Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 148066
• Symbol: ZNRF4
• Description: zinc and ring finger 4

DataSource: http://genomecrispr.dkfz.de/#!/results/ZNRF4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
5455657	5455680	19	-	26472758	Jiyoye	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	2.6398361382961486	[9]	[46]	9	hSpCas9	negative selection	190629
5455591	5455614	19	-	26472758	Jiyoye	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	-1.7721483179386888	[76]	[16]	-8	hSpCas9	negative selection	190630
5455673	5455696	19	+	26472758	Jiyoye	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	-0.4826417007437037	[62]	[33]	-3	hSpCas9	negative selection	190631
5455961	5455984	19	-	26472758	Jiyoye	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	0.932266426249631	[40]	[58]	6	hSpCas9	negative selection	190632
5455974	5455997	19	-	26472758	Jiyoye	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	-0.6386283081072515	[63]	[30]	-4	hSpCas9	negative selection	190633
5456039	5456062	19	-	26472758	Jiyoye	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	-0.8206305360169389	[88]	[37]	-5	hSpCas9	negative selection	190634
5456114	5456137	19	-	26472758	Jiyoye	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	-0.28189552255602135	[157]	[97]	-2	hSpCas9	negative selection	190635
5456141	5456164	19	-	26472758	Jiyoye	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	-0.6174866727283956	[58]	[28]	-4	hSpCas9	negative selection	190636
5456186	5456209	19	-	26472758	Jiyoye	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	1.928712502085396	[30]	[88]	8	hSpCas9	negative selection	190637
5456651	5456674	19	+	26472758	Jiyoye	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	-0.6057636742016247	[223]	[110]	-4	hSpCas9	negative selection	190638
5455657	5455680	19	-	26472758	KBM7	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	0.36983274228378116	[413,274]	[101,298]	4	hSpCas9	negative selection	381747
5455591	5455614	19	-	26472758	KBM7	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	-0.3761092735224214	[161,99]	[7,80]	-3	hSpCas9	negative selection	381748
5455673	5455696	19	+	26472758	KBM7	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	1.309270764630599	[165,179]	[346,74]	9	hSpCas9	negative selection	381749
5455961	5455984	19	-	26472758	KBM7	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	0.9110006733555163	[380,219]	[274,245]	8	hSpCas9	negative selection	381750
5455974	5455997	19	-	26472758	KBM7	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	0.15719744805202773	[254,137]	[92,106]	1	hSpCas9	negative selection	381751
5456039	5456062	19	-	26472758	KBM7	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	1.394300400702084	[210,156]	[241,209]	9	hSpCas9	negative selection	381752
5456114	5456137	19	-	26472758	KBM7	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	0.8743724495342032	[482,374]	[341,388]	8	hSpCas9	negative selection	381753
5456141	5456164	19	-	26472758	KBM7	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	0.5232543374481003	[219,142]	[118,121]	5	hSpCas9	negative selection	381754
5456186	5456209	19	-	26472758	KBM7	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	-2.2988078220587704	[222,167]	[8,26]	-9	hSpCas9	negative selection	381755
5456651	5456674	19	+	26472758	KBM7	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	0.21033698028497738	[649,521]	[273,354]	2	hSpCas9	negative selection	381756
5455657	5455680	19	-	26472758	Raji	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	-0.2638722718773312	[118]	[22]	-2	hSpCas9	negative selection	572865
5455591	5455614	19	-	26472758	Raji	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	-0.5141048413726705	[79]	[12]	-4	hSpCas9	negative selection	572866
5455673	5455696	19	+	26472758	Raji	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	0.8007221971395477	[93]	[37]	7	hSpCas9	negative selection	572867
5455961	5455984	19	-	26472758	Raji	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	0.6183454546509789	[159]	[56]	6	hSpCas9	negative selection	572868
5455974	5455997	19	-	26472758	Raji	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	-0.7593499337629365	[123]	[16]	-5	hSpCas9	negative selection	572869
5456039	5456062	19	-	26472758	Raji	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	0.10738353537359946	[63]	[15]	1	hSpCas9	negative selection	572870
5456114	5456137	19	-	26472758	Raji	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	-0.7616104524763905	[262]	[35]	-5	hSpCas9	negative selection	572871
5456141	5456164	19	-	26472758	Raji	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	-0.6259708052402279	[132]	[19]	-5	hSpCas9	negative selection	572872
5456186	5456209	19	-	26472758	Raji	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	-3.7752595139882423	[58]	[0]	-9	hSpCas9	negative selection	572873
5456651	5456674	19	+	26472758	Raji	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	0.16501035295565486	[318]	[82]	1	hSpCas9	negative selection	572874
5455657	5455680	19	-	26472758	K562	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	-1.5351912039082527	[205]	[59]	-6	hSpCas9	negative selection	763983
5455591	5455614	19	-	26472758	K562	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	1.181834190288424	[105]	[202]	8	hSpCas9	negative selection	763984
5455673	5455696	19	+	26472758	K562	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	0.8526510077104503	[163]	[249]	7	hSpCas9	negative selection	763985
5455961	5455984	19	-	26472758	K562	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	1.2260869048941898	[197]	[390]	9	hSpCas9	negative selection	763986
5455974	5455997	19	-	26472758	K562	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	0.595493168213326	[195]	[249]	5	hSpCas9	negative selection	763987
5456039	5456062	19	-	26472758	K562	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	0.6594562269452908	[113]	[151]	5	hSpCas9	negative selection	763988
5456114	5456137	19	-	26472758	K562	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	-0.03937423833414429	[363]	[298]	0	hSpCas9	negative selection	763989
5456141	5456164	19	-	26472758	K562	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	0.2444187276664469	[139]	[139]	1	hSpCas9	negative selection	763990
5456186	5456209	19	-	26472758	K562	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	0.9089983964509714	[93]	[148]	7	hSpCas9	negative selection	763991
5456651	5456674	19	+	26472758	K562	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	0.21104259046140444	[480]	[469]	1	hSpCas9	negative selection	763992
5455683	5455706	19	+	26627737	DLD1	viability	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-0.1438786679799653	[255]	[98,55,62]	-1	hSpCas9	negative selection	806673
5456024	5456047	19	-	26627737	DLD1	viability	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.19268336956166027	[339]	[156,172,47]	2	hSpCas9	negative selection	806674
5456082	5456105	19	-	26627737	DLD1	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.2489674728731437	[1183]	[543,588,225]	2	hSpCas9	negative selection	806675
5456279	5456302	19	-	26627737	DLD1	viability	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	0.02753734558365689	[339]	[92,160,77]	0	hSpCas9	negative selection	806678
5456535	5456558	19	-	26627737	DLD1	viability	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.12034659484626653	[3907]	[1504,1215,1266]	1	hSpCas9	negative selection	806679
5456636	5456659	19	-	26627737	DLD1	viability	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.22387678222375806	[284]	[121,100,90]	2	hSpCas9	negative selection	806680
5455683	5455706	19	+	26627737	GBM cells	viability after 5 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-0.6993454484489283	[108]	[39,31]	-8	hSpCas9	negative selection	888988
5456024	5456047	19	-	26627737	GBM cells	viability after 5 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.1482733438224027	[264]	[171,142]	2	hSpCas9	negative selection	888989
5456082	5456105	19	-	26627737	GBM cells	viability after 5 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.032655906288784564	[802]	[430,449]	0	hSpCas9	negative selection	888990
5456279	5456302	19	-	26627737	GBM cells	viability after 5 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-0.030235798643857614	[297]	[175,136]	0	hSpCas9	negative selection	888993
5456535	5456558	19	-	26627737	GBM cells	viability after 5 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	-0.020056773701238484	[1678]	[812,962]	0	hSpCas9	negative selection	888994
5456636	5456659	19	-	26627737	GBM cells	viability after 5 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.5744789243877484	[143]	[116,112]	8	hSpCas9	negative selection	888995
5455683	5455706	19	+	26627737	GBM cells	viability after 13 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-0.9267610720924679	[108]	[45,18]	-8	hSpCas9	negative selection	971303
5456024	5456047	19	-	26627737	GBM cells	viability after 13 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.3850366690998922	[264]	[200,176]	5	hSpCas9	negative selection	971304
5456082	5456105	19	-	26627737	GBM cells	viability after 13 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.048606949244365705	[802]	[518,394]	0	hSpCas9	negative selection	971305
5456279	5456302	19	-	26627737	GBM cells	viability after 13 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-0.6836934119887914	[297]	[114,88]	-7	hSpCas9	negative selection	971308
5456535	5456558	19	-	26627737	GBM cells	viability after 13 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.19423279921670034	[1678]	[1108,987]	2	hSpCas9	negative selection	971309
5456636	5456659	19	-	26627737	GBM cells	viability after 13 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.3049649057103758	[143]	[106,87]	4	hSpCas9	negative selection	971310
5455683	5455706	19	+	26627737	GBM cells	viability after 21 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-1.0760233733138396	[108]	[25,29]	-7	hSpCas9	negative selection	1053618
5456024	5456047	19	-	26627737	GBM cells	viability after 21 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.21447294233297595	[264]	[165,167]	2	hSpCas9	negative selection	1053619
5456082	5456105	19	-	26627737	GBM cells	viability after 21 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.1718807521076775	[802]	[392,381]	-1	hSpCas9	negative selection	1053620
5456279	5456302	19	-	26627737	GBM cells	viability after 21 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-1.150868438657758	[297]	[74,70]	-7	hSpCas9	negative selection	1053623
5456535	5456558	19	-	26627737	GBM cells	viability after 21 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	-0.22890888144550336	[1678]	[793,763]	-2	hSpCas9	negative selection	1053624
5456636	5456659	19	-	26627737	GBM cells	viability after 21 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.31220286462933994	[143]	[93,99]	3	hSpCas9	negative selection	1053625
5455683	5455706	19	+	26627737	RPE1	viability after 9 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-0.17646126708939125	[307]	[28,157]	-1	hSpCas9	negative selection	1135933
5456024	5456047	19	-	26627737	RPE1	viability after 9 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	1.5241314605214913	[373]	[465,169]	8	hSpCas9	negative selection	1135934
5456082	5456105	19	-	26627737	RPE1	viability after 9 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.1052106110990565	[3073]	[988,772]	0	hSpCas9	negative selection	1135935
5456279	5456302	19	-	26627737	RPE1	viability after 9 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	1.2194168945125965	[392]	[189,410]	7	hSpCas9	negative selection	1135938
5456535	5456558	19	-	26627737	RPE1	viability after 9 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	-0.7711903859680564	[5687]	[959,1150]	-5	hSpCas9	negative selection	1135939
5456636	5456659	19	-	26627737	RPE1	viability after 9 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	1.1479550771622185	[466]	[285,372]	7	hSpCas9	negative selection	1135940
5455683	5455706	19	+	26627737	RPE1	viability after 12 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-1.1769033856250832	[307]	[22,50]	-7	hSpCas9	negative selection	1218248
5456024	5456047	19	-	26627737	RPE1	viability after 12 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	1.10563030817993	[373]	[376,45]	6	hSpCas9	negative selection	1218249
5456082	5456105	19	-	26627737	RPE1	viability after 12 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.10652774326127057	[3073]	[945,828]	0	hSpCas9	negative selection	1218250
5456279	5456302	19	-	26627737	RPE1	viability after 12 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	1.2395476508460648	[392]	[259,237]	7	hSpCas9	negative selection	1218253
5456535	5456558	19	-	26627737	RPE1	viability after 12 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	-0.6401154225043362	[5687]	[863,1103]	-4	hSpCas9	negative selection	1218254
5456636	5456659	19	-	26627737	RPE1	viability after 12 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.8916028478711481	[466]	[275,186]	5	hSpCas9	negative selection	1218255
5455683	5455706	19	+	26627737	RPE1	viability after 15 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-1.1139991534909308	[307]	[25,53]	-6	hSpCas9	negative selection	1300563
5456024	5456047	19	-	26627737	RPE1	viability after 15 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.8110268960589169	[373]	[150,218]	5	hSpCas9	negative selection	1300564
5456082	5456105	19	-	26627737	RPE1	viability after 15 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.4210472694706964	[3073]	[538,755]	-3	hSpCas9	negative selection	1300565
5456279	5456302	19	-	26627737	RPE1	viability after 15 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	1.2406059418397983	[392]	[307,218]	7	hSpCas9	negative selection	1300568
5456535	5456558	19	-	26627737	RPE1	viability after 15 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	-0.5987158938781625	[5687]	[893,1224]	-4	hSpCas9	negative selection	1300569
5456636	5456659	19	-	26627737	RPE1	viability after 15 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.4881434061865342	[466]	[224,146]	3	hSpCas9	negative selection	1300570
5455683	5455706	19	+	26627737	RPE1	viability after 18 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	0.14941340693735383	[307]	[53,132]	1	hSpCas9	negative selection	1382878
5456024	5456047	19	-	26627737	RPE1	viability after 18 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.5719115349008574	[373]	[150,148]	3	hSpCas9	negative selection	1382879
5456082	5456105	19	-	26627737	RPE1	viability after 18 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.06862268285984907	[3073]	[825,916]	0	hSpCas9	negative selection	1382880
5456279	5456302	19	-	26627737	RPE1	viability after 18 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	1.100359174677706	[392]	[136,323]	6	hSpCas9	negative selection	1382883
5456535	5456558	19	-	26627737	RPE1	viability after 18 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	-0.9431500819688374	[5687]	[764,833]	-5	hSpCas9	negative selection	1382884
5456636	5456659	19	-	26627737	RPE1	viability after 18 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.9326947804123636	[466]	[329,144]	5	hSpCas9	negative selection	1382885
5455683	5455706	19	+	26627737	HeLa	viability after 8 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	1.5489039705703882	[78]	[51,196,45]	9	hSpCas9	negative selection	1465193
5456024	5456047	19	-	26627737	HeLa	viability after 8 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.3428138413569433	[377]	[314,77,252]	3	hSpCas9	negative selection	1465194
5456082	5456105	19	-	26627737	HeLa	viability after 8 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.1236557256263795	[1195]	[692,362,427]	-1	hSpCas9	negative selection	1465195
5456279	5456302	19	-	26627737	HeLa	viability after 8 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	0.48409347905662903	[223]	[140,161,108]	4	hSpCas9	negative selection	1465198
5456535	5456558	19	-	26627737	HeLa	viability after 8 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.031951974752690404	[2619]	[1057,1544,889]	0	hSpCas9	negative selection	1465199
5456636	5456659	19	-	26627737	HeLa	viability after 8 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	-0.004826666624879072	[258]	[78,39,203]	0	hSpCas9	negative selection	1465200
5455683	5455706	19	+	26627737	HeLa	viability after 12 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	0.5155169133048594	[78]	[0,71,62]	4	hSpCas9	negative selection	1547508
5456024	5456047	19	-	26627737	HeLa	viability after 12 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.5114540281241152	[377]	[227,233,204]	4	hSpCas9	negative selection	1547509
5456082	5456105	19	-	26627737	HeLa	viability after 12 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.41408558270648754	[1195]	[494,903,545]	3	hSpCas9	negative selection	1547510
5456279	5456302	19	-	26627737	HeLa	viability after 12 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	0.5971768946354002	[223]	[217,86,122]	5	hSpCas9	negative selection	1547513
5456535	5456558	19	-	26627737	HeLa	viability after 12 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	-0.017666780930064796	[2619]	[1146,1210,837]	0	hSpCas9	negative selection	1547514
5456636	5456659	19	-	26627737	HeLa	viability after 12 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.48797200829400167	[258]	[161,99,193]	4	hSpCas9	negative selection	1547515
5455683	5455706	19	+	26627737	HeLa	viability after 15 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	1.1635782830582306	[78]	[1,70,149]	7	hSpCas9	negative selection	1629823
5456024	5456047	19	-	26627737	HeLa	viability after 15 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.5477905120923274	[377]	[395,107,163]	4	hSpCas9	negative selection	1629824
5456082	5456105	19	-	26627737	HeLa	viability after 15 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.80645891739933	[1195]	[683,1247,605]	6	hSpCas9	negative selection	1629825
5456279	5456302	19	-	26627737	HeLa	viability after 15 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	0.9133877674463453	[223]	[206,169,134]	7	hSpCas9	negative selection	1629828
5456535	5456558	19	-	26627737	HeLa	viability after 15 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	-0.04925985122207388	[2619]	[640,947,1547]	0	hSpCas9	negative selection	1629829
5456636	5456659	19	-	26627737	HeLa	viability after 15 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.4016782228886191	[258]	[133,155,126]	3	hSpCas9	negative selection	1629830
5455683	5455706	19	+	26627737	HeLa	viability after 18 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	1.1555902870743218	[78]	[1,56,149]	7	hSpCas9	negative selection	1712138
5456024	5456047	19	-	26627737	HeLa	viability after 18 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.5594653197143776	[377]	[263,95,163]	4	hSpCas9	negative selection	1712139
5456082	5456105	19	-	26627737	HeLa	viability after 18 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.8114649243593752	[1195]	[468,1027,605]	6	hSpCas9	negative selection	1712140
5456279	5456302	19	-	26627737	HeLa	viability after 18 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	0.9377867703429106	[223]	[145,138,134]	7	hSpCas9	negative selection	1712143
5456535	5456558	19	-	26627737	HeLa	viability after 18 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	-0.06653411813812493	[2619]	[406,783,1547]	0	hSpCas9	negative selection	1712144
5456636	5456659	19	-	26627737	HeLa	viability after 18 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.40036103990778643	[258]	[88,129,126]	3	hSpCas9	negative selection	1712145
5455683	5455706	19	+	26627737	HCT116	viability after 6 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-0.9991586148434406	[362]	[63,8]	-5	hSpCas9	negative selection	1794453
5456024	5456047	19	-	26627737	HCT116	viability after 6 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	-1.464112405664958	[955]	[145,3]	-7	hSpCas9	negative selection	1794454
5456082	5456105	19	-	26627737	HCT116	viability after 6 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	1.8770422526307273	[968]	[1245,180]	8	hSpCas9	negative selection	1794455
5456279	5456302	19	-	26627737	HCT116	viability after 6 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-0.21475218684514283	[541]	[75,71]	-1	hSpCas9	negative selection	1794458
5456535	5456558	19	-	26627737	HCT116	viability after 6 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	1.9997080618735166	[3683]	[2698,2104]	8	hSpCas9	negative selection	1794459
5456636	5456659	19	-	26627737	HCT116	viability after 6 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.1976160516705612	[471]	[184,29]	1	hSpCas9	negative selection	1794460
5455683	5455706	19	+	26627737	HCT116	viability after 8 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-0.43971217262029705	[146]	[54,57,65]	-5	hSpCas9	negative selection	1876768
5456024	5456047	19	-	26627737	HCT116	viability after 8 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	-0.4078964350002716	[347]	[114,167,149]	-5	hSpCas9	negative selection	1876769
5456082	5456105	19	-	26627737	HCT116	viability after 8 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.3146459602491516	[857]	[599,475,686]	3	hSpCas9	negative selection	1876770
5456279	5456302	19	-	26627737	HCT116	viability after 8 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-0.029385144718460182	[271]	[172,117,149]	0	hSpCas9	negative selection	1876773
5456535	5456558	19	-	26627737	HCT116	viability after 8 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	-0.49088172566113153	[2040]	[805,962,633]	-5	hSpCas9	negative selection	1876774
5456636	5456659	19	-	26627737	HCT116	viability after 8 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	-0.30385949549679314	[335]	[132,195,120]	-4	hSpCas9	negative selection	1876775
5455683	5455706	19	+	26627737	HCT116	viability after 9 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-0.6106630334974243	[362]	[139,2]	-4	hSpCas9	negative selection	1959083
5456024	5456047	19	-	26627737	HCT116	viability after 9 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	-1.0167415165488816	[955]	[157,100]	-6	hSpCas9	negative selection	1959084
5456082	5456105	19	-	26627737	HCT116	viability after 9 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	1.68177672463588	[968]	[1224,517]	8	hSpCas9	negative selection	1959085
5456279	5456302	19	-	26627737	HCT116	viability after 9 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	0.5278971162110592	[541]	[311,126]	4	hSpCas9	negative selection	1959088
5456535	5456558	19	-	26627737	HCT116	viability after 9 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.792802254005716	[3683]	[2102,1388]	5	hSpCas9	negative selection	1959089
5456636	5456659	19	-	26627737	HCT116	viability after 9 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	-0.1489878097053562	[471]	[92,129]	-1	hSpCas9	negative selection	1959090
5455683	5455706	19	+	26627737	HCT116	viability after 12 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-0.24905933576775374	[146]	[90,34,65]	-3	hSpCas9	negative selection	2041398
5456024	5456047	19	-	26627737	HCT116	viability after 12 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.012948335543143341	[347]	[199,215,136]	0	hSpCas9	negative selection	2041399
5456082	5456105	19	-	26627737	HCT116	viability after 12 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.20646929881618203	[857]	[538,429,587]	2	hSpCas9	negative selection	2041400
5456279	5456302	19	-	26627737	HCT116	viability after 12 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-0.5555883679381675	[271]	[66,120,106]	-5	hSpCas9	negative selection	2041403
5456535	5456558	19	-	26627737	HCT116	viability after 12 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.1306548274339896	[2040]	[1291,1030,1185]	1	hSpCas9	negative selection	2041404
5456636	5456659	19	-	26627737	HCT116	viability after 12 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	-0.11928744551655177	[335]	[139,175,173]	-1	hSpCas9	negative selection	2041405
5455683	5455706	19	+	26627737	HCT116	viability after 15 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	0.10802517567014558	[146]	[161,61,57]	1	hSpCas9	negative selection	2123713
5456024	5456047	19	-	26627737	HCT116	viability after 15 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.03620284636706678	[347]	[164,327,117]	0	hSpCas9	negative selection	2123714
5456082	5456105	19	-	26627737	HCT116	viability after 15 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.2793489338089119	[857]	[708,536,561]	2	hSpCas9	negative selection	2123715
5456279	5456302	19	-	26627737	HCT116	viability after 15 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-0.07517819872592879	[271]	[127,135,177]	-1	hSpCas9	negative selection	2123718
5456535	5456558	19	-	26627737	HCT116	viability after 15 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	-0.1840946019315579	[2040]	[818,1030,1216]	-2	hSpCas9	negative selection	2123719
5456636	5456659	19	-	26627737	HCT116	viability after 15 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	-0.556275996017688	[335]	[246,131,29]	-5	hSpCas9	negative selection	2123720
5455683	5455706	19	+	26627737	HCT116	viability after 18 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	0.5794845335856513	[146]	[150,109,54]	5	hSpCas9	negative selection	2206028
5456024	5456047	19	-	26627737	HCT116	viability after 18 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	-0.12756166196188115	[347]	[109,214,131]	-1	hSpCas9	negative selection	2206029
5456082	5456105	19	-	26627737	HCT116	viability after 18 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.07198779902798602	[857]	[315,356,518]	0	hSpCas9	negative selection	2206030
5456279	5456302	19	-	26627737	HCT116	viability after 18 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-0.084126486878528	[271]	[107,71,198]	0	hSpCas9	negative selection	2206033
5456535	5456558	19	-	26627737	HCT116	viability after 18 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.4686709490617629	[2040]	[1694,736,1721]	4	hSpCas9	negative selection	2206034
5456636	5456659	19	-	26627737	HCT116	viability after 18 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	-0.4487730099885301	[335]	[136,111,107]	-4	hSpCas9	negative selection	2206035
5455728	5455751	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAGGCTTTGACTGCCACGAGG	ZNRF4	ENSG00000105428	-0.060397891530840964	[1,2]	[1,2]	-1	hSpCas9	positive selection	3035644
5455552	5455575	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCACTGCCTCTGAGCCACGCGG	ZNRF4	ENSG00000105428	-0.4086632241169402	[3,3]	[3,0]	-5	hSpCas9	positive selection	3035645
5455566	5455589	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.11589456447868925	[2,2]	[2,2]	2	hSpCas9	positive selection	3035646
5455503	5455526	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TAGGCATTAAGTGCTCCGGACGG	ZNRF4	ENSG00000105428	0.22085296865964793	[3,3]	[2,3]	5	hSpCas9	positive selection	3035647
5455728	5455751	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAGGCTTTGACTGCCACGAGG	ZNRF4	ENSG00000105428	0.4159872710198733	[1,1]	[4,0]	7	hSpCas9	positive selection	3103502
5455552	5455575	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCACTGCCTCTGAGCCACGCGG	ZNRF4	ENSG00000105428	-0.14889101129656349	[3,3]	[4,0]	-2	hSpCas9	positive selection	3103503
5455566	5455589	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.30546969277665986	[2,2]	[1,2]	5	hSpCas9	positive selection	3103504
5455503	5455526	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TAGGCATTAAGTGCTCCGGACGG	ZNRF4	ENSG00000105428	0.362252004819327	[3,3]	[3,2]	6	hSpCas9	positive selection	3103505
5455566	5455589		-	24336571	A375	resistance to PLX after 7 days	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.1101346705922676	[11,13]	[16,11]	3	hSpCas9	positive selection	3158401
5456203	5456226		-	24336571	A375	resistance to PLX after 7 days	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.07500692086722316	[6,5]	[6,5]	2	hSpCas9	positive selection	3158402
5455566	5455589		-	24336571	A375	resistance to PLX after 14 days	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	-0.5830175653376781	[13,18]	[4,4]	-7	hSpCas9	positive selection	3216194
5456203	5456226		-	24336571	A375	resistance to PLX after 14 days	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.2449294646167135	[6,3]	[2,2]	2	hSpCas9	positive selection	3216195
5455566	5455589		-	24336571	A375	viability after 7 days	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	-0.13003484821295858	[15]	[11,13]	-2	hSpCas9	negative selection	3273987
5456203	5456226		-	24336571	A375	viability after 7 days	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.7186664315167254	[3]	[6,5]	9	hSpCas9	negative selection	3273988
5455566	5455589		-	24336571	A375	viability after 14 days	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.16487625418054522	[15]	[13,18]	2	hSpCas9	negative selection	3331780
5456203	5456226		-	24336571	A375	viability after 14 days	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.4594096335891944	[3]	[6,3]	6	hSpCas9	negative selection	3331781
5456082	5456105	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.7705797851240493	[260,260]	[0,0]	-5	hSpCas9	positive selection	3403767
5455582	5455605	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	-0.16052630344006283	[170,170]	[0,0]	-1	hSpCas9	positive selection	3403768
5456393	5456416	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.7084580732162519	[249,249]	[0,0]	-5	hSpCas9	positive selection	3403769
5455728	5455751	19	-	26780180	HT29	viability (Avana library 4 designs)	GCAAGGCTTTGACTGCCACGAGG	ZNRF4	ENSG00000105428	1.52235577226243	[]	[]	6	hSpCas9	negative selection	3475002
5455551	5455574	19	+	26780180	HT29	viability (Avana library 4 designs)	GTCACTGCCTCTGAGCCACGCGG	ZNRF4	ENSG00000105428	1.54424095036268	[]	[]	6	hSpCas9	negative selection	3475003
5455566	5455589	19	-	26780180	HT29	viability (Avana library 4 designs)	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.291791121452996	[]	[]	1	hSpCas9	negative selection	3475004
5455503	5455526	19	-	26780180	HT29	viability (Avana library 4 designs)	TAGGCATTAAGTGCTCCGGACGG	ZNRF4	ENSG00000105428	1.35199655841369	[]	[]	5	hSpCas9	negative selection	3475005
5455503	5455526	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	TAGGCATTAAGTGCTCCGGACGG	ZNRF4	ENSG00000105428	-1.55963586834528	[]	[]	-2	hSpCas9	negative selection	3583567
5455566	5455589	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	3.85527315737534	[]	[]	6	hSpCas9	negative selection	3583568
5455728	5455751	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAGGCTTTGACTGCCACGAGG	ZNRF4	ENSG00000105428	8.36298083664103	[]	[]	9	hSpCas9	negative selection	3583569
5455551	5455574	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTCACTGCCTCTGAGCCACGCGG	ZNRF4	ENSG00000105428	5.16576916798634	[]	[]	8	hSpCas9	negative selection	3583570
5455857	5455880	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTATGCCCTCGGGGGCCAGGGGG	ZNRF4	ENSG00000105428	4.24392888712282	[]	[]	7	hSpCas9	negative selection	3583571
5456118	5456141	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	-1.90887015939357	[]	[]	-2	hSpCas9	negative selection	3583572
5455503	5455526	19	-	26780180	A375	viability (Avana lentiGuide)	TAGGCATTAAGTGCTCCGGACGG	ZNRF4	ENSG00000105428	3.50405196807181	[]	[]	3	hSpCas9	negative selection	3692226
5455566	5455589	19	-	26780180	A375	viability (Avana lentiGuide)	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.189886007822392	[]	[]	0	hSpCas9	negative selection	3692227
5455728	5455751	19	-	26780180	A375	viability (Avana lentiGuide)	GCAAGGCTTTGACTGCCACGAGG	ZNRF4	ENSG00000105428	-5.04268025698229	[]	[]	-8	hSpCas9	negative selection	3692228
5455551	5455574	19	+	26780180	A375	viability (Avana lentiGuide)	GTCACTGCCTCTGAGCCACGCGG	ZNRF4	ENSG00000105428	6.82402168601541	[]	[]	5	hSpCas9	negative selection	3692229
5455857	5455880	19	-	26780180	A375	viability (Avana lentiGuide)	GTATGCCCTCGGGGGCCAGGGGG	ZNRF4	ENSG00000105428	2.48837247858347	[]	[]	2	hSpCas9	negative selection	3692230
5456118	5456141	19	-	26780180	A375	viability (Avana lentiGuide)	CCTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	-0.197514397225756	[]	[]	0	hSpCas9	negative selection	3692231
5455503	5455526	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAGGCATTAAGTGCTCCGGACGG	ZNRF4	ENSG00000105428	-0.10992482670940774	[5]	[4,4]	-2	hSpCas9	positive selection	3800833
5455566	5455589	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.1722001126248554	[4]	[5,4]	5	hSpCas9	positive selection	3800834
5455728	5455751	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAGGCTTTGACTGCCACGAGG	ZNRF4	ENSG00000105428	0.5107388500768937	[3]	[5,4]	9	hSpCas9	positive selection	3800835
5455551	5455574	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCACTGCCTCTGAGCCACGCGG	ZNRF4	ENSG00000105428	0.38655492923513024	[4]	[5,7]	9	hSpCas9	positive selection	3800836
5455857	5455880	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTATGCCCTCGGGGGCCAGGGGG	ZNRF4	ENSG00000105428	0.317919247771954	[4]	[5,5]	8	hSpCas9	positive selection	3800837
5456118	5456141	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	-0.28268615550873905	[4]	[4,2]	-4	hSpCas9	positive selection	3800838
5455503	5455526	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAGGCATTAAGTGCTCCGGACGG	ZNRF4	ENSG00000105428	-0.04253683740390138	[5]	[3,4]	0	hSpCas9	positive selection	3909440
5455566	5455589	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	-0.5858827078070252	[4]	[2,1]	-6	hSpCas9	positive selection	3909441
5455728	5455751	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAGGCTTTGACTGCCACGAGG	ZNRF4	ENSG00000105428	-0.3793395977389991	[3]	[0,4]	-5	hSpCas9	positive selection	3909442
5455551	5455574	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCACTGCCTCTGAGCCACGCGG	ZNRF4	ENSG00000105428	0.07175301598581356	[5]	[4,4]	1	hSpCas9	positive selection	3909443
5455857	5455880	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTATGCCCTCGGGGGCCAGGGGG	ZNRF4	ENSG00000105428	0.09120944809696035	[5]	[5,3]	2	hSpCas9	positive selection	3909444
5456118	5456141	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	0.20337494690867722	[4]	[4,4]	5	hSpCas9	positive selection	3909445
5455582	5455605	19	+	26780180	A375	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	1.84201913218782	[]	[]	9	hSpCas9	negative selection	4017393
5455908	5455931	19	+	26780180	A375	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.341902547005768	[]	[]	0	hSpCas9	negative selection	4017394
5456393	5456416	19	-	26780180	A375	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	1.37007127842481	[]	[]	7	hSpCas9	negative selection	4017395
5456082	5456105	19	-	26780180	A375	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	1.45977204341489	[]	[]	8	hSpCas9	negative selection	4017396
5455566	5455589	19	-	26780180	A375	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.673469075828514	[]	[]	2	hSpCas9	negative selection	4017397
5456203	5456226	19	-	26780180	A375	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.520528333819554	[]	[]	1	hSpCas9	negative selection	4017398
5455582	5455605	19	+	26780180	HT29	viability (GeCKOv2 library)	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	1.90403460518471	[]	[]	9	hSpCas9	negative selection	4125359
5455908	5455931	19	+	26780180	HT29	viability (GeCKOv2 library)	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.52429716973465	[]	[]	1	hSpCas9	negative selection	4125360
5456393	5456416	19	-	26780180	HT29	viability (GeCKOv2 library)	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	1.43310156513241	[]	[]	7	hSpCas9	negative selection	4125361
5456082	5456105	19	-	26780180	HT29	viability (GeCKOv2 library)	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	1.66537779105486	[]	[]	8	hSpCas9	negative selection	4125362
5455566	5455589	19	-	26780180	HT29	viability (GeCKOv2 library)	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.658876380012843	[]	[]	2	hSpCas9	negative selection	4125363
5456203	5456226	19	-	26780180	HT29	viability (GeCKOv2 library)	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	1.13369370040075	[]	[]	5	hSpCas9	negative selection	4125364
5455566	5455589	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.03803760680639999	[4]	[3,2]	1	hSpCas9	positive selection	4185664
5456203	5456226	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	-0.25805467104760726	[2]	[0,1]	-6	hSpCas9	positive selection	4185665
5455566	5455589	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.06339435508442026	[4]	[3,1,2,0]	0	hSpCas9	positive selection	4249686
5456203	5456226	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	1.4502540734629585	[0]	[0,0,4,0]	9	hSpCas9	positive selection	4249687
5455566	5455589	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.3266872831833476	[3]	[3,3]	6	hSpCas9	positive selection	4310561
5456203	5456226	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	-0.15091857350317117	[1]	[1,0]	-3	hSpCas9	positive selection	4310562
5455908	5455931	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.1128963335518196	[3]	[4,2]	2	hSpCas9	positive selection	4310563
5456082	5456105	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.48494010305366697	[3]	[3,4]	8	hSpCas9	positive selection	4374808
5455582	5455605	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	-0.6357686561752758	[2]	[1,0]	-9	hSpCas9	positive selection	4374809
5456393	5456416	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.058783663733800784	[3]	[3,2]	1	hSpCas9	positive selection	4374810
5455865	5455887	19	-	27760321	OCIAML3	viability	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	0.24001829283868714	[914,818]	[669,968]	3	hSpCas9	negative selection	4458170
5455909	5455931	19	+	27760321	OCIAML3	viability	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.16963951958052015	[957,780]	[648,906]	2	hSpCas9	negative selection	4458171
5455931	5455953	19	-	27760321	OCIAML3	viability	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	-0.11934659581434914	[1087,947]	[623,870]	-1	hSpCas9	negative selection	4458172
5456067	5456089	19	-	27760321	OCIAML3	viability	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	0.2954395674449768	[720,625]	[613,684]	3	hSpCas9	negative selection	4458173
5456118	5456140	19	-	27760321	OCIAML3	viability	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	-0.1981597127309025	[502,428]	[343,280]	-2	hSpCas9	negative selection	4458174
5455865	5455887	19	-	27760321	OCIAML2	viability	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	0.03797552312146757	[914,818]	[631,833]	0	hSpCas9	negative selection	4541633
5455909	5455931	19	+	27760321	OCIAML2	viability	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.3584114019223089	[957,780]	[765,1069]	5	hSpCas9	negative selection	4541634
5455931	5455953	19	-	27760321	OCIAML2	viability	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	0.2584853314429061	[1087,947]	[804,1216]	3	hSpCas9	negative selection	4541635
5456067	5456089	19	-	27760321	OCIAML2	viability	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	0.6314168096029037	[720,625]	[733,983]	8	hSpCas9	negative selection	4541636
5456118	5456140	19	-	27760321	OCIAML2	viability	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	-0.4761782460497628	[502,428]	[251,293]	-5	hSpCas9	negative selection	4541637
5455865	5455887	19	-	27760321	MV411	viability	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	-0.07194328451656973	[914,818]	[563,512]	0	hSpCas9	negative selection	4625096
5455909	5455931	19	+	27760321	MV411	viability	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	1.0812528157923262	[957,780]	[1083,1393]	7	hSpCas9	negative selection	4625097
5455931	5455953	19	-	27760321	MV411	viability	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	0.7615112613643986	[1087,947]	[1082,1215]	5	hSpCas9	negative selection	4625098
5456067	5456089	19	-	27760321	MV411	viability	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	1.0871663130768234	[720,625]	[799,1154]	7	hSpCas9	negative selection	4625099
5456118	5456140	19	-	27760321	MV411	viability	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	-0.5270360734432046	[502,428]	[113,360]	-4	hSpCas9	negative selection	4625100
5455865	5455887	19	-	27760321	HL60	viability	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	0.38282117679323147	[914,818]	[931,911]	5	hSpCas9	negative selection	4708559
5455909	5455931	19	+	27760321	HL60	viability	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.2692930411105877	[957,780]	[824,879]	3	hSpCas9	negative selection	4708560
5455931	5455953	19	-	27760321	HL60	viability	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	0.6275846063097237	[1087,947]	[1239,1325]	7	hSpCas9	negative selection	4708561
5456067	5456089	19	-	27760321	HL60	viability	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	0.5625057580669054	[720,625]	[1057,547]	6	hSpCas9	negative selection	4708562
5456118	5456140	19	-	27760321	HL60	viability	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	-0.2539112408560947	[502,428]	[357,275]	-3	hSpCas9	negative selection	4708563
5455865	5455887	19	-	27760321	HT1080	viability	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	0.1445933864830049	[818,638]	[194,458]	0	hSpCas9	negative selection	4792022
5455909	5455931	19	+	27760321	HT1080	viability	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	-0.527754964017286	[780,609]	[132,256]	-2	hSpCas9	negative selection	4792023
5455931	5455953	19	-	27760321	HT1080	viability	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	0.4165134504532175	[947,739]	[369,534]	2	hSpCas9	negative selection	4792024
5456067	5456089	19	-	27760321	HT1080	viability	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	0.03128185277591544	[625,488]	[257,192]	0	hSpCas9	negative selection	4792025
5456118	5456140	19	-	27760321	HT1080	viability	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	1.3185940049543803	[428,334]	[454,296]	7	hSpCas9	negative selection	4792026
5455865	5455887	19	-	27760321	HT29	viability after 7 days	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	0.2644268283443769	[818,638]	[1146,1143,1088]	4	hSpCas9	negative selection	4875485
5455909	5455931	19	+	27760321	HT29	viability after 7 days	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.2465472167397651	[780,609]	[1302,701,1205]	4	hSpCas9	negative selection	4875486
5455931	5455953	19	-	27760321	HT29	viability after 7 days	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	0.1451952311414173	[947,739]	[1456,1230,954]	2	hSpCas9	negative selection	4875487
5456067	5456089	19	-	27760321	HT29	viability after 7 days	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	0.32505182916198905	[625,488]	[656,1126,874]	5	hSpCas9	negative selection	4875488
5456118	5456140	19	-	27760321	HT29	viability after 7 days	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	0.028837176233196038	[428,334]	[410,524,551]	0	hSpCas9	negative selection	4875489
5455865	5455887	19	-	27760321	HT29	viability after 25 days	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	0.06551317253852429	[818,638]	[1094,848,630]	0	hSpCas9	negative selection	4958948
5455909	5455931	19	+	27760321	HT29	viability after 25 days	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.6606457278353033	[780,609]	[1487,1241,995]	7	hSpCas9	negative selection	4958949
5455931	5455953	19	-	27760321	HT29	viability after 25 days	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	0.2713739204579477	[947,739]	[1134,1008,1369]	3	hSpCas9	negative selection	4958950
5456067	5456089	19	-	27760321	HT29	viability after 25 days	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	0.332822456644557	[625,488]	[803,731,877]	3	hSpCas9	negative selection	4958951
5456118	5456140	19	-	27760321	HT29	viability after 25 days	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	-0.03303039150466678	[428,334]	[510,414,338]	0	hSpCas9	negative selection	4958952
5455865	5455887	19	-	27760321	HT29	viability after 22 days	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	0.1610392533580256	[818,638]	[1160,805,852]	1	hSpCas9	negative selection	5042411
5455909	5455931	19	+	27760321	HT29	viability after 22 days	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.3446000584419677	[780,609]	[883,1232,948]	3	hSpCas9	negative selection	5042412
5455931	5455953	19	-	27760321	HT29	viability after 22 days	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	0.5092890270654065	[947,739]	[1081,1555,1537]	5	hSpCas9	negative selection	5042413
5456067	5456089	19	-	27760321	HT29	viability after 22 days	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	0.3951401797763481	[625,488]	[871,730,939]	4	hSpCas9	negative selection	5042414
5456118	5456140	19	-	27760321	HT29	viability after 22 days	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	0.25678141100926943	[428,334]	[711,439,424]	2	hSpCas9	negative selection	5042415
5455865	5455887	19	-	27760321	HT29	viability after 19 days	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	0.15132245057707183	[818,638]	[1083,550,1149]	1	hSpCas9	negative selection	5125874
5455909	5455931	19	+	27760321	HT29	viability after 19 days	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.558415256541082	[780,609]	[1248,1217,1058]	5	hSpCas9	negative selection	5125875
5455931	5455953	19	-	27760321	HT29	viability after 19 days	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	0.5768159874990288	[947,739]	[1264,1380,1645]	6	hSpCas9	negative selection	5125876
5456067	5456089	19	-	27760321	HT29	viability after 19 days	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	0.2113900158607761	[625,488]	[1149,680,437]	2	hSpCas9	negative selection	5125877
5456118	5456140	19	-	27760321	HT29	viability after 19 days	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	0.3189471439275122	[428,334]	[763,333,558]	3	hSpCas9	negative selection	5125878
5455865	5455887	19	-	27760321	HT29	viability after 16 days	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	-0.14857495945007237	[818,638]	[1105,321,824]	-1	hSpCas9	negative selection	5209337
5455909	5455931	19	+	27760321	HT29	viability after 16 days	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.5209206499298975	[780,609]	[1116,1137,1093]	6	hSpCas9	negative selection	5209338
5455931	5455953	19	-	27760321	HT29	viability after 16 days	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	0.3894122502781787	[947,739]	[1165,1532,996]	4	hSpCas9	negative selection	5209339
5456067	5456089	19	-	27760321	HT29	viability after 16 days	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	0.25996989579378316	[625,488]	[929,630,699]	3	hSpCas9	negative selection	5209340
5456118	5456140	19	-	27760321	HT29	viability after 16 days	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	0.05124494308875471	[428,334]	[456,435,436]	0	hSpCas9	negative selection	5209341
5455865	5455887	19	-	27760321	HT29	viability after 13 days	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	0.1139496340410906	[818,638]	[1098,900,754]	1	hSpCas9	negative selection	5292800
5455909	5455931	19	+	27760321	HT29	viability after 13 days	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.3538018455913494	[780,609]	[1085,939,1064]	4	hSpCas9	negative selection	5292801
5455931	5455953	19	-	27760321	HT29	viability after 13 days	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	0.36571854210628585	[947,739]	[1073,1344,1359]	4	hSpCas9	negative selection	5292802
5456067	5456089	19	-	27760321	HT29	viability after 13 days	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	0.2796110106499613	[625,488]	[898,807,655]	3	hSpCas9	negative selection	5292803
5456118	5456140	19	-	27760321	HT29	viability after 13 days	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	0.5821887139731542	[428,334]	[545,872,576]	7	hSpCas9	negative selection	5292804
5455865	5455887	19	-	27760321	HT29	viability after 10 days	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	0.03447478498137957	[818,638]	[1219,774,799]	0	hSpCas9	negative selection	5376263
5455909	5455931	19	+	27760321	HT29	viability after 10 days	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.629047869146454	[780,609]	[1346,1062,1604]	8	hSpCas9	negative selection	5376264
5455931	5455953	19	-	27760321	HT29	viability after 10 days	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	0.3002565004290292	[947,739]	[870,1596,1429]	4	hSpCas9	negative selection	5376265
5456067	5456089	19	-	27760321	HT29	viability after 10 days	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	0.29555850745499757	[625,488]	[625,996,941]	4	hSpCas9	negative selection	5376266
5456118	5456140	19	-	27760321	HT29	viability after 10 days	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	0.38359774369456034	[428,334]	[612,693,562]	5	hSpCas9	negative selection	5376267
5455865	5455887	19	-	27760321	MOLM13	viability	TAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	-0.07488905450318062	[914,818]	[371,541]	0	hSpCas9	negative selection	5459726
5455909	5455931	19	+	27760321	MOLM13	viability	AACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.11828032269424804	[957,780]	[794,303]	0	hSpCas9	negative selection	5459727
5455931	5455953	19	-	27760321	MOLM13	viability	GAGCGGTTGCCCAGTCGCGGGG	ZNRF4	ENSG00000105428	0.09227694774783379	[1087,947]	[538,671]	0	hSpCas9	negative selection	5459728
5456067	5456089	19	-	27760321	MOLM13	viability	GACGTGGGTCATGCTCACGAGG	ZNRF4	ENSG00000105428	0.30831402404645614	[720,625]	[531,415]	2	hSpCas9	negative selection	5459729
5456118	5456140	19	-	27760321	MOLM13	viability	CTCGCTCACGAACACTGAGGGG	ZNRF4	ENSG00000105428	-0.4411709538060553	[502,428]	[259,135]	-3	hSpCas9	negative selection	5459730
5455872	5455895	19	+	27661255	K562	viability	GGGCATACGGGGCTACCTGATGG	ZNRF4	ENSG00000105428	0.007796932479685825	[1244,1222]	[1053,937]	0	dCas9-KRAB	negative selection	5526000
5455657	5455680	19	-	27661255	K562	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	0.2301151201948875	[639,813]	[769,599]	7	dCas9-KRAB	negative selection	5526001
5455865	5455888	19	-	27661255	K562	viability	GTAGCCCCGTATGCCCTCGGGGG	ZNRF4	ENSG00000105428	0.2138984804060226	[527,597]	[561,484]	7	dCas9-KRAB	negative selection	5526002
5455947	5455970	19	-	27661255	K562	viability	GCACGATGGCGCCCAGAGAGCGG	ZNRF4	ENSG00000105428	0.3246004367404045	[159,311]	[248,219]	9	dCas9-KRAB	negative selection	5526003
5455566	5455589	19	-	27260156	BXPC3	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.11078654977514968	[839]	[892,837,995,1090]	2	hSpCas9	negative selection	5583021
5456203	5456226	19	-	27260156	BXPC3	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.5019554146597951	[97]	[102,154,131,199]	9	hSpCas9	negative selection	5583022
5455908	5455931	19	+	27260156	BXPC3	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.2731150231356205	[860]	[882,1077,991,1457]	6	hSpCas9	negative selection	5583023
5456082	5456105	19	-	27260156	BXPC3	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.0774918104192246	[780]	[821,859,873,892]	1	hSpCas9	negative selection	5647268
5455582	5455605	19	+	27260156	BXPC3	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.14229147305475254	[433]	[518,408,546,532]	3	hSpCas9	negative selection	5647269
5456393	5456416	19	-	27260156	BXPC3	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.1029927111970163	[647]	[697,785,639,786]	2	hSpCas9	negative selection	5647270
5455566	5455589	19	-	27260156	A673	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	-0.03479763350016418	[839]	[1005,986,1091,844]	-1	hSpCas9	negative selection	5704272
5456203	5456226	19	-	27260156	A673	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.37791585294934693	[97]	[165,144,164,135]	8	hSpCas9	negative selection	5704273
5455908	5455931	19	+	27260156	A673	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.30433091731895723	[860]	[1526,1127,1166,1317]	7	hSpCas9	negative selection	5704274
5456082	5456105	19	-	27260156	A673	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.07042143760388475	[780]	[987,879,872,837]	-2	hSpCas9	negative selection	5768519
5455582	5455605	19	+	27260156	A673	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.24017089229159344	[433]	[585,547,581,750]	5	hSpCas9	negative selection	5768520
5456393	5456416	19	-	27260156	A673	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.01668997802900174	[647]	[774,887,665,742]	0	hSpCas9	negative selection	5768521
5455566	5455589	19	-	27260156	A375	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.04545194990754098	[839]	[1054,1189,895,938]	0	hSpCas9	negative selection	5825523
5456203	5456226	19	-	27260156	A375	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.1072054212183624	[97]	[93,134,223,49]	1	hSpCas9	negative selection	5825524
5455908	5455931	19	+	27260156	A375	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.2558661091796788	[860]	[1288,1252,1318,972]	4	hSpCas9	negative selection	5825525
5456082	5456105	19	-	27260156	A375	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.3617130314857898	[780]	[839,1409,1286,1176]	5	hSpCas9	negative selection	5889770
5455582	5455605	19	+	27260156	A375	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.4492308603014394	[433]	[853,693,673,560]	6	hSpCas9	negative selection	5889771
5456393	5456416	19	-	27260156	A375	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.03559322247493657	[647]	[782,949,642,618]	0	hSpCas9	negative selection	5889772
5455566	5455589	19	-	27260156	COLO741	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.20181047232355898	[839]	[1330,1261,1123]	4	hSpCas9	negative selection	5946774
5456203	5456226	19	-	27260156	COLO741	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.0023487558123216346	[97]	[190,142,52]	0	hSpCas9	negative selection	5946775
5455908	5455931	19	+	27260156	COLO741	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.2599060471586394	[860]	[1409,1249,1297]	5	hSpCas9	negative selection	5946776
5456082	5456105	19	-	27260156	COLO741	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.02485728285718014	[780]	[1095,853,1093]	0	hSpCas9	negative selection	6011021
5455582	5455605	19	+	27260156	COLO741	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.15617919831037225	[433]	[643,598,611]	3	hSpCas9	negative selection	6011022
5456393	5456416	19	-	27260156	COLO741	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.3366436612329081	[647]	[829,704,459]	-6	hSpCas9	negative selection	6011023
5455566	5455589	19	-	27260156	CAL120	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.43478659382477436	[839]	[1189,2012,1008]	6	hSpCas9	negative selection	6068025
5456203	5456226	19	-	27260156	CAL120	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.47367452371589636	[97]	[231,205,80]	7	hSpCas9	negative selection	6068026
5455908	5455931	19	+	27260156	CAL120	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.7629012434031306	[860]	[2170,1315,2015]	9	hSpCas9	negative selection	6068027
5456082	5456105	19	-	27260156	CAL120	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.2962128819688238	[780]	[1627,878,1138]	4	hSpCas9	negative selection	6132272
5455582	5455605	19	+	27260156	CAL120	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.2444760515179245	[433]	[744,720,471]	3	hSpCas9	negative selection	6132273
5456393	5456416	19	-	27260156	CAL120	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.18639843898061909	[647]	[857,1169,718]	2	hSpCas9	negative selection	6132274
5455566	5455589	19	-	27260156	CADOES1	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	-0.22302356745173701	[839]	[631,571,784,688]	-4	hSpCas9	negative selection	6189276
5456203	5456226	19	-	27260156	CADOES1	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.8512085397452609	[97]	[138,138,156,224]	9	hSpCas9	negative selection	6189277
5455908	5455931	19	+	27260156	CADOES1	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.3116139322757199	[860]	[969,1067,1060,871]	5	hSpCas9	negative selection	6189278
5456082	5456105	19	-	27260156	CADOES1	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.1001106956936767	[780]	[896,683,544,995]	1	hSpCas9	negative selection	6253523
5455582	5455605	19	+	27260156	CADOES1	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.43457641098416644	[433]	[444,656,397,687]	7	hSpCas9	negative selection	6253524
5456393	5456416	19	-	27260156	CADOES1	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.21572379191561317	[647]	[480,533,567,491]	-4	hSpCas9	negative selection	6253525
5455566	5455589	19	-	27260156	EWS502	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.03085723869806889	[839]	[761,926,1058,902]	0	hSpCas9	negative selection	6310527
5456203	5456226	19	-	27260156	EWS502	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.31222571729558934	[97]	[165,98,142,101]	5	hSpCas9	negative selection	6310528
5455908	5455931	19	+	27260156	EWS502	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.3309360589363912	[860]	[960,1243,1234,1164]	6	hSpCas9	negative selection	6310529
5456082	5456105	19	-	27260156	EWS502	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.19495467779710463	[780]	[782,1130,937,943]	3	hSpCas9	negative selection	6374774
5455582	5455605	19	+	27260156	EWS502	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.12291701483457845	[433]	[523,330,529,628]	2	hSpCas9	negative selection	6374775
5456393	5456416	19	-	27260156	EWS502	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.00355190698901775	[647]	[535,707,775,752]	0	hSpCas9	negative selection	6374776
5455566	5455589	19	-	27260156	EW8	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	-0.11988537000349386	[839]	[622,791,553,547]	-2	hSpCas9	negative selection	6431778
5456203	5456226	19	-	27260156	EW8	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.15635420313306314	[97]	[61,103,87,96]	3	hSpCas9	negative selection	6431779
5455908	5455931	19	+	27260156	EW8	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.2025942495022428	[860]	[851,817,599,978]	4	hSpCas9	negative selection	6431780
5456082	5456105	19	-	27260156	EW8	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.275694552728711	[780]	[872,716,701,792]	5	hSpCas9	negative selection	6496025
5455582	5455605	19	+	27260156	EW8	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.6445797495507444	[433]	[518,863,493,328]	9	hSpCas9	negative selection	6496026
5456393	5456416	19	-	27260156	EW8	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.09189720507780325	[647]	[821,449,420,595]	1	hSpCas9	negative selection	6496027
5455566	5455589	19	-	27260156	CORL105	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.1611116008894784	[839]	[1064,846,1346,1180]	3	hSpCas9	negative selection	6553029
5456203	5456226	19	-	27260156	CORL105	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	-0.03104318196560163	[97]	[98,123,115,109]	0	hSpCas9	negative selection	6553030
5455908	5455931	19	+	27260156	CORL105	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.44961667402290395	[860]	[1496,1005,1819,1263]	8	hSpCas9	negative selection	6553031
5456082	5456105	19	-	27260156	CORL105	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.017174483607776403	[780]	[954,959,1110,704]	0	hSpCas9	negative selection	6617276
5455582	5455605	19	+	27260156	CORL105	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.31284949008300056	[433]	[647,429,749,718]	6	hSpCas9	negative selection	6617277
5456393	5456416	19	-	27260156	CORL105	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.10083903034698521	[647]	[793,645,834,578]	-2	hSpCas9	negative selection	6617278
5455566	5455589	19	-	27260156	HS294T	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.08313654156844008	[839]	[229,290,472,403]	1	hSpCas9	negative selection	6674280
5456203	5456226	19	-	27260156	HS294T	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.24167365303735489	[97]	[42,37,55,41]	3	hSpCas9	negative selection	6674281
5455908	5455931	19	+	27260156	HS294T	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.6831834258198233	[860]	[778,338,527,460]	8	hSpCas9	negative selection	6674282
5456082	5456105	19	-	27260156	HS294T	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.14897715647114318	[780]	[315,359,358,297]	2	hSpCas9	negative selection	6738527
5455582	5455605	19	+	27260156	HS294T	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.01896019522730849	[433]	[185,144,176,170]	0	hSpCas9	negative selection	6738528
5456393	5456416	19	-	27260156	HS294T	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.16685655261593446	[647]	[182,151,351,208]	-2	hSpCas9	negative selection	6738529
5455566	5455589	19	-	27260156	HCC44	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.21964653395464828	[839]	[1401,1213,937,852]	3	hSpCas9	negative selection	6795531
5456203	5456226	19	-	27260156	HCC44	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.8842564501658017	[97]	[156,171,327,181]	9	hSpCas9	negative selection	6795532
5455908	5455931	19	+	27260156	HCC44	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.4361152105063206	[860]	[1571,1206,1533,1031]	7	hSpCas9	negative selection	6795533
5456082	5456105	19	-	27260156	HCC44	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.24700444917138142	[780]	[1241,975,1079,923]	4	hSpCas9	negative selection	6859778
5455582	5455605	19	+	27260156	HCC44	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.3544648530115856	[433]	[458,493,1013,608]	6	hSpCas9	negative selection	6859779
5456393	5456416	19	-	27260156	HCC44	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.2857502357146057	[647]	[834,627,940,1192]	4	hSpCas9	negative selection	6859780
5455566	5455589	19	-	27260156	G402	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.09145056915921812	[839]	[1549,823,916,1121]	1	hSpCas9	negative selection	6916782
5456203	5456226	19	-	27260156	G402	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.6514387276013336	[97]	[201,81,94,358]	7	hSpCas9	negative selection	6916783
5455908	5455931	19	+	27260156	G402	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.3566731597821797	[860]	[1908,1354,1001,1198]	4	hSpCas9	negative selection	6916784
5456082	5456105	19	-	27260156	G402	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.5624200970504539	[780]	[1552,1137,1188,1732]	7	hSpCas9	negative selection	6981029
5455582	5455605	19	+	27260156	G402	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.9100718263099113	[433]	[543,765,1800,796]	9	hSpCas9	negative selection	6981030
5456393	5456416	19	-	27260156	G402	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.28120368291029874	[647]	[625,936,691,371]	-4	hSpCas9	negative selection	6981031
5455566	5455589	19	-	27260156	L33	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.0976878824647529	[839]	[892,372,531,944]	2	hSpCas9	negative selection	7038033
5456203	5456226	19	-	27260156	L33	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.45480411361297435	[97]	[128,51,86,142]	8	hSpCas9	negative selection	7038034
5455908	5455931	19	+	27260156	L33	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.472584111811184	[860]	[1113,450,765,1345]	8	hSpCas9	negative selection	7038035
5456082	5456105	19	-	27260156	L33	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.126823171214267	[780]	[788,326,638,809]	3	hSpCas9	negative selection	7102280
5455582	5455605	19	+	27260156	L33	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.2017846847851033	[433]	[412,238,288,541]	4	hSpCas9	negative selection	7102281
5456393	5456416	19	-	27260156	L33	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.23399945363731559	[647]	[512,278,312,512]	-5	hSpCas9	negative selection	7102282
5455566	5455589	19	-	27260156	K562	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	-0.3674718536386371	[839]	[532,478,521,745]	-4	hSpCas9	negative selection	7159284
5456203	5456226	19	-	27260156	K562	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.5628782771346006	[97]	[71,193,153,95]	7	hSpCas9	negative selection	7159285
5455908	5455931	19	+	27260156	K562	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.0851998044008675	[860]	[898,771,922,666]	1	hSpCas9	negative selection	7159286
5456082	5456105	19	-	27260156	K562	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.21510991768052012	[780]	[588,738,584,491]	-3	hSpCas9	negative selection	7223531
5455582	5455605	19	+	27260156	K562	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.6801302560575223	[433]	[672,528,516,732]	8	hSpCas9	negative selection	7223532
5456393	5456416	19	-	27260156	K562	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.06106549682611223	[647]	[749,492,423,548]	0	hSpCas9	negative selection	7223533
5455566	5455589	19	-	27260156	HT29	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.035560915307717544	[839]	[1148,1198,1103,780]	0	hSpCas9	negative selection	7280535
5456203	5456226	19	-	27260156	HT29	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.17828891182476703	[97]	[119,114,206,97]	3	hSpCas9	negative selection	7280536
5455908	5455931	19	+	27260156	HT29	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.46585671146488905	[860]	[1555,1837,1280,1172]	8	hSpCas9	negative selection	7280537
5456082	5456105	19	-	27260156	HT29	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.03262850281976071	[780]	[1068,1165,788,887]	0	hSpCas9	negative selection	7344782
5455582	5455605	19	+	27260156	HT29	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.05147932552716751	[433]	[656,571,546,431]	1	hSpCas9	negative selection	7344783
5456393	5456416	19	-	27260156	HT29	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.08431368004630352	[647]	[863,685,1029,753]	1	hSpCas9	negative selection	7344784
5455566	5455589	19	-	27260156	MHHES1	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.18118807115810664	[839]	[1261,1100,1122,856]	3	hSpCas9	negative selection	7401786
5456203	5456226	19	-	27260156	MHHES1	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.6359987499783253	[97]	[156,152,193,173]	9	hSpCas9	negative selection	7401787
5455908	5455931	19	+	27260156	MHHES1	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.18279331186713255	[860]	[1032,1542,1071,829]	3	hSpCas9	negative selection	7401788
5456082	5456105	19	-	27260156	MHHES1	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.12750777261552382	[780]	[776,1230,1040,812]	2	hSpCas9	negative selection	7466033
5455582	5455605	19	+	27260156	MHHES1	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	-0.13336672398855892	[433]	[472,490,346,463]	-2	hSpCas9	negative selection	7466034
5456393	5456416	19	-	27260156	MHHES1	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.1310391138472668	[647]	[893,673,905,721]	2	hSpCas9	negative selection	7466035
5455566	5455589	19	-	27260156	MEWO	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.1891545320850916	[839]	[1220,829,699]	4	hSpCas9	negative selection	7523037
5456203	5456226	19	-	27260156	MEWO	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.047486509798192245	[97]	[113,87,85]	1	hSpCas9	negative selection	7523038
5455908	5455931	19	+	27260156	MEWO	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.520968923772156	[860]	[1296,1083,1113]	9	hSpCas9	negative selection	7523039
5456082	5456105	19	-	27260156	MEWO	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.006237967616874007	[780]	[984,580,666]	0	hSpCas9	negative selection	7587284
5455582	5455605	19	+	27260156	MEWO	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.1973604942487827	[433]	[493,481,425]	4	hSpCas9	negative selection	7587285
5456393	5456416	19	-	27260156	MEWO	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.09244222128243468	[647]	[558,539,604]	-2	hSpCas9	negative selection	7587286
5455566	5455589	19	-	27260156	LNCAPCLONEFGC	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.18433923656850637	[839]	[935,795,944,795]	3	hSpCas9	negative selection	7644288
5456203	5456226	19	-	27260156	LNCAPCLONEFGC	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.39603081456339506	[97]	[168,98,100,95]	6	hSpCas9	negative selection	7644289
5455908	5455931	19	+	27260156	LNCAPCLONEFGC	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.3262212945828429	[860]	[847,893,1228,984]	5	hSpCas9	negative selection	7644290
5456082	5456105	19	-	27260156	LNCAPCLONEFGC	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.21144034051834193	[780]	[861,757,911,760]	3	hSpCas9	negative selection	7708535
5455582	5455605	19	+	27260156	LNCAPCLONEFGC	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.4418672401281484	[433]	[492,425,771,487]	7	hSpCas9	negative selection	7708536
5456393	5456416	19	-	27260156	LNCAPCLONEFGC	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.18940593810056594	[647]	[435,489,730,436]	-3	hSpCas9	negative selection	7708537
5455566	5455589	19	-	27260156	PANC0327	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.3789433626917156	[839]	[1168,795,1061,892]	5	hSpCas9	negative selection	7765539
5456203	5456226	19	-	27260156	PANC0327	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	1.0891317418689703	[97]	[228,164,196,155]	9	hSpCas9	negative selection	7765540
5455908	5455931	19	+	27260156	PANC0327	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.8404858952653744	[860]	[1984,1249,956,1350]	9	hSpCas9	negative selection	7765541
5456082	5456105	19	-	27260156	PANC0327	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.1234967757126696	[780]	[1034,727,547,737]	1	hSpCas9	negative selection	7829786
5455582	5455605	19	+	27260156	PANC0327	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.30044348281061833	[433]	[604,412,610,288]	4	hSpCas9	negative selection	7829787
5456393	5456416	19	-	27260156	PANC0327	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.04962367371568632	[647]	[797,286,556,636]	0	hSpCas9	negative selection	7829788
5455566	5455589	19	-	27260156	NCIH2009	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.4216594076243505	[839]	[2062,1429,1319]	6	hSpCas9	negative selection	7886790
5456203	5456226	19	-	27260156	NCIH2009	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.8388490034499554	[97]	[373,178,207]	9	hSpCas9	negative selection	7886791
5455908	5455931	19	+	27260156	NCIH2009	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.7564368552577299	[860]	[2466,1755,1960]	9	hSpCas9	negative selection	7886792
5456082	5456105	19	-	27260156	NCIH2009	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.4319837923902369	[780]	[1700,1473,1283]	6	hSpCas9	negative selection	7951037
5455582	5455605	19	+	27260156	NCIH2009	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.25138967874599005	[433]	[922,661,619]	3	hSpCas9	negative selection	7951038
5456393	5456416	19	-	27260156	NCIH2009	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.5086932332649817	[647]	[822,626,494]	-6	hSpCas9	negative selection	7951039
5455566	5455589	19	-	27260156	NCIH1373	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	-0.21545593921455686	[839]	[888,709,844,214]	-2	hSpCas9	negative selection	8008041
5456203	5456226	19	-	27260156	NCIH1373	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.8758092296105389	[97]	[81,157,447,23]	8	hSpCas9	negative selection	8008042
5455908	5455931	19	+	27260156	NCIH1373	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.24968811642843347	[860]	[1198,1325,958,285]	2	hSpCas9	negative selection	8008043
5456082	5456105	19	-	27260156	NCIH1373	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.11760064191919661	[780]	[861,942,630,361]	1	hSpCas9	negative selection	8072288
5455582	5455605	19	+	27260156	NCIH1373	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.4100850361546979	[433]	[786,357,856,164]	4	hSpCas9	negative selection	8072289
5456393	5456416	19	-	27260156	NCIH1373	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.13303629469099826	[647]	[682,1051,682,187]	1	hSpCas9	negative selection	8072290
5455566	5455589	19	-	27260156	PATU8902	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.3139149486415309	[839]	[1123,2025,1360,1306]	3	hSpCas9	negative selection	8129292
5456203	5456226	19	-	27260156	PATU8902	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.3270997401763944	[97]	[357,88,147,80]	3	hSpCas9	negative selection	8129293
5455908	5455931	19	+	27260156	PATU8902	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.40062061100261204	[860]	[1312,1847,1243,2063]	4	hSpCas9	negative selection	8129294
5456082	5456105	19	-	27260156	PATU8902	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.5671423214705155	[780]	[2064,1394,1345,1699]	6	hSpCas9	negative selection	8193539
5455582	5455605	19	+	27260156	PATU8902	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.15045298617783592	[433]	[764,571,457,972]	1	hSpCas9	negative selection	8193540
5456393	5456416	19	-	27260156	PATU8902	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.5004972741021734	[647]	[1497,860,1215,1567]	5	hSpCas9	negative selection	8193541
5455566	5455589	19	-	27260156	PANC1	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.12854629999203804	[839]	[610,1091,819,699]	2	hSpCas9	negative selection	8250543
5456203	5456226	19	-	27260156	PANC1	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	-0.04025752644405678	[97]	[97,97,78,57]	0	hSpCas9	negative selection	8250544
5455908	5455931	19	+	27260156	PANC1	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.2904356635326797	[860]	[864,1198,943,691]	5	hSpCas9	negative selection	8250545
5456082	5456105	19	-	27260156	PANC1	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.0752574382037885	[780]	[691,892,630,646]	1	hSpCas9	negative selection	8314790
5455582	5455605	19	+	27260156	PANC1	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.19877930755619927	[433]	[393,530,500,318]	3	hSpCas9	negative selection	8314791
5456393	5456416	19	-	27260156	PANC1	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.08662702518317028	[647]	[668,632,539,528]	1	hSpCas9	negative selection	8314792
5455566	5455589	19	-	27260156	PANC0813	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	-0.05365406289272123	[839]	[1362,900,919,670]	-1	hSpCas9	negative selection	8371794
5456203	5456226	19	-	27260156	PANC0813	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.3377567886608337	[97]	[151,93,198,137]	5	hSpCas9	negative selection	8371795
5455908	5455931	19	+	27260156	PANC0813	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.5889789444762992	[860]	[1796,1435,1484,1396]	8	hSpCas9	negative selection	8371796
5456082	5456105	19	-	27260156	PANC0813	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.053849752349548585	[780]	[1221,822,971,822]	0	hSpCas9	negative selection	8436041
5455582	5455605	19	+	27260156	PANC0813	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.2872828516779363	[433]	[604,629,458,781]	4	hSpCas9	negative selection	8436042
5456393	5456416	19	-	27260156	PANC0813	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.0025124769796366353	[647]	[1081,726,710,568]	0	hSpCas9	negative selection	8436043
5455566	5455589	19	-	27260156	RDES	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	-0.1425572180149972	[839]	[723,817,981,1012]	-2	hSpCas9	negative selection	8493045
5456203	5456226	19	-	27260156	RDES	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.8574371083617178	[97]	[172,221,162,264]	9	hSpCas9	negative selection	8493046
5455908	5455931	19	+	27260156	RDES	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.3073741975363209	[860]	[955,1065,1323,1663]	5	hSpCas9	negative selection	8493047
5456082	5456105	19	-	27260156	RDES	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.21914628782475087	[780]	[875,1053,1042,1241]	3	hSpCas9	negative selection	8557292
5455582	5455605	19	+	27260156	RDES	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.29588057197731743	[433]	[588,524,620,726]	5	hSpCas9	negative selection	8557293
5456393	5456416	19	-	27260156	RDES	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.03282199941924335	[647]	[535,693,860,1038]	0	hSpCas9	negative selection	8557294
5455566	5455589	19	-	27260156	PC3	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	-0.22787856964533393	[839]	[389,799,1139,772]	-5	hSpCas9	negative selection	8614296
5456203	5456226	19	-	27260156	PC3	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.47977216192346717	[97]	[80,214,129,121]	8	hSpCas9	negative selection	8614297
5455908	5455931	19	+	27260156	PC3	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.3550488482267198	[860]	[642,1130,1583,1327]	7	hSpCas9	negative selection	8614298
5456082	5456105	19	-	27260156	PC3	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.11773385471299636	[780]	[530,854,1655,700]	2	hSpCas9	negative selection	8678543
5455582	5455605	19	+	27260156	PC3	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.06807498745935797	[433]	[241,671,527,439]	1	hSpCas9	negative selection	8678544
5456393	5456416	19	-	27260156	PC3	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.004895617723293499	[647]	[455,531,1304,573]	0	hSpCas9	negative selection	8678545
5455566	5455589	19	-	27260156	PATU8988T	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.053331492329771635	[839]	[1066,806,624,871]	0	hSpCas9	negative selection	8735547
5456203	5456226	19	-	27260156	PATU8988T	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.9855700639664229	[97]	[262,96,168,214]	9	hSpCas9	negative selection	8735548
5455908	5455931	19	+	27260156	PATU8988T	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.04622219703407815	[860]	[725,1160,693,887]	0	hSpCas9	negative selection	8735549
5456082	5456105	19	-	27260156	PATU8988T	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.0672173888147356	[780]	[686,722,691,784]	-1	hSpCas9	negative selection	8799794
5455582	5455605	19	+	27260156	PATU8988T	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.08115383437934903	[433]	[584,392,349,442]	1	hSpCas9	negative selection	8799795
5456393	5456416	19	-	27260156	PATU8988T	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.37472667386386244	[647]	[610,937,1062,628]	6	hSpCas9	negative selection	8799796
5455566	5455589	19	-	27260156	T47D	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.006970069471515239	[839]	[1056,902,916,1066]	0	hSpCas9	negative selection	8856798
5456203	5456226	19	-	27260156	T47D	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.30848912021780595	[97]	[149,101,183,131]	6	hSpCas9	negative selection	8856799
5455908	5455931	19	+	27260156	T47D	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.2652366615105226	[860]	[1310,1135,1227,1150]	5	hSpCas9	negative selection	8856800
5456082	5456105	19	-	27260156	T47D	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.014687863608055074	[780]	[883,888,943,884]	0	hSpCas9	negative selection	8921045
5455582	5455605	19	+	27260156	T47D	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.1097917000096708	[433]	[566,463,556,602]	2	hSpCas9	negative selection	8921046
5456393	5456416	19	-	27260156	T47D	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.013112599220395982	[647]	[840,674,768,769]	0	hSpCas9	negative selection	8921047
5455566	5455589	19	-	27260156	SU8686	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.05842703025743179	[839]	[1055,742,817,832]	1	hSpCas9	negative selection	8978049
5456203	5456226	19	-	27260156	SU8686	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	-0.11051537362211672	[97]	[94,62,95,111]	-2	hSpCas9	negative selection	8978050
5455908	5455931	19	+	27260156	SU8686	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.33785768931073656	[860]	[991,878,1137,1385]	6	hSpCas9	negative selection	8978051
5456082	5456105	19	-	27260156	SU8686	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.07070866125578512	[780]	[768,664,806,1071]	1	hSpCas9	negative selection	9042296
5455582	5455605	19	+	27260156	SU8686	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.18544835266402412	[433]	[506,476,465,504]	3	hSpCas9	negative selection	9042297
5456393	5456416	19	-	27260156	SU8686	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.06805408135622065	[647]	[757,514,569,888]	1	hSpCas9	negative selection	9042298
5455566	5455589	19	-	27260156	SKES1	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.013005796048599083	[839]	[1087,760,813,745]	0	hSpCas9	negative selection	9099300
5456203	5456226	19	-	27260156	SKES1	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.8076491205392236	[97]	[239,177,188,94]	9	hSpCas9	negative selection	9099301
5455908	5455931	19	+	27260156	SKES1	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.17227458419963182	[860]	[936,1355,930,710]	4	hSpCas9	negative selection	9099302
5456082	5456105	19	-	27260156	SKES1	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.12213233327552842	[780]	[629,920,727,602]	-3	hSpCas9	negative selection	9163547
5455582	5455605	19	+	27260156	SKES1	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.09536217976196687	[433]	[557,550,307,454]	2	hSpCas9	negative selection	9163548
5456393	5456416	19	-	27260156	SKES1	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	0.1688650247097207	[647]	[928,811,673,544]	3	hSpCas9	negative selection	9163549
5455566	5455589	19	-	27260156	TOV112D	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	-0.18890689498347724	[839]	[943,700,568,744]	-4	hSpCas9	negative selection	9220551
5456203	5456226	19	-	27260156	TOV112D	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.2779362099539229	[97]	[120,120,97,135]	5	hSpCas9	negative selection	9220552
5455908	5455931	19	+	27260156	TOV112D	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.332112092491881	[860]	[857,1036,918,1483]	6	hSpCas9	negative selection	9220553
5456082	5456105	19	-	27260156	TOV112D	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.4336153272711144	[780]	[1477,1224,864,741]	7	hSpCas9	negative selection	9284798
5455582	5455605	19	+	27260156	TOV112D	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.0983670315123046	[433]	[418,391,429,593]	2	hSpCas9	negative selection	9284799
5456393	5456416	19	-	27260156	TOV112D	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.2010919674997364	[647]	[977,478,427,390]	-4	hSpCas9	negative selection	9284800
5455566	5455589	19	-	27260156	TC71	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.02814130422129668	[839]	[899,901,880,995]	0	hSpCas9	negative selection	9341802
5456203	5456226	19	-	27260156	TC71	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.7251719951330031	[97]	[176,220,135,160]	9	hSpCas9	negative selection	9341803
5455908	5455931	19	+	27260156	TC71	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.20989152786704945	[860]	[971,1069,1088,1144]	5	hSpCas9	negative selection	9341804
5456082	5456105	19	-	27260156	TC71	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.14550024657248528	[780]	[718,872,698,737]	-4	hSpCas9	negative selection	9406049
5455582	5455605	19	+	27260156	TC71	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	-0.015647303585845193	[433]	[468,414,409,553]	0	hSpCas9	negative selection	9406050
5456393	5456416	19	-	27260156	TC71	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.054357913541640324	[647]	[739,627,648,656]	-1	hSpCas9	negative selection	9406051
5455566	5455589	19	-	27260156	TC32	viability	GTTGAGTTGGAATGACCGCGTGG	ZNRF4	ENSG00000105428	0.016907732579985013	[839]	[782,651,1032,773]	0	hSpCas9	negative selection	9463053
5456203	5456226	19	-	27260156	TC32	viability	TCGTGGCACGGTGGGTCGTCGGG	ZNRF4	ENSG00000105428	0.7809480215956521	[97]	[200,129,153,140]	9	hSpCas9	negative selection	9463054
5455908	5455931	19	+	27260156	TC32	viability	CAACGCGTGCCATCCCATCGAGG	ZNRF4	ENSG00000105428	0.21989023843395628	[860]	[853,906,1166,837]	4	hSpCas9	negative selection	9463055
5456082	5456105	19	-	27260156	TC32	viability	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.10858812121935957	[780]	[710,558,1054,946]	2	hSpCas9	negative selection	9527300
5455582	5455605	19	+	27260156	TC32	viability	ACTCAACTGCCCTCGCGTCCTGG	ZNRF4	ENSG00000105428	0.23565021852833062	[433]	[540,218,644,616]	4	hSpCas9	negative selection	9527301
5456393	5456416	19	-	27260156	TC32	viability	CAGGTCGTTGTGCCACGTGAAGG	ZNRF4	ENSG00000105428	-0.029623133798729884	[647]	[650,481,641,618]	0	hSpCas9	negative selection	9527302
5455683	5455706	19	+	27869803	HPAFII	viability after 27 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-0.6116637460396175	[143]	[102,4,NaN]	-4	hSpCas9	negative selection	9569708
5456024	5456047	19	-	27869803	HPAFII	viability after 27 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	-0.8527471653592207	[261]	[114,43,NaN]	-6	hSpCas9	negative selection	9569709
5456082	5456105	19	-	27869803	HPAFII	viability after 27 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.11880771511483745	[723]	[343,355,NaN]	-1	hSpCas9	negative selection	9569710
5456279	5456302	19	-	27869803	HPAFII	viability after 27 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-0.10121680993173143	[229]	[43,169,NaN]	0	hSpCas9	negative selection	9569713
5456535	5456558	19	-	27869803	HPAFII	viability after 27 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.09273942036567195	[1172]	[499,788,NaN]	0	hSpCas9	negative selection	9569714
5456636	5456659	19	-	27869803	HPAFII	viability after 27 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	-0.2354581614813691	[170]	[131,29,NaN]	-2	hSpCas9	negative selection	9569715
5455683	5455706	19	+	27869803	HPAFII	viability after 15 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-1.4404280529464473	[143]	[122,15,NaN]	-8	hSpCas9	negative selection	9652157
5456024	5456047	19	-	27869803	HPAFII	viability after 15 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	-0.7772210263896202	[261]	[323,64,NaN]	-7	hSpCas9	negative selection	9652158
5456082	5456105	19	-	27869803	HPAFII	viability after 15 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.12841618371063035	[723]	[926,802,NaN]	1	hSpCas9	negative selection	9652159
5456279	5456302	19	-	27869803	HPAFII	viability after 15 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-0.7790614878063571	[229]	[119,158,NaN]	-7	hSpCas9	negative selection	9652162
5456535	5456558	19	-	27869803	HPAFII	viability after 15 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.2866378773076681	[1172]	[2170,1143,NaN]	3	hSpCas9	negative selection	9652163
5456636	5456659	19	-	27869803	HPAFII	viability after 15 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.2730941728427446	[170]	[337,149,NaN]	3	hSpCas9	negative selection	9652164
5455683	5455706	19	+	27869803	ASPC1	viability after 36 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	0.08430082102415071	[197]	[4,166,45]	0	hSpCas9	negative selection	9734606
5456024	5456047	19	-	27869803	ASPC1	viability after 36 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.19583838743520915	[544]	[227,273,163]	2	hSpCas9	negative selection	9734607
5456082	5456105	19	-	27869803	ASPC1	viability after 36 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.025502390399300134	[1859]	[742,698,565]	0	hSpCas9	negative selection	9734608
5456279	5456302	19	-	27869803	ASPC1	viability after 36 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	0.08236903664842746	[653]	[213,278,228]	0	hSpCas9	negative selection	9734611
5456535	5456558	19	-	27869803	ASPC1	viability after 36 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.5499830656574853	[3404]	[2695,1562,1191]	5	hSpCas9	negative selection	9734612
5456636	5456659	19	-	27869803	ASPC1	viability after 36 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	0.126985109833193	[312]	[116,162,84]	1	hSpCas9	negative selection	9734613
5455683	5455706	19	+	27869803	PATU8988S	viability after 35 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	0.7056344261935544	[177]	[79,153,NaN]	7	hSpCas9	negative selection	9817055
5456024	5456047	19	-	27869803	PATU8988S	viability after 35 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.43882367296898245	[511]	[285,272,NaN]	5	hSpCas9	negative selection	9817056
5456082	5456105	19	-	27869803	PATU8988S	viability after 35 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.4375220139648004	[1452]	[799,784,NaN]	5	hSpCas9	negative selection	9817057
5456279	5456302	19	-	27869803	PATU8988S	viability after 35 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	0.11230545224217986	[372]	[112,211,NaN]	1	hSpCas9	negative selection	9817060
5456535	5456558	19	-	27869803	PATU8988S	viability after 35 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.1834321886800745	[2672]	[1446,996,NaN]	2	hSpCas9	negative selection	9817061
5456636	5456659	19	-	27869803	PATU8988S	viability after 35 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	-0.25626083556547863	[273]	[45,138,NaN]	-3	hSpCas9	negative selection	9817062
5455683	5455706	19	+	27869803	PATU8988S	viability after 31 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	1.0439154555201147	[177]	[49,268,NaN]	9	hSpCas9	negative selection	9899504
5456024	5456047	19	-	27869803	PATU8988S	viability after 31 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	0.5980572590938894	[511]	[246,387,NaN]	7	hSpCas9	negative selection	9899505
5456082	5456105	19	-	27869803	PATU8988S	viability after 31 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.49740125866775076	[1452]	[838,790,NaN]	6	hSpCas9	negative selection	9899506
5456279	5456302	19	-	27869803	PATU8988S	viability after 31 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-0.06893857756425792	[372]	[99,194,NaN]	-1	hSpCas9	negative selection	9899509
5456535	5456558	19	-	27869803	PATU8988S	viability after 31 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.3974477628183761	[2672]	[1307,1525,NaN]	5	hSpCas9	negative selection	9899510
5456636	5456659	19	-	27869803	PATU8988S	viability after 31 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	-0.1964844878234463	[273]	[20,189,NaN]	-2	hSpCas9	negative selection	9899511
5455683	5455706	19	+	27869803	HPAFII	viability after 35 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-0.2234670406355148	[143]	[116,0,NaN]	-1	hSpCas9	negative selection	9981953
5456024	5456047	19	-	27869803	HPAFII	viability after 35 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	-1.7480590605553046	[261]	[70,3,NaN]	-7	hSpCas9	negative selection	9981954
5456082	5456105	19	-	27869803	HPAFII	viability after 35 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	0.23096586935170715	[723]	[273,605,NaN]	1	hSpCas9	negative selection	9981955
5456279	5456302	19	-	27869803	HPAFII	viability after 35 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-0.5114933293801076	[229]	[28,140,NaN]	-3	hSpCas9	negative selection	9981958
5456535	5456558	19	-	27869803	HPAFII	viability after 35 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.7648399712405114	[1172]	[572,1499,NaN]	5	hSpCas9	negative selection	9981959
5456636	5456659	19	-	27869803	HPAFII	viability after 35 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	-0.38318517223249426	[170]	[111,14,NaN]	-2	hSpCas9	negative selection	9981960
5455683	5455706	19	+	27869803	HPAFII	viability after 31 days	GACAGCGAAGCGGGTGACCATGG	ZNRF4	ENSG00000105428	-1.1902942626252988	[143]	[66,0,NaN]	-6	hSpCas9	negative selection	10064402
5456024	5456047	19	-	27869803	HPAFII	viability after 31 days	CACGATGGCCGCCTCGAAGCCGG	ZNRF4	ENSG00000105428	-1.3363964826413453	[261]	[40,76,NaN]	-7	hSpCas9	negative selection	10064403
5456082	5456105	19	-	27869803	HPAFII	viability after 31 days	CCCTCAAGTCCTCGTAGACGTGG	ZNRF4	ENSG00000105428	-0.1935228030118501	[723]	[339,371,NaN]	-1	hSpCas9	negative selection	10064404
5456279	5456302	19	-	27869803	HPAFII	viability after 31 days	AAAGAAGGCTGATACGACCAGGG	ZNRF4	ENSG00000105428	-0.4789560106334206	[229]	[16,174,NaN]	-3	hSpCas9	negative selection	10064407
5456535	5456558	19	-	27869803	HPAFII	viability after 31 days	CCACCGACTGTTTGCACACGGGG	ZNRF4	ENSG00000105428	0.4803515128289648	[1172]	[446,1431,NaN]	3	hSpCas9	negative selection	10064408
5456636	5456659	19	-	27869803	HPAFII	viability after 31 days	CTGGACTTGAATGGCCCAGATGG	ZNRF4	ENSG00000105428	-0.2652608126867697	[170]	[109,46,NaN]	-2	hSpCas9	negative selection	10064409
5455657	5455680	19	-	28162770	P31FUJ	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	0.358558067504928	[74]	[112]	4	hSpCas9	negative selection	10273464
5455591	5455614	19	-	28162770	P31FUJ	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	-0.43443606558402936	[68]	[59]	-4	hSpCas9	negative selection	10273465
5455673	5455696	19	+	28162770	P31FUJ	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	-0.5376567859427994	[83]	[67]	-4	hSpCas9	negative selection	10273466
5455961	5455984	19	-	28162770	P31FUJ	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	0.9474647412493928	[138]	[314]	9	hSpCas9	negative selection	10273467
5455974	5455997	19	-	28162770	P31FUJ	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	-0.1790309479733978	[78]	[81]	-2	hSpCas9	negative selection	10273468
5456039	5456062	19	-	28162770	P31FUJ	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	0.31821296438343993	[85]	[125]	3	hSpCas9	negative selection	10273469
5456114	5456137	19	-	28162770	P31FUJ	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	0.7402307479853522	[134]	[264]	8	hSpCas9	negative selection	10273470
5456141	5456164	19	-	28162770	P31FUJ	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	0.11810495744474947	[137]	[175]	1	hSpCas9	negative selection	10273471
5456186	5456209	19	-	28162770	P31FUJ	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	-1.3631988416700536	[80]	[36]	-7	hSpCas9	negative selection	10273472
5456651	5456674	19	+	28162770	P31FUJ	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	0.28018034527642444	[362]	[517]	3	hSpCas9	negative selection	10273473
5455657	5455680	19	-	28162770	TF1	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10442830
5455591	5455614	19	-	28162770	TF1	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10442831
5455673	5455696	19	+	28162770	TF1	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	NaN	[NaN]	[125]	1	hSpCas9	negative selection	10442832
5455961	5455984	19	-	28162770	TF1	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	NaN	[NaN]	[221]	1	hSpCas9	negative selection	10442833
5455974	5455997	19	-	28162770	TF1	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10442834
5456039	5456062	19	-	28162770	TF1	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10442835
5456114	5456137	19	-	28162770	TF1	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	NaN	[NaN]	[201]	1	hSpCas9	negative selection	10442836
5456141	5456164	19	-	28162770	TF1	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10442837
5456186	5456209	19	-	28162770	TF1	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10442838
5456651	5456674	19	+	28162770	TF1	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	NaN	[NaN]	[405]	1	hSpCas9	negative selection	10442839
5455657	5455680	19	-	28162770	SKM1	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	0.6973724610715741	[14]	[42]	6	hSpCas9	negative selection	10612196
5455591	5455614	19	-	28162770	SKM1	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	-0.5489832036155895	[23]	[28]	-4	hSpCas9	negative selection	10612197
5455673	5455696	19	+	28162770	SKM1	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	-0.15320760649737852	[38]	[61]	-1	hSpCas9	negative selection	10612198
5455961	5455984	19	-	28162770	SKM1	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	0.005161705115778847	[30]	[54]	0	hSpCas9	negative selection	10612199
5455974	5455997	19	-	28162770	SKM1	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	0.551456697505439	[21]	[56]	5	hSpCas9	negative selection	10612200
5456039	5456062	19	-	28162770	SKM1	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	-0.23703919730084944	[21]	[32]	-2	hSpCas9	negative selection	10612201
5456114	5456137	19	-	28162770	SKM1	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	0.3371968968272484	[29]	[66]	3	hSpCas9	negative selection	10612202
5456141	5456164	19	-	28162770	SKM1	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	-0.13234181863415606	[30]	[49]	-1	hSpCas9	negative selection	10612203
5456186	5456209	19	-	28162770	SKM1	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	0.2286243750479624	[13]	[28]	2	hSpCas9	negative selection	10612204
5456651	5456674	19	+	28162770	SKM1	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	0.40932384808445016	[68]	[161]	4	hSpCas9	negative selection	10612205
5455657	5455680	19	-	28162770	SKM1	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	0.6973724610715741	[14]	[42]	6	hSpCas9	negative selection	10781562
5455591	5455614	19	-	28162770	SKM1	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	-0.5489832036155895	[23]	[28]	-4	hSpCas9	negative selection	10781563
5455673	5455696	19	+	28162770	SKM1	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	-0.15320760649737852	[38]	[61]	-1	hSpCas9	negative selection	10781564
5455961	5455984	19	-	28162770	SKM1	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	0.005161705115778847	[30]	[54]	0	hSpCas9	negative selection	10781565
5455974	5455997	19	-	28162770	SKM1	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	0.551456697505439	[21]	[56]	5	hSpCas9	negative selection	10781566
5456039	5456062	19	-	28162770	SKM1	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	-0.23703919730084944	[21]	[32]	-2	hSpCas9	negative selection	10781567
5456114	5456137	19	-	28162770	SKM1	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	0.3371968968272484	[29]	[66]	3	hSpCas9	negative selection	10781568
5456141	5456164	19	-	28162770	SKM1	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	-0.13234181863415606	[30]	[49]	-1	hSpCas9	negative selection	10781569
5456186	5456209	19	-	28162770	SKM1	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	0.2286243750479624	[13]	[28]	2	hSpCas9	negative selection	10781570
5456651	5456674	19	+	28162770	SKM1	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	0.40932384808445016	[68]	[161]	4	hSpCas9	negative selection	10781571
5455657	5455680	19	-	28162770	PL21	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	-1.087436975607265	[82]	[16]	-6	hSpCas9	negative selection	10950928
5455591	5455614	19	-	28162770	PL21	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	-1.2058527451865166	[52]	[9]	-7	hSpCas9	negative selection	10950929
5455673	5455696	19	+	28162770	PL21	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	-0.829607728904732	[97]	[23]	-5	hSpCas9	negative selection	10950930
5455961	5455984	19	-	28162770	PL21	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	-0.31587553251434447	[142]	[49]	-2	hSpCas9	negative selection	10950931
5455974	5455997	19	-	28162770	PL21	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	0.6362387292959938	[67]	[45]	5	hSpCas9	negative selection	10950932
5456039	5456062	19	-	28162770	PL21	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	-0.6812158890120608	[69]	[18]	-5	hSpCas9	negative selection	10950933
5456114	5456137	19	-	28162770	PL21	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	0.7686515944298821	[146]	[108]	6	hSpCas9	negative selection	10950934
5456141	5456164	19	-	28162770	PL21	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	0.17967551192960474	[70]	[34]	1	hSpCas9	negative selection	10950935
5456186	5456209	19	-	28162770	PL21	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	0.20013961448932038	[37]	[18]	1	hSpCas9	negative selection	10950936
5456651	5456674	19	+	28162770	PL21	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	0.4140372416603125	[218]	[126]	3	hSpCas9	negative selection	10950937
5455657	5455680	19	-	28162770	P31FUJ	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	0.358558067504928	[74]	[112]	4	hSpCas9	negative selection	11120294
5455591	5455614	19	-	28162770	P31FUJ	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	-0.43443606558402936	[68]	[59]	-4	hSpCas9	negative selection	11120295
5455673	5455696	19	+	28162770	P31FUJ	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	-0.5376567859427994	[83]	[67]	-4	hSpCas9	negative selection	11120296
5455961	5455984	19	-	28162770	P31FUJ	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	0.9474647412493928	[138]	[314]	9	hSpCas9	negative selection	11120297
5455974	5455997	19	-	28162770	P31FUJ	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	-0.1790309479733978	[78]	[81]	-2	hSpCas9	negative selection	11120298
5456039	5456062	19	-	28162770	P31FUJ	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	0.31821296438343993	[85]	[125]	3	hSpCas9	negative selection	11120299
5456114	5456137	19	-	28162770	P31FUJ	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	0.7402307479853522	[134]	[264]	8	hSpCas9	negative selection	11120300
5456141	5456164	19	-	28162770	P31FUJ	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	0.11810495744474947	[137]	[175]	1	hSpCas9	negative selection	11120301
5456186	5456209	19	-	28162770	P31FUJ	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	-1.3631988416700536	[80]	[36]	-7	hSpCas9	negative selection	11120302
5456651	5456674	19	+	28162770	P31FUJ	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	0.28018034527642444	[362]	[517]	3	hSpCas9	negative selection	11120303
5455657	5455680	19	-	28162770	OCIAML5	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	0.7703706352758223	[37]	[116]	6	hSpCas9	negative selection	11289660
5455591	5455614	19	-	28162770	OCIAML5	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	1.574943570080923	[44]	[241]	9	hSpCas9	negative selection	11289661
5455673	5455696	19	+	28162770	OCIAML5	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	-0.021991572306309326	[62]	[111]	0	hSpCas9	negative selection	11289662
5455961	5455984	19	-	28162770	OCIAML5	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	-0.13005131816376242	[96]	[159]	-1	hSpCas9	negative selection	11289663
5455974	5455997	19	-	28162770	OCIAML5	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	0.8584268119410182	[32]	[107]	7	hSpCas9	negative selection	11289664
5456039	5456062	19	-	28162770	OCIAML5	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	0.9959303356909532	[14]	[53]	8	hSpCas9	negative selection	11289665
5456114	5456137	19	-	28162770	OCIAML5	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	1.0281560742824416	[90]	[334]	8	hSpCas9	negative selection	11289666
5456141	5456164	19	-	28162770	OCIAML5	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	-0.3063253799405596	[86]	[126]	-2	hSpCas9	negative selection	11289667
5456186	5456209	19	-	28162770	OCIAML5	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	-1.5890321650302033	[64]	[38]	-7	hSpCas9	negative selection	11289668
5456651	5456674	19	+	28162770	OCIAML5	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	-0.5387004894800586	[168]	[209]	-4	hSpCas9	negative selection	11289669
5455657	5455680	19	-	28162770	EOL1	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	-0.31802253170354344	[167]	[70]	-2	hSpCas9	negative selection	11459026
5455591	5455614	19	-	28162770	EOL1	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	1.0837463664197884	[59]	[66]	8	hSpCas9	negative selection	11459027
5455673	5455696	19	+	28162770	EOL1	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	-1.9869155538278083	[157]	[20]	-8	hSpCas9	negative selection	11459028
5455961	5455984	19	-	28162770	EOL1	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	0.7883433879722233	[221]	[201]	7	hSpCas9	negative selection	11459029
5455974	5455997	19	-	28162770	EOL1	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	0.20155511995693254	[136]	[82]	1	hSpCas9	negative selection	11459030
5456039	5456062	19	-	28162770	EOL1	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	0.7512161686849728	[105]	[93]	6	hSpCas9	negative selection	11459031
5456114	5456137	19	-	28162770	EOL1	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	0.8537264343808376	[166]	[158]	7	hSpCas9	negative selection	11459032
5456141	5456164	19	-	28162770	EOL1	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	-2.949921346345607	[131]	[8]	-9	hSpCas9	negative selection	11459033
5456186	5456209	19	-	28162770	EOL1	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	0.11719284951293063	[69]	[39]	1	hSpCas9	negative selection	11459034
5456651	5456674	19	+	28162770	EOL1	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	-0.3902382540728081	[402]	[161]	-3	hSpCas9	negative selection	11459035
5455657	5455680	19	-	28162770	MOLM13	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	0.6719032735661721	[78]	[90]	5	hSpCas9	negative selection	11628392
5455591	5455614	19	-	28162770	MOLM13	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	-0.7800381318990068	[75]	[31]	-4	hSpCas9	negative selection	11628393
5455673	5455696	19	+	28162770	MOLM13	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	-0.9294461160008061	[107]	[40]	-5	hSpCas9	negative selection	11628394
5455961	5455984	19	-	28162770	MOLM13	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	0.8446099492723207	[123]	[160]	6	hSpCas9	negative selection	11628395
5455974	5455997	19	-	28162770	MOLM13	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	1.108639660451482	[92]	[144]	8	hSpCas9	negative selection	11628396
5456039	5456062	19	-	28162770	MOLM13	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	0.5003108592369565	[87]	[89]	4	hSpCas9	negative selection	11628397
5456114	5456137	19	-	28162770	MOLM13	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	0.8641170310486643	[192]	[253]	6	hSpCas9	negative selection	11628398
5456141	5456164	19	-	28162770	MOLM13	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	-0.6554930339607032	[121]	[55]	-4	hSpCas9	negative selection	11628399
5456186	5456209	19	-	28162770	MOLM13	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	-0.8998424029559084	[79]	[30]	-5	hSpCas9	negative selection	11628400
5456651	5456674	19	+	28162770	MOLM13	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	-0.5178967592357203	[403]	[203]	-3	hSpCas9	negative selection	11628401
5455657	5455680	19	-	28162770	HEL	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	0.9446291736511743	[115]	[142]	7	hSpCas9	negative selection	11797758
5455591	5455614	19	-	28162770	HEL	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	-0.11625306849584804	[43]	[25]	-1	hSpCas9	negative selection	11797759
5455673	5455696	19	+	28162770	HEL	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	0.6090557057440683	[129]	[126]	5	hSpCas9	negative selection	11797760
5455961	5455984	19	-	28162770	HEL	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	-1.3459458547718088	[126]	[31]	-7	hSpCas9	negative selection	11797761
5455974	5455997	19	-	28162770	HEL	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	1.0577763312792006	[86]	[115]	8	hSpCas9	negative selection	11797762
5456039	5456062	19	-	28162770	HEL	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	1.1375035237499351	[87]	[123]	8	hSpCas9	negative selection	11797763
5456114	5456137	19	-	28162770	HEL	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	0.1766537271311206	[162]	[117]	1	hSpCas9	negative selection	11797764
5456141	5456164	19	-	28162770	HEL	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	0.2378970998274017	[93]	[70]	2	hSpCas9	negative selection	11797765
5456186	5456209	19	-	28162770	HEL	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	0.4325211246100116	[58]	[50]	3	hSpCas9	negative selection	11797766
5456651	5456674	19	+	28162770	HEL	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	0.5605702904195307	[288]	[272]	5	hSpCas9	negative selection	11797767
5455657	5455680	19	-	28162770	MV411	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	-0.8844741247228057	[102]	[46]	-6	hSpCas9	negative selection	11967124
5455591	5455614	19	-	28162770	MV411	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	0.44537692839468424	[33]	[38]	4	hSpCas9	negative selection	11967125
5455673	5455696	19	+	28162770	MV411	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	0.37117291920501994	[66]	[72]	3	hSpCas9	negative selection	11967126
5455961	5455984	19	-	28162770	MV411	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	0.806864959396794	[113]	[167]	7	hSpCas9	negative selection	11967127
5455974	5455997	19	-	28162770	MV411	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	0.7289704618485258	[52]	[73]	6	hSpCas9	negative selection	11967128
5456039	5456062	19	-	28162770	MV411	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	-0.08320776120569606	[82]	[65]	0	hSpCas9	negative selection	11967129
5456114	5456137	19	-	28162770	MV411	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	-0.22764733216600758	[138]	[99]	-2	hSpCas9	negative selection	11967130
5456141	5456164	19	-	28162770	MV411	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	1.4237603234232383	[49]	[112]	9	hSpCas9	negative selection	11967131
5456186	5456209	19	-	28162770	MV411	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	-0.997674947053756	[63]	[26]	-6	hSpCas9	negative selection	11967132
5456651	5456674	19	+	28162770	MV411	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	1.0896087411514195	[192]	[345]	8	hSpCas9	negative selection	11967133
5455657	5455680	19	-	28162770	MONOMAC1	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	0.9967348963371265	[79]	[182]	8	hSpCas9	negative selection	12136490
5455591	5455614	19	-	28162770	MONOMAC1	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	0.3879256536616025	[29]	[44]	4	hSpCas9	negative selection	12136491
5455673	5455696	19	+	28162770	MONOMAC1	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	-0.3451354860486875	[40]	[36]	-3	hSpCas9	negative selection	12136492
5455961	5455984	19	-	28162770	MONOMAC1	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	1.0448517499026915	[62]	[148]	8	hSpCas9	negative selection	12136493
5455974	5455997	19	-	28162770	MONOMAC1	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	1.0144672581341578	[37]	[87]	8	hSpCas9	negative selection	12136494
5456039	5456062	19	-	28162770	MONOMAC1	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	-1.0997396457046387	[42]	[22]	-7	hSpCas9	negative selection	12136495
5456114	5456137	19	-	28162770	MONOMAC1	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	0.39176771995599646	[124]	[187]	4	hSpCas9	negative selection	12136496
5456141	5456164	19	-	28162770	MONOMAC1	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	1.0704434638054323	[53]	[129]	8	hSpCas9	negative selection	12136497
5456186	5456209	19	-	28162770	MONOMAC1	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	-1.9228618836205595	[42]	[12]	-8	hSpCas9	negative selection	12136498
5456651	5456674	19	+	28162770	MONOMAC1	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	-0.00017951783024322543	[170]	[195]	0	hSpCas9	negative selection	12136499
5455657	5455680	19	-	28162770	OCIAML2	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	0.3367250968154427	[13]	[97]	3	hSpCas9	negative selection	12305856
5455591	5455614	19	-	28162770	OCIAML2	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	-0.4986442014117578	[12]	[50]	-4	hSpCas9	negative selection	12305857
5455673	5455696	19	+	28162770	OCIAML2	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	1.1687804595013713	[12]	[161]	9	hSpCas9	negative selection	12305858
5455961	5455984	19	-	28162770	OCIAML2	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	-0.0997921298738525	[28]	[149]	-1	hSpCas9	negative selection	12305859
5455974	5455997	19	-	28162770	OCIAML2	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	-0.03151819098445996	[25]	[140]	0	hSpCas9	negative selection	12305860
5456039	5456062	19	-	28162770	OCIAML2	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	0.4241879380657825	[15]	[118]	4	hSpCas9	negative selection	12305861
5456114	5456137	19	-	28162770	OCIAML2	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	0.8082295477533151	[16]	[164]	7	hSpCas9	negative selection	12305862
5456141	5456164	19	-	28162770	OCIAML2	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	1.5517379877862931	[7]	[129]	9	hSpCas9	negative selection	12305863
5456186	5456209	19	-	28162770	OCIAML2	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	-0.36629316542742574	[9]	[42]	-3	hSpCas9	negative selection	12305864
5456651	5456674	19	+	28162770	OCIAML2	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	0.4408335001561815	[41]	[315]	4	hSpCas9	negative selection	12305865
5455657	5455680	19	-	28162770	OCIAML3	viability	GTGCTGCTAGGTCCCACTGGAGG	ZNRF4	ENSG00000105428	-0.9419309437444697	[27]	[43]	-6	hSpCas9	negative selection	12475222
5455591	5455614	19	-	28162770	OCIAML3	viability	GGCCTGTGGCCAGGACGCGAGGG	ZNRF4	ENSG00000105428	-1.6581379777438787	[22]	[21]	-8	hSpCas9	negative selection	12475223
5455673	5455696	19	+	28162770	OCIAML3	viability	GCAGCACACAGACAGCGAAGCGG	ZNRF4	ENSG00000105428	0.8851601963743962	[32]	[183]	7	hSpCas9	negative selection	12475224
5455961	5455984	19	-	28162770	OCIAML3	viability	GTAGCGGCGGATCAGCACGATGG	ZNRF4	ENSG00000105428	2.6210052506466868	[20]	[389]	9	hSpCas9	negative selection	12475225
5455974	5455997	19	-	28162770	OCIAML3	viability	CGAAGGTGCAGTCGTAGCGGCGG	ZNRF4	ENSG00000105428	1.375618710632318	[11]	[93]	9	hSpCas9	negative selection	12475226
5456039	5456062	19	-	28162770	OCIAML3	viability	GGAGTGGACGTTGTGCACGATGG	ZNRF4	ENSG00000105428	0.6987741089036827	[19]	[97]	6	hSpCas9	negative selection	12475227
5456114	5456137	19	-	28162770	OCIAML3	viability	GCTCACGAACACTGAGGGGATGG	ZNRF4	ENSG00000105428	-0.2720795454368007	[33]	[84]	-2	hSpCas9	negative selection	12475228
5456141	5456164	19	-	28162770	OCIAML3	viability	GACCCGCAGGTCCTGCGAGGCGG	ZNRF4	ENSG00000105428	0.35154457565346053	[26]	[103]	3	hSpCas9	negative selection	12475229
5456186	5456209	19	-	28162770	OCIAML3	viability	GTCGGGCAGGAGCAGCGCGTGGG	ZNRF4	ENSG00000105428	0.6154457253047867	[15]	[73]	5	hSpCas9	negative selection	12475230
5456651	5456674	19	+	28162770	OCIAML3	viability	AAGTCCAGCTACGCTCCCGGAGG	ZNRF4	ENSG00000105428	0.6232230758965058	[59]	[278]	5	hSpCas9	negative selection	12475231