0.8414386765631499	[455]	[183]	-4	hSpCas9	negative selection	11628377
30285434	30285457	7	+	28162770	MOLM13	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.6171933253886734	[320]	[355]	4	hSpCas9	negative selection	11628378
30285796	30285819	7	-	28162770	MOLM13	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	-0.8364446533280454	[162]	[65]	-4	hSpCas9	negative selection	11628379
30285811	30285834	7	-	28162770	MOLM13	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	0.14435023675123126	[447]	[357]	1	hSpCas9	negative selection	11628380
30285505	30285528	7	-	28162770	MOLM13	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	-0.029610277926238104	[215]	[152]	0	hSpCas9	negative selection	11628381
30285355	30285378	7	+	28162770	HEL	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	0.8952808640165084	[229]	[273]	7	hSpCas9	negative selection	11797739
30355766	30355789	7	+	28162770	HEL	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	0.7665450336147548	[278]	[303]	6	hSpCas9	negative selection	11797740
30285424	30285447	7	+	28162770	HEL	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	-0.7178508832561105	[207]	[80]	-5	hSpCas9	negative selection	11797741
30355730	30355753	7	+	28162770	HEL	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.3873176102764384	[566]	[474]	3	hSpCas9	negative selection	11797742
30285709	30285732	7	+	28162770	HEL	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	-0.5833959910219078	[385]	[164]	-4	hSpCas9	negative selection	11797743
30285434	30285457	7	+	28162770	HEL	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.9029192407789979	[252]	[302]	7	hSpCas9	negative selection	11797744
30285796	30285819	7	-	28162770	HEL	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	0.706303960777823	[110]	[115]	6	hSpCas9	negative selection	11797745
30285811	30285834	7	-	28162770	HEL	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	0.20065445692695638	[340]	[250]	1	hSpCas9	negative selection	11797746
30285505	30285528	7	-	28162770	HEL	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	-0.7495785907784034	[167]	[63]	-5	hSpCas9	negative selection	11797747
30285355	30285378	7	+	28162770	MV411	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	-0.1427965574954959	[172]	[131]	-1	hSpCas9	negative selection	11967105
30355766	30355789	7	+	28162770	MV411	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	0.52853192816156	[171]	[208]	5	hSpCas9	negative selection	11967106
30285424	30285447	7	+	28162770	MV411	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	-0.847719682257565	[187]	[87]	-5	hSpCas9	negative selection	11967107
30355730	30355753	7	+	28162770	MV411	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.5467642167330049	[385]	[474]	5	hSpCas9	negative selection	11967108
30285709	30285732	7	+	28162770	MV411	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	0.13604887028695556	[322]	[298]	1	hSpCas9	negative selection	11967109
30285434	30285457	7	+	28162770	MV411	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	0.3349003920331148	[175]	[186]	3	hSpCas9	negative selection	11967110
30285796	30285819	7	-	28162770	MV411	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	0.24743755078277535	[115]	[115]	2	hSpCas9	negative selection	11967111
30285811	30285834	7	-	28162770	MV411	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	-0.036770878155428344	[301]	[247]	0	hSpCas9	negative selection	11967112
30285505	30285528	7	-	28162770	MV411	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	-0.713568317601361	[145]	[74]	-5	hSpCas9	negative selection	11967113
30285355	30285378	7	+	28162770	MONOMAC1	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	-0.6472025697419994	[96]	[70]	-5	hSpCas9	negative selection	12136471
30355766	30355789	7	+	28162770	MONOMAC1	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	-0.6650232262873567	[147]	[106]	-5	hSpCas9	negative selection	12136472
30285424	30285447	7	+	28162770	MONOMAC1	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	2.0104325232428937	[117]	[544]	9	hSpCas9	negative selection	12136473
30355730	30355753	7	+	28162770	MONOMAC1	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	-0.5353952864443267	[286]	[226]	-4	hSpCas9	negative selection	12136474
30285709	30285732	7	+	28162770	MONOMAC1	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	-0.21895162348799435	[198]	[195]	-2	hSpCas9	negative selection	12136475
30285434	30285457	7	+	28162770	MONOMAC1	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	-0.338212910020248	[117]	[106]	-3	hSpCas9	negative selection	12136476
30285796	30285819	7	-	28162770	MONOMAC1	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	1.0009025305523551	[50]	[116]	8	hSpCas9	negative selection	12136477
30285811	30285834	7	-	28162770	MONOMAC1	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	-0.3418083712735278	[198]	[179]	-3	hSpCas9	negative selection	12136478
30285505	30285528	7	-	28162770	MONOMAC1	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	2.0172822737412117	[63]	[296]	9	hSpCas9	negative selection	12136479
30285355	30285378	7	+	28162770	OCIAML2	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	0.9353625344336756	[24]	[264]	8	hSpCas9	negative selection	12305837
30355766	30355789	7	+	28162770	OCIAML2	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	0.8299246188526342	[33]	[334]	7	hSpCas9	negative selection	12305838
30285424	30285447	7	+	28162770	OCIAML2	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	0.10629535641357685	[29]	[178]	1	hSpCas9	negative selection	12305839
30355730	30355753	7	+	28162770	OCIAML2	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	0.5472920827551009	[89]	[728]	5	hSpCas9	negative selection	12305840
30285709	30285732	7	+	28162770	OCIAML2	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	0.30815594461867213	[50]	[349]	3	hSpCas9	negative selection	12305841
30285434	30285457	7	+	28162770	OCIAML2	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	-0.037670417966055136	[44]	[242]	0	hSpCas9	negative selection	12305842
30285796	30285819	7	-	28162770	OCIAML2	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	-0.06034585593395181	[18]	[100]	0	hSpCas9	negative selection	12305843
30285811	30285834	7	-	28162770	OCIAML2	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	-0.18457876668339535	[56]	[277]	-1	hSpCas9	negative selection	12305844
30285505	30285528	7	-	28162770	OCIAML2	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	0.30609347816177956	[33]	[232]	3	hSpCas9	negative selection	12305845
30285355	30285378	7	+	28162770	OCIAML3	viability	GACATGGGCGCCAAACAGAGCGG	ZNRF2	ENSG00000180233	-0.496396843697741	[49]	[106]	-4	hSpCas9	negative selection	12475203
30355766	30355789	7	+	28162770	OCIAML3	viability	TGCCTTGAAGAATTGCAGCAGGG	ZNRF2	ENSG00000180233	1.237194023687809	[59]	[426]	8	hSpCas9	negative selection	12475204
30285424	30285447	7	+	28162770	OCIAML3	viability	CTACCTTCCAGTAGCAGCGGAGG	ZNRF2	ENSG00000180233	-0.1439747196891154	[55]	[152]	-1	hSpCas9	negative selection	12475205
30355730	30355753	7	+	28162770	OCIAML3	viability	GATGTACTGAGTAAAGATGCTGG	ZNRF2	ENSG00000180233	1.0795487836659814	[99]	[637]	8	hSpCas9	negative selection	12475206
30285709	30285732	7	+	28162770	OCIAML3	viability	CACAGCAGCCCTGAGGACGGCGG	ZNRF2	ENSG00000180233	-0.6924113443851577	[90]	[169]	-5	hSpCas9	negative selection	12475207
30285434	30285457	7	+	28162770	OCIAML3	viability	GTAGCAGCGGAGGCGCCAATGGG	ZNRF2	ENSG00000180233	1.3457975777570903	[51]	[398]	9	hSpCas9	negative selection	12475208
30285796	30285819	7	-	28162770	OCIAML3	viability	ATGTGCGGCGAGAGGTGAGCTGG	ZNRF2	ENSG00000180233	0.3728254957406376	[32]	[128]	3	hSpCas9	negative selection	12475209
30285811	30285834	7	-	28162770	OCIAML3	viability	TCCGTACCTCCAAACATGTGCGG	ZNRF2	ENSG00000180233	0.4387079348192151	[108]	[445]	4	hSpCas9	negative selection	12475210
30285505	30285528	7	-	28162770	OCIAML3	viability	TGCGCGCTGGGCACCTGAGCCGG	ZNRF2	ENSG00000180233	1.2783445365798767	[30]	[226]	9	hSpCas9	negative selection	12475211