| GR00053-A |
27328 |
NM_014522 |
PCDH11X |
np |
sp |
none |
|
no |
|
Genome stability |
A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability. |
Paulsen et al. |
2009 |
19647519 |
Cell line |
HeLa |
gamma-H2AX phosphorylation and DNA content |
Fluorescence |
siARRAY human genome siRNA library |
Genome-wide |
siRNA |
p-value |
Complex criteria |
Confidence groupings from 4 to 1 (highest level of confidence in group 4) |
GR00054-A |
27328 |
NM_014522 |
PCDH11X |
np |
0.965 |
none |
|
no |
|
Combinatorial effect with paclitaxel |
Synthetic lethal screen identification of chemosensitizer loci in cancer cells. |
Whitehurst et al. |
2007 |
17429401 |
Cell line |
NCI-H1155 |
Viability (synthetic lethal) |
ATP level |
# G-005000-01 |
Genome-wide |
siRNA |
Paclitaxel/control ratio |
Complex criteria |
Additional information about 87 high-confidence hits |
GR00056-A |
27328 |
NM_014522 |
PCDH11X |
np |
0.983 |
none |
|
no |
|
Melanogenesis |
Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells. |
Ganesan et al. |
2008 |
19057677 |
Cell line |
MNT-1 |
Melanin protein expression and viability |
Absorbance and luminescence |
rp |
Genome-wide |
siRNA |
Normalized absorbance ratio |
> 2 standard deviations below mean |
Additional information about a secondary screen (retest to determine false-positive rate) |
GR00057-A-1 |
27328 |
NM_014522 |
PCDH11X |
M-013619-00 |
-0.55 |
none |
|
no |
|
Wnt/beta-catenin pathway regulation (1) |
A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer. |
Tang et al. |
2008 |
18621708 |
Cell line |
HeLa |
Wnt pathway reporter |
Luminescence |
Human siArray siRNA library |
Genome-wide |
siRNA |
Z-score |
> 4 |
Screen without Wnt3A stimulation. Additional information about secondary screens (Dharmacon and Qiagen libraries). |
GR00057-A-2 |
27328 |
NM_014522 |
PCDH11X |
M-013619-00 |
sp |
none |
|
no |
|
Wnt/beta-catenin pathway regulation (2) |
A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer. |
Tang et al. |
2008 |
18621708 |
Cell line |
HeLa |
Wnt pathway reporter |
Luminescence |
Human siArray siRNA library |
Genome-wide |
siRNA |
Complex, SP |
Complex criteria |
Screen with Wnt3A stimulation. Additional information about secondary screens (Dharmacon and Qiagen libraries). |
GR00095-A |
27328 |
NM_032967 |
PCDH11X |
np |
np |
none |
|
|
|
p53 pathway components |
A large-scale RNAi screen in human cells identifies new components of the p53 pathway |
Berns et al. |
2004 |
15042092 |
Cell line |
BJ-TERT-tsLT fibroblasts |
Proliferation |
Colony-forming cell assay |
Nki library |
Genome-wide |
shRNA |
np |
np |
|
GR00098-A-1 |
27328 |
ENSG00000102290 |
PCDH11X |
ENSG00000102290 |
sp |
none |
|
no |
|
Cell division (1) |
Genome-scale RNAi profiling of cell division in human tissue culture cells. |
Kittler et al. |
2007 |
17994010 |
Cell line |
HeLa |
Cell number and DNA content |
Laser scanning cytometry |
rp |
Genome-wide |
esiRNA |
Complex, sp |
Complex criteria |
|
GR00123-A |
27328 |
NM_032967 |
PCDH11X |
106303, 106302, 106301 |
np |
none |
|
|
|
Combinatorial effect with nutlin-3 |
An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors |
Brummelkamp et al. |
2006 |
16474381 |
Cell line |
MCF-7 |
Viability |
Fluoresence |
Nki library |
Genome-wide |
shRNA |
log2 ratio |
np |
|
GR00151-A-1 |
27328 |
ENSG00000102290 |
PCDH11X |
np |
0.857 |
none |
|
no |
|
Homologous recombination DNA double-strand break repair (HR-DSBR) (1) |
A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia. |
Słabicki et al. |
2010 |
20613862 |
Cell line |
HeLa |
(HR-DSBR) DR-GFP reporter |
Flow cytometry |
Custom-made |
Genome-wide |
esiRNA |
Z-score |
< -2 OR > 2 |
|
GR00163-A-1 |
27328 |
27328 |
PCDH11X |
M-013619-00 |
27 |
Decreased p24 protein expression |
|
no |
|
HIV-1 infection (1) |
Identification of host proteins required for HIV infection through a functional genomic screen. |
Brass et al. |
2008 |
18187620 |
Cell line |
TZM-bl |
p24 protein expression |
Fluorescence |
siARRAY siRNA Library |
Genome-wide |
siRNA |
Percentage of infected cells |
> |
|
GR00165-A |
27328 |
NM_014522, NM_032968, NM_032969, NM_032967, NM_032971, NM_032973, NM_032972 |
PCDH11X, PCDH11Y |
M-013619-00 |
np |
Metaphase cells |
|
no |
|
HeLa cell morphology |
Clustering phenotype populations by genome-wide RNAi and multiparametric imaging. |
Fuchs et al. |
2010 |
20531400 |
Cell line |
HeLa |
Cell morphology |
Fluorescence |
siGENOME |
Genome-wide |
siRNA |
Complex, sp |
np |
|
GR00180-A-1 |
27328 |
27328 |
PCDH11X |
PL-50007 |
0.673 |
none |
|
no |
|
Hepatitis C virus replication (1) |
A functional genomic screen identifies cellular cofactors of hepatitis C virus replication. |
Tai et al. |
2009 |
19286138 |
Cell line |
Huh7/Rep-Feo |
HCV replicon RNA copy number |
Luminescence |
siARRAY Human Genome siRNA Library |
Genome-wide |
siRNA |
q-value |
Complex criteria |
|
GR00184-A-1 |
27328 |
NM_014522 |
PCDH11X |
M-013619-00 |
-1.27905582920421 |
none |
|
no |
|
Self-renewal and pluripotency in human embryonic stem cells (1) |
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. |
Chia et al. |
2010 |
20953172 |
Cell line |
hESC H1 |
POU5F1 protein expression |
Fluorescence |
SMARTpool siRNA library |
Genome-wide |
siRNA |
Z-score |
< -2 |
|
GR00196-A-1 |
27328 |
ENSG00000102290 |
|
np |
sp |
none |
|
no |
|
TP53 interactions (1) |
A systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly. |
Krastev et al. |
2011 |
21642980 |
Cell line |
HCT116 ( wildtype and TP53 knockout) |
TP53 protein expression and viability |
Fluorescence |
rp |
Genome-wide |
esiRNA |
Complex, sp |
Complex criteria |
|
GR00197-A-1 |
27328 |
27328 |
PCDH11X |
M-013619-00 |
0.238698457 |
none |
|
no |
|
Human papillomavirus oncogene expression regulation (1) |
Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression. |
Smith et al. |
2010 |
20133580 |
Cell line |
C33A/BE2/18LCR c4 |
HPV18 LCR reporter activity |
Luminescence |
Human siGENOME SMARTpool library |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Phenotype strength according to Z-scores: weak: 2 - 3; moderate: 3 - 5; strong: > 5 |
|
27328 |
|
PCDH11X |
np |
np |
Decreased viability in non-small-cell lung cancer (NSCLC) lineage |
|
no |
NSCLC: no filter, 2nd best |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GR00236-A-1 |
27328 |
27328 |
PCDH11X |
M-013619-00 |
1.00654679821349 |
none |
|
no |
|
Homologous recombination DNA double-strand break repair (HR-DSBR) (1) |
A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. |
Adamson et al. |
2012 |
22344029 |
Cell line |
DR-U2OS |
(HR-DSBR) DR-GFP reporter and DNA content |
Fluorescence |
Human siGENOME siRNA (G-005000-05) |
Genome-wide |
siRNA |
Relative HR ratio |
< ~0.4 OR > 1.88 |
Cutoff values correspond 2 standard deviations from the screen-wide mean |
GR00240-S-1 |
27328 |
NM_014522 |
PCDH11X |
M-013619-00 |
0.29 |
none |
|
yes |
|
TRAIL-induced apoptosis (1) |
A synthetic lethal screen identifies FAT1 as an antagonist of caspase-8 in extrinsic apoptosis. |
Kranz and Boutros |
2014 |
24442637 |
Cell line |
U251MG |
Viability |
Luminescence |
SMART-pool siRNA |
Genome-wide |
siRNA |
Z-score |
> 4 |
Author-submitted data |
GR00240-S-2 |
27328 |
NM_014522 |
PCDH11X |
M-013619-00 |
4.49 |
Decreased viability with TRAIL |
|
no |
Z-score 3.9165 |
TRAIL-induced apoptosis (2) |
A synthetic lethal screen identifies FAT1 as an antagonist of caspase-8 in extrinsic apoptosis. |
Kranz and Boutros |
2014 |
24442637 |
Cell line |
U251MG |
Viability (synthetic lethal) |
Luminescence |
SMART-pool siRNA |
Genome-wide |
siRNA |
Differential score |
> 3.6 AND viability Z-score < 4 |
Author-submitted data. Z-scores from viability screen (1) are considered in score interpretation for this screen. |
GR00242-A-1 |
27328 |
NM_014522 |
PCDH11X |
np |
sp |
none |
|
no |
|
Selective autophagy regulation (1) |
Image-based genome-wide siRNA screen identifies selective autophagy factors. |
Orvedahl et al. |
2011 |
22020285 |
Cell line |
HeLa/GFP-LC3 |
Sindbis virus (SIN) capsid SIN-mCherry.capsid and autophagosome GFP–LC3 protein expression |
Fluorescence |
siGenome |
Genome-wide |
siRNA |
Z-score |
Complex criteria |
|
GR00247-A-1 |
27328 |
|
PCDH11X |
np |
sp |
none |
|
|
rank: 17476 |
Regulation of FOXO1 nuclear localization (1) |
Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain. |
Senapedis et al. |
2011 |
21460183 |
Cell line |
U2OS |
EGFP-FOXO1a protein expression and DNA content |
Fluorescence |
Human Genome library |
Genome-wide |
siRNA |
Complex, sp |
Complex criteria |
|
GR00249-S |
27328 |
27328 |
PCDH11X |
J-013619-05 |
1.04067 |
Increased vaccinia virus (VACV) infection |
|
no |
number of cells compared to control (%): 55.92 |
Vaccinia virus (VACV) infection |
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. |
Sivan et al. |
2013 |
23401514 |
Cell line |
HeLa |
Vaccinia virus VACV IHD-J/GFP protein expression and DNA content |
Fluorescence |
Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %. |
GR00249-S |
27328 |
27328 |
PCDH11X |
M-013619-00 |
0.33248 |
none |
|
no |
number of cells compared to control (%): 64.99 |
Vaccinia virus (VACV) infection |
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. |
Sivan et al. |
2013 |
23401514 |
Cell line |
HeLa |
Vaccinia virus VACV IHD-J/GFP protein expression and DNA content |
Fluorescence |
Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %. |
GR00249-S |
27328 |
27328 |
PCDH11X |
s26157 |
-1.59266 |
Decreased viability |
|
no |
number of cells compared to control (%): 44.22 |
Vaccinia virus (VACV) infection |
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. |
Sivan et al. |
2013 |
23401514 |
Cell line |
HeLa |
Vaccinia virus VACV IHD-J/GFP protein expression and DNA content |
Fluorescence |
Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %. |
GR00249-S |
27328 |
27328 |
PCDH11X |
s26158 |
-1.25348 |
none |
|
no |
number of cells compared to control (%): 99.08 |
Vaccinia virus (VACV) infection |
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. |
Sivan et al. |
2013 |
23401514 |
Cell line |
HeLa |
Vaccinia virus VACV IHD-J/GFP protein expression and DNA content |
Fluorescence |
Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %. |
GR00249-S |
27328 |
27328 |
PCDH11X |
s26159 |
1.76026 |
Increased vaccinia virus (VACV) infection |
|
no |
number of cells compared to control (%): 78.94 |
Vaccinia virus (VACV) infection |
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. |
Sivan et al. |
2013 |
23401514 |
Cell line |
HeLa |
Vaccinia virus VACV IHD-J/GFP protein expression and DNA content |
Fluorescence |
Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %. |
GR00253-A |
27328 |
NM_014522 |
PCDH11X |
np |
0.139 |
none |
|
|
|
hepcidin regulation |
Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling. |
Mleczko-Sanecka et al. |
2014 |
24385536 |
Cell line |
Huh7 |
hepcidin::fluc mRNA expression |
Luminescence |
siGenome siARRAY SMARTpool |
Genome-wide |
siRNA |
Z-score |
> |
Cutoff < |
GR00255-A-1 |
27328 |
27328 |
PCDH11X |
TRCN0000056353, TRCN0000056354, TRCN0000056355, TRCN0000056356, TRCN0000056357 |
-0.380905815 |
none |
|
|
|
Negative genetic interactions (1) |
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. |
Vizeacoumar et al. |
2013 |
24104479 |
Cell line |
HCT116 |
shRNA abundance |
Microarray |
np |
Genome-wide |
shRNA |
differential Gene Activity Ranking Profile (dGARP) |
< -1.0 |
HCT116 BLM-/- and HCT116 BLM+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells) |
GR00255-A-2 |
27328 |
27328 |
PCDH11X |
TRCN0000056353, TRCN0000056354, TRCN0000056355, TRCN0000056356, TRCN0000056357 |
-0.193673542 |
none |
|
|
|
Negative genetic interactions (2) |
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. |
Vizeacoumar et al. |
2013 |
24104479 |
Cell line |
HCT116 |
shRNA abundance |
Microarray |
np |
Genome-wide |
shRNA |
differential Gene Activity Ranking Profile (dGARP) |
< -1.0 |
HCT116 MUS81-/- and HCT116 MUS81+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells) |
GR00255-A-3 |
27328 |
27328 |
PCDH11X |
TRCN0000056353, TRCN0000056354, TRCN0000056355, TRCN0000056356, TRCN0000056357 |
-0.495893262 |
none |
|
|
|
Negative genetic interactions (3) |
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. |
Vizeacoumar et al. |
2013 |
24104479 |
Cell line |
HCT116 |
shRNA abundance |
Microarray |
np |
Genome-wide |
shRNA |
differential Gene Activity Ranking Profile (dGARP) |
< -1.2 |
HCT116 PTEN-/- and HCT116 PTEN+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells) |
GR00255-A-4 |
27328 |
27328 |
PCDH11X |
TRCN0000056353, TRCN0000056354, TRCN0000056355, TRCN0000056356, TRCN0000056357 |
0.357088344 |
none |
|
|
|
Negative genetic interactions (4) |
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. |
Vizeacoumar et al. |
2013 |
24104479 |
Cell line |
HCT116 |
shRNA abundance |
Microarray |
np |
Genome-wide |
shRNA |
differential Gene Activity Ranking Profile (dGARP) |
< -1.2 |
HCT116 PTTG1-/- and HCT116 PTTG1+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells) |
GR00255-A-5 |
27328 |
27328 |
PCDH11X |
TRCN0000056353, TRCN0000056354, TRCN0000056355, TRCN0000056356, TRCN0000056357 |
0.165211146 |
none |
|
|
|
Negative genetic interactions (5) |
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. |
Vizeacoumar et al. |
2013 |
24104479 |
Cell line |
HCT116 |
shRNA abundance |
Microarray |
np |
Genome-wide |
shRNA |
differential Gene Activity Ranking Profile (dGARP) |
< -0.8 |
HCT116 KRASG13D/- and HCT116 KRAS+/- cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells) |
GR00293-A |
27328 |
|
PCDH11X |
np |
-0.181 |
none |
|
|
|
Combinatorial effect with paclitaxel |
Mechanisms Promoting Escape from Mitotic Stress−Induced Tumor Cell Death |
Sinnott et al. |
2014 |
24860162 |
Cell line |
HCC366 |
Viability |
Luminescence |
Thermo-Fisher |
Genome-wide |
siRNA |
Z-score |
< -2.5 |
Final hits according to the author are indicated in the comment. |
GR00300-A |
27328 |
|
PCDH11X |
TRCN0000056357, TRCN0000056356, TRCN0000056355, TRCN0000056354, TRCN0000056353 |
0 |
none |
|
|
|
Combinatorial effect with RAF inhibitor PLX4720 |
A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition. |
Whittaker et al. |
2013 |
23288408 |
Cell line |
A375 |
shRNA abundance |
Sequencing |
TRC |
Genome-wide |
shRNA |
Number of shRNAs ranked Top1000 |
> 2 |
The A375 cell line used here harbours the BRAF V600E mutation and is therefore sensitive to RAF inhibitors. |
GR00303-A |
27328 |
NM_014522 |
PCDH11X |
np |
0.86 |
none |
|
|
|
Clear cell renal cell carcinoma (ccRCC) survival regulation |
Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target |
Gerlinger et al. |
2012 |
22362593 |
Cell line |
VHL-deficient RCC4 |
Proliferation and Viability |
Fluorescence |
np |
Genome-wide |
siRNA |
Z-score |
< |
In the phenotype data duplicates were in the original document, which have been removed. |
|
27328 |
27328 |
PCDH11X |
np |
73.2 |
Inconclusive |
|
|
54,7% viability |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GR00313-A |
27328 |
NM_014522 |
PCDH11X |
np |
-0.64 |
none |
|
|
|
TNF-alpha pathway regulation |
A Genome-Wide RNA Interference Screen Identifies Caspase 4 as a Factor Required for Tumor Necrosis Factor Alpha Signaling. |
Nickles et al. |
2012 |
22733992 |
Cell line |
HEK293T |
NFkappaB pathway reporter |
Luminescence |
Qiagen |
Genome-wide |
siRNA |
Z-score |
< |
Additional filters were a reduction in firefly luciferase levels by at least 50% compared to the mean of the experiment and a concomitant reduction of renilla luciferase expression of not more than 30%. |
GR00318-A |
27328 |
27328 |
PCDH11X |
np |
1.368 |
none |
|
|
siRNA set: druggable genome |
Huntingtin toxicity |
A Genome-Scale RNA–Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington’s Disease |
Miller et al. |
2012 |
23209424 |
Cell line |
HEK293T |
Caspase 3/7 activity |
Fluorescence |
Dharmacon |
Selected genes |
siRNA |
Sum of normalized caspase 3/7 activity mean and standard error |
< 0.683 |
HEK293T cells were cotransfected with mutant Huntingtin fused to GFP (Htt1-558141Q-GFP). |
GR00359-A |
27328 |
27328 |
PCDH11X |
M-013619-00 |
-5.163673540619324 |
Strongly decreased NFAT1-GFP nuclear translocation |
|
|
|
NFAT activation |
An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry |
Sharma et al. |
2013 |
23792561 |
Cell line |
HeLa |
NFAT1-GFP nuclear translocation |
Fluorescence |
Dharmacon siGENOME |
Genome-wide |
siRNA |
Z-score |
Strong: < |
HeLa cells stably expressed NFAT1-GFP. Libraries were Dharmacon siGENOME v2007 and v2010 |
GR00362-A |
27328 |
27328 |
PCDH11X |
np |
np |
Synthetic lethal with vaccinia virus (VACV) infection |
|
|
|
Vaccinia virus (VACV) replication |
A loss of function analysis of host factors influencing Vaccina virus replication by RNA interference |
Beard et al. |
2014 |
2401222 |
Cell line |
HeLa |
VACV-A5eGFP expression |
Fluorescence |
SMARTpools, Dharmacon |
Genome-wide |
siRNA |
Z-score |
< |
Genes were prescreened for viability, those declared as lethal were not screened for fluorescence. |
GR00366-A-1 |
27328 |
|
PCDH11X |
|
-0.678444887191916 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (1) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
22RV1_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-1 |
27328 |
|
PCDH11X |
|
-0.829984107209616 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (1) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
22RV1_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-1 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.229928277208961 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (1) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
22RV1_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-10 |
27328 |
|
PCDH11X |
|
0.95432005521393 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (10) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ACHN_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-10 |
27328 |
|
PCDH11X |
|
-1.26562661423115 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (10) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ACHN_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-10 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.632816658294823 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (10) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ACHN_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-100 |
27328 |
|
PCDH11X |
|
-0.28841493968581 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (100) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LAMA84_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-100 |
27328 |
|
PCDH11X |
|
-1.46634246447982 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (100) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LAMA84_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-100 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.264679235985349 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (100) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LAMA84_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-101 |
27328 |
|
PCDH11X |
|
-1.18623649862776 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (101) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LK2_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-101 |
27328 |
|
PCDH11X |
|
0.692933755609778 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (101) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LK2_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-101 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.1037435931746 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (101) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LK2_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-102 |
27328 |
|
PCDH11X |
|
0.99933380235997 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (102) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN215_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-102 |
27328 |
|
PCDH11X |
|
-0.133848502417042 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (102) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN215_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-102 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.110423901607927 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (102) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN215_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-103 |
27328 |
|
PCDH11X |
|
0.0987986878099827 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (103) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN229_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-103 |
27328 |
|
PCDH11X |
|
-1.01155680453871 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (103) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN229_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-103 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.769532443628224 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (103) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN229_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-104 |
27328 |
|
PCDH11X |
|
1.18486564456704 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (104) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN235_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-104 |
27328 |
|
PCDH11X |
|
0.369536309047284 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (104) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN235_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-104 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.825835232430375 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (104) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN235_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-105 |
27328 |
|
PCDH11X |
|
0.961092517599398 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (105) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN319_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-105 |
27328 |
|
PCDH11X |
|
0.280821634770264 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (105) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN319_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-105 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.420456574029541 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (105) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN319_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-106 |
27328 |
|
PCDH11X |
|
0.18381031226643 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (106) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN340_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-106 |
27328 |
|
PCDH11X |
|
-0.18665042765523 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (106) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN340_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-106 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.257456567042514 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (106) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN340_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-107 |
27328 |
|
PCDH11X |
|
1.11626933299739 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (107) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN382_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-107 |
27328 |
|
PCDH11X |
|
-1.02124619418664 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (107) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN382_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-107 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.253390659848324 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (107) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN382_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-108 |
27328 |
|
PCDH11X |
|
-0.561042924853771 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (108) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN428_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-108 |
27328 |
|
PCDH11X |
|
0.412456014508005 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (108) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN428_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-108 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.401723819381186 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (108) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN428_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-109 |
27328 |
|
PCDH11X |
|
-0.184384609346338 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (109) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN443_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-109 |
27328 |
|
PCDH11X |
|
-0.0605641566888306 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (109) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN443_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-109 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.417004823947679 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (109) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN443_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-11 |
27328 |
|
PCDH11X |
|
1.36418379583158 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (11) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AGS_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-11 |
27328 |
|
PCDH11X |
|
-0.369341754398356 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (11) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AGS_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-11 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.161847516921179 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (11) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AGS_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-110 |
27328 |
|
PCDH11X |
|
0.712534449873625 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (110) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN464_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-110 |
27328 |
|
PCDH11X |
|
1.07017585720095 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (110) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN464_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-110 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.610463824305056 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (110) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN464_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-111 |
27328 |
|
PCDH11X |
|
0.920099553774971 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (111) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LNZ308_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-111 |
27328 |
|
PCDH11X |
|
-0.279279037438281 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (111) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LNZ308_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-111 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.628804995515392 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (111) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LNZ308_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-112 |
27328 |
|
PCDH11X |
|
0.419590296500441 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (112) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LOVO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-112 |
27328 |
|
PCDH11X |
|
-0.297626699513372 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (112) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LOVO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-112 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.570822124210769 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (112) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LOVO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-113 |
27328 |
|
PCDH11X |
|
-0.768374315397005 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (113) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS411N_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-113 |
27328 |
|
PCDH11X |
|
1.93714419686791 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (113) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS411N_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-113 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.20356914144384 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (113) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS411N_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-114 |
27328 |
|
PCDH11X |
|
-0.638385340270777 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (114) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS513_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-114 |
27328 |
|
PCDH11X |
|
-1.32489702517444 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (114) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS513_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-114 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.38140323469529 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (114) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS513_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-115 |
27328 |
|
PCDH11X |
|
-1.5105174273959 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (115) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MCF7_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-115 |
27328 |
|
PCDH11X |
|
2.34135882389312 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (115) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MCF7_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-115 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.651495841014761 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (115) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MCF7_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-116 |
27328 |
|
PCDH11X |
|
-0.573552822190676 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (116) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MDAMB453_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-116 |
27328 |
|
PCDH11X |
|
0.618038800035063 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (116) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MDAMB453_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-116 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.487567320411987 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (116) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MDAMB453_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-117 |
27328 |
|
PCDH11X |
|
-0.0268885937927389 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (117) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MIAPACA2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-117 |
27328 |
|
PCDH11X |
|
-0.0636310014249179 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (117) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MIAPACA2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-117 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.517149527284475 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (117) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MIAPACA2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-118 |
27328 |
|
PCDH11X |
|
0.192023927587145 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (118) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MKN7_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-118 |
27328 |
|
PCDH11X |
|
1.30036527141145 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (118) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MKN7_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-118 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.923362608427723 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (118) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MKN7_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-119 |
27328 |
|
PCDH11X |
|
-0.202877976085941 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (119) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-119 |
27328 |
|
PCDH11X |
|
-0.178145060839983 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (119) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-119 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0657549345228807 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (119) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-12 |
27328 |
|
PCDH11X |
|
1.33749419328726 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (12) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AM38_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-12 |
27328 |
|
PCDH11X |
|
-1.63503113977416 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (12) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AM38_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-12 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.773578430525079 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (12) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AM38_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-120 |
27328 |
|
PCDH11X |
|
-0.28476496137566 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (120) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MOLM13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-120 |
27328 |
|
PCDH11X |
|
-0.446570714721702 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (120) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MOLM13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-120 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.145394485350887 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (120) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MOLM13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-121 |
27328 |
|
PCDH11X |
|
1.06586156556098 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (121) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-121 |
27328 |
|
PCDH11X |
|
0.143871026063573 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (121) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-121 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.55315643478208 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (121) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-122 |
27328 |
|
PCDH11X |
|
1.94605549050545 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (122) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-122 |
27328 |
|
PCDH11X |
|
-0.481463802452256 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (122) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-122 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.837897853355452 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (122) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-123 |
27328 |
|
PCDH11X |
|
1.66479991518025 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (123) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MV411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-123 |
27328 |
|
PCDH11X |
|
-1.19196454551963 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (123) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MV411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-123 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0750761111817485 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (123) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MV411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-124 |
27328 |
|
PCDH11X |
|
1.17969667635865 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (124) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-124 |
27328 |
|
PCDH11X |
|
-1.18442011097209 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (124) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-124 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.187545431090197 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (124) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-125 |
27328 |
|
PCDH11X |
|
0.453516803612782 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (125) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NB4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-125 |
27328 |
|
PCDH11X |
|
-1.6595886139001 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (125) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NB4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-125 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.147127163251304 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (125) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NB4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-126 |
27328 |
|
PCDH11X |
|
0.00643617634175257 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (126) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1299_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-126 |
27328 |
|
PCDH11X |
|
1.00580855419554 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (126) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1299_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-126 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
1.53491490255658 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (126) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1299_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-127 |
27328 |
|
PCDH11X |
|
-0.912855808242041 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (127) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1437_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-127 |
27328 |
|
PCDH11X |
|
3.06562370143108 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (127) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1437_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-127 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.0521510344702036 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (127) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1437_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-128 |
27328 |
|
PCDH11X |
|
-0.671487798275243 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (128) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1650_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-128 |
27328 |
|
PCDH11X |
|
0.0351222219521729 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (128) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1650_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-128 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.243363062898137 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (128) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1650_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-129 |
27328 |
|
PCDH11X |
|
-0.193801772370754 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (129) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1792_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-129 |
27328 |
|
PCDH11X |
|
0.0591555350221391 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (129) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1792_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-129 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.380688229381547 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (129) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1792_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-13 |
27328 |
|
PCDH11X |
|
1.47753020036825 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (13) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AML193_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-13 |
27328 |
|
PCDH11X |
|
-0.988546382193518 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (13) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AML193_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-13 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.278005510012392 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (13) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AML193_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-130 |
27328 |
|
PCDH11X |
|
1.89299681578834 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (130) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH196_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-130 |
27328 |
|
PCDH11X |
|
-0.250009511906327 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (130) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH196_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-130 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.46260842139916 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (130) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH196_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-131 |
27328 |
|
PCDH11X |
|
-0.567891373907087 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (131) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1975_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-131 |
27328 |
|
PCDH11X |
|
-0.918970420566965 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (131) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1975_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-131 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0764794327027759 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (131) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1975_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-132 |
27328 |
|
PCDH11X |
|
-1.02545065275341 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (132) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2052_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-132 |
27328 |
|
PCDH11X |
|
-1.37149333798186 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (132) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2052_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-132 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0639266432323768 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (132) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2052_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-133 |
27328 |
|
PCDH11X |
|
0.649656526680991 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (133) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2122_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-133 |
27328 |
|
PCDH11X |
|
0.333744356480772 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (133) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2122_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-133 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0671613295494598 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (133) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2122_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-134 |
27328 |
|
PCDH11X |
|
-0.696321221321649 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (134) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2171_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-134 |
27328 |
|
PCDH11X |
|
-0.753982240679325 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (134) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2171_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-134 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.391661762159936 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (134) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2171_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-135 |
27328 |
|
PCDH11X |
|
1.24341529518334 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (135) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-135 |
27328 |
|
PCDH11X |
|
0.00183635684841221 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (135) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-135 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.871364557907358 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (135) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-136 |
27328 |
|
PCDH11X |
|
-0.725671345014191 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (136) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2452_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-136 |
27328 |
|
PCDH11X |
|
0.0915181476973699 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (136) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2452_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-136 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.289145312612761 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (136) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2452_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-137 |
27328 |
|
PCDH11X |
|
0.683317720775616 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (137) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH441_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-137 |
27328 |
|
PCDH11X |
|
2.2807154958473 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (137) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH441_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-137 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.246973225087757 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (137) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH441_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-138 |
27328 |
|
PCDH11X |
|
0.0902592698716394 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (138) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH508_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-138 |
27328 |
|
PCDH11X |
|
0.368902815431492 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (138) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH508_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-138 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.281902410172174 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (138) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH508_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-139 |
27328 |
|
PCDH11X |
|
1.96255119772812 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (139) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH660_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-139 |
27328 |
|
PCDH11X |
|
2.72586845952497 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (139) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH660_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-139 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.222691364342933 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (139) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH660_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-14 |
27328 |
|
PCDH11X |
|
-0.982812751482112 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (14) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ASPC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-14 |
27328 |
|
PCDH11X |
|
-1.2540907624987 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (14) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ASPC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-14 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.873369172212069 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (14) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ASPC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-140 |
27328 |
|
PCDH11X |
|
-0.867839988026759 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (140) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH661_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-140 |
27328 |
|
PCDH11X |
|
0.406838647229776 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (140) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH661_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-140 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.116664383912814 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (140) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH661_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-141 |
27328 |
|
PCDH11X |
|
0.217332776366042 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (141) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH716_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-141 |
27328 |
|
PCDH11X |
|
1.72332270339811 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (141) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH716_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-141 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.036893186708336 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (141) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH716_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-142 |
27328 |
|
PCDH11X |
|
-0.782343950479754 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (142) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH838_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-142 |
27328 |
|
PCDH11X |
|
-0.528933535937405 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (142) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH838_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-142 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.2799708437329 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (142) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH838_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-143 |
27328 |
|
PCDH11X |
|
0.0665649922026243 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (143) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIN87_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-143 |
27328 |
|
PCDH11X |
|
0.64587694704315 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (143) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIN87_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-143 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.663048860243551 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (143) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIN87_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-144 |
27328 |
|
PCDH11X |
|
-0.698805892734622 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (144) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NIHOVCAR3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-144 |
27328 |
|
PCDH11X |
|
0.334481814568296 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (144) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NIHOVCAR3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-144 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.11664688919822 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (144) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NIHOVCAR3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-145 |
27328 |
|
PCDH11X |
|
1.07688035846146 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (145) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NOMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-145 |
27328 |
|
PCDH11X |
|
-0.68336105336339 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (145) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NOMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-145 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.584075138326489 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (145) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NOMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-146 |
27328 |
|
PCDH11X |
|
-0.859051996707854 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (146) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OAW42_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-146 |
27328 |
|
PCDH11X |
|
0.0278600690627449 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (146) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OAW42_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-146 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.163884358867535 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (146) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OAW42_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-147 |
27328 |
|
PCDH11X |
|
0.854341443364184 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (147) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-147 |
27328 |
|
PCDH11X |
|
-1.61528719869301 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (147) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-147 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.247808456820545 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (147) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-148 |
27328 |
|
PCDH11X |
|
1.90617049801579 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (148) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-148 |
27328 |
|
PCDH11X |
|
2.42349476036655 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (148) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-148 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-1.00585965340941 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (148) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-149 |
27328 |
|
PCDH11X |
|
-1.91055501403504 |
Decreased shRNA abundance (Z-score < -2) |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (149) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-149 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.393786781783003 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (149) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-149 |
27328 |
|
PCDH11X |
|
1.29908268127464 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (149) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-15 |
27328 |
|
PCDH11X |
|
0.305281776463322 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (15) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT20_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-15 |
27328 |
|
PCDH11X |
|
0.675766987014707 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (15) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT20_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-15 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.0511674995262021 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (15) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT20_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-150 |
27328 |
|
PCDH11X |
|
-1.0610064482145 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (150) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OE33_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-150 |
27328 |
|
PCDH11X |
|
-0.632265386265038 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (150) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OE33_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-150 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.00332944014842463 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (150) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OE33_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-151 |
27328 |
|
PCDH11X |
|
-1.03837063294564 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (151) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OELE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-151 |
27328 |
|
PCDH11X |
|
-0.155918929780441 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (151) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OELE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-151 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.401032523691638 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (151) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OELE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-152 |
27328 |
|
PCDH11X |
|
1.98942924353669 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (152) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OPM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-152 |
27328 |
|
PCDH11X |
|
-0.745406742260404 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (152) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OPM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-152 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.377324694573048 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (152) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OPM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-153 |
27328 |
|
PCDH11X |
|
1.44917805087828 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (153) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV7_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-153 |
27328 |
|
PCDH11X |
|
1.20840645160326 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (153) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV7_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-153 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.17631619285614 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (153) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV7_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-154 |
27328 |
|
PCDH11X |
|
-0.0834934979636145 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (154) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV90_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-154 |
27328 |
|
PCDH11X |
|
0.566864523998686 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (154) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV90_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-154 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.49010161149385 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (154) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV90_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-155 |
27328 |
|
PCDH11X |
|
-0.650034718419031 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (155) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-155 |
27328 |
|
PCDH11X |
|
0.926338912282374 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (155) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-155 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.333302842461479 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (155) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-156 |
27328 |
|
PCDH11X |
|
-1.5117184928396 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (156) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-156 |
27328 |
|
PCDH11X |
|
-0.482974373641786 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (156) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-156 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.652476575584205 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (156) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-157 |
27328 |
|
PCDH11X |
|
-1.28385388963918 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (157) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVISE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-157 |
27328 |
|
PCDH11X |
|
-0.708804670592128 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (157) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVISE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-157 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.165931635033591 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (157) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVISE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-158 |
27328 |
|
PCDH11X |
|
0.0104475466095058 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (158) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0327_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-158 |
27328 |
|
PCDH11X |
|
0.856849851655477 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (158) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0327_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-158 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.328986066706958 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (158) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0327_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-159 |
27328 |
|
PCDH11X |
|
-1.22571542003843 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (159) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0813_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-159 |
27328 |
|
PCDH11X |
|
-0.127530102653645 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (159) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0813_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-159 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.757061702254158 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (159) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0813_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-16 |
27328 |
|
PCDH11X |
|
0.00806539822100226 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (16) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT474_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-16 |
27328 |
|
PCDH11X |
|
1.13316401022569 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (16) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT474_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-16 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.0178448860282582 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (16) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT474_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-160 |
27328 |
|
PCDH11X |
|
-0.929175228623684 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (160) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC1005_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-160 |
27328 |
|
PCDH11X |
|
-0.253436923861055 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (160) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC1005_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-160 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.211856322968946 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (160) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC1005_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-161 |
27328 |
|
PCDH11X |
|
0.164539828313348 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (161) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PLB985_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-161 |
27328 |
|
PCDH11X |
|
0.0978746279954449 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (161) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PLB985_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-161 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.364706185735306 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (161) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PLB985_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-162 |
27328 |
|
PCDH11X |
|
0.870777150022865 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (162) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PSN1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-162 |
27328 |
|
PCDH11X |
|
-0.345045795153473 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (162) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PSN1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-162 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.50936421476951 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (162) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PSN1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-163 |
27328 |
|
PCDH11X |
|
0.78161864464767 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (163) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
QGP1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-163 |
27328 |
|
PCDH11X |
|
-0.72415058713003 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (163) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
QGP1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-163 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.433272708507078 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (163) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
QGP1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-164 |
27328 |
|
PCDH11X |
|
1.01706545907876 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (164) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-164 |
27328 |
|
PCDH11X |
|
-0.874720299574405 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (164) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-164 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
1.14038658096182 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (164) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-165 |
27328 |
|
PCDH11X |
|
1.7611264199865 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (165) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKN_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-165 |
27328 |
|
PCDH11X |
|
-0.370293780425128 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (165) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKN_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-165 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.47671433042141 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (165) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKN_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-166 |
27328 |
|
PCDH11X |
|
0.0607373762426038 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (166) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-166 |
27328 |
|
PCDH11X |
|
-0.227070048480061 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (166) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-166 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.23619590434282 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (166) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-167 |
27328 |
|
PCDH11X |
|
-1.2193663352956 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (167) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMGI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-167 |
27328 |
|
PCDH11X |
|
-1.29395846222575 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (167) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMGI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-167 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.408099221228181 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (167) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMGI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-168 |
27328 |
|
PCDH11X |
|
1.29874120747552 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (168) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMUGS_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-168 |
27328 |
|
PCDH11X |
|
0.208631901888071 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (168) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMUGS_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-168 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
1.03081001739517 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (168) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMUGS_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-169 |
27328 |
|
PCDH11X |
|
1.37721293347855 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (169) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RS411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-169 |
27328 |
|
PCDH11X |
|
-0.0477452525936275 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (169) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RS411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-169 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.469045290371191 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (169) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RS411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-17 |
27328 |
|
PCDH11X |
|
-0.64543479258238 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (17) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BXPC3_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-17 |
27328 |
|
PCDH11X |
|
-0.00862993317640004 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (17) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BXPC3_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-17 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.144162859428912 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (17) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BXPC3_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-170 |
27328 |
|
PCDH11X |
|
-1.29727521697331 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (170) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RT112_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-170 |
27328 |
|
PCDH11X |
|
0.688748794223391 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (170) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RT112_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-170 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-1.41647542106632 |
Decreased shRNA abundance (Z-score < -2) |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (170) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RT112_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-171 |
27328 |
|
PCDH11X |
|
1.10847878742607 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (171) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-171 |
27328 |
|
PCDH11X |
|
-1.50566482776249 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (171) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-171 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.595935915497273 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (171) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-172 |
27328 |
|
PCDH11X |
|
0.520521155882604 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (172) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF126_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-172 |
27328 |
|
PCDH11X |
|
1.06027010326364 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (172) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF126_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-172 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.778977778077985 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (172) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF126_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-173 |
27328 |
|
PCDH11X |
|
-2.10264493693598 |
Decreased shRNA abundance (Z-score < -2) |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (173) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-173 |
27328 |
|
PCDH11X |
|
2.6992607421358 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (173) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-173 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.108275569001279 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (173) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-174 |
27328 |
|
PCDH11X |
|
0.636392073992782 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (174) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF295_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-174 |
27328 |
|
PCDH11X |
|
0.217624468237661 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (174) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF295_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-174 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.281047531113715 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (174) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF295_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-175 |
27328 |
|
PCDH11X |
|
-0.700576552739787 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (175) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF767_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-175 |
27328 |
|
PCDH11X |
|
0.543665577678086 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (175) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF767_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-175 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.998733011335437 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (175) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF767_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-176 |
27328 |
|
PCDH11X |
|
1.31977683930998 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (176) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SJSA1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-176 |
27328 |
|
PCDH11X |
|
-0.698089776383268 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (176) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SJSA1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-176 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-1.05953409664322 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (176) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SJSA1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-177 |
27328 |
|
PCDH11X |
|
0.787293901439387 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (177) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKCO1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-177 |
27328 |
|
PCDH11X |
|
1.35636435365726 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (177) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKCO1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-177 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.670359423199721 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (177) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKCO1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-178 |
27328 |
|
PCDH11X |
|
0.557478642977625 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (178) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMEL5_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-178 |
27328 |
|
PCDH11X |
|
-0.697243621942372 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (178) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMEL5_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-178 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.543942472257642 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (178) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMEL5_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-179 |
27328 |
|
PCDH11X |
|
-0.745477407900464 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (179) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-179 |
27328 |
|
PCDH11X |
|
0.867206700476881 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (179) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-179 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0383393681647873 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (179) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-18 |
27328 |
|
PCDH11X |
|
-0.946806791771304 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (18) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C2BBE1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-18 |
27328 |
|
PCDH11X |
|
0.589613687243097 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (18) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C2BBE1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-18 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.17667663184464 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (18) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C2BBE1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-180 |
27328 |
|
PCDH11X |
|
2.85359921776345 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (180) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKNO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-180 |
27328 |
|
PCDH11X |
|
-0.938139353852616 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (180) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKNO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-180 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.689312061468465 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (180) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKNO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-181 |
27328 |
|
PCDH11X |
|
-0.663988759361434 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (181) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-181 |
27328 |
|
PCDH11X |
|
1.36445352801559 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (181) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-181 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.067876814429951 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (181) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-182 |
27328 |
|
PCDH11X |
|
-0.465457686700596 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (182) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKRC20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-182 |
27328 |
|
PCDH11X |
|
-1.05619445664979 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (182) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKRC20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-182 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.393519024480891 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (182) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKRC20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-183 |
27328 |
|
PCDH11X |
|
-0.686638987646852 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (183) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-183 |
27328 |
|
PCDH11X |
|
0.333485793875365 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (183) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-183 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.729302846972835 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (183) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-184 |
27328 |
|
PCDH11X |
|
0.615342977349381 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (184) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR21_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-184 |
27328 |
|
PCDH11X |
|
-0.966972662616695 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (184) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR21_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-184 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.992327981715194 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (184) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR21_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-185 |
27328 |
|
PCDH11X |
|
-0.473225821869512 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (185) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR23_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-185 |
27328 |
|
PCDH11X |
|
-0.819785526971486 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (185) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR23_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-185 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-1.00673548929094 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (185) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR23_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-186 |
27328 |
|
PCDH11X |
|
-0.993363043744162 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (186) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR24_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-186 |
27328 |
|
PCDH11X |
|
-1.02534209895348 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (186) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR24_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-186 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.374774095985754 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (186) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR24_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-187 |
27328 |
|
PCDH11X |
|
-0.327352948930134 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (187) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR25_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-187 |
27328 |
|
PCDH11X |
|
-0.270173440052743 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (187) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR25_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-187 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.150195589710947 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (187) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR25_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-188 |
27328 |
|
PCDH11X |
|
-0.353080925783444 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (188) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR26_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-188 |
27328 |
|
PCDH11X |
|
-1.00816290197684 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (188) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR26_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-188 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.67547592455297 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (188) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR26_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-189 |
27328 |
|
PCDH11X |
|
1.34843515961743 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (189) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU1105_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-189 |
27328 |
|
PCDH11X |
|
-0.683452222990934 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (189) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU1105_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-189 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.55946440514408 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (189) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU1105_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-19 |
27328 |
|
PCDH11X |
|
1.51329237930383 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (19) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C32_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-19 |
27328 |
|
PCDH11X |
|
-1.34125336495743 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (19) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C32_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-19 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
1.13809268903174 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (19) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C32_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-190 |
27328 |
|
PCDH11X |
|
0.0121849393006999 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (190) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU840_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-190 |
27328 |
|
PCDH11X |
|
1.19388996593558 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (190) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU840_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-190 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.270448908746424 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (190) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU840_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-191 |
27328 |
|
PCDH11X |
|
0.504476075353473 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (191) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-191 |
27328 |
|
PCDH11X |
|
0.577751658985313 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (191) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-191 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.159174492281514 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (191) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-192 |
27328 |
|
PCDH11X |
|
-0.779089856972819 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (192) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC2A_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-192 |
27328 |
|
PCDH11X |
|
0.690722544725287 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (192) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC2A_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-192 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.53399703537153 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (192) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC2A_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-193 |
27328 |
|
PCDH11X |
|
-0.905874588772393 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (193) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SU8686_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-193 |
27328 |
|
PCDH11X |
|
0.961599749706923 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (193) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SU8686_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-193 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.393957918233793 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (193) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SU8686_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-194 |
27328 |
|
PCDH11X |
|
-0.266275332437335 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (194) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1417_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-194 |
27328 |
|
PCDH11X |
|
2.72184328360749 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (194) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1417_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-194 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.61449593231982 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (194) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1417_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-195 |
27328 |
|
PCDH11X |
|
0.906863972200712 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (195) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1783_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-195 |
27328 |
|
PCDH11X |
|
0.265046957553024 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (195) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1783_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-195 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.930084193334706 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (195) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1783_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-196 |
27328 |
|
PCDH11X |
|
0.0369355930940533 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (196) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW480_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-196 |
27328 |
|
PCDH11X |
|
1.45742824272486 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (196) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW480_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-196 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-1.09816726923477 |
Decreased shRNA abundance (Z-score < -2) |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (196) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW480_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-197 |
27328 |
|
PCDH11X |
|
-0.174440872664526 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (197) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW48_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-197 |
27328 |
|
PCDH11X |
|
-1.66612705484645 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (197) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW48_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-197 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.396374399818847 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (197) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW48_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-198 |
27328 |
|
PCDH11X |
|
1.45540956006362 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (198) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
T98G_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-198 |
27328 |
|
PCDH11X |
|
-0.0486655158319521 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (198) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
T98G_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-198 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.118219596742177 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (198) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
T98G_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-199 |
27328 |
|
PCDH11X |
|
0.466538523889447 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (199) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TC71_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-199 |
27328 |
|
PCDH11X |
|
-0.162233557351535 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (199) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TC71_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-199 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.406683960310896 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (199) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TC71_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-2 |
27328 |
|
PCDH11X |
|
1.47222868615934 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (2) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
697_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-2 |
27328 |
|
PCDH11X |
|
-1.25288776110391 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (2) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
697_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-2 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.643684084510794 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (2) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
697_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-20 |
27328 |
|
PCDH11X |
|
1.45735542560381 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (20) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CADOES1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-20 |
27328 |
|
PCDH11X |
|
0.463559382119297 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (20) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CADOES1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-20 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.208910890653577 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (20) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CADOES1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-200 |
27328 |
|
PCDH11X |
|
2.11250799922885 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (200) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TCCSUP_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-200 |
27328 |
|
PCDH11X |
|
-0.671051994602163 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (200) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TCCSUP_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-200 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0784541774929799 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (200) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TCCSUP_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-201 |
27328 |
|
PCDH11X |
|
-1.25867471482709 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (201) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE10_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-201 |
27328 |
|
PCDH11X |
|
-0.635433674490103 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (201) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE10_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-201 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.235721340191049 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (201) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE10_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-202 |
27328 |
|
PCDH11X |
|
-0.494213914517526 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (202) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE15_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-202 |
27328 |
|
PCDH11X |
|
-0.902390487366022 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (202) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE15_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-202 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.682952739271545 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (202) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE15_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-203 |
27328 |
|
PCDH11X |
|
-0.465106185433293 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (203) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE9_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-203 |
27328 |
|
PCDH11X |
|
0.0977852505389506 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (203) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE9_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-203 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.21344006281609 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (203) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE9_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-204 |
27328 |
|
PCDH11X |
|
1.85122944841356 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (204) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-204 |
27328 |
|
PCDH11X |
|
-0.96168143290334 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (204) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-204 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.206373225521446 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (204) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-205 |
27328 |
|
PCDH11X |
|
0.530810404713779 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (205) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV112D_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-205 |
27328 |
|
PCDH11X |
|
0.242831455488051 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (205) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV112D_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-205 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.283626724547374 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (205) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV112D_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-206 |
27328 |
|
PCDH11X |
|
-0.904015179872329 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (206) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV21G_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-206 |
27328 |
|
PCDH11X |
|
0.296099880132839 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (206) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV21G_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-206 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.355252601837692 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (206) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV21G_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-207 |
27328 |
|
PCDH11X |
|
-1.0081275878156 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (207) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TT_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-207 |
27328 |
|
PCDH11X |
|
0.265437535341674 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (207) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TT_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-207 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.88914635688882 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (207) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TT_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-208 |
27328 |
|
PCDH11X |
|
1.59823383370743 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (208) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TYKNU_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-208 |
27328 |
|
PCDH11X |
|
1.05712880642933 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (208) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TYKNU_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-208 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.268335778255377 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (208) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TYKNU_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-209 |
27328 |
|
PCDH11X |
|
-0.282548812917401 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (209) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U178_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-209 |
27328 |
|
PCDH11X |
|
-0.759666112927052 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (209) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U178_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-209 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.28709977834532 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (209) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U178_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-21 |
27328 |
|
PCDH11X |
|
0.0674530695109558 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (21) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL120_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-21 |
27328 |
|
PCDH11X |
|
0.255202556222263 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (21) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL120_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-21 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.4633064096228 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (21) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL120_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-210 |
27328 |
|
PCDH11X |
|
-0.201589993202742 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (210) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U251MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-210 |
27328 |
|
PCDH11X |
|
-0.0769825920817924 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (210) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U251MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-210 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.118182825427342 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (210) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U251MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-211 |
27328 |
|
PCDH11X |
|
1.98591234816917 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (211) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U343_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-211 |
27328 |
|
PCDH11X |
|
-0.40223285984253 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (211) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U343_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-211 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.0499754346411049 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (211) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U343_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-212 |
27328 |
|
PCDH11X |
|
-0.29259826881887 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (212) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U87MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-212 |
27328 |
|
PCDH11X |
|
-0.746585357570498 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (212) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U87MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-212 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.148627516709153 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (212) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U87MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-213 |
27328 |
|
PCDH11X |
|
0.304310672163266 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (213) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
UOK101_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-213 |
27328 |
|
PCDH11X |
|
0.640584853224192 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (213) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
UOK101_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-213 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.542502924897964 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (213) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
UOK101_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-214 |
27328 |
|
PCDH11X |
|
0.660878038580804 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (214) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
VCAP_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-214 |
27328 |
|
PCDH11X |
|
1.99037416152431 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (214) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
VCAP_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-214 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0849261008616397 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (214) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
VCAP_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-215 |
27328 |
|
PCDH11X |
|
0.144612919658737 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (215) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
YKG1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-215 |
27328 |
|
PCDH11X |
|
1.51003008436188 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (215) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
YKG1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-215 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.425103877520287 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (215) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
YKG1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-216 |
27328 |
|
PCDH11X |
|
-0.127366681770529 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (216) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ZR7530_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-216 |
27328 |
|
PCDH11X |
|
-0.0986846965400666 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (216) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ZR7530_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-216 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.654156442846409 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (216) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ZR7530_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-22 |
27328 |
|
PCDH11X |
|
-0.618138096421564 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (22) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL51_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-22 |
27328 |
|
PCDH11X |
|
1.28326491023136 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (22) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL51_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-22 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.254929865172774 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (22) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL51_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-23 |
27328 |
|
PCDH11X |
|
0.25509701758798 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (23) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CALU1_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-23 |
27328 |
|
PCDH11X |
|
-0.407142733585537 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (23) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CALU1_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-23 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.0880999298389314 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (23) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CALU1_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-24 |
27328 |
|
PCDH11X |
|
-0.668815345224786 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (24) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-24 |
27328 |
|
PCDH11X |
|
0.343665632312054 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (24) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-24 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.658718397138953 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (24) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-25 |
27328 |
|
PCDH11X |
|
1.41748273661589 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (25) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-25 |
27328 |
|
PCDH11X |
|
0.782368230732235 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (25) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-25 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.633502635582707 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (25) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-26 |
27328 |
|
PCDH11X |
|
1.1834616202027 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (26) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-26 |
27328 |
|
PCDH11X |
|
-0.811850601534529 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (26) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-26 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.569805894334934 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (26) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-27 |
27328 |
|
PCDH11X |
|
1.26554030775555 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (27) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CFPAC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-27 |
27328 |
|
PCDH11X |
|
-0.0806689452570342 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (27) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CFPAC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-27 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.744185641889173 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (27) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CFPAC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-28 |
27328 |
|
PCDH11X |
|
-0.3991988618159 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (28) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CH157MN_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-28 |
27328 |
|
PCDH11X |
|
-0.012896670096028 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (28) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CH157MN_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-28 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.995815930754651 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (28) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CH157MN_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-29 |
27328 |
|
PCDH11X |
|
-1.31165075956949 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (29) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO205_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-29 |
27328 |
|
PCDH11X |
|
1.41051020074647 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (29) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO205_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-29 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.404496623906926 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (29) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO205_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-3 |
27328 |
|
PCDH11X |
|
0.301860861102351 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (3) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
786O_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-3 |
27328 |
|
PCDH11X |
|
0.0913756263192461 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (3) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
786O_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-3 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.440043203432703 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (3) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
786O_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-30 |
27328 |
|
PCDH11X |
|
-0.593005694049246 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (30) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO704_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-30 |
27328 |
|
PCDH11X |
|
-0.0412066818194415 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (30) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO704_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-30 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.512473299704044 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (30) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO704_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-31 |
27328 |
|
PCDH11X |
|
-1.0121109471865 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (31) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO741_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-31 |
27328 |
|
PCDH11X |
|
-0.237122041821422 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (31) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO741_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-31 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.72184959231097 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (31) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO741_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-32 |
27328 |
|
PCDH11X |
|
0.621234275768283 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (32) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO783_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-32 |
27328 |
|
PCDH11X |
|
-0.109852715734271 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (32) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO783_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-32 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.448793101365309 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (32) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO783_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-33 |
27328 |
|
PCDH11X |
|
-2.24471026277606 |
Decreased shRNA abundance (Z-score < -2) |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (33) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CORL23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-33 |
27328 |
|
PCDH11X |
|
-1.34732610409658 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (33) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CORL23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-33 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.59371293843433 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (33) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CORL23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-34 |
27328 |
|
PCDH11X |
|
-2.01380635883451 |
Decreased shRNA abundance (Z-score < -2) |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (34) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV362_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-34 |
27328 |
|
PCDH11X |
|
0.637945331438433 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (34) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV362_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-34 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.177626701893878 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (34) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV362_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-35 |
27328 |
|
PCDH11X |
|
-0.752349846538501 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (35) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV434_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-35 |
27328 |
|
PCDH11X |
|
0.473942997140075 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (35) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV434_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-35 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.689258382006897 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (35) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV434_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-36 |
27328 |
|
PCDH11X |
|
0.309782109209034 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (36) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV504_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-36 |
27328 |
|
PCDH11X |
|
-0.51969278450279 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (36) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV504_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-36 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.00542890436926063 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (36) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV504_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-37 |
27328 |
|
PCDH11X |
|
-0.28879848288335 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (37) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV644_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-37 |
27328 |
|
PCDH11X |
|
0.0119175956882438 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (37) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV644_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-37 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.773937737889017 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (37) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV644_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-38 |
27328 |
|
PCDH11X |
|
-0.128244709098179 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (38) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DBTRG05MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-38 |
27328 |
|
PCDH11X |
|
-0.18400671450152 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (38) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DBTRG05MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-38 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.638276450107418 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (38) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DBTRG05MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-39 |
27328 |
|
PCDH11X |
|
1.5955733838941 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (39) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DKMG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-39 |
27328 |
|
PCDH11X |
|
-0.514301085253088 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (39) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DKMG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-39 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.21161788787813 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (39) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DKMG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-4 |
27328 |
|
PCDH11X |
|
1.29393973328842 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (4) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A1207_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-4 |
27328 |
|
PCDH11X |
|
-0.137807412798099 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (4) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A1207_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-4 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.382087206626773 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (4) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A1207_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-40 |
27328 |
|
PCDH11X |
|
2.01028093834489 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (40) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DLD1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-40 |
27328 |
|
PCDH11X |
|
1.38216399211718 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (40) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DLD1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-40 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
1.56292482587721 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (40) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DLD1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-41 |
27328 |
|
PCDH11X |
|
-1.10477446568906 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (41) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFE184_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-41 |
27328 |
|
PCDH11X |
|
-0.893621936420373 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (41) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFE184_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-41 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0835883475259458 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (41) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFE184_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-42 |
27328 |
|
PCDH11X |
|
0.947661395145032 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (42) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFM19_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-42 |
27328 |
|
PCDH11X |
|
0.662947558449835 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (42) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFM19_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-42 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.216616285719896 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (42) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFM19_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-43 |
27328 |
|
PCDH11X |
|
0.284055096168648 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (43) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO21_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-43 |
27328 |
|
PCDH11X |
|
2.09507762426418 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (43) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO21_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-43 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.683137051313061 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (43) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO21_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-44 |
27328 |
|
PCDH11X |
|
0.4606571245185 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (44) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO27_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-44 |
27328 |
|
PCDH11X |
|
-0.589019943191915 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (44) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO27_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-44 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0608928839680888 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (44) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO27_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-45 |
27328 |
|
PCDH11X |
|
-0.0497903852921846 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (45) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EW8_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-45 |
27328 |
|
PCDH11X |
|
0.0692784555603094 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (45) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EW8_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-45 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.038314528251279 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (45) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EW8_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-46 |
27328 |
|
PCDH11X |
|
2.41862844231563 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (46) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EWS502_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-46 |
27328 |
|
PCDH11X |
|
1.07930716278789 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (46) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EWS502_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-46 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.402124394529363 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (46) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EWS502_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-47 |
27328 |
|
PCDH11X |
|
0.419540452975672 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (47) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-47 |
27328 |
|
PCDH11X |
|
-1.90490243106487 |
Decreased shRNA abundance (Z-score < -2) |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (47) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-47 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.375983947515438 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (47) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-48 |
27328 |
|
PCDH11X |
|
0.162340904702648 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (48) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GB1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-48 |
27328 |
|
PCDH11X |
|
-0.875545337139822 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (48) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GB1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-48 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.0429608583320563 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (48) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GB1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-49 |
27328 |
|
PCDH11X |
|
-1.68569063380235 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (49) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GP2D_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-49 |
27328 |
|
PCDH11X |
|
0.622397175130323 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (49) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GP2D_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-49 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.0906522258882748 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (49) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GP2D_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-5 |
27328 |
|
PCDH11X |
|
-0.487178887528587 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (5) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-5 |
27328 |
|
PCDH11X |
|
-0.19354624368014 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (5) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-5 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.022310895763435 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (5) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-50 |
27328 |
|
PCDH11X |
|
-0.735145883496007 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (50) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1187_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-50 |
27328 |
|
PCDH11X |
|
2.10392358172008 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (50) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1187_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-50 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.302513985378188 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (50) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1187_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-51 |
27328 |
|
PCDH11X |
|
-0.847441109265078 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (51) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1395_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-51 |
27328 |
|
PCDH11X |
|
-0.288356583974598 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (51) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1395_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-51 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.876604600610101 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (51) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1395_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-52 |
27328 |
|
PCDH11X |
|
1.42304786753184 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (52) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1954_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-52 |
27328 |
|
PCDH11X |
|
-0.0822594133682905 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (52) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1954_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-52 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.516141454682991 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (52) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1954_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-53 |
27328 |
|
PCDH11X |
|
0.0923453504025196 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (53) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2218_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-53 |
27328 |
|
PCDH11X |
|
-0.561649625023858 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (53) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2218_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-53 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.346015308874609 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (53) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2218_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-54 |
27328 |
|
PCDH11X |
|
1.28809167878237 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (54) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2814_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-54 |
27328 |
|
PCDH11X |
|
0.128384070071241 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (54) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2814_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-54 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.894559451333373 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (54) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2814_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-55 |
27328 |
|
PCDH11X |
|
0.695026641282261 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (55) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC364_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-55 |
27328 |
|
PCDH11X |
|
3.70633560856115 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (55) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC364_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-55 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.153006540573055 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (55) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC364_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-56 |
27328 |
|
PCDH11X |
|
1.07355496481685 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (56) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC44_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-56 |
27328 |
|
PCDH11X |
|
-0.224685230296537 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (56) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC44_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-56 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.29161510975151 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (56) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC44_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-57 |
27328 |
|
PCDH11X |
|
1.33205893425011 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (57) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC70_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-57 |
27328 |
|
PCDH11X |
|
0.870346426741595 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (57) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC70_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-57 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.466218651619279 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (57) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC70_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-58 |
27328 |
|
PCDH11X |
|
0.451902679799562 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (58) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827GR5_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-58 |
27328 |
|
PCDH11X |
|
-0.199204793565384 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (58) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827GR5_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-58 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.208639942340207 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (58) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827GR5_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-59 |
27328 |
|
PCDH11X |
|
-0.412695358826472 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (59) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-59 |
27328 |
|
PCDH11X |
|
-0.631441452111439 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (59) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-59 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.358110020236502 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (59) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-6 |
27328 |
|
PCDH11X |
|
0.508216754636781 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (6) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A204_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-6 |
27328 |
|
PCDH11X |
|
0.44902190583326 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (6) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A204_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-6 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.487432015332192 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (6) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A204_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-60 |
27328 |
|
PCDH11X |
|
-0.818072511872076 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (60) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCT116_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-60 |
27328 |
|
PCDH11X |
|
-0.465287914512345 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (60) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCT116_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-60 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.184004381563489 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (60) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCT116_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-61 |
27328 |
|
PCDH11X |
|
-0.927068461182041 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (61) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEC1A_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-61 |
27328 |
|
PCDH11X |
|
0.276452955427143 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (61) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEC1A_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-61 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.419950981892257 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (61) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEC1A_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-62 |
27328 |
|
PCDH11X |
|
-0.767985777226339 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (62) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEYA8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-62 |
27328 |
|
PCDH11X |
|
-1.66624397040566 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (62) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEYA8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-62 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.23335024518747 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (62) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEYA8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-63 |
27328 |
|
PCDH11X |
|
0.887180150348558 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (63) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-63 |
27328 |
|
PCDH11X |
|
1.56702359422244 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (63) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-63 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.460639872023421 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (63) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-64 |
27328 |
|
PCDH11X |
|
-0.32200224630995 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (64) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HLF_LIVER |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-64 |
27328 |
|
PCDH11X |
|
-1.03968662090168 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (64) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HLF_LIVER |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-64 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.291612961084658 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (64) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HLF_LIVER |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-65 |
27328 |
|
PCDH11X |
|
1.43225594164232 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (65) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HNT34_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-65 |
27328 |
|
PCDH11X |
|
-0.68555986455363 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (65) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HNT34_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-65 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0755556757239466 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (65) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HNT34_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-66 |
27328 |
|
PCDH11X |
|
0.000385635820810519 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (66) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAC_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-66 |
27328 |
|
PCDH11X |
|
0.454291974574424 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (66) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAC_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-66 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.668984618148472 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (66) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAC_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-67 |
27328 |
|
PCDH11X |
|
-0.446937530103872 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (67) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAFII_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-67 |
27328 |
|
PCDH11X |
|
0.159644408128433 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (67) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAFII_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-67 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
1.16059625460416 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (67) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAFII_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-68 |
27328 |
|
PCDH11X |
|
0.0338880123234675 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (68) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS683_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-68 |
27328 |
|
PCDH11X |
|
-0.155981749273168 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (68) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS683_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-68 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.914707391556603 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (68) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS683_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-69 |
27328 |
|
PCDH11X |
|
0.230185870461228 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (69) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS766T_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-69 |
27328 |
|
PCDH11X |
|
-0.504184978155199 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (69) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS766T_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-69 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.553119087208443 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (69) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS766T_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-7 |
27328 |
|
PCDH11X |
|
-1.06407503812642 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (7) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A2058_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-7 |
27328 |
|
PCDH11X |
|
0.925087577597299 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (7) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A2058_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-7 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.627823773047695 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (7) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A2058_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-70 |
27328 |
|
PCDH11X |
|
-1.19713187655737 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (70) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS944T_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-70 |
27328 |
|
PCDH11X |
|
-0.930179019534626 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (70) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS944T_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-70 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.666864683075583 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (70) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS944T_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-71 |
27328 |
|
PCDH11X |
|
-0.0423562907390683 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (71) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT1197_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-71 |
27328 |
|
PCDH11X |
|
0.800466098901845 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (71) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT1197_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-71 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.12713890691039 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (71) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT1197_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-72 |
27328 |
|
PCDH11X |
|
-0.291689763743604 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (72) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT29_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-72 |
27328 |
|
PCDH11X |
|
0.645244067934892 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (72) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT29_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-72 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.204286800210616 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (72) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT29_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-73 |
27328 |
|
PCDH11X |
|
-0.00100009057259608 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (73) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT55_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-73 |
27328 |
|
PCDH11X |
|
1.63173484623374 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (73) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT55_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-73 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.328227264449958 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (73) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT55_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-74 |
27328 |
|
PCDH11X |
|
-1.08685250543863 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (74) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUG1N_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-74 |
27328 |
|
PCDH11X |
|
0.823358883018814 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (74) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUG1N_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-74 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.551988653207391 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (74) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUG1N_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-75 |
27328 |
|
PCDH11X |
|
-0.849981683098787 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (75) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUTU80_SMALL_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-75 |
27328 |
|
PCDH11X |
|
-0.644651869667069 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (75) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUTU80_SMALL_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-75 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.302125541310365 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (75) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUTU80_SMALL_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-76 |
27328 |
|
PCDH11X |
|
1.46743410939547 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (76) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGR39_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-76 |
27328 |
|
PCDH11X |
|
2.39242038641849 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (76) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGR39_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-76 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.179066893244985 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (76) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGR39_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-77 |
27328 |
|
PCDH11X |
|
-0.521485468572353 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (77) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGROV1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-77 |
27328 |
|
PCDH11X |
|
1.28254617810773 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (77) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGROV1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-77 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.299677165065162 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (77) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGROV1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-78 |
27328 |
|
PCDH11X |
|
-0.265788618252531 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (78) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IOMMLEE_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-78 |
27328 |
|
PCDH11X |
|
-0.59433958396384 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (78) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IOMMLEE_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-78 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-1.10662169301529 |
Decreased shRNA abundance (Z-score < -2) |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (78) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IOMMLEE_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-79 |
27328 |
|
PCDH11X |
|
-0.435935506677979 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (79) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHESOAD1_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-79 |
27328 |
|
PCDH11X |
|
0.422305143302947 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (79) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHESOAD1_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-79 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.442712502429228 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (79) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHESOAD1_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-8 |
27328 |
|
PCDH11X |
|
-0.0136478610845226 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (8) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A549_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-8 |
27328 |
|
PCDH11X |
|
0.200689421232697 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (8) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A549_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-8 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.273366554576734 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (8) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A549_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-80 |
27328 |
|
PCDH11X |
|
-0.798113982505392 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (80) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOC5_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-80 |
27328 |
|
PCDH11X |
|
0.373394681711899 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (80) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOC5_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-80 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0733436439274834 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (80) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOC5_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-81 |
27328 |
|
PCDH11X |
|
0.418907405405068 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (81) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOM1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-81 |
27328 |
|
PCDH11X |
|
0.993604930726039 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (81) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOM1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-81 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.915703070258623 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (81) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOM1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-82 |
27328 |
|
PCDH11X |
|
-0.594076916717048 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (82) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JJN3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-82 |
27328 |
|
PCDH11X |
|
-1.04923676372016 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (82) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JJN3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-82 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.237087623337963 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (82) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JJN3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-83 |
27328 |
|
PCDH11X |
|
2.42085148821099 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (83) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-83 |
27328 |
|
PCDH11X |
|
-0.189890809864411 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (83) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-83 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.35460795107534 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (83) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-84 |
27328 |
|
PCDH11X |
|
0.332779644770599 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (84) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KALS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-84 |
27328 |
|
PCDH11X |
|
1.59180477412562 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (84) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KALS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-84 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.811727333947009 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (84) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KALS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-85 |
27328 |
|
PCDH11X |
|
1.89219681028106 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (85) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-85 |
27328 |
|
PCDH11X |
|
0.123280090828925 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (85) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-85 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.551714607181084 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (85) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-86 |
27328 |
|
PCDH11X |
|
-1.85985113466648 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (86) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KM12_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-86 |
27328 |
|
PCDH11X |
|
-0.170938953256076 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (86) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KM12_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-86 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.0146653353651035 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (86) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KM12_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-87 |
27328 |
|
PCDH11X |
|
-0.457925574881169 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (87) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KMS12BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-87 |
27328 |
|
PCDH11X |
|
0.199882290545834 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (87) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KMS12BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-87 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.586834030405889 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (87) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KMS12BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-88 |
27328 |
|
PCDH11X |
|
0.1427587777404 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (88) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS60_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-88 |
27328 |
|
PCDH11X |
|
0.634231475904174 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (88) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS60_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-88 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.393526985330559 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (88) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS60_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-89 |
27328 |
|
PCDH11X |
|
0.425376948071428 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (89) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS81_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-89 |
27328 |
|
PCDH11X |
|
0.7891335162017 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (89) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS81_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-89 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.732981846201844 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (89) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS81_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-9 |
27328 |
|
PCDH11X |
|
-0.0375757250986471 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (9) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A673_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-9 |
27328 |
|
PCDH11X |
|
1.02543834185941 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (9) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A673_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-9 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.403756823134052 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (9) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A673_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-90 |
27328 |
|
PCDH11X |
|
-0.0839582684957498 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (90) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP1NL_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-90 |
27328 |
|
PCDH11X |
|
0.256540058779055 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (90) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP1NL_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-90 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.248011077853307 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (90) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP1NL_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-91 |
27328 |
|
PCDH11X |
|
-0.204652890994885 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (91) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-91 |
27328 |
|
PCDH11X |
|
1.07023469930784 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (91) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-91 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.651460347233487 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (91) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-92 |
27328 |
|
PCDH11X |
|
-0.186901788817149 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (92) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP4_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-92 |
27328 |
|
PCDH11X |
|
0.515993679205691 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (92) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP4_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-92 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.026453354259387 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (92) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP4_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-93 |
27328 |
|
PCDH11X |
|
-0.955366499166522 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (93) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KURAMOCHI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-93 |
27328 |
|
PCDH11X |
|
0.510098724130861 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (93) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KURAMOCHI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-93 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.0452503565431877 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (93) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KURAMOCHI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-94 |
27328 |
|
PCDH11X |
|
-0.186357045106765 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (94) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE150_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-94 |
27328 |
|
PCDH11X |
|
0.0773366826374029 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (94) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE150_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-94 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-1.04494305781739 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (94) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE150_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-95 |
27328 |
|
PCDH11X |
|
-1.96020243167774 |
Decreased shRNA abundance (Z-score < -2) |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (95) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE30_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-95 |
27328 |
|
PCDH11X |
|
0.434204151921455 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (95) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE30_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-95 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.582612495527741 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (95) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE30_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-96 |
27328 |
|
PCDH11X |
|
-0.495955089095642 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (96) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE450_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-96 |
27328 |
|
PCDH11X |
|
0.224839613832429 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (96) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE450_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-96 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
0.0317417309801885 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (96) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE450_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-97 |
27328 |
|
PCDH11X |
|
-0.771481009590228 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (97) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE510_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-97 |
27328 |
|
PCDH11X |
|
-0.541375017059309 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (97) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE510_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-97 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.267744686279087 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (97) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE510_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-98 |
27328 |
|
PCDH11X |
|
0.563014613287124 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (98) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L33_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-98 |
27328 |
|
PCDH11X |
|
2.20468948992219 |
Increased shRNA abundance (Z-score > 2) |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (98) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L33_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-98 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.47609096983118 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (98) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L33_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-99 |
27328 |
|
PCDH11X |
|
-0.49931439876853 |
none |
|
|
PCDH11X_1_110000000010 |
Context-specific genetic dependencies (99) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L363_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-99 |
27328 |
|
PCDH11X |
|
0.155709348082166 |
none |
|
|
PCDH11X_2_001010001100 |
Context-specific genetic dependencies (99) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L363_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-99 |
27328 |
|
PCDH11X |
TRCN0000056354, TRCN0000056355 |
-0.0741565378249665 |
none |
|
|
PCDH11X_3_000101110001 |
Context-specific genetic dependencies (99) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L363_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
|
27328 |
27328 |
PCDH11X |
|
-0.1 |
none |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GR00376-A-1 |
27328 |
27328 |
PCDH11X |
|
0.352905352 |
none |
|
|
|
Mitigators of SS1P-induced immunotoxicity |
Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity |
Pasetto et al. |
2015 |
25713356 |
Cell line |
KB cells |
Viability |
Luminescence |
Ambion Silencer Select Version 4 |
Genome-wide |
siRNA |
RSA P-value |
<0.001 |
SS1P was applied in a "high dose", ≈EC90, 13 ng/ml. Cutoff was derived from data submitted to Pubchem (ID 1117281). Reagent sequences but no ID |
GR00376-A-2 |
27328 |
27328 |
PCDH11X |
|
0.267309549 |
none |
|
|
|
Sensitizers of SS1P-induced immunotoxicity |
Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity |
Pasetto et al. |
2015 |
25713356 |
Cell line |
KB cells |
Viability |
Luminescence |
Ambion Silencer Select Version 4 |
Genome-wide |
siRNA |
RSA P-value |
<0.001 |
SS1P was applied in a "low dose", ≈EC30, 3 ng/ml. Cutoff was derived from data submitted to PubChem (ID 1117281). Reagent sequences but no ID |
GR00378-A |
27328 |
|
PCDH11X |
|
-1.150291497 |
none |
|
|
|
Poliovirus vaccine production |
Engineering Enhanced Vaccine Cell Lines To Eradicate Vaccine-Preventable Diseases: the Polio End Game |
van der Sanden et al. |
2015 |
26581994 |
Cell line |
HEp-2C |
Infection with Attenuated Poliovirus |
ELISA |
Dharmacon |
Genome-wide |
siRNA |
Z-score |
> |
For infection, a single lot of the attenuated Sabin type 2 poliovirus was used for the screen. Gene IDs were not provided, only the gene name/symbol |
|
27328 |
NM_014522 |
PCDH11X |
|
64.763 |
none |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GR00386-A-1 |
27328 |
27328 |
PCDH11X |
|
62.1532357276646 |
Decreased viability |
|
|
|
NOD2 stimulation by MDP |
A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-κB (NF-κB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion. |
Warner et al. |
2014 |
25170077 |
Cell line |
HEK293 stably expressing NOD2 |
Viability |
Luminescence |
Dharmacon |
Genome-wide |
siRNA |
Percentage growth |
Decreased: <70, increased: >120 |
Reagent IDs not provided |
GR00386-A-2 |
27328 |
27328 |
PCDH11X |
|
75.8 |
Decreased IL-8 secretion |
|
|
|
MDP-induced IL-8 secretion |
A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-κB (NF-κB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion. |
Warner et al. |
2014 |
25170077 |
Cell line |
HEK293 stably expressing NOD2 |
IL-8 secretion |
ELISA |
Dharmacon |
Genome-wide |
siRNA |
Percent inhibition of IL-8 secretion |
Increased: <-300, Decreased: >60 |
Concentration of IL-8 was measured from cell supernatants by sandwich ELISA. IL-8 values (pg/ml) were normalized to IL-8 secreted in cells treated with RIPK2-specific siRNA (100% inhibition) and non-targeting siRNA (0% inhibition). Secondary validating screen assessed 554 genes whose silencing affected MDP-induced IL-8 secretion in the primary screen. Final validated IL-8 regulators (positive or negative) are listed in the comments column. Reagent IDs not provided |