| GR00002-A |
32104 |
FBgn0030314 |
CG11696 |
DRSC19417 |
0.005064755 |
none |
|
no |
|
Lipid storage |
COPI complex is a regulator of lipid homeostasis. |
Beller et al. |
2008 |
19067489 |
Cell line |
Kc167 |
Nuclear to lipid droplet cross-sectional area |
Fluorescence |
np |
Genome-wide |
dsRNA |
B-score |
> 2 OR < -1.7 |
Additional information about a secondary screen with non-overlaping dsRNAs |
GR00002-A |
32104 |
FBgn0030314 |
CG11696 |
DRSC19417 |
0.204301185 |
none |
|
no |
|
Lipid storage |
COPI complex is a regulator of lipid homeostasis. |
Beller et al. |
2008 |
19067489 |
Cell line |
Kc167 |
Nuclear to lipid droplet cross-sectional area |
Fluorescence |
np |
Genome-wide |
dsRNA |
B-score |
> 2 OR < -1.7 |
Additional information about a secondary screen with non-overlaping dsRNAs |
GR00002-A |
32104 |
FBgn0030314 |
CG11696 |
DRSC19417 |
0.745877086 |
none |
|
no |
|
Lipid storage |
COPI complex is a regulator of lipid homeostasis. |
Beller et al. |
2008 |
19067489 |
Cell line |
Kc167 |
Nuclear to lipid droplet cross-sectional area |
Fluorescence |
np |
Genome-wide |
dsRNA |
B-score |
> 2 OR < -1.7 |
Additional information about a secondary screen with non-overlaping dsRNAs |
GR00002-A |
32104 |
FBgn0030314 |
CG11696 |
DRSC19417 |
-0.492267552 |
none |
|
no |
|
Lipid storage |
COPI complex is a regulator of lipid homeostasis. |
Beller et al. |
2008 |
19067489 |
Cell line |
Kc167 |
Nuclear to lipid droplet cross-sectional area |
Fluorescence |
np |
Genome-wide |
dsRNA |
B-score |
> 2 OR < -1.7 |
Additional information about a secondary screen with non-overlaping dsRNAs |
GR00031-A-1 |
32104 |
|
|
HFA19417 |
0.1 |
none |
|
yes |
|
Cell growth and viability (1) |
Genome-wide RNAi analysis of growth and viability in Drosophila cells. |
Boutros et al. |
2004 |
14764878 |
Cell line |
Kc167 |
Cell number and viability |
Luminescence |
Custom-made (HFA) |
Genome-wide |
dsRNA |
Z-score |
> |
|
GR00031-A-2 |
32104 |
|
|
HFA19417 |
0.3 |
none |
|
no |
|
Cell growth and viability (2) |
Genome-wide RNAi analysis of growth and viability in Drosophila cells. |
Boutros et al. |
2004 |
14764878 |
Cell line |
S2R+ |
Cell number and viability |
Luminescence |
Custom-made (HFA) |
Genome-wide |
dsRNA |
Z-score |
> |
|
GR00044-A |
32104 |
|
CG11696 |
HFA19417 |
-2.3 |
Downregulation of JAK/STAT pathway |
|
no |
|
JAK/STAT pathway regulation |
Identification of JAK/STAT signalling components by genome-wide RNA interference. |
Mueller et al. |
2005 |
16094372 |
Cell line |
Kc167 |
JAK/STAT pathway reporter |
Luminescence |
HFA |
Genome-wide |
dsRNA |
Z-score |
> 2 OR < -2 |
|
|
32104 |
FBgn0030314 |
CG11696 |
LD18373 |
sp |
none |
|
no |
library: DGC1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GR00191-A-1 |
32104 |
CG11696 |
CG11696 |
np |
np |
Increased melanotic mass formation |
|
yes |
|
Blood cell homeostasis regulation (1) |
An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis. |
Avet-Rochex et al. |
2010 |
20540764 |
Tissue |
srp-GAL4 |
Melanotic mass formation |
Microscopy |
np |
Selected genes |
UAS-IR construct |
np |
np |
|
GR00191-A-2 |
32104 |
CG11696 |
CG11696 |
np |
np |
none |
|
yes |
|
Blood cell homeostasis regulation (2) |
An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis. |
Avet-Rochex et al. |
2010 |
20540764 |
Tissue |
hml∆-GAL4 |
Melanotic mass formation |
Microscopy |
np |
Selected genes |
UAS-IR construct |
np |
np |
|
GR00191-A-3 |
32104 |
CG11696 |
CG11696 |
np |
0 |
none |
|
yes |
|
Blood cell homeostasis regulation (3) |
An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis. |
Avet-Rochex et al. |
2010 |
20540764 |
Tissue |
srp-GAL4 |
Melanotic mass formation |
Microscopy |
np |
Selected genes |
UAS-IR construct |
Tumor index |
> |
|
GR00191-A-4 |
32104 |
CG11696 |
CG11696 |
np |
1.4 |
none |
|
yes |
|
Blood cell homeostasis regulation (4) |
An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis. |
Avet-Rochex et al. |
2010 |
20540764 |
Tissue |
hml∆-GAL4 |
Melanotic mass formation |
Microscopy |
np |
Selected genes |
UAS-IR construct |
Tumor index |
> |
|
GR00191-A-5 |
32104 |
CG11696 |
CG11696 |
np |
0 |
none |
|
no |
|
Blood cell homeostasis regulation (5) |
An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis. |
Avet-Rochex et al. |
2010 |
20540764 |
Tissue |
cg-GAL4 |
Melanotic mass formation |
Microscopy |
np |
Selected genes |
UAS-IR construct |
Tumor index |
> |
|
GR00218-S |
32104 |
CG11696 |
|
AMB26959 |
0.8 |
none |
|
no |
|
Hippo pathway regulation |
Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila |
Wehr et al. |
2013 |
23263283 |
Cell line |
S2R+ |
Hippo pathway reporter |
Luminescence |
np |
Genome-wide |
dsRNA |
Z-score |
> 3 OR < -3 |
Author-submitted data. Primary screen |
GR00239-A-1 |
32104 |
CG11696 |
|
11696R |
sp |
none |
|
no |
|
Glycosylation regulation (1) |
Identification of genes required for neural-specific glycosylation using functional genomics. |
Yamamoto-Hino et al. |
2010 |
21203496 |
Tissue |
GMR-GAL4 |
Chaoptin (Chp) protein expression, alpha1,3-fucose, alpha1,6-fucose, (GlcNAc)n, GlcNAcb1-4GlcNAc and mannose Chp glycosylation and viability |
Luminescence |
np |
Selected genes |
UAS-IR construct |
Z-score |
> 3 |
|
GR00311-A |
32104 |
FBgn0030314 |
CG11696 |
DRSC19417 |
np |
none |
|
|
|
Actin and microtubule morphology |
Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype |
Rohn et al. |
2011 |
21893601 |
Cell line |
S2R+ |
Alpha-tubulin and F-actin protein expression |
Fluorescence |
DRSC |
Genome-wide |
dsRNA |
Visual inspection |
np |
Exact phenotypes are shown in the comment section. Several genes were indicated as hits but no phenotype was provided. The screen data plus images is available at http://jcb-dataviewer.rupress.org/jcb/browse/4609/S2. |
GR00335-A |
32104 |
FBgn0030314 |
CG11696 |
JF02833 |
np |
none |
|
|
|
Germline stem cell (GSC) regulation |
A Regulatory Network of Drosophila Germline Stem Cell Self-Renewal |
Yan et al. |
2014 |
24576427 |
Tissue |
MTD-GAL4 or UAS-dcr2; nanos-GAL4 |
Spectrin and vasa protein expression |
Fluorescence |
TRiP |
Selected genes |
UAS-IR construct |
Visual inspection |
np |
More detailed phenotypes for some genes are shown in the comment. Various VALIUM vectors were used. |
|
32104 |
FBgn0030314 |
np |
np |
sp |
none |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GR00388-A |
32104 |
CG11696 |
|
BL27999 |
|
none |
|
|
|
Regulation of intestinal stem cells (ISC) |
Genome-wide RNAi Screen Identifies Networks Involved in Intestinal Stem Cell Regulation in Drosophila |
Zeng et al. |
2015 |
25704823 |
Tissue |
act5C-GAL4 |
Viability |
Visual inspection |
VDRC and BDSC |
Genome-wide |
UAS-IR construct |
np |
np |
Lethal transgenic lines identified from the primary screen were crossed with temperature-sensitive esg-GAL4 flies. Phenotypes of ISCs from the dissected midguts are shown in the "Comment" section. |