| GR00018-A-0 |
6218 |
|
RPS17 |
v2HS_232330 |
-0.85 (0.29) |
Synthetic lethal with Ras |
|
no |
|
Synthetic lethal interaction with Ras |
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. |
Luo et al. |
2009 |
19490893 |
Cell line |
DLD-1 |
Synthetic lethal interaction with Ras |
Micoarray hybridization |
shRNA-mir (G. Hannon) |
|
shRNA |
Log2 diff MUT-WT (and P-value) |
-0.7 (0.3) |
|
GR00053-A |
6218 |
NM_001021 |
RPS17 |
np |
sp |
none |
|
no |
|
Genome stability |
A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability. |
Paulsen et al. |
2009 |
19647519 |
Cell line |
HeLa |
gamma-H2AX phosphorylation and DNA content |
Fluorescence |
siARRAY human genome siRNA library |
Genome-wide |
siRNA |
p-value |
Complex criteria |
Confidence groupings from 4 to 1 (highest level of confidence in group 4) |
GR00054-A |
6218 |
NM_001021 |
RPS17 |
np |
1.019 |
none |
|
no |
|
Combinatorial effect with paclitaxel |
Synthetic lethal screen identification of chemosensitizer loci in cancer cells. |
Whitehurst et al. |
2007 |
17429401 |
Cell line |
NCI-H1155 |
Viability (synthetic lethal) |
ATP level |
# G-005000-01 |
Genome-wide |
siRNA |
Paclitaxel/control ratio |
Complex criteria |
Additional information about 87 high-confidence hits |
GR00056-A |
6218 |
NM_001021 |
RPS17 |
np |
0.997 |
none |
|
no |
|
Melanogenesis |
Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells. |
Ganesan et al. |
2008 |
19057677 |
Cell line |
MNT-1 |
Melanin protein expression and viability |
Absorbance and luminescence |
rp |
Genome-wide |
siRNA |
Normalized absorbance ratio |
> 2 standard deviations below mean |
Additional information about a secondary screen (retest to determine false-positive rate) |
GR00057-A-1 |
6218 |
NM_001021 |
RPS17 |
M-011152-00 |
-0.93 |
none |
|
no |
|
Wnt/beta-catenin pathway regulation (1) |
A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer. |
Tang et al. |
2008 |
18621708 |
Cell line |
HeLa |
Wnt pathway reporter |
Luminescence |
Human siArray siRNA library |
Genome-wide |
siRNA |
Z-score |
> 4 |
Screen without Wnt3A stimulation. Additional information about secondary screens (Dharmacon and Qiagen libraries). |
GR00057-A-2 |
6218 |
NM_001021 |
RPS17 |
M-011152-00 |
sp |
none |
|
no |
|
Wnt/beta-catenin pathway regulation (2) |
A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer. |
Tang et al. |
2008 |
18621708 |
Cell line |
HeLa |
Wnt pathway reporter |
Luminescence |
Human siArray siRNA library |
Genome-wide |
siRNA |
Complex, SP |
Complex criteria |
Screen with Wnt3A stimulation. Additional information about secondary screens (Dharmacon and Qiagen libraries). |
GR00098-A-1 |
6218 |
ENSG00000184779 |
RPS17 |
ENSG00000184779 |
sp |
Increased S DNA content |
|
yes |
S arrest, validated with resynthesized esiRNA |
Cell division (1) |
Genome-scale RNAi profiling of cell division in human tissue culture cells. |
Kittler et al. |
2007 |
17994010 |
Cell line |
HeLa |
Cell number and DNA content |
Laser scanning cytometry |
rp |
Genome-wide |
esiRNA |
Complex, sp |
Complex criteria |
|
GR00098-A-1 |
6218 |
ENSG00000197575 |
RPS17 |
ENSG00000197575 |
sp |
none |
|
no |
|
Cell division (1) |
Genome-scale RNAi profiling of cell division in human tissue culture cells. |
Kittler et al. |
2007 |
17994010 |
Cell line |
HeLa |
Cell number and DNA content |
Laser scanning cytometry |
rp |
Genome-wide |
esiRNA |
Complex, sp |
Complex criteria |
|
GR00098-A-1 |
6218 |
ENSG00000182774 |
RPS17 |
ENSG00000182774 |
sp |
Increased S DNA content |
|
no |
|
Cell division (1) |
Genome-scale RNAi profiling of cell division in human tissue culture cells. |
Kittler et al. |
2007 |
17994010 |
Cell line |
HeLa |
Cell number and DNA content |
Laser scanning cytometry |
rp |
Genome-wide |
esiRNA |
Complex, sp |
Complex criteria |
|
GR00098-A-1 |
6218 |
ENSG00000198235 |
RPS17 |
ENSG00000198235 |
sp |
Increased S DNA content |
|
no |
|
Cell division (1) |
Genome-scale RNAi profiling of cell division in human tissue culture cells. |
Kittler et al. |
2007 |
17994010 |
Cell line |
HeLa |
Cell number and DNA content |
Laser scanning cytometry |
rp |
Genome-wide |
esiRNA |
Complex, sp |
Complex criteria |
|
GR00098-A-3 |
6218 |
ENSG00000184779 |
RPS17 |
ENSG00000184779 |
-1.6 |
none |
|
yes |
|
Cell division (3) |
Genome-scale RNAi profiling of cell division in human tissue culture cells. |
Kittler et al. |
2007 |
17994010 |
Cell line |
HeLa |
Histone H3 phosphorylation; alpha-tubulin and pericentrin protein expression |
Fluorescence |
rp |
Selected genes |
esiRNA |
Mitotic index |
> |
|
GR00098-A-4 |
6218 |
ENSG00000184779 |
RPS17 |
ENSG00000184779 |
-4.6 |
none |
|
no |
|
Cell division (4) |
Genome-scale RNAi profiling of cell division in human tissue culture cells. |
Kittler et al. |
2007 |
17994010 |
Cell line |
HeLa |
Cell size (forward scatter) |
Flow cytometry |
rp |
Selected genes |
esiRNA |
Cell size |
> |
|
GR00106-A-0 |
6218 |
|
RPS17 |
np |
12 |
Decreased viability |
|
no |
|
Cell viability |
Highly parallel identification of essential genes in cancer cells. |
Luo et al. |
2008 |
19091943 |
Cell line |
12 cancer cell lines |
Cell viability |
Micoarray hybridization |
TRC shRNA library |
|
shRNA |
Essentiality |
> |
|
GR00151-A-1 |
6218 |
ENSG00000182774 |
AC010724.6-6 |
np |
-0.493 |
none |
|
no |
|
Homologous recombination DNA double-strand break repair (HR-DSBR) (1) |
A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia. |
Słabicki et al. |
2010 |
20613862 |
Cell line |
HeLa |
(HR-DSBR) DR-GFP reporter |
Flow cytometry |
Custom-made |
Genome-wide |
esiRNA |
Z-score |
< -2 OR > 2 |
|
GR00180-A-1 |
6218 |
6218 |
RPS17 |
PL-50050 |
0.796 |
none |
|
no |
|
Hepatitis C virus replication (1) |
A functional genomic screen identifies cellular cofactors of hepatitis C virus replication. |
Tai et al. |
2009 |
19286138 |
Cell line |
Huh7/Rep-Feo |
HCV replicon RNA copy number |
Luminescence |
siARRAY Human Genome siRNA Library |
Genome-wide |
siRNA |
q-value |
Complex criteria |
|
GR00184-A-1 |
6218 |
NM_001021 |
RPS17 |
M-011152-00 |
0.0891854859000998 |
none |
|
no |
|
Self-renewal and pluripotency in human embryonic stem cells (1) |
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. |
Chia et al. |
2010 |
20953172 |
Cell line |
hESC H1 |
POU5F1 protein expression |
Fluorescence |
SMARTpool siRNA library |
Genome-wide |
siRNA |
Z-score |
< -2 |
|
GR00196-A-1 |
6218 |
ENSG00000182774 |
|
np |
sp |
Decreased viability of wild-type and TP53 knockout cells |
|
no |
viability Z-score < -1.5 |
TP53 interactions (1) |
A systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly. |
Krastev et al. |
2011 |
21642980 |
Cell line |
HCT116 ( wildtype and TP53 knockout) |
TP53 protein expression and viability |
Fluorescence |
rp |
Genome-wide |
esiRNA |
Complex, sp |
Complex criteria |
|
GR00197-A-1 |
6218 |
6218 |
RPS17 |
M-011152-00 |
-1.546364383 |
none |
|
no |
|
Human papillomavirus oncogene expression regulation (1) |
Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression. |
Smith et al. |
2010 |
20133580 |
Cell line |
C33A/BE2/18LCR c4 |
HPV18 LCR reporter activity |
Luminescence |
Human siGENOME SMARTpool library |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Phenotype strength according to Z-scores: weak: 2 - 3; moderate: 3 - 5; strong: > 5 |
GR00209-A-1 |
6218 |
NM_001021 |
RPS17 |
np |
0.63 |
Nucleolar pre-40S maturation defects |
|
yes |
10 nM siRNA; ratio nucleoplasmic/total hit classified cells: 0.3165205 |
Ribosome biogenesis (1) |
A protein inventory of human ribosome biogenesis reveals an essential function of exportin 5 in 60S subunit export. |
Wild et al. |
2010 |
21048991 |
Cell line |
HeLa |
Rps2 protein expression |
Fluorescence |
np |
Selected genes |
siRNA |
Average relative rank from > |
> 0.2 |
|
GR00209-A-2 |
6218 |
NM_001021 |
RPS17 |
np |
sp |
Cytoplasmic 40S maturation defects |
|
yes |
|
Ribosome biogenesis (2) |
A protein inventory of human ribosome biogenesis reveals an essential function of exportin 5 in 60S subunit export. |
Wild et al. |
2010 |
21048991 |
Cell line |
HeLa |
Enp1 protein expression |
Fluorescence |
np |
Selected genes |
siRNA |
Complex, sp |
Complex criteria |
|
GR00209-A-3 |
6218 |
NM_001021 |
RPS17 |
np |
np |
none |
|
yes |
|
Ribosome biogenesis (3) |
A protein inventory of human ribosome biogenesis reveals an essential function of exportin 5 in 60S subunit export. |
Wild et al. |
2010 |
21048991 |
Cell line |
HeLa |
Rpl29 protein expression |
Fluorescence |
np |
Selected genes |
siRNA |
Average relative rank from > |
> 0.25 |
|
GR00232-A-1 |
6218 |
NM_001021 |
RPS17 |
v2HS_140458 |
-1.12857137166667 |
Increased ionizing radiation sensitivity |
|
no |
|
DNA damage regulation after ionizing radiation (1) |
A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability. |
Hurov et al. |
2010 |
20810650 |
Cell line |
U2OS |
Ionizing radiation sensitivity |
Fluorescence |
pSMP |
Genome-wide |
shRNA |
log2 mean ratio |
< -1 OR > 1 |
The shRNA library is in a MSCV-PURO-based vector (MSCV-PM; Open Biosystems nomenclature is pSMP). The shRNAs with the “V3LHS†identifier were subcloned into the MSCV-PM vector from the pGIPZ vector. Additional information about a secondary screen in H460 cells. |
|
6218 |
|
RPS17 |
np |
np |
Decreased viability in ovarian lineage |
|
no |
ovarian: no filter, KS |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GR00236-A-1 |
6218 |
6218 |
RPS17 |
M-011152-00 |
1.47526607742037 |
none |
|
no |
|
Homologous recombination DNA double-strand break repair (HR-DSBR) (1) |
A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. |
Adamson et al. |
2012 |
22344029 |
Cell line |
DR-U2OS |
(HR-DSBR) DR-GFP reporter and DNA content |
Fluorescence |
Human siGENOME siRNA (G-005000-05) |
Genome-wide |
siRNA |
Relative HR ratio |
< ~0.4 OR > 1.88 |
Cutoff values correspond 2 standard deviations from the screen-wide mean |
GR00240-S-1 |
6218 |
NM_001021 |
RPS17 |
M-011152-00 |
3.68 |
none |
|
yes |
|
TRAIL-induced apoptosis (1) |
A synthetic lethal screen identifies FAT1 as an antagonist of caspase-8 in extrinsic apoptosis. |
Kranz and Boutros |
2014 |
24442637 |
Cell line |
U251MG |
Viability |
Luminescence |
SMART-pool siRNA |
Genome-wide |
siRNA |
Z-score |
> 4 |
Author-submitted data |
GR00240-S-2 |
6218 |
NM_001021 |
RPS17 |
M-011152-00 |
0.97 |
none |
|
no |
Z-score 3.86 |
TRAIL-induced apoptosis (2) |
A synthetic lethal screen identifies FAT1 as an antagonist of caspase-8 in extrinsic apoptosis. |
Kranz and Boutros |
2014 |
24442637 |
Cell line |
U251MG |
Viability (synthetic lethal) |
Luminescence |
SMART-pool siRNA |
Genome-wide |
siRNA |
Differential score |
> 3.6 AND viability Z-score < 4 |
Author-submitted data. Z-scores from viability screen (1) are considered in score interpretation for this screen. |
GR00242-A-1 |
6218 |
NM_001021 |
RPS17 |
np |
sp |
none |
|
no |
|
Selective autophagy regulation (1) |
Image-based genome-wide siRNA screen identifies selective autophagy factors. |
Orvedahl et al. |
2011 |
22020285 |
Cell line |
HeLa/GFP-LC3 |
Sindbis virus (SIN) capsid SIN-mCherry.capsid and autophagosome GFP–LC3 protein expression |
Fluorescence |
siGenome |
Genome-wide |
siRNA |
Z-score |
Complex criteria |
|
GR00247-A-1 |
6218 |
|
RPS17 |
np |
sp |
none |
|
|
rank: 301; excluded (false positive) |
Regulation of FOXO1 nuclear localization (1) |
Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain. |
Senapedis et al. |
2011 |
21460183 |
Cell line |
U2OS |
EGFP-FOXO1a protein expression and DNA content |
Fluorescence |
Human Genome library |
Genome-wide |
siRNA |
Complex, sp |
Complex criteria |
|
GR00249-S |
6218 |
6218 |
RPS17 |
J-011152-09 |
-1.51417 |
Decreased vaccinia virus (VACV) infection |
|
no |
number of cells compared to control (%): 89.24 |
Vaccinia virus (VACV) infection |
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. |
Sivan et al. |
2013 |
23401514 |
Cell line |
HeLa |
Vaccinia virus VACV IHD-J/GFP protein expression and DNA content |
Fluorescence |
Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %. |
GR00249-S |
6218 |
6218 |
RPS17 |
J-011152-09 |
-1.70961 |
Decreased vaccinia virus (VACV) infection |
|
no |
number of cells compared to control (%): 89.37 |
Vaccinia virus (VACV) infection |
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. |
Sivan et al. |
2013 |
23401514 |
Cell line |
HeLa |
Vaccinia virus VACV IHD-J/GFP protein expression and DNA content |
Fluorescence |
Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %. |
GR00249-S |
6218 |
6218 |
RPS17 |
M-011152-01 |
-1.38939 |
none |
|
no |
number of cells compared to control (%): 56.20 |
Vaccinia virus (VACV) infection |
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. |
Sivan et al. |
2013 |
23401514 |
Cell line |
HeLa |
Vaccinia virus VACV IHD-J/GFP protein expression and DNA content |
Fluorescence |
Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %. |
GR00249-S |
6218 |
6218 |
RPS17 |
s12317 |
-0.42035 |
none |
|
no |
number of cells compared to control (%): 82.90 |
Vaccinia virus (VACV) infection |
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. |
Sivan et al. |
2013 |
23401514 |
Cell line |
HeLa |
Vaccinia virus VACV IHD-J/GFP protein expression and DNA content |
Fluorescence |
Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %. |
GR00249-S |
6218 |
6218 |
RPS17 |
s12318 |
-2.46836 |
Decreased viability |
|
no |
number of cells compared to control (%): 28.74 |
Vaccinia virus (VACV) infection |
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. |
Sivan et al. |
2013 |
23401514 |
Cell line |
HeLa |
Vaccinia virus VACV IHD-J/GFP protein expression and DNA content |
Fluorescence |
Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %. |
GR00249-S |
6218 |
6218 |
RPS17 |
s226971 |
-1.54677 |
Decreased vaccinia virus (VACV) infection |
|
no |
number of cells compared to control (%): 66.87 |
Vaccinia virus (VACV) infection |
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. |
Sivan et al. |
2013 |
23401514 |
Cell line |
HeLa |
Vaccinia virus VACV IHD-J/GFP protein expression and DNA content |
Fluorescence |
Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %. |
GR00249-S |
6218 |
402057 |
LOC402057 |
s196460 |
-2.46076 |
Decreased viability |
|
no |
number of cells compared to control (%): 44.58 |
Vaccinia virus (VACV) infection |
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. |
Sivan et al. |
2013 |
23401514 |
Cell line |
HeLa |
Vaccinia virus VACV IHD-J/GFP protein expression and DNA content |
Fluorescence |
Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus |
Genome-wide |
siRNA |
Z-score |
> |
Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %. |
GR00251-A-1 |
6218 |
|
RPS17 |
np |
-1 |
Decreased shRNA abundance |
|
|
|
Non-small cell lung cancer (NSCLC) cytotoxicity (1) |
Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer. |
Cron et al. |
2013 |
24040035 |
Cell line |
A549 |
shRNA abundance |
Microarray |
np |
Genome-wide |
shRNA |
Complex, sp |
Complex criteria |
All listed genes are final hits. Final hit: > |
GR00251-A-2 |
6218 |
|
RPS17 |
np |
-1 |
Decreased shRNA abundance |
|
|
|
Non-small cell lung cancer (NSCLC) cytotoxicity (2) |
Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer. |
Cron et al. |
2013 |
24040035 |
Cell line |
NCI-H460 |
shRNA abundance |
Microarray |
np |
Genome-wide |
shRNA |
Complex, sp |
Complex criteria |
All listed genes are final hits. Final hit: > |
GR00253-A |
6218 |
NM_001021 |
RPS17 |
np |
-0.486 |
none |
|
|
|
hepcidin regulation |
Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling. |
Mleczko-Sanecka et al. |
2014 |
24385536 |
Cell line |
Huh7 |
hepcidin::fluc mRNA expression |
Luminescence |
siGenome siARRAY SMARTpool |
Genome-wide |
siRNA |
Z-score |
> |
Cutoff < |
GR00255-A-1 |
6218 |
6218 |
RPS17 |
TRCN0000074883, TRCN0000074884, TRCN0000074885, TRCN0000074886, TRCN0000074887 |
-0.973227654 |
none |
|
|
|
Negative genetic interactions (1) |
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. |
Vizeacoumar et al. |
2013 |
24104479 |
Cell line |
HCT116 |
shRNA abundance |
Microarray |
np |
Genome-wide |
shRNA |
differential Gene Activity Ranking Profile (dGARP) |
< -1.0 |
HCT116 BLM-/- and HCT116 BLM+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells) |
GR00255-A-2 |
6218 |
6218 |
RPS17 |
TRCN0000074883, TRCN0000074884, TRCN0000074885, TRCN0000074886, TRCN0000074887 |
0.357374001 |
none |
|
|
|
Negative genetic interactions (2) |
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. |
Vizeacoumar et al. |
2013 |
24104479 |
Cell line |
HCT116 |
shRNA abundance |
Microarray |
np |
Genome-wide |
shRNA |
differential Gene Activity Ranking Profile (dGARP) |
< -1.0 |
HCT116 MUS81-/- and HCT116 MUS81+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells) |
GR00255-A-3 |
6218 |
6218 |
RPS17 |
TRCN0000074883, TRCN0000074884, TRCN0000074885, TRCN0000074886, TRCN0000074887 |
-0.341336116 |
none |
|
|
|
Negative genetic interactions (3) |
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. |
Vizeacoumar et al. |
2013 |
24104479 |
Cell line |
HCT116 |
shRNA abundance |
Microarray |
np |
Genome-wide |
shRNA |
differential Gene Activity Ranking Profile (dGARP) |
< -1.2 |
HCT116 PTEN-/- and HCT116 PTEN+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells) |
GR00255-A-4 |
6218 |
6218 |
RPS17 |
TRCN0000074883, TRCN0000074884, TRCN0000074885, TRCN0000074886, TRCN0000074887 |
0.936982471 |
none |
|
|
|
Negative genetic interactions (4) |
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. |
Vizeacoumar et al. |
2013 |
24104479 |
Cell line |
HCT116 |
shRNA abundance |
Microarray |
np |
Genome-wide |
shRNA |
differential Gene Activity Ranking Profile (dGARP) |
< -1.2 |
HCT116 PTTG1-/- and HCT116 PTTG1+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells) |
GR00255-A-5 |
6218 |
6218 |
RPS17 |
TRCN0000074883, TRCN0000074884, TRCN0000074885, TRCN0000074886, TRCN0000074887 |
-1.00182209 |
Negative genetic interaction between KRASG13D/+ and KRAS+/- |
|
|
|
Negative genetic interactions (5) |
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. |
Vizeacoumar et al. |
2013 |
24104479 |
Cell line |
HCT116 |
shRNA abundance |
Microarray |
np |
Genome-wide |
shRNA |
differential Gene Activity Ranking Profile (dGARP) |
< -0.8 |
HCT116 KRASG13D/- and HCT116 KRAS+/- cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells) |
GR00293-A |
6218 |
|
RPS17 |
np |
0.849 |
none |
|
|
|
Combinatorial effect with paclitaxel |
Mechanisms Promoting Escape from Mitotic Stress−Induced Tumor Cell Death |
Sinnott et al. |
2014 |
24860162 |
Cell line |
HCC366 |
Viability |
Luminescence |
Thermo-Fisher |
Genome-wide |
siRNA |
Z-score |
< -2.5 |
Final hits according to the author are indicated in the comment. |
GR00300-A |
6218 |
|
RPS17 |
TRCN0000074883, TRCN0000074885, TRCN0000074884, TRCN0000074887, TRCN0000074886 |
0 |
none |
|
|
|
Combinatorial effect with RAF inhibitor PLX4720 |
A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition. |
Whittaker et al. |
2013 |
23288408 |
Cell line |
A375 |
shRNA abundance |
Sequencing |
TRC |
Genome-wide |
shRNA |
Number of shRNAs ranked Top1000 |
> 2 |
The A375 cell line used here harbours the BRAF V600E mutation and is therefore sensitive to RAF inhibitors. |
GR00303-A |
6218 |
NM_001021 |
RPS17 |
np |
-1.18 |
none |
|
|
|
Clear cell renal cell carcinoma (ccRCC) survival regulation |
Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target |
Gerlinger et al. |
2012 |
22362593 |
Cell line |
VHL-deficient RCC4 |
Proliferation and Viability |
Fluorescence |
np |
Genome-wide |
siRNA |
Z-score |
< |
In the phenotype data duplicates were in the original document, which have been removed. |
GR00310-A-1 |
6218 |
6218 |
RPS17 |
np |
-1.33 |
none |
|
|
|
Sindbis virus (SINV) infection (1) |
Genome-Wide RNAi Screen Identifies Novel Host Proteins Required for Alphavirus Entry |
Ooi et al. |
2013 |
24367265 |
Cell line |
U2OS |
Sindbis virus (SINV) reporter |
Luminescence |
Ambion Silencer V3 |
Genome-wide |
siRNA |
Z-score |
< -3 OR > 2 |
|
|
6218 |
6218 |
RPS17 |
np |
72 |
Inconclusive |
|
|
53,9% viability |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GR00360-A-1 |
6218 |
ENSG00000184779 |
RPS17 |
249721 |
0.8002 |
Mildly decreased CFP-tsO45G cell surface transport |
|
|
|
Secretory transport (1) |
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway |
Simpson et al. |
2012 |
22660414 |
Cell line |
HeLa Kyoto |
CFP-tsO45G cell surface transport |
Fluorescence |
Ambion |
Genome-wide |
siRNA |
Deviation score |
< - 1 OR > 0.75 (mild: 0.75 - 1.0; strong: > 1.0) |
For validation screen see Secretory transport (2). |
GR00366-A-1 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.819978820112896 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (1) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
22RV1_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-1 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.782848675434888 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (1) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
22RV1_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-1 |
6218 |
|
RPS17 |
|
-0.819978820112896 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (1) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
22RV1_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-1 |
6218 |
|
RPS17 |
|
0.782848675434888 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (1) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
22RV1_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-10 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.220005371958986 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (10) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ACHN_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-10 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.33546951266813 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (10) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ACHN_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-10 |
6218 |
|
RPS17 |
|
0.220005371958986 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (10) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ACHN_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-10 |
6218 |
|
RPS17 |
|
0.33546951266813 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (10) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ACHN_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-100 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.618891659840214 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (100) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LAMA84_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-100 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.361996856406291 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (100) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LAMA84_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-100 |
6218 |
|
RPS17 |
|
-0.618891659840214 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (100) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LAMA84_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-100 |
6218 |
|
RPS17 |
|
-0.361996856406291 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (100) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LAMA84_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-101 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.272940519409724 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (101) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LK2_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-101 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.319458246381467 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (101) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LK2_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-101 |
6218 |
|
RPS17 |
|
0.272940519409724 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (101) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LK2_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-101 |
6218 |
|
RPS17 |
|
-0.319458246381467 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (101) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LK2_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-102 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.340580290998724 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (102) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN215_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-102 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.45896992480161 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (102) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN215_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-102 |
6218 |
|
RPS17 |
|
-0.340580290998724 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (102) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN215_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-102 |
6218 |
|
RPS17 |
|
-0.45896992480161 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (102) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN215_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-103 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.147247252155974 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (103) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN229_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-103 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.342544314276562 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (103) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN229_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-103 |
6218 |
|
RPS17 |
|
-0.147247252155974 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (103) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN229_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-103 |
6218 |
|
RPS17 |
|
0.342544314276562 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (103) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN229_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-104 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.138394290692698 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (104) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN235_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-104 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.215412945177609 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (104) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN235_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-104 |
6218 |
|
RPS17 |
|
0.138394290692698 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (104) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN235_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-104 |
6218 |
|
RPS17 |
|
-0.215412945177609 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (104) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN235_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-105 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.14169606775861 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (105) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN319_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-105 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-1.11030351397988 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (105) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN319_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-105 |
6218 |
|
RPS17 |
|
-1.14169606775861 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (105) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN319_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-105 |
6218 |
|
RPS17 |
|
-1.11030351397988 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (105) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN319_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-106 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.30945290278335 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (106) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN340_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-106 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.0243646765684442 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (106) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN340_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-106 |
6218 |
|
RPS17 |
|
-0.30945290278335 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (106) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN340_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-106 |
6218 |
|
RPS17 |
|
-0.0243646765684442 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (106) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN340_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-107 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.89990457952578 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (107) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN382_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-107 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.182297719845105 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (107) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN382_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-107 |
6218 |
|
RPS17 |
|
0.89990457952578 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (107) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN382_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-107 |
6218 |
|
RPS17 |
|
-0.182297719845105 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (107) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN382_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-108 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.77934496091773 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (108) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN428_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-108 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.436526058017879 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (108) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN428_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-108 |
6218 |
|
RPS17 |
|
-1.77934496091773 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (108) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN428_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-108 |
6218 |
|
RPS17 |
|
-0.436526058017879 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (108) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN428_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-109 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.00373956425353386 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (109) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN443_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-109 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.198881733552266 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (109) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN443_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-109 |
6218 |
|
RPS17 |
|
0.00373956425353386 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (109) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN443_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-109 |
6218 |
|
RPS17 |
|
0.198881733552266 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (109) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN443_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-11 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-2.87885677481134 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (11) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AGS_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-11 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.66461236592185 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (11) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AGS_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-11 |
6218 |
|
RPS17 |
|
-2.87885677481134 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (11) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AGS_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-11 |
6218 |
|
RPS17 |
|
-0.66461236592185 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (11) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AGS_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-110 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.363959216074759 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (110) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN464_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-110 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.0939295807624703 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (110) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN464_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-110 |
6218 |
|
RPS17 |
|
-0.363959216074759 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (110) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN464_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-110 |
6218 |
|
RPS17 |
|
-0.0939295807624703 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (110) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LN464_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-111 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.676419075936992 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (111) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LNZ308_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-111 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.524351020381221 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (111) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LNZ308_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-111 |
6218 |
|
RPS17 |
|
0.676419075936992 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (111) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LNZ308_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-111 |
6218 |
|
RPS17 |
|
0.524351020381221 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (111) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LNZ308_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-112 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.683355857290631 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (112) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LOVO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-112 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.287652612348297 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (112) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LOVO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-112 |
6218 |
|
RPS17 |
|
0.683355857290631 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (112) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LOVO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-112 |
6218 |
|
RPS17 |
|
-0.287652612348297 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (112) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LOVO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-113 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.336264571305462 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (113) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS411N_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-113 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.486422341668402 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (113) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS411N_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-113 |
6218 |
|
RPS17 |
|
0.336264571305462 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (113) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS411N_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-113 |
6218 |
|
RPS17 |
|
0.486422341668402 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (113) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS411N_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-114 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.41847403984914 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (114) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS513_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-114 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.0477564273287418 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (114) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS513_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-114 |
6218 |
|
RPS17 |
|
-1.41847403984914 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (114) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS513_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-114 |
6218 |
|
RPS17 |
|
0.0477564273287418 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (114) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
LS513_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-115 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.769639130557599 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (115) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MCF7_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-115 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.125682010041504 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (115) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MCF7_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-115 |
6218 |
|
RPS17 |
|
0.769639130557599 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (115) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MCF7_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-115 |
6218 |
|
RPS17 |
|
0.125682010041504 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (115) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MCF7_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-116 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-3.11911076403253 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (116) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MDAMB453_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-116 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-1.34300125321033 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (116) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MDAMB453_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-116 |
6218 |
|
RPS17 |
|
-3.11911076403253 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (116) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MDAMB453_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-116 |
6218 |
|
RPS17 |
|
-1.34300125321033 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (116) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MDAMB453_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-117 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.11905866166491 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (117) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MIAPACA2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-117 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.075925382240979 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (117) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MIAPACA2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-117 |
6218 |
|
RPS17 |
|
-1.11905866166491 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (117) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MIAPACA2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-117 |
6218 |
|
RPS17 |
|
0.075925382240979 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (117) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MIAPACA2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-118 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.130731550655857 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (118) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MKN7_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-118 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.00410716593409476 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (118) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MKN7_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-118 |
6218 |
|
RPS17 |
|
-0.130731550655857 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (118) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MKN7_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-118 |
6218 |
|
RPS17 |
|
-0.00410716593409476 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (118) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MKN7_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-119 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.59598572070541 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (119) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-119 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
2.26652431221616 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (119) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-119 |
6218 |
|
RPS17 |
|
0.59598572070541 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (119) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-119 |
6218 |
|
RPS17 |
|
2.26652431221616 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (119) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-12 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.4744807903488 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (12) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AM38_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-12 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.52574912249651 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (12) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AM38_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-12 |
6218 |
|
RPS17 |
|
1.4744807903488 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (12) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AM38_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-12 |
6218 |
|
RPS17 |
|
-0.52574912249651 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (12) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AM38_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-120 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.73303949109864 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (120) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MOLM13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-120 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.957234854059577 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (120) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MOLM13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-120 |
6218 |
|
RPS17 |
|
-1.73303949109864 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (120) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MOLM13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-120 |
6218 |
|
RPS17 |
|
0.957234854059577 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (120) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MOLM13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-121 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.109396117227823 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (121) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-121 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.390807381199577 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (121) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-121 |
6218 |
|
RPS17 |
|
-0.109396117227823 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (121) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-121 |
6218 |
|
RPS17 |
|
0.390807381199577 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (121) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-122 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.861167073376088 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (122) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-122 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-1.1060765533553 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (122) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-122 |
6218 |
|
RPS17 |
|
0.861167073376088 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (122) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-122 |
6218 |
|
RPS17 |
|
-1.1060765533553 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (122) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MONOMAC6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-123 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.29108469998986 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (123) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MV411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-123 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.434454051596685 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (123) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MV411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-123 |
6218 |
|
RPS17 |
|
-1.29108469998986 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (123) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MV411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-123 |
6218 |
|
RPS17 |
|
0.434454051596685 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (123) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
MV411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-124 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.31797049211875 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (124) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-124 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.255103786164796 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (124) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-124 |
6218 |
|
RPS17 |
|
1.31797049211875 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (124) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-124 |
6218 |
|
RPS17 |
|
0.255103786164796 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (124) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-125 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.2095592003688 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (125) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NB4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-125 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.616668344991851 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (125) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NB4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-125 |
6218 |
|
RPS17 |
|
1.2095592003688 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (125) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NB4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-125 |
6218 |
|
RPS17 |
|
0.616668344991851 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (125) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NB4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-126 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.734235913597649 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (126) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1299_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-126 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.895346672505382 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (126) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1299_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-126 |
6218 |
|
RPS17 |
|
-0.734235913597649 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (126) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1299_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-126 |
6218 |
|
RPS17 |
|
-0.895346672505382 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (126) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1299_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-127 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.0770264513125493 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (127) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1437_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-127 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.115921717882685 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (127) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1437_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-127 |
6218 |
|
RPS17 |
|
-0.0770264513125493 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (127) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1437_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-127 |
6218 |
|
RPS17 |
|
-0.115921717882685 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (127) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1437_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-128 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.203586144313496 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (128) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1650_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-128 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.809014332176336 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (128) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1650_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-128 |
6218 |
|
RPS17 |
|
-0.203586144313496 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (128) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1650_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-128 |
6218 |
|
RPS17 |
|
-0.809014332176336 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (128) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1650_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-129 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.62960252102001 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (129) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1792_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-129 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.175897665284726 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (129) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1792_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-129 |
6218 |
|
RPS17 |
|
0.62960252102001 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (129) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1792_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-129 |
6218 |
|
RPS17 |
|
-0.175897665284726 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (129) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1792_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-13 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.491773210643116 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (13) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AML193_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-13 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.681259655352364 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (13) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AML193_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-13 |
6218 |
|
RPS17 |
|
0.491773210643116 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (13) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AML193_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-13 |
6218 |
|
RPS17 |
|
-0.681259655352364 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (13) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
AML193_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-130 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.384996740503022 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (130) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH196_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-130 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.886165054373023 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (130) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH196_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-130 |
6218 |
|
RPS17 |
|
-0.384996740503022 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (130) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH196_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-130 |
6218 |
|
RPS17 |
|
-0.886165054373023 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (130) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH196_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-131 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.148169694980051 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (131) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1975_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-131 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.106011095393492 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (131) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1975_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-131 |
6218 |
|
RPS17 |
|
0.148169694980051 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (131) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1975_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-131 |
6218 |
|
RPS17 |
|
-0.106011095393492 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (131) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH1975_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-132 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.546470774156601 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (132) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2052_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-132 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.256622586573717 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (132) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2052_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-132 |
6218 |
|
RPS17 |
|
0.546470774156601 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (132) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2052_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-132 |
6218 |
|
RPS17 |
|
-0.256622586573717 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (132) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2052_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-133 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.450904792255747 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (133) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2122_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-133 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.602561608474958 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (133) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2122_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-133 |
6218 |
|
RPS17 |
|
0.450904792255747 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (133) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2122_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-133 |
6218 |
|
RPS17 |
|
0.602561608474958 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (133) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2122_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-134 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.222231343478642 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (134) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2171_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-134 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.218432337802827 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (134) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2171_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-134 |
6218 |
|
RPS17 |
|
0.222231343478642 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (134) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2171_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-134 |
6218 |
|
RPS17 |
|
0.218432337802827 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (134) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2171_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-135 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.68079677695934 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (135) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-135 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.720340017936233 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (135) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-135 |
6218 |
|
RPS17 |
|
-1.68079677695934 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (135) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-135 |
6218 |
|
RPS17 |
|
-0.720340017936233 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (135) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-136 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.53509324793466 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (136) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2452_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-136 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.691864410381642 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (136) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2452_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-136 |
6218 |
|
RPS17 |
|
1.53509324793466 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (136) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2452_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-136 |
6218 |
|
RPS17 |
|
0.691864410381642 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (136) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH2452_PLEURA |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-137 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.248095955612594 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (137) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH441_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-137 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.0893280219072163 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (137) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH441_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-137 |
6218 |
|
RPS17 |
|
0.248095955612594 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (137) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH441_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-137 |
6218 |
|
RPS17 |
|
-0.0893280219072163 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (137) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH441_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-138 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.37507608265175 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (138) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH508_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-138 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.707044694039165 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (138) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH508_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-138 |
6218 |
|
RPS17 |
|
-1.37507608265175 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (138) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH508_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-138 |
6218 |
|
RPS17 |
|
-0.707044694039165 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (138) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH508_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-139 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.156057210610737 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (139) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH660_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-139 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.66753187789886 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (139) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH660_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-139 |
6218 |
|
RPS17 |
|
-0.156057210610737 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (139) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH660_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-139 |
6218 |
|
RPS17 |
|
-0.66753187789886 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (139) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH660_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-14 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.999437588962044 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (14) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ASPC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-14 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.491972232736373 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (14) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ASPC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-14 |
6218 |
|
RPS17 |
|
-0.999437588962044 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (14) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ASPC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-14 |
6218 |
|
RPS17 |
|
0.491972232736373 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (14) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ASPC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-140 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.3972456895706 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (140) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH661_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-140 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-1.12773640981329 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (140) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH661_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-140 |
6218 |
|
RPS17 |
|
-1.3972456895706 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (140) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH661_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-140 |
6218 |
|
RPS17 |
|
-1.12773640981329 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (140) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH661_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-141 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.803929503214984 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (141) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH716_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-141 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.355053651728372 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (141) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH716_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-141 |
6218 |
|
RPS17 |
|
0.803929503214984 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (141) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH716_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-141 |
6218 |
|
RPS17 |
|
0.355053651728372 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (141) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH716_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-142 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-2.67461978562228 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (142) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH838_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-142 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.416733282153995 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (142) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH838_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-142 |
6218 |
|
RPS17 |
|
-2.67461978562228 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (142) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH838_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-142 |
6218 |
|
RPS17 |
|
0.416733282153995 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (142) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIH838_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-143 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.270535180078241 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (143) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIN87_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-143 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.123729989588211 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (143) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIN87_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-143 |
6218 |
|
RPS17 |
|
-0.270535180078241 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (143) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIN87_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-143 |
6218 |
|
RPS17 |
|
0.123729989588211 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (143) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NCIN87_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-144 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.84619808865691 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (144) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NIHOVCAR3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-144 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.114137851300061 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (144) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NIHOVCAR3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-144 |
6218 |
|
RPS17 |
|
-1.84619808865691 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (144) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NIHOVCAR3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-144 |
6218 |
|
RPS17 |
|
0.114137851300061 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (144) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NIHOVCAR3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-145 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.994440563928852 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (145) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NOMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-145 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.35682157977941 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (145) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NOMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-145 |
6218 |
|
RPS17 |
|
-0.994440563928852 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (145) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NOMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-145 |
6218 |
|
RPS17 |
|
0.35682157977941 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (145) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
NOMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-146 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.25089273024299 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (146) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OAW42_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-146 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.998074391348341 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (146) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OAW42_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-146 |
6218 |
|
RPS17 |
|
-1.25089273024299 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (146) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OAW42_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-146 |
6218 |
|
RPS17 |
|
-0.998074391348341 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (146) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OAW42_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-147 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.170451336052657 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (147) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-147 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.619418446518812 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (147) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-147 |
6218 |
|
RPS17 |
|
-0.170451336052657 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (147) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-147 |
6218 |
|
RPS17 |
|
0.619418446518812 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (147) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-148 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.695010379884231 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (148) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-148 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.449478833170913 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (148) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-148 |
6218 |
|
RPS17 |
|
-0.695010379884231 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (148) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-148 |
6218 |
|
RPS17 |
|
0.449478833170913 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (148) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-149 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.39088251742592 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (149) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-149 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.418162890340581 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (149) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-149 |
6218 |
|
RPS17 |
|
-1.39088251742592 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (149) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-149 |
6218 |
|
RPS17 |
|
0.418162890340581 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (149) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-15 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.364287114014677 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (15) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT20_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-15 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.0558369543380952 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (15) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT20_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-15 |
6218 |
|
RPS17 |
|
-0.364287114014677 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (15) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT20_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-15 |
6218 |
|
RPS17 |
|
-0.0558369543380952 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (15) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT20_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-150 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.495507258063321 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (150) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OE33_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-150 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.0133463206031494 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (150) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OE33_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-150 |
6218 |
|
RPS17 |
|
0.495507258063321 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (150) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OE33_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-150 |
6218 |
|
RPS17 |
|
0.0133463206031494 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (150) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OE33_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-151 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.885210847596909 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (151) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OELE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-151 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.208096116178555 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (151) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OELE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-151 |
6218 |
|
RPS17 |
|
-0.885210847596909 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (151) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OELE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-151 |
6218 |
|
RPS17 |
|
0.208096116178555 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (151) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OELE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-152 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.52306556107639 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (152) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OPM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-152 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
1.20502976053188 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (152) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OPM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-152 |
6218 |
|
RPS17 |
|
1.52306556107639 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (152) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OPM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-152 |
6218 |
|
RPS17 |
|
1.20502976053188 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (152) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OPM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-153 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.599502112547435 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (153) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV7_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-153 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.185118278072386 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (153) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV7_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-153 |
6218 |
|
RPS17 |
|
0.599502112547435 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (153) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV7_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-153 |
6218 |
|
RPS17 |
|
-0.185118278072386 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (153) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV7_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-154 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.032991936423342 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (154) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV90_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-154 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.553708845926406 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (154) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV90_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-154 |
6218 |
|
RPS17 |
|
-0.032991936423342 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (154) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV90_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-154 |
6218 |
|
RPS17 |
|
0.553708845926406 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (154) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OV90_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-155 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.117987382751129 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (155) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-155 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.186499759364091 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (155) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-155 |
6218 |
|
RPS17 |
|
-0.117987382751129 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (155) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-155 |
6218 |
|
RPS17 |
|
0.186499759364091 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (155) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-156 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.57313464288403 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (156) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-156 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.463521370500356 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (156) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-156 |
6218 |
|
RPS17 |
|
-1.57313464288403 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (156) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-156 |
6218 |
|
RPS17 |
|
0.463521370500356 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (156) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVCAR8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-157 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-2.43473287800337 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (157) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVISE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-157 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.460856661710621 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (157) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVISE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-157 |
6218 |
|
RPS17 |
|
-2.43473287800337 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (157) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVISE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-157 |
6218 |
|
RPS17 |
|
-0.460856661710621 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (157) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
OVISE_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-158 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.18246218949641 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (158) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0327_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-158 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.174068811631956 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (158) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0327_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-158 |
6218 |
|
RPS17 |
|
-0.18246218949641 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (158) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0327_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-158 |
6218 |
|
RPS17 |
|
-0.174068811631956 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (158) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0327_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-159 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-2.89748598930556 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (159) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0813_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-159 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.133149607372624 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (159) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0813_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-159 |
6218 |
|
RPS17 |
|
-2.89748598930556 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (159) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0813_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-159 |
6218 |
|
RPS17 |
|
0.133149607372624 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (159) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC0813_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-16 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.291986467006186 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (16) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT474_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-16 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-1.10075917653095 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (16) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT474_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-16 |
6218 |
|
RPS17 |
|
-0.291986467006186 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (16) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT474_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-16 |
6218 |
|
RPS17 |
|
-1.10075917653095 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (16) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BT474_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-160 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.0101717675434583 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (160) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC1005_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-160 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.879823808171335 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (160) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC1005_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-160 |
6218 |
|
RPS17 |
|
0.0101717675434583 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (160) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC1005_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-160 |
6218 |
|
RPS17 |
|
0.879823808171335 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (160) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PANC1005_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-161 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.499441467513287 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (161) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PLB985_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-161 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.248481793006681 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (161) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PLB985_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-161 |
6218 |
|
RPS17 |
|
-0.499441467513287 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (161) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PLB985_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-161 |
6218 |
|
RPS17 |
|
0.248481793006681 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (161) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PLB985_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-162 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.84372765593651 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (162) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PSN1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-162 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.0232622357189201 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (162) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PSN1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-162 |
6218 |
|
RPS17 |
|
-0.84372765593651 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (162) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PSN1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-162 |
6218 |
|
RPS17 |
|
0.0232622357189201 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (162) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
PSN1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-163 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.539771358093378 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (163) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
QGP1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-163 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.310886757670453 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (163) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
QGP1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-163 |
6218 |
|
RPS17 |
|
0.539771358093378 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (163) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
QGP1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-163 |
6218 |
|
RPS17 |
|
0.310886757670453 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (163) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
QGP1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-164 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.36417085919005 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (164) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-164 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.43303563647626 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (164) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-164 |
6218 |
|
RPS17 |
|
1.36417085919005 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (164) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-164 |
6218 |
|
RPS17 |
|
-0.43303563647626 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (164) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-165 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.457325254592689 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (165) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKN_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-165 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.906384751923654 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (165) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKN_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-165 |
6218 |
|
RPS17 |
|
0.457325254592689 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (165) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKN_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-165 |
6218 |
|
RPS17 |
|
-0.906384751923654 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (165) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKN_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-166 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-4.35347223247628 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (166) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-166 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.258943149851044 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (166) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-166 |
6218 |
|
RPS17 |
|
-4.35347223247628 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (166) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-166 |
6218 |
|
RPS17 |
|
-0.258943149851044 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (166) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RKO_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-167 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-2.69199031337388 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (167) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMGI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-167 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.162721863549711 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (167) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMGI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-167 |
6218 |
|
RPS17 |
|
-2.69199031337388 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (167) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMGI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-167 |
6218 |
|
RPS17 |
|
0.162721863549711 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (167) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMGI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-168 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.6022471138189 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (168) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMUGS_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-168 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.655916914416462 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (168) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMUGS_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-168 |
6218 |
|
RPS17 |
|
1.6022471138189 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (168) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMUGS_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-168 |
6218 |
|
RPS17 |
|
-0.655916914416462 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (168) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RMUGS_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-169 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.871542397923663 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (169) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RS411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-169 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.357044608228052 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (169) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RS411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-169 |
6218 |
|
RPS17 |
|
0.871542397923663 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (169) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RS411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-169 |
6218 |
|
RPS17 |
|
-0.357044608228052 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (169) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RS411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-17 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.211070789653893 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (17) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BXPC3_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-17 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.00091584357859447 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (17) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BXPC3_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-17 |
6218 |
|
RPS17 |
|
0.211070789653893 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (17) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BXPC3_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-17 |
6218 |
|
RPS17 |
|
0.00091584357859447 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (17) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
BXPC3_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-170 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.59215086140779 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (170) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RT112_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-170 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.23597055064623 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (170) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RT112_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-170 |
6218 |
|
RPS17 |
|
-0.59215086140779 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (170) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RT112_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-170 |
6218 |
|
RPS17 |
|
0.23597055064623 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (170) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
RT112_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-171 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.35930161721944 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (171) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-171 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.316591727234582 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (171) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-171 |
6218 |
|
RPS17 |
|
1.35930161721944 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (171) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-171 |
6218 |
|
RPS17 |
|
0.316591727234582 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (171) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-172 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.59718563142536 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (172) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF126_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-172 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.647409067831355 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (172) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF126_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-172 |
6218 |
|
RPS17 |
|
1.59718563142536 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (172) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF126_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-172 |
6218 |
|
RPS17 |
|
0.647409067831355 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (172) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF126_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-173 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.58993679534546 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (173) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-173 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.743154212118254 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (173) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-173 |
6218 |
|
RPS17 |
|
-1.58993679534546 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (173) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-173 |
6218 |
|
RPS17 |
|
-0.743154212118254 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (173) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-174 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.38495147417827 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (174) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF295_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-174 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.527413158344126 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (174) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF295_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-174 |
6218 |
|
RPS17 |
|
0.38495147417827 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (174) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF295_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-174 |
6218 |
|
RPS17 |
|
0.527413158344126 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (174) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF295_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-175 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.722296920444439 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (175) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF767_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-175 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.295144128494904 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (175) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF767_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-175 |
6218 |
|
RPS17 |
|
0.722296920444439 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (175) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF767_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-175 |
6218 |
|
RPS17 |
|
-0.295144128494904 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (175) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SF767_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-176 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.42846613361916 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (176) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SJSA1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-176 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.193820175959824 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (176) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SJSA1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-176 |
6218 |
|
RPS17 |
|
-0.42846613361916 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (176) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SJSA1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-176 |
6218 |
|
RPS17 |
|
-0.193820175959824 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (176) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SJSA1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-177 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.88989819857201 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (177) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKCO1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-177 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.776511404280063 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (177) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKCO1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-177 |
6218 |
|
RPS17 |
|
-1.88989819857201 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (177) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKCO1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-177 |
6218 |
|
RPS17 |
|
-0.776511404280063 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (177) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKCO1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-178 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.114888902821889 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (178) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMEL5_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-178 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.755934095953411 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (178) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMEL5_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-178 |
6218 |
|
RPS17 |
|
-0.114888902821889 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (178) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMEL5_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-178 |
6218 |
|
RPS17 |
|
0.755934095953411 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (178) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMEL5_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-179 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.862514595281034 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (179) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-179 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.942819657922242 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (179) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-179 |
6218 |
|
RPS17 |
|
0.862514595281034 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (179) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-179 |
6218 |
|
RPS17 |
|
0.942819657922242 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (179) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKMM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-18 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.692271201407705 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (18) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C2BBE1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-18 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.29868910091717 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (18) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C2BBE1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-18 |
6218 |
|
RPS17 |
|
-0.692271201407705 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (18) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C2BBE1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-18 |
6218 |
|
RPS17 |
|
-0.29868910091717 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (18) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C2BBE1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-180 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.745117796610647 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (180) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKNO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-180 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.0697351273623315 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (180) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKNO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-180 |
6218 |
|
RPS17 |
|
0.745117796610647 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (180) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKNO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-180 |
6218 |
|
RPS17 |
|
0.0697351273623315 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (180) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKNO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-181 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.605239902124219 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (181) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-181 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.89878529235535 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (181) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-181 |
6218 |
|
RPS17 |
|
-0.605239902124219 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (181) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-181 |
6218 |
|
RPS17 |
|
-0.89878529235535 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (181) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-182 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.31115041300861 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (182) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKRC20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-182 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.825388358093569 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (182) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKRC20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-182 |
6218 |
|
RPS17 |
|
1.31115041300861 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (182) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKRC20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-182 |
6218 |
|
RPS17 |
|
0.825388358093569 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (182) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SKRC20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-183 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.2342509903199 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (183) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-183 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.991294392844652 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (183) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-183 |
6218 |
|
RPS17 |
|
1.2342509903199 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (183) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-183 |
6218 |
|
RPS17 |
|
0.991294392844652 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (183) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR20_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-184 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.467441146516532 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (184) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR21_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-184 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.0864810369721578 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (184) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR21_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-184 |
6218 |
|
RPS17 |
|
0.467441146516532 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (184) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR21_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-184 |
6218 |
|
RPS17 |
|
-0.0864810369721578 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (184) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR21_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-185 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.169667945719926 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (185) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR23_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-185 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.0268484508780551 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (185) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR23_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-185 |
6218 |
|
RPS17 |
|
0.169667945719926 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (185) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR23_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-185 |
6218 |
|
RPS17 |
|
0.0268484508780551 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (185) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR23_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-186 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.2290356024222 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (186) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR24_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-186 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.454342669764752 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (186) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR24_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-186 |
6218 |
|
RPS17 |
|
-1.2290356024222 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (186) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR24_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-186 |
6218 |
|
RPS17 |
|
0.454342669764752 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (186) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR24_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-187 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.653764553514246 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (187) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR25_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-187 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.0682145484696197 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (187) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR25_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-187 |
6218 |
|
RPS17 |
|
-0.653764553514246 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (187) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR25_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-187 |
6218 |
|
RPS17 |
|
0.0682145484696197 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (187) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR25_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-188 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.349138455522056 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (188) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR26_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-188 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.728363540986691 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (188) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR26_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-188 |
6218 |
|
RPS17 |
|
0.349138455522056 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (188) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR26_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-188 |
6218 |
|
RPS17 |
|
0.728363540986691 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (188) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SLR26_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-189 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.53249156591956 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (189) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU1105_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-189 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.134728982768316 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (189) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU1105_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-189 |
6218 |
|
RPS17 |
|
1.53249156591956 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (189) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU1105_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-189 |
6218 |
|
RPS17 |
|
0.134728982768316 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (189) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU1105_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-19 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.458663440318155 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (19) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C32_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-19 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.221734965073694 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (19) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C32_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-19 |
6218 |
|
RPS17 |
|
-0.458663440318155 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (19) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C32_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-19 |
6218 |
|
RPS17 |
|
0.221734965073694 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (19) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
C32_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-190 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.03522868174221 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (190) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU840_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-190 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.763741792550269 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (190) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU840_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-190 |
6218 |
|
RPS17 |
|
-1.03522868174221 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (190) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU840_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-190 |
6218 |
|
RPS17 |
|
-0.763741792550269 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (190) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNU840_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-191 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.97519353430128 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (191) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-191 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.418019212671336 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (191) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-191 |
6218 |
|
RPS17 |
|
-1.97519353430128 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (191) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-191 |
6218 |
|
RPS17 |
|
0.418019212671336 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (191) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-192 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.67860305769607 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (192) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC2A_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-192 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.341593319378196 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (192) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC2A_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-192 |
6218 |
|
RPS17 |
|
1.67860305769607 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (192) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC2A_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-192 |
6218 |
|
RPS17 |
|
-0.341593319378196 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (192) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SNUC2A_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-193 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.635710787173431 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (193) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SU8686_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-193 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.66872032860504 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (193) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SU8686_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-193 |
6218 |
|
RPS17 |
|
-0.635710787173431 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (193) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SU8686_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-193 |
6218 |
|
RPS17 |
|
-0.66872032860504 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (193) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SU8686_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-194 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.856434337666053 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (194) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1417_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-194 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.160157299705073 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (194) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1417_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-194 |
6218 |
|
RPS17 |
|
0.856434337666053 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (194) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1417_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-194 |
6218 |
|
RPS17 |
|
-0.160157299705073 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (194) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1417_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-195 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.199868081564219 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (195) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1783_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-195 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.353952441922341 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (195) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1783_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-195 |
6218 |
|
RPS17 |
|
0.199868081564219 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (195) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1783_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-195 |
6218 |
|
RPS17 |
|
-0.353952441922341 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (195) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW1783_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-196 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.17093342241126 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (196) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW480_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-196 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.353023316590689 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (196) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW480_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-196 |
6218 |
|
RPS17 |
|
0.17093342241126 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (196) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW480_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-196 |
6218 |
|
RPS17 |
|
-0.353023316590689 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (196) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW480_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-197 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.711687625580805 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (197) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW48_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-197 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.19040296319559 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (197) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW48_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-197 |
6218 |
|
RPS17 |
|
0.711687625580805 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (197) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW48_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-197 |
6218 |
|
RPS17 |
|
-0.19040296319559 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (197) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
SW48_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-198 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.831856279355898 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (198) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
T98G_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-198 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.532475307579369 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (198) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
T98G_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-198 |
6218 |
|
RPS17 |
|
0.831856279355898 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (198) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
T98G_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-198 |
6218 |
|
RPS17 |
|
-0.532475307579369 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (198) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
T98G_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-199 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.12947599902014 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (199) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TC71_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-199 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
1.18548209837101 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (199) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TC71_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-199 |
6218 |
|
RPS17 |
|
1.12947599902014 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (199) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TC71_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-199 |
6218 |
|
RPS17 |
|
1.18548209837101 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (199) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TC71_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-2 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.24163109874157 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (2) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
697_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-2 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.728857700776356 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (2) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
697_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-2 |
6218 |
|
RPS17 |
|
1.24163109874157 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (2) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
697_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-2 |
6218 |
|
RPS17 |
|
0.728857700776356 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (2) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
697_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-20 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.714061702856757 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (20) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CADOES1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-20 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.997523235431415 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (20) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CADOES1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-20 |
6218 |
|
RPS17 |
|
-0.714061702856757 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (20) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CADOES1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-20 |
6218 |
|
RPS17 |
|
0.997523235431415 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (20) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CADOES1_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-200 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.272367334572558 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (200) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TCCSUP_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-200 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.0320143227818371 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (200) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TCCSUP_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-200 |
6218 |
|
RPS17 |
|
0.272367334572558 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (200) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TCCSUP_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-200 |
6218 |
|
RPS17 |
|
0.0320143227818371 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (200) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TCCSUP_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-201 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.680456690647561 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (201) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE10_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-201 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.398339247813751 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (201) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE10_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-201 |
6218 |
|
RPS17 |
|
-0.680456690647561 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (201) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE10_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-201 |
6218 |
|
RPS17 |
|
-0.398339247813751 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (201) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE10_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-202 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.00292802392509832 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (202) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE15_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-202 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.486140816471317 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (202) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE15_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-202 |
6218 |
|
RPS17 |
|
0.00292802392509832 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (202) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE15_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-202 |
6218 |
|
RPS17 |
|
0.486140816471317 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (202) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE15_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-203 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.69769073518566 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (203) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE9_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-203 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.0465635996599676 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (203) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE9_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-203 |
6218 |
|
RPS17 |
|
1.69769073518566 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (203) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE9_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-203 |
6218 |
|
RPS17 |
|
-0.0465635996599676 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (203) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TE9_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-204 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.814772768394678 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (204) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-204 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.659833057179382 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (204) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-204 |
6218 |
|
RPS17 |
|
-0.814772768394678 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (204) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-204 |
6218 |
|
RPS17 |
|
-0.659833057179382 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (204) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-205 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.0176961623752777 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (205) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV112D_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-205 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.385938454865581 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (205) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV112D_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-205 |
6218 |
|
RPS17 |
|
0.0176961623752777 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (205) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV112D_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-205 |
6218 |
|
RPS17 |
|
-0.385938454865581 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (205) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV112D_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-206 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-2.81158846999984 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (206) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV21G_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-206 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.462282255688571 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (206) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV21G_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-206 |
6218 |
|
RPS17 |
|
-2.81158846999984 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (206) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV21G_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-206 |
6218 |
|
RPS17 |
|
-0.462282255688571 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (206) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TOV21G_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-207 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.494825009674957 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (207) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TT_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-207 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
1.85357882461986 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (207) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TT_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-207 |
6218 |
|
RPS17 |
|
0.494825009674957 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (207) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TT_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-207 |
6218 |
|
RPS17 |
|
1.85357882461986 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (207) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TT_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-208 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.1693187107801 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (208) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TYKNU_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-208 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.537057130921739 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (208) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TYKNU_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-208 |
6218 |
|
RPS17 |
|
1.1693187107801 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (208) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TYKNU_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-208 |
6218 |
|
RPS17 |
|
-0.537057130921739 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (208) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
TYKNU_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-209 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.418686627071126 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (209) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U178_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-209 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
1.32870313580008 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (209) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U178_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-209 |
6218 |
|
RPS17 |
|
-0.418686627071126 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (209) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U178_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-209 |
6218 |
|
RPS17 |
|
1.32870313580008 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (209) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U178_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-21 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.246494517917244 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (21) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL120_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-21 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.401223607656259 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (21) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL120_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-21 |
6218 |
|
RPS17 |
|
0.246494517917244 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (21) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL120_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-21 |
6218 |
|
RPS17 |
|
-0.401223607656259 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (21) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL120_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-210 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.09574367527258 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (210) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U251MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-210 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.423146425354104 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (210) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U251MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-210 |
6218 |
|
RPS17 |
|
-1.09574367527258 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (210) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U251MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-210 |
6218 |
|
RPS17 |
|
-0.423146425354104 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (210) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U251MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-211 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.15265193292112 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (211) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U343_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-211 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
1.59107314201459 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (211) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U343_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-211 |
6218 |
|
RPS17 |
|
1.15265193292112 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (211) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U343_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-211 |
6218 |
|
RPS17 |
|
1.59107314201459 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (211) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U343_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-212 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.55657537254634 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (212) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U87MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-212 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.126760667998364 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (212) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U87MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-212 |
6218 |
|
RPS17 |
|
1.55657537254634 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (212) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U87MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-212 |
6218 |
|
RPS17 |
|
0.126760667998364 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (212) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
U87MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-213 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.412462224503264 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (213) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
UOK101_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-213 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
2.32282720961929 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (213) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
UOK101_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-213 |
6218 |
|
RPS17 |
|
0.412462224503264 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (213) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
UOK101_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-213 |
6218 |
|
RPS17 |
|
2.32282720961929 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (213) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
UOK101_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-214 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.169759751484812 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (214) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
VCAP_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-214 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.290450902278801 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (214) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
VCAP_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-214 |
6218 |
|
RPS17 |
|
0.169759751484812 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (214) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
VCAP_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-214 |
6218 |
|
RPS17 |
|
-0.290450902278801 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (214) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
VCAP_PROSTATE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-215 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.12447265556245 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (215) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
YKG1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-215 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.577752067704657 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (215) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
YKG1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-215 |
6218 |
|
RPS17 |
|
-1.12447265556245 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (215) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
YKG1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-215 |
6218 |
|
RPS17 |
|
-0.577752067704657 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (215) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
YKG1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-216 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.223747906815082 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (216) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ZR7530_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-216 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-1.20255415064504 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (216) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ZR7530_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-216 |
6218 |
|
RPS17 |
|
0.223747906815082 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (216) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ZR7530_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-216 |
6218 |
|
RPS17 |
|
-1.20255415064504 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (216) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
ZR7530_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-22 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.75762683843585 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (22) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL51_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-22 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.738288423289662 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (22) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL51_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-22 |
6218 |
|
RPS17 |
|
-1.75762683843585 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (22) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL51_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-22 |
6218 |
|
RPS17 |
|
0.738288423289662 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (22) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAL51_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-23 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.00731166615257 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (23) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CALU1_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-23 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.282990052073939 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (23) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CALU1_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-23 |
6218 |
|
RPS17 |
|
1.00731166615257 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (23) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CALU1_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-23 |
6218 |
|
RPS17 |
|
0.282990052073939 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (23) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CALU1_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-24 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.168602489601087 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (24) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-24 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.0136830418066713 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (24) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-24 |
6218 |
|
RPS17 |
|
0.168602489601087 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (24) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-24 |
6218 |
|
RPS17 |
|
-0.0136830418066713 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (24) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV3_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-25 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.277433626513105 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (25) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-25 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.655904406942447 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (25) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-25 |
6218 |
|
RPS17 |
|
-0.277433626513105 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (25) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-25 |
6218 |
|
RPS17 |
|
-0.655904406942447 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (25) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAOV4_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-26 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.737387298543944 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (26) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-26 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.878576041436013 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (26) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-26 |
6218 |
|
RPS17 |
|
0.737387298543944 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (26) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-26 |
6218 |
|
RPS17 |
|
0.878576041436013 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (26) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CAS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-27 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.677272063244028 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (27) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CFPAC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-27 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.870191084350182 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (27) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CFPAC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-27 |
6218 |
|
RPS17 |
|
0.677272063244028 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (27) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CFPAC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-27 |
6218 |
|
RPS17 |
|
-0.870191084350182 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (27) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CFPAC1_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-28 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.4969471746093 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (28) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CH157MN_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-28 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.152906979645681 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (28) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CH157MN_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-28 |
6218 |
|
RPS17 |
|
-1.4969471746093 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (28) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CH157MN_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-28 |
6218 |
|
RPS17 |
|
-0.152906979645681 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (28) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CH157MN_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-29 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.136163085254243 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (29) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO205_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-29 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.58130142522152 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (29) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO205_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-29 |
6218 |
|
RPS17 |
|
0.136163085254243 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (29) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO205_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-29 |
6218 |
|
RPS17 |
|
-0.58130142522152 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (29) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO205_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-3 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.0366962778179287 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (3) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
786O_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-3 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.114614131065788 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (3) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
786O_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-3 |
6218 |
|
RPS17 |
|
-0.0366962778179287 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (3) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
786O_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-3 |
6218 |
|
RPS17 |
|
0.114614131065788 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (3) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
786O_KIDNEY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-30 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.68124265025814 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (30) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO704_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-30 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.0802543162667894 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (30) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO704_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-30 |
6218 |
|
RPS17 |
|
-1.68124265025814 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (30) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO704_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-30 |
6218 |
|
RPS17 |
|
-0.0802543162667894 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (30) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO704_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-31 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.298345678347448 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (31) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO741_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-31 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.0884990476879782 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (31) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO741_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-31 |
6218 |
|
RPS17 |
|
0.298345678347448 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (31) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO741_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-31 |
6218 |
|
RPS17 |
|
0.0884990476879782 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (31) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO741_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-32 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.129699336994258 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (32) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO783_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-32 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
1.02748022949851 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (32) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO783_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-32 |
6218 |
|
RPS17 |
|
-0.129699336994258 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (32) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO783_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-32 |
6218 |
|
RPS17 |
|
1.02748022949851 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (32) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COLO783_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-33 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.351185766516207 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (33) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CORL23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-33 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.539525353150101 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (33) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CORL23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-33 |
6218 |
|
RPS17 |
|
0.351185766516207 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (33) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CORL23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-33 |
6218 |
|
RPS17 |
|
-0.539525353150101 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (33) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
CORL23_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-34 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.0645248826170368 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (34) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV362_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-34 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.385697645781247 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (34) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV362_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-34 |
6218 |
|
RPS17 |
|
0.0645248826170368 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (34) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV362_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-34 |
6218 |
|
RPS17 |
|
-0.385697645781247 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (34) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV362_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-35 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.68243270718023 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (35) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV434_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-35 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.0602954973787322 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (35) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV434_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-35 |
6218 |
|
RPS17 |
|
-0.68243270718023 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (35) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV434_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-35 |
6218 |
|
RPS17 |
|
0.0602954973787322 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (35) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV434_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-36 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.4354322196737 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (36) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV504_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-36 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.319801690150603 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (36) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV504_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-36 |
6218 |
|
RPS17 |
|
1.4354322196737 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (36) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV504_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-36 |
6218 |
|
RPS17 |
|
0.319801690150603 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (36) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV504_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-37 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-3.02123789705653 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (37) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV644_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-37 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.784969452035038 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (37) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV644_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-37 |
6218 |
|
RPS17 |
|
-3.02123789705653 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (37) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV644_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-37 |
6218 |
|
RPS17 |
|
0.784969452035038 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (37) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
COV644_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-38 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.07224493589322 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (38) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DBTRG05MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-38 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.207067378415261 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (38) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DBTRG05MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-38 |
6218 |
|
RPS17 |
|
1.07224493589322 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (38) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DBTRG05MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-38 |
6218 |
|
RPS17 |
|
0.207067378415261 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (38) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DBTRG05MG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-39 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.22549803914287 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (39) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DKMG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-39 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.0916799080343648 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (39) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DKMG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-39 |
6218 |
|
RPS17 |
|
1.22549803914287 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (39) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DKMG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-39 |
6218 |
|
RPS17 |
|
-0.0916799080343648 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (39) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DKMG_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-4 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.520954712723233 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (4) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A1207_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-4 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
1.02490747839719 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (4) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A1207_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-4 |
6218 |
|
RPS17 |
|
0.520954712723233 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (4) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A1207_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-4 |
6218 |
|
RPS17 |
|
1.02490747839719 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (4) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A1207_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-40 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-1.07362182038741 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (40) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DLD1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-40 |
6218 |
|
RPS17 |
|
0.419904574121471 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (40) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DLD1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-40 |
6218 |
|
RPS17 |
|
-1.07362182038741 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (40) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DLD1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-40 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.419904574121471 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (40) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
DLD1_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-41 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-2.52949566555442 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (41) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFE184_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-41 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.193977286032183 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (41) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFE184_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-41 |
6218 |
|
RPS17 |
|
-2.52949566555442 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (41) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFE184_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-41 |
6218 |
|
RPS17 |
|
-0.193977286032183 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (41) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFE184_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-42 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.37235048407265 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (42) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFM19_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-42 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.248847122621018 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (42) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFM19_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-42 |
6218 |
|
RPS17 |
|
-1.37235048407265 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (42) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFM19_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-42 |
6218 |
|
RPS17 |
|
0.248847122621018 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (42) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFM19_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-43 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.68252550314597 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (43) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO21_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-43 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-1.11999299603527 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (43) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO21_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-43 |
6218 |
|
RPS17 |
|
-0.68252550314597 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (43) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO21_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-43 |
6218 |
|
RPS17 |
|
-1.11999299603527 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (43) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO21_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-44 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.592035432279674 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (44) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO27_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-44 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.373644501702433 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (44) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO27_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-44 |
6218 |
|
RPS17 |
|
0.592035432279674 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (44) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO27_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-44 |
6218 |
|
RPS17 |
|
-0.373644501702433 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (44) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EFO27_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-45 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.347291872386724 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (45) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EW8_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-45 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.342945055950252 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (45) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EW8_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-45 |
6218 |
|
RPS17 |
|
0.347291872386724 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (45) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EW8_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-45 |
6218 |
|
RPS17 |
|
0.342945055950252 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (45) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EW8_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-46 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.147572038036066 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (46) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EWS502_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-46 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.349928697887414 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (46) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EWS502_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-46 |
6218 |
|
RPS17 |
|
-0.147572038036066 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (46) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EWS502_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-46 |
6218 |
|
RPS17 |
|
-0.349928697887414 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (46) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
EWS502_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-47 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.12114515632142 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (47) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-47 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.468435142738548 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (47) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-47 |
6218 |
|
RPS17 |
|
-1.12114515632142 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (47) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-47 |
6218 |
|
RPS17 |
|
0.468435142738548 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (47) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-48 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.0994457303038525 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (48) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GB1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-48 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.443673154187287 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (48) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GB1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-48 |
6218 |
|
RPS17 |
|
-0.0994457303038525 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (48) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GB1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-48 |
6218 |
|
RPS17 |
|
-0.443673154187287 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (48) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GB1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-49 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-2.11371414633148 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (49) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GP2D_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-49 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.758019128629269 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (49) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GP2D_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-49 |
6218 |
|
RPS17 |
|
-2.11371414633148 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (49) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GP2D_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-49 |
6218 |
|
RPS17 |
|
-0.758019128629269 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (49) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
GP2D_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-5 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.638012013957986 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (5) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-5 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.279206821667402 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (5) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-5 |
6218 |
|
RPS17 |
|
0.638012013957986 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (5) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-5 |
6218 |
|
RPS17 |
|
0.279206821667402 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (5) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A172_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-50 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.828763457717251 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (50) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1187_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-50 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.298503353148876 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (50) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1187_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-50 |
6218 |
|
RPS17 |
|
0.828763457717251 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (50) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1187_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-50 |
6218 |
|
RPS17 |
|
-0.298503353148876 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (50) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1187_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-51 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.0929515687319243 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (51) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1395_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-51 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.297263806872655 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (51) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1395_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-51 |
6218 |
|
RPS17 |
|
0.0929515687319243 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (51) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1395_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-51 |
6218 |
|
RPS17 |
|
-0.297263806872655 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (51) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1395_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-52 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.0941609099362 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (52) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1954_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-52 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.996105111298163 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (52) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1954_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-52 |
6218 |
|
RPS17 |
|
-1.0941609099362 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (52) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1954_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-52 |
6218 |
|
RPS17 |
|
-0.996105111298163 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (52) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC1954_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-53 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-2.20786923347274 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (53) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2218_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-53 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.493226682860232 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (53) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2218_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-53 |
6218 |
|
RPS17 |
|
-2.20786923347274 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (53) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2218_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-53 |
6218 |
|
RPS17 |
|
-0.493226682860232 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (53) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2218_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-54 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.1902284992982 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (54) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2814_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-54 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.211574092440488 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (54) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2814_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-54 |
6218 |
|
RPS17 |
|
-1.1902284992982 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (54) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2814_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-54 |
6218 |
|
RPS17 |
|
-0.211574092440488 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (54) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC2814_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-55 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.984930014793715 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (55) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC364_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-55 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.958015765521277 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (55) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC364_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-55 |
6218 |
|
RPS17 |
|
0.984930014793715 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (55) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC364_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-55 |
6218 |
|
RPS17 |
|
-0.958015765521277 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (55) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC364_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-56 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.476459188607887 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (56) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC44_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-56 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.0632769372050977 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (56) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC44_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-56 |
6218 |
|
RPS17 |
|
-0.476459188607887 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (56) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC44_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-56 |
6218 |
|
RPS17 |
|
-0.0632769372050977 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (56) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC44_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-57 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-2.43170611690741 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (57) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC70_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-57 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.526292547554741 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (57) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC70_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-57 |
6218 |
|
RPS17 |
|
-2.43170611690741 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (57) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC70_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-57 |
6218 |
|
RPS17 |
|
-0.526292547554741 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (57) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC70_BREAST |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-58 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.665682610992258 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (58) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827GR5_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-58 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.374854230368346 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (58) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827GR5_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-58 |
6218 |
|
RPS17 |
|
0.665682610992258 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (58) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827GR5_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-58 |
6218 |
|
RPS17 |
|
-0.374854230368346 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (58) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827GR5_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-59 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.212870408977295 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (59) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-59 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.237408356592689 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (59) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-59 |
6218 |
|
RPS17 |
|
-0.212870408977295 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (59) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-59 |
6218 |
|
RPS17 |
|
0.237408356592689 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (59) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCC827_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-6 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.09754654811308 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (6) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A204_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-6 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.171260218088601 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (6) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A204_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-6 |
6218 |
|
RPS17 |
|
1.09754654811308 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (6) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A204_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-6 |
6218 |
|
RPS17 |
|
0.171260218088601 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (6) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A204_SOFT_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-60 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.326510385607836 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (60) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCT116_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-60 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.224841924407965 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (60) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCT116_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-60 |
6218 |
|
RPS17 |
|
0.326510385607836 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (60) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCT116_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-60 |
6218 |
|
RPS17 |
|
-0.224841924407965 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (60) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HCT116_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-61 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.306300244721672 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (61) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEC1A_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-61 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.910935654888166 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (61) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEC1A_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-61 |
6218 |
|
RPS17 |
|
-0.306300244721672 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (61) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEC1A_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-61 |
6218 |
|
RPS17 |
|
0.910935654888166 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (61) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEC1A_ENDOMETRIUM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-62 |
6218 |
|
RPS17 |
|
-0.218839238001238 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (62) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEYA8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-62 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.757861964515375 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (62) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEYA8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-62 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.218839238001238 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (62) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEYA8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-62 |
6218 |
|
RPS17 |
|
-0.757861964515375 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (62) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HEYA8_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-63 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.959462756116722 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (63) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-63 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.224407887187223 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (63) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-63 |
6218 |
|
RPS17 |
|
-0.959462756116722 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (63) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-63 |
6218 |
|
RPS17 |
|
0.224407887187223 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (63) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-64 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.39312122009941 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (64) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HLF_LIVER |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-64 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.697285402080956 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (64) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HLF_LIVER |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-64 |
6218 |
|
RPS17 |
|
-1.39312122009941 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (64) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HLF_LIVER |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-64 |
6218 |
|
RPS17 |
|
0.697285402080956 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (64) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HLF_LIVER |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-65 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.640890244925858 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (65) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HNT34_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-65 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
1.20695867255144 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (65) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HNT34_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-65 |
6218 |
|
RPS17 |
|
0.640890244925858 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (65) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HNT34_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-65 |
6218 |
|
RPS17 |
|
1.20695867255144 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (65) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HNT34_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-66 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.499392240385119 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (66) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAC_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-66 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.672642742588141 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (66) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAC_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-66 |
6218 |
|
RPS17 |
|
0.499392240385119 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (66) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAC_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-66 |
6218 |
|
RPS17 |
|
-0.672642742588141 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (66) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAC_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-67 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.294305941777906 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (67) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAFII_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-67 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.0339910326158484 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (67) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAFII_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-67 |
6218 |
|
RPS17 |
|
-0.294305941777906 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (67) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAFII_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-67 |
6218 |
|
RPS17 |
|
-0.0339910326158484 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (67) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HPAFII_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-68 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.233425281217895 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (68) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS683_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-68 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
1.41236315364157 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (68) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS683_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-68 |
6218 |
|
RPS17 |
|
0.233425281217895 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (68) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS683_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-68 |
6218 |
|
RPS17 |
|
1.41236315364157 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (68) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS683_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-69 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.876864303141792 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (69) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS766T_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-69 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.8682767498497 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (69) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS766T_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-69 |
6218 |
|
RPS17 |
|
-0.876864303141792 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (69) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS766T_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-69 |
6218 |
|
RPS17 |
|
0.8682767498497 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (69) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS766T_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-7 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-2.85750309339615 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (7) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A2058_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-7 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.437916690285171 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (7) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A2058_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-7 |
6218 |
|
RPS17 |
|
-2.85750309339615 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (7) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A2058_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-7 |
6218 |
|
RPS17 |
|
-0.437916690285171 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (7) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A2058_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-70 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.43832487928259 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (70) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS944T_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-70 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.203118272099507 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (70) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS944T_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-70 |
6218 |
|
RPS17 |
|
-1.43832487928259 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (70) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS944T_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-70 |
6218 |
|
RPS17 |
|
0.203118272099507 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (70) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HS944T_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-71 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.507133347746687 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (71) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT1197_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-71 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.283348660327533 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (71) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT1197_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-71 |
6218 |
|
RPS17 |
|
-0.507133347746687 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (71) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT1197_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-71 |
6218 |
|
RPS17 |
|
0.283348660327533 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (71) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT1197_URINARY_TRACT |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-72 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.06429786675404 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (72) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT29_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-72 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.727095736208805 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (72) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT29_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-72 |
6218 |
|
RPS17 |
|
-1.06429786675404 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (72) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT29_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-72 |
6218 |
|
RPS17 |
|
-0.727095736208805 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (72) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT29_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-73 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.298613739864336 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (73) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT55_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-73 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-1.03033577376325 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (73) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT55_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-73 |
6218 |
|
RPS17 |
|
-0.298613739864336 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (73) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT55_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-73 |
6218 |
|
RPS17 |
|
-1.03033577376325 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (73) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HT55_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-74 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.65672089193939 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (74) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUG1N_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-74 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.100658483011126 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (74) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUG1N_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-74 |
6218 |
|
RPS17 |
|
-1.65672089193939 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (74) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUG1N_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-74 |
6218 |
|
RPS17 |
|
0.100658483011126 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (74) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUG1N_STOMACH |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-75 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.240048404662943 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (75) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUTU80_SMALL_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-75 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.111361647997571 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (75) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUTU80_SMALL_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-75 |
6218 |
|
RPS17 |
|
-0.240048404662943 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (75) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUTU80_SMALL_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-75 |
6218 |
|
RPS17 |
|
0.111361647997571 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (75) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
HUTU80_SMALL_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-76 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.49070028033632 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (76) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGR39_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-76 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.015496916626371 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (76) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGR39_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-76 |
6218 |
|
RPS17 |
|
1.49070028033632 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (76) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGR39_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-76 |
6218 |
|
RPS17 |
|
0.015496916626371 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (76) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGR39_SKIN |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-77 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.461017855034293 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (77) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGROV1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-77 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.938272865091485 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (77) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGROV1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-77 |
6218 |
|
RPS17 |
|
-0.461017855034293 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (77) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGROV1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-77 |
6218 |
|
RPS17 |
|
-0.938272865091485 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (77) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IGROV1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-78 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.213997257549078 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (78) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IOMMLEE_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-78 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.740016382687818 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (78) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IOMMLEE_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-78 |
6218 |
|
RPS17 |
|
0.213997257549078 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (78) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IOMMLEE_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-78 |
6218 |
|
RPS17 |
|
0.740016382687818 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (78) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
IOMMLEE_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-79 |
6218 |
|
RPS17 |
|
-0.358058349709057 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (79) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHESOAD1_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-79 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.0331908483848 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (79) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHESOAD1_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-79 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.358058349709057 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (79) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHESOAD1_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-79 |
6218 |
|
RPS17 |
|
-1.0331908483848 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (79) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHESOAD1_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-8 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.354005009804637 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (8) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A549_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-8 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.198656225581976 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (8) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A549_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-8 |
6218 |
|
RPS17 |
|
0.354005009804637 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (8) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A549_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-8 |
6218 |
|
RPS17 |
|
-0.198656225581976 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (8) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A549_LUNG |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-80 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-2.30131760011881 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (80) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOC5_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-80 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.36106667989047 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (80) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOC5_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-80 |
6218 |
|
RPS17 |
|
-2.30131760011881 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (80) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOC5_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-80 |
6218 |
|
RPS17 |
|
-0.36106667989047 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (80) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOC5_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-81 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.105413670850544 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (81) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOM1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-81 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.660507868938524 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (81) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOM1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-81 |
6218 |
|
RPS17 |
|
0.105413670850544 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (81) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOM1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-81 |
6218 |
|
RPS17 |
|
0.660507868938524 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (81) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JHOM1_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-82 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.997830917347895 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (82) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JJN3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-82 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.88591904940563 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (82) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JJN3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-82 |
6218 |
|
RPS17 |
|
-0.997830917347895 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (82) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JJN3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-82 |
6218 |
|
RPS17 |
|
0.88591904940563 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (82) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
JJN3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-83 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.407223213242336 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (83) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-83 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.512511329335885 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (83) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-83 |
6218 |
|
RPS17 |
|
0.407223213242336 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (83) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-83 |
6218 |
|
RPS17 |
|
-0.512511329335885 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (83) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-84 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.188845024200902 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (84) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KALS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-84 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.8996178072448 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (84) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KALS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-84 |
6218 |
|
RPS17 |
|
0.188845024200902 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (84) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KALS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-84 |
6218 |
|
RPS17 |
|
0.8996178072448 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (84) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KALS1_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-85 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.175105987352495 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (85) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-85 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.322725006618115 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (85) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-85 |
6218 |
|
RPS17 |
|
0.175105987352495 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (85) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-85 |
6218 |
|
RPS17 |
|
-0.322725006618115 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (85) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-86 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.423762538105684 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (86) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KM12_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-86 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.344065532017322 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (86) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KM12_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-86 |
6218 |
|
RPS17 |
|
0.423762538105684 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (86) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KM12_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-86 |
6218 |
|
RPS17 |
|
-0.344065532017322 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (86) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KM12_LARGE_INTESTINE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-87 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
1.57727240933811 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (87) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KMS12BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-87 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.144916281412784 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (87) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KMS12BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-87 |
6218 |
|
RPS17 |
|
1.57727240933811 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (87) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KMS12BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-87 |
6218 |
|
RPS17 |
|
0.144916281412784 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (87) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KMS12BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-88 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.413127215105317 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (88) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS60_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-88 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.168855621045119 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (88) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS60_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-88 |
6218 |
|
RPS17 |
|
0.413127215105317 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (88) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS60_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-88 |
6218 |
|
RPS17 |
|
0.168855621045119 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (88) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS60_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-89 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.56246947240078 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (89) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS81_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-89 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.375785483501246 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (89) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS81_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-89 |
6218 |
|
RPS17 |
|
-1.56246947240078 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (89) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS81_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-89 |
6218 |
|
RPS17 |
|
-0.375785483501246 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (89) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KNS81_CENTRAL_NERVOUS_SYSTEM |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-9 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.20138509231953 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (9) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A673_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-9 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.824297576701813 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (9) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A673_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-9 |
6218 |
|
RPS17 |
|
-1.20138509231953 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (9) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A673_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-9 |
6218 |
|
RPS17 |
|
0.824297576701813 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (9) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
A673_BONE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-90 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.284106872982332 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (90) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP1NL_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-90 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.353385828122299 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (90) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP1NL_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-90 |
6218 |
|
RPS17 |
|
0.284106872982332 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (90) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP1NL_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-90 |
6218 |
|
RPS17 |
|
-0.353385828122299 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (90) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP1NL_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-91 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.027311719953352 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (91) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-91 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
1.33439251095338 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (91) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-91 |
6218 |
|
RPS17 |
|
0.027311719953352 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (91) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-91 |
6218 |
|
RPS17 |
|
1.33439251095338 |
Increased shRNA abundance (Z-score > 2) |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (91) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP2_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-92 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.555241407491735 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (92) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP4_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-92 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.598107743331347 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (92) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP4_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-92 |
6218 |
|
RPS17 |
|
0.555241407491735 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (92) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP4_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-92 |
6218 |
|
RPS17 |
|
-0.598107743331347 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (92) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KP4_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-93 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-3.30029842357266 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (93) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KURAMOCHI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-93 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.435206771341141 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (93) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KURAMOCHI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-93 |
6218 |
|
RPS17 |
|
-3.30029842357266 |
Decreased shRNA abundance (Z-score < -2) |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (93) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KURAMOCHI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-93 |
6218 |
|
RPS17 |
|
-0.435206771341141 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (93) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KURAMOCHI_OVARY |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-94 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.713128650737816 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (94) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE150_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-94 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.202686760378336 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (94) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE150_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-94 |
6218 |
|
RPS17 |
|
0.713128650737816 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (94) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE150_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-94 |
6218 |
|
RPS17 |
|
0.202686760378336 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (94) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE150_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-95 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.49341899466187 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (95) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE30_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-95 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.0592043399961363 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (95) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE30_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-95 |
6218 |
|
RPS17 |
|
-1.49341899466187 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (95) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE30_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-95 |
6218 |
|
RPS17 |
|
-0.0592043399961363 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (95) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE30_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-96 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.307936197989644 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (96) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE450_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-96 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.633155646953449 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (96) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE450_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-96 |
6218 |
|
RPS17 |
|
0.307936197989644 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (96) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE450_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-96 |
6218 |
|
RPS17 |
|
-0.633155646953449 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (96) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE450_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-97 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-1.19423188135068 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (97) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE510_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-97 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.430123094329286 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (97) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE510_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-97 |
6218 |
|
RPS17 |
|
-1.19423188135068 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (97) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE510_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-97 |
6218 |
|
RPS17 |
|
-0.430123094329286 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (97) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
KYSE510_OESOPHAGUS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-98 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
-0.515302363497789 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (98) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L33_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-98 |
6218 |
|
RPS17 |
|
-0.0342418528155429 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (98) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L33_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-98 |
6218 |
|
RPS17 |
|
-0.515302363497789 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (98) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L33_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-98 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
-0.0342418528155429 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (98) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L33_PANCREAS |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-99 |
6218 |
|
RPS17L |
TRCN0000290975, TRCN0000291043 |
0.766748026978626 |
none |
|
|
RPS17L_1_00110 |
Context-specific genetic dependencies (99) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L363_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-99 |
6218 |
|
RPS17L |
TRCN0000074887, TRCN0000290976, TRCN0000291044 |
0.799159583104639 |
none |
|
|
RPS17L_2_11001 |
Context-specific genetic dependencies (99) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L363_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-99 |
6218 |
|
RPS17 |
|
0.766748026978626 |
none |
|
|
RPS17_1_00110 |
Context-specific genetic dependencies (99) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L363_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
GR00366-A-99 |
6218 |
|
RPS17 |
|
0.799159583104639 |
none |
|
|
RPS17_2_11001 |
Context-specific genetic dependencies (99) |
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies |
Cowley et al. |
2014 |
25984343 |
Cell line |
L363_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE |
shRNA abundance |
Next-generation sequencing |
TRC |
shRNA |
Genome-wide |
Fold change |
np (default cutoff applied: Z-score > 2 OR < -2) |
Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.) |
|
6218 |
6218 |
RPS17 |
|
-0.010000000000000009 |
none |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GR00376-A-1 |
6218 |
6218 |
RPS17 |
|
0.715292037 |
none |
|
|
|
Mitigators of SS1P-induced immunotoxicity |
Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity |
Pasetto et al. |
2015 |
25713356 |
Cell line |
KB cells |
Viability |
Luminescence |
Ambion Silencer Select Version 4 |
Genome-wide |
siRNA |
RSA P-value |
<0.001 |
SS1P was applied in a "high dose", ≈EC90, 13 ng/ml. Cutoff was derived from data submitted to Pubchem (ID 1117281). Reagent sequences but no ID |
GR00376-A-2 |
6218 |
6218 |
RPS17 |
|
0.005256536 |
none |
|
|
|
Sensitizers of SS1P-induced immunotoxicity |
Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity |
Pasetto et al. |
2015 |
25713356 |
Cell line |
KB cells |
Viability |
Luminescence |
Ambion Silencer Select Version 4 |
Genome-wide |
siRNA |
RSA P-value |
<0.001 |
SS1P was applied in a "low dose", ≈EC30, 3 ng/ml. Cutoff was derived from data submitted to PubChem (ID 1117281). Reagent sequences but no ID |
GR00378-A |
6218 |
|
RPS17 |
|
-1.37301466 |
none |
|
|
|
Poliovirus vaccine production |
Engineering Enhanced Vaccine Cell Lines To Eradicate Vaccine-Preventable Diseases: the Polio End Game |
van der Sanden et al. |
2015 |
26581994 |
Cell line |
HEp-2C |
Infection with Attenuated Poliovirus |
ELISA |
Dharmacon |
Genome-wide |
siRNA |
Z-score |
> |
For infection, a single lot of the attenuated Sabin type 2 poliovirus was used for the screen. Gene IDs were not provided, only the gene name/symbol |
|
6218 |
NM_001021 |
RPS17 |
|
85.765 |
none |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GR00386-A-1 |
6218 |
6218 |
RPS17 |
|
53.7414268462186 |
Decreased viability |
|
|
|
NOD2 stimulation by MDP |
A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-κB (NF-κB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion. |
Warner et al. |
2014 |
25170077 |
Cell line |
HEK293 stably expressing NOD2 |
Viability |
Luminescence |
Dharmacon |
Genome-wide |
siRNA |
Percentage growth |
Decreased: <70, increased: >120 |
Reagent IDs not provided |
GR00386-A-2 |
6218 |
6218 |
RPS17 |
|
27 |
none |
|
|
|
MDP-induced IL-8 secretion |
A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-κB (NF-κB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion. |
Warner et al. |
2014 |
25170077 |
Cell line |
HEK293 stably expressing NOD2 |
IL-8 secretion |
ELISA |
Dharmacon |
Genome-wide |
siRNA |
Percent inhibition of IL-8 secretion |
Increased: <-300, Decreased: >60 |
Concentration of IL-8 was measured from cell supernatants by sandwich ELISA. IL-8 values (pg/ml) were normalized to IL-8 secreted in cells treated with RIPK2-specific siRNA (100% inhibition) and non-targeting siRNA (0% inhibition). Secondary validating screen assessed 554 genes whose silencing affected MDP-induced IL-8 secretion in the primary screen. Final validated IL-8 regulators (positive or negative) are listed in the comments column. Reagent IDs not provided |