Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 10297
• Symbol: APC2
• Description: APC regulator of WNT signaling pathway 2

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
10297	GO:0000226	IMP	involved_in	microtubule cytoskeleton organization	25753423	Process
10297	GO:0090090	IDA	involved_in	negative regulation of canonical Wnt signaling pathway	9823329,10021369	Process
10297	GO:0090090	IMP	involved_in	negative regulation of canonical Wnt signaling pathway	26393419	Process
10297	GO:0090630	IMP	involved_in	activation of GTPase activity	25753423	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
10297	GO:0005515	IPI	enables	protein binding	10644998,10646860	Function
10297	GO:0008013	IDA	enables	beta-catenin binding	9823329	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
10297	GO:0005737	IDA	located_in	cytoplasm	11691822	Component
10297	GO:0005794	IDA	located_in	Golgi apparatus	11691822	Component
10297	GO:0005829	IDA	located_in	cytosol		Component
10297	GO:0005881	IDA	colocalizes_with	cytoplasmic microtubule	10644998,11691822,25753423	Component
10297	GO:0005884	IDA	located_in	actin filament	11691822	Component
10297	GO:0015630	IDA	located_in	microtubule cytoskeleton	10644998	Component
10297	GO:0016342	IDA	part_of	catenin complex	9823329	Component
10297	GO:0030496	IDA	located_in	midbody		Component
10297	GO:0031258	IDA	located_in	lamellipodium membrane	11691822	Component
10297	GO:0045171	IDA	located_in	intercellular bridge		Component
10297	GO:0048471	IDA	located_in	perinuclear region of cytoplasm	10644998,10646860,11691822	Component