Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1003
• Symbol: CDH5
• Description: cadherin 5

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
1003	GO:0001932	IDA	involved_in	regulation of protein phosphorylation	23159740	Process
1003	GO:0006874	IDA	involved_in	intracellular calcium ion homeostasis	23159740	Process
1003	GO:0007043	IMP	involved_in	cell-cell junction assembly	23288152	Process
1003	GO:0007179	IDA	involved_in	transforming growth factor beta receptor signaling pathway	21168935	Process
1003	GO:0010628	IMP	involved_in	positive regulation of gene expression	26598555	Process
1003	GO:0030335	IDA	involved_in	positive regulation of cell migration	15572031	Process
1003	GO:0030513	IMP	involved_in	positive regulation of BMP signaling pathway	26598555	Process
1003	GO:0031115	IDA	involved_in	negative regulation of microtubule polymerization	23159740	Process
1003	GO:0031334	IMP	involved_in	positive regulation of protein-containing complex assembly	26598555	Process
1003	GO:0034332	IDA	involved_in	adherens junction organization	26598555	Process
1003	GO:0035307	IMP	involved_in	positive regulation of protein dephosphorylation	11950700	Process
1003	GO:0043114	IDA	involved_in	regulation of vascular permeability	26598555	Process
1003	GO:0043534	IMP	involved_in	blood vessel endothelial cell migration	31934175	Process
1003	GO:0044331	IDA	involved_in	cell-cell adhesion mediated by cadherin	26598555	Process
1003	GO:0045766	IGI	involved_in	positive regulation of angiogenesis	22391569	Process
1003	GO:0050728	IGI	involved_in	negative regulation of inflammatory response	28112401	Process
1003	GO:0070830	IMP	involved_in	bicellular tight junction assembly	25753039	Process
1003	GO:0098609	IDA	involved_in	cell-cell adhesion	15572031	Process
1003	GO:1902396	IMP	involved_in	protein localization to bicellular tight junction	25753039	Process
1003	GO:1903142	IMP	involved_in	positive regulation of establishment of endothelial barrier	23288152	Process
1003	GO:2000114	IMP	involved_in	regulation of establishment of cell polarity	20332120	Process
1003	GO:2000352	IMP	acts_upstream_of	negative regulation of endothelial cell apoptotic process	31934175	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
1003	GO:0005102	IPI	enables	signaling receptor binding	12088286	Function
1003	GO:0005515	IPI	enables	protein binding	15985432,17057644,18287330,18662404,20010843,20123964,20332120.....	Function
1003	GO:0008013	IPI	enables	beta-catenin binding	18287330	Function
1003	GO:0019903	IPI	enables	protein phosphatase binding	28926625	Function
1003	GO:0043184	IPI	enables	vascular endothelial growth factor receptor 2 binding	25893857	Function
1003	GO:0044325	IPI	enables	transmembrane transporter binding	19996314	Function
1003	GO:0070051	IMP	enables	fibrinogen binding	19413351	Function
1003	GO:0070700	IPI	enables	BMP receptor binding	26598555	Function
1003	GO:1990782	IPI	enables	protein tyrosine kinase binding	11950700	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
1003	GO:0005654	IDA	located_in	nucleoplasm		Component
1003	GO:0005886	IDA	located_in	plasma membrane	25978380	Component
1003	GO:0005911	IDA	located_in	cell-cell junction	15572031,19996314,20332120,21168935,23288152	Component
1003	GO:0005912	IDA	located_in	adherens junction	25978380,26598555	Component
1003	GO:0005912	IMP	located_in	adherens junction	26923917	Component
1003	GO:0009986	IDA	located_in	cell surface	23288152	Component
1003	GO:0031965	IDA	located_in	nuclear membrane		Component